FedInvent™ Patents
Patent Details for Tuesday, September 14, 2010
This page was updated on Monday, March 27, 2023 at 01:53 AM GMT
Department of Health and Human Services (HHS)
US 07793659 | Breen |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Peter H. Breen (Irvine, California) |
ABSTRACT | A bymixer device and method which provides fast-response, accurate measurements of mixed inspired and/or expired gas fractions in open or closed ventilation circuits and/or in circle circuits used in anesthesia and/or critical care. The bymixer device may include a main flow channel and a bypass flow channel. The bypass flow channel includes a flow-restrictor (e.g, an orifice) that partially blocks the flow of respiratory gas through the bypass flow channel, a mixing chamber positioned upstream of the flow restrictor and a sampling apparatus (e.g., a port for withdrawing samples of gas from said mixing chamber and/or sensor(s) positioned within the mixing chamber). |
FILED | Tuesday, October 14, 2003 |
APPL NO | 10/530602 |
ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Surgery 128/204.180 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794469 | Kao et al. |
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ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Changquing C. Kao (Brentwood, Tennessee); J. Michael Fitzpatrick (Nashville, Tennessee); Robert F. Labadie (Nashville, Tennessee); Peter E. Konrad (Old Hickory, Tennessee) |
ABSTRACT | A surgical platform usable for performing a surgical procedure. In one embodiment, the surgical platform comprises a base portion configured to receive at least one probe; a plurality of adjustable legs configured to support the base portion, each adjustable legs having a first end portion and an opposite, second end potion defining a length therebetween; and at least one movable portion configured to adjust the length of at least one adjustable leg. |
FILED | Tuesday, November 07, 2006 |
APPL NO | 11/594700 |
ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 66/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794702 | Rosen et al. |
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ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); The Research Foundation of State University of New York (Albany, New York) |
INVENTOR(S) | Michael R. Rosen (New York, New York); Richard B. Robinson (Cresskill, New Jersey); Ira S. Cohen (Stony Brook, New York); Peter Brink (Setauket, New York) |
ABSTRACT | This invention provides a composition for delivery of a gene to a syncytial structure comprising stem cells incorporated with the gene. This invention also provides a composition for ion channel transfer which comprises stem cells incorporated with a compound in an amount sufficient to create ion channels. This invention also provides for a method of expressing a functional gene product in a syncytial structure comprising administering a composition, comprising stem cells that have been incorporated with a gene, to the syncytial structure. This invention further provides a method of expressing a functional ion channel in a syncytial structure comprising administering a composition, comprising stem cells that have been incorporated with a compound in an amount sufficient to create ion channels, to the syncytial structure. This invention also provides a composition for delivery of small molecules comprising stem cells incorporated with the small molecules or genes encoding the small molecules. |
FILED | Wednesday, January 15, 2003 |
APPL NO | 10/342506 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794713 | Sabbadini et al. |
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ASSIGNEE(S) | Lpath, Inc. (San Diego, California) |
INVENTOR(S) | Roger A. Sabbadini (Lakeside, California); Amy L. Cavalli (San Diego, California); William A. Garland (San Clemente, California) |
ABSTRACT | Monotherapies and combination therapies for treating hyperproliferative disorders are described, as are compositions for performing such methods. |
FILED | Friday, October 28, 2005 |
APPL NO | 11/261935 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794722 | Teyton et al. |
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ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The University of Chicago (Chicago, Illinois); Brigham Young University (Provo, Utah) |
INVENTOR(S) | Luc Teyton (Del Mar, California); Albert Bendelac (Chicago, Illinois); Paul B. Savage (Mapleton, Utah) |
ABSTRACT | Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune response are also disclosed. Further provided are vaccine preparations comprising NKT cell agonist compounds. |
FILED | Friday, June 29, 2007 |
APPL NO | 11/771128 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794725 | Barney et al. |
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ASSIGNEE(S) | Trimeris, Inc. (Durham, North Carolina) |
INVENTOR(S) | Shawn O'Lin Barney (Cary, North Carolina); Dennis Michael Lambert (Cary, North Carolina); Stephen Robert Petteway (Cary, North Carolina) |
ABSTRACT | The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID NO:1) peptide corresponding to amino acids 638 to 673 of the HIV-1LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells. |
FILED | Wednesday, June 07, 1995 |
APPL NO | 08/484223 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/188.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794727 | Marconi et al. |
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ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia) |
INVENTOR(S) | Richard Thomas Marconi (Midlothian, Virginia); Christopher Earnhart (Williamsburg, Virginia) |
ABSTRACT | A chimeric polyvalent recombinant protein for use as a vaccine and diagnostic for Lyme disease is provided. The chimeric protein comprises epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types. The OspC types may be associated with mammalian Borrelia infections. |
FILED | Wednesday, November 29, 2006 |
APPL NO | 11/564433 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/192.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794728 | Portnoy et al. |
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ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Daniel A. Portnoy (Albany, California); Mary O'Riordan (Alameda, California); Ian Glomski (Berkeley, California) |
ABSTRACT | Attenuated Listeria bacteria are provided. The subject bacteria are characterized by having a mutation in a gene chosen from the IpIA gene and the hly gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc. |
FILED | Thursday, May 29, 2003 |
APPL NO | 10/449710 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/200.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794729 | Paterson et al. |
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ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Yvonne Paterson (Philadelphia, Pennsylvania); Reshma Singh (Philadelphia, Pennsylvania) |
ABSTRACT | The present invention includes compositions, methods and kits for inducing an immune response to a tumor and for treating cancer with a Listeria vaccine strain expressing an antigen fused to a truncated LLO protein. |
FILED | Friday, September 24, 2004 |
APPL NO | 10/949667 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/200.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794731 | Mizel et al. |
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ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
INVENTOR(S) | Steven B. Mizel (Lewisville, North Carolina); Anna Nichole Honko (Fort Mills, South Carolina) |
ABSTRACT | The invention provides a fusion protein comprising a flagellin adjuvant and a Yersinia pestis antigen. Also provided are compositions comprising a flagellin adjuvant and a Yersinia pestis antigen. The invention also discloses methods of making a fusion protein comprising a flagellin adjuvant and a Yersinia pestis antigen. The invention further provides pharmaceutical formulations and methods for inducing an immune response against Yersinia pestis. |
FILED | Friday, December 16, 2005 |
APPL NO | 11/793159 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/234.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794733 | Judd et al. |
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ASSIGNEE(S) | The University of Montana (Missoula, Montana) |
INVENTOR(S) | Ralph C. Judd (Florence, Montana); D. Scott Manning (Missoula, Missouri) |
ABSTRACT | Nucleic acid and amino acid sequences of the Omp85 proteins of N. gonorrhoeae and N. meningitidis, and fragments thereof are useful in vaccine compositions, therapeutic compositions and diagnostic compositions for use in the prevention, treatment and diagnosis of non-symptomatic gonococcal infection or symptomatic disease and non-symptomatic meningococcal infection and symptomatic disease. Antibodies are developed to these proteins and also useful in the compositions and methods described herein. |
FILED | Thursday, June 26, 2003 |
APPL NO | 10/606618 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/250.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794751 | Chudzik et al. |
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ASSIGNEE(S) | SurModics, Inc. (Eden Prairie, Minnesota) |
INVENTOR(S) | Stephen J. Chudzik (St. Paul, Minnesota); Terrence P. Everson (Eagan, Minnesota); Richard A. Amos (St. Anthony, Minnesota) |
ABSTRACT | A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medicament in a form that permits the medicament to be released from the matrix in a prolonged, controlled, predictable and effective manner in vivo. A composition includes a polyether monomer, such as an alkoxy poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, a photoderivatized monomer, and a hydrophilic monomer such as acrylamide. |
FILED | Thursday, March 23, 2006 |
APPL NO | 11/387508 |
ART UNIT | 1614 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/487 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794926 | Altieri et al. |
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ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Dario Altieri (Worcester, Massachusetts); Robert Weiss (North Haven, Connecticut); Shannon Smith (Guilford, Connecticut); Victor Morris, legal representative (Guilford, Connecticut); Marcia Wheeler (Branford, Connecticut); Janet Plescia (Meriden, Connecticut) |
ABSTRACT | The present invention includes a method for diagnosing cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing. |
FILED | Tuesday, April 18, 2006 |
APPL NO | 11/405694 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794928 | Virgin et al. |
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ASSIGNEE(S) | Washington University (Saint Louis, Missouri) |
INVENTOR(S) | Herbert W. Virgin (St. Louis, Missouri); Christiane Wobus (Dexter, Michigan); Stephanie Karst (Shreveport, Louisiana) |
ABSTRACT | A norovirus-permissive cell culture infected with a norovirus, and methods of culturing a norovirus, are disclosed. Norovirus-permissive cells include dendritic cell-lineage cells, and macrophage-lineage cells, such as dendritic cells, and macrophages having a deficiency in a cellular anti-viral pathway such as a STAT-1-dependent pathway, an interferon receptor-dependent pathway, or a PKR-dependent pathway. Also disclosed are methods of screening anti-viral compounds against norovirus-permissive cells infected with norovirus, and norovirus adapted to grow in fibroblasts as well as macrophages that are not deficient in a cellular anti-viral pathway. Methods of making a norovirus vaccine are also disclosed. A replicative form of norovirus as well as its use in the development of an anti-viral agent and a polypeptide expression system are also described. Further disclosed are methods of detecting norovirus in a sample. |
FILED | Monday, February 04, 2008 |
APPL NO | 12/025327 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794929 | Baylin et al. |
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ASSIGNEE(S) | The Johns Hopkins University School of Medicine (Baltimore, Maryland) |
INVENTOR(S) | Stephen B. Baylin (Baltimore, Maryland); James Herman (Baltimore, Maryland); Hiromu Suzuki (Sapporo, Japan); David Sidransky (Baltimore, Maryland) |
ABSTRACT | A method of identifying epigenetically silenced genes, e.g., methylation silenced genes, in cancer cells is provided. In addition, methods of identifying a cancer by detecting epigenetic silencing of gene expression are provided, as are methods of treating a subject having such a cancer, for example, a colorectal cancer and/or gastric cancer. Reagents for practicing such methods also are provided. |
FILED | Friday, March 07, 2003 |
APPL NO | 10/384491 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794931 | Breaker et al. |
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ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Ronald R. Breaker (Guilford, Connecticut); Ali Nahvi (New Haven, Connecticut); Narasimhan Sudarsan (New Haven, Connecticut); Margaret S. Ebert (Hopewell, New Jersey); Wade Winkler (New Haven, Connecticut); Jeffrey E. Barrick (New Haven, Connecticut); John K. Wickiser (New Haven, Connecticut) |
ABSTRACT | It has been discovered that certain natural mRNAs serve as metabolite-sensitive genetic switches wherein the RNA directly binds a small organic molecule. This binding process changes the conformation of the mRNA, which causes a change in gene expression by a variety of different mechanisms. Modified versions of these natural “riboswitches” (created by using various nucleic acid engineering strategies) can be employed as designer genetic switches that are controlled by specific effector compounds. Such effector compounds that activate a riboswitch are referred to herein as trigger molecules. The natural switches are targets for antibiotics and other small molecule therapies. In addition, the architecture of riboswitches allows actual pieces of the natural switches to be used to construct new non-immunogenic genetic control elements, for example the aptamer (molecular recognition) domain can be swapped with other non-natural aptamers (or otherwise modified) such that the new recognition domain causes genetic modulation with user-defined effector compounds. The changed switches become part of a therapy regimen—turning on, or off, or regulating protein synthesis. Newly constructed genetic regulation networks can be applied in such areas as living biosensors, metabolic engineering of organisms, and in advanced forms of gene therapy treatments. |
FILED | Monday, September 22, 2003 |
APPL NO | 10/669162 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794940 | Jenkins |
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ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Robert B. Jenkins (Rochester, Minnesota) |
ABSTRACT | This document provides methods and materials related to detecting t(1;19) as well as methods and materials for identifying or assessing cancer within a mammal (e.g., a human). For example, methods for assessing the aggressiveness of a low-grade glioma in a human are provided. |
FILED | Friday, May 04, 2007 |
APPL NO | 11/744647 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794942 | Rice et al. |
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ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Charles M. Rice (New York, New York); Keril J. Blight (St. Louis, Missouri) |
ABSTRACT | HCV variants are described. The variants include polynucleotides comprising non-naturally occurring HCV sequences and HCV variants that have a transfection efficiency and ability to survive subpassage greater than HCV that have wild-type polyprotein coding regions. Expression vectors comprising the above polynucleotides and HCV variants are also described, as are the provision of cells and host cells comprising the expression vectors. Methods for identifying a cell line that is permissive for infection with HCV are also provided, as are vaccines comprising the above polynucleotides in a pharmaceutically acceptable carrier. Additionally, methods for inducing immunoprotection to HCV in a primate are described, as are methods for testing a compound for inhibiting HCV replication. |
FILED | Wednesday, December 19, 2007 |
APPL NO | 11/960391 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794944 | Felden |
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ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Brice Felden (Le Lou du Lac, France) |
ABSTRACT | The present invention is directed to eubacterial tmDNA sequences and the corresponding tmRNA sequences. The present invention is further directed to alignments of eubacterial tmDNA sequences and the use of the sequences and sequence alignments for the development of antibacterial drugs. The present invention is also directed to the use of the sequences for the development of diagnostic assays. |
FILED | Friday, June 27, 2008 |
APPL NO | 12/163564 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794949 | Schaeffer et al. |
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ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Anthony J. Schaeffer (Hinsdale, Illinois); Alisa E. Koch (Ann Arbor, Michigan) |
ABSTRACT | The present invention provides biomarkers of chronic pelvic pain syndrome for use in diagnosis, drug screening, therapy monitoring, research and therapeutic applications. In particular, the present invention provides MCP-1 and MIP-1α as biomarkers of chronic pelvic pain syndrome. |
FILED | Wednesday, April 27, 2005 |
APPL NO | 11/115747 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794951 | Kilpatrick et al. |
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ASSIGNEE(S) | University of Massachusetts Medical School (Boston, Massachusetts) |
INVENTOR(S) | Daniel Kilpatrick (Shrewsbury, Massachusetts); Hang Wang (Worcester, Massachusetts) |
ABSTRACT | The present invention relates to methods and compositions for modulating fertility. In particular the present invention provides cell lines and transgenic animals for use in identifying modulators of SREBP2gc transcription factors. The present invention further provides therapeutic agents that modulate SREBP2gc signaling for use as fertility modulators. |
FILED | Tuesday, October 18, 2005 |
APPL NO | 11/253012 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794956 | Feng et al. |
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ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
INVENTOR(S) | Gen-Sheng Feng (San Diego, California); Emilie Chapeau (San Diego, California) |
ABSTRACT | The invention is directed to the regulation of glucose homeostasis by modulating the activity of Grb2-associated binder 1 (Gab1) in hepatocytes. This invention also provides for a method for identifying compounds capable of modulating the glucose homeostasis regulatory activity of Gab1. In one aspect, the invention provides a method for identifying a compound that can effectively modulate glucose homeostasis wherein Gabl mediated MapK activity indicates that the candidate compound is an effective compound that modulates glucose homeostasis. In another aspect, the invention provides a method for identifying a compound that can effectively modulate the glucose homeostasis regulating activity of Gabl wherein MAPK is activated to phosphorylate Serine residue 612 of IRS-1, indicating that the candidate compound is an effective compound that modulates glucose homeostasis. In another aspect of the invention is provided a method for diagnosing Gab1 related disorders. |
FILED | Friday, November 12, 2004 |
APPL NO | 10/987384 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794957 | Kenyon et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
INVENTOR(S) | Cynthia Kenyon (San Francisco, California); Javier Apfeld (San Francisco, California); Andrew Dillin (Oakland, California); Delia Garigan (San Francisco, California); Ao-Lin A. Hsu (Albany, California); Josh Lehrer-Graiwer (San Francisco, California); Coleen Murphy (San Francisco, California) |
ABSTRACT | The present invention relates to regulation of adult lifespan in eukaryotes. More particularly, the present invention is directed to methods of assaying for activators of the heat shock factor 1 (HSF-1) protein, which increases lifespan when overexpressed in an organism. |
FILED | Friday, November 18, 2005 |
APPL NO | 11/282262 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794958 | Fazleabas |
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ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Asgerally T. Fazleabas (Chicago, Illinois) |
ABSTRACT | Provided herein is a method for diagnosing and monitoring endometriosis in a subject by measuring levels of the β-subunit of fibrinogen. |
FILED | Tuesday, January 22, 2008 |
APPL NO | 12/018010 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794961 | Reed et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
INVENTOR(S) | John C. Reed (Rancho Santa Fe, California); Quinn Deveraux (San Diego, California); Guy S. Salvesen (Encinitas, California); Ryosuke Takahashi (Tokyo, Japan); Natalie Roy (La Jolla, California) |
ABSTRACT | The present invention relates to an action between an inhibitor of apoptosis (IAP) protein and members of the caspase family of cell death proteases, for example, an interaction of the X chromosome linked IAP (XIAP) and caspase-3, caspase-7 or caspase-9, wherein the IAP regulates the activity of the caspases. The invention provides screening assays for identifying agents that alter the specific association of an IAP such as XIAP, c-IAP-1 or c-IAP-2 and a caspase such as caspase-3 or caspase-7. The invention also provides screening assays for identifying agents that alter the specific association of an IAP such as XIAP, c-IAP-1 or c-IAP-2 and a pro-caspase such as pro-caspase-9. In addition, the invention also provides methods for identifying agents that modulate the activity of a caspase in the presence of an IAP and that regulate the activation of a pro-caspase by an IAP. The invention further provides methods of reducing the severity of a pathologic condition in an individual by administering to the individual an agent that alters the caspase inhibitory activity of an IAP. In addition, the invention provides methods of modulating the ability of a population of cells to survive ex vivo by contacting the cells with an agent that alters the caspase inhibitory activity of an IAP in the cells. |
FILED | Tuesday, January 09, 2007 |
APPL NO | 11/651651 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794965 | Stock et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Signum Biosciences, Inc. (Monmouth Junction, New Jersey); The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Gregory Stock (Los Angeles, California); Jeffry B. Stock (Rocky Hill, New Jersey); Maxwell Stock (Rocky Hill, New Jersey); Scott Vafai (Boston, Massachusetts) |
ABSTRACT | The invention relates to methylated proteins that control protein phosphorylation, particularly phosphoesterases, such as PP2A. It relates to screening methods for determining agents that affect methylation of these proteins and thus also modulate the level of phosphorylation of phosphoproteins. It relates as well to the agents and to compositions comprising the agents. In a particular aspect in this regard the invention relates to agents that alter PP2A methylation and that thereby affect phosphorylation of phosphoproteins that play an important role in health or disease, such as the tau protein which is implicated in the etiology of Alzheimer's Disease. The invention further relates to diagnostic methods based on protein methylation levels, to compositions comprising agents for affecting methylation of proteins and for controlling the phosphate complement of phosphoproteins. Additionally, the invention relates to methods for administering the agents and compositions to affect methylation of proteins physiologically and to modulate the phosphate complement of phosphoproteins. Examples in this regard include agents and compositions that affect physiological activity of PP2A and alter the phosphate complement of phosphoproteins that are altered in disease. |
FILED | Thursday, March 13, 2003 |
APPL NO | 10/579369 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/21 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794978 | Chin et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Jason W. Chin (Cambridge, United Kingdom); T. Ashton Cropp (Bethesda, Maryland); J. Christopher Anderson (San Francisco, California); Peter G. Schultz (La Jolla, California) |
ABSTRACT | This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. |
FILED | Friday, October 26, 2007 |
APPL NO | 11/978172 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794998 | Switzer et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Johns Hopkins University (Baltimore, Maryland); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | William M. Switzer (Stone Mountain, Georgia); Walid Heneine (Atlanta, Georgia); Thomas M. Folks (Helotes, Texas); Nathan D. Wolfe (Los Angeles, California); Donald S. Burke (Pittsburgh, Pennsylvania); Eitel Mpoudi Ngole (Yaoundé , Cameroon) |
ABSTRACT | Disclosed are compositions and methods related to the isolation and identification of the primate T-lymphotropic viruses, HTLV-3 and HTLV-4. The diversity of HTLVs was investigated among central Africans reporting contact with NHP blood and body fluids through hunting, butchering, and keeping primate pets. Herein it is shown that this population is infected with a variety of HTLVs, including two retroviruses; HTLV-4 is the first member of a novel phylogenetic lineage that is distinct from all known HTLVs and STLVs; HTLV-3 falls within the genetic diversity of STLV-3, a group that has not previously been seen in humans. The present disclosure also relates to vectors and vaccines for use in humans against infection and disease. The disclosure further relates to a variety of bioassays and kits for the detection and diagnosis of infection with and diseases caused by HTLV-3 and HTLV-4 and related viruses. |
FILED | Saturday, February 24, 2007 |
APPL NO | 11/678596 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795009 | Heyduk |
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APPLICANT(S) | |
ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
INVENTOR(S) | Tomasz Heyduk (Ballwin, Missouri) |
ABSTRACT | The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules. |
FILED | Thursday, August 09, 2007 |
APPL NO | 11/836333 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795017 | Robinson et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Harriet L. Robinson (Atlanta, Georgia); Rama R. Amara (Atlanta, Georgia); Ted M. Ross (Aspinall, Pennsylvania); Rick A. Bright (Atlanta, Georgia) |
ABSTRACT | The present invention relates to novel plasmid constructs useful for the delivery of DNA vaccines. The present invention provides novel plasmids having a transcription cassette capable of directing the expression of a vaccine nucleic acid insert encoding immunogens derived from any pathogen, including fungi, bacteria and viruses. The present invention, however, is particularly useful for inducing in a patient an immune response against pathogenic viruses such as HIV, measles or influenza. Immunodeficiency virus vaccine inserts of the present invention express non-infectious HIV virus-like particles (VLP) bearing multiple viral epitopes. VLPs allow presentation of the epitopes to multiple histocompatability types, thereby reducing the possibility of the targeted virus escaping the immune response. Also described are methods for immunizing a patient by delivery of a novel plasmid of the present invention to the patient for expression of the vaccine insert therein. Optionally, the immunization protocol may include a booster vaccination that may be a live vector vaccine such as a recombinant pox virus or modified vaccinia Arbora vector. The booster live vaccine vector includes a transcription cassette expressing the same vaccine insert as the primary immunizing vector. |
FILED | Thursday, December 09, 2004 |
APPL NO | 11/009063 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795021 | Rao et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake, Utah) |
INVENTOR(S) | Mahendra S. Rao (Salt Lake City, Utah); Mark Noble (Brighton, New York); Margot Mayer-Proschel (Pittsford, New York) |
ABSTRACT | A glial precursor cell population from mammalian central nervous system has been isolated. These A2B5+ E-NCAM− glial-restricted precursor (GRP) cells are capable of differentiating into oligodendrocytes, A2B5+ process-bearing astrocytes, and A2B5− fibroblast-like astrocytes, but not into neurons. GRP cells can be maintained by regeneration in culture. GRP cells differ from oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells in growth factor requirements, morphology, and progeny. Methods of use of GRP cells are also disclosed. |
FILED | Friday, March 30, 2007 |
APPL NO | 11/694221 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/368 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795022 | Badylak |
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APPLICANT(S) | |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Stephen F. Badylak (West Lafayette, Indiana) |
ABSTRACT | A tissue graft construct for use in repairing diseased or damaged tissues is provided. The tissue graft construct comprises a matrix composition selected from the group consisting of liver basement membrane and extracts and hydrolysates thereof, and processed collagen from vertebrate non-submucosal sources, added endothelial cells, and at least one additional preselected, exogenous population of cells which enhance the initiation of vessel-like structures in the grant. The preselected population of cells can be a population of non-keratinized or keratinized epithelial cells or a population of mesodermally derived cells selected from the group consisting of fibroblasts, smooth muscle cells, skeletal muscle cells, cardiac muscle cells, multi-potential progenitor cells, pericytes, osteogenic cells, and any other suitable cell type, preferably selected based on the tissue to be repaired. Methods for enhancing the vascularization in vivo of these tissue graft constructs and for preparing these graft constructs are also provided. |
FILED | Friday, May 02, 2003 |
APPL NO | 10/428355 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/371 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795033 | McMahon et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia); Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Francis J. McMahon (Bethesda, Maryland); Gonzalo E. Laje (Potomac, Maryland); Silvia Paddock (Solna, Sweden); Husseini K. Manji (Titusville, New Jersey); A. John Rush (Singapore, Singapore); Alexander F. Wilson (Phoenix, Maryland) |
ABSTRACT | The invention provides a method for determining the outcome of treatment with an antidepressant medication in a patient. In particular, the invention provides a method of screening patients to identify those patients with a decreased risk of non-response to treatment with antidepressant medication by obtaining a sample of genetic material from the patients, and then assaying the sample for the presence of a genotype which is associated with a decreased risk of non-response to treatment with antidepressant medication. The genotype is characterized by a polymorphism in the genes HTR2A, GRIK4, BCL2, and a combination thereof. |
FILED | Wednesday, March 19, 2008 |
APPL NO | 12/051494 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/94 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795202 | Fallon et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Neurorepair, Inc. (San Francisco, California) |
INVENTOR(S) | James H. Fallon (Irvine, California); Richard M. Kinyamu (Irvine, California) |
ABSTRACT | The invention provides methods of treating a subject having a disease, disorder or condition of the central nervous system. The methods include administering TGF-α polypeptides, related polypeptides, fragments and mimetics thereof useful in stimulating progenitor cell or stem cell proliferation, migration and differentiation. The methods of the invention are useful to treat and prophylactically ameliorate neurological tissue injury in vivo. |
FILED | Monday, June 10, 2002 |
APPL NO | 10/167384 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795208 | Sartorelli et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Salk Institute for Biological Study (La Jolla, California); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Vittorio Sartorelli (Bethesda, Maryland); Pier Lorenzo Puri (San Diego, California) |
ABSTRACT | A method of enhancing progenitor cell differentiation, including enhancing myogenesis, neurogenesis, and hematopoiesis, by contacting a progenitor cell with an effective amount of a deacetylase inhibitor (DI). The progenitor cell can be part of cell culture, such as a cell culture used for in vitro or in vivo analysis of progenitor cell differentiation, or can be part of an organism, such as a human or other mammal. Contacting the progenitor cell with a DI can lead to enhancement of expression of terminal cell-type specific genes in the progenitor cell, such as enhancing expression of muscle-specific genes in myoblasts. Administering a DI to a subject also can provide some prophylactic or therapeutic effect for inhibiting, preventing, or treating associated with a degeneration or loss of tissue. The DI can be administered to a subject as part of a pharmaceutical composition. |
FILED | Friday, May 04, 2007 |
APPL NO | 11/800151 |
ART UNIT | 1614 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795217 | Adra |
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APPLICANT(S) | |
ASSIGNEE(S) | Chaker N. Adra (Boston, Massachusetts) |
INVENTOR(S) | Chaker N. Adra (Boston, Massachusetts) |
ABSTRACT | In some aspects, the invention provides methods and compositions including HTm4, an HTm4 activator, and/or an HTm4 variant to potentiate a KAP phosphatase activity and or inhibit a CDK2 kinase activity. In some embodiments, a functional C-terminal fragment of HTm4 is provided. In other aspects, the invention provides methods and compositions including an HTm4 inhibitor to inactivate or decrease the activation of a KAP phospatase activity and/or activate or relieve the inhibition on a CDK2 kinase activity. Certain aspects of the invention relate to therapeutic compositions and methods for either inhibiting or promoting cell proliferation. |
FILED | Wednesday, July 18, 2007 |
APPL NO | 11/779381 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795219 | Dewhirst et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Mark W. Dewhirst (Durham, North Carolina); Jonathan S. Stamler (Chapel Hill, North Carolina); Timothy J. McMahon (Durham, North Carolina); Pierre Sonveaux (Ottignies-Louvain-la-Neuve, Belgium) |
ABSTRACT | The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders associated with hypoxia in subjects, methods for increasing sensitivity of tumors to radiation and/or chemotherapy treatments, methods for delaying tumor growth in subjects, and methods for inhibiting tumor blood vessel growth in subjects. In some embodiments, the presently disclosed methods involve administering to subjects in need thereof a first composition selected from the group consisting of a nitrosylated hemoglobin and an agent that induces nitrosylation of endogenous hemoglobin in the subject and a second composition comprising a hyperoxic gas. In some embodiments, the presently disclosed methods also include treating a tumor with radiation therapy, chemotherapy, photodynamic therapy, immunotherapy, or combinations thereof. Also provided are inhalable gases that can be employed in the presently disclosed methods. |
FILED | Monday, January 07, 2008 |
APPL NO | 12/006849 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795220 | Gardella et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Bristol-Myers Squibb Company (Princeton, New Jersey) |
INVENTOR(S) | Thomas J. Gardella (Needham, Massachusetts); John T. Potts, Jr. (Charlestown, Massachusetts); Henry M. Kronenberg (Boston, Massachusetts); Naoto Shimizu (Shizuoka, Japan) |
ABSTRACT | The present invention relates to conformationally constrained parathyroid hormone (PTH) analogs and derivatives of those analogs. The invention also provides methods of preparing and using the PTH analogs. Further, the invention encompasses compositions and methods for use in limiting undesired bone loss in a vertebrate at risk of such bone loss, in treating conditions that are characterized by undesired bone loss or by the need for bone growth, e.g. in treating fractures or cartilage disorders and for raising camp levels in cells where deemed necessary. |
FILED | Wednesday, March 19, 2003 |
APPL NO | 10/549592 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/14 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795227 | Kriegler et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Steven M. Kriegler (Madison, Wisconsin); Avtar S. Roopra (Madison, Wisconsin); Thomas P. Sutula (Madison, Wisconsin); Carl E. Stafstrom (Madison, Wisconsin) |
ABSTRACT | This invention provides methods for alleviating paroxysmal disorders in an animal, particularly epilepsy, by modulating glycolysis in brain cells. |
FILED | Friday, June 17, 2005 |
APPL NO | 11/155200 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/23 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795242 | Van Rhijn et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Ildiko Van Rhijn (Amsterdam, Netherlands); David C. Young (Haverhill, Massachusetts); D. Branch Moody (West Roxbury, Massachusetts) |
ABSTRACT | Novel antigens are provided herein. The antigens are associated with recognition of CD1 molecules by T cells. These antigens can be used as antigens, adjuvants or as immunomodulatory agents in a variety of therapeutic and prophylactic applications. |
FILED | Friday, October 15, 2004 |
APPL NO | 10/966874 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795299 | Lee et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Kuo-Hsiung Lee (Chapel Hill, North Carolina); Xihong Wang (Chapel Hill, North Carolina); Kenneth F. Bastow (Chapel Hill, North Carolina); Tian-Shung Wu (Tainan, Taiwan) |
ABSTRACT | Compounds of Formulas I-II are described, along with methods of using such compounds for the treatment of cancer and pharmaceutical formulations thereof. |
FILED | Friday, January 16, 2009 |
APPL NO | 12/355309 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/453 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795380 | Rice et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
INVENTOR(S) | Kevin G. Rice (Iowa City, Iowa); Garrett R. Rettig (Iowa City, Iowa); Nicholas J. Baumhover (Iowa City, Iowa) |
ABSTRACT | Compositions and methods are described for non-viral nucleic acid delivery. A targeting peptide capable of mediating targeting to a cell or subcellular compartment is derivatized with a photoaffinity label. Following an ionic interaction with a polynucleotide, such as DNA, and photolysis, the bioactive peptide becomes covalently attached to the DNA. Upon contact with a cell, the peptide facilities uptake of the peptide-polynucleotide conjugate into the cell or subcellular compartment. Methods for using this system for delivery of structural genes, including reporter genes, and detection of expression using bioluminescence are also described. |
FILED | Monday, June 04, 2007 |
APPL NO | 11/757848 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795381 | Celis |
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APPLICANT(S) | |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Esteban Celis (Rochester, Minnesota) |
ABSTRACT | Methods and materials for inducing anti-tumor responses in melanoma patients are disclosed. These methods and materials involve gp100-derived polypeptides that contain both a helper T-cell epitope and a cytotoxic T-cell epitope. |
FILED | Tuesday, January 22, 2008 |
APPL NO | 12/018022 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795389 | Sun et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | LuZhe Sun (San Antonio, Texas); Andrew P. Hinck (San Antonio, Texas) |
ABSTRACT | Anti-cancer agents and/or transforming growth factor beta (TGF-beta or TGFβ) antagonists are disclosed, where the agents and/or antagonists include a therapeutically effective amount of a combination of therapeutically active portions of sRII and therapeutically active portions of sRIII or a fusion polypeptide or protein comprising therapeutically active portions of sRII and therapeutically active portions of sRIII. Methods for preventing, treating and/or ameliorating the symptoms of cancer are also disclosed based on administering an effective amount of a composition of this invention. |
FILED | Wednesday, September 28, 2005 |
APPL NO | 11/238172 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795394 | Conrad et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
INVENTOR(S) | Chris Conrad (Medford, Massachusetts); Peter Davies (Rye, New York) |
ABSTRACT | The present invention provides an isolated nucleic acid sequence encoding saitohin (STH), an isolated nucleic acid sequence that hybridizes to said sequence, and a purified protein encoded by said nucleic acid sequences. The present invention also provides a purified STH protein, and a method of making STH protein. The present invention is further directed to an antibody specific for STH, and a method for producing said antibody. Additionally, the present invention discloses a vector comprising a nucleic acid sequence encoding STH, a host cell transformed with said vector, and transgenic nonhuman animals. The present invention further provides methods for determining whether a subject has, or is at increased risk for developing, a neurodegenerative disease, and for assessing said subject's prognosis. Finally, the present invention discloses kits for determining whether a subject has, or is at increased risk for developing, a neurodegenerative disease. |
FILED | Thursday, November 15, 2007 |
APPL NO | 11/985584 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795396 | Cox, III |
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APPLICANT(S) | |
ASSIGNEE(S) | Bolder Biotechnology, Inc. (Boulder, Colorado) |
INVENTOR(S) | George N. Cox, III (Louisville, Colorado) |
ABSTRACT | The growth hormone supergene family comprises greater than 20 structurally related cytokines and growth factors. A general method is provided for creating site-specific, biologically active conjugates of these proteins. The method involves adding cysteine residues to non-essential regions of the proteins or substituting cysteine residues for non-essential amino acids in the proteins using site-directed mutagenesis and then covalently coupling a cysteine-reactive polymer or other type of cysteine-reactive moiety to the proteins via the added cysteine residue. Disclosed herein are preferred sites for adding cysteine residues or introducing cysteine substitutions into the proteins, and the proteins and protein derivatives produced thereby. |
FILED | Wednesday, March 02, 2005 |
APPL NO | 11/071098 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/351 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795397 | Lagarias et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | John Clark Lagarias (Davis, California); Amanda J. Fischer (Davis, California) |
ABSTRACT | This invention provides fluorescent adducts that emit in the far red and/or near infrared. In certain embodiments, the adducts comprise a mutant apoprotein and a bilin. |
FILED | Thursday, May 05, 2005 |
APPL NO | 11/123692 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/370 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795411 | Scholler et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
INVENTOR(S) | Nathalie Scholler (Seattle, Washington); Barbara Garvik (Seattle, Washington) |
ABSTRACT | The present invention provides compositions and methods for generating in vivo biotinylated, secreted recombinant polypeptides comprising recombinantly co-expressing in a yeast cell (a) a secreted recombinant polypeptide comprising a biotin accepting site; and (b) a biotin ligase fused to the golgi localization domain so that the biotin ligase is localized to the golgi of the yeast cell where it acts on the biotin-accepting site of the secreted polypeptide as it transits the secretory system. |
FILED | Wednesday, January 31, 2007 |
APPL NO | 11/669811 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Organic compounds 536/23.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795457 | Fu et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Kosan Biosciences Incorporated (Princeton, New Jersey) |
INVENTOR(S) | Hong Fu (Union City, California); Yaoquan Liu (Castro Valley, California) |
ABSTRACT | Carbamate compounds having a structure represented by formula I (where R1, R2, R3, R4, R5 and R6 are as defined herein) are useful as anti-tumor agents. |
FILED | Wednesday, February 20, 2008 |
APPL NO | 12/070835 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 549/419 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795868 | Larson et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Peder E. Larson (Oakland, California); John M. Pauly (Stanford, California); Daniel B. Vigneron (Corte Madera, California); Albert Chen (San Francisco, California); Adam B. Kerr (Menlo Park, California) |
ABSTRACT | A method for performing magnetic resonance spectroscopy is described. The method generally includes applying a tailored multiband spectral-spatial radio frequency excitation pulse to a sample including a first species and at least a second species having a different resonant frequency than the first species. The multiband excitation pulse excites the first species according to a first amplitude and excites the second species according to a second amplitude that is substantially greater than the first amplitude. Data is acquired from the sample. The acquired data is then utilized to generate a spectroscopic output. By way of example, the spectroscopic output is a spectroscopic image. In particular embodiments, the data for the first and second species is acquired dynamically over an observation window of time. |
FILED | Wednesday, October 08, 2008 |
APPL NO | 12/247940 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Measuring and testing 324/307 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796371 | Xie et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Jun Xie (Pasadena, California); Jason Shih (Yorba Linda, California); Yu-Chong Tai (Pasadena, California) |
ABSTRACT | A micro fluidic device and method for capacitive sensing. The device includes a fluid channel including an inlet at a first end and an outlet at a second end, a cavity region coupled to the fluid channel, and a polymer based membrane coupled between the fluid channel and the cavity region. Additionally, the device includes a first capacitor electrode coupled to the membrane, a second capacitor electrode coupled to the cavity region and physically separated from the first capacitor electrode by at least the cavity region, and an electrical power source coupled between the first capacitor electrode and the second capacitor electrode and causing an electric field at least within the cavity region. The polymer based membrane includes a polymer. |
FILED | Monday, July 30, 2007 |
APPL NO | 11/830581 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/283.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797040 | Pesaran et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Bijan Pesaran (Los Angeles, California); Richard A. Andersen (La Canada, California) |
ABSTRACT | Prosthetic devices, methods and systems are disclosed. Eye position and/or neural activity of a primate are recorded and combined. The combination signal is compared with a predetermined signal. The result of the comparison step is used to actuate the prosthetic device. |
FILED | Thursday, December 15, 2005 |
APPL NO | 11/300965 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/545 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797058 | Mrva et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | NDI Medical, LLC (Cleveland, Ohio) |
INVENTOR(S) | Joseph J. Mrva (Willoughby Hills, Ohio); James Coburn (Cleveland Heights, Ohio); Robert B. Strother (Willoughby Hills, Ohio); Geoffrey B. Thrope (Shaker Heights, Ohio) |
ABSTRACT | Devices, systems, and methods for recording, and/or stimulation, and/or blocking of a nerve make use of a molded cuff electrode. An electrically conductive surface is coupled to an inside surface of the cuff's elastic body. The electrically conductive surface and the body assume a coiled configuration in its natural state. An applicator tool having a body and a slider are used to implant the cuff electrode about a nerve. |
FILED | Thursday, August 04, 2005 |
APPL NO | 11/196995 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Surgery: Light, thermal, and electrical application 67/118 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 07793374 | Anderson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Robert W. Anderson (Alexandria, Virginia); Sean M. Gallagher (Philadelphia, Pennsylvania); Kellie L. Redcay (Pottstown, Pennsylvania); Ryan T. Hayleck (Fulton, Maryland); John F. O'Dea (Laurel, Maryland); Stuart G. Ullman (Kensington, Maryland) |
ABSTRACT | As typically embodied, the inventive ramp system for bridging between structures (e.g., marine vessels) includes a hydraulic elevator device and a ramp unit. The ramp unit includes three adjoining planar members, the ramp member (the main ramp body) being pivotably connected at each end to one of the two platform members. The hydraulic elevator device includes the coaxial combination of a cylinder and a piston, the piston being translatable along and pivotable about the axis. The cylinder-piston combination is secured, axis vertical, to a first structure, with one of the ramp unit's platform members attached atop the piston. In order to position the other (unattached) platform member upon a selected (e.g., horizontal) location of a second structure, the ramp unit is configurable in terms of the attached platform member's height, the ramp unit's horizontal rotation angle, and the respective vertical rotation angles of the ramp unit's two pivotable connections. |
FILED | Friday, April 20, 2007 |
APPL NO | 11/788422 |
ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Bridges 014/69.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07793606 | Olivier et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | ION Geophysical Corporation (Houston, Texas) |
INVENTOR(S) | André W. Olivier (River Ridge, Louisiana); Lloyd Joseph LaCour, Jr. (Sequim, Washington) |
ABSTRACT | A position controller capable of controlling the depth or lateral position of a towed array. The position controller comprises a tubular fuselage from which a pair of wings may be extended over a range of sweep angles between fully open and stowed positions. In fully or partly open positions, two wings present a positive angle of attack relative to the axis of the fuselage. In the stowed position, the wings are fully retracted into a wing receptacle within the fuselage for unfettered passage into and out of a submarine on the array deployment and retrieval handling system. |
FILED | Tuesday, February 13, 2007 |
APPL NO | 11/674539 |
ART UNIT | 3617 — Printing/Measuring and Testing |
CURRENT CPC | Ships 114/245 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07793703 | Wood et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Century Inc. (Traverse City, Michigan) |
INVENTOR(S) | Thomas D. Wood (Houghton, Michigan); Neil Anderson (Calumet, Michigan); Andrew Halonen (Calumet, Michigan) |
ABSTRACT | The present invention relates to a metal matrix composite (MMC) and the method of manufacturing the MMC. The MMC includes a preform formed from a composition having ceramic particles and ceramic fibers. The metal matrix composite also includes a support element formed from a metal where the metal impregnates through the preform. The method of forming the MMC includes the step of extruding the composition through a multi-screw extruder to form an extrudate. The method also includes the step of heating the preform and positioning the preform within a mold. The method further includes the step of heating the metal for forming a molten metal and injecting the molten metal into a cavity of the mold under pressure for infiltrating the preform with the molten metal. The method also includes cooling the molten metal to solidify the molten metal and form the metal matrix composite and removing the metal matrix composite from the mold. |
FILED | Thursday, July 17, 2008 |
APPL NO | 12/174986 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Metal founding 164/97 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07793795 | Schneider et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | David B. Schneider (Ashland, Massachusetts); Peter G. Lavigne (Upton, Massachusetts) |
ABSTRACT | A water storage and delivery assembly includes stackable compartments, each compartment having a planar bottom wall, opposed side walls, and opposed end walls, forming a reservoir. Frusto-conically shaped conduits having open large first ends are fixed to peripheries of openings in the bottom walls, and open smaller second ends are disposed below upper edges of the side and end walls. The assembly further includes a bottom-most compartment of the same construction but having no openings in the bottom wall thereof. Water poured into a first conduit is flowable through a plurality of first conduits to the bottom-most compartment while air escapes upwardly through a series of second conduits, the water rising until all the compartments of the assembly are filled. Each compartment is provided with an outlet operable to permit the water to travel from a compartment to an exothermic mass. |
FILED | Monday, March 20, 2006 |
APPL NO | 11/384461 |
ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Receptacles 220/4.270 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794102 | Shemwell et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | David M. Shemwell (Newcastle, Washington); Weihao Alexander Long (Kirkland, Washington); Michael Perry Challenger (Bothell, Washington); Robert Lee Fuhriman, Jr. (Bothell, Washington); Donald Limuti (Kirkland, Washington) |
ABSTRACT | An apparatus produces a “dazzling” effect: disorientation and temporary and fully reversible blindness in subjects for the purpose of threat deterrence in both civilian law enforcement and military engagements without the use of lasers. A plurality of light emitting diodes (LEDs) capable of intense illumination is provided. Light emitted by each LED is pulsed and focused by reflective optics to produce a pulsed beam of sufficient intensity that the combined effect of the beams from the LEDs induces dazzling in subject viewers in the target range. Further included in or ancillary to the invention are a power source for powering the LEDs a signal source and controller for controlling their illumination and pulsing, and a shield suitable for protecting a user against projectiles. |
FILED | Thursday, May 15, 2008 |
APPL NO | 12/152539 |
ART UNIT | 2875 — Optics |
CURRENT CPC | Illumination 362/109 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794557 | Hui et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Inframat Corporation (Farmington, Connecticut) |
INVENTOR(S) | Shiqiang Hui (Vancouver, Canada); Yide Zhang (Storrs, Connecticut); Danny Xiao (Willington, Connecticut); Mingzhong Wu (Fort Collins, Colorado) |
ABSTRACT | A precursor tape casting method is one in which chemical precursors are converted into a final chemical phase from green tapes to products. Because chemical precursors are employed rather than the final powder materials, sintering is not required to form the material. Lower annealing temperatures instead of high temperature sintering allow the formation of grains of about 1 to about 100 nanometers in the final material. In addition, when the final material is a magnetic/insulator composite, improved magnetic properties may be obtained. |
FILED | Friday, June 10, 2005 |
APPL NO | 11/150592 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/89.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794580 | Withers et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Materials and Electrochemical Research Corp. (Tucson, Arizona) |
INVENTOR(S) | James C. Withers (Tucson, Arizona); Raouf O. Loutfy (Tucson, Arizona) |
ABSTRACT | A method of winning a metal from its oxide ore by heating the ore in a partial vacuum or under an inert atmosphere in the presence of a reductant. The resulting product may be further reduced electrochemically to produce a purer metal. |
FILED | Tuesday, December 06, 2005 |
APPL NO | 11/294872 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/560 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794657 | Stewart |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cantimer, Inc. (Menlo Park, California) |
INVENTOR(S) | Ray F. Stewart (Redwood City, California) |
ABSTRACT | A device is disclosed which is a highly sensitive and selective sensor. The device is comprised of a sensor material secured into a fixed position on substrate, a deformable arm and a signaling component which creates a detectable signal in response to movement of the arm. The sensitivity of the device is enhanced by using a sensor material which undergoes a dramatic change in volume which may be accompanied by a phase change in response contact with a target such a molecule of interest. The selectivity of the device is enhanced by incorporating highly specific binding receptors (e.g. antibodies) into the sensor material which receptors bind to specific targets (e.g. peptide epitopes). The binding of the target molecule to the receptor causes the sensor material to change dramatically in volume thereby moving the arm causing the signaling component (e.g. a piezoresistor) to create a detectable signal (e.g. change in resistance) thereby indicating the present of the target. |
FILED | Friday, May 28, 2004 |
APPL NO | 10/857634 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794683 | Forohar et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Farhad Forohar (Laplata, Maryland); Craig Whitaker (Annapolis, Maryland); William M. Koppes (Adelphi, Maryland) |
ABSTRACT | The present invention relates to methods for the preparation of a carbon nanotube from an amino-functionalized carbon nanotube via an amino oxidation reaction. The carbon nanotube includes nitrogen based functional groups that are covalently attached to lattice carbons of the carbon nanotube, directly or via a chemical linker. The synthetic methods of the present invention allow the nitrogen based functional groups to be attached selectively to one of two distinct regions of the carbon nanotube, and thus enable the synthesis of a carbon nanotube having nitrogen based functional groups substantially concentrated on the ends and/or the sidewall of the carbon nanotube. |
FILED | Friday, April 14, 2006 |
APPL NO | 11/417291 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794729 | Paterson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Yvonne Paterson (Philadelphia, Pennsylvania); Reshma Singh (Philadelphia, Pennsylvania) |
ABSTRACT | The present invention includes compositions, methods and kits for inducing an immune response to a tumor and for treating cancer with a Listeria vaccine strain expressing an antigen fused to a truncated LLO protein. |
FILED | Friday, September 24, 2004 |
APPL NO | 10/949667 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/200.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794795 | Detty et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
INVENTOR(S) | Michael R. Detty (Rochester, New York); Michael D. Drake (Glendale, California); Ying Tang (Amherst, New York); Frank V. Bright (Williamsville, New York) |
ABSTRACT | The present invention relates to a coating composition including a sol-gel matrix and a dendrimeric organochalcogeno derivative and a system including the coating composition and a substrate. The present invention also relates to a method of preventing fouling of surfaces subjected to a marine environment. |
FILED | Friday, July 06, 2007 |
APPL NO | 11/774437 |
ART UNIT | 1796 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Coating processes 427/387 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794808 | Dudt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Philip John Dudt (Rockville, Maryland); Roshdy George S. Barsoum (McLean, Virginia) |
ABSTRACT | A typical inventive embodiment describes a tubular shape and comprises a rigid outer layer, an elastomeric middle layer and a rigid inner layer. The elastomeric material is a strain-rate-sensitive polymer (e.g., polyurethane or polyurea) having a Young's modulus of approximately 700-1000 psi at 100% strain, and strong strain-rate-sensitivity in approximately the 103/second-106/second range. By the time that the projectile reaches the rigid inner layer, a projectile that impacts the three-layer system (commencing at the rigid outer layer) is structurally and kinetically diminished in its destructiveness by the rigid outer layer together with the elastomeric middle layer. Furthermore, the elastomeric middle layer becomes more rigid during a brief period in which it absorbs energy from the projectile, then again becomes elastic in a manner formative of a membrane covering the rigid inner layer. The elastomeric membrane tempers leakage if rupturing of the rigid inner layer has occurred. |
FILED | Monday, May 22, 2006 |
APPL NO | 11/443845 |
ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/36.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794834 | Naciri et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jawad Naciri (Herndon, Virginia); Hong Jeon (Carlsbad, California); Patrick N Keller (Bures sur Yvette, France); Banahalli R Ratna (Woodbridge, Virginia) |
ABSTRACT | A method of making a liquid crystalline fiber is disclosed. A copolymer having a liquid crystalline side group and a crosslinking side group is crosslinked. A fiber of the crosslinking copolymer is drawn before the crosslinking reaction is complete. |
FILED | Wednesday, June 21, 2006 |
APPL NO | 11/425409 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Stock material or miscellaneous articles 428/394 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794961 | Reed et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
INVENTOR(S) | John C. Reed (Rancho Santa Fe, California); Quinn Deveraux (San Diego, California); Guy S. Salvesen (Encinitas, California); Ryosuke Takahashi (Tokyo, Japan); Natalie Roy (La Jolla, California) |
ABSTRACT | The present invention relates to an action between an inhibitor of apoptosis (IAP) protein and members of the caspase family of cell death proteases, for example, an interaction of the X chromosome linked IAP (XIAP) and caspase-3, caspase-7 or caspase-9, wherein the IAP regulates the activity of the caspases. The invention provides screening assays for identifying agents that alter the specific association of an IAP such as XIAP, c-IAP-1 or c-IAP-2 and a caspase such as caspase-3 or caspase-7. The invention also provides screening assays for identifying agents that alter the specific association of an IAP such as XIAP, c-IAP-1 or c-IAP-2 and a pro-caspase such as pro-caspase-9. In addition, the invention also provides methods for identifying agents that modulate the activity of a caspase in the presence of an IAP and that regulate the activation of a pro-caspase by an IAP. The invention further provides methods of reducing the severity of a pathologic condition in an individual by administering to the individual an agent that alters the caspase inhibitory activity of an IAP. In addition, the invention provides methods of modulating the ability of a population of cells to survive ex vivo by contacting the cells with an agent that alters the caspase inhibitory activity of an IAP in the cells. |
FILED | Tuesday, January 09, 2007 |
APPL NO | 11/651651 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795015 | Guttieri et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Mary C. Guttieri (Myersville, Maryland); Connie S. Schmaljohn (Frederick, Maryland) |
ABSTRACT | Three vectors are described which allow the conversion of Fab fragments into or single chain Fv fragments into full-length antibody molecules. Methods for using the vectors and the resulting antibodies are also described. |
FILED | Friday, March 08, 2002 |
APPL NO | 10/094546 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795120 | Price et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jack L. Price (Derwood, Maryland); Noel A. Guardala (Columbia, Maryland); Michael G. Pravica (Henderson, Nevada) |
ABSTRACT | A 13C diamond is doped by proton induced transmutation. P-type doping is achieved by the 13C(p,αγ)10B reaction. N-type doping is achieved by the 13C(p,γ)14N reaction. The transmutation reaction that occurs is determined by selection of proton beam energy. Stacks of junctions each calculated to be in the order of 10 nm thick have been achieved. |
FILED | Wednesday, September 16, 2009 |
APPL NO | 12/560622 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/512 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795389 | Sun et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | LuZhe Sun (San Antonio, Texas); Andrew P. Hinck (San Antonio, Texas) |
ABSTRACT | Anti-cancer agents and/or transforming growth factor beta (TGF-beta or TGFβ) antagonists are disclosed, where the agents and/or antagonists include a therapeutically effective amount of a combination of therapeutically active portions of sRII and therapeutically active portions of sRIII or a fusion polypeptide or protein comprising therapeutically active portions of sRII and therapeutically active portions of sRIII. Methods for preventing, treating and/or ameliorating the symptoms of cancer are also disclosed based on administering an effective amount of a composition of this invention. |
FILED | Wednesday, September 28, 2005 |
APPL NO | 11/238172 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795565 | Bock |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Gregory F. Bock (Feasterville Trevose, Pennsylvania) |
ABSTRACT | A guided missile or projectile and associated guidance control are provided to control a path to a point of intersection with a potentially moving target. A new path is repetitively recomputed and acceleration orthogonal to the path is applied to minimize heading error and thereby to converge on the target. The gain of the control function is partly proportional to heading error, but the gain is reduced approaching the point of convergence. In this way, the guidance control is more responsive to actual variance of the true heading error and is less responsive to random error in sensing the target heading, which random error would otherwise increase in its contribution to corrective guidance movements approaching the point of intersection. |
FILED | Thursday, January 03, 2008 |
APPL NO | 11/968705 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Aeronautics and astronautics 244/3.150 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795573 | Sprafke |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Teledyne Scientific and Imaging, LLC (Thousand Oaks, California) |
INVENTOR(S) | Thomas Sprafke (Malibu, California) |
ABSTRACT | An imaging device and method of fabricating the same is disclosed. The imaging device may include an imaging sensor base, an image detector and a multilayer board. The imaging sensor base has a bonded hub having uniform flatness. The mounting hub sized to fit into a receptacle in the multilayer board. The image detector sized to match a size of the imaging sensor base and bonded to a top surface of the imaging sensor base. The imaging device may also include a readout integrated circuit (ROIC) sized to substantially match the size of the imaging sensor base and disposed on the image detector. A plurality of equi-spaced flexures and receptacles for receiving the plurality of flexures may also be used to maintain positional stability and minimize thermal strain. |
FILED | Monday, November 17, 2008 |
APPL NO | 12/272450 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Radiant energy 250/208.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795583 | Hubbard et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Richard F Hubbard (Burke, Virginia); Arne W Fliflet (Alexandria, Virginia); Jeffrey H Bowles (Burke, Virginia); David A Kidwell (Alexandria, Virginia); Melissa K. Hornstein (Washington, District of Columbia); Geoffrey B. Smith (Manassas, Virginia); David Lewis, III (Mountain View, California) |
ABSTRACT | A long-range active thermal imaging system includes an electromagnetic radiation source in the range of from about 10 GHz to about 500 GHz; a beam controller for receiving and retransmitting the electromagnetic radiation in a desired direction toward and onto a surface of a target, thereby heating the target and producing an infrared radiation emission from the target surface; and an infrared imager, e.g. an infrared camera coupled to a processor and display, for receiving the target's infrared radiation emission and generating a thermal image of the target. The radiation source may be selected such that the radiation penetrates into the target to provide a thermal signature, e.g. from subsurface features or objects. The thermal signature exhibits rapid changes that can be monitored in real time. This may allow surface or subsurface details or objects to be detected that would not otherwise be apparent. |
FILED | Friday, October 06, 2006 |
APPL NO | 11/539380 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/338.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795596 | Chowdhury |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Alcatel-Lucent USA Inc. (Murray Hill, New Jersey) |
INVENTOR(S) | Aref Chowdhury (Berkeley Heights, New Jersey) |
ABSTRACT | System including electromagnetic radiation source and electromagnetic radiation detector. Electromagnetic radiation source is configured to excite, with electromagnetic radiation having first source frequency, object configured for suppressing responsive emission of electromagnetic radiation having first source frequency. Electromagnetic radiation detector is configured to receive responsive emission of electromagnetic radiation from object. System is configured to detect presence of object. Method includes exciting, with electromagnetic radiation having first source frequency, object configured for suppressing responsive emission of electromagnetic radiation having first source frequency. Method includes receiving responsive emission of electromagnetic radiation from object and utilizing responsive emission to detect presence of object. |
FILED | Thursday, January 03, 2008 |
APPL NO | 12/006529 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/393 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795602 | Leonard et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Polaris Industries Inc. (Medina, Minnesota) |
INVENTOR(S) | Joshua J. Leonard (North Branch, Minnesota); Richard Raymond Maki (North Branch, Minnesota); Eric Bjerketvedt (North Branch, Minnesota); Mitchell D. Johnson (Roseau, Minnesota); Bradley Robert Morisch (Lindstrom, Minnesota); Brian D. Krosschell (Chisago City, Minnesota); Louis J. Brady (Wyoming, Minnesota); James Bergman (Oslo, Minnesota); Larry Holter (Alvarado, Minnesota); Richard Nelson (Oslo, Minnesota); Lionel Hoff (Oslo, Minnesota); Doug Moman (Warren, Minnesota); Michael D. Schneider (Dalbo, Minnesota) |
ABSTRACT | A utility vehicle (100) with ergonomic, safety, and maintenance features is disclosed. The ergonomic, safety, and maintenance features enhance the utility of the vehicle. |
FILED | Monday, March 17, 2008 |
APPL NO | 12/092191 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/495.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795609 | Huffaker et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Diana L. Huffaker (Albuquerque, New Mexico); Noppadon Nuntawong (Albuquerque, New Mexico) |
ABSTRACT | Embodiments provide a quantum dot active structure and a methodology for its fabrication. The quantum dot active structure includes a substrate, a plurality of alternating regions of a quantum dot active region and a strain-compensation region, and a cap layer. The strain-compensation region is formed to eliminate the compressive strain of an adjacent quantum dot active region, thus allowing quantum dot active regions to be densely-stacked. The densely-stacked quantum dot active region provides increased optical modal gain for semiconductor light emitting devices such as edge emitting lasers, vertical cavity lasers, detectors, micro-cavity emitters, optical amplifiers or modulators. |
FILED | Monday, August 07, 2006 |
APPL NO | 11/462777 |
ART UNIT | 2822 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/14 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795708 | Katti |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Romney R. Katti (Shorewood, Minnesota) |
ABSTRACT | A magnetic shield is presented. The shield may be used to protect a microelectronic device from stray magnetic fields. The shield includes at least two layers. A first layer includes a magnetic material that may be used to block DC magnetic fields. A second layer includes a conductive material that may be used to block AC magnetic fields. Depending on the type of material that the first and second layers include, a third layer may be inserted in between the first and second layers. The third layer may include a non-conductive material that may be used to ensure that separate eddy current regions form in the first and second layers. |
FILED | Friday, June 02, 2006 |
APPL NO | 11/445874 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/659 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795900 | Lesea et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Xilinx, Inc. (San Jose, California) |
INVENTOR(S) | Austin H. Lesea (Los Gatos, California); Tan C. Hoang (New Almaden, California) |
ABSTRACT | An integrated circuit has a memory array with a four-plex of SEU-hardened memory cells. Each of the SEU-hardened memory cells has an orientation different from each of the other SEU-hardened memory cells in the four-plex, and each of the SEU-hardened memory cells has a different critical ion track. Providing a four-plex of SEU-hardened memory cells, each with a different critical ion track, reduces the probability of a single ion upsetting adjacent memory cells. |
FILED | Tuesday, June 16, 2009 |
APPL NO | 12/485241 |
ART UNIT | 2819 — Semiconductors/Memory |
CURRENT CPC | Electronic digital logic circuitry 326/9 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796103 | Doane et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Kent Displays Incorporated (Kent, Ohio) |
INVENTOR(S) | J. William Doane (Kent, Ohio); Asad A. Khan (Kent, Ohio); Irina Shiyanovskaya (Stow, Ohio); Albert Green (Springfield, Virginia) |
ABSTRACT | The present invention relates to a display film that may be transferred by lamination or otherwise onto a substrate. The display film is formed of a stack of layers that can include different types, arrangements, and functionality within the stack depending upon factors including the characteristics of the substrate (e.g., upper or lower, transparent or opaque, substrates) and addressing of the display (e.g., active or passive matrix, electrical or optical addressing). The layers of the stacked display film include one or more electrode layers and one or more liquid crystal layers and, in addition, may include various combinations of an adhesive layer, preparation layer, casting layer, light absorbing layer, insulation layers, and protective layers. The liquid crystal layer can include cholesteric or other liquid crystal material. The liquid crystal layer can be a dispersion of liquid crystal in a polymer matrix formed by a variety of techniques. The display film may interact with components mounted on or laminated to the substrate, including a solar cell, active matrix backplane and electrodes. The display film may be mounted onto flexible or drapable substrates such as fabric and can itself be drapable. Thus, the invention offers substantial flexibility in fabrication and design that has not been previously possible in the display industry. |
FILED | Friday, January 28, 2005 |
APPL NO | 10/587591 |
ART UNIT | 2629 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Computer graphics processing and selective visual display systems 345/87 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796262 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Nomadics, Inc. (Stillwater, Oklahoma) |
INVENTOR(S) | Shaopeng Wang (Stillwater, Oklahoma); Akhilesh Ramachandran (Stillwater, Oklahoma); Edward T Knobbe (Stillwater, Oklahoma); Frederick Gorr Johnson (Ellicott City, Maryland); Brent Everett Little (Glen Head, New York); David Wesley Goad (Stillwater, Oklahoma) |
ABSTRACT | The current invention provides methods for detecting trace analytes in solution or suspension using coupled micro-ring resonators. The methods of the current invention determine the presence and concentration of the target analytes in real time by exposing the micro-ring resonator to the analyte and determining the resulting rate of change of resonance wavelength experienced by a sensing micro-ring resonator as compared to a reference micro-ring resonator. |
FILED | Thursday, May 31, 2007 |
APPL NO | 11/809867 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/436 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796320 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Yang Yang (Los Angeles, California); Hsing-En Elbert Wu (Santa Monica, California) |
ABSTRACT | An electrode for an electro-optic device has a wetting layer of electrically conductive material formed on a substrate. A second layer of electrically conductive material is formed on the wetting layer of electrically conductive material. The wetting layer has a first wetting ability with respect to a surface of the substrate and the second layer has a second wetting ability with respect to the surface of said substrate. The first wetting ability is different from the second wetting ability and the wetting layer acts to alter an optical property of the electrode due to the wetting ability of the wetting layer on the surface of the substrate. |
FILED | Monday, October 24, 2005 |
APPL NO | 11/664701 |
ART UNIT | 2873 — Optics |
CURRENT CPC | Optical: Systems and elements 359/245 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796326 | Shay et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Thomas M. Shay (Albuquerque, New Mexico); Craig A. Robin (Albuquerque, New Mexico); Athanasios Gavrielides (Albuquerque, New Mexico); Justin Spring (Fairborn, Ohio) |
ABSTRACT | A method and system whereby a narrow linewidth coherent laser source when transmitted as a plurality of output signals and subsequently detected at a distance appears to produce the uniform illumination characteristics of an incoherent source thereby suppressing laser speckle and environmentally induced scintillation effects. A master oscillator source is split into N signals, each of which is independently phase modulated by frequencies designed to minimize a derived apparent incoherence factor. The signals are then either directed to an object to be illuminated so that they overlap at the object or first recombined and directed to the object. |
FILED | Monday, January 22, 2007 |
APPL NO | 11/625372 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optical: Systems and elements 359/349 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796334 | Bochove |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Erik J. Bochove (Corrales, New Mexico) |
ABSTRACT | A plurality of optically isotropic, parallel dielectric plates of uniform thickness, mutually separated by gaps having a uniform width. The plates are connected by spacers located in the gaps. The gaps are either filled with a gas or evacuated. The plate thickness is on the order of one-half of the wavelength of incident radiation traveling within the medium filling the gaps. Each plate is composed of a transparent material characterized by its index of refraction. The stack of plates should include at least fifteen plates. This abstract is provided to comply with the rules requiring an abstract, and is intended to allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR §1.72(b). |
FILED | Tuesday, September 25, 2007 |
APPL NO | 11/860717 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/584 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796371 | Xie et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Jun Xie (Pasadena, California); Jason Shih (Yorba Linda, California); Yu-Chong Tai (Pasadena, California) |
ABSTRACT | A micro fluidic device and method for capacitive sensing. The device includes a fluid channel including an inlet at a first end and an outlet at a second end, a cavity region coupled to the fluid channel, and a polymer based membrane coupled between the fluid channel and the cavity region. Additionally, the device includes a first capacitor electrode coupled to the membrane, a second capacitor electrode coupled to the cavity region and physically separated from the first capacitor electrode by at least the cavity region, and an electrical power source coupled between the first capacitor electrode and the second capacitor electrode and causing an electric field at least within the cavity region. The polymer based membrane includes a polymer. |
FILED | Monday, July 30, 2007 |
APPL NO | 11/830581 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/283.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796384 | Irving et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Eric Irving (Albuquerque, New Mexico); Charles Pinney (Albuquerque, New Mexico); Tom Hensley (Albuquerque, New Mexico) |
ABSTRACT | In a system for housing electronics cards, methods and systems for cooling the electronics cards are presented. Each electronics card preferably contains heat-producing electronics and a heat sink, and is preferably placed within a card guide of the chassis and secured into position with a clamping device. At least one of the heat sink, the card guide, the clamping device, and a cold wall of the chassis are used to facilitate the conduction cooling of the heat-producing electronics. Furthermore, a clamping device may rigidly secure a card into position, thus reducing the impact of vibrations (including shock) on the card. Additionally, an air flow further cools the electronics cards, the card guides, and/or the cold wall. |
FILED | Wednesday, August 27, 2008 |
APPL NO | 12/199416 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/694 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796517 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Minghua Chen (Albany, California); Avideh Zakhor (Berkeley, California) |
ABSTRACT | Multiple TRFC connections transport streaming data through a wireless channel, and the difference between measured round trip times of packets and minimum round trip time is used to adjust the number of TFRC connections to fully utilize bandwidth through the wireless channel. |
FILED | Tuesday, June 07, 2005 |
APPL NO | 11/147788 |
ART UNIT | 2474 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/235 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796809 | Carder et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Kendall L. Carder (St. Petersburg, Florida); Phillip N. Reinersman (Tampa, Florida) |
ABSTRACT | A remote 3-D imaging system which uses a novel angular relationship to establish the relationship of the image features to the system, which is displayed by virtue of calculations. In addition to static surfaces, moving surfaces may be studied and corrections due to turbidity and platform position are also easily compensated for. A pre-test module is also included which predicts and has the ability to re-adjust the instrumentation to the test conditions as predicted by a hybrid Monte Carlo model. The instant system may also contain a plurality of sensing systems based on light, including traditional reflective or elastic scattering and novel fluorescent or non elastic scattering still and video imaging systems, including time-gated systems. |
FILED | Wednesday, December 15, 2004 |
APPL NO | 10/905098 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/154 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796829 | Nguyen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Lam Huy Nguyen (Laurel, Maryland); Jeffrey P. Sichina (Ocean View, Delaware) |
ABSTRACT | A method and system for generating images from projection data; a preferred embodiment comprising inputting projection data from at least one receiving element; generating a first aperture or array of data points containing positional and signal data; arbitrarily and/or randomly removing data points from the first array to form a series of subarrays comprising different sets of data points; generating preliminary images from the subarrays; comparing the corresponding image pixels from two preliminary images to determine for each pixel location the lesser or equal pixel values; forming a merged image from the lesser or equal pixel values; and repeating the comparison of corresponding image pixels of another preliminary image to the merged image to determine the lesser or equal pixel values until a merged image of the desired quality is obtained. A preferred embodiment of the system may comprise at least one processor, comparator and/or image generator. |
FILED | Wednesday, December 10, 2008 |
APPL NO | 12/331888 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Image analysis 382/260 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797040 | Pesaran et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Bijan Pesaran (Los Angeles, California); Richard A. Andersen (La Canada, California) |
ABSTRACT | Prosthetic devices, methods and systems are disclosed. Eye position and/or neural activity of a primate are recorded and combined. The combination signal is compared with a predetermined signal. The result of the comparison step is used to actuate the prosthetic device. |
FILED | Thursday, December 15, 2005 |
APPL NO | 11/300965 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/545 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797130 | Silberg et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Eric J. Silberg (Potomac, Maryland); Phong Hua Nguyen (Reston, Virginia); Daniel P. Everson (Silver Spring, Maryland); Naipei P. Bi (Gaithersburg, Maryland) |
ABSTRACT | According to typical inventive practice, a baseline describing a statistical distribution is established for a set of historical occurrences of an event. Comparison is made between the baseline and at least one current occurrence of the same event. Any current occurrence that is anomalous vis-à-vis the baseline is considered a possible leading indicator. According to some inventive embodiments of graphical presentation of such comparison, at least one graphical baseline comparative display component is rendered that includes a “bar” (describing a historical statistical distribution with respect to a criterion pertaining to occurrence of an event) and a “slider” (describing one or more current occurrences of the event). The bar includes at least one band representing a statistical mean range, and at least one band representing a statistical outlier range. Situation of the slider along the bar indicates whether and to what extent the current occurrence(s) is/are anomalous vis-à-vis the baseline. |
FILED | Thursday, December 20, 2007 |
APPL NO | 12/006754 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/179 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797148 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Stanley Chen (Port Jefferson, New York); Yuqing Gao (Mount Kisco, New York); Bowen Zhou (Ossining, New York) |
ABSTRACT | A phrase-based translation system and method includes a statistically integrated phrase lattice (SIPL) (H) which represents an entire translational model. An input (I) is translated by determining a best path through an entire lattice (S) by performing an efficient composition operation between the input and the SIPL. The efficient composition operation is performed by a multiple level search where each operand in the efficient composition operation represents a different search level. |
FILED | Wednesday, June 04, 2008 |
APPL NO | 12/132791 |
ART UNIT | 2626 — Selective Visual Display Systems |
CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797156 | Preuss et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
INVENTOR(S) | Robert David Preuss (Sagamore Beach, Massachusetts); Darren Ross Fabbri (Arlington, Massachusetts); Daniel Ramsay Cruthirds (Cambridge, Massachusetts) |
ABSTRACT | Presented herein are systems and methods for generating an adaptive noise codebook for use with electronic speech systems. The noise codebook includes a plurality of entries which may be updated based on environmental noise sounds. The speech system includes a speech codebook and the adaptive noise codebook. The system identifies speech sounds in an audio signal using the speech and noise codebooks. |
FILED | Wednesday, February 15, 2006 |
APPL NO | 11/355777 |
ART UNIT | 2626 — Selective Visual Display Systems |
CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/233 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797329 | Lujan Moreno et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Oracle America Inc. (Redwood City, California) |
INVENTOR(S) | Miguel Angel Lujan Moreno (Mountain View, California); Phyllis E. Gustafson (Pleasanton, California); Michael H. Paleczny (San Jose, California); Christopher A. Vick (San Jose, California); Jay R. Freeman (Palo Alto, California); Olaf Manczak (Hayward, California) |
ABSTRACT | A method for committing memory transactions in an application that includes executing a plurality of sections of the application in parallel, logging a plurality of memory transactions that occur while executing the plurality of sections to obtain a plurality of logs and a plurality of temporary results, wherein the plurality of memory transactions that includes a plurality of writes to at least one memory location, comparing the plurality of logs to identify an optimal list of writes from the plurality of writes, and committing memory transactions corresponding to a subset of the plurality of temporary results, wherein the subset of the plurality of temporary results is identified by the optimal list of writes. |
FILED | Friday, June 09, 2006 |
APPL NO | 11/450763 |
ART UNIT | 2158 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/758 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797367 | Gelvin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | David C. Gelvin (Escondido, California); Lewis D. Girod (Los Angeles, California); William J. Kaiser (Los Angeles, California); William M. Merrill (Los Angeles, California); Fredric Newberg (San Diego, California); Gregory J. Pottie (Los Angeles, California); Anton I. Sipos (Los Angeles, California); Sandeep Vardhan (Walnut, California) |
ABSTRACT | The Wireless Integrated Network Sensor Next Generation (WINS NG) nodes provide distributed network and Internet access to sensors, controls, and processors that are deeply embedded in equipment, facilities, and the environment. The WINS NG network is a new monitoring and control capability for applications in transportation, manufacturing, health care, environmental monitoring, and safety and security. The WINS NG nodes combine microsensor technology, low power distributed signal processing, low power computation, and low power, low cost wireless and/or wired networking capability in a compact system. The WINS NG networks provide sensing, local control, remote reconfigurability, and embedded intelligent systems in structures, materials, and environments. |
FILED | Wednesday, October 04, 2000 |
APPL NO | 09/684387 |
ART UNIT | 2451 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797588 | Arimilli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Robert S. Blackmore (Poughkeepsie, New York); Chulho Kim (Poughkeepsie, New York); Hanhong Xue (Poughkeepsie, New York) |
ABSTRACT | In a global shared memory (GSM) environment, an initiating task at a first node with a host fabric interface (HFI) uses epochs to provide reliability of transmission of packets via a network fabric to a target task. The HFI generates a packet for the initiating task addressed to the target task, and automatically inserts a current epoch of the initiating task into the packet. A copy of the current epoch is maintained by the target task, which accepts for processing only packets having the correct epoch, unless the packet is tagged for guaranteed-once delivery. When a packet delivery is accepted, the target task sends a notification to the initiating task. If the initiating task does not receive the notification of delivery for the issued packet, the initiating task updates the epoch at both the target node and the initiating node and re-transmits the packet. |
FILED | Friday, February 01, 2008 |
APPL NO | 12/024637 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/51 |
VIEW PATENT | @ USPTO: Full Text PDF |
US D623717 | Saur |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Thomas W. Saur (Dearborn, Michigan) |
ABSTRACT | |
FILED | Thursday, June 25, 2009 |
APPL NO | 29/339161 |
ART UNIT | 2914 — Design |
CURRENT CPC | Arms, pyrotechnics, hunting and fishing equipment D22/108 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07793763 | Zhu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
INVENTOR(S) | Weidong Zhu (Elridge, Maryland); Yan Chen (Baltimore, Maryland) |
ABSTRACT | A vibration damped elevator system is provided that includes a damper or dampers attached to the elevator cable. The damping coefficients of the damper or dampers are chosen to provide optimum dissipation of the vibratory energy in the elevator cable. A method of determining the optimum placement of the damper or dampers and their respective damping coefficients is also provided. |
FILED | Monday, May 08, 2006 |
APPL NO | 11/429243 |
ART UNIT | 3654 — Material and Article Handling |
CURRENT CPC | Elevator, industrial lift truck, or stationary lift for vehicle 187/411 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794230 | Lakin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
INVENTOR(S) | William D. Lakin (Johnson, Vermont); Scott A. Stevens (Erie, Pennsylvania) |
ABSTRACT | A system and method of modeling a circulatory system including a regulatory mechanism parameter. In one embodiment, a regulatory mechanism parameter in a lumped parameter model is represented as a logistic function. In another embodiment, the circulatory system model includes a compliant vessel, the model having a parameter representing a change in pressure due to contraction of smooth muscles of a wall of the vessel. |
FILED | Thursday, March 23, 2006 |
APPL NO | 11/387397 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Education and demonstration 434/270 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794553 | Duan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Gang Duan (Chandler, Arizona); William L. Johnson (Pasadena, California); Aaron Wiest (Los Angeles, California) |
ABSTRACT | High strength, thermoplastically processable (TPF) amorphous alloys composed of Beryllium and at least one ETM and at least one LTM, as well as methods of processing such alloys are provided. The TPF alloys of the invention demonstrate good glass forming ability, low viscosity in the supercooled liquid region (SCLR), a low processing temperature, and a long processing time at that temperature before crystallization. |
FILED | Friday, December 07, 2007 |
APPL NO | 11/952694 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Metal treatment 148/403 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794557 | Hui et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Inframat Corporation (Farmington, Connecticut) |
INVENTOR(S) | Shiqiang Hui (Vancouver, Canada); Yide Zhang (Storrs, Connecticut); Danny Xiao (Willington, Connecticut); Mingzhong Wu (Fort Collins, Colorado) |
ABSTRACT | A precursor tape casting method is one in which chemical precursors are converted into a final chemical phase from green tapes to products. Because chemical precursors are employed rather than the final powder materials, sintering is not required to form the material. Lower annealing temperatures instead of high temperature sintering allow the formation of grains of about 1 to about 100 nanometers in the final material. In addition, when the final material is a magnetic/insulator composite, improved magnetic properties may be obtained. |
FILED | Friday, June 10, 2005 |
APPL NO | 11/150592 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/89.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794584 | Chodavarapu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
INVENTOR(S) | Vamsy P. Chodavarapu (Verdun, Canada); Alexander N. Cartwright (Williamsville, New York); Albert H. Titus (Buffalo, New York); Rachel M. Bukowski (Buffalo, New York); Frank V. Bright (Williamsville, New York) |
ABSTRACT | pH-change sensors and related methods are disclosed. One such sensor may have a first ion-sensitive transistor-operational-transconductance-amplifier (the “first IOTA”) and a second ion-sensitive transistor-operational-transconductance-amplifier (the “second IOTA”). Each IOTA may have an ion-sensitive transistor, a load transistor, and an output. In each IOTA, the drain region of the ion-sensitive transistor may be connected to the drain region of the load transistor. A differential sensor may be connected to the IOTAs, and an output from the differential sensor may indicate a voltage difference between the IOTA outputs. The output from the differential sensor may be used to provide an indication of a change in pH. |
FILED | Thursday, October 12, 2006 |
APPL NO | 11/548995 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/777.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794682 | Diener et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
INVENTOR(S) | Michael D. Diener (Boulder, Colorado); James W. Raebiger (Golden, Colorado); Robert D. Bolskar (Arvada, Colorado); John M. Alford (Lakewood, Colorado) |
ABSTRACT | A method of extracting fullerenes from a carbon matrix in which they are produced. The method is applicable to both fullerenes that exhibit greater than 0.1 mg/ml solubility in toluene and to fullerenes that are essentially insoluble in toluene, i.e., those exhibiting less than or equal to 0.1 mg/ml solubility. The method disclosed herein extracts more of the soluble fullerenes from the carbon matrix than extraction conducted by solely contacting with solvent. A method is also provided for creating salts of the extracted fullerenes. |
FILED | Tuesday, February 28, 2006 |
APPL NO | 11/364808 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry of inorganic compounds 423/445.B00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794742 | Giachelli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Cecilia Maria Giachelli (Mill Creek, Washington); Benjamin Leo Beckstead (Seattle, Washington) |
ABSTRACT | In one aspect, the present invention provides a biomaterial having at least one biocompatible surface. The biocompatible surface comprises a plurality of immobilized Notch ligand molecules, wherein the plurality of immobilized Notch ligand molecules are capable of promoting differentiation in one or more epithelial cells. In another aspect, the present invention provides an implantable medical device comprising a layer of a biomaterial. Another aspect of the invention provides methods for promoting epithelial cell differentiation. The methods of this aspect of the invention include the step of contacting one or more epithelial cells with a biomaterial comprising an amount of immobilized Notch ligand molecules sufficient to promote differentiation in the one or more epithelial cells. |
FILED | Tuesday, February 08, 2005 |
APPL NO | 11/054369 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/426 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794797 | Vasenkov |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
INVENTOR(S) | Aleksey V. Vasenkov (Huntsville, Alabama) |
ABSTRACT | The present invention is a catalytic chemical vapor deposition method and apparatus for synthesizing carbon nanotubes and/or carbon nanofibers (CNTs) on a substrate by selectively heating a catalyst for CNT synthesis on or near the surface of the substrate. Selective heating of the catalyst is achieved using an exothermic oxidation reaction on the surface of the catalyst. Selective heating of the catalyst prevents heating of the substrate and enables the synthesis of CNTs on temperature sensitive substrates. |
FILED | Tuesday, January 30, 2007 |
APPL NO | 11/668741 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating processes 427/450 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794833 | Balkus, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Kenneth J. Balkus, Jr. (The Colony, Texas); John P. Ferraris (Coppell, Texas); Sudha Madhugiri (Richardson, Texas); Ashley S. Scott (Grove City, Ohio) |
ABSTRACT | Electrospun fibers comprising mesoporous molecular sieve materials are described. In an aspect of the invention, fibers are electrospun from a conducting solution to which a high voltage electric current is applied. The apparatus includes in one aspect one or more conducting solution introduction devices for providing a quantity of conducting solution, said conducting solution introduction devices being electrically charged thereby establishing an electric field between said conducting solution introduction devices and a target, and means for controlling the flow characteristics of conducting solution from said one or more conducting solution introduction devices. |
FILED | Friday, June 20, 2003 |
APPL NO | 10/601102 |
ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/364 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794862 | Wojtowicz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Advanced Fuel Research, Inc. (East Hartford, Connecticut) |
INVENTOR(S) | Marek A. Wojtowicz (Simsbury, Connecticut); Michael A. Serio (Sturbridge, Massachusetts); Erik Kroo (Glastonbury, Connecticut); Eric M. Suuberg (Barrington, Rhode Island) |
ABSTRACT | The method for generating a hydrogen-rich stream from hydrocarbon fuels, ultimately to produce hydrogen gas, involves the following two steps performed in a cyclic fashion: (1) pyrolysis of the hydrocarbon fuel to obtain a carbon-rich fraction and a hydrogen-rich fraction; and (2) oxidation of the carbon-rich fraction, or a portion of it, for heat generation. The method involves the following optional steps: (3) steam gasification of part of the carbon-rich fraction to produce additional amounts of hydrogen and carbon monoxide; (4) water-gas shift reaction to convert carbon monoxide to carbon dioxide with the simultaneous formation of additional amounts of hydrogen; and (5) steam reforming of light hydrocarbons that may be produced in step (1) to produce more hydrogen and carbon monoxide. |
FILED | Thursday, March 20, 2008 |
APPL NO | 12/077654 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794931 | Breaker et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Ronald R. Breaker (Guilford, Connecticut); Ali Nahvi (New Haven, Connecticut); Narasimhan Sudarsan (New Haven, Connecticut); Margaret S. Ebert (Hopewell, New Jersey); Wade Winkler (New Haven, Connecticut); Jeffrey E. Barrick (New Haven, Connecticut); John K. Wickiser (New Haven, Connecticut) |
ABSTRACT | It has been discovered that certain natural mRNAs serve as metabolite-sensitive genetic switches wherein the RNA directly binds a small organic molecule. This binding process changes the conformation of the mRNA, which causes a change in gene expression by a variety of different mechanisms. Modified versions of these natural “riboswitches” (created by using various nucleic acid engineering strategies) can be employed as designer genetic switches that are controlled by specific effector compounds. Such effector compounds that activate a riboswitch are referred to herein as trigger molecules. The natural switches are targets for antibiotics and other small molecule therapies. In addition, the architecture of riboswitches allows actual pieces of the natural switches to be used to construct new non-immunogenic genetic control elements, for example the aptamer (molecular recognition) domain can be swapped with other non-natural aptamers (or otherwise modified) such that the new recognition domain causes genetic modulation with user-defined effector compounds. The changed switches become part of a therapy regimen—turning on, or off, or regulating protein synthesis. Newly constructed genetic regulation networks can be applied in such areas as living biosensors, metabolic engineering of organisms, and in advanced forms of gene therapy treatments. |
FILED | Monday, September 22, 2003 |
APPL NO | 10/669162 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794936 | Benner et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Steven Albert Benner (Gainesville, Florida); Albert Michael Sismour (Cambridge, Massachusetts) |
ABSTRACT | This invention relates to nucleoside, nucleotide, and oligonucleotide analogs that incorporate non-standard nucleobase analogs, those that present a pattern of hydrogen bonds to a paired nucleobase analog in a complementary strand that is different from the pattern presented by adenine, guanine, cytosine, and thymine. Most specifically, this invention discloses and claims processes for amplifying nucleic acid analogs containing non-standard nucleobases using polymerase chain reactions, and combinations of non-standard nucleobases, analogs of standard nucleotides, and enzymes that perform this amplification. Most specifically, this invention is for the use of 2-thiothymidine triphosphate (2-thioTTP) instead of thymidine triphosphate in a six letter polymerase chain reaction that includes 2′-deoxyadenosine triphosphate, 2′-deoxyguanosine triphosphate, 2′-deoxycytidine triphosphate, 2′-deoxy-iso-guanosine triphosphate, and 2′-deoxy-iso-cytidine triphosphate, as well as their forms that contain side chain modifications. Because of the size and hydrogen bonding properties of the sulfur unit in 2-thioT, 2-thioT does not mispair effectively with the minor tautomer of isoG. This permits the PCR amplification of a six letter artificially expanded genetic information system, we examined the relative rates of misincorporation of 2-thioTTP and TTP opposite isoG using affinity electrophoresis with a fidelity-per-round of ca. 98%. The analogous PCR employing TTP has a fidelity-per-round of only ca. 93%. Therefore, this invention represents the first example of a six letter artificial genetic system that is amplifiable by a thermostable polymerase, and capable of Darwinian evolution. |
FILED | Friday, September 29, 2006 |
APPL NO | 11/541295 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795007 | Abbott et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Brian H. Clare (Madison, Wisconsin); Paul J. Bertics (Oregon, Wisconsin) |
ABSTRACT | A method for differentiating between a post-translationally modified peptide and a peptide contained in a sample, comprising: (a) contacting the sample with a peptide attachment surface to create a peptidized surface, wherein the sample includes at least one functional group; (b) contacting the peptidized surface with a recognition reagent that selectively binds or forms a complex with the post-translationally modified peptide in the sample to provide an incubated surface; and (c) contacting a liquid crystal with the incubated surface and detecting presence of post-translationally modified peptide in the sample with the liquid crystal. |
FILED | Monday, June 20, 2005 |
APPL NO | 11/156911 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795397 | Lagarias et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | John Clark Lagarias (Davis, California); Amanda J. Fischer (Davis, California) |
ABSTRACT | This invention provides fluorescent adducts that emit in the far red and/or near infrared. In certain embodiments, the adducts comprise a mutant apoprotein and a bilin. |
FILED | Thursday, May 05, 2005 |
APPL NO | 11/123692 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/370 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795411 | Scholler et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
INVENTOR(S) | Nathalie Scholler (Seattle, Washington); Barbara Garvik (Seattle, Washington) |
ABSTRACT | The present invention provides compositions and methods for generating in vivo biotinylated, secreted recombinant polypeptides comprising recombinantly co-expressing in a yeast cell (a) a secreted recombinant polypeptide comprising a biotin accepting site; and (b) a biotin ligase fused to the golgi localization domain so that the biotin ligase is localized to the golgi of the yeast cell where it acts on the biotin-accepting site of the secreted polypeptide as it transits the secretory system. |
FILED | Wednesday, January 31, 2007 |
APPL NO | 11/669811 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Organic compounds 536/23.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795509 | Conkling et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Mark A. Conkling (Fuquay Varina, North Carolina); Wen Song (San Diego, California); Nandini Mendu (Durham, North Carolina) |
ABSTRACT | DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are provided. |
FILED | Wednesday, May 03, 2006 |
APPL NO | 11/416887 |
ART UNIT | 1638 — Organic Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/317.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796270 | Yelin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Dvir Yelin (Brookline, Massachusetts); Seok-Hyun Yun (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts); Guillermo J Tearney (Cambridge, Massachusetts) |
ABSTRACT | Exemplary systems and methods for generating data associated with at least one portion of a sample can be provided. For example, according to one exemplary embodiment of such systems and methods, it is possible to provide a particular radiation using at least one first arrangement. The particular radiation can include at least one first electro-magnetic radiation directed to at least one sample and at least one second electro-magnetic radiation directed to a reference arrangement. The first radiation and/or the second radiation can comprise a plurality of wavelengths. The first electro-magnetic radiation can be spectrally dispersed along at least one portion of the sample. The second electro-magnetic radiation measured at two or more different lengths of the reference arrangement with respect to the first arrangement. Data can be generated which is associated with the first and second electro-magnetic radiations obtained at the two different lengths using at least one second arrangement which comprises a spectrometer arrangement. |
FILED | Wednesday, January 10, 2007 |
APPL NO | 11/621694 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/456 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796371 | Xie et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Jun Xie (Pasadena, California); Jason Shih (Yorba Linda, California); Yu-Chong Tai (Pasadena, California) |
ABSTRACT | A micro fluidic device and method for capacitive sensing. The device includes a fluid channel including an inlet at a first end and an outlet at a second end, a cavity region coupled to the fluid channel, and a polymer based membrane coupled between the fluid channel and the cavity region. Additionally, the device includes a first capacitor electrode coupled to the membrane, a second capacitor electrode coupled to the cavity region and physically separated from the first capacitor electrode by at least the cavity region, and an electrical power source coupled between the first capacitor electrode and the second capacitor electrode and causing an electric field at least within the cavity region. The polymer based membrane includes a polymer. |
FILED | Monday, July 30, 2007 |
APPL NO | 11/830581 |
ART UNIT | 2831 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/283.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796517 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Minghua Chen (Albany, California); Avideh Zakhor (Berkeley, California) |
ABSTRACT | Multiple TRFC connections transport streaming data through a wireless channel, and the difference between measured round trip times of packets and minimum round trip time is used to adjust the number of TFRC connections to fully utilize bandwidth through the wireless channel. |
FILED | Tuesday, June 07, 2005 |
APPL NO | 11/147788 |
ART UNIT | 2474 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/235 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797757 | Degertekin |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Fahrettin Levent Degertekin (Atlanta, Georgia) |
ABSTRACT | An atomic force microscopy sensor includes a substrate, a cantilever beam and an electrostatic actuator. The cantilever beam has a proximal end and an opposite distal end. The proximal end is in a fixed relationship with the substrate and the cantilever beam is configured so that the distal end is in a moveable relationship with respect to the substrate. The electrostatic actuator includes a first electrode that is coupled to the cantilever beam adjacent to the proximal end and a spaced apart second electrode that is in a fixed relationship with the substrate. When an electrical potential is applied between the first electrode and the second electrode, the first electrode is drawn to the second electrode, thereby causing the distal end of the cantilever beam to move. |
FILED | Tuesday, August 14, 2007 |
APPL NO | 11/838547 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/7 |
VIEW PATENT | @ USPTO: Full Text PDF |
US RE41693 | Gust, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Arizona Board of Regents, Acting for and on Behalf of, Arizona State University (Tempe, Arizona) |
INVENTOR(S) | John D. Gust, Jr. (Mesa, Arizona); Ana L. Moore (Scottsdale, Arizona); Thomas Moore (Scottsdale, Arizona) |
ABSTRACT | Excitation of a triad artificial photosynthetic reaction center consisting of a porphyrin (P) convalently linked to a fullerene electron acceptor (C60) and a carotenoid secondary donor (C) leads to the formation of a long-lived C+-P-C60− charge-separated state via photoinduced electron transfer. This reaction occurs in a frozen organic glass down to at least 8 K. At 77 K, charge recombination of C*+-P-C60− occurs on the μs time scale, and yields solely the carotenoid triplet state. In the presence of a small (20 mT) static magnetic field, the lifetime of the charge-separated state is increased by 50%. This is ascribed to the effect of the magnetic field on interconversion of the singlet and triplet biradicals. At zero field, the initially formed singlet biradical state is in equilibrium with the three triplet biradical sublevels, and all four states have comparable populations. Decay to the carotenoid triplet only occurs from the three triplet sublevels. In the presence of the field, the S and T0 states are still rapidly interconverting, but the T+ and T− states are isolated from the other two due to the electronic Zeeman interaction, and are not significantly populated. Under these conditions, recombination to the triplet occurs only from T0, and the lifetime of the charge-separated state increases. This effect can be used as the basis for a magnetically controlled optical or optoelectronic switch (e.g. AND gate). |
FILED | Thursday, November 30, 2006 |
APPL NO | 11/565506 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical waveguides 385/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07793722 | Vinegar et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
INVENTOR(S) | Harold J. Vinegar (Bellaire, Texas); Christopher Kelvin Harris (Houston, Texas); Stanley Leroy Mason (Allen, Texas) |
ABSTRACT | Systems, methods, and heaters for treating a subsurface formation are described herein. At least one system for electrically insulating an overburden portion of a heater wellbore is described. The system may include a heater wellbore located in a subsurface formation and an electrically insulating casing located in the overburden portion of the heater wellbore. The casing may include at least one non-ferromagnetic material such that ferromagnetic effects are inhibited in the casing. |
FILED | Friday, April 20, 2007 |
APPL NO | 11/788871 |
ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Wells 166/302 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794170 | Weil et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | K. Scott Weil (Richland, Washington); John S. Hardy (Richland, Washington) |
ABSTRACT | A joint for use in electrochemical devices, such as solid oxide fuel cells (SOFCs), oxygen separators, and hydrogen separators, that will maintain a hermetic seal at operating temperatures of greater than 600° C., despite repeated thermal cycling excess of 600° C. in a hostile operating environment where one side of the joint is continuously exposed to an oxidizing atmosphere and the other side is continuously exposed to a wet reducing gas. The joint is formed of a metal part, a ceramic part, and a flexible gasket. The flexible gasket is metal, but is thinner and more flexible than the metal part. As the joint is heated and cooled, the flexible gasket is configured to flex in response to changes in the relative size of the metal part and the ceramic part brought about by differences in the coefficient of thermal expansion of the metal part and the ceramic part, such that substantially all of the tension created by the differences in the expansion and contraction of the ceramic and metal parts is absorbed and dissipated by flexing the flexible gasket. |
FILED | Friday, April 22, 2005 |
APPL NO | 11/112122 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Joints and connections 43/50 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794394 | Frangioni |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
INVENTOR(S) | John V. Frangioni (Wayland, Massachusetts) |
ABSTRACT | An imaging device captures both a visible light image and a diagnostic image, the diagnostic image corresponding to emissions from an imaging medium within the object. The visible light image (which may be color or grayscale) and the diagnostic image may be superimposed to display regions of diagnostic significance within a visible light image. A number of imaging media may be used according to an intended application for the imaging device, and an imaging medium may have wavelengths above, below, or within the visible light spectrum. The devices described herein may be advantageously packaged within a single integrated device or other solid state device, and/or employed in an integrated, single-camera medical imaging system, as well as many non-medical imaging systems that would benefit from simultaneous capture of visible-light wavelength images along with images at other wavelengths. |
FILED | Thursday, May 22, 2003 |
APPL NO | 10/517280 |
ART UNIT | 3768 — Amusement and Education Devices |
CURRENT CPC | Surgery 6/160 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794894 | Chou et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Yeong-Shyung Chou (Richland, Washington); Kerry D. Meinhardt (Kennewick, Washington); Jeffry W. Stevenson (Richland, Washington) |
ABSTRACT | Multi-layer seals are provided that find advantageous use for reducing leakage of gases between adjacent components of electrochemical devices. Multi-layer seals of the invention include a gasket body defining first and second opposing surfaces and a compliant interlayer positioned adjacent each of the first and second surfaces. Also provided are methods for making and using the multi-layer seals, and electrochemical devices including said seals. |
FILED | Friday, April 13, 2007 |
APPL NO | 11/787053 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/509 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794938 | McBride et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Mary Teresa McBride (Brentwood, California); Thomas Richard Slezak (Livermore, California); Sharon Lee Messenger (Kensington, California) |
ABSTRACT | Described are kits and methods useful for detection of seven agricultural pathogens (BPSV; BHV; BVD; FMDV; BTV; SVD; and VESV) in a sample. Genomic sequence information from 7 agricultural pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample. |
FILED | Friday, January 12, 2007 |
APPL NO | 11/652841 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794978 | Chin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Jason W. Chin (Cambridge, United Kingdom); T. Ashton Cropp (Bethesda, Maryland); J. Christopher Anderson (San Francisco, California); Peter G. Schultz (La Jolla, California) |
ABSTRACT | This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. |
FILED | Friday, October 26, 2007 |
APPL NO | 11/978172 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795460 | Elliott |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
INVENTOR(S) | Brian Elliott (Wheat Ridge, Colorado) |
ABSTRACT | Methods of making alkyl esters are described herein. The methods are capable of using raw, unprocessed, low-cost feedstocks and waste grease. Generally, the method involves converting a glyceride source to a fatty acid composition and esterifying the fatty acid composition to make alkyl esters. In an embodiment, a method of making alkyl esters comprises providing a glyceride source. The method further comprises converting the glyceride source to a fatty acid composition comprising free fatty acids and less than about 1% glyceride by mass. Moreover, the method comprises esterifying the fatty acid composition in the presence of a solid acid catalyst at a temperature ranging firm about 70° C. to about 120° C. to produce alkyl esters, such that at least 85% of the free fatty acids are converted to alkyl esters. The method also incorporates the use of packed bed reactors for glyceride conversion and/or fatty acid esterification to make alkyl esters. |
FILED | Friday, May 05, 2006 |
APPL NO | 11/381924 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 554/167 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795595 | Reber et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Edward L. Reber (Idaho Falls, Idaho); Kenneth W. Rohde (Idaho Falls, Idaho); Larry G. Blackwood (Bozeman, Montana) |
ABSTRACT | A method for calibrating acquired spectra for use in spectral analysis includes performing Gaussian peak fitting to spectra acquired by a plurality of NaI detectors to define peak regions. A Na and annihilation doublet may be located among the peak regions. A predetermined energy level may be applied to one of the peaks in the doublet and a location of a hydrogen peak may be predicted based on the location of at least one of the peaks of the doublet. Control systems for calibrating spectra are also disclosed. |
FILED | Friday, January 23, 2009 |
APPL NO | 12/358883 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/390.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795770 | Romero et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Louis Romero (Albuquerque, New Mexico); Todd Christenson (Albuquerque, New Mexico); Eugene A. Aronson (Albuquerque, New Mexico) |
ABSTRACT | Stable levitation of an object in an alternating magnetic field can be achieved by eliminating coupling between the rotational and translational forces acting on the object. Stable levitation can also be achieved by varying the coupling between the rotational and translational forces acting on the object, while maintaining one or more of the rotational and translational forces steady in time. |
FILED | Wednesday, March 25, 2009 |
APPL NO | 12/411038 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/90.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796028 | Kotter et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Dale K. Kotter (Shelley, Idaho); David F. Spencer (Idaho Falls, Idaho); Lyle G. Roybal (Idaho Falls, Idaho); David T. Rohrbaugh (Idaho Falls, Idaho) |
ABSTRACT | Circuitry for detecting magnetic fields includes a first magnetoresistive sensor and a second magnetoresistive sensor configured to form a gradiometer. The circuitry includes a digital signal processor and a first feedback loop coupled between the first magnetoresistive sensor and the digital signal processor. A second feedback loop which is discrete from the first feedback loop is coupled between the second magnetoresistive sensor and the digital signal processor. |
FILED | Tuesday, August 01, 2006 |
APPL NO | 11/461515 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/539.220 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796388 | Wiles et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Randy H. Wiles (Powell, Tennessee); Andrew A. Wereszczak (Oak Ridge, Tennessee); Curtis W. Ayers (Kingston, Tennessee); Kirk T. Lowe (Knoxville, Tennessee) |
ABSTRACT | The disclosure describes directly cooling a three-dimensional, direct metallization (DM) layer in a power electronics device. To enable sufficient cooling, coolant flow channels are formed within the ceramic substrate. The direct metallization layer (typically copper) may be bonded to the ceramic substrate, and semiconductor chips (such as IGBT and diodes) may be soldered or sintered onto the direct metallization layer to form a power electronics module. Multiple modules may be attached to cooling headers that provide in-flow and out-flow of coolant through the channels in the ceramic substrate. The modules and cooling header assembly are preferably sized to fit inside the core of a toroidal shaped capacitor. |
FILED | Monday, March 09, 2009 |
APPL NO | 12/400081 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/699 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796527 | Archer et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Mark G. Megerian (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
ABSTRACT | Computer hardware fault administration carried out in a parallel computer, where the parallel computer includes a plurality of compute nodes. The compute nodes are coupled for data communications by at least two independent data communications networks, where each data communications network includes data communications links connected to the compute nodes. Typical embodiments carry out hardware fault administration by identifying a location of a defective link in the first data communications network of the parallel computer and routing communications data around the defective link through the second data communications network of the parallel computer. |
FILED | Thursday, April 13, 2006 |
APPL NO | 11/279579 |
ART UNIT | 2473 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/242 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796983 | Pao et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Hsueh-Yuan Pao (San Jose, California); Steven L. Dvorak (Tucson, Arizona) |
ABSTRACT | A physics-based statistical model and simulation/modeling method and system of electromagnetic wave propagation (wireless communication) in urban environments. In particular, the model is a computationally efficient close-formed parametric model of RF propagation in an urban environment which is extracted from a physics-based statistical wireless channel simulation method and system. The simulation divides the complex urban environment into a network of interconnected urban canyon waveguides which can be analyzed individually; calculates spectral coefficients of modal fields in the waveguides excited by the propagation using a database of statistical impedance boundary conditions which incorporates the complexity of building walls in the propagation model; determines statistical parameters of the calculated modal fields; and determines a parametric propagation model based on the statistical parameters of the calculated modal fields from which predictions of communications capability may be made. |
FILED | Thursday, April 27, 2006 |
APPL NO | 11/414054 |
ART UNIT | 2617 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Telecommunications 455/423 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797503 | Bellofatto et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Ralph E. Bellofatto (Ridgefield, Connecticut); Alan G. Gara (Mount Kisco, New York); Mark E. Giampapa (Irvington, New York); Martin Ohmacht (Yorktown Heights, New York) |
ABSTRACT | A memory system and method for providing atomic memory-based counter operations to operating systems and applications that make most efficient use of counter-backing memory and virtual and physical address space, while simplifying operating system memory management, and enabling the counter-backing memory to be used for purposes other than counter-backing storage when desired. The encoding and address decoding enabled by the invention provides all this functionality through a combination of software and hardware. |
FILED | Tuesday, June 26, 2007 |
APPL NO | 11/768812 |
ART UNIT | 2186 — Computer Architecture and I/O |
CURRENT CPC | Electrical computers and digital processing systems: Memory 711/163 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07794601 | Lima et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Isabel M. Lima (Mandeville, Louisiana); Wayne E. Marshall (Corvallis, Oregon) |
ABSTRACT | Chars may be produced by carbonization or pyrolysis of poultry manure. Chars produced from poultry manure by the method described herein exhibit enhanced activity for metal ion adsorption. |
FILED | Friday, April 11, 2008 |
APPL NO | 12/082593 |
ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Liquid purification or separation 210/688 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794714 | Kapczynski |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Darrell R. Kapczynski (Bishop, Georgia) |
ABSTRACT | Anti-peptide monoclonal antibodies (MAb's) specific for Exotic Newcastle Disease (END) are used for rapid diagnostic identification between poultry infected with vaccine strains of NDV (LaSota/B1) and END virus (ENDV). Exotic Newcastle Disease is a contagious and fatal viral disease of birds and poultry. The present invention provides for diagnostic detection of ENDV in commercial poultry. |
FILED | Friday, March 14, 2008 |
APPL NO | 12/075920 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794734 | Ayalew et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
INVENTOR(S) | Sahlu Ayalew (Stillwater, Oklahoma); Anthony W. Confer (Stillwater, Oklahoma) |
ABSTRACT | Vaccine preparations for the prevention and treatment of bovine respiratory disease (BRD) and, in particular, its most severe form, termed “shipping fever”, are provided. The preparations comprise chimeric proteins comprising immunodominant epitopes of recombinant Mannheimia haemolytica outer membrane protein PlpE, and immunodominant epitopes of recombinant M. haemolytica leukotoxin. |
FILED | Friday, October 06, 2006 |
APPL NO | 11/545069 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/255.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794939 | Maki et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
INVENTOR(S) | Wusi Chen Maki (Coeur d'Alene, Idaho); Brian John Filanoski (Spokane, Washington); Nirankar Mishra (Post Falls, Idaho); Shiva Rastogi (Post Falls, Idaho) |
ABSTRACT | The present invention provides for methods of DNA methylation detection. The present invention provides for methods of generating and detecting specific electronic signals that report the methylation status of targeted DNA molecules in biological samples. Two methods are described, direct and indirect detection of methylated DNA molecules in a nano transistor based device. In the direct detection, methylated target DNA molecules are captured on the sensing surface resulting in changes in the electrical properties of a nano transistor. These changes generate detectable electronic signals. In the indirect detection, antibody-DNA conjugates are used to identify methylated DNA molecules. RNA signal molecules are generated through an in vitro transcription process. These RNA molecules are captured on the sensing surface change the electrical properties of nano transistor thereby generating detectable electronic signals. |
FILED | Monday, February 26, 2007 |
APPL NO | 11/678933 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795497 | Daniell |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida); Auburn University (Auburn, Alabama) |
INVENTOR(S) | Henry Daniell (Winter Park, Florida) |
ABSTRACT | The present invention provides for a method to circumvent the problem of using antibiotic resistant selectable markers. In particular, target plants are transformed using a plastid vector which contains heterologous DNA sequences coding for a phytotoxin detoxifying enzyme or protein. The selection process involves converting a antibiotic-free phytotoxic agent by the expressed phytotoxin detoxifying enzyme or protein to yield a nontoxic compound. The invention provides for various methods to use antibiotic-free selection in chloroplast transformation. |
FILED | Friday, December 19, 2003 |
APPL NO | 10/741379 |
ART UNIT | 1638 — Organic Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/278 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796241 | Lawrence et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Kurt C. Lawrence (Watkinsville, Maryland); Seung C. Yoon (Athens, Georgia); Gerald W. Heitschmidt (Athens, Georgia); Deana Jones (Athens, Georgia); Bosoon Park (Bogart, Georgia); Vernon A. Savage (Watkinsville, Georgia) |
ABSTRACT | An avian eggshell egg-check/crack detection system was developed to aide official egg graders. It includes an imaging system and a device to produce negative pressure in an egg chamber. |
FILED | Friday, September 05, 2008 |
APPL NO | 12/231785 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/53 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 07794230 | Lakin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
INVENTOR(S) | William D. Lakin (Johnson, Vermont); Scott A. Stevens (Erie, Pennsylvania) |
ABSTRACT | A system and method of modeling a circulatory system including a regulatory mechanism parameter. In one embodiment, a regulatory mechanism parameter in a lumped parameter model is represented as a logistic function. In another embodiment, the circulatory system model includes a compliant vessel, the model having a parameter representing a change in pressure due to contraction of smooth muscles of a wall of the vessel. |
FILED | Thursday, March 23, 2006 |
APPL NO | 11/387397 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Education and demonstration 434/270 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794557 | Hui et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Inframat Corporation (Farmington, Connecticut) |
INVENTOR(S) | Shiqiang Hui (Vancouver, Canada); Yide Zhang (Storrs, Connecticut); Danny Xiao (Willington, Connecticut); Mingzhong Wu (Fort Collins, Colorado) |
ABSTRACT | A precursor tape casting method is one in which chemical precursors are converted into a final chemical phase from green tapes to products. Because chemical precursors are employed rather than the final powder materials, sintering is not required to form the material. Lower annealing temperatures instead of high temperature sintering allow the formation of grains of about 1 to about 100 nanometers in the final material. In addition, when the final material is a magnetic/insulator composite, improved magnetic properties may be obtained. |
FILED | Friday, June 10, 2005 |
APPL NO | 11/150592 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/89.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794939 | Maki et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
INVENTOR(S) | Wusi Chen Maki (Coeur d'Alene, Idaho); Brian John Filanoski (Spokane, Washington); Nirankar Mishra (Post Falls, Idaho); Shiva Rastogi (Post Falls, Idaho) |
ABSTRACT | The present invention provides for methods of DNA methylation detection. The present invention provides for methods of generating and detecting specific electronic signals that report the methylation status of targeted DNA molecules in biological samples. Two methods are described, direct and indirect detection of methylated DNA molecules in a nano transistor based device. In the direct detection, methylated target DNA molecules are captured on the sensing surface resulting in changes in the electrical properties of a nano transistor. These changes generate detectable electronic signals. In the indirect detection, antibody-DNA conjugates are used to identify methylated DNA molecules. RNA signal molecules are generated through an in vitro transcription process. These RNA molecules are captured on the sensing surface change the electrical properties of nano transistor thereby generating detectable electronic signals. |
FILED | Monday, February 26, 2007 |
APPL NO | 11/678933 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795388 | Paavola et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
INVENTOR(S) | Chad D. Paavola (Mountain View, California); Jonathan D. Trent (Watsonville, California); Suzanne L. Chan (Oakland, California); Yi-Fen Li (Sunnyvale, California); R. Andrew McMillan (San Francisco, California); Hiromi Kagawa (Sunnyvale, California) |
ABSTRACT | The present invention provides chaperonin polypeptides which are modified to include N-terminal and C-terminal ends that are relocated from the central pore region to various different positions in the polypeptide which are located on the exterior of the folded modified chaperonin polypeptide. In the modified chaperonin polypeptide, the naturally-occurring N-terminal and C-terminal ends are joined together directly or with an intervening linker peptide sequence. The relocated N-terminal or C-terminal ends can be covalently joined to, or bound with another molecule such as a nucleic acid molecule, a lipid, a carbohydrate, a second polypeptide, or a nanoparticle. The modified chaperonin polypeptides can assemble into double-ringed chaperonin structures. Further, the chaperonin structures can organize into higher order structures such as nanofilaments or nanoarrays which can be used to produce nanodevices and nanocoatings. |
FILED | Monday, August 01, 2005 |
APPL NO | 11/194991 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796026 | Jorgensen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the United States National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Charles C. Jorgensen (Palo Alto, California); Bradley J. Betts (Burlingame, California) |
ABSTRACT | Methods and systems for using one or more radio frequency identification devices (RFIDs), or other suitable signal transmitters and/or receivers, to provide a sensor information communication path, to provide location and/or spatial orientation information for an emergency service worker (ESW), to provide an ESW escape route, to indicate a direction from an ESW to an ES appliance, to provide updated information on a region or structure that presents an extreme environment (fire, hazardous fluid leak, underwater, nuclear, etc.) in which an ESW works, and to provide accumulated thermal load or thermal breakdown information on one or more locations in the region. |
FILED | Wednesday, April 20, 2005 |
APPL NO | 11/111620 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/539.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796726 | Gendreau et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
INVENTOR(S) | Keith Gendreau (Greenbelt, Maryland); Jose Vanderlei Martins (Greenbelt, Maryland); Zaven Arzoumanian (Greenbelt, Maryland) |
ABSTRACT | An X-ray diffraction and X-ray fluorescence instrument for analyzing samples having no sample preparation includes a X-ray source configured to output a collimated X-ray beam comprising a continuum spectrum of X-rays to a predetermined coordinate and a photon-counting X-ray imaging spectrometer disposed to receive X-rays output from an unprepared sample disposed at the predetermined coordinate upon exposure of the unprepared sample to the collimated X-ray beam. The X-ray source and the photon-counting X-ray imaging spectrometer are arranged in a reflection geometry relative to the predetermined coordinate. |
FILED | Wednesday, February 14, 2007 |
APPL NO | 11/706693 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/46 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07794837 | Lippa et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia) |
INVENTOR(S) | Katrice A. Lippa (Gaithersburg, Maryland); Catherine A. Rimmer (Gaithersburg, Maryland); Lane C. Sander (Gaithersburg, Maryland) |
ABSTRACT | A stationary phase for a liquid chromatograph and process for making is provided. The stationary phase material may have a modified base substrate and a fluorinated carboxylic acid covalently bonded thereto through an amide or ester bond. The stationary phase may have a substantially consistent shape selectivity characteristic with an αTBN/BaP of less than 1 within a temperature range of at least 10-70° C. Advantageously, a fluorinated stationary phase has a shape selectivity characteristic exhibited with an αTBN/BaP of less than 1 with a mobile phase having up to at least 30% water. A process for making the stationary involves mixing a substrate material or fluorinated carboxylic acid with a reactive alkylsilane linker and at least one organic solvent to form a first solution. The other of the substrate material or fluorinated carboxylic acid is then added to the first solution, or to a product separated from the first solution, to form a second solution. The second solution is reacted to form the stationary phase. |
FILED | Wednesday, August 06, 2008 |
APPL NO | 12/186728 |
ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Stock material or miscellaneous articles 428/405 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795373 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
INVENTOR(S) | Yuning Li (Mississauga, Canada); Beng S. Ong (Mississauga, Canada); Yiliang Wu (Mississauga, Canada) |
ABSTRACT | A polymer of Formula or structure (I) wherein at least one of R1 and R2 is a suitable hydrocarbon, hydrogen, a heteratom containing group, or a halogen; Ar and Ar′ represent an aromatic moiety; x, y, a, b, c, d, e, f, and g represent the number of groups or rings, respectively; and n represents the number of repeating units. |
FILED | Thursday, April 06, 2006 |
APPL NO | 11/399091 |
ART UNIT | 1796 — Organic Chemistry |
CURRENT CPC | Synthetic resins or natural rubbers 528/380 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795614 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
INVENTOR(S) | Yiliang Wu (Mississauga, Canada); Hadi K Mahabadi (Mississauga, Canada); Beng S Ong (Mississauga, Canada); Paul F Smith (Oakville, Canada) |
ABSTRACT | An electronic device including in any sequence: (a) a semiconductor layer; and (b) a phase-separated dielectric structure comprising a lower-k dielectric polymer and a higher-k dielectric polymer, wherein the lower-k dielectric polymer is in a higher concentration than the higher-k dielectric polymer in a region of the dielectric structure closest to the semiconductor layer. |
FILED | Monday, April 02, 2007 |
APPL NO | 11/695138 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/47 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796487 | Chu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Seagate Technology LLC (Scotts Valley, California) |
INVENTOR(S) | Patrick Breckow Chu (Wexford, Pennsylvania); Mark Ian Lutwyche (Mars, Pennsylvania); Tim Rausch (Gibsonia, Pennsylvania); William Albert Challener (Sewickley, Pennsylvania); Thomas Dean Milster (Tucson, Arizona) |
ABSTRACT | An apparatus includes a moveable arm for positioning an optical transducer adjacent to a storage medium, a light source, and an elliptical or ellipsoid shaped mirror mounted for reflecting light from the light source to the optical transducer. The elliptical mirror can be positioned on an ellipse, the moveable arm can pivot about an axis passing through a first focus of the ellipse, and the light source can direct light from a point on a second axis passing through a second focus of the ellipse to the elliptical minor. The light source can include a fixed laser and a moveable mirror mounted to pivot about the second axis or a moveable laser mounted to pivot about the second axis. A method performed by the apparatus is also provided. |
FILED | Tuesday, May 10, 2005 |
APPL NO | 11/125556 |
ART UNIT | 2627 — Selective Visual Display Systems |
CURRENT CPC | Dynamic information storage or retrieval 369/112.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07796791 | Tsougarakis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | ConforMIS, Inc. (Burlington, Massachusetts) |
INVENTOR(S) | Konstantinos Tsougarakis (Mountain View, California); Daniel Steines (Palo Alto, California); Bhaskar Rao Vissa (San Jose, California); Philipp Lang (Lexington, Massachusetts); Barry J. Linder (Danville, California) |
ABSTRACT | The present invention relates to methods for determining meniscal size and shape for use in designing therapies for the treatment of various joint diseases. The invention uses an image of a joint that is processed for analysis. Analysis can include, for example, generating a thickness map, a cartilage curve, or a point cloud. This information is used to determine the extent of the cartilage defect or damage and to design an appropriate therapy, including, for example, an implant. Adjustments to the designed therapy are made to account for the materials used. |
FILED | Friday, November 07, 2003 |
APPL NO | 10/704325 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 07793606 | Olivier et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | ION Geophysical Corporation (Houston, Texas) |
INVENTOR(S) | André W. Olivier (River Ridge, Louisiana); Lloyd Joseph LaCour, Jr. (Sequim, Washington) |
ABSTRACT | A position controller capable of controlling the depth or lateral position of a towed array. The position controller comprises a tubular fuselage from which a pair of wings may be extended over a range of sweep angles between fully open and stowed positions. In fully or partly open positions, two wings present a positive angle of attack relative to the axis of the fuselage. In the stowed position, the wings are fully retracted into a wing receptacle within the fuselage for unfettered passage into and out of a submarine on the array deployment and retrieval handling system. |
FILED | Tuesday, February 13, 2007 |
APPL NO | 11/674539 |
ART UNIT | 3617 — Printing/Measuring and Testing |
CURRENT CPC | Ships 114/245 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794657 | Stewart |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cantimer, Inc. (Menlo Park, California) |
INVENTOR(S) | Ray F. Stewart (Redwood City, California) |
ABSTRACT | A device is disclosed which is a highly sensitive and selective sensor. The device is comprised of a sensor material secured into a fixed position on substrate, a deformable arm and a signaling component which creates a detectable signal in response to movement of the arm. The sensitivity of the device is enhanced by using a sensor material which undergoes a dramatic change in volume which may be accompanied by a phase change in response contact with a target such a molecule of interest. The selectivity of the device is enhanced by incorporating highly specific binding receptors (e.g. antibodies) into the sensor material which receptors bind to specific targets (e.g. peptide epitopes). The binding of the target molecule to the receptor causes the sensor material to change dramatically in volume thereby moving the arm causing the signaling component (e.g. a piezoresistor) to create a detectable signal (e.g. change in resistance) thereby indicating the present of the target. |
FILED | Friday, May 28, 2004 |
APPL NO | 10/857634 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794713 | Sabbadini et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lpath, Inc. (San Diego, California) |
INVENTOR(S) | Roger A. Sabbadini (Lakeside, California); Amy L. Cavalli (San Diego, California); William A. Garland (San Clemente, California) |
ABSTRACT | Monotherapies and combination therapies for treating hyperproliferative disorders are described, as are compositions for performing such methods. |
FILED | Friday, October 28, 2005 |
APPL NO | 11/261935 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07794797 | Vasenkov |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
INVENTOR(S) | Aleksey V. Vasenkov (Huntsville, Alabama) |
ABSTRACT | The present invention is a catalytic chemical vapor deposition method and apparatus for synthesizing carbon nanotubes and/or carbon nanofibers (CNTs) on a substrate by selectively heating a catalyst for CNT synthesis on or near the surface of the substrate. Selective heating of the catalyst is achieved using an exothermic oxidation reaction on the surface of the catalyst. Selective heating of the catalyst prevents heating of the substrate and enables the synthesis of CNTs on temperature sensitive substrates. |
FILED | Tuesday, January 30, 2007 |
APPL NO | 11/668741 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating processes 427/450 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07795009 | Heyduk |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
INVENTOR(S) | Tomasz Heyduk (Ballwin, Missouri) |
ABSTRACT | The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules. |
FILED | Thursday, August 09, 2007 |
APPL NO | 11/836333 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 07797280 | Garey |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Ronald Garey (Washington, District of Columbia) |
ABSTRACT | Methods and systems consistent with this invention manage a database of delivery destination information. Such methods and systems identify an item to be delivered to a destination; determine a batch of items for delivery having the item to be delivered to the destination; determine when the batch of items has been delivered: and update the database to indicate a delivery of the item destined to the destination after determining when the batch of items has been delivered. |
FILED | Tuesday, November 06, 2001 |
APPL NO | 10/415804 |
ART UNIT | 2163 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/643 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07797543 | Campbell et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Leo J. Campbell (Arlington, Virginia); Jon L. Cook (Alexandria, Virginia); Charles R. Chamberlain (Arlington, Virginia); Michael J. McGrath (Fairfax, Virginia); Isadore Schoen (Burke, Virginia) |
ABSTRACT | Systems and methods are disclosed for authenticating electronic messages. A data structure is generated by a computer server which allows for the authentication of the contents and computer server identity of a received electronic message and provides a trusted stamp to authenticate when the message was sent. Data which can authenticate the message, the computer server identity, and the time the message was sent is included into a data structure which is called an Electronic PostMark (EPM). |
FILED | Friday, September 29, 2000 |
APPL NO | 09/675677 |
ART UNIT | 2439 — Cryptography and Security |
CURRENT CPC | Electrical computers and digital processing systems: Support 713/178 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 07794001 | Blackwell et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Charlotte-Mecklenburg Hospital Authority d/b/a Carolinas Medical Center (Charlotte, North Carolina) |
INVENTOR(S) | Thomas H. Blackwell (Charlotte, North Carolina); Kevin T. Staley (Charlotte, North Carolina) |
ABSTRACT | A mobile medical facility capable of treating a plurality of patients and being transported over the roadways without requiring extensive transporting means. In general the mobile medical facility includes a trailer. The trailer defines a floor area and has at least a first and second configuration. In the first configuration, the floor area is reduced to allow for transporting of the trailer over the public highways. In the second configuration, the floor area of the trailer is expanded and large enough to support a plurality of beds for treating patients. In some embodiments, the floor area in the second configuration may be at least twice as large as the floor area in the first configuration. |
FILED | Monday, May 09, 2005 |
APPL NO | 10/552135 |
ART UNIT | 3612 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Land vehicles: Bodies and tops 296/24.380 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 07794557 | Hui et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Inframat Corporation (Farmington, Connecticut) |
INVENTOR(S) | Shiqiang Hui (Vancouver, Canada); Yide Zhang (Storrs, Connecticut); Danny Xiao (Willington, Connecticut); Mingzhong Wu (Fort Collins, Colorado) |
ABSTRACT | A precursor tape casting method is one in which chemical precursors are converted into a final chemical phase from green tapes to products. Because chemical precursors are employed rather than the final powder materials, sintering is not required to form the material. Lower annealing temperatures instead of high temperature sintering allow the formation of grains of about 1 to about 100 nanometers in the final material. In addition, when the final material is a magnetic/insulator composite, improved magnetic properties may be obtained. |
FILED | Friday, June 10, 2005 |
APPL NO | 11/150592 |
ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/89.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 07793559 | Susfalk et al. |
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FUNDED BY |
|
APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education, on Behalf of the Desert Research Institute (Reno, Nevada) |
INVENTOR(S) | Richard Susfalk (Reno, Nevada); James Brock (Boise, Idaho) |
ABSTRACT | Certain disclosed embodiments provide sensing devices of the type useable to obtain measurements from a plurality of positions of a substrate, such as in a well, body of water, soil, snow pack, or ice pack. In a particular implementation, the sensing device includes a housing having a length. A plurality of digital sensors are disposed at a plurality of positions along the length of the housing. A communication bus is in communication with each of the plurality of sensors. A data collection or transmission device is in communication with the communication bus. Further implementations provide sensing devices having a housing formed from a plurality of modular sections. Sensors are disposed in at least one of the modular sections. Also disclosed are networks formed from a plurality of the disclosed devices. |
FILED | Friday, February 02, 2007 |
APPL NO | 11/670903 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/866.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 07797152 | Waite et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia) |
INVENTOR(S) | David P. Waite (Silver Spring, Maryland); Richard O. Wyckoff (Woodstock, Maryland) |
ABSTRACT | The present invention is a method of database searching. First, a language is selected and elements received. The system is searched to identify a unit number associated with each element, which is linked to a data unit containing morphological variants of the element. If none are identified, the element is broken into sub-textual units that may contain a prefix, compound-prefix, and/or suffix along with a primary element. A unit number is then obtained for the primary element. If this does not result in a match, the elements may be saved in a database for further linguistic development. A unit number associated with each matched element is then chosen, and the elements contained in the data units linked to the unit numbers are compared to a database index. If an element is associated with multiple unit numbers, this process is repeated until all data units have been compared to the database. |
FILED | Friday, February 17, 2006 |
APPL NO | 11/363299 |
ART UNIT | 2626 — Selective Visual Display Systems |
CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/9 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07796251 | Ponsardin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | ITT Manufacturing Enterprises, Inc. (Wilmington, Delaware) |
INVENTOR(S) | Patrick Louis Ponsardin (Placitas, New Mexico); Christopher Scott Kletecka (Willoughby Hills, Ohio); Jeromy Paul Rezac (Albuquerque, New Mexico) |
ABSTRACT | Systems and methods for fast and sensitive standoff surface-hazard detection with high data throughput, high spatial resolution and high degree of pointing flexibility. The system comprises a first hand-held unit that directs an excitation beam onto a surface that is located a distance away from the first unit and an optical subsystem that captures scattered radiation from the surface as a result of the beam of light. The first unit is connected via a link that includes a bundle of optical fibers, to a second unit, called the processing unit. The processing unit comprises a fiber-coupled spectrograph to convert scattered radiation to spectral data, and a processor that analyzes the collected spectral data to detect and/or identify a hazardous substance. The second unit may be contained within a body-wearable housing or apparatus so that the first unit and second unit together form a man-portable detection assembly. In one embodiment, the system can continuously and without interruptions scan a surface from a 1-meter standoff while generating Raman spectral-frames at rates of 25 Hz. |
FILED | Tuesday, March 20, 2007 |
APPL NO | 11/688434 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/301 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 14, 2010.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100914.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page