FedInvent™ Patents
Patent Details for Tuesday, September 28, 2010
This page was updated on Monday, March 27, 2023 at 01:54 AM GMT
Department of Health and Human Services (HHS)
| US 07803351 | Sharma et al. |
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| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Vijay Sharma (Wildwood, Missouri); David Piwnica-Worms (Ladue, Missouri) |
| ABSTRACT | Novel blood-brain barrier permeant amyloid-targeting peptides and peptide conjugates are described. The peptide conjugates include a radioisotope or other label in a stable complex that translocates across brain capillary endothelial cell monolayers. The labeled peptide conjugate binds to amyloid plaques (Aβ) associated with Alzheimer's disease, and is useful for the targeted delivery of therapeutic and diagnostic molecules into the brain. |
| FILED | Friday, August 19, 2005 |
| APPL NO | 11/207954 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.690 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803363 | Klose et al. |
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| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Karl E. Klose (San Antonio, Texas); Bernard P. Arulanandam (San Antonio, Texas) |
| ABSTRACT | In one embodiment, there is disclosed a method of inducing an immune response in a subject comprising administering to the subject a Francisella bacterium that includes an alteration in the nucleic acid sequence encoding the mglA, iglA, iglB, iglC, or iglD gene of the bacterium. |
| FILED | Wednesday, February 28, 2007 |
| APPL NO | 11/680375 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803364 | Trapp et al. |
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| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Bruce Trapp (Bentleyville, Ohio); Robert Miller (Cleveland Heights, Ohio) |
| ABSTRACT | An isolated multipotent neural stem cells has a phenotype identified by expression of the protein β-tubulin IV and Olig2 and the absence of the proteins NG2, PLP, and GFAP. |
| FILED | Friday, November 17, 2006 |
| APPL NO | 11/601565 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803380 | Takafuji et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Vivian Takafuji (Alexandria, Virginia); Xin Wei Wang (Rockville, Maryland) |
| ABSTRACT | Based on the observation of the cooperation of osteopontin (OPN) and matrixmetalloproteinase-9 (MMP-9) in the promotion of the metastatic phenotype, therapies and diagnostic assays are disclosed for the treatment of a tumor that overexpresses OPN, such as hepatocellular carcinoma (HCC), for example metastatic HCC. In one example, methods of treating a tumor include administration of an agent that reduces cellular invasion resulting from the interaction between a fragment of OPN (OPN-5kD) generated by MMP-9 cleavage and CD44 receptor. Examples of such agents include fragments of OPN-5kD and antibodies specific for OPN-5kD. Therapeutic compositions are also provided that include such agents. Also provided are methods of diagnosing or prognosing a tumor, for example by detecting expression of OPN-5kD peptide or OPN-c mRNA in a biological sample obtained from the subject. Also provided are antibodies that specifically bind OPN-5kD. |
| FILED | Friday, December 19, 2008 |
| APPL NO | 12/340211 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803386 | Schneerson et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Rachel Schneerson (Bethesda, Maryland); Stephen Leppla (Bethesda, Maryland); John B. Robbins (Chevy Chase, Maryland); Joseph Shiloach (Rockville, Maryland); Joanna Kubler-Kielb (Rockville, Maryland); Darrell Liu (Bethesda, Maryland); Fathy Majadly (Frederick, Maryland) |
| ABSTRACT | Immunogenic compositions and methods for eliciting an immune response against B. anthracis and other bacilli are provided that include immunogenic conjugates of a poly-γ-glutamic acid (γPGA) polypeptide of B. anthracis, or of another Bacillus that expresses a γPGA polypeptide. The γPGA conjugates elicit an effective immune response against B. anthracis, or against another Bacillus, in mammalian hosts to which the conjugates are administered. |
| FILED | Friday, June 04, 2004 |
| APPL NO | 10/559825 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/234.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803389 | Bzik et al. |
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| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | David J. Bzik (Grantham, New Hampshire); Barbara A. Fox (Grantham, New Hampshire) |
| ABSTRACT | The present invention relates to a mutant Toxoplasma gondii which exhibits enhanced homologous recombination. The mutant of the present invention is a knockout in the KU80-dependent nonhomologous end-joining pathway which finds application in generating T. gondii gene knockouts and gene replacements for use in vaccine and drug development. |
| FILED | Friday, February 27, 2009 |
| APPL NO | 12/394365 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/273.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803399 | Cheresh et al. |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); Board of Trustees of the Leland Stanford, Jr., University (Palo Alto, California) |
| INVENTOR(S) | David A. Cheresh (Encinitas, California); John Hood (San Diego, California); Mark Bednarski (Los Altos, California) |
| ABSTRACT | αvβ3 Integrin receptor targeting liposomes comprise a cationic amphiphile such as a cationic lipid, a neutral lipid, and a targeting lipid. The targeting lipid includes a non-peptidic αvβ3 integrin antagonist. |
| FILED | Monday, April 03, 2006 |
| APPL NO | 11/396743 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803530 | Cohenford et al. |
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| ASSIGNEE(S) | Cytyc Corporation (Marlborough, Massachusetts) |
| INVENTOR(S) | Menashi A. Cohenford (West Warwick, Rhode Island); Brian Lentrichia (Acton, Massachusetts) |
| ABSTRACT | The invention provides methods for detection and typing of HPV infection using PNA probes. More specifically, methods are provided for detecting high-risk types of HPV infection with minimal numbers of PNA probes or using PNA probes to selectively amplify only high-risk types of HPV. |
| FILED | Wednesday, December 18, 2002 |
| APPL NO | 10/323188 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803542 | Xiao et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yi Xiao (Goleta, California); Arica Lubin (Santa Barbara, California); Kevin Plaxco (Santa Barbara, California) |
| ABSTRACT | The invention provides a general “signal-on” architecture for oligonucleotide-based detectors that leads to order of magnitude increases in signal gain and sensitivity as compared to prior art detectors. The detectors of the invention rely on base pairing between two oligonucleotide strands, the sensor strand and the blocker strand. In the ‘off’ position of the detector, i.e., in the absence of target, the blocker strand and sensor strand are base-paired. As shown in FIG. 1, the formation of comparatively rigid, duplex DNA prevents the redox moiety from approaching the electrode surface, thereby suppressing Faradaic currents. When target is added to the system, the target displaces the blocker strand, binds to the sensor strand, liberating the end of the redox-labeled oligonucleotide to produce a flexible element. This, in turn, allows the redox moiety to collide with the electrode surface, producing a readily detectable Faradaic current. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 11/564674 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803546 | Agus |
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| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | David B. Agus (Beverly Hills, California) |
| ABSTRACT | Described herein are methods for treating cancer and other disease conditions in individuals who have either developed a resistance to conventional tyrosine kinase inhibitor (TKI) therapy or who are non-responsive ab initio to conventional TKI therapy. In various embodiments, the methods include administering to a patient a resistance-surmounting quantity of a TKI on a weekly or semi-weekly basis. Alternate embodiments of the present invention include a diagnostic method for assessing an individual's probability of being resistant to TKI therapy, based upon an expression level of epithelial membrane protein-1 (EMP-1); one of the genes believed to be responsible for TKI resistance. The methods of the present invention may be particularly useful in the treatment of lung, breast, prostate, ovarian, brain and colon cancers. The methods of the present invention may be effective in blocking the HER-2 kinase domain either in addition to or in lieu of blocking the EGFR kinase domain. |
| FILED | Friday, February 23, 2007 |
| APPL NO | 11/678420 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803557 | Serhan et al. |
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| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Charles N. Serhan (Needham, Massachusetts); Makoto Arita (Brookline, Massachusetts) |
| ABSTRACT | The present invention is directed to methods for the identification and uses of a receptors that interact with anti-inflammatory compounds derived from eicosapentaenoic acid (EPA). The receptors are of the G-protein coupled receptor (GPCR) family, and are useful to screen candidate substances for anti-inflammatory activity, especially substances that are analogs of EPA. Such analogs are termed “resolvins”; and are typically di- and tri-hydroxy EPA analogs. One analog herein denoted Resolvin E1 was identified in humans and prepared by total synthesis. In nanomolar range Resolvin E1 reduces dermal inflammation, peritonitis, dendritic cells (DCs) migration and IL-12 production. Also described herein is a receptor denoted Reso ER1 that interacts with Resolvin E1 to attenuate cytokine induced activation of inflammatory pathways mediated by transcription factor (NF)-kB. Treatment of DCs with small-interfering RNA specific for ResoE1 eliminated the ligand's ability to regulate IL-12. Assays of anti-inflammatory activity based on these discoveries are also described. |
| FILED | Monday, March 10, 2008 |
| APPL NO | 12/045427 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803559 | Diamond et al. |
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| ASSIGNEE(S) | The Regents of the University of CA (Oakland, California) |
| INVENTOR(S) | Marc I Diamond (San Francisco, California); Sonia K Pollitt (San Mateo, California) |
| ABSTRACT | Disclosed herein is a high-throughput assay to measure intracellular polyglutamine protein aggregation using fluorescence resonance energy transfer (FRET). Three libraries of over 3000 biologically active small molecules were screened for inhibitory activity, and a lead compound was characterized in detail. Y-27632, an inhibitor of the Rho-associated kinase p160ROCK, diminished polyglutamine protein aggregation at micromolar concentrations, and reduced neurodegeneration in a Drosophila model of polyglutamine disease. |
| FILED | Monday, August 09, 2004 |
| APPL NO | 10/915203 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803560 | Charo et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Israel F. Charo (San Francisco, California); Shaun R. Coughlin (Tiburon, California) |
| ABSTRACT | Novel human chemokine receptors, MCP-1RA and MCP-1RB, and processes for producing them are disclosed. The receptors, which are alternately spliced versions of MCP-1 receptor protein may be used in an assay to identify antagonists of MCP-1 which are therapeutically useful in the treatment of atherosclerosis and other diseases characterized by monocytic infiltrates. |
| FILED | Monday, February 05, 2007 |
| APPL NO | 11/702711 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803561 | Filardo et al. |
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| ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island) |
| INVENTOR(S) | Edward J. Filardo (East Grenwich, Rhode Island); Edmond Sabo (Providence, Rhode Island) |
| ABSTRACT | The invention provides methods of identifying metastatic disease as well as ligands such as antibodies that bind to GPR30. These antibodies are useful in the detection or treatment of endocrine tumors. |
| FILED | Tuesday, February 06, 2007 |
| APPL NO | 11/703347 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803565 | Frucht et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | David M. Frucht (Vienna, Virginia); Hui Fang (Germantown, Maryland) |
| ABSTRACT | It is disclosed herein that isolated lymphocytes, such as human B-cells and CD4+ T-cell can be used to determine an amount of lymphocyte-associated anthrax lethal toxin activity present. Methods of using isolated lymphocytes to identify anthrax therapeutic agents and to determine the efficacy of a potential anthrax therapeutic are disclosed. Methods are also provided for diagnosing and treating anthrax infections. |
| FILED | Wednesday, April 05, 2006 |
| APPL NO | 11/399003 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803566 | Terajima et al. |
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| ASSIGNEE(S) | The University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Masanori Terajima (Holden, Massachusetts); John Cruz (Shrewsbury, Massachusetts); Francis A. Ennis (Shrewsbury, Massachusetts) |
| ABSTRACT | The present invention relates to the identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes. Two vaccinia virus CD8+ T cell epitopes restricted by the most common human MHC class I allele, HLA-A0201 have been identified. Both epitopes are highly conserved in vaccinia and variola viruses. The induction of the T cell responses following primary vaccination is demonstrated by the kinetics of epitope specific CD8+ T cells in 3 HLA-A0201 individuals. This information will be useful for the design and analyses of the immunogenicity of experimental vaccinia vaccines, and for basic studies of human T cell memory. |
| FILED | Friday, March 30, 2007 |
| APPL NO | 11/731784 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803568 | Wei et al. |
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| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alexander Wei (West Lafayette, Indiana); Yan Zhao (West Lafayette, Indiana) |
| ABSTRACT | The present invention is directed to methods and products related to carbodithioate ligands bonded to surfaces. The invention is further directed to molecular and biomolecular sensing methods based on analyte recognition by carbodithioate ligands bonded to surfaces. |
| FILED | Thursday, April 20, 2006 |
| APPL NO | 11/407751 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.920 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803594 | Read et al. |
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| ASSIGNEE(S) | University of Buffalo, Office of Science and Tech Transfer (Amherst, New York) |
| INVENTOR(S) | Laurie K. Read (Orchard Park, New York); John Fisk (Amherst, New York) |
| ABSTRACT | The invention relates to enzymes in Trypanosoma brucei, and in particular, protein arginine methyltransferases. A unique, highly active recombinant arginine methyltransferase capable of monomethylation of peptides and proteins is described. |
| FILED | Thursday, August 06, 2009 |
| APPL NO | 12/536870 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803595 | Spiegel et al. |
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| ASSIGNEE(S) | Sankyo Company, Limited (Tokyo, Japan); Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Sarah Spiegel (McLean, Virginia); Takafumi Kohama (Tokyo, Japan) |
| ABSTRACT | Nucleic acids encoding mouse and human sphingosine kinase type 2 isoforms, methods for detecting agents or drugs which inhibit or promote sphingosine activity and therapeutic agents containing peptides or antibodies to peptides encoded by such nucleic acids. |
| FILED | Tuesday, August 14, 2007 |
| APPL NO | 11/891964 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803596 | Yurieva et al. |
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| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Olga Yurieva (New York, New York); John Kuriyan (Riverdale, New York); Michael E. O'Donnell (Hastings-on-Hudson, New York); David Jeruzalmi (New York, New York) |
| ABSTRACT | A DNA Polymerase has been identified in a thermophile that functions as a chromosomal replicase. The specific enzyme is a holoenzyme III that has been identified in Thermus thermophilus, and corresponds to Polymerase III in E. coli. The genes and the polypeptides corresponding to T.th. γ, τ, ε, α and β subunits that they encode are disclosed, as are probes, vectors, methods of preparation and the methods of use. The enzymes of the present invention and their components are particularly well suited for use in procedures for the preparation of DNA, such as PCR, because of the speed and accuracy that they are able to achieve. |
| FILED | Thursday, June 04, 2009 |
| APPL NO | 12/478741 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803602 | Comstock et al. |
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| ASSIGNEE(S) | The Brigham and Woman's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Laurie E. Comstock (Medfield, Massachusetts); Katja G. Weinacht (Denzlingen, Germany); Michael J. Coyne (North Attleboro, Massachusetts); Dennis L. Kasper (Charlestown, Massachusetts); Arthur O. Tzianabos (Reading, Massachusetts) |
| ABSTRACT | The present invention is directed to methods for producing and selecting new mutant strains of B. fragilis that constitutively express a particular capsular polysaccharide or only selected capsular polysaccharides; compositions directed to the new mutant strains of B. fragilis that constitutively express a particular capsular polysaccharide or only selected capsular polysaccharides; improved methods for purification of individual capsular polysaccharides; and compositions directed to new res02 and inv19 genes and their gene products. Significantly, the present invention provides methods and compositions for overexpressing and purifying immunomodulatory capsular polysaccharide A (PSA) in high yield. |
| FILED | Monday, August 20, 2007 |
| APPL NO | 11/894552 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803607 | Branton et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel Branton (Lexington, Massachusetts); Jene A Golovchenko (Lexington, Massachusetts) |
| ABSTRACT | There is provided a first reservoir containing a liquid solution including a molecule to be characterized and a second reservoir for containing a liquid solution including a molecule that has been characterized. A solid state support structure is provided including an aperture having a molecular entrance providing a fluidic connection to the first reservoir and a molecular exit providing a fluidic connection to the second reservoir. One carbon nanotube is provided having a longitudinal sidewall disposed as a molecular contacting surface at the aperture. A voltage source is connected in series with the carbon nanotube for electrically biasing the carbon nanotube, and an electrical current monitor is connected in series with the carbon nanotube for monitoring changes in electrical current through the nanotube corresponding to translocation of a molecule through the aperture. |
| FILED | Wednesday, June 11, 2008 |
| APPL NO | 12/157570 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803614 | Kawakami et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Yutaka Kawakami (Kanagawa, Japan); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess or prognoses a mammal afflicted with melanoma or metastata melanoma. This invention also provides immunogenic peptides derived from the MRT-1 melanoma antigen and a second melanoma antigen designated gp100. This invention further provides immunogenic peptides derived from the MART-1 melanoma antigen or gp100 antigen which have been modified to enhance their immunogenicity. The proteins and peptides provided can serve as an immunogen or vaccine to prevent or treat melanoma. |
| FILED | Wednesday, October 31, 2007 |
| APPL NO | 11/932255 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803622 | Engelhardt et al. |
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| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | John F. Engelhardt (Iowa City, Iowa); Dongsheng Duan (Iowa City, Iowa) |
| ABSTRACT | The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors. |
| FILED | Tuesday, February 15, 2005 |
| APPL NO | 11/058751 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803751 | Kozlov et al. |
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| ASSIGNEE(S) | Illumina, Inc. (San Diego, California) |
| INVENTOR(S) | Igor Kozlov (San Diego, California); Peter Melnyk (San Diego, California); Chanfeng Zhao (San Diego, California) |
| ABSTRACT | The invention provides a method of modifying a phosphomonoester moiety of a target compound. The method can include the steps of (a) providing a target compound having an electrophilic moiety and a phosphomonoester moiety; (b) contacting the target compound with a first carbodiimide compound under conditions for preferential addition of the first carbodiimide compound to the electrophilic moiety over the phosphomonoester moiety, thereby forming an electrophile-protected target compound; and (c) contacting the electrophile-protected target compound with a second carbodiimide compound and a nucleophilic compound under conditions for addition of the nucleophilic compound to the phosphomonoester. |
| FILED | Friday, December 09, 2005 |
| APPL NO | 11/298907 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803752 | Goldman et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Steven A. Goldman (Webster, New York); Abdellatif Benraiss (Astoria, New York) |
| ABSTRACT | The present invention relates to methods of inducing neuronal production in the brain, recruiting neurons to the brain, and treating a neurodegenerative condition by providing a nucleic acid construct encoding a neurotrophic factor, and injecting the nucleic acid construct intraventricularly into a subject's brain. |
| FILED | Wednesday, March 29, 2006 |
| APPL NO | 11/392020 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803758 | Khoshnan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ali Khoshnan (South Pasadena, California); Paul H. Patterson (Altadena, California) |
| ABSTRACT | The present invention provides methods and compositions for protecting cells from the toxicity of mutant huntingtin (Htt) protein and for treatment of Huntington's disease (HD). The methods generally involve administering to cells or a patient an effective amount of an IKK inhibitor. In addition, methods are provided for identifying therapeutics for the treatment of HD. |
| FILED | Tuesday, October 09, 2007 |
| APPL NO | 11/869501 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803772 | Levin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Eugene G. Levin (San Diego, California) |
| ABSTRACT | The invention relates to fragments of an amino acid sequence of mature, full length 24 kDa fibroblast growth factor-2 or an analog thereof. The fragments have an activity that inhibits the migration of cultured cells as well as inhibiting angiogenesis, tumor growth, or any other processes that involve the migration of cells in vivo. This fragment does not stimulate the proliferation of cells which is in contrast to activity shown by the mature, full-length 24 kDa fibroblast growth factor-2. The present invention also relates to a DNA molecule encoding the fragment, an expression vector and a transformed host containing the DNA molecule, and a method of producing the protein by culturing the transformed host. Moreover, the present invention relates to a therapeutic composition the 24 kDa fibroblast growth factor fragment and a pharmaceutically acceptable carrier. |
| FILED | Friday, October 23, 2009 |
| APPL NO | 12/604577 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803775 | Mochly-Rosen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Daria Mochly-Rosen (Menlo Park, California); Joan J. Kendig (Campbell, California); Sarah M. Sweitzer (Vallejo, California) |
| ABSTRACT | A method for managing withdrawal from an addictive substance is described. The method involves administering one or more peptides having specific activity for the ε and/or γ isozyme of protein kinase C (PKC). The peptide(s) can be administered prior to, concurrent with, or subsequent to administration of the addictive substance. Also described is a kit having at least one container containing a peptide having isozyme-specific activity for εPKC or γPKC and instructions for use. |
| FILED | Tuesday, May 22, 2007 |
| APPL NO | 11/805436 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803783 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Mark Lee (Los Altos Hills, California); Calvin Jay Kuo (Stanford, California); Tannishtha Reya (Chapel Hill, North Carolina); Irving L. Weissman (Stanford, California) |
| ABSTRACT | Methods and compositions are provided for the protection of normal cells from cytoreductive therapy that target proliferating cells, by administering an inhibitor of Wnt signaling pathways. Wnt signaling is critically important for homeostasis of the epithelial lining of the adult intestine and other proliferating normal adult tissues. |
| FILED | Friday, February 16, 2007 |
| APPL NO | 11/707386 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803784 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Qi-Jing Li (Mountain View, California); Chang-Zheng Chen (Stanford, California); Mark M. Davis (Atherton, California); Jacqueline Chau (Santa Clara, California) |
| ABSTRACT | MicroRNAs (miRNAs) are a diverse and abundant class of ˜22-nucleotide (nt) endogenous regulatory RNAs that play a variety of roles in animal cells by controlling gene expression at the posttranscriptional level. Increased miR-181a expression in mature T cells is shown to cause a marked increase in T cell activation and augments T cell sensitivity to peptide antigens. Moreover, T cell blasts with higher miR-181a expression become reactive to antagonists. The effects of miR-181a on antigen discrimination are in part achieved by dampening the expression of multiple negative regulators in the T cell receptor (TCR) signaling pathway, including PTPN22 and the dual specificity phosphatases DUSP5 and DUSP6. This results in a reduction in the TCR signaling threshold, thus quantitatively and qualitatively enhancing T cell sensitivity to antigens. |
| FILED | Wednesday, October 24, 2007 |
| APPL NO | 11/977506 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803905 | Farach-Carson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Mary C. Farach-Carson (Hockessin, Delaware); Daniel D. Carson (Hockessin, Delaware); Jeffrey B. Safran (Newark, Delaware) |
| ABSTRACT | The invention is directed to a polypeptide derived from domain IV of the extracellular matrix protein perlecan that can selectively adhere cells, nucleic acids encoding the inventive polypeptide, vectors comprising the nucleic acids, devices comprising a scaffold coated with the inventive polypeptide, and methods of adhering cells to a scaffold using the inventive polypeptide. |
| FILED | Monday, August 27, 2001 |
| APPL NO | 10/363376 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803908 | Depre et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Christophe Depre (New York, New York); Stephen F. Vatner (New York, New York) |
| ABSTRACT | The present invention provides novel nucleic acid and protein sequences for methods and compositions for treating, screening, and diagnosing cardiovascular disease and methods for using these genes and gene products for prevention of cardiac cell death and prevention of cardiac tissue damage resulting from ischemic events in cardiac tissue, as well as other tissue that is subject to damage resulting from an ischemic event. The genes, gene products and agents of the invention are also useful for treating other related clinical or coronary events such as angina, myocardial infarct (MI), and stroke, for monitoring the effectiveness of their treatment, and for drug development. The genes, gene products and agents of the present invention are also provided as pharmaceutical compositions for treatment of cardiovascular disease, ischemic heart disease, myocardial infarct and related conditions. Kits are also provided for the diagnosis, treatment and prognosis of cardiac diseases and related conditions. |
| FILED | Wednesday, March 01, 2006 |
| APPL NO | 11/365484 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803909 | Yeatman et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Timothy J. Yeatman (Tampa, Florida); Rosalyn B. Irby (Tampa, Florida) |
| ABSTRACT | The present invention provides a mutant oligonucleotide composition encoding a cellular c-Src tyrosine kinase oncogene. Methods for isolating, expressing and characterizing recombinant Src mutant polypeptide are also provided. The invention further relates to methods for utilizing such oligonucleotides, polypeptides, agonists and antagonists for applications, which relate to research, diagnostics, and clinical arts. More specifically, this invention provides methods of diagnosing, treating, immunizing, and creating transgenic animals based on use of such mutant Src. |
| FILED | Thursday, June 07, 2007 |
| APPL NO | 11/811158 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803912 | Olson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | John S. Olson (Houston, Texas); George N. Phillips, Jr. (Madison, Wisconsin) |
| ABSTRACT | The disclosure relates to recombinant adult human apohemoglobin (apo-rHb) in which the stability has been increased by replacement of an amino acid with a counterpart from another organism, such as a deep sea diving mammal. This mutated apo-rHb may be more stable and/or give higher production yields than unmutated adult human apo-rHb. The mutated apo-rHb may be produced in microorganisms, such as E. coli or yeast cells, or animal erythroid cells. Some apo-rHb of the present disclosure may be used as part of a blood substitute. |
| FILED | Wednesday, March 14, 2007 |
| APPL NO | 11/724007 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/385 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803913 | Dimitrov et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Dimiter S Dimitrov (Rockville, Maryland); Mei-Yun Zhang (Frederick, Maryland) |
| ABSTRACT | The present invention provides a method of identifying novel broadly crossreactive neutralizing monoclonal antibodies using sequential antigen panning of phage display libraries, antibodies obtained in accordance with such a method, as well as fusion proteins and conjugates comprising same, and related isolated or purified nucleic acid molecules, vectors, host cells, compositions, and methods of use to inhibit an infection, reduce the severity of an infection, treat an infection, and inhibit cancer. |
| FILED | Tuesday, May 06, 2003 |
| APPL NO | 10/513725 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803921 | Adjei et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Araba A. Adjei (Rochester, Minnesota); Eric D. Wieben (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota); Bianca A. Thomae (Chicago, Illinois) |
| ABSTRACT | Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described. |
| FILED | Tuesday, September 25, 2007 |
| APPL NO | 11/861075 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803932 | Wen et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Ying Wen (San Diego, California); Gregg G. Gundersen (Tenafly, New Jersey) |
| ABSTRACT | This invention provides a recombinant nucleic acid which, when introduced in vivo into a mammalian cell endogenously expressing EB1, inhibits the expression of EB1 therein, thereby reducing the amount of stable microtubules in the cell. This invention further provides related compositions, nucleic acids, cells and methods. |
| FILED | Friday, July 14, 2006 |
| APPL NO | 11/487244 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803970 | Dalton et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | James T. Dalton (Upper Arlington, Ohio); Duane D. Miller (Germantown, Tennessee); Mitchell S. Steiner (Germantown, Tennessee); Karen A. Veverka (Cordova, Tennessee); Dong Jin Hwang (Memphis, Tennessee); Jiyun Chen (Columbus, Ohio) |
| ABSTRACT | This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the SARM compounds have been found to have an unexpected androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. Other SARM compounds have been found to have an unexpected antiandrogenic activity of a nonsteroidal ligand for the androgen receptor. The SARM compounds, either alone or as a composition, are useful for a) male contraception; b) treatment of a variety of hormone-related conditions, for example conditions associated with Androgen Decline in Aging Male (ADAM), such as fatigue, depression, decreased libido, sexual dysfunction, erectile dysfunction, hypogonadism, osteoporosis, hair loss, anemia, obesity, sarcopenia, osteopenia, osteoporosis, benign prostate hyperplasia, alterations in mood and cognition and prostate cancer; c) treatment of conditions associated with Androgen Decline in Female (ADIF), such as sexual dysfunction, decreased sexual libido, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, endometriosis, breast cancer, uterine cancer and ovarian cancer; d) treatment and/or prevention of acute and/or chronic muscular wasting conditions; e) preventing and/or treating dry eye conditions; f) oral androgen replacement therapy; and/or g) decreasing the incidence of, halting or causing a regression of prostate cancer. |
| FILED | Monday, June 07, 2004 |
| APPL NO | 10/861905 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803982 | Margolskee et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Mount Sinai School of Medicine of New York University (New York, New York) |
| INVENTOR(S) | Robert Margolskee (Upper Montclair, New Jersey); Minqing Rong (Foster City, California); Sami Damak (Epalinges, Switzerland) |
| ABSTRACT | The present invention relates to the discovery, identification and characterization of a receptor protein, referred to herein as T1R3, which is expressed in taste receptor cells and associated with the perception of bitter and sweet taste. The invention encompasses transgenic animals and cells that do not express functional T1R3 protein, particularly knock-out animals and cells, and transgenic animals and cells that express a non-native T1R3 protein. Experimental model systems based on these animals and cells can be used to study T1R3-mediated taste transduction and responses of the components of the T1R3 signal transduction pathway to various tastants, furthering our understanding of the molecular biology and biochemistry of taste. Such model systems would also be useful for screening for novel tastants and taste modulators, such as enhancers of desirable flavors, and blockers of undesirable flavors. |
| FILED | Thursday, July 15, 2004 |
| APPL NO | 10/892632 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804595 | Matula et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Thomas Matula (Kirkland, Washington); Jingfeng Guan (Seattle, Washington) |
| ABSTRACT | A system and method for determining bubble shell properties using optical scattering. One or more ultrasound contrast agent (UCA) bubbles is placed in an imaging volume and illuminated with a laser. The UCA is exposed to pressure variations (e.g., using pulses of imaging or therapeutic ultrasound), while optical scattering data are collected and processed. The scattering intensity is related to the radius of the UCA. Thus, changes in the radius due to varying pressure conditions results in variations in the scattering intensity. The collected data are processed to provide a radius versus time (RT) relationship. The RT relationship is fit to one or more conventional dynamic models. The fitted empirical data can be used to determine one or more UCA parameters, such as shear modulus and shell viscosity. |
| FILED | Thursday, September 14, 2006 |
| APPL NO | 11/531998 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/338 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805183 | Keely et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Patricia Jo Keely (Madison, Wisconsin); Paolo P. Provenzano (Madison, Wisconsin); John Graham White (Madison, Wisconsin); Kevin William Eliceiri (Madison, Wisconsin) |
| ABSTRACT | The present invention provides methods and systems for evaluating biological materials for the diagnosis of disease, such as gland abnormalities, and the cancerous and precancerous conditions. Nonlinear optical microscopy techniques, such as MP microscopy and harmonic generation microscopy, are used to generate high resolution, three dimensional images of a test tissue, such as a biopsy tissue sample and tissue in whole organisms, that are analyzed, optionally in combination, to detect, identify and characterize tumor-associated collagen signatures. The presence, abundance and extent of histological features and structural motifs comprising tumor-associated collagen signatures may be directly and accurately correlated with the onset and progression of cancer, such as breast cancer. The present methods are capable of providing an accurate and selective diagnosis of cancer, and provide diagnostic information complementary to conventional diagnostic methods. |
| FILED | Thursday, June 21, 2007 |
| APPL NO | 11/766321 |
| ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805195 | Zealear |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | David L. Zealear (Nashville, Tennessee) |
| ABSTRACT | A laryngeal stimulation system including a sensor for detecting an occurrence of a respiratory signal in a subject and a laryngeal stimulator adapted for coupling to a laryngeal muscle and operable to stimulate the laryngeal muscle in response to the sensor detecting the occurrence of the respiratory signal is provided. A method for laryngeal stimulation including detecting an occurrence of a respiratory signal in a subject and then stimulating a laryngeal muscle in response to detecting the occurrence of the respiratory signal is also provided. |
| FILED | Friday, March 24, 2006 |
| APPL NO | 11/388789 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/42 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07802356 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | David T. Chang (Calabasas, California); Randall L. Kubena (Oak Park, California); Pamela R. Patterson (Los Angeles, California) |
| ABSTRACT | A method for manufacturing a resonator is presented in the present application. The method includes providing a handle substrate, providing a host substrate, providing a quartz substrate comprising a first surface opposite a second surface, applying interposer film to the first surface of the quartz substrate, bonding the quartz substrate to the handle substrate wherein the interposer film is disposed between the quartz substrate and the handle substrate, thinning the second surface of the quartz substrate, removing a portion of the bonded quartz substrate to expose a portion of the interposer film, bonding the quartz substrate to the host substrate, and removing the handle substrate and the interposer film, thereby releasing the quartz substrate. |
| FILED | Thursday, February 21, 2008 |
| APPL NO | 12/034852 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/594 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07802474 | Maguire et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jason M. Maguire (Middletown, Rhode Island); Gregory H. Ames (Wakefield, Rhode Island) |
| ABSTRACT | An accelerometer is provided for a fiber optic laser. Strain applied to the fiber optic laser results in an emission wavelength shift. The fiber optic laser is joined to a transducer and extends laterally across said transducer. Acceleration of the transducer in a predefined direction causes strain in said fiber optic laser. The transducer can have many possible designs. There is further provided a system for sensing acceleration which includes a pumping laser and a distributor joined to the fiber optic laser. Return signals from the fiber optic laser are provided to an interferometer and analysis circuitry. In the absence of a transducer, the system can operate as a strain sensor. |
| FILED | Monday, November 05, 2007 |
| APPL NO | 11/934850 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/514.160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07802558 | Panchal |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies Holding S.arl (Troy, Michigan) |
| INVENTOR(S) | Devan Panchal (Northants, United Kingdom) |
| ABSTRACT | A fuel delivery system for an internal combustion engine, the system comprising a common rail fuel reservoir having a primary rail axis and comprising a plurality of outlets at spaced locations along said rail axis and a plurality of fuel injectors arranged at spaced locations with respect to said rail axis. Each injector comprises an injector inlet, said plurality of fuel injectors defining first and second groups of injectors. The system further comprises first and second groups of pipes of substantially equal length, wherein each of said first group of pipes is of a first common design and connects the injector inlet of one of said first group of fuel injectors to an outlet displaced relative to said one of said first group of fuel injectors in a first direction substantially parallel to said rail axis, and each of said second group of pipes is of a second common design and connects the injector inlet of one of said second group of fuel injectors to an outlet displaced relative to said one of said second group of fuel injectors in a second direction substantially parallel to said rail axis and antiparallel to said first direction. Not more than one of said first group of injectors is disposed adjacent to said second group of injectors. |
| FILED | Monday, March 02, 2009 |
| APPL NO | 12/395905 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803116 | Sikdar et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington through its Center for Commericalization (Seattle, Washington) |
| INVENTOR(S) | Siddhartha Sikdar (Seattle, Washington); Yongmin Kim (Lake Forest Park, Washington); Kirk Beach (Seattle, Washington) |
| ABSTRACT | An ultrasound based technique for detecting and imaging vibrations in tissue caused by eddies produced during bleeding through punctured arteries or from organs. A clutter signal, normally suppressed in conventional color flow imaging, is employed to detect and characterize local tissue vibrations, to detect internal bleeding in an image, or as an audible or palpable signal, or a readout. Using a tissue vibration image, the origin and extent of vibrations relative to the underlying anatomy and blood flow can be visualized in real time, enabling measurements of vibration amplitude, frequency, and spatial distribution. Bleeding rate can be determined from the frequency and amplitude of the vibrations. Signal processing algorithms usable to identify tissue vibrations from an ensemble of 2D ultrasound data include those based on phase decomposition, spectral estimation using eigendecomposition, and spectral estimation using autoregressive modeling for isolating vibrations from clutter, blood flow, and noise. |
| FILED | Friday, October 01, 2004 |
| APPL NO | 10/574133 |
| ART UNIT | 3768 — Optics |
| CURRENT CPC | Surgery 6/462 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803218 | Armstrong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Bret D. Armstrong (Gilbert, Arizona); Steven M. Perry (Fountain Hills, Arizona); Anthony T. Matarazzo (Queen Creek, Arizona) |
| ABSTRACT | An on-board oxygen generating system is provided, which includes an air supply duct, a breathing gas duct, and an oxygen generator fluidly coupled between the air supply duct and the breathing gas duct. The oxygen generator is configured to enrich the oxygen content of air flowing from the air supply duct to the breathing gas duct. A drain valve assembly is fluidly coupled to the air supply duct and configured to move between: (i) an open position wherein condensation may drain from the air supply duct, and (ii) a closed position. |
| FILED | Monday, February 26, 2007 |
| APPL NO | 11/678803 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Gas separation: Apparatus 096/121 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803428 | Archer, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Harry L. Archer, Jr. (Alexandria, Virginia); Wayne J. Powell (Palm Harbor, Florida); Josephs T. Menke (Davenport, Indiana) |
| ABSTRACT | A method is provided for coating a steel surface of a workpiece. According to an aspect of the invention, a steel workpiece is subjected to a first embrittlement-relief baking operation to form a protective oxide layer on the steel surface. The protective oxide layer is de-scaled, and the steel surface is activated. A hydrogen bather coating is deposited on the activated steel surface, and activated. A zinc-nickel alloy is plated on the barrier coating, and subjected to a second embrittlement-relief baking operation. The porous plating is sealed with a conversion coat. The method is especially useful in making low to no hydrogen embrittlement cadmium-replacement steel parts. Also provided is a corrosion resistant coated steel workpiece. |
| FILED | Wednesday, May 28, 2008 |
| APPL NO | 12/214296 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803451 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Onyx Optics, Inc. (Dublin, California) |
| INVENTOR(S) | Huai-Chuan Lee (Albany, California); Helmuth E. Meissner (Pleasanton, California) |
| ABSTRACT | Manufacturing techniques and composite structures that are able to meet increasing demanding requirements for large-scale crystal composites (e.g., greater than 100-200 mm in dimensions) that can be manufactured within reasonable time frames. A method of making an optical composite comprises providing first and second components to be bonded along respective surfaces, treating at least one component over at least a portion of the respective surface, and thereafter, bringing the first and second components into optical contact for bonding along the surface having the treated layer. Treating can include one or more of processing the component to provide a porous interface layer, processing the component to form a pattern of channels on the surface to be bonded, and providing an optical coating on the surface to be bonded. |
| FILED | Thursday, July 27, 2006 |
| APPL NO | 11/460542 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/195.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803498 | Dressick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Walter J. Dressick (Waldorf, Maryland); Cynthia N. Kostelansky (Alexandria, Virginia); Terence L. Schull (Alexandria, Virginia) |
| ABSTRACT | A nanostructured electrode comprising a conductive electrode substrate having a surface functional group, a catalytic nanoparticle stabilized by a covalently-bound ligand bearing a peripheral functional group capable of interacting to the surface functional group, and a material capable of binding to the peripheral functional group. The conductive electrode substrate can be chemically modified and the surface functional group can create a layer of charge or chemical reactivity. The conductive electrode substrate can be chemically or electrochemically modified to create a surface functional group via covalent grafting capable of supporting multilayer deposition to create a layer of charge or chemical reactivity on the surface. The nanoparticle can be a platinum nanoparticle with covalently bonded negatively-charged ligands and the bridging material can be a polyelectrolyte. |
| FILED | Friday, August 25, 2006 |
| APPL NO | 11/513436 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/524 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803542 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yi Xiao (Goleta, California); Arica Lubin (Santa Barbara, California); Kevin Plaxco (Santa Barbara, California) |
| ABSTRACT | The invention provides a general “signal-on” architecture for oligonucleotide-based detectors that leads to order of magnitude increases in signal gain and sensitivity as compared to prior art detectors. The detectors of the invention rely on base pairing between two oligonucleotide strands, the sensor strand and the blocker strand. In the ‘off’ position of the detector, i.e., in the absence of target, the blocker strand and sensor strand are base-paired. As shown in FIG. 1, the formation of comparatively rigid, duplex DNA prevents the redox moiety from approaching the electrode surface, thereby suppressing Faradaic currents. When target is added to the system, the target displaces the blocker strand, binds to the sensor strand, liberating the end of the redox-labeled oligonucleotide to produce a flexible element. This, in turn, allows the redox moiety to collide with the electrode surface, producing a readily detectable Faradaic current. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 11/564674 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803552 | Rubin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mark A. Rubin (Cambridge, Massachusetts); Francesca DeMichelis (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to the identification and use of gene expression profiles with clinical relevance to prostate cancer. In particular, the invention provides the identity of genes whose expression, at the transcriptional and protein levels, is correlated with prostate cancer progression. Methods and kits are described for using these gene expression profiles in the study and/or diagnosis of prostate cancer diseases, in the prediction of prostate cancer progression, and in the selection and/or monitoring of treatment regimens. The invention also relates to the screening of drugs that target these genes or their protein products, in particular for the development of therapeutics for modulating prostate cancer progression. |
| FILED | Tuesday, October 27, 2009 |
| APPL NO | 12/607036 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803595 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sankyo Company, Limited (Tokyo, Japan); Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Sarah Spiegel (McLean, Virginia); Takafumi Kohama (Tokyo, Japan) |
| ABSTRACT | Nucleic acids encoding mouse and human sphingosine kinase type 2 isoforms, methods for detecting agents or drugs which inhibit or promote sphingosine activity and therapeutic agents containing peptides or antibodies to peptides encoded by such nucleic acids. |
| FILED | Tuesday, August 14, 2007 |
| APPL NO | 11/891964 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803712 | Kornilovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Pavel Kornilovich (Corvallis, Oregon); Yong Chen (Redwood City, California); Duncan Stewart (Menlo Park, California); R. Stanley Williams (Redwood, California); Philip J. Kuekes (Menlo Park, California); Mehmet Fatih Yanik (Stanford, California) |
| ABSTRACT | A mold with a protruding pattern is provided that is pressed into a thin polymer film via an imprinting process. Controlled connections between nanowires and microwires and other lithographically-made elements of electronic circuitry are provided. An imprint stamp is configured to form arrays of approximately parallel nanowires which have (1) micro dimensions in the X direction, (2) nano dimensions and nano spacing in the Y direction, and three or more distinct heights in the Z direction. The stamp thus formed can be used to connect specific individual nanowires to specific microscopic regions of microscopic wires or pads. The protruding pattern in the mold creates recesses in the thin polymer film, so the polymer layer acquires the reverse of the pattern on the mold. After the mold is removed, the film is processed such that the polymer pattern can be transferred on a metal/semiconductor pattern on the substrate. |
| FILED | Thursday, December 07, 2006 |
| APPL NO | 11/636264 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/691 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803764 | Polt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Robin L. Polt (Tuscon, Arizona); Edward Bilsky (Biddeford, Maine) |
| ABSTRACT | Amphipathic glycopeptides, the amino acid sequence of which comprises an N-terminal opioid message sequence, a C-terminal helical address sequence, and a linker sequence between the message sequence and the helical address sequence, where the C-terminal helical address sequence has a length of nine amino acids, and at least one of the amino acid residues of the peptide is glycosylated. The peptides are useful for relieving pain, providing analgesia and treating anxiety, depression, obesity, anorexia nervosa, phobias, schizophrenia, Parkinson's disease and Alzheimer's disease. |
| FILED | Friday, March 25, 2005 |
| APPL NO | 10/594515 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803921 | Adjei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Araba A. Adjei (Rochester, Minnesota); Eric D. Wieben (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota); Bianca A. Thomae (Chicago, Illinois) |
| ABSTRACT | Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described. |
| FILED | Tuesday, September 25, 2007 |
| APPL NO | 11/861075 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804157 | Sharma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Shashank Sharma (Sunnyvale, California); Theodore I. Kamins (Palo Alto, California) |
| ABSTRACT | A device configured to have a nanowire formed laterally between two electrodes includes a substrate and an insulator layer established on at least a portion of the substrate. An electrode of a first conductivity type and an electrode of a second conductivity type different than the first conductivity type are established at least on the insulator layer. The electrodes are electrically isolated from each other. The electrode of the first conductivity type has a vertical sidewall that faces a vertical sidewall of the electrode of the second conductivity type, whereby a gap is located between the two vertical sidewalls. Methods are also disclosed for forming the device. |
| FILED | Friday, June 16, 2006 |
| APPL NO | 11/454446 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/653 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804230 | Redding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies Holding S.arl (Troy, Michigan) |
| INVENTOR(S) | Keith Redding (Gillingham, United Kingdom); Martin Hardy (Gillingham, United Kingdom); Stavros Sfakianakis (Salonika, Greece) |
| ABSTRACT | A piezoelectric actuator for use in a fuel injector, the actuator comprising a stack of one or more piezoelectric elements for receipt within an accumulator chamber of the injector, distribution electrode means for generating an electric field within the stack and an electrical connector arrangement including a body member defining an external boundary and including a base portion and a stem portion projecting from the base portion. The base portion defines a base end face for abutment with an adjacent end face associated with the stack. Terminal means are provided for connection with an external power supply. The terminal means includes first and second terminal members disposed internal to the external boundary of the body member. The first and second terminal members are arranged side by side and disposed internal to the external boundary of the body member. The actuator further comprises first and second contact plates, each of which is connected electrically to a first end of a respective one of the first and second terminal members. The first and second terminal members are further connectable with an external power supply, in use, so as enable voltage supply to the distribution electrode means. The base portion of the body member defines a sealing surface for abutment with an internal surface defined by the accumulator chamber. |
| FILED | Tuesday, January 31, 2006 |
| APPL NO | 11/343339 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/348 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804441 | DeChiaro, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Louis F. DeChiaro, Jr. (Middletown, Delaware) |
| ABSTRACT | A process is provided to detect an object within a defined region using standing longitudinal cavity mode waves. The process includes disposing first and second electromagnetic reflectors within the region at opposite ends of the axis; transmitting an electromagnetic signal into the region in proximity to the first reflector, measuring a received signal in proximity to the second reflector, extracting an appropriate parameter from the received signal to obtain a received characteristic, comparing the received characteristic to an established characteristic that lacks the object to obtain a characteristic differential, and analyzing the characteristic differential to obtain a position of the object between the reflectors. The analyzing can be performed by Fourier transform across wave modes. In an alternate embodiment, the process involves first and second conductive lines disposed substantially parallel to the axis for a specified length and separated from each other by a specified width, the length and width bounding the defined region. The alternative process further includes transmitting an electromagnetic signal through the first line at a set frequency, returning the transmitted signal through the second line, measuring power from a reflected signal through the first line, adjusting the set frequency based on the measured power, extracting an appropriate parameter from the reflected signal to obtain a reflected characteristic, comparing the reflected characteristic to an established characteristic that lacks the object to obtain a characteristic differential, and analyzing the characteristic differential to obtain a position of the object along the length. |
| FILED | Friday, July 13, 2007 |
| APPL NO | 11/890098 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804454 | Mileski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul M. Mileski (Mystic, Connecticut) |
| ABSTRACT | A combined antenna transmitter joined for transmitting a message signal includes a switching signal source modulated by the message signal. The switching signal is provided to a transistor at an operating frequency. The transistor switches a high voltage input through the transistor, a choke inductor and a boost inductor. A bypass capacitor is provided between the inductors for shielding the high voltage input. An antenna is connected between the boost inductor and the transistor for transmitting a radio frequency signal at the operating frequency. There is thus provided a compact, efficient transmitter and antenna assembly for transmitting modulated message signals. |
| FILED | Wednesday, April 09, 2008 |
| APPL NO | 12/148075 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/722 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804741 | Snow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Trevor Snow (Bloomington, Indiana); Jeffrey M. Snow (Bloomington, Indiana) |
| ABSTRACT | The present disclosure relates to a method and system for finding and physically altering underground targets. Multiple nodes are dispersed into the ground and determine their spatial orientation using seismic waves, and then operate as an array to locate and properly time kinetic pulses to focus seismic waves on the target. |
| FILED | Wednesday, September 30, 2009 |
| APPL NO | 12/570960 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805005 | Simental et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Edmundo Simental (Alexandria, Virginia); Edward H. Bosch (Woodbridge, Virginia); Robert S. Rand (Fairfax Station, Virginia) |
| ABSTRACT | A wavelet-based band difference-sum ratio method reduces the computation cost of classification and feature extraction (identification) tasks. A Generalized Difference Feature Index (GDFI), computed using wavelets such as Daubechies wavelets, is employed in a method to automatically generate a large sequence of generalized band ratio images. In select embodiments of the present invention, judicious data mining of the large set of GDFI bands produces a small subset of GDFI bands suitable to identify specific Terrain Category/Classification (TERCAT) features. Other wavelets, such as Vaidyanathan, Coiflet, Beylkin, and Symmlet and the like may be employed in select embodiments. The classification and feature extraction (identification) performance of the band ratio method of the present invention is comparable to that obtained with the same or similar data sets using much more sophisticated methods such as discriminants, neural net classification, endmember Gibbs-based partitioning, and genetic algorithms. |
| FILED | Wednesday, July 12, 2006 |
| APPL NO | 11/484559 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/191 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805026 | Gill |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alcatel-Lucent USA Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Doglas M. Gill (South Orange, New Jersey) |
| ABSTRACT | In one embodiment, an optical modulator has a Mach-Zehnder interferometer (MZI) and an optical resonator coupled, via a tunable optical coupler, to one of the MZI internal arms. The optical resonator induces in the MZI frequency-dependent optical losses characterized by a comb of spectral resonances. The coupling strength between the optical resonator and the MZI set by the optical coupler controls the magnitude of the loss due to the resonances, while one or more optical phase shifter located in the optical resonator controls the spectral position of the resonances. Either the optical coupler or the optical phase shifter, or both, can be tuned to adjust the modulator's radio-frequency response curve. |
| FILED | Tuesday, July 08, 2008 |
| APPL NO | 12/168976 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805029 | Bayindir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mehmet Bayindir (Ankara, Turkey); Fabien Sorin (Cambridge, Massachusetts); Ayman F. Abouraddy (Boston, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Jeremy R. Arnold (Cambridge, Massachusetts); Yoel Fink (Brookline, Massachusetts); John D Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | There is provided a feedback-controlled self-heat-monitoring fiber, including an insulator having a fiber length with at least one metal-semiconductor-metal thermal sensing element along the fiber length and disposed at a position in a cross section of the fiber for sensing changes in fiber temperature. An electronic circuit is connected to the thermal sensing element for indicating changes in fiber temperature. A controller is connected for controlling optical transmission through an optical transmission element, that is disposed along the fiber length, in response to indications of changes in fiber temperature. |
| FILED | Thursday, March 05, 2009 |
| APPL NO | 12/380929 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805031 | Spillane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Sean M. Spillane (Mountain View, California); Raymond G. Beausoleil (Redmond, Washington); Charles Santori (Sunnyvale, California); Marco Fiorentino (Mountain View, California) |
| ABSTRACT | Various embodiments of the present invention are directed to color-center-based quantum computer architectures that are both scalable and defect tolerant and to methods for fabricating color-center-based quantum computer architectures. In one embodiment of the present invention, a node of a quantum computer architecture comprises a first photonic device configured to transmit electromagnetic waves, a color center embedded in diamond and coupled to the first photonic device, and a switch located between the first photonic device and a bus waveguide. The switch can be configured to selectively control transmission of electromagnetic waves between the bus waveguide and the color center. |
| FILED | Tuesday, June 02, 2009 |
| APPL NO | 12/476723 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805039 | Sanders et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Weatherford/Lamb, Inc. (Houston, Texas) |
| INVENTOR(S) | Paul E. Sanders (Madison, Connecticut); Edward M. Dowd (Madison, Connecticut); Brian J. Pike (Wallingford, Connecticut) |
| ABSTRACT | Methods and apparatus relate to optical fibers suitable for use in sensing applications exposed to radiation environments. The fibers include a core of pure silica or chlorine doped silica surrounded by a fluorinated silica cladding. These glasses for the core and cladding utilize dopants that resist radiation-induced attenuation. A two step process for forming the cladding can achieve necessary concentrations of the fluorine by performing a soot deposition process in a different environment from a consolidation process where the soot is sintered into a glass. Concentration of fluorine doped into the cladding layer enables obtaining a numerical aperture that confines a mono-mode of the fiber to resist bend-induced attenuation. Dimensions of the fiber further facilitate bending ability of the fiber. |
| FILED | Friday, May 04, 2007 |
| APPL NO | 11/744327 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/123 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805079 | Meyers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ronald E. Meyers (Columbia, Maryland); Keith S. Deacon (Columbia, Maryland) |
| ABSTRACT | Photonic signals are tagged with a pre-selected modification, such as a polarization signature to carry data across an obstructed path between sender and receiver. Communication authentication through polarization variation allows for Yuen-Kumar or entangled photon quantum communication protocols to propagate through environmental scattering media such as air, smoke, fog, rain, and water. While ultraviolet light photons are well suited as a carrier for quantum communication signals scattered in air, it is appreciated that visible wavelengths have longer propagation paths in water to convey non-line-of-sight data. A secure signal is scattered by the media and simultaneously communicated to a single recipient or multiple recipients exposed to scattered signal portions. A process of solving the scattering processes through a random scattering media is provided to reconstruct a quantum keyed message at a receiver. The scattering of the signal is utilized herein to provide non-line-of-sight and intentional short-range communication. |
| FILED | Monday, March 20, 2006 |
| APPL NO | 11/387085 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/118 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805183 | Keely et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Patricia Jo Keely (Madison, Wisconsin); Paolo P. Provenzano (Madison, Wisconsin); John Graham White (Madison, Wisconsin); Kevin William Eliceiri (Madison, Wisconsin) |
| ABSTRACT | The present invention provides methods and systems for evaluating biological materials for the diagnosis of disease, such as gland abnormalities, and the cancerous and precancerous conditions. Nonlinear optical microscopy techniques, such as MP microscopy and harmonic generation microscopy, are used to generate high resolution, three dimensional images of a test tissue, such as a biopsy tissue sample and tissue in whole organisms, that are analyzed, optionally in combination, to detect, identify and characterize tumor-associated collagen signatures. The presence, abundance and extent of histological features and structural motifs comprising tumor-associated collagen signatures may be directly and accurately correlated with the onset and progression of cancer, such as breast cancer. The present methods are capable of providing an accurate and selective diagnosis of cancer, and provide diagnostic information complementary to conventional diagnostic methods. |
| FILED | Thursday, June 21, 2007 |
| APPL NO | 11/766321 |
| ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805463 | Bevan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Laser-Scan, Inc. (Sterling, Virginia) |
| INVENTOR(S) | Timothy D. C. Bevan (Cambridge, United Kingdom); Michael J. Martin (Ashburn, Virginia); Paul J. Watson (Cambridge, United Kingdom) |
| ABSTRACT | This patent application is for a method and system that takes any arbitrary pre-existing geometric data and builds ISO 19107 compliant 3-Dimensional (3D) topology rather than requiring an incremental build of the topology. In accordance with at least one embodiment of the present invention, a method for integrating a three-dimensional feature geometry into a three-dimensional topology in a database includes adding a three-dimensional feature geometry into a table in a database; passing the three-dimensional feature geometry to a three-dimensional topology engine and a cache; performing a spatial refinement to determine a number of topology primitives in an existing three-dimensional geometry in the database that are near to topology primitives of the three-dimensional feature geometry; obtaining a number of relevant nearby spatial topology primitives in the geometries using a spatial search; performing an interaction refinement to determine a precise set of the number of relevant nearby topology primitives in the geometries that have spatial interactions; determining a common section of each topology primitive in the number of relevant nearby topology primitives that have spatial interactions; validating that the three-dimensional feature geometry fits into the three-dimensional topology table using a plurality of rules; and saving the validated three-dimensional feature geometry in the database. |
| FILED | Thursday, May 08, 2008 |
| APPL NO | 12/117576 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/803 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805476 | Hou |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Hsieh S. Hou (Rancho Palos Verdes, California) |
| ABSTRACT | A shared lossless Haar transform and an appended Haar transform are combined to form a lossless extended Haar transform in a pipeline architecture for providing fast lossless compressed data that is reversible. The extended Haar transform also provide intrinsic decorrelation for decorrelating corrected randomly generated numbers. |
| FILED | Monday, June 27, 2005 |
| APPL NO | 11/168981 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805498 | Elnozahy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Elmootazbellah Nabil Elnozahy (Austin, Texas); Peter Anthony Walker (Cedar Park, Texas) |
| ABSTRACT | An apparatus for providing remote access redirect in a host channel adapter of a system area network are provided. The apparatus provides a mechanism by which a host channel adapter, in response to receiving a marker message, places selected channel(s) of the host channel adapter in a remote access redirect (RAR) mode of operation. During the RAR mode of operation, memory access messages received by the host channel adapter that are destined for portions of an application memory space marked as being protected are converted to RAR receive messages and redirected to a queue pair associated with an operating system rather than the queue pair for the application. The operating system is responsible for serializing access to application memory pages outside of the host channel adapter. The mechanisms of the present invention may be used to perform a checkpoint data integrity operation. |
| FILED | Friday, December 19, 2008 |
| APPL NO | 12/339950 |
| ART UNIT | 2453 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/217 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE41762 | Lopez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Gabriel P. Lopez (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico); Linnea K. Ista (Albuquerque, New Mexico) |
| ABSTRACT | The present invention provides a nanostructured device comprising a substrate including nanotroughs therein; and a lipid bilayer suspended on or supported in the substrate. A separation method is also provided comprising the steps of supporting or suspending a lipid bilayer on a substrate; wherein the substrate comprises nanostructures and wherein the lipid bilayer comprises at least one membrane associated biomolecule; and applying a driving force to the lipid bilayer to separate the membrane associated biomolecule from the lipid bilayer and to drive the membrane associated biomolecule into the nanostructures. |
| FILED | Monday, June 30, 2008 |
| APPL NO | 12/215893 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Liquid purification or separation 210/632 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07802470 | Kotz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Savannah River Nuclear Solutions LLC (Aiken, South Carolina) |
| INVENTOR(S) | Dennis M. Kotz (North Augusta, South Carolina); William R. Hinz (Augusta, Georgia) |
| ABSTRACT | An ultrasonic liquid level detector for use within a shielded container, the detector being tubular in shape with a chamber at its lower end into which liquid from in the container may enter and exit, the chamber having an ultrasonic transmitter and receiver in its top wall and a reflector plate or target as its bottom wall whereby when liquid fills the chamber a complete medium is then present through which an ultrasonic wave may be transmitted and reflected from the target thus signaling that the liquid is at chamber level. |
| FILED | Wednesday, January 23, 2008 |
| APPL NO | 12/009993 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/290.V00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07803338 — Method and apparatus for combination catalyst for reduction of NOx in combustion products
| US 07803338 | Socha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ExonMobil Research and Engineering Company (Annandale, New Jersey); Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Richard F. Socha (Newtown, Pennsylvania); James C. Vartuli (Schwenksville, Pennsylvania); El-Mekki El-Malki (Princeton, New Jersey); Mohan Kalyanaraman (Media, Pennsylvania); Paul W. Park (Peoria, Illinois) |
| ABSTRACT | A method and apparatus for catalytically processing a gas stream passing therethrough to reduce the presence of NOx therein, wherein the apparatus includes a first catalyst composed of a silver containing alumina that is adapted for catalytically processing the gas stream at a first temperature range, and a second catalyst composed of a copper containing zeolite located downstream from the first catalyst, wherein the second catalyst is adapted for catalytically processing the gas stream at a lower second temperature range relative to the first temperature range. |
| FILED | Tuesday, June 21, 2005 |
| APPL NO | 11/157729 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry of inorganic compounds 423/239.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803419 | Barth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Abound Solar, Inc. (Loveland, Colorado) |
| INVENTOR(S) | Kurt L. Barth (Fort Collins, Colorado); Robert A. Enzenroth (Fort Collins, Colorado); Walajabad S. Sampath (Fort Collins, Colorado) |
| ABSTRACT | The present invention is directed to an apparatus and method for rapid cooling of a large substrate in a vacuum environment. A first cooled plate is brought into close proximity with one surface of a flat substrate. The spatial volume between the first cooling plate and the substrate is sealed and brought to a higher pressure than the surrounding vacuum level to increase the cooling efficiency. A second cooled plate is brought into close proximity with the opposite surface of the flat substrate. A second spatial volume between the second cooling plate and the substrate is sealed and the gas pressure is equalized to the gas pressure in the first spatial volume. The equalization of the gas pressure on both sides of the flat substrate eliminates deflection of the substrate and bending stress in the substrate. |
| FILED | Friday, September 22, 2006 |
| APPL NO | 11/525456 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803477 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Barbara R. Evans (Oak Ridge, Tennessee); Hugh M. O'Neill (Knoxville, Tennessee); Valerie Malyvanh Jansen (Memphis, Tennessee); Jonathan Woodward (Knoxville, Tennessee) |
| ABSTRACT | A method for the deposition of metals in bacterial cellulose and for the employment of the metallized bacterial cellulose in the construction of fuel cells and other electronic devices is disclosed. The method for impregnating bacterial cellulose with a metal comprises placing a bacterial cellulose matrix in a solution of a metal salt such that the metal salt is reduced to metallic form and the metal precipitates in or on the matrix. The method for the construction of a fuel cell comprises placing a hydrated bacterial cellulose support structure in a solution of a metal salt such that the metal precipitates in or on the support structure, inserting contact wires into two pieces of the metal impregnated support structure, placing the two pieces of metal impregnated support structure on opposite sides of a layer of hydrated bacterial cellulose, and dehydrating the three layer structure to create a fuel cell. |
| FILED | Friday, August 19, 2005 |
| APPL NO | 11/207431 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803493 | Bourgeois et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Richard Scott Bourgeois (Albany, New York); Sauri Gudlavalleti (Albany, New York); Shu Ching Quek (Clifton Park, New York); Wayne Charles Hasz (Pownal, Vermont); James Daniel Powers (Santa Monica, California) |
| ABSTRACT | A fuel cell assembly comprises a separating structure configured for separating a first reactant and a second reactant wherein the separating structure has an opening therein. The fuel cell assembly further comprises a fuel cell comprising a first electrode, a second electrode, and an electrolyte interposed between the first and second electrodes, and a passage configured to introduce the second reactant to the second electrode. The electrolyte is bonded to the separating structure with the first electrode being situated within the opening, and the second electrode being situated within the passage. |
| FILED | Wednesday, September 29, 2004 |
| APPL NO | 10/953756 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/460 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803529 | Cantor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sequenom, Inc. (San Diego, California) |
| INVENTOR(S) | Charles Cantor (Del Mar, California); Hubert Köster (La Jolla, California) |
| ABSTRACT | This invention relates to methods for detecting and sequencing target nucleic acid sequences, to mass modified nucleic acid probes and arrays of probes useful in these methods, and to kits and systems which contain these probes. Useful methods involve hybridizing the nucleic acids or nucleic acids which represent complementary or homologous sequences of the target to an array of nucleic acid probes. These probes comprise a single-stranded portion, an optional double-stranded portion and a variable sequence within the single-stranded portion. The molecular weights of the hybridized nucleic acids of the set can be determined by mass spectroscopy, and the sequence of the target determined from the molecular weights of the fragments. Nucleic acids whose sequences can be determined include DNA or RNA in biological samples such as patient biopsies and environmental samples. Probes may be fixed to a solid support such as a hybridization chip to facilitate automated molecular weight analysis and identification of the target sequence. |
| FILED | Tuesday, September 14, 1999 |
| APPL NO | 09/395409 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803594 | Read et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Buffalo, Office of Science and Tech Transfer (Amherst, New York) |
| INVENTOR(S) | Laurie K. Read (Orchard Park, New York); John Fisk (Amherst, New York) |
| ABSTRACT | The invention relates to enzymes in Trypanosoma brucei, and in particular, protein arginine methyltransferases. A unique, highly active recombinant arginine methyltransferase capable of monomethylation of peptides and proteins is described. |
| FILED | Thursday, August 06, 2009 |
| APPL NO | 12/536870 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803601 | Nobles, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas (Austin, Texas) |
| INVENTOR(S) | David R. Nobles, Jr. (Austin, Texas); R. Malcolm Brown, Jr. (Austin, Texas) |
| ABSTRACT | The present invention includes compositions and methods for making and using an isolated cyanobacterium that includes a portion of an exogenous bacterial cellulose operon sufficient to express bacterial cellulose, whereby the cyanobacterium produces extracellular glucose. The compositions and methods of the present invention may be used as a new global crop for the manufacture of cellulose, CO2 fixation, for the production of alternative sources of conventional cellulose as well as a biofuel and precursors thereof. |
| FILED | Wednesday, October 03, 2007 |
| APPL NO | 11/866872 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803623 | Caimi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | E.I. du Pont de Nemours and Company (Wilmington, Delaware); Alliance for Sustainable Energy LLC (Wilmington, Delaware) |
| INVENTOR(S) | Perry G. Caimi (Kennett Square, Pennsylvania); Yat-Chen Chou (Lakewood, Colorado); Mary Ann Franden (Centennial, Colorado); Kyle Knoke (Newark, Delaware); Luan Tao (Havertown, Pennsylvania); Paul V. Viitanen (West Chester, Pennsylvania); Min Zhang (Lakewood, Colorado); Yuying Zhang (New Hope, Pennsylvania) |
| ABSTRACT | Through screening of a Zymomonas mutant library the himA gene was found to be involved in the inhibitory effect of acetate on Zymomonas performance. Xylose-utilizing Zymomonas further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in medium comprising xylose and acetate. |
| FILED | Thursday, October 30, 2008 |
| APPL NO | 12/261166 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/471 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803737 | Coronado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Paul R. Coronado (Livermore, California); Sabre J. Coleman (Oakland, California); Robert D. Sanner (Livermore, California); Victoria L. Dias (Livermore, California); John G. Reynolds (San Ramon, California) |
| ABSTRACT | Solid materials have been developed to remove arsenic compounds from aqueous media. The arsenic is removed by passing the aqueous phase through the solid materials which can be in molded, granular, or powder form. The solid materials adsorb the arsenic leaving a purified aqueous stream. The materials are aerogels or xerogels and aerogels or xerogels and solid support structure, e.g., granulated activated carbon (GAC), mixtures. The species-specific adsorption occurs through specific chemical modifications of the solids tailored towards arsenic. |
| FILED | Friday, June 06, 2008 |
| APPL NO | 12/134700 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/338 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804029 | Tremblay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Paul L Tremblay (Idaho Falls, Idaho); Jill R Scott (Idaho Falls, Idaho) |
| ABSTRACT | A device and method for altering the line reactance of a transmission line having a transmission line, a first floating conductor and a grounding (shielding) conductor. The first floating conductor is positioned between and electrically insulated from the transmission line and the grounding conductor. A source and a load are connected at opposite ends of the transmission line. |
| FILED | Friday, December 05, 2008 |
| APPL NO | 12/329141 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Conductors and insulators 174/117.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804064 | Montaser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Akbar Montaser (Potomac, Maryland); Kaveh Jorabchi (Arlington, Virginia); Kaveh Kahen (Kleinburg, Canada) |
| ABSTRACT | A laser scattering based imaging technique is utilized in order to visualize the aerosol droplets in an inductively coupled plasma (ICP) torch from an aerosol source to the site of analytical measurements. The resulting snapshots provide key information about the spatial distribution of the aerosol introduced by direct and indirect injection devices: 1) a direct injection high efficiency nebulizer (DIHEN); 2) a large-bore DIHEN (LB-DIHEN); and 3) a PFA microflow nebulizer with a PFA Scott-type spray chamber. Moreover, particle image velocimetry (PIV) is used to study the in-situ behavior of the aerosol before interaction with, for example, plasma, while the individual surviving droplets are explored by particle tracking velocimetry (PTV). Further, the velocity distribution of the surviving droplets demonstrates the importance of the initial droplet velocities in complete desolvation of the aerosol for optimum analytical performance in ICP spectrometries. These new observations are important in the design of the next-generation direct injection devices for lower sample consumption, higher sensitivity, lower noise levels, suppressed matrix effects, and for developing smart spectrometers. For example, a controller can be provided to control the output of the aerosol source by controlling the configuration of the source or the gas flow rate via feedback information concerning the aerosol. |
| FILED | Monday, October 03, 2005 |
| APPL NO | 11/240642 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804147 | Tarsa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cree, Inc. (Goleta, California) |
| INVENTOR(S) | Eric Tarsa (Goleta, California); Thomas C. Yuan (Ventura, California); Maryanne Becerra (Santa Barbara, California); Praveen Yadev (Goleta, California) |
| ABSTRACT | A method for fabricating a light emitting diode (LED) package comprising providing an LED chip and covering at least part of the LED chip with a liquid encapsulant having a radius of curvature. An optical element is provided having a bottom surface with at least a portion having a radius of curvature larger than the liquid encapsulant. The larger radius of curvature portion of the optical element is brought into contact with the liquid encapsulant. The optical element is then moved closer to the LED chip, growing the contact area between said optical element and said liquid encapsulant. The liquid encapsulant is then cured. A light emitting diode comprising a substrate with an LED chip mounted to it. A meniscus ring is on the substrate around the LED chip with the meniscus ring having a meniscus holding feature. An inner encapsulant is provided over the LED chip with the inner encapsulant having a contacting surface on the substrate, with the meniscus holding feature which defines the edge of the contacting surface. An optical element is included having a bottom surface with at least a portion that is concave. The optical element is arranged on the substrate with the concave portion over the LED chip. A contacting encapsulant is included between the inner encapsulant and optical element. |
| FILED | Monday, July 31, 2006 |
| APPL NO | 11/496918 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/433 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804876 | Beach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Raymond J. Beach (Livermore, California); Ralph Page (Castro Valley, California); Thomas Soules (Livermore, California); Eddy Stappaerts (San Ramon, California); Sheldon Shao Quan Wu (Livermore, California) |
| ABSTRACT | In one embodiment, a laser oscillator is provided comprising an optical cavity, the optical cavity including a gain medium including an alkali vapor and a buffer gas, the buffer gas including 3He gas, wherein if 4He gas is also present in the buffer gas, the ratio of the concentration of the 3He gas to the 4He gas is greater than 1.37×10−6. Additionally, an optical excitation source is provided. Furthermore, the laser oscillator is capable of outputting radiation at a first frequency. In another embodiment, an apparatus is provided comprising a gain medium including an alkali vapor and a buffer gas including 3He gas, wherein if 4He gas is also present in the buffer gas, the ratio of the concentration of the 3He gas to the 4He gas is greater than 1.37×10−6. Other embodiments are also disclosed. |
| FILED | Wednesday, March 26, 2008 |
| APPL NO | 12/055408 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804928 | Nye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Jonathon Andrew Nye (Decatur, Georgia); Robert Jerome Nickles (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to targets, systems and methods for the cyclotron production of 124I from aluminum telluride (Al2Te3) targets. The systems and methods utilize low energy proton cyclotrons to produce 124I by the 124Te(p,n) reaction from enriched Al2Te3 glassy melts. The 124I is recovered in high yield from the glassy melt by adapted methods of common thermal distillation techniques. |
| FILED | Thursday, December 11, 2008 |
| APPL NO | 12/332691 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/195 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805010 | Posse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian Posse (Seattle, Washington); Antonio P Sanfilippo (Richland, Washington); Banu Gopalan (Cleveland, Ohio); Roderick M Riensche (Richland, Washington); Robert L Baddeley (Richland, Washington) |
| ABSTRACT | Quantification of the similarity between nodes in multiple electronic classification schemes is provided by automatically identifying relationships and similarities between nodes within and across the electronic classification schemes. Quantifying the similarity between a first node in a first electronic classification scheme and a second node in a second electronic classification scheme involves finding a third node in the first electronic classification scheme, wherein a first product value of an inter-scheme similarity value between the second and third nodes and an intra-scheme similarity value between the first and third nodes is a maximum. A fourth node in the second electronic classification scheme can be found, wherein a second product value of an inter-scheme similarity value between the first and fourth nodes and an intra-scheme similarity value between the second and fourth nodes is a maximum. The maximum between the first and second product values represents a measure of similarity between the first and second nodes. |
| FILED | Tuesday, July 25, 2006 |
| APPL NO | 11/493503 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/224 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805029 | Bayindir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mehmet Bayindir (Ankara, Turkey); Fabien Sorin (Cambridge, Massachusetts); Ayman F. Abouraddy (Boston, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Jeremy R. Arnold (Cambridge, Massachusetts); Yoel Fink (Brookline, Massachusetts); John D Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | There is provided a feedback-controlled self-heat-monitoring fiber, including an insulator having a fiber length with at least one metal-semiconductor-metal thermal sensing element along the fiber length and disposed at a position in a cross section of the fiber for sensing changes in fiber temperature. An electronic circuit is connected to the thermal sensing element for indicating changes in fiber temperature. A controller is connected for controlling optical transmission through an optical transmission element, that is disposed along the fiber length, in response to indications of changes in fiber temperature. |
| FILED | Thursday, March 05, 2009 |
| APPL NO | 12/380929 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805446 | Potok et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Thomas E. Potok (Oak Ridge, Tennessee); Joel W. Reed (Knoxville, Tennessee); Mark T. Elmore (Oak Ridge, Tennessee); Jim N. Treadwell (Louisville, Tennessee) |
| ABSTRACT | A computer method and system for storing, retrieving and displaying information has a multiplexing agent (20) that calculates a new document vector (25) for a new document (21) to be added to the system and transmits the new document vector (25) to master cluster agents (22) and cluster agents (23) for evaluation. These agents (22, 23) perform the evaluation and return values upstream to the multiplexing agent (20) based on the similarity of the document to documents stored under their control. The multiplexing agent (20) then sends the document (21) and the document vector (25) to the master cluster agent (22), which then forwards it to a cluster agent (23) or creates a new cluster agent (23) to manage the document (21). The system also searches for stored documents according to a search query having at least one term and identifying the documents found in the search, and displays the documents in a clustering display (80) of similarity so as to indicate similarity of the documents to each other. |
| FILED | Tuesday, October 12, 2004 |
| APPL NO | 10/963241 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/737 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805546 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota) |
| ABSTRACT | Methods, systems, and products are disclosed for chaining DMA data transfer operations for compute nodes in a parallel computer that include: receiving, by an origin DMA engine on an origin node in an origin injection FIFO buffer for the origin DMA engine, a RGET data descriptor specifying a DMA transfer operation data descriptor on the origin node and a second RGET data descriptor on the origin node, the second RGET data descriptor specifying a target RGET data descriptor on the target node, the target RGET data descriptor specifying an additional DMA transfer operation data descriptor on the origin node; creating, by the origin DMA engine, an RGET packet in dependence upon the RGET data descriptor, the RGET packet containing the DMA transfer operation data descriptor and the second RGET data descriptor; and transferring, by the origin DMA engine to a target DMA engine on the target node, the RGET packet. |
| FILED | Friday, July 27, 2007 |
| APPL NO | 11/829325 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital data processing systems: Input/output 710/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE41780 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Brian L. Anderson (Lodi, California); Bill W. Colston (San Ramon, California); Christopher J. Elkin (San Ramon, California) |
| ABSTRACT | A system for nucleic acid amplification of a sample comprises partitioning the sample into partitioned sections and performing PCR on the partitioned sections of the sample. Another embodiment of the invention provides a system for nucleic acid amplification and detection of a sample comprising partitioning the sample into partitioned sections, performing PCR on the partitioned sections of the sample, and detecting and analyzing the partitioned sections of the sample. |
| FILED | Friday, May 09, 2008 |
| APPL NO | 12/118418 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07802426 | Bollinger |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | SustainX, Inc. (West Lebanon, New Hampshire) |
| INVENTOR(S) | Benjamin R. Bollinger (Windsor, Vermont) |
| ABSTRACT | The invention relates to systems and methods for rapidly and isothermally expanding gas in a cylinder. The cylinder is used in a staged hydraulic-pneumatic energy conversion system and includes a gas chamber (pneumatic side) and a fluid chamber (hydraulic side) and a piston or other mechanism that separates the gas chamber and fluid chamber while allowing the transfer of force/pressure between each opposing chamber. The gas chamber of the cylinder includes ports that are coupled to a heat transfer subassembly that circulates gas from the pneumatic side and exchanges its heat with a counter flow of ambient temperature fluid from a reservoir or other source. |
| FILED | Tuesday, June 09, 2009 |
| APPL NO | 12/481235 |
| ART UNIT | 3748 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Power plants 060/508 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803405 | Keating et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Christine D. Keating (University Park, Pennsylvania); Marcus R. Helfrich (University Park, Pennsylvania); M. Scott Long (University Park, Pennsylvania); Lauren K. Mangeney-Slavin (University Park, Pennsylvania) |
| ABSTRACT | A means and method for preparing vesicles and freestanding two-dimensional assemblies using aqueous two-phase systems (ATPS) is described. The surface tension of the ATPS is sufficient to support the assembly of various types of particles, and provide the advantage of being biocompatible with DNA and other types of biological molecules that may be used in the assembly. Vesicles are formed by mixing chemically dissimilar compounds in appropriate concentrations and at a temperature sufficient to form a monophasic mixture. This mixture is then heated above the temperature at which the polymer mixture is monophasic, added to a lipid film, and allowed to hydrate at this elevated temperature. |
| FILED | Friday, May 16, 2003 |
| APPL NO | 10/439578 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/490 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803542 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yi Xiao (Goleta, California); Arica Lubin (Santa Barbara, California); Kevin Plaxco (Santa Barbara, California) |
| ABSTRACT | The invention provides a general “signal-on” architecture for oligonucleotide-based detectors that leads to order of magnitude increases in signal gain and sensitivity as compared to prior art detectors. The detectors of the invention rely on base pairing between two oligonucleotide strands, the sensor strand and the blocker strand. In the ‘off’ position of the detector, i.e., in the absence of target, the blocker strand and sensor strand are base-paired. As shown in FIG. 1, the formation of comparatively rigid, duplex DNA prevents the redox moiety from approaching the electrode surface, thereby suppressing Faradaic currents. When target is added to the system, the target displaces the blocker strand, binds to the sensor strand, liberating the end of the redox-labeled oligonucleotide to produce a flexible element. This, in turn, allows the redox moiety to collide with the electrode surface, producing a readily detectable Faradaic current. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 11/564674 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803556 | Bressan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Ray A. Bressan (W. Lafayette, Indiana); Meena L. Narasimhan (W. Lafayette, Indiana) |
| ABSTRACT | The Proteins of the PR-5 family having a lectin-like β barrel domain control apoptosis in yeast through receptor binding. Receptors that specifically bind to PR-5 proteins having a lectin-like β barrel domain have been found to be homologous to mammalian adiponectin receptors, and such PR-5 proteins can act as functional homologues of adiponectin and control adiponectin response in mammals. PR-5 proteins having a lectin-like β barrel domain, for example osmotin, can be used in the treatment of conditions in mammals which are the result of activation or inhibition of adiponectin receptor-mediated metaboloic pathways. PR-5 proteins having a lectin-like β barrel domain, nucleic acids encoding such proteins, and receptors that specifically bind such proteins, can also be used in screening and rational design of new therapeutic agents for use in mammals. |
| FILED | Wednesday, December 26, 2007 |
| APPL NO | 12/005236 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803568 | Wei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alexander Wei (West Lafayette, Indiana); Yan Zhao (West Lafayette, Indiana) |
| ABSTRACT | The present invention is directed to methods and products related to carbodithioate ligands bonded to surfaces. The invention is further directed to molecular and biomolecular sensing methods based on analyte recognition by carbodithioate ligands bonded to surfaces. |
| FILED | Thursday, April 20, 2006 |
| APPL NO | 11/407751 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.920 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803599 | Lutz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Barry R. Lutz (Seattle, Washington); Daniel T. Schwartz (Seattle, Washington) |
| ABSTRACT | A microfluidic fluid flow system (100) is disclosed having a fluid chamber or channel (150) with inlet and outlet ports (104, 106), allowing the fluid channel to be filled with a fluid. One or more flow obstructions or perturbances, such as cylinders (152), are provided in the channel. An oscillatory boundary condition is applied, for example, with a piezoelectric driver (130), that is selected to induce a conservative, low-intensity steady streaming flow in the channel. The low-intensity streaming flow produces distinct eddies that can be utilized, for example, for fluid-dynamically trapping or retaining particles (90) such as cells (92) at well defined locations in the channel. The system may be used to trap and study individual cells or for concentrating or filtering particles in a fluid. |
| FILED | Tuesday, January 18, 2005 |
| APPL NO | 11/038454 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/243 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803717 | Rawdanowicz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Thomas A. Rawdanowicz (Cary, North Carolina); Jagdish Narayan (Raleigh, North Carolina) |
| ABSTRACT | Epitaxial gallium nitride is grown on a silicon substrate while reducing or suppressing the formation of a buffer layer. The gallium nitride may be grown directly on the silicon substrate, for example using domain epitaxy. Alternatively, less than one complete monolayer of silicon nitride may be formed between the silicon and the gallium nitride. Subsequent to formation of the gallium nitride, an interfacial layer of silicon nitride may be formed between the silicon and the gallium nitride. |
| FILED | Thursday, October 21, 2004 |
| APPL NO | 10/970773 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/758 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803764 | Polt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Robin L. Polt (Tuscon, Arizona); Edward Bilsky (Biddeford, Maine) |
| ABSTRACT | Amphipathic glycopeptides, the amino acid sequence of which comprises an N-terminal opioid message sequence, a C-terminal helical address sequence, and a linker sequence between the message sequence and the helical address sequence, where the C-terminal helical address sequence has a length of nine amino acids, and at least one of the amino acid residues of the peptide is glycosylated. The peptides are useful for relieving pain, providing analgesia and treating anxiety, depression, obesity, anorexia nervosa, phobias, schizophrenia, Parkinson's disease and Alzheimer's disease. |
| FILED | Friday, March 25, 2005 |
| APPL NO | 10/594515 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803854 | Bressan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Ray A. Bressan (W. Lafayette, Indiana); Meena L. Narasimhan (W. Lafayette, Indiana) |
| ABSTRACT | The Proteins of the PR-5 family having a lectin-like β barrel domain control apoptosis in yeast through receptor binding. Receptors that specifically bind to PR-5 proteins having a lectin-like β barrel domain have been found to be homologous to mammalian adiponectin receptors, and such PR-5 proteins can act as functional homologues of adiponectin and control adiponectin response in mammals. PR-5 proteins having a lectin-like β barrel domain, for example osmotin, can be used in the treatment of conditions in mammals which are the result of activation or inhibition of adiponectin receptor-mediated metaboloic pathways. PR-5 proteins having a lectin-like β barrel domain, nucleic acids encoding such proteins, and receptors that specifically bind such proteins, can also be used in screening and rational design of new therapeutic agents for use in mammals. |
| FILED | Wednesday, December 26, 2007 |
| APPL NO | 12/005333 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Synthetic resins or natural rubbers 524/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803946 | Haley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael M. Haley (Eugene, Oregon); Darren W. Johnson (Eugene, Oregon); Orion B. Berryman (Eugene, Oregon); Charles A. Johnson (Eugene, Oregon); Calden N. Stimpson (Eugene, Oregon) |
| ABSTRACT | Disclosed herein is a class of tunable phenylacetylene compounds as well as compositions and methods for their use as host compounds for ligand binding. In certain examples the hosts report binding events by exhibiting altered spectroscopic properties, such as different fluorescent emission spectra. |
| FILED | Friday, December 14, 2007 |
| APPL NO | 11/957243 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/257 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804064 | Montaser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Akbar Montaser (Potomac, Maryland); Kaveh Jorabchi (Arlington, Virginia); Kaveh Kahen (Kleinburg, Canada) |
| ABSTRACT | A laser scattering based imaging technique is utilized in order to visualize the aerosol droplets in an inductively coupled plasma (ICP) torch from an aerosol source to the site of analytical measurements. The resulting snapshots provide key information about the spatial distribution of the aerosol introduced by direct and indirect injection devices: 1) a direct injection high efficiency nebulizer (DIHEN); 2) a large-bore DIHEN (LB-DIHEN); and 3) a PFA microflow nebulizer with a PFA Scott-type spray chamber. Moreover, particle image velocimetry (PIV) is used to study the in-situ behavior of the aerosol before interaction with, for example, plasma, while the individual surviving droplets are explored by particle tracking velocimetry (PTV). Further, the velocity distribution of the surviving droplets demonstrates the importance of the initial droplet velocities in complete desolvation of the aerosol for optimum analytical performance in ICP spectrometries. These new observations are important in the design of the next-generation direct injection devices for lower sample consumption, higher sensitivity, lower noise levels, suppressed matrix effects, and for developing smart spectrometers. For example, a controller can be provided to control the output of the aerosol source by controlling the configuration of the source or the gas flow rate via feedback information concerning the aerosol. |
| FILED | Monday, October 03, 2005 |
| APPL NO | 11/240642 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804281 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Shuo Wang (Blacksburg, Virginia); Fred Lee (Blacksburg, Virginia); Pengju Kong (Blacksburg, Virginia) |
| ABSTRACT | Common mode (CM) noise is substantially canceled in a switching power supply circuit such as a boost converter by providing a split inductor and analyzing the switching power supply circuit as a bridge circuit formed of the switch, portions of the split inductor and parasitic capacitances of respective portions of the power supply circuit. The bridge can then be balanced by addition of capacitance in parallel with the parasitic capacitance of a respective portion of the power supply circuit or dividing the split inductor such that a ratio of inductances of respective portions of the split inductor approximates a ratio of parasitic capacitances of the respective power supply circuit portions which may be measured or otherwise empirically determined. CM noise reduction of up to 40 db can be achieved without symmetric circuit design, addition of circuit elements or complex filtering having added cost, space requirements and power losses. Further, such a reduction in common mode noise allows simple EMI filtering arrangements to be employed further reducing cost and space requirements for the power supply circuit. |
| FILED | Wednesday, September 13, 2006 |
| APPL NO | 11/531392 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Power supply or regulation systems 323/222 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804998 | Mündermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Lars Mündermann (Mountain View, California); Stefano Corazza (San Francisco, California); Thomas P. Andriacchi (Los Altos Hills, California) |
| ABSTRACT | A markerless motion capture system is provided for measurements accurate enough for biomechanical, clinical, sport, entertainment, animation, game and movie, design, ergonomics, surveillance applications. The system has multiple cameras distributed around a viewing volume. The cameras allow for the creation of three-dimensional mesh representations of an object dynamically moving within the viewing volume. A model of the object that incorporates specific morphological and kinematic model information (including soft joint constraints) is then matched to the captured three-dimensional mesh representations. The matching routine aims to embed the model into each of the three-dimensional representations using (i) iterative closest point or simulated annealing algorithms and (ii) using soft joint constraints. This unique combination of routines offers a simple, time-efficient, accurate and thus more meaningful assessment of movements. The system further offers feasibility of accurately and precisely measuring three-dimensional kinematics of the dynamically moving object or human. |
| FILED | Friday, March 09, 2007 |
| APPL NO | 11/716130 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805029 | Bayindir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mehmet Bayindir (Ankara, Turkey); Fabien Sorin (Cambridge, Massachusetts); Ayman F. Abouraddy (Boston, Massachusetts); Ofer Shapira (Cambridge, Massachusetts); Jeremy R. Arnold (Cambridge, Massachusetts); Yoel Fink (Brookline, Massachusetts); John D Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | There is provided a feedback-controlled self-heat-monitoring fiber, including an insulator having a fiber length with at least one metal-semiconductor-metal thermal sensing element along the fiber length and disposed at a position in a cross section of the fiber for sensing changes in fiber temperature. An electronic circuit is connected to the thermal sensing element for indicating changes in fiber temperature. A controller is connected for controlling optical transmission through an optical transmission element, that is disposed along the fiber length, in response to indications of changes in fiber temperature. |
| FILED | Thursday, March 05, 2009 |
| APPL NO | 12/380929 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805518 | Kamvar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Sepandar D. Kamvar (San Francisco, California); Mario T. Schlosser (Hochhein am Main, Germany) |
| ABSTRACT | Methods to minimize the impact of malicious peers on the performance of a peer-to-peer system. The system computes a global trust value for a peer by calculating the left principal eigenvector of a matrix of normalized local trust values, thus taking into consideration the entire system's history with each single peer. Algorithms for performing such computations in a scalable and distributed manner are provided. Rewarding highly reputable peers with better quality of service encourages non-malicious peers to share more information and to self-police their own information. |
| FILED | Monday, November 15, 2004 |
| APPL NO | 10/989293 |
| ART UNIT | 2464 — Multiplex and VoIP |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/227 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07802923 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | AB Sciex LLC (Framingham, Massachusetts) |
| INVENTOR(S) | Don W. Arnold (Livermore, California); Kenneth R. Hencken (Pleasanton, California); Sammy S. Datwani (Dublin, United Kingdom); Patrick Pak-Ho Leung (Belmont, China PRC); Douglas R. Cyr (Livermore, California); Jason E. Rehm (Alameda, California) |
| ABSTRACT | A junction is made between a first microfluidic substrate (12) having an elongate component (303) protruding from it and a second microfluidic substrate (22) having a corresponding conduit (261). Each of the substrates has a pair of alignment features, for example planar orthogonal surfaces (13,15; 23,25) or grooves (141,151; 241, 251) in opposite sides of the substrate. The substrates are placed on an alignment jig 6 having location features (63, 65) corresponding to the alignment features. The elongate component can be surrounded by a compressible gasket 40). The substrates are pushed towards each other so that the elongate component enters the conduit and the gasket, if any, is compressed. A fluid-tight junction results so long as the substrates are maintained in the necessary position, either by permanent means, or, if a junction which can be disassembled is needed, by maintaining pressure between the substrates. Novel apparatus and novel microfluidic assemblies, including microfluidic chips having grooves in their sides, are described. |
| FILED | Friday, April 01, 2005 |
| APPL NO | 10/599591 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803125 | Santos-Munne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Rehabilitation Institute of Chicago Enterprises (Chicago, Illinois) |
| INVENTOR(S) | Julio Santos-Munne (Glenview, Illinois); Alex Makhlin (Chicago, Illinois); Ela Lewis (Chicago, Illinois); Michael Peshkin (Evanston, Illinois); David A. Brown (Evanston, Illinois); J. Edward Colgate (Evanston, Illinois); James L. Patton (Wilmette, Illinois); Benjamin L. Rush (Evanston, Illinois); Doug Schwandt (Palo Alto, California) |
| ABSTRACT | A pelvic support unit is coupled to a base by a powered vertical force actuator mechanism. A torso support unit, which is affixed to the patient independently of the pelvic support unit, is connected to the base by one or more powered articulations which are actuable around respective axes of motion. Sensors sense the linear and angular displacement of the pelvic support unit and the torso support unit. A control unit is coupled to these sensors and, responsive to signals from them, selectively control the displacement actuator and articulation(s). |
| FILED | Tuesday, June 09, 2009 |
| APPL NO | 12/481222 |
| ART UNIT | 3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery: Kinesitherapy 61/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803885 | Brennan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Dow Global Technologies Inc. (Midland, Michigan) |
| INVENTOR(S) | David J. Brennan (Midland, Michigan); Dean M. Welsh (Midland, Michigan); Yu Chen (Midland, Michigan); Jeff M. Shaw (Saginaw, Michigan) |
| ABSTRACT | The present invention relates to a pentathienyl-fluorene copolymer having structural units represented by formula (I): here R and R′ are each independently a substituent or H. The invention also relates to a transistor containing this copolymer. The present invention addresses a problem in the art by providing an electroactive device with exceptionally low hysteresis. |
| FILED | Tuesday, March 01, 2005 |
| APPL NO | 10/592872 |
| ART UNIT | 1796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Synthetic resins or natural rubbers 525/535 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804090 | Wong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | William Wong (San Carlos, California); Rene Lujan (Sunnyvale, California); Eugene Chow (Fremont, California) |
| ABSTRACT | A self-aligned, thin-film, top-gate transistor and method of manufacturing same are disclosed. A first print-patterned mask is formed over a metal layer by digital lithography, for example by printing with a phase change material using a droplet ejector. The metal layer is then etched using the first print-patterned mask to form source and drain electrodes. A semiconductive layer and an insulative layer are formed thereover. A layer of photosensitive material is then deposited and exposed through the substrate, with the source and drain electrodes acting as masks for the exposure. Following development of the photosensitive material, a gate metal layer is deposited. A second print-patterned mask is then formed over the device, again by digital lithography. Etching and removal of the photosensitive material leaves the self-aligned top-gate electrode. |
| FILED | Wednesday, January 23, 2008 |
| APPL NO | 12/018794 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804656 | Gomez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Seagate Technology LLC (Scotts Valley, California) |
| INVENTOR(S) | Kevin Arthur Gomez (Wexford, Pennsylvania); William Albert Challener (Sewickley, Pennsylvania); Ravishankar Ajjanagadde Shivarama (Bloomington, Minnesota); Patrick Breckow Chu (Wexford, Pennsylvania) |
| ABSTRACT | An apparatus includes a load beam, a slider coupled to the load beam by a gimbal assembly and including an optical transducer, an optical fiber for transmitting light directly toward the transducer, and a mounting structure for adjusting the position of an end of the optical fiber. Data storage devices that include the apparatus are also included. |
| FILED | Wednesday, February 06, 2008 |
| APPL NO | 12/026683 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Dynamic magnetic information storage or retrieval 360/59 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07802752 | Papamoschou |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Dimitri Papamoschou (Mission Viejo, California) |
| ABSTRACT | An embodiment of the invention is a technique to suppress noise in a jet engine. A substantially annular fan nozzle is attached to a pylon and discharges a fan stream into atmosphere from an aft end thereof. A core nozzle discharges core stream into the atmosphere. The core nozzle has an exterior surface. A stream director is mounted on the pylon to direct the fan stream away from the pylon. At least a portion of the stream director is situated outside the aft end to maintain substantially constant flow area of the fan nozzle. |
| FILED | Friday, December 29, 2006 |
| APPL NO | 11/648094 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/1.N00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07802756 | Kendall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | AeroVironment Inc. (Monrovia, California) |
| INVENTOR(S) | Greg T. Kendall (Glendale, California); Walter R. Morgan (Simi Valley, California) |
| ABSTRACT | A span-loaded, highly flexible flying wing, having horizontal control surfaces mounted aft of the wing on extended beams to form local pitch-control devices. Each of five spanwise wing segments of the wing has one or more motors and photovoltaic arrays, and produces its own lift independent of the other wing segments, to minimize inter-segment loads. Wing dihedral is controlled by separately controlling the local pitch-control devices consisting of a control surface on a boom, such that inboard and outboard wing segment pitch changes relative to each other, and thus relative inboard and outboard lift is varied. |
| FILED | Monday, April 02, 2007 |
| APPL NO | 11/732109 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/45.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07802799 | Semmes |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Edmund B. Semmes (Madison, Alabama) |
| ABSTRACT | A method is provided for joining a metallic member to a structure made of a composite matrix material. One or more surfaces of a portion of the metallic member that is to be joined to the composite matrix structure is provided with a plurality of outwardly projecting studs. The surface including the studs is brought into engagement with a portion of an uncured composite matrix material so that fibers of the composite matrix material intertwine with the studs, and the metallic member and composite structure form an assembly. The assembly is then companion cured so as to join the metallic member to the composite matrix material structure. |
| FILED | Monday, September 18, 2006 |
| APPL NO | 11/527653 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Seal for a joint or juncture 277/627 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804600 | Smith |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | David D. Smith (Huntsville, Alabama) |
| ABSTRACT | A ring-laser gyroscope system includes a ring-laser gyroscope (RLG) and at least one dispersive element optically coupled to the RLG's ring-shaped optical path. Each dispersive element has a resonant frequency that is approximately equal to the RLG's lasing frequency. A group index of refraction defined collectively by the dispersive element(s) has (i) a real portion that is greater than zero and less than one, and (ii) an imaginary portion that is less than zero. |
| FILED | Friday, March 07, 2008 |
| APPL NO | 12/044740 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/459 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805276 | Byers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Terry Byers (League City, Texas); Frank L. Gibbons (Houston, Texas); Eric L. Christiansen (Houston, Texas) |
| ABSTRACT | In an embodiment, an apparatus and method capable of determining the time and location of a projectile's impact is disclosed. In another embodiment, an apparatus and method capable of determining the time and location of a projectile's impact as well as the direction from whence the projectile came is disclosed. |
| FILED | Tuesday, December 18, 2007 |
| APPL NO | 11/958937 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07803597 | Savary et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Brett J. Savary (Jonesboro, Arkansas); Randall G. Cameron (Thonotosassa, Florida); Gary A. Luzio (Winter Haven, Florida); Thomas G. McCollum (Vero Beach, Florida); Prasanna Vasu (Jonesboro, Arkansas); Alberto Nunez (Dresher, Pennsylvania) |
| ABSTRACT | Enzymes accumulated in plant cell walls serve diverse physiological functions including metabolism, polysaccharide structure modification, and molecular communication in interactions with other organisms. Pectin methylesterases are economically important enzymes for their impact on quality and processing properties of fruit and vegetable food products. We have now purified TT-PME to homogeneity from sweet orange finisher pulp and determined the complete corresponding nucleic acid sequence. Purified TT-PME was observed by SDS-PAGE as two doublet bands with molecular masses of approximately 46,000 Da and 56,000 Da. Direct Edman sequencing from these proteins showed a common N-terminal peptide. De novo sequencing of eight TT-PME tryptic peptides determined by MALDI-TOF/TOF mass spectrometry provided additional internal sequences. TT-PME did not correspond to any previously reported Citrus spp. PME sequence. Our results show Citrus TT-PME is a distinctive new isoform with phylogenetic relationship closer to PME isoforms in other species rather than to previously described Citrus PME genes. |
| FILED | Tuesday, November 20, 2007 |
| APPL NO | 11/986187 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/197 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07803919 | Seroussi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Eyal Seroussi (Shaarey Tiqwa, Israel); Harris A. Lewin (Champaign, Illinois); Mark R. Band (Savoy, Illinois); Miri Cohen-Zinder (Moshav Kfar Bilu, Israel); James K. Drackley (Champaign, Illinois); Denis M. Larkin (Savoy, Illinois); Juan J. Loor (Urbana, Illinois); Micha Ron (Nes-Ziona, Israel); Moshe Shani (Macabim, Israel); Joel Ira Weller (Rehovot, Israel) |
| ABSTRACT | A quantitative trait locus (QTL) affecting milk fat and protein concentration was localized to a 4cM confidence interval on chromosome 6 centered on the microsatellite BM143. The genes and sequence variation in this region were characterized, and common haplotypes spanning five polymorphic sites in the genes IBSP, SPP1, PKD2, and ABCG2 for two sires heterozygous for this QTL were localized. Expression of SPP1 and ABCG2 in the bovine mammary gland increased from parturition through lactation. SPP1 was sequenced, and all the coding exons of ABCG2 and PKD2 were sequenced for these two sires. The single nucleotide change capable of encoding a substitution of tyrosine-581 to serine (Y581S) in the ABCG2 transporter was the only polymorphism corresponding to the segregation status of all three heterozygous and 15 homozygous sires for the QTL in the Israeli and US Holstein populations. |
| FILED | Wednesday, June 28, 2006 |
| APPL NO | 11/427230 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP21347 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Greenwood, Florida) |
| INVENTOR(S) | Zhanao Deng (Ellenton, Florida); Brent Harbaugh (Bradenton, Florida) |
| ABSTRACT | A new Caladium plant named ‘UF340’ particularly distinguished by its large number of wide lance leaves having a large, bright, and pure white center surrounded by green margins, and demonstrated potential to produce attractive plants in outdoor landscapes, and produce attractive pot plants when tubers are forced in containers, is disclosed. |
| FILED | Tuesday, March 24, 2009 |
| APPL NO | 12/383382 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 07804048 | Furman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Bruce K. Furman (Poughguag, New York); Yves Martin (Ossining, New York); Theodore G. van Kessel (Millbrook, New York) |
| ABSTRACT | An apparatus for cooling a surface having a metal structure made of a material with high thermal conductivity, and designed to provide efficient cooling of the surface while minimizing mechanical stress between the metal structure and the surface. |
| FILED | Tuesday, September 04, 2007 |
| APPL NO | 11/849672 |
| ART UNIT | 3742 — Electrical Circuits and Systems |
| CURRENT CPC | Electric heating 219/497 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804961 | Mauro, II et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | QUALCOMM Incorporated (San Diego, California) |
| INVENTOR(S) | Anthony Patrick Mauro, II (San Diego, California); Magdalena Espelien (San Diego, California) |
| ABSTRACT | A method and apparatus for fast generation of a cryptographic key. A processor within a wireless communication device generates a public key upon termination of wireless communication. When a user of the wireless communication device desires to initiate a secure communication subsequent to the previous communication, the public key that was generated upon termination of the previous communication is used to engage in secure communications with a second communication device. |
| FILED | Wednesday, December 19, 2001 |
| APPL NO | 10/029639 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Cryptography 380/270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805291 | Berkowitz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Sidney Berkowitz (Baltimore, Maryland) |
| ABSTRACT | A method of identifying a topic of a text. Text is received. Then, the nouns in the text are identified. The singular form of each identified noun is determined. Combinations are created of the singular form of the identified nouns, where the number of singular forms of the nouns in the combinations is user-definable. The frequency of occurrence in the text of each noun that corresponds to its singular form is determined. Each frequency of occurrence is assigned as a score to its corresponding singular form noun. Each combination of singular form nouns is assigned a score that is equal to the sum of the scores of its constituent singular form nouns. The user-definable number of top scoring singular form nouns and combinations of singular form nouns are selected as the topic of the text. |
| FILED | Wednesday, May 25, 2005 |
| APPL NO | 11/137594 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07803530 | Cohenford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cytyc Corporation (Marlborough, Massachusetts) |
| INVENTOR(S) | Menashi A. Cohenford (West Warwick, Rhode Island); Brian Lentrichia (Acton, Massachusetts) |
| ABSTRACT | The invention provides methods for detection and typing of HPV infection using PNA probes. More specifically, methods are provided for detecting high-risk types of HPV infection with minimal numbers of PNA probes or using PNA probes to selectively amplify only high-risk types of HPV. |
| FILED | Wednesday, December 18, 2002 |
| APPL NO | 10/323188 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07805463 | Bevan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Laser-Scan, Inc. (Sterling, Virginia) |
| INVENTOR(S) | Timothy D. C. Bevan (Cambridge, United Kingdom); Michael J. Martin (Ashburn, Virginia); Paul J. Watson (Cambridge, United Kingdom) |
| ABSTRACT | This patent application is for a method and system that takes any arbitrary pre-existing geometric data and builds ISO 19107 compliant 3-Dimensional (3D) topology rather than requiring an incremental build of the topology. In accordance with at least one embodiment of the present invention, a method for integrating a three-dimensional feature geometry into a three-dimensional topology in a database includes adding a three-dimensional feature geometry into a table in a database; passing the three-dimensional feature geometry to a three-dimensional topology engine and a cache; performing a spatial refinement to determine a number of topology primitives in an existing three-dimensional geometry in the database that are near to topology primitives of the three-dimensional feature geometry; obtaining a number of relevant nearby spatial topology primitives in the geometries using a spatial search; performing an interaction refinement to determine a precise set of the number of relevant nearby topology primitives in the geometries that have spatial interactions; determining a common section of each topology primitive in the number of relevant nearby topology primitives that have spatial interactions; validating that the three-dimensional feature geometry fits into the three-dimensional topology table using a plurality of rules; and saving the validated three-dimensional feature geometry in the database. |
| FILED | Thursday, May 08, 2008 |
| APPL NO | 12/117576 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/803 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 07802337 | van Roosmalen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Marshall Elevator Company (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Linda van Roosmalen (Verona, Pennsylvania); Francis S. Glogowski (Cranberry Township, Pennsylvania); David A. Heiner (Pittsburgh, Pennsylvania); Robert S. Jamison, III (Pittsburgh, Pennsylvania); Peter D. Horvath (Brownsville, Pennsylvania); Steven Walker (Peters Township, Pennsylvania) |
| ABSTRACT | A ramp assembly includes an elongated frame sized and shaped to extend between a first door and a second door aligned opposite each other on opposed sides of a vehicle; a first sectional ramp section having a first end and a second end; and a second sectional ramp having a first end and a second end. The first sectional ramp is slidably moveable along the frame from a stored position to a deployed position on either of the opposed sides of the vehicle. The second sectional ramp is positioned adjacent the first sectional ramp and is slidably moveable along the frame from a stored position to a deployed position on either of the opposed sides of the vehicle. The ramp assembly also includes a first locking mechanism coupled to the first end of each of the first sectional ramp and the second sectional ramp; and a second locking mechanism coupled to the second end of each of the first sectional ramp and the second sectional ramp. The first locking mechanism is placed in a locked position and the second locking mechanism is placed in an unlocked position to allow the first and second sectional ramps to be coupled together and moved from the stored position to the deployed position through the first door. The second locking mechanism is placed in a locked position and the first locking mechanism is placed in an unlocked position to allow the first and second sectional ramps to be coupled together and moved from the stored position to the deployed position through the second door. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 11/928481 |
| ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Bridges 014/69.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Federal Reserve Bank (FED)
| US 07802717 | Mueller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Federal Reserve Bank of Dallas (Dallas, Texas); Federal Reserve Bank of Kansas City (Kansas City, Missouri); Federal Reserve Bank of Atlanta (Atlanta, Georgia); Federal Reserve Bank of Cleveland (Cleveland, Ohio) |
| INVENTOR(S) | Randall Lee Mueller (Kansas City, Missouri); Thomas Edwin Schaadt (Westerville, Ohio); Steven Joseph Harris (Worthington, Ohio); Eric Lendl (Bedford, Texas); V. Srinivas Nori (Norcross, Georgia); Steven Q. Purser (Plano, Texas) |
| ABSTRACT | Monitoring an electronic check processing status of an image cash letter (“ICL”) and items in the ICL includes processing each ICL item by performing at least one electronic check processing event in connection with the item. For each electronic check processing event and for each item, a record comprising information related to a status of the electronic check processing event is created. Each record is associated with the corresponding item and the ICL. A status of each item can be determined based on the information stored in the records corresponding to that item. A status of the ICL can be determined based on the status of the items from the ICL. |
| FILED | Friday, July 07, 2006 |
| APPL NO | 11/482360 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Registers 235/379 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 07805446 | Potok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Thomas E. Potok (Oak Ridge, Tennessee); Joel W. Reed (Knoxville, Tennessee); Mark T. Elmore (Oak Ridge, Tennessee); Jim N. Treadwell (Louisville, Tennessee) |
| ABSTRACT | A computer method and system for storing, retrieving and displaying information has a multiplexing agent (20) that calculates a new document vector (25) for a new document (21) to be added to the system and transmits the new document vector (25) to master cluster agents (22) and cluster agents (23) for evaluation. These agents (22, 23) perform the evaluation and return values upstream to the multiplexing agent (20) based on the similarity of the document to documents stored under their control. The multiplexing agent (20) then sends the document (21) and the document vector (25) to the master cluster agent (22), which then forwards it to a cluster agent (23) or creates a new cluster agent (23) to manage the document (21). The system also searches for stored documents according to a search query having at least one term and identifying the documents found in the search, and displays the documents in a clustering display (80) of similarity so as to indicate similarity of the documents to each other. |
| FILED | Tuesday, October 12, 2004 |
| APPL NO | 10/963241 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/737 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 07803908 | Depre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Christophe Depre (New York, New York); Stephen F. Vatner (New York, New York) |
| ABSTRACT | The present invention provides novel nucleic acid and protein sequences for methods and compositions for treating, screening, and diagnosing cardiovascular disease and methods for using these genes and gene products for prevention of cardiac cell death and prevention of cardiac tissue damage resulting from ischemic events in cardiac tissue, as well as other tissue that is subject to damage resulting from an ischemic event. The genes, gene products and agents of the invention are also useful for treating other related clinical or coronary events such as angina, myocardial infarct (MI), and stroke, for monitoring the effectiveness of their treatment, and for drug development. The genes, gene products and agents of the present invention are also provided as pharmaceutical compositions for treatment of cardiovascular disease, ischemic heart disease, myocardial infarct and related conditions. Kits are also provided for the diagnosis, treatment and prognosis of cardiac diseases and related conditions. |
| FILED | Wednesday, March 01, 2006 |
| APPL NO | 11/365484 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 07802672 | Schimmel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Todd M Schimmel (Annandale, Virginia); Thomas C Potter (Oak Hill, Virginia) |
| ABSTRACT | A diverter gate generally includes a bracket which connects to an actuator and a flag which releasably engages with the bracket via cooperating engagement members. The cooperating engagement members may be symmetrical, and may comprise one or more tabs and one or more corresponding receptacles. The tabs may be dimensioned slightly larger than the receptacles so as to create a positive interference fit. The bracket and the flag may include openings to receive a fastener extending substantially across the length of the gate. Tightening the fastener compresses the tab(s) against the receptacle(s) to result in a compression fit between the flag and the bracket. The two-piece design allows the flag to be easily removed and reversed or replaced, without disassembling or removing the bracket or the actuator. |
| FILED | Tuesday, September 11, 2007 |
| APPL NO | 11/853587 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Conveyors: Power-driven 198/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07803984 | Trick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Harold N. Trick (Olsburg, Kansas); Judith L. Roe (Manhattan, Kansas); Timothy C. Todd (Manhattan, Kansas); Michael A. Herman (Manhattan, Kansas) |
| ABSTRACT | The present invention relates to compositions and methods for controlling nematode infestation of plants. In particular, the present invention provides vectors comprising sequences designed to control nematodes by RNA interference (RNAi) and transgenic plants transformed with such vectors. |
| FILED | Wednesday, July 09, 2003 |
| APPL NO | 10/616390 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/279 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07804873 | Liu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences (Changchun, China PRC) |
| INVENTOR(S) | Xingyuan Liu (Changchun, China PRC) |
| ABSTRACT | Electrically pumped surface emitting organic laser device having a multi-layer of organic materials disposed between a highly reflective microcavity mirror and a highly reflective mirror to thereby form a coupled microcavity. More specifically, the organic laser device includes a substrate; a bottom mirror over the substrate; a layer of spacer over the bottom mirror; a coupling mirror over the spacer layer; an anode over the coupling mirror; an active layer over the anode; a cathode over the active layer; and a top mirror over the cathode. The combination of the electrode and the mirror leads to low optical absorption and highly reflective electrical contacts at organic-electrode interfaces. Electroluminescent emission efficiency is improved due to the realization of efficient electron-injection and hole-injection. A low loss organic laser device with a coupled microcavity structure is realized that can produce surface emitting laser output under electrical pumping. |
| FILED | Wednesday, December 12, 2007 |
| APPL NO | 12/001740 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/50.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 28, 2010.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20100928.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page