FedInvent™ Patents

Patent Details for Tuesday, November 02, 2010 

This page was updated on Monday, March 27, 2023 at 01:55 AM GMT

Department of Defense (DOD) 

US 07823283 Hougham et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Gareth G. Hougham (Ossining, New York);  Brian S. Beaman (Cary, North Carolina);  Evan G. Colgan (Chestnut Ridge, New York);  Paul W. Coteus (Yorktown, New York);  Stefano S. Oggioni (Besana in Brianza, Italy);  Enrique Vargas (Bronx, New York)
ABSTRACT A land grid array (LGA) interposer structure, including an electrically insulating carrier plane, and at least one interposer mounted on a first surface of said carrier plane. The interposer possesses a hemi-toroidal configuration in transverse cross-section and is constituted of a dielectric elastomeric material. A plurality of electrically-conductive elements are arranged about the surface of the at least one hemi-toroidal interposer and extend radically inwardly and downwardly from an uppermost end thereof into electrical contact with at least one component located on an opposite side of the electrically insulating carrier plane. Provided is also a method of producing the land grid array interposer structure.
FILED Friday, February 15, 2008
APPL NO 12/032316
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/884
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US 07823498 Schneider et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John Schneider (Huntingburg, Indiana);  Christopher Brown (Bloomington, Indiana);  Robin Cromwell (Mitchell, Indiana);  Donald Lowe (San Antonio, Texas)
ABSTRACT A protective structure for a vehicle having an opening on an upper surface is provided. One embodiment of the invention has at least a partial enclosure around an area defined laterally by the vehicle opening with an overhead and side protective capability. An embodiment of the invention has an overhead cover that is formed to substantially enclose a top area of the enclosure and having multiple panels that may be locked into place or opened by an occupant for exit through a top area of the enclosure. The multiple panels in this embodiment extend upwardly and inwardly from a section of the enclosure's side walls. Ballistic windows are provided on the protective structure such that an occupant can view laterally and vertically through the enclosure and overhead cover. A shield or protective plate can be mounted on one side of the enclosure.
FILED Saturday, November 10, 2007
APPL NO 11/998977
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/36.80
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US 07823839 Glezer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Ari Glezer (Atlanta, Georgia);  Michael Edward DeSalvo (Smyrna, Georgia)
ABSTRACT Systems and methods for modifying fluid flowing over solid bodies are provided. A representative system incorporates a vorticity concentration-producing component and a synthetic jet actuator. The vorticity concentration-producing component is disposed on a pressure side of the solid body. The fluid flowing over the solid body remains attached to a surface of the solid body in a vicinity of the vorticity concentration-producing component. The synthetic jet actuator includes a jet housing that incorporates an internal chamber with a volume of fluid and an opening in the jet housing connecting the internal chamber to an external environment having the fluid. The synthetic jet actuator is operative to periodically change the volume within the internal chamber such that a synthetic jet stream comprising a series of fluid vortices is generated and projected in the external environment out from the opening of the jet housing resulting in a reduction in pressure drag of the solid body compared to the pressure drag exhibited by the solid body without operation of the synthetic jet actuator.
FILED Monday, October 31, 2005
APPL NO 11/263504
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/204.100
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US 07823866 Pluymers et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Brian A. Pluymers (Haddonfield, New Jersey);  Khanh Nguyen (Conshohocken, Pennsylvania)
ABSTRACT An arrangement for clamping a flat plate to a flat surface includes juxtaposing the plate to the flat surface. An axially-movable wedging element defining a surface fitted with wedges is fixed against motion in other than a direction of elongation, and is forced to move in the direction of elongation. The wedges are forced against a first spring beam to impart forces thereto. The forces are coupled from the first spring beam to a second spring beam by intermediary supports. The second spring beam bears against a surface of the flat plate to force the plate against the flat surface.
FILED Friday, September 28, 2007
APPL NO 11/864033
ART UNIT 3727 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Work holders
269/254.CS0
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US 07824098 Melamud et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Renata Melamud (Palo Alto, California);  Bongsang Kim (Albany, California);  Matthew Hopcroft (San Francisco, California);  Saurabh Chandorkar (Stanford, California);  Manu Agarwal (Stanford, California);  Thomas W. Kenny (San Carlos, California)
ABSTRACT Mechanical transducers such as pressure sensors, resonators or other frequency-reference devices are implemented under conditions characterized by different temperatures. According to an example embodiment of the present invention, a combination of materials is implemented for mechanical transducer applications to mitigate temperature-related changes at or near a selected turnover temperature. In one application, a material property mismatch is used to facilitate single-anchor transducer applications, such as for resonators. Another application is directed to a Silicon-Silicon dioxide combination of materials.
FILED Monday, January 21, 2008
APPL NO 12/017228
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Thermal measuring and testing
374/117
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US 07824129 Ghosh et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Menzie-Cura and Associates, Inc. (Severna Park, Maryland);  University of Maryland, Baltimore County (Baltimore, Maryland)
INVENTOR(S) Upal Ghosh (Ellicott City, Maryland);  Charles A. Menzie (Severna Park, Maryland);  Craig B. Amos (Westford, Massachusetts)
ABSTRACT An agglomerate for use in economical bulk treatment of contaminated sediments with minimal environmental impact is formed from a sorbent, bentonite clay and sand. The agglomerate has sufficient density so as to sink through a water column into sediment below the water column and is still sufficiently light as to be capable of mixing with the sediment when subjected only to bioturbation. The agglomerate can be formed into pellets and applied to a water column over contaminated sediment by broadcast methods, so as to permit economical remediation of contaminated sediment with negligible environmental impact.
FILED Wednesday, October 17, 2007
APPL NO 11/873835
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Hydraulic and earth engineering
45/128.100
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US 07824158 Bauer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Randall Charles Bauer (Loveland, Ohio);  D. Keith Patrick (Cincinnati, Ohio)
ABSTRACT A turbine blade damper includes an outer part for damping vibration of the blade airfoil and a supporting inner part. The two parts are formed of different materials for the different performance required thereof in the blade.
FILED Monday, June 25, 2007
APPL NO 11/767548
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/232
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US 07824466 Vanheusden et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Cabot Corporation (Boston, Massachusetts)
INVENTOR(S) Karel Vanheusden (Los Altos, California);  Klaus Kunze (Albuquerque, New Mexico);  Hyungrak Kim (Albuquerque, New Mexico);  Aaron D. Stump (Albuquerque, New Mexico);  Allen B. Schult (Albuquerque, New Mexico);  Mark J. Hampden-Smith (Albuquerque, New Mexico);  Chuck Edwards (Rio Rancho, New Mexico);  Anthony R. James (Rio Rancho, New Mexico);  James Caruso (Albuquerque, New Mexico);  Toivo T. Kodas (Albuquerque, New Mexico);  Scott T. Haubrich (Albuquerque, New Mexico);  Mark H. Kowalski (Albuquerque, New Mexico);  Nathan E. Stott (Suwon, South Korea)
ABSTRACT Processes for the production of metal nanoparticles. In one aspect, the invention is to a process comprising the steps of mixing a heated first solution comprising a base and/or a reducing agent (e.g., a non-polyol reducing agent), a polyol, and a polymer of vinyl pyrrolidone with a second solution comprising a metal precursor that is capable of being reduced to a metal by the polyol. In another aspect, the invention is to a process that includes the steps of heating a powder of a polymer of vinyl pyrrolidone; forming a first solution comprising the powder and a polyol; and mixing the first solution with a second solution comprising a metal precursor capable of being reduced to a metal by the polyol.
FILED Wednesday, May 30, 2007
APPL NO 11/755720
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/362
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US 07824467 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Gabriella Metraux (Evanston, Illinois)
ABSTRACT A method of preparing metal nanoprisms having a unimodal size distribution and a predetermined thickness. The present method also allows control over nanoprism edge length.
FILED Wednesday, June 29, 2005
APPL NO 11/629830
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/371
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US 07824473 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Joseph T. Hupp (Northfield, Illinois);  Omar K. Farha (Evanston, Illinois);  Alexander M. Spokoyny (Evanston, Illinois);  Karen L. Mulfort (Chicago, Illinois)
ABSTRACT Disclosed herein are metal-organic frameworks of metals and boron rich ligands, such as carboranes and icosahedral boranes. Methods of synthesizing and using these materials in gas uptake are disclosed.
FILED Friday, July 25, 2008
APPL NO 12/180074
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Gas separation: Processes
095/116
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US 07824511 Baker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James J. Baker (Waldorf, Maryland);  Tina Woodland (Byran's Road, Maryland)
ABSTRACT A method for making high energy compositions, such as propellants, explosives, pyrotechnics or the like, including a solid metal particulate fuel dispersed in a cured binder matrix. The compositions are formed with ingredients including a particulate metal fuel such as boron, binder polymer (such as GAP polyol), binder plasticizer, and a curing agent containing isocyanate. The improved method includes pre-reacting the particulate metal fuel with an amount of isocyanate, which acts as a curative to neutralize residual acid. The particulate metal fuel/isocyanate from the pre-curing step is mixed together with the binder polymer, binder plasticizer, and remaining curing agent to form the solid propellant. The initial neutralization of the metal fuel avoids gassing and improves the mechanical properties of the propellant yield.
FILED Tuesday, July 03, 2007
APPL NO 11/879523
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Explosive and thermic compositions or charges
149/19.920
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US 07824539 Zhou et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Polytechnic Institute of New York University (Brooklyn, New York)
INVENTOR(S) Yanxiu Zhou (West Hartford, Connecticut);  Bin Yu (West Hardford, Connecticut);  Kalle Levon (Brooklyn, New York)
ABSTRACT Ionic interactions are monitored to detect hybridization. The measurement may be done measuring the potential change in the solution with the ion sensitive electrode (which may be the conducting polymer (e.g., polyaniline) itself), without applying any external energy during the binding. The double helix formation during the complimentary hybridization makes this electrode act as an ion selective electrode—the nucleotide hydrogen bonding is specific and thus monitoring the ionic phosphate group addition becomes selective. Polyaniline on the surface of nylon film forms a positively charged polymer film. Thiol linkage can be utilized for polyaniline modification and thiol-modified single strand oligonucleotide chains can be added to polyaniline. The sensitivity is because the double helix formation during the complimentary hybridization makes this electrode act as an ion selective electrode as the nucleotide hydrogen bonding is specific and thus monitoring the ionic phosphate group addition becomes selective.
FILED Friday, March 25, 2005
APPL NO 11/090944
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/792
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US 07824569 Newman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John K. Newman (Vicksburg, Mississippi);  David B. Ringelberg (Bradford, Vermont);  Kevin P. O'Connell (Abingdon, Maryland);  William A. Martin (Vicksburg, Mississippi);  Victor F. Medina (Vicksburg, Mississippi);  Steven L. Larson (Vicksburg, Mississippi)
ABSTRACT Modifications to the extracellular polymeric substance, predominantly extracellular polysaccharide, of a biopolymer produced by Rhizobium tropici ATCC 49672 yield a stable dry salt transported more easily than a fluid or gel and more stable than either. The salt may be re-constituted with water on-site. Embodiments may be employed as a soil amendment for soil strengthening, reducing hydraulic conductivity, erosion control and dust control as well as a metal chelator for contaminant remediation. Based on comparison with dextran standards, an embodiment demonstrated a molecular weight over 511,000 D. Embodiments include a day salt that is precipitated from solution and in use is re-hydrated back to original form. When added to a sandy soil at 0.1% by dry weight, an embodiment decreased the hydraulic conductivity by three orders of magnitude. These properties make embodiments of the present invention an attractive, “green” alternative to petroleum-based synthetic polymers for such applications as rapid roadway construction and soil erosion prevention.
FILED Wednesday, October 01, 2008
APPL NO 12/243084
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/88.100
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US 07824576 Pereira et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Nino R Pereira (Springfield, Virginia);  M Ashraf Imam (Great Falls, Virginia)
ABSTRACT A composite material includes lithium hydride particles dispersed within lithium to form a lithium-lithium hydride composite. The lithium-lithium hydride composite has increased strength over pure lithium and similar soft X-ray transmission characteristics as pure lithium. A soft X-ray blast window may be made from the lithium-lithium hydride composite with increased reliability and cost effectiveness. A method for making a composite material includes dispersing lithium hydride into lithium metal using a variety of dispersion techniques.
FILED Tuesday, March 23, 2010
APPL NO 12/729733
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/478
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US 07824582 Marks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Hu Kang (Evanston, Illinois)
ABSTRACT Unconventional twisted π-electron system electro-optic (EO) chromophores/compounds, compositions and related device structures. Crystallographic analysis of several non-limiting chromophores reveals, for instance, large ring-ring dihedral twist angles and a highly charge-separated zwitterionic structure in the ground state, in both solution phase and solid-state.
FILED Friday, March 24, 2006
APPL NO 11/389429
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/586
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US 07824645 Morgan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) Touchstone Research Laboratory, Ltd. (Triadelphia, West Virginia)
INVENTOR(S) Dwayne R. Morgan (Wheeling, West Virginia);  Rick D. Lucas (St. Clairsville, Ohio)
ABSTRACT A high density carbon material produced from coal is described. The carbon material may have a density ranging from about 1.0 g/cc to about 1.6 g/cc and may have a crush strength of up to about 20,000 psi. The high density carbon material is produced by slowly heating comminuted swelling bituminous coal particles under pressures of 400 psi to about 500 psi to a first temperature at about the initial plastic temperature of the coal. The material is held at this temperature for a period of time sufficient to provide for a uniform temperature throughout the coal. The material is then heated to a second temperature for a period of time sufficient to provide for the coal achieving an essentially uniform temperature. The resulting product is a three-dimensional, self-supporting carbon that has a substantially continuous carbon matrix defining grain boundaries within the carbon matrix. The characteristics of the carbon material may be altered by further heating to carbonize or graphitize the high density carbon material.
FILED Thursday, January 20, 2005
APPL NO 11/039775
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/445.R00
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US 07824775 Copley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Stephen M. Copley (State College, Pennsylvania);  William G. Rhoads (Bellefonte, Pennsylvania);  Chris A. Sills (State College, Pennsylvania);  Eduard S. Ventsel (State College, Pennsylvania)
ABSTRACT An autogenously welded structure is provided that includes a first face sheet, a plurality of individual stiffener elements, and a second face sheet. The stiffener elements each have a first edge disposed against the first face sheet and an opposed second edge. Each stiffener element has a central portion extending between the opposed edges. The central portion is disposed at an angle to the first face sheet. The stiffener elements include at least some stiffener elements that are disposed at an angle to at least some of the other stiffener elements. The second face sheet is disposed against the second edges of the stiffener elements and the first and second face sheets are autogenously welded to the edges of the stiffener elements.
FILED Monday, June 19, 2006
APPL NO 11/455446
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/593
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US 07824802 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Shengshui Zhang (Olney, Maryland);  Kang Xu (North Potomac, Maryland);  T. Richard Jow (Potomac, Maryland)
ABSTRACT A method of preparing a composite cathode active material having superior cell characteristics includes mixing and milling starting material, carbon and an organic complexing agent. The mixture is heated at a first temperature in an inert atmosphere to form a composite precursor, and then the precursor is ground and heated at a second temperature in an inert atmosphere to produce a carbon-containing composite cathode material having high electronic conductivity. The said composite cathode has a general formula of LiFe1−xMxPO4—C, within 0≦x<1, M is selected from the group consisting of Co, Ni, V, Cr, Mn and a mixture thereof.
FILED Wednesday, January 17, 2007
APPL NO 11/623777
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/218.100
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US 07824857 Mitas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Michael Mitas (Mt. Pleasant, South Carolina);  David J. Cole (Mt. Pleasant, South Carolina);  William E. Gillanders (Charleston, South Carolina);  Michael Wallace (Ponte Vedra Beach, Florida)
ABSTRACT Provided is a method for detecting metastases of epithelial cancers, comprising detecting in non-primary tissue overexpression of a nucleic acid of KS1/4, or detecting in non-primary tissue overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx, the overexpression of a nucleic acid of KS1/4, or the overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx in non-primary tissue being correlated with metastases of epithelial cancers.
FILED Thursday, December 02, 2004
APPL NO 11/003223
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 07824864 Alving et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Carl R Alving (Bethesda, Maryland);  Gary R Matyas (Olney, Maryland);  Nabila M Wassef (Potomac, Maryland);  Mangala Rao (Silver Spring, Maryland)
ABSTRACT The invention is a method and assay for detecting human squalene antibodies in sera or plasma using a blocking agent of −0.5% casein in a phosphate buffered saline (PBS) solution.
FILED Friday, January 07, 2005
APPL NO 11/030330
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
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US 07824875 Ching et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Wei-Mei Ching (Bethesda, Maryland);  Chien-Chung Chao (N. Bethesda, Maryland);  Xuan Li (Silver Spring, Maryland);  Hua-Wei Chen (Germantown, Maryland)
ABSTRACT The invention relates to a method for the detection of prior exposure to Coxiella burnetii infection by antibody-based assays using recombinant, immunodominant C. burnetii polypeptides. The invention also relates to the design of biotin or His-tagged C. burnetii proteins useful in the antibody-based assays as standardized antigen reagents.
FILED Tuesday, December 11, 2007
APPL NO 12/001599
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.320
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US 07824909 Ching et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Wei-Mei Ching (Bethesda, Maryland);  Chien-Chung Chao (N. Bethesda, Maryland);  Xuan Li (Silver Spring, Maryland);  Hua-Wei Chen (Germantown, Maryland)
ABSTRACT The invention relates to a method for the detection of prior exposure to Coxiella. burnetii infection by antibody-based assays using recombinant, immunodominant C. burnetii polypeptides. The invention also relates to the design of biotin or His-tagged C. burnetii proteins useful in the antibody-based assays as standardized antigen reagents.
FILED Tuesday, December 11, 2007
APPL NO 12/001598
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
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US 07825037 Brueck et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Steven R. J. Brueck (Albuquerque, New Mexico);  Deying Xia (Albuquerque, New Mexico)
ABSTRACT In accordance with the invention, there is a method of forming a nanochannel including depositing a photosensitive film stack over a substrate and forming a pattern on the film stack using interferometric lithography. The method can further include depositing a plurality of silica nanoparticles to form a structure over the pattern and removing the pattern while retaining the structure formed by the plurality of silica nanoparticles, wherein the structure comprises an enclosed nanochannel.
FILED Monday, October 16, 2006
APPL NO 11/549732
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/778
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825045 Wagner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) University of Delaware (Newark, Delaware)
INVENTOR(S) Norman J. Wagner (Newark, Delaware);  Eric D. Wetzel (Baltimore, Maryland)
ABSTRACT An armor composite material has been invented which contains a fabric which has been impregnated with shear thickening fluid. This invention offers a ballistic resistant material that is more flexible and less bulky than comparable, conventional ballistic fabric. The material in the alternative can be puncture resistant. The invented material offers superior ballistic performance and/or puncture resistance compared to conventional ballistic fabric-based materials of equal thickness. The invented material can be applied to applications requiring armor that is compact and/or flexible, such as body armor, protective clothing and flexible protective devices and shields, and stab resistant clothing and devices.
FILED Friday, February 13, 2009
APPL NO 12/370669
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Fabric
442/59
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825154 Bavari et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Sina Bavari (Frederick, Maryland);  Rick Gussio (Frederick, Maryland);  James C. Burnett (Richmond, Virginia)
ABSTRACT Disclosed herein are methods of inhibiting the activity of Botulinum neurotoxin A metalloprotease with the compounds disclosed herein. Also disclosed are methods of treating, inhibiting or preventing intoxication caused by bacteria of at least one bacterial strain in a subject, and pharmaceutical and cosmetic compositions comprising the compounds disclosed herein.
FILED Friday, August 11, 2006
APPL NO 11/464007
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/411
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825248 Shenoy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Devanand K Shenoy (McLean, Virginia);  Enrico Dalcanale (Parma, Italy);  Sander Willems (Parma, Italy);  Marco Busi (Parma, Italy)
ABSTRACT A compound and methods of making thereof having the structure shown below is disclosed. Each Ar is an aromatic group. Each M is palladium, platinum, or rhenium. At least one X in the compound has an aliphatic having at least 1 carbon atom. Each x, each y, and each z is an integer greater than or equal to zero. Each m is an integer greater than or equal to one. n is an integer greater than or equal to three.
FILED Friday, January 23, 2009
APPL NO 12/358497
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/2
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US 07825405 Kim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Sungjee Kim (Pasadena, California);  Moungi G. Bawendi (Cambridge, Massachusetts)
ABSTRACT A semiconductor nanocrystal heterostructure has a core of a first semiconductor material surrounded by an overcoating of a second semiconductor material. Upon excitation, one carrier can be substantially confined to the core and the other carrier can be substantially confined to the overcoating.
FILED Thursday, June 12, 2008
APPL NO 12/213001
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Active solid-state devices
257/40
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US 07825440 Choudhury
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Debabani Choudhury (Thousand Oaks, California)
ABSTRACT A suspended-membrane/suspended-substrate monolithic microwave integrated circuit module and method of making same. The device contains a plurality of active devices, such as transistors, a plurality of transmission mediums connected to the active devices; and a substrate having a first portion supporting the active devices and the transmission mediums thereon, and further having a plurality of discrete second portions extending from the first portion. The method teaches how to manufacture the device.
FILED Thursday, December 29, 2005
APPL NO 11/324066
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/275
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825736 McGuyer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
National Defense Science and Engineering Graduate Fellowship (NDSEG)
APPLICANT(S)
ASSIGNEE(S) Princeton University (Princeton, New Jersey)
INVENTOR(S) Bart H. McGuyer (Princeton, New Jersey);  Yuan-Yu Jau (Princeton, New Jersey);  William Happer (Princeton, New Jersey)
ABSTRACT The present invention relates to a method and system to suppress or eliminate light shift in an optical pumping system, such as an atomic clock. The method uses modulation of a radiation source, such as a radio frequency or microwave source, to simultaneously lock the frequency of the radiation source to an atomic resonance and lock the frequency of the optical pumping source in order to suppress or eliminate light shift. In one embodiment, the method of the present invention directly utilizes the out-of-phase channel of a lock-in amplifier to additionally lock an optical pumping source to a zero-light-shift frequency, where the in-phase channel is used to lock the frequency of the radiation source to an atomic resonance.
FILED Thursday, December 18, 2008
APPL NO 12/338044
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Oscillators
331/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825741 Reynolds et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Scott Kevin Reynolds (Amawalk, New York);  Mehmet Soyuer (Stamford, Connecticut);  Chinmaya Mishra (San Diego, California)
ABSTRACT A method of generating an output signal from an input signal includes a step of generating a set of n signals, n being an integer greater than or equal to 3, by generating a signal for each integer i such that 0≦i≦(n−1), each signal within the set having the same frequency and approximately equal amplitude and a phase equal to (360/n)i degrees. The method also includes a step of inputting each of the set of n signals to a gate terminal of a corresponding one of a set of n transistors. Each of the transistors has a source terminal electrically connected to a common voltage drain and each of the transistors has a drain terminal electrically connected to a coupling. The coupling is electrically connected to a common voltage source. The output signal at the coupling has a frequency equal to the frequency of the input signal multiplied by n.
FILED Tuesday, May 27, 2008
APPL NO 12/127389
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Oscillators
331/57
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US 07825743 Tsuzuki et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Defense Sciences Office (DSO)
APPLICANT(S)
ASSIGNEE(S) Superconductor Technologies, Inc. (Santa Barbara, California)
INVENTOR(S) Genichi Tsuzuki (Ventura, California);  Matthew P. Hernandez (Santa Barbara, California);  Balam A. Willemsen (Newbury Park, California)
ABSTRACT Methods, systems and apparatus for filter design, analysis and adjustment are provided. Various embodiments may include, for example, methods, systems and apparatus for electric signal filter tuning. Embodiments may also include design techniques for planar electric signal (e.g., RF signals) filter tuning. In at least an embodiment of the present invention a technique for filter tuning is provided which may include parameter extraction, optimization and tuning recipes techniques that may require only a single permanent filter tuning. In at least another embodiment a system and method of filter design, analysis and adjustment according to the present invention includes use of tuning that may be set using a mechanical scribing tool or a laser trimming device. In at least one other embodiment, a filter tuning technique may be provided and include providing trimming tabs on a resonator edge that may be disconnected or trimmed for filter tuning.
FILED Monday, December 08, 2008
APPL NO 12/330510
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Wave transmission lines and networks
333/17.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826060 Saraf et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Ravi Saraf (Lincoln, Nebraska);  Gaurav Singh (Lincoln, Nebraska)
ABSTRACT The present invention directly measures localized electrochemical processes on a planar electrode using differential interferometry. The ionic charge accumulation at the electrode-electrolyte interface may be directly measured by using differential interferometry as a function of magnitude and frequency (for example, 2-50 kHz) of an external potential applied on an electrode. Methods in accordance with the present invention probe the ion dynamics confined to the electrical double layer. An electric field is applied using a pure AC potential and a superposition of AC and DC-ramp potential to measure ion concentration and detect redox processes.
FILED Monday, June 02, 2008
APPL NO 12/131647
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
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US 07826145 Justis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Nicole B. Justis (Cardiff-by-the-Sea, California);  De-Ying Zhang (San Diego, California);  Yu-Hwa Lo (San Diego, California)
ABSTRACT The present invention in various embodiments relates to a variety of different types of fluidic adaptive lens systems, pumping systems for implementation in such lens systems, other systems employing such lens systems, and related methods of fabrication. In at least some embodiments, the present invention relates to a lens system that includes a reservoir having at least one flexible wall, a first actuator coupled in relation to the reservoir, and a terminal at which is located at least one of an integrated fluidic lens and a port configured to be coupled to an external fluidic lens. The terminal is coupled to at least one of the reservoir and the actuator, and at least one of the actuator and a first pumping system including the actuator is capable of causing fluid to be moved at least one of from the reservoir toward the terminal, and from the terminal toward the reservoir.
FILED Friday, November 04, 2005
APPL NO 11/577905
ART UNIT 2873 — Optics
CURRENT CPC
Optical: Systems and elements
359/666
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826250 Kuhr et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) North Carolina State Univeristy (Raleigh, North Carolina)
INVENTOR(S) Werner G. Kuhr (Oak Hills, California);  David F. Bocian (Riverside, California);  Jonathan S. Lindsey (Raleigh, North Carolina);  Kristian A. Roth (Riverside, California)
ABSTRACT This invention provides approaches to improve the signal to noise ratio (S/N) in electrochemical measurements (e.g., amperometry, voltammetry, etc.). In particular, a method is described wherein the faradaic current is temporally dissociated from the charging current associated with reading the charge of a redox-active species (e.g., a self-assembled monolayer (SAM)). This method, designated herein as open circuit potential amperometry (OCPA), quantitatively reads the charge of the redox species bound to (electrically coupled to) an electrode surface, while discriminating against both charging current(s) and amperometric signal(s) that arise, e.g., from diffusion-based species in solution.
FILED Thursday, April 07, 2005
APPL NO 11/102089
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/151
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826509 Belkin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Mikhail A. Belkin (Somerville, Massachusetts);  Benjamin G. Lee (Cambridge, Massachusetts);  Ross M. Audet (Palo Alto, California);  James B. MacArthur (Somerville, Massachusetts);  Laurent Diehl (Cambridge, Massachusetts);  Christian Pflügl (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts)
ABSTRACT A broadly tunable single-mode infrared laser source based on semiconductor lasers. The laser source has two parts: an array of closely-spaced DFB QCLs (or other semiconductor lasers) and a controller that can switch each of the individual lasers in the array on and off, set current for each of the lasers and, and control the temperature of the lasers in the array. The device can be used in portable broadband sensors to simultaneously detect a large number of compounds including chemical and biological agents. A microelectronic controller is combined with an array of individually-addressed DFB QCLs with slightly different DFB grating periods fabricated on the same broadband (or multiple wavelengths) QCL material. This allows building a compact source providing narrow-line broadly-tunable coherent radiation in the Infrared or Terahertz spectral range (as well as in the Ultraviolet and Visible spectral ranges, using semiconductor lasers with different active region design). The performance (tuning range, line width, power level) is comparable to that of external grating tunable semiconductor lasers, but the proposed design is much smaller and much easier to manufacture.
FILED Friday, December 15, 2006
APPL NO 11/611819
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/50.122
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826592 Jaffray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) William Beaumont Hospital (Royal Oak, Michigan)
INVENTOR(S) David A. Jaffray (Windsor, Canada);  John W. Wong (Bloomfield Hills, Michigan);  Jeffrey H. Siewerdesen (Ann Arbor, Michigan)
ABSTRACT A radiation therapy system that includes a radiation source that moves about a path and directs a beam of radiation towards an object and a cone-beam computer tomography system. The cone-beam computer tomography system includes an x-ray source that emits an x-ray beam in a cone-beam form towards an object to be imaged and an amorphous silicon flat-panel imager receiving x-rays after they pass through the object, the imager providing an image of the object. A computer is connected to the radiation source and the cone beam computerized tomography system, wherein the computer receives the image of the object and based on the image sends a signal to the radiation source that controls the path of the radiation source.
FILED Friday, November 21, 2008
APPL NO 12/313646
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/65
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826693 Agashe et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Shashank S. Agashe (Mountain View, California);  Kuen-Ting R. Shiu (Ann Arbor, Michigan);  Stephen R. Forrest (Ann Arbor, Michigan)
ABSTRACT A reconfigurable optical add-drop multiplexer comprises a first waveguide layer having formed therein a first multiplexer-demultiplexer, a second multiplexer-demultiplexer, and a plurality of optical switches. The reconfigurable optical add-drop multiplexer further comprises a second waveguide layer optically coupled to the first waveguide and having a second effective index of refraction, said second waveguide layer having an optical amplifier formed therein. An input signal is amplified by the optical amplifier and communicated to the first optical multiplexer-demultiplexer where the signal is demultiplexed into a plurality individual wavelength signals. The second optical multiplexer-demultiplexer is adapted to receive a multiplexed add signal and to demultiplex the add signal into component wavelength signals. The individual wavelength signals are received at the optical switches and selectively routed to either an optical detector or toward the first multiplexer-demultiplexer. The individual wavelength signals received at the first multiplexer-demultiplexer are multiplexed into an output signal.
FILED Friday, October 26, 2007
APPL NO 11/925521
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826878 Alfano et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Research Foundation of City University of New York (New York, New York)
INVENTOR(S) Robert R. Alfano (Bronx, New York);  Min Xu (Woodside, New York);  Mohammed Alrubaiee (New York, New York);  Swapan Kumar Gayen (Marlboro, New Jersey)
ABSTRACT Disclosed is a system and a method for detecting the presence of one or more objects in a turbid medium, the method including: illuminating at least a portion of the turbid medium with incident light having at least one wavelength which interacts with the one or more objects contained in the turbid medium differently than the incident light interacts with the turbid medium; measuring light that emerges from the turbid medium; and detecting and locating the one or more objects using Independent Component Analysis (ICA) of the emergent light from the turbid medium. The present invention is useful for medical applications, such as for finding and locating, a tumor(s) in body organs, or excised tissues. Moreover, the present invention can be used to locate objects in obscuring medium, such as, mines in shallow coastal water, a plane in fog, military targets under fog, smoke or cloud cover.
FILED Wednesday, December 07, 2005
APPL NO 11/296831
ART UNIT 3737 — Optics
CURRENT CPC
Surgery
6/310
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826894 Musallam et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Sam Musallam (Pasadena, California);  Richard A. Andersen (La Canada, California);  Brian D. Corneil (London, Canada);  Bradley Greger (Van Nuys, California);  Hansjorg Scherberger (Zurich, Switzerland)
ABSTRACT In an embodiment, the invention relates to neural prosthetic devices in which control signals are based on the cognitive activity of the prosthetic user. The control signals may be used to control an array of external devices, such as prosthetics, computer systems, and speech synthesizers. Data obtained from monkeys' movement intentions were recorded, decoded with a computer algorithm, and used to position cursors on a computer screen. Not only the intended goals, but also the value of the reward the animals expected to receive at the end of each trial, were decoded from the recordings. The results indicate that brain activity related to cognitive variables can be a viable source of signals for the control of a cognitive-based neural prosthetic.
FILED Tuesday, March 22, 2005
APPL NO 11/086534
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/544
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827011 DeVaul et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Aware, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Richard W. DeVaul (Somerville, Massachusetts);  Daniel Barkalow (Somerville, Massachusetts);  Christopher Elledge (Arlington, Massachusetts)
ABSTRACT A method to achieve an accurate, extremely low power state classification implementation is disclosed. Embodiments include a sequence that matches the data flow from the sensor transducer, through analog filtering, to digital sampling, feature computation, and classification.
FILED Wednesday, November 21, 2007
APPL NO 11/986528
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/190
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827124 McKinstry et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Neurosciences Research Foundation, Inc. (San Diego, California)
INVENTOR(S) Jeffrey L. McKinstry (San Diego, California);  Gerald M. Edelman (La Jolla, California);  Jeffrey L. Krichmar (Cardiff-by-the-Sea, California)
ABSTRACT A mobile brain-based device (BBD) includes a mobile platform with sensors and effectors, which is guided by a simulated nervous system that is an analogue of the cerebellar areas of the brain used for predictive motor control to determine interaction with a real-world environment. The simulated nervous system has neural areas including precerebellum nuclei (PN), Purkinje cells (PC), deep cerebellar nuclei (DCN) and an inferior olive (IO) for predicting turn and velocity control of the BBD during movement in a real-world environment. The BBD undergoes training and testing, and the simulated nervous system learns and performs control functions, based on a delayed eligibility trace learning rule.
FILED Wednesday, December 27, 2006
APPL NO 11/646930
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827381 Manczak et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Oracle America, Inc. (Redwood City, California)
INVENTOR(S) Olaf Manczak (Hayward, California);  Christopher A. Vick (San Jose, California);  Michael H. Paleczny (San Jose, California);  Jay R. Freeman (Palo Alto, California);  Phyllis E. Gustafson (Pleasanton, California)
ABSTRACT A computer system may employ a first memory virtualization and corresponding virtual-to-physical address translation technique for a first application executing on a processor and a second memory virtualization and corresponding virtual-to-physical address translation technique for a second application executing on the same processor transparent to the first application. Different virtualization and corresponding translation techniques may be employed on a per-thread basis, rather than a per-application basis. Different virtualization and corresponding translation techniques may be employed for accesses to different ranges of virtual or corresponding physical addresses. Different virtualization and corresponding translation techniques may employ different page sizes. A first or second virtualization and corresponding translation technique may include page-based, segment-based, or function-based virtual-to-physical address translation. The selection of a first or second memory virtualization and corresponding address translation technique may be dependent on a predicted workload and/or on a user policy.
FILED Monday, June 05, 2006
APPL NO 11/446644
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/203
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827428 Arimilli et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lakshminarayana B. Arimilli (Austin, Texas);  Ravi K. Arimilli (Austin, Texas);  Bernard C. Drerup (Austin, Texas);  Jody B. Joyner (Austin, Texas);  Jerry D. Lewis (Round Rock, Texas)
ABSTRACT A system for providing a cluster-wide system clock in a multi-tiered full graph (MTFG) interconnect architecture are provided. Heartbeat signals transmitted by each of the processor chips in the computing cluster are synchronized. Internal system clock signals are generated in each of the processor chips based on the synchronized heartbeat signals. As a result, the internal system clock signals of each of the processor chips are synchronized since the heartbeat signals, that are the basis for the internal system clock signals, are synchronized. Mechanisms are provided for performing such synchronization using direct couplings of processor chips within the same processor book, different processor books in the same supernode, and different processor books in different supernodes of the MTFG interconnect architecture.
FILED Friday, August 31, 2007
APPL NO 11/848440
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Support
713/375
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07823460 White
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)
ASSIGNEE(S) Advanced Mechanical Technology, Inc. (Watertown, Massachusetts)
INVENTOR(S) Bruce F. White (Natick, Massachusetts)
ABSTRACT A virtual soft tissue control system that provides enhanced motion control to a prosthetic simulator machine. The control system advantageously adds a “virtual soft tissue” control scheme to a conventional control system, such as a digital proportional integral derivative (PID) controller, to algorithmically model the soft tissue constraints that would be encountered by the prosthesis within the human body, and account for these forces in driving the simulator. In another aspect, a prosthetic simulator comprises a prosthetic drive mechanism; a feedback control system that drives the prosthetic drive mechanism; and an iterative learning control system that determines an error from a previous iteration of motion of the drive mechanism and uses the error to determine a drive signal for a subsequent iteration of motion. In certain embodiments, the prosthetic simulator uses both a soft tissue model and an iterative learning control system.
FILED Monday, August 14, 2006
APPL NO 11/503867
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/804
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824335 Wodnicki
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Robert Gideon Wodnicki (Niskayuna, New York)
ABSTRACT An imaging probe having multi-level transmitter cells. The imaging probe includes a plurality of acoustical sub-elements for transmitting and receiving acoustic energy for imaging. Each of the multi-level transmitter cells is arranged along a respective transmitter cell path between a switching matrix and one of the acoustical sub-elements. The multi-level transmitter cells in the probe are capable of producing signals having multiple voltage levels.
FILED Thursday, April 26, 2007
APPL NO 11/796002
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Surgery
6/437
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824424 Jensen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Joel F. Jensen (Redwood City, California);  Philip S. Green (Palo Alto, California)
ABSTRACT The invention is directed to a system and method for releasably holding a surgical instrument (14), such as an endoscopic instrument configured for delivery through a small percutaneous penetration in a patient. The instrument comprises an elongate shaft (100) with a pair of mounting pins (116) laterally extending from the shaft between its proximal and distal ends. An instrument holder comprises a support having a central bore (202) and an axially extending slot (204) for receiving the instrument shaft and the mounting pins. A pair of locking slots (206) are cut into the support transversely to and in communication with the axial slot so that the mounting pins can be rotated within the locking slots. The instrument support further includes a latch assembly for automatically locking the mounting pins within the locking slots to releasably couple the instrument to the instrument holder. With this twist-lock motion, the surgeon can rapidly engage and disengage various instruments from the holder during a surgical procedure, such as open surgery, laparoscopy or thoracoscopy.
FILED Monday, August 01, 2005
APPL NO 11/195494
ART UNIT 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
66/205
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824653 Shih et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Wei-Heng Shih (Bryn Mawr, Pennsylvania);  Wan Y. Shih (Bryn Mawr, Pennsylvania);  Hui Li (Philadelphia, Pennsylvania);  Melissa Colleen Schillo (Broadview Heights, Ohio)
ABSTRACT An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm to 700 nm. Highly luminescent metal sulfide (MS) QDs are produced via an aqueous synthesis route. MS QDs are capped with thiol-containing charged molecules in a single step. The resultant MS QDs exhibit the distinctive excitonic photoluminescence desired of QDs and can be fabricated to avoid undesirable broadband emissions at higher wavelengths. This provides a significant improvement over the present complex and expensive commercial processes for the production of QDs. The aqueous QDs are stable in biological fluids over a long period of time. In addition, nontoxic ZnS QDs have been produced with good photoluminescence properties by refluxing the ZnS QD suspensions over a period of time.
FILED Wednesday, September 02, 2009
APPL NO 12/552970
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/561.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824660 Buzatu et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Dan A. Buzatu (Benton, Arkansas);  Jon G. Wilkes (Little Rock, Arkansas);  Dwight Miller (White Hall, Arkansas);  Jerry A. Darsey (Little Rock, Arkansas);  Tom Heinze (White Hall, Arkansas);  Alex Birls (Little Rock, Arkansas);  Richard Beger (White Hall, Arkansas)
ABSTRACT The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubes and other similar nanostructures as both an indirect source of radiation therapy (BNCT), and as delivery vehicles for other types of radio- and chemo-therapeutic materials, as well as imaging agents for diagnostic purposes.
FILED Wednesday, April 30, 2008
APPL NO 12/112986
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.490
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824672 Chaikof et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Elliot L. Chaikof (Dunwoody, Georgia);  Wanxing Cui (Norcross, Georgia);  Zhifei Dai (Harbin, China PRC)
ABSTRACT The invention comprises anti-inflammatory conformal barriers with controllable permeability properties that can be applied to living cells prior to transplant, and methods for coating living cells with conformal barriers. The coatings comprise polymer layers deposited on a cell surface by layer-by-layer polymer assembly, wherein each layer contains a positive and a negative polymer pair. The barriers can be actively anti-inflammatory through incorporation of anticoagulant and/or anti-inflammatory agents into the barrier.
FILED Monday, March 28, 2005
APPL NO 11/091939
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824680 Varner
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Judith A. Varner (Encinitas, California)
ABSTRACT The invention provides methods for detecting and inhibiting angiogenesis, endothelial cell adhesion, and endothelial cell migration using agents which inhibit the specific binding of integrin α4β1 to one or more of its ligands. The invention further provides methods for screening test compounds for their ability to inhibit angiogenesis, endothelial cell adhesion, or endothelial cell migration by employing agents which inhibit the specific binding of integrin α4β1 to one or more of its ligands. The invention additionally relates to methods for isolating endothelial progenitor cells which express integrin α4β1. The methods of the invention are useful in, for example, diagnosing and inhibiting pathological conditions that are associated with angiogenesis, endothelial cell adhesion, and/or endothelial cell migration. The invention's methods are also useful in isolating endothelial progenitor cells, and in determining the mechanisms that underlie angiogenesis, development, wound healing, and the function of the female reproductive system.
FILED Thursday, August 01, 2002
APPL NO 10/485758
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/143.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824681 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dimiter S. Dimitrov (Frederick, Maryland);  Yang Feng (Frederick, Maryland)
ABSTRACT Disclosed herein are isolated monoclonal human antibodies that specifically binds insulin-like growth factor II (IGF-II) with an equilibrium dissociation constant (Kd) of 1 nM or less, wherein the antibody bind IGF-I with an equilibrium dissociation constant (Kd) of 1 mM or greater. The antibodies inhibit phosphorylation of the insulin-like growth factor receptor. Nucleic acids encoding these antibodies, expression vectors including these nucleic acids, and isolated host cells that express the nucleic acids are also disclosed. The antibodies can be used to detect human IGF-II in a sample. Methods of diagnosing a tumor are disclosed herein that utilize these antibodies. Methods of treating a subject with a tumor are also disclosed.
FILED Tuesday, August 15, 2006
APPL NO 12/063749
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/145.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824682 Epstein et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Neal D. Epstein (Chevy Chase, Maryland);  Shahin Hassanzadeh (Fairfax, Virginia);  Steve O. Winitsky (Alexandria, Virginia);  Julien S. Davis (Baltimore, Maryland)
ABSTRACT The present disclosure provides a cDNA, protein sequence, and genomic structure of the human cardiac isoform of myosin light chain kinase (cMLCK), and describes mutations in the cMLCK gene that are associated with cardiac dysfunction. Methods are provided for identifying individuals who can harbor mutations in the cMLCK gene, or carry alleles that can predisposed them to cardiac dysfunction. Disclosed also is a significant role for cMLCK in modulating cardiac contractility. The cMLCK protein is shown herein to reduce the amplitude of stretch activation and increase the tension production, a property of muscle which has heretofore had an unknown role in cardiac contraction. Moreover, the cMLCK protein is shown to be regionally distributed in the heart, thereby having differential effects on contractility and stretch activation. Methods herein are provided to exploit this effect of cMLCK, to treat individuals who have or are prone to cardiac dysfunction. In addition, methods are provided to identify agents that modulate cMLCK activity, thereby having potential therapeutic importance in the treatment of cardiac dysfunction.
FILED Friday, April 11, 2008
APPL NO 12/101812
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/146.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824685 Thompson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Baylor College of Medicine (Houston, Texas)
INVENTOR(S) Timothy C. Thompson (Houston, Texas);  Chengzhen Ren (Pearland, Texas)
ABSTRACT This invention relates to a gene encoding RTVP that has been shown to be up-regulated by p53 using differential display-PCR and subsequently by co-transfection studies. RTVP-1 mRNA is abundant in normal mouse and human prostatic epithelial cells and primary tumors, but is significantly down regulated in metastatic mouse and human prostate cancer. In prostate cancer cells overexpression of the mouse RTVP-1 gene (mRTVP-1) induced apoptosis that was accompanied by increased caspase 8, 9 and 3 activities. mRTVP-1-stimulated apoptosis was also associated with increased levels of bax, bad and activated BID; reduced levels of bcl-2 and bcl-XL; and cytosolic cytochrome c accumulation. Adenoviral-vector-mediated mRTVP-1 expression lead to potent growth suppression and antimetastatic activities in an orthotopic mouse model of prostate cancer in vivo. These therapeutic activities were associated with anti-angiogenic effects and importantly a local and systemic immune response. Accordingly, p53 was linked with suppression of metastasis through its induction of mRTVP-1, which can concurrently induce apoptosis, suppress angiogenesis and stimulate an antitumor immune response. Thus, the invention includes compositions and methods, based on RTVP nucleic acid, polypeptides, and antibodies, for use in the treatment, prevention and detection of neoplastic disease and, specifically, metastatic prostatic neoplasia.
FILED Wednesday, January 19, 2005
APPL NO 11/038285
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824687 Danishefsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Sloan-Kettering Institute For Cancer Research (New York, New York)
INVENTOR(S) Samuel J. Danishefsky (Englewood, New Jersey);  Stacy J. Keding (New York, New York)
ABSTRACT The present invention provides novel clustered multi-antigenic constructs having the structure: and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive constructs as disclosed herein, either in conjugated form or unconjugated and in combination with a suitable immunogenic carrier.
FILED Wednesday, December 03, 2003
APPL NO 10/728041
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/193.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824692 Walker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Research Development Foundation (Carson City, Nevada)
INVENTOR(S) David H. Walker (Galveston, Texas);  Jere W. McBride (League City, Texas)
ABSTRACT Novel genes encoding homologous immunoreactive thio-disulfide oxidoreductases, or disulfide bond formation (Dsb) proteins from Ehrlichia chaffeensis and Ehrlichia canis are disclosed. While the E. chaffeensis and E. canis Dsb proteins are at most only 31% or less homologous to other known Dsb proteins, the Ehrlichia Dsbs contain a cysteine active site, Cys-Gly-Tyr-Cys, similar to those in known Dsb proteins. As predicted by 15-amino acid identical N-terminal signal peptides, the proteins are primarily localized in the periplasm of E. chaffeensis and E. canis, possibly playing a role in antigenicity and pathogenesis. The present invention provides the nucleotide and amino acid sequences and expression vectors for the E. chaffeensis and E. canis dsb genes, antisera directed against the proteins, and kits to determine whether an individual or animal is infected with a given species of Ehrlichia.
FILED Tuesday, September 30, 2008
APPL NO 12/242865
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/234.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824695 FitzGerald et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  Genentech, Inc. (South San Francisco, California)
INVENTOR(S) David J. FitzGerald (Rockville, Maryland);  Randall J. Mrsny (Los Altos Hills, California);  Marian McKee (Great Falls, Virginia);  Ann Daugherty (Los Altos Hills, California)
ABSTRACT This invention provides bioactive conjugates. The bioactive conjugates include: (1) a cell recognition moiety that binds to α2 macroglobulin receptor α2-MR and (2) a bioactive moiety which: (a) has a biological activity, (b) does not function solely as an immunogen to invoke an immune response and (c) does not have ADP ribosylating activity. The bioactive conjugates of this invention are useful in methods of transporting the bioactive moiety across a polar epithelial membrane. Thus, this invention provides methods for parenteral administration of proteins without injection.
FILED Wednesday, October 18, 2000
APPL NO 10/110880
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/260.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824709 Ryan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Children's Hospital and Research Center at Oakland (Oakland, California)
INVENTOR(S) Robert O. Ryan (El Cerrito, California);  Michael N. Oda (Fairfield, California)
ABSTRACT The invention provides compositions and methods for delivery of a bioactive agent to an individual. Delivery vehicles are provided that include a bioactive agent in disc shaped particles that include one or more lipid binding polypeptides circumscribing the perimeter of a lipid bilayer in which the bioactive agent is localized. Chimeric lipid binding polypeptides are also provided and may be used to add additional functional properties to the delivery particles.
FILED Friday, February 13, 2004
APPL NO 10/778640
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/489
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824847 Steinhardt
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of California (Oakland, California)
INVENTOR(S) Richard A. Steinhardt (Berkeley, California)
ABSTRACT Tissue preservation media comprising a polyoxyethylene/polyoxypropylene copolymer are used to preserve tissues and organs for storage and transplantation. In particular embodiments, the polyoxyethylene/polyoxypropylene copolymer is Pluronic F68 or FLOCOR (CRL-5861; purified poloxamer 188), and the medium is Steinhardt medium, polyoxyethylene/polyoxypropylene copolymer-supplemented Optisol GS or polyoxyethylene/polyoxypropylene copolymer-supplemented ViaSpan.
FILED Thursday, January 17, 2008
APPL NO 12/015793
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824857 Mitas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Michael Mitas (Mt. Pleasant, South Carolina);  David J. Cole (Mt. Pleasant, South Carolina);  William E. Gillanders (Charleston, South Carolina);  Michael Wallace (Ponte Vedra Beach, Florida)
ABSTRACT Provided is a method for detecting metastases of epithelial cancers, comprising detecting in non-primary tissue overexpression of a nucleic acid of KS1/4, or detecting in non-primary tissue overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx, the overexpression of a nucleic acid of KS1/4, or the overexpression of a combination of nucleic acids of KS1/4 and PIP, of nucleic acids of KS1/4 and mam, of nucleic acids of PIP and mam, of nucleic acids of KS1/4, PIP and mam, or of nucleic acids of KS1/4 and lunx in non-primary tissue being correlated with metastases of epithelial cancers.
FILED Thursday, December 02, 2004
APPL NO 11/003223
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824862 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Third Wave Technologies, Inc. (Madison, Wisconsin)
INVENTOR(S) Fang Dong (Boulder, Colorado);  Victor I. Lyamichev (Madison, Wisconsin);  James R. Prudent (Madison, Wisconsin);  Lance Fors (Monrovia, California);  Bruce P. Neri (Carlsbad, California);  Mary Ann D. Brow (Madison, Wisconsin);  Todd A. Anderson (Madison, Wisconsin);  James E. Dahlberg (Madison, Wisconsin)
ABSTRACT The present invention relates to methods and compositions for analyzing nucleic acids. In particular, the present invention provides methods and compositions for the detection and characterization of nucleic acid sequences and sequence changes. The methods of the present invention permit the detection and/or identification of genetic polymorphism such as those associated with human disease and permit the identification of pathogens (e.g., viral and bacterial strain identification).
FILED Tuesday, September 30, 2008
APPL NO 12/242508
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824868 Höök et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Magnus Höök (Houston, Texas);  Sabitha Prabhakaran (Pearland, Texas)
ABSTRACT Provided herein is a method for inducing formation of a conformationally distinct superfibronectin by contacting plasma fibronectin with BBK32 protein or a BBK32 peptide and the BBK32-induced superfibronectin so formed. Also provided are methods of inhibiting endothelial cell proliferation, of treating pathophysiological conditions associated with endothelial cell proliferation and of inhibiting angiogenesis therein using the BBK32 protein, BBK32 peptide or the BBK32-induced superfibronectin.
FILED Friday, April 18, 2008
APPL NO 12/148389
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824874 Dertinger
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Litron Laboratories, Ltd. (Rochester, New York)
INVENTOR(S) Stephen D. Dertinger (Webster, New York)
ABSTRACT The present invention relates a method for the enumeration of in vivo gene mutation. The method utilizes differential staining of GPI-anchor deficient erythrocyte populations to distinguish between wild-type and pig-a gene mutants. Quantitative analyses can be conducted on erythrocytes and/or reticulocytes, and is based upon fluorescent emission and light scatter following exposure to an excitatory light source. Counting of mutant erythrocytes or reticulcoytes relative to the number of total erythrocytes or reticulocytes can be used to assess the DNA-damaging potential of an exogenous chemical agent, the DNA-damaging potential of an exogenous physical agent, the effects of an exogenous agent which can modify endogenously-induced DNA damage, and the effects of an exogenous agent which can modify exogenously-induced DNA damage. Kits for practicing the invention are also disclosed.
FILED Wednesday, May 23, 2007
APPL NO 11/752726
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.250
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824889 Vogelstein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Bert Vogelstein (Baltimore, Maryland);  Kenneth W. Kinzler (BelAir, Maryland)
ABSTRACT The identification of pre-defined mutations expected to be present in a minor fraction of a cell population is important for a variety of basic research and clinical applications. The exponential, analog nature of the polymerase chain reaction is transformed into a linear, digital signal suitable for this purpose. Single molecules can be isolated by dilution and individually amplified; each product is then separately analyzed for the presence of pre-defined mutations. The process provides a reliable and quantitative measure of the proportion of variant sequences within a DNA sample.
FILED Friday, February 23, 2007
APPL NO 11/709742
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824893 Deiters et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Alexander Deiters (Raleigh, North Carolina);  Peter G. Schultz (La Jolla, California)
ABSTRACT The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate alkynyl amino acids such as para-propargyloxyphenylalanine into proteins produced in a eubacteria host such as E. coli. The invention provides novel orthoghonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing alkynyl amino acids, and cellular translation systems.
FILED Tuesday, September 20, 2005
APPL NO 11/663513
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/183
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824912 Sherley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) James L. Sherley (Boston, Massachusetts);  Krisha Panchalingam (Medford, Massachusetts)
ABSTRACT The present invention is directed to methods for readily propagating somatic liver stem cells. The methods comprise enhancing guanine nucleotide (GNP) biosynthesis, thereby expanding guanine nucleotide pools. This in turn conditionally suppresses asymmetric cell kinetics in the explanted cells. The methods of the invention include pharmacological methods and genetic methods. For example, the resulting cultured somatic liver stem cells can be used for a variety of applications including cell replacement therapies, gene therapies, drug discovery applications, and tissue engineering applications, such as the generation of artificial liver.
FILED Wednesday, June 21, 2006
APPL NO 11/472238
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825086 Mitra
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Ashim K. Mitra (Overland Park, Kansas)
ABSTRACT Dipeptide and tripeptide ester derivatives of acyclovir and its analogs are disclosed which are useful to treat herpes virus infections. Also disclosed is a method for preparing a therapeutic agent for targeted delivery to ocular tissue comprising linking the therapeutic agent to one or more groups of the formula —X—Y-Z(n)-R; wherein each X, Y and Z is independently Met, Val, Thr, Tyr, Trp, Ser, Ala or Gly; each R is independently H or an amino-protecting group; and each n is independently 0 or 1.
FILED Tuesday, August 19, 2008
APPL NO 12/194248
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/8
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825088 von Andrian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The CBR Institute for Biomedical Research, Inc. (Boston, Massachusetts)
INVENTOR(S) Ulrich H. von Andrian (Brookline, Massachusetts);  Irina Mazo (Chestnut Hill, Massachusetts);  Jean-Marc Gauguet (Boston, Massachusetts)
ABSTRACT Methods for treating multiple myeloma with inhibitors of CXCR4 are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma.
FILED Monday, April 24, 2006
APPL NO 11/409927
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/11
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825089 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) National Jewish Health (Denver, Colorado)
INVENTOR(S) Gongyi Zhang (Denver, Colorado);  Hong-Bing Shu (Denver, Colorado);  Yingfang Liu (Denver, Colorado);  Liangguo Xu (Denver, Colorado)
ABSTRACT Disclosed are TALL-1 and TALL-1 receptor protein homologues (agonists and antagonists) designed based on the three-dimensional structure of sTALL-1, eBCMA and eBAFF-R; agonist homologues of APRIL; methods of using wild-type APRIL to inhibit the activity of TALL-1; compositions comprising such homologues, nucleic acid molecules encoding such homologues, and therapeutic methods of using such compounds and compositions. Also disclosed are crystalline complexes of sTALL-1 and sTALL-1 in complex with either BCMA or BAFF-R; models of three-dimensional structures of such crystalline complexes and related structures, methods of drug design using any portion of such structures; methods of design and/or identification of regulatory peptides derived from the such structures; compounds identified by drug design using such structures; and the use of such compounds in therapeutic compositions and methods.
FILED Thursday, October 24, 2002
APPL NO 10/281053
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825096 Moschel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Robert C. Moschel (Frederick, Maryland);  Matthew Karl Moschel, legal representative (Baltimore, Maryland);  Natalia A. Loktionova (Hershey, Pennsylvania);  Anthony E. Pegg (Hershey, Pennsylvania);  Gary T. Pauly (Frederick, Maryland)
ABSTRACT Disclosed are prodrugs of inactivators of O6-alkylguanine-DNA alkyltransferase (AGT). The prodrugs are cleavable by the β-glucuronidase enzyme, which is either administered to the patient or produced by necrotic tumor cells. The prodrugs are represented by the formula A-B-C, wherein A is a glucuronosyl residue linked through its 1-oxygen to the phenyl ring of B; B is a benzyloxycarbonyl group, optionally ring-substituted with one or more electron withdrawing groups; and C is an inactivator of AGT, e.g., a substituted or unsubstituted O6-benzylguanine or O6-benzyl-2′-deoxyguanosine. Also disclosed are additional inactivators of AGT, pharmaceutical compositions comprising an inactivator or prodrug and a pharmaceutically acceptable carrier, and a method of use of the inactivator or prodrug in enhancing the chemotherapeutic treatment of tumor cells in a mammal, e.g., a human, with an antineoplastic alkylating agent that causes cytotoxic lesions at the O6-position of guanine.
FILED Wednesday, March 07, 2007
APPL NO 11/683310
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/43
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US 07825098 Kahn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) Joslin Diabetes Center, Inc. (Boston, Massachusetts)
INVENTOR(S) C. Ronald Kahn (West Newton, Massachusetts);  Yu-Hua Tseng (Newton, Massachusetts)
ABSTRACT Described herein are methods for identifying and using inhibitors of Necdin function to promote brown adipose tissue (BAT) differentiation, thereby treating obesity.
FILED Tuesday, April 04, 2006
APPL NO 11/397514
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 07825126 Jacobson et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Kenneth A. Jacobson (Silver Spring, Maryland);  Bhalchandra V. Joshi (Rockville, Maryland);  Susanna Tchilibon (Jerusalem, Israel)
ABSTRACT Disclosed are (N)-methanocarba adenine nucleosides of the formula:
as highly potent A3 adenosine receptor agonists, pharmaceutical compositions comprising such nucleosides, and a method of use of these nucleosides, wherein R1-R6 are as defined in the specification. These nucleosides are contemplated for use in the treatment a number of diseases, for example, inflammation, cardiac ischemia, stroke, asthma, diabetes, and cardiac arrhythmias. The invention also provides compounds that are agonists of both A1 and A3 adenosine receptors for use in cardioprotection.
FILED Friday, September 02, 2005
APPL NO 11/574779
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/263.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825216 Burke, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  Georgetown University (Washington, District of Columbia)
INVENTOR(S) Terrence R. Burke, Jr. (Bethesda, Maryland);  Yang Gao (Branford, Connecticut);  Zhu-jun Yao (Shanghai, China PRC);  Dajun Yang (Gaithersburg, Maryland)
ABSTRACT The present invention provides phenylalanine derivatives that inhibit SH2 domain binding with a phosphoprotein. These derivatives include compounds of the formula: W—Y-(AA)n-Z wherein n is 0 to 15; Y is a phenylalanyl radical having a phenyl ring, an amine end, and a carboxyl end, the phenyl ring having one or more substituents, e.g., hydroxyl, carboxyl, formyl, carboxyalkyl, carboxyalkyloxy, dicarboxyalkyl, dicarboxyalkyloxy, dicarboxyhaloalkyl, dicarboxyhaloalkyloxy, and phosphonoalkyl, or phosphonohaloalkyl; W is a moiety attached to the nitrogen of Y and is, e.g., alkylcarbonyl, oxalyl, alkylaminooxalyl, arylaminooxalyl, arylalkylaminooxalyl, or alkoxyoxalyl; AA is an amino acid, the amine end of which is attached to the carboxyl end of Y; and Z is an arylalkylamino or arylheterocyclyl alkylamino; or a salt thereof; with the proviso that W is not arylalkylamino when the phenyl ring of phenylalanyl contains a phosphonoalkyl or phosphonohaloalkyl substituent at a position para to the alkylamido group and the ortho and meta positions are unsubstituted. The present invention further provides precursors suitable for preparing the phenylalanine derivatives and a method for the preparation of the precursors. The present invention further provides conjugates comprising a precursor and a conjugant that are covalently linked. These conjugates have biological and/or pharmacological properties.
FILED Wednesday, May 16, 2007
APPL NO 11/749499
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825217 Rowe
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) University of Kansas Medical Center (Kansas City, Kansas)
INVENTOR(S) Peter S. N. Rowe (Prairie Village, Kansas)
ABSTRACT Polypeptides for improving bone mineralization and/or phosphate update are provided. The peptides include a PHEX zinc binding domain and two ASARM binding domains.
FILED Friday, September 15, 2006
APPL NO 11/521684
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/324
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825226 Schultz et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Peter G. Schultz (La Jolla, California);  Lei Wang (San Diego, California);  Zhiwen Zhang (San Diego, California)
ABSTRACT Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
FILED Friday, October 26, 2007
APPL NO 11/978232
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/395
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825231 Wolfe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) Darren P. Wolfe (Pittsburgh, Pennsylvania);  Joseph C. Glorioso (Pittsburgh, Pennsylvania);  Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Darren P. Wolfe (Verona, Pennsylvania);  Joseph C. Glorioso (Fox Chapel, Pennsylvania);  David J. Fink (Ann Arbor, Michigan)
ABSTRACT The invention provides an expression cassette comprising a DNA sequence encoding amino acids 1-99 of human preproenkephalin, a DNA sequence encoding a precursor of a carboxy-amidated peptide flanked by dibasic cleavage sites and optionally a DNA sequence encoding a marker protein (such as Enhanced Green Fluorescent Protein (GFP)) all in operable linkage and under control of a promoter. Where the encoded precursor of a carboxy-amidated peptide is an agonist for an opioid receptor, the invention further provides a method of treating neuropathic pain by administering the gene transfer vector comprising such an expression cassette to a patient. The invention also provides a method for detecting a peptide having a desired effect comprising introducing a library of DNA sequences encoding one or more precursors of carboxy-amidated peptides into host cells; expressing the carboxy-amidated peptides encoded in the library to provide expression products; and screening from the polypeptide expression products for the desired effect.
FILED Thursday, June 01, 2006
APPL NO 11/445837
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825267 Koide et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Pittsburgh-of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Kazunori Koide (Pittsburgh, Pennsylvania);  Brian J. Albert (Pittsburgh, Pennsylvania);  Ananthapadmanabhan Sivaramakrishnan (Jamestown, North Carolina)
ABSTRACT The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.
FILED Saturday, September 08, 2007
APPL NO 11/852278
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
549/415
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825270 Aneja
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Nutrimed Biotech (Ithaca, New York)
INVENTOR(S) Raijindra Aneja (Ithaca, New York)
ABSTRACT Embodiments of the invention relate to natural and synthetic inositolphospholipid (IPL) materials, their preparation and applications. They provide compositions of the parent IPL comprising phosphatidylinositol (PI), PI-phosphates (phosphoinositides) and derivatives and analogues, and a process for their production starting from natural IPL. The embodiments further provide functional derivatives of PI for biomedical applications including a platform for drug design and delivery to therapeutic targets in the phosphoinositide mediated cellular signaling and allied cascades. The embodiments pertain to IPL having absolute stereo-structure. The embodiments further pertain to unique IPL and PI product compositions for defined applications, particularly pharmaceutical compositions for prophylaxis and treatment of diseases related to aberrant cellular and nuclear signaling mediated by PI and PI derived phosphates, and associated phosphoinositide specific enzymes including PI-PLC and PI 3-kinase.
FILED Wednesday, December 20, 2006
APPL NO 11/613679
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
554/78
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US 07825374 Cotter et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Robert James Cotter (Baltimore, Maryland);  Benjamin D. Gardner (Colton, California);  Robert D. English (Galveston, Texas);  Serguei A. Ilchenko (Solon, Ohio)
ABSTRACT A tandem mass spectrometer includes a linear time-of-flight mass analyzer and curved field reflectron mass analyzer. The curved-field reflectron mass analyzer is disposed at an end of the linear time-of-flight mass analyzer such that ions having a plurality of ion masses formed in the linear time-of-flight analyzer such that ions having a plurality of ion masses formed in the linear time-of-flight analyzer enter the curved-field reflectron mass analyzer. The tandem mass spectrometer also includes a mass selection gate disposed between the time-of-flight mass analyzer and the curved-field reflectron mass analyzer. The mass selection gate selects an ion mass from the plurality of ion masses. Furthermore, the tandem mass spectrometer also includes a dissociating component located in a path of the ions formed in the linear time-of-flight analyzer. The dissociating component causes dissociation of the ions into a plurality of ion fragments.
FILED Monday, February 23, 2004
APPL NO 10/546323
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/287
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825667 Fang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Microwave Imaging Systems Technologies, Inc. (Hanover, New Hampshire)
INVENTOR(S) Qianqian Fang (Somerville, Massachusetts);  Paul M. Meaney (Hanover, New Hampshire);  Keith D. Paulsen (Hanover, New Hampshire)
ABSTRACT A microwave imaging process, and a system controlled by an associated software product, illuminate a target with microwaves from a transmitting antenna. Receiving antennas receive microwaves scattered by the target, and form microwave data. The illumination and receiving repeat over multiple transmitting antennas and multiple microwave frequencies. The microwave data is processed to form permittivity and conductivity images by selecting a background dispersion model for permittivity and conductivity. Permittivity and conductivity dispersion coefficients are determined, and permittivity and conductivity distributions are calculated, for each of the microwave frequencies. Forward solutions at multiple frequencies are determined from property distributions, and a dispersion coefficient based Jacobian matrix is determined. Dispersion coefficient updates are determined using the microwave data, and the dispersion coefficients are updated. Permittivity and conductivity distributions are recalculated for each of the frequencies, and the forward solutions are determined at multiple frequencies from property distributions.
FILED Wednesday, December 21, 2005
APPL NO 11/316641
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Measuring and testing
324/637
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826595 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina (Chapel Hill, North Carolina)
INVENTOR(S) Zejian Liu (Chapel Hill, North Carolina);  Otto Z. Zhou (Chapel Hill, North Carolina);  Jianping Lu (Chapel Hill, North Carolina)
ABSTRACT Micro-focus field emission x-ray sources and related methods are provided. A micro-focus field emission x-ray source can include a field emission cathode including a film with a layer of electron field emitting materials patterned on a conducting surface. Further, the x-ray source can include a gate electrode for extracting field emitted electrons from the cathode when a bias electrical field is applied between the gate electrode and the cathode. The x-ray source can also include an anode. Further, the x-ray source can include an electrostatic focusing unit between the gate electrode and anode. The electrostatic focusing unit can include multiple focusing electrodes that are electrically separated from each other. Each of the electrodes can have an independently adjustable electrical potential. A controller can be configured to adjust at least one of the electrical potentials of the focusing electrodes and to adjust a size of the cathode.
FILED Tuesday, March 13, 2007
APPL NO 11/717590
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/122
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826629 Miles et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) State University New York (Binghamton, New York)
INVENTOR(S) Ronald N. Miles (Newark Valley, New York);  F. Levent Degertekin (Decatur, Georgia)
ABSTRACT A microphone having an optical component for converting the sound-induced motion of the diaphragm into an electronic signal using a diffraction grating. The microphone with inter-digitated fingers is fabricated on a silicon substrate using a combination of surface and bulk micromachining techniques. A 1 mm×2 mm microphone diaphragm, made of polysilicon, has stiffeners and hinge supports to ensure that it responds like a rigid body on flexible hinges. The diaphragm is designed to respond to pressure gradients, giving it a first order directional response to incident sound. This mechanical structure is integrated with a compact optoelectronic readout system that displays results based on optical interferometry.
FILED Thursday, January 19, 2006
APPL NO 11/335137
ART UNIT 2614 — Optics
CURRENT CPC
Electrical audio signal processing systems and devices
381/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826894 Musallam et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Sam Musallam (Pasadena, California);  Richard A. Andersen (La Canada, California);  Brian D. Corneil (London, Canada);  Bradley Greger (Van Nuys, California);  Hansjorg Scherberger (Zurich, Switzerland)
ABSTRACT In an embodiment, the invention relates to neural prosthetic devices in which control signals are based on the cognitive activity of the prosthetic user. The control signals may be used to control an array of external devices, such as prosthetics, computer systems, and speech synthesizers. Data obtained from monkeys' movement intentions were recorded, decoded with a computer algorithm, and used to position cursors on a computer screen. Not only the intended goals, but also the value of the reward the animals expected to receive at the end of each trial, were decoded from the recordings. The results indicate that brain activity related to cognitive variables can be a viable source of signals for the control of a cognitive-based neural prosthetic.
FILED Tuesday, March 22, 2005
APPL NO 11/086534
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/544
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826977 Garty et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Guy Garty (Dobbs Ferry, New York);  Gerhard Randers-Pehrson (Ossining, New York);  David J. Brenner (New York, New York);  Oleksandra V. Lyulko (New York, New York)
ABSTRACT Systems and methods for high-speed image scanning are disclosed herein One aspect of the invention is directed to a method for high speed image scanning. The method for high speed image scanning includes adjusting an object using a positioning element; directing a portion of an image of the object toward a sensor by positioning a first mirror relative to the object, and by positioning a second mirror relative to the object and the first mirror; controlling the positioning element, the position of the first mirror and the position of the second mirror using a processor; and detecting the portion of the image of the object using the sensor positioned relative to the first mirror and the second mirror. In accord with this method, the first mirror directs the portion of the image of the object in a first direction and the second mirror directs the portion of the image of the object in a second direction.
FILED Friday, August 24, 2007
APPL NO 11/895470
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826982 Zheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Children's Hospital Medical Center (Cincinnati, Ohio);  The Research Foundation of State University of New York (Stony Brook, New York)
INVENTOR(S) Yi Zheng (Cincinnati, Ohio);  Nicolas Nassar (Coram, New York);  Karlheinz R. Skowronek (Huntington Station, New York)
ABSTRACT The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity, along with uses for the compounds including screening for compounds which recognize Rac GTPase, and methods of treating pathological conditions associated or related to a Rho family GTPase, including Rac. The preferred embodiments also relate to methods of using such compounds, or derivatives thereof, e.g., in therapeutics, diagnostics, and as research tools.
FILED Monday, July 31, 2006
APPL NO 11/496959
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/27
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07824150 Kimmel et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) Keith D Kimmel (Jupiter, Florida);  Jack W. Wilson, Jr. (Palm Beach Gardens, Florida)
ABSTRACT A turbine airfoil, such as a rotor blade or a stator vane, for a gas turbine engine, the airfoil formed as a shell and spar construction with a plurality of dog bone struts each mounted within openings formed within the shell and spar to allow for relative motion between the spar and shell in the airfoil chordwise direction while also forming a seal between adjacent cooling channels. The struts provide the seal as well as prevent bulging of the shell from the spar due to the cooling air pressure.
FILED Friday, May 15, 2009
APPL NO 12/467009
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824473 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Joseph T. Hupp (Northfield, Illinois);  Omar K. Farha (Evanston, Illinois);  Alexander M. Spokoyny (Evanston, Illinois);  Karen L. Mulfort (Chicago, Illinois)
ABSTRACT Disclosed herein are metal-organic frameworks of metals and boron rich ligands, such as carboranes and icosahedral boranes. Methods of synthesizing and using these materials in gas uptake are disclosed.
FILED Friday, July 25, 2008
APPL NO 12/180074
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Gas separation: Processes
095/116
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US 07824495 White et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Terry L. White (Knoxville, Tennessee);  Felix L. Paulauskas (Knoxville, Tennessee);  Timothy S. Bigelow (Knoxville, Tennessee)
ABSTRACT A system to continuously produce fully carbonized or graphitized carbon fibers using microwave-assisted plasma (MAP) processing comprises an elongated chamber in which a microwave plasma is excited in a selected gas atmosphere. Fiber is drawn continuously through the chamber, entering and exiting through openings designed to minimize in-leakage of air. There is a gradient of microwave power within the chamber with generally higher power near where the fiber exits and lower power near where the fiber enters. Polyacrylonitrile (PAN), pitch, or any other suitable organic/polymeric precursor fibers can be used as a feedstock for the inventive system. Oxidized or partially oxidized PAN or pitch or other polymeric fiber precursors are run continuously through a MAP reactor in an inert, non-oxidizing atmosphere to heat the fibers, drive off the unwanted elements such as oxygen, nitrogen, and hydrogen, and produce carbon or graphite fibers faster than conventionally produced carbon fibers.
FILED Wednesday, November 09, 2005
APPL NO 11/270065
ART UNIT 1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating apparatus
118/718
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824574 White et al.
FUNDED BY
Department of Energy (DOE)
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Eltron Research and Development (Boulder, Colorado)
INVENTOR(S) James H. White (Boulder, Colorado);  Erick J. Schutte (Thornton, Colorado);  Sara L. Rolfe (Loveland, Colorado)
ABSTRACT Processes are disclosure which comprise alternately contacting an oxygen-carrying catalyst with a reducing substance, or a lower partial pressure of an oxidizing gas, and then with the oxidizing gas or a higher partial pressure of the oxidizing gas, whereby the catalyst is alternately reduced and then regenerated to an oxygenated state. In certain embodiments, the oxygen-carrying catalyst comprises at least one metal oxide-containing material containing a composition having one of the following formulas: (a) CexByB′zB″Oδ, wherein B=Ba, Sr, Ca, or Zr; B′=Mn, Co, or Fe; B″=Cu; 0.01<x<0.99; 0<y<0.6; 0<z<0.5; and 1<δ<2.2; (b) SrvLawBxB′yB″zOδ, wherein B=Co or Fe; B′=Al or Ga; B″=Cu; 0.01<v<1.4; 0.1<w<1.6; 0.1<x<1.9; 0.1<y<0.9; 0<z<2.2; and 3<δ<5.5).
FILED Thursday, September 20, 2007
APPL NO 11/858564
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/373
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824651 Zhamu et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Nanotek Instruments, Inc. (Dayton, Ohio)
INVENTOR(S) Aruna Zhamu (Centerville, Ohio);  Jinjun Shi (Columbus, Ohio);  Jiusheng Guo (Centerville, Ohio);  Bor Z. Jang (Centerville, Ohio)
ABSTRACT The present invention provides a method of exfoliating a layered material (e.g., graphite and graphite oxide) to produce nano-scaled platelets having a thickness smaller than 100 nm, typically smaller than 10 nm. The method comprises (a) dispersing particles of graphite, graphite oxide, or a non-graphite laminar compound in a liquid medium containing therein a surfactant or dispersing agent to obtain a stable suspension or slurry; and (b) exposing the suspension or slurry to ultrasonic waves at an energy level for a sufficient length of time to produce separated nano-scaled platelets. The nano-scaled platelets are candidate reinforcement fillers for polymer nanocomposites. Nano-scaled graphene platelets are much lower-cost alternatives to carbon nano-tubes or carbon nano-fibers.
FILED Tuesday, May 08, 2007
APPL NO 11/800728
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/448
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US 07824884 Harris et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Paul Harris (Carnation, Washington);  Alfredo Lopez de Leon (Davis, California);  Michael Rey (Davis, California);  Hanshu Ding (Davis, California);  Elena Vlasenko (Davis, California)
ABSTRACT The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
FILED Thursday, April 27, 2006
APPL NO 11/413022
ART UNIT 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824927 Morozov et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) George Mason Intellectual Properties, Inc. (Fairfax, Virginia)
INVENTOR(S) Victor Morozov (Manassas, Virginia);  Charles L. Bailey (Cross Junction, Virginia);  Melissa R. Evanskey (Potomac Falls, Virginia)
ABSTRACT Analytes using an active assay may be detected by introducing an analyte solution containing a plurality of analytes to a lacquered membrane. The lacquered membrane may be a membrane having at least one surface treated with a layer of polymers. The lacquered membrane may be semi-permeable to nonanalytes. The layer of polymers may include cross-linked polymers. A plurality of probe molecules may be arrayed and immobilized on the lacquered membrane. An external force may be applied to the analyte solution to move the analytes towards the lacquered membrane. Movement may cause some or all of the analytes to bind to the lacquered membrane. In cases where probe molecules are presented, some or all of the analytes may bind to probe molecules. The direction of the external force may be reversed to remove unbound or weakly bound analytes. Bound analytes may be detected using known detection types.
FILED Wednesday, April 05, 2006
APPL NO 11/397905
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/532
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825064 Wong et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Michael S. Wong (Houston, Texas);  Israel E. Wachs (Bethlehem, Pennsylvania);  William V. Knowles (Pearland, Texas)
ABSTRACT A process for making a porous catalyst, comprises a) providing an aqueous solution containing a nanoparticle precursor, b) forming a composition containing nanoparticles, c) adding a first catalytic component or precursor thereof and a pore-forming agent to the composition containing nanoparticles and allowing the first catalytic component, the pore-forming agent, and the nanoparticles form an organic-inorganic structure, d) removing water from the organic-inorganic structure; and e) removing the pore-forming agent from the organic-inorganic structure so as to yield a porous catalyst.
FILED Thursday, June 03, 2004
APPL NO 10/558917
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/305
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825226 Schultz et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Peter G. Schultz (La Jolla, California);  Lei Wang (San Diego, California);  Zhiwen Zhang (San Diego, California)
ABSTRACT Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
FILED Friday, October 26, 2007
APPL NO 11/978232
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/395
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825294 Altier et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) Pioneer Hi-Bred International, Inc. (Johnston, Iowa);  E.I. du Pont de Nemours and Company (Wilmington, Delaware);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Daniel J. Altier (Granger, Iowa);  I. A. Ellanskaya (Kyiv, Ukraine);  Jacob T. Gilliam (Norwalk, Iowa);  Jennie Hunter-Cevera (Elliott City, Maryland);  James K Presnail (Avondale, Pennsylvania);  Eric Schepers (Port Deposit, Maryland);  Carl R. Simmons (Des Moines, Iowa);  Tamas Torok (Richmond, California);  Nasser Yalpani (Johnston, Iowa)
ABSTRACT Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.
FILED Thursday, July 16, 2009
APPL NO 12/503952
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/279
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US 07825391 Shumlak et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The University of Washington (Seattle, Washington)
INVENTOR(S) Uri Shumlak (Seattle, Washington);  Raymond Golingo (Seattle, Washington);  Brian A. Nelson (Mountlake Terrace, Washington)
ABSTRACT Various mechanisms are provided relating to plasma-based light source that may be used for lithography as well as other applications. For example, a device is disclosed for producing extreme ultraviolet (EUV) light based on a sheared plasma flow. The device can produce a plasma pinch that can last several orders of magnitude longer than what is typically sustained in a Z-pinch, thus enabling the device to provide more power output than what has been hitherto predicted in theory or attained in practice. Such power output may be used in a lithography system for manufacturing integrated circuits, enabling the use of EUV wavelengths on the order of about 13.5 nm. Lastly, the process of manufacturing such a plasma pinch is discussed, where the process includes providing a sheared flow of plasma in order to stabilize it for long periods of time.
FILED Thursday, April 10, 2008
APPL NO 12/101083
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/504.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825735 Wessendorf
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Kurt O. Wessendorf (Albuquerque, New Mexico)
ABSTRACT A transimpedance amplifier system is disclosed which simultaneously generates a low-gain output signal and a high-gain output signal from an input current signal using a single transimpedance amplifier having two different feedback loops with different amplification factors to generate two different output voltage signals. One of the feedback loops includes a resistor, and the other feedback loop includes another resistor in series with one or more diodes. The transimpedance amplifier system includes a signal linearizer to linearize one or both of the low- and high-gain output signals by scaling and adding the two output voltage signals from the transimpedance amplifier. The signal linearizer can be formed either as an analog device using one or two summing amplifiers, or alternately can be formed as a digital device using two analog-to-digital converters and a digital signal processor (e.g. a microprocessor or a computer).
FILED Tuesday, October 20, 2009
APPL NO 12/582318
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Amplifiers
330/308
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825760 Bird et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
National High Magnetic Field Laboratory (NHMFL)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Mark D. Bird (Tallahassee, Florida);  Jack Toth (Tallahassee, Florida)
ABSTRACT An electromagnet having a conical bore. The conical bore is created by wrapping a conductor around a conically-offset helix. The cross sectional area of the conductor can be varied in order to maintain a desired current carrying capacity along the helix. A single element can be used as the conductor. The conductor can also be created by stacking a series of specially-shaped plates analogous to prior art Bitter-disks.
FILED Wednesday, October 08, 2008
APPL NO 12/287278
ART UNIT 2832 — Semiconductors/Memory
CURRENT CPC
Electricity: Magnetically operated switches, magnets, and electromagnets
335/299
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825819 Muralidharan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Govindarajan Muralidharan (Knoxville, Tennessee);  Charles L. Britton (Alcoa, Tennessee);  James Pearce (Lenoir City, Tennessee);  Usha Jagadish (Knoxville, Tennessee);  Vinod K. Sikka (Oak Ridge, Tennessee)
ABSTRACT A low-power shock sensing system includes at least one shock sensor physically coupled to a chemical storage tank to be monitored for impacts, and an RF transmitter which is in a low-power idle state in the absence of a triggering signal. The system includes interface circuitry including or activated by the shock sensor, wherein an output of the interface circuitry is coupled to an input of the RF transmitter. The interface circuitry triggers the RF transmitter with the triggering signal to transmit an alarm message to at least one remote location when the sensor senses a shock greater than a predetermined threshold. In one embodiment the shock sensor is a shock switch which provides an open and a closed state, the open state being a low power idle state.
FILED Tuesday, November 11, 2008
APPL NO 12/268657
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/665
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826065 Okandan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Murat Okandan (Edgewood, New Mexico);  Peter Schwindt (Albuquerque, New Mexico)
ABSTRACT An atomic magnetometer is disclosed which utilizes an optical cavity formed from a grating and a mirror, with a vapor cell containing an alkali metal vapor located inside the optical cavity. Lasers are used to magnetically polarize the alkali metal vapor and to probe the vapor and generate a diffracted laser beam which can be used to sense a magnetic field. Electrostatic actuators can be used in the magnetometer for positioning of the mirror, or for modulation thereof. Another optical cavity can also be formed from the mirror and a second grating for sensing, adjusting, or stabilizing the position of the mirror.
FILED Tuesday, July 15, 2008
APPL NO 12/173547
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/521
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826379 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles Jens Archer (Rochester, Minnesota);  Kurt Walter Pinnow (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota);  Brian Edward Smith (Rochester, Minnesota)
ABSTRACT An apparatus, program product and method enable nodal fault detection by sequencing communications between all system nodes. A master node may coordinate communications between two slave nodes before sequencing to and initiating communications between a new pair of slave nodes. The communications may be analyzed to determine the nodal fault.
FILED Monday, February 07, 2005
APPL NO 11/052658
ART UNIT 2476 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/242
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826504 Chen et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Houtong Chen (Los Alamos, New Mexico);  Willie John Padilla (Newton, Massachusetts);  Richard Douglas Averitt (Newton, Massachusetts);  John F. O'Hara (Los Alamos, New Mexico);  Mark Lee (Albuquerque, New Mexico)
ABSTRACT Metamaterial structures are taught which provide for the modulation of terahertz frequency signals. Each element within an array of metamaterial (MM) elements comprises multiple loops and at least one gap. The MM elements may comprise resonators with conductive loops and insulated gaps, or the inverse in which insulated loops are present with conductive gaps; each providing useful transmissive control properties. The metamaterial elements are fabricated on a semiconducting substrate configured with a means of enhancing or depleting electrons from near the gaps of the MM elements. An on to off transmissivity ratio of about 0.5 is achieved with this approach. Embodiments are described in which the MM elements incorporated within a Quantum Cascade Laser (QCL) to provide surface emitting (SE) properties.
FILED Friday, April 03, 2009
APPL NO 12/418064
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/43.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826975 Maranas et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Costas D. Maranas (Port Matilda, Pennsylvania);  Anthony P. Burgard (State College, Pennsylvania);  Priti Pharkya (State College, Pennsylvania)
ABSTRACT A computer-assisted method for identifying functionalities to add to an organism-specific metabolic network to enable a desired biotransformation in a host includes accessing reactions from a universal database to provide stoichiometric balance, identifying at least one stoichiometrically balanced pathway at least partially based on the reactions and a substrate to minimize a number of non-native functionalities in the production host, and incorporating the at least one stoichiometrically balanced pathway into the host to provide the desired biotransformation. A representation of the metabolic network as modified can be stored.
FILED Thursday, August 26, 2004
APPL NO 10/929091
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827024 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles J. Archer (Rochester, Minnesota);  Michael A. Blocksome (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota);  Brian E. Smith (Rochester, Minnesota)
ABSTRACT Methods, parallel computers, and computer program products are disclosed for low latency, high bandwidth data communications between compute nodes in a parallel computer. Embodiments include receiving, by an origin direct memory access (‘DMA’) engine of an origin compute node, data for transfer to a target compute node; sending, by the origin DMA engine of the origin compute node to a target DMA engine on the target compute node, a request to send (‘RTS’) message; transferring, by the origin DMA engine, a predetermined portion of the data to the target compute node using memory FIFO operation; determining, by the origin DMA engine whether an acknowledgement of the RTS message has been received from the target DMA engine; if the an acknowledgement of the RTS message has not been received, transferring, by the origin DMA engine, another predetermined portion of the data to the target compute node using a memory FIFO operation; and if the acknowledgement of the RTS message has been received by the origin DMA engine, transferring, by the origin DMA engine, any remaining portion of the data to the target compute node using a direct put operation.
FILED Wednesday, May 09, 2007
APPL NO 11/746333
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/24
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827385 Almasi et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Gheorghe Almasi (Ardsley, New York);  Charles J. Archer (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota);  Brian E. Smith (Rochester, Minnesota)
ABSTRACT A parallel computer comprises a plurality of compute nodes organized into at least one operational group for collective parallel operations. Each compute node is assigned a unique rank and is coupled for data communications through a global combining network. One compute node is assigned to be a logical root. A send buffer and a receive buffer is configured. Each element of a contribution of the logical root in the send buffer is contributed. One or more zeros corresponding to a size of the element are injected. An allreduce operation with a bitwise OR using the element and the injected zeros is performed. And the result for the allreduce operation is determined and stored in each receive buffer.
FILED Thursday, August 02, 2007
APPL NO 11/832918
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Processing architectures and instruction processing
712/16
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827391 Blumrich et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Matthias A. Blumrich (Ridgefield, Connecticut);  Valentina Salapura (Chappaqua, New York)
ABSTRACT An apparatus and method are disclosed for single-stepping coherence events in a multiprocessor system under software control in order to monitor the behavior of a memory coherence mechanism. Single-stepping coherence events in a multiprocessor system is made possible by adding one or more step registers. By accessing these step registers, one or more coherence requests are processed by the multiprocessor system. The step registers determine if the snoop unit will operate by proceeding in a normal execution mode, or operate in a single-step mode.
FILED Tuesday, June 26, 2007
APPL NO 11/768857
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Processing architectures and instruction processing
712/227
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07823467 Taya et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Minoru Taya (Mercer Island, Washington);  Jin Wang (Seattle, Washington);  Chunye Xu (Seattle, Washington);  Yasuo Kuga (Seattle, Washington)
ABSTRACT An electroactive polymer is used to produce a tactile sensor. The electroactive polymer (EAP) includes a sheet of an ion-exchange membrane having opposite surfaces on which are plated gold electrodes. The EAP is formed to have a dome-shape with a plurality of sensing electrodes circumferentially disposed around an outer surface of the dome. A flexible polymer underlying the EAP supports it and prevents a force applied to the tactile sensor from inverting the dome. The sensor electrodes produce separate output signals indicative of different vector components of an applied force acting on the tactile sensor, so that a direction of the force can be determined. Vias provided in the electrodes are electrically coupled to a flexible circuit that conveys the output signals externally from the sensing electrodes for use and further processing. A plurality of the tactile sensors can be formed as an array on an ion-exchange membrane.
FILED Monday, December 08, 2008
APPL NO 12/330396
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/862.625
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824462 Webster et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Thomas J. Webster (Lafayette, Indiana);  Jeremiah U. Ejiofor (Union, New Jersey)
ABSTRACT A composition for use as a prosthetic biomaterial and associated method. The biomaterial exhibits cytocompatibility, mechanical functionality and osteoblast adhesion between the implant and interfacing surface. The biomaterial is metallic, has a grain size less than about 500 nanometers and has a surface roughness of less than about 800 nm rms.
FILED Friday, March 26, 2004
APPL NO 10/550439
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/245
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824467 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Gabriella Metraux (Evanston, Illinois)
ABSTRACT A method of preparing metal nanoprisms having a unimodal size distribution and a predetermined thickness. The present method also allows control over nanoprism edge length.
FILED Wednesday, June 29, 2005
APPL NO 11/629830
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/371
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824582 Marks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Hu Kang (Evanston, Illinois)
ABSTRACT Unconventional twisted π-electron system electro-optic (EO) chromophores/compounds, compositions and related device structures. Crystallographic analysis of several non-limiting chromophores reveals, for instance, large ring-ring dihedral twist angles and a highly charge-separated zwitterionic structure in the ground state, in both solution phase and solid-state.
FILED Friday, March 24, 2006
APPL NO 11/389429
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/586
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824620 Bau et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Haim H. Bau (Swarthmore, Pennsylvania);  Byong M. Kim (East Brunswick, New Jersey)
ABSTRACT Disclosed are methods for fabricating integrated nano-scale and micro-scale structures. Also disclosed are carbon nanopipettes, shovels, and sheets made by these methods. Nano-scale and micro-scale structures fabricated by the disclosed methods are useful in a variety of application, for example, nanoelectrodes, functionalized probes for chemical and biological sensing, nanopipettes for fluid and macromolecule transfer, and devices for the dispensing and deposition of nanodrops.
FILED Wednesday, September 21, 2005
APPL NO 11/231425
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07825199 Matyjaszewski et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania);  Scott G. Gaynor (Pittsburgh, Pennsylvania);  Hyun-jong Paik (Pittsburgh, Pennsylvania);  Tomislav Pintauer (Pittsburgh, Pennsylvania);  Jeff Pyun (Pittsburgh, Pennsylvania);  Jian Qiu (Pittsburgh, Pennsylvania);  Mircea Teodorescu (Bucharest, Romania);  Jianhui Xia (Pittsburgh, Pennsylvania);  Xuan Zhang (Woburn, Massachusetts);  Peter J. Miller (Imperial, Pennsylvania)
ABSTRACT Further improvements have been made in processes for controlled polymerization of free radically (co)polymerizable monomers mediated by a transition metal complex participating in a redox reaction which involves transfer of a radically transferable atom or group to and from an initiator or dormant polymer and the growing active polymer chain ends. Two improvements involve the choice of counterion in the transition metal complex. In one improvement the transition metal is held in close conjunction with a solid support through interaction with a counterion directly attached to the support. This cognition also allows for improvements in catalyst utilization including catalyst recovery and recycle. In another improvement, particularly suitable for controlled polymerization of certain monomers with an expanded range of transition metals, the function of counterion and ligand in the development of the transition metal based catalyst is superseded by use of salt containing a soluble organic counterion. These and other process improvements have been employed to prepare an extended range of novel polymeric materials and novel processes for the preparation of functional polymers including a novel catalytic Atom Transfer Coupling Reaction.
FILED Thursday, March 23, 2000
APPL NO 09/534827
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
526/90
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US 07825543 Karalis et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Aristeidis Karalis (Cambridge, Massachusetts);  Andre B. Kurs (Cambridge, Massachusetts);  Robert Moffatt (Reston, Virginia);  John D. Joannopoulos (Belmont, Massachusetts);  Peter H. Fisher (Cambridge, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT Disclosed is an apparatus for use in wireless energy transfer, which includes a first resonator structure configured to transfer energy non-radiatively with a second resonator structure over a distance greater than a characteristic size of the second resonator structure. The non-radiative energy transfer is mediated by a coupling of a resonant field evanescent tail of the first resonator structure and a resonant field evanescent tail of the second resonator structure.
FILED Wednesday, March 26, 2008
APPL NO 12/055963
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electrical transmission or interconnection systems
37/104
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US 07825903 Anastas et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Immersion Corporation (San Jose, California)
INVENTOR(S) George V. Anastas (San Carlos, California);  Neil T. Olien (Montreal, Canada)
ABSTRACT A method and apparatus for generating haptic effects for a touch panel or other interface device employs a touch-sensitive panel, a display and an actuator. The actuator includes a first structural element and a second structural element, a biasing element and two magnetic devices. The first magnetic device is configured to be carried by the first structural element and the second magnetic device is configured to be carried by the second structural element. The first structural element is coupled to a touch-sensitive panel and the second structural element may be coupled to the display or to a relatively fixed item. The biasing element couples the first and second structural elements together and deforms to facilitate a movement between the first and second structural elements. The actuator provides haptic effects by facilitating relative movement between the first and second structural elements.
FILED Thursday, May 12, 2005
APPL NO 11/128717
ART UNIT 2629 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Computer graphics processing and selective visual display systems
345/173
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826061 Sanders
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Scott T. Sanders (Madison, Wisconsin)
ABSTRACT A high-speed absorption spectrographic system employs a slit-less spectroscope to obtain high-resolution, high-speed spectrographic data of combustion gases in an internal combustion engine allowing precise measurement of gas parameters including temperature and species concentration.
FILED Thursday, August 20, 2009
APPL NO 12/544313
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/451
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US 07826975 Maranas et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Costas D. Maranas (Port Matilda, Pennsylvania);  Anthony P. Burgard (State College, Pennsylvania);  Priti Pharkya (State College, Pennsylvania)
ABSTRACT A computer-assisted method for identifying functionalities to add to an organism-specific metabolic network to enable a desired biotransformation in a host includes accessing reactions from a universal database to provide stoichiometric balance, identifying at least one stoichiometrically balanced pathway at least partially based on the reactions and a substrate to minimize a number of non-native functionalities in the production host, and incorporating the at least one stoichiometrically balanced pathway into the host to provide the desired biotransformation. A representation of the metabolic network as modified can be stored.
FILED Thursday, August 26, 2004
APPL NO 10/929091
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826983 Alwan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Majd Alwan (Charlottesville, Virginia);  Glenn S. Wasson (Crozet, Virginia);  Pradip N. Sheth (Charlottesville, Virginia);  Alexandre Ledoux (Charlottesville, Virginia);  Cunjun Huang (Sunnyvale, California)
ABSTRACT Various implementations are disclosed for an instrumented mobility assistance device, such as an instrumented walker. The device includes an attached sensor that is operable to convert an operational action of a user of the mobility assistance device into a sensor signal. A use analyzer is operable to relate the sensor signal to a contact attribute associated with a contact of the user of the mobility assistance device with an underlying surface. The use analyzer is further operable to determine a gait characteristic of the user, based on the contact attribute. The sensor may include a force or moment sensor. The contact attribute may include a foot-initial contact, or a foot-off contact. In this way, gait characteristics of the user may be determined during normal operation of the instrumented device. Also, the sensor may be used to determine a stability measure associated with the device.
FILED Friday, January 05, 2007
APPL NO 11/650361
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/33
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07824247 Bar-Cohen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Yoseph Bar-Cohen (Seal Beach, California);  Mireca Badescu (Arcadia, California);  Xiaoqi Bao (San Gabriel, California);  Zenshea Chang (Irvine, California);  Stewart Sherrit (La Crescenta, California)
ABSTRACT A hand-held drilling device, and method for drilling using the device, has a housing, a transducer within the housing, with the transducer effectively operating at ultrasonic frequencies, a rotating motor component within the housing and rigid cutting end-effector rotationally connected to the rotating motor component and vibrationally connected to the transducer. The hand-held drilling device of the present invention operates at a noise level of from about 50 decibels or less.
FILED Friday, June 01, 2007
APPL NO 11/756819
ART UNIT 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Abrading
451/165
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US 07824574 White et al.
FUNDED BY
Department of Energy (DOE)
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Eltron Research and Development (Boulder, Colorado)
INVENTOR(S) James H. White (Boulder, Colorado);  Erick J. Schutte (Thornton, Colorado);  Sara L. Rolfe (Loveland, Colorado)
ABSTRACT Processes are disclosure which comprise alternately contacting an oxygen-carrying catalyst with a reducing substance, or a lower partial pressure of an oxidizing gas, and then with the oxidizing gas or a higher partial pressure of the oxidizing gas, whereby the catalyst is alternately reduced and then regenerated to an oxygenated state. In certain embodiments, the oxygen-carrying catalyst comprises at least one metal oxide-containing material containing a composition having one of the following formulas: (a) CexByB′zB″Oδ, wherein B=Ba, Sr, Ca, or Zr; B′=Mn, Co, or Fe; B″=Cu; 0.01<x<0.99; 0<y<0.6; 0<z<0.5; and 1<δ<2.2; (b) SrvLawBxB′yB″zOδ, wherein B=Co or Fe; B′=Al or Ga; B″=Cu; 0.01<v<1.4; 0.1<w<1.6; 0.1<x<1.9; 0.1<y<0.9; 0<z<2.2; and 3<δ<5.5).
FILED Thursday, September 20, 2007
APPL NO 11/858564
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/373
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07826878 Alfano et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Research Foundation of City University of New York (New York, New York)
INVENTOR(S) Robert R. Alfano (Bronx, New York);  Min Xu (Woodside, New York);  Mohammed Alrubaiee (New York, New York);  Swapan Kumar Gayen (Marlboro, New Jersey)
ABSTRACT Disclosed is a system and a method for detecting the presence of one or more objects in a turbid medium, the method including: illuminating at least a portion of the turbid medium with incident light having at least one wavelength which interacts with the one or more objects contained in the turbid medium differently than the incident light interacts with the turbid medium; measuring light that emerges from the turbid medium; and detecting and locating the one or more objects using Independent Component Analysis (ICA) of the emergent light from the turbid medium. The present invention is useful for medical applications, such as for finding and locating, a tumor(s) in body organs, or excised tissues. Moreover, the present invention can be used to locate objects in obscuring medium, such as, mines in shallow coastal water, a plane in fog, military targets under fog, smoke or cloud cover.
FILED Wednesday, December 07, 2005
APPL NO 11/296831
ART UNIT 3737 — Optics
CURRENT CPC
Surgery
6/310
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US 07827459 Zhou et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Xiaoming Zhou (Sunnyvale, California);  John S. Baras (Potomac, Maryland)
ABSTRACT The present invention relates to an improved communications protocol which increases the efficiency of transmission in return channels on a multi-channel slotted Alohas system by incorporating advanced error correction algorithms, selective retransmission protocols and the use of reserved channels to satisfy the retransmission requests.
FILED Monday, January 08, 2007
APPL NO 11/651314
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/749
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 07823321 Tomich et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Commerce (Washington, District of Columbia)
INVENTOR(S) Stan D. Tomich (Seattle, Washington);  Marjory E. Clarke (Seattle, Washington);  John H. Harms (Seattle, Washington);  Jennifer A. Hempelmann (Seattle, Washington)
ABSTRACT The DNA Sampling Hook is a significant improvement on a method of obtaining a tissue sample from a live fish in situ from an aquatic environment. A tissue sample taken from a live fish can be used for DNA analyses, which can identify the species of fish, as well as the unique individual fish. Taking a small tissue sample without bringing the fish to the surface is important as it allows for observing the fish community without harming the individual fish by inducing barotrauma or other stresses associated with bringing a fish up from depth, which can be lethal to the animal. These tissue samples are obtained by hook and line methods and do not capture or traumatize the fish resulting in a non-lethal and non-destructive method of observing fish individuals and species. The DNA Sampling Hook is specifically designed to virtually eliminate a condition called double bites, in which more than one individual fish gives up tissue to the same hook. It is also designed to protect the tissue sample in an enclosed manner and the device can be reused repeatedly for a total overall reduction in cost for programs requiring extensive numbers of tissue samples for DNA analysis.
FILED Monday, January 28, 2008
APPL NO 12/021091
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Fishing, trapping, and vermin destroying
043/43.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824949 Sambandan et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Sanjiv Sambandan (Palo Alto, California);  William S. Wong (San Carlos, California);  Rene A. Lujan (Sunnyvale, California);  Scott J. Limb (Palo Alto, California)
ABSTRACT A method of forming a sensor array. The method includes depositing a source/drain contact layer; depositing a semiconductor layer on the source/drain contact layer; and patterning the source/drain contact layer and the semiconductor layer substantially simultaneously, wherein the patterned semiconductor layer forms part of a sensor of the sensor array.
FILED Friday, December 21, 2007
APPL NO 11/963008
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/59
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827029 Kaplan et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Research and Development Activity (ARDA)
APPLICANT(S)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Ronald Kaplan (Palo Alto, California);  Richard Crouch (Cupertino, California);  Michael Tepper (Seattle, Washington);  Daniel Bobrow (Palo Alto, California)
ABSTRACT Techniques are presented to determine user-interest sensitive notes. User selected passages, user interest information, condensation transformations and optional meaning distortion constraints are identified. User foci expressed by the selected passages are determined based on the similarity of the elements in the selected passages to elements in the user interest information. User sensitive notes are determined by selectively applying the condensation transformations to the selected passages to preferentially retain user foci while eliding less salient information. Meaning distortions constraints are optionally applied in conjunction with condensation transformations or in creating the condensation transformations in order to reduce the likelihood of distorting the meaning of the passage.
FILED Tuesday, November 30, 2004
APPL NO 10/999793
ART UNIT 2626 — Selective Visual Display Systems
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/9
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07826365 Tang et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Ao (Kevin) Tang (Pasadena, California);  Zhen Liu (Tarrytown, New York);  Honghui (Cathy) Xia (Briarcliff Manor, New York);  Li Zhang (Yorktown Heights, New York)
ABSTRACT Resource allocations in stream data processing systems are performed to allocate the resources in a cost-effective manner by formulating the resource allocation problem as a linear program. For a problem with a single output, a backward algorithm or method is used that produces an optimal solution in linear time. For a problem with multiple outputs and the network has a tree structure, a backward shrink algorithm or method is used to provide an optimal solution in linear time. These algorithms are fully distributed, they require only local exchange of parameters between neighboring nodes, and are adaptive to the dynamic changes in network conditions and flow rate fluctuations.
FILED Tuesday, September 12, 2006
APPL NO 11/519764
ART UNIT 2464 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/235
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827408 Gehringer et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Director of the National Security Agency (Washington, District of Columbia)
INVENTOR(S) Nicholas E. Gehringer (Jessup, Maryland);  Patricia P. Greene (Columbia, Maryland)
ABSTRACT A device for and method of authenticated encryption by concatenating a first user-datum with a second datum, concatenating the first datum with a third datum, encrypting the results, concatenating the encrypted results, concatenating the result with a message and a fifth user-definable datum, hashing the result, concatenating the result with the message, dividing the result into blocks, concatenating the first datum with a sixth datum, generating key-stream blocks from the result using a block cipher in counter mode, combining the blocks and key-stream blocks, concatenating the result with the first datum and the fifth datum, and transmitting the result to a recipient. The recipient extracts the hash value from the received ciphertext, generates a hash value from the first through fifth datums and plaintext derived from the ciphertext, and compares the two. If they match then the plaintext and fifth datum are as the sender intended.
FILED Tuesday, July 10, 2007
APPL NO 11/825934
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Support
713/170
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07824574 White et al.
FUNDED BY
Department of Energy (DOE)
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Eltron Research and Development (Boulder, Colorado)
INVENTOR(S) James H. White (Boulder, Colorado);  Erick J. Schutte (Thornton, Colorado);  Sara L. Rolfe (Loveland, Colorado)
ABSTRACT Processes are disclosure which comprise alternately contacting an oxygen-carrying catalyst with a reducing substance, or a lower partial pressure of an oxidizing gas, and then with the oxidizing gas or a higher partial pressure of the oxidizing gas, whereby the catalyst is alternately reduced and then regenerated to an oxygenated state. In certain embodiments, the oxygen-carrying catalyst comprises at least one metal oxide-containing material containing a composition having one of the following formulas: (a) CexByB′zB″Oδ, wherein B=Ba, Sr, Ca, or Zr; B′=Mn, Co, or Fe; B″=Cu; 0.01<x<0.99; 0<y<0.6; 0<z<0.5; and 1<δ<2.2; (b) SrvLawBxB′yB″zOδ, wherein B=Co or Fe; B′=Al or Ga; B″=Cu; 0.01<v<1.4; 0.1<w<1.6; 0.1<x<1.9; 0.1<y<0.9; 0<z<2.2; and 3<δ<5.5).
FILED Thursday, September 20, 2007
APPL NO 11/858564
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compositions
252/373
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07824651 Zhamu et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Nanotek Instruments, Inc. (Dayton, Ohio)
INVENTOR(S) Aruna Zhamu (Centerville, Ohio);  Jinjun Shi (Columbus, Ohio);  Jiusheng Guo (Centerville, Ohio);  Bor Z. Jang (Centerville, Ohio)
ABSTRACT The present invention provides a method of exfoliating a layered material (e.g., graphite and graphite oxide) to produce nano-scaled platelets having a thickness smaller than 100 nm, typically smaller than 10 nm. The method comprises (a) dispersing particles of graphite, graphite oxide, or a non-graphite laminar compound in a liquid medium containing therein a surfactant or dispersing agent to obtain a stable suspension or slurry; and (b) exposing the suspension or slurry to ultrasonic waves at an energy level for a sufficient length of time to produce separated nano-scaled platelets. The nano-scaled platelets are candidate reinforcement fillers for polymer nanocomposites. Nano-scaled graphene platelets are much lower-cost alternatives to carbon nano-tubes or carbon nano-fibers.
FILED Tuesday, May 08, 2007
APPL NO 11/800728
ART UNIT 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemistry of inorganic compounds
423/448
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07826922 Brandt et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Bruce A. Brandt (Gainesville, Virginia);  Jay David Fadely (Palmetto, Florida)
ABSTRACT Apparatus and methods consistent with the present invention provide for processing mailpiece information in a mail processing device using sorter application software. In one embodiment, a mail processing device uses the sorter application software to communicate with an identification code server. In this embodiment, different types of mail processing devices can use the common sorter application software to communicate with the same or different identification code servers.
FILED Thursday, August 30, 2007
APPL NO 11/896147
ART UNIT 3653 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Data processing: Generic control systems or specific applications
7/223
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07827048 Wilson et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) James D. Wilson (Collierville, Tennessee);  Jacquelynn Estes (Warrenton, Virginia)
ABSTRACT A survey is placed into an envelope containing an address label and a tracking indicia. The address label indicates an old address of a recipient. The envelope containing the survey is routed through a delivery system. The delivery system is configured to sense the tracking indicia as it passes through the elements of the delivery system thus tracking the movement of the envelope through the delivery system. The envelope containing the survey is sent through the delivery system to the plant supporting the old address. The recipient, however, no longer resides at the old address and now resides at a new address. The envelope containing the survey is forwarded through the delivery system to the plant supporting the new address. Once the recipient receives and completes the survey, survey is sent to the system operator for analysis.
FILED Thursday, September 06, 2001
APPL NO 10/362123
ART UNIT 3629 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/7
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07824690 Reddy et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Sanjay M. Reddy (College Station, Texas);  Blanca M. Lupiani (College Station, Texas)
ABSTRACT An effective vaccine for Marek's disease may be prepared using a viral agent which is a Marek's disease virus unable to express a functional meq protein. This viral agent is effective to elicit an immune response in a chicken to very virulent strains of Marek's disease virus without causing a significant degree of pathogenicity in the inoculated bird. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent with a pharmaceutically acceptable carrier or diluent.
FILED Friday, May 04, 2007
APPL NO 11/800475
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/205.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 07825092 Vesely
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  United States Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) David L. Vesely (Tampa, Florida)
ABSTRACT Disclosed is a method of inhibiting the growth of a cancer cell using Dendroaspis natriuretic peptide (DNP), isolated from the Green Mamba snake venom with similar structure to ANP, with or without four cardiac natriuretic peptides i.e., atrial natriuretic peptide (ANP), vessel dilator, long acting natriuretic peptide (LANP), and kaliuretic peptide. Dose-response curves revealed a significant (p<0.0001) decrease in human glioblastoma cells with each ten-fold increase in concentration from 1 μM to 100 μM of four of the cardiac peptide hormones. There was an 75%, 68%, 67%, and 65% elimination within 24 hours of glioblastoma cells secondary to vessel dilator, kaliuretic peptide, ANP, and LANP, respectively (p<0.0001) while DNP had no significant effect at 1 μM (2% decrease), and 10 μM (7%), but 100 μM caused a (17%) decrease (p<0.05). Three days after treatment with these peptide hormones, the cancer cells began to proliferate again. These same hormones decreased DNA synthesis from 65% to 87% (p<0.00001).
FILED Friday, August 03, 2007
APPL NO 11/833757
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07825199 Matyjaszewski et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania);  Scott G. Gaynor (Pittsburgh, Pennsylvania);  Hyun-jong Paik (Pittsburgh, Pennsylvania);  Tomislav Pintauer (Pittsburgh, Pennsylvania);  Jeff Pyun (Pittsburgh, Pennsylvania);  Jian Qiu (Pittsburgh, Pennsylvania);  Mircea Teodorescu (Bucharest, Romania);  Jianhui Xia (Pittsburgh, Pennsylvania);  Xuan Zhang (Woburn, Massachusetts);  Peter J. Miller (Imperial, Pennsylvania)
ABSTRACT Further improvements have been made in processes for controlled polymerization of free radically (co)polymerizable monomers mediated by a transition metal complex participating in a redox reaction which involves transfer of a radically transferable atom or group to and from an initiator or dormant polymer and the growing active polymer chain ends. Two improvements involve the choice of counterion in the transition metal complex. In one improvement the transition metal is held in close conjunction with a solid support through interaction with a counterion directly attached to the support. This cognition also allows for improvements in catalyst utilization including catalyst recovery and recycle. In another improvement, particularly suitable for controlled polymerization of certain monomers with an expanded range of transition metals, the function of counterion and ligand in the development of the transition metal based catalyst is superseded by use of salt containing a soluble organic counterion. These and other process improvements have been employed to prepare an extended range of novel polymeric materials and novel processes for the preparation of functional polymers including a novel catalytic Atom Transfer Coupling Reaction.
FILED Thursday, March 23, 2000
APPL NO 09/534827
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Synthetic resins or natural rubbers
526/90
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. Agency for International Development (USAID) 

US 07824383 Sokal et al.
FUNDED BY
U.S. Agency for International Development (USAID)
APPLICANT(S)
ASSIGNEE(S) Family Health International (Durham, North Carolina)
INVENTOR(S) David C. Sokal (Durham, North Carolina);  Carol L. Joanis (Raleigh, North Carolina);  George A. M. Butterworth (Pittsboro, North Carolina);  James D. Reed (Raleigh, North Carolina);  Robert A. Johnson (Turnersville, New Jersey)
ABSTRACT A vaginal drug delivery system includes a device formed of porous material that holds a flowable therapeutic formulation. The device, preferably in a soft, prewetted state, is inserted into the vagina to reside typically at or near the cervix where it continuously releases the flowable therapeutic formulation through its outer surface which is in contact with the vaginal surfaces. In operation, the flowable therapeutic formulation migrates via capillary forces from a reservoir that is centrally located in the device and through a covering that envelopes the reservoir.
FILED Thursday, June 14, 2007
APPL NO 11/763085
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
64/285
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 02, 2010.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2010/fedinvent-patents-20101102.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital