FedInvent™ Patents

Patent Details for Tuesday, June 14, 2011 

This page was updated on Monday, March 27, 2023 at 02:01 AM GMT

Department of Defense (DOD) 

US 07958718 Berchtold et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) Alliant Techsystems Inc. (Minneapolis, Minnesota)
INVENTOR(S) L. Don Berchtold (Brigham City, Utah);  Ralph S. Tappan (Brigham City, Utah)
ABSTRACT A multiple-stage solid rocket motor is operated in a manner designed to control its mass discharge profile. This is accomplished by providing means for igniting one stage and then igniting a subsequent stage while the first continues to burn.
FILED Friday, July 07, 1989
APPL NO 07/376813
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Power plants
060/204
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958719 Brady
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Brian Blaise Brady (Seal Beach, California)
ABSTRACT A fuel injector system for combustion engines and motors, such as pulsed bipropellant thrusters, includes noncircular fuel and oxidizer injectors at the ends of respective dribble channels for controlling the mixture ratio of the propellants passing into a combustion chambers for maintaining a desire or ideal mixture ratio as determined by the cross-sectional area of the injectors well suited for pulse combustion fuel injector systems.
FILED Wednesday, March 28, 2007
APPL NO 11/729331
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/257
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958777 Davies et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) Daniel O. Davies (Palm City, Florida);  Ross H Peterson (Palm Beach Gardens, Florida)
ABSTRACT A thermal mechanical fatigue test rig for testing a coating, such as a thermal barrier coating, under high temperature and pressure to simulate the actual operating environment of the coating. The test rig includes a combustor to produce a hot gas flow, a hollow test specimen on which the coating is placed, and a sapphire vessel that encloses the hollow test specimen to form a hot gas flow path over the coating. The sapphire vessel is clear so that the coating can be observed by a camera during the testing. An exhaust plenum is formed around the sapphire vessel to collect the exhaust form the hot gas flow in which additional cooling air and water for quenching can be injected to reduce the temperature of the hot gas flow prior to discharge from the test rig.
FILED Sunday, October 04, 2009
APPL NO 12/573133
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/112.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958780 Corder et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) David A. Corder (Tucson, Arizona);  Kevin W. Elsberry (Tucson, Arizona)
ABSTRACT A wind tunnel testing technique or method involves using feedback to position control surfaces of a model so that there is substantially no moment on the model for its given orientation to the airstream. The model is mounted on a sting that allows change in orientation of the model relative to the airstream. A balance is used to provide data regarding the forces and/or moments on the model. This data on forces and/or moments is used in one or more feedback loops to position the control surfaces of the model so that there are substantially no moments on the model. This may be done automatically, with a controller automatically controlling the position of the control surfaces to zero out the moments on the model. The use of the method may allow faster determination of model characteristics, such as determination of the trim envelope of the model.
FILED Thursday, December 03, 2009
APPL NO 12/630218
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/147
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958823 Sawka
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Wayne N. Sawka (Reno, Nevada)
ABSTRACT A thruster stack assembly and method for manufacturing the same is provided. The thruster stack assembly includes a plurality of grain elements having a common core region (e.g., a channel or passageway), where each grain element comprises a volume of electrically ignitable propellant. The thruster stack assembly further includes electrodes associated with the plurality of grain elements, the electrodes adapted for selectively igniting the plurality of grain elements. In one example, one or more of the grain elements may be ignited and combusted without igniting or damaging adjacent grain elements of the stack. The core region serves to channel combustion gases and exhaust from the thruster stack. Multiple stacks may be assembled together to form three-dimensional thruster arrays.
FILED Friday, December 16, 2005
APPL NO 11/305742
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/291
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958829 Kane et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Ricky G. Kane (Aberdeen, Maryland);  Mark T Ward (Abingdon, Maryland)
ABSTRACT A sabot with exactly two complimentary halves, wherein each half portion comprises teeth configured to interlock with teeth of the other half portion. The sabot may further comprise a semi-circular groove configured in the teeth of each half portion. Also, each half portion may comprise at least one indented conical end. Preferably, on each half portion, the teeth are spaced apart from the at least one indented conical end. Moreover, each half portion may comprise translucent polycarbonate material. Furthermore, each half portion may be adapted to flush mount together to form a substantially cylindrical configuration when the teeth are interlocked. Additionally, the sabot may further comprise a semi-circular groove configured in the teeth of each half portion, wherein the semi-circular groove extends to the at least one indented conical end.
FILED Friday, November 02, 2007
APPL NO 11/934292
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/523
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958862 Carter et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) SECCO2 Engines, Inc. (Pleasanton, California)
INVENTOR(S) Preston Henry Carter (Bend, Oregon);  Kenney Ray Spence (Bend, Oregon)
ABSTRACT The present invention relates to the field of combustion engines and more specifically to a rotary positive displacement combustor engine. The device employs a scroll compressor and a scroll expander with an orbital shaft displaced between the compressor and expander supplying a means and link for compressing fluids within the scroll compressor and disposing the fluid within the scroll expander within which an ignition source is placed at strategic points within a pair of first isolated zones of the orbiting scroll expander generating a highly efficient process for capturing mechanical and thermal energy from combustion.
FILED Friday, December 07, 2007
APPL NO 11/999748
ART UNIT 3748 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Internal-combustion engines
123/235
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958870 Bonfigli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Delphi Technologies Holdings S.arl (Troy, Michigan)
INVENTOR(S) Fabrizio A. Bonfigli (Mont pres Chambord, France);  Philippe Legrand (St. Gervais la Foret, France);  Emmanuel Autret (Blois, France);  Robert A. D'Aubyn (Bath, United Kingdom);  Simon H. Phillips (Coleford, United Kingdom)
ABSTRACT A fuel lance assembly for an engine comprises: a fuel lance to be received in a passage provided in a cylinder head and a connection arrangement comprising an inlet adapter for securing the fuel lance within the passage. The fuel lance comprises a tubular member of constant external diameter, arranged to be received, in use, within the passage and having a first end being shaped for cooperation with a seating surface of a fuel injector of the engine, and a second end being shaped for cooperation with the inlet adapter, and being provided with a bore therethrough to define a fuel flow path between the first end and the second end of the fuel lance. The inlet adapter is provided with an attachment system for engaging a compatible attachment system of the cylinder head, and has a proximal region for receiving a high pressure fuel pipe, and wherein the inlet adapter has a distal region provided with an opening being adapted to receive the second end of the fuel lance. A fuel lance and a fuel supply line arrangement are also provided.
FILED Wednesday, November 12, 2008
APPL NO 12/291671
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Internal-combustion engines
123/470
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958906 Cardenas-Valencia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Andres M. Cardenas-Valencia (Tampa, Florida);  Jay Dlutowski (Safety Harbor, Florida);  Michelle Cardenas (Tampa, Florida);  John Bumgarner (Clearwater, Florida);  Weidong Wang (Oldsmar, Florida);  Larry Langebrake (Seminole, Florida)
ABSTRACT In accordance with an embodiment of the present invention, a thermally induced single-use valve is provided including a silicon wafer having a top surface and a bottom surface and at least one cavity formed in the bottom surface of the wafer, a thermally deformable membrane suspended across the cavity on the top surface of the wafer and at least one resistive element patterned on top of the thermally deformable membrane.
FILED Wednesday, April 11, 2007
APPL NO 11/734090
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/72
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958932 Chaudhry et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Fopat LLC (Dayton, Ohio)
INVENTOR(S) Anil R. Chaudhry (Xenia, Ohio);  Robert Dzugan (Cincinnati, Ohio);  Richard M. Harrington (Cincinnati, Ohio);  Faurice D. Neece (Lyndurst, Ohio);  Nipendra P. Singh (Pepper Pike, Ohio)
ABSTRACT A foam material comprises a liquid polymer and a liquid isocyanate which is mixed to make a solution that is poured, injected or otherwise deposited into a corresponding mold. A reaction from the mixture of the liquid polymer and liquid isocyanate inside the mold forms a thermally collapsible foam structure having a shape that corresponds to the inside surface configuration of the mold and a skin that is continuous and unbroken. Once the reaction is complete, the foam pattern is removed from the mold and may be used as a pattern in any number of conventional casting processes.
FILED Thursday, July 03, 2008
APPL NO 12/167546
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal founding
164/516
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959058 Crane et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Roger M. Crane (Arnold, Maryland);  Robert DeNale (Frederick, Maryland);  Harry E. Prince (Ijamsville, Maryland);  Timothy L. Dapp (Crofton, Maryland);  George C. Tunis, III (Berlin, Maryland)
ABSTRACT The present invention's composite-to-metal attachment methodology—bolt-free and adhesive-free—features the implementation of an intermediary structure containing metallic fibrous material. The intermediary structure couples a first adherend (which contains nonmetallic fibrous material) with a second adherend (which contains metallic nonfibrous material). The intermediary structure's fibrous attribute is availed of for effecting its co-cure attachment to the first adherend. The intermediary structure's metallic attribute is availed of for effecting its weld attachment to the second adherend. According to typical inventive practice, respective panels of the first adherend and the intermediary structure are arranged and connected so as to describe a stepped configuration at the interface between the first adherend and the intermediary structure. The first adherend and a first portion of the intermediary structure are co-impregnated with a uniform resinous system and are co-cured. A second portion of the intermediary structure is welded with respect to the second adherend.
FILED Friday, January 13, 2006
APPL NO 11/340009
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal fusion bonding
228/122.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959406 Suciu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Gabriel L. Suciu (Glastonbury, Connecticut);  Lawrence E. Portlock (Bethany, Connecticut);  Brian Merry (Andover, Connecticut)
ABSTRACT A gearbox assembly (90) closely couples a fan-turbine rotor assembly (25) and an axial compressor rotor (46) to reduce the overall engine length and minimizes the number of engine bearings.
FILED Wednesday, December 01, 2004
APPL NO 11/718424
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/62
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959407 Tholen
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Susan M. Tholen (Kennebunk, Maine)
ABSTRACT A blade outer air seal (BOAS) casting core has first and second end portions and a plurality of legs. Of these legs, first legs each have: a first end joining the first end portion; a main body portion; and a second end. Second legs each have: a second end joining the second end portion; a main body portion; and a first portion. At least one of the second legs may have its first end joining the core first end portion and a plurality of apertures in the main body portion. Alternatively, at least one of the first legs may have its second end joining the core second end portion and a plurality of apertures in its main body portion.
FILED Monday, December 07, 2009
APPL NO 12/632241
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959532 Suciu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Gabriel L. Suciu (Glastonbury, Connecticut);  Lawrence E. Portlock (Bethany, Connecticut);  Brian Merry (Andover, Connecticut)
ABSTRACT A hydraulic seal for a tip turbine engine includes an inner radial flange and an outer radial flange. The inner radial flange rotates relative to the outer radial seal section and the planet carrier face to prevent lubrication from entering into the air flow streams within the engine without additional engine assembly procedures.
FILED Wednesday, December 01, 2004
APPL NO 11/718519
ART UNIT 3655 — Material and Article Handling
CURRENT CPC
Planetary gear transmission systems or components
475/331
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959773 Hou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S)
ASSIGNEE(S) Lumimove, Inc. (St. Louis, Missouri)
INVENTOR(S) Shifeng Hou (Springfield, Missouri);  Von Howard M. Ebron (Republic, Missouri);  Yevgenia V. Ulyanova (Springfield, Missouri);  Sriram Viswanathan (Springfield, Missouri);  Patrick J. Kinlen (Fenton, Missouri)
ABSTRACT An electroactivated film that includes: a first electrode that is spaced apart from a second electrode, a water insoluble electrically conductive medium which is permeable to moisture and oxygen and which contacts both electrodes, an electrocatalyst which can be reversibly oxidized and reduced and which facilitates the production of a peroxide when an electrical potential is imposed across the electrodes, and optionally a peroxide-activating catalyst which converts the peroxide to an activated peroxide, wherein one or both electrodes have electrocatalyst immobilized thereupon.
FILED Thursday, June 26, 2008
APPL NO 12/215359
ART UNIT 1759 — Material and Article Handling
CURRENT CPC
Chemistry: Electrical and wave energy
24/252
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959861 Lopez et al.
FUNDED BY
Department of Defense (DOD)
Defense Intelligence Agency (DIA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Gabriel Lopez (Albuquerque, New Mexico);  Linnea Ista (Albuquerque, New Mexico);  Steven R J Brueck (Albuquerque, New Mexico);  Aurelio Evangelista Lara (Albuquerque, New Mexico);  Mangesh Bore (Albuquerque, New Mexico)
ABSTRACT Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
FILED Monday, April 14, 2008
APPL NO 12/102663
ART UNIT 3768 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/63
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959873 Roukes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Michael Roukes (Pasadena, California);  Hongxing Tang (Pasadena, California);  Jessica Arlett (S Pasadena, California);  James Maloney (Pasadena, California);  Benjamin Gudlewski (Pasadena, California)
ABSTRACT A biosensor is comprised of a free and a biofunctionalized recognition self-sensing nanocantilever, a dock adjacent to the ends of the nanocantilevers, and a gap between the nanocantilevers and dock. The self-sensing cantilevers each include a semiconductor piezoresistor defined in a pair of legs about which the cantilevers flex. A bias power or current is applied to the piezoresistor. The sensitivity of the cantilevers is optimized for a given ambient temperature and geometry of the cantilevers and dock by minimizing the force spectral density, SF, of the cantilevers to determine the optimum bias power, Pin. A sub-aN/√Hz force sensitivity is obtained by scaling down the dimensions of the cantilevers and supplying an optimum bias power as a function of temperature and geometry.
FILED Thursday, July 20, 2006
APPL NO 11/491394
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959974 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmotte, Illinois);  Yuhuang Wang (Evanston, Illinois);  Daniel Maspoch (L'Escala, Spain)
ABSTRACT Methods and articles providing for precise aligning, positioning, shaping, and linking of nanotubes and carbon nanotubes. An article comprising: a solid surface comprising at least two different surface regions including: a first surface region which comprises an outer boundary and which is adapted for carbon nanotube adsorption, and a second surface region which is adapted for preventing carbon nanotube adsorption, the second region forming an interface with the outer boundary of the first region, at least one carbon nanotube which is at least partially selectively adsorbed at the interface. The shape and size of the patterns on the surface and the length of the carbon nanotube can be controlled to provide for selective interfacial adsorption.
FILED Monday, December 04, 2006
APPL NO 11/633095
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/256
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960069 Crumm et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Adaptive Materials, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Aaron Crumm (Ann Arbor, Michigan);  Jonathan R. Rice (Whitmore Lake, Michigan)
ABSTRACT In one aspect, there is disclosed a high temperature composite insulation assembly for a fuel cell that includes a core portion having inner and outer surfaces. A temperature stable sealant is disposed on the outer surface of the core portion forming a gas retaining mechanically robust insulation assembly. In another aspect, there is disclosed a high temperature composite insulation assembly for a fuel cell that includes a core portion having inner and outer surfaces, and a reinforcing material disposed on the outer surface of the core portion. A temperature stable sealant is disposed on the outer surface of the core portion forming a gas retaining mechanically robust insulation assembly. In another aspect, there is disclosed a high temperature composite insulation assembly for a fuel cell that includes a core portion having inner and outer surfaces and a high temperature refractory material disposed on the inner surface of the core portion. A reinforcing material is disposed on the outer surface of the core portion and a temperature stable sealant is disposed on the outer surface of a core portion forming a gas retaining mechanically robust insulation assembly.
FILED Friday, February 02, 2007
APPL NO 11/670554
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/469
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960163 Dickson et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Georgetown University School of Medicine (Washington, District of Columbia)
INVENTOR(S) Robert B. Dickson (Silver Spring, Maryland);  Chen-Yong Lin (Falls Church, Virginia);  Michael Johnson (Rockville, Maryland);  Shaomeng Wang (Saline, Michigan);  Istvan Enyedy (Hamden, Connecticut)
ABSTRACT The invention is directed to a method of detecting a malignancy or a pre-malignant lesion in breast or other tissue, or a pathologic condition, by detecting the presence of single-chain or two-chain forms of matriptase in the tissue. The invention is further directed to a method of treating malignancies, which have the phenotype of matriptase production by administering a tumor formation inhibiting effective amount of concentrate of Bowman-Birk inhibitor (BBIC), or other matriptase inhibitor. The invention also is directed to nucleic acids encoding a matriptase protein or fragments thereof, and their use for structure elucidation and modeling to identify other inhibitors of matriptase, as well as to methods of identifying matriptase modulating agents, including activators and inhibitors.
FILED Friday, February 29, 2008
APPL NO 12/040467
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/219
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960198 Sankin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S) Semisouth Laboratories (Starkvilles, Mississippi)
INVENTOR(S) Igor Sankin (Starkville, Mississippi);  Joseph Neil Merrett (Starkville, Mississippi)
ABSTRACT A wide bandgap semiconductor device with surge current protection and a method of making the device are described. The device comprises a low doped n-type region formed by plasma etching through the first epitaxial layer grown on a heavily doped n-type substrate and a plurality of heavily doped p-type regions formed by plasma etching through the second epitaxial layer grown on the first epitaxial layer. Ohmic contacts are formed on p-type regions and on the backside of the n-type substrate. Schottky contacts are formed on the top surface of the n-type region. At normal operating conditions, the current in the device flows through the Schottky contacts. The device, however, is capable of withstanding extremely high current densities due to conductivity modulation caused by minority carrier injection from p-type regions.
FILED Thursday, June 28, 2007
APPL NO 11/819646
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/34
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960201 Cornfeld et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Space Vehicles Directorate Contracting Division (AFRL/RVK)
APPLICANT(S)
ASSIGNEE(S) Emcore Solar Power, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Arthur Cornfeld (Sandia Park, New Mexico);  Jacqueline Diaz (Albuquerque, New Mexico);  Tansen Varghese (Albuquerque, New Mexico)
ABSTRACT A method of manufacturing a solar cell by providing a first substrate; depositing on a first substrate a sequence of layers of semiconductor material forming a solar cell including at least a top subcell and a bottom subcell; mounting a surrogate substrate on top of the sequence of layers adjacent to the bottom subcell; removing the first substrate to expose the surface of the top subcell; removing the surrogate substrate; and holding the solar cell on a vacuum chuck to support it for subsequent fabrication operations, such as attaching interconnects to the solar cells to form an interconnected array.
FILED Thursday, January 29, 2009
APPL NO 12/362201
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/66
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960331 Grzyll et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Lawrence R. Grzyll (Merritt Island, Florida);  John A. Meyer (Palm Bay, Florida);  Dwight D. Back (Pembroke Pines, Florida)
ABSTRACT CFC replacement solvent compositions, methods of using the same and methods of making the same. These compositions meet or exceed the solvency, flammability, and compatibility requirements for CFC's while providing similar or improved environmental and toxicological properties. These solvent compositions have applications including, but not limited to, oxygen handling, refrigeration or heat pumps, electronics, implantable prosthetic devices, and optical equipment.
FILED Friday, August 15, 2008
APPL NO 12/192229
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Cleaning compositions for solid surfaces, auxiliary compositions therefor, or processes of preparing the compositions
510/407
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960372 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Shaomeng Wang (Saline, Michigan);  Haiying Sun (Ann Arbor, Michigan);  Dongguang Qin (Ann Arbor, Michigan);  Zaneta Nikolovska-Coleska (Ann Arbor, Michigan);  Jianfeng Lu (Ann Arbor, Michigan);  Su Qiu (Ann Arbor, Michigan);  Yuefeng Peng (Ann Arbor, Michigan);  Qian Cai (Ann Arbor, Michigan)
ABSTRACT The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis.
FILED Friday, May 04, 2007
APPL NO 11/800220
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960434 Turkson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  University of Central Florida Research Foundation, Inc. (Orlando, Florida);  H. Lee Moffitt Cancer Center and Research Institute (Tampa, Florida)
INVENTOR(S) James Turkson (Orlando, Florida);  Said M. Sebti (Tampa, Florida);  Wayne Guida (Saint Petersburg, Florida);  Man Lun Yip (Monrovia, California);  Nicholas J. Lawrence (Tampa, Florida);  Harshani Lawrence (Tampa, Florida);  Benjamin Greedy (Somerset, United Kingdom)
ABSTRACT The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S3I-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents.
FILED Monday, May 21, 2007
APPL NO 11/805217
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/518
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960471 Tan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Loon-Seng Tan (Centerville, Ohio);  Jong-Beom Baek (Junggu Ulsan, South Korea)
ABSTRACT A poly(ether-ketone) composite of the formula:
wherein CNF is carbon nanofibers and MWNT is multi-walled carbon nanotubes; wherein Ar represents ether-ketone repeating groups of the formula
wherein Q is —O— or —O—(CH2)n—O—, wherein n has a value of 2-12; wherein R is —H, —CH3, or —C2H5, m has a value of 1 or 2; wherein R′ is —H or —CH3; and wherein — denoted the presence of a direct C—C bond between Ar and CNF or MWNTg Also provided is a process for preparing the composite.
FILED Thursday, August 28, 2008
APPL NO 12/231423
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
524/877
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960509 Kaplan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) Trustees of Tufts College (, None);  The United States of America as represented by the Secretary of the Air Force AFMCLO/JAZ (Washington, District of Columbia);  The Board of Trustees of the University of Illinois (, None)
INVENTOR(S) David L. Kaplan (Concord, Massachusetts);  Jia Huang (Medford, Massachusetts);  Cheryl Wong Po Foo (Palo Alto, California);  Rajesh Naik (Dayton, Ohio);  Anne George (Chicago, Illinois)
ABSTRACT The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an organic-inorganic composite. These organic-inorganic composites can be constructed from the nano- to the macro-scale depending on the size of the fibrous protein domain used. The composites can also be loaded with other compounds (e.g. dyes, drugs, enzymes) depending on the goal for the materials, to further enhance function. This can be achieved during assembly of the materials or during the mineralization step in materials formation.
FILED Tuesday, January 17, 2006
APPL NO 11/794934
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960540 Trent et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Congressionally Directed Medical Research Programs (CDMRP)
APPLICANT(S)
ASSIGNEE(S) Advanced Cancer Therapeutics, LLC (Louisville, Kentucky)
INVENTOR(S) John O. Trent (Louisville, Kentucky);  Paula J. Bates (Louisville, Kentucky);  Donald M. Miller (Louisville, Kentucky)
ABSTRACT Compositions and methods for modulating tumor proliferation in an individual are provided. The methods employ nucleolin-binding agents, such as aptamers. The aptamers of the present invention can be used to modulate the proliferation of malignant, dysplastic, hyperproliferative, and/or metastatic cells through interference with molecular interactions and functions of nucleolin in the tumor cell.
FILED Wednesday, October 31, 2007
APPL NO 11/982427
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960548 Pento et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Ohio State University Research Foundation (Columbus, Ohio);  The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) J. Thomas Pento (Norman, Oklahoma);  Pui-Kai Li (Galloway, Ohio);  Robert W. Brueggemeier (Dublin, Ohio);  John C. Hackett (Dublin, Ohio)
ABSTRACT Compounds and methods for treating, inhibiting, or delaying the onset of cancer in a subject by administering a therapeutically effective amount of a keratinocyte growth factor receptor tyrosine kinase (KGFR TK) inhibitor to the subject in need of such treatment. Also provided are compounds and methods for the treating, inhibiting, or delaying the onset of metastasis in a subject with cancer by administering a therapeutically effective amount of a KGFR TK inhibitor to the subject in need of such treatment.
FILED Monday, May 01, 2006
APPL NO 11/414890
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
546/62
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960555 Emrick
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Todd S. Emrick (Deerfield, Massachusetts)
ABSTRACT Versatile Group VIII metathesis catalysts, as can be used in a range of polymerization reactions and other chemical methodologies.
FILED Monday, January 12, 2009
APPL NO 12/319826
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
548/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960753 Conway et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Joshua A. Conway (Redondo Beach, California);  Ryan A. Stevenson (Maple Valley, Washington);  Jon V. Osborn (Thousand Oaks, California)
ABSTRACT A surface plasmon polaritron activated semiconductor device uses a surface plasmon wire that functions as an optical waveguide for fast communication of a signal and functions as a energy translator using a wire tip for translating the optical signal passing through the waveguide into plasmon-polaritron energy at a connection of the semiconductor device, such as a transistor, to activate the transistor for improved speed of communications and switching for preferred use in digital systems.
FILED Tuesday, September 11, 2007
APPL NO 11/900346
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/104
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960804 Ebel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as respresented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) John L. Ebel (Beavercreek, Ohio);  Rebecca Cortez (Schenectady, New York);  Kevin D. Leedy (Centerville, Ohio);  Richard E. Strawser (Greenville, Ohio);  Donald E. Strawser, legal representative (Greenville, Ohio)
ABSTRACT A latching zip-mode actuated mono wafer MEMS switch especially suited to capacitance coupled signal switching of microwave radio frequency signals is disclosed. The single wafer fabrication process used for the switch employs sacrificial layers and liquid removal of these layers in order to also provide needed permanent physical protection for an ultra fragile switch moving arm member. Latched operation of the achieved MEMS switch without use of conventional holding electrodes or magnetic fields is also achieved. Fabrication of a single MEMS switch is disclosed however large or small arrays may be achieved.
FILED Thursday, May 08, 2008
APPL NO 12/152129
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/415
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960934 Benson et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Dwayne M. Benson (Chandler, Arizona);  James Neil Quitmeyer (Chandler, Arizona);  William Daugherty (Tucson, Arizona)
ABSTRACT A fault-tolerant position feedback filter may be used in an actuation control system to limit the authority of a first position signal, should the first position signal become erroneous, and thereby prevent a postulated runaway condition of an acuator. The filter includes a difference function, a limited integrator, and a summer. The difference function supplies a first position error signal representative of a mathematical difference between a first position signal and a combined position signal. The limited integrator supplies an integrated position error signal that is limited in magnitude to a predetermined limit. The summer supplies the combined position error signal that is representative of a mathematical sum of the integrated position error signal and the second position signal.
FILED Tuesday, September 23, 2008
APPL NO 12/236326
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Motive power systems
318/564
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961025 Rylov
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Sergey Vladimirovich Rylov (White Plains, New York)
ABSTRACT In one illustrative embodiment, an apparatus for a current-mode phase rotator with partial input phase switching comprises a mixer, wherein the mixer is a four quadrant current-mode mixer comprised of four interpolation buffers, wherein each interpolation buffer receives as input a clock phase from a set of four equidistant clock phases, and a set of two-output current-steering digital to analog converters that supply tail currents to the mixer wherein a first digital to analog converter has additional switches to connect each of two outputs to one of two polarities of a given clock while each remaining digital to analog converter has no additional switches and has two outputs supplying current only to two different polarities of a same clock phase wherein steering the current during incremental rotation about a phase circle defines an octagonal shaped phase envelope.
FILED Tuesday, August 04, 2009
APPL NO 12/535112
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Miscellaneous active electrical nonlinear devices, circuits, and systems
327/231
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961134 Ranney et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kenneth I. Ranney (Rockville, Maryland);  Jeffrey Sichina (Ocean View, Delaware)
ABSTRACT Self-calibrating an automatic, surveillance-based change detection system operating on noisy imagery comprises detecting a first image co-registered with a second image, wherein the first image and the second image each comprise pixels of a noisy image of a scene; detecting the second image co-registered with the first image, wherein co-registration of the first image with the second image comprises pixels from different images corresponding to a same location within the scene; producing a calibration factor based on the co-registered images; producing a modified ratio of pixel values corresponding to the first image and the second image from the same location within the scene; and comparing the modified ratio to a pre-determined threshold ratio value.
FILED Monday, September 21, 2009
APPL NO 12/563571
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/25.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961138 Govoni
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as respresented by the Secretary of the Army. (Washington, District of Columbia)
INVENTOR(S) Mark A. Govoni (Abingdon, Maryland)
ABSTRACT A detector apparatus, detection system, and method are provided for determining optimum operational angles based on the statistical correlation of wavelength-specific electromagnetic propagation and surface interaction. These techniques can be used within the radar community in both military and commercial radar applications for airborne radar system users to determine optimum operational depression angles based on the purpose of the effort, the operational frequency, and the terrain-type to be encountered. The method requires the user to interface with a standard computer equipped with the commercially available MATLAB® software package where the operation is presented as a graphic user interface (GUI) that once invoked allows the user to set specific parameters corresponding to the desired terrain type. Upon doing so, the algorithms are exercised and the results are displayed in a series of figures identifying the optimum operational angles.
FILED Tuesday, August 25, 2009
APPL NO 12/584589
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/74
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961369 Khoshnevisan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Teledyne Licensing, LLC (Thousand Oaks, California)
INVENTOR(S) Mohsen Khoshnevisan (Newbury Park, California);  Ray C. Delcher (Oxnard, California);  Mark D. Ewbank (Newbury Park, California);  Arthur Chiou (Thousand Oaks, California);  William R. Christian (Newbury Park, California);  Randolph L. Hall (Newbury Park, California)
ABSTRACT A laser beam steering apparatus includes a beam steering cell with an adjustable shape, with the cell having opposing Fabry-Perot filters, and a steering mechanism coupled to the cell to adjust its shape so that the direction of a laser beam emitted from the cell is changed in response to a change in the cell shape.
FILED Wednesday, September 28, 2005
APPL NO 11/238590
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Optical: Systems and elements
359/223.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961631 Chen et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Shyh-Kwei Chen (Chappaqua, New York);  Michail Vlachos (Tarrytown, New York);  Kun-Lung Wu (Yorktown Heights, New York);  Philip Shi-lung Yu (Chappaqua, New York)
ABSTRACT Systems and methods for the identification of correlated burst events among two or more data streams, given one or more specific query time spans are disclosed. Also broadly contemplated is the act of finding, from one or more data streams, those streams that have correlated burst events with another given data stream within a time span.
FILED Tuesday, July 22, 2008
APPL NO 12/177379
ART UNIT 2462 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961642 Agrawal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Dakshi Agrawal (Monsey, New York);  Alina Beygelzimer (White Plains, New York);  Bong Jun Ko (Harrington, New Jersey);  Mudhakar Srivatsa (White Plains, New York)
ABSTRACT A method of determining the state of network links based on differences in corresponding distance-vectors in a sequence routing table updates, and a network management system performing the method. The network management system comprises least one monitoring apparatus adapted to determine the state of network links. The monitoring apparatus may be a router in the network adapted to determine link status, or a personal computer or server peered with a router and configured to determine the state of network links based on differences in corresponding distance-vectors in a sequence of routing table updates.
FILED Thursday, May 29, 2008
APPL NO 12/129269
ART UNIT 2472 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/252
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961922 Spence et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas);  Southern Methodist University (Dallas, Texas)
INVENTOR(S) Jeffrey S. Spence (Forney, Texas);  Patrick S. Carmack (Dallas, Texas);  Qihua Lin (Irving, Texas);  Richard F. Gunst (Dallas, Texas);  William R. Schucany (Dallas, Texas);  Robert W. Haley (Dallas, Texas)
ABSTRACT Systems and methods for processing medical image data with increased sensitivity to facilitate comparisons among groups of subjects are disclosed herein. In one embodiment, a method comprises receiving a first three-dimensional image comprising a plurality of voxels, reducing a regional trend within the three-dimensional image, computing a semivariogram for a region of interest, defining at least one block of spatially correlated voxels, calculating voxel weights for each voxel within the at least one block, and determining a block average count and variance for the at least one block.
FILED Thursday, May 31, 2007
APPL NO 11/756454
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961988 Krug et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) William P. Krug (Bellevue, Washington);  Jocelyn Y. Takayesu (Tacoma, Washington);  Michael Hochberg (Pasadena, California);  Thomas W. Baehr-Jones (Pasadena, California);  Eric Y. Chan (Mercer Island, Washington);  Larry Dalton (Silverdale, Washington);  Axel Scherer (Laguna Beach, California)
ABSTRACT A system and method are disclosed for a rapidly tunable wavelength selective ring resonator. An embodiment of a voltage-tunable wavelength selective ring resonator includes a ring-shaped waveguide formed on a semiconductor substrate, an electro-optic cladding layer formed over the ring-shaped waveguide, and voltage applying means for applying a voltage across the electro-optic cladding layer. The ring-shaped waveguide is configured to propagate optical signals having predetermined resonant wavelengths, the electro-optic cladding layer has a voltage-controlled variable refractive index, and the means for applying is configured to apply a wavelength-specific control voltage to the electro-optic cladding layer. The wavelength-specific control voltage will shift or tune the predetermined resonant wavelengths for the ring-shaped waveguide.
FILED Tuesday, September 04, 2007
APPL NO 11/849981
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961990 Krishnamoorthy et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) Oracle America, Inc. (Redwood Shores, California)
INVENTOR(S) Ashok V. Krishnamoorthy (San Diego, California);  James G. Mitchell (Palo Alto, California);  John E. Cunningham (San Diego, California);  Brian W. O'Krafka (Austin, Texas)
ABSTRACT Embodiments of a system are described. This system includes an array of chip modules (CMs) and a baseplate, where the baseplate is configured to communicate data signals via optical communication. Moreover, the array includes first CMs mechanically coupled to first alignment features on the baseplate, and adjacent second CMs mechanically coupled to second alignment features on the baseplate. In this array, a given first CM is electrically coupled to a given set of electrical proximity connectors. Additionally, the array includes bridge components, wherein a given bridge component is electrically coupled to the second SCM and another set of electrical proximity connectors, which is electrically coupled to the set of electrical proximity connectors, thereby facilitating communication of other data signals between adjacent first CMs and second CMs via electrical proximity communication. Moreover, the given bridge component is optically coupled to the baseplate, thereby facilitating optical communication of the data signals between CMs via the baseplate.
FILED Friday, December 21, 2007
APPL NO 11/962419
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961995 Conway et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Josh A. Conway (Redondo Beach, California);  Andrew D. Stapleton (South Pasadena, California)
ABSTRACT An electrically modulated plasmonic junction generates surface plasmons from an electrical signal from an electrical source, with the tunnel junction having a contact with a tapered end forming the junction in a gap between the contact and a substrate, with the gap serving to translate electrical signals into surface plasmons that are in turn translated into emitted photons communicated externally through a transmissive oxide, so that the junction can function as an electrically controlled light emitter preferably built as a nano-scale broadband optical emitter whose output wavelength can be electrically tuned over hundreds of nanometers, can be directly modulated at high speeds, and can have improved efficiencies compared to standard silicon optical sources, and the junction can also operate in a reserve mode for light detection.
FILED Tuesday, September 16, 2008
APPL NO 12/283802
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/39
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962114 Garcia et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Alberto Valdes Garcia (White Plains, New York);  Chinmaya Mishra (College Station, Texas);  Scott Kevin Reynolds (Amawalk, New York)
ABSTRACT A sub-harmonic mixer includes a first transistor having a source and a drain and a second transistor having a source connected to the source of the first transistor and a drain connected to the drain of the first transistor. A mixing transistor is configured to be biased in a linear operating region. The mixing transistor includes a drain coupled to the sources of the first transistor and the second transistor. The mixing transistor has its drain driven by a signal at twice a local oscillator (LO) frequency and its gate driven by a radio frequency (RF) signal while the mixing transistor is biased in the linear region such that a process of frequency doubling and mixing are performed simultaneously.
FILED Friday, January 12, 2007
APPL NO 11/622812
ART UNIT 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Telecommunications
455/323
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962265 Pinney
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Charles P. Pinney (Albuquerque, New Mexico)
ABSTRACT Vehicular sensor systems are provided. The vehicular sensor systems includes a support, first, second, and third sensors, and a support actuator. The first sensor is coupled to the support and configured to rotate about a first sensor axis. The first sensor has a first field of detection with a first central axis. The second sensor is coupled to the support and configured to rotate about a second sensor axis. The second sensor has a second field of detection with a second central axis. The third sensor is coupled to the support and configured to rotate about a third sensor axis. The third sensor has a third field of detection with a third central axis. The support actuator is coupled to the support and configured to rotate the support about a support axis. The first, second, and third central axes are substantially within a plane.
FILED Wednesday, November 28, 2007
APPL NO 11/946385
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/49
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962473 Chen et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Shyh-Kwei Chen (Chappaqua, New York);  Kun-Lung Wu (Yorktown Heights, New York);  Philip Shi-Lung Yu (Chappaqua, New York)
ABSTRACT Techniques are provided for performing structural joins for answering containment queries. Such inventive techniques may be used to perform efficient structural joins of two interval lists which are neither sorted nor pre-indexed. For example, in an illustrative aspect of the invention, a technique for performing structural joins of two element sets of a tree-structured document, wherein one of the two element sets is an ancestor element set and the other of the two element sets is a descendant element set, and further wherein each element is represented as an interval representing a start position and an end position of the element in the document, comprises the following steps/operations. An index is dynamically built for the ancestor element set. Then, one or more structural joins are performed by searching the index with the interval start position of each element in the descendant element set.
FILED Friday, December 28, 2007
APPL NO 11/966537
ART UNIT 2167 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/714
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962700 Franaszek et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Peter Anthony Franaszek (Mount Kisco, New York);  Luis Alfonso Lastras-Montano (Cortlandt Manor, New York);  Robert Brett Tremaine (Stormville, New York)
ABSTRACT Compressed memory systems are provided to reduce latency associated with accessing compressed memory using stratified compressed memory architectures and memory organization protocols in which a region of compressed main memory is allocated as a direct access memory (DAM) region for storing uncompressed data items. The uncompressed data items in the DAM region can be directly accessed, speculatively, to serve access requests to main memory, requiring access to compressed memory in the event of a DAM miss.
FILED Wednesday, September 06, 2006
APPL NO 11/516188
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/153
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962722 Levenstein et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Sheldon B. Levenstein (Austin, Texas);  David S. Levitan (Austin, Texas);  Lixin Zhang (Austin, Texas)
ABSTRACT In at least one embodiment, a processor includes at least one execution unit that executes instructions and instruction sequencing logic, coupled to the at least one execution unit, that fetches instructions from a memory system for execution by the at least one execution unit. The instruction sequencing logic including a branch target address cache (BTAC) including a plurality of entries for storing branch target address predictions. The BTAC includes index logic that selects an entry to access utilizing a BTAC index based upon at least a set of higher order bits of an instruction address and a set of lower order bits of the instruction address.
FILED Friday, February 01, 2008
APPL NO 12/024219
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Processing architectures and instruction processing
712/205
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962798 Locasto et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Michael E. Locasto (Miller, New York);  Angelos D. Keromytis (New York, New York);  Salvatore J. Stolfo (Ridgewood, New Jersey);  Angelos Stavrou (New York, New York);  Gabriela Cretu (New York, New York);  Stylianos Sidiroglou (New York, New York);  Jason Nieh (New York, New York);  Oren Laadan (New York, New York)
ABSTRACT Methods, systems, and media for enabling a software application to recover from a fault condition, and for protecting a software application from a fault condition, are provided. In some embodiments, methods include detecting a fault condition during execution of the software application, restoring execution of the software application to a previous point of execution, the previous point of execution occurring during execution of a first subroutine in the software application, and forcing the first subroutine to forego further execution and return to a caller of the first subroutine.
FILED Tuesday, April 17, 2007
APPL NO 11/785317
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/38.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 07959900 Peng et al.
FUNDED BY
Department of Health and Human Services (HHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) XL Sci-Tech, Inc. (Richland, Washington)
INVENTOR(S) Yongren Benjamin Peng (Richland, Washington);  Xingye Cherry Lei (Richland, Washington)
ABSTRACT Timed-bioresorbable particulates, particularly microspheres or fibers, may be used as a vehicle for delivery of radioisotopes, such as Y-90 and Pd-103 for localized radiotherapy, or as an embolic device. These particulates may also be embedded in polymers, or dispersed in injectable gels or other injectable media for the treatment of various cancers. The benefit of bioresorption, the ability to control the ratio of radioisotopes in the particulate, especially the gamma and beta ratios such as In-111/Y-90 ratio in a particulate, and the benefit of non-conductive implants are disclosed.
FILED Monday, March 07, 2005
APPL NO 10/531996
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959901 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Zhigang He (Wellesley, Massachusetts);  Vuk Koprivica (Bethesda, Maryland)
ABSTRACT Compositions and methods for promoting neural regeneration in a patient determined to have a lesion in a mature CNS neuron are disclosed. The method comprises the step of contacting the neuron with an EGFR inhibitor sufficient to promote regeneration of the neuron.
FILED Wednesday, February 06, 2008
APPL NO 12/026758
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959909 Cox, III
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Bolder BioTechnology, Inc. (Louisville, Colorado)
INVENTOR(S) George N. Cox, III (Louisville, Colorado)
ABSTRACT The growth hormone supergene family comprises greater than 20 structurally related cytokines and growth factors. A general method is provided for creating site-specific, biologically active conjugates of these proteins. The method involves adding cysteine residues to non-essential regions of the proteins or substituting cysteine residues for non-essential amino acids in the proteins using site-directed mutagenesis and then covalently coupling a cysteine-reactive polymer or other type of cysteine-reactive moiety to the proteins via the added cysteine residue. Disclosed herein are preferred sites for adding cysteine residues or introducing cysteine substitutions into the proteins, and the proteins and protein derivatives produced thereby.
FILED Tuesday, October 30, 2007
APPL NO 11/929521
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/85.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959915 Jay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Tufts University (Medford, Massachusetts)
INVENTOR(S) Daniel G. Jay (Brighton, Massachusetts);  Brenda K. Eustace (Brookline, Massachusetts);  Takashi Sakurai (Tokyo, Japan)
ABSTRACT The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells.
FILED Monday, September 12, 2005
APPL NO 11/224726
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959916 Spies et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S) Thomas Spies (Seattle, Washington);  Veronika Groh-Spies (Seattle, Washington)
ABSTRACT The present invention relates to methods of treating immune disorders and cancers. In particular the invention provides methods of inhibiting the negative immunomodulatory effects of ERp-5 on T cells and dendritic cells, in conjunction with other surface receptors.
FILED Wednesday, April 23, 2008
APPL NO 12/108069
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959918 Arditi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Moshe Arditi (Encino, California);  Tripathi Rajavashisth (El Camino Village, California);  Prediman K. Shah (Los Angeles, California)
ABSTRACT Compositions and methods included herein describe the treatment of atherosclerosis and other vascular diseases such as thrombosis, restenosis after angioplasty and/or stenting, and vein-graft disease after bypass surgery, by inhibition of the expression or biologic activity of the toll-like receptor 4 (TLR4) and/or myeloid differentiation factor 88 (MyD88). TLR4 cell signal transduction is at least partially responsible for the manifestation, continuation, and/or worsening of atherosclerosis and other forms of vascular disease. The present invention provides several means with which to inhibit this signal transduction pathway by affecting the biological activity of the TLR4 receptor and/or MyD88.
FILED Wednesday, May 25, 2005
APPL NO 11/569241
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/144.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959925 Weinberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Providence Health System (Seattle, Washington)
INVENTOR(S) Andrew D. Weinberg (Portland, Oregon);  Nicholas P. Morris (Portland, Oregon);  Carmen Romerdaue (Anchorage, Alaska)
ABSTRACT Compositions including a trimeric OX-40 fusion protein are disclosed. Also disclosed are methods for enhancing the immune response of a mammal to an antigen by engaging the OX-40 receptor on the surface of T-cells involving administering to the mammal a composition comprising a trimeric OX-40 fusion protein and a pharmaceutically acceptable carrier.
FILED Friday, November 13, 2009
APPL NO 12/618678
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/192.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959929 Crawford et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  Cornell Research Foundation, Inc. (Ithaca, New York);  The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  Centers for Disease Control and Prevention (Atlanta, Georgia);  Intervet International B.V. (, Netherlands)
INVENTOR(S) Patti C. Crawford (Gainesville, Florida);  Paul J. Gibbs (Gainesville, Florida);  Edward J. Dubovi (Ithaca, New York);  Ruben Omar Donis (Atlanta, Georgia);  Jacqueline Katz (Atlanta, Georgia);  Alexander I. Klimov (Atlanta, Georgia);  Nallakannu P. Lakshmanan (Millsboro, Delaware);  Melissa Anne Lum (Millsboro, Delaware);  Daniel Ghislena Emiel Goovaerts (The Netherlands, Belgium);  Mark William Mellencamp (Desoto, Kansas);  Nancy J. Cox (Atlanta, Georgia);  William L. Castleman (Gainesville, Florida)
ABSTRACT The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.
FILED Thursday, October 19, 2006
APPL NO 11/584818
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/206.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959931 Colegate et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Novartis AG (Basel, Switzerland)
INVENTOR(S) Anthony Colegate (Liverpool, United Kingdom);  Philip Sizer (Liverpool, United Kingdom)
ABSTRACT Antigen and adjuvant components of an adjuvanted influenza vaccine are not mixed during manufacture, but are provided as separate components for extemporaneous mixing at the time of use, for example as a kit comprising (i) an antigen component, comprising an influenza virus antigen; and (ii) an adjuvant component, comprising an aluminium salt.
FILED Monday, November 06, 2006
APPL NO 12/092106
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/209.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959934 Klinman et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland)
INVENTOR(S) Dennis M. Klinman (Potomac, Maryland);  Mayda Gursel (Rockville, Maryland);  Daniela Verthelyi (Potomac, Maryland)
ABSTRACT Novel methods of rapidly generating dendrtic cells are disclosed herein. The methods include contacting a dendritic cell precursor with a D ODN to generate a mature dendritic cell. In one specific, non-limiting example, the method includes contacting the dendritic cell precursor or the mature dendritic cell with an antigen. The methods are of use both in vitro and in vivo.
FILED Friday, March 28, 2008
APPL NO 12/058213
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/278.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959974 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmotte, Illinois);  Yuhuang Wang (Evanston, Illinois);  Daniel Maspoch (L'Escala, Spain)
ABSTRACT Methods and articles providing for precise aligning, positioning, shaping, and linking of nanotubes and carbon nanotubes. An article comprising: a solid surface comprising at least two different surface regions including: a first surface region which comprises an outer boundary and which is adapted for carbon nanotube adsorption, and a second surface region which is adapted for preventing carbon nanotube adsorption, the second region forming an interface with the outer boundary of the first region, at least one carbon nanotube which is at least partially selectively adsorbed at the interface. The shape and size of the patterns on the surface and the length of the carbon nanotube can be controlled to provide for selective interfacial adsorption.
FILED Monday, December 04, 2006
APPL NO 11/633095
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/256
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960104 Drmanac et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Callida Genomics, Inc. (Sunnyvale, California)
INVENTOR(S) Radoje Drmanac (Los Altos Hills, California);  Matthew J. Callow (Redwood City, California);  Brian K. Hauser (Campbell, California);  George Yeung (Mountain View, California)
ABSTRACT The present invention provides methods of making and using self-assembled arrays of single polynucleotide molecules for carrying out a variety of large-scale genetic measurements, such as gene expression analysis, gene copy number assessment, and the like. Random arrays used in the invention are “self-assembled” in the sense that they are formed by deposition of polynucleotide molecules onto a surface where they become fixed at random locations. The polynucleotide molecules fixed on the surface are then identified by direct sequence determination of component nucleic acids, such as incorporated probe sequences, or by other decoding schemes. Such identification converts a random array of determinable polynucleotides, and their respective probes into an addressable array of probe sequences.
FILED Friday, September 29, 2006
APPL NO 11/541225
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960105 Schwartz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) National Institutes of Health (Bethesda, Maryland);  The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  U.S. Government NIH Division of Extramural Inventions and Technology Resources (Washington, District of Columbia)
INVENTOR(S) David C. Schwartz (Madison, Wisconsin);  Kyubong Jo (Champaign, Illinois);  Dalia M. Dhingra (Arlington Heights, Illinois)
ABSTRACT Methods are provided for tagging, characterizing and sorting double-stranded biomolecules while maintaining the integrity of the biomolecules.
FILED Wednesday, November 29, 2006
APPL NO 11/633232
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960110 Bastian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Boris Bastian (Mill Valley, California);  Daniel Pinkel (Lafayette, California)
ABSTRACT This invention provides methods of detecting melanoma. The methods comprises detecting a gain or loss of certain chromosomal regions that undergo copy number changes in melanoma.
FILED Thursday, November 15, 2007
APPL NO 11/941002
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960125 Lewis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) David B. Lewis (Stanford, California);  Christopher Haines (Menlo Park, California);  Thierry Giffon (Mountain View, California);  Xiaowei Lu (Charlottesville, Virginia);  Marc Tessier-Lavigne (South San Francisco, California);  Douglas T. Ross (Huntsville, Alabama)
ABSTRACT The invention provides methods of identifying naïve T cells by expression of PTK7.
FILED Thursday, September 25, 2008
APPL NO 12/238288
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960127 Margolskee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Mount Sinai School of Medicine (New York, New York)
INVENTOR(S) Robert F. Margolskee (Upper Montclair, New Jersey);  Liquan Huang (Havertown, Pennsylvania);  Minqing Rong (Foster City, California);  Marianna Max (Montclair, New Jersey);  Cristian A. Perez (New York, New York)
ABSTRACT The present invention relates to the discovery, identification and characterization of a transient receptor potential channel, referred to herein as TRP8, which is expressed in taste receptor cells and associated with the perception of bitter and sweet taste. The invention encompasses TRP8 nucleotides, host cell expression systems, TRP8 proteins, fusion proteins, polypeptides and peptides, antibodies to the TRP8 protein, transgenic animals that express a TRP8 transgene, and recombinant “knock-out” animals that do not express TRP8. The invention further relates to methods for identifying modulators of the TRP8-mediated taste response and the use of such modulators to either inhibit or promote the perception of bitterness or sweetness. The modulators of TRP8 activity may be used as flavor enhancers in foods, beverages and pharmaceuticals.
FILED Monday, February 25, 2008
APPL NO 12/036860
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960128 Margolskee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Mount Sinai School of Medicine (New York, New York)
INVENTOR(S) Robert F. Margolskee (Upper Montclair, New Jersey);  Liquan Huang (Havertown, Pennsylvania);  Minqing Rong (Foster City, California);  Marianna Max (Montclair, New Jersey);  Cristian A. Perez (New York, New York)
ABSTRACT The present invention relates to the discovery, identification and characterization of a transient receptor potential channel, referred to herein as TRP8, which is expressed in taste receptor cells and associated with the perception of bitter and sweet taste. The invention encompasses TRP8 nucleotides, host cell expression systems, TRP8 proteins, fusion proteins, polypeptides and peptides, antibodies to the TRP8 protein, transgenic animals that express a TRP8 transgene, and recombinant “knock-out” animals that do not express TRP8. The invention further relates to methods for identifying modulators of the TRP8-mediated taste response and the use of such modulators to either inhibit or promote the perception of bitterness or sweetness. The modulators of TRP8 activity may be used as flavor enhancers in foods, beverages and pharmaceuticals.
FILED Friday, March 07, 2008
APPL NO 12/044263
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960129 Penner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Queen's Medical Center (Honolulu, Hawaii)
INVENTOR(S) Reinhold Penner (Honolulu, Hawaii);  Andrea Fleig (Honolulu, Hawaii)
ABSTRACT The present invention provides assays and methods for determining levels of STIM2 activity, thus providing tools for the characterization and study of the regulation of intracellular calcium levels.
FILED Friday, March 21, 2008
APPL NO 12/053329
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960131 Denlinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Loren C. Denlinger (Madison, Wisconsin);  Kirk J. Hogan (Madison, Wisconsin);  Paul J. Bertics (Oregon, Wisconsin);  Kathleen Schell (Madison, Wisconsin)
ABSTRACT A method of assaying nucleotide receptor P2X7 pore activity in white blood cells contained within a mixed cell sample is provided comprising labeling white blood cells with a white blood cell-specific label; depolarizing the labeled white blood cells with an isotonic depolarizing solution; contacting the labeled white blood cells with dye and a P2X7 agonist in an amount sufficient to activate P2X7 pore activity; contacting the labeled white blood cells with a divalent cation in an amount sufficient to deactivate P2X7 pore activity; and analyzing dye uptake whereby P2X7 pore activity is quantified by the amount of dye taken up in labeled white blood cells treated with the P2X7 agonist relative to labeled white blood cells in the absence of said P2X7 agonist, said P2X7 pore activity being corrected for sample age and by subtraction of P2X7 pore activity contributed by nonviable white blood cells.
FILED Tuesday, June 03, 2008
APPL NO 12/132252
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.240
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960139 Sawa et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Academia Sinica (Taipei, Taiwan)
INVENTOR(S) Masaaki Sawa (Ibaraki, Japan);  Chi-Huey Wong (Taipei, Taiwan);  Tsui-Ling Hsu (Taipei, Taiwan);  Sarah Hanson (San Marcos, California)
ABSTRACT The present disclosure relates to a method for metabolic oligosaccharide engineering that incorporates derivatized alkyne-bearing sugar analogs as “tags” into cellular glycoconjugates. The disclosed method incorporates alkynyl derivatized Fuc and alkynyl derivatized ManNAc sugars into a cellular glycoconjugate. A chemical probe comprising an azide group and a visual probe or a fluorogenic probe is used to label the alkyne-derivatized sugar-tagged glycoconjugate. In one aspect, the chemical probe binds covalently to the alkynyl group by Cu(I)-catalyzed [3+2] azide-alkyne cycloaddition and is visualized at the cell surface, intracellularly, or in a cellular extract. The labeled glycoconjugate is capable of detection by flow cytometry, SDS-PAGE, Western blot, ELISA or confocal microscopy, and mass spectrometry.
FILED Monday, March 24, 2008
APPL NO 12/079226
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960147 Danenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Kathleen D Danenberg (Altadena, California);  Peter V Danenberg (Altadena, California);  Steven Swenson (Arcadia, California)
ABSTRACT Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used for quantitative measurement gene expression levels. The tissue sample can be a tumor or other pathological tissue.
FILED Wednesday, July 30, 2003
APPL NO 10/631413
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960159 Barany et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Corneil Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Francis Barany (New York, New York);  Weiguo Cao (Central, South Carolina);  Jianmin Huang (Jackson Heights, New York);  Jing Lu (Tucker, Georgia)
ABSTRACT The present invention is a method for detecting DNA sequence differences including single nucleotide mutations or polymorphisms, one or more nucleotide insertions, and one or more nucleotide deletions. Labeled heteroduplex PCR fragments containing base mismatches are prepared. Endonuclease cleaves the heteroduplex PCR fragments both at the position containing the variation (one or more mismatched bases) and to a lesser extent, at non-variant (perfectly matched) positions. Ligation of the cleavage products with a DNA ligase corrects non-variant cleavages and thus substantially reduces background. This is then followed by a detection step in which the reaction products are detected, and the position of the sequence variations are determined.
FILED Thursday, September 02, 2010
APPL NO 12/874255
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/199
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960163 Dickson et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Georgetown University School of Medicine (Washington, District of Columbia)
INVENTOR(S) Robert B. Dickson (Silver Spring, Maryland);  Chen-Yong Lin (Falls Church, Virginia);  Michael Johnson (Rockville, Maryland);  Shaomeng Wang (Saline, Michigan);  Istvan Enyedy (Hamden, Connecticut)
ABSTRACT The invention is directed to a method of detecting a malignancy or a pre-malignant lesion in breast or other tissue, or a pathologic condition, by detecting the presence of single-chain or two-chain forms of matriptase in the tissue. The invention is further directed to a method of treating malignancies, which have the phenotype of matriptase production by administering a tumor formation inhibiting effective amount of concentrate of Bowman-Birk inhibitor (BBIC), or other matriptase inhibitor. The invention also is directed to nucleic acids encoding a matriptase protein or fragments thereof, and their use for structure elucidation and modeling to identify other inhibitors of matriptase, as well as to methods of identifying matriptase modulating agents, including activators and inhibitors.
FILED Friday, February 29, 2008
APPL NO 12/040467
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/219
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960336 Castillo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) PharmaIN Corporation (Seattle, Washington)
INVENTOR(S) Gerardo M. Castillo (Bothell, Washington);  Elijah M. Bolotin (Bothell, Washington);  Elaine K. Chan (Palo Alto, California)
ABSTRACT The invention describes compositions of peptide analogs exemplified by peptides derived from vasopressin, terlipressin, and GLP1 and others that are active in blood or cleavable in blood to release an active peptide. The peptide analogs have a general formula: A-(Cm)x-Peptide, wherein A is a hydrophobic moiety or a metal binding moiety, and Cm is a cleavable moiety consisting of glycine or alanine or lysine or arginine or N-Arginine or N-lysine, wherein x is an integer between 0-6 and N may be any amino acid or none. A may be linked to Cm by a linker group. The peptide analogs are complexed with polymeric carrier to provide enhanced half-life.
FILED Thursday, July 31, 2008
APPL NO 12/184186
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/1.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960342 Rivier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Salk Institute for Biological Studies (La Jolla, California);  Universitat Bern (Bern, Switzerland);  University Hospital Basel (Basel, Switzerland)
INVENTOR(S) Jean E. F. Rivier (La Jolla, California);  Judit Erchegyi (San Diego, California);  Jean Claude Reubi (Berne, Switzerland);  Helmut R. Maecke (Basel, Switzerland)
ABSTRACT SRIF peptide antagonists, which are selective for SSTR2 in contrast to the other cloned SRIF receptors and which bind with high affinity to the cloned human receptor SSTR2 but do not activate the receptor, have many useful functions. Because they do not bind with significant affinity to SSTR1, SSTR3, SSTR4 or SSTR5, their administration avoids potential undesirable side effects. Because they block the receptor function, they can be used therapeutically to block certain physiological effects which SSTR2 mediates. By incorporating radioiodine or the like in these SSTR2-selective SRIF antagonists, a labeled compound useful in drug-screening methods is provided. Alternatively, for use in therapy, highly radioactive moieties can be N-terminally coupled, complexed or chelated thereto.
FILED Monday, October 15, 2007
APPL NO 11/872367
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/9.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960353 Blagg
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Brian S. J. Blagg (Lawrence, Kansas)
ABSTRACT Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders.
FILED Monday, October 12, 2009
APPL NO 12/577620
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/27
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960356 Klinman et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dennis Klinman (Potomac, Maryland);  Daniela Verthelyi (Potomac, Maryland);  Ken Ishii (Rockville, Maryland);  James J. Mond (Silver Spring, Maryland);  Mayda Gursel (Rockville, Maryland)
ABSTRACT D type CpG oligodeoxynucleotides are provided herein that include a sequence represented by the following formula:
5′ X1X2X3Pu1 Py2 CpG Pu3 Py4 X4X5X6(W)M (G)N-3′
wherein the central CpG motif is unmethylated, Pu is a purine nucleotide, Py is a pyrimidine nucleotide, X and W are any nucleotide, M is any integer from 0 to 10, and N is any integer from 4 to 10. Methods of using these oligodeoxynucleotides to induce an immune response are provided.
FILED Tuesday, May 17, 2005
APPL NO 11/131672
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960361 Debinski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Waldemar Debinski (Winston-Salem, North Carolina);  Neil Christensen (Harrisburg, Pennsylvania);  Akiva Mintz (Brooklyn, New York)
ABSTRACT A method for stimulating a immune response against IL-13Rα2 in a subject having or at risk for developing a disease having cells expressing IL-13Rα2 includes the steps of formulating the anti-cancer vaccine outside of the subject and administering the vaccine to the subject in an amount sufficient to stimulate an immune response against IL-13Rα2 in the subject. A composition for stimulating a immune response against IL-13Rα2 in a subject having or at risk for developing a disease having cells expressing IL-13Rα2 includes an isolated agent that can stimulate immune response against IL-13α2.
FILED Friday, January 25, 2008
APPL NO 12/020391
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960434 Turkson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  University of Central Florida Research Foundation, Inc. (Orlando, Florida);  H. Lee Moffitt Cancer Center and Research Institute (Tampa, Florida)
INVENTOR(S) James Turkson (Orlando, Florida);  Said M. Sebti (Tampa, Florida);  Wayne Guida (Saint Petersburg, Florida);  Man Lun Yip (Monrovia, California);  Nicholas J. Lawrence (Tampa, Florida);  Harshani Lawrence (Tampa, Florida);  Benjamin Greedy (Somerset, United Kingdom)
ABSTRACT The present invention concerns compounds, compositions containing these compounds, and methods of using these compounds and compositions as inhibitors of Stat3 signaling, Stat3 dimerization, Stat3-DNA binding, Stat5-DNA binding, and/or aberrant cell growth in vitro or in vivo, e.g., as anti-cancer agents for treatment of cancer, such as breast cancer. The compounds of the invention include, but are not limited to, NSC 74859 (S3I-201), NSC 42067, NSC 59263, NSC 75912, NSC 11421, NSC 91529, NSC 263435, and pharmaceutically acceptable salts and analogs of the foregoing. Other non-malignant diseases characterized by proliferation of cells that may be treated using the compounds of the invention, but are not limited to, cirrhosis of the liver; graft rejection; restenosis; and disorders characterized by a proliferation of T cells such as autoimmune diseases, e.g., type 1 diabetes, lupus and multiple sclerosis. The invention further includes an in-vitro screening test for the presence of malignant cells in a mammalian tissue; a method of identifying inhibitors of constitutive Stat3 activation, Stat3-DNA binding, Stat5-DNA binding, and/or Stat3 dimerization; and a method of identifying anti-cancer agents.
FILED Monday, May 21, 2007
APPL NO 11/805217
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/518
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960435 Njar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) Vincent C. O. Njar (Glen Burnie, Maryland);  Puranik Purushottamachar (Philadelphia, Pennsylvania)
ABSTRACT A qualitative 3D pharmacophore model (a common feature based model or Catalyst HipHop algorithm) developed from well-known natural product androgen receptor down-regulating agents (ARDAs). The 3D pharmacophore model is used as a template in virtual screening compounds for new ARDAs. ARDA compounds and compounds that strongly inhibit the growth of human prostate LNCaP cells. The compounds may be used in compositions and methods of inhibiting cell proliferation of a cancer and methods of preventing or treating cancer, including prostate cancer.
FILED Friday, December 14, 2007
APPL NO 12/519233
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/604
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960504 Eckert et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Debra M. Eckert (Cambridge, Massachusetts);  David C. Chan (Arcadia, California);  Vladimir Malashkevich (Belmont, Massachusetts);  Peter A. Carr (Somerville, Massachusetts);  Peter S. Kim (Lexington, Massachusetts)
ABSTRACT Inhibitors of HIV membrane fusion and a method of identifying drugs or agents which inhibit binding of the N-helix coiled-coil and the C helix of HIV gp41 envelope protein.
FILED Friday, November 12, 2004
APPL NO 10/987687
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960509 Kaplan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) Trustees of Tufts College (, None);  The United States of America as represented by the Secretary of the Air Force AFMCLO/JAZ (Washington, District of Columbia);  The Board of Trustees of the University of Illinois (, None)
INVENTOR(S) David L. Kaplan (Concord, Massachusetts);  Jia Huang (Medford, Massachusetts);  Cheryl Wong Po Foo (Palo Alto, California);  Rajesh Naik (Dayton, Ohio);  Anne George (Chicago, Illinois)
ABSTRACT The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an organic-inorganic composite. These organic-inorganic composites can be constructed from the nano- to the macro-scale depending on the size of the fibrous protein domain used. The composites can also be loaded with other compounds (e.g. dyes, drugs, enzymes) depending on the goal for the materials, to further enhance function. This can be achieved during assembly of the materials or during the mineralization step in materials formation.
FILED Tuesday, January 17, 2006
APPL NO 11/794934
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960510 Matz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  University of Sydney (Sydney, Australia)
INVENTOR(S) Mikhail Vladimirovitch Matz (Palm Coast, Florida);  Naila Omar Khayyam Alieva (Palm Coast, Florida);  Karen Ann Konzen (St. Augustine, Florida);  Steven Field (Daytona Beach, Florida);  Anya Salih (Waterloo, Australia)
ABSTRACT The subject invention provides new fluorescent and/or colored proteins, and polynucleotide sequences that encode these proteins. The subject invention further provides materials and methods useful for expressing these detectable proteins in biological systems.
FILED Monday, September 29, 2008
APPL NO 12/240241
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960535 Ades et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Edwin W. Ades (Atlanta, Georgia);  George M. Carlone (Stone Mountain, Georgia);  Barun K. De (Snellville, Georgia);  Jacquelyn S. Sampson (College Park, Georgia);  Robert C. Huebner (Stroudsburg, Pennsylvania)
ABSTRACT The present invention relates to recombinant lipidated PsaA proteins and recombinant constructs from which such lipidated PsaA proteins may be expressed. The invention relates further to lipidated PsaA proteins in which lipidation is effected by the use of a heterologous leader sequence derived from the ospA gene of Borrelia burgdorferi, which leader sequence is joined in translational reading frame with the psaA structural gene. The invention also provides methods of preparation of lipidated PsaA proteins and use of such proteins in immunological compositions. Also provided are vaccines comprising immunogenic lipidated PsaA proteins and methods of use of such vaccines in the prevention and treatment of S. pneumoniae infection.
FILED Monday, November 16, 2009
APPL NO 12/619357
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960536 Schwartz et al.
FUNDED BY
Department of Health and Human Services (HHS)
U.S. Public Health Service (USPHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Genetronics, Inc. (San Diego, California)
INVENTOR(S) Robert J. Schwartz (Houston, Texas);  Eric M. Eastman (Highland, Maryland);  Xuyang Li (Houston, Texas);  Jeff Nordstrom (College Station, Texas)
ABSTRACT The invention concerns making and evaluating synthetic regulatory regions for controlling gene expression. The invention features a method for identifying transcription factor binding sites and a method for evaluating the regulatory functions of synthetic regulatory regions.
FILED Monday, March 14, 2005
APPL NO 11/080827
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960548 Pento et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Ohio State University Research Foundation (Columbus, Ohio);  The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) J. Thomas Pento (Norman, Oklahoma);  Pui-Kai Li (Galloway, Ohio);  Robert W. Brueggemeier (Dublin, Ohio);  John C. Hackett (Dublin, Ohio)
ABSTRACT Compounds and methods for treating, inhibiting, or delaying the onset of cancer in a subject by administering a therapeutically effective amount of a keratinocyte growth factor receptor tyrosine kinase (KGFR TK) inhibitor to the subject in need of such treatment. Also provided are compounds and methods for the treating, inhibiting, or delaying the onset of metastasis in a subject with cancer by administering a therapeutically effective amount of a KGFR TK inhibitor to the subject in need of such treatment.
FILED Monday, May 01, 2006
APPL NO 11/414890
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
546/62
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960559 Myers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Andrew G. Myers (Boston, Massachusetts);  Jason D. Brubaker (Cheshire, Connecticut)
ABSTRACT The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides a more efficient route for preparing the enone intermediate.
FILED Friday, July 09, 2010
APPL NO 12/833628
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960588 Lynch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Kevin R. Lynch (Charlottesville, Virginia);  Timothy L. Macdonald (Charlottesville, Virginia)
ABSTRACT Sphingosine-1-phosphate analogs that are potent, and selective agonists at one or more S1P receptors, specifically the S1P1 receptor type are provided. The disclosed compounds include an optional phosphate moiety as well as compounds with hydrolysis-resistant phosphate surrogates such as phosphonates, alpha-substituted phosphonates, and phosphothionates.
FILED Monday, March 29, 2010
APPL NO 12/748981
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
564/443
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960589 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Hao Yang (Waukegan, Illinois);  Lanny S. Liebeskind (Atlanta, Georgia)
ABSTRACT Embodiments of the present disclosure provide for methods of making sphingosines and derivatives thereof, and the like.
FILED Wednesday, September 05, 2007
APPL NO 12/440285
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
564/468
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960606 Raffai et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S)
ASSIGNEE(S) The J. David Gladstone Institutes (Irvine, California);  The Regents of the University of California (Oakland, California);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Robert L. Raffai (Half Moon Bay, California);  Karl Weisgraber (Walnut Creek, California)
ABSTRACT An animal model has been developed where the animals can survive myocardial infarctions caused by diet-induced coronary atherosclerosis, and live with chronic heart failure. This animal model is a result of reduced activity of scavenger receptor class BI (SR-BI) and ApoE and the inducible activity of the Mx1-Cre gene. In a preferred embodiment, the model is a result of crossbreeding two transgenic mouse lines: a knockout of SR-BI (SRBI−/−) and an impaired ApoE expressor (Apoeh/h) to generate a strain referred to as Apoeh/hSRB1−/− mice, which is then crossbred to mice that carry the inducible Mx1-Cre transgene. The Apoeh/hSRB1−/− mouse model is genetically modified, enabling the offspring to rapidly and permanently lower their high blood cholesterol levels caused by dietary challenge. The ability to rapidly and permanently lower blood cholesterol levels in these mice stops and may cause the regression of occlusive coronary atherosclerosis restoring blood flow to the heart, allowing the mice to survive from myocardial infarction and live with chronic heart failure.
FILED Tuesday, June 19, 2007
APPL NO 11/765408
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961187 Borland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) The University of North Carolina (Chapel Hill, North Carolina)
INVENTOR(S) David Borland (Chapel Hill, North Carolina);  John P. Clarke (Chapel Hill, North Carolina);  Russell M. Taylor, II (Pittsboro, North Carolina)
ABSTRACT The invention relates to flexible occlusion rendering, including receiving a first set of three dimensional image data including image data for a surface of interest and image data for a region occluding the surface of interest from a desired viewpoint. The purpose of this invention is to improve occlusion rendering via imaging by locating the occluding surface of the incoming three-dimensional data and, and modifying the characteristics of this data, to show the surface that is being occluded so that the image includes viewing through the occlusion to the surface of interest.
FILED Thursday, March 20, 2008
APPL NO 12/532373
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/424
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961314 Lundquist et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S) Pacific Biosciences of California, Inc. (Menlo Park, California)
INVENTOR(S) Paul Lundquist (San Jose, California);  Denis Zaccarin (San Jose, California);  Yves Lacroix (San Jose, California);  Stephen Turner (Menlo Park, California);  John Dixon (Moss Beach, California)
ABSTRACT Methods and systems for real-time monitoring of optical signals from arrays of signal sources, and particularly optical signal sources that have spectrally different signal components. Systems include signal source arrays in optical communication with optical trains that direct excitation radiation to and emitted signals from such arrays and image the signals onto detector arrays, from which such signals may be subjected to additional processing.
FILED Friday, October 26, 2007
APPL NO 11/978211
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/317
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961922 Spence et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas);  Southern Methodist University (Dallas, Texas)
INVENTOR(S) Jeffrey S. Spence (Forney, Texas);  Patrick S. Carmack (Dallas, Texas);  Qihua Lin (Irving, Texas);  Richard F. Gunst (Dallas, Texas);  William R. Schucany (Dallas, Texas);  Robert W. Haley (Dallas, Texas)
ABSTRACT Systems and methods for processing medical image data with increased sensitivity to facilitate comparisons among groups of subjects are disclosed herein. In one embodiment, a method comprises receiving a first three-dimensional image comprising a plurality of voxels, reducing a regional trend within the three-dimensional image, computing a semivariogram for a region of interest, defining at least one block of spatially correlated voxels, calculating voxel weights for each voxel within the at least one block, and determining a block average count and variance for the at least one block.
FILED Thursday, May 31, 2007
APPL NO 11/756454
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961967 Yoshida et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Hiroyuki Yoshida (Watertown, Massachusetts);  Janne Näppi (Boston, Massachusetts);  Michael E. Zalis (Newtonville, Massachusetts);  Wenli Cai (Dorchester, Massachusetts)
ABSTRACT An adaptive density mapping (ADM) method and system automatically identify interface regions between air and material tagged with contrast agents in computed tomographic (CT) image data, then map CT attenuations of voxels outside the identified interface regions, such that voxels that represent tagged material are made to represent air or another gas.
FILED Thursday, November 30, 2006
APPL NO 11/607195
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/254
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962198 Pogue et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Brian William Pogue (Hanover, New Hampshire);  Daqing Piao (Hanover, New Hampshire)
ABSTRACT An optical tomography system has a group of lasers for generating light of multiple distinct wavelengths within a first wavelength band. Light from these lasers is directed into mammalian tissue at laser-specific locations on the tissue, and light from the mammalian tissue is collected at a plurality of reception points. Collected light from each reception point is separated according to its wavelength, and received by a photodetector to produce path attenuation signals representing attenuation along paths between the laser-specific locations on the tissue and the reception points. Image construction apparatus generates a tomographic image of heme concentrations in the mammalian tissue from the path attenuation signals. In an alternative embodiment, there is a second group of lasers operating in a second wavelength band, and the image construction apparatus can generate an image of heme oxygenation In the mammalian tissue.
FILED Wednesday, April 27, 2005
APPL NO 11/115865
ART UNIT 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Surgery
6/473
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 07958731 McBride et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)
ASSIGNEE(S) SustainX, Inc. (West Lebanon, New Hampshire)
INVENTOR(S) Troy O. McBride (West Lebanon, New Hampshire);  Benjamin R. Bollinger (West Lebanon, New Hampshire);  Michael Izenson (Hanover, New Hampshire);  Weibo Chen (Hanover, New Hampshire);  Patrick Magari (Plainfield, New Hampshire);  Benjamin Cameron (Hanover, New Hampshire)
ABSTRACT The invention relates to systems and methods including an energy conversion system for storage and recovery of energy using compressed gas, a source of recovered thermal energy, and a heat-exchange subsystem in fluid communication with the energy conversion system and the source of recovered thermal energy.
FILED Wednesday, January 20, 2010
APPL NO 12/690513
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/613
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959861 Lopez et al.
FUNDED BY
Department of Defense (DOD)
Defense Intelligence Agency (DIA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Gabriel Lopez (Albuquerque, New Mexico);  Linnea Ista (Albuquerque, New Mexico);  Steven R J Brueck (Albuquerque, New Mexico);  Aurelio Evangelista Lara (Albuquerque, New Mexico);  Mangesh Bore (Albuquerque, New Mexico)
ABSTRACT Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.
FILED Monday, April 14, 2008
APPL NO 12/102663
ART UNIT 3768 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/63
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959873 Roukes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Michael Roukes (Pasadena, California);  Hongxing Tang (Pasadena, California);  Jessica Arlett (S Pasadena, California);  James Maloney (Pasadena, California);  Benjamin Gudlewski (Pasadena, California)
ABSTRACT A biosensor is comprised of a free and a biofunctionalized recognition self-sensing nanocantilever, a dock adjacent to the ends of the nanocantilevers, and a gap between the nanocantilevers and dock. The self-sensing cantilevers each include a semiconductor piezoresistor defined in a pair of legs about which the cantilevers flex. A bias power or current is applied to the piezoresistor. The sensitivity of the cantilevers is optimized for a given ambient temperature and geometry of the cantilevers and dock by minimizing the force spectral density, SF, of the cantilevers to determine the optimum bias power, Pin. A sub-aN/√Hz force sensitivity is obtained by scaling down the dimensions of the cantilevers and supplying an optimum bias power as a function of temperature and geometry.
FILED Thursday, July 20, 2006
APPL NO 11/491394
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959949 Seal et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Sudipta Seal (Oviedo, Florida);  Swanand D. Patil (Orlando, Florida);  Manas K. Haldar (Fargo, North Dakota);  Sanku Mallik (West Fargo, North Dakota)
ABSTRACT The invention provides a composition comprising a plurality of nanoceria particles, a sufficient amount of at least one inhibitor of human carbonic anhydrase II associated with said plurality of nanoceria particles, and a pharmaceutically acceptable carrier containing said plurality of nanoceria particles with associated inhibitor. One preferred inhibitor of human carbonic anhydrase II comprises 4-carboxybenzene sulfonamide. The disclosed composition is useful in treatment of glaucoma.
FILED Friday, June 27, 2008
APPL NO 12/147759
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/489
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959974 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmotte, Illinois);  Yuhuang Wang (Evanston, Illinois);  Daniel Maspoch (L'Escala, Spain)
ABSTRACT Methods and articles providing for precise aligning, positioning, shaping, and linking of nanotubes and carbon nanotubes. An article comprising: a solid surface comprising at least two different surface regions including: a first surface region which comprises an outer boundary and which is adapted for carbon nanotube adsorption, and a second surface region which is adapted for preventing carbon nanotube adsorption, the second region forming an interface with the outer boundary of the first region, at least one carbon nanotube which is at least partially selectively adsorbed at the interface. The shape and size of the patterns on the surface and the length of the carbon nanotube can be controlled to provide for selective interfacial adsorption.
FILED Monday, December 04, 2006
APPL NO 11/633095
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/256
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US 07960105 Schwartz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) National Institutes of Health (Bethesda, Maryland);  The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia);  U.S. Government NIH Division of Extramural Inventions and Technology Resources (Washington, District of Columbia)
INVENTOR(S) David C. Schwartz (Madison, Wisconsin);  Kyubong Jo (Champaign, Illinois);  Dalia M. Dhingra (Arlington Heights, Illinois)
ABSTRACT Methods are provided for tagging, characterizing and sorting double-stranded biomolecules while maintaining the integrity of the biomolecules.
FILED Wednesday, November 29, 2006
APPL NO 11/633232
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960179 Emmett et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Florida State University Research Foundation (Tallahassee, Florida)
INVENTOR(S) Mark R. Emmett (Monticello, Florida);  Sasa Kazazic (Zagreb, Croatia);  Alan G. Marshall (Tallahassee, Florida);  Michael J. Greig (Carlsbad, California)
ABSTRACT Analytical methods using hydrogen/deuterium exchange are provided which reduce or eliminate the back-exchange of deuterium for hydrogen. The methods, which are useful in protein and peptide mapping, include the steps of (a) providing a peptide or protein comprising a solvent accessible hydrogen; (b) exchanging the solvent accessible hydrogen for a deuterium; (c) separating the peptide or protein with supercritical fluid chromatography; and (d) analyzing by mass spectrometry the mass of the separated peptide or protein. Supercritical fluid chromatography enables the observation of fast exchanging hydrogen atoms missed using conventional liquid chromatography methods.
FILED Monday, October 12, 2009
APPL NO 12/577452
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/86
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960218 Ma et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Zhenqiang Ma (Middleton, Wisconsin);  Hao-Chih Yuan (Madison, Wisconsin);  Guogong Wang (Madison, Wisconsin)
ABSTRACT This invention provides methods for fabricating high speed TFTs from silicon-on-insulator and bulk single crystal semiconductor substrates, such as Si(100) and Si(110) substrates. The TFTs may be designed to have a maximum frequency of oscillation of 3 GHz, or better.
FILED Friday, September 08, 2006
APPL NO 11/517812
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/149
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960555 Emrick
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Todd S. Emrick (Deerfield, Massachusetts)
ABSTRACT Versatile Group VIII metathesis catalysts, as can be used in a range of polymerization reactions and other chemical methodologies.
FILED Monday, January 12, 2009
APPL NO 12/319826
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
548/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960559 Myers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Andrew G. Myers (Boston, Massachusetts);  Jason D. Brubaker (Cheshire, Connecticut)
ABSTRACT The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides a more efficient route for preparing the enone intermediate.
FILED Friday, July 09, 2010
APPL NO 12/833628
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960702 Sutko et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Board of Regents of the Nevada System fo Higher Education, on behalf of the University of Nevada, Reno (Reno, Nevada)
INVENTOR(S) John L. Sutko (Reno, Nevada);  Nelson G. Publicover (Reno, Nevada)
ABSTRACT Locations of the origins of the photons are acquired from a scanned sample with reference to a scan frame. The location on the sample from which a photon was emitted is inferred from the location of the scan as commanded by a scan drive signal, a feedback signal related to the position of the scan device, or alternatively by the point in time during a scan at which the photon is detected. A position function, e.g., photon probability density, is associated with a photon position. Summing or other processing of photon probability density functions can require fewer photons to converge to an ideal density distribution associated with an image feature than are required using conventional pixel binning. Stored data can be mapped into pixels or voxels of a display or otherwise processed. Original data remains available in the digital storage for post-hoc analysis. Imprecision introduced by the display process need not adversely affect the precision of the collected data.
FILED Friday, May 20, 2005
APPL NO 11/597028
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/395
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960708 Wolfe et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) University of Houston (Houston, Texas)
INVENTOR(S) John C. Wolfe (Houston, Texas);  Paul Ruchhoeft (Missouri City, Texas)
ABSTRACT Various embodiments disclose devices and methods for fabricating microporous particulate filters with regularly space pores wherein sheet membrane substrates are exposed to energetic particle radiation through a mask and the damaged regions removed in a suitable developer. The required depth of field is achieved by using energetic particles to minimize diffraction and an energetic particle source with suitably small diameter.
FILED Monday, September 17, 2007
APPL NO 11/856615
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/492.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960776 Kim et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Myongseob Kim (Pleasanton, California);  Nick Yu-Min Shen (Hsin-Chu County, Taiwan);  Chungho Lee (Ithaca, New York);  Edwin Chihchuan Kan (Ithaca, New York)
ABSTRACT A sensor includes a field effect transistor having a source, drain, a control gate and floating gate, wherein the floating gate has an extended portion extending away from the control gate. A sensing gate is capacitively coupled to the extended portion of the floating gate. A polymer electret sensing coating is electrically coupled to the sensing gate.
FILED Thursday, September 27, 2007
APPL NO 11/862867
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/314
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961315 Cunningham et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Brian T. Cunningham (Champaign, Illinois);  Nikhil Ganesh (Champaign, Illinois);  Patrick C. Mathias (Orlando, Florida);  Ian D. Block (Champaign, Illinois)
ABSTRACT Enhancement of fluorescence emission from fluorophores bound to a sample and present on the surface of two-dimensional photonic crystals is described. The enhancement of fluorescence is achieved by the combination of high intensity near-fields and strong coherent scattering effects, attributed to leaky photonic crystal eigenmodes (resonance modes). The photonic crystal simultaneously exhibits resonance modes which overlap both the absorption and emission wavelengths of the fluorophore. A significant enhancement in fluorescence intensity from the fluorophores on the photonic crystal surface is demonstrated.
FILED Tuesday, June 15, 2010
APPL NO 12/802890
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/317
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961329 Glazier et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) James A. Glazier (Bloomington, Indiana);  Dragos Amarie (Bloomington, Indiana)
ABSTRACT A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multichannel sensor for detecting the presence of several targets with a single microchip sensor is described. A multichannel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
FILED Wednesday, March 31, 2010
APPL NO 12/751099
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961330 Glazier et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) James A. Glazier (Bloomington, Indiana);  Dragos Amarie (Bloomington, Indiana)
ABSTRACT A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
FILED Wednesday, March 31, 2010
APPL NO 12/751101
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962434 Estan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Cristian Estan (Madison, Wisconsin);  Randy David Smith (Madison, Wisconsin);  Somesh Jha (Madison, Wisconsin)
ABSTRACT Deterministic finite automata (DFAs) are popular solutions to deep packet inspection because they are fast and DFAs corresponding to multiple signatures are combinable into a single DFA. Combining such DFAs causes an explosive increase in memory usage. Extended finite automata (XFAs) are an alternative to DFAs that avoids state-space explosion problems. XFAs extend DFAs with a few bytes of “scratch memory” used to store bits and other data structures that record progress. Simple programs associated with automaton states and/or transitions manipulate this scratch memory. XFAs are deterministic in their operation, are equivalent to DFAs in expressiveness, and require no custom hardware support. Fully functional prototype XFA implementations show that, for most signature sets, XFAs are at least 10,000 times smaller than the DFA matching all signatures. XFAs are 10 times smaller and 5 times faster or 5 times smaller and 20 times faster than systems using multiple DFAs.
FILED Friday, February 15, 2008
APPL NO 12/032380
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/47
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962699 Rajwar et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Ravi Rajwar (Madison, Wisconsin);  James R. Goodman (Madison, Wisconsin)
ABSTRACT One embodiment of the present invention provides a system that facilitates avoiding locks by speculatively executing critical sections of code. During operation, the system allows a process to speculatively execute a critical section of code within a program without first acquiring a lock associated with the critical section. If the process subsequently completes the critical section without encountering an interfering data access from another process, the system commits changes made during the speculative execution, and resumes normal non-speculative execution of the program past the critical section. Otherwise, if an interfering data access from another process is encountered during execution of the critical section, the system discards changes made during the speculative execution, and attempts to re-execute the critical section.
FILED Monday, July 26, 2010
APPL NO 12/843828
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962774 Chakraborty et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madsion, Wisconsin)
INVENTOR(S) Koushik Chakraborty (Madison, Wisconsin);  Philip M. Wells (Madison, Michigan);  Gurindar S. Sohi (Madison, Wisconsin)
ABSTRACT An over-provisioned multicore processor employs more cores than can simultaneously run within the power envelope of the processor, enabling advanced processor control techniques for more efficient workload execution, despite significantly decreasing the duty cycle of the active cores so that on average a full core or more may not be operating.
FILED Thursday, October 04, 2007
APPL NO 11/867508
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Support
713/323
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 07958723 Gonze et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations LLC (, None)
INVENTOR(S) Eugene V. Gonze (Pinckney, Michigan);  Michael J. Paratore, Jr. (Howell, Michigan);  Frank Ament (Troy, Michigan)
ABSTRACT A control system that controls regeneration of a particulate filter is provided. The system generally includes a regeneration module that controls current to the particulate filter to initiate combustion of particulate matter in the particulate filter. A propagation module estimates a propagation status of the combustion of the particulate matter based on a combustion temperature. A temperature adjustment module controls the combustion temperature by selectively increasing a temperature of exhaust that passes through the particulate filter.
FILED Tuesday, May 15, 2007
APPL NO 11/803684
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07958932 Chaudhry et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Fopat LLC (Dayton, Ohio)
INVENTOR(S) Anil R. Chaudhry (Xenia, Ohio);  Robert Dzugan (Cincinnati, Ohio);  Richard M. Harrington (Cincinnati, Ohio);  Faurice D. Neece (Lyndurst, Ohio);  Nipendra P. Singh (Pepper Pike, Ohio)
ABSTRACT A foam material comprises a liquid polymer and a liquid isocyanate which is mixed to make a solution that is poured, injected or otherwise deposited into a corresponding mold. A reaction from the mixture of the liquid polymer and liquid isocyanate inside the mold forms a thermally collapsible foam structure having a shape that corresponds to the inside surface configuration of the mold and a skin that is continuous and unbroken. Once the reaction is complete, the foam pattern is removed from the mold and may be used as a pattern in any number of conventional casting processes.
FILED Thursday, July 03, 2008
APPL NO 12/167546
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal founding
164/516
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959716 Song et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Sun-Ju Song (Orland Park, Illinois);  Tae H. Lee (Naperville, Illinois);  Ling Chen (Woodridge, Illinois);  Stephen E. Dorris (LaGrange Park, Illinois);  Uthamalingam Balachandran (Hinsdale, Illinois)
ABSTRACT A hydrogen permeable membrane is disclosed. The membrane is prepared by forming a mixture of metal oxide powder and ceramic oxide powder and a pore former into an article. The article is dried at elevated temperatures and then sintered in a reducing atmosphere to provide a dense hydrogen permeable portion near the surface of the sintered mixture. The dense hydrogen permeable portion has a higher initial concentration of metal than the remainder of the sintered mixture and is present in the range of from about 20 to about 80 percent by volume of the dense hydrogen permeable portion.
FILED Wednesday, September 30, 2009
APPL NO 12/586978
ART UNIT 1775 — Material and Article Handling
CURRENT CPC
Gas separation: Apparatus
096/11
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US 07959841 Zhao
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Yusheng Zhao (Los Alamos, New Mexico)
ABSTRACT Uniformly dense, diamond-silicon carbide composites having high hardness, high fracture toughness, and high thermal stability are prepared by consolidating a powder mixture of diamond and amorphous silicon. A composite made at 5 GPa/1673K had a measured fracture toughness of 12 MPa·m1/2. By contrast, liquid infiltration of silicon into diamond powder at 5 GPa/1673K produces a composite with higher hardness but lower fracture toughness.
FILED Wednesday, May 31, 2006
APPL NO 11/444649
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/282
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959847 Wicker et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Ryan Wicker (El Paso, Texas);  Francisco Medina (El Paso, Texas);  Christopher Elkins (Redwood City, California)
ABSTRACT Methods and systems of stereolithography for building cost-efficient and time-saving multi-material, multi-functional and multi-colored prototypes, models and devices configured for intermediate washing and curing/drying is disclosed including: laser(s), liquid and/or platform level sensing system(s), controllable optical system(s), moveable platform(s), elevator platform(s), recoating system(s) and at least one polymer retaining receptacle. Multiple polymer retaining receptacles may be arranged in a moveable apparatus, wherein each receptacle is adapted to actively/passively maintain a uniform, desired level of polymer by including a recoating device and a material fill/remove system. The platform is movably accessible to the polymer retaining receptacle(s), elevator mechanism(s) and washing and curing/drying area(s) which may be housed in a shielded enclosure(s). The elevator mechanism is configured to vertically traverse and rotate the platform, thus providing angled building, washing and curing/drying capabilities. A horizontal traversing mechanism may be included to facilitate manufacturing between components of SL cabinet(s) and/or alternative manufacturing technologies.
FILED Thursday, February 19, 2009
APPL NO 12/389147
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/401
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959889 Peng et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Huisheng Peng (Shanghai, China PRC);  Yuntian Theodore Zhu (Cary, North Carolina);  Dean E. Peterson (Los Alamos, New Mexico);  Quanxi Jia (Los Alamos, New Mexico)
ABSTRACT A carbon microtube comprising a hollow, substantially tubular structure having a porous wall, wherein the microtube has a diameter of from about 10 μm to about 150 μm, and a density of less than 20 mg/cm3. Also described is a carbon microtube, having a diameter of at least 10 μm and comprising a hollow, substantially tubular structure having a porous wall, wherein the porous wall comprises a plurality of voids, said voids substantially parallel to the length of the microtube, and defined by an inner surface, an outer surface, and a shared surface separating two adjacent voids.
FILED Wednesday, August 06, 2008
APPL NO 12/221886
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/447.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960037 Liu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Gao Liu (Oakland, California);  Stephen Johnson (Richmond, California);  John B. Kerr (Oakland, California);  Andrew M. Minor (El Cerrito, California);  Samuel S. Mao (Castro Valley, California)
ABSTRACT A thin film device and compound having an anode, a cathode, and at least one light emitting layer between the anode and cathode, the at least one light emitting layer having at least one carbon nanotube and a conductive polymer.
FILED Friday, December 02, 2005
APPL NO 11/293681
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/690
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US 07960141 Ryu et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Youngha Ryu (San Diego, California);  Peter G. Schultz (La Jolla, California)
ABSTRACT The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.
FILED Wednesday, March 07, 2007
APPL NO 11/715672
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960144 Waldo et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Geoffrey S. Waldo (Santa Fe, New Mexico);  Stephanie Cabantous (Los Alamos, New Mexico)
ABSTRACT Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited.
FILED Tuesday, June 24, 2008
APPL NO 12/215053
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960146 Dunn-Coleman et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Danisco US Inc. (Palo Alto, California)
INVENTOR(S) Nigel Dunn-Coleman (Los Gatos, California);  Frits Goedegebuur (Vlaardingen, Netherlands);  Michael Ward (San Francisco, California);  Jian Yao (Sunnyvale, California)
ABSTRACT The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
FILED Friday, August 17, 2007
APPL NO 11/893925
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/72
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960149 Harris et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Paul Harris (Carnation, Washington);  Elizabeth Golightly (Reno, Nevada)
ABSTRACT The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
FILED Wednesday, February 17, 2010
APPL NO 12/707154
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/105
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960534 Thompson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) David N. Thompson (Idaho Falls, Idaho);  William A. Apel (Jackson, Wyoming);  Vicki S. Thompson (Idaho Falls, Idaho);  David W. Reed (Idaho Falls, Idaho);  Jeffrey A. Lacey (Idaho Falls, Idaho)
ABSTRACT Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for transporting sugars across cell membranes using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
FILED Thursday, February 26, 2009
APPL NO 12/380554
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
536/23.700
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US 07960555 Emrick
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Todd S. Emrick (Deerfield, Massachusetts)
ABSTRACT Versatile Group VIII metathesis catalysts, as can be used in a range of polymerization reactions and other chemical methodologies.
FILED Monday, January 12, 2009
APPL NO 12/319826
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
548/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960592 Dumesic et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) James A. Dumesic (Verona, Wisconsin);  Ryan M. West (Madison, Wisconsin)
ABSTRACT A method for converting levulinic acid to methyl vinyl ketone is described. The method includes the steps of reacting an aqueous solution of levulinic acid, over an acid catalyst, at a temperature of from room temperature to about 1100 K. Methyl vinyl ketone is thereby formed.
FILED Tuesday, January 12, 2010
APPL NO 12/685887
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
568/397
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960700 Craig et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) William W. Craig (Pittsburg, California);  Simon E. Labov (Berkeley, California)
ABSTRACT A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.
FILED Friday, September 29, 2006
APPL NO 11/541341
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/370.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960887 Trzynadlowski et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Board of regents of the Nevada System of Higher Education (Reno, Nevada)
INVENTOR(S) Andrzej M. Trzynadlowski (Reno, Nevada);  Ling Qin (Reno, Nevada)
ABSTRACT A permanent-magnet switched-flux (PMSF) device has an outer rotor mounted to a shaft about a central axis extending axially through the PMSF device. First and second pluralities of permanent-magnets (PMs) are respectively mounted in first and second circles, radially outwardly in first and second transverse planes extending from first and second sections of the central axis adjacent to an inner surface of the outer rotor. An inner stator is coupled to the shaft and has i) a stator core having a core axis co-axial with the central axis; and ii) first and second pluralities of stator poles mounted in first and second circles, radially outwardly from the stator core axis in the first and second transverse planes. The first and second pluralities of PMs each include PMs of alternating polarity.
FILED Tuesday, January 12, 2010
APPL NO 12/686264
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/168
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961313 Van Neste et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Charles W. Van Neste (Kingston, Tennessee);  Lawrence R. Senesac (Knoxville, Tennessee);  Thomas G. Thundat (Knoxville, Tennessee)
ABSTRACT A system and method are disclosed for generating a photoacoustic spectrum in an open or closed environment with reduced noise. A source may emit a beam to a target substance coated on a detector that measures acoustic waves generated as a result of a light beam being absorbed by the target substance. By emitting a chopped/pulsed light beam to the target substance on the detector, it may be possible to determine the target's optical absorbance as the wavelength of light is changed. Rejection may decrease the intensity of the acoustic waves on the detector while absorption may increase the intensity. Accordingly, an identifying spectrum of the target may be made with the intensity variation of the detector as a function of illuminating wavelength.
FILED Monday, August 11, 2008
APPL NO 12/189652
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/311
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962150 Hertzog et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Claudia A. Hertzog (Houston, Texas);  Farid U. Dowla (Castro Valley, California);  Gregory E. Dallum (Livermore, California);  Carlos E. Romero (Livermore, California)
ABSTRACT This invention provides a novel high-accuracy indoor ranging device that uses ultra-wideband (UWB) RF pulsing with low-power and low-cost electronics. A unique of the present invention is that it exploits multiple measurements in time and space for very accurate ranging. The wideband radio signals utilized herein are particularly suited to ranging in harsh RF environments because they allow signal reconstruction in spite of multipath propagation distortion. Furthermore, the ranging and positioning techniques discussed herein directly address many of the known technical challenges encountered in UWB localization regarding synchronization and sampling. In the method developed, noisy, corrupted signals can be recovered by repeating range measurements across a channel, and the distance measurements are combined from many locations surrounding the target in a way that minimizes the range biases associated to indirect flight paths and through-wall propagation delays.
FILED Monday, December 11, 2006
APPL NO 11/637388
ART UNIT 2617 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Telecommunications
455/456.100
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 07958733 Turner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Travis L. Turner (Newport News, Virginia);  Roberto J. Cano (Yorktown, Virginia);  Richard J. Silcox (Poquoson, Virginia);  Ralph D. Buehrle (Williamsburg, Virginia);  Christopher M. Cagle (Yorktown, Virginia);  Randolph H. Cabell (Hampton, Virginia);  George C. Hilton (Hampton, Virginia)
ABSTRACT A jet engine exhaust nozzle flow effector is a chevron formed with a radius of curvature with surfaces of the flow effector being defined and opposing one another. At least one shape memory alloy (SMA) member is embedded in the chevron closer to one of the chevron's opposing surfaces and substantially spanning from at least a portion of the chevron's root to the chevron's tip.
FILED Thursday, June 14, 2007
APPL NO 11/762827
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/770
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07959983 Farrar et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Lawrence C. Farrar (Butte, Montana);  Aaron M. Cook (Missoula, Montana);  Scott L. Coguill (Butte, Montana)
ABSTRACT A system and method for applying a material, such as a polymer composition, to a substrate, the method comprising mixing the material with a heated carrier gas stream, spraying the material through a nozzle, and radiant and convective heating of the material during transport. Preferred embodiments of the system and method can be used to spray polyetherimides, polyimides, polyamides, thermoset resins (e.g., and epoxies, polyesters and silicones), liquid crystal polymers, compositions comprising a blowing agent, compositions comprising a binder, compositions comprising a metallized material, compositions that produce an open cell foam, and compositions that produce a closed cell foam.
FILED Wednesday, October 20, 2004
APPL NO 10/970047
ART UNIT 1711 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/422
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961105 Puccio et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Derek Puccio (Cottonwood Heights, Utah);  Donald Malocha (Winter Springs, Florida)
ABSTRACT Weighted surface acoustic wave reflector gratings for coding identification tags and sensors to enable unique sensor operation and identification for a multi-sensor environment. In an embodiment, the weighted reflectors are variable while in another embodiment the reflector gratings are apodized. The weighting technique allows the designer to decrease reflectively and allows for more chips to be implemented in a device and, consequently, more coding diversity. As a result, more tags and sensors can be implemented using a given bandwidth when compared with uniform reflectors. Use of weighted reflector gratings with OFC makes various phase shifting schemes possible, such as in-phase and quadrature implementations of coded waveforms resulting in reduced device size and increased coding.
FILED Friday, May 14, 2010
APPL NO 12/780321
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/572.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961329 Glazier et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) James A. Glazier (Bloomington, Indiana);  Dragos Amarie (Bloomington, Indiana)
ABSTRACT A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multichannel sensor for detecting the presence of several targets with a single microchip sensor is described. A multichannel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
FILED Wednesday, March 31, 2010
APPL NO 12/751099
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07961330 Glazier et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)
ASSIGNEE(S) Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S) James A. Glazier (Bloomington, Indiana);  Dragos Amarie (Bloomington, Indiana)
ABSTRACT A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
FILED Wednesday, March 31, 2010
APPL NO 12/751101
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/445
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962252 Shams et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Qamar A. Shams (Yorktown, Virginia);  Michael J. Logan (Chesapeake, Virginia);  Robert L. Fox (Hayes, Virginia);  Christopher L. Fox, legal representative (Yorktown, Virginia);  Melanie L. Fox, legal representative (Hayes, Virginia);  John C. Ingham (Alexandria, Virginia);  Sean A. Laughter (Chester, Virginia);  Theodore R. Kuhn, III (Fredericksburg, Virginia);  James K. Adams (Gloucester, Virginia);  Walter C. Babel, III (Smithfield, Virginia)
ABSTRACT A self-contained avionics sensing and flight control system is provided for an unmanned aerial vehicle (UAV). The system includes sensors for sensing flight control parameters and surveillance parameters, and a Global Positioning System (GPS) receiver. Flight control parameters and location signals are processed to generate flight control signals. A Field Programmable Gate Array (FPGA) is configured to provide a look-up table storing sets of values with each set being associated with a servo mechanism mounted on the UAV and with each value in each set indicating a unique duty cycle for the servo mechanism associated therewith. Each value in each set is further indexed to a bit position indicative of a unique percentage of a maximum duty cycle for the servo mechanism associated therewith. The FPGA is further configured to provide a plurality of pulse width modulation (PWM) generators coupled to the look-up table. Each PWM generator is associated with and adapted to be coupled to one of the servo mechanisms.
FILED Thursday, June 08, 2006
APPL NO 11/422984
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/3
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 07959900 Peng et al.
FUNDED BY
Department of Health and Human Services (HHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) XL Sci-Tech, Inc. (Richland, Washington)
INVENTOR(S) Yongren Benjamin Peng (Richland, Washington);  Xingye Cherry Lei (Richland, Washington)
ABSTRACT Timed-bioresorbable particulates, particularly microspheres or fibers, may be used as a vehicle for delivery of radioisotopes, such as Y-90 and Pd-103 for localized radiotherapy, or as an embolic device. These particulates may also be embedded in polymers, or dispersed in injectable gels or other injectable media for the treatment of various cancers. The benefit of bioresorption, the ability to control the ratio of radioisotopes in the particulate, especially the gamma and beta ratios such as In-111/Y-90 ratio in a particulate, and the benefit of non-conductive implants are disclosed.
FILED Monday, March 07, 2005
APPL NO 10/531996
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960180 Chang et al.
FUNDED BY
Environmental Protection Agency (EPA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) University of Notre Dame Du Lac (Notre Dame, Indiana);  Scientific Methods, Inc. (Granger, Indiana)
INVENTOR(S) Hsueh-Chia Chang (Granger, Indiana);  Zilin Chen (Wuhan, China PRC);  Fu-Chih Hsu (Granger, Indiana);  David Battigelli (Granger, Indiana)
ABSTRACT Methods and apparatus to capture and release microbe particles using amino-functionalized silica substrates are described. An example apparatus adapted to capture a microbe particle includes a silica substrate and a positively charged material to at least partially coat the silica substrate. The positive charged material includes an aminopropyl functional group.
FILED Tuesday, February 19, 2008
APPL NO 12/033705
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/161
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960536 Schwartz et al.
FUNDED BY
Department of Health and Human Services (HHS)
U.S. Public Health Service (USPHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Genetronics, Inc. (San Diego, California)
INVENTOR(S) Robert J. Schwartz (Houston, Texas);  Eric M. Eastman (Highland, Maryland);  Xuyang Li (Houston, Texas);  Jeff Nordstrom (College Station, Texas)
ABSTRACT The invention concerns making and evaluating synthetic regulatory regions for controlling gene expression. The invention features a method for identifying transcription factor binding sites and a method for evaluating the regulatory functions of synthetic regulatory regions.
FILED Monday, March 14, 2005
APPL NO 11/080827
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 07960461 Lin
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Samuel Q. Lin (Newark, New Jersey)
ABSTRACT The invention is an article of manufacture, comprising a blend of: (A) from 1 to 50 weight percent of at least one block copolymer, wherein the block copolymer has at least one polystyrene block and at least one unsaturated rubber segment; and (B) from 99 to 50 weight percent of a natural oil. The natural oil of this invention is of natural animal, plant or vegetable oils or mixtures thereof, and the block copolymers have a polystyrene block and a rubber block where the rubber blocks are unsaturated rubbers such as polyisoprene, polybutadiene, or mixtures thereof. The block copolymers useful for the present invention are triblock polymers, radial (star) polymers, multiblock polymers, diblock polymers, or mixtures thereof.
FILED Wednesday, October 21, 2009
APPL NO 12/589358
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
524/318
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07960574 Dickey et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Leland C. Dickey (Blue Bell, Pennsylvania);  Michael F. Dallmer (Philadelphia, Pennsylvania)
ABSTRACT Methods of separating oil from oil-containing seeds, involving aerating an aqueous dispersion of germ particles of oil-containing seeds (e.g., corn) to produce bubbles therein, whereby the oil in the aqueous dispersion adheres preferentially to the surfaces of the bubbles and are carried by the bubbles to the upper surface of the aqueous dispersion where a foam of the bubbles is formed; separating the foam from the aqueous dispersion; and recovering the oil from the foam. The aqueous dispersion of germ particles of oil-containing seeds may be produced by mixing corn germ separated from corn kernels with an aqueous acetate buffer followed by heating, grinding, cooling, and optionally agitation; generally cellulase is added after the grinding.
FILED Wednesday, December 19, 2007
APPL NO 12/002934
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
554/11
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 07961631 Chen et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Shyh-Kwei Chen (Chappaqua, New York);  Michail Vlachos (Tarrytown, New York);  Kun-Lung Wu (Yorktown Heights, New York);  Philip Shi-lung Yu (Chappaqua, New York)
ABSTRACT Systems and methods for the identification of correlated burst events among two or more data streams, given one or more specific query time spans are disclosed. Also broadly contemplated is the act of finding, from one or more data streams, those streams that have correlated burst events with another given data stream within a time span.
FILED Tuesday, July 22, 2008
APPL NO 12/177379
ART UNIT 2462 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 07962473 Chen et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Shyh-Kwei Chen (Chappaqua, New York);  Kun-Lung Wu (Yorktown Heights, New York);  Philip Shi-Lung Yu (Chappaqua, New York)
ABSTRACT Techniques are provided for performing structural joins for answering containment queries. Such inventive techniques may be used to perform efficient structural joins of two interval lists which are neither sorted nor pre-indexed. For example, in an illustrative aspect of the invention, a technique for performing structural joins of two element sets of a tree-structured document, wherein one of the two element sets is an ancestor element set and the other of the two element sets is a descendant element set, and further wherein each element is represented as an interval representing a start position and an end position of the element in the document, comprises the following steps/operations. An index is dynamically built for the ancestor element set. Then, one or more structural joins are performed by searching the index with the interval start position of each element in the descendant element set.
FILED Friday, December 28, 2007
APPL NO 11/966537
ART UNIT 2167 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/714
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 07962798 Locasto et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Michael E. Locasto (Miller, New York);  Angelos D. Keromytis (New York, New York);  Salvatore J. Stolfo (Ridgewood, New Jersey);  Angelos Stavrou (New York, New York);  Gabriela Cretu (New York, New York);  Stylianos Sidiroglou (New York, New York);  Jason Nieh (New York, New York);  Oren Laadan (New York, New York)
ABSTRACT Methods, systems, and media for enabling a software application to recover from a fault condition, and for protecting a software application from a fault condition, are provided. In some embodiments, methods include detecting a fault condition during execution of the software application, restoring execution of the software application to a previous point of execution, the previous point of execution occurring during execution of a first subroutine in the software application, and forcing the first subroutine to forego further execution and return to a caller of the first subroutine.
FILED Tuesday, April 17, 2007
APPL NO 11/785317
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/38.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 07960606 Raffai et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S)
ASSIGNEE(S) The J. David Gladstone Institutes (Irvine, California);  The Regents of the University of California (Oakland, California);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Robert L. Raffai (Half Moon Bay, California);  Karl Weisgraber (Walnut Creek, California)
ABSTRACT An animal model has been developed where the animals can survive myocardial infarctions caused by diet-induced coronary atherosclerosis, and live with chronic heart failure. This animal model is a result of reduced activity of scavenger receptor class BI (SR-BI) and ApoE and the inducible activity of the Mx1-Cre gene. In a preferred embodiment, the model is a result of crossbreeding two transgenic mouse lines: a knockout of SR-BI (SRBI−/−) and an impaired ApoE expressor (Apoeh/h) to generate a strain referred to as Apoeh/hSRB1−/− mice, which is then crossbred to mice that carry the inducible Mx1-Cre transgene. The Apoeh/hSRB1−/− mouse model is genetically modified, enabling the offspring to rapidly and permanently lower their high blood cholesterol levels caused by dietary challenge. The ability to rapidly and permanently lower blood cholesterol levels in these mice stops and may cause the regression of occlusive coronary atherosclerosis restoring blood flow to the heart, allowing the mice to survive from myocardial infarction and live with chronic heart failure.
FILED Tuesday, June 19, 2007
APPL NO 11/765408
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/9
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 07960180 Chang et al.
FUNDED BY
Environmental Protection Agency (EPA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) University of Notre Dame Du Lac (Notre Dame, Indiana);  Scientific Methods, Inc. (Granger, Indiana)
INVENTOR(S) Hsueh-Chia Chang (Granger, Indiana);  Zilin Chen (Wuhan, China PRC);  Fu-Chih Hsu (Granger, Indiana);  David Battigelli (Granger, Indiana)
ABSTRACT Methods and apparatus to capture and release microbe particles using amino-functionalized silica substrates are described. An example apparatus adapted to capture a microbe particle includes a silica substrate and a positively charged material to at least partially coat the silica substrate. The positive charged material includes an aminopropyl functional group.
FILED Tuesday, February 19, 2008
APPL NO 12/033705
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/161
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 07962421 Gullo et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) John F. Gullo (Alexandria, Virginia);  James D. Wilson (Collierville, Tennessee);  Robert F. Snapp (Memphis, Tennessee);  David J. Payne (Collierville, Tennessee)
ABSTRACT This invention provides methods, apparatus, and systems for classifying addresses. An address is evaluated based upon a postal code or standardized postal code, such as a U.S. Postal Service ZIP+4 code, serving the address. If the address cannot be classified based on the standardized postal code, the address is classified based on additional information, such as a U.S. Postal Service delivery point code. A mailer may then determine whether the address is a business or residential (or non-business) address. Furthermore, a mailer may predict when surcharges may apply and compare the rates of various carriers.
FILED Monday, March 25, 2002
APPL NO 10/311466
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/338
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 07960166 Vacanti et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  The Charles Stark Draper Laboratory (Cambridge, Massachusetts)
INVENTOR(S) Joseph P. Vacanti (Boston, Massachusetts);  Jeffrey T. Borenstein (Holliston, Massachusetts);  Eli Weinberg (Needham, Massachusetts)
ABSTRACT The present invention relates to a three-dimensional system, and compositions obtained therefrom, wherein individual layers of the system comprise channels divided longitudinally into two compartments by a centrally positioned membrane, and wherein each compartment can comprise a different cell type.
FILED Friday, May 21, 2004
APPL NO 10/557081
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/284.100
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 14, 2011.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2011/fedinvent-patents-20110614.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital