FedInvent™ Patents
Patent Details for Tuesday, July 19, 2011
This page was updated on Monday, March 27, 2023 at 02:02 AM GMT
Department of Health and Human Services (HHS)
US 07980149 | Godfrey et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Inverness Medical Switzerland GmbH (Zug, Switzerland) |
INVENTOR(S) | Daniel Peterson Godfrey (Cambridge, United Kingdom); Mark John Frogley (Huntington, United Kingdom); Christopher Durham Whalen (Pleasant Prairie, Wisconsin) |
ABSTRACT | A docking mechanism provided for analytical apparatus, such as an acoustic bio-sensor apparatus. The mechanism is operable releasably to receive a cartridge (58) for use in analysing a sample comprising a fluid and having a flow cell (104, 106; 304, 306) for the sample and an electrically operated sensor (92) for performing the analysis. The docking mechanism has a clamping mechanism (12, 8, 10) for urging a fluid connector such as ferules (50, 52) against the cartridge to provide a fluid connection between the flow cell inlet and a sample delivery device. The docking mechanism also has an electrical connector (74, 76, 78) for engaging the sensor to connect the latter to electrical circuitry for operating the sensor, the electrical connector being moveable towards and away from the sensor relative to the clamping mechanism, so that, in use, the electrical connector exerts on the sensor a force which is sufficient to maintain the necessary electrical connection, while not being so great as to have a substantial detrimental effect on the accuracy of the sensor. There is also shown analytical apparatus which includes such a docking mechanism. |
FILED | Friday, March 31, 2006 |
APPL NO | 11/817853 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/864.850 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981058 | Akay |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
INVENTOR(S) | Metin Akay (Hanover, New Hampshire) |
ABSTRACT | An intelligent wearable monitoring system includes a wireless personal area network for extended monitoring of a patient's motor functions. The wireless personal area network includes an intelligent accelerometer unit, a personal server and a remote access unit. The intelligent accelerometer unit measures acceleration data of the patient, in real-time. The personal server processes the acceleration data, applying linear and non-linear analysis, such as fractal analysis, to generate motor function information from the acceleration data. Motor function information is transmitted to a remote access unit for statistical analysis and formatting into visual representations. A data management unit receives the formatted motor function information and displays the information, for example, for viewing by the patient's physician. |
FILED | Monday, March 14, 2005 |
APPL NO | 11/079496 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/595 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981122 | Labadie et al. |
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ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Robert F. Labadie (Nashville, Tennessee); J. Michael Fitzpatrick (Nashville, Tennessee); Jason E. Mitchell (Nashville, Tennessee) |
ABSTRACT | In one aspect, the present invention relates to a surgical instrument for providing an access to a target of interest of a living subject. In one embodiment, the surgical instrument has a bearing member, a shaft member and a probe. The bearing member has a first end portion, an opposite, second end portion, a body portion defined therebetween having a longitudinal axis, and a shoulder portion extending from the second end portion. The body portion defines a bore therein along the longitudinal axis. The shoulder portion defines a passage substantially coaxial with and in communication with the bore. The shaft member has an first end portion and an opposite, second end portion, and is slidably received in the bore of the bearing member. The shaft member defines a space extending from the first end portion to the second end portion. The probe has a working end portion and is received in the space of the shaft member such that the working end portion is extendable through the passage of the shoulder portion of the bearing member to reach a target of interest of a living subject so as to provide an access thereto. |
FILED | Tuesday, July 24, 2007 |
APPL NO | 11/782305 |
ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 66/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981417 | Shusta et al. |
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ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Eric V. Shusta (Madison, Wisconsin); Xin Xiang Wang (Gaithersburg, Maryland); Yongku Peter Cho (Madison, Wisconsin) |
ABSTRACT | This invention provides antibodies that bind brain endothelial cell receptors resulting in endocytosis/transcytosis of the receptor and bound ligands. In some embodiments, the ligand comprises the antibody in combination with a pharmaceutically active compound and the antibody directs delivery of the compound across the blood brain barrier (BBB). The invention also provides methods of identifying endothelial cell specific antibodies by panning the library against cultured cell monolayers. The invention further allows for identifying endothelial cell receptors that bind the antibody thereby providing target receptors against which to isolate further cognate ligands and their associated transport systems and by which to identify transcytosis transporters targeted by the antibodies. |
FILED | Monday, August 03, 2009 |
APPL NO | 12/540897 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/134.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981421 | Zhou et al. |
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ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
INVENTOR(S) | Tong Zhou (Birmingham, Alabama); Kimihisa Ichikawa (Kanagawa-ken, Japan); Robert P. Kimberly (Birmingham, Alabama); William J. Koopman (Indian Springs, Alabama); Jun Ohsumi (Kanagawa-ken, Japan); Albert F. LoBuglio (Birmingham, Alabama); Donald J. Buchsbaum (Alabaster, Alabama) |
ABSTRACT | An antibody of the invention interacts with human DR5 or with human DR4 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Methods and uses for the antibodies, optionally in combination with various therapeutic agents, are detailed, including treatment of apoptosis-related disease and treatment of dysregulated cell growth. |
FILED | Wednesday, January 13, 2010 |
APPL NO | 12/686659 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/143.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981448 | Otterbein et al. |
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ASSIGNEE(S) | University of Pittsburgh (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Leo E. Otterbein (New Kensington, Pennsylvania); Brian Zuckerbraun (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to a method of treating necrotizing enterocolitis in a patient, which includes administering a pharmaceutical composition that includes carbon monoxide to the patient. |
FILED | Tuesday, April 15, 2003 |
APPL NO | 10/413817 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/699 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981603 | Feinberg |
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ASSIGNEE(S) | The Johns Hopkins University School of Medicine (Baltimore, Maryland) |
INVENTOR(S) | Andrew P. Feinberg (Lutherville, Maryland) |
ABSTRACT | The present invention provides methods and kits for identifying an increased risk of developing cancer in a subject. The methods include analyzing a first biological sample, such as a blood sample, from the subject for loss of imprinting of the IGF2 gene. According to the methods a loss of imprinting is indicative of an increased risk of developing cancer. The method can include analyzing genomic DNA from the sample for altered methylation of the IGF2 or the H19 gene. The altered methylation for example includes hypomethylation of a differentially methylated region of IGF2, corresponding to SEQ ID NO:1 and/or a polymorphism or fragment thereof, or hypomethylation of a differentially methylated region of H19 corresponding to SEQ ID NO:6, or a polymorphism, or fragment thereof. In certain aspects, hypomethylation of the H19 DMR or the IGF2 DMR indicates an increased risk of developing colorectal cancer. |
FILED | Monday, July 28, 2003 |
APPL NO | 10/629318 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981609 | Rubin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Mark A. Rubin (Cambridge, Massachusetts); Francesca Demichelis (Cambridge, Massachusetts); Levi A. Garraway (Newton, Massachusetts); William R. Sellers (Brookline, Massachusetts) |
ABSTRACT | Described are methods for identifying single nucleotide polymorphism (SNPs) that are useful for analyzing genetic samples, and for using said SNPs to determine genetic identity of samples. |
FILED | Friday, June 08, 2007 |
APPL NO | 11/811149 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981610 | Staudt et al. |
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ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Louis M. Staudt (Silver Spring, Maryland); Andreas Rosenwald (Bethesda, Maryland); Wyndham Wilson (Washington, District of Columbia); Todd S. Barry (Seattle, Washington); Adrian Wiestner (Bethesda, Maryland) |
ABSTRACT | It has been surprisingly found that ZAP-70 expression, both at the protein and mRNA levels, is indicative of clinical subgroups of CLL/SLL patients. In particular, high ZAP-70 expression is indicative of Ig-unmutated CLL/SLL. Methods are provided for discriminating between clinical subgroups of CLL/SLL, by determining whether subjects overexpress ZAP-70 mRNA or protein. |
FILED | Wednesday, December 12, 2007 |
APPL NO | 11/955322 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981612 | Shuber et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Exact Sciences Corporation (Marlborough, Massachusetts) |
INVENTOR(S) | Anthony P. Shuber (Mendon, Massachusetts); David A. Alquist (Rochester, Minnesota) |
ABSTRACT | The invention provides methods and materials for detecting supracolonic aerodigestive premalignant and malignant neoplasms. Specifically, the invention provides methods and materials for determining whether a stool sample from a mammal contains a neoplasm-specific marker from a neoplasm located in the supracolonic aerodigestive tissue of a mammal. |
FILED | Wednesday, March 05, 2008 |
APPL NO | 12/042988 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981615 | Evans et al. |
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ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Sylvia Evans (Del Mar, California); Ju Chen (San Diego, California); Chenleng Cai (San Diego, California); Wenlai Zhou (San Diego, California); Michael G. Rosenfeld (San Diego, California) |
ABSTRACT | The invention herein provides a mode of treating a disease associated with the regulation of T-Box and N-Myc gene, which includes cancers and heart disease in human and other subjects by identifying and administering a compound which modulates T-Box or N-Myc function. The invention also provides polynucleotides, polypeptides, vectors, cells, tissues and organisms useful in the identification and treatment of metabolic syndrome. A number of desirable cell proliferation and senescence regulating aspects are achieved by various embodiments of the present invention. |
FILED | Monday, November 02, 2009 |
APPL NO | 12/611047 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981625 | Wang et al. |
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ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Denong Wang (Palo Alto, California); Leonore A. Herzenberg (Stanford, California); Donna M. Peehl (Mountain View, California); Leonard A. Herzenberg (Palo Alto, California) |
ABSTRACT | Disclosed are methods for probing the immunogenic sugar moieties of prostate cancer cells. The methods detect a number of glyco-epitopes that are highly and differentially expressed among prostate cancers of various Gleason grades. The glyco-epitopes exist on the surfaces of prostate cells. The methods also comprise the detection of autoantibodies in prostate cancer subjects. The antibodies bound to a glyco-motif of N-glycans that is normally “cryptic.” This target is highly expressed in prostate cancers. Lectins and antibodies that detect these glyco-epitopes that expressed in prostate cancer tissues include Euonymus europaeus lectin (EEL); Psophocarpus Tetragonolobus Lectin-I (PTL-I); Griffonia Simplicifolia Lectin-I-A4 (GSL-I-A4); Griffonia Simplicifolia Lectin-I-B4 (GSL-I-B4); Sambucus nigra I agglutinin (SNA-I; Phaseolus vulgaris-L (PHA-L; Galanthus nivalis agglutinin (GNA); Narcissus pseudonarcissus agglutinin (NPA); Artocarpus integrifolia agglutinin (Jacalin); and mAb TM10 (IgM). |
FILED | Friday, April 10, 2009 |
APPL NO | 12/421964 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981628 | Grompe et al. |
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ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Markus Grompe (Portland, Oregon); Philip R. Streeter (Portland, Oregon); Craig Dorrell (Portland, Oregon); Stephanie L. Abraham (Clancy, Montana); Kelsea Shoop (Oregon City, Oregon) |
ABSTRACT | Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof. Isolated monoclonal antibodies are also disclosed herein that specifically bind a cell surface antigen expressed on human pancreatic exocrine cells or human ductal cells. Humanized forms of these antibodies, and functional fragments of these antibodies, are also disclosed. The antibodies can be conjugated to an effector molecule, such as a detectable marker, a therapeutic agent, or a toxin. These antibodies are of use to detect and isolate pancreatic cells or a subset thereof. The antibodies can be used for in vitro or in vivo detection and/or isolation of pancreatic endocrine cells. Methods of treating a pancreatic tumor are also disclosed. In several examples, the isolated monoclonal antibodies bind pancreatic endocrine cells and can be used to detect diabetes or a pancreatic endocrine cell tumor. |
FILED | Friday, April 27, 2007 |
APPL NO | 12/298761 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981631 | Handfield et al. |
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ASSIGNEE(S) | University of Florida Research Foundation (Gainesville, Florida) |
INVENTOR(S) | Martin Handfield (Gainesville, Florida); Jeffrey Daniel Hillman (Gainesville, Florida); Ann Progulske-Fox (Keystone Heights, Florida) |
ABSTRACT | Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans. |
FILED | Monday, November 22, 2010 |
APPL NO | 12/951484 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981655 | Harris et al. |
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ASSIGNEE(S) | Regents of the University of Minnesota (Saint Paul, Minnesota) |
INVENTOR(S) | Reuben S Harris (St. Paul, Minnesota); Hiroshi Matsuo (St. Paul, Minnesota) |
ABSTRACT | The document provides modified cytosine deaminases with increased solubility and high levels of DNA cytosine deaminase activity. |
FILED | Friday, February 06, 2009 |
APPL NO | 12/322868 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/227 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981656 | Sanders et al. |
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ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); Centers for Disease Control and Prevention (Atlanta, Georgia) |
INVENTOR(S) | David A. Sanders (West Lafayette, Indiana); Scott A. Jeffers (Aurora, Colorado); Anthony Sanchez (Lilburn, Georgia) |
ABSTRACT | Pseudotyped retroviruses having viral glycoproteins with modified O glycosylation regions are provided. Also provided are methods for making the pseudotyped retroviruses of the present invention and for using the pseudotyped retroviruses for transduction of target cells. Cells for stably producing the pseudotyped retroviruses or the present invention are also provided. |
FILED | Wednesday, June 04, 2003 |
APPL NO | 10/516578 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981660 | Gerngross |
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ASSIGNEE(S) | Glycofi, Inc. (Lebanon, New Hampshire) |
INVENTOR(S) | Tillman U. Gerngross (Hanover, New Hampshire) |
ABSTRACT | Cell lines having genetically modified glycosylation pathways that allow them to carry out a sequence of enzymatic reactions, which mimic the processing of glycoproteins in humans, have been developed. Recombinant proteins expressed in these engineered hosts yield glycoproteins more similar, if not substantially identical, to their human counterparts. The lower eukaryotes, which ordinarily produce high-mannose containing N-glycans, including unicellular and multicellular fungi are modified to produce N-glycans such as Man5GlcNAc2 or other structures along human glycosylation pathways. This is achieved using a combination of engineering and/or selection of strains which: do not express certain enzymes which create the undesirable complex structures characteristic of the fungal glycoproteins, which express exogenous enzymes selected either to have optimal activity under the conditions present in the fungi where activity is desired, or which are targeted to an organelle where optimal activity is achieved, and combinations thereof wherein the genetically engineered eukaryote expresses multiple exogenous enzymes required to produce “human-like” glycoproteins. |
FILED | Thursday, August 27, 2009 |
APPL NO | 12/549062 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/254.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981667 | Nie et al. |
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ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
INVENTOR(S) | Shuming Nie (Atlanta, Georgia); Robert E. Bailey (Sacramento, California) |
ABSTRACT | An alloyed semiconductor quantum dot comprising an alloy of at least two semiconductors, wherein the quantum dot has a homogeneous composition and is characterized by a band gap energy that is non-linearly related to the molar ratio of the at least two semiconductors; a series of alloyed semiconductor quantum dots related thereto; a concentration-gradient quantum dot comprising an alloy of a first semiconductor and a second semiconductor, wherein the concentration of the first semiconductor gradually increases from the core of the quantum dot to the surface of the quantum dot and the concentration of the second semiconductor gradually decreases from the core of the quantum dot to the surface of the quantum dot; a series of concentration-gradient quantum dots related thereto; in vitro and in vivo methods of use; and methods of producing the alloyed semiconductor and concentration-gradient quantum dots and the series of quantum dots related thereto. |
FILED | Wednesday, April 28, 2004 |
APPL NO | 10/555729 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/288.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981688 | Stayton et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Patrick S. Stayton (Seattle, Washington); Allan S. Hoffman (Seattle, Washington); Jr-iuan Lai (Seattle, Washington); John Hoffman (Seattle, Washington); Mitsuhiro Ebara (Mino, Japan) |
ABSTRACT | Stimuli-responsive magnetic nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles. |
FILED | Thursday, March 08, 2007 |
APPL NO | 11/683889 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/149 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981694 | Boss et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Gerry R. Boss (La Jolla, California); Stephen B. Jones (San Diego, California); Jeffrey C. Chen (San Gabriel, California); Friederike von Lintig (San Diego, California); Stephanie Hoffman (Patatuma, California); Adam Kimmerly (San Diego, California); Joann Luu (San Jose, California); Matthew Christopher Mycroft (Sierra Madre, California) |
ABSTRACT | The invention is a method for the isolation of molecules of interest using tubes in which at least a portion of the inner walls of the tube are coated with microbeads that are coated with a capture reagent to bind the molecule of interest. The microbeads may be glass or polymer beads. The invention is a method and apparatus for preparation of the tubes for use in the method of the invention. The invention is a method for determining ratios of guanine nucleotides bound to guanine-nucleotide binding proteins. |
FILED | Wednesday, January 28, 2004 |
APPL NO | 10/767251 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/518 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981866 | Ma et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey) |
INVENTOR(S) | Jianjie Ma (Belle Mead, New Jersey); Noah Weisleder (Elizabeth, New Jersey); Chuanxi Cai (Highland Park, New Jersey) |
ABSTRACT | Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. |
FILED | Wednesday, July 11, 2007 |
APPL NO | 12/307303 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981871 | Prestwich et al. |
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ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Glenn D. Prestwich (Salt Lake City, Utah); Xiao Zheng Shu (Salt Lake City, Utah); Yanchun Liu (Franklin, Tennessee) |
ABSTRACT | Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking by introduction of at least one hydrazide-reactive group and/or aminooxy-reactive group, and methods of making and using thereof for scar-free wound healing, for delivering bioactive agents or living cells, for preventing adhesion after a surgical procedure or for bone and cartilage repair. The macromolecule can be an oligonucleotide, a necleic acid, a polypeptide, a lipid, a glycoprotein, a glycolipid, a polysaccharide, a protein or a synthetic polymer, preferably a glycosaminoglycan like hyaluronan. |
FILED | Monday, December 06, 2004 |
APPL NO | 10/581571 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981902 | Gangjee |
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APPLICANT(S) | |
ASSIGNEE(S) | Duquesne University of the Holy Ghost (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
ABSTRACT | A compound for treating cancer tumors, particularly ovarian cancer tumors, is described, where a fused cyclic pyrimidine having a cancer treating ability is effective to allow selective delivery to a cancerous tumor. |
FILED | Thursday, June 21, 2007 |
APPL NO | 11/821075 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/265.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981915 | Freedman |
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ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
INVENTOR(S) | Steven D. Freedman (Chestnut Hill, Massachusetts) |
ABSTRACT | This invention features methods for treating diseases associated with mutations in the CFTR gene by administering PPAR agonists, specifically PPARγ, PPARα, and PPARδ agonists, PPAR inducers, and/or antioxidants. Also disclosed are screening methods for identifying therapeutically useful candidate compounds. |
FILED | Monday, October 31, 2005 |
APPL NO | 11/262645 |
ART UNIT | 1614 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/396 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981926 | Ojima |
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ASSIGNEE(S) | Research Foundation of State University of New York (Albany, New York) |
INVENTOR(S) | Iwao Ojima (Port Jefferson, New York) |
ABSTRACT | The invention relates to fluorinated second generation taxoid compounds, pharmaceutical formulations thereof, and their use for inhibiting the growth of cancer cells in a mammal. |
FILED | Friday, August 11, 2006 |
APPL NO | 11/990323 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/449 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981935 | Olson et al. |
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ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Eric Olson (Dallas, Texas); Douglas Frantz (Flower Mound, Texas); Jenny Hsieh (Irving, Texas); Steven L. McKnight (Dallas, Texas); Jay Schneider (Coppell, Texas) |
ABSTRACT | The present invention relates to screens for compounds that can induce stem cell differentiation. In addition, isoxazoles and sulfonyl hydrazones are identified as general classes of compounds that can induce differentiation of stem cells into cells of neuronal and cardiac fate, respectively. |
FILED | Thursday, July 31, 2008 |
APPL NO | 12/183884 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/602 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982002 | Reed et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Burnham Institute for Medical Research (La Jolla, California) |
INVENTOR(S) | John C. Reed (La Jolla, California); Shu-ichi Matsuzawa (La Jolla, California) |
ABSTRACT | In accordance with the present invention, there are provided novel Siah-Mediated-Degradation-Proteins (SMDPS) and/or SCF-Complex Proteins (SCPs). Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention SMDPs and/or SCPs can be employed in a variety of ways, for example, for the production of anti-SMDP and/or SCP antibodies thereto, in therapeutic compositions, and methods employing such proteins and/or antibodies for drug screening, functional genomics and other applications. Also provided are transgenic non-human mammals that express the invention protein. Also provided are compositions and methods for targeting the destruction of selected polypeptides in eukaryotic cells based on the ubiquitin-independent mechanism by which ornithine decarboxylase is degraded by the 26S proteasome. |
FILED | Wednesday, March 04, 2009 |
APPL NO | 12/397468 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982011 | Pastan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Ira H. Pastan (Potomac, Maryland); Mitchell Ho (North Potomac, Maryland); Sookhee Bang (Glendale, California) |
ABSTRACT | Recombinant immunotoxins are fusion proteins composed of the Fv domains of antibodies fused to bacterial or plant toxins. RFB4 (Fv)-PE38 is an immunotoxin that targets CD22 expressed on B cells and B cell malignancies. The present invention provides antibodies and antibody fragments that have improved ability to bind the CD22 antigen compared to RFB4. Immunotoxins made with the antibodies and antibody fragments of the invention have improved cytotoxicity to CD22-expressing cancer cells. Compositions that incorporate these antibodies into chimeric immunotoxin molecules that can be used in medicaments and methods for inhibiting the growth and proliferation of such cancers. Additionally, the invention provides a method of increasing the cytotoxicity of forms of Pseudomonas exotoxin A (“PE”) with the mutation of a single amino acid, as well as compositions of such mutated PEs, nucleic acids encoding them, and methods for using the mutated PEs. |
FILED | Wednesday, November 24, 2004 |
APPL NO | 10/580635 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982023 | Reed et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
INVENTOR(S) | John C. Reed (Rancho Santa Fe, California); Shinichi Takayama (San Diego, California) |
ABSTRACT | The present invention provides a family of BAG-1 related proteins from humans (BAG-1L, BAG-1, BAG-2, BAG-3, BAG-4 and BAG-5), the invertebrate C. elegans (BAG-1, BAG-2) and the fission yeast S. pombe (BAG-1A, BAG-1B) and the nucleic acid molecules that encode them. |
FILED | Tuesday, April 20, 2010 |
APPL NO | 12/764058 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982029 | Ju et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Qinglin Meng (Sunnyvale, California); Dae H. Kim (New York, New York); Lanrong Bi (New York, New York); Xiaopeng Bai (Watertown, Massachusetts); Nicholas J. Turro (Tenafly, New Jersey) |
ABSTRACT | This invention provides a process for making 3′-O-allyl-dGTP-PC-Biodopy-FL-510, 3′-O-allyl-dATP-PC-ROX, 3′-O-allyl-dCTP-PC-Bodipy-650 and 3′-O-allyl-dUTP-PC-R6G, and related methods. |
FILED | Tuesday, October 31, 2006 |
APPL NO | 12/084338 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/25.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982041 | Curran et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Pittsburgh-of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); University of Kentucky Research Foundation (Lexington, Kentucky) |
INVENTOR(S) | Dennis P. Curran (Pittsburgh, Pennsylvania); David Bom (Pittsburgh, Pennsylvania); Thomas G. Burke (Lexington, Kentucky) |
ABSTRACT | A compound having the formula in racemic form, enantiomerically enriched form or enantiomerically pure form, and pharmaceutically acceptable salts thereof. |
FILED | Thursday, April 16, 2009 |
APPL NO | 12/425364 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/115 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982051 | Hanson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Joyant Pharmaceuticals, Inc. (Dallas, Texas) |
INVENTOR(S) | Gunnar Hanson (Chapel Hill, North Carolina); Charles Caldwell (Dallas, Texas); Patrick G. Harran (Los Angeles, California); Susan Harran (Dallas, Texas); Qi Wei (Dallas, Texas); Ming Zhou (Coppell, Texas) |
ABSTRACT | This invention relates to novel macrocyclic lactams intermediates useful for the preparation of diazonamide analogs. This invention also relates to a novel electrochemical oxidative cyclization for the preparation of such macrocyclic lactams, and their further elucidation to provide diazonamide analogs. |
FILED | Sunday, October 03, 2010 |
APPL NO | 12/896898 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 548/236 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982070 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Lloyd M. Smith (Madison, Wisconsin); Michael R. Shortreed (Portage, Wisconsin); Brian L. Frey (Madison, Wisconsin); Margaret F. Phillips (Madison, Wisconsin); Joshua J. Coon (Middleton, Wisconsin); Shane M. Lamos (Winooski, Vermont); Casey J. Krusemark (Woodside, California); Peter J. Belshaw (Madison, Wisconsin); Madhusudan Patel (Somerset, New Jersey); Neil L. Kelleher (Urbana, Illinois) |
ABSTRACT | Relative quantification of metabolites by Electrospray Ionization Mass Spectrometry (ESI-MS) requiring a mechanism for simultaneous analysis of multiple analytes in two or more samples. Labeling reagents that are reactive to particular compound classes and differ only in their isotopic kit facilitating relative quantification and providing tangible evidence for the existence of specific functional groups. Heavy and light isotopic forms of methylacetimidate were synthesized and used as labeling reagents for quantification of amine-containing molecules, such as biological samples. Heavy and light isotopic forms of formaldehyde and cholamine were also synthesized and used independently as labeling reagents for quantification of amine-containing and carboxylic acid-containing molecules, such as found in biological samples. Advantageously, the labeled end-products are positively charged under normal acidic conditions involving conventional Liquid Chromatography Mass Spectrometry (LC/MS) applications. Labeled primary and secondary amine and carboxylic acid end-products also generated higher signals concerning mass-spectra than pre-cursor molecules and improved sensitivity. Improved accuracy concerning relative quantification was achieved by mixing heavy and light labeled Arabidopsis extracts in different ratios. Labeling strategy was further employed to ascertain differences in the amounts of amine-containing metabolites for two strains of Arabidopsis seeds. |
FILED | Wednesday, March 21, 2007 |
APPL NO | 11/726307 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 564/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982370 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Zhong L. Wang (Marietta, Georgia); Xudong Wang (Atlanta, Georgia); Yong Qin (Atlanta, Georgia); Rusen Yang (Atlanta, Georgia) |
ABSTRACT | A small scale electrical generator includes an elongated substrate and a first piezoelectric fine wire. The first piezoelectric fine wire is disposed along a surface of the substrate. The first piezoelectric fine wire has a first end and a spaced-apart second end. A first conductive contact secures the first end of the fine wire to a first portion of the substrate and a second conductive contact secures the second end of the fine wire to a second portion of the substrate. A fabric made of interwoven strands that includes fibers from which piezoelectric nanowires extend radially therefrom and conductive nanostructures extend therefrom is configured to generate electricity. |
FILED | Friday, September 12, 2008 |
APPL NO | 12/209310 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/339 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982462 | Goelman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Gadi Goelman (Rosh Haain, Israel); Oded Gonen (Leonardo, New Jersey) |
ABSTRACT | An exemplary embodiment of system, method, and computer accessible medium for magnetic resonance spectroscopic imaging for improving signal-to-noise ratio per unit time and optimizing duty cycle in MRSI and/or for reducing chemical-shift artifacts can be provided. In one exemplary embodiment, an excitation pulse can be forwarded to the target and acquiring a signal from the target by multiplexing in time and space. The multiplexing procedure in time can involve (i) a segmentation of a field of view of the at least one portion of the target into a predetermined number of slabs that are acquired sequentially during each repetition time, and/or (ii) an acquisition of multiple voxels. Data can be generated based on the acquired signal. According to another exemplary embodiment, an excitation pulse can be provided to the target, and a signal can be acquired from the target. The excitation pulse can be a series of cascaded Hadamard pulse components. Data can be generated based on the acquired signal. |
FILED | Monday, June 09, 2008 |
APPL NO | 12/135837 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/309 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982879 | Desjardins et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Adrien E. Desjardins (Somerville, Massachusetts); Benjamin J. Vakoc (Cambridge, Massachusetts); Guillermo J. Tearney (Cambridge, Massachusetts); Brett Eugene Bouma (Quincy, Massachusetts) |
ABSTRACT | Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations. |
FILED | Wednesday, February 21, 2007 |
APPL NO | 11/677278 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/477 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983736 | Villard et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Joseph W. Villard (St. Louis, Missouri); Thomas E. Milner (Austin, Texas); Marc D. Feldman (San Antonio, Texas); Jeehoon Kim (Evanston, Illinois); Gregory L. Freeman (San Antonio, Texas) |
ABSTRACT | Disclosed are improved methods and compositions for use in light-based in vivo imaging and treatment. The techniques described involve the use of low-scattering, oxygen-carrying blood substitutes in imaging and treatment methods, including OCT imaging. The invention has particular advantages in imaging within the cardiovascular system and highly vascularized or oxygen-dependent tissues. |
FILED | Friday, May 14, 2010 |
APPL NO | 12/780647 |
ART UNIT | 3768 — Optics |
CURRENT CPC | Surgery 6/473 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983740 | Culver et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Joseph Culver (Webster Groves, Missouri); Gavin Perry (Webster Groves, Missouri); Benjamin Zeff (University City, Missouri) |
ABSTRACT | A high performance imaging system for diffuse optical tomography is disclosed. A dense grid utilizing sources, e.g., light emitting diodes (“LEDs”), that achieve high performance at high speed with a high dynamic range and low inter-channel crosstalk are complemented by a system of discrete, isolated receivers, e.g., avalanche photodiodes (“APDs”). The source channels have dedicated reconfigurable encoding control signals, and the detector channels have reconfigurable decoding, allowing maximum flexibility and optimal mixtures of frequency and time encoding and decoding. Each detector channel is analyzed by dedicated, isolated, high-bandwidth receiver circuitry so that no channel gain switching is necessary. The resulting improvements to DOT system performance, e.g., increased dynamic range and decreased crosstalk, enable higher density imaging arrays and provide significantly enhanced DOT image quality. A processor can be utilized to provide sophisticated three dimensional modeling as well as noise reduction. |
FILED | Friday, December 21, 2007 |
APPL NO | 11/962513 |
ART UNIT | 3768 — Optics |
CURRENT CPC | Surgery 6/476 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983743 | Rudy et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); Washington University (St. Louis, Missouri) |
INVENTOR(S) | Yoram Rudy (St. Louis, Missouri); Yong Wang (St. Louis, Missouri); Ping Jia (Solon, Ohio) |
ABSTRACT | Noninvasive systems and methods are provided for determining electrical activity for a heart of a living being. A processor is configured to meshlessly compute data that represents heart electrical activity from a set of noninvasively measured body surface electrical potentials. This is accomplished using data that describes a geometric relationship between a plurality of locations corresponding to where the body surface electrical potentials were measured and the heart. |
FILED | Friday, July 21, 2006 |
APPL NO | 11/996441 |
ART UNIT | 3766 — Optics |
CURRENT CPC | Surgery 6/509 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 07980054 | Suciu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | Gabriel L. Suciu (Glastonbury, Connecticut); Gary D. Roberge (Tolland, Connecticut) |
ABSTRACT | A tip turbine engine (10) includes a combustor (30) radially outward of a fan. In order to reduce the heat transfer from the combustor and the high-energy gas stream generated by the combustor, a cold air ejector (38) radially outward of the combustor extends from a forward end of the nacelle (12) to a point rearward of the combustor and an exhaust mixer (110). The cold air ejector includes an annular inlet (17) at the forward end of the nacelle. The cold air ejector draws air over the outer engine case (39) to provide a boundary between the nacelle and the hot outer engine case. The layer of air being pulled past the engine case ejects the heat, thereby preventing the heat from escaping into the nacelle or engine bay. |
FILED | Wednesday, December 01, 2004 |
APPL NO | 11/720083 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Power plants 060/39.430 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980063 | Cooke |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Delphi Technologies Holdings S.arl (Troy, Michigan) |
INVENTOR(S) | Michael P. Cooke (Gillingham, United Kingdom) |
ABSTRACT | A dosing device is provided that is suitable for administering a reagent into an exhaust chamber of an internal combustion engine. The device comprises a nozzle body and an insulating jacket wherein the jacket is mounted to the nozzle body at one or more mounting points, and wherein the dosing device is adapted to engage with a port located in the wall of an exhaust chamber. The insulating jacket defines a compartment, which can comprise an insulating material or can be substantially evacuated. The dosing device of the invention is advantageously insulated from the elevated temperatures in the surrounding environment, thereby allowing for the reagent to be maintained at an optimal working temperature range. |
FILED | Wednesday, July 11, 2007 |
APPL NO | 11/827317 |
ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Power plants 060/286 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980149 | Godfrey et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Inverness Medical Switzerland GmbH (Zug, Switzerland) |
INVENTOR(S) | Daniel Peterson Godfrey (Cambridge, United Kingdom); Mark John Frogley (Huntington, United Kingdom); Christopher Durham Whalen (Pleasant Prairie, Wisconsin) |
ABSTRACT | A docking mechanism provided for analytical apparatus, such as an acoustic bio-sensor apparatus. The mechanism is operable releasably to receive a cartridge (58) for use in analysing a sample comprising a fluid and having a flow cell (104, 106; 304, 306) for the sample and an electrically operated sensor (92) for performing the analysis. The docking mechanism has a clamping mechanism (12, 8, 10) for urging a fluid connector such as ferules (50, 52) against the cartridge to provide a fluid connection between the flow cell inlet and a sample delivery device. The docking mechanism also has an electrical connector (74, 76, 78) for engaging the sensor to connect the latter to electrical circuitry for operating the sensor, the electrical connector being moveable towards and away from the sensor relative to the clamping mechanism, so that, in use, the electrical connector exerts on the sensor a force which is sufficient to maintain the necessary electrical connection, while not being so great as to have a substantial detrimental effect on the accuracy of the sensor. There is also shown analytical apparatus which includes such a docking mechanism. |
FILED | Friday, March 31, 2006 |
APPL NO | 11/817853 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/864.850 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980158 | Centrella |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | John Centrella (Wharton, New Jersey) |
ABSTRACT | A press punch for pressing a powder includes a generally cylindrical metallic body and a polyurethane layer disposed around the metallic body. The metallic body has a nominal outside diameter and a generally flat bottom face. The polyurethane layer is disposed around the metallic body such that a bottom of the polyurethane layer is flush with the generally flat bottom face of the metallic body and an outside diameter of the polyurethane layer is substantially the same as the nominal outside diameter of the metallic body. In another embodiment, the outside diameter of the polyurethane layer is greater than the nominal outside diameter of the metallic body. |
FILED | Wednesday, April 09, 2008 |
APPL NO | 12/099968 |
ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal tools and implements, making 076/107.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980178 | Yalamanchili et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Rao Yalamanchili (Flanders, New Jersey); Michael E. Ellis (Lake Hopatcong, New Jersey) |
ABSTRACT | A cartridge containing an environmentally friendly percussion primer employing a primer explosive mixture, packed under the paper disc and anvil; the mixture being a metastable interstitial composite (MIC) and a high explosive; and a second mass of high explosive, packed within the primer cup above the anvil—which mass of high explosive is ignited by the detonation of the MIC and high explosive mixture—thereby adding to the detonation to create a combined, enhanced pressure and temperature wave to more quickly initiate the booster pellet and propellant, to fire the bullet within the subject action time limit—even under extreme cold ambient conditions. |
FILED | Friday, February 12, 2010 |
APPL NO | 12/704707 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition and explosives 12/204 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980335 | Potter |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Foster-Miller, Inc. (Waltham, Massachusetts) |
INVENTOR(S) | Steven D. Potter (Bedford, Massachusetts) |
ABSTRACT | An omni-directional wheel includes a hub rotatable about a wheel axis and a first row of angled rollers about the hub each rotatably supported by the hub. There is at least a second row of angled rollers about the hub each also rotatably supported by the hub. The rollers of the second row are axially offset along the wheel axis from the first row, and rotationally offset from the first row about the wheel axis, and not coaxial with the rollers of the first row. |
FILED | Monday, January 26, 2009 |
APPL NO | 12/321903 |
ART UNIT | 3611 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Motor vehicles 180/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980522 | Anderson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Alion Science and Technology Corporation (McLean, Virginia) |
INVENTOR(S) | Benjamin W. Anderson (Saint Croix Falls, Wisconsin); Eric Peterson (Saint Croix Falls, Wisconsin) |
ABSTRACT | A blade clamp for a helicopter blade having a width and leading and trailing edges includes a first clamping part, a first flexible liner attachable to the first clamping part, a second clamping part, a second flexible liner attachable to the second clamping part, a hinge mechanism to pivot the first clamping part and the first flexible liner with respect to the second clamping part and the second flexible liner and a connector provided opposite to the hinge mechanism. The flexible liners evenly distribute clamping force upon the blade clamp to prevent damage to the blade. The hinge mechanism allows the first and second clamping parts to open wide enough to safely and easily accommodate a helicopter blade during removal and installation of the blade. |
FILED | Friday, December 28, 2007 |
APPL NO | 12/005611 |
ART UNIT | 3632 — Static Structures, Supports and Furniture |
CURRENT CPC | Supports 248/316.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980765 | Reitz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Ronald P. Reitz (Spring Hill, Florida); Gus F. Plangetis (Annapolis, Maryland) |
ABSTRACT | The present invention, as variously practiced, implements electrorheological fluid (ERF) as a bearing lubricant. Various modes of an inventive rolling element bearing apparatus provide for electrification of inventive electrode components, viz: (first mode) two annular disk electrodes, opposite each other and perpendicular to the two raceway surfaces; or, (second mode) electrically conductive inner and outer races, having an electrically conductive spacer therebetween; or, (third mode) plural electrodes, radially embedded in a race. An ERF lubricative coating remains on one or both raceway surfaces in accordance with Winslow effect principle (first and second modes) or edge effect principle (third mode). An inventive journal bearing apparatus provides for electrification of electrodes that are axially-longitudinally embedded in a journal bearing member, resulting in establishment of edge effect electric flux lines between adjacent electrode pairs, an ERF lubricative coating thereby remaining on the journal bearing member's inward facing surface, contiguous to the shaft. |
FILED | Friday, June 11, 2010 |
APPL NO | 12/813643 |
ART UNIT | 3656 — Material and Article Handling |
CURRENT CPC | Bearings 384/322 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07980812 | McMahon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
INVENTOR(S) | Ryan C. McMahon (North Palm Beach, Florida); Jack W. Wilson, Jr. (Palm Beach Gardens, Florida) |
ABSTRACT | A low pressure turbine rotor disk for a small twin spool gas turbine engine in which the rotor disk includes a forward side cavity large enough to allow for the bearing assembly that rotatably supports the rotor disk to fit within the cavity in order to shorten the axial distance between the bearings that support the inner rotor shaft on which the turbine rotor disk is secured. Minimizing the bearings spacing allows for a high critical speed for the inner rotor shaft and therefore allows for the small twin spool gas turbine engine to operate at this small scale. The turbine rotor disk also includes a plurality of axial aligned cooling air holes to allow for cooling air from the bearings to flow out from the aft end of the rotor disk. The inner surface of the cavity is an annular surface that forms a seal with knife edges extending outward from the bearing support plate also located within the cavity. The rotor disk includes an annular groove facing outward and on the rear side of the disk to allow for a tool to be inserted for removing the rotor disk from the shaft. An axial central opening in the rotor disk allows for insertion of the shaft and is formed with a bearing race abutment surface on the forward side and a nut abutment surface of the aft side used to compress the rotor disk assembly on the inner rotor shaft. |
FILED | Friday, October 19, 2007 |
APPL NO | 11/975674 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Rotary kinetic fluid motors or pumps 415/110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981225 | Mehta et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Neha Mehta (Succasunna, New Jersey); Gartumg Cheng (Edison, New Jersey); Emily A. Cordaro (Hopatcong, New Jersey); Neelam Mehta (Bel Air, Maryland); Carl Hu (Parsippany, New Jersey); Robert Lateer (Ogdensburg, New Jersey); Daniel Stec, III (Long Valley, New Jersey); Raja G. Duddu (Hackettstown, New Jersey); Paritosh R. Dave (Bridgewater, New Jersey); Kathy Yang (Roxbury, New Jersey) |
ABSTRACT | A lead-free primer energetic composition including Cyanuric Triazide (60%), Tetracene (5%), Barium Nitrate (20%) and Antimony Trisulfide (15%) is produced. The lead-free primer energetic composition is used to construct a primary detonator including a transfer charge of Cyanuric Triazide, which produces a further initiation train that may subsequently detonate a secondary explosive, i.e., HDX, RDX, or a pyrotechnic device. |
FILED | Thursday, October 19, 2006 |
APPL NO | 11/550986 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosive and thermic compositions or charges 149/35 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981365 | Hart et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Matthew Hart (Alexandria, Virginia); Horn Bond Lin (Fairfax, Virginia); Jay Eversole (Woodbridge, Virginia) |
ABSTRACT | A device having an air sampler, an electrospray apparatus, and a fluorescence excitation and detection system. The air sampler is capable of moving air suspected of containing a biological or chemical aerosol particle into a chamber. The electrospray apparatus is capable of spraying a charged solution into the chamber to coat the aerosol particles with a coating. The solution has a fluorescent-labeled biological or chemical marker capable of specific binding to the aerosol particle. The fluorescence system is capable of detecting fluorescence of the fluorescent label in the coating. A method of detecting the aerosol particle by: moving air suspected of containing the aerosol particle into a chamber; spraying the charged solution into the chamber with an electrospray apparatus, such that a coating of the solution is formed around the particle; exciting the fluorescent label; and detecting fluorescence of the fluorescent label. |
FILED | Thursday, September 15, 2005 |
APPL NO | 11/229431 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/88 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981392 | Kouvetakis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Arizona Board of Regents, a body corporate of the state of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter, III (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-XSiHX, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HXSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HXSi(OSO2CF3)4-x or HXSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
FILED | Friday, December 31, 2004 |
APPL NO | 11/662722 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981432 | Singh et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Shrewsbury, Massachusetts) |
INVENTOR(S) | Bal Ram Singh (Dartmouth, Massachusetts); Zhong Zhang (New Bedford, Massachusetts) |
ABSTRACT | The invention features a polypeptide complex synthesized by bacteria of the genus Clostridia that contains the serotype E botulinum neurotoxin and five neurotoxin associated polypeptides having molecular weights of about 118, 80, 65, 40, and 18 kDa, respectively. The complex is useful in the treatment of diseases or conditions that are caused by excessive release of acetylcholine from presynaptic nerve terminals. |
FILED | Tuesday, October 07, 2008 |
APPL NO | 12/247124 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/239.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981438 | Lan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Que Lan (Madison, Wisconsin); Min-Sik Kim (Madison, Wisconsin) |
ABSTRACT | Methods of killing mosquito larvae and controlling an adult mosquito population by using α-mangostin, 3,6,8-yrihydroxy-2-methoxy-1,7-bis(3-methylbut-2-enyl)xanthen-9-one, or a salt, solute, hydrate or solvate thereof. Mosquito larvae are killed by contacting a lethal dose of α-mangostin with mosquito larvae. Adult mosquito populations are controlled by treating a mosquito larvae population with a lethal dose of α-mangostin. |
FILED | Friday, May 30, 2008 |
APPL NO | 12/130134 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/405 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981444 | Tomalia et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Dendritic Nanotechnologies, Inc. (Midland, Michigan) |
INVENTOR(S) | Donald A. Tomalia (Midland, Michigan); Douglas R. Swanson (Mt. Pleasant, Michigan); Baohua Huang (Mt. Pleasant, Michigan); Veera Reddy Pulgam (Mt. Pleasant, Michigan) |
ABSTRACT | Poly(ester-acrylate) and poly(ester/epoxide) dendrimers. These materials can be synthesized by utilizing the so-called “sterically induced stoichiometric” principles. The preparation of the dendrimers is carried out by reacting precursor amino/polyamino-functional core materials with various branch cell reagents. The branch cell reagents are dimensionally large, relative to the amino/polyamino-initiator core and when reacted, produce generation=1 dendrimers directly in one step. There is also a method by which the dendrimers can be stabilized and that method is the reaction of the dendrimers with surface reactive molecules to pacify the reactive groups on the dendrimers. |
FILED | Wednesday, April 20, 2005 |
APPL NO | 10/594776 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981618 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Dihua Yu (Houston, Texas); Xiaoyan Zhou (Shanghai, China PRC); Yoichi Nagata (Tosu, Japan); Francisco J. Esteva (Bellaire, Texas); Aysegul A. Sahin (Houston, Texas) |
ABSTRACT | Patients with ErbB2-overexpressing cancers can be given an ErbB2 targeting agent as a therapeutic regimen but not all patients are responsive. The present invention concerns the diagnostic, prognostic and therapeutic methods and compositions for evaluating potential efficacy of an ErbB2 targeting agent in an ErbB2-overexpressing cancers by evaluating PTEN expression, which is predictive of responsiveness or resistance to ErbB2 targeting agents such as trastuzumab. Low PTEN expression is predictive of a patient who will respond poorly to trastuzumab. |
FILED | Friday, November 05, 2004 |
APPL NO | 10/983011 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981649 | Wikswo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Franz J. Baudenbacher (Franklin, Tennessee); Owen McGuiness (Brentwood, Tennessee) |
ABSTRACT | A device and methods for monitoring status of at least one cell, wherein the cell has a membrane forming a substantially enclosed structure and defining an intracellular space therein. In one embodiment of the present invention, the device includes a first substrate having a first surface and an opposite second surface, a second substrate supported by the first substrate, the second substrate having a first surface, an opposite second surface, a body portion between the first surface and the second surface, a first side surface and an opposite second side surface, wherein the body portion defines a first passage between the first side surface and the second side surface and an opening on the first surface of the second substrate and in fluid communication with the first passage, and sidewalls positioned above the first surface of the second substrate. In one operation mode, when a first medium is introduced into the first passage, the intracellular space of the cell is in fluid communication with the first passage with the first medium, a sensor measures the response of the cell to the first medium. |
FILED | Friday, August 22, 2008 |
APPL NO | 12/229503 |
ART UNIT | 1775 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/173.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981814 | Schaper |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Charles Daniel Schaper (Union City, California) |
ABSTRACT | A method for the duplication of microscopic patterns from a master to a substrate is disclosed, in which a replica of a topographic structure on a master is formed and transferred when needed onto a receiving substrate using one of a variety of printing or imprint techniques, and then dissolved. Additional processing steps can also be carried out using the replica before transfer, including the formation of nanostructures, microdevices, or portions thereof. These structures are then also transferred onto the substrate when the replica is transferred, and remain on the substrate when the replica is dissolved. This is a technique that can be applied as a complementary process or a replacement for various lithographic processing steps in the fabrication of integrated circuits and other microdevices. |
FILED | Friday, August 31, 2007 |
APPL NO | 11/848669 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/788 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982039 | Marks et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Michael R. Wasielewski (Glenview, Illinois); Antonio Facchetti (Chicago, Illinois); Michael J. Ahrens (Evanston, Illinois); Brooks A. Jones (Evanston, Illinois); Myung-Han Yoon (Evanston, Illinois) |
ABSTRACT | Mono- and diimide perylene and naphthalene compounds, N- and/or core-substituted with electron-withdrawing groups, for use in the fabrication of various device structures. |
FILED | Tuesday, December 29, 2009 |
APPL NO | 12/648484 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/38 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982130 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Michael S. Arnold (Ann Arbor, Michigan); Jeramy D. Zimmerman (Ann Arbor, Michigan) |
ABSTRACT | A photovoltaic device includes a photoactive region disposed between and electrically connected to two electrodes where the photoactive region includes photoactive polymer-wrapped carbon nanotubes that create excitons upon absorption of light in the range of about 400 nm to 1400 nm. |
FILED | Friday, January 09, 2009 |
APPL NO | 12/351378 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/263 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982208 | Craven et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Michael D. Craven (Goleta, California); Stacia Keller (Goleta, California); Steven P. Denbaars (Goleta, California); Tal Margalith (Santa Barbara, California); James Stephen Speck (Goleta, California); Shuji Nakamura (Santa Barbara, California); Umesh K. Mishra (Santa Barbara, California) |
ABSTRACT | A method for forming non-polar (Al,B,In,Ga)N quantum well and heterostructure materials and devices. Non-polar (11 |
FILED | Wednesday, June 21, 2006 |
APPL NO | 11/472033 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/14 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982296 | Nuzzo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Ralph G. Nuzzo (Champaign, Illinois); John A. Rogers (Champaign, Illinois); Etienne Menard (Durham, North Carolina); Keon Jae Lee (Daejeon, South Korea); Dahl-Young Khang (Urbana, Illinois); Yugang Sun (Champaign, Illinois); Matthew Meitl (Raleigh, North Carolina); Zhengtao Zhu (Urbana, Illinois) |
ABSTRACT | The invention provides methods and devices for fabricating printable semiconductor elements and assembling printable semiconductor elements onto substrate surfaces. Methods, devices and device components of the present invention are capable of generating a wide range of flexible electronic and optoelectronic devices and arrays of devices on substrates comprising polymeric materials. The present invention also provides stretchable semiconductor structures and stretchable electronic devices capable of good performance in stretched configurations. |
FILED | Tuesday, September 22, 2009 |
APPL NO | 12/564566 |
ART UNIT | 2829 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/679 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982434 | Kimball et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | SolarBridge Technologies, Inc. (Austin, Texas) |
INVENTOR(S) | Jonathan W. Kimball (Rolla, Missouri); Philip T. Krein (Champaign, Illinois); Nicholas D. Benavides (Champaign, Illinois) |
ABSTRACT | In an electrical power supply having a plurality of switching power converter circuits and configured to supply a voltage to an electrical load, a method of controlling a duty cycle of at least one switch of one of the plurality of switching power converter circuits includes determining a storage voltage produced by the one of the plurality of energy storage devices. The method further includes determining an average storage voltage corresponding to an average of storage voltages produced by each of the plurality of energy storage devices. The method further includes determining at least one control signal as a function of the storage voltage, the average storage voltage, and a reference voltage. The method further includes controlling the duty cycle of the at least one switch of the one of the plurality of switching power converter circuits based upon the at least one control signal. |
FILED | Wednesday, February 03, 2010 |
APPL NO | 12/699410 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/132 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982439 | Trainor et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | TPL, Inc. (Albuquerque, New Mexico) |
INVENTOR(S) | John T. Trainor (Albuquerque, New Mexico); Patrick Franz Fleig (Albuquerque, New Mexico); Charles D. E. Lakeman (Albuquerque, New Mexico); Jenniffer Leigh DeGreeff (Albuquerque, New Mexico) |
ABSTRACT | A device and method for harvesting, generating, storing, and delivering energy to a load, particularly for remote or inaccessible applications. The device preferably comprises one or more energy sources, at least one supercapacitor, at least one rechargeable battery, and a controller. The charging of the energy storage devices and the delivery of power to the load is preferably dynamically varied to maximize efficiency. A low power consumption charge pump circuit is preferably employed to collect power from low power energy sources while also enabling the delivery of higher voltage power to the load. The charging voltage is preferably programmable, enabling one device to be used for a wide range of specific applications. |
FILED | Thursday, April 01, 2010 |
APPL NO | 12/752593 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/166 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982476 | Koons et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Micah S. Koons (Plano, Texas); Donald R. Tolbert (McKinney, Texas); Mark A. Taylor (McKinney, Texas); Scott J. Martin (Richardson, Texas) |
ABSTRACT | According to one embodiment of the invention, a testing apparatus for executing highly accelerated life testing on at least one test subject includes at least one structure operable to thermally stress the test subject via conduction and at least one pneumatic hammer operable to input imparting vibrations to the test subject. According to another embodiment of the invention, a method for executing highly accelerated life testing of at least one test subject includes applying a thermal stress to the test subject via conduction at a rate of change of at least 8° C. per minute and imparting vibrations to the test subject at a rate of at least 3 Gs rms. |
FILED | Thursday, January 29, 2009 |
APPL NO | 12/361886 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/750.50 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982513 | Carangelo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | MKS Instruments, Inc. (Andover, Massachusetts) |
INVENTOR(S) | Robert M. Carangelo (Glastonbury, Connecticut); Paul C. Jette (Bethel, Connecticut); Jack Kisslinger (Verona, Wisconsin) |
ABSTRACT | Eight or more transition points are generated during a given period, and are used in tracking movement of an interferometer reflector. Duty cycles of generated square waves are used to establish precise intervals between the transition points, and precise wave-phase relationships. |
FILED | Monday, March 15, 2010 |
APPL NO | 12/661302 |
ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/184 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982664 | Uscinowicz |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Michael B. Uscinowicz (Hainesport, New Jersey) |
ABSTRACT | A radar system with an array antenna includes various signal paths, including beamformers, extending between an exciter, a receiver, and the array antenna. The signal paths are calibrated by a method that includes frequency modulation of the exciter signals that reach the “antenna” and additional amplitude modulation of signals just as they enter the receiver. Leakage paths directly from the exciter to the receiver are unmodulated, those extending from the exciter through the beamformer are amplitude modulated, and only those reaching the “antenna” and returning to the receiver are both amplitude and frequency modulated. The receiver is tuned to receive only the “doubly-modulated” signals, which tends to reject leakage signals. |
FILED | Wednesday, May 27, 2009 |
APPL NO | 12/472864 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/174 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982878 | Ja |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Nomadics, Inc. (Stillwater, Oklahoma) |
INVENTOR(S) | Shiou-jyh Ja (Stillwater, Oklahoma) |
ABSTRACT | This invention generally relates to optical devices that can collect and detect signal emissions effectively while allowing the excitation light path and the sample flow path to coexist non-obstructively in a compact format. More specifically, this invention relates to a compact device having a multilayer coating on the structure surface and a wave guiding structure. In the device, using the surface plasmon coupling effect, the majority of the optical emission from the emitter on top of the multilayer coating is distributed toward the wave guiding structure. The wave guiding structure then further directs the emission signal to the detector with a high efficiency. |
FILED | Friday, October 03, 2008 |
APPL NO | 12/245574 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/445 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982883 | Cui et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Xiquan Cui (Pasadena, California); Xin Heng (Somerville, Massachusetts); Changhuei Yang (Pasadena, California); Axel Scherer (Laguna Beach, California); Demetri Psaltis (Lausanne, Switzerland) |
ABSTRACT | A differential interference contrast (DIC) determination device and method utilizes an illumination source, a layer having a pair of two apertures that receive illumination from the illumination source, and a photodetector to receive Young's interference from the illumination passing through the pair of two apertures. In addition, a surface wave assisted optofluidic microscope and method utilize an illumination source, a fluid channel having a layer with at least one aperture as a surface, and a photodetector that receives a signal based on the illumination passing through the aperture. The layer is corrugated (e.g., via fabrication) and parameters of the corrugation optimize the signal received on the photodetector. |
FILED | Friday, June 25, 2010 |
APPL NO | 12/823201 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/521 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982983 | Sanghera et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jasbinder S. Sanghera (Ashburn, Virginia); Catalin M Florea (Washington, District of Columbia); Ishwar D. Aggarwal (Fairfax Station, Virginia) |
ABSTRACT | Beam steering apparatus is presented having a Risley double-prism pair with first and second double-prisms disposed along an optical path, where one or more of the prisms are made from a chalcogenide glass material. |
FILED | Monday, April 27, 2009 |
APPL NO | 12/430162 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/834 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983135 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
INVENTOR(S) | Shih-Yuan Wang (Palo Alto, California); R. Stanley Williams (Portola Valley, California) |
ABSTRACT | An optical system includes an optical recording medium configured to store data and a light device configured to emit a beam of light to write the data to the optical recording medium or read the data from the optical recording medium. The optical system also includes a superlens positioned between the optical recording medium and the light device. The superlens is configured to focus the beam of light emitted from the light device to create a focused beam of light on the optical recording medium. |
FILED | Thursday, October 16, 2008 |
APPL NO | 12/253136 |
ART UNIT | 2627 — Selective Visual Display Systems |
CURRENT CPC | Dynamic information storage or retrieval 369/112.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
07983239 — Systems and methods for constructing a virtual model of a multi-hop, multi-access network
US 07983239 | Weinstein et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
INVENTOR(S) | Joseph J. Weinstein (Somerville, Massachusetts); Vladimir Rosenzweig (Belmont, Massachusetts); Isidro Marcos Castineyra (Somerville, Massachusetts); Jonathan Shapiro (Framingham, Massachusetts) |
ABSTRACT | A system constructs an OSPF-compatible virtual model of a multi-hop, multi-access packet radio network that includes a plurality of routers (120) and which includes its own private, internal routing system (150), in order to facilitate the incorporation of that packet radio network into an overall OSPF routing environment. The system determines a network graph identifying actual connectivity among the plurality of routers (120). The system constructs a virtual model (300) of the, wherein connectivity of the virtual model may be different than the actual connectivity of the network graph. The system represents the multi-hop, multi-access radio network in the virtual model as a set of multi-access links (305, 310), point-to-point links, AS-external routes, and area summary routes. The system employs the virtual model for routing purposes and advertises the virtual model to other OSPF routers for the same purpose. |
FILED | Wednesday, January 07, 2004 |
APPL NO | 10/752988 |
ART UNIT | 2473 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/351 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983756 | Nicolelis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Miguel A. L. Nicolelis (Chapel Hill, North Carolina); Gary C. Lehew (Durham, North Carolina); David J. Krupa (Durham, North Carolina) |
ABSTRACT | A high-density multichannel microwire electrode array is disclosed. The array can comprise a variable number of electrodes. A method of assembling the array is further disclosed. Additionally, a plurality of devices employing the array are disclosed, including an intelligent brain pacemaker and a closed loop brain machine interface. |
FILED | Tuesday, October 18, 2005 |
APPL NO | 11/252953 |
ART UNIT | 3766 — Optics |
CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983890 | Bliss et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Nadya Travinin Bliss (Cambridge, Massachusetts); Henry Hoffman (Somerville, Massachusetts) |
ABSTRACT | A method, apparatus and computer program product for mapping and executing an application on a multi-processor system is presented. At least one array to be considered for distribution among processors of said multi-processor system is indicated. The application is mapped according to a performance model associated with benchmark performance data of a parallel library on a parallel computer architecture. Then either the application is executed on the multi-processor system, or the application is simulated using a specified machine model for a multiprocessor system. Feedback information is then provided to influence architecture parameters for a multiprocessor system. |
FILED | Monday, June 16, 2008 |
APPL NO | 12/139802 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983997 | Allen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Florida Institute for Human and Machine Cognition, Inc. (Pensacola, Florida) |
INVENTOR(S) | James F. Allen (Pensacola, Florida); Nathanael Chambers (Stanford, California); Lucian Galescu (Pensacola, Florida); Hyuckchul Jung (Gulf Breeze, Florida); William Taysom (Pensacola, Florida) |
ABSTRACT | A system which allows a user to teach a computational device how to perform complex, repetitive tasks that the user usually would perform using the device's graphical user interface (GUI) often but not limited to being a web browser. The system includes software running on a user's computational device. The user “teaches” task steps by inputting natural language and demonstrating actions with the GUI. The system uses a semantic ontology and natural language processing to create an explicit representation of the task that is stored on the computer. After a complete task has been taught, the system is able to automatically execute the task in new situations. Because the task is represented in terms of the ontology and user's intentions, the system is able to adapt to changes in the computer code while still pursuing the objectives taught by the user. |
FILED | Friday, November 02, 2007 |
APPL NO | 11/982668 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Artificial intelligence 76/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07984293 | Winslow |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | L3 Communications Corporation (New York, New York) |
INVENTOR(S) | Richard Norman Winslow (Wilmington, Delaware) |
ABSTRACT | A Personal Computer Memory Card International Association (PCMCIA) card may establish, via a non-secure network, a secure communications channel between a computer and a secure network. The non-secure network may define a first address space. The secure network may define a second address space. The PCMCIA card may include a cryptography module, a network adapter, and/or a processor. The cryptography module may provide Type 1 cryptography of data communicated between the computer and the secure network. The network adapter may be in communication with the non-secure network and may be associated with a first network address from the first address space. The processor may be in communication with the secure network via the cryptography module and the network adapter. The processor may identify a second network address for the computer from the second address space and may communicate the second network address to the computer, for example via dynamic host control protocol (DHCP). |
FILED | Friday, July 13, 2007 |
APPL NO | 11/777549 |
ART UNIT | 2431 — Cryptography and Security |
CURRENT CPC | Electrical computers and digital processing systems: Support 713/162 |
VIEW PATENT | @ USPTO: Full Text PDF |
US RE42561 | Adachi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The University of Southern California (Los Angeles, California); The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Chihaya Adachi (Fukuoka, Japan); Marc A. Baldo (Cambridge, Massachusetts); Stephen R. Forrest (Ann Arbor, Michigan) |
ABSTRACT | An organic light emitting device structure having an organic light emitting device (OLED) over a substrate, where the OLED has, for example, an anode, a hole transporting layer (HTL), a first electron transporting layer (ETL) that is doped with a phosphorescent material, a second electron transporting layer (ETL), and a cathode. The OLEDs of the present invention are directed, in particular, to devices that include an emissive layer comprised of an electron transporting host material having a triplet excited state energy level that is higher than the emissive triplet excited state energy level of the phosphorescent dopant material. |
FILED | Monday, April 16, 2007 |
APPL NO | 11/787753 |
ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/690 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 07980828 | Lantz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Jeffrey W. Lantz (Albuquerque, New Mexico); Harold L. Stalford (Norman, Oklahoma) |
ABSTRACT | A microelectromechanical (MEM) pump is disclosed which includes a porous silicon region sandwiched between an inlet chamber and an outlet chamber. The porous silicon region is formed in a silicon substrate and contains a number of pores extending between the inlet and outlet chambers, with each pore having a cross-section dimension about equal to or smaller than a mean free path of a gas being pumped. A thermal gradient is provided along the length of each pore by a heat source which can be an electrical resistance heater or an integrated circuit (IC). A channel can be formed through the silicon substrate so that inlet and outlet ports can be formed on the same side of the substrate, or so that multiple MEM pumps can be connected in series to form a multi-stage MEM pump. The MEM pump has applications for use in gas-phase MEM chemical analysis systems, and can also be used for passive cooling of ICs. |
FILED | Wednesday, April 25, 2007 |
APPL NO | 11/739716 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Pumps 417/207 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981198 | Gonze et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | GM Global Technology Operations LLC (, None) |
INVENTOR(S) | Eugene V. Gonze (Pinckney, Michigan); Mark R. Chapman (Brighton, Michigan) |
ABSTRACT | A system includes a particulate matter (PM) filter that includes an upstream end for receiving exhaust gas and a downstream end. A zoned heater is arranged spaced from the upstream end and comprises N zones, where N is an integer greater than one, wherein each of the N zones comprises M sub-zones, where M is an integer greater than or equal to one, and wherein the N zones and the M sub-zones are arranged in P layers, where P is an integer greater than one. A control module selectively activates at least a selected one of the N zones to initiate regeneration in downstream portions of the PM filter from the one of the N zones and deactivates non-selected ones of the N zones. |
FILED | Friday, January 11, 2008 |
APPL NO | 11/972716 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/283 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981261 | Rajh et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Tijana Rajh (Naperville, Illinois); YuPo Lin (Naperville, Illinois); Nada Dimitrijevic (Downers Grove, Illinois); Seth W. Snyder (Lincolnwood, Illinois); Norman F. Sather (Naperville, Illinois) |
ABSTRACT | The invention provides a system for separating oppositely-charged charge carriers, the substrate comprising a semiconductor; a ligand in electrical communication with said semiconductor; an ion-exchange resin attached to the semiconductor; an ion-exchange membrane; and an electrical conduit attaching said resin to said membrane. Also provided is a method for producing hydrogen gas, comprising: inducing charge separation in semiconductor particles so as to produce electrons and holes; oxidizing water with the holes to produce oxygen ions and protons, wherein the protons are sequestered from the oxygen ions as the protons are produced; and directing the sequestered protons to a cathode. The invention also provides a method to produce electricity comprising, inducing charge separation in semiconductor particles so as to produce electrons and holes, and completing the circuit with an electron hole transporter. |
FILED | Tuesday, November 28, 2006 |
APPL NO | 11/605840 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical and wave energy 24/252 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981268 | Bourcier et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | William L. Bourcier (Livermore, California); Roger D. Aines (Livermore, California); Jeffery J. Haslam (Livermore, California); Charlene M. Schaldach (Pleasanton, California); Kevin C. O'Brien (San Ramon, California); Edward Cussler (Edina, Minnesota) |
ABSTRACT | The present invention provides a new method and apparatus/system for purifying ionic solutions, such as, for example, desalinating water, using engineered charged surfaces to sorb ions from such solutions. Surface charge is applied externally, and is synchronized with oscillatory fluid movements between substantially parallel charged plates. Ions are held in place during fluid movement in one direction (because they are held in the electrical double layer), and released for transport during fluid movement in the opposite direction by removing the applied electric field. In this way the ions, such as salt, are “ratcheted” across the charged surface from the feed side to the concentrate side. The process itself is very simple and involves only pumps, charged surfaces, and manifolds for fluid collection. |
FILED | Friday, January 19, 2007 |
APPL NO | 11/655423 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical and wave energy 24/666 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981319 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Yu Seung Kim (Los Alamos, New Mexico); Kwan-Soo Lee (Blacksburg, Virginia); Tommy Q. T. Rockward (Rio Rancho, New Mexico) |
ABSTRACT | Compositions, and methods of making thereof, comprising from about 1% to about 5% of a perfluorinated sulfonic acid ionomer or a hydrocarbon-based ionomer; and from about 95% to about 99% of a solvent, said solvent consisting essentially of a polyol; wherein said composition is substantially free of water and wherein said ionomer is uniformly dispersed in said solvent. |
FILED | Thursday, March 19, 2009 |
APPL NO | 12/383279 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Compositions 252/182.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981774 | Grier et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | David G. Grier (New York, New York); Yael Roichman (New York, New York); Weining Man (Princeton, New Jersey); Paul Michael Chaikin (Pennington, New Jersey); Paul Joseph Steinhardt (Princeton, New Jersey) |
ABSTRACT | A method and system for assembling a quasicrystalline heterostructure. A plurality of particles is provided with desirable predetermined character. The particles are suspended in a medium, and holographic optical traps are used to position the particles in a way to achieve an arrangement which provides a desired property. |
FILED | Friday, July 07, 2006 |
APPL NO | 11/483021 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/479 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981835 | Srinivasachar et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Energy and Environmental Research Center Foundation (Grand Forks, North Dakota) |
INVENTOR(S) | Srivats Srinivasachar (Sturbridge, Massachusetts); Steven Benson (Grand Forks, North Dakota); Charlene Crocker (Newfolden, Minnesota); Jill Mackenzie (Carmel, Indiana) |
ABSTRACT | A system and method for producing activated carbon comprising carbonizing a solid carbonaceous material in a carbonization zone of an activated carbon production apparatus (ACPA) to yield a carbonized product and carbonization product gases, the carbonization zone comprising carbonaceous material inlet, char outlet and carbonization gas outlet; activating the carbonized product via activation with steam in an activation zone of the ACPA to yield activated carbon and activation product gases, the activation zone comprising activated carbon outlet, activation gas outlet, and activation steam inlet; and utilizing process gas comprising at least a portion of the carbonization product gases or a combustion product thereof; at least a portion of the activation product gases or a combustion product thereof; or a combination thereof in a solid fuel boiler system that burns a solid fuel boiler feed with air to produce boiler-produced steam and flue gas, the boiler upstream of an air heater within a steam/electricity generation plant, said boiler comprising a combustion zone, a boiler-produced steam outlet and at least one flue gas outlet. |
FILED | Wednesday, May 14, 2008 |
APPL NO | 12/120639 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/423 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982069 | Jessop et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Queen's University at Kingston (Kingston, Canada); Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Philip G. Jessop (Kingston, Canada); Charles A. Eckert (Atlanta, Georgia); Charles L. Liotta (Atlanta, Georgia); David J. Heldebrant (Richland, Washington) |
ABSTRACT | A solvent that reversibly converts from a nonionic liquid mixture to an ionic liquid upon contact with a selected trigger, e.g., contact with CO2, is described. In preferred embodiments, the ionic solvent is readily converted back to the nonionic liquid mixture. The nonionic liquid mixture includes an amidine or guanidine or both, and water, alcohol, or a combination thereof. Single component amine solvents that reversibly convert between ionic and non-ionic states are also described. Some embodiments require increased pressure to convert; others convert at 1 atmosphere. |
FILED | Tuesday, March 13, 2007 |
APPL NO | 11/717172 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 564/238 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982194 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Haw Yang (Moraga, California); Hu Cang (Berkeley, California); Cangshan Xu (Berkeley, California); Chung M. Wong (San Gabriel, California) |
ABSTRACT | A system that can maintain and track the position of a single nanoparticle in three dimensions for a prolonged period has been disclosed. The system allows for continuously imaging the particle to observe any interactions it may have. The system also enables the acquisition of real-time sequential spectroscopic information from the particle. The apparatus holds great promise in performing single molecule spectroscopy and imaging on a non-stationary target. |
FILED | Monday, June 23, 2008 |
APPL NO | 12/144514 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/492.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982296 | Nuzzo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Ralph G. Nuzzo (Champaign, Illinois); John A. Rogers (Champaign, Illinois); Etienne Menard (Durham, North Carolina); Keon Jae Lee (Daejeon, South Korea); Dahl-Young Khang (Urbana, Illinois); Yugang Sun (Champaign, Illinois); Matthew Meitl (Raleigh, North Carolina); Zhengtao Zhu (Urbana, Illinois) |
ABSTRACT | The invention provides methods and devices for fabricating printable semiconductor elements and assembling printable semiconductor elements onto substrate surfaces. Methods, devices and device components of the present invention are capable of generating a wide range of flexible electronic and optoelectronic devices and arrays of devices on substrates comprising polymeric materials. The present invention also provides stretchable semiconductor structures and stretchable electronic devices capable of good performance in stretched configurations. |
FILED | Tuesday, September 22, 2009 |
APPL NO | 12/564566 |
ART UNIT | 2829 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/679 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982370 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Zhong L. Wang (Marietta, Georgia); Xudong Wang (Atlanta, Georgia); Yong Qin (Atlanta, Georgia); Rusen Yang (Atlanta, Georgia) |
ABSTRACT | A small scale electrical generator includes an elongated substrate and a first piezoelectric fine wire. The first piezoelectric fine wire is disposed along a surface of the substrate. The first piezoelectric fine wire has a first end and a spaced-apart second end. A first conductive contact secures the first end of the fine wire to a first portion of the substrate and a second conductive contact secures the second end of the fine wire to a second portion of the substrate. A fabric made of interwoven strands that includes fibers from which piezoelectric nanowires extend radially therefrom and conductive nanostructures extend therefrom is configured to generate electricity. |
FILED | Friday, September 12, 2008 |
APPL NO | 12/209310 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/339 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983517 | Watts et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Michael R. Watts (Albuquerque, New Mexico); Douglas C. Trotter (Albuquerque, New Mexico); Ralph W. Young (Albuquerque, New Mexico); Gregory N. Nielson (Albuquerque, New Mexico) |
ABSTRACT | Optical ring resonator devices are disclosed that can be used for optical filtering, modulation or switching, or for use as photodetectors or sensors. These devices can be formed as microdisk ring resonators, or as open-ring resonators with an optical waveguide having a width that varies adiabatically. Electrical and mechanical connections to the open-ring resonators are made near a maximum width of the optical waveguide to minimize losses and thereby provide a high resonator Q. The ring resonators can be tuned using an integral electrical heater, or an integral semiconductor junction. |
FILED | Thursday, October 09, 2008 |
APPL NO | 12/248679 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/32 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983799 | Bose et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Sumit Bose (Niskayuna, New York); Alfredo Sebastian Achilles (Bavaria, Germany); Yan Liu (Ballston Lake, New York); Emad Ezzat Ahmed (Munich, Germany); Luis Jose Garces (Niskayuna, New York) |
ABSTRACT | A system for controlling a microgrid includes microgrid assets and a tieline for coupling the microgrid to a bulk grid; and a tieline controller coupled to the tieline. At least one of the microgrid assets comprises a different type of asset than another one of the microgrid assets. The tieline controller is configured for providing tieline control signals to adjust active and reactive power in respective microgrid assets in response to commands from the bulk grid operating entity, microgrid system conditions, bulk grid conditions, or combinations thereof. |
FILED | Friday, December 15, 2006 |
APPL NO | 11/611505 |
ART UNIT | 2123 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Generic control systems or specific applications 7/297 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983887 | Agarwal |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Pratul Kumar Agarwal (Knoxville, Tennessee) |
ABSTRACT | The present invention provides a method utilizing primary amino acid sequence of a protein, energy minimization, molecular dynamics and protein vibrational modes to predict three-dimensional structure of a protein. The present invention also determines possible intermediates in the protein folding pathway. The present invention has important applications to the design of novel drugs as well as protein engineering. The present invention predicts the three-dimensional structure of a protein independent of size of the protein, overcoming a significant limitation in the prior art. |
FILED | Friday, April 27, 2007 |
APPL NO | 11/796418 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/11 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07984448 | Almasi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Gheorghe Almasi (Ardsley, New York); Gabor Dozsa (Ardsley, New York); Sameer Kumar (White Plains, New York) |
ABSTRACT | A system and method for supporting collective communications on a plurality of processors that use different parallel programming paradigms, in one aspect, may comprise a schedule defining one or more tasks in a collective operation, an executor that executes the task, a multisend module to perform one or more data transfer functions associated with the tasks, and a connection manager that controls one or more connections and identifies an available connection. The multisend module uses the available connection in performing the one or more data transfer functions. A plurality of processors that use different parallel programming paradigms can use a common implementation of the schedule module, the executor module, the connection manager and the multisend module via a language adaptor specific to a parallel programming paradigm implemented on a processor. |
FILED | Tuesday, June 26, 2007 |
APPL NO | 11/768669 |
ART UNIT | 2196 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07984450 | Almasi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Gheorghe Almasi (Ardsley, New York); Charles J. Archer (Rochester, Minnesota) |
ABSTRACT | Methods, apparatus, and products are disclosed for dispatching packets on a global combining network of a parallel computer comprising a plurality of nodes connected for data communications using the network capable of performing collective operations and point to point operations that include: receiving, by an origin system messaging module on an origin node from an origin application messaging module on the origin node, a storage identifier and an operation identifier, the storage identifier specifying storage containing an application message for transmission to a target node, and the operation identifier specifying a message passing operation; packetizing, by the origin system messaging module, the application message into network packets for transmission to the target node, each network packet specifying the operation identifier and an operation type for the message passing operation specified by the operation identifier; and transmitting, by the origin system messaging module, the network packets to the target node. |
FILED | Wednesday, November 28, 2007 |
APPL NO | 11/946136 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 07980953 | von Ahn Arellano |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Luis von Ahn Arellano (Pittsburgh, Pennsylvania) |
ABSTRACT | A methodology to determine the contents of an image uses an online game that is played by a large number of people at once. Each player may be randomly assigned a partner to form a pair. Partners do not know each other's identity and cannot communicate with one another. Players cannot see what their partners are typing, and the only thing the two partners have in common is an image that they can both see. One object of the game is to have each player type exactly what his or her partner is typing or has already typed. Once both players type the same string of words or letters, they receive a new image (the players are not required to type the string at the same time). The string upon which the two players agree is used as a label for that image. When trying to agree on a word, players may not be able to type certain specific strings of characters or “forbidden words”. When humans play the electronic game (online or over the Internet), they help computers determine the contents of images. If played by a large number of people, this game could provide a resource capable of classifying a vast portion of images on the World Wide Web. Because of the rules governing abstracts, this abstract should not be used to construe the claims. |
FILED | Thursday, June 24, 2004 |
APPL NO | 10/875913 |
ART UNIT | 3718 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Amusement devices: Games 463/42 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981328 | Kahn et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); The Trustees of Princeton Univeristy (Princeton, New Jersey) |
INVENTOR(S) | Antoine Kahn (Princeton, New Jersey); Calvin Chan (South Brunswick, New Jersey); Stephen Barlow (Atlanta, Georgia); Seth Marder (Atlanta, Georgia) |
ABSTRACT | Electron transport material and methods of N-type doping the same are provided. |
FILED | Friday, June 22, 2007 |
APPL NO | 11/766904 |
ART UNIT | 2823 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Compositions 252/519.210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981353 | Mitchell et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Stuart B. Mitchell (Lake Forest Park, Washington); Joan E. Sanders (Sammamish, Washington) |
ABSTRACT | An electrospinning apparatus and methodology is described that produces medical devices, such as scaffolds that induce the formation of a natural fibrous structure (primarily collagen and elastin) in a tissue-engineered medical device. The apparatus uses collection surfaces designed to manipulate or change the electrostatic field so that the electrospun fibers are arranged in desirable patterns that are similar to or mimic the fibrillar structure of an animal tissue. The manipulation results in fibers that are preferentially oriented in a predefined pattern. In addition, the interfiber space between the fibers and the fiber diameter are consistently within a predefined range. Using these techniques in conjunction with controlling polymer properties enables the production of a scaffold that has the structural and mechanical characteristics similar to the native tissue. |
FILED | Tuesday, December 12, 2006 |
APPL NO | 11/609774 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/465 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981392 | Kouvetakis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Arizona Board of Regents, a body corporate of the state of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter, III (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-XSiHX, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HXSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HXSi(OSO2CF3)4-x or HXSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
FILED | Friday, December 31, 2004 |
APPL NO | 11/662722 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981417 | Shusta et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Eric V. Shusta (Madison, Wisconsin); Xin Xiang Wang (Gaithersburg, Maryland); Yongku Peter Cho (Madison, Wisconsin) |
ABSTRACT | This invention provides antibodies that bind brain endothelial cell receptors resulting in endocytosis/transcytosis of the receptor and bound ligands. In some embodiments, the ligand comprises the antibody in combination with a pharmaceutically active compound and the antibody directs delivery of the compound across the blood brain barrier (BBB). The invention also provides methods of identifying endothelial cell specific antibodies by panning the library against cultured cell monolayers. The invention further allows for identifying endothelial cell receptors that bind the antibody thereby providing target receptors against which to isolate further cognate ligands and their associated transport systems and by which to identify transcytosis transporters targeted by the antibodies. |
FILED | Monday, August 03, 2009 |
APPL NO | 12/540897 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/134.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981695 | Schultz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Sheldon Schultz (La Jolla, California); David A. Schultz (La Jolla, California); David R. Smith (La Jolla, California); Jack J. Mock (Del Mar, California); Thomas J. Silva (Golden, Colorado) |
ABSTRACT | A method and apparatus for interrogating a target having a plurality of plasmon resonant particles (PREs) distributed in the target are disclosed. In the method, a field containing the target is illuminated, and one or more spectral emission characteristics of the light-scattering particles in the field are detected. From this data, an image of positions and spectral characteristic values in the field is constructed, allowing PREs with a selected spectral signature to be discriminated from other light-scattering entities, to provide information about the field. Also disclosed are a novel PRE composition for use in practicing the method, and a variety of diagnostic applications of the method. |
FILED | Thursday, March 05, 2009 |
APPL NO | 12/398180 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/525 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981774 | Grier et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | David G. Grier (New York, New York); Yael Roichman (New York, New York); Weining Man (Princeton, New Jersey); Paul Michael Chaikin (Pennington, New Jersey); Paul Joseph Steinhardt (Princeton, New Jersey) |
ABSTRACT | A method and system for assembling a quasicrystalline heterostructure. A plurality of particles is provided with desirable predetermined character. The particles are suspended in a medium, and holographic optical traps are used to position the particles in a way to achieve an arrangement which provides a desired property. |
FILED | Friday, July 07, 2006 |
APPL NO | 11/483021 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/479 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982039 | Marks et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Michael R. Wasielewski (Glenview, Illinois); Antonio Facchetti (Chicago, Illinois); Michael J. Ahrens (Evanston, Illinois); Brooks A. Jones (Evanston, Illinois); Myung-Han Yoon (Evanston, Illinois) |
ABSTRACT | Mono- and diimide perylene and naphthalene compounds, N- and/or core-substituted with electron-withdrawing groups, for use in the fabrication of various device structures. |
FILED | Tuesday, December 29, 2009 |
APPL NO | 12/648484 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/38 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982070 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Lloyd M. Smith (Madison, Wisconsin); Michael R. Shortreed (Portage, Wisconsin); Brian L. Frey (Madison, Wisconsin); Margaret F. Phillips (Madison, Wisconsin); Joshua J. Coon (Middleton, Wisconsin); Shane M. Lamos (Winooski, Vermont); Casey J. Krusemark (Woodside, California); Peter J. Belshaw (Madison, Wisconsin); Madhusudan Patel (Somerset, New Jersey); Neil L. Kelleher (Urbana, Illinois) |
ABSTRACT | Relative quantification of metabolites by Electrospray Ionization Mass Spectrometry (ESI-MS) requiring a mechanism for simultaneous analysis of multiple analytes in two or more samples. Labeling reagents that are reactive to particular compound classes and differ only in their isotopic kit facilitating relative quantification and providing tangible evidence for the existence of specific functional groups. Heavy and light isotopic forms of methylacetimidate were synthesized and used as labeling reagents for quantification of amine-containing molecules, such as biological samples. Heavy and light isotopic forms of formaldehyde and cholamine were also synthesized and used independently as labeling reagents for quantification of amine-containing and carboxylic acid-containing molecules, such as found in biological samples. Advantageously, the labeled end-products are positively charged under normal acidic conditions involving conventional Liquid Chromatography Mass Spectrometry (LC/MS) applications. Labeled primary and secondary amine and carboxylic acid end-products also generated higher signals concerning mass-spectra than pre-cursor molecules and improved sensitivity. Improved accuracy concerning relative quantification was achieved by mixing heavy and light labeled Arabidopsis extracts in different ratios. Labeling strategy was further employed to ascertain differences in the amounts of amine-containing metabolites for two strains of Arabidopsis seeds. |
FILED | Wednesday, March 21, 2007 |
APPL NO | 11/726307 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 564/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982130 | Forrest et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Michael S. Arnold (Ann Arbor, Michigan); Jeramy D. Zimmerman (Ann Arbor, Michigan) |
ABSTRACT | A photovoltaic device includes a photoactive region disposed between and electrically connected to two electrodes where the photoactive region includes photoactive polymer-wrapped carbon nanotubes that create excitons upon absorption of light in the range of about 400 nm to 1400 nm. |
FILED | Friday, January 09, 2009 |
APPL NO | 12/351378 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/263 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982370 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Zhong L. Wang (Marietta, Georgia); Xudong Wang (Atlanta, Georgia); Yong Qin (Atlanta, Georgia); Rusen Yang (Atlanta, Georgia) |
ABSTRACT | A small scale electrical generator includes an elongated substrate and a first piezoelectric fine wire. The first piezoelectric fine wire is disposed along a surface of the substrate. The first piezoelectric fine wire has a first end and a spaced-apart second end. A first conductive contact secures the first end of the fine wire to a first portion of the substrate and a second conductive contact secures the second end of the fine wire to a second portion of the substrate. A fabric made of interwoven strands that includes fibers from which piezoelectric nanowires extend radially therefrom and conductive nanostructures extend therefrom is configured to generate electricity. |
FILED | Friday, September 12, 2008 |
APPL NO | 12/209310 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/339 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982375 | Tan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Xiaobo Tan (East Lansing, Michigan); Ning Xi (Okemos, Michigan); Zheng Chen (Charlottesville, Virginia); Yantao Shen (Reno, Nevada) |
ABSTRACT | An integrated sensory actuator (10) which uses an electroactive polymer is provided. The sensory actuator is comprised of an actuating member (12) made of an ionic polymer-metal composite; a sensing member (14) made of a piezoelectric material; and an insulating member (16) interposed between the actuating member and the sensing member. The sensory actuator may further include a compensation circuit adapted to receive a sensed signal from the sensing member and an actuation signal from the actuating member and compensate the sensed signal for feedthrough coupling between the actuating member and the sensing member. |
FILED | Wednesday, December 12, 2007 |
APPL NO | 12/519099 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/800 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983074 | Zhu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Frank Qing Zhu (San Jose, California); Chia-Ling Chien (Cockeysville, Maryland) |
ABSTRACT | Featured is a magnetic ring structure including at least a vortex magnetic state such as symmetrically and asymmetrically shaped nanorings (FIG. 7C), having small diameters (e.g., on the order of 100 run). In particular embodiments, the width and thickness of the maxima and minima thereof are located on opposite sides of the nanoring. Also featured are methods for fabricating such symmetrically and asymmetrically shaped nanorings (FIG. 1). Also featured are methods for controlling the reversal process so as to thereby create vortex states in such asymmetric nanorings by controlling the field angle (FIG. 9). |
FILED | Tuesday, March 14, 2006 |
APPL NO | 11/885846 |
ART UNIT | 2827 — Semiconductors/Memory |
CURRENT CPC | Static information storage and retrieval 365/158 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 07980449 | Ding |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | R. Jeffrey Ding (Athens, Alabama) |
ABSTRACT | A welding method and apparatus are provided for forming a weld joint between first and second elements of a workpiece. The method includes heating the first and second elements to form an interface of material in a plasticized or melted state interface between the elements. The interface material is then allowed to cool to a plasticized state if previously in a melted state. The interface material, while in the plasticized state, is then mixed, for example, using a grinding/extruding process, to remove any dendritic-type weld microstructures introduced into the interface material during the heating process. |
FILED | Friday, February 28, 2003 |
APPL NO | 10/385168 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Metal fusion bonding 228/227 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981229 | Hood et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cornerstone Research Group, Inc (Dayton, Ohio) |
INVENTOR(S) | Patrick J. Hood (Bellbrook, Ohio); Sean Garrigan (Beavercreek, Ohio); Frank Auffinger (Hamilton, Ohio) |
ABSTRACT | Patches consisting of transparent or translucent shape memory material can be manufactured so as to affect repair of transparent or translucent parts that have been damaged. These patches can be used to cover cracks and holes or provide additional structural support for the damaged parts. The patches can vary greatly in size and properties depending on the desired application. |
FILED | Friday, December 15, 2006 |
APPL NO | 11/611184 |
ART UNIT | 1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/94 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982353 | Wilson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Andrew Wilson (Allison Park, Pennsylvania); Andrew Punnoose (Ashburn, Virginia); Katherine Strausser (Houston, Texas); Neil Parikh (North Brunswick, New Jersey) |
ABSTRACT | A directed flux motor described utilizes the directed magnetic flux of at least one magnet through ferrous material to drive different planetary gear sets to achieve capabilities in six actuated shafts that are grouped three to a side of the motor. The flux motor also utilizes an interwoven magnet configuration which reduces the overall size of the motor. The motor allows for simple changes to modify the torque to speed ratio of the gearing contained within the motor as well as simple configurations for any number of output shafts up to six. The changes allow for improved manufacturability and reliability within the design. |
FILED | Thursday, September 23, 2010 |
APPL NO | 12/888816 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/181 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982439 | Trainor et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | TPL, Inc. (Albuquerque, New Mexico) |
INVENTOR(S) | John T. Trainor (Albuquerque, New Mexico); Patrick Franz Fleig (Albuquerque, New Mexico); Charles D. E. Lakeman (Albuquerque, New Mexico); Jenniffer Leigh DeGreeff (Albuquerque, New Mexico) |
ABSTRACT | A device and method for harvesting, generating, storing, and delivering energy to a load, particularly for remote or inaccessible applications. The device preferably comprises one or more energy sources, at least one supercapacitor, at least one rechargeable battery, and a controller. The charging of the energy storage devices and the delivery of power to the load is preferably dynamically varied to maximize efficiency. A low power consumption charge pump circuit is preferably employed to collect power from low power energy sources while also enabling the delivery of higher voltage power to the load. The charging voltage is preferably programmable, enabling one device to be used for a wide range of specific applications. |
FILED | Thursday, April 01, 2010 |
APPL NO | 12/752593 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/166 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982777 | Prechtl et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Axis Engineering Technologies, Inc. (Devens, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Eric F. Prechtl (Groton, Massachusetts); Raymond J. Sedwick (Somerville, Massachusetts); Eric M. Jonas (Cambridge, Massachusetts) |
ABSTRACT | A stereoscopic imaging system incorporates a plurality of imaging devices or cameras to generate a high resolution, wide field of view image database from which images can be combined in real time to provide wide field of view or panoramic or omni-directional still or video images. |
FILED | Friday, April 07, 2006 |
APPL NO | 11/400758 |
ART UNIT | 2622 — Selective Visual Display Systems |
CURRENT CPC | Television 348/211.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982861 | Abshire et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | James B. Abshire (Clarksville, Maryland); Xiaoli Sun (Clarksville, Maryland) |
ABSTRACT | A method for measuring time delay and distance may include providing an electromagnetic radiation carrier frequency and modulating one or more of amplitude, phase, frequency, polarization, and pointing angle of the carrier frequency with a return to zero (RZ) pseudo random noise (PN) code. The RZ PN code may have a constant bit period and a pulse duration that is less than the bit period. A receiver may detect the electromagnetic radiation and calculate the scattering profile versus time (or range) by computing a cross correlation function between the recorded received signal and a three-state RZ PN code kernel in the receiver. The method also may be used for pulse delay time (i.e., PPM) communications. |
FILED | Thursday, July 31, 2008 |
APPL NO | 12/183820 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Optics: Measuring and testing 356/5.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 07981495 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Invensys Systems, Inc. (Foxboro, Massachusetts); University of Massachusetts (Worcester, Massachusetts) |
INVENTOR(S) | Yong K. Kim (North Dartmouth, Massachusetts); Armand F. Lewis (Mattapoisett, Massachusetts); John M. Rice (Portsmouth, Rhode Island) |
ABSTRACT | Fiber based z-directional reinforced composites having enhanced inter-laminar strength, impact toughness, transmission properties (electrical and thermal conduction) and coefficient of thermal expansion are provided. The composites include at least two substrates separated by a reinforcement zone that includes a plurality of fibers disposed in a binder resin. At least some, and in one embodiment, a majority, of the fibers are oriented so as to be substantially perpendicular to the substrates. Multi-layered composites having more than two substrate layers can also be formed. Methods for forming such composites are also provided. |
FILED | Wednesday, October 31, 2007 |
APPL NO | 11/931416 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Stock material or miscellaneous articles 428/86 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981660 | Gerngross |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Glycofi, Inc. (Lebanon, New Hampshire) |
INVENTOR(S) | Tillman U. Gerngross (Hanover, New Hampshire) |
ABSTRACT | Cell lines having genetically modified glycosylation pathways that allow them to carry out a sequence of enzymatic reactions, which mimic the processing of glycoproteins in humans, have been developed. Recombinant proteins expressed in these engineered hosts yield glycoproteins more similar, if not substantially identical, to their human counterparts. The lower eukaryotes, which ordinarily produce high-mannose containing N-glycans, including unicellular and multicellular fungi are modified to produce N-glycans such as Man5GlcNAc2 or other structures along human glycosylation pathways. This is achieved using a combination of engineering and/or selection of strains which: do not express certain enzymes which create the undesirable complex structures characteristic of the fungal glycoproteins, which express exogenous enzymes selected either to have optimal activity under the conditions present in the fungi where activity is desired, or which are targeted to an organelle where optimal activity is achieved, and combinations thereof wherein the genetically engineered eukaryote expresses multiple exogenous enzymes required to produce “human-like” glycoproteins. |
FILED | Thursday, August 27, 2009 |
APPL NO | 12/549062 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/254.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981696 | Moreland et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia) |
INVENTOR(S) | John Moreland (Louisville, Colorado); Elizabeth Mirowski (Boulder, Colorado); Stephen E. Russek (Louisville, Colorado) |
ABSTRACT | Arrays of spin-valve elements that can be selectively activated to trap, hold, manipulate and release magnetically tagged biological and chemical particles, including molecules and polymers. The spin-valve elements that can be selectively activated and deactivated by applying a momentary applied magnetic field thereto. The spin valve element array can be used for selectively sorting and transporting magnetic particles one particle at a time within the array. As the magnetically tagged particles are held by the spin-valve elements, application of an auxiliary magnetic field can be used to apply tension or torsion to the held particles or to move, e.g. rotate, the trapped particles. The arrays of spin-valve elements can be used in a variety of applications including drug screening, nucleic acid sequencing, structural control and analysis of RNA/DNA and protiens, medical diagnosis, and magnetic particle susceptibility and size homogenization for other medical applications. |
FILED | Friday, February 18, 2005 |
APPL NO | 11/061461 |
ART UNIT | 3768 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/526 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983448 | da Vitoria Lobo et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
INVENTOR(S) | Niels da Vitoria Lobo (Winter Park, Florida); Mehmet B Caglar (Oviedo, Florida) |
ABSTRACT | Apparatus, methods, systems and devices for identifying and tracking a human hand in a video. The steps for identifying the hand includes detecting parallel lines (bars), detecting curved fingertips (curves), grouping the detected parallel lines and curved fingertips according to a parallel line decision tree and a curved fingertip decision tree, respectively, and merging the parallel line group and the curved fingertip group to identify candidate hands. |
FILED | Thursday, May 24, 2007 |
APPL NO | 11/753233 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 07981432 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Shrewsbury, Massachusetts) |
INVENTOR(S) | Bal Ram Singh (Dartmouth, Massachusetts); Zhong Zhang (New Bedford, Massachusetts) |
ABSTRACT | The invention features a polypeptide complex synthesized by bacteria of the genus Clostridia that contains the serotype E botulinum neurotoxin and five neurotoxin associated polypeptides having molecular weights of about 118, 80, 65, 40, and 18 kDa, respectively. The complex is useful in the treatment of diseases or conditions that are caused by excessive release of acetylcholine from presynaptic nerve terminals. |
FILED | Tuesday, October 07, 2008 |
APPL NO | 12/247124 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/239.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981438 | Lan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Que Lan (Madison, Wisconsin); Min-Sik Kim (Madison, Wisconsin) |
ABSTRACT | Methods of killing mosquito larvae and controlling an adult mosquito population by using α-mangostin, 3,6,8-yrihydroxy-2-methoxy-1,7-bis(3-methylbut-2-enyl)xanthen-9-one, or a salt, solute, hydrate or solvate thereof. Mosquito larvae are killed by contacting a lethal dose of α-mangostin with mosquito larvae. Adult mosquito populations are controlled by treating a mosquito larvae population with a lethal dose of α-mangostin. |
FILED | Friday, May 30, 2008 |
APPL NO | 12/130134 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/405 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07982003 | Donovan |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | David M. Donovan (Baltimore, Maryland) |
ABSTRACT | The invention concerns a nucleic acid encoding a recombinant bifunctional fusion peptidoglycan hydrolase protein formed from a nucleic acid encoding a peptidoglycan hydrolase module and a nucleic acid encoding a second peptidoglycan hydrolase module. The fusion, dual (or multiples thereof) peptidoglycan hydrolase modules can be used to treat disease caused by the bacteria for which the individual modules of the fusion protein are specific. |
FILED | Monday, July 06, 2009 |
APPL NO | 12/498171 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
US 07981392 | Kouvetakis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Arizona Board of Regents, a body corporate of the state of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter, III (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-XSiHX, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HXSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HXSi(OSO2CF3)4-x or HXSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
FILED | Friday, December 31, 2004 |
APPL NO | 11/662722 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983890 | Bliss et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Nadya Travinin Bliss (Cambridge, Massachusetts); Henry Hoffman (Somerville, Massachusetts) |
ABSTRACT | A method, apparatus and computer program product for mapping and executing an application on a multi-processor system is presented. At least one array to be considered for distribution among processors of said multi-processor system is indicated. The application is mapped according to a performance model associated with benchmark performance data of a parallel library on a parallel computer architecture. Then either the application is executed on the multi-processor system, or the application is simulated using a specified machine model for a multiprocessor system. Feedback information is then provided to influence architecture parameters for a multiprocessor system. |
FILED | Monday, June 16, 2008 |
APPL NO | 12/139802 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 07983396 | Bertozzi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Passport Systems, Inc. (Billerica, Massachusetts) |
INVENTOR(S) | William Bertozzi (Lexington, Massachusetts); Michael Donovan (Dover, Massachusetts); Alexei Klimenko (Tyngsboro, Massachusetts); Stephen E. Korbly (Acton, Massachusetts); William Park (Somerville, Massachusetts) |
ABSTRACT | Methods and systems for generating bremsstrahlung with enhanced photon flux in a narrow cone at forward angles utilize a thin target of a high-Z material such as gold as radiator, supported on a tube of a low-Z material such as titanium, which tube contains a circulating fluid such as water which acts as a coolant and also may absorb the incident electron beam. |
FILED | Thursday, May 15, 2008 |
APPL NO | 12/121515 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/141 |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 07982751 | Stotts, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The University of North Carolina (Chapel Hill, North Carolina) |
INVENTOR(S) | Paul David Stotts, Jr. (Pittsboro, North Carolina); Jason McColm Smith (Raleigh, North Carolina) |
ABSTRACT | The methods described herein for controlling a computer using a video image and for combining the video image with a computer desktop may be implemented in hardware, software, firmware, or any combination thereof. In one exemplary implementation, the methods described herein may be implemented as computer executable instructions embodied in a computer readable medium. Exemplary computer-readable media suitable for use with the implementations described herein include disk storage devices and chip memory devices. |
FILED | Friday, July 09, 2004 |
APPL NO | 10/562240 |
ART UNIT | 2628 — Selective Visual Display Systems |
CURRENT CPC | Computer graphics processing and selective visual display systems 345/633 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 07984293 | Winslow |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | L3 Communications Corporation (New York, New York) |
INVENTOR(S) | Richard Norman Winslow (Wilmington, Delaware) |
ABSTRACT | A Personal Computer Memory Card International Association (PCMCIA) card may establish, via a non-secure network, a secure communications channel between a computer and a secure network. The non-secure network may define a first address space. The secure network may define a second address space. The PCMCIA card may include a cryptography module, a network adapter, and/or a processor. The cryptography module may provide Type 1 cryptography of data communicated between the computer and the secure network. The network adapter may be in communication with the non-secure network and may be associated with a first network address from the first address space. The processor may be in communication with the secure network via the cryptography module and the network adapter. The processor may identify a second network address for the computer from the second address space and may communicate the second network address to the computer, for example via dynamic host control protocol (DHCP). |
FILED | Friday, July 13, 2007 |
APPL NO | 11/777549 |
ART UNIT | 2431 — Cryptography and Security |
CURRENT CPC | Electrical computers and digital processing systems: Support 713/162 |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 07982002 | Reed et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Burnham Institute for Medical Research (La Jolla, California) |
INVENTOR(S) | John C. Reed (La Jolla, California); Shu-ichi Matsuzawa (La Jolla, California) |
ABSTRACT | In accordance with the present invention, there are provided novel Siah-Mediated-Degradation-Proteins (SMDPS) and/or SCF-Complex Proteins (SCPs). Nucleic acid sequences encoding such proteins and assays employing same are also disclosed. The invention SMDPs and/or SCPs can be employed in a variety of ways, for example, for the production of anti-SMDP and/or SCP antibodies thereto, in therapeutic compositions, and methods employing such proteins and/or antibodies for drug screening, functional genomics and other applications. Also provided are transgenic non-human mammals that express the invention protein. Also provided are compositions and methods for targeting the destruction of selected polypeptides in eukaryotic cells based on the ubiquitin-independent mechanism by which ornithine decarboxylase is degraded by the 26S proteasome. |
FILED | Wednesday, March 04, 2009 |
APPL NO | 12/397468 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 07981660 | Gerngross |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Glycofi, Inc. (Lebanon, New Hampshire) |
INVENTOR(S) | Tillman U. Gerngross (Hanover, New Hampshire) |
ABSTRACT | Cell lines having genetically modified glycosylation pathways that allow them to carry out a sequence of enzymatic reactions, which mimic the processing of glycoproteins in humans, have been developed. Recombinant proteins expressed in these engineered hosts yield glycoproteins more similar, if not substantially identical, to their human counterparts. The lower eukaryotes, which ordinarily produce high-mannose containing N-glycans, including unicellular and multicellular fungi are modified to produce N-glycans such as Man5GlcNAc2 or other structures along human glycosylation pathways. This is achieved using a combination of engineering and/or selection of strains which: do not express certain enzymes which create the undesirable complex structures characteristic of the fungal glycoproteins, which express exogenous enzymes selected either to have optimal activity under the conditions present in the fungi where activity is desired, or which are targeted to an organelle where optimal activity is achieved, and combinations thereof wherein the genetically engineered eukaryote expresses multiple exogenous enzymes required to produce “human-like” glycoproteins. |
FILED | Thursday, August 27, 2009 |
APPL NO | 12/549062 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/254.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 07981392 | Kouvetakis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Arizona Board of Regents, a body corporate of the state of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter, III (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-XSiHX, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HXSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HXSi(OSO2CF3)4-x or HXSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
FILED | Friday, December 31, 2004 |
APPL NO | 11/662722 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 07984289 | Orbke et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Wayne H. Orbke (Germantown, Tennessee); Samuel R. Tremaine (Memphis, Tennessee) |
ABSTRACT | Registration information is sent form a customer to a registration system over a network. The registration system creates an electronic account for the customer and facilitates the validation of the customer's identity. When the customer's identity is validated, the registration system activates the electronic account. The electronic account includes a unique electronic account number, a physical address of the customer, and an electronic address of the customer. |
FILED | Wednesday, July 13, 2005 |
APPL NO | 11/179546 |
ART UNIT | 2435 — Cryptography and Security |
CURRENT CPC | Electrical computers and digital processing systems: Support 713/155 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 07981596 | Thatte et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Department of Veteran's Affairs (Washington, District of Columbia) |
INVENTOR(S) | Hemant Thatte (Medfield, Massachusetts); Kunda Biswas (Boston, Massachusetts); Shukri Khuri (Westwood, Massachusetts); Thomas Michel (Lincoln, Massachusetts) |
ABSTRACT | The present invention provides for compositions and methods for the preservation of tissues and organs ex vivo and in situ. In addition, the present invention provides for kits that may be used in the preparation of the solutions of the present invention. |
FILED | Friday, August 25, 2006 |
APPL NO | 11/510068 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/1.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07981675 | Amar et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Salomon Amar (Brookline, Massachusetts); Xiaoren Tang (Winchester, Massachusetts) |
ABSTRACT | The invention provides molecules containing nucleic acid sequences for fragments of LPS-induced TNF-α factor (LITAF) and vectors containing these sequences. Also provided are molecules that contain the peptide sequence SQTWREPGAAGSPFHL (SEQ ID NO: 5), or homologs thereof. Such molecules may be useful in the treatment of diseases that relate to the expression of TNF-α, where treatment involves the modulation of this expression. The invention also provides methods for identifying compounds that inhibit or enhance the transcription of TNF-α. |
FILED | Wednesday, February 20, 2008 |
APPL NO | 12/033998 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07983850 | Shaughnessy et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
INVENTOR(S) | John D. Shaughnessy (Little Rock, Arkansas); Bart Barlogie (Little Rock, Arkansas); Fenghuang Zhan (Little Rock, Arkansas) |
ABSTRACT | Provided herein is a method for gene expression profiling multiple myeloma patients into distinct subgroups via DNA hybridization and hierarchical clustering analysis of the hybridization data where the results may further be used to identify therapeutic gene targets. Also provided is a method for controlling bone loss in an individual via pharmacological inhibitors of DKK1 protein. In addition provided herein is a method for diagnosing multiple myeloma using a 15-gene model that classifies myeloma into groups 1-7. |
FILED | Friday, February 01, 2008 |
APPL NO | 12/012302 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 07984052 | Griffith et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Frank P. Griffith (Bellevue, Nebraska); Gregory P. Armendariz (Papillon, Nebraska); Robert W. Bowne (Papillon, Nebraska); Lee R. Venable (Lavista, Nebraska) |
ABSTRACT | According to one embodiment of the disclosure, a computing system generally includes a geographical information system that is coupled to a data record interface. The data record interface is operable to receive a data record having a data type that is different from a second data type used by the geographical information system. The data record may then determine the data type of the data record and accordingly invoke a particular plug-in that is operable to convert the first data type to the second data type. The data record interface may then transmit the converted data record to the geographical information system. |
FILED | Tuesday, June 12, 2007 |
APPL NO | 11/761907 |
ART UNIT | 2166 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/736 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 19, 2011.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2011/fedinvent-patents-20110719.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page