FedInvent™ Patents

Patent Details for Tuesday, August 23, 2011 

This page was updated on Monday, March 27, 2023 at 02:03 AM GMT

Department of Health and Human Services (HHS) 

US 08001876 Tabb et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) SAIC-Frederick, Inc. (Frederick, Maryland)
INVENTOR(S) Brian Carroll Tabb (Cumberland, Maryland);  Keith Rogers (Singapore, Singapore)
ABSTRACT Systems and methods described herein for aligning a block in a microtome attempt to save time, money, and the sample by aligning a block in any rotary or cryostat microtome. One such device for aligning a block in a microtome has a knife holder component removably attached to a knife holder of the microtome and a pin alignment component extending vertically from the knife holder component in a direction substantially parallel to the block. The pin alignment component has a plurality of front pins extending from a front surface of the pin alignment component configured to slide in response to an angle of the block and a plurality of rear pins extending from a rear surface of the pin alignment component and coupled to the front pins. The rear pins are configured to indicate the extension of the front pins from the pin alignment component.
FILED Wednesday, May 14, 2008
APPL NO 12/153110
ART UNIT 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Cutting
083/522.150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002933 Unger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Marc A. Unger (South San Francisco, California);  Hou-Pu Chou (Pasadena, California);  Todd A. Thorsen (Pasadena, California);  Axel Scherer (Laguna Beach, California);  Stephen R. Quake (San Marino, California)
ABSTRACT A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.
FILED Friday, November 02, 2007
APPL NO 11/934235
ART UNIT 1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/242
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US 08003078 Lanza et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Barnes-Jewish Hospital (St. Louis, Missouri)
INVENTOR(S) Gregory M. Lanza (St. Louis, Missouri);  Samuel A. Wickline (St. Louis, Missouri);  Garry E. Kiefer (Richardson, Texas);  Phillip S. Athey (Lake Jackson, Texas)
ABSTRACT MRI contrast agents that employ paramagnetic agents and chemical exchange saturation transfer (paraCEST) and which are coupled to targeted particulate delivery vehicles provide sufficient concentration of the paraCEST contrast agents to obtain useful images of target tissues or organs. In addition, the image contrast may be switched on or off with a presaturation radio frequency pulse, avoiding the necessity obtaining pre-injection and post-injection images.
FILED Thursday, March 29, 2007
APPL NO 11/693647
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.365
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003112 Tai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Howard University (Washington, District of Columbia);  The United States of America as represented by the Secretary, Department of Health and Human Services; National Institutes of Health, Office of Technology Transfer (Washington, District of Columbia)
INVENTOR(S) Stanley Shih-Peng Tai (Rockville, Maryland);  Che-Hung Robert Lee (Silver Spring, Maryland)
ABSTRACT This disclosure relates to vaccine formulations comprising an immunogenic composition for inducing antibodies to both S. pneumoniae and N. meningitides in a subject. In a preferred aspect, the immunogenic composition comprises covalently conjugated recombinant PsaA (“rPsaA”) from S. pneumoniae and capsular polysaccharide from N. meningitidis serogroup C. This disclosure further relates to methods for producing the immunogenic composition as well as methods for their use.
FILED Thursday, April 16, 2009
APPL NO 12/425232
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/197.110
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US 08003113 Narayan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Opendra Narayan (Lenexa, Kansas);  Zhenqian Liu (Lenexa, Kansas)
ABSTRACT The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for used as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3′ LTR.
FILED Monday, February 09, 2009
APPL NO 12/368151
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/208.100
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US 08003129 Hoffman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington);  Univeristy of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Allan S. Hoffman (Seattle, Washington);  Patrick Stayton (Seattle, Washington);  Oliver W. Press (Seattle, Washington);  Niren Murthy (Atlanta, Georgia);  Chantal Lackey Reed (Del Mar, California);  Lawrence A. Crum (Bellevue, Washington);  Pierre D. Mourad (Seattle, Washington);  Tyrone M. Porter (Boston, Massachusetts);  David Tirrell (Pasadena, California)
ABSTRACT Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontophoresis, and/or electrophoresis can also be used with the disrupting agents.
FILED Friday, April 18, 2008
APPL NO 12/105983
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/501
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US 08003131 Badylak
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Stephen F. Badylak (Pittsburgh, Pennsylvania)
ABSTRACT A tissue graft composition comprising liver basement membrane is described. The graft composition can be implanted to replace or induce the repair of damaged or diseased tissues.
FILED Tuesday, January 06, 2009
APPL NO 12/349254
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/553
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US 08003312 Krutzik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Peter O. Krutzik (Los Altos, California);  Garry Nolan (San Francisco, California)
ABSTRACT We describe herein a cell-based multiplexing technique called detectable cell barcoding (DCB). In DCB, each individual sample is labeled with a different DCB signature that distinguishes each sample by one or both of detected intensity or type of detection characteristic. The samples are then combined and analyzed for a detectable characteristic of interest (e.g., presence of an analyte). By employing multiple distinct DCB labels at varying concentrations, one can perform multiplex analyses on up to hundreds or thousands (or more) of cell samples in a single reaction tube. DCB reduces reagent consumption by factors of 100-fold or more, significantly reduces data acquisition times and allows for stringent control sample analysis.
FILED Thursday, February 14, 2008
APPL NO 12/031499
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
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US 08003324 Dudley, Jr.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) U.S. Department of Veterans Affairs (Washington, District of Columbia);  Emory University (Atlanta, Georgia)
INVENTOR(S) Samuel C. Dudley, Jr. (Chicago, Illinois)
ABSTRACT The present invention relates to the use of oxidized nicotinamide adenine dinucleotide (NAD+) or of its reduced form, NADH, as sodium channel modulators. The present invention also relates to the use of compositions containing NAD+ or NADH to treat conditions associated with sodium channel current, such as arrhythmia. NAD+ is found to increase sodium channel current, while NADH is found to decrease sodium channel current. Thus, conditions that are associated with decreased sodium channel current can be treated with NAD+, while conditions that is associated with increased sodium channel current can be treated with NADH.
FILED Friday, October 17, 2008
APPL NO 12/289005
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 08003325 Ansell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Stephen M. Ansell (Rochester, Minnesota);  Anne J. Novak (Oronoco, Minnesota)
ABSTRACT The present invention provides an isolated polynucleotide comprising at least one polymorphic nucleotide sequence, for example, the major alleles of the SNPs described as rs12583006, rs1224141, and rs1248930 and diagnostic assays for detecting the presence of these polymorphism associated with a condition associated with BLyS activity, such as hematological malignancy including B cell malignancies. The diagnostic assays are useful in predicting an individual's likelihood of developing a condition associated with BLyS activity, such as hematological malignancies, and for methods for treating an individual clinically diagnosed with a condition associated with BLyS activity, such as prediction of a patient's likelihood to respond to a specific drug treatment. The invention also provides an array of nucleic acid molecules immobilized on a solid surface, where at least one of the nucleic acid molecules comprises a BLyS polymorphic nucleic acid molecule. The nucleic acid arrays of the invention allow rapid detection of hybridizing nucleic acid-molecules, in a nucleic acid sample from an individual, of a BLyS polymorphism associated with hematological malignancy.
FILED Wednesday, November 26, 2008
APPL NO 12/323861
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003327 Boustany et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Rose-Mary N. Boustany (Durham, North Carolina);  Wei-Xing Guo (Northridge, California);  Andrea Amalfitano (Durham, North Carolina)
ABSTRACT A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore.
FILED Thursday, January 22, 2009
APPL NO 12/357750
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 08003332 Kielian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S) Margaret Kielian (Pelham, New York);  Maofu Liao (San Francisco, California)
ABSTRACT Methods of inhibiting viral infection of a eukaryotic cell by a target virus having a class II virus fusion protein are provided. Also provided are methods of screening a test compound for the ability to inhibit infection by a virus having a class II viral fusion protein. Additionally provided herewith are aqueous-soluble proteins comprising a portion of a class II viral fusion protein comprising a Domain III of the viral fusion protein.
FILED Thursday, May 04, 2006
APPL NO 11/918835
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003342 Brown et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Michael S. Brown (Dallas, Texas);  Joseph L. Goldstein (Dallas, Texas);  Yuval Reiss (Dallas, Texas)
ABSTRACT Disclosed are methods and compositions for the identification of inhibitors of farnesyl protein transferases, enzymes involved in the farnesylation of various cellular proteins, including cancer related ras proteins such as p21ras. One farnesyl protein transferase which is disclosed herein exhibits a molecular weight of between about 70,000 and about 100,000 upon gel exclusion chromatography. The enzyme appears to comprise one or two subunits of approximately 50 kDa each. Methods are disclosed for assay and purification of the enzyme, as well as procedures for using the purified enzyme in screening protocols for the identification of possible anticancer agents which inhibit the enzyme and thereby prevent expression of proteins such as p21ras. Also disclosed is a families of compounds which act either as false substrates for the enzyme or as pure inhibitors and can therefore be employed for inhibition of the enzyme. The most potent inhibitors are ones in which phenylalanine occurs at the third position of a tetrapeptide whose amino terminus is cysteine.
FILED Thursday, April 18, 1991
APPL NO 07/937893
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/15
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US 08003354 Shen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S) Illumina, Inc. (San Diego, California)
INVENTOR(S) Min-Jui Richard Shen (San Diego, California);  Arnold Oliphant (Poway, California);  Scott L. Butler (San Diego, California);  John R. Stuelpnagel (Encinitas, California);  Mark S. Chee (Del Mar, California);  Kenneth M. Kuhn (San Diego, California);  Jian-Bing Fan (San Diego, California)
ABSTRACT The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.
FILED Friday, February 15, 2008
APPL NO 12/032581
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003374 Heeger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alan J. Heeger (Santa Barbara, California);  Chunhai Fan (Shanghai, China PRC);  Kevin Plaxco (Santa Barbara, California)
ABSTRACT A reagentless, reusable bioelectronic DNA, or other oligonucleotide sequence sensor is disclosed. The sensor includes an oligonucleotide (aptamer) probe tagged with a electroactive, redoxable moiety, self-assembled on or near an electrode. This surface-confined oligonucleotide (aptamer) probe structure undergoes hybridization-induced conformational change in the presence of the target which changes the electron-transfer distance between the redoxable moiety and the electrode thereby providing a detectable signal change. In an alternative embodiment, the target can harbor the redoxable moiety.
FILED Friday, July 29, 2005
APPL NO 11/193318
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/287.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003378 Wikswo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) John P. Wikswo (Brentwood, Tennessee);  Franz J. Baudenbacher (Franklin, Tennessee);  Ales Prokop (Nashville, Tennessee);  Eugene LeBoeuf (Franklin, Tennessee);  Chang Y. Chung (Franklin, Tennessee);  David E. Cliffel (Nashville, Tennessee);  Frederick R. Haselton (Nashville, Tennessee);  William H. Hofmeister (Nashville, Tennessee);  Charles P. Lin (Brentwood, Tennessee);  Lisa J. McCawley (Nashville, Tennessee);  Randall S. Reiserer (Nashville, Tennessee);  Mark A. Stremler (Franklin, Tennessee)
ABSTRACT A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel.
FILED Thursday, March 05, 2009
APPL NO 12/398825
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/289.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003384 Matsunami et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Hiroaki Matsunami (Durham, North Carolina);  Momoka Matsunami (Durham, North Carolina);  Yoshiro Ishimaru (Tokyo, Japan)
ABSTRACT The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
FILED Monday, December 07, 2009
APPL NO 12/632299
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
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US 08003388 Neumann
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Nortis, Inc. (Gig Harbor, Washington)
INVENTOR(S) Thomas Neumann (Seattle, Washington)
ABSTRACT A method for creating networks of perfusable microvessels in vitro. A mandrel is drawn through a matrix to form a channel through the matrix. Cells are injected into the channel. The matrix is incubated to allow the cells to attach inside the channel. The channel is perfused to remove unattached cells to create a parent vessel, where the parent vessel includes a perfusable hollow channel lined with cells in the matrix. The parent vessel is induced to create sprouts into the surrounding matrix gel so as to form a microvessel network. The microvessel network is subjected to luminal perfusion through the parent vessel.
FILED Monday, September 24, 2007
APPL NO 11/860471
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/395
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US 08003390 Donohue et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Timothy J. Donohue (Milddleton, Wisconsin);  Jennifer Rachel Anthony (San Lorenzo, California);  Kristin L. Warczak (Franklin, Wisconsin);  Yann Dufour (Madison, Wisconsin);  Heather Green (Madison, Wisconsin)
ABSTRACT The physiological response of a phototroph to singlet oxygen is altered by modulating the interaction between an anti-sigma factor, ChrR, and a sigma factor, σE, or by altering expression of a gene product required for viability in the presence of singlet oxygen.
FILED Tuesday, April 25, 2006
APPL NO 11/410431
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/471
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US 08003404 Rotello et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Vincent Rotello (Belchertown, Massachusetts);  Uwe Bunz (Atlanta, Georgia);  Ronnie Phillips (Atlanta, Georgia);  Oscar Miranda (Amherst, Massachusetts);  Chang-Cheng You (Waltham, Massachusetts)
ABSTRACT Compositions, methods and related apparatus, as can be used for selective pathogen detection and identification.
FILED Monday, November 17, 2008
APPL NO 12/313137
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/172
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US 08003406 Muenke et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Maximilian Muenke (Bala Cynwyd, Pennsylvania);  Mauricio Arcos-Burgos (Rockville, Maryland);  F. Xavier Castellanos (New York, New York)
ABSTRACT The invention provides a method of determining a susceptibility of a subject for development of ADHD. The method comprises obtaining a sample from the subject, analyzing the sample for an ADHD susceptibility haplotype of LPHN3 receptor which is associated with at least one genetic marker selected from the group consisting of rs7678046, rs1901223, rs6813183, and rs1355368, and determining if the subject has a susceptibility to develop ADHD, whereby the presence of the haplotype having one or more of the genetic markers is indicative of a susceptibility to develop ADHD. The invention also provides methods of treating ADHD.
FILED Thursday, September 27, 2007
APPL NO 12/444898
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/504
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US 08003572 Banerjee
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Amit Banerjee (Grosse Pointe, Michigan)
INVENTOR(S) Amit Banerjee (Grosse Pointe, Michigan)
ABSTRACT The present invention provides methods for identifying compounds that selectively bind one or more active sites within an ubiquitin conjugating enzyme. The compounds identified by the methods are useful in the treatment of disorders attributed to dysregulated ubiquitin conjugating enzyme function, specifically in hyperproliferative disorders.
FILED Thursday, December 28, 2006
APPL NO 11/647788
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Combinatorial chemistry technology: Method, library, apparatus
56/8
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US 08003606 Patti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Joslin Diabetes Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Mary Elizabeth Patti (Newton, Massachusetts);  Wanzhu Jin (Brookline, Massachusetts);  Allison B. Goldfine (Wayland, Massachusetts)
ABSTRACT Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
FILED Friday, June 05, 2009
APPL NO 12/479390
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/5.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003613 Cance et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) William G. Cance (Orchard Park, New York);  Vita Golubovskaya (Orchard Park, New York);  Elena V. Kurenova (West Falls, New York)
ABSTRACT The C-terminal domain of focal adhesion kinase (FAK-CD) was isolated using a Baculoviral system. Using phage display techniques, a phage encoding a 12 amino-acid peptide (peptide 35) and AV3 that binds to FAK-CD were identified. The peptides were also conjugated to TAT-FITC to produce a fluorescently labeled chimeric molecule capable of penetrating cell membranes. Contacting various breast cancer cell lines with these molecule caused detachment, rounding, apoptosis and cell death. These effects were not observed in normal (non-cancerous) breast cells.
FILED Wednesday, November 17, 2004
APPL NO 10/579529
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/18.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003618 Marban et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The John Hopkins University (Baltimore, Maryland)
INVENTOR(S) Eduardo Marban (Beverly Hills, California);  Mitsushige Murata (Tokyo, Japan)
ABSTRACT Disclosed is an invention for focally modulating the activity of a calcium channel in a mammal. In one aspect, the invention features a method that includes contacting a pre-determined tissue or organ region with a nucleic acid sequence encoding a GEM protein or a variant thereof to express the GEM protein or variant within the region. Typical methods further include expressing the GEM protein or variant so as to modulate the activity of the calcium channel. The invention has a wide spectrum of useful applications including treating a medical condition associated with unsuitable calcium channel activity.
FILED Thursday, October 02, 2003
APPL NO 10/678723
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003622 Wolfe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) Darren Wolfe (Pittsburgh, Pennsylvania);  Joseph C. Glorioso (Pittsburgh, Pennsylvania);  Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Darren P. Wolfe (Pittsburgh, Pennsylvania);  Joseph C. Glorioso (Pittsburgh, Pennsylvania);  David J. Fink (Ann Arbor, Michigan)
ABSTRACT The invention provides an expression cassette comprising a DNA sequence encoding amino acids 1-99 of human preproenkephalin, a DNA sequence encoding a precursor of a carboxy-amidated peptide flanked by dibasic cleavage sites and optionally a DNA sequence encoding a marker protein (such as Enhanced Green Fluorescent Protein (GFP)) all in operable linkage and under control of a promoter. Where the encoded precursor of a carboxy-amidated peptide is an agonist for an opioid receptor, the invention further provides a method of treating neuropathic pain by administering the gene transfer vector comprising such an expression cassette to a patient. The invention also provides a method for detecting a peptide having a desired effect comprising introducing a library of DNA sequences encoding one or more precursors of carboxy-amidated peptides into host cells; expressing the carboxy-amidated peptides encoded in the library to provide expression products; and screening from the polypeptide expression products for the desired effect.
FILED Wednesday, September 29, 2010
APPL NO 12/893255
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003628 Greene et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Mark I Greene (Penn Valley, Pennsylvania);  Ramachandran Murali (Swarthmore, Pennsylvania);  Masahiko Kinosaki (Tochigi, Japan)
ABSTRACT Methods of inhibiting osteoclastogenesis and the activity of osteoclasts are disclosed. Methods of treating patients who have diseases characterized bone loss are disclosed. According to the methods, an amount of a TRANCE/RANK inhibitor effective to inhibit osteoclastogenesis is administered to the patient. Pharmaceutical compositions which comprise TRANCE/RANK inhibitor in an amount effective to inhibit osteoclastogenesis. Methods of modulating dendritic cell maturation, T cell proliferation, and/or CD40 receptor systems in an individual are disclosed. The methods comprise the step of administering to the individual an amount of a TRANCE/RANK inhibitor effective to modulating dendritic cell maturation, T cell proliferation, and/or CD40 receptor systems.
FILED Monday, June 22, 2009
APPL NO 12/488868
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/175
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003629 Kim et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Hyun K. Kim (Bellingham, Washington);  Richard P. Blye (Highland, Maryland);  Pemmaraju N. Rao (San Antonio, Texas);  James W. Cessac (Floresville, Texas);  Carmie K. Acosta (San Antonio, Texas)
ABSTRACT A compound having the general formula:
in which: R1 is a member selected from the group consisting of —OCH3, —SCH3, —N(CH3)2, —NHCH3, —CHO, —COCH3 and —CHOHCH3; R2 is a member selected from the group consisting of halogen, alkyl, acyl, hydroxy, alkoxy, acyloxy, alkyl carbonate, cypionyloxy, S-alkyl and S-acyl; R3 is a member selected from the group consisting of alkyl, hydroxy, alkoxy and acyloxy; R4 is a member selected from the group consisting of hydrogen and alkyl; and X is a member selected from the group consisting of ═O and ═N—OR5, wherein R5 is a member selected from the group consisting of hydrogen and alkyl. In addition to providing the compounds of Formula I, the present invention provides methods wherein the compounds of Formula I are advantageously used, inter alia, to antagonize endogenous progesterone; to induce menses; to treat endometriosis; to treat dysmenorrhea; to treat endocrine hormone-dependent tumors; to treat uterine fibroids; to inhibit uterine endometrial proliferation; to induce labor; and for contraception.
FILED Thursday, December 17, 2009
APPL NO 12/641172
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/182
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003633 Robertson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Gavin P. Robertson (Hummelstown, Pennsylvania);  SubbRao V. Madhunapantula (Hershey, Pennsylvania);  Shantu Amin (Union City, New Jersey);  Dhimant Desai (Mechanicsburg, Pennsylvania)
ABSTRACT Anti-cancer compositions and methods are described including one or more compounds having the structural formula I: where R is phenyl, where R1 is (CH2)n—Se—C(═NH)—NH2, where R2 is (CH2)n—Se—C(═NH)—NH2 or R2 is H, and where each n is independently 2, 3, 4, 5, 6, 7, or 8. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including one or more compounds having the structural formula I to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including one or more compounds having the structural formula I to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. Compositions of the present invention inhibit Akt enzymes, iNOS, and increase MAP kinase activity such that cancer cells contacted with the compositions are inhibited.
FILED Tuesday, April 14, 2009
APPL NO 12/423366
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/183
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003674 Barklis
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) Eric Barklis (Lake Oswego, Oregon)
ABSTRACT Disclosed herein are compounds, compositions and methods for treating or ameliorating flavivirus infections. This is particularly important because the present disclosure provides methods for treating flavivirus infections for which there is no effective vaccine.
FILED Thursday, March 15, 2007
APPL NO 12/279831
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/360
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003687 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Kosan Biosciences Incorporated (Princeton, New Jersey)
INVENTOR(S) Steven D. Dong (San Francisco, California);  Daniel V. Santi (San Francisco, California)
ABSTRACT Esters of compounds in the leptomycin family, having a structure according to formula I
where R, R10, R11, R12, R13, and R14 are as defined herein, exhibit anti-tumor properties.
FILED Monday, September 11, 2006
APPL NO 11/991879
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/451
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003692 Schein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas);  Mission Pharmacal Co. (San Antonio, Texas)
INVENTOR(S) Catherine H. Schein (Friendswood, Texas);  Johnny W. Peterson (Dickinson, Texas);  Scott R. Gilbertson (Galveston, Texas);  Deliang Chen (League City, Texas);  Maria Estrella-Jimenez (Lawrenceville, New Jersey);  Mary A. Walter (Fair Oaks Ranch, Texas);  Jian Gao (Helotes, Texas)
ABSTRACT Fluorene-based molecules and their derivatives are described in compositions for the treatment of intestinal fluid loss.
FILED Friday, June 13, 2008
APPL NO 12/139212
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/468
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003693 Piomelli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Universita Degli Studi di Urbino (Urbino, Italy);  Universita Degl Studi di Parma (Parma, Italy)
INVENTOR(S) Daniele Piomelli (Irvine, California);  Andrea Duranti (Urbino, Italy);  Andrea Tontini (Pesaro, Italy);  Marco Mor (Ghedi, Italy);  Giorgio Tarzia (Petriano, Italy)
ABSTRACT Fatty acid amide hydrolase inhibitors of the Formula:
are provided wherein X is NH, CH2, O, or S; Q is O or S; Z is O or N; R is an aromatic moiety selected from the group consisting of substituted or unsubstituted aryl; substituted or unsubstituted biphenylyl, substituted or unsubstituted naphthyl, and substituted or unsubstituted phenyl; substituted or unsubstituted terphenylyl; substituted or unsubstituted cycloalkyl, heteroaryl, or alkyl; and R1 and R2 are independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, and substituted or unsubstituted phenyl, substituted or unsubstituted biphenylyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl; with the proviso that if Z is O, one of R1 and R2 is absent, and that if Z is N, optionally R1 and R2 may optionally be taken together to form a substituted or unsubstituted N-heterocycle or substituted or unsubstituted heteroaryl with the N atom to which they are each attached. Pharmaceutical compositions comprising the compounds of Formula I and methods of using them to inhibit FAAH and/or treat appetite disorders, glaucoma, pain, insomnia, and neurological and psychological disorders including anxiety disorders, epilepsy, and depression are provided.
FILED Friday, July 28, 2006
APPL NO 11/496051
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/481
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003764 Schmidt et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Laura S. Schmidt (Mt. Airy, Maryland);  Michelle Warren (New Market, Maryland);  Jorge R. Toro (Washington, District of Columbia);  Berton Zbar (Garrett Park, Maryland);  Michael L. Nickerson (Shepherdston, West Virginia);  W. Marston Linehan (North Bethesda, Maryland);  Maria L. Turner (Washington, District of Columbia)
ABSTRACT The present disclosure relates to Birt-Hogg-Dubé syndrome, nucleic acids encoding the BHD gene, and antibodies that specifically bind to the BHD protein (folliculin). In addition, the present disclosure relates to methods of diagnosing BHD disease and related conditions, such as spontaneous pneumothorax and kidney cancer, by detection of altered expression of folliculin using folliculin-specific antibodies.
FILED Friday, December 12, 2008
APPL NO 12/334361
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003801 Nicolaou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (LaJolla, California)
INVENTOR(S) Kyriacos C. Nicolaou (La Jolla, California);  Benjamin Pratt (San Diego, California);  Stellios Arseniyadis (Paris, France)
ABSTRACT A highly active synthetic epothilone compound whose activity exceeds that of either epothilone EpoA or EpoB when assayed as a cytotoxic agent against a cancer cell line is disclosed as is a pharmaceutical composition containing the synthetic epothilone.
FILED Thursday, November 09, 2006
APPL NO 12/092038
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
548/146
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003852 Gaxiola et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) University of Connecticut (Farmington, Connecticut);  Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Roberto A. Gaxiola (Tempe, Arizona);  Gerald R. Fink (Chestnut Hill, Massachusetts);  Seth L. Alper (Boston, Massachusetts)
ABSTRACT Transgenic plants are described which are engineered to overexpress vacuolar H+-PPase. Plants such as tobacco and petunia transformed with A. Thaliana AVP-1 are shown to have increased meristematic activity resulting in larger leaves, stem, flower, fruit, root structures, increased salt tolerance, enhanced drought and freeze tolerance. Methods of making such plants are also described.
FILED Tuesday, March 31, 2009
APPL NO 12/384115
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003948 Haselman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Michael Haselman (Renton, Washington);  Robert S. Miyaoka (Shoreline, Washington);  Thomas K. Lewellen (Port Ludlow, Washington);  Scott Hauck (Seattle, Washington)
ABSTRACT A method for estimating the start time of an electronic pulse generated in response to a detected event, for example the start time for pulses received in response to photon detection in positron emission tomography, includes providing a detector that detects an external event and generates an electronic analog pulse signal. A parameterized ideal curve shape is selected to represent analog pulse signals generated by the detector. Upon receiving an analog pulse signal, it may be filtered, and then digitized, and normalized based on the area of the digital signal. Using at least one point of the normalized digital pulse signal, a curve from the parameterized ideal curve shape is selected, that best represents the received analog pulse signal, and the selected curve is used to estimate the pulse start time.
FILED Monday, November 03, 2008
APPL NO 12/264093
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/362
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004281 Bottomley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Paul A. Bottomley (Columbia, Maryland);  Ananda Kumar (Baltimore, Maryland)
ABSTRACT Featured is a device for NMR or MRI signals from excited nuclei as well as related apparatus, systems and methods. The device includes a strip array antenna including one or more conductor and N reactive tuning components, where N is an integer ≧1 at least one of the N reactive components is electrically coupled to each of the one or more conductors as well as to ground/virtual ground. The apparent electrical length of the conductors is tuned with the reactive tuning components so it is equal to be about nλ/4, where n is an integer ≧1 and λ is the wavelength of the signal to be detected. The length of the strip also is such as to be substantially in the approximate range of 1.3 times the depth of interest. The strip conductors are also combined with loop coils to form quadrature detectors.
FILED Friday, September 10, 2010
APPL NO 12/879430
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/318
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005184 Chen
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Guang-Hong Chen (Madison, Wisconsin)
ABSTRACT A line scan cone beam CT imaging system irradiates an object with an x-ray cone beam for multiple views. A projection data set of the object is acquired at each view. Between views, the cone beam and detector array are translated along parallel lines in opposite directions. An image is generated by converting the cone beam projection data set of the real object into a parallel-beam projection data set corresponding to a virtual object and using a total variation minimization image reconstruction algorithm to reconstruct a virtual image of the virtual object. The reconstruction algorithm includes the constraint that the Fourier transform of the reconstructed virtual image matches the known Fourier coefficients in the set of converted parallel-beam projections of the virtual object. The reconstructed virtual image is then transformed into an image of the real object.
FILED Tuesday, April 24, 2007
APPL NO 11/739458
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005314 Ortyn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Aeronautics and Space Administration (NASA)
Ames Research Center (ARC)
APPLICANT(S)
ASSIGNEE(S) Amnis Corporation (Seattle, Washington)
INVENTOR(S) William Ortyn (Bainbridge Island, Washington);  David Basiji (Seattle, Washington);  Keith Frost (Seattle, Washington);  Luchuan Liang (Woodinville, Washington);  Richard Bauer (Kirkland, Washington);  Brian Hall (Seattle, Washington);  David Perry (Woodinville, Washington)
ABSTRACT A high speed, high-resolution flow imaging system is modified to achieve extended depth of field imaging. An optical distortion element is introduced into the flow imaging system. Light from an object, such as a cell, is distorted by the distortion element, such that a point spread function (PSF) of the imaging system is invariant across an extended depth of field. The distorted light is spectrally dispersed, and the dispersed light is used to simultaneously generate a plurality of images. The images are detected, and image processing is used to enhance the detected images by compensating for the distortion, to achieve extended depth of field images of the object. The post image processing preferably involves de-convolution, and requires knowledge of the PSF of the imaging system, as modified by the optical distortion element.
FILED Monday, December 11, 2006
APPL NO 11/609269
ART UNIT 2447 — Computer Networks
CURRENT CPC
Image analysis
382/275
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005526 Martin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) David C. Martin (Ann Arbor, Michigan);  Sarah Richardson-Burns (Ypsilanti, Michigan);  Donghwan Kim (Ann Arbor, Michigan);  Jeffrey L. Hendricks (Ann Arbor, Michigan);  Laura Povlich (Taylor, Michigan);  Mohamad Reza Abidian (Ann Arbor, Michigan);  Matthew Meier (Ann Arbor, Michigan)
ABSTRACT Bioelectrodes having enhanced biocompatible and biomimetic features are provided. Methods of making and using the bioelectrodes are further provided. A biologically integrated bioelectrode device and method for detecting electronic signals using a bioelectrode comprising a first electrically conductive substrate and a biological component. The bioelectrode also comprises a conductive polymer electrically coupling the first electrically conductive substrate and the biological component to define a bioelectrode. The bioelectrode can transmit or receive an electrical signal between the electrically conductive substrate and the biological component and conductive polymer.
FILED Wednesday, August 30, 2006
APPL NO 11/512479
ART UNIT 3739 — Optics
CURRENT CPC
Surgery
6/372
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005527 Zelenchuk
FUNDED BY
Department of Health and Human Services (HHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Luma Imaging Corporation (San Diego, California)
INVENTOR(S) Alex R. Zelenchuk (Stoughton, Massachusetts)
ABSTRACT A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, one of which corresponds to an isosbestic point. In one example, the isosbestic point occurs at about 431 nm. The intensities of the observed signals are normalized using the 431 nm intensity. A score is determined using the ratios in a discriminant analysis. The tissue under examination is resected or not, based on the diagnosis of disease or health, according to the outcome of the discriminant analysis.
FILED Wednesday, December 12, 2007
APPL NO 11/955165
ART UNIT 3737 — Optics
CURRENT CPC
Surgery
6/407
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005627 Porwancher
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Richard Porwancher (Princeton, New Jersey)
ABSTRACT A multivariate diagnostic method based on optimizing diagnostic likelihood ratios through the effective use of multiple diagnostic tests is disclosed. The Neyman-Pearson Lemma provides a mathematical basis to produce optimal diagnostic results. The method can comprise identifying those tests optimal for inclusion in a diagnostic panel, weighting the result of each component test based on a multivariate algorithm described below, adjusting the algorithm's performance to satisfy predetermined specificity criteria, generating a likelihood ratio for a given patient's test results through said algorithm, providing a clinical algorithm that estimates the pretest probability of disease based on individual clinical signs and symptoms, combining the likelihood ratio and pretest probability of disease through Bayes' Theorem to generate a posttest probability of disease, interpreting that result as either positive or negative for disease based on a cutoff value, and treating a patient for disease if the posttest probability exceeds the cutoff value.
FILED Saturday, September 08, 2007
APPL NO 11/852283
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/20
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 08001901 Bass
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jamie Bass (Elnora, Indiana)
ABSTRACT A system and method of detecting, processing, and selectively responding to radio frequency transmissions detected by at least one projectile deployed above a geographic area.
FILED Tuesday, January 11, 2011
APPL NO 13/004356
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/382
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08001902 Bass
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jamie Bass (Elnora, Indiana)
ABSTRACT A system and method of detecting, processing, and selectively responding to radio frequency transmissions detected by at least one projectile deployed above a geographic area.
FILED Thursday, October 09, 2008
APPL NO 12/248383
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/387
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002142 Losinski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Armand Losinski (Albuquerque, New Mexico);  Matthew Tehan (Albuquerque, New Mexico)
ABSTRACT An apparatus is provided for a fuel tank system for an air vehicle. The system comprises a container having an interior adapted to hold fuel, the container comprising a first opening placing the interior in fluid communication with the ambient atmosphere, and a volumetrically-adjustable sizing device adapted to change volume in response to changes in surrounding air pressure, the sizing element disposed within the container and adapted to contain a fluid.
FILED Thursday, June 19, 2008
APPL NO 12/142586
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Receptacles
220/721
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US 08002205 Lambert et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Delphi Technologies Holding S.arl (, None)
INVENTOR(S) Malcolm Lambert (Gillingham, United Kingdom);  Andrew Limmer (Sudbury, United Kingdom);  Mark Norman (Sudbury, United Kingdom);  Michael Mcloone (Sudbury, United Kingdom)
ABSTRACT An injection nozzle for an internal combustion engine has a valve member (10) with a seating line (112) defining a seat diameter, the seating line (112) being engageable with a seating surface (14) to control fuel injection by the nozzle, in use. The seating line is defined by an annular ridge (40, 44, 46), integrally formed with the valve needle (10), so as to reduce variations in the seat diameter which would otherwise arise at manufacture due to contact between the valve needle (10) and the seating surface (14) in regions other than at the seating line. The invention provides an advantage in manufacture as repeatability and consistency of the geometry, and in particular the effective seat diameter, of nozzle products is improved.
FILED Wednesday, October 06, 2004
APPL NO 10/575052
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Fluid sprinkling, spraying, and diffusing
239/533.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002235 Vyawahare et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Saurabh Vyawahare (Pasadena, California);  Suresh Situala (Pasadena, California);  Dvin Adalian (Alexandria, Virginia);  Axel Scherer (Laguna Beach, California)
ABSTRACT Microfluidic valves constructed from elastomeric materials as the valve body components and employing shape memory alloy in wire form as the valve actuator. Various configurations of individual valves having both normally open and normally closed states are described. Apparatus using such valves and providing logic functionality with fluidic logic outputs are discussed. Apparatus that can be used for materials processing at the nano- or micro-scale are presented. Various forms of logical control of valve arrays are explained.
FILED Tuesday, September 11, 2007
APPL NO 11/853531
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Valves and valve actuation
251/11
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US 08002599 Grabe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Zachary A. Grabe (West Palm Beach, Florida);  Jason B. Crawford (Wellington, Florida)
ABSTRACT Systems and methods for underwater descent rate reduction are provided. In one embodiment, a method for underwater descent rate reduction for an underwater delivery vehicle is provided. The method comprises: opening a first valve based on a first hydrostatic pressure to permit water to flow into a first chamber of a hydrostatic pressure driven piston assembly; developing a pressure differential across a piston head separating the first chamber from a second chamber of the hydrostatic pressure driven piston assembly; pushing the piston head into the second chamber to extend a piston rod from the hydrostatic pressure driven piston assembly; and pivoting a deflecting flap downward into a direction of vehicle descent as the piston rod extends.
FILED Wednesday, August 19, 2009
APPL NO 12/544015
ART UNIT 3617 — Fluid Handling and Dispensing
CURRENT CPC
Buoys, rafts, and aquatic devices
441/10
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US 08002914 D'Arche et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Steven P. D'Arche (Odon, Indiana);  Travis Swanson (Bloomfield, Indiana)
ABSTRACT A flash powder formulation for use in flash grenades that produces reduced smoke containing from about 10 percent by weight to about 60 percent by weight of zirconium hydride, from about 40 percent by weight to about 90 percent by weight CAN, and from zero percent by weight to about 5 percent by weight of a binder material.
FILED Tuesday, March 24, 2009
APPL NO 12/409956
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosive and thermic compositions or charges
149/37
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002917 Boddu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Veera M. Boddu (Champaign, Illinois);  Reddy Damavarapu (Hackettstown, New Jersey);  Krishnaiah Abburi (Tirupati, India)
ABSTRACT A method of adjusting the yield of a manufactured compound comprising primarily two energetic materials to yield a product comprising primarily one of the two energetic materials. Specifically, embodiments of the present invention provide a method of purifying a compound primarily comprising RDX and HMX to achieve a desired purity of RDX with an acceptable yield percentage. By adding sufficient acetonitrile (ACN) to the manufactured compound to dissolve it and form a solution; adding a pre-specified volume of water to the resultant solution and stirring sufficiently to precipitate at least the RDX; separating and drying the precipitate, a pre-specified purity and yield percentage of RDX may be obtained by varying the volume of water added. The process uses relatively environmentally benign recyclable solvents at ambient temperature and pressure reducing both environmental impact and energy costs.
FILED Monday, February 09, 2009
APPL NO 12/367562
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosive and thermic compositions or charges
149/92
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002956 O'Connor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Timothy J O'Connor (Troy, New York);  Frederick J Nelson (Schenectady, New York)
ABSTRACT A stand-off for maintaining the separation between an electrode and an object during a flow-through electroplating process is disclosed. The stand-off comprises a substantially streamlined shape that mitigates the effects of shadowing during deposition.
FILED Thursday, February 28, 2008
APPL NO 12/038941
ART UNIT 1759 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemistry: Electrical and wave energy
24/279
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US 08002958 Zhou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  Xintek, Inc. (Research Triangle Park, North Carolina)
INVENTOR(S) Otto Z. Zhou (Chapel Hill, North Carolina);  Bo Gao (Carrboro, North Carolina);  Guozhen Yue (Carrboro, North Carolina);  Soojin Oh (Carrboro, North Carolina)
ABSTRACT A method for depositing a coating of a nanostructure material onto a substrate includes: (1) forming a solution or suspension of containing the nanostructure material; (2) selectively adding “chargers” to the solution; (3) immersing electrodes in the solution, the substrate upon which the nanostructure material is to be deposited acting as one of the electrodes; (4) applying a direct and/or alternating current electrical field between the two electrodes for a certain period of time thereby causing the nanostructure materials in the solution to migrate toward and attach themselves to the substrate electrode; and (5) subsequent optional processing of the coated substrate.
FILED Friday, November 04, 2005
APPL NO 11/266318
ART UNIT 1759 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemistry: Electrical and wave energy
24/486
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US 08002963 Andelman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Biosource, Incorporated (London, United Kingdom)
INVENTOR(S) Marc D. Andelman (Worcester, Massachusetts);  Gregory S. Walker (Grafton, Massachusetts)
ABSTRACT Flow-through capacitors are provided with one or more charge barrier layers. Ions trapped in the pore volume of flow-through capacitors cause inefficiencies as these ions are expelled during the charge cycle into the purification path. A charge barrier layer holds these pore volume ions to one side of a desired flow stream, thereby increasing the efficiency with which the flow-through capacitor purifies or concentrates ions.
FILED Friday, August 01, 2008
APPL NO 12/221375
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/687
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003078 Lanza et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Barnes-Jewish Hospital (St. Louis, Missouri)
INVENTOR(S) Gregory M. Lanza (St. Louis, Missouri);  Samuel A. Wickline (St. Louis, Missouri);  Garry E. Kiefer (Richardson, Texas);  Phillip S. Athey (Lake Jackson, Texas)
ABSTRACT MRI contrast agents that employ paramagnetic agents and chemical exchange saturation transfer (paraCEST) and which are coupled to targeted particulate delivery vehicles provide sufficient concentration of the paraCEST contrast agents to obtain useful images of target tissues or organs. In addition, the image contrast may be switched on or off with a presaturation radio frequency pulse, avoiding the necessity obtaining pre-injection and post-injection images.
FILED Thursday, March 29, 2007
APPL NO 11/693647
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.365
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003374 Heeger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alan J. Heeger (Santa Barbara, California);  Chunhai Fan (Shanghai, China PRC);  Kevin Plaxco (Santa Barbara, California)
ABSTRACT A reagentless, reusable bioelectronic DNA, or other oligonucleotide sequence sensor is disclosed. The sensor includes an oligonucleotide (aptamer) probe tagged with a electroactive, redoxable moiety, self-assembled on or near an electrode. This surface-confined oligonucleotide (aptamer) probe structure undergoes hybridization-induced conformational change in the presence of the target which changes the electron-transfer distance between the redoxable moiety and the electrode thereby providing a detectable signal change. In an alternative embodiment, the target can harbor the redoxable moiety.
FILED Friday, July 29, 2005
APPL NO 11/193318
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/287.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003378 Wikswo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) John P. Wikswo (Brentwood, Tennessee);  Franz J. Baudenbacher (Franklin, Tennessee);  Ales Prokop (Nashville, Tennessee);  Eugene LeBoeuf (Franklin, Tennessee);  Chang Y. Chung (Franklin, Tennessee);  David E. Cliffel (Nashville, Tennessee);  Frederick R. Haselton (Nashville, Tennessee);  William H. Hofmeister (Nashville, Tennessee);  Charles P. Lin (Brentwood, Tennessee);  Lisa J. McCawley (Nashville, Tennessee);  Randall S. Reiserer (Nashville, Tennessee);  Mark A. Stremler (Franklin, Tennessee)
ABSTRACT A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel.
FILED Thursday, March 05, 2009
APPL NO 12/398825
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/289.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003385 Sukumar et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
Department of the Interior (DOI)
APPLICANT(S)
ASSIGNEE(S) Sanofi Pasteur Vax Design Corp. (Orlando, Florida)
INVENTOR(S) Selva Sukumar (Berkeley, California);  Mohey Eldin M. El Shikh (Richmond, Virginia);  John G. Tew (Mechanicsville, Virginia);  Guzman Sanchez-Schmitz (Orlando, Florida);  Donald Drake, III (Orlando, Florida);  Luis Mosquera (Oviedo, Florida);  Conan Li (Los Altos, California);  Anatoly M. Kachurin (Orlando, Florida);  Russell Higbee (Orlando, Florida);  Heather Fahlenkamp (Cleveland, Oklahoma);  Eric Mishkin (Winter Springs, Florida);  William L. Warren (Orlando, Florida)
ABSTRACT The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
FILED Wednesday, February 17, 2010
APPL NO 12/707563
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003387 Sukumar et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
Department of the Interior (DOI)
APPLICANT(S)
ASSIGNEE(S) Sanofi Pasteur Vaxdesign Corp. (Orlando, Florida)
INVENTOR(S) Selva Sukumar (Berkeley, California);  Mohey Eldin M. El Shikh (Richmond, Virginia);  John G. Tew (Mechanicsville, Virginia);  Guzman Sanchez-Schmitz (Orlando, Florida);  Donald Drake, III (Orlando, Florida);  Luis Mosquera (Oviedo, Florida);  Eric Mishkin (Winter Springs, Florida);  Anatoly M. Kachurin (Orlando, Florida);  Russell Higbee (Orlando, Florida);  Conan Li (Los Altos, California);  William L. Warren (Orlando, Florida);  Heather Fahlenkamp (Cleveland, Oklahoma)
ABSTRACT The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
FILED Thursday, December 21, 2006
APPL NO 11/642938
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/373
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003403 Levitsky
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Emitech, Inc (Fall River, Massachusetts)
INVENTOR(S) Igor A. Levitsky (Fall River, Massachusetts)
ABSTRACT A chemical sensor for detecting organic or inorganic target vapors and comprising a silicon member having a silicon surface with semiconductor pores therein, at least one luminescent sensory material entrapped in the semiconductor pores. The luminescent spectral material is exposed to the target vapors, wherein an excitation of the at least one luminescent sensory material results in a luminescent spectral response due to emission interference. The change in the luminescent spectral response is measured during this exposure.
FILED Wednesday, March 19, 2008
APPL NO 12/051233
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003504 Immorlica et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire);  Biogen IDEC MA Inc. (Cambridge, Massachusetts)
INVENTOR(S) Anthony A. Immorlica (Mont Vernon, New Hampshire);  Pane-chane Chao (Nashua, New Hampshire);  Kanin Chu (Nashua, New Hampshire)
ABSTRACT A method for fabrication of a field effect transistor gate, with or without field plates, includes the steps of defining a relatively thin Schottky metal layer by a lithography/metal liftoff or metal deposition/etch process on a semiconductor surface. This is followed by depositing a dielectric passivation layer over the entire wafer and defining a second lithographic pattern coincident with or slightly inset from the boundaries of the previously defined metal gate layer. This is followed by etching the dielectric using dry or wet etching techniques and stripping the resist, followed by exposing and developing a third resist pattern to define the thicker gate metal layers required for electrical conductivity and also for the field plate if one is utilized. The final step is depositing gate and/or field plate metal, resulting in a gate electrode and an integral field plate.
FILED Friday, August 31, 2007
APPL NO 12/086854
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/582
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003713 Carlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Steven Carlo (Bowie, Maryland);  Arthur W Snow (Alexandria, Virginia);  Richard S. Pong (Colesville, Maryland);  James S Shirk (Alexandria, Virginia);  Steven R Flom (Temple Hills, Maryland)
ABSTRACT High concentrations of dye may be prepared in combination with thermoplastic polymers and used in optical polymers as monomeric and dimeric molecular solutions. The method of preparing high concentration levels allows the control over the aggregation of dye molecules that is required to maintain effective nonlinear operation. The present invention is applicable to many systems and is essential to the successful production of working optical limiting devices and other optically transparent polymeric devices, as well as other photonic applications, such as nonlinear optics.
FILED Tuesday, December 08, 2009
APPL NO 12/633004
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
523/135
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003965 Grbic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Anthony Grbic (Ann Arbor, Michigan);  Roberto D. Merlin (Ann Arbor, Michigan)
ABSTRACT Planar sub-wavelength structures provide superlensing, i.e., electromagnetic focusing beyond the diffraction limit. The planar structures use diffraction to force the input field to converge to a spot on the focal plane. The sub-wavelength patterned structures manipulate the output wave in such a manner as to form a sub-wavelength focus in the near field. In some examples, the sub-wavelength structures may be linear grating-like structures that can focus electromagnetic radiation to lines of arbitrarily small sub-wavelength dimension, or two dimensional grating-like structures and Bessel (azimuthally symmetric) structures that can focus to spots of arbitrarily small sub-wavelength dimensions. The particular pattern for the sub-wavelength structures may be derived from the desired focus. Some examples describe sub-wavelength structures that have been implemented to focus microwave radiation to sub-wavelength dimensions in the near field.
FILED Monday, May 19, 2008
APPL NO 12/123434
ART UNIT 2821 — Optics
CURRENT CPC
Radiant energy
250/505.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003979 Cho et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Namchul Cho (Daejeon, South Korea);  Kaushik Roy Choudhury (Gainesville, Florida);  Yudhisthira Sahoo (Amherst, New York);  Kwang Sup Lee (Daejeon, South Korea);  Paras N. Prasad (Williamsville, New York)
ABSTRACT The present invention relates to a method of preparing a carbon nanotube-quantum dot conjugate having a high density of quantum dots (QDs) on its surface. This method involves providing a plurality of semiconductor quantum dots and providing a thiol-functionalized carbon nanotube having a plurality of terminal thiol groups on its surface. The plurality of semiconductor quantum dots are attached to the surface of the carbon nanotube under conditions effective to yield a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention also relates to a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention further relates to a photodetector device. This device includes a substrate and a nanocomposite layer. The nanocomposite layer includes a plurality of the carbon nanotube-quantum dot conjugates previously described.
FILED Monday, February 12, 2007
APPL NO 11/673850
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004017 Eden et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) J. Gary Eden (Mahomet, Illinois);  Sung-Jin Park (Champaign, Illinois);  Kwang-Soo Kim (Champaign, Illinois)
ABSTRACT A preferred embodiment microcavity plasma device array of the invention includes a plurality of first metal circumferential metal electrodes that surround microcavities in the device. The first circumferential electrodes are buried in a metal oxide layer and surround the microcavities in a plane transverse to the microcavity axis, while being protected from plasma in the microcavities by the metal oxide. In embodiments of the invention, the circumferential electrodes can be connected in patterns. A second electrode(s) is arranged so as to be isolated from said first electrodes by said first metal oxide layer. In some embodiments, the second electrode(s) is in a second layer, and in other embodiments the second electrode(s) is also within the first metal oxide layer. A containing layer, e.g., a thin layer of glass, quartz, or plastic, seals the discharge medium (plasma) into the microcavities. In a preferred method of formation embodiment, a metal foil or film is obtained or formed with micro-holes. The foil is anodized to form metal oxide. One or more self-patterned metal electrodes are automatically formed and buried in the metal oxide created by the anodization process. The electrodes form in a closed circumference around each microcavity in a plane(s) transverse to the microcavity axis, and can be electrically isolated or connected. Preferred embodiments provide inexpensive microplasma device electrode structures and a fabrication method for realizing microplasma arrays that are lightweight and scalable to large areas. Electrodes buried in metal oxide and complex patterns of electrodes can also be formed without reference to microplasma devices—that is, for general electrical circuitry.
FILED Tuesday, July 24, 2007
APPL NO 11/880698
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/211
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004127 Potter
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Foster-Miller, Inc. (Waltham, Massachusetts)
INVENTOR(S) Steven D. Potter (Bedford, Massachusetts)
ABSTRACT A rotary reluctance motor includes a set of inner disks each having an inner diameter root, an outer diameter free end, and a plurality of alternating high permeability teeth and low permeability material segments. A set of outer disks is interleaved with the inner disks to form a disk stack. Each outer disk has an outer diameter root, an inner diameter free end, and a plurality of alternating high permeability teeth and low permeability material segments. The inner and outer disks are configured to bear against and support each other in response to axial magnetic forces. Flux return portions are disposed axially adjacent the disks at each end of the disk stack. A coil is associated with the roots of one of the sets of disks and configured to provide axial flux through the disk stack to rotate one set of disks with respect to the other set of disks.
FILED Thursday, April 24, 2008
APPL NO 12/150003
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/49.440
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004156 Symko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Orest G. Symko (Salt Lake City, Utah);  Young S. Kwon (Salt Lake City, Utah)
ABSTRACT A thermoacoustic array energy converter consists of heat driven thermoacoustic prime movers in parallel coupled by means of an acoustic cavity to a piezoelectric electrical generator whose output is rectified and fed to an energy storage element. The prime movers convert heat to sound in a resonator. The sound form a phase-locked array is converted to electricity by means of the piezoelectric element. The generated electric energy is converted to DC by means of a rectifier set and it is then stored in a battery or supercapacitor. The generated electric energy can also be converted to power line frequency.
FILED Wednesday, January 23, 2008
APPL NO 12/018762
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/339
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004216 Kayser
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David J. Kayser (Saint Inigoes, Maryland)
ABSTRACT A variable intensity LED illumination system is configured to provide a change in luminance versus input voltage that corresponds to a desired transfer function, such as the dimming characteristics of an incandescent lamp, which more closely resembles the response of the human eye. The system also advantageously provides overvoltage protection, increased brightness, energy efficiency, and significantly better longevity and ruggedness, compared to incandescent lamps.
FILED Friday, May 02, 2008
APPL NO 12/114063
ART UNIT 2821 — Electrical Circuits and Systems
CURRENT CPC
Electric lamp and discharge devices: Systems
315/312
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US 08004278 Worledge et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York);  Infineon Technologies North America Corp. (San Jose, California)
INVENTOR(S) Daniel Christopher Worledge (Poughquag, New York);  Philip Louis Trouilloud (Norwood, New Jersey);  David William Abraham (Croton-on-Hudson, New York);  Joerg Dietrich Schmid (Hopewell Junction, New York)
ABSTRACT Probes are electrically connected to a surface of a tunnel junction film stack comprising a free layer, a tunnel barrier, and a pinned layer. Resistances are determined for a variety of probe spacings and for a number of magnetizations of one of the layers of the stack. The probe spacings are a distance from a length scale, which is related to the Resistance-Area (RA) product of the tunnel junction film stack. Spacings from as small as possible to about 40 times the length scale are used. Beneficially, the smallest spacing between probes used during a resistance measurement is under 100 microns. A measured in-plane MagnetoResistance (MR) curve is determined from the “high” and “low” resistances that occur at the two magnetizations of this layer. The RA product, resistances per square of the free and pinned layers, and perpendicular MR are determined through curve fitting.
FILED Tuesday, August 11, 2009
APPL NO 12/539080
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/223
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004455 Wright et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Buford S. Wright (Bedford, Indiana);  Joseph Dang (Bloomington, Indiana)
ABSTRACT A method and apparatus for simulating antenna apparatuses are provided. In an illustrative embodiment, the apparatus comprises a first portion configured to produce a first and third plurality of signals and to receive a second plurality of signals from a transmitter, wherein said first and third plurality of signals are determined by more than one of a plurality of relationships between said transmitter and at least one antenna apparatus adapted to receive signals from said transmitter.
FILED Saturday, February 09, 2008
APPL NO 12/028798
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Directive radio wave systems and devices
342/169
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004660 Brown
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washingotn, District of Columbia)
INVENTOR(S) Jerry G. Brown (Bloomington, Indiana)
ABSTRACT A simulation system for predicting a likelihood of whether a target object positioned in an environment will be detected by a detection system when illuminated by a laser source. The simulation system may be used for a laser rangefinder application and a laser designator application. The simulation system may provide a detection probability of the target object at a specified range to the detection system or a plurality of detection probabilities as a function of the range to the detection system. The simulation system may provide an indication of an overlap of the beam provided by the laser source on the target object. The simulation system may determine the effect of vibration on the detection of the target object at a specified range.
FILED Tuesday, March 31, 2009
APPL NO 12/414773
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Optics: Measuring and testing
356/5.20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004676 Prasad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) Paras N. Prasad (Williamsville, New York);  Przemyslaw P. Markowicz (Woodbury, Minnesota);  Wing Cheung Law (Amherst, New York);  Andrei Kabashin (St.-Leonard, Canada);  Sergiy Patskovsky (Montreal, Canada)
ABSTRACT A method is provided for detection of analytes using the Surface Plasmon Resonance effect. The method comprises providing a metal film on a transparent substrate. The free surface of the metal film is exposed to a test sample. An anlyte in the sample can interact directly with the metal film or via analyte binding molecules (ABMs) complexed to the film. Light is directed incident to the surface of film in contact with the substrate. Light is reflected from the surface of the film under SPR conditions. The reflected light is collected and the second and/or third harmonics of the resulting electrical signal, which are indicative of the phase and polarization state of the reflected light, are determined. The second and third harmonics are correlated to the presence and/or concentration of the analyte.
FILED Monday, February 11, 2008
APPL NO 12/069700
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/369
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US 08004762 Cathey, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Regents Of The University Of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Wade Thomas Cathey, Jr. (Boulder, Colorado);  Edward Raymond Dowski, Jr. (Lafayette, Colorado)
ABSTRACT Systems and methods for generating an optical image include forming an optical image with at least one optical element of an optical imager while modifying wavefront phase. Modifying the phase does not reduce an optical bandpass limited by an aperture of the optical imager. The systems and methods also include detecting the optical image over a range of spatial frequencies such that there are no zeros in an optical transfer function of the optical imager over detected spatial frequencies within the optical bandpass and over an extended depth of focus that is larger than a depth of focus occurring without modifying wavefront phase.
FILED Monday, October 13, 2008
APPL NO 12/250343
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/558
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US 08004841 Cipolla et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Thomas M. Cipolla (Katonah, New York);  Shurong Tian (Mount Kisco, New York);  Evan George Colgan (Chestnut Ridge, New York);  Paul W. Coteus (Yorktown Heights, New York);  Shawn Anthony Hall (Pleasantville, New York)
ABSTRACT A cooling or heat transfer apparatus and method is disclosed for cooling an electronic device. The apparatus includes a heat producing electronic device which may include an electronic circuit card with many heat sources. A heat transfer device is connected to the heat producing electronic device which is thermally communicating with the heat producing device for transferring heat from the heat producing device to the heat transfer device. A heat conduit is connected to the heat transfer device and thermally communicating with the heat transfer device for transferring heat to the heat conduit from the heat transfer device. A cooling housing is connected to the heat conduit and the cooling housing thermally communicating with the heat conduit for transferring heat to the cooling housing from the heat conduit. The apparatus enables the replacement of circuit cards in the field because it eliminates the need to apply thermal-interface materials.
FILED Tuesday, May 06, 2008
APPL NO 12/115618
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/699
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005002 Gandham et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Shashidhar R. Gandham (Richardson, Texas);  Ying Zhang (Cupertino, California);  Qingfeng Huang (San Jose, California)
ABSTRACT One embodiment of the present invention provides a system that performs a query-based convergecast scheduling in a convergecast network, which includes a base-station and a plurality of nodes. During operation, the system receives a convergecast tree for the convergecast network. Each node in the convergecast tree is associated with a hop-count to the base-station through a specific branch and each node can generate zero or more packets to transmit. Next, the system initializes a query from the base-station, wherein the query is successively propagated to the nodes through the branches. In response to the query, the system computes distributed-timing-information indicating a packet transmission schedule for the nodes. The system next aggregates the distributed-timing-information associated with the nodes toward the base-station through the branches. The system then forwards the aggregated distributed-timing-information to the plurality of nodes. Finally, each node constructs an optimized-convergecast-schedule for the convergecast tree based on the aggregated distributed-timing-information.
FILED Friday, November 02, 2007
APPL NO 11/934676
ART UNIT 2477 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/252
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005124 Then et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Han Wui Then (Urbana, Illinois);  Gabriel Walter (Champaign, Illinois);  Milton Feng (Champaign, Illinois);  Nick Holonyak, Jr. (Urbana, Illinois)
ABSTRACT A method for producing wide bandwidth laser emission responsive to high frequency electrical input signals, including the following steps: providing a heterojunction bipolar transistor device having collector, base, and emitter regions; providing at least one quantum size region in the base region, and enclosing at least a portion of the base region in an optical resonant cavity; coupling electrical signals, including the high frequency electrical input signals, with respect to the collector, base and emitter region, to cause laser emission from the transistor device; and reducing the operating beta of the transistor laser device to enhance the optical bandwidth of the laser emission in response to the high frequency electrical signals.
FILED Wednesday, October 14, 2009
APPL NO 12/587895
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/46.11
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005176 Song
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William S. Song (Lexington, Massachusetts)
ABSTRACT Described are nonlinear filter processors having an array of polynomial nonlinear filters including a first polynomial nonlinear filter and a last polynomial nonlinear filter. The first polynomial nonlinear filter has an input terminal for receiving an input data sample. The polynomial nonlinear filters systolically pass the input data sample from the first polynomial nonlinear filter to the last polynomial nonlinear filter. Each polynomial nonlinear filter produces an output data sample based on the input data sample. In addition, each polynomial nonlinear filter other than the last polynomial nonlinear filter systolically passes the output data sample generated by that polynomial nonlinear filter to a neighboring polynomial nonlinear filter. Each polynomial nonlinear filter other than the first polynomial nonlinear filter sums a nonlinearly filtered input data sample produced by that polynomial nonlinear filter with the output data sample received from a neighboring polynomial nonlinear filter.
FILED Thursday, February 14, 2008
APPL NO 12/030913
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005257 Venetsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Larry Venetsky (Mount Laurel, New Jersey);  Jeffrey W. Tieman (Leonardtown, Maryland)
ABSTRACT A method of identifying a human gesture using a machine includes providing a time sequence of data related to the human gesture; transforming the time sequence of data into waveforms; extracting features from the waveforms; and identifying the human gesture based on the extracted features.
FILED Wednesday, July 23, 2008
APPL NO 12/177913
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005332 Schmidt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Brigham Young University (Provo, Utah)
INVENTOR(S) Holger Schmidt (Capitola, California);  Aaron Roe Hawkins (Provo, Utah)
ABSTRACT An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate.
FILED Wednesday, April 02, 2008
APPL NO 12/061165
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/131
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005486 Pahlavan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Kaveh Pahlavan (Newton, Massachusetts);  Nayef Al-Sindi (Malden, Massachusetts);  Bardia Alavi (Shaker Heights, Ohio)
ABSTRACT Methods and systems for configuring ad-hoc networks, especially a self-configuring wireless sensor networks, are described. The network has an initial number of anchors with known positions that broadcast a signal. The signals are received by distributed nodes whose position is not yet known. The nodes rank the received signal based on a Quality of Link (QoL; received signal strength) and compute a Quality of position Estimate (QoE) for the node. The node with the best QoE is elevated to anchor. This process gradually increases the number of available anchors in the network and hence the position accuracy for additional nodes. The system can be used for geolocation of soldiers in the indoor combat, tracking the location of firefighter and other emergency personnel in rescue missions, etc.
FILED Tuesday, January 22, 2008
APPL NO 12/009836
ART UNIT 2617 — Optics
CURRENT CPC
Telecommunications
455/456.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005631 Barger et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S) James E. Barger (Winchester, Massachusetts);  Stephen D. Milligan (Stow, Massachusetts);  Marshall Seth Brinn (Newton, Massachusetts);  Richard J. Mullen (Needham, Massachusetts)
ABSTRACT Systems and methods for locating the shooter of supersonic projectiles are described. The system uses at least five, preferably seven, spaced acoustic sensors. Sensor signals are detected for shockwaves and muzzle blast, wherein muzzle blast detection can be either incomplete coming from less than 4 sensor channels, or inconclusive due to lack of signal strength. Shooter range can be determined by an iterative computation and/or a genetic algorithm by minimizing a cost function that includes timing information from both shockwave and muzzle signal channels. Disambiguation is significantly improved over shockwave-only measurements.
FILED Friday, March 07, 2008
APPL NO 12/074884
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/60
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005767 Cassella
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Vincent A. Cassella (W. Springfield, Virginia)
ABSTRACT The present invention enables identification of events such as target. From training target event data the present a very large number of clusters are formed for each class based on Euclidean distance using a repetitive k-means clustering process. Features from each cluster are identified by extracting out their dominant eigenvectors. Once all of the dominant eigenvectors have been identified, they define the relevant space of the cluster. New target event data is compared to each cluster by projecting it onto the relevant and noise spaces. The more the data lies within the relevant space and the less it lies within the noise space the more similar the data is to a cluster. The new target event data is then classified based on the training target event data.
FILED Friday, June 01, 2007
APPL NO 11/756690
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005839 Aggarwal et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charu C. Aggarwal (Mohegan Lake, New York);  Philip Shi-Lung Yu (Chicago, Illinois)
ABSTRACT Techniques are disclosed for aggregation in uncertain data in data processing systems. For example, a method of aggregation in an application that involves an uncertain data set includes the following steps. The uncertain data set along with uncertainty information is obtained. One or more clusters of data points are constructed from the data set. Aggregate statistics of the one or more clusters and uncertainty information are stored. The data set may be data from a data stream. It is realized that the use of even modest uncertainty information during an application such as a data mining process is sufficient to greatly improve the quality of the underlying results.
FILED Thursday, February 28, 2008
APPL NO 12/039076
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/737
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 08001672 Meinke
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Advanced Magnet Lab, Inc (Palm Bay, Florida)
INVENTOR(S) Rainer Meinke (Melbourne, Florida)
ABSTRACT A method for manufacture of a conductor assembly along a curvilinear axis. The assembly may be of the type which, when conducting current, generates a magnetic field or in which, in the presence of a changing magnetic field, a voltage is induced. In one example, the assembly includes a structure having a curved shape extending along the axis. A surface of the structure is positioned for formation of a channel along the curved shape. The structure is rotated about a second axis. While rotating the structure, a channel is formed in the surface that results in a helical shape in the structure. The channel extends both around and along the first axis.
FILED Thursday, June 05, 2008
APPL NO 12/133739
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/605
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002854 Muradov
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Nazim Z. Muradov (Melbourne, Florida)
ABSTRACT A novel process and apparatus are disclosed for sustainable CO2-free production of hydrogen and carbon by thermocatalytic decomposition (dissociation, pyrolysis, cracking) of hydrocarbon fuels over carbon-based catalysts in the absence of air and/or water. The apparatus and thermocatalytic process improve the activity and stability of carbon catalysts during the thermocatalytic process and produce both high purity hydrogen (at least, 99.0 volume %) and carbon, from any hydrocarbon fuel, including sulfurous fuels. In a preferred embodiment, production of hydrogen and carbon is achieved by both internal and external activation of carbon catalysts. Internal activation of carbon catalyst is accomplished by recycling of hydrogen-depleted gas containing unsaturated and aromatic hydrocarbons back to the reactor. External activation of the catalyst can be achieved via surface gasification with hot combustion gases during catalyst heating. The process and apparatus can be conveniently integrated with any type of fuel cell to generate electricity.
FILED Friday, December 29, 2006
APPL NO 11/648453
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Gas: Heating and illuminating
048/61
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002874 Huang et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Membrane Technology and Research, Inc. (Menlo Park, California)
INVENTOR(S) Yu Huang (Palo Alto, California);  Jennifer Ly (San Jose, California);  Tiem Aldajani (San Jose, California);  Richard W. Baker (Palo Alto, California)
ABSTRACT Processes for dehydrating an organic/water solution by pervaporation or vapor separation using fluorinated membranes. The processes are particularly useful for treating mixtures containing light organic components, such as ethanol, isopropanol or acetic acid.
FILED Tuesday, March 06, 2007
APPL NO 11/715245
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Gas separation: Processes
095/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003045 Muralidharan et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Govindarajan Muralidharan (Knoxville, Tennessee);  Vinod Kumar Sikka (Oak Ridge, Tennessee);  Philip J. Maziasz (Oak Ridge, Tennessee);  Roman I. Pankiw (Greensburg, Pennsylvania)
ABSTRACT A cast, austenitic steel composed essentially of, expressed in weight percent of the total composition, about 0.4 to about 0.7 C, about 20 to about 30 Cr, about 20 to about 30 Ni, about 0.5 to about 1 Mn, about 0.6 to about 2 Si, about 0.05 to about 1 Nb, about 0.05 to about 1 W, about 0.05 to about 1.0 Mo, balance Fe, the steel being essentially free of Ti and Co, the steel characterized by at least one microstructural component selected from the group consisting of MC, M23C6, and M(C, N).
FILED Friday, June 04, 2010
APPL NO 12/793930
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys or metallic compositions
420/53
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003070 Fox et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Robert V. Fox (Idaho Falls, Idaho);  Rene G. Rodriguez (Pocatello, Idaho);  Joshua Pak (Pocatello, Idaho)
ABSTRACT Single source precursors are subjected to carbon dioxide to form particles of material. The carbon dioxide may be in a supercritical state. Single source precursors also may be subjected to supercritical fluids other than supercritical carbon dioxide to form particles of material. The methods may be used to form nanoparticles. In some embodiments, the methods are used to form chalcopyrite materials. Devices such as, for example, semiconductor devices may be fabricated that include such particles. Methods of forming semiconductor devices include subjecting single source precursors to carbon dioxide to form particles of semiconductor material, and establishing electrical contact between the particles and an electrode.
FILED Thursday, March 13, 2008
APPL NO 12/047956
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/508
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003073 Pez et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Air Products and Chemicals, Inc. (Allentown, Pennsylvania)
INVENTOR(S) Guido Peter Pez (Allentown, Pennsylvania);  Alan Charles Cooper (Macungie, Pennsylvania);  Aaron Raymond Scott (Allentown, Pennsylvania)
ABSTRACT Processes are provided for the storage and release of hydrogen by means of dehydrogenation of hydrogen carrier compositions where at least part of the heat of dehydrogenation is provided by a hydrogen-reversible selective oxidation of the carrier. Autothermal generation of hydrogen is achieved wherein sufficient heat is provided to sustain the at least partial endothermic dehydrogenation of the carrier at reaction temperature. The at least partially dehydrogenated and at least partially selectively oxidized liquid carrier is regenerated in a catalytic hydrogenation process where apart from an incidental employment of process heat, gaseous hydrogen is the primary source of reversibly contained hydrogen and the necessary reaction energy.
FILED Tuesday, April 15, 2008
APPL NO 12/103205
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/651
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003220 Melechko et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Anatoli V. Melechko (Oak Ridge, Tennessee);  Timothy E. McKnight (Greenback, Tennessee);  Michael A. Guillorn (Ithaca, New York);  Bojan Ilic (Ithaca, New York);  Vladimir I. Merkulov (Knoxville, Tennessee);  Mitchel J. Doktycz (Knoxville, Tennessee);  Douglas H. Lowndes (Knoxville, Tennessee);  Michael L. Simpson (Knoxville, Tennessee)
ABSTRACT Methods, manufactures, machines and compositions are described for nanotransfer and nanoreplication using deterministically grown sacrificial nanotemplates. An apparatus, includes a substrate and a nanoreplicant structure coupled to a surface of the substrate.
FILED Tuesday, November 13, 2007
APPL NO 11/985395
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/446
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003404 Rotello et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Vincent Rotello (Belchertown, Massachusetts);  Uwe Bunz (Atlanta, Georgia);  Ronnie Phillips (Atlanta, Georgia);  Oscar Miranda (Amherst, Massachusetts);  Chang-Cheng You (Waltham, Massachusetts)
ABSTRACT Compositions, methods and related apparatus, as can be used for selective pathogen detection and identification.
FILED Monday, November 17, 2008
APPL NO 12/313137
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003497 Yang et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Peidong Yang (El Cerrito, California);  Heonjin Choi (Seoul, South Korea);  Sangkwon Lee (Daejeon, South Korea);  Rongrui He (Albany, California);  Yanfeng Zhang (El Cerrito, California);  Tevye Kuykendal (Berkeley, California);  Peter Pauzauskie (Berkeley, California)
ABSTRACT A method for is disclosed for fabricating diluted magnetic semiconductor (DMS) nanowires by providing a catalyst-coated substrate and subjecting at least a portion of the substrate to a semiconductor, and dopant via chloride-based vapor transport to synthesize the nanowires. Using this novel chloride-based chemical vapor transport process, single crystalline diluted magnetic semiconductor nanowires Ga1-xMnxN (x=0.07) were synthesized. The nanowires, which have diameters of ˜10 nm to 100 nm and lengths of up to tens of micrometers, show ferromagnetism with Curie temperature above room temperature, and magnetoresistance up to 250 Kelvin.
FILED Thursday, June 29, 2006
APPL NO 11/480280
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/478
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003571 Stan et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Liliana Stan (Los Alamos, New Mexico);  Quanxi Jia (Los Alamos, New Mexico);  Stephen R. Foltyn (Los Alamos, New Mexico)
ABSTRACT A composite structure is provided including a base substrate, an IBAD oriented material upon the base substrate, and a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material. Additionally, an article is provided including a base substrate, an IBAD oriented material upon the base substrate, a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material, and a thick film upon the cubic metal oxide material. Finally, a superconducting article is provided including a base substrate, an IBAD oriented material upon the base substrate, a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material, and an yttrium barium copper oxide material upon the cubic metal oxide material.
FILED Tuesday, August 07, 2007
APPL NO 11/890812
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Superconductor technology: Apparatus, material, process
55/237
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003730 Celina
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Mathias C. Celina (Albuquerque, New Mexico)
ABSTRACT An epoxy resin mixture with at least one epoxy resin of between approximately 60 wt % and 90 wt %, a maleic anhydride of between approximately 1 wt % and approximately 30 wt %, and an imidazole catalyst of less than approximately 2 wt % where the resin mixture is formed from at least one epoxy resin with a 1-30 wt % maleic anhydride compound and an imidazole catalyst at a temperature sufficient to keep the maleic anhydride compound molten, the resin mixture reacting to form a foaming resin which can then be cured at a temperature greater than 50° C. to form an epoxy foam.
FILED Tuesday, December 16, 2008
APPL NO 12/335925
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
525/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003855 Somerville et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) Carnegie Institution of Washington (Washington, District of Columbia);  Monsanto Company, Inc. (St. Louis, Missouri)
INVENTOR(S) Chris Somerville (Portola Valley, California);  Pierre Broun (Burlingame, California);  Frank van de Loo (Weston, Australia);  Sekhar S. Boddupalli (Manchester, Michigan)
ABSTRACT This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.
FILED Thursday, September 27, 2007
APPL NO 11/905067
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/306
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003937 Kertesz et al.
FUNDED BY
Department of Energy (DOE)
National Security Agency (NSA)
Center for Communications and Computing (CC) at Alexandria, VA
Federally Funded Research and Development Center (FFRDC)
Operated by Institute for Defense Analyses (IDA) at Alexandria, VA
APPLICANT(S)
ASSIGNEE(S) UT-Battelle (Oak Ridge, Tennessee)
INVENTOR(S) Vilmos Kertesz (Knoxville, Tennessee);  Gary Van Berkel (Clinton, Tennessee)
ABSTRACT An electrospray ion (ESI) source and method capable of ionizing an analyte molecule without oxidizing or reducing the analyte of interest. The ESI source can include an emitter having a liquid conduit, a working electrode having a liquid contacting surface, a spray tip, a secondary working electrode, and a charge storage coating covering partially or fully the liquid contacting surface of the working electrode. The liquid conduit, the working electrode and the secondary working electrode can be in liquid communication. The electrospray ion source can also include a counter electrode proximate to, but separated from, said spray tip. The electrospray ion source can also include a power system for applying a voltage difference between the working electrodes and a counter-electrode. The power system can deliver pulsed voltage changes to the working electrodes during operation of said electrospray ion source to minimize the surface potential of the charge storage coating.
FILED Thursday, September 25, 2008
APPL NO 12/237892
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/288
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003982 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Zhong L. Wang (Marietta, Georgia);  Sheng Xu (Atlanta, Georgia)
ABSTRACT An electric power generator includes a first conductive layer, a plurality of semiconducting piezoelectric nanostructures, a second conductive layer and a plurality of conductive nanostructures. The first conductive layer has a first surface from which the semiconducting piezoelectric nanostructures extend. The second conductive layer has a second surface and is parallel to the first conductive layer so that the second surface faces the first surface of the first conductive layer. The conductive nanostructures depend downwardly therefrom. The second conductive layer is spaced apart from the first conductive layer at a distance so that when a force is applied, the semiconducting piezoelectric nanostructures engage the conductive nanostructures so that the piezoelectric nanostructures bend, thereby generating a potential difference across the at semiconducting piezoelectric nanostructures and also thereby forming a Schottky barrier between the semiconducting piezoelectric nanostructures and the conductive nanostructures.
FILED Thursday, December 18, 2008
APPL NO 12/338131
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/43
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004140 Alexander et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) James Pellegrino Alexander (Ballston Lake, New York);  Ayman Mohamed Fawzi EL-Refaie (Niskayuna, New York);  Murtuza Lokhandwalla (Clifton Park, New York);  Manoj Ramprasad Shah (Latham, New York);  Jeremy Daniel VanDam (West Coxsackie, New York)
ABSTRACT An internal permanent magnet (IPM) machine is provided. The IPM machine includes a stator assembly and a stator core. The stator core also includes multiple stator teeth. The stator assembly is further configured with stator windings to generate a stator magnetic field when excited with alternating currents and extends along a longitudinal axis with an inner surface defining a cavity. The IPM machine also includes a rotor assembly and a rotor core. The rotor core is disposed inside the cavity and configured to rotate about the longitudinal axis. The rotor assembly further includes a shaft. The shaft further includes multiple protrusions alternately arranged relative to multiple bottom structures provided on the shaft. The rotor assembly also includes multiple stacks of laminations disposed on the protrusions and dovetailed circumferentially around the shaft. The rotor assembly further includes multiple pair of permanent magnets for generating a magnetic field, which magnetic field interacts with the stator magnetic field to produce a torque. The multiple pair of permanent magnets are disposed between the stacks. The rotor assembly also includes multiple middle wedges mounted between each pair of the multiple permanent magnets.
FILED Thursday, April 30, 2009
APPL NO 12/432894
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/156.560
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08003008 Huebner et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Clemson University (Clemson, South Carolina)
INVENTOR(S) Christopher F. Huebner (Clemson, South Carolina);  David D. Evanoff (Cullowhee, North Carolina);  Joseph B. Carroll (Bradford, Massachusetts);  Stephan H. Foulger (Clemson, South Carolina)
ABSTRACT Color-tailored and white-light emitting polymer colloid-based OLEDs are disclosed. Devices include electroluminescent (EL) colloidal conductive polymer systems that can include EL dyes or other EL materials. Systems can sequester multiple EL components in different colloids in a single emissive layer of an EL device with little or no appreciable energy transfer between colloids. Devices can exhibit tailored emissions over a broad range of wavelengths through mixing of, e.g., red, green and blue PLED colloids. Disclosed methods including incorporation of one or more electroluminescent dyes into a semiconductive EL polymer colloid that can isolate the dyes and prevent energy transfer while retaining individual color emission.
FILED Wednesday, October 08, 2008
APPL NO 12/247270
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compositions
252/301.160
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003374 Heeger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alan J. Heeger (Santa Barbara, California);  Chunhai Fan (Shanghai, China PRC);  Kevin Plaxco (Santa Barbara, California)
ABSTRACT A reagentless, reusable bioelectronic DNA, or other oligonucleotide sequence sensor is disclosed. The sensor includes an oligonucleotide (aptamer) probe tagged with a electroactive, redoxable moiety, self-assembled on or near an electrode. This surface-confined oligonucleotide (aptamer) probe structure undergoes hybridization-induced conformational change in the presence of the target which changes the electron-transfer distance between the redoxable moiety and the electrode thereby providing a detectable signal change. In an alternative embodiment, the target can harbor the redoxable moiety.
FILED Friday, July 29, 2005
APPL NO 11/193318
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/287.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003397 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Qian Wang (Columbia, South Carolina);  Siqi Li (Columbia, South Carolina)
ABSTRACT A polymeric sensing fluid for detecting the presence of glucose and systems and methods of its use are generally disclosed. The polymeric sensing fluid includes a polymer in a solvent (e.g., an aqueous solvent). The polymer has a plurality of boronic acid moieties extending from its polymeric backbone. As such, the polymeric sensing fluid is configured to increase in viscosity upon addition of glucose due to crosslinking between the boronic acid moieties of the polymer and glucose.
FILED Thursday, January 29, 2009
APPL NO 12/361825
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/95
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003404 Rotello et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Vincent Rotello (Belchertown, Massachusetts);  Uwe Bunz (Atlanta, Georgia);  Ronnie Phillips (Atlanta, Georgia);  Oscar Miranda (Amherst, Massachusetts);  Chang-Cheng You (Waltham, Massachusetts)
ABSTRACT Compositions, methods and related apparatus, as can be used for selective pathogen detection and identification.
FILED Monday, November 17, 2008
APPL NO 12/313137
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003497 Yang et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Peidong Yang (El Cerrito, California);  Heonjin Choi (Seoul, South Korea);  Sangkwon Lee (Daejeon, South Korea);  Rongrui He (Albany, California);  Yanfeng Zhang (El Cerrito, California);  Tevye Kuykendal (Berkeley, California);  Peter Pauzauskie (Berkeley, California)
ABSTRACT A method for is disclosed for fabricating diluted magnetic semiconductor (DMS) nanowires by providing a catalyst-coated substrate and subjecting at least a portion of the substrate to a semiconductor, and dopant via chloride-based vapor transport to synthesize the nanowires. Using this novel chloride-based chemical vapor transport process, single crystalline diluted magnetic semiconductor nanowires Ga1-xMnxN (x=0.07) were synthesized. The nanowires, which have diameters of ˜10 nm to 100 nm and lengths of up to tens of micrometers, show ferromagnetism with Curie temperature above room temperature, and magnetoresistance up to 250 Kelvin.
FILED Thursday, June 29, 2006
APPL NO 11/480280
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/478
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003852 Gaxiola et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) University of Connecticut (Farmington, Connecticut);  Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Roberto A. Gaxiola (Tempe, Arizona);  Gerald R. Fink (Chestnut Hill, Massachusetts);  Seth L. Alper (Boston, Massachusetts)
ABSTRACT Transgenic plants are described which are engineered to overexpress vacuolar H+-PPase. Plants such as tobacco and petunia transformed with A. Thaliana AVP-1 are shown to have increased meristematic activity resulting in larger leaves, stem, flower, fruit, root structures, increased salt tolerance, enhanced drought and freeze tolerance. Methods of making such plants are also described.
FILED Tuesday, March 31, 2009
APPL NO 12/384115
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003855 Somerville et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) Carnegie Institution of Washington (Washington, District of Columbia);  Monsanto Company, Inc. (St. Louis, Missouri)
INVENTOR(S) Chris Somerville (Portola Valley, California);  Pierre Broun (Burlingame, California);  Frank van de Loo (Weston, Australia);  Sekhar S. Boddupalli (Manchester, Michigan)
ABSTRACT This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.
FILED Thursday, September 27, 2007
APPL NO 11/905067
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/306
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004474 Makarov et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Physical Sciences, Inc. (Andover, Massachusetts)
INVENTOR(S) Sergey N. Makarov (Holden, Massachusetts);  Francesca Scire-Scappuzzo (Lexington, Massachusetts)
ABSTRACT Described is an apparatus and method for reducing noise in an information bearing signal is provided. A feeding element receives dual-polarized wideband electromagnetic signals. The feeding element is coupled to a Non-Cutoff Frequency Selective Surface ground plane. The Non-Cutoff Frequency Selective Surface ground plane allows for a line-of-sight signal and a surface wave to cancel. The Non-Cutoff Frequency Selective Surface ground plane can be a metal plate with a plurality of corrugations. The corrugations can be concentric rings, each corrugation having a predetermined height and a predetermined spacing from adjacent corrugations.
FILED Wednesday, September 17, 2008
APPL NO 12/212065
ART UNIT 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications: Radio wave antennas
343/909
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004762 Cathey, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Regents Of The University Of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Wade Thomas Cathey, Jr. (Boulder, Colorado);  Edward Raymond Dowski, Jr. (Lafayette, Colorado)
ABSTRACT Systems and methods for generating an optical image include forming an optical image with at least one optical element of an optical imager while modifying wavefront phase. Modifying the phase does not reduce an optical bandpass limited by an aperture of the optical imager. The systems and methods also include detecting the optical image over a range of spatial frequencies such that there are no zeros in an optical transfer function of the optical imager over detected spatial frequencies within the optical bandpass and over an extended depth of focus that is larger than a depth of focus occurring without modifying wavefront phase.
FILED Monday, October 13, 2008
APPL NO 12/250343
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/558
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005114 Mishra et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Arunesh Mishra (Mountain View, California);  Suman Banerjee (Madison, Wisconsin)
ABSTRACT A transceiver for wireless data transmission provides for variable bit rates within a packet (intra-packet rate changes) to provide a high-speed adaptation to variations in link quality useful for continuous mobility applications. Intra-packet rate variations may be obtained with standard hardware by remapping payload data to a subset of the hardware transmission constellation symbols.
FILED Tuesday, September 08, 2009
APPL NO 12/555353
ART UNIT 2474 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/472
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005332 Schmidt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Brigham Young University (Provo, Utah)
INVENTOR(S) Holger Schmidt (Capitola, California);  Aaron Roe Hawkins (Provo, Utah)
ABSTRACT An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate.
FILED Wednesday, April 02, 2008
APPL NO 12/061165
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/131
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005526 Martin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) David C. Martin (Ann Arbor, Michigan);  Sarah Richardson-Burns (Ypsilanti, Michigan);  Donghwan Kim (Ann Arbor, Michigan);  Jeffrey L. Hendricks (Ann Arbor, Michigan);  Laura Povlich (Taylor, Michigan);  Mohamad Reza Abidian (Ann Arbor, Michigan);  Matthew Meier (Ann Arbor, Michigan)
ABSTRACT Bioelectrodes having enhanced biocompatible and biomimetic features are provided. Methods of making and using the bioelectrodes are further provided. A biologically integrated bioelectrode device and method for detecting electronic signals using a bioelectrode comprising a first electrically conductive substrate and a biological component. The bioelectrode also comprises a conductive polymer electrically coupling the first electrically conductive substrate and the biological component to define a bioelectrode. The bioelectrode can transmit or receive an electrical signal between the electrically conductive substrate and the biological component and conductive polymer.
FILED Wednesday, August 30, 2006
APPL NO 11/512479
ART UNIT 3739 — Optics
CURRENT CPC
Surgery
6/372
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005975 Liu
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S)
ASSIGNEE(S) Polytechnic Institute of New York University (Brooklyn, New York)
INVENTOR(S) Yong Liu (Secaucus, New Jersey)
ABSTRACT A new P2P streaming method and apparatus disseminates video chunks to all peers with the minimum (or at least reduced) delay. After obtaining a new video chunk, a peer keeps transmitting (uploading) that video chunk to other peers until all peers receive it. The approach quickly increases the aggregate bandwidth that can be utilized to transmit a video chunk. For example, the aggregate peer bandwidth used to transmit a video chunk can double every time slot. For a homogeneous P2P streaming system with N peers, a time slot is defined as a unit of the single chunk transmission delay between two peers. Using the P2P streaming method, a video chunk can be disseminated to all peers within 1+log2 N time slots.
FILED Wednesday, October 06, 2010
APPL NO 12/898762
ART UNIT 2453 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/231
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 08001828 Hunter et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Gary W. Hunter (Oberlin, Ohio);  Jennifer C. Xu (Olmsted Township, Ohio);  Dorothy Lukco (Sagamore Hills, Ohio)
ABSTRACT A miniaturized Schottky diode hydrogen and hydrocarbon sensor and the method of making same is disclosed and claimed. The sensor comprises a catalytic metal layer, such as palladium, a silicon carbide substrate layer and a thin barrier layer in between the catalytic and substrate layers made of palladium oxide (PdOx ). This highly stable device provides sensitive gas detection at temperatures ranging from at least 450 to 600° C. The barrier layer prevents reactions between the catalytic metal layer and the substrate layer. Conventional semiconductor fabrication techniques are used to fabricate the small-sized sensors. The use of a thicker palladium oxide barrier layer for other semiconductor structures such as a capacitor and transistor structures is also disclosed.
FILED Friday, June 20, 2008
APPL NO 12/143139
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/31.60
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08002219 Camarda et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Charles J. Camarda (League City, Texas);  Stephen J. Scotti (Grafton, Virginia);  Pieter G. Buning (Yorktown, Virginia);  Steven X. S. Bauer (Yorktown, Virginia);  Walter C. Engelund (Seaford, Virginia);  David M. Schuster (Williamsburg, Virginia)
ABSTRACT An annular fairing having aerodynamic, thermal, structural and acoustic attributes couples a launch abort motor to a space vehicle having a payload of concern mounted on top of a rocket propulsion system. A first end of the annular fairing is fixedly attached to the launch abort motor while a second end of the annular fairing is attached in a releasable fashion to an aft region of the payload. The annular fairing increases in diameter between its first and second ends.
FILED Friday, November 16, 2007
APPL NO 11/941119
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/171.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003055 Muradov
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Nazim Muradov (Melbourne, Florida)
ABSTRACT Methods, processes and compositions are provided for a visual or chemochromic hydrogen-detector with variable or tunable reversible color change. The working temperature range for the hydrogen detector is from minus 100° C. to plus 500° C. A hydrogen-sensitive pigment, including, but not limited to, oxides, hydroxides and polyoxo-compounds of tungsten, molybdenum, vanadium, chromium and combinations thereof, is combined with nano-sized metal activator particles and preferably, coated on a porous or woven substrate. In the presence of hydrogen, the composition rapidly changes its color from white or light-gray or light-tan to dark gray, navy-blue or black depending on the exposure time and hydrogen concentration in the medium. After hydrogen exposure ceases, the original color of the hydrogen-sensitive pigment is restored, and the visual hydrogen detector can be used repeatedly. By changing the composition of the hydrogen-sensitive pigment, the time required for its complete regeneration is varied from a few seconds to several days.
FILED Wednesday, February 27, 2008
APPL NO 12/038210
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/86
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004364 Sims, III et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) William Herbert Sims, III (New Market, Alabama);  Donald Gregory Chavers (Somerville, Alabama);  James J. Richeson (Madison, Alabama)
ABSTRACT A high power, high frequency, solid state power amplifier system includes a plurality of input multiple port splitters for receiving a high-frequency input and for dividing the input into a plurality of outputs and a plurality of solid state amplifier units. Each amplifier unit includes a plurality of amplifiers, and each amplifier is individually connected to one of the outputs of multiport splitters and produces a corresponding amplified output. A plurality of multiport combiners combine the amplified outputs of the amplifiers of each of the amplifier units to a combined output. Automatic level control protection circuitry protects the amplifiers and maintains a substantial constant amplifier power output.
FILED Thursday, July 26, 2007
APPL NO 11/828563
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Amplifiers
330/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004558 Prechtl et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S)
ASSIGNEE(S) Axis Engineering Technologies, Inc. (Devens, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Eric F. Prechtl (Groton, Massachusetts);  Raymond J. Sedwick (Somerville, Massachusetts);  Eric M. Jonas (Cambridge, Massachusetts)
ABSTRACT A stereoscopic imaging system incorporates a plurality of imaging devices or cameras to generate a high resolution, wide field of view image database from which images can be combined in real time to provide wide field of view or panoramic or omni-directional still or video images.
FILED Friday, April 07, 2006
APPL NO 11/400029
ART UNIT 2622 — Selective Visual Display Systems
CURRENT CPC
Television
348/48
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005314 Ortyn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Aeronautics and Space Administration (NASA)
Ames Research Center (ARC)
APPLICANT(S)
ASSIGNEE(S) Amnis Corporation (Seattle, Washington)
INVENTOR(S) William Ortyn (Bainbridge Island, Washington);  David Basiji (Seattle, Washington);  Keith Frost (Seattle, Washington);  Luchuan Liang (Woodinville, Washington);  Richard Bauer (Kirkland, Washington);  Brian Hall (Seattle, Washington);  David Perry (Woodinville, Washington)
ABSTRACT A high speed, high-resolution flow imaging system is modified to achieve extended depth of field imaging. An optical distortion element is introduced into the flow imaging system. Light from an object, such as a cell, is distorted by the distortion element, such that a point spread function (PSF) of the imaging system is invariant across an extended depth of field. The distorted light is spectrally dispersed, and the dispersed light is used to simultaneously generate a plurality of images. The images are detected, and image processing is used to enhance the detected images by compensating for the distortion, to achieve extended depth of field images of the object. The post image processing preferably involves de-convolution, and requires knowledge of the PSF of the imaging system, as modified by the optical distortion element.
FILED Monday, December 11, 2006
APPL NO 11/609269
ART UNIT 2447 — Computer Networks
CURRENT CPC
Image analysis
382/275
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 08002919 Johnson et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Ebert Composites Corporation (Chula Vista, California)
INVENTOR(S) David W. Johnson (San Diego, California);  Scott A. Garrett (San Diego, California);  James H. Hook (Alpine, California);  Stephen G. Moyers (Jamul, California)
ABSTRACT A method of inserting z-axis reinforcing fibers into a multi-layer composite laminate. Layers of material made up of z-axis fiber and y-axis fibers are automatically transported into a z-fiber deposition machine having a housing with upper and lower surfaces. Z-axis apertures are formed in the respective upper and lower surfaces. An elongated solid rod having a tapered front tip is aligned in close proximity to the aperture in the bottom surface. The rod is first rotated by a motor and then actuated upwardly completely through the thickness of the layer of x-y material by an actuator. A first hollow tube having a z-axis is axially aligned with the aperture in the top surface and a fiber bundle is threaded downwardly through a first hollow tube to a position adjacent its bottom end. The z-fiber deposition machine has structure to feed a predetermined length of the fiber bundle downwardly through the first hollow tube so that it follows the pathway in the x-y material formed by the rod which is now withdrawn downwardly through the aperture in the bottom wall. The z-axis fiber is thus deposited into the x-y material. The top end of the z-axis fiber is then severed and the x-y material is then advanced a predetermined distance to complete the cycle and is, thus, set to be repeated.
FILED Monday, June 16, 2008
APPL NO 12/140121
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/91
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003051 Bedingham et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) William Bedingham (Woodbury, Minnesota);  James E. Aysta (Stillwater, Minnesota);  Barry W. Robole (Woodville, Wisconsin)
ABSTRACT Sample processing systems for processing sample materials located in sample processing devices that are separate from the system are disclosed. The sample processing systems include a rotating base plate with raised and/or non-planar thermal structures on which the sample processing devices are located during operation of the systems. The systems may also include structure to urge the sample processing devices against the base plate and thermal structures.
FILED Thursday, June 25, 2009
APPL NO 12/491959
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/64
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003769 Fisher et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Applied Biosystems, LLC (Carlsbad, California)
INVENTOR(S) Peter Virgil Fisher (El Granada, California);  Shaheer Khan (Foster City, California);  Paolo Vatta (San Mateo, California)
ABSTRACT The invention provides novel dye-labeled ribonucleotide analogs and methods for synthesizing those analogs. The compounds of the invention are especially useful for DNA sequencing by the polymerase chain reaction.
FILED Monday, January 25, 2010
APPL NO 12/656305
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/4.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003807 Li et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Xerox Corporation (Norwalk, Connecticut)
INVENTOR(S) Yuning Li (Mississauga, Canada);  Beng S. Ong (Mississauga, Canada);  Yiliang Wu (Mississauga, Canada);  Ping Liu (Mississauga, Canada)
ABSTRACT An electronic device including a compound comprising at least one type of an optionally substituted indolocarbazole moiety and at least one divalent linkage.
FILED Wednesday, June 02, 2010
APPL NO 12/791928
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/416
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003926 Bedingham et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) William Bedingham (Woodbury, Minnesota);  Raj Rajagopal (Woodbury, Minnesota);  Barry W. Robole (Woodinville, Wisconsin)
ABSTRACT Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is rotated during heating of the sample materials.
FILED Friday, September 05, 2008
APPL NO 12/205170
ART UNIT 3742 — Organic Chemistry
CURRENT CPC
Electric heating
219/627
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 08003136 Beavers
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Randy Beavers (Dalton, Georgia)
ABSTRACT The present invention relates generally to herbal materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. Particularly, the present invention relates generally to Hydrastis canadensis (goldenseal) materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. More particularly, the present invention relates a process which allows the standardization of the product to specified levels of bioactivity in both hydro-alcoholic tinctures and solid extracts in the processing of goldenseal materials to produce extracts which qualify as pharmaceutical grade compositions which are suitable for use in clinical or veterinary settings to treat and/or ameliorate diseases, disorders or conditions.
FILED Tuesday, July 31, 2007
APPL NO 11/882270
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/725
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003328 Rosenkrans, Jr.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S) Charles F. Rosenkrans, Jr. (Springdale, Arkansas)
ABSTRACT Methods of predicting the phenotype of a trait in a bovine subject are provided. The methods include obtaining information about polynucleotide sequences specifically regarding the identity of the nucleotides present at one or more identified single nucleotide polymorphisms and using this information to make predictions regarding the trait in the subject. Also provided are kits for and methods of determining the nucleotide present in a bovine subject at a position in which a single nucleotide polymorphism is correlated with a trait.
FILED Monday, February 02, 2009
APPL NO 12/364145
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08004292 Backus et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Elaine Backus (Clovis, California);  William Bennett (Otterville, Missouri)
ABSTRACT An electrical penetration graph (EPG) system includes a monitoring device with a buffered and stabilized voltage source assembly and a buffered internal amplifier with switched gain control. The system also includes a head stage amplifier. During the EPG process, the voltage source assembly directs an electrical current through a feeding insect. As the current passes through the insect, the insect's feeding process modulates the current and creates voltage waveform data. A head stage amplifier with selectable input resistance receives and amplifies the voltage waveform data. The data is transmitted back to the monitoring device where it is manipulated and further amplified by the monitoring device internal amplifier assembly. The waveform data is then transmitted to a controller and ultimately to an output device where the data is displayed.
FILED Wednesday, October 22, 2008
APPL NO 12/256168
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/692
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 08002874 Huang et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Membrane Technology and Research, Inc. (Menlo Park, California)
INVENTOR(S) Yu Huang (Palo Alto, California);  Jennifer Ly (San Jose, California);  Tiem Aldajani (San Jose, California);  Richard W. Baker (Palo Alto, California)
ABSTRACT Processes for dehydrating an organic/water solution by pervaporation or vapor separation using fluorinated membranes. The processes are particularly useful for treating mixtures containing light organic components, such as ethanol, isopropanol or acetic acid.
FILED Tuesday, March 06, 2007
APPL NO 11/715245
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Gas separation: Processes
095/50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003136 Beavers
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Randy Beavers (Dalton, Georgia)
ABSTRACT The present invention relates generally to herbal materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. Particularly, the present invention relates generally to Hydrastis canadensis (goldenseal) materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. More particularly, the present invention relates a process which allows the standardization of the product to specified levels of bioactivity in both hydro-alcoholic tinctures and solid extracts in the processing of goldenseal materials to produce extracts which qualify as pharmaceutical grade compositions which are suitable for use in clinical or veterinary settings to treat and/or ameliorate diseases, disorders or conditions.
FILED Tuesday, July 31, 2007
APPL NO 11/882270
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/725
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005527 Zelenchuk
FUNDED BY
Department of Health and Human Services (HHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Luma Imaging Corporation (San Diego, California)
INVENTOR(S) Alex R. Zelenchuk (Stoughton, Massachusetts)
ABSTRACT A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, one of which corresponds to an isosbestic point. In one example, the isosbestic point occurs at about 431 nm. The intensities of the observed signals are normalized using the 431 nm intensity. A score is determined using the ratios in a discriminant analysis. The tissue under examination is resected or not, based on the diagnosis of disease or health, according to the outcome of the discriminant analysis.
FILED Wednesday, December 12, 2007
APPL NO 11/955165
ART UNIT 3737 — Optics
CURRENT CPC
Surgery
6/407
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 08003385 Sukumar et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
Department of the Interior (DOI)
APPLICANT(S)
ASSIGNEE(S) Sanofi Pasteur Vax Design Corp. (Orlando, Florida)
INVENTOR(S) Selva Sukumar (Berkeley, California);  Mohey Eldin M. El Shikh (Richmond, Virginia);  John G. Tew (Mechanicsville, Virginia);  Guzman Sanchez-Schmitz (Orlando, Florida);  Donald Drake, III (Orlando, Florida);  Luis Mosquera (Oviedo, Florida);  Conan Li (Los Altos, California);  Anatoly M. Kachurin (Orlando, Florida);  Russell Higbee (Orlando, Florida);  Heather Fahlenkamp (Cleveland, Oklahoma);  Eric Mishkin (Winter Springs, Florida);  William L. Warren (Orlando, Florida)
ABSTRACT The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
FILED Wednesday, February 17, 2010
APPL NO 12/707563
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003387 Sukumar et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
Department of the Interior (DOI)
APPLICANT(S)
ASSIGNEE(S) Sanofi Pasteur Vaxdesign Corp. (Orlando, Florida)
INVENTOR(S) Selva Sukumar (Berkeley, California);  Mohey Eldin M. El Shikh (Richmond, Virginia);  John G. Tew (Mechanicsville, Virginia);  Guzman Sanchez-Schmitz (Orlando, Florida);  Donald Drake, III (Orlando, Florida);  Luis Mosquera (Oviedo, Florida);  Eric Mishkin (Winter Springs, Florida);  Anatoly M. Kachurin (Orlando, Florida);  Russell Higbee (Orlando, Florida);  Conan Li (Los Altos, California);  William L. Warren (Orlando, Florida);  Heather Fahlenkamp (Cleveland, Oklahoma)
ABSTRACT The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
FILED Thursday, December 21, 2006
APPL NO 11/642938
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/373
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08003937 Kertesz et al.
FUNDED BY
Department of Energy (DOE)
National Security Agency (NSA)
Center for Communications and Computing (CC) at Alexandria, VA
Federally Funded Research and Development Center (FFRDC)
Operated by Institute for Defense Analyses (IDA) at Alexandria, VA
APPLICANT(S)
ASSIGNEE(S) UT-Battelle (Oak Ridge, Tennessee)
INVENTOR(S) Vilmos Kertesz (Knoxville, Tennessee);  Gary Van Berkel (Clinton, Tennessee)
ABSTRACT An electrospray ion (ESI) source and method capable of ionizing an analyte molecule without oxidizing or reducing the analyte of interest. The ESI source can include an emitter having a liquid conduit, a working electrode having a liquid contacting surface, a spray tip, a secondary working electrode, and a charge storage coating covering partially or fully the liquid contacting surface of the working electrode. The liquid conduit, the working electrode and the secondary working electrode can be in liquid communication. The electrospray ion source can also include a counter electrode proximate to, but separated from, said spray tip. The electrospray ion source can also include a power system for applying a voltage difference between the working electrodes and a counter-electrode. The power system can deliver pulsed voltage changes to the working electrodes during operation of said electrospray ion source to minimize the surface potential of the charge storage coating.
FILED Thursday, September 25, 2008
APPL NO 12/237892
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/288
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08005839 Aggarwal et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charu C. Aggarwal (Mohegan Lake, New York);  Philip Shi-Lung Yu (Chicago, Illinois)
ABSTRACT Techniques are disclosed for aggregation in uncertain data in data processing systems. For example, a method of aggregation in an application that involves an uncertain data set includes the following steps. The uncertain data set along with uncertainty information is obtained. One or more clusters of data points are constructed from the data set. Aggregate statistics of the one or more clusters and uncertainty information are stored. The data set may be data from a data stream. It is realized that the use of even modest uncertainty information during an application such as a data mining process is sufficient to greatly improve the quality of the underlying results.
FILED Thursday, February 28, 2008
APPL NO 12/039076
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/737
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 08003324 Dudley, Jr.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) U.S. Department of Veterans Affairs (Washington, District of Columbia);  Emory University (Atlanta, Georgia)
INVENTOR(S) Samuel C. Dudley, Jr. (Chicago, Illinois)
ABSTRACT The present invention relates to the use of oxidized nicotinamide adenine dinucleotide (NAD+) or of its reduced form, NADH, as sodium channel modulators. The present invention also relates to the use of compositions containing NAD+ or NADH to treat conditions associated with sodium channel current, such as arrhythmia. NAD+ is found to increase sodium channel current, while NADH is found to decrease sodium channel current. Thus, conditions that are associated with decreased sodium channel current can be treated with NAD+, while conditions that is associated with increased sodium channel current can be treated with NADH.
FILED Friday, October 17, 2008
APPL NO 12/289005
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 08005568 Hamilton
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Daryl Hamilton (Hyattsville, Maryland)
ABSTRACT A method of tracking trays through a delivery system. The method comprises: generating an enhanced label, the enhanced label comprising a routing code and a label unique identifier, the enhanced label being applied to the tray; associating a tray with a container, the container having a container unique identifier; and receiving a load container scan, the load container scan associating the container unique identifier with the enhanced label.
FILED Friday, April 02, 2004
APPL NO 10/817574
ART UNIT 3627 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Generic control systems or specific applications
7/225
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08001826 Schwarz et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Dwight Schwarz (Sahuarita, Arizona);  Mark J. Kocan (Tucson, Arizona)
ABSTRACT An impact testing system for determining the shock response of a test structure includes a mass (e.g., a spherical steel ball) and a potential energy storage system (e.g., a spring-loaded mechanism) configured to store mechanical energy and, upon actuation, release the stored mechanical energy in the form of kinetic energy. A hold-and-release mechanism (such as a permanent magnet) is configured to releasably couple the mass to the potential energy storage system and impart linear momentum to the mass in connection with the kinetic energy such that the mass impinges upon the test structure. The shock response can then be determined and displayed to a user.
FILED Tuesday, May 26, 2009
APPL NO 12/472124
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/12.50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08003778 Paul et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) John H. Paul (St. Petersburg, Florida);  Mike Gray (St. Petersburg, Florida);  Erica Casper (St. Petersburg, Florida)
ABSTRACT A real-time reverse transcription-PCR, or NABSA, method (and associated primers) targeting the rbcL gene for the detection and quantitation of the Florida red tide organism, Karenia brevis.
FILED Tuesday, March 16, 2010
APPL NO 12/724854
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.300
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, August 23, 2011.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2011/fedinvent-patents-20110823.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital