FedInvent™ Patents
Patent Details for Tuesday, August 23, 2011
This page was updated on Monday, March 27, 2023 at 02:03 AM GMT
Department of Health and Human Services (HHS)
US 08001876 | Tabb et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | SAIC-Frederick, Inc. (Frederick, Maryland) |
INVENTOR(S) | Brian Carroll Tabb (Cumberland, Maryland); Keith Rogers (Singapore, Singapore) |
ABSTRACT | Systems and methods described herein for aligning a block in a microtome attempt to save time, money, and the sample by aligning a block in any rotary or cryostat microtome. One such device for aligning a block in a microtome has a knife holder component removably attached to a knife holder of the microtome and a pin alignment component extending vertically from the knife holder component in a direction substantially parallel to the block. The pin alignment component has a plurality of front pins extending from a front surface of the pin alignment component configured to slide in response to an angle of the block and a plurality of rear pins extending from a rear surface of the pin alignment component and coupled to the front pins. The rear pins are configured to indicate the extension of the front pins from the pin alignment component. |
FILED | Wednesday, May 14, 2008 |
APPL NO | 12/153110 |
ART UNIT | 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Cutting 083/522.150 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002933 | Unger et al. |
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ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Marc A. Unger (South San Francisco, California); Hou-Pu Chou (Pasadena, California); Todd A. Thorsen (Pasadena, California); Axel Scherer (Laguna Beach, California); Stephen R. Quake (San Marino, California) |
ABSTRACT | A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate. |
FILED | Friday, November 02, 2007 |
APPL NO | 11/934235 |
ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/242 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003078 | Lanza et al. |
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ASSIGNEE(S) | Barnes-Jewish Hospital (St. Louis, Missouri) |
INVENTOR(S) | Gregory M. Lanza (St. Louis, Missouri); Samuel A. Wickline (St. Louis, Missouri); Garry E. Kiefer (Richardson, Texas); Phillip S. Athey (Lake Jackson, Texas) |
ABSTRACT | MRI contrast agents that employ paramagnetic agents and chemical exchange saturation transfer (paraCEST) and which are coupled to targeted particulate delivery vehicles provide sufficient concentration of the paraCEST contrast agents to obtain useful images of target tissues or organs. In addition, the image contrast may be switched on or off with a presaturation radio frequency pulse, avoiding the necessity obtaining pre-injection and post-injection images. |
FILED | Thursday, March 29, 2007 |
APPL NO | 11/693647 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.365 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003112 | Tai et al. |
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ASSIGNEE(S) | Howard University (Washington, District of Columbia); The United States of America as represented by the Secretary, Department of Health and Human Services; National Institutes of Health, Office of Technology Transfer (Washington, District of Columbia) |
INVENTOR(S) | Stanley Shih-Peng Tai (Rockville, Maryland); Che-Hung Robert Lee (Silver Spring, Maryland) |
ABSTRACT | This disclosure relates to vaccine formulations comprising an immunogenic composition for inducing antibodies to both S. pneumoniae and N. meningitides in a subject. In a preferred aspect, the immunogenic composition comprises covalently conjugated recombinant PsaA (“rPsaA”) from S. pneumoniae and capsular polysaccharide from N. meningitidis serogroup C. This disclosure further relates to methods for producing the immunogenic composition as well as methods for their use. |
FILED | Thursday, April 16, 2009 |
APPL NO | 12/425232 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/197.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003113 | Narayan et al. |
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INVENTOR(S) | Opendra Narayan (Lenexa, Kansas); Zhenqian Liu (Lenexa, Kansas) |
ABSTRACT | The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for used as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3′ LTR. |
FILED | Monday, February 09, 2009 |
APPL NO | 12/368151 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/208.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003129 | Hoffman et al. |
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ASSIGNEE(S) | University of Washington (Seattle, Washington); Univeristy of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Allan S. Hoffman (Seattle, Washington); Patrick Stayton (Seattle, Washington); Oliver W. Press (Seattle, Washington); Niren Murthy (Atlanta, Georgia); Chantal Lackey Reed (Del Mar, California); Lawrence A. Crum (Bellevue, Washington); Pierre D. Mourad (Seattle, Washington); Tyrone M. Porter (Boston, Massachusetts); David Tirrell (Pasadena, California) |
ABSTRACT | Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are described. The compositions include a membrane barrier transport enhancing agent and are usually administered in combination with an enhancer and/or exposure to stimuli to effect disruption or altered permeability, transport or release. In a preferred embodiment, the compositions include compounds which disrupt endosomal membranes in response to the low pH in the endosomes but which are relatively inactive toward cell membranes, coupled directly or indirectly to a therapeutic or diagnostic agent. Other disruptive agents can also be used, responsive to stimuli and/or enhancers other than pH, such as light, electrical stimuli, electromagnetic stimuli, ultrasound, temperature, or combinations thereof. The compounds can be coupled by ionic, covalent or H bonds to an agent to be delivered or to a ligand which forms a complex with the agent to be delivered. Agents to be delivered can be therapeutic and/or diagnostic agents. Treatments which enhance delivery such as ultrasound, iontophoresis, and/or electrophoresis can also be used with the disrupting agents. |
FILED | Friday, April 18, 2008 |
APPL NO | 12/105983 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/501 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003131 | Badylak |
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ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Stephen F. Badylak (Pittsburgh, Pennsylvania) |
ABSTRACT | A tissue graft composition comprising liver basement membrane is described. The graft composition can be implanted to replace or induce the repair of damaged or diseased tissues. |
FILED | Tuesday, January 06, 2009 |
APPL NO | 12/349254 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/553 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003312 | Krutzik et al. |
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ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Peter O. Krutzik (Los Altos, California); Garry Nolan (San Francisco, California) |
ABSTRACT | We describe herein a cell-based multiplexing technique called detectable cell barcoding (DCB). In DCB, each individual sample is labeled with a different DCB signature that distinguishes each sample by one or both of detected intensity or type of detection characteristic. The samples are then combined and analyzed for a detectable characteristic of interest (e.g., presence of an analyte). By employing multiple distinct DCB labels at varying concentrations, one can perform multiplex analyses on up to hundreds or thousands (or more) of cell samples in a single reaction tube. DCB reduces reagent consumption by factors of 100-fold or more, significantly reduces data acquisition times and allows for stringent control sample analysis. |
FILED | Thursday, February 14, 2008 |
APPL NO | 12/031499 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003324 | Dudley, Jr. |
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ASSIGNEE(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia); Emory University (Atlanta, Georgia) |
INVENTOR(S) | Samuel C. Dudley, Jr. (Chicago, Illinois) |
ABSTRACT | The present invention relates to the use of oxidized nicotinamide adenine dinucleotide (NAD+) or of its reduced form, NADH, as sodium channel modulators. The present invention also relates to the use of compositions containing NAD+ or NADH to treat conditions associated with sodium channel current, such as arrhythmia. NAD+ is found to increase sodium channel current, while NADH is found to decrease sodium channel current. Thus, conditions that are associated with decreased sodium channel current can be treated with NAD+, while conditions that is associated with increased sodium channel current can be treated with NADH. |
FILED | Friday, October 17, 2008 |
APPL NO | 12/289005 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003325 | Ansell et al. |
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ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Stephen M. Ansell (Rochester, Minnesota); Anne J. Novak (Oronoco, Minnesota) |
ABSTRACT | The present invention provides an isolated polynucleotide comprising at least one polymorphic nucleotide sequence, for example, the major alleles of the SNPs described as rs12583006, rs1224141, and rs1248930 and diagnostic assays for detecting the presence of these polymorphism associated with a condition associated with BLyS activity, such as hematological malignancy including B cell malignancies. The diagnostic assays are useful in predicting an individual's likelihood of developing a condition associated with BLyS activity, such as hematological malignancies, and for methods for treating an individual clinically diagnosed with a condition associated with BLyS activity, such as prediction of a patient's likelihood to respond to a specific drug treatment. The invention also provides an array of nucleic acid molecules immobilized on a solid surface, where at least one of the nucleic acid molecules comprises a BLyS polymorphic nucleic acid molecule. The nucleic acid arrays of the invention allow rapid detection of hybridizing nucleic acid-molecules, in a nucleic acid sample from an individual, of a BLyS polymorphism associated with hematological malignancy. |
FILED | Wednesday, November 26, 2008 |
APPL NO | 12/323861 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003327 | Boustany et al. |
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ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Rose-Mary N. Boustany (Durham, North Carolina); Wei-Xing Guo (Northridge, California); Andrea Amalfitano (Durham, North Carolina) |
ABSTRACT | A method of screening a subject for a proliferative disease risk factor comprises detecting the presence or absence of upregulation of the CLN3 gene in the subject. The upregulation of the CLN3 gene in the subject indicates the subject is at increased risk of developing a proliferative disease. Methods of screening compounds for the treatment of proliferative diseases based on the CLN3 gene and its product are also disclosed, along with methods of treating such diseases and vectors useful therefore. |
FILED | Thursday, January 22, 2009 |
APPL NO | 12/357750 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003332 | Kielian et al. |
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ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
INVENTOR(S) | Margaret Kielian (Pelham, New York); Maofu Liao (San Francisco, California) |
ABSTRACT | Methods of inhibiting viral infection of a eukaryotic cell by a target virus having a class II virus fusion protein are provided. Also provided are methods of screening a test compound for the ability to inhibit infection by a virus having a class II viral fusion protein. Additionally provided herewith are aqueous-soluble proteins comprising a portion of a class II viral fusion protein comprising a Domain III of the viral fusion protein. |
FILED | Thursday, May 04, 2006 |
APPL NO | 11/918835 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003342 | Brown et al. |
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ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Michael S. Brown (Dallas, Texas); Joseph L. Goldstein (Dallas, Texas); Yuval Reiss (Dallas, Texas) |
ABSTRACT | Disclosed are methods and compositions for the identification of inhibitors of farnesyl protein transferases, enzymes involved in the farnesylation of various cellular proteins, including cancer related ras proteins such as p21ras. One farnesyl protein transferase which is disclosed herein exhibits a molecular weight of between about 70,000 and about 100,000 upon gel exclusion chromatography. The enzyme appears to comprise one or two subunits of approximately 50 kDa each. Methods are disclosed for assay and purification of the enzyme, as well as procedures for using the purified enzyme in screening protocols for the identification of possible anticancer agents which inhibit the enzyme and thereby prevent expression of proteins such as p21ras. Also disclosed is a families of compounds which act either as false substrates for the enzyme or as pure inhibitors and can therefore be employed for inhibition of the enzyme. The most potent inhibitors are ones in which phenylalanine occurs at the third position of a tetrapeptide whose amino terminus is cysteine. |
FILED | Thursday, April 18, 1991 |
APPL NO | 07/937893 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003354 | Shen et al. |
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ASSIGNEE(S) | Illumina, Inc. (San Diego, California) |
INVENTOR(S) | Min-Jui Richard Shen (San Diego, California); Arnold Oliphant (Poway, California); Scott L. Butler (San Diego, California); John R. Stuelpnagel (Encinitas, California); Mark S. Chee (Del Mar, California); Kenneth M. Kuhn (San Diego, California); Jian-Bing Fan (San Diego, California) |
ABSTRACT | The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously. |
FILED | Friday, February 15, 2008 |
APPL NO | 12/032581 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003374 | Heeger et al. |
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ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alan J. Heeger (Santa Barbara, California); Chunhai Fan (Shanghai, China PRC); Kevin Plaxco (Santa Barbara, California) |
ABSTRACT | A reagentless, reusable bioelectronic DNA, or other oligonucleotide sequence sensor is disclosed. The sensor includes an oligonucleotide (aptamer) probe tagged with a electroactive, redoxable moiety, self-assembled on or near an electrode. This surface-confined oligonucleotide (aptamer) probe structure undergoes hybridization-induced conformational change in the presence of the target which changes the electron-transfer distance between the redoxable moiety and the electrode thereby providing a detectable signal change. In an alternative embodiment, the target can harbor the redoxable moiety. |
FILED | Friday, July 29, 2005 |
APPL NO | 11/193318 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003378 | Wikswo et al. |
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ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Franz J. Baudenbacher (Franklin, Tennessee); Ales Prokop (Nashville, Tennessee); Eugene LeBoeuf (Franklin, Tennessee); Chang Y. Chung (Franklin, Tennessee); David E. Cliffel (Nashville, Tennessee); Frederick R. Haselton (Nashville, Tennessee); William H. Hofmeister (Nashville, Tennessee); Charles P. Lin (Brentwood, Tennessee); Lisa J. McCawley (Nashville, Tennessee); Randall S. Reiserer (Nashville, Tennessee); Mark A. Stremler (Franklin, Tennessee) |
ABSTRACT | A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel. |
FILED | Thursday, March 05, 2009 |
APPL NO | 12/398825 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/289.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003384 | Matsunami et al. |
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ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Hiroaki Matsunami (Durham, North Carolina); Momoka Matsunami (Durham, North Carolina); Yoshiro Ishimaru (Tokyo, Japan) |
ABSTRACT | The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo. |
FILED | Monday, December 07, 2009 |
APPL NO | 12/632299 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003388 | Neumann |
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ASSIGNEE(S) | Nortis, Inc. (Gig Harbor, Washington) |
INVENTOR(S) | Thomas Neumann (Seattle, Washington) |
ABSTRACT | A method for creating networks of perfusable microvessels in vitro. A mandrel is drawn through a matrix to form a channel through the matrix. Cells are injected into the channel. The matrix is incubated to allow the cells to attach inside the channel. The channel is perfused to remove unattached cells to create a parent vessel, where the parent vessel includes a perfusable hollow channel lined with cells in the matrix. The parent vessel is induced to create sprouts into the surrounding matrix gel so as to form a microvessel network. The microvessel network is subjected to luminal perfusion through the parent vessel. |
FILED | Monday, September 24, 2007 |
APPL NO | 11/860471 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/395 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003390 | Donohue et al. |
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ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Timothy J. Donohue (Milddleton, Wisconsin); Jennifer Rachel Anthony (San Lorenzo, California); Kristin L. Warczak (Franklin, Wisconsin); Yann Dufour (Madison, Wisconsin); Heather Green (Madison, Wisconsin) |
ABSTRACT | The physiological response of a phototroph to singlet oxygen is altered by modulating the interaction between an anti-sigma factor, ChrR, and a sigma factor, σE, or by altering expression of a gene product required for viability in the presence of singlet oxygen. |
FILED | Tuesday, April 25, 2006 |
APPL NO | 11/410431 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/471 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003404 | Rotello et al. |
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ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Vincent Rotello (Belchertown, Massachusetts); Uwe Bunz (Atlanta, Georgia); Ronnie Phillips (Atlanta, Georgia); Oscar Miranda (Amherst, Massachusetts); Chang-Cheng You (Waltham, Massachusetts) |
ABSTRACT | Compositions, methods and related apparatus, as can be used for selective pathogen detection and identification. |
FILED | Monday, November 17, 2008 |
APPL NO | 12/313137 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003406 | Muenke et al. |
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ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Maximilian Muenke (Bala Cynwyd, Pennsylvania); Mauricio Arcos-Burgos (Rockville, Maryland); F. Xavier Castellanos (New York, New York) |
ABSTRACT | The invention provides a method of determining a susceptibility of a subject for development of ADHD. The method comprises obtaining a sample from the subject, analyzing the sample for an ADHD susceptibility haplotype of LPHN3 receptor which is associated with at least one genetic marker selected from the group consisting of rs7678046, rs1901223, rs6813183, and rs1355368, and determining if the subject has a susceptibility to develop ADHD, whereby the presence of the haplotype having one or more of the genetic markers is indicative of a susceptibility to develop ADHD. The invention also provides methods of treating ADHD. |
FILED | Thursday, September 27, 2007 |
APPL NO | 12/444898 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/504 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003572 | Banerjee |
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APPLICANT(S) | |
ASSIGNEE(S) | Amit Banerjee (Grosse Pointe, Michigan) |
INVENTOR(S) | Amit Banerjee (Grosse Pointe, Michigan) |
ABSTRACT | The present invention provides methods for identifying compounds that selectively bind one or more active sites within an ubiquitin conjugating enzyme. The compounds identified by the methods are useful in the treatment of disorders attributed to dysregulated ubiquitin conjugating enzyme function, specifically in hyperproliferative disorders. |
FILED | Thursday, December 28, 2006 |
APPL NO | 11/647788 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/8 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003606 | Patti et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Mary Elizabeth Patti (Newton, Massachusetts); Wanzhu Jin (Brookline, Massachusetts); Allison B. Goldfine (Wayland, Massachusetts) |
ABSTRACT | Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment. |
FILED | Friday, June 05, 2009 |
APPL NO | 12/479390 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/5.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003613 | Cance et al. |
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ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | William G. Cance (Orchard Park, New York); Vita Golubovskaya (Orchard Park, New York); Elena V. Kurenova (West Falls, New York) |
ABSTRACT | The C-terminal domain of focal adhesion kinase (FAK-CD) was isolated using a Baculoviral system. Using phage display techniques, a phage encoding a 12 amino-acid peptide (peptide 35) and AV3 that binds to FAK-CD were identified. The peptides were also conjugated to TAT-FITC to produce a fluorescently labeled chimeric molecule capable of penetrating cell membranes. Contacting various breast cancer cell lines with these molecule caused detachment, rounding, apoptosis and cell death. These effects were not observed in normal (non-cancerous) breast cells. |
FILED | Wednesday, November 17, 2004 |
APPL NO | 10/579529 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/18.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003618 | Marban et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Eduardo Marban (Beverly Hills, California); Mitsushige Murata (Tokyo, Japan) |
ABSTRACT | Disclosed is an invention for focally modulating the activity of a calcium channel in a mammal. In one aspect, the invention features a method that includes contacting a pre-determined tissue or organ region with a nucleic acid sequence encoding a GEM protein or a variant thereof to express the GEM protein or variant within the region. Typical methods further include expressing the GEM protein or variant so as to modulate the activity of the calcium channel. The invention has a wide spectrum of useful applications including treating a medical condition associated with unsuitable calcium channel activity. |
FILED | Thursday, October 02, 2003 |
APPL NO | 10/678723 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003622 | Wolfe et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Darren Wolfe (Pittsburgh, Pennsylvania); Joseph C. Glorioso (Pittsburgh, Pennsylvania); Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Darren P. Wolfe (Pittsburgh, Pennsylvania); Joseph C. Glorioso (Pittsburgh, Pennsylvania); David J. Fink (Ann Arbor, Michigan) |
ABSTRACT | The invention provides an expression cassette comprising a DNA sequence encoding amino acids 1-99 of human preproenkephalin, a DNA sequence encoding a precursor of a carboxy-amidated peptide flanked by dibasic cleavage sites and optionally a DNA sequence encoding a marker protein (such as Enhanced Green Fluorescent Protein (GFP)) all in operable linkage and under control of a promoter. Where the encoded precursor of a carboxy-amidated peptide is an agonist for an opioid receptor, the invention further provides a method of treating neuropathic pain by administering the gene transfer vector comprising such an expression cassette to a patient. The invention also provides a method for detecting a peptide having a desired effect comprising introducing a library of DNA sequences encoding one or more precursors of carboxy-amidated peptides into host cells; expressing the carboxy-amidated peptides encoded in the library to provide expression products; and screening from the polypeptide expression products for the desired effect. |
FILED | Wednesday, September 29, 2010 |
APPL NO | 12/893255 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003628 | Greene et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Mark I Greene (Penn Valley, Pennsylvania); Ramachandran Murali (Swarthmore, Pennsylvania); Masahiko Kinosaki (Tochigi, Japan) |
ABSTRACT | Methods of inhibiting osteoclastogenesis and the activity of osteoclasts are disclosed. Methods of treating patients who have diseases characterized bone loss are disclosed. According to the methods, an amount of a TRANCE/RANK inhibitor effective to inhibit osteoclastogenesis is administered to the patient. Pharmaceutical compositions which comprise TRANCE/RANK inhibitor in an amount effective to inhibit osteoclastogenesis. Methods of modulating dendritic cell maturation, T cell proliferation, and/or CD40 receptor systems in an individual are disclosed. The methods comprise the step of administering to the individual an amount of a TRANCE/RANK inhibitor effective to modulating dendritic cell maturation, T cell proliferation, and/or CD40 receptor systems. |
FILED | Monday, June 22, 2009 |
APPL NO | 12/488868 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/175 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003629 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Hyun K. Kim (Bellingham, Washington); Richard P. Blye (Highland, Maryland); Pemmaraju N. Rao (San Antonio, Texas); James W. Cessac (Floresville, Texas); Carmie K. Acosta (San Antonio, Texas) |
ABSTRACT | A compound having the general formula: in which: R1 is a member selected from the group consisting of —OCH3, —SCH3, —N(CH3)2, —NHCH3, —CHO, —COCH3 and —CHOHCH3; R2 is a member selected from the group consisting of halogen, alkyl, acyl, hydroxy, alkoxy, acyloxy, alkyl carbonate, cypionyloxy, S-alkyl and S-acyl; R3 is a member selected from the group consisting of alkyl, hydroxy, alkoxy and acyloxy; R4 is a member selected from the group consisting of hydrogen and alkyl; and X is a member selected from the group consisting of ═O and ═N—OR5, wherein R5 is a member selected from the group consisting of hydrogen and alkyl. In addition to providing the compounds of Formula I, the present invention provides methods wherein the compounds of Formula I are advantageously used, inter alia, to antagonize endogenous progesterone; to induce menses; to treat endometriosis; to treat dysmenorrhea; to treat endocrine hormone-dependent tumors; to treat uterine fibroids; to inhibit uterine endometrial proliferation; to induce labor; and for contraception. |
FILED | Thursday, December 17, 2009 |
APPL NO | 12/641172 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/182 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003633 | Robertson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Gavin P. Robertson (Hummelstown, Pennsylvania); SubbRao V. Madhunapantula (Hershey, Pennsylvania); Shantu Amin (Union City, New Jersey); Dhimant Desai (Mechanicsburg, Pennsylvania) |
ABSTRACT | Anti-cancer compositions and methods are described including one or more compounds having the structural formula I: where R is phenyl, where R1 is (CH2)n—Se—C(═NH)—NH2, where R2 is (CH2)n—Se—C(═NH)—NH2 or R2 is H, and where each n is independently 2, 3, 4, 5, 6, 7, or 8. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including one or more compounds having the structural formula I to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including one or more compounds having the structural formula I to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. Compositions of the present invention inhibit Akt enzymes, iNOS, and increase MAP kinase activity such that cancer cells contacted with the compositions are inhibited. |
FILED | Tuesday, April 14, 2009 |
APPL NO | 12/423366 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003674 | Barklis |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Eric Barklis (Lake Oswego, Oregon) |
ABSTRACT | Disclosed herein are compounds, compositions and methods for treating or ameliorating flavivirus infections. This is particularly important because the present disclosure provides methods for treating flavivirus infections for which there is no effective vaccine. |
FILED | Thursday, March 15, 2007 |
APPL NO | 12/279831 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/360 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003687 | Dong et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Kosan Biosciences Incorporated (Princeton, New Jersey) |
INVENTOR(S) | Steven D. Dong (San Francisco, California); Daniel V. Santi (San Francisco, California) |
ABSTRACT | Esters of compounds in the leptomycin family, having a structure according to formula I where R, R10, R11, R12, R13, and R14 are as defined herein, exhibit anti-tumor properties. |
FILED | Monday, September 11, 2006 |
APPL NO | 11/991879 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/451 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003692 | Schein et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Mission Pharmacal Co. (San Antonio, Texas) |
INVENTOR(S) | Catherine H. Schein (Friendswood, Texas); Johnny W. Peterson (Dickinson, Texas); Scott R. Gilbertson (Galveston, Texas); Deliang Chen (League City, Texas); Maria Estrella-Jimenez (Lawrenceville, New Jersey); Mary A. Walter (Fair Oaks Ranch, Texas); Jian Gao (Helotes, Texas) |
ABSTRACT | Fluorene-based molecules and their derivatives are described in compositions for the treatment of intestinal fluid loss. |
FILED | Friday, June 13, 2008 |
APPL NO | 12/139212 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/468 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003693 | Piomelli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Universita Degli Studi di Urbino (Urbino, Italy); Universita Degl Studi di Parma (Parma, Italy) |
INVENTOR(S) | Daniele Piomelli (Irvine, California); Andrea Duranti (Urbino, Italy); Andrea Tontini (Pesaro, Italy); Marco Mor (Ghedi, Italy); Giorgio Tarzia (Petriano, Italy) |
ABSTRACT | Fatty acid amide hydrolase inhibitors of the Formula: are provided wherein X is NH, CH2, O, or S; Q is O or S; Z is O or N; R is an aromatic moiety selected from the group consisting of substituted or unsubstituted aryl; substituted or unsubstituted biphenylyl, substituted or unsubstituted naphthyl, and substituted or unsubstituted phenyl; substituted or unsubstituted terphenylyl; substituted or unsubstituted cycloalkyl, heteroaryl, or alkyl; and R1 and R2 are independently selected from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, and substituted or unsubstituted phenyl, substituted or unsubstituted biphenylyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl; with the proviso that if Z is O, one of R1 and R2 is absent, and that if Z is N, optionally R1 and R2 may optionally be taken together to form a substituted or unsubstituted N-heterocycle or substituted or unsubstituted heteroaryl with the N atom to which they are each attached. Pharmaceutical compositions comprising the compounds of Formula I and methods of using them to inhibit FAAH and/or treat appetite disorders, glaucoma, pain, insomnia, and neurological and psychological disorders including anxiety disorders, epilepsy, and depression are provided. |
FILED | Friday, July 28, 2006 |
APPL NO | 11/496051 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/481 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003764 | Schmidt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Laura S. Schmidt (Mt. Airy, Maryland); Michelle Warren (New Market, Maryland); Jorge R. Toro (Washington, District of Columbia); Berton Zbar (Garrett Park, Maryland); Michael L. Nickerson (Shepherdston, West Virginia); W. Marston Linehan (North Bethesda, Maryland); Maria L. Turner (Washington, District of Columbia) |
ABSTRACT | The present disclosure relates to Birt-Hogg-Dubé syndrome, nucleic acids encoding the BHD gene, and antibodies that specifically bind to the BHD protein (folliculin). In addition, the present disclosure relates to methods of diagnosing BHD disease and related conditions, such as spontaneous pneumothorax and kidney cancer, by detection of altered expression of folliculin using folliculin-specific antibodies. |
FILED | Friday, December 12, 2008 |
APPL NO | 12/334361 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003801 | Nicolaou et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (LaJolla, California) |
INVENTOR(S) | Kyriacos C. Nicolaou (La Jolla, California); Benjamin Pratt (San Diego, California); Stellios Arseniyadis (Paris, France) |
ABSTRACT | A highly active synthetic epothilone compound whose activity exceeds that of either epothilone EpoA or EpoB when assayed as a cytotoxic agent against a cancer cell line is disclosed as is a pharmaceutical composition containing the synthetic epothilone. |
FILED | Thursday, November 09, 2006 |
APPL NO | 12/092038 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 548/146 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003852 | Gaxiola et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Roberto A. Gaxiola (Tempe, Arizona); Gerald R. Fink (Chestnut Hill, Massachusetts); Seth L. Alper (Boston, Massachusetts) |
ABSTRACT | Transgenic plants are described which are engineered to overexpress vacuolar H+-PPase. Plants such as tobacco and petunia transformed with A. Thaliana AVP-1 are shown to have increased meristematic activity resulting in larger leaves, stem, flower, fruit, root structures, increased salt tolerance, enhanced drought and freeze tolerance. Methods of making such plants are also described. |
FILED | Tuesday, March 31, 2009 |
APPL NO | 12/384115 |
ART UNIT | 1638 — Organic Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/295 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003948 | Haselman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Michael Haselman (Renton, Washington); Robert S. Miyaoka (Shoreline, Washington); Thomas K. Lewellen (Port Ludlow, Washington); Scott Hauck (Seattle, Washington) |
ABSTRACT | A method for estimating the start time of an electronic pulse generated in response to a detected event, for example the start time for pulses received in response to photon detection in positron emission tomography, includes providing a detector that detects an external event and generates an electronic analog pulse signal. A parameterized ideal curve shape is selected to represent analog pulse signals generated by the detector. Upon receiving an analog pulse signal, it may be filtered, and then digitized, and normalized based on the area of the digital signal. Using at least one point of the normalized digital pulse signal, a curve from the parameterized ideal curve shape is selected, that best represents the received analog pulse signal, and the selected curve is used to estimate the pulse start time. |
FILED | Monday, November 03, 2008 |
APPL NO | 12/264093 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/362 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004281 | Bottomley et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Paul A. Bottomley (Columbia, Maryland); Ananda Kumar (Baltimore, Maryland) |
ABSTRACT | Featured is a device for NMR or MRI signals from excited nuclei as well as related apparatus, systems and methods. The device includes a strip array antenna including one or more conductor and N reactive tuning components, where N is an integer ≧1 at least one of the N reactive components is electrically coupled to each of the one or more conductors as well as to ground/virtual ground. The apparent electrical length of the conductors is tuned with the reactive tuning components so it is equal to be about nλ/4, where n is an integer ≧1 and λ is the wavelength of the signal to be detected. The length of the strip also is such as to be substantially in the approximate range of 1.3 times the depth of interest. The strip conductors are also combined with loop coils to form quadrature detectors. |
FILED | Friday, September 10, 2010 |
APPL NO | 12/879430 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/318 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005184 | Chen |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Guang-Hong Chen (Madison, Wisconsin) |
ABSTRACT | A line scan cone beam CT imaging system irradiates an object with an x-ray cone beam for multiple views. A projection data set of the object is acquired at each view. Between views, the cone beam and detector array are translated along parallel lines in opposite directions. An image is generated by converting the cone beam projection data set of the real object into a parallel-beam projection data set corresponding to a virtual object and using a total variation minimization image reconstruction algorithm to reconstruct a virtual image of the virtual object. The reconstruction algorithm includes the constraint that the Fourier transform of the reconstructed virtual image matches the known Fourier coefficients in the set of converted parallel-beam projections of the virtual object. The reconstructed virtual image is then transformed into an image of the real object. |
FILED | Tuesday, April 24, 2007 |
APPL NO | 11/739458 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005314 | Ortyn et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Amnis Corporation (Seattle, Washington) |
INVENTOR(S) | William Ortyn (Bainbridge Island, Washington); David Basiji (Seattle, Washington); Keith Frost (Seattle, Washington); Luchuan Liang (Woodinville, Washington); Richard Bauer (Kirkland, Washington); Brian Hall (Seattle, Washington); David Perry (Woodinville, Washington) |
ABSTRACT | A high speed, high-resolution flow imaging system is modified to achieve extended depth of field imaging. An optical distortion element is introduced into the flow imaging system. Light from an object, such as a cell, is distorted by the distortion element, such that a point spread function (PSF) of the imaging system is invariant across an extended depth of field. The distorted light is spectrally dispersed, and the dispersed light is used to simultaneously generate a plurality of images. The images are detected, and image processing is used to enhance the detected images by compensating for the distortion, to achieve extended depth of field images of the object. The post image processing preferably involves de-convolution, and requires knowledge of the PSF of the imaging system, as modified by the optical distortion element. |
FILED | Monday, December 11, 2006 |
APPL NO | 11/609269 |
ART UNIT | 2447 — Computer Networks |
CURRENT CPC | Image analysis 382/275 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005526 | Martin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | David C. Martin (Ann Arbor, Michigan); Sarah Richardson-Burns (Ypsilanti, Michigan); Donghwan Kim (Ann Arbor, Michigan); Jeffrey L. Hendricks (Ann Arbor, Michigan); Laura Povlich (Taylor, Michigan); Mohamad Reza Abidian (Ann Arbor, Michigan); Matthew Meier (Ann Arbor, Michigan) |
ABSTRACT | Bioelectrodes having enhanced biocompatible and biomimetic features are provided. Methods of making and using the bioelectrodes are further provided. A biologically integrated bioelectrode device and method for detecting electronic signals using a bioelectrode comprising a first electrically conductive substrate and a biological component. The bioelectrode also comprises a conductive polymer electrically coupling the first electrically conductive substrate and the biological component to define a bioelectrode. The bioelectrode can transmit or receive an electrical signal between the electrically conductive substrate and the biological component and conductive polymer. |
FILED | Wednesday, August 30, 2006 |
APPL NO | 11/512479 |
ART UNIT | 3739 — Optics |
CURRENT CPC | Surgery 6/372 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005527 | Zelenchuk |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Luma Imaging Corporation (San Diego, California) |
INVENTOR(S) | Alex R. Zelenchuk (Stoughton, Massachusetts) |
ABSTRACT | A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, one of which corresponds to an isosbestic point. In one example, the isosbestic point occurs at about 431 nm. The intensities of the observed signals are normalized using the 431 nm intensity. A score is determined using the ratios in a discriminant analysis. The tissue under examination is resected or not, based on the diagnosis of disease or health, according to the outcome of the discriminant analysis. |
FILED | Wednesday, December 12, 2007 |
APPL NO | 11/955165 |
ART UNIT | 3737 — Optics |
CURRENT CPC | Surgery 6/407 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005627 | Porwancher |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Richard Porwancher (Princeton, New Jersey) |
ABSTRACT | A multivariate diagnostic method based on optimizing diagnostic likelihood ratios through the effective use of multiple diagnostic tests is disclosed. The Neyman-Pearson Lemma provides a mathematical basis to produce optimal diagnostic results. The method can comprise identifying those tests optimal for inclusion in a diagnostic panel, weighting the result of each component test based on a multivariate algorithm described below, adjusting the algorithm's performance to satisfy predetermined specificity criteria, generating a likelihood ratio for a given patient's test results through said algorithm, providing a clinical algorithm that estimates the pretest probability of disease based on individual clinical signs and symptoms, combining the likelihood ratio and pretest probability of disease through Bayes' Theorem to generate a posttest probability of disease, interpreting that result as either positive or negative for disease based on a cutoff value, and treating a patient for disease if the posttest probability exceeds the cutoff value. |
FILED | Saturday, September 08, 2007 |
APPL NO | 11/852283 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/20 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 08001901 | Bass |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jamie Bass (Elnora, Indiana) |
ABSTRACT | A system and method of detecting, processing, and selectively responding to radio frequency transmissions detected by at least one projectile deployed above a geographic area. |
FILED | Tuesday, January 11, 2011 |
APPL NO | 13/004356 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition and explosives 12/382 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08001902 | Bass |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jamie Bass (Elnora, Indiana) |
ABSTRACT | A system and method of detecting, processing, and selectively responding to radio frequency transmissions detected by at least one projectile deployed above a geographic area. |
FILED | Thursday, October 09, 2008 |
APPL NO | 12/248383 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition and explosives 12/387 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002142 | Losinski et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Armand Losinski (Albuquerque, New Mexico); Matthew Tehan (Albuquerque, New Mexico) |
ABSTRACT | An apparatus is provided for a fuel tank system for an air vehicle. The system comprises a container having an interior adapted to hold fuel, the container comprising a first opening placing the interior in fluid communication with the ambient atmosphere, and a volumetrically-adjustable sizing device adapted to change volume in response to changes in surrounding air pressure, the sizing element disposed within the container and adapted to contain a fluid. |
FILED | Thursday, June 19, 2008 |
APPL NO | 12/142586 |
ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Receptacles 220/721 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002205 | Lambert et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Delphi Technologies Holding S.arl (, None) |
INVENTOR(S) | Malcolm Lambert (Gillingham, United Kingdom); Andrew Limmer (Sudbury, United Kingdom); Mark Norman (Sudbury, United Kingdom); Michael Mcloone (Sudbury, United Kingdom) |
ABSTRACT | An injection nozzle for an internal combustion engine has a valve member (10) with a seating line (112) defining a seat diameter, the seating line (112) being engageable with a seating surface (14) to control fuel injection by the nozzle, in use. The seating line is defined by an annular ridge (40, 44, 46), integrally formed with the valve needle (10), so as to reduce variations in the seat diameter which would otherwise arise at manufacture due to contact between the valve needle (10) and the seating surface (14) in regions other than at the seating line. The invention provides an advantage in manufacture as repeatability and consistency of the geometry, and in particular the effective seat diameter, of nozzle products is improved. |
FILED | Wednesday, October 06, 2004 |
APPL NO | 10/575052 |
ART UNIT | 3752 — Fluid Handling and Dispensing |
CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/533.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002235 | Vyawahare et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Saurabh Vyawahare (Pasadena, California); Suresh Situala (Pasadena, California); Dvin Adalian (Alexandria, Virginia); Axel Scherer (Laguna Beach, California) |
ABSTRACT | Microfluidic valves constructed from elastomeric materials as the valve body components and employing shape memory alloy in wire form as the valve actuator. Various configurations of individual valves having both normally open and normally closed states are described. Apparatus using such valves and providing logic functionality with fluidic logic outputs are discussed. Apparatus that can be used for materials processing at the nano- or micro-scale are presented. Various forms of logical control of valve arrays are explained. |
FILED | Tuesday, September 11, 2007 |
APPL NO | 11/853531 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Valves and valve actuation 251/11 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002599 | Grabe et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Zachary A. Grabe (West Palm Beach, Florida); Jason B. Crawford (Wellington, Florida) |
ABSTRACT | Systems and methods for underwater descent rate reduction are provided. In one embodiment, a method for underwater descent rate reduction for an underwater delivery vehicle is provided. The method comprises: opening a first valve based on a first hydrostatic pressure to permit water to flow into a first chamber of a hydrostatic pressure driven piston assembly; developing a pressure differential across a piston head separating the first chamber from a second chamber of the hydrostatic pressure driven piston assembly; pushing the piston head into the second chamber to extend a piston rod from the hydrostatic pressure driven piston assembly; and pivoting a deflecting flap downward into a direction of vehicle descent as the piston rod extends. |
FILED | Wednesday, August 19, 2009 |
APPL NO | 12/544015 |
ART UNIT | 3617 — Fluid Handling and Dispensing |
CURRENT CPC | Buoys, rafts, and aquatic devices 441/10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002914 | D'Arche et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Steven P. D'Arche (Odon, Indiana); Travis Swanson (Bloomfield, Indiana) |
ABSTRACT | A flash powder formulation for use in flash grenades that produces reduced smoke containing from about 10 percent by weight to about 60 percent by weight of zirconium hydride, from about 40 percent by weight to about 90 percent by weight CAN, and from zero percent by weight to about 5 percent by weight of a binder material. |
FILED | Tuesday, March 24, 2009 |
APPL NO | 12/409956 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosive and thermic compositions or charges 149/37 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002917 | Boddu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Veera M. Boddu (Champaign, Illinois); Reddy Damavarapu (Hackettstown, New Jersey); Krishnaiah Abburi (Tirupati, India) |
ABSTRACT | A method of adjusting the yield of a manufactured compound comprising primarily two energetic materials to yield a product comprising primarily one of the two energetic materials. Specifically, embodiments of the present invention provide a method of purifying a compound primarily comprising RDX and HMX to achieve a desired purity of RDX with an acceptable yield percentage. By adding sufficient acetonitrile (ACN) to the manufactured compound to dissolve it and form a solution; adding a pre-specified volume of water to the resultant solution and stirring sufficiently to precipitate at least the RDX; separating and drying the precipitate, a pre-specified purity and yield percentage of RDX may be obtained by varying the volume of water added. The process uses relatively environmentally benign recyclable solvents at ambient temperature and pressure reducing both environmental impact and energy costs. |
FILED | Monday, February 09, 2009 |
APPL NO | 12/367562 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosive and thermic compositions or charges 149/92 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002956 | O'Connor et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Timothy J O'Connor (Troy, New York); Frederick J Nelson (Schenectady, New York) |
ABSTRACT | A stand-off for maintaining the separation between an electrode and an object during a flow-through electroplating process is disclosed. The stand-off comprises a substantially streamlined shape that mitigates the effects of shadowing during deposition. |
FILED | Thursday, February 28, 2008 |
APPL NO | 12/038941 |
ART UNIT | 1759 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Chemistry: Electrical and wave energy 24/279 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002958 | Zhou et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Xintek, Inc. (Research Triangle Park, North Carolina) |
INVENTOR(S) | Otto Z. Zhou (Chapel Hill, North Carolina); Bo Gao (Carrboro, North Carolina); Guozhen Yue (Carrboro, North Carolina); Soojin Oh (Carrboro, North Carolina) |
ABSTRACT | A method for depositing a coating of a nanostructure material onto a substrate includes: (1) forming a solution or suspension of containing the nanostructure material; (2) selectively adding “chargers” to the solution; (3) immersing electrodes in the solution, the substrate upon which the nanostructure material is to be deposited acting as one of the electrodes; (4) applying a direct and/or alternating current electrical field between the two electrodes for a certain period of time thereby causing the nanostructure materials in the solution to migrate toward and attach themselves to the substrate electrode; and (5) subsequent optional processing of the coated substrate. |
FILED | Friday, November 04, 2005 |
APPL NO | 11/266318 |
ART UNIT | 1759 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Chemistry: Electrical and wave energy 24/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002963 | Andelman et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Biosource, Incorporated (London, United Kingdom) |
INVENTOR(S) | Marc D. Andelman (Worcester, Massachusetts); Gregory S. Walker (Grafton, Massachusetts) |
ABSTRACT | Flow-through capacitors are provided with one or more charge barrier layers. Ions trapped in the pore volume of flow-through capacitors cause inefficiencies as these ions are expelled during the charge cycle into the purification path. A charge barrier layer holds these pore volume ions to one side of a desired flow stream, thereby increasing the efficiency with which the flow-through capacitor purifies or concentrates ions. |
FILED | Friday, August 01, 2008 |
APPL NO | 12/221375 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/687 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003078 | Lanza et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Barnes-Jewish Hospital (St. Louis, Missouri) |
INVENTOR(S) | Gregory M. Lanza (St. Louis, Missouri); Samuel A. Wickline (St. Louis, Missouri); Garry E. Kiefer (Richardson, Texas); Phillip S. Athey (Lake Jackson, Texas) |
ABSTRACT | MRI contrast agents that employ paramagnetic agents and chemical exchange saturation transfer (paraCEST) and which are coupled to targeted particulate delivery vehicles provide sufficient concentration of the paraCEST contrast agents to obtain useful images of target tissues or organs. In addition, the image contrast may be switched on or off with a presaturation radio frequency pulse, avoiding the necessity obtaining pre-injection and post-injection images. |
FILED | Thursday, March 29, 2007 |
APPL NO | 11/693647 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.365 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003374 | Heeger et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alan J. Heeger (Santa Barbara, California); Chunhai Fan (Shanghai, China PRC); Kevin Plaxco (Santa Barbara, California) |
ABSTRACT | A reagentless, reusable bioelectronic DNA, or other oligonucleotide sequence sensor is disclosed. The sensor includes an oligonucleotide (aptamer) probe tagged with a electroactive, redoxable moiety, self-assembled on or near an electrode. This surface-confined oligonucleotide (aptamer) probe structure undergoes hybridization-induced conformational change in the presence of the target which changes the electron-transfer distance between the redoxable moiety and the electrode thereby providing a detectable signal change. In an alternative embodiment, the target can harbor the redoxable moiety. |
FILED | Friday, July 29, 2005 |
APPL NO | 11/193318 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003378 | Wikswo et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Franz J. Baudenbacher (Franklin, Tennessee); Ales Prokop (Nashville, Tennessee); Eugene LeBoeuf (Franklin, Tennessee); Chang Y. Chung (Franklin, Tennessee); David E. Cliffel (Nashville, Tennessee); Frederick R. Haselton (Nashville, Tennessee); William H. Hofmeister (Nashville, Tennessee); Charles P. Lin (Brentwood, Tennessee); Lisa J. McCawley (Nashville, Tennessee); Randall S. Reiserer (Nashville, Tennessee); Mark A. Stremler (Franklin, Tennessee) |
ABSTRACT | A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel. |
FILED | Thursday, March 05, 2009 |
APPL NO | 12/398825 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/289.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003385 | Sukumar et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Sanofi Pasteur Vax Design Corp. (Orlando, Florida) |
INVENTOR(S) | Selva Sukumar (Berkeley, California); Mohey Eldin M. El Shikh (Richmond, Virginia); John G. Tew (Mechanicsville, Virginia); Guzman Sanchez-Schmitz (Orlando, Florida); Donald Drake, III (Orlando, Florida); Luis Mosquera (Oviedo, Florida); Conan Li (Los Altos, California); Anatoly M. Kachurin (Orlando, Florida); Russell Higbee (Orlando, Florida); Heather Fahlenkamp (Cleveland, Oklahoma); Eric Mishkin (Winter Springs, Florida); William L. Warren (Orlando, Florida) |
ABSTRACT | The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. |
FILED | Wednesday, February 17, 2010 |
APPL NO | 12/707563 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/326 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003387 | Sukumar et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Sanofi Pasteur Vaxdesign Corp. (Orlando, Florida) |
INVENTOR(S) | Selva Sukumar (Berkeley, California); Mohey Eldin M. El Shikh (Richmond, Virginia); John G. Tew (Mechanicsville, Virginia); Guzman Sanchez-Schmitz (Orlando, Florida); Donald Drake, III (Orlando, Florida); Luis Mosquera (Oviedo, Florida); Eric Mishkin (Winter Springs, Florida); Anatoly M. Kachurin (Orlando, Florida); Russell Higbee (Orlando, Florida); Conan Li (Los Altos, California); William L. Warren (Orlando, Florida); Heather Fahlenkamp (Cleveland, Oklahoma) |
ABSTRACT | The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. |
FILED | Thursday, December 21, 2006 |
APPL NO | 11/642938 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003403 | Levitsky |
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APPLICANT(S) | |
ASSIGNEE(S) | Emitech, Inc (Fall River, Massachusetts) |
INVENTOR(S) | Igor A. Levitsky (Fall River, Massachusetts) |
ABSTRACT | A chemical sensor for detecting organic or inorganic target vapors and comprising a silicon member having a silicon surface with semiconductor pores therein, at least one luminescent sensory material entrapped in the semiconductor pores. The luminescent spectral material is exposed to the target vapors, wherein an excitation of the at least one luminescent sensory material results in a luminescent spectral response due to emission interference. The change in the luminescent spectral response is measured during this exposure. |
FILED | Wednesday, March 19, 2008 |
APPL NO | 12/051233 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003504 | Immorlica et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire); Biogen IDEC MA Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Anthony A. Immorlica (Mont Vernon, New Hampshire); Pane-chane Chao (Nashua, New Hampshire); Kanin Chu (Nashua, New Hampshire) |
ABSTRACT | A method for fabrication of a field effect transistor gate, with or without field plates, includes the steps of defining a relatively thin Schottky metal layer by a lithography/metal liftoff or metal deposition/etch process on a semiconductor surface. This is followed by depositing a dielectric passivation layer over the entire wafer and defining a second lithographic pattern coincident with or slightly inset from the boundaries of the previously defined metal gate layer. This is followed by etching the dielectric using dry or wet etching techniques and stripping the resist, followed by exposing and developing a third resist pattern to define the thicker gate metal layers required for electrical conductivity and also for the field plate if one is utilized. The final step is depositing gate and/or field plate metal, resulting in a gate electrode and an integral field plate. |
FILED | Friday, August 31, 2007 |
APPL NO | 12/086854 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/582 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003713 | Carlo et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Steven Carlo (Bowie, Maryland); Arthur W Snow (Alexandria, Virginia); Richard S. Pong (Colesville, Maryland); James S Shirk (Alexandria, Virginia); Steven R Flom (Temple Hills, Maryland) |
ABSTRACT | High concentrations of dye may be prepared in combination with thermoplastic polymers and used in optical polymers as monomeric and dimeric molecular solutions. The method of preparing high concentration levels allows the control over the aggregation of dye molecules that is required to maintain effective nonlinear operation. The present invention is applicable to many systems and is essential to the successful production of working optical limiting devices and other optically transparent polymeric devices, as well as other photonic applications, such as nonlinear optics. |
FILED | Tuesday, December 08, 2009 |
APPL NO | 12/633004 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 523/135 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003965 | Grbic et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Anthony Grbic (Ann Arbor, Michigan); Roberto D. Merlin (Ann Arbor, Michigan) |
ABSTRACT | Planar sub-wavelength structures provide superlensing, i.e., electromagnetic focusing beyond the diffraction limit. The planar structures use diffraction to force the input field to converge to a spot on the focal plane. The sub-wavelength patterned structures manipulate the output wave in such a manner as to form a sub-wavelength focus in the near field. In some examples, the sub-wavelength structures may be linear grating-like structures that can focus electromagnetic radiation to lines of arbitrarily small sub-wavelength dimension, or two dimensional grating-like structures and Bessel (azimuthally symmetric) structures that can focus to spots of arbitrarily small sub-wavelength dimensions. The particular pattern for the sub-wavelength structures may be derived from the desired focus. Some examples describe sub-wavelength structures that have been implemented to focus microwave radiation to sub-wavelength dimensions in the near field. |
FILED | Monday, May 19, 2008 |
APPL NO | 12/123434 |
ART UNIT | 2821 — Optics |
CURRENT CPC | Radiant energy 250/505.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003979 | Cho et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
INVENTOR(S) | Namchul Cho (Daejeon, South Korea); Kaushik Roy Choudhury (Gainesville, Florida); Yudhisthira Sahoo (Amherst, New York); Kwang Sup Lee (Daejeon, South Korea); Paras N. Prasad (Williamsville, New York) |
ABSTRACT | The present invention relates to a method of preparing a carbon nanotube-quantum dot conjugate having a high density of quantum dots (QDs) on its surface. This method involves providing a plurality of semiconductor quantum dots and providing a thiol-functionalized carbon nanotube having a plurality of terminal thiol groups on its surface. The plurality of semiconductor quantum dots are attached to the surface of the carbon nanotube under conditions effective to yield a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention also relates to a carbon nanotube-quantum dot conjugate having a high density of quantum dots on its surface. The present invention further relates to a photodetector device. This device includes a substrate and a nanocomposite layer. The nanocomposite layer includes a plurality of the carbon nanotube-quantum dot conjugates previously described. |
FILED | Monday, February 12, 2007 |
APPL NO | 11/673850 |
ART UNIT | 2891 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/40 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004017 | Eden et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | J. Gary Eden (Mahomet, Illinois); Sung-Jin Park (Champaign, Illinois); Kwang-Soo Kim (Champaign, Illinois) |
ABSTRACT | A preferred embodiment microcavity plasma device array of the invention includes a plurality of first metal circumferential metal electrodes that surround microcavities in the device. The first circumferential electrodes are buried in a metal oxide layer and surround the microcavities in a plane transverse to the microcavity axis, while being protected from plasma in the microcavities by the metal oxide. In embodiments of the invention, the circumferential electrodes can be connected in patterns. A second electrode(s) is arranged so as to be isolated from said first electrodes by said first metal oxide layer. In some embodiments, the second electrode(s) is in a second layer, and in other embodiments the second electrode(s) is also within the first metal oxide layer. A containing layer, e.g., a thin layer of glass, quartz, or plastic, seals the discharge medium (plasma) into the microcavities. In a preferred method of formation embodiment, a metal foil or film is obtained or formed with micro-holes. The foil is anodized to form metal oxide. One or more self-patterned metal electrodes are automatically formed and buried in the metal oxide created by the anodization process. The electrodes form in a closed circumference around each microcavity in a plane(s) transverse to the microcavity axis, and can be electrically isolated or connected. Preferred embodiments provide inexpensive microplasma device electrode structures and a fabrication method for realizing microplasma arrays that are lightweight and scalable to large areas. Electrodes buried in metal oxide and complex patterns of electrodes can also be formed without reference to microplasma devices—that is, for general electrical circuitry. |
FILED | Tuesday, July 24, 2007 |
APPL NO | 11/880698 |
ART UNIT | 2822 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/211 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004127 | Potter |
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APPLICANT(S) | |
ASSIGNEE(S) | Foster-Miller, Inc. (Waltham, Massachusetts) |
INVENTOR(S) | Steven D. Potter (Bedford, Massachusetts) |
ABSTRACT | A rotary reluctance motor includes a set of inner disks each having an inner diameter root, an outer diameter free end, and a plurality of alternating high permeability teeth and low permeability material segments. A set of outer disks is interleaved with the inner disks to form a disk stack. Each outer disk has an outer diameter root, an inner diameter free end, and a plurality of alternating high permeability teeth and low permeability material segments. The inner and outer disks are configured to bear against and support each other in response to axial magnetic forces. Flux return portions are disposed axially adjacent the disks at each end of the disk stack. A coil is associated with the roots of one of the sets of disks and configured to provide axial flux through the disk stack to rotate one set of disks with respect to the other set of disks. |
FILED | Thursday, April 24, 2008 |
APPL NO | 12/150003 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/49.440 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004156 | Symko et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Orest G. Symko (Salt Lake City, Utah); Young S. Kwon (Salt Lake City, Utah) |
ABSTRACT | A thermoacoustic array energy converter consists of heat driven thermoacoustic prime movers in parallel coupled by means of an acoustic cavity to a piezoelectric electrical generator whose output is rectified and fed to an energy storage element. The prime movers convert heat to sound in a resonator. The sound form a phase-locked array is converted to electricity by means of the piezoelectric element. The generated electric energy is converted to DC by means of a rectifier set and it is then stored in a battery or supercapacitor. The generated electric energy can also be converted to power line frequency. |
FILED | Wednesday, January 23, 2008 |
APPL NO | 12/018762 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/339 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004216 | Kayser |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | David J. Kayser (Saint Inigoes, Maryland) |
ABSTRACT | A variable intensity LED illumination system is configured to provide a change in luminance versus input voltage that corresponds to a desired transfer function, such as the dimming characteristics of an incandescent lamp, which more closely resembles the response of the human eye. The system also advantageously provides overvoltage protection, increased brightness, energy efficiency, and significantly better longevity and ruggedness, compared to incandescent lamps. |
FILED | Friday, May 02, 2008 |
APPL NO | 12/114063 |
ART UNIT | 2821 — Electrical Circuits and Systems |
CURRENT CPC | Electric lamp and discharge devices: Systems 315/312 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004278 | Worledge et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York); Infineon Technologies North America Corp. (San Jose, California) |
INVENTOR(S) | Daniel Christopher Worledge (Poughquag, New York); Philip Louis Trouilloud (Norwood, New Jersey); David William Abraham (Croton-on-Hudson, New York); Joerg Dietrich Schmid (Hopewell Junction, New York) |
ABSTRACT | Probes are electrically connected to a surface of a tunnel junction film stack comprising a free layer, a tunnel barrier, and a pinned layer. Resistances are determined for a variety of probe spacings and for a number of magnetizations of one of the layers of the stack. The probe spacings are a distance from a length scale, which is related to the Resistance-Area (RA) product of the tunnel junction film stack. Spacings from as small as possible to about 40 times the length scale are used. Beneficially, the smallest spacing between probes used during a resistance measurement is under 100 microns. A measured in-plane MagnetoResistance (MR) curve is determined from the “high” and “low” resistances that occur at the two magnetizations of this layer. The RA product, resistances per square of the free and pinned layers, and perpendicular MR are determined through curve fitting. |
FILED | Tuesday, August 11, 2009 |
APPL NO | 12/539080 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/223 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004455 | Wright et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Buford S. Wright (Bedford, Indiana); Joseph Dang (Bloomington, Indiana) |
ABSTRACT | A method and apparatus for simulating antenna apparatuses are provided. In an illustrative embodiment, the apparatus comprises a first portion configured to produce a first and third plurality of signals and to receive a second plurality of signals from a transmitter, wherein said first and third plurality of signals are determined by more than one of a plurality of relationships between said transmitter and at least one antenna apparatus adapted to receive signals from said transmitter. |
FILED | Saturday, February 09, 2008 |
APPL NO | 12/028798 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/169 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004660 | Brown |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washingotn, District of Columbia) |
INVENTOR(S) | Jerry G. Brown (Bloomington, Indiana) |
ABSTRACT | A simulation system for predicting a likelihood of whether a target object positioned in an environment will be detected by a detection system when illuminated by a laser source. The simulation system may be used for a laser rangefinder application and a laser designator application. The simulation system may provide a detection probability of the target object at a specified range to the detection system or a plurality of detection probabilities as a function of the range to the detection system. The simulation system may provide an indication of an overlap of the beam provided by the laser source on the target object. The simulation system may determine the effect of vibration on the detection of the target object at a specified range. |
FILED | Tuesday, March 31, 2009 |
APPL NO | 12/414773 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Optics: Measuring and testing 356/5.20 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004676 | Prasad et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
INVENTOR(S) | Paras N. Prasad (Williamsville, New York); Przemyslaw P. Markowicz (Woodbury, Minnesota); Wing Cheung Law (Amherst, New York); Andrei Kabashin (St.-Leonard, Canada); Sergiy Patskovsky (Montreal, Canada) |
ABSTRACT | A method is provided for detection of analytes using the Surface Plasmon Resonance effect. The method comprises providing a metal film on a transparent substrate. The free surface of the metal film is exposed to a test sample. An anlyte in the sample can interact directly with the metal film or via analyte binding molecules (ABMs) complexed to the film. Light is directed incident to the surface of film in contact with the substrate. Light is reflected from the surface of the film under SPR conditions. The reflected light is collected and the second and/or third harmonics of the resulting electrical signal, which are indicative of the phase and polarization state of the reflected light, are determined. The second and third harmonics are correlated to the presence and/or concentration of the analyte. |
FILED | Monday, February 11, 2008 |
APPL NO | 12/069700 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/369 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004762 | Cathey, Jr. et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents Of The University Of Colorado, a body corporate (Denver, Colorado) |
INVENTOR(S) | Wade Thomas Cathey, Jr. (Boulder, Colorado); Edward Raymond Dowski, Jr. (Lafayette, Colorado) |
ABSTRACT | Systems and methods for generating an optical image include forming an optical image with at least one optical element of an optical imager while modifying wavefront phase. Modifying the phase does not reduce an optical bandpass limited by an aperture of the optical imager. The systems and methods also include detecting the optical image over a range of spatial frequencies such that there are no zeros in an optical transfer function of the optical imager over detected spatial frequencies within the optical bandpass and over an extended depth of focus that is larger than a depth of focus occurring without modifying wavefront phase. |
FILED | Monday, October 13, 2008 |
APPL NO | 12/250343 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/558 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004841 | Cipolla et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Thomas M. Cipolla (Katonah, New York); Shurong Tian (Mount Kisco, New York); Evan George Colgan (Chestnut Ridge, New York); Paul W. Coteus (Yorktown Heights, New York); Shawn Anthony Hall (Pleasantville, New York) |
ABSTRACT | A cooling or heat transfer apparatus and method is disclosed for cooling an electronic device. The apparatus includes a heat producing electronic device which may include an electronic circuit card with many heat sources. A heat transfer device is connected to the heat producing electronic device which is thermally communicating with the heat producing device for transferring heat from the heat producing device to the heat transfer device. A heat conduit is connected to the heat transfer device and thermally communicating with the heat transfer device for transferring heat to the heat conduit from the heat transfer device. A cooling housing is connected to the heat conduit and the cooling housing thermally communicating with the heat conduit for transferring heat to the cooling housing from the heat conduit. The apparatus enables the replacement of circuit cards in the field because it eliminates the need to apply thermal-interface materials. |
FILED | Tuesday, May 06, 2008 |
APPL NO | 12/115618 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/699 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005002 | Gandham et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Shashidhar R. Gandham (Richardson, Texas); Ying Zhang (Cupertino, California); Qingfeng Huang (San Jose, California) |
ABSTRACT | One embodiment of the present invention provides a system that performs a query-based convergecast scheduling in a convergecast network, which includes a base-station and a plurality of nodes. During operation, the system receives a convergecast tree for the convergecast network. Each node in the convergecast tree is associated with a hop-count to the base-station through a specific branch and each node can generate zero or more packets to transmit. Next, the system initializes a query from the base-station, wherein the query is successively propagated to the nodes through the branches. In response to the query, the system computes distributed-timing-information indicating a packet transmission schedule for the nodes. The system next aggregates the distributed-timing-information associated with the nodes toward the base-station through the branches. The system then forwards the aggregated distributed-timing-information to the plurality of nodes. Finally, each node constructs an optimized-convergecast-schedule for the convergecast tree based on the aggregated distributed-timing-information. |
FILED | Friday, November 02, 2007 |
APPL NO | 11/934676 |
ART UNIT | 2477 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/252 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005124 | Then et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Han Wui Then (Urbana, Illinois); Gabriel Walter (Champaign, Illinois); Milton Feng (Champaign, Illinois); Nick Holonyak, Jr. (Urbana, Illinois) |
ABSTRACT | A method for producing wide bandwidth laser emission responsive to high frequency electrical input signals, including the following steps: providing a heterojunction bipolar transistor device having collector, base, and emitter regions; providing at least one quantum size region in the base region, and enclosing at least a portion of the base region in an optical resonant cavity; coupling electrical signals, including the high frequency electrical input signals, with respect to the collector, base and emitter region, to cause laser emission from the transistor device; and reducing the operating beta of the transistor laser device to enhance the optical bandwidth of the laser emission in response to the high frequency electrical signals. |
FILED | Wednesday, October 14, 2009 |
APPL NO | 12/587895 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/46.11 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005176 | Song |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | William S. Song (Lexington, Massachusetts) |
ABSTRACT | Described are nonlinear filter processors having an array of polynomial nonlinear filters including a first polynomial nonlinear filter and a last polynomial nonlinear filter. The first polynomial nonlinear filter has an input terminal for receiving an input data sample. The polynomial nonlinear filters systolically pass the input data sample from the first polynomial nonlinear filter to the last polynomial nonlinear filter. Each polynomial nonlinear filter produces an output data sample based on the input data sample. In addition, each polynomial nonlinear filter other than the last polynomial nonlinear filter systolically passes the output data sample generated by that polynomial nonlinear filter to a neighboring polynomial nonlinear filter. Each polynomial nonlinear filter other than the first polynomial nonlinear filter sums a nonlinearly filtered input data sample produced by that polynomial nonlinear filter with the output data sample received from a neighboring polynomial nonlinear filter. |
FILED | Thursday, February 14, 2008 |
APPL NO | 12/030913 |
ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Pulse or digital communications 375/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005257 | Venetsky et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Larry Venetsky (Mount Laurel, New Jersey); Jeffrey W. Tieman (Leonardtown, Maryland) |
ABSTRACT | A method of identifying a human gesture using a machine includes providing a time sequence of data related to the human gesture; transforming the time sequence of data into waveforms; extracting features from the waveforms; and identifying the human gesture based on the extracted features. |
FILED | Wednesday, July 23, 2008 |
APPL NO | 12/177913 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005332 | Schmidt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Brigham Young University (Provo, Utah) |
INVENTOR(S) | Holger Schmidt (Capitola, California); Aaron Roe Hawkins (Provo, Utah) |
ABSTRACT | An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate. |
FILED | Wednesday, April 02, 2008 |
APPL NO | 12/061165 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/131 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005486 | Pahlavan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
INVENTOR(S) | Kaveh Pahlavan (Newton, Massachusetts); Nayef Al-Sindi (Malden, Massachusetts); Bardia Alavi (Shaker Heights, Ohio) |
ABSTRACT | Methods and systems for configuring ad-hoc networks, especially a self-configuring wireless sensor networks, are described. The network has an initial number of anchors with known positions that broadcast a signal. The signals are received by distributed nodes whose position is not yet known. The nodes rank the received signal based on a Quality of Link (QoL; received signal strength) and compute a Quality of position Estimate (QoE) for the node. The node with the best QoE is elevated to anchor. This process gradually increases the number of available anchors in the network and hence the position accuracy for additional nodes. The system can be used for geolocation of soldiers in the indoor combat, tracking the location of firefighter and other emergency personnel in rescue missions, etc. |
FILED | Tuesday, January 22, 2008 |
APPL NO | 12/009836 |
ART UNIT | 2617 — Optics |
CURRENT CPC | Telecommunications 455/456.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005631 | Barger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
INVENTOR(S) | James E. Barger (Winchester, Massachusetts); Stephen D. Milligan (Stow, Massachusetts); Marshall Seth Brinn (Newton, Massachusetts); Richard J. Mullen (Needham, Massachusetts) |
ABSTRACT | Systems and methods for locating the shooter of supersonic projectiles are described. The system uses at least five, preferably seven, spaced acoustic sensors. Sensor signals are detected for shockwaves and muzzle blast, wherein muzzle blast detection can be either incomplete coming from less than 4 sensor channels, or inconclusive due to lack of signal strength. Shooter range can be determined by an iterative computation and/or a genetic algorithm by minimizing a cost function that includes timing information from both shockwave and muzzle signal channels. Disambiguation is significantly improved over shockwave-only measurements. |
FILED | Friday, March 07, 2008 |
APPL NO | 12/074884 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/60 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005767 | Cassella |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Vincent A. Cassella (W. Springfield, Virginia) |
ABSTRACT | The present invention enables identification of events such as target. From training target event data the present a very large number of clusters are formed for each class based on Euclidean distance using a repetitive k-means clustering process. Features from each cluster are identified by extracting out their dominant eigenvectors. Once all of the dominant eigenvectors have been identified, they define the relevant space of the cluster. New target event data is compared to each cluster by projecting it onto the relevant and noise spaces. The more the data lies within the relevant space and the less it lies within the noise space the more similar the data is to a cluster. The new target event data is then classified based on the training target event data. |
FILED | Friday, June 01, 2007 |
APPL NO | 11/756690 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Artificial intelligence 76/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005839 | Aggarwal et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charu C. Aggarwal (Mohegan Lake, New York); Philip Shi-Lung Yu (Chicago, Illinois) |
ABSTRACT | Techniques are disclosed for aggregation in uncertain data in data processing systems. For example, a method of aggregation in an application that involves an uncertain data set includes the following steps. The uncertain data set along with uncertainty information is obtained. One or more clusters of data points are constructed from the data set. Aggregate statistics of the one or more clusters and uncertainty information are stored. The data set may be data from a data stream. It is realized that the use of even modest uncertainty information during an application such as a data mining process is sufficient to greatly improve the quality of the underlying results. |
FILED | Thursday, February 28, 2008 |
APPL NO | 12/039076 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/737 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 08001672 | Meinke |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Advanced Magnet Lab, Inc (Palm Bay, Florida) |
INVENTOR(S) | Rainer Meinke (Melbourne, Florida) |
ABSTRACT | A method for manufacture of a conductor assembly along a curvilinear axis. The assembly may be of the type which, when conducting current, generates a magnetic field or in which, in the presence of a changing magnetic field, a voltage is induced. In one example, the assembly includes a structure having a curved shape extending along the axis. A surface of the structure is positioned for formation of a channel along the curved shape. The structure is rotated about a second axis. While rotating the structure, a channel is formed in the surface that results in a helical shape in the structure. The channel extends both around and along the first axis. |
FILED | Thursday, June 05, 2008 |
APPL NO | 12/133739 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/605 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002854 | Muradov |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
INVENTOR(S) | Nazim Z. Muradov (Melbourne, Florida) |
ABSTRACT | A novel process and apparatus are disclosed for sustainable CO2-free production of hydrogen and carbon by thermocatalytic decomposition (dissociation, pyrolysis, cracking) of hydrocarbon fuels over carbon-based catalysts in the absence of air and/or water. The apparatus and thermocatalytic process improve the activity and stability of carbon catalysts during the thermocatalytic process and produce both high purity hydrogen (at least, 99.0 volume %) and carbon, from any hydrocarbon fuel, including sulfurous fuels. In a preferred embodiment, production of hydrogen and carbon is achieved by both internal and external activation of carbon catalysts. Internal activation of carbon catalyst is accomplished by recycling of hydrogen-depleted gas containing unsaturated and aromatic hydrocarbons back to the reactor. External activation of the catalyst can be achieved via surface gasification with hot combustion gases during catalyst heating. The process and apparatus can be conveniently integrated with any type of fuel cell to generate electricity. |
FILED | Friday, December 29, 2006 |
APPL NO | 11/648453 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Gas: Heating and illuminating 048/61 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002874 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Membrane Technology and Research, Inc. (Menlo Park, California) |
INVENTOR(S) | Yu Huang (Palo Alto, California); Jennifer Ly (San Jose, California); Tiem Aldajani (San Jose, California); Richard W. Baker (Palo Alto, California) |
ABSTRACT | Processes for dehydrating an organic/water solution by pervaporation or vapor separation using fluorinated membranes. The processes are particularly useful for treating mixtures containing light organic components, such as ethanol, isopropanol or acetic acid. |
FILED | Tuesday, March 06, 2007 |
APPL NO | 11/715245 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/50 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003045 | Muralidharan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Govindarajan Muralidharan (Knoxville, Tennessee); Vinod Kumar Sikka (Oak Ridge, Tennessee); Philip J. Maziasz (Oak Ridge, Tennessee); Roman I. Pankiw (Greensburg, Pennsylvania) |
ABSTRACT | A cast, austenitic steel composed essentially of, expressed in weight percent of the total composition, about 0.4 to about 0.7 C, about 20 to about 30 Cr, about 20 to about 30 Ni, about 0.5 to about 1 Mn, about 0.6 to about 2 Si, about 0.05 to about 1 Nb, about 0.05 to about 1 W, about 0.05 to about 1.0 Mo, balance Fe, the steel being essentially free of Ti and Co, the steel characterized by at least one microstructural component selected from the group consisting of MC, M23C6, and M(C, N). |
FILED | Friday, June 04, 2010 |
APPL NO | 12/793930 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Alloys or metallic compositions 420/53 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003070 | Fox et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Robert V. Fox (Idaho Falls, Idaho); Rene G. Rodriguez (Pocatello, Idaho); Joshua Pak (Pocatello, Idaho) |
ABSTRACT | Single source precursors are subjected to carbon dioxide to form particles of material. The carbon dioxide may be in a supercritical state. Single source precursors also may be subjected to supercritical fluids other than supercritical carbon dioxide to form particles of material. The methods may be used to form nanoparticles. In some embodiments, the methods are used to form chalcopyrite materials. Devices such as, for example, semiconductor devices may be fabricated that include such particles. Methods of forming semiconductor devices include subjecting single source precursors to carbon dioxide to form particles of semiconductor material, and establishing electrical contact between the particles and an electrode. |
FILED | Thursday, March 13, 2008 |
APPL NO | 12/047956 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/508 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003073 | Pez et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Air Products and Chemicals, Inc. (Allentown, Pennsylvania) |
INVENTOR(S) | Guido Peter Pez (Allentown, Pennsylvania); Alan Charles Cooper (Macungie, Pennsylvania); Aaron Raymond Scott (Allentown, Pennsylvania) |
ABSTRACT | Processes are provided for the storage and release of hydrogen by means of dehydrogenation of hydrogen carrier compositions where at least part of the heat of dehydrogenation is provided by a hydrogen-reversible selective oxidation of the carrier. Autothermal generation of hydrogen is achieved wherein sufficient heat is provided to sustain the at least partial endothermic dehydrogenation of the carrier at reaction temperature. The at least partially dehydrogenated and at least partially selectively oxidized liquid carrier is regenerated in a catalytic hydrogenation process where apart from an incidental employment of process heat, gaseous hydrogen is the primary source of reversibly contained hydrogen and the necessary reaction energy. |
FILED | Tuesday, April 15, 2008 |
APPL NO | 12/103205 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/651 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003220 | Melechko et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Anatoli V. Melechko (Oak Ridge, Tennessee); Timothy E. McKnight (Greenback, Tennessee); Michael A. Guillorn (Ithaca, New York); Bojan Ilic (Ithaca, New York); Vladimir I. Merkulov (Knoxville, Tennessee); Mitchel J. Doktycz (Knoxville, Tennessee); Douglas H. Lowndes (Knoxville, Tennessee); Michael L. Simpson (Knoxville, Tennessee) |
ABSTRACT | Methods, manufactures, machines and compositions are described for nanotransfer and nanoreplication using deterministically grown sacrificial nanotemplates. An apparatus, includes a substrate and a nanoreplicant structure coupled to a surface of the substrate. |
FILED | Tuesday, November 13, 2007 |
APPL NO | 11/985395 |
ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/446 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003404 | Rotello et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Vincent Rotello (Belchertown, Massachusetts); Uwe Bunz (Atlanta, Georgia); Ronnie Phillips (Atlanta, Georgia); Oscar Miranda (Amherst, Massachusetts); Chang-Cheng You (Waltham, Massachusetts) |
ABSTRACT | Compositions, methods and related apparatus, as can be used for selective pathogen detection and identification. |
FILED | Monday, November 17, 2008 |
APPL NO | 12/313137 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003497 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Peidong Yang (El Cerrito, California); Heonjin Choi (Seoul, South Korea); Sangkwon Lee (Daejeon, South Korea); Rongrui He (Albany, California); Yanfeng Zhang (El Cerrito, California); Tevye Kuykendal (Berkeley, California); Peter Pauzauskie (Berkeley, California) |
ABSTRACT | A method for is disclosed for fabricating diluted magnetic semiconductor (DMS) nanowires by providing a catalyst-coated substrate and subjecting at least a portion of the substrate to a semiconductor, and dopant via chloride-based vapor transport to synthesize the nanowires. Using this novel chloride-based chemical vapor transport process, single crystalline diluted magnetic semiconductor nanowires Ga1-xMnxN (x=0.07) were synthesized. The nanowires, which have diameters of ˜10 nm to 100 nm and lengths of up to tens of micrometers, show ferromagnetism with Curie temperature above room temperature, and magnetoresistance up to 250 Kelvin. |
FILED | Thursday, June 29, 2006 |
APPL NO | 11/480280 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003571 | Stan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Liliana Stan (Los Alamos, New Mexico); Quanxi Jia (Los Alamos, New Mexico); Stephen R. Foltyn (Los Alamos, New Mexico) |
ABSTRACT | A composite structure is provided including a base substrate, an IBAD oriented material upon the base substrate, and a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material. Additionally, an article is provided including a base substrate, an IBAD oriented material upon the base substrate, a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material, and a thick film upon the cubic metal oxide material. Finally, a superconducting article is provided including a base substrate, an IBAD oriented material upon the base substrate, a cubic metal oxide material selected from the group consisting of rare earth zirconates and rare earth hafnates upon the IBAD oriented material, and an yttrium barium copper oxide material upon the cubic metal oxide material. |
FILED | Tuesday, August 07, 2007 |
APPL NO | 11/890812 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Superconductor technology: Apparatus, material, process 55/237 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003730 | Celina |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Mathias C. Celina (Albuquerque, New Mexico) |
ABSTRACT | An epoxy resin mixture with at least one epoxy resin of between approximately 60 wt % and 90 wt %, a maleic anhydride of between approximately 1 wt % and approximately 30 wt %, and an imidazole catalyst of less than approximately 2 wt % where the resin mixture is formed from at least one epoxy resin with a 1-30 wt % maleic anhydride compound and an imidazole catalyst at a temperature sufficient to keep the maleic anhydride compound molten, the resin mixture reacting to form a foaming resin which can then be cured at a temperature greater than 50° C. to form an epoxy foam. |
FILED | Tuesday, December 16, 2008 |
APPL NO | 12/335925 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 525/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003855 | Somerville et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Institution of Washington (Washington, District of Columbia); Monsanto Company, Inc. (St. Louis, Missouri) |
INVENTOR(S) | Chris Somerville (Portola Valley, California); Pierre Broun (Burlingame, California); Frank van de Loo (Weston, Australia); Sekhar S. Boddupalli (Manchester, Michigan) |
ABSTRACT | This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described. |
FILED | Thursday, September 27, 2007 |
APPL NO | 11/905067 |
ART UNIT | 1638 — Organic Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/306 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003937 | Kertesz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle (Oak Ridge, Tennessee) |
INVENTOR(S) | Vilmos Kertesz (Knoxville, Tennessee); Gary Van Berkel (Clinton, Tennessee) |
ABSTRACT | An electrospray ion (ESI) source and method capable of ionizing an analyte molecule without oxidizing or reducing the analyte of interest. The ESI source can include an emitter having a liquid conduit, a working electrode having a liquid contacting surface, a spray tip, a secondary working electrode, and a charge storage coating covering partially or fully the liquid contacting surface of the working electrode. The liquid conduit, the working electrode and the secondary working electrode can be in liquid communication. The electrospray ion source can also include a counter electrode proximate to, but separated from, said spray tip. The electrospray ion source can also include a power system for applying a voltage difference between the working electrodes and a counter-electrode. The power system can deliver pulsed voltage changes to the working electrodes during operation of said electrospray ion source to minimize the surface potential of the charge storage coating. |
FILED | Thursday, September 25, 2008 |
APPL NO | 12/237892 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/288 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003982 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Zhong L. Wang (Marietta, Georgia); Sheng Xu (Atlanta, Georgia) |
ABSTRACT | An electric power generator includes a first conductive layer, a plurality of semiconducting piezoelectric nanostructures, a second conductive layer and a plurality of conductive nanostructures. The first conductive layer has a first surface from which the semiconducting piezoelectric nanostructures extend. The second conductive layer has a second surface and is parallel to the first conductive layer so that the second surface faces the first surface of the first conductive layer. The conductive nanostructures depend downwardly therefrom. The second conductive layer is spaced apart from the first conductive layer at a distance so that when a force is applied, the semiconducting piezoelectric nanostructures engage the conductive nanostructures so that the piezoelectric nanostructures bend, thereby generating a potential difference across the at semiconducting piezoelectric nanostructures and also thereby forming a Schottky barrier between the semiconducting piezoelectric nanostructures and the conductive nanostructures. |
FILED | Thursday, December 18, 2008 |
APPL NO | 12/338131 |
ART UNIT | 2811 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/43 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004140 | Alexander et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | James Pellegrino Alexander (Ballston Lake, New York); Ayman Mohamed Fawzi EL-Refaie (Niskayuna, New York); Murtuza Lokhandwalla (Clifton Park, New York); Manoj Ramprasad Shah (Latham, New York); Jeremy Daniel VanDam (West Coxsackie, New York) |
ABSTRACT | An internal permanent magnet (IPM) machine is provided. The IPM machine includes a stator assembly and a stator core. The stator core also includes multiple stator teeth. The stator assembly is further configured with stator windings to generate a stator magnetic field when excited with alternating currents and extends along a longitudinal axis with an inner surface defining a cavity. The IPM machine also includes a rotor assembly and a rotor core. The rotor core is disposed inside the cavity and configured to rotate about the longitudinal axis. The rotor assembly further includes a shaft. The shaft further includes multiple protrusions alternately arranged relative to multiple bottom structures provided on the shaft. The rotor assembly also includes multiple stacks of laminations disposed on the protrusions and dovetailed circumferentially around the shaft. The rotor assembly further includes multiple pair of permanent magnets for generating a magnetic field, which magnetic field interacts with the stator magnetic field to produce a torque. The multiple pair of permanent magnets are disposed between the stacks. The rotor assembly also includes multiple middle wedges mounted between each pair of the multiple permanent magnets. |
FILED | Thursday, April 30, 2009 |
APPL NO | 12/432894 |
ART UNIT | 2834 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/156.560 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 08003008 | Huebner et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
INVENTOR(S) | Christopher F. Huebner (Clemson, South Carolina); David D. Evanoff (Cullowhee, North Carolina); Joseph B. Carroll (Bradford, Massachusetts); Stephan H. Foulger (Clemson, South Carolina) |
ABSTRACT | Color-tailored and white-light emitting polymer colloid-based OLEDs are disclosed. Devices include electroluminescent (EL) colloidal conductive polymer systems that can include EL dyes or other EL materials. Systems can sequester multiple EL components in different colloids in a single emissive layer of an EL device with little or no appreciable energy transfer between colloids. Devices can exhibit tailored emissions over a broad range of wavelengths through mixing of, e.g., red, green and blue PLED colloids. Disclosed methods including incorporation of one or more electroluminescent dyes into a semiconductive EL polymer colloid that can isolate the dyes and prevent energy transfer while retaining individual color emission. |
FILED | Wednesday, October 08, 2008 |
APPL NO | 12/247270 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Compositions 252/301.160 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003374 | Heeger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Alan J. Heeger (Santa Barbara, California); Chunhai Fan (Shanghai, China PRC); Kevin Plaxco (Santa Barbara, California) |
ABSTRACT | A reagentless, reusable bioelectronic DNA, or other oligonucleotide sequence sensor is disclosed. The sensor includes an oligonucleotide (aptamer) probe tagged with a electroactive, redoxable moiety, self-assembled on or near an electrode. This surface-confined oligonucleotide (aptamer) probe structure undergoes hybridization-induced conformational change in the presence of the target which changes the electron-transfer distance between the redoxable moiety and the electrode thereby providing a detectable signal change. In an alternative embodiment, the target can harbor the redoxable moiety. |
FILED | Friday, July 29, 2005 |
APPL NO | 11/193318 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003397 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
INVENTOR(S) | Qian Wang (Columbia, South Carolina); Siqi Li (Columbia, South Carolina) |
ABSTRACT | A polymeric sensing fluid for detecting the presence of glucose and systems and methods of its use are generally disclosed. The polymeric sensing fluid includes a polymer in a solvent (e.g., an aqueous solvent). The polymer has a plurality of boronic acid moieties extending from its polymeric backbone. As such, the polymeric sensing fluid is configured to increase in viscosity upon addition of glucose due to crosslinking between the boronic acid moieties of the polymer and glucose. |
FILED | Thursday, January 29, 2009 |
APPL NO | 12/361825 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/95 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003404 | Rotello et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Vincent Rotello (Belchertown, Massachusetts); Uwe Bunz (Atlanta, Georgia); Ronnie Phillips (Atlanta, Georgia); Oscar Miranda (Amherst, Massachusetts); Chang-Cheng You (Waltham, Massachusetts) |
ABSTRACT | Compositions, methods and related apparatus, as can be used for selective pathogen detection and identification. |
FILED | Monday, November 17, 2008 |
APPL NO | 12/313137 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003497 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Peidong Yang (El Cerrito, California); Heonjin Choi (Seoul, South Korea); Sangkwon Lee (Daejeon, South Korea); Rongrui He (Albany, California); Yanfeng Zhang (El Cerrito, California); Tevye Kuykendal (Berkeley, California); Peter Pauzauskie (Berkeley, California) |
ABSTRACT | A method for is disclosed for fabricating diluted magnetic semiconductor (DMS) nanowires by providing a catalyst-coated substrate and subjecting at least a portion of the substrate to a semiconductor, and dopant via chloride-based vapor transport to synthesize the nanowires. Using this novel chloride-based chemical vapor transport process, single crystalline diluted magnetic semiconductor nanowires Ga1-xMnxN (x=0.07) were synthesized. The nanowires, which have diameters of ˜10 nm to 100 nm and lengths of up to tens of micrometers, show ferromagnetism with Curie temperature above room temperature, and magnetoresistance up to 250 Kelvin. |
FILED | Thursday, June 29, 2006 |
APPL NO | 11/480280 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003852 | Gaxiola et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Roberto A. Gaxiola (Tempe, Arizona); Gerald R. Fink (Chestnut Hill, Massachusetts); Seth L. Alper (Boston, Massachusetts) |
ABSTRACT | Transgenic plants are described which are engineered to overexpress vacuolar H+-PPase. Plants such as tobacco and petunia transformed with A. Thaliana AVP-1 are shown to have increased meristematic activity resulting in larger leaves, stem, flower, fruit, root structures, increased salt tolerance, enhanced drought and freeze tolerance. Methods of making such plants are also described. |
FILED | Tuesday, March 31, 2009 |
APPL NO | 12/384115 |
ART UNIT | 1638 — Organic Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/295 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003855 | Somerville et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Carnegie Institution of Washington (Washington, District of Columbia); Monsanto Company, Inc. (St. Louis, Missouri) |
INVENTOR(S) | Chris Somerville (Portola Valley, California); Pierre Broun (Burlingame, California); Frank van de Loo (Weston, Australia); Sekhar S. Boddupalli (Manchester, Michigan) |
ABSTRACT | This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described. |
FILED | Thursday, September 27, 2007 |
APPL NO | 11/905067 |
ART UNIT | 1638 — Organic Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/306 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004474 | Makarov et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Physical Sciences, Inc. (Andover, Massachusetts) |
INVENTOR(S) | Sergey N. Makarov (Holden, Massachusetts); Francesca Scire-Scappuzzo (Lexington, Massachusetts) |
ABSTRACT | Described is an apparatus and method for reducing noise in an information bearing signal is provided. A feeding element receives dual-polarized wideband electromagnetic signals. The feeding element is coupled to a Non-Cutoff Frequency Selective Surface ground plane. The Non-Cutoff Frequency Selective Surface ground plane allows for a line-of-sight signal and a surface wave to cancel. The Non-Cutoff Frequency Selective Surface ground plane can be a metal plate with a plurality of corrugations. The corrugations can be concentric rings, each corrugation having a predetermined height and a predetermined spacing from adjacent corrugations. |
FILED | Wednesday, September 17, 2008 |
APPL NO | 12/212065 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/909 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004762 | Cathey, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents Of The University Of Colorado, a body corporate (Denver, Colorado) |
INVENTOR(S) | Wade Thomas Cathey, Jr. (Boulder, Colorado); Edward Raymond Dowski, Jr. (Lafayette, Colorado) |
ABSTRACT | Systems and methods for generating an optical image include forming an optical image with at least one optical element of an optical imager while modifying wavefront phase. Modifying the phase does not reduce an optical bandpass limited by an aperture of the optical imager. The systems and methods also include detecting the optical image over a range of spatial frequencies such that there are no zeros in an optical transfer function of the optical imager over detected spatial frequencies within the optical bandpass and over an extended depth of focus that is larger than a depth of focus occurring without modifying wavefront phase. |
FILED | Monday, October 13, 2008 |
APPL NO | 12/250343 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/558 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005114 | Mishra et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Arunesh Mishra (Mountain View, California); Suman Banerjee (Madison, Wisconsin) |
ABSTRACT | A transceiver for wireless data transmission provides for variable bit rates within a packet (intra-packet rate changes) to provide a high-speed adaptation to variations in link quality useful for continuous mobility applications. Intra-packet rate variations may be obtained with standard hardware by remapping payload data to a subset of the hardware transmission constellation symbols. |
FILED | Tuesday, September 08, 2009 |
APPL NO | 12/555353 |
ART UNIT | 2474 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/472 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005332 | Schmidt et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Brigham Young University (Provo, Utah) |
INVENTOR(S) | Holger Schmidt (Capitola, California); Aaron Roe Hawkins (Provo, Utah) |
ABSTRACT | An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate. |
FILED | Wednesday, April 02, 2008 |
APPL NO | 12/061165 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/131 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005526 | Martin et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | David C. Martin (Ann Arbor, Michigan); Sarah Richardson-Burns (Ypsilanti, Michigan); Donghwan Kim (Ann Arbor, Michigan); Jeffrey L. Hendricks (Ann Arbor, Michigan); Laura Povlich (Taylor, Michigan); Mohamad Reza Abidian (Ann Arbor, Michigan); Matthew Meier (Ann Arbor, Michigan) |
ABSTRACT | Bioelectrodes having enhanced biocompatible and biomimetic features are provided. Methods of making and using the bioelectrodes are further provided. A biologically integrated bioelectrode device and method for detecting electronic signals using a bioelectrode comprising a first electrically conductive substrate and a biological component. The bioelectrode also comprises a conductive polymer electrically coupling the first electrically conductive substrate and the biological component to define a bioelectrode. The bioelectrode can transmit or receive an electrical signal between the electrically conductive substrate and the biological component and conductive polymer. |
FILED | Wednesday, August 30, 2006 |
APPL NO | 11/512479 |
ART UNIT | 3739 — Optics |
CURRENT CPC | Surgery 6/372 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005975 | Liu |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Polytechnic Institute of New York University (Brooklyn, New York) |
INVENTOR(S) | Yong Liu (Secaucus, New Jersey) |
ABSTRACT | A new P2P streaming method and apparatus disseminates video chunks to all peers with the minimum (or at least reduced) delay. After obtaining a new video chunk, a peer keeps transmitting (uploading) that video chunk to other peers until all peers receive it. The approach quickly increases the aggregate bandwidth that can be utilized to transmit a video chunk. For example, the aggregate peer bandwidth used to transmit a video chunk can double every time slot. For a homogeneous P2P streaming system with N peers, a time slot is defined as a unit of the single chunk transmission delay between two peers. Using the P2P streaming method, a video chunk can be disseminated to all peers within 1+log2 N time slots. |
FILED | Wednesday, October 06, 2010 |
APPL NO | 12/898762 |
ART UNIT | 2453 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/231 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 08001828 | Hunter et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Gary W. Hunter (Oberlin, Ohio); Jennifer C. Xu (Olmsted Township, Ohio); Dorothy Lukco (Sagamore Hills, Ohio) |
ABSTRACT | A miniaturized Schottky diode hydrogen and hydrocarbon sensor and the method of making same is disclosed and claimed. The sensor comprises a catalytic metal layer, such as palladium, a silicon carbide substrate layer and a thin barrier layer in between the catalytic and substrate layers made of palladium oxide (PdOx ). This highly stable device provides sensitive gas detection at temperatures ranging from at least 450 to 600° C. The barrier layer prevents reactions between the catalytic metal layer and the substrate layer. Conventional semiconductor fabrication techniques are used to fabricate the small-sized sensors. The use of a thicker palladium oxide barrier layer for other semiconductor structures such as a capacitor and transistor structures is also disclosed. |
FILED | Friday, June 20, 2008 |
APPL NO | 12/143139 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/31.60 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08002219 | Camarda et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Charles J. Camarda (League City, Texas); Stephen J. Scotti (Grafton, Virginia); Pieter G. Buning (Yorktown, Virginia); Steven X. S. Bauer (Yorktown, Virginia); Walter C. Engelund (Seaford, Virginia); David M. Schuster (Williamsburg, Virginia) |
ABSTRACT | An annular fairing having aerodynamic, thermal, structural and acoustic attributes couples a launch abort motor to a space vehicle having a payload of concern mounted on top of a rocket propulsion system. A first end of the annular fairing is fixedly attached to the launch abort motor while a second end of the annular fairing is attached in a releasable fashion to an aft region of the payload. The annular fairing increases in diameter between its first and second ends. |
FILED | Friday, November 16, 2007 |
APPL NO | 11/941119 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/171.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003055 | Muradov |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
INVENTOR(S) | Nazim Muradov (Melbourne, Florida) |
ABSTRACT | Methods, processes and compositions are provided for a visual or chemochromic hydrogen-detector with variable or tunable reversible color change. The working temperature range for the hydrogen detector is from minus 100° C. to plus 500° C. A hydrogen-sensitive pigment, including, but not limited to, oxides, hydroxides and polyoxo-compounds of tungsten, molybdenum, vanadium, chromium and combinations thereof, is combined with nano-sized metal activator particles and preferably, coated on a porous or woven substrate. In the presence of hydrogen, the composition rapidly changes its color from white or light-gray or light-tan to dark gray, navy-blue or black depending on the exposure time and hydrogen concentration in the medium. After hydrogen exposure ceases, the original color of the hydrogen-sensitive pigment is restored, and the visual hydrogen detector can be used repeatedly. By changing the composition of the hydrogen-sensitive pigment, the time required for its complete regeneration is varied from a few seconds to several days. |
FILED | Wednesday, February 27, 2008 |
APPL NO | 12/038210 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/86 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004364 | Sims, III et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | William Herbert Sims, III (New Market, Alabama); Donald Gregory Chavers (Somerville, Alabama); James J. Richeson (Madison, Alabama) |
ABSTRACT | A high power, high frequency, solid state power amplifier system includes a plurality of input multiple port splitters for receiving a high-frequency input and for dividing the input into a plurality of outputs and a plurality of solid state amplifier units. Each amplifier unit includes a plurality of amplifiers, and each amplifier is individually connected to one of the outputs of multiport splitters and produces a corresponding amplified output. A plurality of multiport combiners combine the amplified outputs of the amplifiers of each of the amplifier units to a combined output. Automatic level control protection circuitry protects the amplifiers and maintains a substantial constant amplifier power output. |
FILED | Thursday, July 26, 2007 |
APPL NO | 11/828563 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Amplifiers 330/295 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004558 | Prechtl et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Axis Engineering Technologies, Inc. (Devens, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Eric F. Prechtl (Groton, Massachusetts); Raymond J. Sedwick (Somerville, Massachusetts); Eric M. Jonas (Cambridge, Massachusetts) |
ABSTRACT | A stereoscopic imaging system incorporates a plurality of imaging devices or cameras to generate a high resolution, wide field of view image database from which images can be combined in real time to provide wide field of view or panoramic or omni-directional still or video images. |
FILED | Friday, April 07, 2006 |
APPL NO | 11/400029 |
ART UNIT | 2622 — Selective Visual Display Systems |
CURRENT CPC | Television 348/48 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005314 | Ortyn et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Amnis Corporation (Seattle, Washington) |
INVENTOR(S) | William Ortyn (Bainbridge Island, Washington); David Basiji (Seattle, Washington); Keith Frost (Seattle, Washington); Luchuan Liang (Woodinville, Washington); Richard Bauer (Kirkland, Washington); Brian Hall (Seattle, Washington); David Perry (Woodinville, Washington) |
ABSTRACT | A high speed, high-resolution flow imaging system is modified to achieve extended depth of field imaging. An optical distortion element is introduced into the flow imaging system. Light from an object, such as a cell, is distorted by the distortion element, such that a point spread function (PSF) of the imaging system is invariant across an extended depth of field. The distorted light is spectrally dispersed, and the dispersed light is used to simultaneously generate a plurality of images. The images are detected, and image processing is used to enhance the detected images by compensating for the distortion, to achieve extended depth of field images of the object. The post image processing preferably involves de-convolution, and requires knowledge of the PSF of the imaging system, as modified by the optical distortion element. |
FILED | Monday, December 11, 2006 |
APPL NO | 11/609269 |
ART UNIT | 2447 — Computer Networks |
CURRENT CPC | Image analysis 382/275 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 08002919 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Ebert Composites Corporation (Chula Vista, California) |
INVENTOR(S) | David W. Johnson (San Diego, California); Scott A. Garrett (San Diego, California); James H. Hook (Alpine, California); Stephen G. Moyers (Jamul, California) |
ABSTRACT | A method of inserting z-axis reinforcing fibers into a multi-layer composite laminate. Layers of material made up of z-axis fiber and y-axis fibers are automatically transported into a z-fiber deposition machine having a housing with upper and lower surfaces. Z-axis apertures are formed in the respective upper and lower surfaces. An elongated solid rod having a tapered front tip is aligned in close proximity to the aperture in the bottom surface. The rod is first rotated by a motor and then actuated upwardly completely through the thickness of the layer of x-y material by an actuator. A first hollow tube having a z-axis is axially aligned with the aperture in the top surface and a fiber bundle is threaded downwardly through a first hollow tube to a position adjacent its bottom end. The z-fiber deposition machine has structure to feed a predetermined length of the fiber bundle downwardly through the first hollow tube so that it follows the pathway in the x-y material formed by the rod which is now withdrawn downwardly through the aperture in the bottom wall. The z-axis fiber is thus deposited into the x-y material. The top end of the z-axis fiber is then severed and the x-y material is then advanced a predetermined distance to complete the cycle and is, thus, set to be repeated. |
FILED | Monday, June 16, 2008 |
APPL NO | 12/140121 |
ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/91 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003051 | Bedingham et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
INVENTOR(S) | William Bedingham (Woodbury, Minnesota); James E. Aysta (Stillwater, Minnesota); Barry W. Robole (Woodville, Wisconsin) |
ABSTRACT | Sample processing systems for processing sample materials located in sample processing devices that are separate from the system are disclosed. The sample processing systems include a rotating base plate with raised and/or non-planar thermal structures on which the sample processing devices are located during operation of the systems. The systems may also include structure to urge the sample processing devices against the base plate and thermal structures. |
FILED | Thursday, June 25, 2009 |
APPL NO | 12/491959 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/64 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003769 | Fisher et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Applied Biosystems, LLC (Carlsbad, California) |
INVENTOR(S) | Peter Virgil Fisher (El Granada, California); Shaheer Khan (Foster City, California); Paolo Vatta (San Mateo, California) |
ABSTRACT | The invention provides novel dye-labeled ribonucleotide analogs and methods for synthesizing those analogs. The compounds of the invention are especially useful for DNA sequencing by the polymerase chain reaction. |
FILED | Monday, January 25, 2010 |
APPL NO | 12/656305 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/4.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003807 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
INVENTOR(S) | Yuning Li (Mississauga, Canada); Beng S. Ong (Mississauga, Canada); Yiliang Wu (Mississauga, Canada); Ping Liu (Mississauga, Canada) |
ABSTRACT | An electronic device including a compound comprising at least one type of an optionally substituted indolocarbazole moiety and at least one divalent linkage. |
FILED | Wednesday, June 02, 2010 |
APPL NO | 12/791928 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 548/416 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003926 | Bedingham et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
INVENTOR(S) | William Bedingham (Woodbury, Minnesota); Raj Rajagopal (Woodbury, Minnesota); Barry W. Robole (Woodinville, Wisconsin) |
ABSTRACT | Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is rotated during heating of the sample materials. |
FILED | Friday, September 05, 2008 |
APPL NO | 12/205170 |
ART UNIT | 3742 — Organic Chemistry |
CURRENT CPC | Electric heating 219/627 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 08003136 | Beavers |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Randy Beavers (Dalton, Georgia) |
ABSTRACT | The present invention relates generally to herbal materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. Particularly, the present invention relates generally to Hydrastis canadensis (goldenseal) materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. More particularly, the present invention relates a process which allows the standardization of the product to specified levels of bioactivity in both hydro-alcoholic tinctures and solid extracts in the processing of goldenseal materials to produce extracts which qualify as pharmaceutical grade compositions which are suitable for use in clinical or veterinary settings to treat and/or ameliorate diseases, disorders or conditions. |
FILED | Tuesday, July 31, 2007 |
APPL NO | 11/882270 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/725 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003328 | Rosenkrans, Jr. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
INVENTOR(S) | Charles F. Rosenkrans, Jr. (Springdale, Arkansas) |
ABSTRACT | Methods of predicting the phenotype of a trait in a bovine subject are provided. The methods include obtaining information about polynucleotide sequences specifically regarding the identity of the nucleotides present at one or more identified single nucleotide polymorphisms and using this information to make predictions regarding the trait in the subject. Also provided are kits for and methods of determining the nucleotide present in a bovine subject at a position in which a single nucleotide polymorphism is correlated with a trait. |
FILED | Monday, February 02, 2009 |
APPL NO | 12/364145 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08004292 | Backus et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Elaine Backus (Clovis, California); William Bennett (Otterville, Missouri) |
ABSTRACT | An electrical penetration graph (EPG) system includes a monitoring device with a buffered and stabilized voltage source assembly and a buffered internal amplifier with switched gain control. The system also includes a head stage amplifier. During the EPG process, the voltage source assembly directs an electrical current through a feeding insect. As the current passes through the insect, the insect's feeding process modulates the current and creates voltage waveform data. A head stage amplifier with selectable input resistance receives and amplifies the voltage waveform data. The data is transmitted back to the monitoring device where it is manipulated and further amplified by the monitoring device internal amplifier assembly. The waveform data is then transmitted to a controller and ultimately to an output device where the data is displayed. |
FILED | Wednesday, October 22, 2008 |
APPL NO | 12/256168 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/692 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 08002874 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Membrane Technology and Research, Inc. (Menlo Park, California) |
INVENTOR(S) | Yu Huang (Palo Alto, California); Jennifer Ly (San Jose, California); Tiem Aldajani (San Jose, California); Richard W. Baker (Palo Alto, California) |
ABSTRACT | Processes for dehydrating an organic/water solution by pervaporation or vapor separation using fluorinated membranes. The processes are particularly useful for treating mixtures containing light organic components, such as ethanol, isopropanol or acetic acid. |
FILED | Tuesday, March 06, 2007 |
APPL NO | 11/715245 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/50 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003136 | Beavers |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Randy Beavers (Dalton, Georgia) |
ABSTRACT | The present invention relates generally to herbal materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. Particularly, the present invention relates generally to Hydrastis canadensis (goldenseal) materials and methods for making such materials in medicinally useful and pharmaceutically acceptable forms. More particularly, the present invention relates a process which allows the standardization of the product to specified levels of bioactivity in both hydro-alcoholic tinctures and solid extracts in the processing of goldenseal materials to produce extracts which qualify as pharmaceutical grade compositions which are suitable for use in clinical or veterinary settings to treat and/or ameliorate diseases, disorders or conditions. |
FILED | Tuesday, July 31, 2007 |
APPL NO | 11/882270 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/725 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005527 | Zelenchuk |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Luma Imaging Corporation (San Diego, California) |
INVENTOR(S) | Alex R. Zelenchuk (Stoughton, Massachusetts) |
ABSTRACT | A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at three selected wavelengths, one of which corresponds to an isosbestic point. In one example, the isosbestic point occurs at about 431 nm. The intensities of the observed signals are normalized using the 431 nm intensity. A score is determined using the ratios in a discriminant analysis. The tissue under examination is resected or not, based on the diagnosis of disease or health, according to the outcome of the discriminant analysis. |
FILED | Wednesday, December 12, 2007 |
APPL NO | 11/955165 |
ART UNIT | 3737 — Optics |
CURRENT CPC | Surgery 6/407 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 08003385 | Sukumar et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sanofi Pasteur Vax Design Corp. (Orlando, Florida) |
INVENTOR(S) | Selva Sukumar (Berkeley, California); Mohey Eldin M. El Shikh (Richmond, Virginia); John G. Tew (Mechanicsville, Virginia); Guzman Sanchez-Schmitz (Orlando, Florida); Donald Drake, III (Orlando, Florida); Luis Mosquera (Oviedo, Florida); Conan Li (Los Altos, California); Anatoly M. Kachurin (Orlando, Florida); Russell Higbee (Orlando, Florida); Heather Fahlenkamp (Cleveland, Oklahoma); Eric Mishkin (Winter Springs, Florida); William L. Warren (Orlando, Florida) |
ABSTRACT | The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. |
FILED | Wednesday, February 17, 2010 |
APPL NO | 12/707563 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/326 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003387 | Sukumar et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sanofi Pasteur Vaxdesign Corp. (Orlando, Florida) |
INVENTOR(S) | Selva Sukumar (Berkeley, California); Mohey Eldin M. El Shikh (Richmond, Virginia); John G. Tew (Mechanicsville, Virginia); Guzman Sanchez-Schmitz (Orlando, Florida); Donald Drake, III (Orlando, Florida); Luis Mosquera (Oviedo, Florida); Eric Mishkin (Winter Springs, Florida); Anatoly M. Kachurin (Orlando, Florida); Russell Higbee (Orlando, Florida); Conan Li (Los Altos, California); William L. Warren (Orlando, Florida); Heather Fahlenkamp (Cleveland, Oklahoma) |
ABSTRACT | The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. |
FILED | Thursday, December 21, 2006 |
APPL NO | 11/642938 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 08003937 | Kertesz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle (Oak Ridge, Tennessee) |
INVENTOR(S) | Vilmos Kertesz (Knoxville, Tennessee); Gary Van Berkel (Clinton, Tennessee) |
ABSTRACT | An electrospray ion (ESI) source and method capable of ionizing an analyte molecule without oxidizing or reducing the analyte of interest. The ESI source can include an emitter having a liquid conduit, a working electrode having a liquid contacting surface, a spray tip, a secondary working electrode, and a charge storage coating covering partially or fully the liquid contacting surface of the working electrode. The liquid conduit, the working electrode and the secondary working electrode can be in liquid communication. The electrospray ion source can also include a counter electrode proximate to, but separated from, said spray tip. The electrospray ion source can also include a power system for applying a voltage difference between the working electrodes and a counter-electrode. The power system can deliver pulsed voltage changes to the working electrodes during operation of said electrospray ion source to minimize the surface potential of the charge storage coating. |
FILED | Thursday, September 25, 2008 |
APPL NO | 12/237892 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/288 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08005839 | Aggarwal et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charu C. Aggarwal (Mohegan Lake, New York); Philip Shi-Lung Yu (Chicago, Illinois) |
ABSTRACT | Techniques are disclosed for aggregation in uncertain data in data processing systems. For example, a method of aggregation in an application that involves an uncertain data set includes the following steps. The uncertain data set along with uncertainty information is obtained. One or more clusters of data points are constructed from the data set. Aggregate statistics of the one or more clusters and uncertainty information are stored. The data set may be data from a data stream. It is realized that the use of even modest uncertainty information during an application such as a data mining process is sufficient to greatly improve the quality of the underlying results. |
FILED | Thursday, February 28, 2008 |
APPL NO | 12/039076 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/737 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 08003324 | Dudley, Jr. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | U.S. Department of Veterans Affairs (Washington, District of Columbia); Emory University (Atlanta, Georgia) |
INVENTOR(S) | Samuel C. Dudley, Jr. (Chicago, Illinois) |
ABSTRACT | The present invention relates to the use of oxidized nicotinamide adenine dinucleotide (NAD+) or of its reduced form, NADH, as sodium channel modulators. The present invention also relates to the use of compositions containing NAD+ or NADH to treat conditions associated with sodium channel current, such as arrhythmia. NAD+ is found to increase sodium channel current, while NADH is found to decrease sodium channel current. Thus, conditions that are associated with decreased sodium channel current can be treated with NAD+, while conditions that is associated with increased sodium channel current can be treated with NADH. |
FILED | Friday, October 17, 2008 |
APPL NO | 12/289005 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 08005568 | Hamilton |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Daryl Hamilton (Hyattsville, Maryland) |
ABSTRACT | A method of tracking trays through a delivery system. The method comprises: generating an enhanced label, the enhanced label comprising a routing code and a label unique identifier, the enhanced label being applied to the tray; associating a tray with a container, the container having a container unique identifier; and receiving a load container scan, the load container scan associating the container unique identifier with the enhanced label. |
FILED | Friday, April 02, 2004 |
APPL NO | 10/817574 |
ART UNIT | 3627 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Data processing: Generic control systems or specific applications 7/225 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 08001826 | Schwarz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Dwight Schwarz (Sahuarita, Arizona); Mark J. Kocan (Tucson, Arizona) |
ABSTRACT | An impact testing system for determining the shock response of a test structure includes a mass (e.g., a spherical steel ball) and a potential energy storage system (e.g., a spring-loaded mechanism) configured to store mechanical energy and, upon actuation, release the stored mechanical energy in the form of kinetic energy. A hold-and-release mechanism (such as a permanent magnet) is configured to releasably couple the mass to the potential energy storage system and impart linear momentum to the mass in connection with the kinetic energy such that the mass impinges upon the test structure. The shock response can then be determined and displayed to a user. |
FILED | Tuesday, May 26, 2009 |
APPL NO | 12/472124 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/12.50 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08003778 | Paul et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | John H. Paul (St. Petersburg, Florida); Mike Gray (St. Petersburg, Florida); Erica Casper (St. Petersburg, Florida) |
ABSTRACT | A real-time reverse transcription-PCR, or NABSA, method (and associated primers) targeting the rbcL gene for the detection and quantitation of the Florida red tide organism, Karenia brevis. |
FILED | Tuesday, March 16, 2010 |
APPL NO | 12/724854 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/24.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 23, 2011.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2011/fedinvent-patents-20110823.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page