FedInvent™ Patents
Patent Details for Tuesday, September 06, 2011
This page was updated on Monday, March 27, 2023 at 02:03 AM GMT
Department of Defense (DOD)
| US 08011027 | Brookman |
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| ASSIGNEE(S) | Interspiro, Inc. (Pleasant Prairie, Wisconsin) |
| INVENTOR(S) | Michael J. Brookman (Branford, Connecticut) |
| ABSTRACT | A sealing mechanism for use in protective garments, such as hazard suits and the like, enables components of the protective garments, such as gas masks, hoses, respirators and the like to be removably attached to the garment material. The sealing mechanism includes a framing ring which may be attached to an object to be sealed to the garment material and a locking ring. The framing ring and the locking ring are adapted to engage each other in a snap fit type connection while trapping a portion of the garment material therebetween to thereby form an airtight seal between the object and the protective garment. |
| FILED | Wednesday, November 17, 2004 |
| APPL NO | 10/991782 |
| ART UNIT | 3765 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Apparel 02/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08011188 | Woltmann et al. |
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| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Ivan Elmer Woltmann (West Chester, Ohio); Sean Stacey Archer (Cincinnati, Ohio); Frank Gerald Bachman (Maineville, Ohio); Ralph Henry Winslow (Fairfield, Ohio) |
| ABSTRACT | A gas turbine engine augmentor includes an annular trapped vortex cavity pilot having a cavity forward wall, a cavity radially outer wall, and a cavity aft wall, an annular cavity therebetween, and cavity fuel injector tubes operably disposed through the outer wall into the cavity. Circumferentially spaced apart radial flameholders with integral spraybars and/or radial spraybars interdigitated with the radial flameholders radially inwardly into an exhaust flowpath of the augmentor just forward and upstream of the trapped vortex cavity pilot at a radially outer portion of a combustion zone of the exhaust flowpath. An annular trapped dual vortex cavity pilot version is operable for producing trapped dual counter-rotating inner and outer vortices of fuel and air mixtures. |
| FILED | Friday, August 31, 2007 |
| APPL NO | 11/848587 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/766 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08011239 | Chadwick et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David B. Chadwick (San Diego, California); Gunther H. Rosen (San Diego, California); G. Allen Burton (Ann Arbor, Michigan) |
| ABSTRACT | A system includes a plurality of chamber holders having openings therein, and an exposure chamber positioned in each chamber holder. Each exposure chamber includes a mesh portion and a top end cap. One exposure chamber contains a mesh bottom and one contains a closed bottom. Each chamber holder is positioned within an opening contained within a base portion. One exposure chamber may extend beyond the lower boundary of the base portion. A top portion may be secured to the base portion to contain the chamber holders. A pump, with connected supply hose, may be coupled to the top portion. The supply hose is routed through the chamber holders such that a supply hose opening is adjacent to each chamber holder. The system may include a water quality sensor and a passive sampling device coupled to the base portion. A deployment system may be connected to the top portion. |
| FILED | Tuesday, November 10, 2009 |
| APPL NO | 12/615919 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/170.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08011349 | Felton |
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| ASSIGNEE(S) | Delphi Technologies Holdings S.arl (Troy, Michigan) |
| INVENTOR(S) | George Nicholas Felton (Gillingham, United Kingdom) |
| ABSTRACT | A fuel injection system for an internal combustion engine comprises a plurality of pumps arranged to supply respective flows of pressurized fuel to a common accumulator volume that supplies the pressurized fuel in turn to a plurality of fuel injectors. An engine control unit controls the flow rate of pressurized fuel into the accumulator volume in response to engine load. The flow rate of pressurized fuel from at least one pump of the plurality is dependent upon engine speed; whereas at least one other pump of the plurality comprises a fuel output control responsive to the engine control unit enabling the flow rate of pressurized fuel from that pump to be varied independently of engine speed. In this way, the engine control unit controls the aggregate flow rate of pressurized fuel from the pumps into the accumulator volume, while controlling only one of the pumps. This reduces the cost of control apparatus and allows greater freedom of pump selection and flow circuit design. |
| FILED | Wednesday, November 26, 2008 |
| APPL NO | 12/315075 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/436 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08011424 | Murray |
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| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark M Murray (Annapolis, Maryland) |
| ABSTRACT | A convective heat transfer system for use with a fluid with particles, including a fluid channel having a wall and being capable of transferring the fluid, and a field emitter operable to emit a time-varying field into the fluid channel such that, when the fluid is in the channel, the time varying field affects a portion of the particles to change the rate of heat transfer between the channel and the fluid. The fluid can be a slurry with suspended field reactive particles. The system can include a plurality of field emitters located along the walls of the fluid channel, to vary the field and manipulate the distribution of the particles within the slurry, thereby changing the heat transfer characteristics of the system. The field can be an electric field or a magnetic field. The fluid channel can be disposed in a heat transfer system. |
| FILED | Friday, June 09, 2006 |
| APPL NO | 11/423310 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Heat exchange 165/276 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08011884 | Murray |
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| ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| INVENTOR(S) | Stephen E Murray (Port St. Lucie, Florida) |
| ABSTRACT | A small twin spool gas turbine engine with a forward end of the engine supported by bearings that are cooled by passing a cooling fluid such as cooling air bled off from the compressor with a liquid lubricant sprayed into the cooling air that is then passed through the bearing to prevent overheating. The cooling fluid is then discharged from the bearing cooling circuit out the front end of the engine through a number of discharge holes formed within the threaded nut that secures the fan blade assembly to the low speed rotor shaft. The threaded nut includes a plurality of slanted holes that slant outward from the rotational axis in the direction of fluid discharge. |
| FILED | Friday, August 01, 2008 |
| APPL NO | 12/184802 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/180 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012277 | Nicolich et al. |
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| ASSIGNEE(S) | Alliant Techsystems Inc. (Edina, Minnesota); Steven M. Nicolich (Wyckoff, New Jersey); Wendy A. Balas (Piscataway, New Jersey) |
| INVENTOR(S) | Steven M. Nicolich (Wyckoff, New Jersey); Alexander J. Paraskos (Ogden, Utah); Daniel W. Doll (Marriott Slaterville, Utah); Gary K. Lund (Malad, Idaho); Wendy A. Balas (Piscataway, New Jersey) |
| ABSTRACT | An ionic liquid is disclosed A precursor composition that comprises at least one ionic liquid and at least one energetic material is also disclosed, as is a method of synthesizing an ionic liquid and a method of desensitizing an explosive composition. |
| FILED | Friday, April 13, 2007 |
| APPL NO | 11/735105 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012278 | Russell et al. |
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| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alan J. Russell (Gibsonia, Pennsylvania); Sang B. Lee (Harrison City, Pennsylvania) |
| ABSTRACT | A method for joining nanotubes end-to-end, includes contacting the nanotubes with a joining fluid. The joining fluid has at least one property that is different from at least one property associated with ends of the nanotubes. In one embodiment, the method further includes contacting the nanotubes with a first, treating fluid and removing the bulk first fluid before the nanotubes are contacted with the joining fluid. The joining fluid is immiscible in the treating fluid to effect end-to-end joining of the nanotubes. |
| FILED | Friday, April 27, 2007 |
| APPL NO | 11/796492 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012326 | Weiller et al. |
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| ASSIGNEE(S) | The Regeants Of The Universtiy Of California (Oakland, California); The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Bruce H. Weiller (Santa Monica, California); Shabnam Virji (Yorba Linda, California); Richard B. Kaner (Pacific Palisades, California); Jiaxing Huang (Los Angeles, California) |
| ABSTRACT | Polymer nanofibers, such as polyaniline nanofibers, with uniform diameters less than 500 nm can be made in bulk quantities through a facile aqueous and organic interfacial polymerization method at ambient conditions. The nanofibers have lengths varying from 500 nm to 10 μm and form interconnected networks in a thin film. Thin film nanofiber sensors can be made of the polyaniline nanofibers having superior performance in both sensitivity and time response to a variety of gas vapors including, acids, bases, redox active vapors, alcohols and volatile organic chemicals. |
| FILED | Thursday, February 01, 2007 |
| APPL NO | 11/701218 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/431 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012374 | van Ooij et al. |
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| ASSIGNEE(S) | The University Of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | William J. van Ooij (Fairfield, Ohio); Hrishikesh Manian (Cincinnati, Ohio); Lin Yang (Cincinnati, Ohio); Hai Yang (Shanghai, China PRC) |
| ABSTRACT | The present invention provides for a slow-release inhibitor that is applied to a metal surface, such as by way of a paint or primer coating, for corrosion control of the metal. An exemplary embodiment of the slow-release corrosion inhibitor includes a water-soluble particle, or pigment, and an organic polymeric film that encapsulates the particle. This water-soluble particle may be either organic or inorganic and, preferably, is non-carcinogenic and non-toxic. An additional water-soluble particle having an encapsulating, organic polymeric film further may be provided along with a water-soluble, organic compound to form the corrosion inhibitor. The polymeric film(s) are of a desired hydrophobicity and permeability to permit, upon interaction of the particle(s) with water, controlled diffusion of particle ions therethrough. |
| FILED | Thursday, November 04, 2004 |
| APPL NO | 10/981017 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/389.540 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012382 | Kim et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Enoch Kim (Boston, Massachusetts); Younan Xia (St. Louis, Missouri); Milan Mrksich (Hinsdale, Illinois); Rebecca J. Jackman (Jamaica Plain, Massachusetts); Xiao-Mei Zhao (Pepper Pike, Ohio); Stephen P. Smith (Medford, Massachusetts); Christian Marzolin (Paris, France); Mara G. Prentiss (Belmont, Massachusetts); George M. Whitesides (Newtown, Massachusetts) |
| ABSTRACT | Chemically or biochemically active agents or other species are patterned on a substrate surface by providing a micromold having a contoured surface and forming, on a substrate surface, a chemically or biochemically active agent or fluid precursor of a structure. A chemically or biochemically active agent or fluid precursor also can be transferred from indentations in an applicator to a substrate surface. The substrate surface can be planar or non-planar. Fluid precursors of polymeric structures, inorganic ceramics and salts, and the like can be used to form patterned polymeric articles, inorganic salts and ceramics, reactive ion etch masks, etc. at the surface. The articles can be formed in a pattern including a portion having a lateral dimension of less than about 1 millimeter or smaller. The indentation pattern of the applicator can be used to transfer separate, distinct chemically or biochemically active agents or fluid precursors to separate, isolated regions of a substrate surface. Waveguide arrays, combinatorial chemical or biochemical libraris, etc. can be made. Differences in refractive index of waveguide and cladding can be created by subjecting the waveguide and cladding, made of indentical prepolymeric material, to different polymerization or cross-linking conditions. Interferometers are defined by coupling arrays of waveguides, where coupling can be controlled by altering the difference in refractive index between cladding and waveguide at any desired location of the array. Alteration and refractive index can be created photochemically, chemically, or the like. Sensors also are disclosed, including biochemical sensors. |
| FILED | Wednesday, March 04, 2009 |
| APPL NO | 12/398132 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/1.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012400 | Mirkin et al. |
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| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Xiaogang Liu (Evanston, Illinois); Shouwu Guo (Minneapolis, Minnesota) |
| ABSTRACT | Polymeric microstructures and nanostructures can be prepared with use of a tip to pattern a surface. A tip can be used to pattern a structure which can initiate polymerization. The structure can be then exposed to monomer to induce polymerization at the structure. Alternatively, a tip can be used to pattern a surface with a monomer in which the surface is treated with polymerization catalyst so that polymerization occurs at the patterning site. Ring-opening metathesis polymerization can be carried out with use of the tip to control the polymerization. The tip can be a sharp tip as used in for example an atomic force microscope tip. Norbornene types of monomers can be used. Biological macromolecules can be also prepared. |
| FILED | Friday, December 28, 2007 |
| APPL NO | 11/966764 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/494 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012493 | Fried et al. |
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| ASSIGNEE(S) | Seattle Biomedical Research Institute (Seattle, Washington); The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michal Fried (Seattle, Washington); Patrick E Duffy (Seattle, Washington); Susan Francis (Seattle, Washington); Jason P Wendler (Lincoln, Nebraska); Theonest K Mutabingwa (Muheza, Tanzania); Andrew Oleinikov (Mill Creek, Washington) |
| ABSTRACT | The invention provides isolated placental P. falciparum polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:1-4 and 6-24, and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the placental P. falciparum polypeptides of the invention, compositions comprising one or more placental P. falciparum polypeptides of the invention, methods for inducing an immune response against the placental P. falciparum polypeptides, and methods for treating and diagnosing placental malaria. |
| FILED | Tuesday, December 08, 2009 |
| APPL NO | 12/633474 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/272.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012534 | Ciaramitaro et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David A. Ciaramitaro (Ridgecrest, California); Brian A. Zentner (Ridgecrest, California); Andrew J. Lieux (Ridgecrest, California); Anna R. Merritt (Ridgecrest, California) |
| ABSTRACT | A process is provided for coating particulate materials with a thermoset polymeric coating that is less prone to creep or abrasion than a thermoplastic coating. The process provides for the coating of water-reactive and water-soluble materials which require a non-aqueous media for processing and also provides for the coating of particulate materials which must be processed in water. Also, all organics may be recovered, and there is no solvent contamination of water. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope of the claims. |
| FILED | Monday, June 15, 2009 |
| APPL NO | 12/459118 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Coating processes 427/212 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08012616 — Advanced apparatus for generating electrical power from aquatic sediment/water interfaces
| US 08012616 | Tender |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Leonard M. Tender (Bethesda, Maryland) |
| ABSTRACT | An improved benthic microbial fuel cell for generating energy at the interface of aquatic sediment and seawater includes an anode electrode embedded within the aquatic sediment, a cathode electrode positioned within the seawater and above the aquatic sediment, a rig for maintaining the relative positions of the anode and cathode electrodes, electrical leads extending from the anode and cathode electrodes to a load, wherein the anode electrode comprises a bottlebrush electrode residing within a permeable tube. The apparatus is easier to deploy than previously-described fuel cells, while being lighter, more durable, and generating greater power density. Also disclosed are methods of generating power from such an apparatus. |
| FILED | Wednesday, December 15, 2010 |
| APPL NO | 12/968547 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012633 | Gordon et al. |
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| ASSIGNEE(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | John Howard Gordon (Salt Lake City, Utah); Shekar Balagopal (Sandy, Utah); Sai Bhavaraju (West Jordan, Utah); John Joseph Watkins (West Jordan, Utah) |
| ABSTRACT | A metal-air battery is disclosed in one embodiment of the invention as including a cathode to reduce oxygen molecules and an alkali-metal-containing anode to oxidize the alkali metal (e.g., Li, Na, and K) contained therein to produce alkali-metal ions. An aqueous catholyte is placed in ionic communication with the cathode to store reaction products generated by reacting the alkali-metal ions with the oxygen containing anions. These reaction products are stored as solutes dissolved in the aqueous catholyte. An ion-selective membrane is interposed between the alkali-metal containing anode and the aqueous catholyte. The ion-selective membrane is designed to be conductive to the alkali-metal ions while being impermeable to the aqueous catholyte. |
| FILED | Friday, October 12, 2007 |
| APPL NO | 11/871824 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/405 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012699 | Ching |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Wei-Mei Ching (Bethesda, Maryland) |
| ABSTRACT | The invention relates to the construction of recombinant, immunodominant Rickettsia typhi proteins. The invention also relates to a method for the use of the recombinant proteins, either singly or in combination, in detection and diagnostic assays. The proteins can also be used in anti-Rickettsia typhi immunogenic formulations. |
| FILED | Monday, April 27, 2009 |
| APPL NO | 12/454038 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012739 | Schultz et al. |
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| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason W. Chin (San Diego, California); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (San Diego, California); Miro Pastrnak (San Diego, California); Stephen William Santoro (San Diego, California); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Friday, October 26, 2007 |
| APPL NO | 11/978154 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012794 | Ye |
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| ASSIGNEE(S) | Applied Materials, Inc. (Santa Clara, California) |
| INVENTOR(S) | Yan Ye (Saratoga, California) |
| ABSTRACT | A capping layer may be deposited over the active channel of a thin film transistor (TFT) in order to protect the active channel from contamination. The capping layer may affect the performance of the TFT. If the capping layer contains too much hydrogen, nitrogen, or oxygen, the threshold voltage, sub threshold slope, and mobility of the TFT may be negatively impacted. By controlling the ratio of the flow rates of the nitrogen, oxygen, and hydrogen containing gases, the performance of the TFT may be optimized. Additionally, the power density, capping layer deposition pressure, and the temperature may also be controlled to optimize the TFT performance. |
| FILED | Monday, June 29, 2009 |
| APPL NO | 12/493718 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012796 | Andry et al. |
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| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Paul S. Andry (Yorktown Heights, New York); John M. Cotte (New Fairfield, Connecticut); John U. Knickerbocker (Monroe, New York); Cornelia K. Tsang (Mohegan Lake, New York) |
| ABSTRACT | Apparatus and methods are provided for high density packaging of semiconductor chips using silicon space transformer chip level package structures, which allow high density chip interconnection and/or integration of multiple chips or chip stacks high I/O interconnection and heterogeneous chip or function integration. |
| FILED | Monday, August 10, 2009 |
| APPL NO | 12/538223 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/107 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012987 | Pitzer et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kevin K. Pitzer (Pasadena, Maryland); John P. Scovill (Walkersville, Maryland); Dennis E. Kyle (Gaithersburg, Maryland); Lucia Gerena (Silver Spring, Maryland) |
| ABSTRACT | Compounds, compositions and methods are provided for treating malaria parasites in vitro and in vivo by administering indolo [2,1-b]quinazoline-6,12-dione compounds of Formula I. wherein A, B, C, D, B, F, G and H are independently selected from carbon and nitrogen, or A and B or C and D can be taken together to be nitrogen or sulfur, with the proviso that not more than three of A, B, C, D, E, F, G and H are other than carbon; wherein R1 through R8 are independently selected from the group consisting of, but not limited to H, the halogens (F, Cl, Br, and I), alkyl groups, trifluoromethyl groups, methoxyl groups, the carboxy methyl or carboxy ethyl group (COOCH3 or COOCH2CH3), nitro, aryl, heteroaryl, cyano, amino, dialkylaminoalkyl, 1-(4-alkylpiperazinyl), and the pharmaceutically acceptable salts thereof; and wherein X is independently selected from the group consisting of any atom especially oxygen, or any side chain necessary to make the indolo[2,1-b]quinazoline-6,12-dione compound a “prodrug” as the term is understood by one of ordinary skill in the art of medicinal chemistry. In other words, a side chain having a structure where a carbon-nitrogen double bond bears substituents that make the prodrug more water soluble and bioavailable. |
| FILED | Tuesday, February 28, 2006 |
| APPL NO | 11/364425 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/257 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013629 | Dalrymple et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Allen Dalrymple (Columbia, Maryland); Erik Demaine (Cambridge, Massachusetts); Neil Gershenfeld (Somerville, Massachusetts); Forrest Green (Cambridge, Massachusetts); Ara Knaian (Newton, Massachusetts) |
| ABSTRACT | A family of reconfigurable asynchronous logic elements that interact with their nearest neighbors permits reconfigurable implementation of circuits that are asynchronous at the bit level, rather than at the level of functional blocks. These elements pass information by means of tokens. Each cell is self-timed, and cells that are configured as interconnect perform at propagation delay speeds, so no hardware non-local connections are needed. A reconfigurable asynchronous logic element comprises a set of edges for communication with at least one neighboring cell, each edge having an input for receiving tokens from neighboring cells and an output for transferring tokens to at least one neighboring cell, circuitry configured to perform a logic operation utilizing received tokens as inputs and to produce an output token reflecting the result of the logic operation, and circuitry. A reconfigurable lattice of asynchronous logic automata comprises a plurality of reconfigurable logic automata that compute by locally passing state tokens and are reconfigured by the directed shifting of programming instructions through neighboring logic elements. |
| FILED | Wednesday, September 16, 2009 |
| APPL NO | 12/561262 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Electronic digital logic circuitry 326/38 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013688 | White et al. |
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| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | George E. White (Marietta, Georgia); Madhavan Swaminathan (Marietta, Georgia); Venkatesh Sundaram (Norcross, Georgia); Sidharth Dalmia (Norcross, Georgia) |
| ABSTRACT | The present invention provides all organic fully-packaged miniature bandpass filters, baluns, diplexers, multiplexers, couplers and a combination of the above manufactured using liquid crystalline polymer (LCP) and other multilayer polymer based substrates. These devices are manufactured using one or more LCP layers having integrated passive components formed thereon to provide the density and performance necessary for multi-band wireless devices. In the designs involving multiple LCP layers, the LCP layers are separated by prepeg layers. In accordance with an aspect of the present invention, coplanar waveguide, hybrid stripline/coplanar waveguide and/or microstrip topologies are utilized to form the integrated passive components, and the devices can be mass produced on large area panels at least 18 inches by 12 inches with line widths smaller than 10 um. |
| FILED | Wednesday, August 11, 2010 |
| APPL NO | 12/854617 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013690 | Miyashiro |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | TeraSys Technologies LLC (Honolulu, Hawaii) |
| INVENTOR(S) | Kevin Miyashiro (Honolulu, Hawaii) |
| ABSTRACT | An electronically tuned, absorptive, low-loss notch filter with high RF power handling capability is obtained using a four-port quadrature hybrid coupler connected to a matched pair of band pass resonator devices and resistive terminations. The notch filter design uses series-only tuning elements for the band pass resonator devices to raise the RF power handling of the band pass resonators far above conventional techniques while also being tunable at high speeds. The notch filter architecture and method can be used for interference cancellation in a wide range of wireless technologies, such as cellular phone, wireless routers, hand-held radios, satellite communications, and any other environments where there are a number of wireless technologies in close signal proximity. |
| FILED | Wednesday, February 11, 2009 |
| APPL NO | 12/369256 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/176 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013792 | McCarthy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Daniel McCarthy (Manlius, New York); Dean Paschen (Lafayette, Colorado); Lary Eichel (Louisville, Colorado); Frank Pratt (Tipp City, Ohio) |
| ABSTRACT | Method and apparatus for minimizing antenna backside signal response and ambiguity in low frequency applications, particularly low frequency synthetic aperture radar (SAR). Various time delay elements are selectably switched into the signal path so as to cause a null to be placed in the antenna response pattern in the direction of undesired radar returns. The means for selectably switching may be dithered so as to introduce modulation onto the undesired radar return to aid in the discrimination and removal of the undesired radar return from the SAR image during post processing. |
| FILED | Thursday, August 06, 2009 |
| APPL NO | 12/462632 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014387 | Arimilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Ravi K. Arimilli (Austin, Texas); Ramakrishnan Rajamony (Austin, Texas) |
| ABSTRACT | A mechanism is provided for transmitting data from a first processor of a data processing system to a second processor of the data processing system. In one or more switches, a set of virtual channels is created, the one or more switches comprising, for each processor, a corresponding switch in the one or more switches. The data is transmitted from the first processor to the second processor through a path comprising a subset of processors of a set of processors in the data processing system. In each processor of the subset of processors, the data is stored in a virtual channel of a corresponding switch before transmitting the data to a next processor. The virtual channel of the corresponding switch in which the data is stored corresponds to a position of the processor in the path through which the data is transmitted. |
| FILED | Monday, August 27, 2007 |
| APPL NO | 11/845211 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/353 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014636 | Shubin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Oracle America (Redwood City, California) |
| INVENTOR(S) | Ivan Shubin (San Diego, California); Guoliang Li (San Diego, California); John E. Cunningham (San Diego, California); Ashok Krishnamoorthy (San Diego, California); Xuezhe Zheng (San Diego, California) |
| ABSTRACT | A phase modulation waveguide structure includes one of a semiconductor and a semiconductor-on-insulator substrate, a doped semiconductor layer formed over the one of a semiconductor and a semiconductor-on-insulator substrate, the doped semiconductor portion including a waveguide rib protruding from a surface thereof not in contact with the one of a semiconductor and a semiconductor-on-insulator substrate, and an electrical contact on top of the waveguide rib. The electrical contact is formed of a material with an optical refractive index close to that of a surrounding oxide layer that surrounds the waveguide rib and the electrical contact and lower than the optical refractive index of the doped semiconductor layer. During propagation of an optical mode within the waveguide structure, the electrical contact isolates the optical mode between the doped semiconductor layer and a metal electrode contact on top of the electrical contact. |
| FILED | Friday, February 20, 2009 |
| APPL NO | 12/389608 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014676 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alcatel Lucent (Paris, France) |
| INVENTOR(S) | Young-Kai Chen (Berkeley Heights, New Jersey); Sanjay Patel (New Providence, New Jersey); Mahmoud Rasras (Berkeley Heights, New Jersey); Kun-Yii Tu (Califon, New Jersey) |
| ABSTRACT | According to one embodiment, a microwave photonic band-stop (MPBS) filter uses an electrical input signal to drive an optical Mach-Zehnder modulator. A modulated optical carrier produced by the modulator is applied to an optical filter having at least two tunable spectral attenuation bands that are located substantially symmetrically on either side of the carrier frequency. The resulting filtered optical signal is applied to an optical-to-electrical (O/E) converter to produce an electrical output signal. |
| FILED | Friday, February 22, 2008 |
| APPL NO | 12/035677 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/85 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014745 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thinh Q. Ho (Anaheim, California); Stephen M. Hart (San Jose, California) |
| ABSTRACT | A compensation apparatus for an integrated communication system is disclosed. The integrated communication system can include a first communication device having a first transmitter antenna, and a second communication device having a second receiver antenna, wherein the second receiver antenna is in appreciable proximity of the first transmitter antenna such that the second receiver antenna picks up substantial electromagnetic interference from the first communication device. The compensation apparatus can include an isolation device having compensation circuitry coupling the first transmitter antenna and the second receiver antenna and configured to adaptively cancel the electromagnetic interference from the first communication device at the second receiver antenna. |
| FILED | Friday, February 20, 2009 |
| APPL NO | 12/389610 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Telecommunications 455/278.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014783 | Seidel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Powerwave Cognition, Inc. (Santa Ana, California) |
| INVENTOR(S) | Scott Y. Seidel (Fairfax, Virginia); Mohiuddin Ahmed (Moorpark, California) |
| ABSTRACT | Communicating between a plurality of nodes includes sensing spectrum activity on at least one channel; generating spectrum awareness data based at least in part on the sensed spectrum activity; determining at least one selected bearer based on the spectrum awareness data; negotiating among nodes to select at least one bearer based on various spectral use criteria. |
| FILED | Friday, November 10, 2006 |
| APPL NO | 11/595493 |
| ART UNIT | 2617 — Semiconductors/Memory |
| CURRENT CPC | Telecommunications 455/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014959 | Trepagnier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sparta, Inc. (Lake Forest, California) |
| INVENTOR(S) | Pierre C. Trepagnier (Medford, Massachusetts); Philip D. Henshaw (Carlisle, Massachusetts) |
| ABSTRACT | Methods and systems are disclosed for detection of agents such as pathogens or toxic substances and, in particular, to methods and systems for determining the most important background constituents to suppress in a sample, e.g., in a bulk aerosol sample, in order to reduce the probability of false alarms and improve the level of detection of potentially harmful airborne agents. |
| FILED | Wednesday, May 07, 2008 |
| APPL NO | 12/116673 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015125 | Regli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | William C. Regli (Philadelphia, Pennsylvania); Ali Shokoufandeh (New Hope, Pennsylvania); Dmitriy Bespalov (Philadelphia, Pennsylvania) |
| ABSTRACT | A scale-Space feature extraction technique is based on recursive decomposition of polyhedral surfaces into surface patches. The experimental results show that this technique can be used to perform matching based on local model structure. Scale-space techniques can be parameterized to generate decompositions that correspond to manufacturing, assembly or surface features relevant to mechanical design. One application of these techniques is to support matching and content-based retrieval of solid models. Scale-space technique can extract features that are invariant with respect to the global structure of the model as well as small perturbations that 3D laser scanning may introduce. A new distance function defined on triangles instead of points is introduced. This technique offers a new way to control the feature decomposition process, which results in extraction of features that are more meaningful from an engineering viewpoint. The technique is computationally practical for use in indexing large models. |
| FILED | Thursday, August 30, 2007 |
| APPL NO | 11/847942 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015133 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SAS Institute Inc. (Cary, North Carolina) |
| INVENTOR(S) | Lizhong Wu (San Diego, California); Terrance Gordon Barker (Cardiff by the Sea, California); Vijay S. Desai (San Diego, California) |
| ABSTRACT | Computer-implemented systems and methods for analyzing activities associated with accesses of a computer network. A computer-implemented method can be configured to receive data related to the activities associated with the accesses of a computer network. The network activities data are segmented into a plurality of network activities segments. For each of the network activities segments, an anomaly detection predictive model is generated. The generated predictive models are for use in analyzing the activities associated with the computer network. |
| FILED | Thursday, September 06, 2007 |
| APPL NO | 11/850842 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015211 | Marceau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| INVENTOR(S) | Carla Marceau (Ithaca, New York); Matthew A. Stillerman (Ithaca, New York) |
| ABSTRACT | A peer-to-peer (P2P) networking system is disclosed that provides a large, persistent object repository with the ability to easily scale to significant size. Data security is provided using a distributed object data access mechanism to grant access to data objects to authorized users. Data objects stored within the object repository are provided a plurality of security options including plain text data, objects, encrypted data objects, and secure, secret sharing data objects. A data object query processing component permits users to locate requested information within the P2P networking system. |
| FILED | Friday, October 01, 2004 |
| APPL NO | 10/957235 |
| ART UNIT | 2162 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/802 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015379 | Arimilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas) |
| ABSTRACT | A wake-and-go mechanism is configured to issue a look-ahead load command on a system bus to read a data value from a target address and perform a comparison operation to determine whether the data value at the target address indicates that an event for which a thread is waiting has occurred. In response to the comparison resulting in a determination that the event has not occurred, the wake-and-go engine populates the wake-and-go storage array with the target address. In response to the comparison resulting in a determination that the event has occurred, the wake-and-go engine issues a load command on the system bus to read the data value from the target address with data exclusivity and determines whether the wake-and-go engine obtains a lock for the target address. Responsive to obtaining the lock for the target address, the wake-and-go engine holds the lock for the thread. |
| FILED | Friday, February 01, 2008 |
| APPL NO | 12/024250 |
| ART UNIT | 2189 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/163 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015380 | Arimilli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ravi K. Arimilli (Austin, Texas); Robert S. Blackmore (Poughkeepsie, New York); Chulho Kim (Poughkeepsie, New York); Balaram Sinharoy (Poughkeepsie, New York); Hanhong Xue (Poughkeepsie, New York) |
| ABSTRACT | A data processing system has an asynchronous memory mover, which includes multiple sets of registers for storing addressing and control parameters utilized to generate one or more asynchronous memory move (AMM) operations. The memory mover detects a receipt of a first set of parameters in a first set of registers from the processor. The processor forwards the parameters after the processor initiates a data move in virtual address space, utilizing a source effective address and a destination effective address. The memory mover responds to receiving the first set of parameters by generating and launching a first asynchronous memory move (AMM) operation. When the memory mover receives a second set of parameters in a second set of registers before the first AMM operation completes, the memory mover generates and launches a second AMM operation concurrently with the first AMM operation if no address conflicts exist. |
| FILED | Friday, February 01, 2008 |
| APPL NO | 12/024690 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/165 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015601 | McDermott |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John P McDermott (Annandale, Virginia) |
| ABSTRACT | A controller for an event-based statistical covert channel includes a data receiver; a data transmitter; and a channel controller that includes a fixed distribution randomized event buffer construction processor (FDREBCP) and a fixed distribution randomized event buffer (FDREB). The FDREBCP holds event distribution data that define one or more fixed distributions that the FDREBCP employs to fill the FDREB, whereby the event distribution data is stored during the occurrence of the event, subsequently removed from the FDREB and reordered, and a dummy event distribution data created to prevent an unauthorized outsider modulating the timing of events by alternatively causing and not causing the event. |
| FILED | Friday, July 13, 2007 |
| APPL NO | 11/777932 |
| ART UNIT | 2453 — Computer Networks |
| CURRENT CPC | Information security 726/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015605 | Yegneswaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Vinod T. Yegneswaran (Foster City, California); Paul R. Barford (Madison, Wisconsin); David J. Plonka (Madison, Wisconsin) |
| ABSTRACT | A monitor of malicious network traffic attaches to unused addresses and monitors communications with an active responder that has constrained-state awareness to be highly scalable. In a preferred embodiment, the active responder provides a response based only on the previous statement from the malicious source, which in most cases is sufficient to promote additional communication with the malicious source, presenting a complete record of the transaction for analysis and possible signature extraction. |
| FILED | Monday, August 29, 2005 |
| APPL NO | 11/214399 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Information security 726/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US H2262 | Nechitailo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas V. Nechitailo (King George, Virginia) |
| ABSTRACT | A penetrator instrument disposable in a projectile is provided for penetrating a target. The instrument includes a substantially cylindrical shell and a tip element. The shell includes a cavity at a fore end. The surface has an interior annular surface. The tip element is disposable into the cavity. The element has an exterior annular surface. The shell radially compresses the tip element along respective the interior and exterior annular surfaces that adjoin each other. The shell can optionally include an aft bore for mass balancing or containment of auxiliary materials. The element can be a ceramic or composed of reactive materials. |
| FILED | Friday, September 11, 2009 |
| APPL NO | 12/291047 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Ammunition and explosives 12/517 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US H2263 | Metzger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | William W. Metzger (Princeton Junction, New Jersey); Robert F. Schmicker (Island Heights, New Jersey) |
| ABSTRACT | A thermal control system for a space body uses an active control means to prevent laser beam radiation damage to a heat radiator. A conventional louver and louver actuator are coupled to an active overdrive actuator that closes the louver when hostile laser radiation is present. An extended bimetallic coil spring with a heater therein rotates opposite to the louver actuator in an increasing temperature environment. A cam of the overdrive actuator engages a louver arm when hostile laser radiation is present, otherwise, the louver can move freely within the cam. |
| FILED | Wednesday, October 03, 1984 |
| APPL NO | 06/700989 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeronautics and astronautics 244/171.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US H2264 | Gladden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Maureen J. Gladden (Beaverdam, Virginia); Jennifer E. O'Leary (Stafford, Virginia); Colleen A. Johnson (Fredericksburg, Virginia); Donald J. Lemoine (Fredericksburg, Virginia); Frank J. Petranka (Fredericksburg, Virginia) |
| ABSTRACT | A method and a system for driving a computer interface for a user is provided. The system includes an interface client having a computer platform, a test driver having software on the computer platform; a window displayed to the interface client, the window providing an interface between the computer platform and the user; and a command file that provides an instruction to the computer interface for executing by the driver software, such that the instruction mimics a user input. The method includes providing instructions through a command file having an instruction for execution on the computer interface, providing driver software to the computer interface, and executing the instruction on the computer interface using the driver software, such that the instruction mimics a user input. |
| FILED | Wednesday, May 16, 2007 |
| APPL NO | 11/805266 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 08012160 | Jensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Joel F. Jensen (Redwood City, California); Philip S. Green (Palo Alto, California) |
| ABSTRACT | The invention is directed to a system and method for releasably holding a surgical instrument (14), such as an endoscopic instrument configured for delivery through a small percutaneous penetration in a patient. The instrument comprises an elongate shaft (100) with a pair of mounting pins (116) laterally extending from the shaft between its proximal and distal ends. An instrument holder comprises a support having a central bore (202) and an axially extending slot (204) for receiving the instrument shaft and the mounting pins. A pair of locking slots (206) are cut into the support transversely to and in communication with the axial slot so that the mounting pins can be rotated within the locking slots. The instrument support further includes a latch assembly for automatically locking the mounting pins within the locking slots to releasably couple the instrument to the instrument holder. With this twist-lock motion, the surgeon can rapidly engage and disengage various instruments from the holder during a surgical procedure, such as open surgery, laparoscopy or thoracoscopy. |
| FILED | Monday, September 18, 2006 |
| APPL NO | 11/522576 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 66/130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012349 | Bowers |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Orbital Biosciences, LLC (Topsfield, Massachusetts) |
| INVENTOR(S) | William F. Bowers (Topsfield, Massachusetts) |
| ABSTRACT | Methods and devices are provided for preparing and separating biological analytes. In one embodiment, one or more filtration devices or filter plate wells can be formed by clamping a filter sheet between first and second plates having at least one connecting cavity. First and second moveable core pins positioned on opposed sides of the sheet can be moved to remove portions of the sheet. A molten plastic can be injected to fill the volume between the cores and cavities and to form a liquid-impermeable sleeve wall or walls, each being separately sealed at the bottom to the perimeter of the sheet portion, each having liquid permeable regions of said removed and sealed sheet portion, and each remaining open at the top. Various exemplary configurations for filtration devices or filter plate wells are also disclosed. |
| FILED | Saturday, November 10, 2007 |
| APPL NO | 11/938257 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012466 | Morita et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Craig T. Morita (Iowa City, Iowa); Bradley D. Jones (Iowa City, Iowa) |
| ABSTRACT | Disclosed are compositions, kits, and methods for activating, expanding, or stimulating γδ T cells that include recombinant attenuated microbes. The compositions may include pharmaceutical compositions that are used as γδ T cell stimulating immunogenic compositions. |
| FILED | Friday, January 30, 2009 |
| APPL NO | 12/362968 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012476 | Dall'Acqua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | MedImmune, LLC (Gaithersburg, Maryland); Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | William Dall'Acqua (Gaithersburg, Maryland); Leslie S. Johnson (Germantown, Maryland); Elizabeth Sally Ward (Dallas, Texas) |
| ABSTRACT | The present invention provides molecules, including IgGs, non-IgG immunoglobulins, proteins and non-protein agents, that have increased in vivo half-lives due to the presence of an IgG constant domain, or a portion thereof that binds the FcRn, having one or more amino acid modifications that increase the affinity of the constant domain or fragment for FcRn. Such proteins and molecules with increased half-lives have the advantage that smaller amounts and or less frequent dosing is required in the therapeutic, prophylactic or diagnostic use of such molecules. |
| FILED | Thursday, January 21, 2010 |
| APPL NO | 12/691433 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012484 | Linden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Joel M. Linden (La Jolla, California); Courtney M. Lappas (Mclean, Virginia); Victor H. Engelhard (Crozet, Virginia) |
| ABSTRACT | The present invention relates to a method for treating recurrent tumor metastases following liver resection that includes administration of an effective amount of an agonist of A2A adenosine receptors (ARs). |
| FILED | Tuesday, March 25, 2008 |
| APPL NO | 12/054643 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/152.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012490 | Palese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mount Sinai School of Medicine (New York, New York); The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Peter Palese (Leonia, New Jersey); Adolfo Garcia-Sastre (New York, New York); Nicholas P. Restifo (Washington, District of Columbia) |
| ABSTRACT | The present invention relates to the engineering of recombinant influenza viruses that express tumor-associated antigens. Expression of tumor-associated antigens by these viruses can be achieved by engineering specific epitopes into influenza virus proteins, or by engineering viral genes that encode a viral protein and the specific antigen as independent polypeptides. Tumor-bearing patients can be immunized with the recombinant influenza viruses alone, or in combination with another treatment, to induce an immune response that leads to tumor reduction. The recombinant viruses can also be used to vaccinate high risk tumor-free patients to prevent tumor formation in vivo. |
| FILED | Tuesday, September 22, 2009 |
| APPL NO | 12/564702 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/199.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012493 | Fried et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Seattle Biomedical Research Institute (Seattle, Washington); The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michal Fried (Seattle, Washington); Patrick E Duffy (Seattle, Washington); Susan Francis (Seattle, Washington); Jason P Wendler (Lincoln, Nebraska); Theonest K Mutabingwa (Muheza, Tanzania); Andrew Oleinikov (Mill Creek, Washington) |
| ABSTRACT | The invention provides isolated placental P. falciparum polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:1-4 and 6-24, and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the placental P. falciparum polypeptides of the invention, compositions comprising one or more placental P. falciparum polypeptides of the invention, methods for inducing an immune response against the placental P. falciparum polypeptides, and methods for treating and diagnosing placental malaria. |
| FILED | Tuesday, December 08, 2009 |
| APPL NO | 12/633474 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/272.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012678 | Pyeon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Dohun Pyeon (Centennial, Colorado); Paul F. Lambert (Madison, Wisconsin); Michael A. Newton (Madison, Wisconsin); Paul G. Ahlquist (Madison, Wisconsin) |
| ABSTRACT | Cervical cancer cells and HPV+ head and neck cancer cells express three testis-specific genes not normally expressed in somatic cells: testicular cell adhesion molecule 1 (TCAM1), synaptonemal complex protein 2 (SYCP2) and stromal antigen 3 (STAG3). Among the three markers, TCAM1 and SYCP2 are early detection markers. Various methods for identifying a human or non-human animal as a candidate for further examination for cervical cancer, preneoplastic lesion for cervical cancer, head and neck cancer, or preneoplastic lesion for head and neck cancer are disclosed. Methods of detecting said cancers and preneoplastic lesions, methods of screening for drugs for treating said cancers and preneoplastic lesions, methods for monitoring the effectiveness of a treatment for said cancers, and methods of treating said cancers are also disclosed. Further disclosed are kits that can be used to practice the above methods. |
| FILED | Thursday, July 24, 2008 |
| APPL NO | 12/220465 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012683 | Allikmets et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); The Trustees of Columbia University in the City of New York (New York, New York); United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Rando L. Allikmets (Cornwall on Hudson, New York); Gregory S. Hageman (Coralville, Iowa); Michael C. Dean (Frederick, Maryland); Albert M. Gold (Frederick, Maryland) |
| ABSTRACT | Methods for identifying a subject at risk for developing AMD are disclosed, as are kits which can be used to practice the methods. The methods include identifying specific protective or risk polymorphisms or genotypes from the subject's genetic material, including polymorphisms in the BF, C2 and/or CFH genes. Microarrays and kits for use in these methods are also provided. |
| FILED | Tuesday, February 13, 2007 |
| APPL NO | 11/706074 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012695 | Kufe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Donald W. Kufe (Wellesley, Massachusetts) |
| ABSTRACT | This invention relates to regulation of cell signaling, cell growth, and more particularly to the regulation of cancer or inflammatory cell growth and/or activation. The invention provides methods of, and compositions useful for, inhibiting interactions between MUC1 and a kruppel-like factor (KLF), method of inhibiting interactions between a KLF protein and the p53 promoter, methods of inhibiting the interaction between MUC1 and the p53 promoter, methods of increasing p53 activity, and methods of increasing histone acetylation. The invention also provides screening methods for identifying compounds that inhibit the aforementioned interactions. Pharmaceutical compositions containing the identified compounds can be useful in treating cancers and inflammatory conditions. |
| FILED | Thursday, February 14, 2008 |
| APPL NO | 12/031316 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012702 | Jorgensen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Erik M. Jorgensen (Salt Lake City, Utah); Asim A. Beg (Ann Arbor, Michigan); Paola Nix (Salt Lake City, Utah) |
| ABSTRACT | The invention relates to an isolated or recombinant Na+/H+ exchanger comprising an isolated or recombinant Na+/H+ exchanger, particularly to the PBO-4 Na+/H+ exchanger. Also disclosed is an isolated or recombinant protein component of an H+-gated channel which can be affected by extracellular Ca2+ concentration. In particular, the invention relates to PBO-5 and/or PBO-8 and/or a H+-gated channel composed of PBO-5 and PBO-8. The invention relates to compounds isolated from a vertebrate organism, wherein said compounds comprise at least a part of a H+-gated channel or Na+/H+ exchanger. The invention also relates to a method for identifying a component of a H+-gated channel in a vertebrate organism. |
| FILED | Friday, October 15, 2010 |
| APPL NO | 12/905647 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012711 | Oethinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Margret Oethinger (Bad Oeynhausen, Germany); Stuart B. Levy (Boston, Massachusetts) |
| ABSTRACT | The instant methods and compositions represent an advance in controlling drug resistance in microbes. AcrAB-like efflux pumps have been found to control resistance to drugs, even in highly resistant microbes. Accordingly, methods of treating infection, methods of screening for inhibitors of AcrAB-like efflux pumps, and methods of enhancing antimicrobial activity of drugs are provided. Pharmaceutical composition comprising an inhibitor of an AcrAB-like efflux pump and an antimicrobial agent are also provided. |
| FILED | Monday, June 01, 2009 |
| APPL NO | 12/476053 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/32 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012718 | Ruano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Genomas, Inc. (Hartford, Connecticut) |
| INVENTOR(S) | Gualberto Ruano (Milford, Connecticut); Andreas Windemuth (South Glastonbury, Connecticut); John W. Goethe (Avon, Connecticut) |
| ABSTRACT | The invention is generally directed to a physiogenomic method for predicting diabetes and metabolic syndromes induced by psychotropic drugs. In one embodiment, the invention relates to the use of genetic variants of marker genes to predict the likelihood that an individual will experience undesirable metabolic side effects as a result of the use of a drug including, but not limited to, psychotropic drugs. The invention also relates to methods predicting the likelihood of diabetes and metabolic syndromes induced by the use of drugs with undesirable metabolic side effects. |
| FILED | Friday, March 30, 2007 |
| APPL NO | 11/694247 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012739 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason W. Chin (San Diego, California); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (San Diego, California); Miro Pastrnak (San Diego, California); Stephen William Santoro (San Diego, California); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Friday, October 26, 2007 |
| APPL NO | 11/978154 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012751 | Thomson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James A. Thomson (Madison, Wisconsin); Thomas P. Zwaka (Pearland, Texas) |
| ABSTRACT | The invention relates to a method to induce primate embryonic stem cells to differentiate into a relatively homogenous population of mesendoderm cells by treatment with caspase-like inhibitors. Also described is a population of mesendoderm cells obtained therefrom. The embryonic stem cell derived mesendoderm cells have the general morphological and cell surface marker characteristics of mesendoderm cells. |
| FILED | Friday, March 31, 2006 |
| APPL NO | 11/395657 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012756 | Pourmand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Nader Pourmand (Santa Cruz, California); Miloslav Karhanek (Santa Cruz, California); Ronald W. Davis (Palo Alto, California) |
| ABSTRACT | Methods and apparatus for direct detection of chemical reactions are provided. In a preferred embodiment, electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The target molecule is preferably DNA. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. The initial enzyme attachment to the DNA molecule can be detected prior to polymerization, with electrode capacitance measurement using the same voltage-clamp amplifier. This technique and device may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits. |
| FILED | Wednesday, June 23, 2010 |
| APPL NO | 12/821809 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012901 | Ortiz-Marciales et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Margarita Ortiz-Marciales (Humacao, Puerto Rico); Kun Huang (Corvallis, Oregon); Viatcheslav Stepanenko (Humacao, Puerto Rico); Melvin De Jesus (Humacao, Puerto Rico); Wildeliz Correa (Humacao, Puerto Rico) |
| ABSTRACT | A practical and efficient procedure for the enantioselective synthesis of mexiletine analogues using 10% of a novel spiroborate ester as chirality transfer agent is presented. A variety of mexiletine analogues were prepared with excellent enantioselectivities (91-97% ee) in good yield from readily available starting materials. The developed methodology was also successfully applied for the synthesis of novel β-amino ethers containing thiophenyl and pyridyl fragments. |
| FILED | Wednesday, April 15, 2009 |
| APPL NO | 12/386356 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012928 | Bluth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Albany, New York) |
| INVENTOR(S) | Martin H. Bluth (Southfield, Michigan); Michael Zenilman (Lawrence, New York) |
| ABSTRACT | A method of treating pancreatitis is provided, including the steps of: providing a mammal having pancreatitis; and administering a therapeutically effective amount of a truncated N-terminal PAP2; and making of an antibody specifically directed to detect PAP2. |
| FILED | Friday, December 18, 2009 |
| APPL NO | 12/642263 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012936 | Sigurdsson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Einar Sigurdsson (New York, New York); Ayodeji Asuni (New York, New York) |
| ABSTRACT | The present invention relates to methods of treating and preventing Alzheimer's Disease or other tauopathies in a subject by administering a tau protein, its immunogenic epitopes, or antibodies recognizing the tau protein or its immunogenic epitopes under conditions effective to treat or prevent Alzheimer's Disease of other tauopathies. Also disclosed are methods of promoting clearance of aggregates from the brain of the subject and of slowing progression of tangle-related behavioral phenotype in a subject. |
| FILED | Thursday, March 29, 2007 |
| APPL NO | 11/693375 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012943 | Duffield et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Optimer Pharmaceuticals, Inc. (San Diego, California) |
| INVENTOR(S) | Jonathan Duffield (San Diego, California); Chan-Kou Hwang (San Diego, California); Yoshitaka Ichikawa (San Diego, California); Youe-Kong Shue (Calsbad, California) |
| ABSTRACT | Described herein are novel macrolides, the preparation of novel macrolides, the use of novel macrolides for preventing, treating, or ameliorating various conditions, and the use of novel macrolides as antibacterial agents. |
| FILED | Monday, April 27, 2009 |
| APPL NO | 12/430736 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012945 | Hallahan et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Dennis E. Hallahan (Nashville, Tennessee); Raymond Mernaugh (Nashville, Tennessee) |
| ABSTRACT | A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor. |
| FILED | Monday, December 10, 2007 |
| APPL NO | 11/953780 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012947 | Tomic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Hospital for Special Surgery (New York, New York) |
| INVENTOR(S) | Marjana Tomic (Hillsdale, New Jersey); Carl Peter Blobel (Eastchester, New York); Asheesh Harsha (New York, New York) |
| ABSTRACT | Provided herein are compositions and methods that inhibit expression of Adam12 gene products, such as ADAM12 mRNA and/or ADAM12 polypeptides, as a therapeutic approach for the treatment of, or promotion of healing of, wounds. |
| FILED | Wednesday, March 12, 2008 |
| APPL NO | 12/047106 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012948 | Kruse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Promising Future, LLC (Hagatna, Guam) |
| INVENTOR(S) | Carol Kruse (San Diego, California); Richard Tritz (San Diego, California) |
| ABSTRACT | Provided herein are methods and compositions for killing tumor cells. In certain embodiments, compositions can promote apoptosis by down-regulating FAPP2 and PATZ1 products. |
| FILED | Wednesday, October 14, 2009 |
| APPL NO | 12/579259 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012949 | Oldfield et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Eric Oldfield (Champaign, Illinois); Yonghui Zhang (Urbana, Illinois); Fenglin Yin (Naperville, Illinois) |
| ABSTRACT | The disclosure provides, inter alia, novel bisphosphonate compounds and methods of making and using such compounds. In certain embodiments, compounds of the invention include bisphosphonates that are capable of selectively inhibiting one or more of farnesyl diphosphate synthase (FPPS), geranylgeranyl diphosphate synthase (GGPPS), and decaprenyl pyrophosphate synthase (DPPS). In preferred embodiments, compounds of the invention are capable of selectively inhibiting two or more of FPPS, GGPPS, and DPPS. In embodiments, compounds and methods of the invention demonstrate superior activity levels, such as in the anti-cancer context, immunostimulation context, and other contexts, which in several cases exceed the activity levels of previous generation bisphosphonate drugs by orders of magnitude. In embodiments, the invention provides compounds and methods in connection with research and therapeutic applications, e.g., for tumor or cancer cell growth inhibition, activation of gammadelta T cells, inhibition of certain enzymes related to the mevalonate metabolic pathway, bone resorption diseases, cancer, immune disorders, immunotherapy, and infectious diseases. |
| FILED | Friday, April 11, 2008 |
| APPL NO | 12/101484 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013006 | Karp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | PTC Therapeutics, Inc. (South Plainfield, New Jersey) |
| INVENTOR(S) | Gary Mitchell Karp (Princeton Junction, New Jersey); Peter Seongwoo Hwang (Edison, New Jersey); James Takasugi (Lawrenceville, New Jersey); Hongyu Ren (Dayton, New Jersey); Richard Gerald Wilde (Somerville, New Jersey); Anthony Turpoff (Edison, New Jersey); Alexander Arefolov (Piscataway, New Jersey); Guangming Chen (Bridgewater, New Jersey); Jeffrey Allen Campbell (Bethlehem, Pennsylvania); Christine Espiritu (Highland Park, New Jersey); Concetta Freund (Staten Island, New York); Zhengxian Gu (Princeton, New Jersey); Takashi Komatsu (Silver Spring, Maryland) |
| ABSTRACT | In accordance with the present invention, compounds that inhibit viral replication, preferably Hepatitis C Virus (HCV) replication, have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the treatment or prevention of a viral infection are provided. In another aspect of the invention, compounds useful in the treatment or prevention of HCV infection are provided. |
| FILED | Thursday, July 14, 2005 |
| APPL NO | 11/180961 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/415 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013014 | Powers et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | James C. Powers (Atlanta, Georgia); Jonathan D. Glass (Atlanta, Georgia) |
| ABSTRACT | Methods for treatment and/or prevention of nerve degeneration in mammals using aza-peptide epoxide caspase inhibitors are provided. Aspects of the present disclosure include aza-peptide epoxide compositions to treat or prevent diseases, for example stroke, Alzheimer's disease, Parkinson's disease, multiple sclerosis, neuropathies, Huntington's disease, dentatorubropallidoluysian atrophy, spinocerebellar atrophies, spinal bulbar muscular atrophy, diabetes, amyotrophic lateral sclerosis and other motor neuron diseases. The disclosed methods can be used in combination with calpain inhibitors to treat disease or pathological conditions related to the activity of caspases and calpain associated with a specific disease or condition. Such treatable conditions include stroke, Alzheimer's disease, Parkinson's disease, multiple sclerosis, neuropathies, Huntington's disease, dentatorubropallidoluysian atrophy, spinocerebellar atrophies, spinal bulbar muscular atrophy, nerve degeneration associated with diabetes, amyotrophic lateral sclerosis and other motor neuron diseases, nerve degeneration secondary to primary demyelinating disorders, among others. |
| FILED | Tuesday, January 24, 2006 |
| APPL NO | 11/338147 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/475 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013015 | Harran et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Patrcik G. Harran (Los Angeles, California); Michael S. Brown (Dallas, Texas); Joseph L. Goldstein (Dallas, Texas); Jing Yang (Dallas, Texas); Tong-Jin Zhao (Dallas, Texas) |
| ABSTRACT | Ghrelin O-acyltransferase (GOAT) is inhibited with designed small molecules. Methods comprise contacting the GOAT with an inhibitor and detecting a resultant inhibition. |
| FILED | Thursday, October 01, 2009 |
| APPL NO | 12/571538 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013120 | Du Clos et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Terry W. Du Clos (Albuquerque, New Mexico); Carolyn Mold (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to the use of C-reactive protein, its mutants, metabolites and polypeptides and related compounds thereof for the treatment of various disease states and conditions associated with systemic lupus erythematosus (SLE), including lupus of the skin (discoid), systemic lupus of the joints, lungs and kidneys, hematological conditions including hemolytic anemia and low lymphocyte counts, lymphadenopathy and CNS effects including memory loss, seizures and psychosis, among numerous others as otherwise disclosed herein, hi another aspect of the invention, the reduction in the likelihood that a patient who is at risk for an outbreak of a disease state or condition with systemic lupus erythematosus will have an outbreak is an additional aspect of the present invention. |
| FILED | Thursday, October 26, 2006 |
| APPL NO | 12/083055 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013127 | Wang |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Creighton University (Omaha, Nebraska) |
| INVENTOR(S) | Zhao Yi Wang (Bellevue, Nebraska) |
| ABSTRACT | The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-α36 activity. The invention further provides methods for identifying agents that bind to such polypeptides, methods for detecting such polypeptides, and methods for altering the activity of such polypeptides. Also provided are antibodies that specifically bind to an amino acid sequence depicted at SEQ ID NO:1, or an immunogenic fragment thereof, and methods for making and using such antibodies. |
| FILED | Monday, June 28, 2010 |
| APPL NO | 12/825057 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013142 | Sampath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ibis Biosciences, Inc. (Carlsbad, California) |
| INVENTOR(S) | Rangarajan Sampath (San Diego, California); Thomas A. Hall (Oceanside, California); David J. Ecker (Encinitas, California); Lawrence Blyn (Mission Viejo, California) |
| ABSTRACT | The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis. |
| FILED | Tuesday, March 13, 2007 |
| APPL NO | 11/685610 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013149 | Lindsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Jonathan S. Lindsey (Raleigh, North Carolina); Masahiko Taniguchi (Raleigh, North Carolina); Arumugham Balakumar (Raleigh, North Carolina); Dazhong Fan (Raleigh, North Carolina) |
| ABSTRACT | A method of making a porphyrin (I) is carried out by condensing (i) a bis(imino)dipyrromethane of Formula II: with (ii) a dipyrromethaneto produce a reaction product; then (b) optionally oxidizing said reaction product with an oxidizing agent; and then (c) optionally demetallating said reaction product to produce the porphyrin. Methods of making compounds of Formula II are also described. |
| FILED | Tuesday, June 30, 2009 |
| APPL NO | 12/494711 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013837 | Schroeder |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Ernest Schroeder (Helotes, Texas) |
| ABSTRACT | The apparatus and method help physically-disabled persons perform point-and-click activities or input text or control characters, which typically require the user to simultaneously control two independent dimensions to select options presented on a computer display. Computer users operate a control in a single dimension (i.e., two directions—first embodiment) or in just one direction (second embodiment). Different input strategies allow a person using the one- or two-directional control method to emulate pointer functions and input characters or character strings. An embodiment augments antagonistic muscle groups for persons exhibiting adequate control in one direction but not the other. An additional embodiment uses available two-dimensional pointers but restricts their operation to one dimension. The output of existing sensors is converted to a form that can be input directly to a computer to be used with a one-dimensional control strategy. |
| FILED | Tuesday, October 11, 2005 |
| APPL NO | 11/248944 |
| ART UNIT | 2629 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013853 | Douglas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Bill Douglas (Falson Heights, Minnesota); Ralph DeLong (New Brighton, Minnesota) |
| ABSTRACT | Systems and methods read clinical data records to create and three-dimensional images representing a virtual dental patient. The images can be used to assess the current dental health of a patient. In particular the systems and methods create accurate, three-dimensional virtual renditions of dental patients, compare the virtual renditions with other virtual renditions, and create computer databases of the renditions from which population statistics are calculated for parameters measured on the renditions. By comparing a particular patient rendition to the population statistics a report is produced that aids in the diagnosis of the patient's current dental health. |
| FILED | Thursday, March 06, 2003 |
| APPL NO | 10/385169 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014494 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Cedric X. Yu (Clarksville, Maryland); Shuang Luan (Albuquerque, New Mexico); Danny Z. Chen (Granger, Indiana); Matthew A. Earl (Crownsville, Maryland); Chao Wang (Columbia, Maryland) |
| ABSTRACT | Provided herein are methods and systems for designing a radiation treatment for a subject using single arc dose painting. The methods and systems comprise an algorithm or a computer-readable product having the same, to plan the radiation treatment. The algorithm converts pairs of multiple leaf collimation (MLC) leaves to sets of leaf aperture sequences that form a shortest path single arc thereof where the pairs of MLC leaves each aligned to an intensity profile of densely-spaced radiation beams, and connects each single arc of leaf apertures to form a final treatment single arc. Also provided is a method for irradiating a tumor in a subject using single arc dose painting. |
| FILED | Tuesday, October 20, 2009 |
| APPL NO | 12/589205 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014569 | Durkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anthony J. Durkin (Irvine, California); David Cuccia (Costa Mesa, California); Frederic Bevilacqua (Paris, France); Bruce J. Tromberg (Irvine, California) |
| ABSTRACT | A method and an apparatus for noninvasively and quantitatively determining spatially resolved absorption and reduced scattering coefficients over a wide field-of-view of a food object, including fruit or produce, uses spatial-frequency-domain imaging (SFDI). A single modulated imaging platform is employed. It includes a broadband light source, a digital micromirror optically coupled to the light source to control a modulated light pattern directed onto the food object at a plurality of selected spatial frequencies, a multispectral camera for taking a spectral image of a reflected modulated light pattern from the food object, a spectrally variable filter optically coupled between the food object and the multispectral camera to select a discrete number of wavelengths for image capture, and a computer coupled to the digital micromirror, camera and variable filter to enable acquisition of the reflected modulated light pattern at the selected spatial frequencies. |
| FILED | Monday, October 29, 2007 |
| APPL NO | 11/927396 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014583 | Zahniser |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cytyc Corporation (Marlborough, Massachusetts) |
| INVENTOR(S) | Michael Zahniser (Cambridge, Massachusetts) |
| ABSTRACT | A method for determining the quality of focus of a digital image of a biological specimen includes obtaining a digital image of a specimen using a specimen imaging apparatus. A measure of image texture is calculated at two different scales, and the measurements are compared to determine how much high-resolution data the image contains compared to low-resolution data. The texture measurement may, for example, be a Brenner auto-focus score calculated from the means of adjacent pairs of pixels for the high-resolution measurement and from the means of adjacent triples of pixels for the low-resolution measurement. A score indicative of the quality of focus is then established based on a function of the low-resolution and high-resolution measurements. This score may be used by an automated imaging device to verify that image quality is acceptable. The device may adjust the focus and acquire new images to replace any that are deemed unacceptable. |
| FILED | Monday, April 26, 2010 |
| APPL NO | 12/767316 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014853 | Kraus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Nina Kraus (Evanston, Illinois); Trent Nicol (Chicago, Illinois) |
| ABSTRACT | A system and method of central auditory processing testing and evaluation provides for identifying clinically relevant neural synchrony in the auditory brainstem pathway. The system or method finds use as a tool to evaluate auditory processing disorders, and hence, potential auditory system and/or learning disabilities. The system or method may further find use in the selection and fitting of hearing corrective appliances such as hearing aid or cochlear implant devices and/or in the selection and implementation of auditory training regimens. |
| FILED | Thursday, May 11, 2006 |
| APPL NO | 11/382805 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/545 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014868 | Greenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert J. Greenberg (Los Angeles, California); Mark S. Humayun (Glendale, California) |
| ABSTRACT | The present invention is an electrode array for neural stimulation. In particular it is an electrode array for use with a visual prosthesis with the electrode array suitable to be positioned on the retina. The array includes multiple attachment points to provide for even pressure across the electrode array surface. The attachment points are arranged so as to not damage retinal tissue stimulated by the electrode array. |
| FILED | Friday, October 24, 2008 |
| APPL NO | 12/258296 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014878 | Greenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert Greenberg (Los Angeles, California); Neil Talbot (Montrose, California); Jordan Neysmith (Pasadena, California); Dilek Guven (Ankara, Turkey); James Little (Saugus, California); Brian Mech (Stevenson Ranch, California); Mark Humayun (Glendale, California) |
| ABSTRACT | Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow. Common flexible circuit fabrication techniques generally require that a flexible circuit electrode array be made flat. Since neural tissue is almost never flat, a flat array will necessarily apply uneven pressure. Further, the edges of a flexible circuit polymer array may be sharp and cut the delicate neural tissue. By applying the right amount of heat to a completed array, a curve can be induced. With a thermoplastic polymer it may be further advantageous to repeatedly heat the flexible circuit in multiple molds, each with a decreasing radius. Further, it is advantageous to add material along the edges. It is further advantageous to provide a fold or twist in the flexible circuit array. Additional material may be added inside and outside the fold to promote a good seal with tissue. |
| FILED | Friday, August 19, 2005 |
| APPL NO | 11/207644 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/152 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014953 | Brenner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Steven E. Brenner (Berkeley, California); Richard E. Green (Berkeley, California); R. Tyler Hillman (Berkeley, California) |
| ABSTRACT | Computational methods for systematically characterizing putative protein isoforms as apparent targets of nonsense-mediated decay (NMD) comprise: (a) identifying a dataset of target putative protein isoform sequences for characterization; (b) identifying from an mRNA dataset corresponding mRNA sequences representing transcripts encoding the protein isoforms; (c) determining corresponding gene intron-exon structures by mapping the mRNA sequences to corresponding genomic sequences; and (d) determining if the transcripts are apparent targets of NMD. Methods for regulating the expression of a gene encoding a protein isoform characterized as an apparent target of NMD comprise biasing expression of the isoform by modulating transcript splicing or modulating NMD activity. |
| FILED | Friday, August 08, 2003 |
| APPL NO | 10/637482 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014957 | Radich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); Rosetta Inpharmatics LLC (Seattle, Washington) |
| INVENTOR(S) | Jerald P. Radich (Sammamish, Washington); Hongyue Dai (Kenmore, Washington); Mao Mao (Kirkland, Washington); Janell M. Schelter (Bellevue, Washington); Peter S. Linsley (Seattle, Washington) |
| ABSTRACT | The invention provides molecular markers that are associated with the progression of chronic myeloid leukemia (CML), and methods and computer systems for monitoring the progression of CML in a patient based on measurements of these molecular markers. The present invention also provides CML target genes, and methods and compositions for treating CML patients by modulating the expression or activity of these CML target genes and/or their encoded proteins. The invention also provides genes that are associated with resistance to imatinib mesylate (Gleevec™) treatment in CML patients, and methods and compositions for determining the responsiveness of a CML patient to imatinib mesylate treatment based on measurements of these genes and/or their encoded proteins. The invention also provides methods and compositions for enhancing the effect of Gleevec™ by modulating the expression or activity of these genes and/or their encoded proteins. |
| FILED | Thursday, December 14, 2006 |
| APPL NO | 11/640517 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08011451 | MacDonald |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | Duncan MacDonald (Houston, Texas) |
| ABSTRACT | A method for forming two or more wellbores in a subsurface formation includes forming a first wellbore in the formation. A second wellbore is directionally drilled in a selected relationship relative to the first wellbore. At least one magnetic field is provided in the second wellbore using one or more magnets in the second wellbore located on a drilling string used to drill the second wellbore. At least one magnetic field is sensed in the first wellbore using at least two sensors in the first wellbore as the magnetic field passes by the at least two sensors while the second wellbore is being drilled. A position of the second wellbore is continuously assessed relative to the first wellbore using the sensed magnetic field. The direction of drilling of the second wellbore is adjusted so that the second wellbore remains in the selected relationship relative to the first wellbore. |
| FILED | Monday, October 13, 2008 |
| APPL NO | 12/250273 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Boring or penetrating the earth 175/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08011598 | Kelly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies, Inc. (Troy, Michigan) |
| INVENTOR(S) | Sean Michael Kelly (Pittsford, New York); Gary Blake (Penfield, New York) |
| ABSTRACT | An improved CHP system combining a VCCHP system with an SOFC system for application as a combined CHP system wherein the compressor motor of a heat pump is powered by a portion of the electricity generated by the SOFC, and wherein the thermal output of the heat pump is increased by abstraction of heat from the SOFC exhaust. This integration allows for complementary operation of each type of system, with the benefits of improved overall fuel efficiency for the improved CHP system. The heat pump is further provided with a plurality of flow-reversing valves and an additional heat exchanger, allowing the heat pump system to be reversed and thus to operate as an air conditioning system. |
| FILED | Wednesday, September 16, 2009 |
| APPL NO | 12/560967 |
| ART UNIT | 3749 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Heating systems 237/12.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012323 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Dileep Singh (Naperville, Illinois); Jules Routbort (Hinsdale, Illinois); Prabir Dutta (Worthington, Ohio); John V. Spirig (North Brunswick, New Jersey); Jiun Chan Yang (Skokie, Illinois) |
| ABSTRACT | A bifunctional total NOx and O2 sensor assembly with an internal reference for high temperature sensing. Two electrochemical total NOx(NO+NO2) measuring systems and method were coupled with a metal/metal oxide internal oxygen reference to detect O2 and NOx simultaneously in a combustion environment using a single sensor. A Pd/PdO-containing reference chamber was sealed within a stabilized zirconia superstructure by a high pressure/temperature bonding method. An amperometric and potentiometric NOx sensor assembly was built on the outside of the Pd/PdO chamber. Pt-loaded zeolite Y was used to obtain total NOx capacity and also to cover the Pt electrodes for detecting oxygen in the presence of NOx. |
| FILED | Wednesday, March 11, 2009 |
| APPL NO | 12/402216 |
| ART UNIT | 1759 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/424 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012380 | Elangovan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | S. Elangovan (South Jordan, Utah); Balakrishnan G. Nair (Sandy, Utah); Troy Small (Midvale, Utah); Brian Heck (Salt Lake City, Utah) |
| ABSTRACT | A multi-phase proton conducting material comprising a proton-conducting ceramic phase and a stabilizing ceramic phase. Under the presence of a partial pressure gradient of hydrogen across the membrane or under the influence of an electrical potential, a membrane fabricated with this material selectively transports hydrogen ions through the proton conducting phase, which results in ultrahigh purity hydrogen permeation through the membrane. The stabilizing ceramic phase may be substantially structurally and chemically identical to at least one product of a reaction between the proton conducting phase and at least one expected gas under operating conditions of a membrane fabricated using the material. In a barium cerate-based proton conducting membrane, one stabilizing phase is ceria. |
| FILED | Wednesday, August 08, 2007 |
| APPL NO | 11/835823 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/518.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012411 | Betty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Rita G. Betty (Rio Rancho, New Mexico); Mark D. Tucker (Albuquerque, New Mexico); John E. Brockmann (Albuquerque, New Mexico); Daniel A. Lucero (Albuquerque, New Mexico); Bruce L. Levin (Tijeras, New Mexico); Jonathan Leonard (Albuquerque, New Mexico) |
| ABSTRACT | Methods and systems for knockdown and neutralization of toxic clouds of aerosolized chemical or biological warfare (CBW) agents and toxic industrial chemicals using a non-toxic, non-corrosive aqueous decontamination formulation. |
| FILED | Monday, February 12, 2007 |
| APPL NO | 11/673835 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012590 | Tomsia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Antoni P. Tomsia (Pinole, California); Eduardo Saiz (Berkeley, California); Jose M. Gomez-Vega (Nagoya, Japan); Sally J. Marshall (Larkspur, California); Grayson W. Marshall (Larkspur, California) |
| ABSTRACT | Glass coatings on metals including Ti, Ti6A14V and CrCo were prepared for use as implants. The composition of the glasses was tailored to match the thermal expansion of the substrate metal. By controlling the firing atmosphere, time, and temperature, it was possible to control the reactivity between the glass and the alloy and to fabricate coatings (25-150 μm thick) with excellent adhesion to the substrate. The optimum firing temperatures ranged between 800 and 840° C. at times up to 1 min in air or 15 min in N2. The same basic technique was used to create multilayered coatings with concentration gradients of hydroxyapatite (HA) particles and SiO2. |
| FILED | Monday, April 30, 2001 |
| APPL NO | 09/845597 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/426 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012739 | Schultz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter G. Schultz (La Jolla, California); Lei Wang (San Diego, California); John Christopher Anderson (San Diego, California); Jason W. Chin (San Diego, California); David R. Liu (Lexington, Massachusetts); Thomas J. Magliery (North Haven, Connecticut); Eric L. Meggers (Philadelphia, Pennsylvania); Ryan Aaron Mehl (San Diego, California); Miro Pastrnak (San Diego, California); Stephen William Santoro (San Diego, California); Zhiwen Zhang (San Diego, California) |
| ABSTRACT | This invention provides compositions and methods for generating components of protein biosynthetic machinery including orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases. Methods for identifying orthogonal pairs are also provided. These components can be used to incorporate unnatural amino acids into proteins in vivo. |
| FILED | Friday, October 26, 2007 |
| APPL NO | 11/978154 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012860 | Elam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Philippe Guyot-Sionnest (Chicago, Illinois) |
| ABSTRACT | A method for producing a product of a functionalized nanocomposition colloidal material using atomic layer deposition to coat the colloidal material. The ALD layer comprises an inorganic material which enables improved optical and electrical properties for the nanocomposite. |
| FILED | Tuesday, June 16, 2009 |
| APPL NO | 12/485784 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/481 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013240 | Forrest et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Fan Yang (Piscataway, New Jersey); Barry P. Rand (Somers, New York) |
| ABSTRACT | A photosensitive device includes a plurality of organic photoconductive materials disposed in a stack between a first electrode and a second electrode, including a first continuous layer of donor host material, a second continuous layer of acceptor host material, and at least one other organic photoconductive material disposed as a plurality of discontinuous islands between the first continuous layer and the second continuous layer. Each of these other photoconductive materials has an absorption spectra different from the donor host material and the acceptor host material. Preferably, each of the discontinuous islands consists essentially of a crystallite of the respective organic photoconductive material, and more preferably, the crystallites are nanocrystals. |
| FILED | Friday, December 01, 2006 |
| APPL NO | 11/566134 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013600 | Yepez, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Esteban Yepez, III (Albuquerque, New Mexico); Dennis P. Roach (Albuquerque, New Mexico); Kirk A. Rackow (Albuquerque, New Mexico); Waylon A. DeLong (Albuquerque, New Mexico) |
| ABSTRACT | A wireless, integrated, mountable, portable, battery-operated, non-contact eddy current sensor that provides similar accuracy to 1970's laboratory scale equipment (e.g., a Hewlett-Packard GP4194A Impedance Analyzer) at a fraction of the size and cost. |
| FILED | Monday, May 12, 2008 |
| APPL NO | 12/119009 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013744 | Tsai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Han-Chung Tsai (Darien, Illinois); Yung Y. Liu (Hinsdale, Illinois) |
| ABSTRACT | An enhanced method and apparatus are provided for tracking and managing a plurality of packagings, particularly packagings containing radioactive and fissile materials. A radio frequency identification (RFID) surveillance tag is provided with an associated packaging. The RFID surveillance tag includes a tag body and a back plate including predefined mounting features for mounting the surveillance tag to the associated packaging. The RFID surveillance tag includes a battery power supply. The RFID surveillance tag includes a plurality of sensors monitoring the associated packaging including a seal sensor. The seal sensor includes a force sensitive material providing a resistivity change responsive to change in a seal integrity change of the associated packaging. The resistivity change causes a seal integrity tag alarm. A tag memory stores data responsive to tag alarms generated by each of the plurality of sensors monitoring the associated packaging. |
| FILED | Friday, April 17, 2009 |
| APPL NO | 12/426054 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Electrical 340/572.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014639 | Skogen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik J. Skogen (Albuquerque, New Mexico); Anna Tauke-Pedretti (Albuquerque, New Mexico) |
| ABSTRACT | An optical NOR gate is formed from two pair of optical waveguide devices on a substrate, with each pair of the optical waveguide devices consisting of an electroabsorption modulator electrically connected in series with a waveguide photodetector. The optical NOR gate utilizes two digital optical inputs and a continuous light input to provide a NOR function digital optical output. The optical NOR gate can be formed from III-V compound semiconductor layers which are epitaxially deposited on a III-V compound semiconductor substrate, and operates at a wavelength in the range of 0.8-2.0 μm. |
| FILED | Thursday, November 13, 2008 |
| APPL NO | 12/270221 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015484 | Backer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alejandro Backer (Altadena, California) |
| ABSTRACT | A method for providing a measure of trust for each participant in a network is disclosed, together with a method to calculate it automatically. In particular, a method for rating online entities, such as online identities is provided, which also takes into account the reputation of the raters. |
| FILED | Friday, February 09, 2007 |
| APPL NO | 11/704730 |
| ART UNIT | 2176 — Graphical User Interface and Document Processing |
| CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/234 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08012382 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Enoch Kim (Boston, Massachusetts); Younan Xia (St. Louis, Missouri); Milan Mrksich (Hinsdale, Illinois); Rebecca J. Jackman (Jamaica Plain, Massachusetts); Xiao-Mei Zhao (Pepper Pike, Ohio); Stephen P. Smith (Medford, Massachusetts); Christian Marzolin (Paris, France); Mara G. Prentiss (Belmont, Massachusetts); George M. Whitesides (Newtown, Massachusetts) |
| ABSTRACT | Chemically or biochemically active agents or other species are patterned on a substrate surface by providing a micromold having a contoured surface and forming, on a substrate surface, a chemically or biochemically active agent or fluid precursor of a structure. A chemically or biochemically active agent or fluid precursor also can be transferred from indentations in an applicator to a substrate surface. The substrate surface can be planar or non-planar. Fluid precursors of polymeric structures, inorganic ceramics and salts, and the like can be used to form patterned polymeric articles, inorganic salts and ceramics, reactive ion etch masks, etc. at the surface. The articles can be formed in a pattern including a portion having a lateral dimension of less than about 1 millimeter or smaller. The indentation pattern of the applicator can be used to transfer separate, distinct chemically or biochemically active agents or fluid precursors to separate, isolated regions of a substrate surface. Waveguide arrays, combinatorial chemical or biochemical libraris, etc. can be made. Differences in refractive index of waveguide and cladding can be created by subjecting the waveguide and cladding, made of indentical prepolymeric material, to different polymerization or cross-linking conditions. Interferometers are defined by coupling arrays of waveguides, where coupling can be controlled by altering the difference in refractive index between cladding and waveguide at any desired location of the array. Alteration and refractive index can be created photochemically, chemically, or the like. Sensors also are disclosed, including biochemical sensors. |
| FILED | Wednesday, March 04, 2009 |
| APPL NO | 12/398132 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/1.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012400 | Mirkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Xiaogang Liu (Evanston, Illinois); Shouwu Guo (Minneapolis, Minnesota) |
| ABSTRACT | Polymeric microstructures and nanostructures can be prepared with use of a tip to pattern a surface. A tip can be used to pattern a structure which can initiate polymerization. The structure can be then exposed to monomer to induce polymerization at the structure. Alternatively, a tip can be used to pattern a surface with a monomer in which the surface is treated with polymerization catalyst so that polymerization occurs at the patterning site. Ring-opening metathesis polymerization can be carried out with use of the tip to control the polymerization. The tip can be a sharp tip as used in for example an atomic force microscope tip. Norbornene types of monomers can be used. Biological macromolecules can be also prepared. |
| FILED | Friday, December 28, 2007 |
| APPL NO | 11/966764 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/494 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012763 | Shende et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Real-Time Analyzers, Inc. (Middletown, Connecticut) |
| INVENTOR(S) | Chetan S. Shende (Ellington, Connecticut); Stuart Farquharson (Meriden, Connecticut); Paul Maksymiuk (South Windsor, Connecticut) |
| ABSTRACT | A stationary medium is employed both to separate chemicals from a sample solution and also to generate surface-enhanced Raman scattering, so that spectral analysis of the separated analyte chemical can be performed. Applied driving force causes the sample to flow into the stationary medium and to distribute therethrough, thereby causing rapid separation of the analyte chemical, and surface-enhanced Raman scattered radiation is quickly detected, at a plurality of locations along a flow path defined by the stationary medium, for ultimate analysis. |
| FILED | Thursday, January 29, 2009 |
| APPL NO | 12/322158 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08013061 — Polyester based degradable materials and implantable biomedical articles formed therefrom
| US 08013061 | Ashby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Valerie Ashby (Durham, North Carolina); David Olson (Minneapolis, Minnesota) |
| ABSTRACT | A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of the first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of the second diacid, wherein the second diacid is different from the first diacid. Prepolymers produced from such processes and articles formed therefrom are also described. |
| FILED | Monday, March 05, 2007 |
| APPL NO | 12/281171 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 525/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013065 | Hedrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | James L. Hedrick (Pleasanton, California); Eric Appel (Palo Alto, California); Robert D. Miller (San Jose, California); Fredrik Nederberg (Greenville, Delaware); Robert M. Waymouth (Palo Alto, California) |
| ABSTRACT | A method for making a multi-branched polymer includes reacting a first polymeric unit with a functional cyclic compound to form a functional macroinitiator compound with a cyclic moiety. The functional macroinitiator compound is reacted with an amine functional compound to open the cyclic moiety and form a first functional group and a second functional group. To form the branched polymer, at least one of a second polymeric unit is propagated from the first functional group and a third polymeric unit is propagated from the second functional group. |
| FILED | Tuesday, June 09, 2009 |
| APPL NO | 12/481477 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 525/107 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013994 | Vattiat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cyber Materials LLC (Auburndale, Massachusetts) |
| INVENTOR(S) | Brian Louis Vattiat (Austin, Texas); Donald Edward Wroblewsky (Wellesley, Massachusetts); Michael Alan Gevelber (Auburndale, Massachusetts) |
| ABSTRACT | A method of measuring parameters of a particle includes providing a particle, wherein the particle has a first portion and a second portion. The process includes providing a column of photo-detectors including a first photo-detector and a second photo-detector, wherein the first photo-detector and the second photo-detector are sensitive to the same range of light frequencies. Light is projected from the particle onto the column of photo-detectors wherein the column of photo-detectors is oriented so the light from the first portion is projected onto the first photo-detector and light from the second portion is projected onto the second photo-detector. Light measured by the first photo-detector differs from light measured by the second photo-detector. The process further includes using the different first and the second photo-detector measurements to determine at least one from the group consisting of particle temperature and particle diameter. |
| FILED | Monday, January 14, 2008 |
| APPL NO | 12/008787 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/335 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014494 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Cedric X. Yu (Clarksville, Maryland); Shuang Luan (Albuquerque, New Mexico); Danny Z. Chen (Granger, Indiana); Matthew A. Earl (Crownsville, Maryland); Chao Wang (Columbia, Maryland) |
| ABSTRACT | Provided herein are methods and systems for designing a radiation treatment for a subject using single arc dose painting. The methods and systems comprise an algorithm or a computer-readable product having the same, to plan the radiation treatment. The algorithm converts pairs of multiple leaf collimation (MLC) leaves to sets of leaf aperture sequences that form a shortest path single arc thereof where the pairs of MLC leaves each aligned to an intensity profile of densely-spaced radiation beams, and connects each single arc of leaf apertures to form a final treatment single arc. Also provided is a method for irradiating a tumor in a subject using single arc dose painting. |
| FILED | Tuesday, October 20, 2009 |
| APPL NO | 12/589205 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08014809 | Bar-Ness et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Yeheskel Bar-Ness (Marlboro, New Jersey); Osvaldo Simeone (Hoboken, New Jersey); Igor Stanojev (Harrison, New Jersey) |
| ABSTRACT | Power control for uplink channels with non-cooperative and rational mobile stations (MS) provided using game theory. As a game leader, a multi-antenna access point (AP) determines the network parameters (bandwidth and the number of receiving antennas) for the power control game played between the mobile stations (MSs) (follower), so as to maximize the network utility per system resource (bandwidth and antennas). |
| FILED | Tuesday, December 11, 2007 |
| APPL NO | 12/001470 |
| ART UNIT | 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/522 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015125 | Regli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | William C. Regli (Philadelphia, Pennsylvania); Ali Shokoufandeh (New Hope, Pennsylvania); Dmitriy Bespalov (Philadelphia, Pennsylvania) |
| ABSTRACT | A scale-Space feature extraction technique is based on recursive decomposition of polyhedral surfaces into surface patches. The experimental results show that this technique can be used to perform matching based on local model structure. Scale-space techniques can be parameterized to generate decompositions that correspond to manufacturing, assembly or surface features relevant to mechanical design. One application of these techniques is to support matching and content-based retrieval of solid models. Scale-space technique can extract features that are invariant with respect to the global structure of the model as well as small perturbations that 3D laser scanning may introduce. A new distance function defined on triangles instead of points is introduced. This technique offers a new way to control the feature decomposition process, which results in extraction of features that are more meaningful from an engineering viewpoint. The technique is computationally practical for use in indexing large models. |
| FILED | Thursday, August 30, 2007 |
| APPL NO | 11/847942 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015179 | Koudas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | AT and T Intellectual Property II, L.P. (Atlanta, Georgia); National Science Foundation (Arlington, Virginia) |
| INVENTOR(S) | Nikolaos Koudas (Springfield, New Jersey); Divesh Srivastava (Summit, New Jersey); Jignesh M. Patel (Sylvania, Ohio); Shurug Ali Al-Khalifa (Ann Arbor, Michigan); Hosagrahar V. Jagadish (Ann Arbor, Michigan); Yuqing Wu (Windsor, Canada) |
| ABSTRACT | Structural join mechanisms provide efficient query pattern matching. In one embodiment, tree-merge mechanisms are provided. In another embodiment, stack-tree mechanisms are provided. |
| FILED | Monday, November 10, 2008 |
| APPL NO | 12/268444 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/716 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015311 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Polytechnic Institute of New York University (Brooklyn, New York) |
| INVENTOR(S) | Yong Liu (Secaucus, New Jersey) |
| ABSTRACT | A new P2P streaming method and apparatus disseminates video chunks to all peers with the minimum (or at least reduced) delay. After obtaining a new video chunk, a peer keeps transmitting (uploading) that video chunk to other peers until all peers receive it. The approach quickly increases the aggregate bandwidth that can be utilized to transmit a video chunk. For example, the aggregate peer bandwidth used to transmit a video chunk can double every time slot. For a homogeneous P2P streaming system with N peers, a time slot is defined as a unit of the single chunk transmission delay between two peers. Using the P2P streaming method, a video chunk can be disseminated to all peers within 1+log2 N time slots. |
| FILED | Monday, September 22, 2008 |
| APPL NO | 12/235310 |
| ART UNIT | 2453 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08012242 | Kozliak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Dakota (Grand Forks, North Dakota) |
| INVENTOR(S) | Evguenii I. Kozliak (Grand Forks, North Dakota); Wayne S. Seames (Grand Forks, North Dakota) |
| ABSTRACT | A method of removing pollutants from building materials using an externally applied adsorbent. The adsorbent has a high affinity to common pollutant chemicals. The pollutants are transferred from the contaminated microporous building materials onto the adsorbent until sufficient amounts of pollutant chemicals are reduced to make the building materials acceptable and safe to use. The adsorbent may be regenerated and reused or treated as a waste. |
| FILED | Friday, August 31, 2007 |
| APPL NO | 11/897758 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation: Processes 095/141 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012730 | Donovan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | David M. Donovan (Baltimore, Maryland) |
| ABSTRACT | The Staphylococcus aureus bacteriophage phi11 endolysin has two peptidoglycan hydrolase domains (endopeptidase and amidase) and a SH3b cell wall-binding domain. In turbidity reduction assays, the purified protein can lyse untreated staphylococcal mastitis-causing pathogens, S. aureus and coagulase negative staphylococci (S. chronogenes, S. epidermis, S. hyicus, S. simulans, S. warneri, and S. xylocus), making it a strong antimicrobial protein and an effective candidate for treating multidrug-resistant staphylococci. Lytic activity is maintained at the pH (6.7) and the ‘free’ calcium concentration (3 mM) of milk. Truncated endolysin-derived proteins, containing just the endopeptidase domain, also lyse staphylococci, in the absence of the SH3b-binding domain. |
| FILED | Tuesday, August 29, 2006 |
| APPL NO | 11/511848 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/195 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013213 | Mau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Christopher J. D. Mau (Pullman, Washington); Katrina Cornish (Vista, California) |
| ABSTRACT | Transgenic guayule lines were created by constitutively expressing transgenes that encode for prenyltransferase and allylic diphosphate synthase. These new lines are important to rubber production because they result in plants that produce latex rubber which is lower in guayulin, a compound that produces a skin irritation in some animals. Controlling prenyltransferase production also permits the control of the production of resin by the plants, which has important industrial implications. Additionally, prenyltransferase manipulation can result in latex particles of different size, containing rubber of different molecular weight, which is also significant to industrial production. Although the elevated prenyltransferase activity in the transgenic lines resulted in shorter rubber molecules, the number of rubber molecules made by these transgenic lines was increased. |
| FILED | Wednesday, November 23, 2005 |
| APPL NO | 11/285918 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08011600 | Gray, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Charles L. Gray, Jr. (Pinckney, Michigan) |
| ABSTRACT | A fuel injector nozzle for use with an internal combustion engine utilizes arrangements of nozzle openings that are designed to increase fuel contact with oxygen within a combustion chamber. Nozzle openings are positioned in more than one plane substantially parallel with the cylinder head surface, with the planes preferably at least 2 millimeters apart, and with the respective pluralities of nozzle openings oriented to provide diverging injection angles in relation to the cylinder head surface. The fuel injector is particularly designed for use with oxygen-dilute (e.g., high EGR) controlled temperature combustion, direct injection compression ignition engines. |
| FILED | Wednesday, December 19, 2007 |
| APPL NO | 12/002944 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012438 | Hutson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Nick D. Hutson (Durham, North Carolina); Ravi K. Srivastava (Cary, North Carolina); Renata Krzyzynska (Wroclaw, Poland); Yongxin Zhao (Cary, North Carolina) |
| ABSTRACT | A method for controlling multipollutant (e.g., SO2, NOx, Hg0 and Hg2+) emissions from a gas stream of a stationary combustion source, an apparatus for controlling multipollutant emissions, and a wet scrubber additive composition for controlling multipollutant emissions are disclosed. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/457955 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012932 | Klinefelter |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Gary R. Klinefelter (Fuquay-Varina, North Carolina) |
| ABSTRACT | Oral, topical and injectable contraceptives, which are based on sperm protein 22 kDa (SP22) polypeptides and antibodies and infertility diagnostics are provided. |
| FILED | Friday, July 22, 2005 |
| APPL NO | 11/572453 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/9.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08011229 | Lieberman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Erez Lieberman (Cambridge, Massachusetts); Katharine E. Forth (Houston, Texas); William H. Paloski (League City, Texas) |
| ABSTRACT | A method for determining postural stability of a person can include acquiring a plurality of pressure data points over a period of time from at least one pressure sensor. The method can also include the step of identifying a postural state for each pressure data point to generate a plurality of postural states. The method can include the step of determining a postural state of the person at a point in time based on at least the plurality of postural states. |
| FILED | Wednesday, November 26, 2008 |
| APPL NO | 12/323912 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/65.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08011941 | Sadick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeybee Robotics, Ltd. (, New York) |
| INVENTOR(S) | Shazad Sadick (Queens Village, New York); Jason Herman (North Bellmore, New York); Dustyn Roberts (New York, New York) |
| ABSTRACT | A connector assembly includes releasably mateable plug and receptacle units. At least one socket is enclosed within the receptacle unit and is aligned with at least one permeable membrane disposed in the front end of the receptacle unit. The plug unit includes a body slidably mounted within a longitudinal bore therein. At least one pin extends from the front end of the body and is aligned with at least one permeable membrane disposed in the front end of the plug unit. The plug unit is biased toward a first, de-mate position in which the body is extended rearwardly such that the pin is enclosed with the plug unit and is slidable to a second, mate position in which the body is compressed forwardly such that the pin projects through the permeable membranes of the plug and receptacle units to electrically connect with the socket. |
| FILED | Tuesday, February 16, 2010 |
| APPL NO | 12/706521 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/271 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012950 | Muir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Peter Muir (Madison, Wisconsin); Ray Vanderby, Jr. (Madison, Wisconsin); Paolo Pepe Provenzano (Madison, Wisconsin) |
| ABSTRACT | Disclosed are methods for detecting and treating joint disease. The methods of diagnosis include determining increased expression of enzymes that are upregulated during the progress of joint and ligament inflammation and degeneration. In addition, disclosed are methods of treating the disease including inhibiting the activity of responsible proteases. |
| FILED | Monday, August 30, 2004 |
| APPL NO | 10/929919 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/152 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08012718 | Ruano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Genomas, Inc. (Hartford, Connecticut) |
| INVENTOR(S) | Gualberto Ruano (Milford, Connecticut); Andreas Windemuth (South Glastonbury, Connecticut); John W. Goethe (Avon, Connecticut) |
| ABSTRACT | The invention is generally directed to a physiogenomic method for predicting diabetes and metabolic syndromes induced by psychotropic drugs. In one embodiment, the invention relates to the use of genetic variants of marker genes to predict the likelihood that an individual will experience undesirable metabolic side effects as a result of the use of a drug including, but not limited to, psychotropic drugs. The invention also relates to methods predicting the likelihood of diabetes and metabolic syndromes induced by the use of drugs with undesirable metabolic side effects. |
| FILED | Friday, March 30, 2007 |
| APPL NO | 11/694247 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013690 | Miyashiro |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | TeraSys Technologies LLC (Honolulu, Hawaii) |
| INVENTOR(S) | Kevin Miyashiro (Honolulu, Hawaii) |
| ABSTRACT | An electronically tuned, absorptive, low-loss notch filter with high RF power handling capability is obtained using a four-port quadrature hybrid coupler connected to a matched pair of band pass resonator devices and resistive terminations. The notch filter design uses series-only tuning elements for the band pass resonator devices to raise the RF power handling of the band pass resonators far above conventional techniques while also being tunable at high speeds. The notch filter architecture and method can be used for interference cancellation in a wide range of wireless technologies, such as cellular phone, wireless routers, hand-held radios, satellite communications, and any other environments where there are a number of wireless technologies in close signal proximity. |
| FILED | Wednesday, February 11, 2009 |
| APPL NO | 12/369256 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/176 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013837 | Schroeder |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Ernest Schroeder (Helotes, Texas) |
| ABSTRACT | The apparatus and method help physically-disabled persons perform point-and-click activities or input text or control characters, which typically require the user to simultaneously control two independent dimensions to select options presented on a computer display. Computer users operate a control in a single dimension (i.e., two directions—first embodiment) or in just one direction (second embodiment). Different input strategies allow a person using the one- or two-directional control method to emulate pointer functions and input characters or character strings. An embodiment augments antagonistic muscle groups for persons exhibiting adequate control in one direction but not the other. An additional embodiment uses available two-dimensional pointers but restricts their operation to one dimension. The output of existing sensors is converted to a form that can be input directly to a computer to be used with a one-dimensional control strategy. |
| FILED | Tuesday, October 11, 2005 |
| APPL NO | 11/248944 |
| ART UNIT | 2629 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08011388 | Fuller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Microstaq, INC (Austin, Texas) |
| INVENTOR(S) | Edward Nelson Fuller (Manchester, Michigan); Harry A. Hunnicutt (Lynden, Washington) |
| ABSTRACT | A MEMS device is disclosed having a single microvalve actuator for controlling multiple microvalves. Exemplary embodiments include a MEMS device including two microvalves formed on a beam positioned by an actuator, the two microvalves controlling separate flow paths between two separate pairs of ports; a device with a two-way pilot operated microvalve and a four-way pilot microvalve for controlling the two-way pilot operated microvalve; a device with two three-way microvalves actuated by a common microvalve actuator; and a two-way microvalve with a moveable microvalve element and a feedback port formed in the moveable element operable to regulate the pressure on an end of the moveable element relative to the movement of the moveable element between the first position and the second position. Also disclosed is a MEMS device including a beam with a plurality of apertures formed therein, resulting in a mass reduction of at least 10 percent. |
| FILED | Friday, March 30, 2007 |
| APPL NO | 11/731729 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/625.650 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08012257 | Morgan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
| INVENTOR(S) | Kenneth E. Morgan (Castleton, New York); Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York) |
| ABSTRACT | Fabrication of doped and undoped stoichiometric polycrystalline AlN ceramics with high purity is accomplished by, for example, reacting Al pellets with nitrogen gas. Such polycrystalline AlN ceramics may be utilized in the fabrication of high purity AlN single crystals, which may be annealed to enhance a conductivity thereof. |
| FILED | Friday, March 30, 2007 |
| APPL NO | 11/731790 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 08013310 | Hoctor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Morpho Detection, Inc. (Newark, California) |
| INVENTOR(S) | Ralph Thomas Hoctor (Saratoga Springs, New York); Scott Stephen Zelakiewicz (Niskayuna, New York) |
| ABSTRACT | An imaging system includes a platform having mounted thereon a coded-aperture imaging device and positioned to receive radiation over a baseline, and a computer configured to acquire a plurality of far-field datasets over the baseline, the plurality of far-field datasets comprising data received via the coded-aperture imaging device, form a first image from the plurality of far-field datasets, and form a second image if the first image indicates presence of a source, the second image formed from the plurality of far-field datasets using an estimated source location from the first image and thereby having a higher contrast than the first image. |
| FILED | Monday, January 05, 2009 |
| APPL NO | 12/348440 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/393 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08015127 | Narzisi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Giuseppe Narzisi (Syracuse, Italy); Bhubaneswar Mishra (Great Neck, New York); Venkatesh Mysore (Piscataway, New Jersey) |
| ABSTRACT | Agent-based models (ABMs)/multi-agent systems (MASs) are one of the most widely used modeling-simulation-analysis approaches for understanding the dynamical behavior of complex systems. These models can be often characterized by several parameters with nonlinear interactions which together determine the global system dynamics, usually measured by different conflicting criteria. One problem that can emerge is that of tuning the controllable system parameters at the local level, in order to reach some desirable global behavior. According to one exemplary embodiment t of the present invention, the tuning of an ABM for emergency response planning can be cast as a multi-objective optimization problem (MOOP). Further, the use of multi-objective evolutionary algorithms (MOEAs) and procedures for exploration and optimization of the resultant search space can be utilized. It is possible to employ conventional MOEAs, e.g., the Nondominated Sorting Genetic Algorithm II (NSGA-II) and the Pareto Archived Evolution Strategy (PAES), and their performance can be tested for different pairs of objectives for plan evaluation. In the experimental results, the approximate Pareto front of the non-dominated solutions is effectively obtained. Further, a conflict between the proposed objectives can be seen. Additional robustness analysis may be performed to assist policy-makers in selecting a plan according to higher-level information or criteria which is likely not present in the original problem description. |
| FILED | Wednesday, September 12, 2007 |
| APPL NO | 11/854468 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08012517 | Woltering et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University And Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | Eugene A. Woltering (Kenner, Louisiana); Conrad A. Hornick (New Orleans, Louisiana); Amy E. Myers (New Orleans, Louisiana) |
| ABSTRACT | Noni juice and a protein-free, alcohol precipitate of Noni juice inhibited angiogenesis in in vitro human angiogenesis models. When growth medium contained Noni juice at least over the range from about 2.5% to about 33% (by volume), angiogenesis was blocked. Moreover, Noni juice and an ethanol precipitate were able to destroy a pre-existing angiogenic response as well as prevent the development of new vessels. Noni juice was effective in inhibiting the growth of angiogenic vessels from breast cancer explants. It will also be effective in treating cancers and non-cancerous diseases whose response includes an increase in angiogenesis, e.g., retinopathy of prematurity, neovascular glaucoma, diabetic retinopathy, and psoriasis. The primary antiangiogenic component is believed to be a carbohydrate with a molecular weight less than about 6000 Daltons. In an initial experiment, oral administration of Noni juice appeared to adversely affect the antioangiogenic component(s) in the juice. |
| FILED | Friday, August 30, 2002 |
| APPL NO | 10/488176 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/769 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08013120 | Du Clos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Terry W. Du Clos (Albuquerque, New Mexico); Carolyn Mold (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to the use of C-reactive protein, its mutants, metabolites and polypeptides and related compounds thereof for the treatment of various disease states and conditions associated with systemic lupus erythematosus (SLE), including lupus of the skin (discoid), systemic lupus of the joints, lungs and kidneys, hematological conditions including hemolytic anemia and low lymphocyte counts, lymphadenopathy and CNS effects including memory loss, seizures and psychosis, among numerous others as otherwise disclosed herein, hi another aspect of the invention, the reduction in the likelihood that a patient who is at risk for an outbreak of a disease state or condition with systemic lupus erythematosus will have an outbreak is an additional aspect of the present invention. |
| FILED | Thursday, October 26, 2006 |
| APPL NO | 12/083055 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 08013789 | van Graas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ohio University (Athens, Ohio) |
| INVENTOR(S) | Frank van Graas (Lancaster, Ohio); Andrey Soloviev (The Plains, Ohio); Sanjeev Gunawardena (Athens, Ohio) |
| ABSTRACT | A receiver for continuous carrier phase tracking of low carrier-to-noise ratio (“CNR”) signals from a plurality of radio navigation satellites while the receiver is mobile. The receiver may have: a radio frequency (RF) front-end that provides satellite data corresponding to signals received from the plurality of radio navigation satellites; an inertial measurement unit (IMU) that provides inertial data; and a processor circuit in circuit communication with the RF front end and the IMU, the processor circuit being capable of using satellite data from the RF front-end and inertial data from the IMU to perform continuous carrier phase tracking of low CNR radio navigation satellite signals having a CNR of about 20 dB-Hz, while the receiver is mobile. The receiver may be a GPS receiver for continuous carrier phase tracking of low-CNR GPS signals. |
| FILED | Thursday, September 22, 2005 |
| APPL NO | 11/233531 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/357.460 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Library of Congress (LOC)
| US 08015125 | Regli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | William C. Regli (Philadelphia, Pennsylvania); Ali Shokoufandeh (New Hope, Pennsylvania); Dmitriy Bespalov (Philadelphia, Pennsylvania) |
| ABSTRACT | A scale-Space feature extraction technique is based on recursive decomposition of polyhedral surfaces into surface patches. The experimental results show that this technique can be used to perform matching based on local model structure. Scale-space techniques can be parameterized to generate decompositions that correspond to manufacturing, assembly or surface features relevant to mechanical design. One application of these techniques is to support matching and content-based retrieval of solid models. Scale-space technique can extract features that are invariant with respect to the global structure of the model as well as small perturbations that 3D laser scanning may introduce. A new distance function defined on triangles instead of points is introduced. This technique offers a new way to control the feature decomposition process, which results in extraction of features that are more meaningful from an engineering viewpoint. The technique is computationally practical for use in indexing large models. |
| FILED | Thursday, August 30, 2007 |
| APPL NO | 11/847942 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08012796 | Andry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Paul S. Andry (Yorktown Heights, New York); John M. Cotte (New Fairfield, Connecticut); John U. Knickerbocker (Monroe, New York); Cornelia K. Tsang (Mohegan Lake, New York) |
| ABSTRACT | Apparatus and methods are provided for high density packaging of semiconductor chips using silicon space transformer chip level package structures, which allow high density chip interconnection and/or integration of multiple chips or chip stacks high I/O interconnection and heterogeneous chip or function integration. |
| FILED | Monday, August 10, 2009 |
| APPL NO | 12/538223 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/107 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 06, 2011.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2011/fedinvent-patents-20110906.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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