FedInvent™ Patents
Patent Details for Tuesday, November 29, 2011
This page was updated on Monday, March 27, 2023 at 02:05 AM GMT
Department of Health and Human Services (HHS)
| US 08066914 | Hu |
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| ASSIGNEE(S) | University of Akron (Akron, Ohio) |
| INVENTOR(S) | Jun Hu (Fairlawn, Ohio) |
| ABSTRACT | 7-ethynyl-2,4,9-trithiaadamantane and related methods are presented. Manufacturing 7-ethynyl-2,4,9-trithiaadamantane includes the steps of: (1) reducing alkyl 2,4,9-trithiaadamantane-7-carboxylate to produce 7-hydroxymethyl-2,4,9-trithiaadamantane; (2) oxidizing 7-hydroxymethyl-2,4,9-trithiaadamantane to produces 7-carbonyl-2,4,9-trithiaadamantane; and (3) reacting 7-carbonyl-2,4,9-trithiaadamantane with Ohira-Bestmann reagent to produces 7-ethynyl-2,4,9-trithiaadamantane. Molecular wires having 2,4,9-trithiaadamantane surface anchors are also disclosed. |
| FILED | Friday, October 31, 2008 |
| APPL NO | 12/262871 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Compositions 252/519.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066973 | Kuppusamy et al. |
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| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Periannan Kuppusamy (New Albany, Ohio); Vijay Kutala (Columbus, Ohio); Jay L. Zweier (Columbus, Ohio); Pawel Kwiatkowski (Dublin, Ohio) |
| ABSTRACT | A new class of micro- and nano- particulate paramagnetic spin probes useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro. |
| FILED | Wednesday, March 01, 2006 |
| APPL NO | 11/365798 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066983 | Wimmer et al. |
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| ASSIGNEE(S) | The Research Foundation of State University of New York (Albany, New York) |
| INVENTOR(S) | Eckard Wimmer (E. Setauket, New York); Jeronimo Cello (Port Jefferson, New York); Aniko Paul (Setauket, New York); Hidemi Toyoda (E. Setauket, New York); Jiang Yin (Port Jefferson, New York) |
| ABSTRACT | A novel and stable attenuated poliovirus, which replicates in neuroblastoma cells, is produced by engineering an indigenous replication element (cre), into the 5′ non-translated genomic region and inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus replicates in a neuroblastoma model (Neuro-2aCD155 tumors) expressing CD155, the poliovirus receptor, and is effective for oncolytic treatment and cure of solid tumors, such as neuroblastoma. |
| FILED | Monday, March 16, 2009 |
| APPL NO | 12/405068 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067010 | Koelle et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | David M. Koelle (Seattle, Washington); Lawrence Corey (Mercer Island, Washington) |
| ABSTRACT | The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are antigens and/or their constituent epitopes confirmed to be recognized by T-cells derived from herpetic lesions or from uterine cervix. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection. |
| FILED | Monday, May 10, 2010 |
| APPL NO | 12/777156 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/186.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067014 | Kay et al. |
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| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Mark Kay (Los Altos, California); Dirk Grimm (Palo Alto, California) |
| ABSTRACT | Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a library from which the capsids are selected are also provided. |
| FILED | Monday, August 10, 2009 |
| APPL NO | 12/538791 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/233.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067021 | Buehrer et al. |
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| ASSIGNEE(S) | Affinergy, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Benjamin Marcus Buehrer (Chapel Hill, North Carolina); Paul Hamilton (Cary, North Carolina); Dalia Juzumiene (Cary, North Carolina); Shrikumar Nair (Cary, North Carolina); Yuchen Chen (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions. |
| FILED | Thursday, September 04, 2008 |
| APPL NO | 12/204731 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/422 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067152 | Beretta |
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| ASSIGNEE(S) | The Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Laura Beretta (Mercer Island, Washington) |
| ABSTRACT | A method of detecting whether a subject is afflicted with or at increased risk of developing liver cancer is carried out by detecting cleavage of a marker in a sample such as a blood sample from the subject. Suitable markers include but are not limited to, calreticulin, calreticulin precursor, protein disulfide isomerase family A member 3 (PDIA3), and cleavage products thereof. The cleavage, or extent of cleavage, can be as compared to that found in a control sample. |
| FILED | Tuesday, February 20, 2007 |
| APPL NO | 11/708202 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067158 | Brzustowicz |
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| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Linda M. Brzustowicz (Madison, New Jersey) |
| ABSTRACT | Compositions and methods relating to the diagnosis and treatment of neuropsychiatric disorders, such as schizophrenia, schizoaffective disorders, and bipolar disorders are disclosed. Also provided are methods for screening therapeutic agents having efficacy for the treatment of such disorders. |
| FILED | Thursday, January 26, 2006 |
| APPL NO | 11/814906 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067159 | Brown et al. |
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| ASSIGNEE(S) | Applied Biosystems, LLC (Carlsbad, California); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | James F. Brown (Clifton, Virginia); Jonathan E. Silver (Bethesda, Maryland) |
| ABSTRACT | A microfluidic device comprising a first surface portion and a first sample retaining element, which have differing affinities to a fluid, and a method comprising supplying a sample to such a device. In some embodiments, the differing affinity is a result of plasma, ion embedding, surface charging, chemical, optical, electronic and/or electromagnetic treatment. Also, a microfluidic device comprising at least one microcapillary device having a sample retaining element, at least one surface of which exhibits hydrophobicity, hydrophilicity, electromagnetic force exertion and electrostatic force exertion. Also, a microfluidic device comprising a first element having a hydrophilic pattern comprising at least a first sample retaining element. Also, a method comprising supplying a sample to a channel between a first element and a second element, and inducing in the first element at least one hydrophilic pattern by electrets or by internal or external electrodes to provide a charged surface. |
| FILED | Monday, August 13, 2007 |
| APPL NO | 11/837600 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067160 | Brennan et al. |
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| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Mark David Brennan (Jeffersonville, Indiana); D. Kay Phillips (Louisville, Kentucky) |
| ABSTRACT | The invention includes method of determining if a subject has a genetic predisposition to clinically diagnosed schizophrenia (SZ), schizotypal personality disorder (SPD), and/or schizoaffective disorder (SD). |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/859168 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067192 | Kalkum et al. |
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| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Markus Kalkum (Azusa, California); Karine Bagramyan (North Hollywood, California) |
| ABSTRACT | Provided herein is a large immuno-sorbent surface area assay (ALISSA) for rapid and sensitive detection of toxin or enzyme activity. This assay is designed to capture a low number of toxin or enzyme molecules and to measure their intrinsic protease activity via conversion of a fluorogenic or luminescent substrate. The ALISSA is significantly faster and more sensitive than methods routinely utilized in the art. This assay is applicable for use for detection of a variety of toxins or enzymes having proteolytic activity, such as botulinum neurotoxin, bacillus anthracis lethal factor, human chitinases, and aspergillus fumigatus proteases. Also provided are methods for constructing and identifying novel luminescent or fluorescent substrates suitable for use with the ALISSA method. |
| FILED | Thursday, June 05, 2008 |
| APPL NO | 12/134092 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.940 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067196 | Rosenberg et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert D. Rosenberg (Cambridge, Massachusetts); Lijuan Zhang (St. Charles, Missouri); David L. Beeler (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed are methods of 6-O-sulfating glucosaminyl N-acetylglucosamine residues (GlcNAc) in a polysaccharide preparation and methods of converting anticoagulant-inactive heparan sulfate to anticoagulant-active heparan sulfate and substantially pure polysaccharide preparations may by such methods. Also disclosed is a mutant CHO cell which hyper-produces anticoagulant-active heparan sulfate. Methods for elucidating the sequence of activity of enzymes in a biosynthetic pathway are provided. |
| FILED | Thursday, March 28, 2002 |
| APPL NO | 10/473180 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/68.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067230 | Wilson et al. |
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| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Elaine Lynette Wilson (New York, New York); Patricia Burger (Bloubergstrand, South Africa) |
| ABSTRACT | Prostatic stem cells have been isolated. Benign prostatic hyperplasia and other proliferative diseases of the prostate may arise in prostatic stem cells. The prostatic stem cells are used as a research tool for studying cancer and other proliferative diseases of the prostate, and for developing diagnostics and therapeutics for proliferative diseases of the prostate. Antibodies to the antigens expressed by prostatic stem cells can be used as therapeutics or diagnostics or can be used to deliver therapeutic or diagnostic agents directly to the prostatic stem cells. |
| FILED | Tuesday, May 10, 2005 |
| APPL NO | 11/596351 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067237 | Mooney et al. |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | David J. Mooney (Sudbury, Massachusetts); Omar Abdel-Rahman Ali (Bloomington, Minnesota); Eduardo Alexandre Barros e Silva (Somerville, Massachusetts); Hyun Joon Kong (Cambridge, Massachusetts); Elliott Earl Hill, Jr. (Ypsilanti, Michigan); Tanyarut Boontheekul (Bangkok, Thailand) |
| ABSTRACT | A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material. |
| FILED | Wednesday, December 13, 2006 |
| APPL NO | 11/638796 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067239 | Murphy |
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| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Kenan C. Murphy (Natick, Massachusetts) |
| ABSTRACT | The present invention features homologous recombination methods and systems. The methods and systems promote highly efficient homologous recombination in cells (e.g., in prokaryotic cells). The methods and systems are useful, for example, in pharmaceutical drug development, vaccine development and cloning. |
| FILED | Monday, December 22, 2008 |
| APPL NO | 12/341882 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/488 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067365 | Westenfelder |
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| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Christof Westenfelder (Salt Lake City, Utah) |
| ABSTRACT | The compositions and methods disclosed herein are for prevention or treatment of multi-organ failure with erythropoietin. The usefulness of the present invention is that erythropoietin may act to prevent the onset of MOF in a patient at risk of developing it. The present invention may further lessen the effect in one or more affected organs in a patient at risk of developing MOF or in one already diagnosed with it. |
| FILED | Tuesday, November 22, 2005 |
| APPL NO | 11/791287 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/7.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067368 | Robertson et al. |
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| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio); Nationwide Children's Hospital, Inc. (Columbus, Ohio) |
| INVENTOR(S) | Fredika Robertson (Dublin, Ohio); John Bauer (Columbus, Ohio) |
| ABSTRACT | Vascular endothelial growth factor alternative splice variants and methods of their use are provided. |
| FILED | Thursday, January 27, 2005 |
| APPL NO | 10/597509 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/8.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067377 | Arap et al. |
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| ASSIGNEE(S) | The Board of Regents of the University of Texas systems (Austin, Texas) |
| INVENTOR(S) | Wadih Arap (Houston, Texas); Renata Pasqualini (Houston, Texas) |
| ABSTRACT | The present invention concerns methods and compositions for in vivo and in vitro targeting. A large number of targeting peptides directed towards human organs, tissues or cell types are disclosed. The peptides are of use for targeted delivery of therapeutic agents, including but not limited to gene therapy vectors. A novel class of gene therapy vectors is disclosed. Certain of the disclosed peptides have therapeutic use for inhibiting angiogenesis, inhibiting tumor growth, inducing apoptosis, inhibiting pregnancy or inducing weight loss. Methods of identifying novel targeting peptides in humans, as well as identifying endogenous receptor-ligand pairs are disclosed. Methods of identifying novel infectious agents that are causal for human disease states are also disclosed. A novel mechanism for inducing apoptosis is further disclosed. |
| FILED | Tuesday, May 29, 2007 |
| APPL NO | 11/754761 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067389 | Kumar et al. |
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| ASSIGNEE(S) | The Broad of Trustees of the University of Illinois (Chicago, Illinois) |
| INVENTOR(S) | Nalin M. Kumar (Wilmette, Illinois); Beatrice Yue (Deerfield, Illinois); Shahid Siddiqui (Wilmette, Illinois); Asrar B. Malik (Hinsdale, Illinois); Jose S. Pulido (Rochester, Minnesota) |
| ABSTRACT | The present application is directed to siRNA-based silencing of the type II receptor of TGFβ. siRNAs that target this receptor abrogate the receptor protein and transcript, TGFβ-mediated processes such as fibronectin assembly and cell migration also are inhibited and the molecules of the invention are efficacious in reducing the inflammatory response and matrix deposition. These findings show that siRNAs can be successfully delivered both in vitro and in vivo to regulate the TGFβ type II receptor level and modulate wound response. Methods and compositions exploiting the findings of the present invention have a wide-ranging application, extending from treatment of disorders of the eye to other organs and tissues throughout the body. |
| FILED | Monday, July 20, 2009 |
| APPL NO | 12/505911 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067390 | Merritt et al. |
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| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | William M. Merritt (Houston, Texas); Anil K. Sood (Pearland, Texas); Menashe Bar-Eli (Houston, Texas); Gabriel Lopez-Berestein (Bellaire, Texas) |
| ABSTRACT | The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmaceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein. |
| FILED | Friday, February 29, 2008 |
| APPL NO | 12/527684 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067394 | Honda et al. |
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| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Tadashi Honda (Hanover, New Hampshire); Chitra Sundararajan (Hamilton, Canada); Gordon W. Gribble (Lebanon, New Hampshire); Michael B. Sporn (Tunbridge, Vermont); Karen T. Liby (West Lebanon, New Hampshire) |
| ABSTRACT | This invention describes novel tricyclic-bis-enone derivatives (TBEs), such as TBE-31, TBE-34, TBE-45 and water-soluble TBEs. The methods of preparing these compounds are also disclosed. The inventors demonstrate the ability of these new TBEs to inhibit proliferation of human myeloma cells, inhibit the induction of iNOS in cells stimulated with interferon-γ, induce heme oxygenase-1 (HO-1), induce CD11b expression—a leukemia differentiation marker, inhibit proliferation of leukemia cells, induce apoptosis in human lung cancer, and induce apoptosis in other cancerous cells. The TBEs of this invention are expected to be useful agents for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress. |
| FILED | Monday, May 10, 2010 |
| APPL NO | 12/777120 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/63 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067430 | Ugen et al. |
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| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Kenneth E. Ugen (Tampa, Florida); Steven Specter (Tampa, Florida); Susan B. Nyland (Hershey, Pennsylvania); Chuanhai Cao (Tampa, Florida) |
| ABSTRACT | A method of treating HIV infection by using the novel anti-HIV activity of the opioid antagonist naloxone. |
| FILED | Thursday, July 29, 2004 |
| APPL NO | 10/902471 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067432 | Anderson et al. |
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| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Bradley D. Anderson (Lexington, Kentucky); Vijay Joguparthi (Danbury, Connecticut); Tian-Xiang Xiang (Lexington, Kentucky) |
| ABSTRACT | A method for preparing a stable dispersion of a camptothecin, camptothecin prodrug, or analog thereof for administration to a patient in need thereof includes preparing a solution of the camptothecin, wherein the solution has a pH which places substantially an entirety of that camptothecin in a carboxylate form. The camptothecin may be a neutral camptothecin. The solution is next loaded into a liposome including at least one lipid, which may be a phospholipid. An intraliposomal pH is maintained which preserves substantially an entirety of the camptothecin in the carboxylate form. The liposomal dispersion is administered to an individual in need thereof, whereby the liposomes accumulate at and permeate into tumor tissue and an active, lactone form camptothecin is released in situ at the tumor site. Compositions formulated in accordance with the described method for treatment of a cancer in an animal in need thereof are provided also. |
| FILED | Monday, March 31, 2008 |
| APPL NO | 12/058794 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067462 | Danishefsky et al. |
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| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Samuel J. Danishefsky (Englewood, New Jersey); Silas P. Cook (New York, New York) |
| ABSTRACT | A compound having the structure of the formula (genus of compound 1 excluding Tashironin or Debenzoyltashironin) and methods of the same. |
| FILED | Tuesday, December 20, 2005 |
| APPL NO | 11/793646 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/468 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067465 | Honda et al. |
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| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Tadashi Honda (Hanover, New Hampshire); Frank G. Favaloro (Norfolk, Massachusetts); Gordon W. Gribble (Lebanon, New Hampshire); Michael B. Sporn (Tunbridge, Vermont); Nanjoo Suh (White River Junction, Vermont) |
| ABSTRACT | Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral sclerosis, rheumatoid arthritis, inflammatory bowel disease, and all other diseases whose pathogenesis is believed to involve excessive production of either nitric oxide (NO) or prostaglandins or the overexpression of iNOS or COX-2 genes or gene products. Further, methods for the synthesis of the TBE compounds of the invention utilize cheap commercially available reagents and are highly cost effective and amenable to scale-up. Additional high efficiency synthetic methods that utilize novel intermediates as well as the synthesis of these intermediates are also provided. Furthermore, the invention also provides methods for designing novel and water-soluble TBEs. |
| FILED | Thursday, March 11, 2010 |
| APPL NO | 12/722053 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/519 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067472 | Richon et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Merck HDAC Research, LLC (Boston, Massachusetts); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Victoria M. Richon (Rye, New York); Judy H. Chiao (Berkeley Heights, New Jersey); William Kevin Kelly (Scotch Plains, New Jersey); Thomas A. Miller (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides methods of selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells, and/or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inhibitors. The oral bioavailability of the active compounds in the pharmaceutical compositions of the present invention is surprisingly high. Moreover, the pharmaceutical compositions unexpectedly give rise to high, therapeutically effective blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors in vivo. |
| FILED | Friday, April 23, 2010 |
| APPL NO | 12/799368 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/575 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067530 | O'Keefe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Barry R. O'Keefe (Frederick, Maryland); Chang-yun Xiong (Bloomingdale, New Jersey); James B. McMahon (Frederick, Maryland); Andrew Byrd (Bethesda, Maryland) |
| ABSTRACT | A scytovirin domain 1 (SD1) polypeptide, a nucleic acid encoding the polypeptide, and related fusion proteins, conjugates, isolated cells, vectors, and antibodies, as well as a method of inhibiting a viral infection using the same. |
| FILED | Wednesday, May 24, 2006 |
| APPL NO | 11/914833 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067535 | Terajima et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Masanori Terajima (Holden, Massachusetts); John Cruz (Shrewbury, Massachusetts); Francis A. Ennis (Shrewsbury, Massachusetts) |
| ABSTRACT | The present invention relates to the identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes. Three vaccinia virus CD8+ T cell epitopes restricted by the most common human M.C. class I allele, HLA-A0201, were identified. Each of these epitopes is highly conserved in vaccinia and variola viruses. In addition, the induction of the T cell responses following primary vaccination with two of these epitopes is demonstrated by the kinetics of epitope specific CD8+ T cells in 3 HLA-A0201 individuals. Two vaccinia virus CD8+ T cell epitopes restricted by another common human M.C. class I allele, HLA-B7, also were identified. Both epitopes are highly conserved in vaccinia and variola viruses. This information will be useful for the design and analysis of the immunogenicity of experimental vaccinia vaccines, and for basic studies of human T cell memory. |
| FILED | Wednesday, September 28, 2005 |
| APPL NO | 11/238122 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067551 | Gerngross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Glycofi, Inc. (Lebanon, New Hampshire) |
| INVENTOR(S) | Tillman U. Gerngross (Hanover, New Hampshire); Stefan Wildt (Lebanon, New Hampshire); Byung-Kwon Choi (Norwich, Vermont); Juergen Hermann Nett (Enfield, New Hampshire); Piotr Bobrowicz (Enfield, New Hampshire); Stephen R Hamilton (Enfield, New Hampshire); Robert C. Davidson (Enfield, New Hampshire) |
| ABSTRACT | The present invention relates to eukaryotic host cells having modified oligosaccharides which may be modified further by heterologous expression of a set of glycosyltransferases, sugar transporters and mannosidases to become host-strains for the production of mammalian, e.g., human therapeutic glycoproteins. The invention provides nucleic acid molecules and combinatorial libraries which can be used to successfully target and express mammalian enzymatic activities such as those involved in glycosylation to intracellular compartments in a eukaryotic host cell. The process provides an engineered host cell which can be used to express and target any desirable gene(s) involved in glycosylation. Host cells with modified oligosaccharides are created or selected. N-glycans made in the engineered host cells have a Man5GlcNAc2 core structure which may then be modified further by heterologous expression of one or more enzymes, e.g., glycosyltransferases, sugar transporters and mannosidases, to yield human-like glycoproteins. For the production of therapeutic proteins, this method may be adapted to engineer cell lines in which any desired glycosylation structure may be obtained. |
| FILED | Friday, November 07, 2008 |
| APPL NO | 12/291373 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/395 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067553 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mountain View Pharmaceuticals, Inc. (Menlo Park, California); Duke University (Durham, North Carolina) |
| INVENTOR(S) | L. David Williams (Fremont, California); Michael S. Hershfield (Durham, North Carolina); Susan J. Kelly (Chapel Hill, North Carolina); Mark G. P. Saifer (San Carlos, California); Merry R. Sherman (San Carlos, California) |
| ABSTRACT | A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme. |
| FILED | Wednesday, April 28, 2010 |
| APPL NO | 12/769570 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/412 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067558 | Nudler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Evgeny A. Nudler (New York, New York); Ilya Shamovsky (New Providence, New Jersey) |
| ABSTRACT | The present invention provides a novel RNA, designated herein as the “HSR1” (Heat Shock RNA), constitutively active HSR1 fragments, and the use of HSR1 and constitutively active HSR1 fragments for generation of novel therapeutics for the treatment of various diseases in animals and for generation of stress-resistant plants. |
| FILED | Friday, October 31, 2008 |
| APPL NO | 12/263140 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067563 | Harris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Curtis C. Harris (Garrett Park, Maryland); Makoto Nagashima (Kiryu, Japan) |
| ABSTRACT | The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods of diagnosing and treating tumors with such nucleic acids and proteins. |
| FILED | Monday, March 15, 2010 |
| APPL NO | 12/724305 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067565 | Kinney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sanofi Pasteur (Lyons, France); Centers For Disease Control and Prevention (Atlanta, Georgia) |
| INVENTOR(S) | Richard Kinney (Fort Collins, Colorado); Claire Y. H. Kinney (Fort Collins, Colorado); Véronique Barban (Craponne, France); Jean Lang (Mions, France); Bruno Guy (Lyons, France) |
| ABSTRACT | The invention relates to live attenuated VDV1 (VERO-Derived Dengue serotype 1 virus) strains which have been derived from the wild-type dengue-1 strain 16007 by passaging on PDK and sanitization on Vero cells and nucleic acids thereof. The invention further relates to a vaccine composition which comprises a VDV1 strain. |
| FILED | Tuesday, December 08, 2009 |
| APPL NO | 12/633411 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.720 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067566 | Kinney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sanofi Pasteur (Lyons, France); Centers for Disease Control and Prevention (Atlanta, Georgia) |
| INVENTOR(S) | Richard Kinney (Fort Collins, Colorado); Claire Y. H. Kinney (Fort Collins, Colorado); Véronique Barban (Craponne, France); Jean Lang (Mions, France); Bruno Guy (Lyons, France) |
| ABSTRACT | The invention relates to live attenuated VDV2 (VERO-Derived Vaccine Dengue serotype 2) strains which have been derived from the wild-type dengue-2 strain 16681 by passaging on PDK and Vero cells and nucleic acids thereof. The invention further relates to a vaccine composition which comprises a VDV2 strain. |
| FILED | Tuesday, December 08, 2009 |
| APPL NO | 12/633459 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.720 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067608 | Beachy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Philip A. Beachy (Towson, Maryland); James K. Chen (Mountain View, California); Anssi J. Taipale (Helsinki, Finland) |
| ABSTRACT | Aromatic compounds for treating various diseases and pathologies are disclosed. The methods use of such compounds are also provided. Accordingly, the present invention makes available methods and compositions for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function. |
| FILED | Wednesday, September 29, 2004 |
| APPL NO | 10/573945 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/337 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067632 | Wender et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Paul A. Wender (Menlo Park, California); Jeffrey Warrington (Redwood City, California); Jung-Min Kee (New York, New York) |
| ABSTRACT | This invention concerns a process to convert a hydroxyl group (bold in R3C—OH) in a tigliane-type compound to a hydrogen (bold in R3C—H) to obtain deoxytigliane-type compounds or structural or functional analogs thereof. The process has wide application particularly to produce specific biologically active compounds in quantity for use as pharmaceuticals. In particular the process can be used to convert phorbol to a 12-deoxytigliane (prostrating which is a therapeutic lead for the treatment of AIDS. New compositions of matter are also disclosed. |
| FILED | Thursday, July 24, 2008 |
| APPL NO | 12/178860 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 560/129 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067936 | Garwood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Michael G. Garwood (Medina, Minnesota); Djaudat S. Idiyatullin (New Brighton, Minnesota); Curtis A. Corum (Shoreview, Minnesota); Steen Moeller (Golden Valley, Minnesota) |
| ABSTRACT | A method of magnetic resonance is provided that uses a frequency swept excitation wherein the acquired signal is a time domain signal is provided. In one embodiment, the method comprises, applying a sweeping frequency excitation and acquiring a time domain signal. The sweeping frequency excitation has a duration and is configured to sequentially excite isochromats having different resonant frequencies. Acquisition of the time domain signal is done during the duration of the sweeping frequency excitation. The time domain signal is based on evolution of the isochromats. |
| FILED | Wednesday, August 04, 2010 |
| APPL NO | 12/850508 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068649 | Green |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | SRI International, Inc. (Menlo Park, California) |
| INVENTOR(S) | Philip S. Green (Redwood City, California) |
| ABSTRACT | In a telemanipulation system for manipulating objects located in a workspace at a remote worksite by an operator from an operator's station, such as in a remote surgical system, the remote worksite having a manipulator with an end effector for manipulating an object at the workspace, such as a body cavity, a controller including a hand control at the control operator's station for remote control of the manipulator, an image capture device, such as a camera, and image output device for reproducing a viewable real-time image, the improvement wherein a position sensor associated with the image capture device senses position relative to the end effector and a processor transforms the viewable real-time image into a perspective image with correlated manipulation of the end effector by the hand controller such that the operator can manipulate the end effector and the manipulator as if viewing the workspace in true presence. Image transformation according to the invention includes translation, rotation and perspective correction. |
| FILED | Thursday, January 10, 2008 |
| APPL NO | 11/971984 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068893 | Guttman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Michael Guttman (Derwood, Maryland); Elliot R. McVeigh (Phoenix, Maryland) |
| ABSTRACT | A method of producing volume renderings from magnetic resonance image data in real time with user interactivity. The method comprises collecting raw magnetic resonance image (MRI) data representative of shapes within an image volume; transferring the raw MRI data to a computer; and continuously producing volume renderings from the raw MRI data in real time with respect to the act of collecting raw MRI data representative of shapes within the image volume. |
| FILED | Thursday, February 14, 2002 |
| APPL NO | 10/076882 |
| ART UNIT | 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068913 | Greenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert Jay Greenberg (Los Angeles, California); Mark S. Humayun (Glendale, California) |
| ABSTRACT | Present invention is a method of improving circadian rhythms in blind people by stimulation the visual neural system. Ideally a retinal prosthesis of the type used to restore vision can be used to restore normal circadian rhythms. Additionally, brightness on the prosthesis can be increased in the morning and decreased in the evening to stimulate normal Circadian rhythms. Alternatively, if a retinal prosthesis is not preferable, the retina can be stimulated externally, during the day and not at night. While such eternal stimulation can not produced artificial vision, it can stimulate normal circadian rhythms. |
| FILED | Thursday, December 01, 2005 |
| APPL NO | 11/293400 |
| ART UNIT | 3766 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068994 | Dr{hacek over (a)}ghici |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Sorin Dr{hacek over (a)}ghici (Detroit, Michigan) |
| ABSTRACT | Significance of biological pathway in disease state is predicted by (a) providing expression level data for a plurality of biomolecules differentially expressed in a disease state, compared with same biomolecules expressed in a non-diseased state: (b) determining presence probability of the biomolecules in disease state; (c) determining effect of each biomolecule from the plurality of biomolecules on the expression of different downstream biomolecules within pathway to provide perturbation factor for each biomolecule in the pathway; (d) combining statistical significance of differentially expressed biomolecules present in the disease state, with a sum of perturbation factors for all of the biomolecules, generating an impact factor; (e) calculating statistical significance of impact factor based upon determined probability of having statistical significant presence of differentially expressed biomolecules in step (b) and the sum of perturbation factors in step (c); and (f) outputting statistical significance of impact factor for the pathway relevant to the disease. |
| FILED | Friday, July 25, 2008 |
| APPL NO | 12/180303 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08065903 | Ginn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Jason R. Ginn (North Palm Beach, Florida); Zachary A. Grabe (West Palm Beach, Florida); Vanessa DeSha (West Palm Beach, Florida) |
| ABSTRACT | An energy absorber comprises at least one layer of energy absorbing material, each layer having a plurality of cells within the respective layer of energy absorbing material, wherein each layer of energy absorbing material deforms when a force applied to the at least one layer of energy absorbing material reaches a threshold force level; a fluid filling the plurality of cells in each respective layer of energy absorbing material; and a skin covering external surfaces of each respective layer of energy absorbing material to contain the fluid within the cells of the respective layer of energy absorbing material until the force applied to the energy absorbing material causes the respective layer to deform; wherein the threshold force level for each layer of energy absorbing material is based on a viscosity of the fluid in the cells of the respective layer and on a crush strength of the respective layer of energy absorbing material. |
| FILED | Thursday, July 30, 2009 |
| APPL NO | 12/512535 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/12.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066031 | Welle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Richard P. Welle (Huntington Beach, California) |
| ABSTRACT | A microfluidic device includes a substrate including multiple electro-hydraulic valves and/or electro-hydraulic pumps that each include a flow channel and one or more hydraulic control channels, actuators for controlling the electro-hydraulic valves and/or electro-hydraulic pumps, and a hydraulic pressure source operatively connected to the hydraulic control channels. |
| FILED | Monday, March 29, 2010 |
| APPL NO | 12/749350 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/828 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066088 | Asbeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Alan T. Asbeck (Stanford, California); Sangbae Kim (Stanford, California); Mark R. Cutkosky (Palo Alto, California) |
| ABSTRACT | A biologically inspired climbing device with toes and spines is provided. The device has toes capable of moving independently from each other. Each toe distinguishes a compliant linkage, which has non-compliant parts and compliant parts. Spines are distributed over each of the toes. The spines have a diameter that is less than or equal to a diameter of an asperity of a surface. The toes with spines could be arranged into one or more feet. The feet could then be organized in legs enabling the device to climb a surface in a gait pattern. The device uses low power and is quiet, leaves no traces or tracks behind, works well on smooth, rough, uneven, porous and dirty surfaces, and is able to carry and support its own body weight. |
| FILED | Friday, December 09, 2005 |
| APPL NO | 11/298306 |
| ART UNIT | 3611 — Fluid Handling and Dispensing |
| CURRENT CPC | Motor vehicles 180/8.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066227 | Keller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Composite Technology Development, Inc. (Lafayette, Colorado) |
| INVENTOR(S) | Philip N. Keller (Longmont, Colorado); Robert Taylor (Superior, Colorado); Dana Turse (Broomfield, Colorado); Larry G. Adams (Thornton, Colorado) |
| ABSTRACT | Deployable structures are disclosed having collapsible structural members that include a stowed configuration with a volume smaller than the expanded configuration. Such structures can include and/or be used for litters, bridges, support structures, solar arrays, and more. These structures can be easily transported to a new location and deployed from the stowed configuration into a larger functional structure. In some embodiments these structures can use one or more slit-tube longerons that can have two resting states: deployed and rolled. |
| FILED | Monday, February 28, 2011 |
| APPL NO | 13/036199 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/172.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066262 | Dzula, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Walter Dzula, III (Fredericksburg, Virginia); Kevin Matthew Cogley (King George, Virginia); Laura Marie Haak (Park Ridge, Illinois); Gregory Neumann Miller (Spotsylvania, Virginia); Brian Franklin Rainer (King George, Virginia); Anthony Charlie Richardson (King George, Virginia); George Russell Richardson (Norfolk, Virginia) |
| ABSTRACT | A device for opening a cylindrically bilateral filter canister, such as that houses the M98 chemical, biological, radiological filter for storage and transport. The filter canister is sealed with an epoxy-covered pull-cord that ends in an eye-loop. The device is disposed on a platform for the opening operation. The device includes a frame, first and second rollers, and a winch. The frame includes first and second support members. The first support member engages the platform and supports the second support member. The first and second rollers are disposed parallel to the platform to support the canister along its periphery. The winch includes a drum and a motor and is disposed on the frame. The drum engages the eye-loop. The motor turns said drum to receive the pull-cord from the canister. |
| FILED | Thursday, May 28, 2009 |
| APPL NO | 12/456270 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Implements or apparatus for applying pushing or pulling force 254/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066474 | Jansen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Jansen's Aircraft Systems Controls, Inc. (Tempe, Arizona) |
| INVENTOR(S) | Harvey B. Jansen (Mesa, Arizona); David K. Shields (Mesa, Arizona) |
| ABSTRACT | A variable guide vane actuator for positioning the guide vanes of a turbine engine in a hypersonic missile uses compressor exhaust to drive a linked, floating piston assembly that is coupled to the guide vanes. The relatively low pressure compressor exhaust is metered by a valve to drive the piston arrangement to accurately position the guide vanes in proportion to the input control signal. Reliability and accuracy gains are achieved by inhibiting the effects of vibration and thermal distortion through the elimination of piston/bore contact, the use of a rigid, cantilevered mounting arrangement and cooling with the pre-combusted liquid fuel. |
| FILED | Friday, June 15, 2007 |
| APPL NO | 11/764149 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066831 | Gangopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Shubhra Gangopadhyay (Columbia, Missouri); Steven Apperson (Columbia, Missouri); Keshab Gangopadhyay (Columbia, Missouri); Andrey Bezmelnitsyn (Columbia, Missouri); Rajagopalan Thiruvengadathan (Columbia, Missouri); Michael Kraus (Columbia, Missouri); Rajesh Shende (Rapid City, South Dakota); Maruf Hossain (Columbia, Missouri); Senthil Subramanian (Poway, California); Shantanu Bhattacharya (Columbia, Missouri); Yuangang Gao (Boulder, Colorado) |
| ABSTRACT | A method of generating power uses a nanoenergetic material. The nanoenergetic material comprising thermite is obtained and deposited on a substrate. An igniter is placed on the nanoenergetic material. When power is desired, the nanoenergetic material is ignited. A transducer receives thermal, sonic, magnetic, optic and/or mechanical energy from combustion of the nanoenergetic material and converts it into electrical energy. Preferably, the transducer is a thermoelectric, piezoelectric or magneto device. Preferably, multiple transducers are integrated in one power generators to maximize the power from nanoenergetic thermites. |
| FILED | Friday, October 27, 2006 |
| APPL NO | 12/083985 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066855 | Suh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Dong-Seok Suh (Seoul, South Korea); Ray Henry Baughman (Dallas, Texas); Anvar Abdulahadovic Zakhidov (Richardson, Texas) |
| ABSTRACT | In some embodiments, the present invention is directed to processes for the combination of injecting charge in a material electrochemically via non-faradaic (double-layer) charging, and retaining this charge and associated desirable properties changes when the electrolyte is removed. The present invention is also directed to compositions and applications using material property changes that are induced electrochemically by double-layer charging and retained during subsequent electrolyte removal. In some embodiments, the present invention provides reversible processes for electrochemically injecting charge into material that is not in direct contact with an electrolyte. Additionally, in some embodiments, the present invention is directed to devices and other material applications that use properties changes resulting from reversible electrochemical charge injection in the absence of an electrolyte. |
| FILED | Friday, October 13, 2006 |
| APPL NO | 11/580397 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067184 | Schwoebel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric D. Schwoebel (Woburn, Massachusetts); James D. Harper (Boston, Massachusetts); Martha S. Petrovick (Barre, Massachusetts); Frances E. Nargi (Littleton, Massachusetts); Todd H. Rider (Littleton, Massachusetts); Kristine E. Hogan (Danvers, Massachusetts); Richard H. Mathews (Chelmsford, Massachusetts); Joseph Lacirignola (Beverly, Massachusetts); Mark Hennessy (Cambridge, Massachusetts); Trina R. Vian (Groton, Massachusetts); Rose M. Joseph (Westford, Massachusetts); Raymond S. Uttaro (Lexington, Massachusetts); Shaun Berry (Chelmsford, Massachusetts); Bernadette Johnson (Hollis, New Hampshire); Mark A. Hollis (Concord, Massachusetts) |
| ABSTRACT | The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples. |
| FILED | Thursday, July 03, 2008 |
| APPL NO | 12/217471 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067202 | Ulrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert G. Ulrich (Frederick, Maryland); Mark A. Olson (Gaithersburg, Maryland); Sina Bavari (Dillsburg, Pennsylvania) |
| ABSTRACT | The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described. |
| FILED | Wednesday, May 07, 2008 |
| APPL NO | 12/151497 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067230 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Elaine Lynette Wilson (New York, New York); Patricia Burger (Bloubergstrand, South Africa) |
| ABSTRACT | Prostatic stem cells have been isolated. Benign prostatic hyperplasia and other proliferative diseases of the prostate may arise in prostatic stem cells. The prostatic stem cells are used as a research tool for studying cancer and other proliferative diseases of the prostate, and for developing diagnostics and therapeutics for proliferative diseases of the prostate. Antibodies to the antigens expressed by prostatic stem cells can be used as therapeutics or diagnostics or can be used to deliver therapeutic or diagnostic agents directly to the prostatic stem cells. |
| FILED | Tuesday, May 10, 2005 |
| APPL NO | 11/596351 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067377 | Arap et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Regents of the University of Texas systems (Austin, Texas) |
| INVENTOR(S) | Wadih Arap (Houston, Texas); Renata Pasqualini (Houston, Texas) |
| ABSTRACT | The present invention concerns methods and compositions for in vivo and in vitro targeting. A large number of targeting peptides directed towards human organs, tissues or cell types are disclosed. The peptides are of use for targeted delivery of therapeutic agents, including but not limited to gene therapy vectors. A novel class of gene therapy vectors is disclosed. Certain of the disclosed peptides have therapeutic use for inhibiting angiogenesis, inhibiting tumor growth, inducing apoptosis, inhibiting pregnancy or inducing weight loss. Methods of identifying novel targeting peptides in humans, as well as identifying endogenous receptor-ligand pairs are disclosed. Methods of identifying novel infectious agents that are causal for human disease states are also disclosed. A novel mechanism for inducing apoptosis is further disclosed. |
| FILED | Tuesday, May 29, 2007 |
| APPL NO | 11/754761 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067724 | Hochberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Michael J. Hochberg (Seattle, Washington); Tom Baehr-Jones (Seattle, Washington) |
| ABSTRACT | An all-optical integrated photonic clock, systems employing the same, and methods of making and using the same. Illustrative examples are provided based on silicon semiconductor technology that employs rectangular waveguides fabricated on SOI wafers. In some embodiments, the clock can provide an optical timing signal. In some embodiments, the clock can provide a jitter-free electrical signal derived from the clock by use of a high speed photodetector. |
| FILED | Wednesday, May 27, 2009 |
| APPL NO | 12/455008 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/227.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067742 | Winso et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Space Micro Inc. (San Diego, California) |
| INVENTOR(S) | James H Winso (Escondido, California); Michael D Fennell (San Diego, California) |
| ABSTRACT | An apparatus for detecting and determining a source azimuth for gamma radiation includes at least two scintillation crystals at angular offsets and directed toward a common plane of detection, photodetectors adjacent to each of the scintillation crystals for converting the light response of the scintillation crystals into distinct electrical signals, and a digital processing system configured to analyze spectral data from each electrical signal produced for each crystal. The digital processing system monitors a finite number of spectral windows corresponding to a selected set of radioisotopes, and uses one or more of the electrical signals to determine a signal intensity and a likely source azimuth for a detected radioisotope in the plane of detection. Another scintillation crystal directed outside of the common plane of detection may be used for three-dimensional detection. Related methods for detection and location of gamma ray sources are discussed. |
| FILED | Tuesday, June 12, 2007 |
| APPL NO | 11/808648 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067875 | Blackburn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael R. Blackburn (Encinitas, California); Wayne C. McGinnis (San Diego, California) |
| ABSTRACT | An artificial neuromuscular unit (ANMU) network comprising: a plurality of ANMUs, wherein each ANMU comprises an electroactive polymer (EAP) actuator layer and a uniquely addressable EAP logic layer coupled to the actuator layer; a plurality of inert, non-ion-conducting and non-charge-conducting interfaces mechanically coupled between the ANMUs such that the actuator layer of each ANMU is insulated from the actuator layers and logic layers of the other ANMUs; an EAP common conductor layer coupled to the logic layer of each ANMU such that the logic layer of each ANMU is interposed between the common conductor layer and the corresponding actuator layer; and wherein the logic layer of each ANMU is configured to control the transfer of energy to and from the common conductor layer and the corresponding actuator layer. |
| FILED | Monday, April 13, 2009 |
| APPL NO | 12/422697 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068062 | Webb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | GBS Positioner, LLC. (Nashua, New Hampshire); AntennaSys, Inc. (Pelham, New Hampshire) |
| INVENTOR(S) | Spencer Webb (Pelham, New Hampshire); David Martin (Nashua, New Hampshire) |
| ABSTRACT | A low power, lightweight, collapsible and rugged antenna positioner for use in communicating with geostationary, geosynchronous and low earth orbit satellite. By collapsing, invention may be easily carried or shipped in a compact container. May be used in remote locations with simple or automated setup and orientation. Azimuth is adjusted by rotating an antenna in relation to a positioner base and elevation is adjusted by rotating an elevation motor coupled with the antenna. Manual orientation of antenna for linear polarized satellites yields lower weight and power usage. Updates ephemeris or TLE data via satellite. Algorithms used for search including Clarke Belt fallback, transponder/beacon searching switch, azimuth priority searching and tracking including uneven re-peak scheduling yield lower power usage. Orientation aid via user interface allows for smaller azimuth motor, simplifies wiring and lowers weight. Tilt compensation, bump detection and failure contingency provide robustness. |
| FILED | Friday, January 07, 2011 |
| APPL NO | 12/986891 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Communications: Radio wave antennas 343/766 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068066 | Perkins, III |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Jersey) |
| INVENTOR(S) | Thomas O Perkins, III (Bedford, New Hampshire) |
| ABSTRACT | An X-band, crossed dipole turnstile antenna configured to be omni-directional with horizontal polarization is disclosed. It comprises a set of two dipole antennas aligned at right angles to each other attached to a common 50 ohm coaxial feedpoint and fed 90 degrees out-of-phase. The antenna pattern is nearly omnidirectional in the horizontal plane. The antenna can be used generally in microwave communications including Digital Radio Frequency Tags (DRaFTs) communicating with airborne and satellite platforms. |
| FILED | Monday, August 25, 2008 |
| APPL NO | 12/197456 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Communications: Radio wave antennas 343/797 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068278 | Janson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Siegfried W. Janson (Redondo Beach, California); Margaret Abraham (Portola Valley, California) |
| ABSTRACT | Photostructurable glass and ceramic materials in slabs are processed into pixelized screens having opaque baffles therein for defining therebetween light pipes in the material through which pixel light is passed and directed with limited fields of view and for stereoscopic viewing, the screens being made using various manufacturing processes included focused UV light exposure and baking of the photostructurable material. |
| FILED | Wednesday, September 19, 2007 |
| APPL NO | 11/901910 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/472 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068426 | Sundararajan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jay Kumar Sundararajan (Cambridge, Massachusetts); Devavrat Shah (Newton, Massachusetts); Muriel Medard (Belmont, Massachusetts); Parastoo Sadeghi (Gungahlin, Australia) |
| ABSTRACT | A method, apparatus and computer program product for feedback-based online network coding is presented. In one embodiment, a transmitting node determines a linear combination of packets to transmit from a transmit queue. The transmitting node transmits the linear combination of packets. The transmitting node determines whether a packet can be removed from the transmit queue, wherein when a determination is made that a packet can be removed from the transmit queue then removing the packet from the transmit queue, and when a determination is made that a packet cannot be removed from the transmit queue then refraining from removing the packet from the transmit queue. |
| FILED | Friday, May 29, 2009 |
| APPL NO | 12/474738 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/235 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068435 | Agarwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Viasat, Inc. (Carlsbad, California) |
| INVENTOR(S) | Anil Agarwal (North Potomac, Maryland); Mark Miller (Vista, California) |
| ABSTRACT | A communication system transmitting signals over a network using a transmission waveform in which a plurality of data packets are transmitted in a payload field of a transmission frame, the system includes a transmitter, which has a transmitting portion that sends information including user data in the data packets and a user data rate portion that dynamically changes the data rate of the user data to the highest rate possible for current link conditions by changing the waveform. The communication system also includes a receiver, which has a receiving portion that receives the information data packets and a reconfiguration portion that reconfigures the receiving portion based on the waveform parameters. |
| FILED | Friday, August 03, 2007 |
| APPL NO | 11/882647 |
| ART UNIT | 2475 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/249 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068740 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Mark W. Roberts (San Diego, California); Markham E. Lasher (La Jolla, California) |
| ABSTRACT | In various embodiments, a secure optical communication system is disclosed. Such a system may include a photon-pair generation circuit configured to generate pairs of photons with each photon pair including a first-channel photon and a second-channel photon, a transmitting circuit configured to receive first-channel photons, and modulate the first-channel photons according to a stream of data using a first optical circulator to produce first-modulated photons, and a receiving circuit configured to receive second-channel photons, pass the second-channel photons through a complementary optical circulator to produce second modulated photons, and detect relative timing between the first-modulated photons and the second modulated photons to recover the stream of data. |
| FILED | Tuesday, July 29, 2008 |
| APPL NO | 12/182106 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Optical communications 398/140 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08069015 | Chugg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | National Science Foundation (Arlington, Virginia) |
| INVENTOR(S) | Keith M. Chugg (La Canada, California); On Wa Yeung (Los Angeles, California) |
| ABSTRACT | Systems and methods for signal analysis are described. The method can include digitizing a signal modulated by a pseudo noise (PN) sequence, dividing the digitized signal into a plurality of sample blocks, and estimating a PN phase embedded in a sample block of the plurality of sample blocks using an iterative message passing algorithm (iMPA) executed on a redundant graphical model. |
| FILED | Friday, April 20, 2007 |
| APPL NO | 11/738438 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08069127 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | 21 CT, Inc. (Austin, Texas) |
| INVENTOR(S) | Darrin Taylor (Austin, Texas); Lee Alford (Austin, Texas) |
| ABSTRACT | A method and system for solving an optimization problem comprising a plurality of dynamic constraints. A genetic algorithm is used to iteratively generate potential solutions to the problem. A constraint graph is used to model the plurality of dynamic constraints, and any potential solution that does not correspond to a connected subgraph of the constraint graph is infeasible and discarded. Real-time changes in dynamic constraints are incorporated by modification of the constraint graph between iterations of the genetic algorithm. An exemplary embodiment comprising the scheduling of air missions is presented. |
| FILED | Thursday, April 26, 2007 |
| APPL NO | 11/789917 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08065810 | Rempe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Joy L. Rempe (Idaho Falls, Idaho); Darrell L. Knudson (Firth, Idaho); Joshua E. Daw (Idaho Falls, Idaho); Keith G. Condie (Idaho Falls, Idaho); Carl M. Stoots (Idaho Falls, Idaho) |
| ABSTRACT | Elongation measurement apparatuses and systems comprise at least two Linear Variable Differential Transformers (LVDTs) with a push rod coupled to each of the at least two LVDTs at one longitudinal end thereof. At least one push rod extends to a base and is coupled thereto at an opposing longitudinal end, and at least one other push rod extends to a location spaced apart from the base and is configured to receive a sample between an opposing longitudinal end of the at least one other push rod and the base. Nuclear reactors comprising such apparatuses and systems and methods of measuring elongation of a material are also disclosed. |
| FILED | Tuesday, April 07, 2009 |
| APPL NO | 12/419916 |
| ART UNIT | 2841 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Geometrical instruments 033/502 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08065844 | Botkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sunpower Corporation (San Jose, California) |
| INVENTOR(S) | Jonathan Botkin (El Cerrito, California); Simon Graves (Berkeley, California); Matt Danning (Oakland, California) |
| ABSTRACT | A photovoltaic (PV) module assembly including a PV module and a ballast tray. The PV module includes a PV device and a frame. A PV laminate is assembled to the frame, and the frame includes an arm. The ballast tray is adapted for containing ballast and is removably associated with the PV module in a ballasting state where the tray is vertically under the PV laminate and vertically over the arm to impede overt displacement of the PV module. The PV module assembly can be installed to a flat commercial rooftop, with the PV module and the ballast tray both resting upon the rooftop. In some embodiments, the ballasting state includes corresponding surfaces of the arm and the tray being spaced from one another under normal (low or no wind) conditions, such that the frame is not continuously subjected to a weight of the tray. |
| FILED | Friday, June 26, 2009 |
| APPL NO | 12/492640 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Static structures 052/173.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08065878 | Vuk |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Deere and Company (Moline, Illinois) |
| INVENTOR(S) | Carl T. Vuk (Denver, Iowa) |
| ABSTRACT | An internal combustion engine having a reciprocating multi cylinder internal combustion engine with multiple valves. At least a pair of exhaust valves are provided and each supply a separate power extraction device. The first exhaust valves connect to a power turbine used to provide additional power to the engine either mechanically or electrically. The flow path from these exhaust valves is smaller in area and volume than a second flow path which is used to deliver products of combustion to a turbocharger turbine. The timing of the exhaust valve events is controlled to produce a higher grade of energy to the power turbine and enhance the ability to extract power from the combustion process. |
| FILED | Monday, March 10, 2008 |
| APPL NO | 12/045390 |
| ART UNIT | 3748 — Static Structures, Supports and Furniture |
| CURRENT CPC | Power plants 060/612 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08065904 | Allendorf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Livermore, California) |
| INVENTOR(S) | Mark D. Allendorf (Pleasanton, California); Peter J. Hesketh (Atlanta, Georgia) |
| ABSTRACT | We describe the use of coordination polymers (CP) as coatings on microcantilevers for the detection of chemical analytes. CP exhibit changes in unit cell parameters upon adsorption of analytes, which will induce a stress in a static microcantilever upon which a CP layer is deposited. We also describe fabrication methods for depositing CP layers on surfaces. |
| FILED | Thursday, June 12, 2008 |
| APPL NO | 12/137635 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/31.60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066478 | Shih et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Tom I-P Shih (Ames, Iowa); Sangkwon Na (Ames, Iowa) |
| ABSTRACT | A system for cooling includes a surface to be cooled, at least one film-cooling hole within the surface for allowing a film cooling jet of coolant to reach the surface, each of the at least one film-cooling hole having a diameter and at least two spaced apart flow-aligned blockers positioned downstream of the at least one-film cooling hole, each of the flow-aligned blockers extending upwardly from the surface to assist in preventing hot-gas entrainment and increasing adiabatic effectiveness by confining coolant flow downstream of the at least one film-cooling hole between the blockers. |
| FILED | Wednesday, October 17, 2007 |
| APPL NO | 11/975012 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066789 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Southern Company (Birmingham, Alabama) |
| INVENTOR(S) | Guohai Liu (Birmingham, Alabama); Wan Wang Peng (Birmingham, Alabama); Pannalal Vimalchand (Birmingham, Alabama) |
| ABSTRACT | A system for depressurizing and cooling a high pressure, high temperature fine solid particles stream having entrained gas therein. In one aspect, the system has an apparatus for cooling the high pressure, high temperature fine solid particles stream having entrained gas therein and a pressure letdown device for depressurization by separating the cooled fine solid particles from a portion of the fine solid particles stream having entrained gas therein, resulting in a lower temperature, lower pressure outlet of solid particles for disposal or handling by downstream equipment. |
| FILED | Monday, April 20, 2009 |
| APPL NO | 12/426669 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation 055/474 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066852 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Dali Yang (Los Alamos, New Mexico); David Devlin (Santa Fe, New Mexico); Robert S. Barbero (Santa Cruz, New Mexico); Martin E. Carrera (Naperville, Illinois); Craig W. Colling (Warrenville, Illinois) |
| ABSTRACT | Light hydrocarbon enrichment is accomplished using a vertically oriented distillation column having a plurality of vertically oriented, nonselective micro/mesoporous hollow fibers. Vapor having, for example, both propylene and propane is sent upward through the distillation column in between the hollow fibers. Vapor exits neat the top of the column and is condensed to form a liquid phase that is directed back downward through the lumen of the hollow fibers. As vapor continues to ascend and liquid continues to countercurrently descend, the liquid at the bottom of the column becomes enriched in a higher boiling point, light hydrocarbon (propane, for example) and the vapor at the top becomes enriched in a lower boiling point light hydrocarbon (propylene, for example). The hollow fiber becomes wetted with liquid during the process. |
| FILED | Wednesday, June 30, 2010 |
| APPL NO | 12/827981 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Distillation: Processes, separatory 23/39 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066861 | Park |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Jong-Hee Park (Clarendon Hills, Illinois) |
| ABSTRACT | A method for producing metal powder is provided the comprising supplying a molten bath containing a reducing agent, contacting a metal oxide with the molten bath for a time and at a temperature sufficient to reduce the metal in the metal oxide to elemental metal and produce free oxygen; and isolating the elemental metal from the molten bath. |
| FILED | Thursday, February 14, 2008 |
| APPL NO | 12/031146 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/43 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066968 | Mao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Carnegie Institution of Washington (Washington, District of Columbia) |
| INVENTOR(S) | Ho-kwang Mao (Washington, District of Columbia); Wendy L. Mao (Washington, District of Columbia) |
| ABSTRACT | A novel molecular alloy of O2 and H2 and a method of producing such a molecular alloy are provided. When subjected to high pressure and extensive x-radiation, H2O molecules cleaved, forming O—O and H—H bonds. In the method of the present invention, the O and H framework in ice VII was converted into a molecular alloy of O2 and H2. X-ray diffraction, x-ray Raman scattering, and optical Raman spectroscopy demonstrate that this crystalline solid differs from previously known phases. |
| FILED | Friday, October 24, 2008 |
| APPL NO | 12/257537 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/579 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067053 | Laskin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Julia Laskin (Richland, Washington); Peng Wang (Billerica, Massachusetts) |
| ABSTRACT | Disclosed is a method for selective chemical binding and immobilization of macromolecules on solid supports in conjunction with self-assembled monolayer (SAM) surfaces. Immobilization involves selective binding of peptides and other macromolecules to SAM surfaces using reactive landing (RL) of mass-selected, gas phase ions. SAM surfaces provide a simple and convenient platform for tailoring chemical properties of a variety of substrates. The invention finds applications in biochemistry ranging from characterization of molecular recognition events at the amino acid level and identification of biologically active motifs in proteins, to development of novel biosensors and substrates for stimulated protein and cell adhesion. |
| FILED | Friday, May 09, 2008 |
| APPL NO | 12/151945 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Coating processes 427/2.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067541 | Bradbury et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Andrew M. Bradbury (Santa Fe, New Mexico); Geoffrey S. Waldo (Santa Fe, New Mexico); Csaba Kiss (Los Alamos, New Mexico) |
| ABSTRACT | Thermostable fluorescent proteins (TSFPs), methods for generating these and other stability-enhanced proteins, polynucleotides encoding such proteins, and assays and method for using the TSFPs and TSFP-encoding nucleic acid molecules are provided. The TSFPs of the invention show extremely enhanced levels of stability and thermotolerance. In one case, for example, a TSFP of the invention is so stable it can be heated to 99° C. for short periods of time without denaturing, and retains 85% of its fluorescence when heated to 80° C. for several minutes. The invention also provides a method for generating stability-enhanced variants of a protein, including but not limited to fluorescent proteins. |
| FILED | Tuesday, February 08, 2011 |
| APPL NO | 13/023421 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067610 | Schrodi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yann Schrodi (Agoura Hills, California) |
| ABSTRACT | This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) wherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry. |
| FILED | Friday, July 13, 2007 |
| APPL NO | 11/879029 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067687 | Wanlass |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Mark W. Wanlass (Golden, Colorado) |
| ABSTRACT | A monolithic, multi-bandgap, tandem solar photovoltaic converter has at least one, and preferably at least two, subcells grown lattice-matched on a substrate with a bandgap in medium to high energy portions of the solar spectrum and at least one subcell grown lattice-mismatched to the substrate with a bandgap in the low energy portion of the solar spectrum, for example, about 1 eV. |
| FILED | Thursday, December 30, 2004 |
| APPL NO | 11/027156 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/249 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067730 | Vertes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Akos Vertes (Reston, Virginia); Peter Nemes (Silver Spring, Maryland) |
| ABSTRACT | The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation (LA) with electrospray ionization (ESI). |
| FILED | Friday, July 18, 2008 |
| APPL NO | 12/176324 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068522 | Barty |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Christopher P. J. Barty (Hayward, California) |
| ABSTRACT | A grating pulse compressor configuration is introduced for increasing the optical dispersion for a given footprint and to make practical the application for chirped pulse amplification (CPA) to quasi-narrow bandwidth materials, such as Nd:YAG. The grating configurations often use cascaded pairs of gratings to increase angular dispersion an order of magnitude or more. Increased angular dispersion allows for decreased grating separation and a smaller compressor footprint. |
| FILED | Thursday, June 23, 2005 |
| APPL NO | 11/166988 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068984 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Stephen F. Smith (Loudon, Tennessee); James A. Moore (Powell, Tennessee) |
| ABSTRACT | Methods and apparatus are described for a navigation system. A method includes providing a global positioning system fix having a plurality of tracking parameters; providing a theater positioning system fix; monitoring the plurality of tracking parameters for predetermined conditions; and, when the predetermined conditions are met, sending a notifying signal and switching to the theater positioning system fix as a primary fix. An apparatus includes a system controller; a global positioning system receiver coupled to the system controller; a radio frequency locating receiver coupled to the system controller; and an operator interface coupled to the system controller. |
| FILED | Tuesday, October 17, 2006 |
| APPL NO | 11/583373 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/213 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08066834 | Petersen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Eric Petersen (Orlando, Florida); Jennifer Small (Dunlap, Illinois); Metthew Stephens (Ft. Pierce, Florida); Jason Arvanetes (Crestview, Florida); Sudipta Seal (Oviedo, Florida); Sameer Deshpande (Orlando, Florida) |
| ABSTRACT | Adding nanoparticles as a catalyst to solid propellant fuel to increase and enhance burn rates of the fuel by up to 10 times or more and/or modifying the pressure index. A preferred embodiment uses TiO2 nanoparticles mixed with a solid propellant fuel, where the nanoparticles are approximately 2% or less of total propellant mixture. The high surface to volume ratio of the nanoparticles improve the performance of the solid propellant fuel. |
| FILED | Thursday, August 03, 2006 |
| APPL NO | 11/498577 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/76 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066914 | Hu |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Akron (Akron, Ohio) |
| INVENTOR(S) | Jun Hu (Fairlawn, Ohio) |
| ABSTRACT | 7-ethynyl-2,4,9-trithiaadamantane and related methods are presented. Manufacturing 7-ethynyl-2,4,9-trithiaadamantane includes the steps of: (1) reducing alkyl 2,4,9-trithiaadamantane-7-carboxylate to produce 7-hydroxymethyl-2,4,9-trithiaadamantane; (2) oxidizing 7-hydroxymethyl-2,4,9-trithiaadamantane to produces 7-carbonyl-2,4,9-trithiaadamantane; and (3) reacting 7-carbonyl-2,4,9-trithiaadamantane with Ohira-Bestmann reagent to produces 7-ethynyl-2,4,9-trithiaadamantane. Molecular wires having 2,4,9-trithiaadamantane surface anchors are also disclosed. |
| FILED | Friday, October 31, 2008 |
| APPL NO | 12/262871 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Compositions 252/519.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066964 | Prud'Homme et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Robert K. Prud'Homme (Lawrenceville, New Jersey); Ilhan A. Aksay (Princeton, New Jersey); Ahmed Abdala (Suez, Egypt) |
| ABSTRACT | A modified graphite oxide material contains a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g, wherein the thermally exfoliated graphite oxide displays no signature of the original graphite and/or graphite oxide, as determined by X-ray diffraction. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791190 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/415.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067078 | Espinosa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Horacio Dante Espinosa (Winnetka, Illinois); François Barthelat (Montréal, Canada) |
| ABSTRACT | The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial and clinical applications, including aeronautics (aircraft skin), the defense industry (armor materials); orthopedics and medical devices (tough, biocompatible coatings on prostheses) and micro-electro-mechanical systems (MEMS; increased reliability for critical components). |
| FILED | Tuesday, November 13, 2007 |
| APPL NO | 11/985115 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067521 | Kennedy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Joseph P. Kennedy (Akron, Ohio); Gabor Erdodi (Stow, Ohio) |
| ABSTRACT | The present invention relates to the production of amphiphilic copolymer networks or co-networks that are both hydrophobic and hydrophilic, the copolymer networks comprise polyalkylene glycol segments and disubstituted polysiloxane segments. Furthermore, the present invention relates to products and/or films made from the amphiphilic copolymer networks or co-networks produced in accordance with the synthesis methods of the present invention. In one embodiment, amphiphilic networks or co-networks are synthesized using functional multiblock co-polymers according to the formula (AY)x(BY)y, where A represents an alkylene glycol polymer having n repeating alkylene glycol units, B represents a disubstituted siloxane polymer having m repeating siloxane units, and Y represents a molecule (e.g., a silane) that functions both as a chain extender and a crosslinker. |
| FILED | Thursday, July 28, 2005 |
| APPL NO | 11/572826 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067730 | Vertes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Akos Vertes (Reston, Virginia); Peter Nemes (Silver Spring, Maryland) |
| ABSTRACT | The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation (LA) with electrospray ionization (ESI). |
| FILED | Friday, July 18, 2008 |
| APPL NO | 12/176324 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068426 | Sundararajan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jay Kumar Sundararajan (Cambridge, Massachusetts); Devavrat Shah (Newton, Massachusetts); Muriel Medard (Belmont, Massachusetts); Parastoo Sadeghi (Gungahlin, Australia) |
| ABSTRACT | A method, apparatus and computer program product for feedback-based online network coding is presented. In one embodiment, a transmitting node determines a linear combination of packets to transmit from a transmit queue. The transmitting node transmits the linear combination of packets. The transmitting node determines whether a packet can be removed from the transmit queue, wherein when a determination is made that a packet can be removed from the transmit queue then removing the packet from the transmit queue, and when a determination is made that a packet cannot be removed from the transmit queue then refraining from removing the packet from the transmit queue. |
| FILED | Friday, May 29, 2009 |
| APPL NO | 12/474738 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/235 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068898 | Mycek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Mary-Ann Mycek (Ann Arbor, Michigan); Ethan Dmitrovsky (Hanover, New Hampshire); Jonathan Pitts (Westford, Massachusetts) |
| ABSTRACT | This invention relates to method and apparatus for collection of the complete fluorescence emission spectrum and the transient decay of a selected spectral band simultaneously with data acquisition times of less that one second. This invention is useful for studying human tissues and cells in vivo. |
| FILED | Thursday, February 28, 2002 |
| APPL NO | 10/469021 |
| ART UNIT | 3768 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Surgery 6/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068994 | Dr{hacek over (a)}ghici |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Sorin Dr{hacek over (a)}ghici (Detroit, Michigan) |
| ABSTRACT | Significance of biological pathway in disease state is predicted by (a) providing expression level data for a plurality of biomolecules differentially expressed in a disease state, compared with same biomolecules expressed in a non-diseased state: (b) determining presence probability of the biomolecules in disease state; (c) determining effect of each biomolecule from the plurality of biomolecules on the expression of different downstream biomolecules within pathway to provide perturbation factor for each biomolecule in the pathway; (d) combining statistical significance of differentially expressed biomolecules present in the disease state, with a sum of perturbation factors for all of the biomolecules, generating an impact factor; (e) calculating statistical significance of impact factor based upon determined probability of having statistical significant presence of differentially expressed biomolecules in step (b) and the sum of perturbation factors in step (c); and (f) outputting statistical significance of impact factor for the pathway relevant to the disease. |
| FILED | Friday, July 25, 2008 |
| APPL NO | 12/180303 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08069015 | Chugg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | National Science Foundation (Arlington, Virginia) |
| INVENTOR(S) | Keith M. Chugg (La Canada, California); On Wa Yeung (Los Angeles, California) |
| ABSTRACT | Systems and methods for signal analysis are described. The method can include digitizing a signal modulated by a pseudo noise (PN) sequence, dividing the digitized signal into a plurality of sample blocks, and estimating a PN phase embedded in a sample block of the plurality of sample blocks using an iterative message passing algorithm (iMPA) executed on a redundant graphical model. |
| FILED | Friday, April 20, 2007 |
| APPL NO | 11/738438 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08066796 | Gustafson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Orbital Technologies Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Robert J. Gustafson (Cross Plains, Wisconsin); Marty A. Gustafson (Cross Plains, Wisconsin); Brant C. White (Madison, Wisconsin) |
| ABSTRACT | A method of creating simulated agglutinate particles by applying a heat source sufficient to partially melt a raw material is provided. The raw material is preferably any lunar soil simulant, crushed mineral, mixture of crushed minerals, or similar material, and the heat source creates localized heating of the raw material. |
| FILED | Tuesday, January 22, 2008 |
| APPL NO | 12/017681 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/345 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066964 | Prud'Homme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Robert K. Prud'Homme (Lawrenceville, New Jersey); Ilhan A. Aksay (Princeton, New Jersey); Ahmed Abdala (Suez, Egypt) |
| ABSTRACT | A modified graphite oxide material contains a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g, wherein the thermally exfoliated graphite oxide displays no signature of the original graphite and/or graphite oxide, as determined by X-ray diffraction. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791190 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/415.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067478 | Meador et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Mary Ann B. Meador (Strongsville, Ohio); Lynn A. Capadona (North Ridgeville, Ohio) |
| ABSTRACT | Process for preparing polymer-reinforced silica aerogels which comprises a one-pot reaction of at least one alkoxy silane in the presence of effective amounts of a polymer precursor to obtain a silica reaction product, the reaction product is gelled and subsequently subjected to conditions that promotes polymerization of the precursor and then supercritically dried to obtain the polymer-reinforced monolithic silica aerogels. |
| FILED | Thursday, October 19, 2006 |
| APPL NO | 11/582693 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067909 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Donald R. Davis (Brighton, Michigan); Nicolaus A Radford (Houston, Texas); Frank Noble Permenter (Webster, Texas); Adam H Parsons (Houston, Texas); Joshua S Mehling (League City, Texas) |
| ABSTRACT | An electromagnetic braking system and method is provided for selectively braking a motor using an electromagnetic brake having an electromagnet, a permanent magnet, a rotor assembly, and a brake pad. The brake assembly applies when the electromagnet is de-energized and releases when the electromagnet is energized. When applied the permanent magnet moves the brake pad into frictional engagement with a housing, and when released the electromagnet cancels the flux of the permanent magnet to allow a leaf spring to move the brake pad away from the housing. A controller has a DC/DC converter for converting a main bus voltage to a lower braking voltage based on certain parameters. The converter utilizes pulse-width modulation (PWM) to regulate the braking voltage. A calibrated gap is defined between the brake pad and permanent magnet when the brake assembly is released, and may be dynamically modified via the controller. |
| FILED | Friday, May 29, 2009 |
| APPL NO | 12/474430 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Motive power systems 318/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068216 | Caldwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Ophir Corporation (Littleton, Colorado) |
| INVENTOR(S) | Loren M. Caldwell (Fort Collins, Colorado); Shoou-Yu Tang (Fort Collins, Colorado); Martin J. O'Brien (Conifer, Colorado) |
| ABSTRACT | A method for remotely sensing air outside a moving aircraft includes generating laser radiation within a swept frequency range. A portion of the laser radiation is projected from the aircraft into the air to induce scattered laser radiation. Filtered scattered laser radiation, filtered laser radiation, and unfiltered laser radiation are detected. At least one actual ratio is determined from data corresponding to the filtered scattered laser radiation and the unfiltered laser radiation. One or more air parameters are determined by correlating the actual ratio to at least one reference ratio. |
| FILED | Monday, November 10, 2008 |
| APPL NO | 12/268072 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optics: Measuring and testing 356/28.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068322 | Bingel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Thomas Bingel (Indian Rocks Beach, Florida); Deanne Tran-Vo (Palm Harbor, Florida) |
| ABSTRACT | Electronic circuit breakers and systems for isolating a load from a power-supply unit are provided. One electronic circuit breaker includes a current sensor, a switching element coupled to the current sensor, and a switch controller coupled to the current sensor and the switching element. The switch controller is powered by the power-supply unit and is configured to switch OFF the switching element when the current sensor detects an amount of current from the power-supply unit greater than a predetermined amount. An electronic system includes a power-supply unit, a load, and the above-referenced electronic circuit breaker coupled to the power-supply unit and the load. |
| FILED | Thursday, July 31, 2008 |
| APPL NO | 12/183868 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068556 | Bishop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | LJT and Associates, Inc. (Columbia, Maryland) |
| INVENTOR(S) | James W. Bishop (Ellicott City, Maryland); Nazrul H. Mohd Zaki (Columbia, Maryland); David Childress Newman (Salisbury, Maryland); Steven N. Bundick (Pocomoke City, Maryland) |
| ABSTRACT | A flexible, reconfigurable, power efficient transmitter device and method is provided. In one embodiment, the method includes receiving outbound data and determining a mode of operation. When operating in a first mode the method may include modulation mapping the outbound data according a modulation scheme to provide first modulation mapped digital data, converting the first modulation mapped digital data to an analog signal that comprises an intermediate frequency (IF) analog signal, upconverting the IF analog signal to produce a first modulated radio frequency (RF) signal based on a local oscillator signal, amplifying the first RF modulated signal to produce a first RF output signal, and outputting the first RF output signal via an isolator. In a second mode of operation method may include modulation mapping the outbound data according a modulation scheme to provide second modulation mapped digital data, converting the second modulation mapped digital data to a first digital baseband signal, conditioning the first digital baseband signal to provide a first analog baseband signal, modulating one or more carriers with the first analog baseband signal to produce a second modulated RF signal based on a local oscillator signal, amplifying the second RF modulated signal to produce a second RF output signal, and outputting the second RF output signal via the isolator. The digital baseband signal may comprise an in-phase (I) digital baseband signal and a quadrature (Q) baseband signal. |
| FILED | Thursday, June 26, 2008 |
| APPL NO | 12/147100 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08069001 | Gorbunov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| INVENTOR(S) | Sergey Gorbunov (Santa Clara, California); Edward R. Martinez (San Jose, California); James B. Scott (Santa Clara, California); Tomomi Oishi (Mountain View, California); Johnny Fu (San Leandro, California); Joseph G. Mach (Santa Clara, California); Jose B. Santos (Milpitas, California) |
| ABSTRACT | An isotherm sensor tracks space vehicle temperatures by a thermal protection system (TPS) material during vehicle re-entry as a function of time, and surface recession through calibration, calculation, analysis and exposed surface modeling. Sensor design includes: two resistive conductors, wound around a tube, with a first end of each conductor connected to a constant current source, and second ends electrically insulated from each other by a selected material that becomes an electrically conductive char at higher temperatures to thereby complete an electrical circuit. The sensor conductors become shorter as ablation proceeds and reduced resistance in the completed electrical circuit (proportional to conductor length) is continually monitored, using measured end-to-end voltage change or current in the circuit. Thermocouple and/or piezoelectric measurements provide consistency checks on local temperatures. |
| FILED | Friday, January 02, 2009 |
| APPL NO | 12/319918 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/64 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE42974 | Fossum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Eric R. Fossum (Wolfeboro, New Hampshire); Robert Nixon (Tehachapi, California) |
| ABSTRACT | A single chip camera which includes an intergrated integrated image acquisition portion and control portion and which has double sampling/noise reduction capabilities thereon. Part of the intergrated integrated structure reduces the noise that is picked up during imaging. |
| FILED | Thursday, April 09, 2009 |
| APPL NO | 12/421477 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Television 348/308 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08066979 | Dickens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Joseph C. Dickens (Ellicott City, Maryland); Fernando Otalora-Luna (College Park, Maryland); Jennifer A. Hammock (Washington, District of Columbia); Stephen L. Lapointe (Ormand Beach, Florida); Rocco T. Alessandro (Fort Pierce, Florida) |
| ABSTRACT | A composition for attracting female tropical root weevils (and/or repelling male tropical root weevils), containing (±)-linalool, cis-3-hexen-1-ol, and carvacrol, and optionally a carrier or carrier material known in the art. A method for attracting female tropical root weevils to an object or area, involving treating the object or area with a composition containing a female tropical root weevil attracting effective amount of (±)-linalool, cis-3-hexen-1-ol, and carvacrol, and optionally a carrier or carrier material. A method for repelling male tropical root weevils from an object or area, involving treating the object or area with a composition containing a male tropical root weevil repelling effective amount of (±)-linalool, cis-3-hexen-1-ol, and carvacrol, and optionally a carrier or carrier material. |
| FILED | Wednesday, July 09, 2008 |
| APPL NO | 12/217831 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/84 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08066988 | Teal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia); University of Florida Research Foundation Inc. (Gainesville, Florida) |
| INVENTOR(S) | Peter E. A. Teal (Gainesville, Florida); Baldwyn Torto (Gainesville, Florida); James H Tumlinson (State College, Pennsylvania); Drion G Boucias (Gainesville, Florida) |
| ABSTRACT | A Small Hive Beetle trap, which replaces the bottom board of beehives, includes a frame having three walls and a top surface, a trap plate, an entry means, and a trapping means. The trapping means provides a dark environment attractive to small hive beetles and contains a small hive beetle attractant made from pollen dough and inoculated with yeast that produces small hive beetle attracting volatiles. The yeast is a biologically pure strain of yeast producing hive beetle attracting volatiles designated yeast spp. NRRL Y-30722. |
| FILED | Tuesday, September 18, 2007 |
| APPL NO | 11/857106 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.510 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067171 | Khatibm |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hasan Khatibm (Madison, Wisconsin) |
| ABSTRACT | Single nucleotide polymorphic site at position 11646 of the bovine FGF2 gene is associated with improved fertilization rate and/or improved embryo survival rate, as well as improved milk production. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods. |
| FILED | Thursday, April 16, 2009 |
| APPL NO | 12/424796 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08068850 | Kleinfelder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Walter J Kleinfelder (Annapolis, Maryland); James E Meister (North Potomac, Maryland) |
| ABSTRACT | A method of locating a transmitter is disclosed. A communications link is established between multiple receiving stations and a control station, and used with a calibration signal to calibrate out the time delay of the communications link. A radiated signal from an unknown transmitter is received at a receiving station and sent to the control station over the communications link. The time of arrival is recorded. Upon receiving a user input, the communication link switches from transmitting the received radiated signal to transmitting the calibration signal. The start of calibration signal is timed to begin at the same time across all of the receiving stations. The communication link time delay for each link is calculated by subtracting the start time from the received time, and the communication link time delay is subtracted from the received time recorded for the radiated signal. TDOA calculations are made to locate the transmitter. |
| FILED | Tuesday, March 04, 2008 |
| APPL NO | 12/074512 |
| ART UNIT | 2617 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Telecommunications 455/456.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08069349 | Israel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Israel (Columbia, Maryland); Colin Richmond (Westminster, Maryland); Darrel Sharpe (Millersville, Maryland); Wohlgemuth Erik (Westminster, Maryland) |
| ABSTRACT | A method of securely transferring files from an un-trusted to a trusted network is disclosed. A file that is an archive file of many component files is separated into constituent files. Each file is stored on a server connected to an un-trusted network, and a series of initial checks, such as virus, file size, and file extension are performed. If the files pass, additional, file format specific security rules are applied. An open format transform is performed on proprietary format type files, and embedded file components are separated out. A user-definable security rule set is performed on each open format transform component. If all security tests pass, the file is reassembled and saved as a trusted file in the same format as the original file. |
| FILED | Wednesday, November 02, 2005 |
| APPL NO | 11/268411 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/165 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08069483 | Matlock |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States States of America as represented by the Director of the National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Kristen L. Matlock (Washington, District of Columbia) |
| ABSTRACT | A device for and method of detecting intrusion into a wireless network that includes a configuration file, a rules files, a main processor, a set packet processor, an initialize preprocessor, a parse rules file, an interface thread unit, a process packet unit, a decoder, a preprocess unit connected to the process packet unit; at least one preprocessor consisting of a rogue access point and transmit channel preprocessor, a NETSTUMBLER preprocessor, a MAC spoofing preprocessor, a DEAUTH flood preprocessor, an AUTH flood preprocessor, a rogue client preprocessor, a bridged network preprocessor, a rogue client valid access point preprocessor, valid client rogue access point preprocessor, an ad-hoc network preprocessor, a wrong channel preprocessor, a cloaking policy violation preprocessor, an encryption policy violation preprocessor, and a null SSID association policy violation preprocessor; and a detector. |
| FILED | Thursday, October 19, 2006 |
| APPL NO | 11/602430 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Information security 726/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08067264 | Ong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
| INVENTOR(S) | Beng S. Ong (Mississauga, Canada); Ping Liu (Mississauga, Canada); Lu Jiang (Oakville, Canada); Yu Qi (Mississauga, Canada); Yiliang Wu (Mississauga, Canada) |
| ABSTRACT | An electronic device containing a polythiophene wherein R represents a side chain, m represents the number of R substituents; A is a divalent linkage; x, y and z represent, respectively, the number of Rm substituted thienylenes, unsubstituted thienylenes, and divalent linkages A, respectively, in the monomer segment subject to z being 0 or 1, and n represents the number of repeating monomer segments in the polymer or the degree of polymerization. |
| FILED | Wednesday, July 25, 2007 |
| APPL NO | 11/782812 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067551 | Gerngross et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Glycofi, Inc. (Lebanon, New Hampshire) |
| INVENTOR(S) | Tillman U. Gerngross (Hanover, New Hampshire); Stefan Wildt (Lebanon, New Hampshire); Byung-Kwon Choi (Norwich, Vermont); Juergen Hermann Nett (Enfield, New Hampshire); Piotr Bobrowicz (Enfield, New Hampshire); Stephen R Hamilton (Enfield, New Hampshire); Robert C. Davidson (Enfield, New Hampshire) |
| ABSTRACT | The present invention relates to eukaryotic host cells having modified oligosaccharides which may be modified further by heterologous expression of a set of glycosyltransferases, sugar transporters and mannosidases to become host-strains for the production of mammalian, e.g., human therapeutic glycoproteins. The invention provides nucleic acid molecules and combinatorial libraries which can be used to successfully target and express mammalian enzymatic activities such as those involved in glycosylation to intracellular compartments in a eukaryotic host cell. The process provides an engineered host cell which can be used to express and target any desirable gene(s) involved in glycosylation. Host cells with modified oligosaccharides are created or selected. N-glycans made in the engineered host cells have a Man5GlcNAc2 core structure which may then be modified further by heterologous expression of one or more enzymes, e.g., glycosyltransferases, sugar transporters and mannosidases, to yield human-like glycoproteins. For the production of therapeutic proteins, this method may be adapted to engineer cell lines in which any desired glycosylation structure may be obtained. |
| FILED | Friday, November 07, 2008 |
| APPL NO | 12/291373 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/395 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 08067184 | Schwoebel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric D. Schwoebel (Woburn, Massachusetts); James D. Harper (Boston, Massachusetts); Martha S. Petrovick (Barre, Massachusetts); Frances E. Nargi (Littleton, Massachusetts); Todd H. Rider (Littleton, Massachusetts); Kristine E. Hogan (Danvers, Massachusetts); Richard H. Mathews (Chelmsford, Massachusetts); Joseph Lacirignola (Beverly, Massachusetts); Mark Hennessy (Cambridge, Massachusetts); Trina R. Vian (Groton, Massachusetts); Rose M. Joseph (Westford, Massachusetts); Raymond S. Uttaro (Lexington, Massachusetts); Shaun Berry (Chelmsford, Massachusetts); Bernadette Johnson (Hollis, New Hampshire); Mark A. Hollis (Concord, Massachusetts) |
| ABSTRACT | The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples. |
| FILED | Thursday, July 03, 2008 |
| APPL NO | 12/217471 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08068062 | Webb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | GBS Positioner, LLC. (Nashua, New Hampshire); AntennaSys, Inc. (Pelham, New Hampshire) |
| INVENTOR(S) | Spencer Webb (Pelham, New Hampshire); David Martin (Nashua, New Hampshire) |
| ABSTRACT | A low power, lightweight, collapsible and rugged antenna positioner for use in communicating with geostationary, geosynchronous and low earth orbit satellite. By collapsing, invention may be easily carried or shipped in a compact container. May be used in remote locations with simple or automated setup and orientation. Azimuth is adjusted by rotating an antenna in relation to a positioner base and elevation is adjusted by rotating an elevation motor coupled with the antenna. Manual orientation of antenna for linear polarized satellites yields lower weight and power usage. Updates ephemeris or TLE data via satellite. Algorithms used for search including Clarke Belt fallback, transponder/beacon searching switch, azimuth priority searching and tracking including uneven re-peak scheduling yield lower power usage. Orientation aid via user interface allows for smaller azimuth motor, simplifies wiring and lowers weight. Tilt compensation, bump detection and failure contingency provide robustness. |
| FILED | Friday, January 07, 2011 |
| APPL NO | 12/986891 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Communications: Radio wave antennas 343/766 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 08068214 | Bhargava et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Anuradha Bhargava (Reading, Massachusetts); Harold T. Wright (Pelham, New Hampshire); Kazimierz T. Grzeslak (Bedford, New Hampshire); Arnold Kravitz (Moorestown, New Jersey) |
| ABSTRACT | A centroiding method is provided for an optical tracking system including a laser used for countermeasuring purposes in which a pencil thin laser beam is accurately positioned onto a target through the use of centroiding techniques for ascertaining the position not only of the target but also the laser beam, with the centroiding techniques resulting in a sub-pixel level resolution. The sub-pixel resolution permits utilization of smaller cost-effective focal plane arrays by giving the small focal plane array a resolution associated with much larger focal plane arrays. |
| FILED | Monday, August 11, 2008 |
| APPL NO | 12/228511 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Optics: Measuring and testing 356/4.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08067365 | Westenfelder |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Christof Westenfelder (Salt Lake City, Utah) |
| ABSTRACT | The compositions and methods disclosed herein are for prevention or treatment of multi-organ failure with erythropoietin. The usefulness of the present invention is that erythropoietin may act to prevent the onset of MOF in a patient at risk of developing it. The present invention may further lessen the effect in one or more affected organs in a patient at risk of developing MOF or in one already diagnosed with it. |
| FILED | Tuesday, November 22, 2005 |
| APPL NO | 11/791287 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/7.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08065990 | Brusstar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Matthew J. Brusstar (South Lyon, Michigan); Charles L. Gray, Jr. (Pinckney, Michigan); Fakhri J. Hamady (Ann Arbor, Michigan) |
| ABSTRACT | A compression ignition internal combustion engine system combusts DME as fuel using high fuel injection pressures (e.g., above 800 bar) and low oxygen concentrations (e.g., below 17%, through high levels of EGR), thereby resulting in simultaneously very low NOx and PM engine-out emissions. |
| FILED | Friday, June 27, 2008 |
| APPL NO | 12/215452 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/568.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 08068426 | Sundararajan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jay Kumar Sundararajan (Cambridge, Massachusetts); Devavrat Shah (Newton, Massachusetts); Muriel Medard (Belmont, Massachusetts); Parastoo Sadeghi (Gungahlin, Australia) |
| ABSTRACT | A method, apparatus and computer program product for feedback-based online network coding is presented. In one embodiment, a transmitting node determines a linear combination of packets to transmit from a transmit queue. The transmitting node transmits the linear combination of packets. The transmitting node determines whether a packet can be removed from the transmit queue, wherein when a determination is made that a packet can be removed from the transmit queue then removing the packet from the transmit queue, and when a determination is made that a packet cannot be removed from the transmit queue then refraining from removing the packet from the transmit queue. |
| FILED | Friday, May 29, 2009 |
| APPL NO | 12/474738 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/235 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 08067160 | Brennan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Mark David Brennan (Jeffersonville, Indiana); D. Kay Phillips (Louisville, Kentucky) |
| ABSTRACT | The invention includes method of determining if a subject has a genetic predisposition to clinically diagnosed schizophrenia (SZ), schizotypal personality disorder (SPD), and/or schizoaffective disorder (SD). |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/859168 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08067742 | Winso et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Space Micro Inc. (San Diego, California) |
| INVENTOR(S) | James H Winso (Escondido, California); Michael D Fennell (San Diego, California) |
| ABSTRACT | An apparatus for detecting and determining a source azimuth for gamma radiation includes at least two scintillation crystals at angular offsets and directed toward a common plane of detection, photodetectors adjacent to each of the scintillation crystals for converting the light response of the scintillation crystals into distinct electrical signals, and a digital processing system configured to analyze spectral data from each electrical signal produced for each crystal. The digital processing system monitors a finite number of spectral windows corresponding to a selected set of radioisotopes, and uses one or more of the electrical signals to determine a signal intensity and a likely source azimuth for a detected radioisotope in the plane of detection. Another scintillation crystal directed outside of the common plane of detection may be used for three-dimensional detection. Related methods for detection and location of gamma ray sources are discussed. |
| FILED | Tuesday, June 12, 2007 |
| APPL NO | 11/808648 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 08069118 | McGrath |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Michael McGrath (Greensboro, North Carolina) |
| ABSTRACT | A method for processing a value-added electronic transmission, which includes obtaining user identification information (110), conveying software (120) to the user, where the software enables the user to selectively send electronic transmissions to intended recipients via a mediation site, and associating with the mediation site at least one value-added processing service, including carrier indication, sender indication, transmission identification, guaranteed delivery, address verification, address correction, archiving, and transmission security. The method further includes billing the user (140) for service rendered through the mediation site. |
| FILED | Friday, September 07, 2001 |
| APPL NO | 10/362874 |
| ART UNIT | 3718 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/59 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08066252 | Murata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Roy P. Murata (Cerritos, California); Raymond D. Fierro (Garden Grove, California); John J. Brown (Costa Mesa, California) |
| ABSTRACT | In one embodiment, a system for lifting and supporting a vehicle is described. The system includes at least one vehicle hoist fitting configured to distribute the weight of the vehicle along a skin of the vehicle, at least one removable bearing cup assembly configured to attach to said vehicle hoist fitting, and at least one trunnion assembly configured for attachment to a support structure and further configured to engage said removable bearing cup assembly. |
| FILED | Friday, January 12, 2007 |
| APPL NO | 11/622678 |
| ART UNIT | 3632 — Static Structures, Supports and Furniture |
| CURRENT CPC | Supports 248/671 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08067829 | Hughes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | John A. Hughes (Falls Church, Virginia); Thomas E. Love (Gainesville, Virginia); Eugene Lemoine (Manassas, Virginia); David H. Lee (Arlington, Virginia); Christopher Ebel (Manassas, Virginia) |
| ABSTRACT | A system and method are provided in which a first chip in a stacked multi-chip module configuration is affixed via one or more adhesion layers to a first portion of a partitioned interposer unit. Planar partitions of the interposer are physically bonded via multiple solder “bumps,” which possess high tensile strength but low resistance to horizontal shear force or torque. A second chip is affixed via one or more adhesion layers to the second portion of the partitioned interposer. The chips may thus be separated by horizontally and oppositely shearing or twisting the first and second portions of the partitioned interposer away from one another. |
| FILED | Wednesday, April 29, 2009 |
| APPL NO | 12/432672 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/686 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 29, 2011.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2011/fedinvent-patents-20111129.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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