FedInvent™ Patents
Patent Details for Tuesday, December 13, 2011
This page was updated on Monday, March 27, 2023 at 02:06 AM GMT
Department of Health and Human Services (HHS)
US 08074545 | Tabb et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | SAIC-Frederick, Inc. (Frederick, Maryland) |
INVENTOR(S) | Brian Carroll Tabb (Cumberland, Maryland); Keith Rogers (Singapore, Singapore) |
ABSTRACT | Systems and methods described herein for aligning a block in a microtome attempt to save time, money, and the sample by aligning a block in any rotary or cryostat microtome. One such device for aligning a block in a microtome has a knife holder component removably attached to a knife holder of the microtome and a pin alignment component extending vertically from the knife holder component in a direction substantially parallel to the block. The pin alignment component has a plurality of front pins extending from a front surface of the pin alignment component configured to slide in response to an angle of the block and a plurality of rear pins extending from a rear surface of the pin alignment component and coupled to the front pins. The rear pins are configured to indicate the extension of the front pins from the pin alignment component. |
FILED | Monday, August 01, 2011 |
APPL NO | 13/195569 |
ART UNIT | 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Cutting 083/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075181 | Stauffer et al. |
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ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Paul Rath Stauffer (Durham, North Carolina); Celestino John Gaeta (Carlsbad, California); Richard Alan Forber (Carlsbad, California); Doug Peder Bonnell (Castle Rock, Colorado) |
ABSTRACT | A thermal monitoring sheet measures surface temperature distributions of large areas, even over large, contoured surfaces. The sheet incorporates conduits that terminate or intersect at temperature measurement locations with a fixed relative arrangement to form a two-dimensional grid for sensing temperature distributions. |
FILED | Friday, May 29, 2009 |
APPL NO | 12/475151 |
ART UNIT | 2841 — Fluid Handling and Dispensing |
CURRENT CPC | Thermal measuring and testing 374/137 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075502 | Parks |
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ASSIGNEE(S) | Pressure Profile Systems, Inc. (Los Angles, California) |
INVENTOR(S) | Thomas R. Parks (Hermosa Beach, California) |
ABSTRACT | A system for visually indicating, in real time or post hoc, values of a physical property detected over a period of time along a dimension of an organism to a user on a temporal plot and a profile plot, either individually or concurrently. The detected values may be visually indicated on the temporal plot using any of a variety of techniques, including, but not limited to, a contour technique, a line trace technique or a mesh plot technique. Further, the detected values may be visually indicated on the profile plot using any of a variety of techniques, including, but not limited to a contour technique, a line trace technique or a histogram technique. To provide a finer spatial resolution, values may be interpolated for locations between the locations at which values were detected, and these values may be displayed on the temporal plot and the profile plot. |
FILED | Monday, January 12, 2009 |
APPL NO | 12/352064 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/593 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075562 | Murphy et al. |
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ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | William L. Murphy (Madison, Wisconsin); Jae-Sam Lee (Houston, Texas); Mark D. Markel (Middleton, Wisconsin); Ben K. Graf (Madison, Wisconsin) |
ABSTRACT | Controlled release of biopharmaceutical growth factors from a hydroxyapatite coating on a bioresorbable interference screw used in cruciate ligament reconstruction surgery on a human. Biologically active scaffolds, such as interference bone screws used for ligament fixation, made by growing calcium phosphate-based hydroxyapatite coatings on bioresorbable poly(α-hydroxy ester) scaffolds that provide controlled mineral dissolution and controlled release of bone morphogenetic protein-2. The biologically active scaffold provides improved bioavailability of BMP-2 growth factor that in turn provides enhanced graft-bone healing in the tibial bone tunnel. The coating method uses surface hydrolysis and modified simulated body fluid incubation which does not require solvent or heat and is conducted at room temperature. |
FILED | Wednesday, June 25, 2008 |
APPL NO | 12/145672 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Surgery 66/77 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075879 | Rajashekara et al. |
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ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Gireesh Rajashekara (Madison, Wisconsin); Gary Splitter (Brooklyn, Wisconsin) |
ABSTRACT | Certain attenuated mutants of Brucella, especially B. melitensis, B. abortus, B. suis and B. ovis, when administered to a human or animal trigger a protective immune response such that subsequent challenge with virulent Brucella of the same species does not result in disease or results in much less severe symptoms. Functional inactivation of galE, a virB gene or the operon (ORFs 1087-1090) comprising the gene encoding β-hexosaminidase (BMEI1087) and a lytic murein transglycosylase gene (BMEI1088). A specific example of the attenuated galE mutant which produces a protective immune response is B. melitensis GR024. The specific example of an inactivated ORF1087-1090 operon is B. melitensis GR026; it has an insertion mutation in the promoter region upstream of ORF 1090. Vaccination with live cells of either or both of these mutants results in a T cell response which protects the human or animal against challenge with virulent B. melitensis. Similar strategies for protective immunity using live attenuated mutants are useful for B. abortus, B. suis and B. ovis as well. |
FILED | Thursday, October 15, 2009 |
APPL NO | 12/580213 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075900 | Figdor et al. |
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ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Carl Gustav Figdor (Hertogenbosch, Netherlands); Gosse Jan Adema (Groesbeek, Netherlands) |
ABSTRACT | The present invention is concerned with cancer treatment and diagnosis, especially with melanoma associated peptide analogues with improved immunogenicity, epitopes thereof; vaccines against melanoma, tumor infiltrating T lymphocytes recognizing the antigen and diagnostics for the detection of melanoma and for the monitoring of vaccination. The peptides according to the invention can be exploited to elicit native epitope-reactive Cm. Usage of the peptides with improved immunogenicity may contribute to the development of CTL-epitope based vaccines in viral disease and cancer. |
FILED | Monday, December 06, 2010 |
APPL NO | 12/961217 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075903 | Whitehead et al. |
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ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Stephen S. Whitehead (Montgomery Village, Maryland); Brian R. Murphy (Bethesda, Maryland); Lewis Markoff (Bethesda, Maryland); Barry Falgout (Rockville, Maryland); Joseph Blaney (Frederick, Maryland); Kathryn Hanley (Las Cruces, New Mexico) |
ABSTRACT | The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (Δ30) in the 3′-untranslated region of the genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengue viruses of serotypes 1, 2, 3, and 4. |
FILED | Wednesday, March 04, 2009 |
APPL NO | 12/398043 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/202.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075922 | Stamler et al. |
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ASSIGNEE(S) | Montana State University-Bozeman (Bozeman, Montana); Duke University (Durham, North Carolina) |
INVENTOR(S) | Jonathan S. Stamler (Chapel Hill, North Carolina); David J. Singel (Bozeman, Montana) |
ABSTRACT | Contrary to current opinion that nitrite in general oxidizes hemoglobin with elimination of active nitric oxide, deoxygenated hemoglobin reacts with low concentration inorganic nitrite to produce very stable iron nitrosyl hemoglobin which on delivery into the body is converted to a hemoglobin capable of nitric oxide delivery and provides vasodilator and antiplatelet activity. This provides basis for ameliorated risk blood product transfusions. |
FILED | Wednesday, December 10, 2003 |
APPL NO | 10/538404 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/718 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075956 | Geddes et al. |
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ASSIGNEE(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
INVENTOR(S) | Chris D. Geddes (Bel Air, Maryland); Kadir Aslan (Baltimore, Maryland) |
ABSTRACT | The present invention relates to methods for functionally modifying a polymeric surface for subsequent deposition of metallic particles and/or films, wherein the polymeric surface is modified by increasing hydroxyl and/or amine functional groups thereby providing an activated polymeric surface for deposition of metallic particles to form a fluorescence sensing device. The device can be used for metal-enhanced fluorescence of fluorophores positioned above the metallic particles that can be readily applied to diagnostic or sensing applications of metal-enhanced fluorescence. |
FILED | Friday, October 28, 2005 |
APPL NO | 11/718560 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Coating processes 427/402 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076059 | Pizzo et al. |
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ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Salvatore V. Pizzo (Bahama, North Carolina); Justin P. Hart (Durham, North Carolina); James B. McLachlan (Raleigh, North Carolina); Herman F. Staats (Hillsborough, North Carolina); Soman N. Abraham (Chapel Hill, North Carolina) |
ABSTRACT | A composition for eliciting an immune response to an immunogen comprises an immunogen in combination with a mast cell membrane activator such as compound 48/80. Any suitable immunogen may be employed, such as an antibody-inducing determinant, a lipid, a peptide (e.g., an antibody-inducing peptide), a carbohydrate, an immunogen derived from a virus or cancer cell, etc. Methods of use are also described. |
FILED | Friday, April 02, 2004 |
APPL NO | 10/817023 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076063 | Fan |
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ASSIGNEE(S) | Illumina, Inc. (San Diego, California) |
INVENTOR(S) | Jian-Bing Fan (San Diego, California) |
ABSTRACT | The present invention is directed to sensitive and accurate multiplexed assays for target analyte detection and detection of methylation in nucleic acid samples. |
FILED | Wednesday, December 03, 2003 |
APPL NO | 10/537204 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076070 | Chen et al. |
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ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Lin Chen (Los Angeles, California); Reza Kalhor (Los Angeles, California) |
ABSTRACT | The invention relates to the use of GCC (Genome Conformation Capture) technology in determining the three dimensional arrangement of an entire genome. |
FILED | Thursday, August 06, 2009 |
APPL NO | 12/537138 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076071 | Rossi et al. |
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ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | John J. Rossi (Alta Loma, California); Nan-Sook Lee (Pasadena, California) |
ABSTRACT | Methods for producing interfering RNA molecules in mammalian cells are provided. Therapeutic uses for the expressed molecules, including inhibiting expression of HIV, are also provided. |
FILED | Tuesday, September 14, 2010 |
APPL NO | 12/881509 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076075 | Clelland et al. |
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ASSIGNEE(S) | The Research Foundation for Mental Hygiene, Inc. (Menands, New York) |
INVENTOR(S) | James D. Clelland (New York, New York); Catherine L. Clelland (New York, New York) |
ABSTRACT | An assay for a GCH1 allele and associated genotype for the screening, prediction, diagnosis, prognosis, treatment and treatment response of psychiatric, neuropsychiatric, and neurological disorders, such as schizophrenia, schizoaffective disorder and bipolar disorder, and for defining treatments of such disorders. The presence of a variant in the GCH1 gene, alone or in conjunction with a measurement of low or altered biopterin, or altered BH4 system measures, is used to screen for or diagnose subjects at high risk for developing a psychiatric, neuropsychiatric, or neurological disorders. The assay of the GCH1 genotype, with or without biopterin or a BH4 or BH4 system assay, may also be used to determine antipsychotic or mood stabilizer medication, as well as other treatments. For subjects with an impaired BH4 system, treatments to increase or normalize biopterin, BH4, or the BH4 system can also be used, such as BH4 supplementation, lithium treatment, phenylalanine treatment, or other treatments and therapies. |
FILED | Wednesday, October 17, 2007 |
APPL NO | 11/873971 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076081 | Kurnit et al. |
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ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | David M. Kurnit (Ann Arbor, Michigan); Michael D. Kane (West Lafayette, Indiana) |
ABSTRACT | The present invention comprises, without limitation, systems, methods, and compositions for the detection, identification, and quantification, down to the single copy level, of human papillomavirus (HPV) in biological samples, including but not limited to, mammalian body fluids and cervix scrapings, for purposes of detection, treatment and/or management of cancer and dysplasia. |
FILED | Tuesday, January 17, 2006 |
APPL NO | 11/333738 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076088 | Weinberg et al. |
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ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Aaron Weinberg (Shaker Heights, Ohio); Santosh K. Ghosh (Mayfield Heights, Ohio) |
ABSTRACT | A method of detecting β-defensin in a bodily sample from a subject includes reducing the electrostatic interaction between β-defensin and negatively charged moieties in the bodily sample prior to detecting the β-defensin with an antibody or epitope binding fragment thereof. |
FILED | Monday, February 23, 2009 |
APPL NO | 12/390890 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076095 | Dertinger |
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ASSIGNEE(S) | Litron Laboratories, Ltd. (Rochester, New York) |
INVENTOR(S) | Stephen D. Dertinger (Webster, New York) |
ABSTRACT | A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody having binding specificity for a surface marker for reticulocytes, a second fluorescent labeled antibody having binding specificity for a surface marker for platelets, and a nucleic acid staining dye that stains DNA (micronuclei) in erythrocyte populations. Because the fluorescent emission spectra of the first and second fluorescent labeled antibodies do not substantially overlap with one another or with the emission spectra of the nucleic acid staining dye, upon excitation of the labels and dye it is possible to detect the fluorescent emission and light scatter produced by the erythrocyte populations and platelets, and count the number of cells from one or more erythrocyte populations in said sample. In particular, the use of the second antibody prevents interference by platelet-associated aggregates in the scoring procedures. |
FILED | Wednesday, December 08, 2010 |
APPL NO | 12/962788 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.250 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076099 | Chambers et al. |
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ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | James Chambers (San Antonio, Texas); Jieh-Juen Yu (San Antonio, Texas); Karl E. Klose (San Antonio, Texas); M. Neal Guentzel (San Antonio, Texas); Bernard P. Arulanandam (San Antonio, Texas) |
ABSTRACT | The instant invention concerns Francisella bacteria mediated degradation of alkaline phosphatase (AP). Detection of AP degradation may be used to determine the presence of Francisella bacteria in a sample. Furthermore, methods for identifying and treating Francisella infections by detecting AP degradation are described. Methods of the invention also concerns methods for treating Francisella infection by inhibiting AP degradation. |
FILED | Thursday, June 05, 2008 |
APPL NO | 12/133963 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/34 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076100 | Pavlakis |
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ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | George N. Pavlakis (Rockville, Maryland) |
ABSTRACT | Nucleic acid constructs containing HIV-1 gag/pol and SIV gag or SIV env genes which have been mutated to remove or reduce inhibitory/instability sequences are disclosed. Viral particles and host cells containing these constructs and/or viral particles are also disclosed. The exemplified constructs and viral particles of the invention may be useful in gene therapy for numerous disorders, including HIV infection, or as a vaccine for HIV-1 immunotherapy and immunoprophylaxis. |
FILED | Wednesday, October 02, 2002 |
APPL NO | 10/263020 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076103 | Kobilka et al. |
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ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Brian Kobilka (Palo Alto, California); Michael Bokoch (Menlo Park, California) |
ABSTRACT | Methods for producing stable isotope-labeled recombinant protein are provided. The methods include isolating a stable isotope-labeled recombinant protein from a Trichoplusia ni larva expressing a recombinant protein, which Trichoplusia ni larva has ingested a food source comprising stable isotope-labeled algae, thereby resulting in incorporation of a stable isotope into the recombinant protein to produce the stable isotope-labeled recombinant protein. |
FILED | Thursday, December 18, 2008 |
APPL NO | 12/338816 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076116 | Grozinger et al. |
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ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Christina M. Grozinger (Cambridge, Massachusetts); Christian A. Hassig (Berkeley, California); Stuart L. Schreiber (Boston, Massachusetts) |
ABSTRACT | The invention provides histone deacetylase class II nucleic acids and polypeptides, methods and reagents for their use, and related compounds including small molecule libraries containing class II histone deacetylase inhibitors. |
FILED | Thursday, February 12, 2009 |
APPL NO | 12/370390 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/227 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076130 | Galen et al. |
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ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | James E. Galen (Sykesville, Maryland); Christofer Vindurampulle (Thornbury, Australia) |
ABSTRACT | The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid Maintenance System. The invention optimizes the maintenance of expression plasmids at two independent levels by: (1) removing sole dependence on balanced lethal maintenance functions; and (2) incorporating at least one plasmid partition function to prevent random segregation of expression plasmids, thereby enhancing their inheritance and stability. The Plasmid Maintenance System may be employed within a plasmid which has been recombinantly engineered to express a variety of expression products. |
FILED | Wednesday, October 04, 2006 |
APPL NO | 11/542264 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076159 | Gambhir et al. |
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ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Sanjiv S. Gambhir (Portola Valley, California); Ramasamy Paulmurugan (Mountain View, California) |
ABSTRACT | Briefly described, embodiments of this disclosure include ligand-regulable transactivation systems, methods of producing ligand-regulable transactivation systems, methods of using ligand-regulable transactivation systems, reporter polynucleotides, method of producing reporter polynucleotides, activator fusion proteins, methods of producing activator fusion proteins, methods of regulating gene expression in vitro and in vivo for gene therapy, methods of screening estrogen receptor modulators with therapeutic treatments (e.g., anticancer, antiosteoporosis, and hormone replacement treatments), method of screening compounds (e.g., drugs and environmental pollutants) for the estrogenic effect, methods of evaluating the estrogen receptor pathway under different pathological conditions are provided, and the like. |
FILED | Wednesday, February 10, 2010 |
APPL NO | 12/658528 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/501 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076283 | Marchionni et al. |
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ASSIGNEE(S) | Acorda Therapeutics, Inc. (Hawthorne, New York); Beth Israel Deaconesss Medical Center (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Mark Marchionni (Arlington, Massachusetts); Ralph Kelly (Chestnut Hill, Massachusetts); Beverly Lorell (Needham, Massachusetts); Douglas B. Sawyer (Brookline, Massachusetts) |
ABSTRACT | The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene. |
FILED | Tuesday, December 29, 2009 |
APPL NO | 12/655361 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076303 | Iyer et al. |
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ASSIGNEE(S) | Spring Bank Pharmaceuticals, Inc. (Milford, Massachusetts) |
INVENTOR(S) | Radhakrishnan P. Iyer (Shrewsbury, Massachusetts); Seetharamaiyer Padmanabhan (Lexington, Massachusetts) |
ABSTRACT | The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. |
FILED | Tuesday, December 12, 2006 |
APPL NO | 11/637520 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/43 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076304 | Ford et al. |
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ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
INVENTOR(S) | Heide L. Ford (Denver, Colorado); Ricardo D. Coletta (Sao Paulo, Brazil); Arthur R. Pardee (Cambridge, Massachusetts); Justin Lamb (Cambridge, Massachusetts) |
ABSTRACT | The present invention relates to compositions and methods for cancer therapeutics. In particular, the present invention provides compositions and methods for inhibiting cancer metastasis by inhibiting cyclin A1. |
FILED | Monday, April 25, 2005 |
APPL NO | 11/113644 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076309 | Pagano et al. |
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ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Michele Pagano (New York, New York); Jeffrey R. Skaar (New York, New York); Angelo Peschiaroli (Rome, Italy); N. Valerio Dorrello (Caivano, Italy) |
ABSTRACT | The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates to methods and kits to screen for related agents that induce apoptosis. Additionally, the invention relates to assays for screening compounds capable of acting as USP47 inhibitors. |
FILED | Tuesday, April 28, 2009 |
APPL NO | 12/431336 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076318 | Lawrence et al. |
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ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
INVENTOR(S) | David S. Lawrence (Hartsdale, New York); Richard G. Pestell (Great Falls, Virginia); Christopher Albanese (Pelham Manor, New York) |
ABSTRACT | Provided are caged compounds comprising a ligand that specifically reacts with a receptor not naturally present in mammals. The cage is released from the ligand upon illumination of the compound with light. Also provided are cells transfected with a gene of interest and a gene encoding a receptor, the gene of interest operably linked to a genetic element capable of being induced by the receptor when bound to a ligand, and the receptor not naturally present in the species of the cell. The cells also comprise a caged ligand of the receptor. Additionally provided are methods of inducing a gene of interest in the above cells. Also provided are methods of repressing a gene of interest in a cell using caged ligands of receptors. Methods are additionally provided for inducing elimination of a target sequence in a cell of a species, using a caged ligand and a recombinase. |
FILED | Wednesday, October 22, 2003 |
APPL NO | 10/532009 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/171 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076347 | Chu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Chung K. Chu (Athens, Georgia); Yung-chi Cheng (Woodbridge, Connecticut) |
ABSTRACT | (−)-(2S,4S)-1-(2-Hydroxymethyl-1,3-dioxolan-4-yl)cytosine (also referred to as (−)-OddC) or its derivative and its use to treat cancer in animals, including humans. |
FILED | Monday, March 05, 2007 |
APPL NO | 11/713975 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/274 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076375 | Sefton et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
INVENTOR(S) | Bartholomew M. Sefton (La Jolla, California); Roberta J. Schulte (San Diego, California) |
ABSTRACT | This disclosure ascribes new functions to derivatives of tetralin, anthraquinone, naphthylamine, tri-amino-pyrimidine, xanthen-3-one, and/or cinnamic acid (including, for example, NSC270718R, NSC117285R, NSC170008Y, NSC306711P, NSC119913X, NSC119915Z, NSC119911V, NSC119910U, NSC128437O, NSC125908P, NSC9600Q, or NSC13778J, each obtained from the Structure Diversity Set, National Institutes of Health, National Cancer Institute, Developmental Therapeutics Program). These compounds are shown to be effective inhibitors of viral essential protein kinases (such as poxvirus B1 and/or F10 protein kinases). Exemplary chemical structures for viral protein kinase (VPK) inhibitors are provided, as are methods of using such compounds, for instance, to inhibit VPK activity and/or poxvirus growth, and/or for the treatment of poxvirus infection. Also provided are pharmaceutical compositions including disclosed VPK inhibitors. |
FILED | Tuesday, October 10, 2006 |
APPL NO | 12/090081 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/569 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076450 | Simon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Morehouse School of Medicine (Atlanta, Georgia) |
INVENTOR(S) | Roger P. Simon (Portland, Oregon); Zhi-Gang Xiong (Beaverton, Oregon) |
ABSTRACT | A system, including methods and compositions, for treatment of ischemia. |
FILED | Friday, March 16, 2007 |
APPL NO | 11/724859 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076451 | Reshetnyak et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Governors for Higher Education, State of Rhode Island and Providence Plantations (Providence, Rhode Island); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Yana K. Reshetnyak (South Kingstown, Rhode Island); Oleg A. Andreev (South Kingstown, Rhode Island); Ursula Lehnert (Richmond, United Kingdom); Donald M. Engelman (New Haven, Connecticut) |
ABSTRACT | A polypeptide with a predominantly hydrophobic sequence long enough to span a membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more dissociable groups inserts across a membrane spontaneously in a pH-dependant fashion placing one terminus inside cell. The polypeptide conjugated with various functional moieties delivers and accumulates them at cell membrane with low extracellular pH. The functional moiety conjugated with polypeptide terminus placed inside cell are translocated through the cell membrane in cytosol. The peptide and its variants or non-peptide analogs can be used to deliver therapeutic, prophylactic, diagnostic, imaging, gene regulation, cell regulation, or immunologic agents to or inside of cells in vitro or in vivo in tissue at low extracellular pH. The claimed method provides a new approach for diagnostic and treatment diseases with naturally occurred (or artificially created) low pH extracellular environment such as tumors, infarction, stroke, atherosclerosis, inflammation, infection, or trauma. The method allows to translocate cell impermeable molecules (peptides, toxins, drugs, inhibitors, nucleic acids, peptide nucleic acids, imaging probes) into cells at low pH. The method allows to attach to the cell surface a variety of functional moieties and particles including peptides, polysaccharides, virus, antigens, liposomes and nanoparticles made of any materials. |
FILED | Monday, July 16, 2007 |
APPL NO | 11/778323 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076457 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Eric F. Johnson (Encinitas, California); Jason K. Yano (Vista, California) |
ABSTRACT | The teachings relates to the three-dimensional structure of a crystal of a cytochrome protein complexed with a ligand. The three-dimensional structure of four cytochrome P450 2A6-ligand complexes are disclosed. Cytochrome P450 2A6-ligand crystal structures, wherein the ligand is an inhibitor molecule, are useful for providing structural information that may be integrated into drug screening and drug design processes. Thus, the teachings also relate to methods for utilizing a crystal structure of a cytochrome P450 2A6-ligand complex for identifying, designing, selecting, or testing inhibitors of the cytochrome protein. Such inhibitors are useful as therapeutics for the treatment or modulation of i) diseases; ii) disease symptoms; or iii) the effect of other physiological events mediated by the cytochrome. |
FILED | Friday, May 27, 2011 |
APPL NO | 13/117470 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076467 | Niu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Research Foundation of State University of New York (Albany, New York); Cornell University (Ithaca, New York) |
INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Albany, New York); Hua Shi (Ithaca, New York); John T. Lis (Ithaca, New York) |
ABSTRACT | The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors. |
FILED | Tuesday, October 13, 2009 |
APPL NO | 12/578231 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076470 | Norris |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Steven J. Norris (Houston, Texas) |
ABSTRACT | The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies. |
FILED | Tuesday, December 07, 2010 |
APPL NO | 12/962154 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076496 | Saxon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Eliana Saxon (Albany, California); Carolyn Ruth Bertozzi (Berkeley, California) |
ABSTRACT | The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). |
FILED | Tuesday, March 08, 2011 |
APPL NO | 13/043274 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 552/10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076501 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Xiaolian Gao (Houston, Texas); Zhuo Xiaochruan (Houston, Texas); Wu Yao (Houston, Texas); Jean-Phillipe Pollols (College Station, Texas) |
ABSTRACT | This invention describes reagent precursors and methods for chemical and biochemical reactions. These reagent precursors that can be activated in solution upon irradiation to generate reagents required for the subsequent chemical reactions. Specifically, photogenerated reagents (PGR) are useful for controlling parallel combinatorial synthesis and various chemical and biochemical reactions. |
FILED | Monday, May 18, 2009 |
APPL NO | 12/454471 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Organic compounds 560/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076657 | Mackie et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Thomas R. Mackie (Verona, Wisconsin); David C. Westerly (Madison, Wisconsin) |
ABSTRACT | An improved beam forming system for ions used in radiation treatment employs a magnet system of successive quadrupole magnets to convert an ion pencil beam to a fan beam with reduced neutrons production compared with conventional beam spreading techniques using scattering foils. |
FILED | Wednesday, February 27, 2008 |
APPL NO | 12/439390 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/492.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076936 | Borthakur et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Ari Borthakur (Philadelphia, Pennsylvania); Ravinder Reddy (Gladwyne, Pennsylvania); Sridhar Charagundla (McLean, Virginia); Jyothsna Charagundla, legal representative (McLean, Virginia) |
ABSTRACT | Provided are methods and systems for rapid MRI imaging-scanning that provides 2D or 3D coverage, high precision, and high-temporal efficiency, without exceeding SAR limits. In one embodiment, a pulse sequence process is performed that includes a T1ρ preparation period, followed by a very rapid image acquisition process, which acquires multiple lines of k-space data. The combination of T1ρ preparation and acquisition of multiple lines of k-space, allows scan times to be shortened by as much as 3- or 4-fold or more, over conventional MRI scanning methods. |
FILED | Thursday, April 16, 2009 |
APPL NO | 12/425130 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/307 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076939 | Setsompop et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Kawin Setsompop (Cambridge, Massachusetts); Elfar Adalsteinsson (Belmont, Massachusetts); Vijayanand Alagappan (Aurora, Ohio); Lawrence Wald (Cambridge, Massachusetts) |
ABSTRACT | A system and method for producing an image indicative of characteristics of a radiofrequency (“RF”) coil with a magnetic resonance imaging (“MRI”) system is disclosed. The method includes acquiring MR signals while performing a pulse sequence with the MRI system and driving the RF coil at a selected transmission power. This process is repeated a plurality of times to drive the RF coil at a different transmission powers during each repetition. A plurality of images are reconstructed from the acquired MR signals and an image indicative of RF reception characteristics of the RF coil is produced from the reconstructed images. Subsequently, an image indicative of RF transmission characteristics of the RF coil is produced using the image indicative of the RF receiver response. More specifically, only one data acquisition is necessary for each RF coil element to produce the image indicative of the RF transmission characteristics for that coil element. |
FILED | Friday, April 10, 2009 |
APPL NO | 12/422017 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/309 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077312 | Benni et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | CAS Medical Systems, Inc. (Branford, Connecticut) |
INVENTOR(S) | Paul B. Benni (Guilford, Connecticut); Andrew Kersey (Wallingford, Connecticut); Krystian Gieryk (New Haven, Connecticut) |
ABSTRACT | A method and apparatus for calibrating an NIRS system which includes a sensor portion and for evaluating an NIRS system for proper functioning is provided that includes an enclosure with at least two windows disposed in a wall of the enclosure. The windows allow the light source and one or more detectors of an NIRS system sensor to interface with the enclosure. One window is dedicated to the light source while each light detector has a window dedicated thereto. Thus, the enclosure includes a number of windows equal to the number of light detectors in the NIRS system sensor plus one. The inner surface of the wall(s) of the enclosure is of a light-absorbing color; e.g., black. A diffuse reflectance member of a light-reflecting color, e.g., white, is disposed in the enclosure spaced apart from the surface with the windows disposed therein. |
FILED | Friday, November 03, 2006 |
APPL NO | 12/092778 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/320 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077325 | Choma et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Michael Choma (Durham, North Carolina); Joseph A. Izatt (Raleigh, North Carolina); Audrey Ellerbee (Durham, North Carolina); Marinko Sarunic (Durham, North Carolina) |
ABSTRACT | Structure profiles from optical interferometric data can be identified by obtaining a plurality of broadband interferometric optical profiles of a structure as a function of structure depth in an axial direction. Each of the plurality of interferometric optical profiles include a reference signal propagated through a reference path and a sample signal reflected from a sample reflector in the axial direction. An axial position corresponding to at least a portion of the structure is selected. Phase variations of the plurality of interferometric optical profiles are determined at the selected axial position. A physical displacement of the structure is identified based on the phase variations at the selected axial position. |
FILED | Wednesday, December 09, 2009 |
APPL NO | 12/634153 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/517 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077958 | Qian et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Wei Qian (Wesley Chapel, Florida); Dansheng Song (Tampa, Florida); Tatyana A. Zhukov (Lutz, Florida) |
ABSTRACT | The present invention is a computer-aided pathological diagnosis method for the classification of cancer cells in a tissue specimen based on a digital cellular image of the tissue specimen. The method of the present invention includes the steps of, extracting the histological characteristic features of the cellular image using preprocessing algorithms having adaptive strategies to enhance the cellular image, declustering the extracted histological characteristic features of the cellular image to isolate the individual cells and the nuclei inside the cells, segmenting the declustered cellular image, labeling the segmented cellular image and classifying the cells in the labeled cellular image as cancer cells or non-cancer cells. |
FILED | Monday, July 02, 2007 |
APPL NO | 11/772288 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/133 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078250 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | CAS Medical Systems, Inc. (Branford, Connecticut) |
INVENTOR(S) | Bo Chen (Derby, Connecticut); Paul B. Benni (Guilford, Connecticut) |
ABSTRACT | A method and apparatus for non-invasively determining the blood oxygenation within a subject's tissue is provided that utilizes a near infrared spectrophotometric (NIRS) sensor capable of transmitting a light signal into the tissue of a subject and sensing the light signal once it has passed through the tissue via transmittance or reflectance. |
FILED | Thursday, March 16, 2006 |
APPL NO | 11/376894 |
ART UNIT | 3777 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery 6/331 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078251 | Pologe et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Kestrel Labs, Inc. (Boulder, Colorado) |
INVENTOR(S) | Jonas Alexander Pologe (Boulder, Colorado); Theodore Philip Delianides (Boulder, Colorado) |
ABSTRACT | A photoplethysmographic sensor designed for use on the presenting portion of a fetus during labor and delivery. The sensor has a non-deployed state in which the sensor presents a smaller footprint, or cross sectional area, for transvaginal insertion. Once the sensor is applied to the fetal tissue it is moved into the deployed state, which has a larger footprint or cross sectional area, than the sensor does in the non-deployed state. The deployed state optimizes the physical distance between the light emitter and the photodetector to maximize the photoplethysmographic measurement accuracy from the fetal tissue. |
FILED | Thursday, June 22, 2006 |
APPL NO | 11/473092 |
ART UNIT | 3777 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery 6/338 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078259 | Prince |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Martin R. Prince (Ann Arbor, Michigan) |
ABSTRACT | Systems and methods for contrast-enhanced magnetic resonance angiography in which both arterial-phase image data and post-contrast image data is collected. |
FILED | Tuesday, March 30, 2010 |
APPL NO | 12/750027 |
ART UNIT | 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery 6/420 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078265 | Mahmood et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Umar Mahmood (Winchester, Massachusetts); Ralph Weissleder (Peabody, Massachusetts); Rahul A. Sheth (Houston, Texas); Rabi Upadhyay (Boston, Massachusetts) |
ABSTRACT | An imaging system divides image pixels intensities by exposure time to generate image data in units of intensity per time. The imaging system divides a fluorescent light image in intensity per time units by an excitation light image in intensity per time units to provide a quantitative corrected fluorescent light image that is generally invariant to position of an imaging instrument relative to a biological tissue being imaged. |
FILED | Tuesday, July 11, 2006 |
APPL NO | 11/456625 |
ART UNIT | 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery 6/476 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078284 | Greenberg et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
INVENTOR(S) | Robert J. Greenberg (Los Angeles, California); Matthew J. McMahon (Los Angeles, California); James Singleton Little (Saugus, California); Kelly H. McClure (Simi Valley, California); Brian V. Mech (Stevenson Ranch, California); Neil Hamilton Talbot (Montrose, California); Jordan M. Neysmith (Pasadena, California) |
ABSTRACT | Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, and cortical stimulation, and many related purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow. Common flexible circuit fabrication techniques generally require that a flexible circuit electrode array be made flat. Since neural tissue is almost never flat, a flat array will necessarily apply uneven pressure. Further, the edges of a flexible circuit polymer array may be sharp and cut the delicate neural tissue. By applying the right amount of heat to a completed array, a curve can be induced. With a thermoplastic polymer it may be further advantageous to repeatedly heat the flexible circuit in multiple molds, each with a decreasing radius. Further, it is advantageous to add material along the edges. It is further advantageous to provide a fold or twist in the flexible circuit array. Additional material may be added inside and outside the fold to promote a good seal with tissue. |
FILED | Tuesday, September 19, 2006 |
APPL NO | 11/523965 |
ART UNIT | 3766 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Surgery: Light, thermal, and electrical application 67/53 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 08074559 | Altobelli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
INVENTOR(S) | David E. Altobelli (Hollis, New Hampshire); N. Christopher Perry (Manchester, New Hampshire) |
ABSTRACT | A dynamic support apparatus having a frame, a dynamic interface, a temperature control mechanism, and a control system. The dynamic interface is capable of changing its geometry and is disposed on the top surface of the frame. The control system is operably connected to the dynamic interface and controls the changing geometry of the dynamic interface. There is also a temperature control mechanism disposed on the top surface of the frame for maintaining a comfortable temperature and moisture environment between the apparatus and the user's body. |
FILED | Tuesday, February 16, 2010 |
APPL NO | 12/706340 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Expansible chamber devices 092/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08074572 | Bland et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Geoffrey A. Bland (King George, Virginia); Larry Stephen Weedon, II (King George, Virginia) |
ABSTRACT | A cargo round (e.g., 155 mm high explosive projectile) is provided for dispensing submunitions. The round includes a nose tip, a casing attached thereto forming a chamber, a tail and a payload in the chamber between the tip and tail. The payload includes a plurality of axi-symmetric darts mounted on a plurality of front and rear tandem plates. Each dart has fore and aft ends along a polar axis. Each dart is shaped as a cone at its fore end and includes a cavity at its aft end. Each plate has a plurality of orifices arranged in a regular pattern. Each orifice receives a corresponding dart to protrude from both obverse and reverse sides of the plate. Each fore end of its dart in the rear plate inserts into the cavity of a counterpart dart in the front plate, and each plate shears apart on release of the payload to disperse the darts. The plates preferably have a plurality of notches arranged in rows on the reverse side, together with a lip at an outer rim and bounded recess region within the lip on the obverse side, with the orifices are disposed in the region. |
FILED | Monday, March 30, 2009 |
APPL NO | 12/386177 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition and explosives 12/489 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08074661 | Hutson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Michael Shane Hutson (Durham, North Carolina); Glenn S. Edwards (Chapel Hill, North Carolina) |
ABSTRACT | A method and apparatus for ablating material. The material is preferably a heterogenous or composite material, such as animal tissue. A table top laser system can be employed in the invention. Alternatively, a larger laser, such as a free electron laser can be employed. |
FILED | Tuesday, April 29, 2003 |
APPL NO | 10/516163 |
ART UNIT | 3769 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Surgery 128/898 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08074752 | Rudakevych |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | iRobot Corporation (Bedford, Massachusetts) |
INVENTOR(S) | Pavlo E. Rudakevych (Arroyo Grande, California) |
ABSTRACT | A mobile robot includes a robot chassis having a forward end, a rearward end and a center of gravity. The robot includes a driven support surface to propel the robot and first articulated arm rotatable about an axis located rearward of the center of gravity of the robot chassis. The arm is pivotable to trail the robot, rotate in a first direction to raise the rearward end of the robot chassis while the driven support surface propels the chassis forward in surmounting an obstacle, and to rotate in a second opposite direction to extend forward beyond the center of gravity of the robot chassis to raise the forward end of the robot chassis and invert the robot endwise. |
FILED | Friday, April 01, 2011 |
APPL NO | 13/078618 |
ART UNIT | 3611 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Motor vehicles 180/9.320 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075223 | Ansay et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael T. Ansay (Johnston, Rhode Island); Angelo Di Biasio (Narragansett, Rhode Island); Mariela I. Santiago (Portsmouth, Rhode Island); Robert W. Goldman (Portmouth, Rhode Island) |
ABSTRACT | A system for deploying a fiber optic line sensor is provided that includes a launch vehicle to which three sections are attached. The first section is a buoy antenna section. The second section is an electronics canister section having control electronics. These sections are releasably attached to the launch vehicle. The electronics canister section is in contact with the antenna section and secured to the antenna section by a spring band. A communications cable is attached between the antenna and the control electronics. The third section is a spool section containing a spool of a fiber optic line sensor. This third section is attached to the launch vehicle by a rigid mount and is in contact with the electronics canister section. The fiber optic line sensor extends from the spool section into the electronics canister section to the control electronics. |
FILED | Friday, March 27, 2009 |
APPL NO | 12/386185 |
ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Hydraulic and earth engineering 45/158 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075799 | Hong et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | South Dakota School of Mines and Technology (Rapid City, South Dakota) |
INVENTOR(S) | Haiping Hong (Rapid City, South Dakota); Jesse Wensel (Boise, Idaho) |
ABSTRACT | The present invention relates to a nanofluid that contains carbon nanoparticles, metal oxide nanoparticles and a surfactant in a thermal transfer fluid. The present invention also relates to processes for producing such a nanofluid with enhanced thermal conductive properties. |
FILED | Tuesday, June 05, 2007 |
APPL NO | 11/810303 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Compositions 252/70 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076079 | Frasch et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Arizona Board of Regents, a body coporate acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Wayne Frasch (Phoenix, Arizona); Lyian He (Chandler, Arizona) |
ABSTRACT | The present invention provides methods and compositions for highly sensitive nucleic acid detection, down to the single nucleic acid molecule level. In one aspect, the present invention provides methods for detecting a target nucleic acid comprising: (a) providing first and second target-specific nucleic acids, wherein the first and second target-specific nucleic acids each comprise sequences complementary to the target nucleic acid; wherein the first target specific nucleic acid is bound to a first affinity tag and the second target-specific nucleic acid is bound to a second affinity tag, wherein the first affinity tag is capable of binding to a molecular motor, and wherein the second affinity tag is capable of binding to a detection probe; (b) contacting the first and second target-specific nucleic acids to a sample under conditions whereby the first and second target-specific nucleic acids will hybridize to the target nucleic acid if the target nucleic acid is present in the sample, wherein upon hybridization to the target nucleic acid the first and second target-specific nucleic acids are directly adjacent to each other; (c) ligating the first and second target-specific nucleic acids together; (d) binding the molecular motor t˜ the first affinity tag and the detection probe to the second affinity tag; (e) inducing movement of the molecular motor; and (f) detecting movement of the molecular motor through the detection probe, wherein the movement of the molecular motor serves to detect the target nucleic acid in the sample. |
FILED | Friday, December 17, 2004 |
APPL NO | 10/582820 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076150 | Genovese |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | James A. Genovese (Street, Maryland) |
ABSTRACT | Methods and apparatus for chemical warfare agent detection training are provided. More particularly, methods and apparatus are provided to simulate the detection of low volatility chemical warfare agents by simulating the use of currently fielded U.S. Army detection kits without exposure to hazardous agents. A simulant is disposed in a sample heating assembly. The sample heating assembly is placed over a detection window of a detector, and the simulant is heated in order to make a simulated detection. |
FILED | Wednesday, June 30, 2010 |
APPL NO | 12/826816 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/104 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076178 | Krishnamoorthy et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Oracle America, Inc. (Redwood Shores, California) |
INVENTOR(S) | Ashok V. Krishnamoorthy (San Diego, California); John E. Cunningham (San Diego, California); James G. Mitchell (Palo Alto, California) |
ABSTRACT | Embodiments of a method for assembling a multi-chip module (MCM) are described. During this method, a fluid that includes coupling elements is applied to a surface of a base plate in the MCM. Then, at least some of the coupling elements are positioned into negative features on the surface of the base plate using fluidic assembly. Note that a given coupling element selects a given negative feature using chemical-based selection and/or geometry-based selection. Next, the fluid and excess coupling elements (which reside in regions outside of the negative features on the surface) are removed. |
FILED | Friday, September 28, 2007 |
APPL NO | 11/864369 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/107 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076467 | Niu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Research Foundation of State University of New York (Albany, New York); Cornell University (Ithaca, New York) |
INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Albany, New York); Hua Shi (Ithaca, New York); John T. Lis (Ithaca, New York) |
ABSTRACT | The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors. |
FILED | Tuesday, October 13, 2009 |
APPL NO | 12/578231 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076496 | Saxon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Eliana Saxon (Albany, California); Carolyn Ruth Bertozzi (Berkeley, California) |
ABSTRACT | The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). |
FILED | Tuesday, March 08, 2011 |
APPL NO | 13/043274 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 552/10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076662 | Ramanathan et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Shriram Ramanathan (Acton, Massachusetts); Changhun Ko (Cambridge, Massachusetts) |
ABSTRACT | Phase transitions (such as metal-insulator transitions) are induced in oxide structures (such as vanadium oxide thin films) by applying an electric field. The electric field-induced phase transitions are achieved in VO2 structures that scale down to nanometer range. In some embodiments, the optical and/or dielectric properties of the oxide structures are actively tuned by controllably varying the applied electric field. Applying a voltage to a single-phase oxide material spontaneously leads to the formation of insulating and conducting regions within the active oxide material. The dimensions and distributions of such regions can be dynamically tuned by varying the applied electric field and/or the temperature. In this way, oxide materials with dynamically tunable optical and/or dielectric properties are created. |
FILED | Friday, November 27, 2009 |
APPL NO | 12/626865 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076667 | Tansu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
INVENTOR(S) | Nelson Tansu (Bethlehem, Pennsylvania); Yik Khoon Ee (Bethlehem, Pennsylvania); James F. Gilchrist (Allentown, Pennsylvania); Pisit Kumnorkaew (Bethlehem, Pennsylvania); Ronald A. Arif (Raleigh, North Carolina) |
ABSTRACT | A tight emitting device comprises at least one p-type layer and at least one n-type layer and a microlens array surface. A method for improving light efficiency of a light emitting device, comprises depositing polystyrene microspheres by rapid convection deposition on surface of light emitting device; depositing a monolayer of close-packed SIO2 microspheres onto the polystyrene microspheres; and heal treating to convert the polystyrene microspheres into a planar microlayer film to provide a surface comprising substantially two-dimensional (2D) hexagonal close-packed SIO2 colloidal microsphere crystals partially imposed into a polystyrene monolayer film. |
FILED | Monday, December 24, 2007 |
APPL NO | 12/520619 |
ART UNIT | 2892 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076700 | Magno et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Richard Magno (Waldorf, Maryland); Mario Ancona (Alexandria, Virginia); John Bradley Boos (Springfield, Virginia); James G Champlain (Alexandria, Virginia); Harvey S Newman (Washington, District of Columbia) |
ABSTRACT | This disclosure describes a semiconductor device that can be used as a mixer at RF frequencies extending from a few tens of GHz into the THz frequency range. The device is composed of narrow bandgap semiconductors grown by solid source molecular beam epitaxy. The device can comprise a GaSb substrate, a AlSb layer on the GaSb substrate, a In0.69Al0.31As0.41Sb0.59 layer, on the AlSb layer and wherein the In0.69Al0.31As0.41Sb0.59 comprises varying levels of Te doping, a In0.27Ga0.73Sb layer on the In0.69Al0.31As0.41 Sb0.59 layer, wherein the In0.27Ga0.73Sb layer is Be doped, wherein the first section of the In0.69Al0.31As0.41Sb0.59 layer has is Te doped, wherein the second section of the In0.69Al0.31As0.41Sb0.59 layer has a grade in Te concentration, and wherein the third section of the In0.69Al0.31As0.41Sb0.59 layer is Te doped. |
FILED | Tuesday, June 02, 2009 |
APPL NO | 12/476298 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076801 | Karalis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Aristeidis Karalis (Boston, Massachusetts); Rafif E. Hamam (Cambridge, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | Disclosed is an apparatus for use in wireless energy transfer, which includes a first resonator structure configured for energy transfer with a second resonator structure over a distance D larger than characteristic sizes, L1 and L2, of the first and second resonator structures. A power generator is coupled to the first structure and configured to drive the first resonator structure or the second resonator structure at an angular frequency away from the resonance angular frequencies and shifted towards a frequency corresponding to an odd normal mode for the resonator structures to reduce radiation from the resonator structures by destructive far-field interference. |
FILED | Thursday, May 14, 2009 |
APPL NO | 12/466065 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electrical transmission or interconnection systems 37/104 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076820 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Teledyne Licensing, LLC (Thousand Oaks, California) |
INVENTOR(S) | Reh-Lin Chen (Williamsville, New York); Bing-Chung Chen (Newbury Park, California); Chung-Lung Chen (Thousand Oaks, California); Chuan-Hua Chen (Durham, North Carolina) |
ABSTRACT | An electro-osmotic pump includes a pump chamber having a wall fabricated of an electric double layer material, the surface area of the electric double layer material being high relative to the volume of the chamber. An electric potential applied across the material causes a fluid in the chamber to be transported through the wall. A nastic actuator includes the electro-osmotic pump and an actuator chamber, having a variable volume, coupled to the pump chamber. A superabsorbent polymer is disposed in the pump and actuator chambers, such that transport of the fluid into the pump chamber results in absorption of the fluid by the superabsorbent polymer, causing the actuator chamber to increase in volume. When the electric potential is applied across the superabsorbent polymer, the superabsorbent polymer expands, further causing the actuator chamber to increase in volume. |
FILED | Friday, October 05, 2007 |
APPL NO | 11/973021 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076825 | Kaajakari |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Louisiana Tech University Foundation, Inc. (Ruston, Louisiana) |
INVENTOR(S) | Ville Kaajakari (Ruston, Louisiana) |
ABSTRACT | A DC generation and storage device including a power generation section with multiple layers of an electret film. A rectifier is connected to the electret film, which in turn will be connected to a DC to DC converter. A power storage device (e.g., a battery or capacitor) will be connected to the converter. |
FILED | Monday, July 14, 2008 |
APPL NO | 12/172456 |
ART UNIT | 2839 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/339 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076881 | Hall et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Curtiss-Wright Electro-Mechanical Corp. (Chewick, Pennsylvania) |
INVENTOR(S) | David J. Hall (Pittsburgh, Pennsylvania); Mark P. Krefta (Murrysville, Pennsylvania) |
ABSTRACT | A system. The system includes a first module, a second module communicably connected to the first module, a third module communicably connected to the first module, and a fourth module communicably connected to the third module. The first module is configured for determining an angle. The angle is defined by a first rotating reference frame having an axis aligned with a permanent magnet flux of a permanent magnet motor, and a vector of a motor magnetizing flux of the permanent magnet motor. The second module is configured for defining a second rotating reference frame having an axis aligned with the vector, and for transforming a two-phase set of direct currents from the first rotating reference frame to the second rotating reference frame. The first and second rotating reference frames are synchronized. The third module is configured for generating a first direct current reference signal associated with the second rotating reference frame. The fourth module is configured for generating a second direct current reference signal associated with the second rotating reference frame. The first and second desired direct current reference signals are orthogonal. |
FILED | Tuesday, June 16, 2009 |
APPL NO | 12/485788 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Motive power systems 318/400.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076921 | Nodianos et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kristopher Nodianos (Waldorf, Maryland); Laura Blachek (Charlotte Hall, Maryland); Khoa Nguyen (Alexandria, Virginia); Adedayo Oyelowo (Alexandria, Virginia); Tan Tran (New Bern, North Carolina); Bernice Sanford (Bel Alton, Maryland); Kevin Cochran (Falls Church, Virginia) |
ABSTRACT | Systems and methods for a self-regulating power supply for MEMS thermal actuators to achieve maximum actuator displacement while preventing over powering. The present invention includes a power supply configured to regulate electrical input power to a MEMS thermal actuator in order to provide the maximum possible electrical input power. Accordingly, the present invention provides a maximum actuator displacement while preventing device failure from over powering. The present invention utilizes resistivity versus temperature properties for silicon or the like to provide a self-regulating power supply that can be utilized to power a variety of MEMS components without requiring custom actuator control circuits for each type of component. |
FILED | Thursday, September 18, 2008 |
APPL NO | 12/284475 |
ART UNIT | 2838 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Power supply or regulation systems 323/304 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077036 | Berger et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Theodore W. Berger (Rancho Palos Verdes, California); Alireza Dibazar (Los Angeles, California); Ali Yousefi (Los Angeles, California); Hyung O. Park (Torrance, California) |
ABSTRACT | A system for detecting and classifying a security breach may include at least one sensor configured to detect seismic vibration from a source, and to generate an output signal that represents the detected seismic vibration. The system may further include a controller that is configured to extract a feature vector from the output signal of the sensor and to measure one or more likelihoods of the extracted feature vector relative to set {bi} (i=1, . . . , imax) of breach classes bi. The controller may be further configured to classify the detected seismic vibration as a security breach belonging to one of the breach classes bi, by choosing a breach class within the set {bi} that has a maximum likelihood. |
FILED | Thursday, October 02, 2008 |
APPL NO | 12/244549 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/566 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077098 | Snow et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey M. Snow (Bloomington, Indiana); Michael Schumm (Bloomington, Indiana); William L. Shaff (Bedford, Indiana); Terry Carlson (Washington, Indiana); Carl Baker (Avoca, Indiana) |
ABSTRACT | A method and system are provided for testing antenna systems using position determination, orientation determination, test pattern analysis using a variety of factors and equipment including positions and orientation of antenna(s) under test at specific points and signal processing systems. |
FILED | Thursday, May 15, 2008 |
APPL NO | 12/121346 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/703 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077109 | Roberts et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts); The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Thomas M. Roberts (Bedford, Massachusetts); Scott G. Santarelli (Dracut, Massachusetts); Robert J. Mailloux (Wayland, Massachusetts) |
ABSTRACT | Methods for producing wide-band planar array antenna designs and antenna corresponding thereto. |
FILED | Monday, August 11, 2008 |
APPL NO | 12/228202 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/824 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077321 | Keith et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Gregory W Keith (Glendale, Arizona); Paul Schwerman (Phoenix, Arizona) |
ABSTRACT | One embodiment is directed to a power supply for a fiber optic gyroscope that comprises at least one main power supply, at least one demodulator local power supply to operatively couple the main power supply to a demodulator included in the fiber optic gyroscope, and at least one modulator local power supply to operatively couple the main power supply to a bias modulator included in the fiber optic gyroscope. The demodulator local power supply comprises a first current source to source current to the demodulator and a first shunt regulator coupled across a load associated with the demodulator. The modulator local power supply comprises a second current source to source current to the bias modulator and a second shunt regulator coupled across a load associated with the bias modulator. |
FILED | Friday, June 11, 2010 |
APPL NO | 12/813993 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/460 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077322 | Strandjord et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
INVENTOR(S) | Lee Strandjord (Tonka Bay, Minnesota); Norman Gerard Tarleton (Glendale, Arizona); Stephan Enzone (Tempe, Arizona) |
ABSTRACT | A resonator fiber optic gyroscope includes a first light source configured to generate a light signal. A resonator element is configured to generate an optical signal based on the light signal. A photodetector is configured to generate a first electrical signal based on the optical signal. The first electrical signal includes an oscillating signal, a direct-current (DC) signal, an even-harmonic signal including components at even harmonics of the oscillating signal, and an odd-harmonic signal including components at odd harmonics of the oscillating signal. A filtering element is configured to attenuate the DC signal, at least one even-harmonic component, and an odd-harmonic component to produce a second electrical signal. An amplifier is configured to amplify the second electrical signal. An analog-to-digital converter (ADC) is configured to digitize the amplified second electrical signal. |
FILED | Tuesday, March 31, 2009 |
APPL NO | 12/415836 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/475 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077540 | Williams |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Wahington, District of Columbia) |
INVENTOR(S) | Earl G Williams (Fairfax, Virginia) |
ABSTRACT | A system and computer implemented method for determining and displaying vector acoustic intensity fields based on signals from a rigid spherical array of acoustic sensors within a volume external to the array. The method includes a propagator with a ratio of Green's functions for the location within the volume and for the spherical array radius, and a Tikhonov regularization filter that uses the Morozov discrepancy principle on the measured noise variance and Fourier coefficients of the measured partial pressures with respect to reference accelerometer or microphone measurements. |
FILED | Monday, June 15, 2009 |
APPL NO | 12/484894 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/8 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077602 | Arimilli et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Ravi K. Arimilli (Austin, Texas); Bernard C. Drerup (Austin, Texas); Jody B. Joyner (Austin, Texas); Jerry D. Lewis (Round Rock, Texas) |
ABSTRACT | Mechanisms for performing dynamic request routing based on broadcast depth queue information are provided. Each processor chip in the system may use a synchronized heartbeat signal it generates to provide queue depth information to each of the other processor chips in the system. The queue depth information identifies a number of requests or amount of data in each of the queues of a processor chip that originated the heartbeat signal. The queue depth information from each of the processor chips in the system may be used by the processor chips in determining optimal routing paths for data from a source processor chip to a destination processor chip. As a result, the congestion of data for processing at each of the processor chips along each possible routing path may be taken into account when selecting to which processor chip to forward data. |
FILED | Friday, February 01, 2008 |
APPL NO | 12/024514 |
ART UNIT | 2466 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/217 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077747 | Schulzgen et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
INVENTOR(S) | Axel Schulzgen (Tucson, Arizona); Jacques Albert (Gatineau, Canada); Nasser Peyghambarian (Tucson, Arizona); Seppo Honkanen (Tucson, Arizona); Li Li (Tucson, Arizona) |
ABSTRACT | An optical device includes an optical fiber having a core including multicomponent phosphate glasses, and a cladding surrounding the core, and a first fiber Bragg grating formed in a first portion of the core of the optical fiber and having an index modulation amplitude greater than 2×10−5. |
FILED | Wednesday, September 26, 2007 |
APPL NO | 11/861923 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077958 | Qian et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Wei Qian (Wesley Chapel, Florida); Dansheng Song (Tampa, Florida); Tatyana A. Zhukov (Lutz, Florida) |
ABSTRACT | The present invention is a computer-aided pathological diagnosis method for the classification of cancer cells in a tissue specimen based on a digital cellular image of the tissue specimen. The method of the present invention includes the steps of, extracting the histological characteristic features of the cellular image using preprocessing algorithms having adaptive strategies to enhance the cellular image, declustering the extracted histological characteristic features of the cellular image to isolate the individual cells and the nuclei inside the cells, segmenting the declustered cellular image, labeling the segmented cellular image and classifying the cells in the labeled cellular image as cancer cells or non-cancer cells. |
FILED | Monday, July 02, 2007 |
APPL NO | 11/772288 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/133 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078004 | Kang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
INVENTOR(S) | Yong Q. Kang (Elkton, Maryland); Young-Heon Jo (Camden, Delaware); Xiao-Hai Yan (Newark, Delaware) |
ABSTRACT | A method for registering a first image to a second image using a similarity transformation. The each image includes a plurality of pixels. The first image pixels are mapped to a set of first image coordinates and the second image pixels are mapped to a set of second image coordinates. The first image coordinates of two reference points in the first image are determined. The second image coordinates of these reference points in the second image are determined. A Cartesian translation of the set of second image coordinates is performed such that the second image coordinates of the first reference point match its first image coordinates. A similarity transformation of the translated set of second image coordinates is performed. This transformation scales and rotates the second image coordinates about the first reference point such that the second image coordinates of the second reference point match its first image coordinates. |
FILED | Monday, November 05, 2007 |
APPL NO | 11/935012 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/276 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078013 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Oracle America, Inc. (Redwood Shores, California) |
INVENTOR(S) | Guoliang Li (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California); Ivan Shubin (San Diego, California); Xuezhe Zheng (San Diego, California) |
ABSTRACT | Embodiments of an optical device, an array of optical devices, and a technique for fabricating the optical device or the array are described. This optical device is implemented using two semiconductor layers (such as silicon), one of which includes a heater and the other includes a thermally tunable optical waveguide. Spatially separating these two functions in the optical device results in more efficient heat transfer between the heater and the optical waveguide, reduced heat transfer to the surroundings, and reduced optical losses in the optical waveguide relative to existing silicon-based optical devices. |
FILED | Tuesday, March 31, 2009 |
APPL NO | 12/415886 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical waveguides 385/1 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078020 | Rasras |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Alcatel Lucent (Paris, France) |
INVENTOR(S) | Mahmoud Rasras (Berkeley Heights, New Jersey) |
ABSTRACT | An apparatus comprising an optical-mode-converter structure. The optical-mode-converter structure includes a tapered optical core on a planar substrate, an optical cladding layer covering the tapered optical core and a mode-expanding layer. The mode-expanding layer covers the tapered optical core and is located in-between the tapered optical core and the optical cladding layer. The mode-expanding layer has a refractive index that is in-between a refractive index of the tapered optical core and a refractive index of the optical cladding layer. |
FILED | Tuesday, April 08, 2008 |
APPL NO | 12/099200 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/28 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078292 | Fuller |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | James W. Fuller (Amston, Connecticut) |
ABSTRACT | A method of estimating a basepoint includes receiving a plurality of goals, wherein each goal has a desired value, and receiving a plurality of sensor feedback signals from a controlled system. A plurality of predicted output values of the controlled system are received from a mathematical model. A desired change for a plurality of basepoint values is estimated in response to the goals, the feedback, and the predicted output values. An actual change in basepoint values is calculated in response to a plurality of limits and the desired change for the plurality of basepoint values according to a plurality of goal weights while holding limits. The actual change in basepoint values is combined with last pass values of the plurality of basepoint values to produce an updated basepoint estimate. |
FILED | Tuesday, July 08, 2008 |
APPL NO | 12/169183 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Generic control systems or specific applications 7/31 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078832 | Agarwal et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Anant Agarwal (Weston, Massachusetts); David Wentzlaff (Cambridge, Massachusetts) |
ABSTRACT | An integrated circuit includes a plurality of processor core. Processing instructions in the integrated circuit includes: managing a plurality of sets of processor cores, each set including one or more processor cores assigned to a function associated with executing instructions; and reconfiguring the number of processor cores assigned to at least one of the sets during execution based on characteristics associated with executing the instructions. |
FILED | Wednesday, May 28, 2008 |
APPL NO | 12/128073 |
ART UNIT | 2183 — Computer Architecture and I/O |
CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 08074490 | Andrews, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | William H. Andrews, Jr. (Oliver Springs, Tennessee); Cyril V. Thompson (Knoxville, Tennessee); Arpad A. Vass (Oak Ridge, Tennessee); Rob R. Smith (Knoxville, Tennessee) |
ABSTRACT | An apparatus and a method for detecting a burial site of human remains are disclosed. An air stream is drawn through an air intake conduit from locations near potential burial sites of human remains. The air stream is monitored by one or more chemical sensors to determine whether the air stream includes one or more indicator compounds selected from halogenated compounds, hydrocarbons, nitrogen-containing compounds, sulfur-containing compounds, acid/ester compounds, oxygen-containing compounds, and naphthalene-containing compounds. When it is determined that an indicator compound is present in the air stream, this indicates that a burial site of human remains is below or nearby. Each sensor may be in electrical communication with an indicator that signals when the sensor has detected the presence of the indicator compound in the air stream. In one form, the indicator compound is a halogenated compound and/or a hydrocarbon, and the presence of the halogenated compound and/or the hydrocarbon in the air stream indicates that a burial site of human remains is below or nearby. |
FILED | Thursday, August 03, 2006 |
APPL NO | 11/498705 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/31.50 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08074505 | Foster et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David E. Foster (Middleton, Wisconsin); Ekathai Wirojsakunchai (Madison, Wisconsin); Christopher P. Kolodziej (Stevens Point, Wisconsin); Renato A. Yapaulo (Madison, Wisconsin) |
ABSTRACT | A system for analyzing a substrate material for a diesel or other internal combustion engine exhaust filtration performance includes a valve that actuates within an exhaust system to modulate engine exhaust back pressure and correspondingly maintain a desired filtration velocity to influence a variable parameter within the system, based at least in part on an exhaust characteristic such as a sensed exhaust pressure differential defined across a substrate material. |
FILED | Wednesday, July 09, 2008 |
APPL NO | 12/169819 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/114.690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08074614 | Marriott et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
INVENTOR(S) | Craig D. Marriott (Clawson, Michigan); Timothy L. Neal (Ortonville, Michigan); Jeff L. Swain (Flushing, Michigan); Miguel A. Raimao (Colorado Springs, Colorado) |
ABSTRACT | An engine assembly may include a cylinder head defining an engine coolant reservoir, a pressurized fluid supply, a valve actuation assembly, and a hydraulic fluid reservoir. The valve actuation assembly may be in fluid communication with the pressurized fluid supply and may include a valve member displaceable by a force applied by the pressurized fluid supply. The hydraulic fluid reservoir may be in fluid communication with the valve actuation assembly and in a heat exchange relation to the engine coolant reservoir. |
FILED | Friday, September 12, 2008 |
APPL NO | 12/209580 |
ART UNIT | 3748 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Internal-combustion engines 123/90.120 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08074895 | Mao et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Delavan Inc (West Des Moines, Iowa) |
INVENTOR(S) | Chien-Pei Mao (Clive, Iowa); John Short (Norwalk, Iowa); Jim Klemm (Des Moines, Iowa); Royce Abbott (Des Moines, Iowa); Nick Overman (West Des Moines, Iowa); Spencer Pack (Urbandale, Iowa); Audra Winebrenner (Des Moines, Iowa) |
ABSTRACT | A fuel injection and mixing system is provided that is suitable for use with various types of fuel reformers. Preferably, the system includes a piezoelectric injector for delivering atomized fuel, a gas swirler, such as a steam swirler and/or an air swirler, a mixing chamber and a flow mixing device. The system utilizes ultrasonic vibrations to achieve fuel atomization. The fuel injection and mixing system can be used with a variety of fuel reformers and fuel cells, such as SOFC fuel cells. |
FILED | Wednesday, April 11, 2007 |
APPL NO | 11/734260 |
ART UNIT | 3752 — Fluid Handling and Dispensing |
CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/102.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075256 | Little |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
INVENTOR(S) | David A. Little (Chuluota, Florida) |
ABSTRACT | A seal assembly limits gas leakage from a hot gas path to one or more disc cavities in a gas turbine engine. The seal assembly includes a seal apparatus associated with a blade structure including a row of airfoils. The seal apparatus includes an annular inner shroud associated with adjacent stationary components, a wing member, and a first wing flange. The wing member extends axially from the blade structure toward the annular inner shroud. The first wing flange extends radially outwardly from the wing member toward the annular inner shroud. A plurality of regions including one or more recirculation zones are defined between the blade structure and the annular inner shroud that recirculate working gas therein back toward the hot gas path. |
FILED | Wednesday, April 29, 2009 |
APPL NO | 12/432061 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Rotary kinetic fluid motors or pumps 415/173.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075642 | Dumesic et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | James A. Dumesic (Verona, Wisconsin); Dante A. Simonetti (Middleton, Wisconsin); Edward L. Kunkes (Madison, Wisconsin) |
ABSTRACT | Disclosed is a method for preparing liquid fuel and chemical intermediates from biomass-derived oxygenated hydrocarbons. The method includes the steps of reacting in a single reactor an aqueous solution of a biomass-derived, water-soluble oxygenated hydrocarbon reactant, in the presence of a catalyst comprising a metal selected from the group consisting of Cr, Mn, Fe, Co, Ni, Cu, Mo, Tc, Ru, Rh, Pd, Ag, W, Re, Os, Ir, Pt, and Au, at a temperature, and a pressure, and for a time sufficient to yield a self-separating, three-phase product stream comprising a vapor phase, an organic phase containing linear and/or cyclic mono-oxygenated hydrocarbons, and an aqueous phase. |
FILED | Monday, April 14, 2008 |
APPL NO | 12/102223 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Fuel and related compositions 044/308 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075664 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Haorong Wang (Albuquerque, New Mexico); Yujiang Song (Albuquerque, New Mexico); John A. Shelnutt (Tijeras, New Mexico); Craig J. Medforth (Winters, California) |
ABSTRACT | Metal nanostructures formed by photocatalytic interfacial synthesis using a porphyrin-stabilized emulsion template and the method for making the nanostructures. Catalyst-seeded emulsion droplets are employed as templates for hollow-nanoshell growth. The hollow metal nanospheres may be formed with or without inclusions of other materials. |
FILED | Monday, June 11, 2007 |
APPL NO | 11/760850 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/370 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075712 | Farmer |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Joseph C. Farmer (Tracy, California) |
ABSTRACT | A system for coating a surface comprising providing a source of amorphous metal that contains more than 11 elements and applying the amorphous metal that contains more than 11 elements to the surface by a spray. Also a coating comprising a composite material made of amorphous metal that contains more than 11 elements. An apparatus for producing a corrosion-resistant amorphous-metal coating on a structure comprises a deposition chamber, a deposition source in the deposition chamber that produces a deposition spray, the deposition source containing a composite material made of amorphous metal that contains more than 11 elements, and a system that directs the deposition spray onto the structure. |
FILED | Monday, November 13, 2006 |
APPL NO | 11/598940 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Metal treatment 148/403 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075716 | Simpson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Randall L. Simpson (Livermore, California); Ronald S. Lee (Livermore, California); Thomas M. Tillotson (Tracy, California); Lawrence W. Hrubesh (Pleasanton, California); Rosalind W. Swansiger (Livermore, California); Glenn A. Fox (Livermore, California) |
ABSTRACT | Sol-gel chemistry is used for the preparation of energetic materials (explosives, propellants and pyrotechnics) with improved homogeneity, and/or which can be cast to near-net shape, and/or made into precision molding powders. The sol-gel method is a synthetic chemical process where reactive monomers are mixed into a solution, polymerization occurs leading to a highly cross-linked three dimensional solid network resulting in a gel. The energetic materials can be incorporated during the formation of the solution or during the gel stage of the process. The composition, pore, and primary particle sizes, gel time, surface areas, and density may be tailored and controlled by the solution chemistry. The gel is then dried using supercritical extraction to produce a highly porous low density aerogel or by controlled slow evaporation to produce a xerogel. Applying stress during the extraction phase can result in high density materials. Thus, the sol-gel method can be used for precision detonator explosive manufacturing as well as producing precision explosives, propellants, and pyrotechnics, along with high power composite energetic materials. |
FILED | Tuesday, January 11, 2000 |
APPL NO | 09/481043 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosive and thermic compositions or charges 149/19.920 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075758 | Joshi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
INVENTOR(S) | Ashok V. Joshi (Salt Lake City, Utah); Shekar Balagopal (Sandy, Utah); Justin Pendelton (Salt Lake City, Utah) |
ABSTRACT | Alkali alcoholates, also called alkali alkoxides, are produced from alkali metal salt solutions and alcohol using a three-compartment electrolytic cell. The electrolytic cell includes an anolyte compartment configured with an anode, a buffer compartment, and a catholyte compartment configured with a cathode. An alkali ion conducting solid electrolyte configured to selectively transport alkali ions is positioned between the anolyte compartment and the buffer compartment. An alkali ion permeable separator is positioned between the buffer compartment and the catholyte compartment. The catholyte solution may include an alkali alcoholate and alcohol. The anolyte solution may include at least one alkali salt. The buffer compartment solution may include a soluble alkali salt and an alkali alcoholate in alcohol. |
FILED | Thursday, December 14, 2006 |
APPL NO | 11/611054 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/450 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075792 | Branz et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Howard Branz (Boulder, Colorado); Anna Duda (Denver, Colorado); David S. Ginley (Evergreen, Colorado); Vernon Yost (Littleton, Colorado); Daniel Meier (Atlanta, Georgia); James S. Ward (Golden, Colorado) |
ABSTRACT | A method (300) of texturing silicon surfaces (116) such to reduce reflectivity of a silicon wafer (110) for use in solar cells. The method (300) includes filling (330, 340) a vessel (122) with a volume of an etching solution (124) so as to cover the silicon surface 116) of a wafer or substrate (112). The etching solution (124) is made up of a catalytic nanomaterial (140) and an oxidant-etchant solution (146). The catalytic nanomaterial (140) may include gold or silver nanoparticles or noble metal nanoparticles, each of which may be a colloidal solution. The oxidant-etchant solution (146) includes an etching agent (142), such as hydrofluoric acid, and an oxidizing agent (144), such as hydrogen peroxide. Etching (350) is performed for a period of time including agitating or stirring the etching solution (124). The etch time may be selected such that the etched silicon surface (116) has a reflectivity of less than about 15 percent such as 1 to 10 percent in a 350 to 1000 nanometer wavelength range. |
FILED | Friday, March 21, 2008 |
APPL NO | 12/053372 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Etching a substrate: Processes 216/89 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076031 | West et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Robert C. West (Madison, Wisconsin); Khalil Amine (Downers Grove, Illinois); Zhengcheng Zhang (Monona, Wisconsin); Qingzheng Wang (Bolingbrook, Illinois); Nicholas Agostino Antonio Rossi (Madison, Wisconsin); Donald R. Vissers (Naperville, Illinois) |
ABSTRACT | One example of the disiloxanes include a backbone with a first silicon and a second silicon. The first silicon is linked to a first substituent selected from a group consisting of: a first side chain that includes a cyclic carbonate moiety; a first side chain that includes a poly(alkylene oxide) moiety; and a first cross link links the disiloxane to a second siloxane and that includes a poly(alkylene oxide) moiety. In some instance, the second silicon is linked to a second substituent selected from a group consisting of: a second side chain that includes a cyclic carbonate moiety, and a second side chain that includes a poly(alkylene oxide) moiety. |
FILED | Thursday, February 10, 2005 |
APPL NO | 11/056866 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076032 | West et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Robert C. West (Madison, Wisconsin); Khalil Amine (Downers Grove, Illinois); Zhengcheng Zhang (Monona, Wisconsin); Qingzheng Wang (Bolingbrook, Illinois); Nicholas A. A. Rossi (Madison, Wisconsin); Sang Young Yoon (Saugus, California); Hiroshi Nakahara (Santa Clarita, California) |
ABSTRACT | The electrolyte includes one or more salts and a silane. The silane has a silicon linked to one or more first substituents that each include a poly(alkylene oxide) moiety or a cyclic carbonate moiety. The silane can be linked to four of the first substituents. Alternately, the silane can be linked to the one or more first substituents and one or more second substituents that each exclude both a poly(alkylene oxide) moiety and a cyclic carbonate moiety. |
FILED | Thursday, February 10, 2005 |
APPL NO | 11/056869 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076034 | Lassila et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | David H. Lassila (Aptos, California); Brian P. Bonner (Livermore, California) |
ABSTRACT | A high pressure hydrogen confinement apparatus according to one embodiment includes carbon nanotubes capped at one or both ends thereof with a hydrogen-permeable membrane to enable the high pressure confinement of hydrogen and release of the hydrogen therethrough. A hydrogen confinement apparatus according to another embodiment includes an array of multi-walled carbon nanotubes each having first and second ends, the second ends being capped with palladium (Pd) to enable the high pressure confinement of hydrogen and release of the hydrogen therethrough as a function of palladium temperature, wherein the array of carbon nanotubes is capable of storing hydrogen gas at a pressure of at least 1 GPa for greater than 24 hours. Additional apparatuses and methods are also presented. |
FILED | Thursday, September 18, 2008 |
APPL NO | 12/233388 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076124 | McKnight et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Timothy E. McKnight (Greenback, Tennessee); Anatoli V. Melechko (Oak Ridge, Tennessee); Michael L. Simpson (Knoxville, Tennessee) |
ABSTRACT | A method for the transient transformation of a living biological cell having an intact cell membrane defining an intracellular domain, and an apparatus for the transient transformation of biological cells. The method and apparatus include introducing a compartmentalized extracellular component fixedly attached to a cellular penetrant structure to the intracellular domain of the cell, wherein the cell is fixed in a predetermined location and wherein the component is expressed within in the cell while being retained within the compartment and wherein the compartment restricts the mobility and interactions of the component within the cell and prevents transference of the component to the cell. |
FILED | Wednesday, January 17, 2007 |
APPL NO | 11/624040 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/285.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076382 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Luping Yu (Hoffman Estates, Illinois); Di-Jia Liu (Naperville, Illinois); Shengwen Yuan (Chicago, Illinois); Junbing Yang (Westmont, Illinois) |
ABSTRACT | Porous polymers, tribenzohexazatriphenylene, poly-9,9′-spirobifluorene, poly-tetraphenyl methane and their derivatives for storage of H2 prepared through a chemical synthesis method. The porous polymers have high specific surface area and narrow pore size distribution. Hydrogen uptake measurements conducted for these polymers determined a higher hydrogen storage capacity at the ambient temperature over that of the benchmark materials. The method of preparing such polymers, includes oxidatively activating solids by CO2/steam oxidation and supercritical water treatment. |
FILED | Friday, June 27, 2008 |
APPL NO | 12/215653 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 521/61 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076485 | Bar-Or et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Institute for Molecular Medicine, Inc. (Englewood, Colorado) |
INVENTOR(S) | David Bar-Or (Englewood, Colorado); Nagaraja K. R. Rao (Cardiff, United Kingdom) |
ABSTRACT | The present invention provides methods of using compounds of formula I: and salts and prodrugs thereof, wherein n, R1 and R2 are defined herein. The invention also provides certain novel compounds of formula I and pharmaceutical compositions comprising them. |
FILED | Wednesday, October 29, 2008 |
APPL NO | 12/260964 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/227 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076496 | Saxon et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Eliana Saxon (Albany, California); Carolyn Ruth Bertozzi (Berkeley, California) |
ABSTRACT | The present invention features a chemoselective ligation reaction that can be carried out under physiological conditions. In general, the invention involves condensation of a specifically engineered phosphine, which can provide for formation of an amide bond between the two reactive partners resulting in a final product comprising a phosphine moiety, or which can be engineered to comprise a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine byproduct and producing a native amide bond in the final product. The selectivity of the reaction and its compatibility with aqueous environments provides for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). |
FILED | Tuesday, March 08, 2011 |
APPL NO | 13/043274 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 552/10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076617 | Norwood et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Robert A. Norwood (Tucson, Arizona); Terje Skotheim (Tucson, Arizona) |
ABSTRACT | Provided is a tunable radiation emitting structure comprising: a nanoamorphous carbon structure having a plurality of relief features provided in a periodic spatial configuration, wherein the relief features are separated from each other by adjacent recessed features, and wherein the nanoamorphous carbon comprises a total of from 0 to 60 atomic percent of one or more dopants of the dopant group consisting of: transition metals, lanthanoids, electro-conductive carbides, silicides and nitrides. In one embodiment, a dopant is selected from the group consisting of: Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, La and other lanthanides, Hf, Ta, W, Rh, Os, Ir, Pt, Au, and Hg. In one embodiment, a dopant is selected from the group consisting of: electro-conductive carbides (like Mo2C), silicides (like MoSi2) and nitrides (like TiN). |
FILED | Monday, April 07, 2008 |
APPL NO | 12/098708 |
ART UNIT | 3742 — Organic Chemistry |
CURRENT CPC | Electric heating 219/407 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077047 | Humble et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Ut-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Travis S. Humble (Knoxville, Tennessee); Ryan S. Bennink (Knoxville, Tennessee); Warren P. Grice (Oak Ridge, Tennessee) |
ABSTRACT | The use of quantum-mechanically entangled photons for monitoring the integrity of a physical border or a communication link is described. The no-cloning principle of quantum information science is used as protection against an intruder's ability to spoof a sensor receiver using a ‘classical’ intercept-resend attack. Correlated measurement outcomes from polarization-entangled photons are used to protect against quantum intercept-resend attacks, i.e., attacks using quantum teleportation. |
FILED | Thursday, April 16, 2009 |
APPL NO | 12/424957 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Communications: Electrical 340/600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077754 | Williamson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Rodney L. Williamson (Albuquerque, New Mexico); David K. Melgaard (Albuquerque, New Mexico); Joseph J. Beaman (Austin, Texas) |
ABSTRACT | An apparatus for and method of controlling a remelting furnace comprising adjusting current supplied to an electrode based upon a predetermined pool power reference value and adjusting the electrode drive speed based upon the predetermined pool power reference value. |
FILED | Tuesday, August 08, 2006 |
APPL NO | 11/501198 |
ART UNIT | 3742 — Semiconductors/Memory |
CURRENT CPC | Industrial electric heating furnaces 373/102 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078060 | Wilcox et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
INVENTOR(S) | Russell B. Wilcox (El Cerrito, California); Ronald Holzwarth (Munich, Germany) |
ABSTRACT | Femtosecond pump/probe experiments using short X-Ray and optical pulses require precise synchronization between 100 meter-10 km separated lasers in a various experiments. For stabilization in the hundred femtosecond range a CW laser is amplitude modulated at 1-10 GHz, the signal retroreflected from the far end, and the relative phase used to correct the transit time with various implementations. For the sub-10 fsec range the laser frequency itself is upshifted 55 MHz with an acousto-optical modulator, retroreflected, upshifted again and phase compared at the sending end to a 110 MHz reference. Initial experiments indicate less than 1 fsec timing jitter. To lock lasers in the sub-10 fs range two single-frequency lasers separated by several teraHertz will be lock to a master modelocked fiber laser, transmit the two frequencies over fiber, and lock two comb lines of a slave laser to these frequencies, thus synchronizing the two modelocked laser envelopes. |
FILED | Wednesday, April 04, 2007 |
APPL NO | 11/696591 |
ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Optical communications 398/154 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078162 | Deaton et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Juan D. Deaton (Menan, Idaho); Michael J. Schmitt (Idaho Falls, Idaho); Warren F. Jones (Idaho Falls, Idaho) |
ABSTRACT | An airborne wireless communication system includes circuitry configured to access information describing a configuration of a terrestrial wireless communication base station that has become disabled. The terrestrial base station is configured to implement wireless communication between wireless devices located within a geographical area and a network when the terrestrial base station is not disabled. The circuitry is further configured, based on the information, to configure the airborne station to have the configuration of the terrestrial base station. An airborne communication method includes answering a 911 call from a terrestrial cellular wireless phone using an airborne wireless communication system. |
FILED | Wednesday, October 10, 2007 |
APPL NO | 11/870357 |
ART UNIT | 2617 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Telecommunications 455/431 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078389 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Westport Power Inc. (Vancouver, BC, Canada) |
INVENTOR(S) | Jian Huang (Richmond, Canada); Richard Ancimer (Columbus, Ohio); Duran Cheung (Vancouver, Canada) |
ABSTRACT | The method comprises operating a calibration engine, and collecting combustion characteristic data and reference accelerometer signals, which are correlated with each other and stored in a calibration table. The calibration table can be used by an engine to determine a real-time normal combustion characteristic when the engine is operating by collecting a real-time accelerometer sensor signal and cross correlating with the correlated data stored in the calibration table. Accordingly, the apparatus comprises a calibration engine comprising a calibration sensor, a reference accelerometer sensor and a data storage device for storing the collected calibration data that is correlated with the collected reference accelerometer signals, and an engine equipped with an accelerometer sensor, a calibration table and an electronic engine controller programmed to receive real-time accelerometer signals and cross correlate them with reference accelerometer signals to determine a real-time normal combustion characteristic. |
FILED | Wednesday, May 26, 2010 |
APPL NO | 12/788273 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/114 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 08075922 | Stamler et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Montana State University-Bozeman (Bozeman, Montana); Duke University (Durham, North Carolina) |
INVENTOR(S) | Jonathan S. Stamler (Chapel Hill, North Carolina); David J. Singel (Bozeman, Montana) |
ABSTRACT | Contrary to current opinion that nitrite in general oxidizes hemoglobin with elimination of active nitric oxide, deoxygenated hemoglobin reacts with low concentration inorganic nitrite to produce very stable iron nitrosyl hemoglobin which on delivery into the body is converted to a hemoglobin capable of nitric oxide delivery and provides vasodilator and antiplatelet activity. This provides basis for ameliorated risk blood product transfusions. |
FILED | Wednesday, December 10, 2003 |
APPL NO | 10/538404 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/718 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075951 | Hammond-Cunningham et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Paula T. Hammond-Cunningham (Newton, Massachusetts); Tarek R. Farhat (Somerville, Massachusetts) |
ABSTRACT | One aspect of the invention provides ion-exchange and gas-diffusion membranes, fabricated by a layer-by-layer approach, for use, e.g., in electrochemical cells; a process for making membrane electrode assemblies fabricated using porous frameworks, LBL composite membranes and LBL carbon-Polymer electrodes; and the application of the membrane and electrode assemblies to a variety of devices, both electrochemical and otherwise. |
FILED | Thursday, April 30, 2009 |
APPL NO | 12/433508 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating processes 427/243 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076125 | McGimpsey |
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APPLICANT(S) | |
ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
INVENTOR(S) | W. Grant McGimpsey (Boylston, Massachusetts) |
ABSTRACT | The present invention is directed, at least in part, to methods for imagewise patterning of a surface. Such patterned surfaces can be used, e.g., in microfluidic devices. Accordingly, the present invention is also directed, at least in part, to nanopatterned devices which include a microchannel structure and methods for forming such devices. |
FILED | Wednesday, November 15, 2006 |
APPL NO | 12/093519 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/285.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076141 | Jackson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | E.I. du Pont de Nemours and Company (Wilmington, Delaware); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
INVENTOR(S) | David Peter Jackson (New York, New York); Namiko Satoh Nagasawa (Huntington, New York); Hajime Sakai (Newark, Delaware); Nobuhiro Nagasawa (Akita, Japan) |
ABSTRACT | The invention relates to the isolation and characterization of a maize gene, RAMOSA3 (RA3), responsible for meristem development and inflorescence development including branching. The gene, gene product, and regulatory regions may be used to manipulate branching, meristem growth, inflorescence development and arrangement, and ultimately to improve yield of plants. The invention includes the gene and protein product as well as the use of the same for temporal and spatial expression in transgenic plants to alter plant morphology and affect yield in plants. The invention also includes the gene and protein product for SISTER OF RAMOSA3 (SRA). |
FILED | Tuesday, March 08, 2011 |
APPL NO | 13/042531 |
ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/468 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076451 | Reshetnyak et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Board of Governors for Higher Education, State of Rhode Island and Providence Plantations (Providence, Rhode Island); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Yana K. Reshetnyak (South Kingstown, Rhode Island); Oleg A. Andreev (South Kingstown, Rhode Island); Ursula Lehnert (Richmond, United Kingdom); Donald M. Engelman (New Haven, Connecticut) |
ABSTRACT | A polypeptide with a predominantly hydrophobic sequence long enough to span a membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more dissociable groups inserts across a membrane spontaneously in a pH-dependant fashion placing one terminus inside cell. The polypeptide conjugated with various functional moieties delivers and accumulates them at cell membrane with low extracellular pH. The functional moiety conjugated with polypeptide terminus placed inside cell are translocated through the cell membrane in cytosol. The peptide and its variants or non-peptide analogs can be used to deliver therapeutic, prophylactic, diagnostic, imaging, gene regulation, cell regulation, or immunologic agents to or inside of cells in vitro or in vivo in tissue at low extracellular pH. The claimed method provides a new approach for diagnostic and treatment diseases with naturally occurred (or artificially created) low pH extracellular environment such as tumors, infarction, stroke, atherosclerosis, inflammation, infection, or trauma. The method allows to translocate cell impermeable molecules (peptides, toxins, drugs, inhibitors, nucleic acids, peptide nucleic acids, imaging probes) into cells at low pH. The method allows to attach to the cell surface a variety of functional moieties and particles including peptides, polysaccharides, virus, antigens, liposomes and nanoparticles made of any materials. |
FILED | Monday, July 16, 2007 |
APPL NO | 11/778323 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076667 | Tansu et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
INVENTOR(S) | Nelson Tansu (Bethlehem, Pennsylvania); Yik Khoon Ee (Bethlehem, Pennsylvania); James F. Gilchrist (Allentown, Pennsylvania); Pisit Kumnorkaew (Bethlehem, Pennsylvania); Ronald A. Arif (Raleigh, North Carolina) |
ABSTRACT | A tight emitting device comprises at least one p-type layer and at least one n-type layer and a microlens array surface. A method for improving light efficiency of a light emitting device, comprises depositing polystyrene microspheres by rapid convection deposition on surface of light emitting device; depositing a monolayer of close-packed SIO2 microspheres onto the polystyrene microspheres; and heal treating to convert the polystyrene microspheres into a planar microlayer film to provide a surface comprising substantially two-dimensional (2D) hexagonal close-packed SIO2 colloidal microsphere crystals partially imposed into a polystyrene monolayer film. |
FILED | Monday, December 24, 2007 |
APPL NO | 12/520619 |
ART UNIT | 2892 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076701 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Zhong L. Wang (Marietta, Georgia); Christopher J. Summers (Dunwoody, Georgia); Xudong Wang (Atlanta, Georgia); Elton D Graugnard (Atlanta, Georgia); Jeffrey King (Atlanta, Georgia) |
ABSTRACT | A method of making nanostructures using a self-assembled monolayer of organic spheres is disclosed. The nanostructures include bowl-shaped structures and patterned elongated nanostructures. A bowl-shaped nanostructure with a nanorod grown from a conductive substrate through the bowl-shaped nanostructure may be configured as a field emitter or a vertical field effect transistor. A method of separating nanoparticles of a desired size employs an array of bowl-shaped structures. |
FILED | Friday, February 08, 2008 |
APPL NO | 12/028218 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/213 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076800 | Joannopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
ABSTRACT | The electromagnetic energy transfer device includes a first resonator structure receiving energy from an external power supply. The first resonator structure has a first Q-factor. A second resonator structure is positioned distal from the first resonator structure, and supplies useful working power to an external load. The second resonator structure has a second Q-factor. The distance between the two resonators can be larger than the characteristic size of each resonator. Non-radiative energy transfer between the first resonator structure and the second resonator structure is mediated through coupling of their resonant-field evanescent tails. |
FILED | Tuesday, March 31, 2009 |
APPL NO | 12/415655 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electrical transmission or interconnection systems 37/104 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076893 | Dong et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Jingyan Dong (Raleigh, North Carolina); Placid M. Ferreira (Champaign, Illinois) |
ABSTRACT | An electrostatic drive includes a first electrode and a second electrode responsive to a drive signal. The drive signal includes an actuation signal constituent and a sensing signal constituent. The sensing signal constituent is at a frequency higher than a natural mechanical resonant frequency of the electrostatic drive. In response to the actuation signal constituent, displacement between the first electrode and the second electrode changes, which is evaluated by detecting a change in an electrical characteristic of the drive as a function of the sensing signal constituent. |
FILED | Thursday, September 04, 2008 |
APPL NO | 12/231673 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Motive power systems 318/686 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077074 | Venkatachalam et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
INVENTOR(S) | Chandrasekaran Venkatachalam (Fort Collins, Colorado); Nitin Bharadwaj (Fort Collins, Colorado) |
ABSTRACT | Certain embodiments provide a network waveform system that can include multiple radars disposed at different geographical positions within an environment. The multiple radars may be configured to transmit a network waveform. The network waveform may include multiple radar waveforms. Each radar waveform of the multiple waveforms may be transmitted by a specific radar of the multiple radars. The system can also include a computer system coupled with the multiple radars that can include a processor and a memory. The memory may be configured to store information including data received from the multiple radars, data processed by the processor, and processing code executable by the processor. The processing code may include instructions to receive output data from the multiple radars resulting from the transmitted network waveform instructions to jointly process the output data from the multiple radars to determine a measurement of the environment based on the network waveform. |
FILED | Thursday, May 07, 2009 |
APPL NO | 12/387845 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/59 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077101 | Mastarone, Jr. et al. |
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APPLICANT(S) | |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | John F. Mastarone, Jr. (Arlington, Virginia); William J. Chappell (Lafayette, Indiana) |
ABSTRACT | Methods and apparatus that provide grade-level RF transceivers for use in trans-grade wireless communication networks. The methods involve incorporating slot antennas into grade-level opening covers, such as manhole covers, to provide built-in antennas for transceivers that may be connected by transmission lines. The grade-level transceivers use coupling mechanisms to connect transceivers to the slot antennas by way of transmission feed lines. Multi-slot grade-level transceivers use switching mechanisms to switch between multiple slot antennas. Certain embodiments may also include adaptable RF circuitry. Trans-grade wireless communication networks use these grade-level transceivers to communicate between below-ground and above-ground portions of the network, which may be used in underground utility systems such as combined sewer systems. |
FILED | Wednesday, February 07, 2007 |
APPL NO | 11/672282 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/719 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077937 | Niogi et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Sumit Narayan Niogi (New York, New York); Bruce D. McCandliss (New York, New York) |
ABSTRACT | The invention provides a reproducible, objective quantification technique that reliably segments white matter structures. The technique receives a seed voxel within the white matter structure from an individual, determines thresholds and selection criteria, creates a binary mask based on the at least one threshold and the at least one selection criteria and calculates the boundary of the white matter structure based on the binary mask. A magnification factor is applied to each component of the eigenvectors of voxels. Boundary voxels are determined wherein each of the boundary voxels has a magnitude above a predetermined value and is located next to a voxel having a magnitude below the predetermined value. A vector is drawn from the seed voxel to a boundary voxel and the boundary voxels are connected together, thereby forming the region of interest within the connected boundary voxels. |
FILED | Friday, November 18, 2005 |
APPL NO | 11/282270 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 08076031 | West et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Robert C. West (Madison, Wisconsin); Khalil Amine (Downers Grove, Illinois); Zhengcheng Zhang (Monona, Wisconsin); Qingzheng Wang (Bolingbrook, Illinois); Nicholas Agostino Antonio Rossi (Madison, Wisconsin); Donald R. Vissers (Naperville, Illinois) |
ABSTRACT | One example of the disiloxanes include a backbone with a first silicon and a second silicon. The first silicon is linked to a first substituent selected from a group consisting of: a first side chain that includes a cyclic carbonate moiety; a first side chain that includes a poly(alkylene oxide) moiety; and a first cross link links the disiloxane to a second siloxane and that includes a poly(alkylene oxide) moiety. In some instance, the second silicon is linked to a second substituent selected from a group consisting of: a second side chain that includes a cyclic carbonate moiety, and a second side chain that includes a poly(alkylene oxide) moiety. |
FILED | Thursday, February 10, 2005 |
APPL NO | 11/056866 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076032 | West et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Robert C. West (Madison, Wisconsin); Khalil Amine (Downers Grove, Illinois); Zhengcheng Zhang (Monona, Wisconsin); Qingzheng Wang (Bolingbrook, Illinois); Nicholas A. A. Rossi (Madison, Wisconsin); Sang Young Yoon (Saugus, California); Hiroshi Nakahara (Santa Clarita, California) |
ABSTRACT | The electrolyte includes one or more salts and a silane. The silane has a silicon linked to one or more first substituents that each include a poly(alkylene oxide) moiety or a cyclic carbonate moiety. The silane can be linked to four of the first substituents. Alternately, the silane can be linked to the one or more first substituents and one or more second substituents that each exclude both a poly(alkylene oxide) moiety and a cyclic carbonate moiety. |
FILED | Thursday, February 10, 2005 |
APPL NO | 11/056869 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076072 | McGall et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Affymetrix, Inc. (Santa Clara, California) |
INVENTOR(S) | Glenn Hugh McGall (Palo Alto, California); Anthony D. Barone (Palo Alto, California) |
ABSTRACT | Nucleic acid labeling compounds including the following are disclosed: These compounds are useful for attaching a detectable label to a nucleic acid. |
FILED | Tuesday, September 28, 2010 |
APPL NO | 12/892531 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077311 | Byrne et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Robert H. Byrne (St. Petersburg, Florida); Eric Kaltenbacher (St. Petersburg, Florida); Xuewu Liu (Largo, Florida) |
ABSTRACT | Provided is a flow-through CO2 system for simultaneously measuring surface seawater pH, carbon dioxide fugacity (fCO2), and total dissolved inorganic carbon (DIC). All measurements are based on spectrophotometric determinations of solution pH at multiple wavelengths using sulfonephthalein indicators. |
FILED | Thursday, April 24, 2008 |
APPL NO | 12/108953 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/319 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077708 | Maestas et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Techguard Security, LLC (O'Fallon, Missouri) |
INVENTOR(S) | David Edward Maestas (Lake Saint Louis, Missouri); Brian Louis Cooper (St. Louis, Missouri) |
ABSTRACT | A method for determining a flow of data is described. The method includes determining whether a packet including a first number of at least one bit within a first set is assigned a classification value based on the at least one bit within the first set and determining a result to be applied to the packet upon determining that the packet is assigned the classification value. The method further includes analyzing, by a processor, at least one bit of a second number within a second set of the packet upon determining that the packet cannot be assigned the classification value based on the first number of at least one bit of the packet. |
FILED | Wednesday, November 01, 2006 |
APPL NO | 11/591802 |
ART UNIT | 2477 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/389 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077950 | Tsougarakis et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | ConforMIS, Inc. (Burlington, Massachusetts) |
INVENTOR(S) | Konstantinos Tsougarakis (Sunnyvale, California); Daniel Steines (Lexington, Massachusetts); Bhaskar Rao Vissa (San Jose, California); Philipp Lang (Lexington, Massachusetts); Barry J. Linder (Danville, California) |
ABSTRACT | The present invention relates to methods for determining meniscal size and shape for use in designing therapies for the treatment of various joint diseases. The invention uses an image of a joint that is processed for analysis. Analysis can include, for example, generating a thickness map, a cartilage curve, or a point cloud. This information is used to determine the extent of the cartilage defect or damage and to design an appropriate therapy, including, for example, an implant. Adjustments to the designed therapy are made to account for the materials used. |
FILED | Tuesday, August 10, 2010 |
APPL NO | 12/853599 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 08075904 | Sakamoto et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Regents of University of California (Oakland, California); Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Jeff S. Sakamoto (East Lansing, Michigan); Mark Henry Tuszynski (La Jolla, California); Thomas Gros (Fairfield, California); Christina Chan (Okemos, Michigan); Sumit Mehrotra (East Lansing, Michigan) |
ABSTRACT | Millimeter to nano-scale structures manufactured using a multi-component polymer fiber matrix are disclosed. The use of dissimilar polymers allows the selective dissolution of the polymers at various stages of the manufacturing process. In one application, biocompatible matrixes may be formed with long pore length and small pore size. The manufacturing process begins with a first polymer fiber arranged in a matrix formed by a second polymer fiber. End caps may be attached to provide structural support and the polymer fiber matrix selectively dissolved away leaving only the long polymer fibers. These may be exposed to another product, such as a biocompatible gel to form a biocompatible matrix. The polymer fibers may then be selectively dissolved leaving only a biocompatible gel scaffold with the pores formed by the dissolved polymer fibers. The scaffolds may be used in, among other applications, the repair of central and peripheral nerves. Scaffolds for the repair of peripheral nerves may include a reservoir for the sustained release of nerve growth factor. The scaffolds may also include a multifunctional polyelectrolyte layer for the sustained release of nerve growth factor and enhance biocompatibility. |
FILED | Tuesday, September 02, 2008 |
APPL NO | 12/203068 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/422 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076136 | Clarke et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the United States National Aeronautics and Space Administration (Washington, District of Columbia); University of Houston (Houston, Texas); Universities Space Research Association (Columbia, Maryland) |
INVENTOR(S) | Mark S. F. Clarke (Houston, Texas); Alamelu Sundaresan (Sugarland, Texas); Neal R. Pellis (Pearland, Texas) |
ABSTRACT | The present disclosure provides ex vivo-derived mineralized three-dimensional bone constructs. The bone constructs are obtained by culturing osteoblasts and osteoclast precursors under randomized gravity vector conditions. Preferably, the randomized gravity vector conditions are obtained using a low shear stress rotating bioreactor, such as a High Aspect Ratio Vessel (HARV) culture system. The bone constructs of the disclosure have utility in physiological studies of bone formation and bone function, in drug discovery, and in orthopedics. |
FILED | Thursday, March 29, 2007 |
APPL NO | 11/693662 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076283 | Marchionni et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Acorda Therapeutics, Inc. (Hawthorne, New York); Beth Israel Deaconesss Medical Center (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Mark Marchionni (Arlington, Massachusetts); Ralph Kelly (Chestnut Hill, Massachusetts); Beverly Lorell (Needham, Massachusetts); Douglas B. Sawyer (Brookline, Massachusetts) |
ABSTRACT | The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene. |
FILED | Tuesday, December 29, 2009 |
APPL NO | 12/655361 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077103 | Acosta et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Roberto J. Acosta (North Olmsted, Ohio); Carol Kory (Westlake, Ohio); Kevin M. Lambert (North Royalton, Ohio) |
ABSTRACT | A cup waveguide antenna with integrated polarizer and OMT for simultaneously communicating left and right hand circularly polarized electromagnetic waves is adjustable to obtain efficient propagation and reception of electromagnetic waves. The antenna includes a circular waveguide having an orthomode transducer utilizing first and second pins longitudinally spaced apart and oriented orthogonally with respect to each other. Six radially-oriented adjustable polarizer screws extend from the exterior to the interior of the waveguide. A septum intermediate the first and second pins is aligned with the first pin. Adjustment of the polarizer screws enables maximized propagation of and/or response to left hand circularly polarized electromagnetic waves by the first pin while simultaneously enabling maximized propagation of and/or response to right hand circularly polarized electromagnetic waves by the second pin. |
FILED | Saturday, July 07, 2007 |
APPL NO | 11/774574 |
ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Communications: Radio wave antennas 343/756 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078004 | Kang et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
INVENTOR(S) | Yong Q. Kang (Elkton, Maryland); Young-Heon Jo (Camden, Delaware); Xiao-Hai Yan (Newark, Delaware) |
ABSTRACT | A method for registering a first image to a second image using a similarity transformation. The each image includes a plurality of pixels. The first image pixels are mapped to a set of first image coordinates and the second image pixels are mapped to a set of second image coordinates. The first image coordinates of two reference points in the first image are determined. The second image coordinates of these reference points in the second image are determined. A Cartesian translation of the set of second image coordinates is performed such that the second image coordinates of the first reference point match its first image coordinates. A similarity transformation of the translated set of second image coordinates is performed. This transformation scales and rotates the second image coordinates about the first reference point such that the second image coordinates of the second reference point match its first image coordinates. |
FILED | Monday, November 05, 2007 |
APPL NO | 11/935012 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Image analysis 382/276 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078309 | Eyre et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Francis B. Eyre (Los Angeles, California); Wolfgang Fink (Montrose, California) |
ABSTRACT | Disclosed herein is a method of making a three dimensional mold comprising the steps of providing a mold substrate; exposing the substrate with an electromagnetic radiation source for a period of time sufficient to render the portion of the mold substrate susceptible to a developer to produce a modified mold substrate; and developing the modified mold with one or more developing reagents to remove the portion of the mold substrate rendered susceptible to the developer from the mold substrate, to produce the mold having a desired mold shape, wherein the electromagnetic radiation source has a fixed position, and wherein during the exposing step, the mold substrate is manipulated according to a manipulation algorithm in one or more dimensions relative to the electromagnetic radiation source; and wherein the manipulation algorithm is determined using stochastic optimization computations. |
FILED | Tuesday, March 31, 2009 |
APPL NO | 12/415206 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Generic control systems or specific applications 7/198 |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 08078313 | McDonald et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Glenn Edward McDonald (Alexandria, Virginia); Wilson Wong (Bowie, Maryland) |
ABSTRACT | Systems and methods for sorting a plurality of unaddressed items may comprise receiving delivery point address data. Furthermore, systems and methods for sorting a plurality of unaddressed items may comprise sorting the plurality of unaddressed items based on the delivery point address data. The plurality of unaddressed items may be sorted in an order in which they are to be delivered within a delivery zone specified by the delivery point address data. |
FILED | Thursday, September 30, 2004 |
APPL NO | 10/952818 |
ART UNIT | 3651 — Material and Article Handling |
CURRENT CPC | Data processing: Generic control systems or specific applications 7/223 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078314 | Barnum et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Timothy B. Barnum (Severna Park, Maryland); George Laws (Goldvein, Virginia); Leung M. Shiu (Gaithersburg, Maryland); James E. Goodbar, III (Springfield, Virginia) |
ABSTRACT | Systems and methods that allow for orienting and delivering mail between a postage verifier and a mail sorter. A postage verifier includes an optical character reader for decoding addresses on mail pieces that do not have bar codes. A reverter orients mail from the postage verifier into a position required for processing by the mail sorter. A combination of mail carrying modules carry the mail from the reverter to the mail sorter. The mail sorter prints bar code information on mail lacking bar codes, when the data is available, and sorts the mail based on the bar code information. |
FILED | Thursday, January 17, 2008 |
APPL NO | 12/015926 |
ART UNIT | 3653 — Material and Article Handling |
CURRENT CPC | Data processing: Generic control systems or specific applications 7/224 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08078549 | Willoughby et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Stuart Willoughby (Oakton, Virginia); Ronald F. Smith (Rockville, Maryland); Daniel Lord (Upper Marlboro, Maryland); Charles Outman (Damascus, Maryland); Joseph A. Otten (San Francisco, California); John Gullo (Alexandria, Virginia); Anna Vale (Pearland, Texas) |
ABSTRACT | A label and a method for providing a label to a user is described. The label may be a mailing label to be placed on letters or parcels. The label includes information such as postage, delivery address, return address, and a barcode for tracking delivery information. A user may request both a label and postage in what, to the user, appears to be a single computerized connection on a single internet web-page. A postage indicia is provided through a postage provider with whom the user has a deposit or credit. The label itself may be generated through a label-generating application hosted or generated by an entity separate from the postage provider. |
FILED | Wednesday, May 15, 2002 |
APPL NO | 10/144870 |
ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/404 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 08076141 | Jackson et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | E.I. du Pont de Nemours and Company (Wilmington, Delaware); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
INVENTOR(S) | David Peter Jackson (New York, New York); Namiko Satoh Nagasawa (Huntington, New York); Hajime Sakai (Newark, Delaware); Nobuhiro Nagasawa (Akita, Japan) |
ABSTRACT | The invention relates to the isolation and characterization of a maize gene, RAMOSA3 (RA3), responsible for meristem development and inflorescence development including branching. The gene, gene product, and regulatory regions may be used to manipulate branching, meristem growth, inflorescence development and arrangement, and ultimately to improve yield of plants. The invention includes the gene and protein product as well as the use of the same for temporal and spatial expression in transgenic plants to alter plant morphology and affect yield in plants. The invention also includes the gene and protein product for SISTER OF RAMOSA3 (SRA). |
FILED | Tuesday, March 08, 2011 |
APPL NO | 13/042531 |
ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/468 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 08076504 | Kubatova et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The University of North Dakota (Grand Forks, North Dakota) |
INVENTOR(S) | Alena Kubatova (Grand Forks, North Dakota); Wayne S. Seames (Grand Forks, North Dakota); Brian M. Tande (Fargo, North Dakota) |
ABSTRACT | A method for producing a mixture of short chain carboxylic acids from biomass includes adding biomass to a reactor vessel, heating the biomass to crack it, removing undesired and unreacted materials and light ends from the cracked biomass, and removing a mixture containing carboxylic acids having carbon chain lengths between C2 and C16. A composition includes a carboxyl group-containing compound derived by cracking biomass and having a carboxyl carbon chain length between C2 and C16. |
FILED | Wednesday, December 31, 2008 |
APPL NO | 12/319028 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 560/179 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 08077743 | Belding et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | QUALCOMM Incorporated (San Diego, California) |
INVENTOR(S) | Peter Belding (San Diego, California); James T. Determan (Encinitas, California); Ronald Bloom (San Diego, California) |
ABSTRACT | The disclosed embodiments provide methods and apparatus for offset interleaving of media frames for transmission over a communication network. In one aspect, a method for interleaving a stream of media frames for transmission over a communication network includes the acts of defining a plurality of packets and interleaving a stream of media frames among the packets. |
FILED | Wednesday, November 17, 2004 |
APPL NO | 10/991618 |
ART UNIT | 2471 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/476 |
VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
US 08074419 | Humphress et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | David L. Humphress (Campbellsville, Kentucky); Steven N. Flinchum (Elkhorn, Kentucky) |
ABSTRACT | Non-masonry building block components, including a standard hollow-bodied block component with horizontal and vertical locking capabilities which removes the need for bonding material such as glue, mortar or other adhesives. Modified dovetails on the upper and lower surface of the building components prevent vertical movement while resistance locks on each end of the block prevent horizontal movement. Typically, use of the non-masonry building components would allow for constructing permanent or temporary structures having vertical and horizontal channels in which to allow plumbing or electrical conduit. The incorporation of materials, such as sand or similar substance, would form a bullet-resistant barrier for use in military operations. Additionally, structures formed from the block components could easily be assembled or disassembled on site without the need for skilled labor, specialized tools, demolition and clean up. |
FILED | Monday, July 07, 2008 |
APPL NO | 12/168313 |
ART UNIT | 3635 — Static Structures, Supports and Furniture |
CURRENT CPC | Static structures 052/607 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 08074827 | Pettit et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Donald Roy Pettit (Houston, Texas); Mark Milton Weislogel (Tigard, Oregon); Paul Concus (Kensington, California); Robert Finn (Palo Alto, California) |
ABSTRACT | A beverage cup comprised by an open top and at least one channel defined by a corner with an acute angle so placed that the channel runs along the cup side from the cup bottom to the cup rim. In the absence of significant gravitational force as found in microgravity, weightless or weightlessness of spacecraft or the International Space Station, capillary forces between the beverage and the cup wall allow the beverage to creep along the channel and be in near proximity to the open cup rim. Lips placed at or near the channel at the rim can readily sip, drink, and consume the beverage without the need for a straw and without undue spillage for normal drinking motions including toasting. The channel conducts the beverage via capillary forces from the bottom of the cup to the rim until the beverage has been consumed. |
FILED | Thursday, November 05, 2009 |
APPL NO | 12/612698 |
ART UNIT | 3788 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Receptacles 220/710.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08075921 | Fowler et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Deparment of Health and Human Services (Washington, District of Columbia); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Daniel H. Fowler (Bethesda, Maryland); Unsu Jung (Ashburn, Virginia); Ronald E. Gress (Gaithersburg, Maryland); Bruce Levine (Cherry Hill, New Jersey); Carl June (Merion Station, Pennsylvania) |
ABSTRACT | Methods for generating highly enriched Th1/Tc1 and Th2/Tc2 functions are described. In particular, the generation of these functions are attained by the addition of an immune suppression drug, rapamycin or a rapamycin derivative compound. In addition to enhanced purity of T cell function, the T cells generated in rapamycin also express molecules that improve immune T cell function such as CD28 and CD62L. Such rapamycin generated functional T cell subsets may have application in the prevention or treatment of GVHD after allogeneic hematopoietic stem cell transplantation, the treatment of autoimmunity, or the therapy of infection or cancer. |
FILED | Tuesday, March 30, 2010 |
APPL NO | 12/750374 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/577 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08076372 | Inman et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | Government of the United States (Rockville, Maryland) |
INVENTOR(S) | John K. Inman (Bethesda, Maryland); Atul Goel (Lucknow, India); Ettore Appella (Chevy Chase, Maryland); Jim A. Turpin (Frederick, Maryland); Marco Schito (Rockville, Maryland) |
ABSTRACT | Certain thiol and acylthiol compounds inhibit retrovirus growth by attacking the highly conserved zinc finger regions of essential viral proteins. These compounds, compositions containing them, and methods of using them to treat retroviral infections such as HIV are described. These compounds are also useful for preparation of vaccines comprised of inactivated retroviruses such as HIV, prevention of the transmission of such retroviruses, and detection of retroviral proteins. |
FILED | Monday, March 30, 2009 |
APPL NO | 12/414321 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/513 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08077177 | Moore et al. |
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FUNDED BY |
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APPLICANT(S) | |
ASSIGNEE(S) | |
INVENTOR(S) | Jason A. Moore (Taberg, New York); Aaron W. McVay (Ava, New York) |
ABSTRACT | Method, computer executable program and apparatus for displaying massive amounts of potentially non-uniform gridded data through the use of view dependant refinement. An initial minimal representation is created. A view dependant refinement criterion is then used to ascertain the perceived quality. If necessary, refinements and decimations to the current representation are performed. The representation is then provided to graphics hardware for display. |
FILED | Wednesday, December 12, 2007 |
APPL NO | 12/002854 |
ART UNIT | 2628 — Selective Visual Display Systems |
CURRENT CPC | Computer graphics processing and selective visual display systems 345/428 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 13, 2011.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2011/fedinvent-patents-20111213.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page