FedInvent™ Patents

Patent Details for Tuesday, May 29, 2012

This page was updated on Monday, March 27, 2023 at 03:21 AM GMT

Department of Defense (DOD)

08186090 — Adjustable buttstock assembly

US 08186090	Chiarolanza et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Joseph P. Chiarolanza (Oak Ridge, New Jersey); Kevin T. Bauer (Lakeville, Pennsylvania); Marcos A. Collado (Landing, New Jersey)
ABSTRACT	An adjustable buttstock assembly for a hand carried weapons, wherein an inner stock extends from and slidably moves into an outer stock to provide the length adjustment and where a set of opposed spring loaded engagement pins, located in the end of the inner stock, extend through a set of discrete, opposed openings in the outer stock to securely hold the stocks in position one relative to the other. One of the engagement pins, engages into one of a series of discrete holes located in the lower side of the outer stock, while the other engages into one of a series of partial oval opening, opposed thereto, the series of partial oval openings located on the upper side of the outer stock separated by flat teeth, to form a rack, with each partial oval opening into an open channel running the length of the rack. Such that when the lower engagement pin is compressed into the lower opening in which it may be and the upper engagement pin then rotated out of the partial oval opening into the channel—the inner and outer stocks are then free to move one with respect to the other to extend or compress the adjustable buttstock. Further, the inner stock is fixed to a backplate that engages with the receiver of the weapon, and provides protection for a hydraulic buffer that engages with the receiver of the weapon and extends into the inner stock.
FILED	Monday, June 28, 2010
APPL NO	12/824570
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Firearms 042/73
VIEW PATENT	@ USPTO: Full Text PDF

08186164 — Turbine engine fuel injector

US 08186164	Cowan
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	Curtis C. Cowan (East Hampton, Connecticut)
ABSTRACT	A gas turbine engine is piloted with a pilot flow of fuel delivered to a combustor as a liquid. A first additional flow of the fuel is also delivered to the combustor as a liquid. A second additional flow of the fuel is vaporized and delivered to the combustor as a vapor. A fuel injector may have passageways associated with each of the three flows.
FILED	Tuesday, August 30, 2011
APPL NO	13/220757
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/742
VIEW PATENT	@ USPTO: Full Text PDF

08186168 — Thrust balance of rotor using fuel

US 08186168	Heathco
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S)	Craig Heathco (Martinsville, Indiana)
ABSTRACT	A method of at least partially balancing axial thrust loads and an engine in which the method is carried out is disclosed herein. The engine includes a combustion chamber and a fuel system operable to direct pressurized fuel to the combustion chamber. The engine also includes a rotor operable to rotate about a centerline axis and subjected to axial thrust loads during operation. The engine also includes a balance piston engaged with the rotor. The balance piston includes a pressure face positioned in a thrust cavity. The engine also includes a fluid passageway extending between the fuel system and the thrust cavity. Pressurized fuel is delivered to the pressure face to counteract axial thrust loads on the rotor.
FILED	Friday, July 18, 2008
APPL NO	12/175705
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/772
VIEW PATENT	@ USPTO: Full Text PDF

08186232 — Displacement sensor

US 08186232	McDearmon et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S)	The Timken Company (Canton, Ohio)
INVENTOR(S)	Graham McDearmon (North Canton, Ohio); Brent Mathie (Louisville, Ohio)
ABSTRACT	A displacement, strain, and/or force sensor assembly (10, 110) has a mounting structure (12) with an anisotropic stiffness to facilitate the measurement of displacements, strains, and/or forces along the X-axis, while minimizing errors due to undesired displacements, strains, and/or forces along the Y- and Z-axes, and rotations about the X-, Y-, and Z-axes. A pedestal (30, 130) configured to respond to axial displacements along the X-axis is centrally disposed on the X-axis of the mounting structure (12), and a displacement or strain sensor (38) is coupled to the pedestal (30) to provide a measure of the displacements, strains, and/or forces. Contact pads (14, 114) are formed on opposite ends of the X-axis of the mounting structure, to enable the displacement and/or strain sensor assembly to be secured to an application structure.
FILED	Tuesday, May 29, 2007
APPL NO	12/298992
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/862.632
VIEW PATENT	@ USPTO: Full Text PDF

08186275 — Non-lethal projectile for dispersing payload upon target impact

US 08186275	Woodall et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert Woodall (Panama City, Florida); Felipe Garcia (Panama City, Florida); Greg Reitmeyer (Panama City, Florida)
ABSTRACT	A non-lethal projectile has an enclosed frangible shell with a nose assembly coupled thereto. The nose assembly is designed to be frangible and absorb shock energy incident on the nose assembly. Frangible containers disposed in the shell occupy a portion of the volume defined thereby such that spaces between the containers are defined. Each container is configured to divide into particles when the container fractures. Each container contains at least one payload material. A gelatinous carbomer fills the spaces between the containers.
FILED	Monday, May 17, 2010
APPL NO	12/800819
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ammunition and explosives 12/502
VIEW PATENT	@ USPTO: Full Text PDF

08187032 — Guided missile/launcher test set reprogramming interface assembly J2 connector clamp

US 08187032	Park et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Bruce J. Park (Camarillo, California); Michael A. Torres (Newbury Park, California); Mark A. Doty (Port Hueneme, California)
ABSTRACT	A guided missile/launcher test set reprogramming interface assembly J2 connector clamp includes a frame having an upper side, a lower side, and at least one aperture with a threaded portion that extends through the frame and is adapted to threadingly associate with threads on a connector. Rotational torque is transferred away from the frame and connector when a securing mechanism is actuated.
FILED	Tuesday, January 31, 2012
APPL NO	13/363250
ART UNIT	2839 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Electrical connectors 439/574
VIEW PATENT	@ USPTO: Full Text PDF

08187257 — Optical devices and methods for selective and conventional photocoagulation of the retinal pigment epithelium

US 08187257	Lin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Charles P. Lin (Arlington, Massachusetts); Clemens Alt (Cambridge, Massachusetts)
ABSTRACT	The present invention provides devices and methods for applying radiation to the retina of a patient. In one embodiment, an apparatus includes a radiation source for generating a radiation beam suitable for absorption by retinal pigment epithelial cells. One or more optical components are included to direct the beam onto the retina. A scanner is optically coupled to the radiation source to control movement of the beam in two dimensions to allow a scan over the retina. A controller applies control signals to the scanner to adjust beam movement to illuminate a plurality of retinal locations in a temporal sequence according to a predefined pattern. The device can be operated in one mode to effect selective targeting of retinal pigment epithelial cells, or in another mode to effect thermal photocoagulation of the retina.
FILED	Monday, October 31, 2005
APPL NO	11/263677
ART UNIT	3769 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery 66/10
VIEW PATENT	@ USPTO: Full Text PDF

08187489 — Biodegradable ionic liquids for aircraft deicing

US 08187489	Davis
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Matthew C. Davis (Ridgecrest, California)
ABSTRACT	A process and deicing composition.
FILED	Wednesday, March 23, 2011
APPL NO	13/069671
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Compositions 252/70
VIEW PATENT	@ USPTO: Full Text PDF

08187611 — Anti-peptide antibodies that cross react with protective antigen of Bacillus anthracis and uses thereof

US 08187611	Abboud et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)	Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S)	Nareen Abboud (New Rochelle, New York); Arturo Casadevall (New Rochelle, New York)
ABSTRACT	The present invention provides a purified peptide comprising at least one of the sequences LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a vaccine, a method to protect or treat an animal from anthrax toxin, a method of making a vaccine and the use of the peptide. The present invention also provides a monoclonal antibody that specifically binds to a peptide sequence comprising at least one of the following peptide sequences: LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a method to protect or treat an animal from anthrax toxin, a method of making a vaccine, a pharmaceutical composition, a method of making a pharmaceutical composition, and the use of the monoclonal antibody.
FILED	Tuesday, October 05, 2010
APPL NO	12/924813
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/246.100
VIEW PATENT	@ USPTO: Full Text PDF

08187673 — Methods utilizing scanning probe microscope tips and products thereof or produced thereby

US 08187673	Mirkin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Chad A. Mirkin (Wilmette, Illinois); Richard Piner (Des Plaines, Illinois); Seunghun Hong (Chicago, Illinois)
ABSTRACT	The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). DPN utilizes a scanning probe microscope (SPM) tip (e.g., an atomic force microscope (AFM) tip) as a “pen,” a solid-state substrate (e.g., gold) as “paper,” and molecules with a chemical affinity for the solid-state substrate as “ink.” Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecules in submicrometer dimensions, making DPN useful in the fabrication of a variety of microscale and nanoscale devices. The invention also provides substrates patterned by DPN, including submicrometer combinatorial arrays, and kits, devices and software for performing DPN. The invention further provides a method of performing AFM imaging in air. The method comprises coating an AFM tip with a hydrophobic compound, the hydrophobic compound being selected so that AFM imaging performed using the coated AFM tip is improved compared to AFM imaging performed using an uncoated AFM tip. Finally, the invention provides AFM tips coated with the hydrophobic compounds.
FILED	Wednesday, October 31, 2007
APPL NO	11/933251
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/256
VIEW PATENT	@ USPTO: Full Text PDF

08187703 — Fiber-reinforced polymer composites containing functionalized carbon nanotubes

US 08187703	Zhu et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	William Marsh Rice University (Houston, Texas)
INVENTOR(S)	Jiang Zhu (Missouri City, Texas); Valery N. Khabashesku (Houston, Texas); Haiqing Peng (Houston, Texas); Enrique V. Barrera (Houston, Texas); John L. Margrave (Bellaire, Texas); Mary Lou Margrave, legal representative (Bellaire, Texas)
ABSTRACT	The present invention is directed to methods of integrating carbon nanotubes into epoxy polymer composites via chemical functionalization of carbon nanotubes, and to the carbon nanotube-epoxy polymer composites produced by such methods. Integration is enhanced through improved dispersion and/or covalent bonding with the epoxy matrix during the curing process. In general, such methods involve the attachment of chemical moieties (i.e., functional groups) to the sidewall and/or end-cap of carbon nanotubes such that the chemical moieties react with either the epoxy precursor(s) or the curing agent(s) (or both) during the curing process. Additionally, in some embodiments, these or additional chemical moieties can function to facilitate dispersion of the carbon nanotubes by decreasing the van der Waals attractive forces between the nanotubes.
FILED	Thursday, September 03, 2009
APPL NO	12/553721
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Stock material or miscellaneous articles 428/297.400
VIEW PATENT	@ USPTO: Full Text PDF

08187801 — Methods and kits to detect and monitor ovarian cancer and preeclampsia

US 08187801	Patankar et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Manish S. Patankar (Fitchburg, Wisconsin); Joseph P. Connor (Madison, Wisconsin); Jennifer A. Belisle (De Forest, Wisconsin)
ABSTRACT	The present invention provides methods and kits related to a prognostic, and, in certain embodiments, diagnostic indicator for ovarian cancer which comprises measuring the level of MUC16 bound to immune cells. The level of MUC16 bound to immune cells can by itself be an indicator of disease regression or recurrence, or this indicator can be used in conjunction with assays for serum CA125 and other diagnostic markers. The invention further provides methods and kits related to the detection of ovarian cancer by measuring levels of Siglec-9 expression on immune cells. As well, related methodologies are provided for the detection of preeclampsia in pregnant human subjects.
FILED	Friday, April 24, 2009
APPL NO	12/429573
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

08187802 — Cell lines useful for assessing modulation of autophagy

US 08187802	White et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Eileen White (Princeton, New Jersey); Anne Marie Strohecker (New York, New York); Robin Mathew (Monroe, New Jersey); Cristina Karp (North Brunswick, New Jersey)
ABSTRACT	Methods for screening for modulators of autophagy are disclosed. Methods for identifying genes whose expression inhibits autophagy, as well as genes whose expression promotes autophagy, are disclosed. Also disclosed are methods for identifying compounds that stimulate autophagy, as well as compounds that inhibit autophagy. Cell lines that may be used in the methods of identification are also disclosed.
FILED	Thursday, November 19, 2009
APPL NO	12/622410
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

08187814 — Methods for concurrent identification and quantification of an unknown bioagent

US 08187814	Ecker et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Ibis Biosciences, Inc. (Carlsbad, California)
INVENTOR(S)	David J. Ecker (Encinitas, California); Rangarajan Sampath (San Diego, California); Lawrence B. Blyn (Mission Viejo, California); Steven A. Hofstadler (Vista, California); Thomas A. Hall (Oceanside, California)
ABSTRACT	The present invention provides methods for the quantification of an unknown bioagent in a sample by amplification of nucleic acid of the bioagent, and concurrent amplification of a known quantity of a calibration polynucleotide from which are obtained a bioagent identifying amplicon and a calibration amplicon. Upon molecular mass analysis, mass and abundance data are obtained. The identity of the bioagent is then determined from the molecular mass of the bioagent identifying amplicon and the quantity of the identified bioagent in the sample is determined from the abundance data of the bioagent identifying amplicon and the abundance data of the calibration amplicon.
FILED	Friday, January 08, 2010
APPL NO	12/684742
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.120
VIEW PATENT	@ USPTO: Full Text PDF

08187881 — Methods related to wound healing

US 08187881	Smith et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA)
APPLICANT(S)
ASSIGNEE(S)	Stemnion, Inc. (Pittsburgh, Pennsylvania)
INVENTOR(S)	Charlotte A. Smith (Pittsburgh, Pennsylvania); Catherine J. Trumpower (Pittsburgh, Pennsylvania); Vivienne S. Marshall (Glenshaw, Pennsylvania)
ABSTRACT	The invention is directed to methods for the treatment of wounds. Such methods utilize novel compositions, including but not limited to amnion-derived multipotent cells (herein referred to as AMP cells), conditioned media derived therefrom (herein referred to as amnion-derived cellular cytokine suspension or ACCS), cell lysates derived therefrom, cell products derived therefrom, each alone or in combination.
FILED	Tuesday, December 01, 2009
APPL NO	12/592658
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/405
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08187907 — Solder structures for fabrication of inverted metamorphic multijunction solar cells

US 08187907	Newman
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Space Vehicles Directorate Contracting Division (AFRL/RVK)
APPLICANT(S)
ASSIGNEE(S)	Emcore Solar Power, Inc. (Albuquerque, New Mexico)
INVENTOR(S)	Fred Newman (Albuquerque, New Mexico)
ABSTRACT	A method of manufacturing a solar cell by providing a first substrate; depositing on the first substrate a sequence of layers of semiconductor material forming a solar cell including a top subcell and a bottom subcell; forming a metal back contact over the bottom subcell; forming a group of discrete, spaced-apart first bonding elements over the surface of the back metal contact; attaching a surrogate substrate on top of the back metal contact using the bonding elements; and removing the first substrate to expose the surface of the top subcell.
FILED	Friday, May 07, 2010
APPL NO	12/775946
ART UNIT	2812 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/66
VIEW PATENT	@ USPTO: Full Text PDF

08187923 — Laser release process for very thin Si-carrier build

US 08187923	Andry et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Paul Stephen Andry (Yorktown Heights, New York); Leena Paivikki Buchwalter (Hopewell Junction, New York); Matthew J. Farinelli (Riverdale, New York); Sherif A. Goma (White Plains, New York); Raymond R. Horton (Dover Plains, New York); Edmund J. Sprogis (Underhill, Vermont)
ABSTRACT	A laser release and glass chip removal process for a integrated circuit module avoiding carrier edge cracking is provided.
FILED	Thursday, July 03, 2008
APPL NO	12/167745
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/118
VIEW PATENT	@ USPTO: Full Text PDF

08188051 — Metadherin polypeptides, encoding nucleic acids and methods of use

US 08188051	Ruoslahti et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	The Burnham Institute (La Jolla, California)
INVENTOR(S)	Erkki Ruoslahti (Rancho Santa Fe, California); Darren M. Brown (Carlsbad, California)
ABSTRACT	Metadherin, a protein that controls metastasis, and variants of metadherin are described. DNA sequences encoding the same and methods of production are described. Therapies involving the application of metadherin, binding agents that bind to metadherin, such as antibodies, and expression modulating agents, such as siRNA, are described. The use of metadherin or metadherin variants for delivering desired substances to particular lung tissue is described. A method of diagnosing metastatic cells based on the presence of metadherin is described.
FILED	Tuesday, December 16, 2008
APPL NO	12/336409
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/19.400
VIEW PATENT	@ USPTO: Full Text PDF

08188116 — Agents for therapy efficacy monitoring and deep tissue imaging

US 08188116	Bornhop et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Darryl J. Bornhop (Nashville, Tennessee); H. Charles Manning (Nashville, Tennessee); Mingfeng Bai (St. Louis, Missouri); Shelby K. Wyatt (Nashville, Tennessee)
ABSTRACT	Compounds and methods related to NIR molecular imaging, in-vitro and in-vivo functional imaging, therapy/efficacy monitoring, and cancer and metastatic activity imaging. Compounds and methods demonstrated pertain to the field of peripheral benzodiazepine receptor imaging, metabolic imaging, cellular respiration imaging, cellular proliferation imaging as targeted agents that incorporate signaling agents.
FILED	Friday, July 13, 2007
APPL NO	11/777752
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/307
VIEW PATENT	@ USPTO: Full Text PDF

08188141 — Isomigrastatin analogs in the treatment of cancer

US 08188141	Danishefsky et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S)	Samuel J. Danishefsky (Englewood, New Jersey); Mihirbaran Mandal (New York, New York); David C. Dorn (New York, New York); Malcolm A. S. Moore (New York, New York)
ABSTRACT	The present invention provides compounds having formula (I): (I) wherein n, R₁-R₅, R_a-R_b, Q, Y₁and Y₂are as defined herein; and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders involving increased angiogenesis.
FILED	Friday, September 23, 2005
APPL NO	11/663580
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/431
VIEW PATENT	@ USPTO: Full Text PDF

08188142 — Polymers from propenyl ether monomers

US 08188142	Purdy
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Andrew P Purdy (Alexandria, Virginia)
ABSTRACT	The compounds shown below. R is —O—, —O—(CH₂)_n—O—, or —(O—CH₂—CH₂)_n—O—; and n is a positive integer. Heating an allyl ether compound in the presence of Fe(CO)₅and a base to form the below propenyl ether monomer. Polymerizing the below propenyl ether monomer.
FILED	Wednesday, July 16, 2008
APPL NO	12/174232
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/445
VIEW PATENT	@ USPTO: Full Text PDF

08188220 — Methods and compositions related to targeting wounds, regenerating tissue, and tumors

US 08188220	Ruoslahti et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S)	Erkki Ruoslahti (LaJolla, California); Tero Jarvinen (LaJolla, California)
ABSTRACT	Disclosed are compositions and methods useful for targeting regenerating tissue, wounds, and tumors. The compositions and methods are based on peptide sequences that selectively bind to and home to regenerating tissue, wound sites, and tumors in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to regenerating tissue, wound sites, and tumors in animals.
FILED	Thursday, December 06, 2007
APPL NO	11/951819
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/328
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08188257 — Direct quantification of ribosome inactivating protein

US 08188257	Dorsey
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Russell M. Dorsey (Fallston, Maryland)
ABSTRACT	A method for detecting ribosome inactivating protein (RIP) activity in a sample is provided that involves contacting a sample that contains an RIP with an inventive substrate that is depurinated to form product. The product is hybridized to a template and cleaved by an apurinic/apyrimidinic endonuclease such that releasing the blocked 3′ end only in a sample that contains RIP activity. The 5′ end of the product serves as a primer for extension by a polymerase reaction. The newly synthesized strand complementary to the template is detected by RT-PCR processes. A kit is provided suitable for field or laboratory use.
FILED	Monday, June 28, 2010
APPL NO	12/824323
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/24.330
VIEW PATENT	@ USPTO: Full Text PDF

08188422 — Fabrication of three-dimensional ion optics assemblies by metallization of non-conductive substrates

US 08188422	Amerom et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Space and Missile Defense Command (SMDC) U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Friso van Amerom (St. Petersburg, Florida); Ashish Chaudhary (St. Petersburg, Florida); Shekhar Bhansali (Tampa, Florida); Robert T. Short (St. Petersburg, Florida); George Steimle (St. Petersburg, Florida)
ABSTRACT	A die assembly for creating a ring electrode including a cylindrically-shaped die base, two die walls and a die top sized to fit inside a cylindrical die housing. The die base and die top having a series of concentric elevations used as impressions to form on two ends of the ring electrode. A method of fabricating an LTCC ring electrode using the die assembly is also provided.
FILED	Thursday, February 04, 2010
APPL NO	12/700355
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Radiant energy 250/281
VIEW PATENT	@ USPTO: Full Text PDF

08188456 — Thermionic electron emitters/collectors have a doped diamond layer with variable doping concentrations

US 08188456	Nemanich et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Robert J. Nemanich (Tempo, Arizona); Franz A. M. Koeck (Tempe, Arizona)
ABSTRACT	A thermionic electron emitter/collector includes a substrate and a doped diamond electron emitter/collector layer on the substrate. The doped diamond electron emitter/collector layer has at least a first and a second doping concentration as a function of depth such that the first doping concentration is different from the second doping concentration.
FILED	Tuesday, February 12, 2008
APPL NO	12/029602
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/10
VIEW PATENT	@ USPTO: Full Text PDF

08188483 — Silicon carbide devices having smooth channels

US 08188483	Das et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)	Cree, Inc. (Durham, North Carolina)
INVENTOR(S)	Mrinal K. Das (Durham, North Carolina); Michael Laughner (Clayton, North Carolina)
ABSTRACT	Power devices are provided including a p-type conductivity well region and a buried p⁺ conductivity region in the p-type conductivity well region. An n⁺ conductivity region is provided on the buried p⁺ conductivity region. A channel region of the power device is provided adjacent the buried p⁺ conductivity region and n⁺ conductivity region, the channel region of the power device having a root mean square (RMS) surface roughness of less than about 1.0 Å.
FILED	Thursday, April 16, 2009
APPL NO	12/424960
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/77
VIEW PATENT	@ USPTO: Full Text PDF

08188513 — Nanowire and larger GaN based HEMTS

US 08188513	Hersee et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Stephen D. Hersee (Albuquerque, New Mexico); Xin Wang (Albuquerque, New Mexico)
ABSTRACT	Nanowire and larger, post-based HEMTs, arrays of such HEMTs, and methods for their manufacture are provided. In one embodiment, a HEMT can include a III-N based core-shell structure including a core member (e.g., GaN), a shell member (e.g., AlGaN) surrounding a length of the core member and a two-dimensional electron gas (2-DEG) at the interface therebetween. The core member including a nanowire and/or a post can be disposed over a doped buffer layer and a gate material can be disposed around a portion of the shell member. Exemplary methods for making the nanowire HEMTs and arrays of nanowire HEMTs can include epitaxially forming nanowire(s) and epitaxially forming a shell member from each formed nanowire. Exemplary methods for making the post HEMTs and arrays of post HEMTs can include etching a III-N layer to form III-N post(s) followed by formation of the shell member(s).
FILED	Monday, October 06, 2008
APPL NO	12/246044
ART UNIT	2813 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/194
VIEW PATENT	@ USPTO: Full Text PDF

08188581 — Mechanical coupling in a multi-chip module using magnetic components

US 08188581	Shi et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Oracle America, Inc. (Redwood Shores, California)
INVENTOR(S)	Jing Shi (Carlsbad, California); Hiren D. Thacker (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California); John E. Cunningham (San Diego, California)
ABSTRACT	A multi-chip module (MCM) is described. This MCM includes at least two substrates that are remateably mechanically coupled by positive and negative features on facing surfaces of the substrates. These positive and negative features mate with each other. In particular, a positive feature may mate with a given pair of negative features, which includes negative features on each of the substrates. Furthermore, at least one of the negative features in the given pair may include a hard magnetic material, and the positive feature and the other negative feature in the given pair may include a soft magnetic material that provide a flux-return path to the hard magnetic material. In this way, the hard magnetic material may facilitate the remateable mechanical coupling of the substrates.
FILED	Monday, September 28, 2009
APPL NO	12/568024
ART UNIT	2891 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/673
VIEW PATENT	@ USPTO: Full Text PDF

08188622 — Tunable resonant frequency kinetic energy harvester

US 08188622	Waters et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Richard Waters (San Diego, California); Mark Fralick (San Diego, California); Hugo Jazo (San Diego, California); Brad Chisum (San Diego, California)
ABSTRACT	An energy harvester comprising: a substrate; two magnets coupled to the substrate in close proximity to each other with like magnetic poles facing each other creating a flux gap; a coil coupled to the substrate and disposed within the flux gap, wherein the coil and the magnets are coupled to the substrate such that substrate acceleration causes relative elastic motion between the magnets and the coil thereby exposing the coil to a changing magnetic flux; and a resonant frequency tuner coupled to the substrate and configured to adjust the resonant frequency between the coil and the magnets.
FILED	Thursday, November 12, 2009
APPL NO	12/616904
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Electrical generator or motor structure 310/15
VIEW PATENT	@ USPTO: Full Text PDF

08188636 — Energy generator systems with a voltage-controlled switch

US 08188636	Baird et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Space and Missile Defense Command (SMDC)
APPLICANT(S)
ASSIGNEE(S)	Loki Incorporated (Rolla, Missouri)
INVENTOR(S)	Jason Baird (Rolla, Missouri); Sergey Shkuratov (Lubbock, Texas)
ABSTRACT	A first energy generating system comprises a ferromagnetic generator coupled to a voltage controlled switch. The ferromagnetic generator includes a ferromagnetic element generating a magnetic field and positioned within a pulse generating coil and near an explosive charge. Detonation of the explosive charge decreases the magnetic field and induces a pulse of electric energy in the pulse generating coil. When the magnitude of the electric energy reaches a certain level, the voltage controlled switch closes. A second energy generating system comprises a flux compression generator coupled to a voltage controlled switch. The flux compression generator includes a inductance coil generating a magnetic field within a metallic armature that includes an explosive charge. Detonation of the explosive charge changes the magnetic field and induces a pulse of electric energy in the inductance coil. When the magnitude of the electric energy reaches a certain level, the voltage controlled switch closes.
FILED	Friday, August 26, 2011
APPL NO	13/218954
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electrical generator or motor structure 310/319
VIEW PATENT	@ USPTO: Full Text PDF

08188638 — Cooling acoustic transducer with heat pipes

US 08188638	Ruffa
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Anthony A. Ruffa (Hope Valley, Rhode Island)
ABSTRACT	A transducer with a closed heat pipe is provided with a hot surface and a cold surface. The hot surface is in contact with the transducer interior and the cold surface is in contact with a cooler contact area. A fluid is used in the pipe which boils at the temperature of the hot surface and condenses at the temperature of the cold surface. A wick inside the heat pipe facilities the return by capillary action of the condensed fluid to the hot end. The heat pipe can be evacuated to adjust the boiling temperature of the fluid. A variant involves drilling additional holes into ceramic rings and inserting heat pipes. Increasing the heat pipe length into the tail mass and the piston increases the cool region for the fluid to condense; thereby improving the performance of the transducer.
FILED	Monday, July 27, 2009
APPL NO	12/462061
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electrical generator or motor structure 310/334
VIEW PATENT	@ USPTO: Full Text PDF

08188753 — Analog computation

US 08188753	Nestler et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Analog Devices, Inc. (Norwood, Massachusetts)
INVENTOR(S)	Eric Nestler (Harvard, Massachusetts); Vladimir Zlatkovic (Belmont, Massachusetts)
ABSTRACT	Some general aspects of the invention relate to a circuit and to a method for analog computation, for example, using switched capacitor integrated circuits. In some examples, a circuit includes a first group of capacitors and a second group of capacitors that may store charges during circuit operation. The first and/or the second group of capacitors may include multiple disjoint subsets of capacitors. An input circuit is provided for receiving a set of input signals and for inducing a charge on each of some or all capacitors in the first group of capacitors according to a corresponding input signal. Switches, for example, transistors controlled by a sequence of clock signals, are used to couple different sets of capacitors. Different configurations of the switches are used to form different sets of the capacitors among which charge can redistribute.
FILED	Friday, August 21, 2009
APPL NO	12/545590
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/658
VIEW PATENT	@ USPTO: Full Text PDF

08188761 — Soft error detection for latches

US 08188761	Fleischer et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Bruce M. Fleischer (Bedford Hills, New York); Michael K. Gschwind (Chappaqua, New York)
ABSTRACT	A system and method for soft error detection in digital ICs is disclosed. The system includes an observing circuit coupled to a latch, which circuit is capable of a response upon a state change of the latch. The system further includes synchronized clocking provided to the latch and to the observing circuit. For the latch, the clocking defines a window in time during which the latch is prevented from receiving data, and in a synchronized manner the clocking is enabling a response in the observing circuit. The clocking is synchronized in such a manner that the circuit is enabled for its response only inside the window when the latch is prevented from receiving data. The system may also have additional circuits that are respectively coupled to latches, with each the additional circuit and its respective latch receiving the synchronized clocking Responses of a plurality of circuits may be coupled in a configuration corresponding to a logical OR.
FILED	Monday, February 14, 2011
APPL NO	13/026472
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Electronic digital logic circuitry 326/9
VIEW PATENT	@ USPTO: Full Text PDF

08188862 — Remote detection of covertly carried metal objects

US 08188862	Tam et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Daniel Tam (San Diego, California); Jodi McGee (San Diego, California); Aldo Monges (San Diego, California)
ABSTRACT	An apparatus for remotely detecting metal objects carried by a person includes an antenna and a signal generator coupled to the antenna operable to cause the antenna to emit a first electromagnetic signal to the person at a frequency that is known to be resonant with the human body. The apparatus further includes a data capture device operable to capture response signal energy received by the antenna, the response signal energy being provided from the person in response to the first electromagnetic signal. Processing circuitry for the apparatus is operable to determine whether the response signal energy is indicative whether or not the person is carrying an appreciable amount of metal, based on reference response templates for persons that are known to be metal-free.
FILED	Monday, March 23, 2009
APPL NO	12/408768
ART UNIT	2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Communications: Electrical 340/561
VIEW PATENT	@ USPTO: Full Text PDF

08188890 — Systems and methods for enhancing obstacles and terrain profile awareness

US 08188890	He
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Aviation and Missile Life Cycle Management Command (AMCOM)
APPLICANT(S)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	Gang He (Morristown, New Jersey)
ABSTRACT	A display system for an aircraft includes a processing unit configured to receive data related to an aircraft profile and to supply display commands with symbology based on the aircraft profile; and a display device coupled the processing unit and configured to receive the display commands and operable to render a three-dimensional view with the symbology based on the aircraft profile. The symbology may include slope symbology.
FILED	Thursday, November 13, 2008
APPL NO	12/270439
ART UNIT	2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Communications: Electrical 340/963
VIEW PATENT	@ USPTO: Full Text PDF

08188901 — Superconductor analog to digital converter

US 08188901	Inamdar et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	Hypres, Inc. (Elmsford, New York)
INVENTOR(S)	Amol Inamdar (Elmsford, New York); Deepnarayan Gupta (Hawthorne, New York)
ABSTRACT	Superconductor analog-to-digital converters (ADC) offer high sensitivity and large dynamic range. One approach to increasing the dynamic range further is with a subranging architecture, whereby the output of a coarse ADC is converted back to analog and subtracted from the input signal, and the residue signal fed to a fine ADC for generation of additional significant bits. This also requires a high-gain broadband linear amplifier, which is not generally available within superconductor technology. In a preferred embodiment, a distributed digital fluxon amplifier is presented, which also integrates the functions of integration, filtering, and flux subtraction. A subranging ADC design provides two ADCs connected with the fluxon amplifier and subtractor circuitry that would provide a dynamic range extension by about 30-35 dB.
FILED	Monday, August 17, 2009
APPL NO	12/542585
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Coded data generation or conversion 341/156
VIEW PATENT	@ USPTO: Full Text PDF

08189191 — Spectroscopic imaging microscopy

US 08189191	Webb et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S)	Tufts University (Medford, Massachusetts)
INVENTOR(S)	Michael R. Webb (Somerville, Massachusetts); Christopher Lafratta (Revere, Massachusetts); David R. Walt (Boston, Massachusetts)
ABSTRACT	Disclosed herein are systems that include: (a) an objective lens system configured to collect light from a sample; (b) a first aperture positioned to allow a portion of the collected light received from the objective lens system to pass as input light; (c) a first lens positioned to transmit the input light received from the first aperture; (d) a dispersive element configured to spatially disperse the input light received from the first lens in a first plane; (e) a second lens positioned to transmit the spatially dispersed light; (f) a second aperture positioned to allow a portion of the spatially dispersed light received from the second lens to pass as detection light; and (g) a detector positioned to receive the detection light and configured to form at least one image of the sample.
FILED	Friday, September 26, 2008
APPL NO	12/239628
ART UNIT	2877 — Optics
CURRENT CPC	Optics: Measuring and testing 356/326
VIEW PATENT	@ USPTO: Full Text PDF

08189204 — Surface wave enabled darkfield aperture

US 08189204	Cui et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Xiquan Cui (Pasadena, California); Xin Heng (Somerville, Massachusetts); Changhuei Yang (Pasadena, California); Axel Scherer (Laguna Beach, California); Demetri Psaltis (Lausanne, Switzerland); Guoan Zheng (Pasadena, California)
ABSTRACT	Embodiments of the present invention relate to a surface wave enabled darkfield aperture structure comprising an aperture layer, a aperture in the aperture layer and a plurality of grooves around the aperture. The aperture layer has a first and second surface. The plurality of grooves is in the first surface. A surface wave propagates along at least the first surface. The plurality of grooves is configured to generate a darkfield at the aperture by modifying the surface wave to cancel out direct transmission of a uniform incident light field received by the aperture.
FILED	Wednesday, June 02, 2010
APPL NO	12/792059
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/521
VIEW PATENT	@ USPTO: Full Text PDF

08189257 — Optimized cascaded raman fiber-based laser source for high efficiency mid-infrared spectral generation

US 08189257	Rakich et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Institute for Soldier Nanotechnologies (ISN)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Peter T. Rakich (Albuquerque, New Mexico); Marin Soljacic (Belmont, Massachusetts); Yoel Fink (Brookline, Massachusetts)
ABSTRACT	A laser structure is provided that includes a pulsed source producing a pulsed signal having a low spontaneous noise component to its spectral output and a pulse-shape that is optimally flat. Also, the laser structure includes one or more optical fiber structures receiving the pulsed signal and performing Raman amplification. The pulsed signal is used to excite in the one or more optical fiber structures possessing normal chromatic dispersion, which acts as a nonlinear system for efficient mid-infrared spectral generation.
FILED	Friday, May 01, 2009
APPL NO	12/433980
ART UNIT	3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Optical: Systems and elements 359/337.500
VIEW PATENT	@ USPTO: Full Text PDF

08189306 — Dynamic grounding system and method

US 08189306	Jacobson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Boris Jacobson (Westford, Massachusetts); John Walker (Bolton, Massachusetts)
ABSTRACT	Dynamic grounding including monitoring the floating DC outputs of a power amplifier, detecting an imbalance in the floating DC outputs, generating a compensation signal in response to a detected imbalance, and adjusting the power amplifier to re-balance the floating DC outputs and suppress transients.
FILED	Friday, March 13, 2009
APPL NO	12/381557
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electricity: Electrical systems and devices 361/42
VIEW PATENT	@ USPTO: Full Text PDF

08189367 — Single event upset hardened static random access memory cell

US 08189367	Lawson et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	David C. Lawson (Haymarket, Virginia); Jason F. Ross (Fairfax, Virginia)
ABSTRACT	A single event upset (SEU) hardened memory cell to be utilized in static random access memories is disclosed. The SEU hardened memory cell includes a first transistor, a second transistor and a first resistor connected between a source of the first transistor and a drain of the second transistor. The SEU hardened memory cell also includes a third transistor, a fourth transistor and a second resistor connected between a source of the third transistor and a drain of the fourth transistor. The first resistor is also connected between a gate of the third transistor and the drain of the second transistor. The second resistor is also connected between a gate of the first transistor and the drain of the fourth transistor.
FILED	Friday, February 08, 2008
APPL NO	12/028042
ART UNIT	2827 — Semiconductors/Memory
CURRENT CPC	Static information storage and retrieval 365/154
VIEW PATENT	@ USPTO: Full Text PDF

08189428 — Methods and systems to detect changes in multiple-frequency band sonar data

US 08189428	Orlin et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Sea Systems Command (NAVSEA)
APPLICANT(S)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	David J. Orlin (Westminster, Maryland); Kenneth M. Fischer (New Market, Maryland); Franz J. Riggieri (Catonsville, Maryland); Derek C. Fulk (Ellicott City, Maryland)
ABSTRACT	Methods and systems to detect changes in a region of space relative to baseline measurements, including to process data to detect potential objects, or contacts against a natural background environment, to characterize and geo-register the contacts, to compare and correlate the contacts with a database of known objects, and to report uncorrelated contacts as new objects in the space. Features disclosed herein may be implemented to process image data from a line-by-line image-generation system including, for example, side-looking sonar. Methods and system may be implemented with respect to multi-frequency band sonar data.
FILED	Thursday, August 06, 2009
APPL NO	12/536609
ART UNIT	3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Communications, electrical: Acoustic wave systems and devices 367/88
VIEW PATENT	@ USPTO: Full Text PDF

08189560 — Retransmission switch box

US 08189560	Taibi et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Daniel Taibi (Baltimore, Maryland); Robert Roberts (White Plains, Maryland); Eric Vandersall (Adelphi, Maryland)
ABSTRACT	An apparatus for use with a first data device, a second data device, and a third data device operable to generate one of directly and indirectly an interrupt signal and to disable one of directly and indirectly the interrupt signal. The apparatus includes a switch connectable to the first data device, the second data device, and the third data device, the switch in a first state connecting the first data device and the second data device, the switch in a second state being operable, upon detection by the switch of the interrupt signal, to disconnect automatically the first data device from the second data device and to connect automatically thereafter the first data device to said the data device.
FILED	Friday, May 30, 2008
APPL NO	12/130007
ART UNIT	2464 — Multiplex and VoIP
CURRENT CPC	Multiplex communications 370/351
VIEW PATENT	@ USPTO: Full Text PDF

08189643 — Sub-wavelength grating integrated VCSEL

US 08189643	Chang-Hasnain et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Connie J. Chang-Hasnain (Palo Alto, California); Michael Chung-Yi Huang (Taipei, Taiwan); Ye Zhou (Shanghai, China PRC); Carlos Fernando Rondina Mateus (Sao Jose de Campos, Brazil)
ABSTRACT	A vertical cavity surface emitting laser (VCSEL) is described using a sub-wavelength grating (SWG) structure that has a very broad reflection spectrum and very high reflectivity. The grating comprises segments of high and low refractive index materials with an index differential between the high and low index materials. By way of example, a SWG reflective structure is disposed over a low index cavity region and above another reflective layer (either SWG or DBR). In one embodiment, the SWG structure is movable, such as according to MEMS techniques, in relation to the opposing reflector to provide wavelength selective tuning. The SWG-VCSEL design is scalable to form the optical cavities for a range of SWG-VCSELs at different wavelengths, and wavelength ranges.
FILED	Monday, June 07, 2010
APPL NO	12/795641
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Coherent light generators 372/50.124
VIEW PATENT	@ USPTO: Full Text PDF

08189789 — Intrusion-tolerant group management for mobile ad-hoc networks

US 08189789	Coan et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	Telcordia Technologies, Inc. (Piscataway, New Jersey)
INVENTOR(S)	Brian A. Coan (Morris Plains, New Jersey); Jonathan Kirsch (Baltimore, Maryland)
ABSTRACT	An inventive system and method for intrusion-tolerant group management for a network is presented. The method comprises a client broadcasting a message request to controllers and validating the rekey messages received from the controllers, and controllers validating the client's broadcast message request and broadcasting proposals, collecting proposals, constructing threshold-signed proofs, updating the view umber, performing the client's message request, generating the rekey based on the valid proposals and transmitting the rekey to the client. Simultaneously, controllers send reconciliation messages to all controllers, based on which the membership state is updated. The client updates a shared key when a predetermined number of valid rekey messages are received. The controllers can communicate via a byzantine fault-tolerant agreement. The client can use its public key to decrypt the rekey and perform validation. The client's message request can be a join or a leave.
FILED	Tuesday, November 03, 2009
APPL NO	12/611493
ART UNIT	2439 — Cryptography and Security
CURRENT CPC	Cryptography 380/273
VIEW PATENT	@ USPTO: Full Text PDF

08189872 — Method for quantifying cell motility and cell migration

US 08189872	Beebe et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	David J. Beebe (Monona, Wisconsin); Ivar Meyvantsson (Madison, Wisconsin)
ABSTRACT	A method of quantifying cell migration of a cell population is provided. The method includes the step of patterning the cell population within a channel network in a first body. A first image of the cell population is obtained. Thereafter, a second image of the cell population is obtained after a first predetermined time period. The first and second images are compared in order to calculate a quantitative measure of the average directional migration of the cells population and a quantitative measure of the average motility of the cell population.
FILED	Thursday, October 11, 2007
APPL NO	11/870740
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/107
VIEW PATENT	@ USPTO: Full Text PDF

08189968 — Multimode interference coupler for use with slot photonic crystal waveguides

US 08189968	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S)	Board of Regents, The University of Texas (Austin, Texas)
INVENTOR(S)	Xiaonan Chen (Austin, Texas); Ray T. Chen (Austin, Texas)
ABSTRACT	The present invention provides an optical apparatus having a multimode interference coupler configured to optically couple a strip waveguide to a slot photonic crystal waveguide. The multimode interference coupler has a coupling efficiency to the slot photonic crystal waveguide greater than or equal to 90%, a width that is approximately equal to a defect width of the slot photonic crystal waveguide, a length that is equal to or less than 1.5 μm, and interfaces with the slot photonic crystal waveguide at an edge of a period that gives a termination parameter of approximately zero. The optical apparatus may also include an insulation gap disposed between the multimode interference coupler and the slot photonic crystal waveguide, wherein the length of the multimode interference coupler is reduced by approximately one half of a width of the insulation gap.
FILED	Friday, August 28, 2009
APPL NO	12/550186
ART UNIT	2883 — Optics
CURRENT CPC	Optical waveguides 385/15
VIEW PATENT	@ USPTO: Full Text PDF

08189981 — Stable lithium niobate waveguides, and methods of making and using same

US 08189981	Muller et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Heinrich G. Muller (Rancho Palos Verdes, California); Hyun I. Kim (Yorba Linda, California); Brendan J. Foran (Los Angeles, California)
ABSTRACT	The invention provides stable lithium niobate waveguides, and systems and methods for making same. In accordance with one aspect of the invention, a waveguide includes a lithium niobate substrate having an upper surface; and a soft proton-exchanged layer embedded within the substrate, the soft proton-exchanged layer formed by exposing the lithium niobate substrate to a proton exchange solution including a proton exchange acid and a lithium salt of the proton exchange acid at a temperature of less than an atmospheric boiling point of the solution, followed by annealing the lithium niobate substrate under a vapor pressure of water preselected to inhibit protons in the substrate from forming water and evaporating from the upper surface of the substrate. The preselected water vapor pressure may be between 0.1 atm and about 0.9 atm, for example, between about 0.4 atm and about 0.6 atm, in one embodiment about 0.47 atm.
FILED	Monday, November 23, 2009
APPL NO	12/624147
ART UNIT	2883 — Optics
CURRENT CPC	Optical waveguides 385/131
VIEW PATENT	@ USPTO: Full Text PDF

08190006 — Nozzle-based, vapor-phase, plume delivery structure for use in production of thin-film deposition layer

US 08190006	Wendt et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Global Solar Energy, Inc. (Tucson, Arizona)
INVENTOR(S)	Robert G. Wendt (Tucson, Arizona); Scott Wiedeman (Tucson, Arizona); Jeffrey S. Britt (Tucson, Arizona); Douglas G. Mason (Tucson, Arizona)
ABSTRACT	A vapor deposition source including a crucible configured to hold a quantity of molten constituent material and at least one nozzle to pass vapor evaporated from the molten constituent material out of the crucible.
FILED	Thursday, May 22, 2008
APPL NO	12/154548
ART UNIT	3742 — Optics
CURRENT CPC	Electric resistance heating devices 392/388
VIEW PATENT	@ USPTO: Full Text PDF

08190028 — Method and apparatus for treating a received signal to present a resulting signal with improved signal accuracy

US 08190028	Franklin
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	James D. Franklin (Manhattan Beach, California)
ABSTRACT	A signal treating apparatus for presenting an output signal representing an input signal over a signal range includes: (a) an input section receiving the input signal and presenting a first filtered signal limited to a first bandwidth at a first circuit locus; the input section presenting a second filtered signal limited to a second bandwidth at a second circuit locus; (b) an amplifying unit receiving the first filtered signal and presenting an increased gain signal at an amplifier output locus; (c) a detector coupled with the amplifier output locus and presenting third bandwidth-limited signal limited to a third bandwidth less than the first bandwidth at a third circuit locus; and (d) a combining section coupled with the second and third circuit loci and presenting a resulting signal related with the second filtered signal and the third filtered signal; said resultant signal being said output signal.
FILED	Thursday, September 25, 2008
APPL NO	12/238116
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Optical communications 398/95
VIEW PATENT	@ USPTO: Full Text PDF

08190305 — Hierarchical closed-loop control system for aircraft, missiles and munitions

US 08190305	Prince et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S)	Orbital Research Inc. (Cleveland, Ohio)
INVENTOR(S)	Troy S. Prince (Cleveland, Ohio); Richard Kolacinski (South Euclid, Ohio); Mehul Patel (Streetsboro, Ohio)
ABSTRACT	The present invention relates to a missile or aircraft with a hierarchical, modular, closed-loop flow control system and more particularly to aircraft or missile with a flow control system for enhanced aerodynamic control, maneuverability and stabilization. The present invention further relates to a method of operating the flow control system. Various embodiments of the flow control system of the present invention involve different elements including flow sensors, active flow control device or activatable flow effectors and logic devices with closed loop control architecture. The sensors of these various embodiments are used to estimate or determine flow conditions on the various surfaces of a missile or aircraft. The active flow control device or activatable flow effectors of these various embodiments create on-demand flow disturbances, preferably micro-disturbances, at different points along the various aerodynamic surfaces of the missile or aircraft to achieve a desired stabilization or maneuverability effect. The logic devices are embedded with a hierarchical control structure allowing for rapid, real-time control at the flow surface.
FILED	Friday, September 11, 2009
APPL NO	12/557599
ART UNIT	3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/3
VIEW PATENT	@ USPTO: Full Text PDF

08190366 — LC resonance probe for determining local plasma density

US 08190366	Boris et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David R. Boris (Washington, District of Columbia); David D. Blackwell (Alexandria, Virginia); David N. Walker (Arlington, Virginia); Richard F. Fernsler (Annandale, Virginia); Scott G. Walton (Fairfax, Virginia)
ABSTRACT	An apparatus and method for determining plasma parameters such as plasma electron density n_e. The probe apparatus includes an LC resonance probe comprising an inductive element and a capacitive element connected in series. The capacitive element of the probe can be in the form of a parallel plate capacitor, a cylindrical capacitor, a spherical capacitor, or any other suitable capacitor. The configuration of the probe apparatus gives it a characteristic resonance frequency ω_R0which can be determined by a circuit analysis device. When the capacitive element of the probe apparatus is placed in a plasma, the probe exhibits a new resonance frequency ω_R, which is different from ω_R0because of the dielectric constant ∈ of the plasma. The difference in resonance frequencies can be used to determine plasma density n_e, where $n_{e} = \frac{m_{e} ɛ_{0}}{e^{2}} (ω_{R}^{2} - ω_{R 0}^{2}) .$
FILED	Friday, September 30, 2011
APPL NO	13/250050
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/1
VIEW PATENT	@ USPTO: Full Text PDF

08190422 — Semantic cognitive map

US 08190422	Ascoli et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	George Mason Intellectual Properties, Inc. (Fairfax, Virginia)
INVENTOR(S)	Giorgio A. Ascoli (Fairfax Station, Virginia); Alexei Samsonovich (Fairfax, Virginia)
ABSTRACT	A semantic cognitive map created by associating each of a multitude of dictionary entries with a point among a multitude of points in a metric space, each of the dictionary entries associated with at least one onym, the at least one onym including at least one synonym or antonym, the metric space having a topology and metrics, the location of each of the multitude of points defined by a global minimum of an energy function of the multitude of points.
FILED	Tuesday, May 20, 2008
APPL NO	12/123812
ART UNIT	2626 — Selective Visual Display Systems
CURRENT CPC	Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/9
VIEW PATENT	@ USPTO: Full Text PDF

08190699 — System and method of multi-path data communications

US 08190699	McMillian et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Space and Missile Defense Command (SMDC) U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S)
ASSIGNEE(S)	Crossfield Technology LLC (Austin, Texas)
INVENTOR(S)	Brett McMillian (Austin, Texas); Gary McMillian (Austin, Texas); Dennis Ferguson (Austin, Texas)
ABSTRACT	In a particular embodiment, a multi-path bridge circuit includes a backplane input/output (I/O) interface to couple to a local backplane having at least one communication path to a processing node and includes at least one host interface adapted to couple to a corresponding at least one processor. The multi-path bridge circuit further includes logic adapted to identify two or more communication paths through the backplane interface to a destination memory, to divide a data block stored at a source memory into data block portions, and to transfer the data block portions in parallel from the source memory to the destination node via the identified two or more communication paths.
FILED	Monday, July 28, 2008
APPL NO	12/180631
ART UNIT	2457 — Computer Networks
CURRENT CPC	Electrical computers and digital processing systems: Multicomputer data transferring 79/212
VIEW PATENT	@ USPTO: Full Text PDF

08190824 — Cache line replacement monitoring and profiling

US 08190824	Shen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Xiaowei Shen (Hopewell Junction, New York); Yefim Shuf (Millwood, New York); Peter F. Sweeney (Spring Valley, New York)
ABSTRACT	Systems and methods for cache replacement monitoring (CRM) are provided. The system includes a monitored cache comprising a monitored cache line set, the monitored cache line set comprising at least one cache line capable of holding data of a monitored address; and a CRM mechanism operatively associated with the monitored cache. The CRM mechanism collects CRM information for the monitored address. The method includes the steps of collecting CRM information for a monitored address in a monitored cache; and recording the CRM information for the monitored address, when at least one of (1) the monitored address is cached in the monitored cache, (2) the monitored address is replaced in the monitored cache, (3) any cache line in a cache line set corresponding to the monitored address is cached in the monitored cache, and (4) any cache line in a cache line set corresponding to the monitored address is replaced in the monitored cache.
FILED	Monday, June 09, 2008
APPL NO	12/135592
ART UNIT	2187 — Computer Architecture and I/O
CURRENT CPC	Electrical computers and digital processing systems: Memory 711/133
VIEW PATENT	@ USPTO: Full Text PDF

08190943 — Systolic merge sorter

US 08190943	Song
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	William S. Song (Lexington, Massachusetts)
ABSTRACT	A sorter system includes a clock continuously generating a series of clock signals, a systolic array circuit, and control circuitry in communication with serial access memory that stores data items of a sequence to be sorted and with the systolic array circuit to supply thereto data items as input and to receive therefrom data items as output. The systolic array circuit includes at least one processing module and K−1 registers, where K is an integer value greater than two. Each processing module has at least one of the registers, each register for storing one data item. The control circuitry serially presents K data items for input to the systolic array circuit in synchronization with the clock signals. On the next clock cycle after the control circuitry presents to the systolic array circuit the last of the K data items, the data item of least value in the given subsequence is output.
FILED	Friday, March 13, 2009
APPL NO	12/403903
ART UNIT	2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electrical computers and digital processing systems: Support 713/500
VIEW PATENT	@ USPTO: Full Text PDF

08191139 — Intrusion detection report correlator and analyzer

US 08191139	Heimerdinger et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	Walter L. Heimerdinger (Minneapolis, Minnesota); Jon P. Schewe (Maple Grove, Minnesota)
ABSTRACT	A computer/computer network security alert management system aggregates information from multiple intrusion detectors. Utilizing reports from multiple intrusion detectors reduces the high false alarm rate experienced by individual detectors while also improving detection of coordinated attacks involving a series of seemingly harmless operations. An internal representation of a protected enclave is utilized, and intrusion detection system (IDS) information is correlated to accurately prioritize alerts. In one embodiment, the system is capable of utilizing data from most existing IDS products, with flexibility to add further IDS products.
FILED	Monday, December 20, 2004
APPL NO	11/017382
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Information security 726/23
VIEW PATENT	@ USPTO: Full Text PDF

RE043422 — Tunable optical local oscillator

US RE43422	Kozlowski et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	David A. Kozlowski (Redondo Beach, California); John A. Hurrell (Palos Verdes, California)
ABSTRACT	A tunable optical local oscillator is used for optical heterodyne signal detection using an electrooptic Mach-Zehnder modulator to produce a rapidly tunable optical signal from a tunable RF frequency generator. A combination of the Mach-Zehnder modulator and optical fibers for providing stimulated Brillouin scattering are used to suppress unwanted signals for providing a spectrally pure optical local oscillator waveform. Suppression of unwanted optical signals, up to 50 dB, generated by the Mach-Zehnder modulator is obtained, resulting in high spectral purity of the optical local oscillator waveform with an extended tuning range of the tunable optical oscillator equal to the operating bandwidth of up to 60 GHz of the Mach-Zehnder modulators.
FILED	Thursday, June 14, 2007
APPL NO	11/812100
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Coherent light generators 372/29.11
VIEW PATENT	@ USPTO: Full Text PDF

Department of Health and Human Services (HHS)

08186235 — Method and device for the collection of airborne particles and their concentration in small amounts of liquid

US 08186235	Mainelis
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC) National Institute for Occupational Safety and Health (NIOSH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S)	Gediminas Mainelis (Milltown, New Jersey)
ABSTRACT	A method and its possible embodiments are presented for collecting airborne biological and non-biological agents and concentrating them into small amounts of liquid. Airborne particles are drawn into the sampler and by the action of an electrostatic field are deposited on the collection electrode covered with superhydrophobic substance (surface contact angle >150°). At the end of the sampling period a small liquid droplet (5-60 μL) is injected at the top of the sampling chamber. Since the sampler is positioned at an angle to the horizontal, the droplet rolls-off of collection electrode's surface under the force of gravity and removes the deposited particles. The droplet is then collected by a liquid capture system. The particles concentrated in such small amounts of liquid facilitate sample analysis by various techniques. The suggested sampler's embodiments achieve sample concentration rates higher than 1×10⁶/min which will allow detection of very low particle concentrations.
FILED	Tuesday, June 23, 2009
APPL NO	12/490011
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/864.710
VIEW PATENT	@ USPTO: Full Text PDF

08187208 — Methods for assessment of pelvic organ conditions affecting the vagina

US 08187208	Egorov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)	Artann Laboratories Inc. (Trenton, New Jersey)
INVENTOR(S)	Vladimir Egorov (Princeton, New Jersey); Heather van Raalte (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey)
ABSTRACT	Methods for assessment of pelvic floor conditions based on tactile imaging are described. The vaginal wall is deformed using a transvaginal probe equipped with tactile pressure sensors and a motion tracking sensor. The vaginal wall coordinates and pressure patterns are obtained during the examination and used to build 3-D tactile image of the vagina and to calculate elasticity modulus profiles and spacing profiles along selected lines inside 3-D tactile image. The profile values at specified locations are then compared with thresholds or profiles for normal conditions of vagina and its support structures. Methods of the invention are disclosed to be used in assessing a risk of pelvic organ prolapse development, estimating an extent of pelvic floor organ traumatic damage after childbirth and estimating an improvement after an interventional procedure.
FILED	Friday, April 08, 2011
APPL NO	13/083494
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/591
VIEW PATENT	@ USPTO: Full Text PDF

08187209 — Movement disorder monitoring system and method

US 08187209	Giuffrida
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S)	Great Lakes Neurotechnologies Inc (Valley View, Ohio)
INVENTOR(S)	Joseph Giuffrida (North Royalton, Ohio)
ABSTRACT	The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.
FILED	Thursday, March 17, 2005
APPL NO	11/082668
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/595
VIEW PATENT	@ USPTO: Full Text PDF

08187257 — Optical devices and methods for selective and conventional photocoagulation of the retinal pigment epithelium

US 08187257	Lin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Charles P. Lin (Arlington, Massachusetts); Clemens Alt (Cambridge, Massachusetts)
ABSTRACT	The present invention provides devices and methods for applying radiation to the retina of a patient. In one embodiment, an apparatus includes a radiation source for generating a radiation beam suitable for absorption by retinal pigment epithelial cells. One or more optical components are included to direct the beam onto the retina. A scanner is optically coupled to the radiation source to control movement of the beam in two dimensions to allow a scan over the retina. A controller applies control signals to the scanner to adjust beam movement to illuminate a plurality of retinal locations in a temporal sequence according to a predefined pattern. The device can be operated in one mode to effect selective targeting of retinal pigment epithelial cells, or in another mode to effect thermal photocoagulation of the retina.
FILED	Monday, October 31, 2005
APPL NO	11/263677
ART UNIT	3769 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery 66/10
VIEW PATENT	@ USPTO: Full Text PDF

08187586 — Methods of inducing apoptosis in hyperproliferative cells

US 08187586	Brown et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Arthur M. Brown (Brecksville, Ohio); Barbara A. Wible (Cleveland, Ohio)
ABSTRACT	Methods of inducing apoptosis in hyperproliferative cells, particularly cancer cells are provided. Such method involves increasing the levels of a potassium channel modulatory protein in the cell. Examples of such proteins are native KChAP protein, a biologically active variant of native KChAP protein, or a biologically active KChAP-related protein (collectively referred to hereinafter as “KChAP protein”). In one embodiment, the cells are contacted with the KChAP protein under conditions permitting uptake of the protein by the cells. In another embodiment, the cells are contacted with (i) a nucleic acid encoding the KChAP protein, and (ii) a promoter active in the cancer cell, wherein the promoter is operably linked to the region encoding the KChAP protein, under conditions permitting the uptake of the nucleic acid by the cancer cell. Methods of detecting cancerous cells in a biological sample selected from the group consisting of a colorectal tissue sample or brain tissue sample are also provided. Such method comprises assaying for the presence of elevated levels of KChAP mRNA or KChAP protein in the sample.
FILED	Monday, February 23, 2004
APPL NO	10/784528
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/93.200
VIEW PATENT	@ USPTO: Full Text PDF

08187591 — Methods of treating coagulopathy

US 08187591	Marth et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Jamey D. Marth (Goleta, California); Prabhjit Kaur Grewal (Santa Barbara, California)
ABSTRACT	The invention provides compositions and methods for enhancing clearance of coagulation factors {e.g., VWF) and platelets from the blood stream of a patient in need thereof. The methods comprise administering to the patient a therapeutically effective amount of an agent that increases clearance of coagulation factors or platelets. Such an agent can be, for example, a neuraminidase.
FILED	Friday, October 10, 2008
APPL NO	12/681884
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/94.610
VIEW PATENT	@ USPTO: Full Text PDF

08187595 — Monoclonal antibodies for enhancing or inhibiting insulin-like growth factor-I

US 08187595	Clemmons et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	David R. Clemmons (Chapel Hill, North Carolina); Laura A. Maile (Chapel Hill, North Carolina)
ABSTRACT	The present invention provides αVβ3 integrin cysteine loop domain agonists and antagonists (including peptide agonists and antagonists and analogs thereof), along with methods of using the same.
FILED	Tuesday, July 07, 2009
APPL NO	12/498719
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/130.100
VIEW PATENT	@ USPTO: Full Text PDF

08187611 — Anti-peptide antibodies that cross react with protective antigen of Bacillus anthracis and uses thereof

US 08187611	Abboud et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)	Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S)	Nareen Abboud (New Rochelle, New York); Arturo Casadevall (New Rochelle, New York)
ABSTRACT	The present invention provides a purified peptide comprising at least one of the sequences LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a vaccine, a method to protect or treat an animal from anthrax toxin, a method of making a vaccine and the use of the peptide. The present invention also provides a monoclonal antibody that specifically binds to a peptide sequence comprising at least one of the following peptide sequences: LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a method to protect or treat an animal from anthrax toxin, a method of making a vaccine, a pharmaceutical composition, a method of making a pharmaceutical composition, and the use of the monoclonal antibody.
FILED	Tuesday, October 05, 2010
APPL NO	12/924813
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/246.100
VIEW PATENT	@ USPTO: Full Text PDF

08187616 — Method for silk fibroin gelation using sonication

US 08187616	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	Xiaoqin Wang (Malden, Massachusetts); Jon Kluge (Southborough, Massachusetts); Gary G. Leisk (Wilmington, Massachusetts); David L. Kaplan (Concord, Massachusetts)
ABSTRACT	This invention provides for a process of rapidly forming silk fibroin gelation through ultrasonication. Under the appropriate conditions, gelation can be controlled to occur within two hours after the ultrasonication treatment. Biological materials, including viable cells, or therapeutic agents can be encapsulated in the hydrogels formed from the process and be used as delivery vehicles.
FILED	Thursday, May 29, 2008
APPL NO	12/601845
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/400
VIEW PATENT	@ USPTO: Full Text PDF

08187639 — Amniotic membrane preparations and purified compositions and anti-angiogenesis treatment

US 08187639	Tseng et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Tissue Tech, Inc. (Miami, Florida)
INVENTOR(S)	Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Wei Li (Songgang Town, China PRC)
ABSTRACT	Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
FILED	Wednesday, September 27, 2006
APPL NO	11/535924
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/583
VIEW PATENT	@ USPTO: Full Text PDF

08187678 — Ultra-thin microporous/hybrid materials

US 08187678	Jiang et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Ying-Bing Jiang (Albuquerque, New Mexico); Joseph L. Cecchi (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico)
ABSTRACT	Ultra-thin hybrid and/or microporous materials and methods for their fabrication are provided. In one embodiment, the exemplary hybrid membranes can be formed including successive surface activation and reaction steps on a porous support that is patterned or non-patterned. The surface activation can be performed using remote plasma exposure to locally activate the exterior surfaces of porous support. Organic/inorganic hybrid precursors such as organometallic silane precursors can be condensed on the locally activated exterior surfaces, whereby ALD reactions can then take place between the condensed hybrid precursors and a reactant. Various embodiments can also include an intermittent replacement of ALD precursors during the membrane formation so as to enhance the hybrid molecular network of the membranes.
FILED	Friday, November 14, 2008
APPL NO	12/271719
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/535
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08187802 — Cell lines useful for assessing modulation of autophagy

US 08187802	White et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Eileen White (Princeton, New Jersey); Anne Marie Strohecker (New York, New York); Robin Mathew (Monroe, New Jersey); Cristina Karp (North Brunswick, New Jersey)
ABSTRACT	Methods for screening for modulators of autophagy are disclosed. Methods for identifying genes whose expression inhibits autophagy, as well as genes whose expression promotes autophagy, are disclosed. Also disclosed are methods for identifying compounds that stimulate autophagy, as well as compounds that inhibit autophagy. Cell lines that may be used in the methods of identification are also disclosed.
FILED	Thursday, November 19, 2009
APPL NO	12/622410
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

08187808 — Barriers for facilitating biological reactions

US 08187808	Kelso et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	David M. Kelso (Wilmette, Illinois); Kunal Sur (Evanston, Illinois); Zaheer Parpia (Evanston, Illinois)
ABSTRACT	The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or hydrophobic barriers in sample separation, purification, modification, and analysis processes.
FILED	Friday, February 27, 2009
APPL NO	12/395020
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
VIEW PATENT	@ USPTO: Full Text PDF

08187824 — Porphyrinic compounds for use in flow cytometry

US 08187824	Lindsey
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Jonathan S. Lindsey (Raleigh, North Carolina)
ABSTRACT	The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The method comprises utilizing as the detectable luminescent compound a compound comprising a porphyrinic macrocycle such as a porphyrin, chlorin, bacteriochlorin, or isobacteriochlorin. In particular embodiments, the detectable luminescent compound comprises a compound of the formula A-A′-Z—B′—B, wherein: A is a targeting group or member of a specific binding pair that specifically binds the detectable luminescent compound to the target compound, cell or particle; A′ is a linker group or covalent bond; B′ is a linker group or covalent bond; B is a water-soluble group; and Z is the porphyrinic macrocycle.
FILED	Thursday, November 30, 2006
APPL NO	12/095423
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.230
VIEW PATENT	@ USPTO: Full Text PDF

08188032 — G-CSF transferrin fusion proteins

US 08188032	Shen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	National Institutes of Health (NIH) (Bethesda, Maryland)
INVENTOR(S)	Wei-Chiang Shen (San Marino, California); Yun Bai (Tucker, Georgia); David Ann (Arcadia, California); Adam Widera (Long Beach, California)
ABSTRACT	A polypeptide comprising a G-CSF domain operably linked to a Tf domain, wherein the ability of the polypeptide to be transported into a cell expressing a TfR gene or the ability of the polypeptide to be transported across a cell expressing a TfR gene via transcytosis is higher than that of the G-CSF domain alone.
FILED	Friday, October 08, 2004
APPL NO	10/575033
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/1.100
VIEW PATENT	@ USPTO: Full Text PDF

08188041 — Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents

US 08188041	Tracey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Feinstein Institute for Medical Research (Manhasset, New York)
INVENTOR(S)	Kevin J. Tracey (Old Greenwich, Connecticut); Huan Yang (Douglaston, New York)
ABSTRACT	The invention features a method of treating an inflammatory condition in an individual, comprising administering an agent inhibits the interaction between a Toll-like receptor 2 (TLR2) and a high mobility group B (HMGB) polypeptide to the individual. The invention also features methods for identifying agents that inhibit the interaction between TLR2 and HMGB.
FILED	Tuesday, January 19, 2010
APPL NO	12/689623
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/12
VIEW PATENT	@ USPTO: Full Text PDF

08188051 — Metadherin polypeptides, encoding nucleic acids and methods of use

US 08188051	Ruoslahti et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	The Burnham Institute (La Jolla, California)
INVENTOR(S)	Erkki Ruoslahti (Rancho Santa Fe, California); Darren M. Brown (Carlsbad, California)
ABSTRACT	Metadherin, a protein that controls metastasis, and variants of metadherin are described. DNA sequences encoding the same and methods of production are described. Therapies involving the application of metadherin, binding agents that bind to metadherin, such as antibodies, and expression modulating agents, such as siRNA, are described. The use of metadherin or metadherin variants for delivering desired substances to particular lung tissue is described. A method of diagnosing metastatic cells based on the presence of metadherin is described.
FILED	Tuesday, December 16, 2008
APPL NO	12/336409
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/19.400
VIEW PATENT	@ USPTO: Full Text PDF

08188055 — Inactivators of O6-alkylguanine-DNA alkyltransferase

US 08188055	Moschel et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S)	Robert C. Moschel (Frederick, Maryland); Matthew Karl Moschel, legal representative (Baltimore, Maryland); Anthony E. Pegg (Hershey, Pennsylvania); Sahar Javanmard (Potomac, Maryland); Natalia Loktionova (Elizabeth Town, Pennsylvania); Gary Pauly (Frederick, Maryland)
ABSTRACT	Disclosed are compounds that are AGT inactivators that include a folate residue, e.g., a compound of formula (I), wherein X¹, X², R¹, and R²are as described herein. Also disclosed is a pharmaceutical composition comprising a compound of the invention and a pharmaceutically acceptable carrier. Also disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells and inactivating AGT in a tumor cell. The methods comprise, inter alia, administering a compound or pharmaceutically acceptable salt of formula (I).
FILED	Wednesday, March 12, 2008
APPL NO	12/597773
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/43
VIEW PATENT	@ USPTO: Full Text PDF

08188058 — Use of toll-like receptor-9 agonists, toll-like receptor-4 antagonists, and/or nuclear oligomerization domain-2 agonists for the treatment or prevention of toll-like receptor-4-associated disorders

US 08188058	Hackam et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	David J. Hackam (Pittsburgh, Pennsylvania); Steven C. Gribar (Monroeville, Pennsylvania)
ABSTRACT	The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.
FILED	Thursday, April 17, 2008
APPL NO	12/104816
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44.R00
VIEW PATENT	@ USPTO: Full Text PDF

08188062 — Delivery of DNA or RNA via gap junctions from host cells to target cells and a cell-based delivery system for antisense or siRNA

US 08188062	Brink et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York); The Research Foundation of State University of New York (Albany, New York)
INVENTOR(S)	Peter R. Brink (Setauket, New York); Michael R. Rosen (New York, New York); Richard B. Robinson (Cresskill, New Jersey); Ira S. Cohen (Stony Brook, New York); Arthur Grollman (Setauket, New York)
ABSTRACT	A method of delivering an oligonucleotide or a plasmid expressing an oligonucleotide into a target cell comprises introducing an oligonucleotide into a donor cell, particularly a stem cell, and contacting the target cell with the donor cell under conditions permitting the donor cell to form a gap junction with the target cell, whereby the oligonucleotide or a product of the oligonucleotide is delivered into the target cell from the donor cell.
FILED	Friday, October 22, 2010
APPL NO	12/910346
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44
VIEW PATENT	@ USPTO: Full Text PDF

08188063 — Use of adenosine A_2Amodulators to treat spinal cord injury

US 08188063	Li et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Yuesheng Jason Li (Charlottesville, Virginia); Joel M. Linden (Charlottesville, Virginia); Jayson M. Rieger (Charlottesville, Virginia)
ABSTRACT	The present invention is a method for treatment or prevention of injury to nerve cells. The method can use at least one A_2Areceptor modulator to prevent injury to or enhance the healing of the injured cells.
FILED	Tuesday, June 19, 2007
APPL NO	11/765320
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/46
VIEW PATENT	@ USPTO: Full Text PDF

08188065 — Boldine compounds for promoting bone growth

US 08188065	Ellies et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)
ASSIGNEE(S)	OsteoGeneX Inc. (Kansas City, Kansas)
INVENTOR(S)	Debra Ellies (Parkville, Missouri); William Rosenberg (Overland Park, Missouri)
ABSTRACT	The present invention provides a method of promoting bone growth in a subject in need thereof, by administering to the subject a therapeutically effective amount of a compound of Formula I. The present invention also provides methods for the treatment of renal disease and cancer.
FILED	Thursday, October 01, 2009
APPL NO	12/571623
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/167
VIEW PATENT	@ USPTO: Full Text PDF

08188072 — Benzodiazepinone compounds useful in the treatment of skin conditions

US 08188072	Glick
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Gary D. Glick (Ann Arbor, Michigan)
ABSTRACT	The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.
FILED	Thursday, November 06, 2008
APPL NO	12/266239
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/221
VIEW PATENT	@ USPTO: Full Text PDF

08188080 — VHR protein tyrosine phosphatase inhibitors, compositions and methods of use

US 08188080	Mustelin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S)	Tomas Mustelin (La Jolla, California); Lutz Tautz (La Jolla, California)
ABSTRACT	Disclosed herein are Vaccinia H1-related (VHR) protein tyrosine phosphatase (PTP) inhibitors that provide a method for treating cancer.
FILED	Friday, October 17, 2008
APPL NO	12/253804
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/236.500
VIEW PATENT	@ USPTO: Full Text PDF

08188089 — Tylophorine analogs as antitumor agents

US 08188089	Lee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Kuo-Hsiung Lee (Chapel Hill, North Carolina); Linyi Wei (Chapel Hill, North Carolina); Kenneth F. Bastow (Chapel Hill, North Carolina); Arnold Brossi (Bethesda, Maryland); Tian-Shung Wu (Tianan, Taiwan)
ABSTRACT	Compounds of Formula I are described: preferably subject to the proviso that either (a) R²and R³together form —O—CH(R¹⁰)—O—, or (b) R⁵and R⁶together form —O—CH(R¹⁰)—O—, wherein R¹⁰is H, halo, or loweralkyl. Pharmaceutical salts, formulations, and methods of using the same in the treatment of cancer are also described.
FILED	Wednesday, December 20, 2006
APPL NO	12/096950
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/254.110
VIEW PATENT	@ USPTO: Full Text PDF

08188096 — Protein kinase targeted therapeutics

US 08188096	Watterson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	D. Martin Watterson (Chicago, Illinois); Linda J. Van Eldik (Chicago, Illinois)
ABSTRACT	The present invention relates to compositions and methods useful in treating diseases and disorders related to protein kinases. In particular, the present invention relates to compositions and methods useful for targeting protein kinases related to mitogen activated protein kinase (MAPK) pathways (e.g., p38 MAPK, JNK, ERK, and upstream and downstream protein kinases) and/or casein kinase (CK) pathways (e.g., CK1δ, and upstream and downstream protein kinases), and diseases and disorders related to MAPK pathways (e.g., p38 MAPK, JNK, ERK, and upstream and downstream protein kinases) and/or CK pathways (e.g., CK1δ, and upstream and downstream protein kinases).
FILED	Thursday, February 24, 2011
APPL NO	13/034411
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/256
VIEW PATENT	@ USPTO: Full Text PDF

08188130 — Anti-cancer hydantoin compounds and methods

US 08188130	Shah et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Louisiana at Monroe (Monroe, Louisiana)
INVENTOR(S)	Girish Shah (Monroe, Louisiana); Khalid El Sayed (Louisiana, Louisiana)
ABSTRACT	The present invention relates to methods of either treating or preventing cancer and novel compositions relevant to that treatment and prevention. More particularly, this invention relates to compounds which share features with (Z)-5-(4-hydroxybenzylidene)imidazolidine-2,4-dione and (Z)-5-(4-S-ethylbenzylidene)imidazolidine-2,4-dione and anti-cancer uses for those compounds. Embodiments of the present invention include methods that have anti-cancer effects including anti-metastatic, anti-growth, and anti-invasive activities.
FILED	Thursday, May 15, 2008
APPL NO	12/120756
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/389
VIEW PATENT	@ USPTO: Full Text PDF

08188131 — Compounds that enhance Atoh1 expression

US 08188131	Edge et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) U.S. Public Health Service (USPHS)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Albert Edge (Brookline, Massachusetts); Sang-Jun Jeon (Seoul, South Korea); Kathleen Seyb (Allston, Massachusetts); Marcie Glicksman (Winchester, Massachusetts); Lixin Qiao (Tewksbury, Massachusetts); Gregory D. Cuny (Somerville, Massachusetts)
ABSTRACT	This invention generally provides compounds, pharmaceutical compositions, and methods for their use, which include methods that result in increased expression in an Atoh1 gene (e.g., Hath1) in a biological cell. More specifically, the invention relates to the treatment of diseases and/or disorders that would benefit from increased Atoh1 expression, e.g., a hearing impairment or imbalance disorder associated with a loss of auditory hair cells, or a disorder associated with abnormal cellular proliferation.
FILED	Monday, February 09, 2009
APPL NO	12/368173
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/394
VIEW PATENT	@ USPTO: Full Text PDF

08188141 — Isomigrastatin analogs in the treatment of cancer

US 08188141	Danishefsky et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Sloan-Kettering Institute for Cancer Research (New York, New York)
INVENTOR(S)	Samuel J. Danishefsky (Englewood, New Jersey); Mihirbaran Mandal (New York, New York); David C. Dorn (New York, New York); Malcolm A. S. Moore (New York, New York)
ABSTRACT	The present invention provides compounds having formula (I): (I) wherein n, R₁-R₅, R_a-R_b, Q, Y₁and Y₂are as defined herein; and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders involving increased angiogenesis.
FILED	Friday, September 23, 2005
APPL NO	11/663580
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/431
VIEW PATENT	@ USPTO: Full Text PDF

08188147 — Therapeutic methods employing nitric oxide precursors

US 08188147	Summar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Marshall L. Summar (Brentwood, Tennessee); Brian W. Christman (Nashville, Tennessee); Frederick E. Barr (Nashville, Tennessee)
ABSTRACT	Isolated polynucleotide molecules and peptides encoded by these molecules are used in the analysis of human carbamyl phosphate synthetase I phenotypes, as well as in diagnostic and therapeutic applications, relating to a human carbamyl phosphate synthetase I polymorphism. By analyzing genomic DNA or amplified genomic DNA, or amplified cDNA derived from mRNA, it is possible to type a human carbamyl phosphate synthetase I with regard to the human carbamyl phosphate synthetase I polymorphism, for example, in the context of diagnosing and treating hepatic veno-occlusive disease (HVOD) associated with bone marrow transplants.
FILED	Friday, May 16, 2008
APPL NO	12/122117
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/565
VIEW PATENT	@ USPTO: Full Text PDF

08188214 — Brachyury polypeptides and methods for use

US 08188214	Schlom et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Jeffrey Schlom (Potomac, Maryland); Claudia M. Palena (Rockville, Maryland); Andrei P. Kozlov (St. Petersburg, Russian Federation); Kwong-yok Tsang (Bethesda, Maryland)
ABSTRACT	It is disclosed herein that Brachyury is expressed in human tumors, specifically in tumors of the small intestine, stomach, kidney, bladder, uterus, ovary, and testes, as well as in lung, colon and prostate carcinomas. Immunogenic Brachyury polypeptides are disclosed herein. These polypeptides can be used in diagnostic assays for Brachyury expression, as well as for inducing an immune response to Brachyury. Polynucleotides encoding the immunogenic Brachyury polypeptides, vectors including these polypeptides, host cells transformed with these vectors, and methods of using these polypeptides, polynucleotides, vectors, and host cells are provided. Methods of diagnosing a Brachyury-expressing cancer are also provided. Exemplary cancers include lung, colon, small intestine, stomach, kidney, bladder, uterus, ovary, and testes and prostate cancers. Methods of treating cancer are also disclosed.
FILED	Wednesday, February 27, 2008
APPL NO	12/528796
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300
VIEW PATENT	@ USPTO: Full Text PDF

08188220 — Methods and compositions related to targeting wounds, regenerating tissue, and tumors

US 08188220	Ruoslahti et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S)	Erkki Ruoslahti (LaJolla, California); Tero Jarvinen (LaJolla, California)
ABSTRACT	Disclosed are compositions and methods useful for targeting regenerating tissue, wounds, and tumors. The compositions and methods are based on peptide sequences that selectively bind to and home to regenerating tissue, wound sites, and tumors in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to regenerating tissue, wound sites, and tumors in animals.
FILED	Thursday, December 06, 2007
APPL NO	11/951819
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/328
VIEW PATENT	@ USPTO: Full Text PDF

08188245 — Enduracidin biosynthetic gene cluster from streptomyces fungicidicus

US 08188245	Yin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) U.S. State Government State of Oregon
APPLICANT(S)
ASSIGNEE(S)	State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Xihou Yin (Corvallis, Oregon); T. Mark Zabriskie (Corvallis, Oregon)
ABSTRACT	This disclosure describes the molecular cloning of an enduracidin biosynthetic gene cluster from Streptomyces fungicidicus, and characterization of individual genes in the gene cluster and the proteins encoded thereby. An enduracidin gene cluster is located within a 116 kilobases genetic locus and includes 25 open reading frames (ORFs). An additional 23 ORFs flank the disclosed enduracidin biosynthetic gene cluster. Enduracidin analogs and a method for producing them by manipulation of the enduracidin gene cluster and specific genes therein are also disclosed.
FILED	Monday, October 01, 2007
APPL NO	12/443161
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Organic compounds 536/23.100
VIEW PATENT	@ USPTO: Full Text PDF

08188246 — Nucleic acid and amino acid sequences encoding high-level expressor factor VIII polypeptides and methods of use

US 08188246	Lollar
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Expression Therapeutics LLC (Tucker, Georgia)
INVENTOR(S)	John S. Lollar (Decatur, Georgia)
ABSTRACT	Methods and compositions are provided that allow for high-level expression of a factor VIII polypeptide. More specifically, methods and compositions are provided comprising nucleic acid and amino acid sequences comprising a modified factor VIII that result in high-level expression of the polypeptide. The methods and compositions of the invention find use in the treatment of factor VIII deficiency including, for example, hemophilia A.
FILED	Friday, December 11, 2009
APPL NO	12/636424
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/23.100
VIEW PATENT	@ USPTO: Full Text PDF

08188252 — Rad51 derived cancer cell specific promoters for targeted anti-cancer therapy

US 08188252	Hine et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Christopher M. Hine (Rochester, New York); Andrei Seluanov (Rochester, New York); Vera Gorbunova (Rochester, New York)
ABSTRACT	Provided are compositions and methods for inhibiting growth of cancer cells. The method of the invention relates to delivering to cells an effective amount of a composition that contains a polynucleotide having a Rad51 promoter or a polynucleotide having at least 95% similarity to a Rad51 promoter. The Rad51 promoter is operably linked to a coding region for a cytotoxic agent. In vitro and in vivo results demonstrating effectiveness of the polynucleotides of the invention are presented.
FILED	Tuesday, November 17, 2009
APPL NO	12/620103
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/24.100
VIEW PATENT	@ USPTO: Full Text PDF

08188289 — Conformationally restricted urea inhibitors of soluble epoxide hydrolase

US 08188289	Hammock et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Bruce D. Hammock (Davis, California); Paul D. Jones (Matawan, New Jersey); Christophe Morisseau (West Sacramento, California); Huazhang Huang (Davis, California); Hsing-Ju Tsai (Davis, California); Richard Gless (Hayward, California)
ABSTRACT	Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
FILED	Tuesday, March 13, 2007
APPL NO	11/685674
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Organic compounds 546/245
VIEW PATENT	@ USPTO: Full Text PDF

08188298 — Synthetic route to ABCD-porphyrins

US 08188298	Lindsey et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Jonathan S. Lindsey (Raleigh, North Carolina); Dilek Dogutan Kiper (Raleigh, North Carolina)
ABSTRACT	A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described.
FILED	Tuesday, June 28, 2011
APPL NO	13/170492
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Organic compounds 548/402
VIEW PATENT	@ USPTO: Full Text PDF

08188302 — Hydroamination of alkenes

US 08188302	Liu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Zhijian Liu (Urbana, Illinois); John F. Hartwig (Champaign, Illinois)
ABSTRACT	A method includes reacting an amino group, a composition including rhodium and an organic ligand, and a substrate having structural formula (I) in a reaction mixture. R¹is an organic group including a sp³carbon atom bonded to C^A. R²is selected from the group consisting of hydrogen, methyl, and an organic group including a sp³carbon atom bonded to C^A. R³and R⁴independently are selected from the group consisting of hydrogen, methyl, and an organic group including a sp³carbon atom bonded to C^B. The method further includes forming a hydroaminated product in the reaction mixture.
FILED	Tuesday, October 14, 2008
APPL NO	12/251062
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Organic compounds 549/220
VIEW PATENT	@ USPTO: Full Text PDF

08188306 — Heat shock protein 90 inhibitors

US 08188306	Blagg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S)	University of Kansas (Lawrence, Kansas)
INVENTOR(S)	Brian S. J. Blagg (Lawrence, Kansas); Gang Shen (Ballwin, Missouri)
ABSTRACT	Novel compounds useful for inhibiting the 90kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol.
FILED	Wednesday, September 30, 2009
APPL NO	12/570804
ART UNIT	1621 — Organic Chemistry
CURRENT CPC	Organic compounds 560/9
VIEW PATENT	@ USPTO: Full Text PDF

08188423 — Method and apparatus for ion fragmentation in mass spectrometry

US 08188423	Doroshenko et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S)	Science and Engineering Services, Inc. (Columbia, Maryland)
INVENTOR(S)	Vladimir M. Doroshenko (Sykesville, Maryland); Vadym D. Berkout (Rockville, Maryland); Andrey Vilkov (Tustin, California)
ABSTRACT	A method for fragmentation of analyte ions for mass spectroscopy and a system for mass spectroscopy. The method produces gas-phase analyte ions, produces gas-phase odd-electron containing species separately from the analyte ions, and mixes the gas-phase analyte ions and the odd-electron containing species at substantially atmospheric pressure conditions to produce fragment ions prior to introduction into a mass spectrometer. The system includes a gas-phase analyte ion source, a gas-phase odd-electron containing species source separate from the gas-phase analyte ion source, a mixing region where the gas-phase analyte ions and the odd-electron containing species are mixed at substantially atmospheric pressure to produce fragment ions of the analyte ions, a mass spectrometer having an entrance where at least a portion of the fragment ions are introduced into a vacuum of the mass spectrometer, and a detector in the mass spectrometer which determines a mass to charge ratio analysis of the fragment ions.
FILED	Friday, May 21, 2010
APPL NO	12/784532
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/281
VIEW PATENT	@ USPTO: Full Text PDF

08188735 — Resolution enhanced T1-insensitive steady state imaging (RE-TOSSI)

US 08188735	Derakhshan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	Case Western Reserve University (, None)
INVENTOR(S)	Jamal J. Derakhshan (Cleveland Heights, Ohio); Mark A. Griswold (Shaker Heights, Ohio); Jeffrey L. Duerk (Avon Lake, Ohio)
ABSTRACT	Systems, methods, and other embodiments associated with RE-TOSSI are described. One system embodiment includes an MRI apparatus configured to produce a RE-TOSSI pulse sequence and to acquire T2-weighted images in response to the RE-TOSSI pulse sequence. An example RE-TOSSI pulse sequence includes a TOSSI portion and a non-inverting, non-TOSSI portion.
FILED	Wednesday, October 29, 2008
APPL NO	12/290343
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/307
VIEW PATENT	@ USPTO: Full Text PDF

08189192 — Volume phase grating spectrometers and related methods and systems

US 08189192	Huening et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S)	Bioptigen, Inc. (Durham, North Carolina)
INVENTOR(S)	Pete Huening (Clayton, North Carolina); Robert H. Hart (Cary, North Carolina); Eric L. Buckland (Hickory, North Carolina)
ABSTRACT	A Spectrometer is provided including a camera and an axial symmetric camera mount configured to receive the camera and to rotate. The spectrometer furthers include an input for providing optical radiation to a spectrometer system; a diffraction grating for dispersing the optical radiation along a prescribed plane; at least one lens for focusing wavelength-dispersed light onto at least one array of a detector of optical radiation, wherein the camera has at least one linear array of elements for detecting optical radiation; a mechanical housing, wherein the axial symmetric camera mount is configured to couple the camera to the mechanical housing; and a means for rotating the camera coupled to the mechanical housing about an axis. Related systems and methods are also provided.
FILED	Thursday, June 25, 2009
APPL NO	12/491546
ART UNIT	2877 — Optics
CURRENT CPC	Optics: Measuring and testing 356/328
VIEW PATENT	@ USPTO: Full Text PDF

08189204 — Surface wave enabled darkfield aperture

US 08189204	Cui et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Xiquan Cui (Pasadena, California); Xin Heng (Somerville, Massachusetts); Changhuei Yang (Pasadena, California); Axel Scherer (Laguna Beach, California); Demetri Psaltis (Lausanne, Switzerland); Guoan Zheng (Pasadena, California)
ABSTRACT	Embodiments of the present invention relate to a surface wave enabled darkfield aperture structure comprising an aperture layer, a aperture in the aperture layer and a plurality of grooves around the aperture. The aperture layer has a first and second surface. The plurality of grooves is in the first surface. A surface wave propagates along at least the first surface. The plurality of grooves is configured to generate a darkfield at the aperture by modifying the surface wave to cancel out direct transmission of a uniform incident light field received by the aperture.
FILED	Wednesday, June 02, 2010
APPL NO	12/792059
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/521
VIEW PATENT	@ USPTO: Full Text PDF

08189872 — Method for quantifying cell motility and cell migration

US 08189872	Beebe et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	David J. Beebe (Monona, Wisconsin); Ivar Meyvantsson (Madison, Wisconsin)
ABSTRACT	A method of quantifying cell migration of a cell population is provided. The method includes the step of patterning the cell population within a channel network in a first body. A first image of the cell population is obtained. Thereafter, a second image of the cell population is obtained after a first predetermined time period. The first and second images are compared in order to calculate a quantitative measure of the average directional migration of the cells population and a quantitative measure of the average motility of the cell population.
FILED	Thursday, October 11, 2007
APPL NO	11/870740
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/107
VIEW PATENT	@ USPTO: Full Text PDF

08189890 — Computer-aided classification of anomalies in anatomical structures

US 08189890	Summers et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Ronald M. Summers (Potomac, Maryland); Marek Franaszek (Gaithersburg, Maryland); Gheorghe Iordanescu (Rockville, Maryland)
ABSTRACT	Candidate anomalies in an anatomical structure are processed for classification. For example, false positives can be reduced by techniques related to the anomaly's neck, wall thickness associated with the anomaly, template matching performed for the anomaly, or some combination thereof. The various techniques can be combined for use in a classifier, which can determine whether the anomaly is of interest. For example, a computed tomography scan of a colon can be analyzed to determine whether a candidate anomaly is a polyp. The technologies can be applied to a variety of other scenarios involving other anatomical structures.
FILED	Monday, November 30, 2009
APPL NO	12/627958
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/128
VIEW PATENT	@ USPTO: Full Text PDF

08189893 — Methods, systems, and computer program products for binary multiplexing x-ray radiography

US 08189893	Zhang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Jian Zhang (Chapel Hill, North Carolina); Jianping Lu (Chapel Hill, North Carolina); Otto Z. Zhou (Chapel Hill, North Carolina); David Lalush (Cary, North Carolina)
ABSTRACT	Methods, systems, and computer program products for binary multiplexing x-ray radiography are disclosed. According to one aspect, the subject matter described herein can include irradiating an object with composite x-ray beams including signals based on a predetermined binary transform. Further, the subject matter described herein can include detecting x-ray intensities associated with the signals of the composite x-ray beams. An inverse binary transform can be applied to the detected x-ray intensities associated with the signals of the composite x-ray beams to recover the signals of the composite x-ray beams.
FILED	Monday, May 21, 2007
APPL NO	11/804897
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/131
VIEW PATENT	@ USPTO: Full Text PDF

08189900 — Image-based methods for measuring global nuclear patterns as epigenetic markers of cell differentiation

US 08189900	Sammak et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S)	Tha Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts); University of Pittsburgh-of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Paul J. Sammak (Pittsburgh, Pennsylvania); Rami Mangoubi (Newton, Massachusetts); Mukund Desai (Needham, Massachusetts); Teresa M. Erb (Pittsburgh, Pennsylvania); Nathan Lowry (Lexington, Massachusetts)
ABSTRACT	The invention provides methods for determining the differentiation state of cells. The methods include non-invasive, non-perturbing, automatable, and quantitative methods of analysis of cell colonies, individual cells, and/or cellular structures.
FILED	Monday, March 14, 2011
APPL NO	13/047591
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/133
VIEW PATENT	@ USPTO: Full Text PDF

08190244 — Gated optical coherence tomography (OCT) environmental chamber

US 08190244	Rollins et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Andrew Rollins (Highland Heights, Ohio); Michael Jenkins (Parma, Ohio); Osman Chughtai (Canton, Ohio)
ABSTRACT	Systems, methods, and other embodiments associated with gated optical coherence tomography (OCT) are described. One example method includes generating an image control signal to control an OCT apparatus to acquire an image of an embryonic heart at a specified point in time during a cardiac cycle of the embryonic heart. The method may also include controlling the OCT apparatus to acquire the image based on the image control signal. In different examples, the image may be acquired in vivo or from an excised heart that is paced. The OCT apparatus and the embryonic heart may be housed in an environmental chamber having a set of controllable environmental factors. Therefore, the method may include detecting and controlling the set of controllable environmental factors.
FILED	Wednesday, January 23, 2008
APPL NO	12/009992
ART UNIT	3737 — Semiconductors/Memory
CURRENT CPC	Surgery 6/476
VIEW PATENT	@ USPTO: Full Text PDF

08190249 — Multi-parametric quantitative analysis of bioelectrical signals

US 08190249	Gharieb et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)
ASSIGNEE(S)	Infinite Biomedical Technologies, LLC (Baltimore, Maryland)
INVENTOR(S)	Reda R. Gharieb (Baltimore, Maryland); Manan Hathi (Cockeysville, Maryland); Santosh Venkatasha (Baltimore, Maryland); David Sherman (Parkville, Maryland); Neil Rothman (Baltimore, Maryland); Margaret Natarajan (San Marino, California); Ananth Naturajan (San Marino, California)
ABSTRACT	Certain embodiments relate to a method for determining a condition of a subject, including obtaining a signal, the signal including a plurality of determinable parameters. The method also includes determining at least two of the plurality of determinable parameters from the signal, to yield determined parameters. The method also includes applying a weighting factor to each of the determined parameters to yield weighted parameters, and combining the weighted parameters to determine a numeric value relating to the condition of the subject. Other embodiments are described and claimed.
FILED	Tuesday, August 01, 2006
APPL NO	11/496925
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/544
VIEW PATENT	@ USPTO: Full Text PDF

08190267 — Fitting a neural prosthesis using impedance and electrode height

US 08190267	Greenberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S)	Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S)	Robert J. Greenberg (Los Angeles, California); Ione Fine (Seattle, Washington); Arup Roy (Valencia, California); Matthew J. McMahon (Los Angeles, California); Mark S. Humayun (Glendale, California); James David Weiland (Valencia, California); Alan M. Horsager (Los Angeles, California); Dao Min Zhou (Saugus, California); Amy Hines (Monterey Park, California); Sumit Yadav (Los Angeles, California); Rongqing Dai (Valencia, California)
ABSTRACT	The invention is a method of automatically adjusting an electrode array to the neural characteristics of an individual subject. The response to electrical neural stimulation varies from subject to subject. Measure of impedance may be used to predict the electrode height from the neural tissue and, thereby, predict the threshold of perception. Alternatively, electrode height may be measured directly to predict the threshold of perception. Also, impedance measurement may be used to quickly identify defective electrodes and proper electrode placement.
FILED	Friday, October 26, 2007
APPL NO	11/925285
ART UNIT	3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/54
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

08186151 — Method to monitor HC-SCR catalyst NOx reduction performance for lean exhaust applications

US 08186151	Viola et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S)	Michael B. Viola (Macomb Township, Michigan); Steven J. Schmieg (Troy, Michigan); Thompson M. Sloane (Oxford, Michigan); David L. Hilden (Shelby Township, Michigan); Patricia A. Mulawa (Clinton Township, Michigan); Jong H. Lee (Rochester Hills, Michigan); Shi-Wai S. Cheng (Troy, Michigan)
ABSTRACT	A method for initiating a regeneration mode in selective catalytic reduction device utilizing hydrocarbons as a reductant includes monitoring a temperature within the aftertreatment system, monitoring a fuel dosing rate to the selective catalytic reduction device, monitoring an initial conversion efficiency, selecting a determined equation to estimate changes in a conversion efficiency of the selective catalytic reduction device based upon the monitored temperature and the monitored fuel dosing rate, estimating changes in the conversion efficiency based upon the determined equation and the initial conversion efficiency, and initiating a regeneration mode for the selective catalytic reduction device based upon the estimated changes in conversion efficiency.
FILED	Tuesday, June 09, 2009
APPL NO	12/480932
ART UNIT	3748 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Power plants 060/295
VIEW PATENT	@ USPTO: Full Text PDF

08186166 — Hybrid two fuel system nozzle with a bypass connecting the two fuel systems

US 08186166	Varatharajan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Balachandar Varatharajan (Cincinnati, Ohio); Willy Steve Ziminsky (Simpsonville, South Carolina); Ertan Yilmaz (Albany, New York); Benjamin Lacy (Greer, South Carolina); Baifang Zuo (Simpsonville, South Carolina); William David York (Greer, South Carolina)
ABSTRACT	A hybrid fuel combustion nozzle for use with natural gas, syngas, or other types of fuels. The hybrid fuel combustion nozzle may include a natural gas system with a number of swozzle vanes and a syngas system with a number of co-annular fuel tubes.
FILED	Tuesday, July 29, 2008
APPL NO	12/181329
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/748
VIEW PATENT	@ USPTO: Full Text PDF

08186731 — Tamper indicating seal

US 08186731	Romero et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Juan A. Romero (Albuquerque, New Mexico); Charles A. Walker (Albuquerque, New Mexico); Dianna S. Blair (Albuquerque, New Mexico); Connie C. Bodmer (Albuquerque, New Mexico)
ABSTRACT	Seals have a flexible wire that can be looped through a hasp-like device. The seals include a body having a recess, a plug insertable into the recess and a snap ring for fastening the plug to the body. The plug and/or body can have access holes for inserting the wire into the recess. “Teeth” on the outer diameter and through-holes through the thickness of the snap ring allow for passing the ends of the flexible wire from the recess through the snap ring. The ends of the wire can be folded back over the snap ring and into engagement with the teeth. Assembly of the seal causes the ends of the wire to be securely fastened between the teeth of the snap ring and the sidewall of the recess. Seals can include a plug and/or body made of a frangible material such as glass, ceramic, glass-ceramic or brittle polymer.
FILED	Tuesday, April 14, 2009
APPL NO	12/423263
ART UNIT	3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Closure fasteners 292/307.R00
VIEW PATENT	@ USPTO: Full Text PDF

08186953 — Multiple piece turbine blade

US 08186953	Kimmel
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Keith D Kimmel (Jupiter, Florida)
ABSTRACT	A turbine rotor blade with a spar and shell construction, the spar including an internal cooling supply channel extending from an inlet end on a root section and ending near the tip end, and a plurality of external cooling channels formed on both side of the spar, where a middle external cooling channel is connected to the internal cooling supply channels through a row of holes located at a middle section of the channels. The spar and the shell are held together by hooks that define serpentine flow passages for the cooling air and include an upper serpentine flow circuit and a lower serpentine flow circuit. the serpentine flow circuits all discharge into a leading edge passage or a trailing edge passage.
FILED	Wednesday, June 17, 2009
APPL NO	12/486179
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Fluid reaction surfaces 416/97.R00
VIEW PATENT	@ USPTO: Full Text PDF

08187252 — Shape memory system with integrated actuation using embedded particles

US 08187252	Buckley et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Patrick R. Buckley (New York, New York); Duncan J. Maitland (Pleasant Hill, California)
ABSTRACT	A shape memory material with integrated actuation using embedded particles. One embodiment provides a shape memory material apparatus comprising a shape memory material body and magnetic pieces in the shape memory material body. Another embodiment provides a method of actuating a device to perform an activity on a subject comprising the steps of positioning a shape memory material body in a desired position with regard to the subject, the shape memory material body capable of being formed in a specific primary shape, reformed into a secondary stable shape, and controllably actuated to recover the specific primary shape; including pieces in the shape memory material body; and actuating the shape memory material body using the pieces causing the shape memory material body to be controllably actuated to recover the specific primary shape and perform the activity on the subject.
FILED	Thursday, August 06, 2009
APPL NO	12/536670
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery 64/508
VIEW PATENT	@ USPTO: Full Text PDF

08187398 — Energetic composite and system with enhanced mechanical sensitivity to initiation of self-sustained reaction

US 08187398	Gash et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Alexander E. Gash (Brentwood, California); Troy W. Barbee, Jr. (Palo Alto, California)
ABSTRACT	An energetic composition and system using amassed energetic multilayer pieces which are formed from the division, such as for example by cutting, scoring, breaking, crushing, shearing, etc., of a mechanically activatable monolithic energetic multilayer(s) (e.g. macro-scale sheets of multilayer films), for enhancing the sensitivity of the energetic composite and system to mechanical initiation of self-sustained reaction. In particular, mechanical initiation of the energetic composition may be achieved with significantly lower mechanical energy inputs than that typically required for initiating the monolithic energetic multilayers from which it is derived.
FILED	Friday, May 18, 2007
APPL NO	11/804454
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Explosive and thermic compositions or charges 149/109.400
VIEW PATENT	@ USPTO: Full Text PDF

08187673 — Methods utilizing scanning probe microscope tips and products thereof or produced thereby

US 08187673	Mirkin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Chad A. Mirkin (Wilmette, Illinois); Richard Piner (Des Plaines, Illinois); Seunghun Hong (Chicago, Illinois)
ABSTRACT	The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). DPN utilizes a scanning probe microscope (SPM) tip (e.g., an atomic force microscope (AFM) tip) as a “pen,” a solid-state substrate (e.g., gold) as “paper,” and molecules with a chemical affinity for the solid-state substrate as “ink.” Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly write patterns consisting of a relatively small collection of molecules in submicrometer dimensions, making DPN useful in the fabrication of a variety of microscale and nanoscale devices. The invention also provides substrates patterned by DPN, including submicrometer combinatorial arrays, and kits, devices and software for performing DPN. The invention further provides a method of performing AFM imaging in air. The method comprises coating an AFM tip with a hydrophobic compound, the hydrophobic compound being selected so that AFM imaging performed using the coated AFM tip is improved compared to AFM imaging performed using an uncoated AFM tip. Finally, the invention provides AFM tips coated with the hydrophobic compounds.
FILED	Wednesday, October 31, 2007
APPL NO	11/933251
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/256
VIEW PATENT	@ USPTO: Full Text PDF

08187678 — Ultra-thin microporous/hybrid materials

US 08187678	Jiang et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Ying-Bing Jiang (Albuquerque, New Mexico); Joseph L. Cecchi (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico)
ABSTRACT	Ultra-thin hybrid and/or microporous materials and methods for their fabrication are provided. In one embodiment, the exemplary hybrid membranes can be formed including successive surface activation and reaction steps on a porous support that is patterned or non-patterned. The surface activation can be performed using remote plasma exposure to locally activate the exterior surfaces of porous support. Organic/inorganic hybrid precursors such as organometallic silane precursors can be condensed on the locally activated exterior surfaces, whereby ALD reactions can then take place between the condensed hybrid precursors and a reactant. Various embodiments can also include an intermittent replacement of ALD precursors during the membrane formation so as to enhance the hybrid molecular network of the membranes.
FILED	Friday, November 14, 2008
APPL NO	12/271719
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/535
VIEW PATENT	@ USPTO: Full Text PDF

08187720 — Corrosion resistant neutron absorbing coatings

US 08187720	Choi et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California); Sandia National Laboratories (Livermore, California)
INVENTOR(S)	Jor-Shan Choi (El Cerrito, California); Joseph C. Farmer (Tracy, California); Chuck K. Lee (Hayward, California); Jeffrey Walker (Gaithersburg, Maryland); Paige Russell (Las Vegas, Nevada); Jon Kirkwood (Saint Leonard, Maryland); Nancy Yang (Lafayette, California); Victor Champagne (Oxford, Pennsylvania)
ABSTRACT	A method of forming a corrosion resistant neutron absorbing coating comprising the steps of spray or deposition or sputtering or welding processing to form a composite material made of a spray or deposition or sputtering or welding material, and a neutron absorbing material. Also a corrosion resistant neutron absorbing coating comprising a composite material made of a spray or deposition or sputtering or welding material, and a neutron absorbing material.
FILED	Thursday, November 09, 2006
APPL NO	11/595623
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/553
VIEW PATENT	@ USPTO: Full Text PDF

08187731 — Metal ferrite spinel energy storage devices and methods for making and using same

US 08187731	Weimer et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S)	Alan W. Weimer (Niwot, Colorado); Christopher Perkins (Boulder, Colorado); Jonathan Scheffe (Westminster, Colorado); Steven M. George (Boulder, Colorado); Paul Lichty (Westminster, Colorado)
ABSTRACT	1-100 nm metal ferrite spinel coatings are provided on substrates, preferably by using an atomic layer deposition process. The coatings are able to store energy such as solar energy, and to release that stored energy, via a redox reaction. The coating is first thermally or chemically reduced. The reduced coating is then oxidized in a second step to release energy and/or hydrogen, carbon monoxide or other reduced species.
FILED	Wednesday, May 05, 2010
APPL NO	12/774286
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/702
VIEW PATENT	@ USPTO: Full Text PDF

08187746 — Surface modification agents for lithium batteries

US 08187746	Chen et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Zonghai Chen (Bolingbrook, Illinois); Khalil Amine (Oakbrook, Illinois); Ilias Belharouak (Bolingbrook, Illinois)
ABSTRACT	An active material for an electrochemical device may have a surface modification agent that is a silane, organometallic compound, or a mixture of two or more of such compounds. Both negative and positive electrodes may be prepared from the surface modified active materials. The surface of an electrode may be modified by adding the surface modification agent to a non-aqueous electrolyte used in constructing a battery. An electrode or active material may be modified with a surface modification agent in either the gas phase or in solution. Slurries of the active agent may be prepared and the surface modification agent added, the slurry then be used to cast an electrode that is then dried.
FILED	Wednesday, May 13, 2009
APPL NO	12/454173
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/209
VIEW PATENT	@ USPTO: Full Text PDF

08188363 — Module level solutions to solar cell polarization

US 08188363	Xavier et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)
ASSIGNEE(S)	SunPower Corporation (San Jose, California)
INVENTOR(S)	Grace Xavier (Fremont, California); Bo Li (San Jose, California)
ABSTRACT	A solar cell module includes interconnected solar cells, a transparent cover over the front sides of the solar cells, and a backsheet on the backsides of the solar cells. The solar cell module includes an electrical insulator between the transparent cover and the front sides of the solar cells. An encapsulant protectively packages the solar cells. To prevent polarization, the insulator has resistance suitable to prevent charge from leaking from the front sides of the solar cells to other portions of the solar cell module by way of the transparent cover. The insulator may be attached (e.g., by coating) directly on an underside of the transparent cover or be a separate layer formed between layers of the encapsulant. The solar cells may be back junction solar cells.
FILED	Friday, August 07, 2009
APPL NO	12/538034
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Batteries: Thermoelectric and photoelectric 136/251
VIEW PATENT	@ USPTO: Full Text PDF

08188761 — Soft error detection for latches

US 08188761	Fleischer et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Bruce M. Fleischer (Bedford Hills, New York); Michael K. Gschwind (Chappaqua, New York)
ABSTRACT	A system and method for soft error detection in digital ICs is disclosed. The system includes an observing circuit coupled to a latch, which circuit is capable of a response upon a state change of the latch. The system further includes synchronized clocking provided to the latch and to the observing circuit. For the latch, the clocking defines a window in time during which the latch is prevented from receiving data, and in a synchronized manner the clocking is enabling a response in the observing circuit. The clocking is synchronized in such a manner that the circuit is enabled for its response only inside the window when the latch is prevented from receiving data. The system may also have additional circuits that are respectively coupled to latches, with each the additional circuit and its respective latch receiving the synchronized clocking Responses of a plurality of circuits may be coupled in a configuration corresponding to a logical OR.
FILED	Monday, February 14, 2011
APPL NO	13/026472
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Electronic digital logic circuitry 326/9
VIEW PATENT	@ USPTO: Full Text PDF

08188841 — Method of remote powering and detecting multiple UWB passive tags in an RFID system

US 08188841	Dowla et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Farid U. Dowla (Castro Valley, California); Faranak Nekoogar (San Ramon, California); David M. Benzel (Livermore, California); Gregory E. Dallum (Livermore, California); Alex Spiridon (Palo Alto, California)
ABSTRACT	A new Radio Frequency Identification (RFID), tracking, powering apparatus/system and method using coded Ultra-wideband (UWB) signaling is introduced. The proposed hardware and techniques disclosed herein utilize a plurality of passive UWB transponders in a field of an RFID-radar system. The radar system itself enables multiple passive tags to be remotely powered (activated) at about the same time frame via predetermined frequency UWB pulsed formats. Once such tags are in an activated state, an UWB radar transmits specific “interrogating codes” to put predetermined tags in an awakened status. Such predetermined tags can then communicate by a unique “response code” so as to be detected by an UWB system using radar methods.
FILED	Friday, August 31, 2007
APPL NO	11/897773
ART UNIT	2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Communications: Electrical 340/10.340
VIEW PATENT	@ USPTO: Full Text PDF

08189186 — Signal enhancement using a switchable magnetic trap

US 08189186	Beer
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC. (Livermore, California)
INVENTOR(S)	Neil Reginald Beer (Pleasanton, California)
ABSTRACT	A system for analyzing a sample including providing a microchannel flow channel; associating the sample with magnetic nanoparticles or magnetic polystyrene-coated beads; moving the sample with said magnetic nanoparticles or magnetic polystyrene-coated beads in the microchannel flow channel; holding the sample with the magnetic nanoparticles or magnetic polystyrene-coated beads in a magnetic trap in the microchannel flow channel; and analyzing the sample obtaining an enhanced analysis signal. An apparatus for analysis of a sample includes magnetic particles connected to the sample, a microchip, a flow channel in the microchip, a source of carrier fluid connected to the flow channel for moving the sample in the flow channel, an electromagnet trap connected to the flow line for selectively magnetically trapping the sample and the magnetic particles, and an analyzer for analyzing the sample.
FILED	Thursday, December 27, 2007
APPL NO	11/965598
ART UNIT	2877 — Optics
CURRENT CPC	Optics: Measuring and testing 356/244
VIEW PATENT	@ USPTO: Full Text PDF

08189426 — Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture

US 08189426	West et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	Phillip B. West (Idaho Falls, Idaho); Stephen R. Novascone (Idaho Falls, Idaho); Jerry P. Wright (Idaho Falls, Idaho)
ABSTRACT	Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture are described. According to one embodiment, an earth analysis method includes engaging a device with the earth, analyzing the earth in a single substantially lineal direction using the device during the engaging, and providing information regarding a subsurface feature of the earth using the analysis.
FILED	Tuesday, August 23, 2011
APPL NO	13/215474
ART UNIT	3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Communications, electrical: Acoustic wave systems and devices 367/41
VIEW PATENT	@ USPTO: Full Text PDF

08189494 — System and method for merging clusters of wireless nodes in a wireless network

US 08189494	Budampati et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	Ramakrishna S. Budampati (Maple Grove, Minnesota); Patrick S. Gonia (Maplewood, Minnesota); Soumitri N. Kolavennu (Blaine, Minnesota); Arun V. Mahasenan (Kerala, India)
ABSTRACT	A system includes a first cluster having multiple first wireless nodes. One first node is configured to act as a first cluster master, and other first nodes are configured to receive time synchronization information provided by the first cluster master. The system also includes a second cluster having one or more second wireless nodes. One second node is configured to act as a second cluster master, and any other second nodes configured to receive time synchronization information provided by the second cluster master. The system further includes a manager configured to merge the clusters into a combined cluster. One of the nodes is configured to act as a single cluster master for the combined cluster, and the other nodes are configured to receive time synchronization information provided by the single cluster master.
FILED	Monday, May 11, 2009
APPL NO	12/464002
ART UNIT	2467 — Multiplex and VoIP
CURRENT CPC	Multiplex communications 370/254
VIEW PATENT	@ USPTO: Full Text PDF

08190242 — Portable laser synthesizer for high-speed multi-dimensional spectroscopy

US 08190242	Demos et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Stavros G. Demos (Livermore, California); Miroslav Y. Shverdin (Sunnyvale, California); Michael D. Shirk (Brentwood, California)
ABSTRACT	Portable, field-deployable laser synthesizer devices designed for multi-dimensional spectrometry and time-resolved and/or hyperspectral imaging include a coherent light source which simultaneously produces a very broad, energetic, discrete spectrum spanning through or within the ultraviolet, visible, and near infrared wavelengths. The light output is spectrally resolved and each wavelength is delayed with respect to each other. A probe enables light delivery to a target. For multidimensional spectroscopy applications, the probe can collect the resulting emission and deliver this radiation to a time gated spectrometer for temporal and spectral analysis.
FILED	Wednesday, July 22, 2009
APPL NO	12/507585
ART UNIT	3768 — Semiconductors/Memory
CURRENT CPC	Surgery 6/473
VIEW PATENT	@ USPTO: Full Text PDF

08190295 — Apparatus and method for modifying the operation of a robotic vehicle in a real environment, to emulate the operation of the robotic vehicle operating in a mixed reality environment

US 08190295	Garretson et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Justin R. Garretson (Albuquerque, New Mexico); Eric P. Parker (Albuquerque, New Mexico); T. Scott Gladwell (Albuquerque, New Mexico); J. Brian Rigdon (Edgewood, New Mexico); Fred J. Oppel, III (Albuquerque, New Mexico)
ABSTRACT	Apparatus and methods for modifying the operation of a robotic vehicle in a real environment to emulate the operation of the robotic vehicle in a mixed reality environment include a vehicle sensing system having a communications module attached to the robotic vehicle for communicating operating parameters related to the robotic vehicle in a real environment to a simulation controller for simulating the operation of the robotic vehicle in a mixed (live, virtual and constructive) environment wherein the affects of virtual and constructive entities on the operation of the robotic vehicle (and vice versa) are simulated. These effects are communicated to the vehicle sensing system which generates a modified control command for the robotic vehicle including the effects of virtual and constructive entities, causing the robot in the real environment to behave as if virtual and constructive entities existed in the real environment.
FILED	Thursday, April 30, 2009
APPL NO	12/433347
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Generic control systems or specific applications 7/245
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

08187366 — Natural gas desulfurization

US 08187366	Yang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S)	Ralph T. Yang (Ann Arbor, Michigan); Yuhe Wang (Ann Arbor, Michigan); Luis Amestica (Santiago, Chile)
ABSTRACT	A method for desulfurizing natural gas includes contacting the natural gas with an adsorbent which preferentially adsorbs at least one of hydrogen sulfide, COS, sulfur odorants, or combinations thereof, at a selected temperature and pressure, thereby producing desulfurized natural gas and an at least one of hydrogen sulfide/COS/sulfur odorant/combinations thereof-rich adsorbed component. The adsorbent includes a copper species adapted to form π-complexation bonds and direct metal-sulfur bonds with the at least one of hydrogen sulfide, COS, sulfur odorants, or combinations thereof, and wherein the preferential adsorption occurs by π-complexation and direct metal-sulfur bonding.
FILED	Monday, November 03, 2008
APPL NO	12/263844
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Gas separation: Processes 095/135
VIEW PATENT	@ USPTO: Full Text PDF

08187441 — Electrochemical pump

US 08187441	Evans et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S)	Christine E. Evans (Fayetteville, Arkansas); Forrest W. Payne (Fayetteville, Arkansas); Carl A. Koval (Arvada, Colorado); Richard D. Noble (Boulder, Colorado); Mya A. Norman (Springdale, Arkansas)
ABSTRACT	The invention provides electrochemically-based methods and devices for producing fluid flow and/or changes in fluid pressure. In the methods and devices of the invention, current passes through a divided electrochemical cell. Adjacent compartments of the cell are divided by an ionically conducting separator. Each compartment includes an electrode and an electrolyte solution or ionic liquid. The electrolyte solution(s) or ionic liquid(s) and the ionically conducting separator are selected to obtain the desired relationship between the current through the cell and the fluid flowrate and/or change in fluid pressure.
FILED	Tuesday, August 25, 2009
APPL NO	12/546826
ART UNIT	1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Chemistry: Electrical and wave energy 24/518
VIEW PATENT	@ USPTO: Full Text PDF

08187500 — Biphasic inks

US 08187500	Lewis et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Jennifer A. Lewis (Urbana, Illinois); Qi Li (Champaign, Illinois); Ranjeet Rao (Mountain View, California)
ABSTRACT	A biphasic ink comprises a plurality of attractive particles, a plurality of repulsive particles, and a carrier liquid.
FILED	Friday, November 14, 2008
APPL NO	12/271832
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Compositions 252/500
VIEW PATENT	@ USPTO: Full Text PDF

08187808 — Barriers for facilitating biological reactions

US 08187808	Kelso et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	David M. Kelso (Wilmette, Illinois); Kunal Sur (Evanston, Illinois); Zaheer Parpia (Evanston, Illinois)
ABSTRACT	The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or hydrophobic barriers in sample separation, purification, modification, and analysis processes.
FILED	Friday, February 27, 2009
APPL NO	12/395020
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
VIEW PATENT	@ USPTO: Full Text PDF

08187887 — Method and apparatus for determining radiation

US 08187887	Swager et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Timothy M. Swager (Newton, Massachusetts); Jose M. Lobez (Boston, Massachusetts)
ABSTRACT	The present invention relates to devices, systems, and methods for determination of ionizing radiation. In some embodiments, the devices comprise nanocomposite materials containing nanostructures (e.g., carbon nanotubes) dispersed in radiation sensitive polymers. In some cases, the device may include a conductive pathway that may be affected upon exposure to ionizing radiation. Embodiments described herein may provide inexpensive, large area, low power, and highly sensitive radiation detection materials/devices.
FILED	Wednesday, October 06, 2010
APPL NO	12/899201
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/58
VIEW PATENT	@ USPTO: Full Text PDF

08187903 — Method of epitaxially growing piezoresistors

US 08187903	Yama et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	Robert Bosch GmbH (Stuttgart, Germany)
INVENTOR(S)	Gary Yama (Mountain View, California); Beth Pruitt (San Francisco, California); Arnoldus Alvin Barlian (Palo Alto, California)
ABSTRACT	A method of forming a device with a piezoresistor is disclosed herein. In one embodiment, the method includes providing a substrate, etching a trench in the substrate to form a vertical wall, growing a piezoresistor layer epitaxially on the vertical wall, and separating the vertical wall from an underlying layer of the substrate that extends along a horizontal plane such that the piezoresistor layer is movable with respect to the underlying layer within the horizontal plane.
FILED	Tuesday, January 13, 2009
APPL NO	12/353080
ART UNIT	2894 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/52
VIEW PATENT	@ USPTO: Full Text PDF

08188200 — Process for preparation of polyolefins via living coordinative chain transfer polymerization

US 08188200	Sita et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	University of Maryland, College Park (College Park, Maryland)
INVENTOR(S)	Lawrence R. Sita (Silver Spring, Maryland); Wei Zhang (Gaithersburg, Maryland)
ABSTRACT	Disclosed is a method of producing a polyolefin composition comprising contacting a metallocene pre-catalyst, co-catalyst, and a stoichiometric excess of a metal alkyl; adding a first olefin monomer; and polymerizing the first monomer for a time sufficient to form the polyolefin. The method allows for the use of minimum amounts of activating co-catalyst and metallocene pre-catalyst. Also disclosed is a method of producing a block polyolefin composition comprising contacting a metallocene pre-catalyst, a co-catalyst, and a stoichiometric excess of a metal alkyl; adding a first olefin monomer; polymerizing the first monomer for a time sufficient to form the polyolefin; adding a second monomer; and polymerizing the second olefin monomer for a time sufficient to form said block polyolefin composition. Also disclosed are amorphous atactic polymer and copolymer compositions made according to the present invention.
FILED	Monday, November 10, 2008
APPL NO	12/742055
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 526/161
VIEW PATENT	@ USPTO: Full Text PDF

08189956 — Optical device for correcting geostationary satellite imagery for earth curvature effects

US 08189956	Johnson
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) National Center for Atmospheric Research (NCAR) Federally Funded Research and Development Center (FFRDC) Operated by University Corporation for Atmospheric Research (UCAR) at Boulder, CO
APPLICANT(S)
ASSIGNEE(S)	University Corporation for Atmospheric Research (Boulder, Colorado)
INVENTOR(S)	David B. Johnson (Boulder, Colorado)
ABSTRACT	An optical adapter for an imaging system correcting images of spherical or near spherical bodies such as the earth during satellite image collection. An imaging system includes an image collector that collects a two-dimensional image of the body from a distance above the body such as from a satellite in geostationary orbit. The collected image is disk shaped and includes distortion due to earth curvature, primarily in the form of a loss of resolution due to the foreshortening of earth features in a radial direction extending outward from the center of the image disk. The optical adapter receives the collected image, transforms the collected image to correct the distortion, and outputs a corrected image with essentially uniform spatial resolution across the areas for which the correction is applied. An image sensor such as charge-coupled device array senses the corrected image and creates a digital representation of the corrected image.
FILED	Monday, March 08, 2010
APPL NO	12/719111
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/275
VIEW PATENT	@ USPTO: Full Text PDF

08190633 — Enabling provenance management for pre-existing applications

US 08190633	Freire et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)
ASSIGNEE(S)	The University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Juliana Freire (Salt Lake City, Utah); Claudio T. Silva (Salt Lake City, Utah); Steven P. Callahan (Centerville, Utah); Carlos E. Scheidegger (Salt Lake City, Utah); Huy T. Vo (Murray, Utah)
ABSTRACT	A method of providing provenance management for a pre-existing application is provided. A provenance data selection is received. The provenance data selection indicates provenance data to present to a user. The provenance data is presented to the user as a version tree comprising a plurality of connected nodes. A node selection is received. The node selection indicates a node selected from the version tree. One or more nodes from a root node of the plurality of connected nodes to the node selected from the version tree are identified. One or more action parameters associated with the identified one or more nodes are identified. An action parameter of the one or more action parameters is associated with a previous interaction with a pre-existing application. Presentation of a state of the pre-existing application associated with the node selected from the version tree is triggered.
FILED	Monday, June 16, 2008
APPL NO	12/140110
ART UNIT	2159 — Data Bases & File Management
CURRENT CPC	Data processing: Database and file management or data structures 77/778
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

08187865 — Nanowire sensor, sensor array, and method for making the same

US 08187865	Yun et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Minhee Yun (La Crescenta, California); Nosang Myung (Rosemead, California); Richard Vasquez (Altadena, California); Margie Homer (Pasadena, California); Margaret Ryan (Pasadena, California); Shiao-Pin Yen (Altadena, California); Jean-Pierre Fleurial (Altadena, California); Ratnakumar Bugga (Arcadia, California); Daniel Choi (Los Angeles, California); William Goddard (Pasadena, California); Abhijit Shevade (Pasadena, California); Mario Blanco (Temple City, California); Tahir Cagin (Arcadia, California); Wely Floriano (Pasadena, California)
ABSTRACT	The present invention relates to a nanowire sensor and method for forming the same. More specifically, the nanowire sensor comprises at least one nanowire formed on a substrate, with a sensor receptor disposed on a surface of the nanowire, thereby forming a receptor-coated nanowire. The nanowire sensor can be arranged as a sensor sub-unit comprising a plurality of homogeneously receptor-coated nanowires. A plurality of sensor subunits can be formed to collectively comprise a nanowire sensor array. Each sensor subunit in the nanowire sensor array can be formed to sense a different stimulus, allowing a user to sense a plurality of stimuli. Additionally, each sensor subunit can be formed to sense the same stimuli through different aspects of the stimulus. The sensor array is fabricated through a variety of techniques, such as by creating nanopores on a substrate and electrodepositing nanowires within the nanopores.
FILED	Friday, May 29, 2009
APPL NO	12/455186
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/287.200
VIEW PATENT	@ USPTO: Full Text PDF

08188430 — Omnidirectional monitoring using near-infrared electromagnetic radiation

US 08188430	Mian
FUNDED BY	National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC)
APPLICANT(S)
ASSIGNEE(S)	International Electronic Machines Corporation (Troy, New York)
INVENTOR(S)	Zahid F. Mian (Loudonville, New York)
ABSTRACT	A monitoring device includes an imaging device sensitive to visible and near-infrared electromagnetic radiation. The monitoring device is configured to concurrently direct omnidirectional visible and near-infrared electromagnetic radiation onto the imaging device without using any moving parts. The monitoring device also can include multiple sources of near-infrared electromagnetic radiation, which can be sequentially operated to illuminate regions of a monitored area to improve the imaged data. The monitoring device can acquire additional data, such as acoustic data or identification data of a target, and can process the acquired data to detect any targets that may be present and evaluate an alarm condition.
FILED	Friday, May 22, 2009
APPL NO	12/470518
ART UNIT	2884 — Optics
CURRENT CPC	Radiant energy 250/330
VIEW PATENT	@ USPTO: Full Text PDF

08189877 — Remote sensing analysis of forest disturbances

US 08189877	Asner
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	Carnegie Institution of Washington (Washington, District of Columbia)
INVENTOR(S)	Gregory P. Asner (Half Moon Bay, California)
ABSTRACT	The present invention provides systems and methods to automatically analyze Landsat satellite data of forests. The present invention can easily be used to monitor any type of forest disturbance such as from selective logging, agriculture, cattle ranching, natural hazards (fire, wind events, storms), etc. The present invention provides a large-scale, high-resolution, automated remote sensing analysis of such disturbances.
FILED	Thursday, October 19, 2006
APPL NO	12/083833
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/110
VIEW PATENT	@ USPTO: Full Text PDF

08189956 — Optical device for correcting geostationary satellite imagery for earth curvature effects

US 08189956	Johnson
FUNDED BY	National Aeronautics and Space Administration (NASA) National Science Foundation (NSF) National Center for Atmospheric Research (NCAR) Federally Funded Research and Development Center (FFRDC) Operated by University Corporation for Atmospheric Research (UCAR) at Boulder, CO
APPLICANT(S)
ASSIGNEE(S)	University Corporation for Atmospheric Research (Boulder, Colorado)
INVENTOR(S)	David B. Johnson (Boulder, Colorado)
ABSTRACT	An optical adapter for an imaging system correcting images of spherical or near spherical bodies such as the earth during satellite image collection. An imaging system includes an image collector that collects a two-dimensional image of the body from a distance above the body such as from a satellite in geostationary orbit. The collected image is disk shaped and includes distortion due to earth curvature, primarily in the form of a loss of resolution due to the foreshortening of earth features in a radial direction extending outward from the center of the image disk. The optical adapter receives the collected image, transforms the collected image to correct the distortion, and outputs a corrected image with essentially uniform spatial resolution across the areas for which the correction is applied. An image sensor such as charge-coupled device array senses the corrected image and creates a digital representation of the corrected image.
FILED	Monday, March 08, 2010
APPL NO	12/719111
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/275
VIEW PATENT	@ USPTO: Full Text PDF

Department of Agriculture (USDA)

08187423 — Fiber reinforced composites

US 08187423	Glenn et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Gregory M. Glenn (American Canyon, California); Charles N. Ludvik (Moraga, California)
ABSTRACT	In one aspect, the invention is directed to an efficient and economical process for dispersing fiber in water and clay. In another aspect, the process for dispersing fiber in water and clay is used in methods of making fiber reinforced composite products. In another aspect, the dispersed fiber/clay material is formulated to make products which include, but which are not limited to, fiber reinforced thermoplastic composites, paperboard products, kitty litter, and/or lightweight building materials comprising fiber.
FILED	Tuesday, May 09, 2006
APPL NO	11/431496
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Paper making and fiber liberation 162/181.800
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

08189178 — Method for multi-spectral detection of aerosols

US 08189178	Henning et al.
FUNDED BY	Department of Homeland Security (DHS) Science and Technology Directorate (DHS-ST)
APPLICANT(S)
ASSIGNEE(S)	Foster-Miller, Inc. (Waltham, Massachusetts)
INVENTOR(S)	Patrick F. Henning (Concord, Massachusetts); Aniruddha S. Weling (Framingham, California); Suneet Chadha (Westford, Massachusetts); Jay D. Eversole (Woodbridge, Virginia)
ABSTRACT	A system and method for sampling constituents in air including counting particles in the air to be sampled; collecting samples of accumulated particles; measuring UV response of a sample of accumulated particles only if the particle count exceeds a predetermined threshold; measuring IR response of that sample; and indicating a threat alarm if the IR response matches that of a target within a predetermined threshold.
FILED	Monday, June 22, 2009
APPL NO	12/456740
ART UNIT	2877 — Optics
CURRENT CPC	Optics: Measuring and testing 356/51
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

08190353 — Airspace design evaluation

US 08190353	White et al.
FUNDED BY	Department of Transportation (USDOT) Federal Aviation Administration (FAA)
APPLICANT(S)
ASSIGNEE(S)	The MITRE Corporation (McLean, Virginia)
INVENTOR(S)	Michael J. White (Sterling, Virginia); Robert P. Bearer (Winchester, Virginia); Carla Ximena Gladstone (Bethesda, Maryland); James M. Reed (Arlington, Virginia); Steven R. Kalbaugh, Sr. (Boca Raton, Florida); Patrick L. Jones (Vienna, Virginia)
ABSTRACT	A computer based method, system and computer program product to assign a quality metric to an airspace design and optionally to compare it against design metrics, to determine a comparative quality metric. Factors contributing to quality of the airspace sector design are identified via user input and quantified to calculate a quality metric for the airspace sector design as a function of the quantified factors. Categories for each of the identified factors, and parameters for each of the identified categories are also identified via user input. Each parameter has an associated weight and a range of thresholds with associated multipliers. An associated multiplier from the range of thresholds for each identified parameter is also identified. The identified multiplier is multiplied with the associated weight for each identified parameter. The products for each identified parameter are then summed to obtain a quality metric.
FILED	Monday, August 28, 2006
APPL NO	11/510781
ART UNIT	3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/122
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

08188219 — Bone morphogenic protein binding peptide

US 08188219	Murray et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Samuel S. Murray (Saugus, California); Keyvan Behnam (Red Bank, New Jersey); Elsa J. Brochmann-Murray (Saugus, California)
ABSTRACT	A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the over-all osteogenic activity of rgBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
FILED	Friday, January 28, 2005
APPL NO	10/587313
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

08187923 — Laser release process for very thin Si-carrier build

US 08187923	Andry et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Paul Stephen Andry (Yorktown Heights, New York); Leena Paivikki Buchwalter (Hopewell Junction, New York); Matthew J. Farinelli (Riverdale, New York); Sherif A. Goma (White Plains, New York); Raymond R. Horton (Dover Plains, New York); Edmund J. Sprogis (Underhill, Vermont)
ABSTRACT	A laser release and glass chip removal process for a integrated circuit module avoiding carrier edge cracking is provided.
FILED	Thursday, July 03, 2008
APPL NO	12/167745
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/118
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

08187208 — Methods for assessment of pelvic organ conditions affecting the vagina

US 08187208	Egorov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)	Artann Laboratories Inc. (Trenton, New Jersey)
INVENTOR(S)	Vladimir Egorov (Princeton, New Jersey); Heather van Raalte (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey)
ABSTRACT	Methods for assessment of pelvic floor conditions based on tactile imaging are described. The vaginal wall is deformed using a transvaginal probe equipped with tactile pressure sensors and a motion tracking sensor. The vaginal wall coordinates and pressure patterns are obtained during the examination and used to build 3-D tactile image of the vagina and to calculate elasticity modulus profiles and spacing profiles along selected lines inside 3-D tactile image. The profile values at specified locations are then compared with thresholds or profiles for normal conditions of vagina and its support structures. Methods of the invention are disclosed to be used in assessing a risk of pelvic organ prolapse development, estimating an extent of pelvic floor organ traumatic damage after childbirth and estimating an improvement after an interventional procedure.
FILED	Friday, April 08, 2011
APPL NO	13/083494
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/591
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

08188245 — Enduracidin biosynthetic gene cluster from streptomyces fungicidicus

US 08188245	Yin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) U.S. State Government State of Oregon
APPLICANT(S)
ASSIGNEE(S)	State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Xihou Yin (Corvallis, Oregon); T. Mark Zabriskie (Corvallis, Oregon)
ABSTRACT	This disclosure describes the molecular cloning of an enduracidin biosynthetic gene cluster from Streptomyces fungicidicus, and characterization of individual genes in the gene cluster and the proteins encoded thereby. An enduracidin gene cluster is located within a 116 kilobases genetic locus and includes 25 open reading frames (ORFs). An additional 23 ORFs flank the disclosed enduracidin biosynthetic gene cluster. Enduracidin analogs and a method for producing them by manipulation of the enduracidin gene cluster and specific genes therein are also disclosed.
FILED	Monday, October 01, 2007
APPL NO	12/443161
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Organic compounds 536/23.100
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 29, 2012.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2012/fedinvent-patents-20120529.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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