FedInvent™ Patents
Patent Details for Tuesday, June 12, 2012
This page was updated on Monday, March 27, 2023 at 03:22 AM GMT
Department of Defense (DOD)
| US 08196393 | Cooke et al. |
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| ASSIGNEE(S) | Delphi Technologies Holding S.arl (Troy, Michigan) |
| INVENTOR(S) | Michael Peter Cooke (Gillingham, United Kingdom); Louise A Connelly (Rainham, United Kingdom) |
| ABSTRACT | An injection device for administering a reagent into an exhaust chamber of an internal combustion engine, comprising a device inlet and a device outlet and a sub-assembly held securely within a device housing. The sub-assembly comprises (i) valve housing defining a valve seat, (ii) valve means movable outwardly from the valve housing, away from the valve seat, to permit the reagent to be delivered into the exhaust chamber through the device outlet, whereby a force is applied to the valve means due to reagent delivered to the device inlet which serves to urge the valve means away from the valve seat, and (iii) bias means for applying a biasing force to the valve means which serves to urge the valve means against the valve seat so as to prevent delivery of the reagent through the device outlet into the exhaust chamber. The device housing is a separate part from the valve housing and has a housing bore within which the valve housing is held securely so as to hold the sub-assembly securely within the device housing. |
| FILED | Thursday, July 03, 2008 |
| APPL NO | 12/217368 |
| ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Power plants 060/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08196407 | Harris et al. |
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| ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| INVENTOR(S) | Mark M. Harris (Jupiter, Florida); Wesley D. Brown (Jupiter, Florida); Angel M. Garcie (Jupiter, Florida) |
| ABSTRACT | A small gas turbine engine for use in an UAV such as a cruise missile, the gas turbine having a combustor forming a primary burn zone and a secondary burn zone, and in which fuel is injected into both the primary and the secondary burn zones by either a rotary cup injector or a plurality of fuel injector nozzles. The secondary burn zone with separate fuel injection allows for the diameter of the engine to be reduced in size but still allow for adequate power and efficiency to be reached for powering the vehicle. Air flow from the compressor is used to cool the combustor walls before being injected into the combustor, and to pass through and cool the guide nozzles and a main bearing located near the hot section of the combustor prior to being introduced into the combustor. |
| FILED | Friday, June 19, 2009 |
| APPL NO | 12/487882 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/732 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08196449 | McBrady et al. |
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| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Adam Dewey McBrady (Minneapolis, Minnesota); Fouad Nusseibeh (Champlin, Minnesota); Terry M. Marta (White Bear Lake, Minnesota); Robert Higashi (Shorewood, Minnesota) |
| ABSTRACT | A micro discharge device (MDD) capable of low voltage discharges in a variety of carrier gases for detection and/or ionization includes a sample introduction capillary having a first open end connected to a gas system and a second open end connected to a cylinder comprising a high dielectric constant material. A high voltage electrode can be placed in close proximity to the outer diameter of the cylinder and at a close linear distance to the second open end of the sample introduction capillary. A region can be formed inside the cylinder between the second end of the sample introduction capillary and the high voltage electrode wherein discharge can be located. An optical emission collector can be located through the flow manifold to a receiving location near the high voltage electrode within a region from inside the cylinder between the high voltage electrode and the manifold. |
| FILED | Thursday, October 30, 2008 |
| APPL NO | 12/262020 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08196513 | O'Rourke |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jack O'Rourke (Panama City, Florida) |
| ABSTRACT | The invention in one variation is a stand-off disrupter apparatus that includes a delivery vessel having an enlarged rounded front end with an apex and an elongate cylindrical section that in part serves to fit the apparatus onto the barrel of a shotgun. The shotgun provides propulsion. The apparatus has fins, a sighting system, a firing pin system that fires on impact, a shell loaded with shot housed in a shell chamber, and a layer of disruption medium sealed in a dish forward of the shell and set-back from the apex. The disruption medium is energized on impact by the shot from the shell and a force of the impact. The energized disruption medium can neutralize an improvised explosive device. |
| FILED | Friday, December 04, 2009 |
| APPL NO | 12/653414 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/483 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08196754 | Ho |
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| ASSIGNEE(S) | The Ohio States University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | W. S. Winston Ho (Columbus, Ohio) |
| ABSTRACT | Water permeable membranes and methods of forming water permeable membranes are provided. The water permeable membranes are comprised of a cross-linked polyamide containing at least one bifunctional additive that is hydrophilic and reactive. Additionally, in accordance with other embodiments of this invention, methods of forming water permeable membranes comprised of a cross-linked polyamide containing at least one bifunctional additive that is hydrophilic and reactive are provided. Specifically, the water permeable membranes may comprise a membrane formed from a cross-linked aromatic or aromatic/aliphatic polyamide interfacially polymerized on a porous support. The presence of the at least one hydrophilic and reactive additive improves the flux and salt retention properties of the membrane in comparison to a membrane formed without the at least one hydrophilic and reactive additive. |
| FILED | Thursday, July 17, 2008 |
| APPL NO | 12/174951 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/490 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08196844 | Kiss et al. |
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| ASSIGNEE(S) | Sturman Industries, Inc. (Woodland Park, Colorado) |
| INVENTOR(S) | Tibor Kiss (Manitou Springs, Colorado); Randall James Strauss (Colorado Springs, Colorado); James A. Peña (Encinitas, California); John Mathew Quinlan (Woodland Park, Colorado) |
| ABSTRACT | Three-way valves having reduced leakage and fuel injectors using the same. Three-way spool poppet valves are disclosed having a spool with a poppet valve thereon cooperating with a seat on the valve housing to provide a substantially leak free valve closing in one direction characteristic of a poppet valve while preserving the advantages of a spool valve. Three-way ball valves are also disclosed having substantially leak free valves closing in both directions, but further including reduced short circuit losses due to direct flow from a high pressure supply to a low pressure vent during transition of the ball from one position to the opposite position. Fuel injectors with direct needle control using the three-way valves of the present invention are also disclosed. |
| FILED | Tuesday, December 20, 2005 |
| APPL NO | 11/313861 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08196934 | Do |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Logan H. Do (Canton, Connecticut) |
| ABSTRACT | A slider seal assembly for a gas turbine engine includes a housing, a seal plate moveable relative to the housing and a retaining ring. The housing includes an outer surface, an inner surface, and a recessed opening between the outer surface and the inner surface. The seal plate is received within the recessed opening. The inner surface of the housing includes a curved portion which is curved in an outward direction toward the outer surface. |
| FILED | Wednesday, January 10, 2007 |
| APPL NO | 11/621601 |
| ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Seal for a joint or juncture 277/580 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197076 | Angel |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Matthew M. Angel (Cambridge, Massachusetts) |
| ABSTRACT | Described is a magnetic membrane mirror having a flexible membrane comprising a magnetic material and having a high reflectance. The flexible membrane is secured over a frame to enclose a volume between the frame and membrane. A transmembrane pressure is established to achieve a desired mirror shape or curvature. Curvature can be changed by modifying the transmembrane pressure by increasing or decreasing the pressure in the enclosed volume. An array of electromagnetic actuators generates individually-controlled magnetic fields to cause localized displacements of the mirror surface. The magnetic membrane mirror can be constructed with inexpensive components and can be used as a dynamic component in an adaptive optical system. |
| FILED | Tuesday, February 27, 2007 |
| APPL NO | 11/679254 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/846 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197166 | Stull et al. |
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| ASSIGNEE(S) | Alcoa Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Eric M. Stull (Lower Burrell, Pennsylvania); James T. Burg (Verona, Pennsylvania); Franklin David Silvio (Natrona Heights, Pennsylvania); Robert J. Speer (Upper Burrell, Pennsylvania) |
| ABSTRACT | A tie down assembly including a cup, a cross-shaped crossbar that is fastened removably to and positioned within a recess of the cup, and a disc-shaped plate that is fastened removably to the cup and/or the crossbar. The crossbar is fastened to the cup by a plurality of fasteners, while the plate is fastened to the cup and/or the crossbar by at least one fastener. The cup is installed within a hole formed within a first surface of a structure, and the plate is positioned against an opposite surface of the structure. When the plate is attached, a compressive load is introduced and squeezes the first and second surfaces of the structure together, such that most of the load is borne down the center of the fastener attaching the plate. |
| FILED | Monday, March 15, 2010 |
| APPL NO | 12/723995 |
| ART UNIT | 3612 — Optics |
| CURRENT CPC | Freight accommodation on freight carrier 410/106 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197184 | Chon |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Young H. Chon (Farmington, Connecticut) |
| ABSTRACT | A vane cluster has a coated metallic substrate. The cluster includes a platform and a shroud. At least first and second airfoils extend between an outer face of the platform and an inner face of the shroud. Each airfoil has a pressure side and a suction side. The pressure side of the first airfoil faces the suction side of the second airfoil. The cluster includes a cooling passageway system including one or more first feed passageways in the first airfoil and one or more second feed passageways in the second airfoil. At least a first side selected from the pressure side of the first airfoil and the suction side of the second airfoil includes a first region with a local thinning or gap in the coating. Along the first side, the cooling passageway system includes means for locally cooling said first region. |
| FILED | Wednesday, October 18, 2006 |
| APPL NO | 11/582594 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197185 | Weaver et al. |
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| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | John Alan Weaver (Indianapolis, Indiana); Tony Alan Lambert (Brownsburg, Indiana); James Sellhorn (Indianapolis, Indiana) |
| ABSTRACT | A turbine airfoil arrangement for a gas turbine engine includes an airfoil having an inlet and an exit, the inlet configured to receive a cooling gas flow operable to cool at least part of an other airfoil; and a passage disposed in the airfoil and fluidly coupled to the inlet and the exit, the exit being configured to pass at least some of the cooling gas flow to the other airfoil. |
| FILED | Monday, November 17, 2008 |
| APPL NO | 12/313063 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197196 | Davis et al. |
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| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Brian Michael Davis (West Chester, Ohio); Billy T. Wood (Cincinnati, Ohio); Gregory William Reimels (Loveland, Ohio); Louis Bruno Lorenzi (Wyoming, Ohio) |
| ABSTRACT | A bushing assembly for a turbine vane includes a bushing, housing, and a flexible conductor. The bushing includes a bore for receiving a trunnion of the vane and a first conductor extending from the bushing. The first conductor is adapted to be connected to a heater element disposed on the vane. The housing is positioned over the bushing, and the bushing is rotatable relative to the housing. The housing includes a second conductor extending from the housing for connection to an electrical power source. The flexible conductor is electrically connected between the first conductor and the second conductor, such that an electric current is transmitted from the second conductor to the first conductor to provide an electric current to the heater element. |
| FILED | Friday, November 30, 2007 |
| APPL NO | 11/948570 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197285 | Farmer |
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| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Daniel R. Farmer (Sahuarita, Arizona) |
| ABSTRACT | A conductive gasket includes a deformable contact region configured to provide compressive contact between the mounting surface of a connector (e.g., a right-angle micro-D connector) and a grounded surface of the substrate (e.g., PCB). A fastener region extends from the deformable contact region and is configured to align with a mounting region of the connector. A keep-out zone is provided adjacent to the deformable contact region and the fastener region and is configured to allow the pins of the connector to pass therethrough. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/492029 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/607.350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197409 | Foley et al. |
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| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jessica L. Foley (Seattle, Washington); Shahram Vaezy (Seattle, Washington); James W. Little (Seattle, Washington) |
| ABSTRACT | A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures. |
| FILED | Monday, February 23, 2009 |
| APPL NO | 12/390975 |
| ART UNIT | 3768 — Electrical Circuits and Systems |
| CURRENT CPC | Surgery 6/439 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197418 | Lal et al. |
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| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Darius Paduch (Red Bank, New Jersey); Ramkumar Abhishek (Ithaca, New York); Peter Schlegel (Larchmont, New York) |
| ABSTRACT | Microprobes in various designs are provided including microprobes having a bulk base and a thin probe extending from the bulk base and a Wheatstone-bridge sensor circuit for measuring strain in the thin probe, and microprobes with two thin probes extending from the bulk base with their respective integrated Wheatstone-bridges to eliminate common mode forces experienced by the two thin probes. |
| FILED | Monday, June 09, 2008 |
| APPL NO | 12/663552 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/552 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197507 | Garcia et al. |
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| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Pablo E. Garcia (Menlo Park, California); Bryan Chavez (Palo Alto, California); Jomayon Hill (San Jose, California) |
| ABSTRACT | Tissue lacerations are closed using a vacuum cup applied to the tissue surface having a tissue-abutting, optically transparent mesh surface that under vacuum conforms with the tissue surface, apposing edges of the wound, and is optionally loaded with a bandage comprising a chitosan film and a collagen backing. An eye tissue surface wound is closed without sutures by closing the wound with a bioadhesive, biocompatible sclera or cornea wound patch comprising a chitosan film and a collagen backing, wherein the backing is bonded to the film without adhesive and protects the film against dissociation when the patch is exposed to a physiological fluid, and the film adheres to the sclera sufficient to retain apposed edges of the wound. |
| FILED | Wednesday, January 14, 2009 |
| APPL NO | 12/353966 |
| ART UNIT | 3773 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery 66/215 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197578 | Hruby et al. |
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| ASSIGNEE(S) | Busek Company, Inc. (Natick, Massachusetts) |
| INVENTOR(S) | Vladimir J. Hruby (Newton, Massachusetts); Nate Demmons (Mason, New Hampshire); Tom Roy (Newton, Massachusetts); Doug Spence (Brookline, Massachusetts); Eric Ehrbar (Brookline, Massachusetts); Jurg Zwahlen (New Ipswich, New Hampshire); Charles Gasdaska (Shrewsbury, Massachusetts) |
| ABSTRACT | A liquid degasser for a space device including a gas permeable material configured for contact with a flow of liquid to be de-gassed on one side and a vacuum on the other side, and wherein the gas permeable material allows gas in the liquid to diffuse to the vacuum to remove the gas from the liquid. |
| FILED | Wednesday, July 25, 2007 |
| APPL NO | 11/881020 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation: Apparatus 096/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197619 | Nelson et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew P. Nelson (Ridgecrest, California); Nirupam J. Trivedi (Ridgecrest, California) |
| ABSTRACT | A process for making metal-organic frameworks and metal-organic frameworks having host-guest complexes of either liquid energetics, solid energetics, or solid oxidizers. |
| FILED | Wednesday, July 14, 2010 |
| APPL NO | 12/836079 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197654 | Hickenboth et al. |
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| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Charles R. Hickenboth (Cranberry Township, Pennsylvania); Walter F. Kasper (Gibsonia, Pennsylvania); James E. Poole (Gibsonia, Pennsylvania) |
| ABSTRACT | Methods for preparing an electrodepositable coating composition are provided comprising: (a) mixing a flatting agent with an electrodepositable resin; (b) combining the mixture of (a) with a pigment paste to form a flatting agent-pigment paste mixture; and (c) combining the flatting agent-pigment paste mixture of (b) with an electrodepositable resin. Methods of coating articles including electrodepositable coating compositions prepared by these methods, as well as processes for coating electroconductive substrates with compositions prepared by these methods are also provided. |
| FILED | Thursday, January 22, 2009 |
| APPL NO | 12/357699 |
| ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197722 | Marder et al. |
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| ASSIGNEE(S) | The California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Seth Marder (Pasadena, California); Joseph Perry (Pasadena, California) |
| ABSTRACT | Compositions capable of simultaneous two-photon absorption and higher order absorptivities are provided. Compounds having a donor-pi-donor or acceptor-pi-acceptor structure are of particular interest, where the donor is an electron donating group, acceptor is an electron accepting group, and pi is a pi bridge linking the donor and/or acceptor groups. The pi bridge may additionally be substituted with electron donating or withdrawing groups to alter the absorptive wavelength of the structure. Also disclosed are methods of generating an excited state of such compounds through optical stimulation with light using simultaneous absorption of photons of energies individually insufficient to achieve an excited state of the compound, but capable of doing so upon simultaneous absorption of two or more such photons. Applications employing such methods are also provided, including controlled polymerization achieved through focusing of the light source(s) used. |
| FILED | Monday, July 30, 2001 |
| APPL NO | 09/918874 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/586 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197763 | Yen et al. |
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| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Teh-Fu Yen (Altadena, California); Meng-Wei Wan (San Gabriel, California) |
| ABSTRACT | The desulfurization of fossil fuels is effected by the combination of fossil fuels with an aqueous mixture of hydroperoxide and quaternary ammonium fluoride phase transfer catalyst, the mixture then subjected to ultrasound to oxidize sulfur compounds present in the fuels. The polar oxidized species are removed via extraction. Another aspect is a portable, continuous ultrasound assisted desulfurization device having a sonoreactor for subjecting mixtures of fossil fuels to sonication to effect removal of sulfur containing compounds. |
| FILED | Thursday, September 13, 2007 |
| APPL NO | 11/854927 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197777 | Holladay et al. |
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| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jamelyn D. Holladay (Kennewick, Washington); Yong Wang (Richland, Washington); Ya-Huei Chin (Richland, Washington); Max Phelps (Richland, Washington) |
| ABSTRACT | The invention describes combustors and steam reformers and methods of combustion and steam reforming. For example, integrated combustion reactors are described in which heat from combustion is transferred to an endothermic reaction. Thermally efficient reactors and methods of alcohol steam reforming are also described. Also described is an integrated combustor/reformer containing a methanation catalyst. |
| FILED | Sunday, August 09, 2009 |
| APPL NO | 12/538140 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/629 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198039 | Shi et al. |
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| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Haibin Shi (Pittsburgh, Pennsylvania); Joanne I. Yeh (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are biosensors that comprise a biological signal source linked to a substrate by a peptide nucleic acid spacer and methods of use of the biosensor. In one embodiment, the biosensor is used to detect prostate-specific antigen. |
| FILED | Thursday, September 04, 2008 |
| APPL NO | 12/204407 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198040 | Nocker et al. |
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| ASSIGNEE(S) | Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Andreas Nocker (Utrecht, Netherlands); Anne K. Camper (Bozeman, Montana) |
| ABSTRACT | The present invention provides for a method of distinguishing dead cells from live cells using phenanthridium derivatives with a 2+ charge or higher. |
| FILED | Wednesday, February 28, 2007 |
| APPL NO | 12/280946 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/32 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198046 | Wang et al. |
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| ASSIGNEE(S) | Danisco US Inc. (Palo Alto, California) |
| INVENTOR(S) | Huaming Wang (Fremont, California); Michael Ward (San Francisco, California) |
| ABSTRACT | The invention relates to a fusion DNA construct comprising a KEX2 region comprising a KEX2 site and a KEX2 site pre-sequence immediately 5′ to the KEX2 site, a fusion polypeptide, vectors and cells comprising the fusion DNA construct, methods for producing desired proteins from filamentous fungal cells and methods for enhancing the secretion and/or cleavage of a desired protein from a cell. |
| FILED | Thursday, June 21, 2007 |
| APPL NO | 12/373121 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198079 | Clements et al. |
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| ASSIGNEE(S) | Merck Sharp and Dohme Corp. (Rahway, New Jersey) |
| INVENTOR(S) | David Edward Clements (Honolulu, Hawaii); Gordon V. L. Wang (Pearl City, Hawaii); Carolyn Weeks-Levy (Honolulu, Hawaii) |
| ABSTRACT | The present invention is directed at optimized expression vectors for the expression of native-like heterologous proteins in insect cells. Compositions of the invention are nucleotide sequences representing elements of an expression vector that when combined results in enhanced expression and secretion of heterologous proteins. The elements include sequences that define transcriptional activators, core promoters, secretion signals, and 3′ untranslated regions that are functional in insect cells. The elements contained in the optimized vectors are all synthetically derived or are modified variants of naturally occurring insect sequences. The expression vectors are useful for the expression of native-like proteins when protein encoding nucleotide sequences are operatively linked to the vectors. These vectors can be used to transform insect cells, which can then be cultured to produce the desired protein product. The expressed native-like proteins can be used in diagnostic, vaccine or other applications requiring large amounts of high quality proteins. |
| FILED | Monday, April 28, 2008 |
| APPL NO | 12/451145 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198095 | Zayhowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | John J. Zayhowski (Pepperell, Massachusetts); Mordechai Rothschild (Newton, Massachusetts); Charles M. Wynn (Groton, Massachusetts); Roderick R. Kunz (Acton, Massachusetts) |
| ABSTRACT | Methods and devices for detecting the presence of a NO forming material (e.g., a material that can form, or is, a nitrogen monoxide molecule) are disclosed based on detection of fluorescence exhibited by NO molecules in a first vibrationally excited state of a ground electronic state. Such excited NO molecules can be formed, for example, when small amounts of explosives are photodissociated. By inducing fluorescence of the material, a distinct signature of the explosive can be detected. Such techniques can be performed quickly and with a significant standoff distance, which can add to the invention's utility. In another aspection of the invention, methods and apparatus for generating electromagnetic radiation are disclosed. Such methods and apparatus can be used in conjunction with any detection method disclosed herein. |
| FILED | Friday, June 03, 2011 |
| APPL NO | 13/152622 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198096 | Swager et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); John P. Amara (Charlestown, Massachusetts) |
| ABSTRACT | The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics such as heterocycles, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer. |
| FILED | Friday, September 29, 2006 |
| APPL NO | 11/541028 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/96 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198106 | Akinwande et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Akintunde I. Akinwande (Newton, Massachusetts); Luis Fernando Velásquez-García (Boston, Massachusetts) |
| ABSTRACT | A field emitter array structure is provided. The field emitter array structure includes a plurality of vertical un-gated transistor structures formed on a semiconductor substrate. The semiconductor substrate includes a plurality of vertical pillar structures to define said un-gated transistor structures. A plurality of emitter structures are formed on said vertical un-gated transistor structures. Each of said emitter structures is positioned in a ballasting fashion on one of said vertical un-gated transistor structures so as to allow said vertical ungated transistor structure to effectively provide high dynamic resistance with large saturation currents. |
| FILED | Friday, September 19, 2008 |
| APPL NO | 12/233859 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198178 | Heikman et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Sten Heikman (Goleta, California); Yifeng Wu (Goleta, California) |
| ABSTRACT | Normally-off semiconductor devices are provided. A Group III-nitride buffer layer is provided. A Group III-nitride barrier layer is provided on the Group III-nitride buffer layer. A non-conducting spacer layer is provided on the Group III-nitride barrier layer. The Group III-nitride barrier layer and the spacer layer are etched to form a trench. The trench extends through the barrier layer and exposes a portion of the buffer layer. A dielectric layer is formed on the spacer layer and in the trench and a gate electrode is formed on the dielectric layer. Related methods of forming semiconductor devices are also provided herein. |
| FILED | Friday, July 01, 2011 |
| APPL NO | 13/175069 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198406 | Volpert et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Olga Volpert (Wilmette, Illinois); Yelena Mirochnik (Chicago, Illinois) |
| ABSTRACT | The present invention relates to methods and compositions for modulating angiogenesis. In particular, the present invention relates to Pigment Epithelial-derived Factor (PEDF) fragments for use in modulating angiogenesis and treating angiogenesis mediated disease. |
| FILED | Friday, November 07, 2008 |
| APPL NO | 12/267031 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198576 | Kennedy et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Aprolase Development Co., LLC (Wilmington, Delaware) |
| INVENTOR(S) | John Kennedy (Irvine, California); David Ludwig (Irvine, California); Christian Krutzik (Costa Mesa, California) |
| ABSTRACT | A 3-D LADAR imaging system incorporating stacked microelectronic layers is provided. A reference insert circuit inserts data into the FIFO registers at a preselected location to provide a reference point at which all FIFO shift register data may be aligned to accommodate for timing differences between layers and channels. The bin data representing the photon reflections from the various target surfaces are read out of the FIFO and processed using appropriate circuitry such as a field programmable gate array to create a synchronized 3-D point cloud for creating a 3-D target image. |
| FILED | Friday, October 10, 2008 |
| APPL NO | 12/287691 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198621 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Dahl-Young Khang (Seoul, South Korea); Yugang Sun (Naperville, Illinois); Etienne Menard (Durham, North Carolina) |
| ABSTRACT | The present invention provides stretchable, and optionally printable, semiconductors and electronic circuits capable of providing good performance when stretched, compressed, flexed or otherwise deformed. Stretchable semiconductors and electronic circuits of the present invention preferred for some applications are flexible, in addition to being stretchable, and thus are capable of significant elongation, flexing, bending or other deformation along one or more axes. Further, stretchable semiconductors and electronic circuits of the present invention may be adapted to a wide range of device configurations to provide fully flexible electronic and optoelectronic devices. |
| FILED | Tuesday, March 17, 2009 |
| APPL NO | 12/405475 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199020 | Kim |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Yoonkee Kim (Freehold, New Jersey) |
| ABSTRACT | A temperature-sensitive thermal cutoff fuse RFID tag is provided with a bimorph element and thin conductive bridges positioned on an RFID tag substrate that can react to all changes in storage temperature conditions. The bimorph element is configured and positioned so that when it bends in response to one or more predetermined temperatures, the bimorph element will break one of the conductive bridges and cause an open circuit that can be detected when the RFID tag is interrogated by a sensor. The temperature-sensitive thermal cutoff fuse RFID tag can provide high and low temperature information about numerous stored objects such as food, medicine, chemicals, batteries, explosives and munitions. Multiple temperature conductive bridge cutoff fuse RFID tag arrangements and methods for notifying the user when a required storage temperature has been reached with a passive temperature-sensitive thermal cutoff fuse RFID tag. |
| FILED | Monday, February 11, 2008 |
| APPL NO | 12/079085 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Communications: Electrical 340/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199044 | Zabetakis |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Zabetakis (Brandywine, Maryland) |
| ABSTRACT | The present invention is generally directed to an artificial dielectric composite having an electrically non-conducting substrate, an electrically non-conducting pattern on the substrate, and an electrically conducting coating on the pattern. The substrate may be a textile such as paper. The electrically non-conducting pattern may comprise palladium. A direct-write device, such as an inkjet printer, may be used to print the pattern onto the substrate. The electrically conducing coating may comprise nickel, gold, palladium, cobalt, iron, copper, or any combination thereof. Also disclosed is the related method of making the artificial dielectric composite. |
| FILED | Tuesday, March 31, 2009 |
| APPL NO | 12/414741 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199226 | McCloskey |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Scott McCloskey (Minneapolis, Minnesota) |
| ABSTRACT | Methods and systems for capturing an image of a moving subject employ a camera image sensor that captures a blurred image of a moving subject. In-capture positions of the moving object are also determined using a high frame rate camera or other motion sensing device. The PSF for controlling modulation of the light hitting the camera image is successively updated by selecting, from among a plurality of pre-computed invertible PSFs, a pre-computed invertible PSFs for each estimated motion of the moving object. Light hitting the camera image sensor is modulated in capture phase according to one or more of the updated pre-computed invertible PSFs such that the captured blurred image is invertible. The resulting invertible blurred image can be de-blurred using the selected known PSFs to provide a substantially sharp image. |
| FILED | Tuesday, September 21, 2010 |
| APPL NO | 12/886638 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Television 348/248 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199244 | Baraniuk et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard G. Baraniuk (Houston, Texas); Dror Z. Baron (Cary, North Carolina); Marco F. Duarte (Durham, North Carolina); Kevin F. Kelly (Houston, Texas); Courtney C. Lane (Ventura, California); Jason N. Laska (Houston, Texas); Dharmpal Takhar (Houston, Texas); Michael B. Wakin (Castle Rock, Colorado) |
| ABSTRACT | A new digital image/video camera that directly acquires random projections of the incident light field without first collecting the pixels/voxels. In one preferred embodiment, the camera employs a digital micromirror array to perform optical calculations of linear projections of an image onto pseudorandom binary patterns. Its hallmarks include the ability to obtain an image with only a single detection element while measuring the image/video fewer times than the number of pixels or voxels—this can significantly reduce the computation required for image/video acquisition/encoding. Since the system features a single photon detector, it can also be adapted to image at wavelengths that are currently impossible with conventional CCD and CMOS imagers. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791171 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Television 348/335 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199399 | Savage-Leuchs |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Matthias P. Savage-Leuchs (Woodinville, Washington) |
| ABSTRACT | Apparatus and method for amplifying laser signals using segments of fibers of differing core diameters and/or differing cladding diameters to suppress amplified spontaneous emission and non-linear effects such as four-wave mixing (FWM), self-phase modulation, and stimulated Brillouin and/or Raman scattering (SBS/SRS). In some embodiments, different core sizes have different sideband spacings (spacing between the desired signal and wavelength-shifted lobes). Changing core sizes and providing phase mismatches prevent buildup of non-linear effects. Some embodiments further include a bandpass filter to remove signal other than the desired signal wavelength and/or a time gate to remove signal at times other than during the desired signal pulse. Some embodiments include photonic-crystal structures to define the core for the signal and/or the inner cladding for the pump. Some embodiments include an inner glass cladding to confine the signal in the core and an outer glass cladding to confine pump light in the inner cladding. |
| FILED | Tuesday, June 14, 2011 |
| APPL NO | 13/160458 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/341.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199635 | Taylor et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Atomics (San Diego, California) |
| INVENTOR(S) | James Laurence Taylor (Sherborne, United Kingdom); Venkatagopal Racherla (San Diego, California); Jaya L. Jeyaseelan (Cupertino, California); Naiel K. Askar (San Diego, California); Michael D. Perry (Poway, California); David S. Furuno (San Diego, California) |
| ABSTRACT | A sensor network having a first command center and a first access node, comprising a wireless transceiver, coupled to the command center. The sensor network may also include a plurality of nodes individually comprising a wireless transceiver and a directional antenna, wherein each of the plurality of nodes is successively located in a downlink direction relative to the first access node, and is configured to wirelessly communicate via the directional antenna with at least one node of a first neighbor group in a first direction and at least one node of a second neighbor group in a second direction. In addition, a sensor device is individually coupled to at least one of the nodes, and is configured to provide sensor data for the first command center. |
| FILED | Monday, October 27, 2008 |
| APPL NO | 12/259213 |
| ART UNIT | 2473 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/217 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199851 | Dybdal et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Robert B. Dybdal (Palos Verdes, California); Samuel J. Curry (Redondo Beach, California); Flavio Lorenzelli (Los Angeles, California); Don J. Hinshilwood (Torrance, California) |
| ABSTRACT | Systems and methods for increasing communications bandwidth using non-orthogonal polarizations are provided herein. Under one aspect, a method of transmitting M independent signals, where M is at least 3, includes receiving the M signals from respective sources; at a transmitter polarization module, obtaining first and second linear combinations of the M signals; providing the first and second linear combinations to first and second input ports of a transmitter antenna; and transmitting with the transmitter antenna the first linear combination at a first polarization and the second linear combination at a second polarization orthogonal to the first polarization. The method may further include receiving at a receiver antenna the first linear combination at the first polarization, and the second linear combination at the second polarization; obtaining at receiver circuitry the M signals based on the received first and second linear combinations; and outputting the M signals on respective output ports. |
| FILED | Thursday, July 14, 2011 |
| APPL NO | 13/182794 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200448 | Southwell |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | William H. Southwell (Thousand Oaks, California) |
| ABSTRACT | This invention describes a means to monitor the deposition of a rugate filter such that the deposited filter will have the specified bandwidth, angular shift properties, and the correct wavelength of the reflectance peak. |
| FILED | Tuesday, February 03, 2009 |
| APPL NO | 12/322508 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/85 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200489 | Baggenstoss |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul M. Baggenstoss (Newport, Rhode Island) |
| ABSTRACT | A method for classifying data includes selecting an elemental size and features for the data that are representative of possible subclasses. Resolution widths are selected in conjunction with these features. Models associated with symbols are developed from these resolution widths and features. Data is compared with these models to give a likelihood that the model applies. The best model is determined and a signal is provided related to the symbol associated with the best model. |
| FILED | Thursday, January 29, 2009 |
| APPL NO | 12/322960 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/243 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200600 | Rosenstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Irobot Corporation (Bedford, Massachusetts) |
| INVENTOR(S) | Michael Todd Rosenstein (South Hadley, Massachusetts); Bryan Paul Adams (Jamaica Plain, Massachusetts); Nicholas George Dilip Roy (Jamaica Plain, Massachusetts) |
| ABSTRACT | A system for monitoring and predicting the condition of an electronic system comprises a component model, an inference engine based on the component model, and an action selection component that selects an action based on an output of the inference engine. |
| FILED | Thursday, March 20, 2008 |
| APPL NO | 12/052726 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200910 | Arimilli et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Robert S. Blackmore (Poughkeepsie, New York); Chulho Kim (Poughkeepsie, New York); Ramakrishnan Rajamony (Austin, Texas); Hanhong Xue (Poughkeepsie, New York) |
| ABSTRACT | A method for issuing global shared memory (GSM) operations from an originating task on a first node coupled to a network fabric of a distributed network via a host fabric interface (HFI). The originating task generates a GSM command within an effective address (EA) space. The task then places the GSM command within a send FIFO. The send FIFO is a portion of real memory having real addresses (RA) that are memory mapped to EAs of a globally executing job. The originating task maintains a local EA-to-RA mapping of only a portion of the real address space of the globally executing job. The task enables the HFI to retrieve the GSM command from the send FIFO into an HFI window allocated to the originating task. The HFI window generates a corresponding GSM packet containing GSM operations and/or data, and the HFI window issues the GSM packet to the network fabric. |
| FILED | Friday, February 01, 2008 |
| APPL NO | 12/024664 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/147 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08201110 | Gu et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Allan Gu (Alhambra, California); Avideh Zakhor (Berkeley, California); Peiran Gao (Irvine, California) |
| ABSTRACT | Optical proximity correction (OPC) is a technique used to compensate for optical distortions, process effects, or both, by modifying a pattern that is used during lithography. A reference OPC model is used to create an OPC design layout pattern based on pre-distorting a desired design layout pattern associated with an integrated circuit (IC). The OPC design layout pattern is used when the IC is produced, such that the fabricated IC ideally matches the desired design layout pattern. The present invention relates to using a regression OPC model to create estimated fragment movements of the desired design layout pattern. The estimated fragment movements are then provided as initial fragment movements to the reference OPC model, which then creates the OPC design layout pattern. The initial fragment movements provided by the regression OPC model may reduce the number of iterations needed by the reference OPC model, thereby reducing computation time. |
| FILED | Tuesday, April 14, 2009 |
| APPL NO | 12/423406 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 08197418 | Lal et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Darius Paduch (Red Bank, New Jersey); Ramkumar Abhishek (Ithaca, New York); Peter Schlegel (Larchmont, New York) |
| ABSTRACT | Microprobes in various designs are provided including microprobes having a bulk base and a thin probe extending from the bulk base and a Wheatstone-bridge sensor circuit for measuring strain in the thin probe, and microprobes with two thin probes extending from the bulk base with their respective integrated Wheatstone-bridges to eliminate common mode forces experienced by the two thin probes. |
| FILED | Monday, June 09, 2008 |
| APPL NO | 12/663552 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/552 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197435 | Prausnitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Mark R. Prausnitz (Atlanta, Georgia); Henry F. Edelhauser (Atlanta, Georgia); Samirkumar Rajnikant Patel (Atlanta, Georgia) |
| ABSTRACT | Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused fluid drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. The fluid drug formulation may flow circumferentially toward the retinochoroidal tissue, macula, and optic nerve in the posterior segment of the eye. |
| FILED | Monday, April 26, 2010 |
| APPL NO | 12/767768 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197757 | Shih et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Joseph Capobianco (Marlton, New Jersey) |
| ABSTRACT | A novel, economical electrical insulation method for the production of ultra-thin insulation layers using a solution coating method. Thin hydrophobic self-assembled bi-functional layers of less than 10 nm thick were deposited by a simple solution method and demonstrated to electrically insulate micro-/nano-devices for in-water detection applications. The insulation layer includes a hydrophobic group which repels water and permits superb insulation properties of the ultra-thin layers. The insulation layer has the additional advantages that it binds to a metal or metal oxide surface and to sensing receptors by covalent bonding using standard silane chemistry. |
| FILED | Friday, July 06, 2007 |
| APPL NO | 12/306968 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/69 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197758 | Dratz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Edward A. Dratz (Bozeman, Montana); Paul A. Grieco (Bozeman, Montana) |
| ABSTRACT | The invention relates to compositions and methods useful in the labeling and identification of proteins. The invention provides for highly soluble zwitterionic dye molecules where the dyes and associated side groups are non-titratable and maintain their net zwitterionic character over a broad pH range, for example, between pH 3 and 12. These dye molecules find utility in a variety of applications, including use in the field of proteomics. |
| FILED | Friday, June 22, 2007 |
| APPL NO | 11/767406 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197759 | Dratz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Edward A. Dratz (Bozeman, Montana); Paul A. Grieco (Bozeman, Montana) |
| ABSTRACT | The invention relates to compositions and methods useful in the labeling and identification of proteins. The invention provides for highly soluble zwitterionic dye molecules where the dyes and associated side groups are non-titratable and maintain their net zwitterionic character over a broad pH range, for example, between pH 3 and 12. These dye molecules find utility in a variety of applications, including use in the field of proteomics. |
| FILED | Monday, August 31, 2009 |
| APPL NO | 12/551114 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197807 | Brenner |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Charles M. Brenner (Lyme, New Hampshire) |
| ABSTRACT | The present invention relates to isolated nicotinamide riboside kinase (Nrk) nucleic acid sequences, vectors and cultured cells containing the same, and Nrk polypeptides encoded thereby. Methods for identifying individuals or tumors susceptible to nicotinamide riboside-related prodrug treatment and methods for treating cancer by administering an Nrk nucleic acid sequence or polypeptide in combination with a nicotinamide riboside-related prodrug are also provided. The present invention further provides screening methods for isolating a nicotinamide riboside-related prodrug and identifying a natural source of nicotinamide riboside. |
| FILED | Thursday, April 20, 2006 |
| APPL NO | 11/912400 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197811 | Abrahamson et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Julie A. Abrahamson (Harlow, United Kingdom); Connie L. Erickson-Miller (King of Prussia, Pennsylvania); Kristine Kay Kikly (Fortville, Indiana); Bruce Scott Bochner (Lutherville, Maryland); Robert Schleimer (Baltimore, Maryland); T. Esra Nutku (Baltimore, Maryland) |
| ABSTRACT | Monoclonal antibodies have been generated that bind to human sialoadhesion factor-2. These antibodies are useful as diagnostic and therapeutic reagents. |
| FILED | Friday, January 14, 2011 |
| APPL NO | 13/007450 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197819 | Srivastava et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Novartis Vaccines and Diagnostics, Inc. (Emeryville, California) |
| INVENTOR(S) | Indresh K. Srivastava (Benicia, California); Victoria Sharma (Orinda, California); Susan W. Barnett (San Francisco, California); Jeffrey Ulmer (Danville, California) |
| ABSTRACT | Provided herein are small molecule CD4 mimetics effective to bind to HIV Env proteins. A CD4 mimetic of the invention, when bound to an Env protein, is effective to induce a conformational change in the Env protein such that cyptic epitopes on the Env protein are exposed. Also provided herein are related methods of identifying and using such small molecule CD4 mimetics, for example, to elicit an immune response in a subject upon administration. |
| FILED | Wednesday, June 08, 2005 |
| APPL NO | 11/597337 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/188.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197824 | Koelle et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | David M. Koelle (Seattle, Washington); Zhi Liu (Seattle, Washington); Lawrence Corey (Mercer Island, Washington) |
| ABSTRACT | Described is a method of identifying an immunologically active antigen of a virus that attacks skin, as well as a method of enriching a population of lymphocytes for T lymphocytes that are specific to a virus that attacks skin. Also provided are HSV antigens and epitopes that are useful for the prevention and treatment of HSV infection that have been identified via the methods of the invention. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigen or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection. |
| FILED | Thursday, January 21, 2010 |
| APPL NO | 12/691309 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/231.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198021 | Ebright |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Richard H. Ebright (North Brunswick, New Jersey) |
| ABSTRACT | Target and method for inhibition of bacterial RNA polymerase disclosed are targets and methods for specific binding and inhibition of RNAP from bacterial species. |
| FILED | Friday, October 24, 2008 |
| APPL NO | 12/257801 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198029 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lasergen, Inc (Houston, Texas) |
| INVENTOR(S) | Weidong Wu (Houston, Texas); Vladislav A. Litosh (Cypress, Texas); Brian P. Stupi (Houston, Texas); Michael L. Metzker (Houston, Texas) |
| ABSTRACT | Provided are novel nucleotides, nucleoside, and their derivatives described herein, that can be used in DNA sequencing technology and other types of DNA analysis. In one embodiment, the nucleotide or nucleoside with an unprotected 3′-OH group is derivatized at the nucleobase to include a fluorescent dye attached via a linker to a non-cleavable terminating group. The non-cleavable-fluorescent group is designed to terminate DNA synthesis so that DNA oligomers can be sequenced efficiently in a parallel format. These reagents and methods will lead to more accurate identification of polymorphisms and other valuable genetic information. |
| FILED | Friday, January 07, 2011 |
| APPL NO | 12/986810 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198039 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Haibin Shi (Pittsburgh, Pennsylvania); Joanne I. Yeh (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are biosensors that comprise a biological signal source linked to a substrate by a peptide nucleic acid spacer and methods of use of the biosensor. In one embodiment, the biosensor is used to detect prostate-specific antigen. |
| FILED | Thursday, September 04, 2008 |
| APPL NO | 12/204407 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198042 | Combadiere et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, represented by the Secretary, Department of Health and Human Services (Washington, Maryland) |
| INVENTOR(S) | Christophe Combadiere (Paris, France); Philip M. Murphy (Rockville, Maryland) |
| ABSTRACT | The susceptibility of human macrophages to human immunodeficiency virus (HIV) infection depends on cell surface expression of the human CD4 molecule and CC cytokine receptor 5. CCR5 is a member of the 7-transmembrane segment superfamily of G-protein-coupled cell surface molecules. CCR5 plays an essential role in the membrane fusion step of infection by some HIV isolates. The establishment of stable, nonhuman cell lines and transgenic mammals having cells that coexpress human CD4 and CCR5 provides valuable tools for the continuing research of HIV infection. In addition, antibodies which bind to CCR5, CCR5 variants, and CCR5-binding agents, capable of blocking membrane fusion between HIV and target cells represent potential anti-HIV therapeutics for macrophage-tropic strains of HIV. |
| FILED | Friday, May 14, 2004 |
| APPL NO | 10/846185 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198048 | Zuker et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Charles S. Zuker (San Diego, California); Nicholas J. P. Ryba (Bethesda, Maryland); Gregory A. Nelson (San Diego, California); Mark A. Hoon (Kensington, Maryland); Jayaram Chandrashekar (San Diego, California); Yifeng Zhang (La Jolla, California) |
| ABSTRACT | The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors. |
| FILED | Wednesday, March 10, 2010 |
| APPL NO | 12/721463 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198059 | Harper et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeffrey Wade Harper (Wellesley, Massachusetts); Jianping Jin (Pearland, Texas) |
| ABSTRACT | A novel activating enzyme for ubiquitin, Uba6, is provided. Compositions and methods for inhibiting ubiquitin via the Uba6 pathway are provided. Methods of identifying novel inhibitors of ubiquitination are also provided. Novel RNAi molecules are also provided. |
| FILED | Tuesday, July 07, 2009 |
| APPL NO | 12/498436 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198230 | Peterson |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Blake R. Peterson (University Park, Pennsylvania) |
| ABSTRACT | The present invention relates to new synthetic receptors. More particularly, the present invention relates to the use of the synthetic receptors for delivering a protein, peptide, drug, prodrug, lipid, nucleic acid, carbohydrate or small molecule into a target cell via receptor-mediated endocytosis. According to the invention, novel synthetic mimics of cell surface receptors have been designed and methods for use of the same are disclosed. |
| FILED | Friday, January 07, 2011 |
| APPL NO | 12/930494 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198231 | Climo et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nutrition 21, Inc. (Purchase, New York) |
| INVENTOR(S) | Michael Climo (Richmond, Virginia); Ellen Murphy (Bronx, New York); Gordon Archer (Richmond, Virginia) |
| ABSTRACT | Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against staphylococci due to antibiotic activity mediated by cell-wall activity is effective against staphylococcal infection, even staphylococci that may be resistant to one or other of lysostaphin or the cell-wall active antibiotic. Co-administration simultaneously suppresses the generation of antibiotic-resistant mutant strains. Effective cell-wall active antibiotics include β-lactams and glycopeptides. |
| FILED | Friday, June 02, 2006 |
| APPL NO | 11/445289 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198234 | Laskowitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cognosci, Incorporated (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Daniel T. Laskowitz (Chapel Hill, North Carolina); William D. Matthew (Durham, North Carolina); Michael McMillian (Rareton, New Jersey) |
| ABSTRACT | Methods of suppressing the activation of microglial cells in the Central Nervous System (CNS), methods of ameliorating or treating the neurological effects of cerebral ischemia or cerebral inflammation, and methods of combating specific diseases that affect the CNS by administering a compound that binds to microglial receptors and prevents or reduces microglial activation are described. Also described are methods of screening compounds for the ability to suppress or reduce microglial activation. |
| FILED | Thursday, May 13, 2010 |
| APPL NO | 12/779725 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198236 | Bu |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Guojun Bu (Chesterfield, Missouri) |
| ABSTRACT | Oligopeptides which can be used to treat cancer are disclosed. Further disclosed are methods of treating cancer, including breast cancer, skin cancer, prostate cancer and multiple myeloma (MM). These methods include administration of a polypeptide encoded by the Mesd gene, or an oligopeptide comprising a contiguous subsequence of a Mesd polypeptide. |
| FILED | Wednesday, April 30, 2008 |
| APPL NO | 12/598240 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198241 | Dewhirst et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mark W. Dewhirst (Durham, North Carolina); Jonathan S. Stamler (Chapel Hill, North Carolina); Timothy J. McMahon (Durham, North Carolina); Pierre Sonveaux (Ottignies-Louvain-la-Neuve, Belgium) |
| ABSTRACT | The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders associated with hypoxia in subjects, methods for increasing sensitivity of tumors to radiation and/or chemotherapy treatments, methods for delaying tumor growth in subjects, and methods for inhibiting tumor blood vessel growth in subjects. In some embodiments, the presently disclosed methods involve administering to subjects in need thereof a first composition selected from the group consisting of a nitrosylated hemoglobin and an agent that induces nitrosylation of endogenous hemoglobin in the subject and a second composition comprising a hyperoxic gas. In some embodiments, the presently disclosed methods also include treating a tumor with radiation therapy, chemotherapy, photodynamic therapy, immunotherapy, or combinations thereof. Also provided are inhalable gases that can be employed in the presently disclosed methods. |
| FILED | Friday, July 30, 2010 |
| APPL NO | 12/847330 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198244 | Hearing et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Vincent Hearing (Leesburg, Virginia); Yuji Yamaguchi (Osaka, Japan); Thierry Passeron (Nice, France) |
| ABSTRACT | The present disclosure is generally related to methods of inducing non-palmoplantar skin to develop a palmoplantar phenotype, for example, methods for increasing skin thickness, decreasing skin pigmentation, and/or decreasing hair growth. In particular, disclosed herein are methods of using topical administration of DKK1 to increase skin thickness, decrease skin pigmentation, or reduce hair growth. Also disclosed are topical DKK1 compositions for inducing non-palmoplantar skin to develop a palmoplantar phenotype. |
| FILED | Friday, December 07, 2007 |
| APPL NO | 12/518052 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/18.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198252 | Evans et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | B. Mark Evans (Galveston, Texas); Piotr G. Rychahou (Galveston, Texas) |
| ABSTRACT | The present invention provides polynucleotides, compositions including polynucleotides, and the uses thereof for treating cancer in a subject. The polynucleotides silence the expression of coding regions that encode polypeptides such as p85α, p110α, and Akt2. The cancers treatable using the methods described herein include colorectal cancer, breast cancer, lung cancer, and metastases thereof. |
| FILED | Friday, May 18, 2007 |
| APPL NO | 12/301387 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198254 | Hu et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhi Hu (El Cerrito, California); Wen-Lin Kuo (San Ramon, California); Richard M. Neve (San Mateo, California); Joe W. Gray (San Francisco, California) |
| ABSTRACT | Amplification of the ANXA9 gene in human chromosomal region 1q21 in epithelial cancers indicates a likelihood of both in vivo drug resistance and metastasis, and serves as a biomarker indicating these aspects of the disease. ANXA9 can also serve as a therapeutic target. Interfering RNAs (iRNAs) (such as siRNA and miRNA) and shRNA adapted to inhibit ANXA9 expression, when formulated in a therapeutic composition, and delivered to cells of the tumor, function to treat the epithelial cancer. |
| FILED | Thursday, March 26, 2009 |
| APPL NO | 12/412304 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198265 | Munn et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Medical College of Georgia Research Institute Inc. (Augusta, Georgia) |
| INVENTOR(S) | David Munn (Augusta, Georgia); Andrew Mellor (Augusta, Georgia) |
| ABSTRACT | A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment. Studies demonstrate that expression of IDO can serve as a marker of suppression of T cell activation, and may play a significant role in allogeneic pregnancy and therefore other types of transplantation, and that inhibitors of IDO can be used to activate T cells and therefore enhance T cell activation when the T cells are suppressed by pregnancy, malignancy or a virus such as HIV. Inhibiting tryptophan degradation (and thereby increasing tryptophan concentration while decreasing tryptophan metabolite concentration), or supplementing tryptophan concentration, can therefore be used in addition to, or in place of, inhibitors of IDO. Similarly, increasing tryptophan degradation (thereby, decreasing tryptophan concentration and increasing tryptophan metabolite concentration), for example, by increasing IDO concentration or IDO activity, can suppress T cells. Although described particularly with reference to IDO regulation, one can instead manipulate local tryptophan concentrations, and/or modulate the activity of the high affinity tryptophan transporter, and/or administer other tryptophan degrading enzymes. Regulation can be further manipulated using cytokines such as macrophage colony stimulating factor, interferon gamma, alone or in combination with antigen or other cytokines. |
| FILED | Tuesday, November 21, 2006 |
| APPL NO | 11/603291 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198309 | Charvat et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ChemoCentryx, Inc. (Mountain View, California) |
| INVENTOR(S) | Trevor T. Charvat (San Jose, California); Cheng Hu (Menlo Park, California); Anita Melikian (San Francisco, California); Aaron Novack (San Jose, California); Andrew M. K. Pennell (San Francisco, California); Edward J. Sullivan (San Jose, California); William D. Thomas (San Jose, California); Solomon Ungashe (Fremont, California); Penglie Zhang (Foster City, California); Jay Powers (Pacifica, California); Sreenivas Punna (Sunnyvale, California) |
| ABSTRACT | Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists. |
| FILED | Thursday, July 08, 2010 |
| APPL NO | 12/832374 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/359 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198328 | Brooks et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Peter C. Brooks (Carmel, New York); Danielle Morais (Bedford Hills, New York); Leonard Liebes (New York, New York); Dorothy Rodriguez (Rowland Hts., California) |
| ABSTRACT | The present invention provides a method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy. Also provided are methods of screening for benzoic derivatives based on their ability to inhibit the enzyme tyrosinase or to bind to and activate PXR/SXR xenobiotic receptors. |
| FILED | Wednesday, January 19, 2005 |
| APPL NO | 11/040611 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/567 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08198334 — Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
| US 08198334 | McGrath |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Pathologica LLC (Burlingame, California) |
| INVENTOR(S) | Michael McGrath (Burlingame, California) |
| ABSTRACT | Methods for modulating macrophage proliferation in an individual afflicted with or at risk for an ocular disease such as ARMD are provided. The methods employ a polyamine analog, or salt or protected derivative thereof. Macrophage proliferation has been implicated in a number of serious disorders, including ARMD. The invention also provides methods for aiding diagnosis and monitoring therapy of an ocular disease such as ARMD. |
| FILED | Tuesday, February 22, 2005 |
| APPL NO | 11/064781 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/674 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198402 | Tarasova et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Nadya Tarasova (Frederick, Maryland); Michael Dean (Frederick, Maryland); Hong Lou (Frederick, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified polypeptide or peptidomimetic comprising an amino acid sequence of a portion of a Smoothened (SMO) protein, wherein the portion comprises an amino acid sequence of any of the intracellular loops of the SMO protein, a functional fragment thereof, or a functional variant of either the portion or the functional fragment, wherein the functional fragment comprises at least 7 contiguous amino acids of the intracellular loops, and wherein the functional fragment or functional variant inhibits proliferation of a diseased cell, or a fatty acid derivative thereof. Related conjugates, nucleic acids, recombinant expression vectors, host cells, and pharmaceutical compositions are further provided. Methods of inhibiting proliferation of a diseased cell, treating or preventing cancer, treating a neoplasm or psoriasis, and inhibiting the expression of genes involved in the Hedgehog signaling pathway, thereby inhibiting the Hedgehog signaling pathway, are furthermore provided by the invention. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 12/513091 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198405 | Walensky et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Loren D. Walensky (Chestnut Hill, Massachusetts); Stanley J. Korsmeyer (Weston, Massachusetts); Susan Korsmeyer, legal representative (Weston, Massachusetts); Gregory Verdine (Newton, Massachusetts) |
| ABSTRACT | Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death. |
| FILED | Wednesday, July 30, 2008 |
| APPL NO | 12/182673 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198406 | Volpert et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Olga Volpert (Wilmette, Illinois); Yelena Mirochnik (Chicago, Illinois) |
| ABSTRACT | The present invention relates to methods and compositions for modulating angiogenesis. In particular, the present invention relates to Pigment Epithelial-derived Factor (PEDF) fragments for use in modulating angiogenesis and treating angiogenesis mediated disease. |
| FILED | Friday, November 07, 2008 |
| APPL NO | 12/267031 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198411 | Adams et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gregory P. Adams (Hatboro, Pennsylvania); Heidi H. Simmons (Willow Grove, Pennsylvania); Qing-an Yuan (Philadelphia, Pennsylvania); Wayne Marasco (Wellesley, Massachusetts); Smita Mehta (Spartanburg, South Carolina) |
| ABSTRACT | Compositions and methods for detecting and treating cancers expressing Mullerian inhibiting substance Type II receptor (MISIIR) are provided. |
| FILED | Monday, July 12, 2010 |
| APPL NO | 12/834338 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198419 | Thorson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Jon Thorson (Middleton, Wisconsin) |
| ABSTRACT | The present invention provides glycorandomaized structures and combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. The glycosyltransferase may be one that is associated with or involved in production of natural secondary metabolites, or one which is putatively associated with or involved in production of natural secondary metabolites. The glycosyltransferase may show significant flexibility with respect to its NDP-sugar donors and/or its aglycons. NDP-sugar donors may be commercially available, or may be produced by utilizing mutant or wild type nucleotidyltransferases significant flexibility with respect to their substrates. |
| FILED | Tuesday, February 01, 2011 |
| APPL NO | 13/018811 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198424 | Mizel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Steven B. Mizel (Lewisville, North Carolina); Anna Nichole Honko (Fort Mills, South Carolina) |
| ABSTRACT | The invention provides a fusion protein comprising a flagellin adjuvant and a Yersinia pestis antigen. Also provided are compositions comprising a flagellin adjuvant and a Yersinia pestis antigen. The invention also discloses methods of making a fusion protein comprising a flagellin adjuvant and a Yersinia pestis antigen. The invention further provides pharmaceutical formulations and methods for inducing an immune response against Yersinia pestis. |
| FILED | Thursday, July 15, 2010 |
| APPL NO | 12/837223 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198425 | Wang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York, University at Albany (Albany, New York) |
| INVENTOR(S) | Sho-Ya Wang (Voorheesville, New York) |
| ABSTRACT | Isolated nucleic acid comprising a nucleotide sequence that codes for a mutant mammalian Nav1 protein are disclosed. |
| FILED | Tuesday, April 06, 2010 |
| APPL NO | 12/755317 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198432 | Pandey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York); The Research Foundation of SUNY (Amherst, New York) |
| INVENTOR(S) | Ravindra K. Pandey (Williamsville, New York); Munawwar Sajjad (Clarence Center, New York); Suresh Pandey (Chelmsford, Massachusetts); Amy Gryshuk (Livermore, California); Allan Oseroff (Buffalo, New York); Stephanie Pincus, legal representative (Buffalo, New York); Hani A. Nabi (Clarence, New York) |
| ABSTRACT | This invention describes a first report on the synthesis of certain 124I-labelled photosensitizers related to chlorines and bacteriochlorins with long wavelength absorption in the range of 660-800 nm. In preliminary studies, these compounds show a great potential for tumor detection by positron emission tomography (PET) and treatment by photodynamic therapy (PDT). The development of tumor imaging or improved photodynamic therapy agent(s) itself represent an important step, but a dual function agent (PET imaging and PDT) provides the potential for diagnostic body scan followed by targeted therapy. |
| FILED | Wednesday, August 05, 2009 |
| APPL NO | 12/462535 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198604 | Mertz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Jerome Mertz (Boston, Massachusetts) |
| ABSTRACT | A system for providing enhanced background rejection in thick tissue contains an aberrating element for introducing controllable extraneous spatial aberrations in an excitation beam path; at least one mirror capable of directing received laser pulses to the aberrating element; an objective; a beam scanner imaged onto a back aperture of the objective so that the beam scanner steers beam focus within the thick tissue; and a detector for recording signals produced by the tissue. An associated method comprises the steps of acquiring two-photon excited fluorescence of thick tissue without extraneous aberrations; introducing an extraneous aberration pattern in an excitation beam path; acquiring two-photon excited fluorescence of the thick tissue having the introduced extraneous aberration pattern; and subtracting the two-photon excited fluorescence with extraneous aberrations from the acquired standard two-photon excited fluorescence of the thick tissue without extraneous aberrations. |
| FILED | Monday, September 29, 2008 |
| APPL NO | 12/240074 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/458.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198891 | Sacolick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Laura I. Sacolick (Munich, Germany); Mika W. Vogel (Landshut, Germany); Florian Wiesinger (Freising, Germany); Ileana Hancu (Clifton Park, New York) |
| ABSTRACT | An apparatus, system, and method including a magnetic resonance imaging (MRI) apparatus includes a magnetic resonance imaging (MRI) system having a plurality of gradient coils positioned about a bore of a magnet, and an RF transceiver system and an RF switch controlled by a pulse module to transmit RF signals to an RF coil assembly to acquire MR images, and a computer. The computer is programmed to apply a first off-resonant radio frequency (RF) pulse at a first frequency different than the resonant frequency to a plurality of nuclei excited at a resonant frequency, acquire a first signal from the plurality of nuclei after application of the first off-resonant RF pulse, determine a phase shift from the first signal based on the first off-resonant RF pulse, determine a B1 field based on the phase shift, and store the B1 field on a computer readable storage medium. |
| FILED | Monday, June 15, 2009 |
| APPL NO | 12/484457 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200311 | Spincemaille et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Pascal Spincemaille (New York, New York); Yi Wang (New York, New York); Martin R. Prince (New York, New York) |
| ABSTRACT | Described is a robust electrocardiogram (ECG) ordering technique of k-space for breath hold contrast enhanced magnetic resonance angiography (CE-MRA) that acquires the central part of k-space in a motion-free portion of diastole and fills in from the periphery of k-space at all other times. To make maximal use of the contrast enhancement, data is acquired continuously even when the ECG signal is lost. The ECG signal is monitored in real time. The ECG ordering technique allows a flexible acquisition matrix and is robust against ECG signal imperfections. The ECG ordering technique allows thoracic and pulmonary magnetic resonance angiography with a higher resolution when compared to the conventional gated sequence. |
| FILED | Friday, April 20, 2007 |
| APPL NO | 11/737812 |
| ART UNIT | 3737 — Selective Visual Display Systems |
| CURRENT CPC | Surgery 6/413 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200312 | Degani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Yeda Research and Development Co. Ltd. (Rehovot, Israel) |
| INVENTOR(S) | Hadassa Degani (Rehovot, Israel); Yaron Hassid (Rehovot, Israel) |
| ABSTRACT | A method, apparatus and a computer readable medium containing executable instructions for monitoring a system pressure within a mammal, human or animal, via a tracer/contrast agent, in space in time for determining non-invasively actual interstitial fluid pressure and/or concentration of the tracer/contrast agent. Further, an imaging method, an apparatus and a product for non-invasive mapping of actual interstitial fluid pressure and/or a tracer/contrast agent concentration for assessing drug delivery and resistance to therapy of a tumor or organ within a mammal, to suppress or reduce pressure in a tumor or organ and to control the delivery of drugs to a tumor or organ. |
| FILED | Thursday, September 06, 2007 |
| APPL NO | 12/440066 |
| ART UNIT | 3768 — Selective Visual Display Systems |
| CURRENT CPC | Surgery 6/420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200338 | Grennberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert Jay Grennberg (Los Angeles, California); Mark S. Humayun (Glendale, California) |
| ABSTRACT | Present invention is a method of improving circadian rhythms in blind people by stimulation the visual neural system. Ideally a retinal prosthesis of the type used to restore vision can be used to restore normal circadian rhythms. Additionally, brightness on the prosthesis can be increased in the morning and decreased in the evening to stimulate normal Circadian rhythms. Alternatively, if a retinal prosthesis is not preferable, the retina can be stimulated externally, during the day and not at night. While such eternal stimulation can not produced artificial vision, it can stimulate normal circadian rhythms. |
| FILED | Friday, January 13, 2006 |
| APPL NO | 11/331625 |
| ART UNIT | 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE43472 | Das et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey); University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Kiron M. Das (Basking Ridge, New Jersey); Jim Jung-Ching Lin (Iowa City, Iowa) |
| ABSTRACT | A novel isoform of tropomyosin is disclosed. The isoform is closely related to epithelial human tropomyosin (hTM) and more particularly to hTM5 except the last coding exon. The novel isoform, is called TC22. Northern blot analysis with TC22-specific probe revealed that normal culture cell lines and normal epithelial tissues expressed very little, if at all, TC22 message, whereas their transformed counterparts and tumor tissues including dysfunction of the alimentary canal, significantly increased the expression of TC22. Assays directed at determining the level of TC22 are useful in diagnostics and therapeutics of dysfunction of the alimentary canal. Specific antibodies and mimics for TC22 are also disclosed for use in diagnostics and therapeutics of dysfunction of the alimentary canal. |
| FILED | Friday, October 23, 2009 |
| APPL NO | 12/604840 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08196658 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | David Scott Miller (Katy, Texas); Uzo Philip Uwechue (Houston, Texas) |
| ABSTRACT | A method for treating a hydrocarbon containing formation includes providing heat input to a first section of the formation from one or more heat sources located in the first section. Fluids are produced from the first section through a production well located at or near the center of the first section. The heat sources are configured such that the average heat input per volume of formation in the first section increases with distance from the production well. |
| FILED | Monday, October 13, 2008 |
| APPL NO | 12/250364 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Wells 166/272.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197218 | Tangler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | James L. Tangler (Boulder, Colorado); Dan L. Somers (Port Matilda, Pennsylvania) |
| ABSTRACT | Thick airfoil families with desirable aerodynamic performance with minimal airfoil induced noise. The airfoil families are suitable for a variety of wind turbine designs and are particularly well-suited for use with horizontal axis wind turbines (HAWTs) with constant or variable speed using pitch and/or stall control. In exemplary embodiments, a first family of three thick airfoils is provided for use with small wind turbines and second family of three thick airfoils is provided for use with very large machines, e.g., an airfoil defined for each of three blade radial stations or blade portions defined along the length of a blade. Each of the families is designed to provide a high maximum lift coefficient or high lift, to exhibit docile stalls, to be relatively insensitive to roughness, and to achieve a low profile drag. |
| FILED | Thursday, November 08, 2007 |
| APPL NO | 11/937183 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/238 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197574 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Iver E. Anderson (Ames, Iowa); Robert L. Terpstra (Ames, Iowa) |
| ABSTRACT | A method of making dispersion-strengthened alloy particles involves melting an alloy having a corrosion and/or oxidation resistance-imparting alloying element, a dispersoid-forming element, and a matrix metal wherein the dispersoid-forming element exhibits a greater tendency to react with a reactive species acquired from an atomizing gas than does the alloying element. The melted alloy is atomized with the atomizing gas including the reactive species to form atomized particles so that the reactive species is (a) dissolved in solid solution to a depth below the surface of atomized particles and/or (b) reacted with the dispersoid-forming element to form dispersoids in the atomized particles to a depth below the surface of said atomized particles. The atomized alloy particles are solidified as solidified alloy particles or as a solidified deposit of alloy particles. Bodies made from the dispersion strengthened alloy particles, deposit thereof, exhibit enhanced fatigue and creep resistance and reduced wear as well as enhanced corrosion and/or oxidation resistance at high temperatures by virtue of the presence of the corrosion and/or oxidation resistance imparting alloying element in solid solution in the particle alloy matrix. |
| FILED | Thursday, February 25, 2010 |
| APPL NO | 12/660354 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/232 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197887 | Burckel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | David Bruce Burckel (Albuquerque, New Mexico) |
| ABSTRACT | A fabrication method is capable of creating canonical metamaterial structures arrayed in a three-dimensional geometry. The method uses a membrane suspended over a cavity with predefined pattern as a directional evaporation mask. Metallic and/or dielectric material can be evaporated at high vacuum through the patterned membrane to deposit resonator structures on the interior walls of the cavity, thereby providing a unit cell of micron-scale dimension. The method can produce volumetric metamaterial structures comprising layers of such unit cells of resonator structures. |
| FILED | Thursday, July 30, 2009 |
| APPL NO | 12/512082 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/97.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197955 | Tamaki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Ryo Tamaki (Santa Clarita, California); Steven Thomas Rice (Scotia, New York); Gary William Yeager (Rexford, New York) |
| ABSTRACT | Disclosed herein is a method of forming an electrolyte membrane comprising forming a mixture; the mixture comprising a polyhydroxy compound, an aromatic polyhalide compound and an alkali metal hydroxide; disposing the mixture on a porous substrate; reacting the mixture to form a proton conductor; and crosslinking the proton conductor to form a cross-linked proton-conducting network. Disclosed herein too is an article comprising a porous substrate; and a crosslinked proton conductor disposed on the porous substrate. |
| FILED | Tuesday, September 02, 2008 |
| APPL NO | 12/202832 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197982 | Haltiner, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies, Inc. (Troy, Michigan) |
| INVENTOR(S) | Karl J. Haltiner, Jr. (Fairport, New York); Arun Venkiteswaran (Karnataka, India) |
| ABSTRACT | A fuel cell stack is provided with a plurality of fuel cell cassettes where each fuel cell cassette has a fuel cell with an anode and cathode. The fuel cell stack includes an anode supply chimney for supplying fuel to the anode of each fuel cell cassette, an anode return chimney for removing anode exhaust from the anode of each fuel cell cassette, a cathode supply chimney for supplying oxidant to the cathode of each fuel cell cassette, and a cathode return chimney for removing cathode exhaust from the cathode of each fuel cell cassette. A first fuel cell cassette includes a flow control member disposed between the anode supply chimney and the anode return chimney or between the cathode supply chimney and the cathode return chimney such that the flow control member provides a flow restriction different from at least one other fuel cell cassettes. |
| FILED | Tuesday, November 15, 2011 |
| APPL NO | 13/296580 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/471 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198044 | Ryu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Youngha Ryu (San Diego, California); Peter G. Schultz (La Jolla, California) |
| ABSTRACT | The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions. |
| FILED | Wednesday, March 07, 2007 |
| APPL NO | 12/224773 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198075 | Greenbaum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Elias Greenbaum (Knoxville, Tennessee); Miguel Rodriguez, Jr. (Oak Ridge, Tennessee); Jie Jayne Wu (Knoxville, Tennessee); Hairong Qi (Knoxville, Tennessee) |
| ABSTRACT | A water quality analyzer for real-time detection according to the invention comprises a biased AC electro-osmosis (ACEO) cell for receiving a fluid to be analyzed having a plurality photosynthetic organisms therein, and concentrating the plurality photosynthetic organisms into at least one concentrated region. A photodetector is provided for obtaining a measured photosynthetic activity of the plurality of photosynthetic organisms in the concentrated region, wherein chemical, biological or radiological agents reduce a nominal photosynthetic activity of the photosynthetic organisms. An electronics package analyzes the measured photosynthetic activity to indicate a presence of the chemical, biological or radiological agents in the fluid. |
| FILED | Thursday, November 10, 2005 |
| APPL NO | 11/271643 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/292.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198254 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhi Hu (El Cerrito, California); Wen-Lin Kuo (San Ramon, California); Richard M. Neve (San Mateo, California); Joe W. Gray (San Francisco, California) |
| ABSTRACT | Amplification of the ANXA9 gene in human chromosomal region 1q21 in epithelial cancers indicates a likelihood of both in vivo drug resistance and metastasis, and serves as a biomarker indicating these aspects of the disease. ANXA9 can also serve as a therapeutic target. Interfering RNAs (iRNAs) (such as siRNA and miRNA) and shRNA adapted to inhibit ANXA9 expression, when formulated in a therapeutic composition, and delivered to cells of the tumor, function to treat the epithelial cancer. |
| FILED | Thursday, March 26, 2009 |
| APPL NO | 12/412304 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198336 | Petruska et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Melissa A. Petruska (Los Alamos, New Mexico); Victor L. Klimov (Los Alamos, New Mexico) |
| ABSTRACT | The present invention is directed to solid composites including colloidal nanocrystals within a sol-gel host or matrix and to processes of forming such solid composites. The present invention is further directed to alcohol soluble colloidal nanocrystals useful in formation of sol-gel based solid composites |
| FILED | Tuesday, June 05, 2007 |
| APPL NO | 11/810508 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Colloid systems and wetting agents; subcombinations thereof; processes of 516/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198484 | Martinez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Rodolfo A. Martinez (Santa Fe, New Mexico); Clifford J. Unkefer (Los Alamos, New Mexico); Marc A. Alvarez (Santa Fe, New Mexico) |
| ABSTRACT | The present invention is directed to the labeled compounds, wherein C* is each either 13C and 12C where at least one C* is 13C, each hydrogen of the methylene group is hydrogen or deuterium, the methyl group includes either zero or three deuterium atoms, Q is sulfide, sulfinyl, or sulfone, Z is an aryl group such as 1-naphthyl, substituted 1-naphthyl, 2-naphthyl, substituted 2-naphthyl, or a phenyl group wherein R1, R2, R3, R4 and R5 are each independently either hydrogen, a C1-C4 lower alkyl, a halogen, and an amino group such as NH2, NHR and NRR′ where R and R′ are each independently either a C1-C4 lower alkyl, a phenyl, and an alkoxy group, and the methyl group can include either zero or three deuterium atoms. The present invention is also directed to the labeled compounds |
| FILED | Tuesday, July 22, 2008 |
| APPL NO | 12/220234 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/199 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198486 | Cortright |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virent, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Randy D. Cortright (Madison, Wisconsin) |
| ABSTRACT | Disclosed are methods for generating propylene glycol, ethylene glycol and other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols from biomass using hydrogen produced from the biomass. The methods involve reacting a portion of an aqueous stream of a biomass feedstock solution over a catalyst under aqueous phase reforming conditions to produce hydrogen, and then reacting the hydrogen and the aqueous feedstock solution over a catalyst to produce propylene glycol, ethylene glycol and the other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols. The disclosed methods can be run at lower temperatures and pressures, and allows for the production of oxygenated hydrocarbons without the need for hydrogen from an external source. |
| FILED | Tuesday, June 28, 2011 |
| APPL NO | 13/170757 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 568/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198621 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Dahl-Young Khang (Seoul, South Korea); Yugang Sun (Naperville, Illinois); Etienne Menard (Durham, North Carolina) |
| ABSTRACT | The present invention provides stretchable, and optionally printable, semiconductors and electronic circuits capable of providing good performance when stretched, compressed, flexed or otherwise deformed. Stretchable semiconductors and electronic circuits of the present invention preferred for some applications are flexible, in addition to being stretchable, and thus are capable of significant elongation, flexing, bending or other deformation along one or more axes. Further, stretchable semiconductors and electronic circuits of the present invention may be adapted to a wide range of device configurations to provide fully flexible electronic and optoelectronic devices. |
| FILED | Tuesday, March 17, 2009 |
| APPL NO | 12/405475 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199787 | Deri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Robert J. Deri (Pleasanton, California); Jack Kotovsky (Oakland, California); Christopher M. Spadaccini (Oakland, California) |
| ABSTRACT | A laser diode package assembly includes a reservoir filled with a fusible metal in close proximity to a laser diode. The fusible metal absorbs heat from the laser diode and undergoes a phase change from solid to liquid during the operation of the laser. The metal absorbs heat during the phase transition. Once the laser diode is turned off, the liquid metal cools off and resolidifies. The reservoir is designed such that that the liquid metal does not leave the reservoir even when in liquid state. The laser diode assembly further includes a lid with one or more fin structures that extend into the reservoir and are in contact with the metal in the reservoir. |
| FILED | Thursday, August 04, 2011 |
| APPL NO | 13/198393 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08201099 | Osbourn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Gordon Cecil Osbourn (Albuquerque, New Mexico); Ann Marie Bouchard (Albuquerque, New Mexico) |
| ABSTRACT | An adaptable computing environment is implemented with software entities termed “s-machines”, which self-assemble into hierarchical data structures capable of rendering and interacting with the computing environment. A hierarchical data structure includes a first hierarchical s-machine bound to a second hierarchical s-machine. The first hierarchical s-machine is associated with a first layer of a rendering region on a display screen and the second hierarchical s-machine is associated with a second layer of the rendering region overlaying at least a portion of the first layer. A screen element s-machine is linked to the first hierarchical s-machine. The screen element s-machine manages data associated with a screen element rendered to the display screen within the rendering region at the first layer. |
| FILED | Tuesday, September 26, 2006 |
| APPL NO | 11/527002 |
| ART UNIT | 2175 — Graphical User Interface and Document Processing |
| CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/778 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08197539 | Nasiatka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Patrick J. Nasiatka (Westminster, California); Michelle C. Hauer (Hawthorne, California); Noelle R. B. Stiles (Orange, California); Armand R. Tanguay, Jr. (Yorba Linda, California); Mark S. Humayun (Glendale, California) |
| ABSTRACT | An intraocular camera for retinal prostheses may include an optical imaging system comprising a set of optical elements for forming an image of the external world on an image sensor array, wherein the optical elements and the image sensor array may be enclosed in an implantable biocompatible housing that may employ haptic elements for stabilization within the eye. The set of optical elements may be designed to have a short focal length and to provide adequate resolution images that can be transformed into a set of stimulation signals applied to a pixellated microstimulator array. Transmission of the signals from the intraocular camera to a microstimulator driver circuit may be accomplished either by a wired or wireless communication device. Power and control signals may be provided to the intraocular camera by a wired or wireless communication device, or optically by means of ambient illumination or an optical beam. |
| FILED | Friday, May 04, 2007 |
| APPL NO | 11/744714 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Prosthesis 623/4.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197722 | Marder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Seth Marder (Pasadena, California); Joseph Perry (Pasadena, California) |
| ABSTRACT | Compositions capable of simultaneous two-photon absorption and higher order absorptivities are provided. Compounds having a donor-pi-donor or acceptor-pi-acceptor structure are of particular interest, where the donor is an electron donating group, acceptor is an electron accepting group, and pi is a pi bridge linking the donor and/or acceptor groups. The pi bridge may additionally be substituted with electron donating or withdrawing groups to alter the absorptive wavelength of the structure. Also disclosed are methods of generating an excited state of such compounds through optical stimulation with light using simultaneous absorption of photons of energies individually insufficient to achieve an excited state of the compound, but capable of doing so upon simultaneous absorption of two or more such photons. Applications employing such methods are also provided, including controlled polymerization achieved through focusing of the light source(s) used. |
| FILED | Monday, July 30, 2001 |
| APPL NO | 09/918874 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/586 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197758 | Dratz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Edward A. Dratz (Bozeman, Montana); Paul A. Grieco (Bozeman, Montana) |
| ABSTRACT | The invention relates to compositions and methods useful in the labeling and identification of proteins. The invention provides for highly soluble zwitterionic dye molecules where the dyes and associated side groups are non-titratable and maintain their net zwitterionic character over a broad pH range, for example, between pH 3 and 12. These dye molecules find utility in a variety of applications, including use in the field of proteomics. |
| FILED | Friday, June 22, 2007 |
| APPL NO | 11/767406 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197759 | Dratz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Edward A. Dratz (Bozeman, Montana); Paul A. Grieco (Bozeman, Montana) |
| ABSTRACT | The invention relates to compositions and methods useful in the labeling and identification of proteins. The invention provides for highly soluble zwitterionic dye molecules where the dyes and associated side groups are non-titratable and maintain their net zwitterionic character over a broad pH range, for example, between pH 3 and 12. These dye molecules find utility in a variety of applications, including use in the field of proteomics. |
| FILED | Monday, August 31, 2009 |
| APPL NO | 12/551114 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198099 | Raymo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Miami (Miami, Florida) |
| INVENTOR(S) | Francisco M. Raymo (Coral Gables, Florida); Massimilliano Tomasulo (Miami, Florida); Ibrahim Yildiz (Miami, Florida) |
| ABSTRACT | Semiconductor quantum dots are becoming valuable analytical tools for use in biomedical applications. Indeed, their unique properties offer the opportunity to design luminescent probes for imaging and sensing with unprecedented performance. In this context, we have identified operating principles to transduce supramolecular association of complementary receptor-ligand binding pairs into enhancement or suppression in the luminescence of sensitive quantum dots. Thus, complementary receptor-ligand binding pairs can be identified with luminescence measurements relying on our design logic. In fact, we have demonstrated with a representative example that our protocol can be adapted to signal receptor-ligand binding. |
| FILED | Monday, July 09, 2007 |
| APPL NO | 12/307878 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/524 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198368 | Thayumanavan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Sankaran Thayumanavan (Amerst, Massachusetts); Akamol Klaikherd (Amherst, Massachusetts); Suhrit Ghosh (Kolkata, India) |
| ABSTRACT | Cleavable, disulfide-coupled block copolymers as can be used in the preparation of nanoporous thin films, micellar configurations and related structures. |
| FILED | Friday, October 17, 2008 |
| APPL NO | 12/253535 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 525/92.J00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198436 | Raymo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of Miami (Miami, Florida) |
| INVENTOR(S) | Francisco M. Raymo (Coral Gables, Florida); Massimiliano Tomasulo (Miami, Florida) |
| ABSTRACT | A chromogenic oxazine compound for the colorimetric detection of cyanide was designed. Indeed, the [1,3]oxazine ring of our compound opens to form a phenolate chromophore in response to cyanide. The heterocyclic com-pound may be comprised of fused benzooxazine and indoline rings: wherein R1 is an alkyl (e.g., methyl, ethyl, propyl, isopropyl, butyl, isobutyl), a substituted alkyl, a cycloalkyl (e.g., cyclopentyl, cyclohexyl), a substituted cycloalkyl, an aryl (e.g., phenyl), or a substituted aryl and R2 is a chromophore (e.g., nitroso, nitro, azo dyes). This quantitative chromogenic transformation permits the detection of micromolar concentrations of cyanide in water. Furthermore, our chromogenic oxazine is insensitive to the presence of large concentrations of fluoride, chloride, bromide or iodide anions, which are generally the principal interferents in the colorimetric detection of cyanide. |
| FILED | Friday, September 01, 2006 |
| APPL NO | 11/991355 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199048 | Medina Sanchez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Rafael H. Medina Sanchez (Amherst, Massachusetts) |
| ABSTRACT | A method for calibrating a phased-array antenna that involves transmitting a signal from a transmitting element, and sequentially receiving the transmitted signal at two receiving elements each spaced a first distance from the transmitting element. This step is then repeated one or more times, but transmitting from a different transmitting element in each repetition of the step, until each element being calibrated has received at least one transmission. Then, the first distance is changed to a second distance, and the steps are repeated one or more times to gather additional measurements. These measurements allow the determination from the received signals of two separate element mutual coupling ratios, one ratio for one subset of the elements being calibrated and the other for a second subset comprising the remaining elements being calibrated. Next, at least four additional transmissions and receptions are made via two transmissions each from two transmitting elements comprising one element of each subset, and the reception of transmissions from each of these two transmitting elements by each of two receiving elements, the two receiving elements being different elements than the two transmitting elements. From these last measurements a complex calibration ratio for all of the elements being calibrated with respect to a single element is determined. For calibration in the transmit mode, this same procedure is followed, but the transmissions become receptions and the receptions become transmissions. |
| FILED | Wednesday, December 15, 2010 |
| APPL NO | 12/968446 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/174 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199244 | Baraniuk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard G. Baraniuk (Houston, Texas); Dror Z. Baron (Cary, North Carolina); Marco F. Duarte (Durham, North Carolina); Kevin F. Kelly (Houston, Texas); Courtney C. Lane (Ventura, California); Jason N. Laska (Houston, Texas); Dharmpal Takhar (Houston, Texas); Michael B. Wakin (Castle Rock, Colorado) |
| ABSTRACT | A new digital image/video camera that directly acquires random projections of the incident light field without first collecting the pixels/voxels. In one preferred embodiment, the camera employs a digital micromirror array to perform optical calculations of linear projections of an image onto pseudorandom binary patterns. Its hallmarks include the ability to obtain an image with only a single detection element while measuring the image/video fewer times than the number of pixels or voxels—this can significantly reduce the computation required for image/video acquisition/encoding. Since the system features a single photon detector, it can also be adapted to image at wavelengths that are currently impossible with conventional CCD and CMOS imagers. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791171 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Television 348/335 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08199580 | Leburton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Jean-Pierre Leburton (Urbana, Illinois); Jeanlex Soares De Sousa (Fortaleza, Brazil); Gil De Aquino Farias (Fortaleza, Brazil); Valder Nogueira Freire (Fortaleza, Brazil) |
| ABSTRACT | A system that incorporates teachings of the present disclosure may include, for example, a memory device having a memory cell to selectively store holes by photon and bias voltage induction as a representation of binary values. |
| FILED | Tuesday, February 24, 2009 |
| APPL NO | 12/391651 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/185.180 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200325 | Sarpeshkar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Rahul Sarpeshkar (Arlington, Massachusetts); Benjamin I. Rapoport (New York, New York); Woradorn Wattanapanitch (Cambridge, Massachusetts) |
| ABSTRACT | A micropower neural amplifier with adaptive power biasing for use in multi-electrode arrays is provided. The micropower neural amplifier includes a low noise gain stage. The low noise gain stage is implemented using an amplifier and pseudoresistor elements. |
| FILED | Tuesday, May 27, 2008 |
| APPL NO | 12/127475 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200466 | Spilker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Ryan Leonard Spilker (Stanford, California); Chales Anthony Taylor, Jr. (Menlo Park, California) |
| ABSTRACT | Computational methods are used to create cardiovascular simulations having desired hemodynamic features. Cardiovascular modeling methods produce descriptions of blood flow and pressure in the heart and vascular networks. Numerical methods optimize and solve nonlinear equations to find parameter values that result in desired hemodynamic characteristics including related flow and pressure at various locations in the cardiovascular system, movements of soft tissues, and changes for different physiological states. The modeling methods employ simplified models to approximate the behavior of more complex models with the goal of to reducing computational expense. The user describes the desired features of the final cardiovascular simulation and provides minimal input, and the system automates the search for the final patient-specific cardiovascular model. |
| FILED | Monday, July 21, 2008 |
| APPL NO | 12/219398 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08201090 | Beitle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Robert R. Beitle (Fayetteville, Arkansas); Noel Romey (Cabot, Arkansas); Steven Setzer (Rogers, Arkansas); H. Michael Cheung (Hudson, Ohio) |
| ABSTRACT | A user interface for software applications enables the full use of graphical user interface (GUI) software, particularly engineering design software, by visually impaired individuals. The interface combines tactile representations of graphical elements, non-visual cues, and a hardware element to allow the effective placement and interconnection of graphic elements using design software. |
| FILED | Thursday, November 13, 2008 |
| APPL NO | 12/269965 |
| ART UNIT | 2141 — Graphical User Interface and Document Processing |
| CURRENT CPC | Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/702 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08196853 | Bland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Geoffrey L. Bland (Wallops, Virginia); Ted K. Miles (Onancock, Virginia) |
| ABSTRACT | A suspension apparatus for suspending instrumentation from an airborne platform may include a generally longitudinal boom having a payload end and a tail end. Yaw and pitch stabilizers may be disposed at the tail end of the boom. A mast that may be selectively translatable on the boom may connect the boom to a tether line of the airborne platform. The payload may be attached to the payload end of the boom. The mast may be positioned axially along the boom at the center of gravity of the combination of the payload, boom, pitch stabilizer, and yaw stabilizer. |
| FILED | Thursday, May 13, 2010 |
| APPL NO | 12/779494 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/1.TD0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08196858 | Croom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Croom (Yorktown, Virginia); Stephen C. Smith (Cupertino, California); Paul A. Gelhausen (Yorktown, Virginia); Mark D. Guynn (Yorktown, Virginia); Craig A. Hunter (Williamsburg, Virginia); David A. Paddock (Toano, Virginia); Steven E. Riddick (Hampton, Virginia); John E. Teter, Jr. (Hampton, Virginia) |
| ABSTRACT | An aircraft is configured for flight in an atmosphere having a low density. The aircraft includes a fuselage, a pair of wings, and a rear stabilizer. The pair of wings extends from the fuselage in opposition to one another. The rear stabilizer extends from the fuselage in spaced relationship to the pair of wings. The fuselage, the wings, and the rear stabilizer each present an upper surface opposing a lower surface. The upper and lower surfaces have X, Y, and Z coordinates that are configured for flight in an atmosphere having low density. |
| FILED | Thursday, March 11, 2010 |
| APPL NO | 12/721833 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/45.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197249 | Nguyen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Quang-Viet Nguyen (Richmond Heights, Ohio) |
| ABSTRACT | A low-emissions high-pressure multi-fuel burner includes a fuel inlet, for receiving a fuel, an oxidizer inlet, for receiving an oxidizer gas, an injector plate, having a plurality of nozzles that are aligned with premix face of the injector plate, the plurality of nozzles in communication with the fuel and oxidizer inlets and each nozzle providing flow for one of the fuel and the oxidizer gas and an impingement-cooled face, parallel to the premix face of the injector plate and forming a micro-premix chamber between the impingement-cooled face and the in injector face. The fuel and the oxidizer gas are mixed in the micro-premix chamber through impingement-enhanced mixing of flows of the fuel and the oxidizer gas. The burner can be used for low-emissions fuel-lean fully-premixed, or fuel-rich fully-premixed hydrogen-air combustion, or for combustion with other gases such as methane or other hydrocarbons, or even liquid fuels. |
| FILED | Friday, April 28, 2006 |
| APPL NO | 11/412935 |
| ART UNIT | 3743 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Combustion 431/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197578 | Hruby et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Busek Company, Inc. (Natick, Massachusetts) |
| INVENTOR(S) | Vladimir J. Hruby (Newton, Massachusetts); Nate Demmons (Mason, New Hampshire); Tom Roy (Newton, Massachusetts); Doug Spence (Brookline, Massachusetts); Eric Ehrbar (Brookline, Massachusetts); Jurg Zwahlen (New Ipswich, New Hampshire); Charles Gasdaska (Shrewsbury, Massachusetts) |
| ABSTRACT | A liquid degasser for a space device including a gas permeable material configured for contact with a flow of liquid to be de-gassed on one side and a vacuum on the other side, and wherein the gas permeable material allows gas in the liquid to diffuse to the vacuum to remove the gas from the liquid. |
| FILED | Wednesday, July 25, 2007 |
| APPL NO | 11/881020 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation: Apparatus 096/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08197722 | Marder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Seth Marder (Pasadena, California); Joseph Perry (Pasadena, California) |
| ABSTRACT | Compositions capable of simultaneous two-photon absorption and higher order absorptivities are provided. Compounds having a donor-pi-donor or acceptor-pi-acceptor structure are of particular interest, where the donor is an electron donating group, acceptor is an electron accepting group, and pi is a pi bridge linking the donor and/or acceptor groups. The pi bridge may additionally be substituted with electron donating or withdrawing groups to alter the absorptive wavelength of the structure. Also disclosed are methods of generating an excited state of such compounds through optical stimulation with light using simultaneous absorption of photons of energies individually insufficient to achieve an excited state of the compound, but capable of doing so upon simultaneous absorption of two or more such photons. Applications employing such methods are also provided, including controlled polymerization achieved through focusing of the light source(s) used. |
| FILED | Monday, July 30, 2001 |
| APPL NO | 09/918874 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/586 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198956 | U-Yen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Kongpop U-Yen (Alexandria, Virginia); Edward J. Wollack (Clarksville, Maryland) |
| ABSTRACT | A compact planar microwave blocking filter includes a dielectric substrate and a plurality of filter unit elements disposed on the substrate. The filter unit elements are interconnected in a symmetrical series cascade with filter unit elements being organized in the series based on physical size. In the filter, a first filter unit element of the plurality of filter unit elements includes a low impedance open-ended line configured to reduce the shunt capacitance of the filter. |
| FILED | Wednesday, August 05, 2009 |
| APPL NO | 12/535954 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/176 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198976 | Thomsen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Donald Laurence Thomsen (Yorktown, Virginia) |
| ABSTRACT | A flexible thin metal film thermal sensing system is provided. A thermally-conductive film made from a thermally-insulating material is doped with thermally-conductive material. At least one layer of electrically-conductive metal is deposited directly onto a surface of the thermally-conductive film. One or more devices are coupled to the layer(s) to measure an electrical characteristic associated therewith as an indication of temperature. |
| FILED | Friday, January 15, 2010 |
| APPL NO | 12/688309 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical resistors 338/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200486 | Jorgensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (NASA) (Washington, District of Columbia) |
| INVENTOR(S) | Charles C. Jorgensen (Palo Alto, California); Diana D. Lee (Palo Alto, California); Shane T. Agabon (Millbrae, California) |
| ABSTRACT | Method and system for processing and identifying a sub-audible signal formed by a source of sub-audible sounds. Sequences of samples of sub-audible sound patterns (“SASPs”) for known words/phrases in a selected database are received for overlapping time intervals, and Signal Processing Transforms (“SPTs”) are formed for each sample, as part of a matrix of entry values. The matrix is decomposed into contiguous, non-overlapping two-dimensional cells of entries, and neural net analysis is applied to estimate reference sets of weight coefficients that provide sums with optimal matches to reference sets of values. The reference sets of weight coefficients are used to determine a correspondence between a new (unknown) word/phrase and a word/phrase in the database. |
| FILED | Thursday, June 05, 2003 |
| APPL NO | 10/457696 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/233 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08197979 | Badding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Corning Incorporated (Corning, New York) |
| INVENTOR(S) | Michael Edward Badding (Campbell, New York); Jacqueline Leslie Brown (Lindley, New York); Steven F Hoysan (Cypress, Texas); Thomas Dale Ketcham (Big Flats, New York); Scott Christopher Pollard (Big Flats, New York); Dell Joseph St Julien (Watkins Glen, New York); Sujanto Widjaja (Corning, New York) |
| ABSTRACT | A solid oxide fuel cell comprising a thin ceramic electrolyte sheet having an increased street width is disclosed. Also disclosed are solid oxide fuel cells comprising: a substantially flat ceramic electrolyte sheet, a substantially flat ceramic electrolyte sheet having a seal area of greater thickness than the active area of the electrolyte sheet, a ceramic electrolyte sheet that overhangs the seal area, a ceramic electrolyte sheet and at least one substantially flat border material, and a border material having a non-linear edge. Methods of making a solid oxide fuel cell in accordance with the disclosed embodiments are also disclosed. Also disclosed are methods of making a solid oxide fuel cell wherein the seal has a uniform thickness, wherein the seal is heated to remove a volatile component prior to sealing, and wherein the distance between the frame and the ceramic electrolyte sheet of the device is constant. |
| FILED | Wednesday, December 05, 2007 |
| APPL NO | 11/999350 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/463 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198486 | Cortright |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Virent, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Randy D. Cortright (Madison, Wisconsin) |
| ABSTRACT | Disclosed are methods for generating propylene glycol, ethylene glycol and other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols from biomass using hydrogen produced from the biomass. The methods involve reacting a portion of an aqueous stream of a biomass feedstock solution over a catalyst under aqueous phase reforming conditions to produce hydrogen, and then reacting the hydrogen and the aqueous feedstock solution over a catalyst to produce propylene glycol, ethylene glycol and the other polyols, diols, ketones, aldehydes, carboxylic acids and alcohols. The disclosed methods can be run at lower temperatures and pressures, and allows for the production of oxygenated hydrocarbons without the need for hydrogen from an external source. |
| FILED | Tuesday, June 28, 2011 |
| APPL NO | 13/170757 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 568/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08196442 | Lassen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | David Lassen (Arnold, Maryland); Charles F. Pribyl (Ralto, Maryland) |
| ABSTRACT | A reusable tamper indicating bag closure for transporting most items in a bag such as documents and portable computing devices including laptops, PDAs, mobile phones, iPods® . . . etc. that would appeal to a broad spectrum of customers including the individual buyer, the business user, and the government user. The tamper-evident bag closure is defined by a lid with multiple hasps and a base with knobs that attach to the bag and is secured by a locking mechanism placed through an opening on the base and inserted within an insertion aperture such that locking the lock mechanism causes the lid to slide into alignment with the base and engages the plurality of hasps with the plurality of knobs thus securing the bag. The bag closure also has several tamper indicating features including the use of tamper indicating markers, wire seals and tamper indicating labels. |
| FILED | Wednesday, February 24, 2010 |
| APPL NO | 12/661193 |
| ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Locks 070/64 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08200731 | Cusmariu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Adolf Cusmariu (Eldersburg, Maryland) |
| ABSTRACT | A device for and method of determining a coherence measurement for a signal that includes a digitizer for digitizing the signal, a transformer connected to the digitizer, a first squarer connected to the transformer, a second squarer connected to the digitizer, an adder connected to the first squarer and the second squarer, a subtractor connected to the first squarer and the second squarer, a standard-deviation function block connected to the subtractor, a mean generator connected to the adder, a first multiplier connected to the standard-deviation function block, and a divider connected to the output of the mean generator and the first multiplier. |
| FILED | Thursday, November 20, 2008 |
| APPL NO | 12/313397 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/422 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08198249 | Nair et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (Lansing, Michigan) |
| INVENTOR(S) | Muraleedharan G. Nair (Okemos, Michigan); Bolleddula Jayaprakasam (East Lansing, Michigan); Lawrence K. Olson (East Lansing, Michigan); Robert E. Schutzki (Eaton Rapids, Michigan) |
| ABSTRACT | A process of enhancing insulin excretion in a subject includes administering to the subject a polyphenol active ingredient. The polyphenol active ingredient is a purified cyanidin-3-glycoside alone or purified cyanidin alone. The pharmaceutically acceptable carrier is administered with the polyphenol active ingredient. |
| FILED | Tuesday, May 04, 2010 |
| APPL NO | 12/773277 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 08199975 | Pomerleau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cognex Corporation (Natick, Massachusetts) |
| INVENTOR(S) | Dean Arthur Pomerleau (Gibsonia, Pennsylvania); Jay W. Gowdy (Gibsonia, Pennsylvania); Matthew Troup (Gibsonia, Pennsylvania); Sanjay Nichani (San Diego, California) |
| ABSTRACT | This invention provides a system and method for object detection and collision avoidance for objects and vehicles located behind the cab or front section of an elongated, and possibly tandem, vehicle. Through the use of narrow-baseline stereo vision that can be vertically oriented relative to the ground/road surface, the system and method can employ relatively inexpensive cameras, in a stereo relationship, on a low-profile mounting, to perform reliable detection with good range discrimination. The field of detection is sufficiently behind and aside the rear area to assure an adequate safety zone in most instances. Moreover, this system and method allows all equipment to be maintained on the cab of a tandem vehicle, rather than the interchangeable, and more-prone-to-damage cargo section and/or trailer. One or more cameras can be mounted on, or within, the mirror on each side, on aerodynamic fairings or other exposed locations of the vehicle. Image signals received from each camera can be conditioned before they are matched and compared for disparities viewed above the ground surface, and according to predetermined disparity criteria. |
| FILED | Wednesday, December 12, 2007 |
| APPL NO | 11/954513 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Federal Reserve Bank (FED)
| US 08196814 | Mueller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Federal Reserve Bank of Dallas (Dallas, Texas); Federal Reserve Bank of Kansas City (Kansas City, Missouri); Federal Reserve Bank of Atlanta (Atlanta, Georgia); Federal Reserve Bank of Cleveland (Cleveland, Ohio) |
| INVENTOR(S) | Randall Lee Mueller (Kansas City, Missouri); Thomas Edwin Schaadt (Westerville, Ohio); V. Srinivas Nori (Norcross, Georgia); Steven Q. Purser (Plano, Texas); Diane Marie Baggett (Westminster, Colorado) |
| ABSTRACT | Producing print streams for efficiently generating properly formatted and ordered paper cash letters comprises print stream file that includes electronic form definitions for each cash letter document. The cash letter documents can include a cover page, one or more bundles of substitute checks, a bundle summary for each substitute check bundle, and/or a cash letter bundle summary. Information from an electronic image cash letter file can be input in data fields of the electronic form definitions. Printing the information in the print stream file results in a properly formatted and ordered paper cash letter including substitute checks and audit data. Each substitute check can include all of the MICR data provided on a corresponding, original paper check. The audit data includes the cover page, bundle summary(ies), and/or cash letter bundle summary, which can each detail the documents printed concurrently therewith. |
| FILED | Wednesday, March 24, 2010 |
| APPL NO | 12/730471 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Registers 235/379 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 08201181 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Duong Nguyen (Denver, Colorado); Michael T. Hampton (Naperville, Illinois); Anthony M. Janoso (Littleton, Colorado) |
| ABSTRACT | A system for sensor scheduling includes a plurality of sensors operable to perform one or more tasks and a processor operable to receive one or more missions and one or more environmental conditions associated with a respective mission. Each mission may include one or more tasks to be performed by one or more of the plurality of sensors. The processor is further operable to select one or more of the plurality of sensors to perform a respective task associated with the respective mission. The processor may also schedule the respective task to be performed by the selected one or more sensors. The scheduling is based at least on a task value that is determined based on an options pricing model. The options pricing model is based at least on the importance of the respective task to the success of the respective mission and one or more scheduling demands. |
| FILED | Friday, August 31, 2007 |
| APPL NO | 11/849016 |
| ART UNIT | 2195 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 08199226 | McCloskey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Scott McCloskey (Minneapolis, Minnesota) |
| ABSTRACT | Methods and systems for capturing an image of a moving subject employ a camera image sensor that captures a blurred image of a moving subject. In-capture positions of the moving object are also determined using a high frame rate camera or other motion sensing device. The PSF for controlling modulation of the light hitting the camera image is successively updated by selecting, from among a plurality of pre-computed invertible PSFs, a pre-computed invertible PSFs for each estimated motion of the moving object. Light hitting the camera image sensor is modulated in capture phase according to one or more of the updated pre-computed invertible PSFs such that the captured blurred image is invertible. The resulting invertible blurred image can be de-blurred using the selected known PSFs to provide a substantially sharp image. |
| FILED | Tuesday, September 21, 2010 |
| APPL NO | 12/886638 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Television 348/248 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08198231 | Climo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Nutrition 21, Inc. (Purchase, New York) |
| INVENTOR(S) | Michael Climo (Richmond, Virginia); Ellen Murphy (Bronx, New York); Gordon Archer (Richmond, Virginia) |
| ABSTRACT | Co-administration of a lysostaphin or other anti-staphylococcal agent which cleaves cross-links of peptidoglycans of staphylococci cell walls such as lysostaphin and an antibiotic effective against staphylococci due to antibiotic activity mediated by cell-wall activity is effective against staphylococcal infection, even staphylococci that may be resistant to one or other of lysostaphin or the cell-wall active antibiotic. Co-administration simultaneously suppresses the generation of antibiotic-resistant mutant strains. Effective cell-wall active antibiotics include β-lactams and glycopeptides. |
| FILED | Friday, June 02, 2006 |
| APPL NO | 11/445289 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08197205 | Rudley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Frank M. Rudley (Lester, Pennsylvania); Evhen M. Mychalowycz (Swarthmore, Pennsylvania); Joseph R. Wagner, Jr. (East Norriton, Pennsylvania); Edward J. Glembocki (Media, Pennsylvania) |
| ABSTRACT | A blade actuation system comprises at least one motor coupled to a rotor blade for changing the pitch angle of the rotor blade. The motor is configured to wirelessly communicate with at least one flight control computer to modulate the pitch angle. At least one generator may be mounted on a rotor shaft to generate power during rotation of the rotor shaft. The generator may provide power to the motor. The flight control computer is operative to provide control signals to at least one of the generators and motors for regulation thereof. The flight control computer, motor and generator may be configured to wirelessly communicate with one another. |
| FILED | Thursday, April 24, 2008 |
| APPL NO | 12/108516 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198323 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The University of Rochester Medical Center (Rochester, New York); Androscience Corporation (San Diego, California) |
| INVENTOR(S) | Kuo-Hsiung Lee (Chapel Hill, North Carolina); Li Lin (Chapel Hill, North Carolina); Charles C-Y Shih (Solana Beach, California); Ching-Yuan Su (San Diego, California); Junko Ishida (Tokyo, Japan); Hironori Ohtsu (Matsubara, Japan); Hui-Kang Wang (San Diego, California); Hideji Itokawa (Chapel Hill, North Carolina); Chawnshang Chang (Pittsford, New York) |
| ABSTRACT | The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired. |
| FILED | Monday, April 12, 2010 |
| APPL NO | 12/758462 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/543 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08198403 | Dieckmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Gregg R. Dieckmann (Plano, Texas); Alfonzo Ortiz-Acevedo (El Paso, Texas); Ray Baughman (Dallas, Texas); Alan B. Dalton (Shamley Green, United Kingdom); Rockford K. Draper (Plano, Texas); Inga H. Musselman (Dallas, Texas) |
| ABSTRACT | The present invention includes compositions and methods for the isolation, separation and chelation of Carbon Nanotubes (CNTs) using a cyclizable peptide. |
| FILED | Friday, May 26, 2006 |
| APPL NO | 11/441480 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/317 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP22781 | Moore |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Washington State University Research Foundation (Pullman, Washington) |
| INVENTOR(S) | Patrick P. Moore (Puyallup, Washington) |
| ABSTRACT | This invention relates to a new and distinct cultivar of strawberry plant (Fragaria×ananassa Duch) named ‘Puget Crimson’. ‘Puget Crimson’ is a late season, June-bearing (short-day) cultivar adapted to the Pacific Northwest. ‘Puget Crimson’ is distinguished by its upright growth habit, strong vigor, large fruit that is longer than wide, high yields of very late season production and an excellent strong strawberry flavor. |
| FILED | Thursday, February 03, 2011 |
| APPL NO | 12/931592 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/208 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 12, 2012.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2012/fedinvent-patents-20120612.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page