FedInvent™ Patents

Patent Details for Tuesday, August 21, 2012

This page was updated on Monday, March 27, 2023 at 03:24 AM GMT

Department of Defense (DOD)

08245370 — Docking system

US 08245370	Ritter et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	Michigan Aerospace Corporation (Ann Arbor, Michigan)
INVENTOR(S)	Greg Alan Ritter (Hamburg, Michigan); Anthony Beckman Hays (Jackson, Michigan); Peter Tchoryk, Jr. (Ann Arbor, Michigan); Jane Camile Pavlich (Ann Arbor, Michigan); Gregory Joseph Wassick (Petersburg, Michigan)
ABSTRACT	A capture mechanism provides for receiving a necked coupling element within a socket, providing for the necked coupling element to slide therewith, biasing a latch lever in an open position so as to provide for receiving the necked coupling element within the socket adjacent to the latch lever, rotating the latch lever with the necked coupling element from the open position to a closed position as the necked coupling element is slid within the socket towards a bottom of the socket, biasing a latch lock against the latch lever, engaging the latch lock with the latch lever when the latch lever is in the closed position so as to provide for latching the latch lever in the closed position and capturing the necked coupling element within the socket, and providing for unlatching the latch lever by releasing the latch lock from engagement with the latch lever.
FILED	Sunday, November 02, 2008
APPL NO	12/263498
ART UNIT	3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Buckles, buttons, clasps, etc. 024/645
VIEW PATENT	@ USPTO: Full Text PDF

08245585 — Modulated pressure wave vapor generator

US 08245585	Szabo et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Sensors Directorate (AFRL/PKSE) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Night Vision and Electronic Sensors Directorate (NVESD)
APPLICANT(S)
ASSIGNEE(S)	FLIR Systems, Inc. (Wilsonville, Oregon)
INVENTOR(S)	Matthew Joseph Szabo (Stillwater, Oklahoma); Matthew Laurence Dock (Stillwater, Oklahoma); Craig Allen Aker (Stillwater, Oklahoma)
ABSTRACT	The current invention provides a modulated pressure wave vapor generator suitable for use outside of the laboratory. The vapor generator of the current invention produces a controlled analyte vapor sample without using bulk movement of gas. Additionally, the current invention compensates for changes in the environment to ensure discharge of the preferred volume of analyte from the vapor generator. Finally, the current invention provides a method for generating a controlled volume of analyte vapor suitable for calibrating vapor sensors.
FILED	Thursday, June 10, 2010
APPL NO	12/797772
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/863.10
VIEW PATENT	@ USPTO: Full Text PDF

08245617 — Non-lethal restraint device with diverse deployability applications

US 08245617	Martinez et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)	Engineering Science Analysis Corporation (Tempe, Arizona)
INVENTOR(S)	Martin A. Martinez (Phoenix, Arizona); Patrick J. Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California)
ABSTRACT	An immobilization device and method of restraining vehicles, persons and animals uses tendrils attached to various devices to engage the target. The immobilization device, system and method includes a housing containing launchable tendrils that are launched from the housing by a propellant. The tendrils may be attached to straps or other elements carried by the immobilization device. The tendrils will engage the target and restrain it if it is a vehicle such as a car, truck, boat, submarine, or like vehicle. In stopping a person or animal the tendrils will deliver a marking package, a shocking package or a snare package to mark, shock or snare the target. Straps may be pulled off the housing leaving the housing near the point of deployment.
FILED	Tuesday, July 20, 2010
APPL NO	12/839911
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ordnance 089/1.340
VIEW PATENT	@ USPTO: Full Text PDF

08245624 — Decoupled multiple weapon platform

US 08245624	Green
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Andrew Walter Green (King George, Virginia)
ABSTRACT	A Decoupled Elevation, Automatic Drift Correction (DEADCo) Multiple Weapon System is provided for concurrently engaging line-of-sight and indirect-fire weapons against a target. The DEADCo system includes a turret structure, a first cradle and a second cradle. The turret structure is mountable to a vehicle and rotatable in yaw on a turret training drive. The first cradle is mountable to the turret structure. The first cradle has a fire control system, and a first elevation drive rotatable in pitch on which to pivotably mount the line-of-sight weapon. The fire control system relays pointer commands to the first elevation drive. The second cradle is mountable to the turret structure. The second cradle includes a drift correction drive rotatable in yaw and a second elevation drive rotatable in pitch. The fire control system relays the pointer commands to the drift correction and second elevation drives that compensate for drift. The deflection weapon couples to the drift correction and second elevation drives for independent rotations in pitch and yaw.
FILED	Thursday, August 26, 2010
APPL NO	12/807374
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ordnance 089/41.150
VIEW PATENT	@ USPTO: Full Text PDF

08245640 — Melted metal dispersal warhead

US 08245640	Sutherland et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gerrit T. Sutherland (White Plains, Maryland); Phillip J. Miller (Issue, Maryland); Harold W. Sandusky (Fulton, Maryland)
ABSTRACT	Molten droplets of a metal fuel, such as aluminum, are dispersed into air or water for a reaction releasing energy for military or other purposes. In one warhead embodiment, a cylinder of solid metal is disposed within a ceramic heat insulator; heaters of thermite-like material are embedded in the metal; and an explosive dispersing charge is disposed around or at one end of the cylinder. On activation, the heaters are ignited to melt the metal, and the charge then detonated to disperse droplets of the molten metal. In a related embodiment, the metal and heaters are within a containment having an atomizing nozzle at one end and, oppositely of the metal from the nozzle, a piston and gas generator. When the metal is melted, the gas generator is activated to expel molten metal droplets from the nozzle. The fuel may be pressed particles heated below the melting point and then dispersed by a charge providing enough heat to melt the particles; may be a single component, fuel-rich thermite compound; and may include droplet surface tension reducing additives. Advantages are that the weight and volume of a warhead do not include explosives, binders, and underwater-use oxidizers employed with fuel particles in conventional energetic materials. A warhead may thus have greater density for effective penetration; and, since the fuel is not incorporated in an explosive, dispersing charges can be removed until use, and metal fuels hazardous when incorporated in an explosive can be used.
FILED	Tuesday, May 12, 2009
APPL NO	12/454487
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ammunition and explosives 12/205
VIEW PATENT	@ USPTO: Full Text PDF

08245713 — Convertible patient isolation pod

US 08245713	Paschal, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Charles R. Paschal, Jr. (Frederick, Maryland); Orlando J. Illi, Jr. (Frederick, Maryland); George W. Haubeil (Front Royal, Virginia); James R. Gauger (Highland Park, Illinois); Robert L. Mullins (Hazel Crest, Illinois)
ABSTRACT	A convertible isolation pod for an individual patient formed from sealable flexible plastic sheeting including an air intake grommet at the head end and an air exhaust grommet at the foot end of the pod each of the grommets being equipped with a valve to provide unidirectional air flow within the pod where the air is filtered to remove contaminants.
FILED	Tuesday, May 07, 2002
APPL NO	10/139513
ART UNIT	3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Surgery 128/845
VIEW PATENT	@ USPTO: Full Text PDF

08245731 — Microfluidic devices with separable actuation and fluid-bearing modules

US 08245731	Welle
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Richard P. Welle (Huntington Beach, California)
ABSTRACT	A fluid transport/containment apparatus includes a fluid-bearing module and an actuation module. The fluid-bearing module includes a substrate and fluid transport/containment elements distributed therein, with one or more of the fluid transport/containment elements having microfluidic dimensions. The actuation module is detachably secured to the fluid-bearing module such that the actuation elements are operatively interfaced with the fluid transport/containment elements.
FILED	Monday, July 19, 2010
APPL NO	12/839339
ART UNIT	3753 — Fluid Handling and Dispensing
CURRENT CPC	Fluid handling 137/828
VIEW PATENT	@ USPTO: Full Text PDF

08245874 — Slider-hinge door

US 08245874	Fowler, IV
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert J. Fowler, IV (Fredericksburg, Virginia)
ABSTRACT	A mechanism is provided for connecting a door to a container. The door provides and restricts access to a chamber of the container in respective open and closed positions. The mechanism includes, at each corresponding lateral side of the container and the door, a rail mounted to the container, an elbow, and first and second linkage arms. The rail aligns along a fore-and-aft direction so that the elbow slides along that direction. The elbow has vertical and axial members. The axial member connects to the rail. The first linkage arm includes first, second and third joints that pivotably connect respectively to the vertical member, to the container, and to the door. The second linkage arm includes fourth and fifth joints that pivotably connect respectively to the door and to the container. The linkage arms are disposed to avoid lateral obstruction beyond the door in the open position.
FILED	Thursday, May 12, 2011
APPL NO	13/068908
ART UNIT	3728 — Fluid Handling and Dispensing
CURRENT CPC	Receptacles 220/812
VIEW PATENT	@ USPTO: Full Text PDF

08245945 — System and method of tagging an ordnance

US 08245945	Stimek et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S)	Williams-Pyro, Inc. (Fort Worth, Texas)
INVENTOR(S)	Christopher M. Stimek (Fort Worth, Texas); Roger Q. Paulsel (Weatherford, Texas)
ABSTRACT	A method and system for attaching a radio frequency identification (RFID) tag to an ordnance is provided. By tailoring the packaged tag and electronics to accommodate existing ordnance body cavities the integrity of the bomb casing is maintained. Likewise, fin assemblies also remain intact and are mounted in a conventional manner to the tagged ordnance. Numerous ordnance types, to include the mark (MK) 80 series general purpose bombs and equivalents are compatible with the tagging method and system described herein. Set screw mounted tail assemblies of various fin configurations are readily assembled onto the metal body casings of tagged ordnances. A curved dipole antenna provides access to external query signals and transmission of tag locating signals. As described herein, tag antennas can mount between ordnance assembly parts, adding to the ease of retrofitting existing ordnance inventory for a RFID tag localizing system.
FILED	Saturday, March 17, 2012
APPL NO	13/423191
ART UNIT	2887 — Optics
CURRENT CPC	Registers 235/492
VIEW PATENT	@ USPTO: Full Text PDF

08245968 — Method and apparatus for retrieving a hovering aircraft

US 08245968	McGeer et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	Aeroval Corporation (White Salmon, Washington)
INVENTOR(S)	Brian T. McGeer (Underwood, Washington); Andreas H. von Flotow (Hood River, Oregon); Corydon C. Roeseler (Hood River, Oregon)
ABSTRACT	For retrieval of a hovering aircraft, a cable, bar, or similar fixture is suspended in an approximately horizontal orientation across the retrieval area between two well-separated supports. The aircraft slowly flies into this fixture, which then slides along the aircraft in a direction approximately parallel with the aircraft's thrust line. This leads to the aircraft becoming fastened to the fixture by an interceptor or aircraft capturer, which in alternative embodiments are respectively on the aircraft or the fixture or both. Thrust is then reduced, and the aircraft comes to rest hanging from the fixture for subsequent removal. Retrieval is thus accomplished with simple and economical apparatus, light and unobtrusive elements on the aircraft, low risk of damage, and only moderate piloting accuracy.
FILED	Thursday, February 10, 2011
APPL NO	13/024843
ART UNIT	3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeronautics and astronautics 244/110.C00
VIEW PATENT	@ USPTO: Full Text PDF

08246298 — Borescope boss and plug cooling

US 08246298	Wilson
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Barry Allan Wilson (Liberty Township, Ohio)
ABSTRACT	A coolable borescope boss includes cooling passages extending through the boss and oriented for spraying cooling air into a hole extending through the boss. Centerlines of the cooling passages may intersect the a hole axis of the hole. The cooling passages may be cylindrical or open slots disposed through the boss. The boss may be on an arcuate gas turbine engine shroud segment circumscribed about an axial centerline axis. The segment may be part of an annular segmented turbine shroud having cylindrical shroud first and second sections and a conical shroud midsection therebetween and the segment having cylindrical segment first and second sections and a conical segment midsection therebetween. A hole exit of the hole being flush with the conical segment midsection. A borescope plug tip having a spherical tip chamfer may be used to seal against a conical boss chamfer of the boss.
FILED	Thursday, February 26, 2009
APPL NO	12/393084
ART UNIT	2892 — Semiconductors/Memory
CURRENT CPC	Rotary kinetic fluid motors or pumps 415/116
VIEW PATENT	@ USPTO: Full Text PDF

08246303 — Active twist hollow beam system

US 08246303	Thomas et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	James P Thomas (Alexandria, Virginia); Michael J O'Brien (Los Angeles, California); William R Pogue, III (Easton, Maryland)
ABSTRACT	A system for actively controlling the span-wise rotational twist of a hollow beam along its longitudinal axis, including a hollow beam structure having a leading edge and a trailing edge region, the beam being split along its length, an actuator arranged between split surfaces of the beam, the actuator adapted to move the split surfaces in a longitudinal direction relative to each other, inducing a twist in the beam. In one embodiment, the actuator is a plurality of thermal expansion material blocks alternating with mechanical compression blocks, the thermal expansion material blocks being heated to cause expansion in the spanwise longitudinal direction. Other alternative actuators include a rotary actuators such as a threaded screw, piezoelectric or magnetostrictive blocks, a hydraulic actuator, or a pneumatic actuator. In an embodiment, the beam is an airfoil shape.
FILED	Thursday, September 18, 2008
APPL NO	12/233244
ART UNIT	2891 — Semiconductors/Memory
CURRENT CPC	Fluid reaction surfaces 416/23
VIEW PATENT	@ USPTO: Full Text PDF

08246462 — Hall-effect finger-mounted computer input device

US 08246462	Tran et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Nghia Tran (San Diego, California); Michael R. Blackburn (Encinitas, California); Hoa V. Phan (Escondido, California)
ABSTRACT	A Hall-effect system for providing inputs into a processor includes at least one magnet for establishing a magnetic field, a remote sensor unit and a receive station. The magnet is sized and adapted to be worn on a user's finger, while the remote sensor unit is adapted to be worn on a user's thumb. The remote sensor unit includes a Hall-effect sensor that senses changes in the magnetic field due to the motion of the magnet relative to the Hall-effect sensor. The Hall-effect sensor detects the magnetic field changes, and the remote sensor unit generates a sensor output corresponding to the magnetic field changes. The receive station is connected to the processor. The receive station receives the output from the remote sensor unit and converts the sensor output into an input for the processor.
FILED	Tuesday, June 02, 2009
APPL NO	12/476301
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Amusement devices: Games 463/37
VIEW PATENT	@ USPTO: Full Text PDF

08246720 — Electrostatic aerosol concentrator

US 08246720	Pant et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S)	CFD Research Corporation (Huntsville, Alabama)
INVENTOR(S)	Kapil Pant (Huntsville, Alabama); Shivshankar Sundaram (Goleta, California); Yi Wang (Madison, Alabama)
ABSTRACT	An electrostatic aerosol concentrator includes an airflow chamber with alternately energized and grounded electrode elements that work in concert to impart radial inward motion to charged aerosol particles and focusing them toward an enriched aerosol outlet. Aerosol particles entering the airflow chamber may carry a positive or negative charge naturally, or a charge may be induced on the particles using a charging section located upstream of the aerosol inlet. Natural or induced charges on the aerosol particles may be used to selectively concentrate subpopulations of aerosol particles from a mixture of particles. For example, bacterial spores or aerosolized viruses may be selectively enriched without concentrating other aerosol particles.
FILED	Tuesday, July 31, 2007
APPL NO	11/831613
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Gas separation: Processes 095/58
VIEW PATENT	@ USPTO: Full Text PDF

08246791 — Multi-stage column distillation (MSCD) method for osmotic solute recovery

US 08246791	McGinnis et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Robert L. McGinnis (Cambridge, Massachusetts); Menachem Elimelech (Woodbridge, Connecticut)
ABSTRACT	A method and apparatus for separating draw solution solutes and product solvent from a draw solution using a plurality of distillation columns is disclosed. In one embodiment, the draw solution is used in a Forward Osmosis (FO) water desalination process. In this embodiment, the draw solution is directed to the plurality of distillation columns in parallel while the energy stream (heat) is directed to the plurality of distillation columns in series such that the efficiency of heat use is improved and in turn the cost of the heat is reduced.
FILED	Thursday, June 07, 2007
APPL NO	12/308041
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Distillation: Processes, separatory 23/25
VIEW PATENT	@ USPTO: Full Text PDF

08246825 — Horizontal filter stage with simultaneous venting and draining

US 08246825	Walgren et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S)	Hamilton Sundstrand Corporation (Windsor Locks, Connecticut)
INVENTOR(S)	Timothy P. Walgren (Rockford, Illinois); Paul E. Honkanen (Williams Bay, Wisconsin)
ABSTRACT	A filter assembly for filtering particulate contaminants from a fluid comprises: a generally cylindrical filter unit with one end closed and the other end open; a filter head comprising a generally cylindrical sleeve extending generally horizontally an open end for receiving the open end of the filter unit with that has a vent port aligned with a vertical axis through an upper portion of the sleeve and a drain port aligned with the vertical axis extending through a lower portion of the sleeve; and a coupling for securing the open end of the filter unit to the filter head to seal the sleeve vent and drain ports; wherein loosening the coupling allows the filter unit to slide away from the filter head sufficiently to establish fluid communication between the sleeve vent and drain ports.
FILED	Monday, July 21, 2008
APPL NO	12/176459
ART UNIT	1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Liquid purification or separation 210/248
VIEW PATENT	@ USPTO: Full Text PDF

08246886 — Chemically-assisted alignment of nanotubes within extensible structures

US 08246886	Lashmore et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Natick Soldier Systems Center (NSSC)
APPLICANT(S)
ASSIGNEE(S)	Nanocomp Technologies, Inc. (Concord, New Hampshire)
INVENTOR(S)	David S. Lashmore (Lebanon, New Hampshire); Robert Braden (Pembroke, New Hampshire); Anastasios John Hart (Ann Arbor, Michigan); John Welch (Pembroke, New Hampshire)
ABSTRACT	A method and system for aligning nanotubes within an extensible structure such as a yarn or non-woven sheet. The method includes providing an extensible structure having non-aligned nanotubes, adding a chemical mixture to the extensible structure so as to wet the extensible structure, and stretching the extensible structure so as to substantially align the nanotubes within the extensible structure. The system can include opposing rollers around which an extensible structure may be wrapped, mechanisms to rotate the rollers independently or away from one another as they rotate to stretch the extensible structure, and a reservoir from which a chemical mixture may be dispensed to wet the extensible structure to help in the stretching process.
FILED	Wednesday, July 09, 2008
APPL NO	12/170092
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Plastic and nonmetallic article shaping or treating: Processes 264/289.600
VIEW PATENT	@ USPTO: Full Text PDF

08246911 — Optical amplification of molecular interactions using liquid crystals

US 08246911	Abbott et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Nicholas L. Abbott (Madison, Wisconsin); Justin J. Skaife (Lafayette, California); Vinay K. Gupta (Tampa, Florida); Timothy B. Dubrovsky (Flemington, New Jersey); Rahul Shah (Woodburg, Minnesota)
ABSTRACT	Interactions between molecules that are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides for a method for detecting an analyte, comprising contacting with said analyte a recognition moiety for said analyte, wherein said contacting causes at least a portion of a plurality of mesogens proximate to said recognition moiety to detectably switch from a first orientation to a second orientation upon contacting said analyte with said recognition moiety; and detecting said second orientation of said at least a portion of said plurality of mesogens, whereby said analyte is detected.
FILED	Wednesday, January 09, 2002
APPL NO	10/044899
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50
VIEW PATENT	@ USPTO: Full Text PDF

08246933 — Aerosol method for nano silver-silica composite anti-microbial agent

US 08246933	Jiang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Multidisciplinary University Research Initiative (MURI) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Xingmao Jiang (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico); Yong Lin (Albuquerque, New Mexico); Yung-Sung Cheng (Albuquerque, New Mexico)
ABSTRACT	A method of forming and resulting nano-structured composite includes atomizing a mixture of an amount of each of aminopropyltriethoxysilane, AgNO₃, DI water, and ethanol in a carrier gas; heating the atomized droplets at a selected temperature for a time sufficient to reduce the Ag to its elemental form in a silica matrix; and outputting the nano structured composite particles. A predetermined heating time is from about 0.01 to about 40 seconds and a selected heating temperature is from about 200 to about 800° C. The nano structured composite includes a plurality of nano particles at a contact surface of the composite, dispersed throughout and at a contact surface of the composite, or dispersed throughout the composite.
FILED	Wednesday, November 26, 2008
APPL NO	12/324318
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/46
VIEW PATENT	@ USPTO: Full Text PDF

08247032 — Methods utilizing scanning probe microscope tips and products therefor or produced thereby

US 08247032	Mirkin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Chad A. Mirkin (Wilmette, Illinois); Richard Piner (St. Louis, Missouri); Seunghun Hong (Chicago, Illinois)
ABSTRACT	The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). The method include the following steps: (i) providing a substrate and a scanning probe microscope tip; (ii) coating the tip with a patterning compound and a solvent to form a wet tip; and (iii) contacting the coated tip with the substrate so that the compound is applied to the substrate so as to produce a desired pattern. The invention also provides substrates patterned by DPN and kits for performing DPN.
FILED	Wednesday, October 31, 2007
APPL NO	11/933275
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/256
VIEW PATENT	@ USPTO: Full Text PDF

08247120 — Fuel cell system including a fuel module

US 08247120	Crumm et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S)	Adaptive Materials, Inc. (Ann Arbor, Michigan)
INVENTOR(S)	Aaron T. Crumm (Ann Arbor, Michigan); John Muczynski (Ypsilanti, Michigan); Mike Gorski (Ann Arbor, Michigan); Nathan Ernst (Ann Arbor, Michigan); Jason Krajcovic (Ann Arbor, Michigan)
ABSTRACT	A fuel cell system includes an energy conversion module and a fuel module that is detachable from the energy conversion module. The fuel module includes a fuel tank, a fuel module identification member including fuel module data and a fuel filter member. The control module is configured to access the fuel module data from the fuel module identification member. The fuel cell stack is configured to utilize the refined fuel to generate electrical energy.
FILED	Wednesday, April 22, 2009
APPL NO	12/428165
ART UNIT	2894 — Semiconductors/Memory
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/428
VIEW PATENT	@ USPTO: Full Text PDF

08247135 — Light-weight, flexible edge collected fuel cells

US 08247135	Wainright et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Jesse S. Wainright (Willoughby Hills, Ohio); Laurie A. Dudik (South Euclid, Ohio); Chung-Chiun Liu (Cleveland Heights, Ohio)
ABSTRACT	The invention is a flexible, micro-fabricated fuel cell and fuel cell stack that can be helically wound or bend into cylindrical shapes. The electrolyte is a proton exchange membrane (PEM) upon which can be printed, by ink jet means, the anode and cathode electrodes and the current collectors that convey current to or from the edges of the PEM which has a thickness on the order of 0.001 to 0.010 inch. Pluralities of the series connected fuel cell stacks can be arranged in electrical and physical parallel with one another to provide what are batteries of fuel cell stacks that can be connected by manifolds to sources of fuel and oxidizer. The invention is directed to a thin, light-weight, flexible fuel cell assembly that can be produced in ambient conditions using standard micro-fabrication techniques, such as thick film printing and ink jet deposition. Thick film printing techniques, screen printing or ink jet printing, are used to deposit porous current collectors on either side of the membrane.
FILED	Wednesday, September 14, 2005
APPL NO	11/226139
ART UNIT	1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/517
VIEW PATENT	@ USPTO: Full Text PDF

08247226 — Methods of evaluating an immune response to an antigen

US 08247226	Sukumar et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) Department of the Interior (DOI)
APPLICANT(S)
ASSIGNEE(S)	Sanofi Pasteur Vaxdesign Corp. (Orlando, Florida)
INVENTOR(S)	Selva Sukumar (Berkeley, California); Mohey Eldin M. El Shikh (Richmond, Virginia); John G. Tew (Mechanicsville, Virginia); Guzman Sanchez-Schmitz (Orlando, Florida); Donald Drake, III (Orlando, Florida); Luis Mosquera (Oviedo, Florida); Conan Li (Los Altos, California); Anatoly M. Kachurin (Orlando, Florida); Russell Higbee (Orlando, Florida); Heather Fahlenkamp (Cleveland, Oklahoma); Eric Mishkin (Winter Springs, Florida); William L. Warren (Orlando, Florida)
ABSTRACT	The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
FILED	Thursday, June 23, 2011
APPL NO	13/167115
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/375
VIEW PATENT	@ USPTO: Full Text PDF

08247238 — Device and methods of detection of airborne agents

US 08247238	Meinhart et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Carl D. Meinhart (Santa Barbara, California); Brian Piorek (Santa Barbara, California); Seung Joon Lee (Santa Barbara, California); Martin Moskovits (Santa Barbara, California); Sanjoy Banerjee (Santa Barbara, California); Juan Santiago (Stanford, California)
ABSTRACT	Provided are methods, devices and systems that utilize free-surface fluidics and SERS for analyte detection with high sensitivity and specificity. The molecules can be airborne agents, including but not limited to explosives, narcotics, hazardous chemicals, or other chemical species. The free-surface fluidic architecture is created using an open microchannel, and exhibits a large surface to volume ratio. The free-surface fluidic interface can filter interferent molecules, while concentrating airborne analyte molecules. The microchannel flow enables controlled aggregation of SERS-active probe particles in the flow, thereby enhancing the detector's sensitivity.
FILED	Thursday, August 25, 2011
APPL NO	13/217616
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/168
VIEW PATENT	@ USPTO: Full Text PDF

08247333 — Multifunctional periodic cellular solids and the method of making thereof

US 08247333	Sypeck et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	David J. Sypeck (Daytona Beach Shores, Florida); Haydn N. G. Wadley (Keswick, Virginia)
ABSTRACT	A cellular material that can provide a unique combination of properties and characteristics for a variety of applications requiring a cellular solid that possesses one or more of the following characteristics: (1) efficient load support in one or more directions, (2) excellent mechanical impact energy absorption and vibration suppression potential, (3) high convection heat transfer throughout, (4) low pumping requirements for fluid throughput, for example in a second direction orthogonal to one or more load-bearing directions, (5) a substantially linear dependence of the Young's and shear moduli along with the tensile, compressive and shear yield strengths upon relative density (6) a potentially inexpensive textile-based synthetic approach, (7) excellent filtration potential, (8) a high surface area to volume ratio for enhanced activity as a catalyst or catalyst support (9) interconnected, open porosity for device storage, biological tissue in-growth or other functionalities requiring open space, and (10) extendibility to a wide variety of materials.
FILED	Tuesday, May 29, 2001
APPL NO	10/296728
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Fabric 442/32
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08247533 — Beta helical peptide structures stable in aqueous and non-aqueous media

US 08247533	Kulp, III et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	John L. Kulp, III (Alexandria, Virginia); Thomas D. Clark (Alexandria, Virginia)
ABSTRACT	Disclosed are peptide structures that are stable in aqueous and non-aqueous media where a first linear peptide chain comprising alternating D,L- or L,D-amino acids having an N and C termini is joined by at least one turn region to a second linear peptide chain comprising alternating D,L- or L,D-amino acids having an N and C termini. The peptide chains can be joined at the C terminus of one of the linear peptide chains with an N terminus of the other linear peptide chain, a C terminus of one of the linear peptide chains with a C terminus of the other linear peptide chain, or an N terminus of one of the linear peptide chains with an N terminus of the other linear peptide chain.
FILED	Tuesday, March 06, 2012
APPL NO	13/412868
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/333
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08247586 — Methods of making layered mixed-metal phosphonates for high dielectric strength polymer nanocomposites

US 08247586	Barber, III et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Arthur Peter Barber, III (West Columbia, South Carolina); Harry J. Ploehn (Columbia, South Carolina); Hans-Conrad zur Loye (Columbia, South Carolina)
ABSTRACT	Multi-metal phosphonates are generally provided. The multi-metal phosphonate can generally have the composition: AB(RPO₃)₃, where A is Mg²⁺, Ca²⁺, Sr²⁺, Ba²⁺, Pb²⁺, La³⁺, or combinations thereof; B is Ti⁴⁺, Zr⁴⁺, Al³⁻, or combinations thereof; and R is an organic group (e.g., aryl group, an alkyl group, an alkenyl group, etc.). The multi-metal phosphonate can be combined with a polymeric material to form a polymeric film. Methods of making the multi-metal phosphonate by combining and reacting a metal oxide and an organophosphonic acid are also provided.
FILED	Monday, December 19, 2011
APPL NO	13/329731
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Organic compounds 556/19
VIEW PATENT	@ USPTO: Full Text PDF

08247632 — Process for the conversion of renewable oils to liquid transportation fuels

US 08247632	Strege et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Construction Engineering Research Laboratory (CERL) U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC) Construction Engineering Research Laboratory (CERL)
APPLICANT(S)
ASSIGNEE(S)	Energy and Environmental Research Center Foundation (Grand Forks, North Dakota)
INVENTOR(S)	Joshua R. Strege (Grand Forks, North Dakota); Benjamin G. Oster (Thompson, North Dakota); Paul D. Pansegrau (Grand Forks, North Dakota); Chad A. Wocken (Grand Forks, North Dakota); Ted R. Aulich (Grand Forks, North Dakota); Marc Kurz (Thompson, North Dakota)
ABSTRACT	A method of producing a hydrocarbon product by hydrotreating a feedstock comprising triacylglyceride (TAG) and TAG-derived materials such as free fatty acid (FFA) and fatty acid methyl ester (FAME) in the presence of a nonsulfided hydrotreating catalyst to produce a first product comprising hydrocarbons. A method of producing a transportation fuel by selecting an undoped feedstock comprising virgin TAG, used TAG, FFA, and FAME or a combination thereof; hydrotreating the undoped feedstock in the presence of an unsulfided hydrotreating catalyst to produce a first product and subjecting the first product to at least one process selected from aromatization, cyclization, and isomerization to produce a second hydrocarbon product selected from gasoline, kerosene, jet fuel, and diesel fuels. A method is described by which fatty acids may be converted to hydrocarbons suitable for use as liquid transportation fuels. Additionally, the method allows for the blending of fatty acids with TAGs, and the conversion of such blends to hydrocarbons suitable for use as liquid transportation fuels. The method utilizes a catalyst and hydrogen as reductant to convert fatty acids to hydrocarbons. Subsequent steps, including dewatering, isomerization, and distillation, can provide a hydrocarbon mixture useful as a liquid transportation fuel or as a blendstock with petroleum transportation fuels.
FILED	Saturday, June 27, 2009
APPL NO	12/493193
ART UNIT	1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry of hydrocarbon compounds 585/733
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08247729 — Electrical discharge pocketing using loop type machining electrode

US 08247729	Bichsel
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S)	Steven L. Bichsel (Arlington, Texas)
ABSTRACT	An electrode for EDM.
FILED	Wednesday, May 21, 2008
APPL NO	12/124815
ART UNIT	3742 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Electric heating 219/69.170
VIEW PATENT	@ USPTO: Full Text PDF

08247746 — Connector for heater

US 08247746	Alexander et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	Phillip Emerson Alexander (Colchester, Connecticut); David R. Lyders (Middletown, Connecticut); John Vontell (Manchester, Connecticut); George Alan Salisbury (East Hampton, Connecticut)
ABSTRACT	A connector for incorporation into a heater system for inlet struts includes a body having a tapered forward end and an opposite rear end. A plurality of forward electrical terminals are formed on the outer surface of the tapered end. A plurality of rearward electrical terminals are formed on the rear end of the body. The rearward electrical terminals are in electrical connection with the forward electrical terminals. The forward electrical terminals on the tapered end are in electrical contact with a plurality of electrical contacts connected to heating elements formed in a heating mat. The heating mat entirely envelops the connector. The heater mat is formed within a substantially rigid outer shell.
FILED	Monday, October 26, 2009
APPL NO	12/605652
ART UNIT	3742 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Electric heating 219/541
VIEW PATENT	@ USPTO: Full Text PDF

08247756 — Bi-directional data and signal channels in optical interconnects

US 08247756	Veitch et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)
ASSIGNEE(S)	Wavefront Research, Inc. (Bethlehem, Pennsylvania)
INVENTOR(S)	Randall C. Veitch (Nazareth, Pennsylvania); Thomas W. Stone (Hellertown, Pennsylvania)
ABSTRACT	In one embodiment, the present teachings provide for an efficient means to implement bidirectional data and signal channels in optical interconnects. Each optical interconnect channel may include two pairs of emitters and detectors that are imaged onto each other. Many such bidirectional optical channels may be simultaneously interconnected in dense two-dimensional arrays. The send or receive state of each bidirectional optical channel may be directly set in some embodiments by an electronic control signal. In other bidirectional optical channel embodiments, the send/receive state may be controlled locally and autonomously as derived from the output of the local detector.
FILED	Wednesday, June 03, 2009
APPL NO	12/477729
ART UNIT	2878 — Optics
CURRENT CPC	Radiant energy 250/227.110
VIEW PATENT	@ USPTO: Full Text PDF

08247769 — Characterization of nanoscale structures using an ultrafast electron microscope

US 08247769	Zewail
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Ahmed H. Zewail (Pasadena, California)
ABSTRACT	The present invention relates to methods and systems for 4D ultrafast electron microscopy (UEM)—in situ imaging with ultrafast time resolution in TEM. Single electron imaging is used as a component of the 4D UEM technique to provide high spatial and temporal resolution unavailable using conventional techniques. Other embodiments of the present invention relate to methods and systems for convergent beam UEM, focusing the electron beams onto the specimen to measure structural characteristics in three dimensions as a function of time. Additionally, embodiments provide not only 4D imaging of specimens, but characterization of electron energy, performing time resolved electron energy loss spectroscopy (EELS).
FILED	Wednesday, October 07, 2009
APPL NO	12/575312
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/311
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08247883 — Printing shielded connections and circuits

US 08247883	Daniel et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S)	Jurgen H. Daniel (San Francisco, California); Tse Nga Ng (Palo Alto, California)
ABSTRACT	An embodiment is a method and apparatus to construct a shielded cable, wire, or circuit. A first insulator layer is deposited on a first conductor or semiconductor layer. A second conductor or semiconductor layer is deposited on the first insulator layer. A second insulator layer is deposited on the first insulator layer. The second insulator layer covers the second conductor or semiconductor layer and defines a shielded region. A third conductor or semiconductor layer is deposited on the first conductor or semiconductor layer. The third conductor or semiconductor layer covers the first and second insulator layers. At least one of the first, second, and third conductor or semiconductor layers, and the first and second insulator layers is deposited by printing.
FILED	Thursday, December 04, 2008
APPL NO	12/328694
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/508
VIEW PATENT	@ USPTO: Full Text PDF

08247946 — Electrochemical actuator

US 08247946	Chiang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Yet-Ming Chiang (Framingham, Massachusetts); Michael J. Cima (Winchester, Massachusetts); Timothy E. Chin (Cambridge, Massachusetts)
ABSTRACT	The present invention provides systems, devices, and related methods, involving electrochemical actuation. In some cases, application of a voltage or current to a system or device of the invention may generate a volumetric or dimensional change, which may produce mechanical work. For example, at least a portion of the system may be constructed and arranged to be displaced from a first orientation to a second orientation. Systems such as these may be useful in various applications, including pumps (e.g., infusion pumps) and drug delivery devices, for example.
FILED	Friday, August 20, 2010
APPL NO	12/860771
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electrical generator or motor structure 310/311
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08248074 — Detection of faults in an injector arrangement

US 08248074	Perryman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S)	Delphi Technologies Holding S.arl (Troy, Michigan)
INVENTOR(S)	Louisa J. Perryman (Rainham, United Kingdom); Daniel Jeremy Hopley (Chislehurst, United Kingdom)
ABSTRACT	A fault detection method is provided for detecting faults in an injector arrangement. The injector arrangement includes one or more piezoelectric fuel injectors connected in an injector drive circuit, and the injector drive circuit is arranged to control operation of the one or more piezoelectric fuel injectors. The fault detection method includes determining a sample voltage at a sample point in the injector drive circuit at a first sample time. The sample voltage is the voltage on an injector or is related to the voltage on an injector. The method further includes calculating a range of predicted voltages expected at the sample point at a second sample time following the first sample time, and determining the sample voltage at the sample point at the second sample time. The presence of a fault is detected if the sample voltage determined at the sample point at the second sample time is not within the range of predicted voltages.
FILED	Friday, October 10, 2008
APPL NO	12/287724
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/379
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08248178 — High power waveguide polarizer with broad bandwidth and low loss, and methods of making and using same

US 08248178	Lange
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Mark J. Lange (Malibu, California)
ABSTRACT	Embodiments of the invention provide high power waveguide polarizers with broad bandwidth and low loss, and methods of making and using the same. Under one aspect of the present invention, a waveguide polarizer includes a hollow waveguide body having an interior surface; a first ridge disposed on the interior surface of the hollow waveguide body and having an inward-facing surface; and a first plurality of projections disposed on the inward-facing surface of the first ridge. The projections may have a width that is narrower than that of the ridge, and a length that is tunable. The length of the projections may be selected to induce about a 90-degree phase delay in a first mode propagating in a plane parallel to the first ridge relative to a second mode propagating in a plane perpendicular to the first ridge.
FILED	Thursday, December 03, 2009
APPL NO	12/630593
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Wave transmission lines and networks 333/21.A00
VIEW PATENT	@ USPTO: Full Text PDF

08248317 — System for physical simulation of long-distance and directional wireless channels

US 08248317	Meagher et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Christopher J. Meagher (San Diego, California); Randall B. Olsen (Carlsbad, California); Christopher C Cirullo (San Diego, California)
ABSTRACT	A system includes a first radio frequency (RF) lens having array ports and beam ports, and a second RF lens having array ports and beam ports. At least two of the second RF lens array ports are connected to at least two of the first RF lens array ports by phase-matched connectors. The RF lenses may be continuously steerable RF lenses, Rotman lenses, or discretely steerable RF lenses. The system may include first, second, third, and fourth RF switches, at least one transmitter with an associated controller, at least one receiver with associated controller, and an environment controller. The system may also include long-distance simulators connected between the RF switches of the directional simulator and the receiver or the transmitter and controlled by an environment controller. Other system embodiments include multi-pair RF lenses, as well as an RF lens connected to an antenna array system.
FILED	Tuesday, May 05, 2009
APPL NO	12/435936
ART UNIT	2821 — Semiconductors/Memory
CURRENT CPC	Communications: Radio wave antennas 343/754
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08249101 — Mobile ad hoc network configured as a virtual internet protocol network

US 08249101	Crain, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Gary W. Crain, Jr. (Palm Harbor, Florida); Michael L. Mullins (Riverview, Florida); Theodore B. Wesson (Largo, Florida)
ABSTRACT	According to one embodiment, a method for facilitating communication of a MANET is provided. A MANET may include a plurality of nodes configured as a virtual IP network. The virtual IP network may comprise a plurality of physical paths of the MANET. The physical paths may couple an IP network to an IP node. Each physical path may traverse a distinct set of nodes of the MANET. The physical paths may be represented to the IP network as a logical path comprising one or more virtual IP nodes.
FILED	Friday, March 26, 2010
APPL NO	12/732382
ART UNIT	2476 — Multiplex and VoIP
CURRENT CPC	Multiplex communications 370/466
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08249121 — Push-pull modulated coupled vertical-cavity surface-emitting lasers and method

US 08249121	Brenner et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	Vixar, Inc. (Plymouth, Minnesota)
INVENTOR(S)	Mary K. Brenner (Plymouth, Minnesota); Klein L. Johnson (Orono, Minnesota)
ABSTRACT	A laser system having separately electrically operable cavities for emitting modulated narrow linewidth light with first, second and third mirror structures separated by a first active region between the first and the second and by a second active region between the second and the third. The second mirror structure has twenty of more periods of mirror pairs.
FILED	Friday, June 17, 2011
APPL NO	13/163434
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Coherent light generators 372/46.10
VIEW PATENT	@ USPTO: Full Text PDF

08249315 — System and method for improved viewing and navigation of digital images

US 08249315	Adams et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)	UPMC (Pittsburgh, Pennsylvania)
INVENTOR(S)	Brian Adams (Greensburg, Pennsylvania); Jonhan Ho (Pittsburgh, Pennsylvania); Christine Henderson (Pittsburgh, Pennsylvania)
ABSTRACT	A system and method for improved viewing and navigation of large digital images, such as whole slide images used in microscopy. The system and method displays the digital image along with movable navigation and field of view boxes that enable a viewer to pan the digital image in an accurate manner, and also performs automatic absolute reorientation of the digital image and automatic relative reorientation of subsequent digital images in relation to the first digital image.
FILED	Tuesday, May 22, 2007
APPL NO	11/751784
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/128
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08249346 — Three dimensional imaging method and apparatus

US 08249346	Dammann
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	John F. Dammann (Chevy Chase, Maryland)
ABSTRACT	Three-dimensional imaging techniques are used for a visualization method and apparatus. In a preferred embodiment, terrain data is displayed as a series of pixels—areas of terrain elevation data. Individual pixels are analyzed to determine whether they are locally smooth or “warpable” relative to their surrounding neighbor pixels. Those pixels that are locally relatively “smooth,” i.e., those satisfying a given set of criteria, are joined with adjacent neighbor pixels by a process referred to herein as “warping” to create “smooth,” gap-free surfaces. A preferred embodiment includes drawing or generating lines between the centers of two pairs of adjacent pixels to determine a slopes m₁and m₂respectively. The slopes m₁and m₂are then analyzed using the following equations/determinations: \|m₁∥≦m_max; \|m₂∥≦m_max; and \|m₁−m₂\|≦Δmax; i.e., the slopes m₁and m₂must each be less than or equal to a predetermined threshold m_maxand the difference between the slopes must be less than or equal to a predetermined difference Δmax.
FILED	Tuesday, January 27, 2009
APPL NO	12/360757
ART UNIT	2624 — Selective Visual Display Systems
CURRENT CPC	Image analysis 382/173
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08249540 — Two stage radio frequency interference cancellation system and method

US 08249540	Gupta et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S)	Hypres, Inc. (Elmsford, New York)
INVENTOR(S)	Deepnarayan Gupta (Hawthorne, New York); Amol Inamdar (Elmsford, New York)
ABSTRACT	A radio frequency receiver subject to a large in-band interferor employs active cancellation with coarse and fine cancellation signals, each with a respective radio frequency combiner, in order to increase the effective dynamic range of the receiver for weak signals of interest. One or both can be digitally synthesized. This is particularly applicable for co-site interference, whereby the interfering transmit signal is directly accessible. A similar system and method may also be applied to external interferors such as those produced by deliberate or unintentional jamming signals, or by strong multipath signals. An adaptive algorithm may be used for dynamic delay and gain matching. In a preferred embodiment, a hybrid technology hybrid temperature system incorporates both superconducting and semiconducting components to achieve enhanced broadband performance.
FILED	Wednesday, August 05, 2009
APPL NO	12/535843
ART UNIT	2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Telecommunications 455/296
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08249820 — Detector assembly for use in environments containing background magnetic noise and method thereof

US 08249820	Edelstein
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Alan S. Edelstein (Alexandria, Virginia)
ABSTRACT	A method and system for detecting a signal source at a specified frequency in the presence of background noise includes a processor; a first sensor mounted at a first location operatively connected to the processor; a second sensor mounted at a second location operatively connected to the processor; the processor operating to compute the amplitudes of the first and second Fourier transforms of the outputs of the first and second sensors, respectively, the difference in the amplitudes of the first and second Fourier transforms being determinative of the existence of a signal being generated at the predetermined frequency.
FILED	Friday, July 02, 2010
APPL NO	12/829712
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/77
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08249838 — Method and apparatus for modeling memristor devices

US 08249838	Pino et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Robinson E. Pino (Rome, New York); James W. Bohl (Rome, New York)
ABSTRACT	A method and apparatus for modeling the characteristics of memristor devices. The invention provides methods and an apparatus for accurately characterizing the linear and non-linear Lissajous current-voltage behavior of actual memristor devices and incorporating such behavior into the resultant model. The invention produces a model that is adaptable to large scale memristor device simulations.
FILED	Wednesday, January 06, 2010
APPL NO	12/657262
ART UNIT	2128 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Structural design, modeling, simulation, and emulation 73/2
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08249846 — Automated simulation fabric discovery and configuration

US 08249846	Brown et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Aaron Ches Brown (Austin, Texas); Jeff Jerome Frankeny (Austin, Texas); James Kai Hsu (Austin, Texas); Glenn Owen Kincaid (Austin, Texas)
ABSTRACT	A configuration manager identifies a first device and a second device within a simulated system. Each device within the simulated system includes an inbound port and an outbound port. Next, the configuration manager injects a simulation only packet on the first device's outbound port and detects that the second device's inbound port receives the simulation only packet. As a result, the configuration manager determines that a direct connection exists between the first device's outbound port and the second device's inbound port. In turn, the configuration manager configures one or more first device configuration registers and one or more second device configuration registers that correspond to the first device and the second device, respectively.
FILED	Thursday, March 12, 2009
APPL NO	12/402650
ART UNIT	2128 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Structural design, modeling, simulation, and emulation 73/13
VIEW PATENT	@ USPTO: Full Text PDF

08249856 — Machine translation

US 08249856	Shen et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	RAYTHEON BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S)	Libin Shen (Needham, Massachusetts); Jinxi Xu (Framingham, Massachusetts); Ralph M. Weischedel (Canton, Massachusetts)
ABSTRACT	A method for computer-assisted translation from a source language to a target language makes use of number of rules. Each rule forms an association between a representation of a sequence of source language tokens with a corresponding tree-based structure in the target language. The tree-based structure for each of at least some of the rules represents one or more asymmetrical relations within a number of target tokens associated with the tree-based structure and provides an association of the target tokens with the sequence of source language tokens of the rule. An input sequence of source tokens is decoded according to the rules to generate a representation of one or more output sequences of target language tokens. Decoding includes, for each of at least some sub-sequences of the input sequence of source tokens, determining a tree-based structure associated with the sub-sequence according a match to one of the plurality of rules.
FILED	Thursday, March 20, 2008
APPL NO	12/052555
ART UNIT	2626 — Selective Visual Display Systems
CURRENT CPC	Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/2
VIEW PATENT	@ USPTO: Full Text PDF

08250010 — Electronic learning synapse with spike-timing dependent plasticity using unipolar memory-switching elements

US 08250010	Modha et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Dharmendra Shantilal Modha (San Jose, California); Rohit Sudhir Shenoy (Fremont, California)
ABSTRACT	According to embodiments of the invention, a system, method and computer program product producing spike-dependent plasticity in an artificial synapse. In an embodiment, a method includes: receiving a pre-synaptic spike in an electronic component; receiving a post-synaptic spike in the electronic component; in response to the pre-synaptic spike, generating a pre-synaptic pulse that occurs a predetermined period of time after the received pre-synaptic spike; in response to the post-synaptic spike, generating a post-synaptic pulse that starts at a baseline value and reaches a first voltage value a first period of time after the post-synaptic spike, followed by a second voltage value a second period of time after the post synaptic spike, followed by a return to the baseline voltage a third period of time after the post-synaptic spike; applying the generated pre-synaptic pulse to a pre-synaptic node of a synaptic device that includes a uni-polar, two-terminal bi-stable device in series with a rectifying element; and applying the generated post-synaptic pulse to a post-synaptic node of the synaptic device, wherein the synaptic device changes from a first conductive state to a second conductive state based on the value of input voltage applied to its pre and post-synaptic nodes, wherein the resultant state of the conductance of the synaptic device after the pre- and post-synaptic pulses are applied thereto depends on the relative timing of the received pre-synaptic spike with respect to the post synaptic spike.
FILED	Thursday, May 21, 2009
APPL NO	12/470403
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Artificial intelligence 76/25
VIEW PATENT	@ USPTO: Full Text PDF

08250022 — Type 5 knowledge amplification by structured expert randomization (KASER)

US 08250022	Rubin
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Stuart Harvey Rubin (San Diego, California)
ABSTRACT	A new production generation method comprising: a.) storing a list of productions on a memory store on a computer, wherein each production comprises a context and a consequent, each context and consequent comprising at least one feature; b.) searching the production list for productions with contexts that match a user-provided context; and c.) if no context-matching production is found, i.) randomly selecting a sub-set of features from the user-provided context, ii.) selecting from the production list by uniform chance a first production with a context that matches the selected feature sub-set, iii.) substituting the feature or feature sub-set with the consequent of the first production to create a first feature set, iv.) replacing features in the first feature set as specified by predefined rules to create a new feature set, and v.) displaying a new production consisting of the user-provided context and the new feature set.
FILED	Tuesday, January 05, 2010
APPL NO	12/652215
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Artificial intelligence 76/60
VIEW PATENT	@ USPTO: Full Text PDF

08250055 — Non-linear dynamical search engine

US 08250055	Ditto et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida); Control Dynamics, Inc. (Bellevue, Washington)
INVENTOR(S)	William L. Ditto (Gainesville, Florida); Sudeshna Sinha (Velachery, India); Abraham Miliotis (Gainesville, Florida)
ABSTRACT	A dynamical search engine for searching a database is also provided. The dynamical search engine includes an array of nonlinear dynamical elements. The nonlinear dynamical element information items in a manner that confines the state of each element on a fixed point and uniquely encodes the information items. The dynamical search engine also includes a controller for controlling electrical signals supplied to elements of the array in a predetermined sequence. One supplied signal increases a state value of each element of the array by a quantity defining a search key that corresponds to a searched-for information item. A subsequently supplied signal updates the state value of each element of the array by performing a nonlinear folding of each state value based on a predetermined pivot.
FILED	Wednesday, December 05, 2007
APPL NO	12/517959
ART UNIT	2825 — Semiconductors/Memory
CURRENT CPC	Data processing: Database and file management or data structures 77/706
VIEW PATENT	@ USPTO: Full Text PDF

08250140 — Enabling connections for use with a network

US 08250140	Bent et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Graham A Bent (Southampton, United Kingdom); Flavio A Bergamaschi (Southampton, United Kingdom); Patrick Dantressangle (Chandlers Ford, United Kingdom); Christopher Gibson (Southampton, United Kingdom)
ABSTRACT	An apparatus for enabling connections for use with a network comprising at least one vertex, the apparatus comprising: a receiver, for receiving a first message associated with the first vertex, wherein the first message comprises an indication that the first vertex wishes to join the network; a generator, responsive to receipt of the first message, for generating a second message associated with the at least one vertex, wherein the second message comprising an indication that the at least one vertex is operable to connect to the first vertex; and a probabilistic component for determining a first time value associated with transmission of the second message to the first vertex in accordance with probabilistic data.
FILED	Friday, April 11, 2008
APPL NO	12/101220
ART UNIT	2441 — Computer Networks
CURRENT CPC	Electrical computers and digital processing systems: Multicomputer data transferring 79/204
VIEW PATENT	@ USPTO: Full Text PDF

08250307 — Sourcing differing amounts of prefetch data in response to data prefetch requests

US 08250307	Arimilli et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Ravi K. Arimilli (Austin, Texas); Gheorghe C. Cascaval (Carmel, New York); Balaram Sinharoy (Poughkeepsie, New York); William E. Speight (Austin, Texas); Lixin Zhang (Austin, Texas)
ABSTRACT	According to a method of data processing, a memory controller receives a prefetch load request from a processor core of a data processing system. The prefetch load request specifies a requested line of data. In response to receipt of the prefetch load request, the memory controller determines by reference to a stream of demand requests how much data is to be supplied to the processor core in response to the prefetch load request. In response to the memory controller determining to provide less than all of the requested line of data, the memory controller provides less than all of the requested line of data to the processor core.
FILED	Friday, February 01, 2008
APPL NO	12/024165
ART UNIT	2188 — Computer Networks
CURRENT CPC	Electrical computers and digital processing systems: Memory 711/137
VIEW PATENT	@ USPTO: Full Text PDF

08250395 — Dynamic voltage and frequency scaling (DVFS) control for simultaneous multi-threading (SMT) processors

US 08250395	Carter et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	John B. Carter (Austin, Texas); Heather L. Hanson (Austin, Texas); Karthick Rajamani (Austin, Texas); Freeman L. Rawson, III (Austin, Texas); Todd J. Rosedahl (Zumbrota, Minnesota); Malcolm S. Ware (Austin, Texas)
ABSTRACT	A mechanism is provided for controlling operational parameters associated with a plurality of processors. A control system in the data processing system determines a utilization slack value of the data processing system. The utilization slack value is determined using one or more active core count values and one or more slack core count values. The control system computes a new utilization metric to be a difference between a full utilization value and the utilization slack value. The control system determines whether the new utilization metric is below a predetermined utilization threshold. Responsive to the new utilization metric being below the predetermined utilization threshold, the control system decreases a frequency of the plurality of processors.
FILED	Thursday, November 12, 2009
APPL NO	12/616833
ART UNIT	2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electrical computers and digital processing systems: Support 713/322
VIEW PATENT	@ USPTO: Full Text PDF

08250396 — Hardware wake-and-go mechanism for a data processing system

US 08250396	Arimilli et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas)
ABSTRACT	A hardware wake-and-go mechanism is provided for a data processing system. The wake-and-go mechanism recognizes a programming idiom that indicates that a thread is waiting for an event. The wake-and-go mechanism updates a wake-and-go array with a target address associated with the event. The thread then goes to sleep until the event occurs. The wake-and-go array may be a content addressable memory (CAM). When a transaction appears on the symmetric multiprocessing (SMP) fabric that modifies the value at a target address in the CAM, the CAM returns a list of storage addresses at which the target address is stored. The wake-and-go mechanism associates these storage addresses with the threads waiting for an even at the target addresses, and may wake the one or more threads waiting for the event.
FILED	Friday, February 01, 2008
APPL NO	12/024595
ART UNIT	2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electrical computers and digital processing systems: Support 713/323
VIEW PATENT	@ USPTO: Full Text PDF

Department of Health and Human Services (HHS)

08246550 — Comprehensive integrated testing protocol for infant lung function

US 08246550	Morris
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S)	Board of Trustees of the University of Arkansas (Little Rock, Arkansas); Arkansas Children's Hospital Research Institute, Inc. (Little Rock, Arkansas)
INVENTOR(S)	Mohy G. Morris (Little Rock, Arkansas)
ABSTRACT	A Comprehensive Integrated Testing Protocol (CITP) incorporates precise measurements of the dynamic and the static lung volumes and capacities at V₃₀for routine infant lung function testing. The static functional residual capacity (sFRC) in infants is measured after a short hyperventilation induces a post-hyperventilation apnea (PHA) that abolishes the infant's breathing strategies and creates a reliable volume landmark. A measurement of the sFRC is then obtained by inert gas washout; e.g., by measuring the volume of nitrogen expired after end-passive expiratory switching of the inspired gas from room air to 100% oxygen during the PHA. A true measurement of the total lung capacity (TLC) is obtained from the sum of (1) the passively exhaled gas volume from a Pao plateau of 30 cm H₂O through a pneumotachometer (PNT) by integrating the flow signal to produce volume, which is the inspiratory capacity (IC), and (2) the sFRC. From intrasubject TLC and residual volume (RV), the difference is a reliable estimate of the slow vital capacity (SVC). Similar measurements may be obtained with a fastened squeeze jacket for comparison. Actual airway opening pressure (aPao) is measured during a 0.20 s airway occlusion after halting the inflating airflow and prior to activating the jacket inflation. An open mouth is maintained during forced expiration in order to generate an oronasal instead of a forced expiration.
FILED	Thursday, November 15, 2007
APPL NO	11/985416
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/538
VIEW PATENT	@ USPTO: Full Text PDF

08246917 — Self-assembled, micropatterned, and radio frequency (RF) shielded biocontainers and their uses for remote spatially controlled chemical delivery

US 08246917	Gracias et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	David H. Gracias (Baltimore, Maryland); Timothy Gar-Ming Leong (Alexandria, Virginia); Hongke Ye (Woburn, Massachusetts)
ABSTRACT	The present invention relates to a nanoscale or microscale particle for encapsulation and delivery of materials or substances, including, but not limited to, cells, drugs, tissue, gels and polymers contained within the particle, with subsequent release of the therapeutic materials in situ, methods of fabricating the particle by folding a 2D precursor into the 3D particle, and the use of the particle in in-vivo or in-vitro applications The particle can be in any polyhedral shape and its surfaces can have either no perforations or nano/microscale perforations The particle is coated with a biocompatible metal, e g gold, or polymer e g parvlene, layer and the surfaces and hinges of the particle are made of any metal or polymer combinations.
FILED	Monday, June 25, 2007
APPL NO	12/306423
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/547
VIEW PATENT	@ USPTO: Full Text PDF

08246945 — Methods and reagents for decreasing clinical reaction to allergy

US 08246945	Caplan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Arkansas (Little Rock, Arkansas); Mount Sinai School of Medicine of New York University (New York, New York); Allertein Therapeutics, LLC (Fairfield, Connecticut)
INVENTOR(S)	Michael J. Caplan (Woodbridge, Connecticut); H. Kim Bottomly (Wellesley, Massachusetts); Howard B. Sosin (Fairfield, Connecticut); A. Wesley Burks (Chapel Hill, North Carolina); Hugh A. Sampson (Larchmont, New York)
ABSTRACT	The present invention provides methods and compositions for treating or preventing allergic reactions, particularly anaphylactic reactions. Methods of the present invention involve administering microorganisms to allergic subjects, where the microorganisms contain a recombinant version of the protein allergen. The recombinant version can be wild-type or may include mutations within IgE epitopes of the protein allergen. Preferably the compositions are administered rectally. Particularly preferred microorganisms are bacteria such as E. coli. Any allergen may be used in the inventive methods. Particularly preferred allergens are anaphylactic allergens including protein allergens found in foods, venoms, drugs and latex. The inventive compositions and methods are demonstrated in the treatment of peanut-induced anaphylaxis.
FILED	Friday, October 02, 2009
APPL NO	12/572599
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/93.200
VIEW PATENT	@ USPTO: Full Text PDF

08246957 — Lupus antibodies for passive immunotherapy of HIV/AIDS

US 08246957	Paul
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S)	Sudhir Paul (Missouri City, Texas)
ABSTRACT	Disclosed are monoclonal antibodies and antibody fragments which recognize antigens encoded by HERV DNA sequences, and methods for production, including recombinant antibody fragments derived from lymphoid cells of lupus patients that make antibodies which neutralize HIV.
FILED	Monday, March 29, 2004
APPL NO	10/581295
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/148.100
VIEW PATENT	@ USPTO: Full Text PDF

08246959 — Dendritic cell-associated lectin-like molecules, compositions and methods of use

US 08246959	Clark et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Edward A. Clark (Seattle, Washington); Elizabeth Ryan (Cappawhite, Ireland); Aaron Marshall (Winnipeg, Canada); Kevin Draves (Seattle, Washington)
ABSTRACT	The invention provides novel dendritic cell-associated lectin-like (DCAL-1) molecules, compositions and therapeutic methods of use. In one aspect, the invention provides isolated nucleic acid molecules that are capable of remaining hybridized to SEQ ID NO:1 or SEQ ID NO:3, including nucleic acid molecules that encode DCAL-1 polypeptides. In another aspect, the invention provides DCAL-1 polypeptides and portions thereof which are useful to stimulate T cell proliferation. In another aspect, the invention provides antibodies that specifically bind to DCAL-1 which are useful for promoting maturation of dendritic cells and for stimulating an immune response in vivo. In another aspect the invention provides methods of stimulating an immune response in an animal comprising introducing into the animal an anti-DCAL-1 antibody of the invention.
FILED	Friday, January 05, 2007
APPL NO	11/620582
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/173.100
VIEW PATENT	@ USPTO: Full Text PDF

08246966 — Trypanosome microsome system and uses thereof

US 08246966	Mensa-Wilmot
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S)	Kojo Mensa-Wilmot (Watkinsville, Georgia)
ABSTRACT	The present invention provides cell free preparations of protozoan microsomes, wherein the cell free preparation of protozoan microsomes demonstrate the ability to translocate a protozoan polypeptide into the microsome, methods of preparing cell free preparations of protozoan microsomes, and methods of using cell free preparations of protozoan microsomes.
FILED	Friday, February 06, 2009
APPL NO	12/367093
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/269.100
VIEW PATENT	@ USPTO: Full Text PDF

08246983 — Encapsulated arsenic drugs

US 08246983	O'Halloran et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evarston, Illinois)
INVENTOR(S)	Thomas O'Halloran (Chicago, Illinois); Haimei Chen (Evanston, Illinois)
ABSTRACT	The present invention relates to methods and compositions for the treatment of cancer and for research and analysis of cancer. In particular, the present invention provides encapsulated arsenic anti-cancer compositions with improved properties.
FILED	Tuesday, September 05, 2006
APPL NO	11/515711
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/450
VIEW PATENT	@ USPTO: Full Text PDF

08246995 — Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells

US 08246995	Dai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Hongjie Dai (Cupertino, California); Nadine Wong Shi Kam (Stanford, California); Paul A. Wender (Menlo Park, California); Zhuang Liu (Stanford, California)
ABSTRACT	Methods and materials for delivering biologically active molecules to cells in vitro or in vivo are provided. The methods and materials use carbon nanotubes or other hydrophobic particles, tubes and wires, functionalized with a linking group that is covalently bound to the nanotubes, or, alternatively, to the biologically active molecule, such as a protein. The biologically active molecule is preferably released from the nanotube when the complex has been taken up in an endosome.
FILED	Tuesday, May 09, 2006
APPL NO	11/431346
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/489
VIEW PATENT	@ USPTO: Full Text PDF

08247168 — Regulation of gene expression by protein methylation

US 08247168	Stallcup et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	University of Southern California (Los Angeles, California); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Michael R. Stallcup (Los Angeles, California); Dagang Chen (Hacienda Heights, California); Heng Hong (Carmel, Indiana); Dana W. Aswad (Irvine, California)
ABSTRACT	The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate gene expression in vivo. CARM1 has also been used to methylate arginine residues of histones, synthetic peptides, and other proteins. A method to use CARM1 to screen for drugs that inhibit its methyltransferase activity is also described, as is a method to screen for drugs that modulate CARM1's interactions with other proteins.
FILED	Friday, October 02, 2009
APPL NO	12/573066
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6
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08247173 — Spinocerebellar ataxia type 8 and methods of detection

US 08247173	Ranum et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Regents of the University of Minnesota (St. Paul, Minnesota)
INVENTOR(S)	Laura P. W. Ranum (St. Paul, Minnesota); Michael D. Koob (Roseville, Minnesota); Kellie A. Benzow (Plymouth, Minnesota); Melinda L. Moseley-Alldredge (St. Paul, Minnesota)
ABSTRACT	The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
FILED	Monday, June 21, 2010
APPL NO	12/819749
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
VIEW PATENT	@ USPTO: Full Text PDF

08247174 — Methods of diagnosing endometriosis

US 08247174	Giudice
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Linda C. Giudice (Los Altos Hills, California)
ABSTRACT	The present invention provides biomarkers for the diagnosis and prognosis of endometriosis. Generally, the methods of this invention find use in diagnosing or for providing a prognosis for endometriosis by detecting the expression levels of biomarkers, which are differentially expressed (up- or down-regulated) in endometrial cells from a patient with endometriosis. Similarly, these markers can be used to diagnose reduced fertility in a patient with endometriosis or to provide a prognosis for a fertility trial in a patient suffering from endometriosis. The present invention also provides methods of identifying a compound for treating or preventing endometriosis. Finally, the present invention provides kits for the diagnosis or prognosis of endometriosis.
FILED	Thursday, December 16, 2010
APPL NO	12/970576
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
VIEW PATENT	@ USPTO: Full Text PDF

08247181 — Borrelia diagnostics and screening methods

US 08247181	Barbour et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Library of Medicine (NLM) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Experimental and Integrative Activities (EIA)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Alan G. Barbour (Newport Beach, California); Philip L. Felgner (Rancho Sante Fe, California)
ABSTRACT	Compositions and methods of detecting Borrelia proteins, nucleic acid sequences encoding these proteins, and subject antibodies to these proteins in a sample are disclosed.
FILED	Monday, September 08, 2008
APPL NO	12/676794
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.100
VIEW PATENT	@ USPTO: Full Text PDF

08247186 — Monoclonal antibodies and their use

US 08247186	Grompe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S)	Oregon Health and Science University (Portland, Oregon)
INVENTOR(S)	Markus Grompe (Portland, Oregon); Philip R. Streeter (Portland, Oregon); Craig Dorrell (Portland, Oregon); Stephanie L. Abraham (Clancy, Montana); Kelsea M. Shoop (Oregon City, Oregon)
ABSTRACT	Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof. Isolated monoclonal antibodies are also disclosed herein that specifically bind a cell surface antigen expressed on human pancreatic exocrine cells or human ductal cells. Humanized forms of these antibodies, and functional fragments of these antibodies, are also disclosed. The antibodies can be conjugated to an effector molecule, or a detectable marker. These antibodies are of use to detect and/or isolate pancreatic cells or a subset thereof. Methods of treating a pancreatic tumor are also disclosed.
FILED	Tuesday, December 13, 2011
APPL NO	13/324929
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.210
VIEW PATENT	@ USPTO: Full Text PDF

08247190 — Method for delivering cytotoxic activity to cells

US 08247190	Raines et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Ronald T. Raines (Madison, Wisconsin); Julie C. Mitchell (Madison, Wisconsin); Thomas J. Rutkoski (Madison, Wisconsin)
ABSTRACT	This invention relates to altered forms of members of the RNase A superfamily. An RNase A can be modified to be cytotoxic by altering its amino acid sequence so that it is not bound easily by the ribonuclease inhibitor while still retaining catalytic properties. While earlier work had identified some modifications to RNase A that would result in cytotoxicity, the use of the FADE algorithm for molecular interaction analysis has led to several other locations that were candidates for modification. Some of those modifications did result in RNase A variants with increase cytotoxicity.
FILED	Monday, July 11, 2011
APPL NO	13/180359
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/19
VIEW PATENT	@ USPTO: Full Text PDF

08247195 — Methods and host cells for recombinant protein expression

US 08247195	Fang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)	The University of Washington (Seattle, Washington)
INVENTOR(S)	Ferric C. Fang (Mercer Island, Washington); William Wiley Navarre (Toronto, Canada); Stephen J. Libby (Issaquah, Washington)
ABSTRACT	Methods for expressing recombinant polypeptides in host cells and host cells for polypeptide expression are provided.
FILED	Wednesday, January 16, 2008
APPL NO	12/015443
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/69.600
VIEW PATENT	@ USPTO: Full Text PDF

08247198 — Enzymatic processing in deep eutectic solvents

US 08247198	Gorke et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Friedrich Srienc (St. Paul, Minnesota)
INVENTOR(S)	Johnathan T. Gorke (St. Paul, Minnesota); Romas J. Kazlauskas (Falcon Heights, Minnesota); Friedrich Srienc (Lake Elmo, Minnesota)
ABSTRACT	It has surprisingly been discovered that it is possible to use enzymes in deep eutectic solvents (DES). DES's are mixtures of a nitrogen salt or a metal salt and a strong hydrogen bond donor that can be mixed in proportions that form a eutectic point.
FILED	Monday, September 22, 2008
APPL NO	12/284466
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/129
VIEW PATENT	@ USPTO: Full Text PDF

08247225 — DNA promoters and anthrax vaccines

US 08247225	Kopecko et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Dennis J. Kopecko (Silver Spring, Maryland); Manuel Osorio (Bethesda, Maryland); Siba Bhattacharyya (Bethesda, Maryland); Milan Blake (Fulton, Maryland)
ABSTRACT	The invention is related to intracellularly induced bacterial DNA promoters and vaccines against Bacillus anthracis.
FILED	Tuesday, June 08, 2010
APPL NO	12/796410
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/320.100
VIEW PATENT	@ USPTO: Full Text PDF

08247227 — Dendritic cell precursors

US 08247227	Cohen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S)	The Cleveland Clinic Foundation (Cleveland, Ohio); Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); National Institutes of Health (Rockville, Maryland)
INVENTOR(S)	Peter A. Cohen (Chagrin Falls, Ohio); Suyu Shu (Shaker Heights, Ohio); Gary K. Koski (Akron, Ohio); Charles S. Carter (Rockville, Maryland); Laura Carter, legal representative (Rockville, Maryland); Brian J. Czerniecki (Haddonfield, New Jersey)
ABSTRACT	A method of generating a population of dendritic cell (DC) precursors includes obtaining a population of progenitor cells from a subject and culturing the progenitor cells in a culture medium. The culture medium can include Flt3 ligand and interleukin-6 and be free of granulocyte-macrophage colony-stimulating factor.
FILED	Tuesday, August 28, 2007
APPL NO	11/845976
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/377
VIEW PATENT	@ USPTO: Full Text PDF

08247228 — Method of inducing memory B cell development and terminal differentiation

US 08247228	Ettinger et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Catherine Rachel Ettinger (Bethesda, Maryland); Peter E. Lipsky (Rockville, Maryland); Warren J. Leonard (Bethesda, Maryland); Rosanne Spolski (Ellicott City, Maryland); Herbert C. Morse, III (Rockville, Maryland)
ABSTRACT	The invention provides a method for promoting differentiation of a mature naïve B cell or a B cell progenitor into a memory B cell or a plasma cell. The method comprises (a) contacting a population of cells comprising a mature naïve B cell or a B cell progenitor with an agent that activates at least one of JAK1, JAK3, STAT3, STAT5A or STAT5B; wherein the population of cells optionally is contacted with an antigen, and (b) isolating the memory B cell or plasma cell.
FILED	Friday, May 23, 2008
APPL NO	12/126166
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/377
VIEW PATENT	@ USPTO: Full Text PDF

08247229 — Method of differentiating stem cells into cells of the endoderm and pancreatic lineage

US 08247229	Odorico et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Jon Odorico (Fitchburg, Wisconsin); Xiaofang Xu (Madison, Wisconsin)
ABSTRACT	Methods are described to more efficiently produce cells of the endoderm and pancreatic lineage from mammalian pluripotent stem cells. These methods provide a simple, reproducible culture protocol using defined media components to enable consistent, large-scale production of pancreatic cell types for research or therapeutic uses.
FILED	Monday, June 28, 2010
APPL NO	12/825281
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/377
VIEW PATENT	@ USPTO: Full Text PDF

08247352 — Method of inhibiting ethylene production in plants

US 08247352	Thrower et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Julie Thrower (Silver Spring, Maryland); Judith Klinman (Berkeley, California)
ABSTRACT	Methods of inhibiting ethylene production in a plant are provided that involve contacting a plant or plant part with an inhibitor of 1-aminocyclopropane-1-carboxylic acid oxidase (ACCO). The methods can be used to delay fruit and vegetable ripening, flower opening, or senescence of cut flowers. Also described are kits including an ACCO inhibitor and a floral preservative.
FILED	Friday, March 10, 2006
APPL NO	11/885915
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Plant protecting and regulating compositions 54/235
VIEW PATENT	@ USPTO: Full Text PDF

08247374 — Methods and compositions for the repair and/or regeneration of damaged myocardium using cytokines and variants thereof

US 08247374	Anversa
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute on Aging (NIA)
APPLICANT(S)
ASSIGNEE(S)	New York Medical College (Valhalla, New York)
INVENTOR(S)	Piero Anversa (Boston, Massachusetts)
ABSTRACT	Methods, compositions, and kits for repairing damaged myocardium and/or myocardial cells including the administration of cytokines, variants of cytokines, cardiac stem cells, or combinations thereof are disclosed and claimed. In addition, methods, compositions, and kits for forming coronary vasculature including the administration of cytokines, variants of cytokines, cardiac stem cells, or combinations thereof are described. In particular, administration of variants of hepatocyte growth factor, such as NK1, 1K1, and HP11, are useful for the repair and/or regeneration of damaged myocardium or formation of coronary vasculature. Methods of activating cardiac stem cells in vitro are also disclosed.
FILED	Monday, November 10, 2008
APPL NO	12/267849
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/9.500
VIEW PATENT	@ USPTO: Full Text PDF

08247376 — NGAL for reduction and amelioration of ischemic and nephrotoxic injuries

US 08247376	Barasch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Columbia University (New York, New York); Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S)	Jonathan M. Barasch (New York, New York); Prasad Devarajan (Cincinnati, Ohio); Kiyoshi Mori (New York, New York)
ABSTRACT	Use of neutrophil gelatinase-associated lipocalin (NGAL) as a therapeutic and in a method of treating, reducing, or ameliorating an injury selected from an ischemic injury, an ischemic-reperfusion injury, and a toxin-induced injury, to an organ in a patient. The invention includes administering to the patient NGAL in an amount effective to treat, reduce or ameliorate ischemic, ischemic-reperfusion, or toxin-induced injury to the organ, such as the kidney. A siderophore can be co-administered with the NGAL. The invention also relates to administering a sideophore to enhance a response to secretion of NGAL following an ischemic or toxin-induced injury to an organ in a patient.
FILED	Thursday, June 17, 2010
APPL NO	12/817566
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/15.400
VIEW PATENT	@ USPTO: Full Text PDF

08247388 — Role of miRNA in T cell leukemia

US 08247388	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Chang-Zheng Chen (Stanford, California); Tin Mao (Alameda, California)
ABSTRACT	The ability of miR-181a to support active signaling between Notch and pre-TCR pathways by coordinately dampening negative regulators of these pathways allows the use of miR-181a as a therapeutic target for T-ALL.
FILED	Monday, June 08, 2009
APPL NO	12/455898
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44
VIEW PATENT	@ USPTO: Full Text PDF

08247399 — Photoactive metal nitrosyls for blood pressure regulation and cancer therapy

US 08247399	Mascharak
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Pradip K. Mascharak (Santa Cruz, California)
ABSTRACT	Disclosed are nitric oxide delivery agents and methods of their use, more specifically to photoactive compounds, which are able to perform targeted delivery of nitric oxide in vitro and in vivo and are useful for medicinal applications including, but not limited, to blood pressure regulation and cancer treatment.
FILED	Thursday, March 03, 2011
APPL NO	13/039794
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/185
VIEW PATENT	@ USPTO: Full Text PDF

08247427 — Dual phase drug release system

US 08247427	Papisov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Mikhail I. Papisov (Winchester, Massachusetts); Alexander Yurkovetskiy (Littleton, Massachusetts)
ABSTRACT	The present invention relates to conjugate comprising a carrier substituted with one or more occurrences of a moiety having the structure: wherein each occurrence of M is independently a modifier having a molecular weight ≦10 kDa; denotes direct of indirect attachment of M to linker L^M; and each occurrence of L^Mis independently an optionally substituted succinamide-containing linker, whereby the modifier M is directly or indirectly attached to the succinamide linker through an amide bond, and the carrier is linked directly or indirectly to each occurrence of the succinamide linker through an ester bond. In another aspect, the invention provides compositions comprising the conjugates, methods for their preparation, and methods of use thereof in the treatment of various disorder, including, but not limited to cancer.
FILED	Friday, June 03, 2011
APPL NO	13/152790
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/283
VIEW PATENT	@ USPTO: Full Text PDF

08247438 — Methods for treating schizophrenia

US 08247438	Elkashef
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)
ASSIGNEE(S)	Neuropill, Inc. (Dunn Loring, Virginia)
INVENTOR(S)	Ahmed Elkashef (Dunn Loring, Virginia)
ABSTRACT	Treatment of schizophrenia or humans suffering from conditions associated with high dopamine levels in ventral striatum or caudate nucleus administers the compound (2S)-2-{3-[3-({[(2R,4R)-4-tert-Butoxycarbonyl-2-(2-fluorophenyl)]-3-thiazolidinyl}carbonylmethyl)ureido]phenyl}propionic acid and its physiological acceptable salts.
FILED	Tuesday, June 10, 2008
APPL NO	12/136099
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/365
VIEW PATENT	@ USPTO: Full Text PDF

08247443 — Small molecule antagonists of bacterial quorum-sensing receptors

US 08247443	Bassler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Bonnie L. Bassler (Princeton, New Jersey); Lee R. Swem (Lawrenceville, New Jersey); Scott M. Ulrich (Ithaca, New York); Colleen T. O'Loughlin (Princeton, New Jersey)
ABSTRACT	A novel small molecule antagonizes two types of acyl homoserine lactone receptors: membrane-bound and cytoplasmic. A focused library of analogs and derivatives of the original antagonist was synthesized. Analog and derivative molecules harbor a range of activities. The novel small molecule and most potent antagonist protects the eukaryote Caenorhabditis elegans from quorum-sensing-mediated killing by the bacterial pathogen Chromobacterium violaceum. The saving of C. elegans demonstrates the use of these molecules as small molecule antimicrobials.
FILED	Monday, December 21, 2009
APPL NO	12/643574
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/445
VIEW PATENT	@ USPTO: Full Text PDF

08247457 — Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy

US 08247457	Fahl et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	William E. Fahl (Madison, Wisconsin); Arnold E. Ruoho (Madison, Wisconsin); Minesh Mehta (Sun Prairie, Wisconsin)
ABSTRACT	Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages and formulations of topical vasoconstrictors are provided. Methods for the use of such compositions are also provided.
FILED	Thursday, May 12, 2011
APPL NO	13/106293
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/653
VIEW PATENT	@ USPTO: Full Text PDF

08247531 — Mutant epidermal growth factor polypeptides, nucleic acids, and uses therefor

US 08247531	Cochran et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S)	Jennifer R. Cochran (Stanford, California); K. Dane Wittrup (Chestnut Hill, Massachusetts)
ABSTRACT	The present invention is based, in part, on our discovery that EGF can be engineered to generate mutants that bind to the EGF receptor (EGFR) of a cell and that have a desirable effect on the activity of the cell. For example, the mutants can agonize the receptor (i.e., increase a biological activity of the receptor), or antagonize the receptor (i.e., decrease or inhibit a biological activity of the receptor). In turn, the rate at which the cell proliferates, for example, can be changed. Moreover, some of these mutants bind EGFR with a higher affinity than wild-type EGF exhibits. The affinity may increase by about, for example, 2-, 5-, 10-, 15-, 20-, 25-, 30-, 50-, or 100-fold relative to wild-type EGF.
FILED	Tuesday, March 20, 2007
APPL NO	11/725695
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324
VIEW PATENT	@ USPTO: Full Text PDF

08247543 — Human microRNAs and methods for inhibiting same

US 08247543	Tuschl et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	The Rockefeller University (New York, New York)
INVENTOR(S)	Thomas Tuschl (Brooklyn, New York); Pablo Landgraf (Duesseldorf, Germany)
ABSTRACT	The invention relates to isolated DNA or RNA molecules comprising at least ten contiguous bases having a sequence in a microRNA shown in SEQ ID NOs: 1-94; 281-374; 467-481; 497-522; or 549, except that up to thirty percent of the bases may be wobble bases, and up to 10% of the contiguous bases may be non-complementary. The invention further relates to modified single stranded microRNA molecules, isolated single stranded anti-microRNA molecules and isolated microRNP molecules. In another embodiment, the invention relates to a method for inhibiting microRNP activity in a cell.
FILED	Monday, May 01, 2006
APPL NO	11/919393
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/24.500
VIEW PATENT	@ USPTO: Full Text PDF

08247551 — Lead sensor and methods of use

US 08247551	Basu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S)	Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania)
INVENTOR(S)	Partha Basu (Pittsburgh, Pennsylvania); Barbara Serli Mitasev (Melrose, Massachusetts); Lauren E. Marbella (Pittsburgh, Pennsylvania)
ABSTRACT	A fluorophore that forms a complex with Pb ions is disclosed. The fluorophore/lead complex fluoresces with an intensity greater than complexes formed by the fluorophore with other metals. The fluorophore may be used as a sensor/detector for lead ions in various samples. Methods for detecting and calculating the concentration of lead ions in samples are also disclosed.
FILED	Tuesday, August 18, 2009
APPL NO	12/583294
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Organic compounds 544/343
VIEW PATENT	@ USPTO: Full Text PDF

08247613 — Methods and compositions for the synergistic activation of latent HIV

US 08247613	Williams et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S)	The J. David Gladstone Institutes (San Francisco, California)
INVENTOR(S)	Samuel A. F. Williams (San Mateo, California); Warner C. Greene (Hillsborough, California)
ABSTRACT	The present invention provides methods and compositions useful for the elimination of latent HIV reservoirs that persist despite HAART. The methods and compositions overcome this latent barrier by inducing the replication of HIV in latently infected T cells while preventing the spread of the newly produced virions to uninfected cells by providing HAART simultaneously. Compositions of the invention comprise an activator of latent HIV expression, such as prostratin, and an inhibitor of histone deacetylase, such as TSA. A surprising finding of this invention is that the inhibitor of the histone deacetylase synergizes the effect of prostratin thus, allowing administering to a patient a lower, non-toxic dose of prostratin.
FILED	Tuesday, April 17, 2007
APPL NO	12/297034
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Organic compounds 568/347
VIEW PATENT	@ USPTO: Full Text PDF

08247769 — Characterization of nanoscale structures using an ultrafast electron microscope

US 08247769	Zewail
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Ahmed H. Zewail (Pasadena, California)
ABSTRACT	The present invention relates to methods and systems for 4D ultrafast electron microscopy (UEM)—in situ imaging with ultrafast time resolution in TEM. Single electron imaging is used as a component of the 4D UEM technique to provide high spatial and temporal resolution unavailable using conventional techniques. Other embodiments of the present invention relate to methods and systems for convergent beam UEM, focusing the electron beams onto the specimen to measure structural characteristics in three dimensions as a function of time. Additionally, embodiments provide not only 4D imaging of specimens, but characterization of electron energy, performing time resolved electron energy loss spectroscopy (EELS).
FILED	Wednesday, October 07, 2009
APPL NO	12/575312
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/311
VIEW PATENT	@ USPTO: Full Text PDF

08248071 — Methods of using combined forward and backward sampling of nuclear magnetic resonance time domain for measurement of secondary phase shifts, detection of absorption mode signals devoid of dispersive components, and/or optimization of nuclear magnetic resonance experiments

US 08248071	Szyperski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S)	Thomas Szyperski (Amherst, New York); Arindam Ghosh (North Tonawanda, New York); Yibing Wu (Snyder, New York)
ABSTRACT	The present invention relates to a method of conducting an N-dimensional nuclear magnetic resonance (NMR) experiment in a phase-sensitive manner by the use of forward and backward sampling of time domain shifted by a primary phase shift under conditions effective to measure time domain amplitudes and secondary phase shifts. The present invention also relates to methods of conducting an N-dimensional NMR experiment in a phase-sensitive manner by the use of dual forward and backward sampling of time domain shifted by a primary phase shift under conditions effective to measure secondary phase shifts or at least partially cancel dispersive and quadrature image signal components arising in the frequency domain from secondary phase shifts.
FILED	Thursday, February 12, 2009
APPL NO	12/370303
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/309
VIEW PATENT	@ USPTO: Full Text PDF

08248462 — Dynamic parallax barrier autosteroscopic display system and method

US 08248462	Peterka et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Thomas Peterka (Hillside, Illinois); Daniel Sandin (Chicago, Illinois)
ABSTRACT	Embodiments of the invention provide a dynamic parallax barrier autostereoscopic system and method for one and multiple users with user tracking. One example embodiment of the invention is a dynamic parallax barrier autostereoscopic virtual reality display system includes a display including a front display plane and a rear display plane. The front display plane dynamically generates barrier strips with transparent regions therebetween. The rear display plane generates images viewable through the transparent regions to create a virtual reality effect for a user or users.
FILED	Monday, April 16, 2007
APPL NO	11/787435
ART UNIT	2444 — Computer Networks
CURRENT CPC	Television 348/54
VIEW PATENT	@ USPTO: Full Text PDF

08249682 — Device for measuring concentrations of constituents of tear sample

US 08249682	Cappo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)
ASSIGNEE(S)	Lacrisciences, LLC (Washington, District of Columbia)
INVENTOR(S)	Anthony P. Cappo (New York, New York); Gregory Bennett (New York, New York); Jeffrey P Gilbard (Weston, Massachusetts); Paul T Gavaris (Bethesda, Maryland); Diptabhas Sarkar (Houston, Texas)
ABSTRACT	A medical diagnostic method utilizes a surface plasmon resonance apparatus provided with a sensing surface. A tear sample from an eye of a patient is placed into contact with the sensing surface. The surface plasmon resonance apparatus is then operated to determine concentrations of solutes such as salt and antigenic analytes in the tear sample.
FILED	Thursday, September 06, 2007
APPL NO	11/899596
ART UNIT	3777 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Surgery 6/310
VIEW PATENT	@ USPTO: Full Text PDF

08249714 — Lower extremity exercise device with stimulation and related methods

US 08249714	Hartman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S)	Customkynetics, Inc. (Versailles, Kentucky)
INVENTOR(S)	Eric Hartman (Versailles, Kentucky); James Abbas (Scottsdale, Arizona); JoAnne Resig (Lexington, Kentucky); John Alton (Lexington, Kentucky); Mark Griffin (Louisville, Kentucky); Nancy Quick (Saco, Maine)
ABSTRACT	A device and methods for performing a closed-chain exercise for the lower extremities of a human subject and, in particular, the legs, using stimulation. The device may include a sled for receiving the subject and for translating to and fro between a first, lower position in which the legs are at least partially bent and a second, higher position in which the legs are less bent than in the first position. A stimulator is provided for facilitating the performance of the closed-chain leg exercise by the subject to move the sled between the first and second positions, either by way of electrical signals provided directly to the applicable muscles or by way of sensory (e.g., visual) stimulation, with or without electro-muscular stimulation. In another aspect, adaptive feed-forward control may also be used to enhance the exercise regimen performed using the device.
FILED	Monday, July 10, 2006
APPL NO	11/483786
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/48
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

08245508 — Improving efficiency of liquid heat exchange in compressed-gas energy storage systems

US 08245508	Bollinger et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)
ASSIGNEE(S)	SustainX, Inc. (Seabrook, New Hampshire)
INVENTOR(S)	Benjamin Bollinger (Windsor, Vermont); Patrick Magari (Plainfield, New Hampshire); Troy O. McBride (Norwich, Vermont)
ABSTRACT	In various embodiments, efficiency of energy storage and recovery systems employing compressed air and liquid heat exchange is improved via control of the system operation and/or the properties of the heat-exchange liquid.
FILED	Friday, April 15, 2011
APPL NO	13/087936
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/407
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08246569 — Implantable intraocular pressure drain

US 08246569	Meng et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Ellis Fan-chuin Meng (Pasadena, California); Po-Jui Chen (Pasadena, California); Damien Rodger (Los Angeles, California); Yu-Chong Tai (Pasadena, California); Mark Humayun (Glendale, California)
ABSTRACT	An implanted parylene tube shunt relieves intra-ocular pressure. The device is implanted with an open end in the anterior chamber of the eye, allowing excess fluid to be drained through the tube out of the eye. In one embodiment, only a first end of the tube implanted into the anterior chamber of the eye is open. Intra-ocular pressure (IOP) is then monitored, for example utilizing an implanted sensor. When IOP exceeds a critical value, a practitioner intervenes, puncturing with a laser a thinned region of the tube lying outside the eye, thereby initiating drainage of fluid and relieving pressure. In accordance with alternative embodiments, the both ends of the tube are open, and the tube includes a one-way valve configured to permit drainage where IOP exceeds the critical value. The tube may include projecting barbs to anchor the tube in the eye without the need for sutures.
FILED	Tuesday, August 16, 2005
APPL NO	11/205757
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery 64/8
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08246746 — Laser uses for single-crystal CVD diamond

US 08246746	Hemley et al.
FUNDED BY	National Science Foundation (NSF) Directorate of Geosciences (GEO) Division of Earth Sciences (EAR)
APPLICANT(S)
ASSIGNEE(S)	Carnegie Institution of Washington (Washington, District of Columbia)
INVENTOR(S)	Russell J. Hemley (Washington, District of Columbia); Ho-Kwang Mao (Washington, District of Columbia); Chih-Shiue Yan (Washington, District of Columbia)
ABSTRACT	The present invention is directed to new laser-related uses for single-crystal diamonds produced by chemical vapor deposition. One such use is as a heat sink for a laser; another such use is as a frequency converter. The invention is also directed to a χ⁽³⁾nonlinear crystalline material for Raman laser converters comprising single crystal diamond.
FILED	Monday, January 28, 2008
APPL NO	12/010613
ART UNIT	1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/89
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08246802 — Small volume liquid manipulation, method, apparatus and process

US 08246802	Mezic et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Mathematical Sciences (DMS)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Igor Mezic (Goleta, California); Frederic Bottausci (Santa Barbara, California); Jason S. Spievak (Santa Barbara, California); Peter J. Strand (Santa Barbara, California)
ABSTRACT	An apparatus, a method and a process to achieve manipulation of particles and/or solutions through the use of electrokinetic properties are disclosed. The manipulation is performed using a disposable device positioned on top of a stage for purposes of powering the electrodes. The fluidic solution is brought into contact with the active part of the device and then manipulated.
FILED	Wednesday, May 14, 2008
APPL NO	12/120620
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Electrical and wave energy 24/450
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08246911 — Optical amplification of molecular interactions using liquid crystals

US 08246911	Abbott et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Nicholas L. Abbott (Madison, Wisconsin); Justin J. Skaife (Lafayette, California); Vinay K. Gupta (Tampa, Florida); Timothy B. Dubrovsky (Flemington, New Jersey); Rahul Shah (Woodburg, Minnesota)
ABSTRACT	Interactions between molecules that are components of self-assembled monolayers and other molecules can be amplified and transduced into an optical signal through the use of a mesogenic layer. The invention provides for a method for detecting an analyte, comprising contacting with said analyte a recognition moiety for said analyte, wherein said contacting causes at least a portion of a plurality of mesogens proximate to said recognition moiety to detectably switch from a first orientation to a second orientation upon contacting said analyte with said recognition moiety; and detecting said second orientation of said at least a portion of said plurality of mesogens, whereby said analyte is detected.
FILED	Wednesday, January 09, 2002
APPL NO	10/044899
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.50
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08246933 — Aerosol method for nano silver-silica composite anti-microbial agent

US 08246933	Jiang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Multidisciplinary University Research Initiative (MURI) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	STC.UNM (Albuquerque, New Mexico)
INVENTOR(S)	Xingmao Jiang (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico); Yong Lin (Albuquerque, New Mexico); Yung-Sung Cheng (Albuquerque, New Mexico)
ABSTRACT	A method of forming and resulting nano-structured composite includes atomizing a mixture of an amount of each of aminopropyltriethoxysilane, AgNO₃, DI water, and ethanol in a carrier gas; heating the atomized droplets at a selected temperature for a time sufficient to reduce the Ag to its elemental form in a silica matrix; and outputting the nano structured composite particles. A predetermined heating time is from about 0.01 to about 40 seconds and a selected heating temperature is from about 200 to about 800° C. The nano structured composite includes a plurality of nano particles at a contact surface of the composite, dispersed throughout and at a contact surface of the composite, or dispersed throughout the composite.
FILED	Wednesday, November 26, 2008
APPL NO	12/324318
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/46
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08246995 — Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells

US 08246995	Dai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Hongjie Dai (Cupertino, California); Nadine Wong Shi Kam (Stanford, California); Paul A. Wender (Menlo Park, California); Zhuang Liu (Stanford, California)
ABSTRACT	Methods and materials for delivering biologically active molecules to cells in vitro or in vivo are provided. The methods and materials use carbon nanotubes or other hydrophobic particles, tubes and wires, functionalized with a linking group that is covalently bound to the nanotubes, or, alternatively, to the biologically active molecule, such as a protein. The biologically active molecule is preferably released from the nanotube when the complex has been taken up in an endosome.
FILED	Tuesday, May 09, 2006
APPL NO	11/431346
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/489
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08246999 — Capped mesoporous silicates

US 08246999	Lin et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Victor Shang-Yi Lin (Ames, Iowa); Cheng-Yu Lai (Ames, Iowa); Srdija Jeftinija (Ames, Iowa); Dusan M. Jeftinija (Lexington, Kentucky)
ABSTRACT	The invention provides an article comprising, a mesoporous silicate matrix, such as a particle, having one or more pores; and one or more releasable caps obstructing one or more of the pores. The articles are useful as delivery vehicles for encapsulated agents such as therapeutic agents, polynucleotides, polypeptides and the like.
FILED	Thursday, March 26, 2009
APPL NO	12/411869
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/502
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08247033 — Self-assembly of block copolymers on topographically patterned polymeric substrates

US 08247033	Russell et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	The University of Massachusetts (Boston, Massachusetts); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Thomas P. Russell (Amherst, Massachusetts); Soojin Park (Amherst, Massachusetts); Dong Hyun Lee (Amherst, Massachusetts); Ting Xu (Berkeley, California)
ABSTRACT	Highly-ordered block copolymer films are prepared by a method that includes forming a polymeric replica of a topographically patterned crystalline surface, forming a block copolymer film on the topographically patterned surface of the polymeric replica, and annealing the block copolymer film. The resulting structures can be used in a variety of different applications, including the fabrication of high density data storage media. The ability to use flexible polymers to form the polymeric replica facilitates industrial-scale processes utilizing the highly-ordered block copolymer films.
FILED	Thursday, September 03, 2009
APPL NO	12/553484
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/256
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08247181 — Borrelia diagnostics and screening methods

US 08247181	Barbour et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Library of Medicine (NLM) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Experimental and Integrative Activities (EIA)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Alan G. Barbour (Newport Beach, California); Philip L. Felgner (Rancho Sante Fe, California)
ABSTRACT	Compositions and methods of detecting Borrelia proteins, nucleic acid sequences encoding these proteins, and subject antibodies to these proteins in a sample are disclosed.
FILED	Monday, September 08, 2008
APPL NO	12/676794
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.100
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08247205 — Chalcone isomerase polypeptides and crystals thereof

US 08247205	Noel et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	The Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S)	Joseph P Noel (San Diego, California); Joseph Jez (Hayward, California); Marianne E. Bowman (San Diego, California)
ABSTRACT	This disclosure provides crystalline flavonoid or flavanone isomerases, isolated non-native isomerase having the structural coordinates of said crystalline isomerase, and nucleic acids encoding such non-native isomerase. Also disclosed are methods of predicting the activity and/or substrate specificity of a putative isomerase, methods of identifying potential ismerase substrates, and methods of identifying potential isomerase inhibitors.
FILED	Friday, September 03, 2010
APPL NO	12/875952
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/233
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08247238 — Device and methods of detection of airborne agents

US 08247238	Meinhart et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Carl D. Meinhart (Santa Barbara, California); Brian Piorek (Santa Barbara, California); Seung Joon Lee (Santa Barbara, California); Martin Moskovits (Santa Barbara, California); Sanjoy Banerjee (Santa Barbara, California); Juan Santiago (Stanford, California)
ABSTRACT	Provided are methods, devices and systems that utilize free-surface fluidics and SERS for analyte detection with high sensitivity and specificity. The molecules can be airborne agents, including but not limited to explosives, narcotics, hazardous chemicals, or other chemical species. The free-surface fluidic architecture is created using an open microchannel, and exhibits a large surface to volume ratio. The free-surface fluidic interface can filter interferent molecules, while concentrating airborne analyte molecules. The microchannel flow enables controlled aggregation of SERS-active probe particles in the flow, thereby enhancing the detector's sensitivity.
FILED	Thursday, August 25, 2011
APPL NO	13/217616
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/168
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08247443 — Small molecule antagonists of bacterial quorum-sensing receptors

US 08247443	Bassler et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Bonnie L. Bassler (Princeton, New Jersey); Lee R. Swem (Lawrenceville, New Jersey); Scott M. Ulrich (Ithaca, New York); Colleen T. O'Loughlin (Princeton, New Jersey)
ABSTRACT	A novel small molecule antagonizes two types of acyl homoserine lactone receptors: membrane-bound and cytoplasmic. A focused library of analogs and derivatives of the original antagonist was synthesized. Analog and derivative molecules harbor a range of activities. The novel small molecule and most potent antagonist protects the eukaryote Caenorhabditis elegans from quorum-sensing-mediated killing by the bacterial pathogen Chromobacterium violaceum. The saving of C. elegans demonstrates the use of these molecules as small molecule antimicrobials.
FILED	Monday, December 21, 2009
APPL NO	12/643574
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/445
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08247464 — Method of selective foaming for porous polymeric material

US 08247464	Li et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Wei Li (Austin, Texas); Hai Wang (Sugar Land, Texas); Vipin Kumar (Seattle, Washington); Thomas J. Matula (Kirkland, Washington)
ABSTRACT	A selective high intensity ultrasonic foaming technique is described to fabricate porous polymers for biomedical applications. Process variables, including ultrasound power, scanning speed, and gas concentration have an affect on pore size. Pore size can be controlled with the scanning speed of the ultrasound insonation and interconnected porous structures could be obtained using a partially saturated polymers. A gas concentration range of 3-5% by weight creates interconnected open-celled porous structures. The selective high intensity ultrasonic foaming method can be used on biocompatible polymers so as not to introduce any organic solvents. The method has use in cell related biomedical applications such as studying cell growth behaviors by providing a porous environment with varying topological features.
FILED	Thursday, April 07, 2011
APPL NO	13/082133
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 521/50.500
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08247769 — Characterization of nanoscale structures using an ultrafast electron microscope

US 08247769	Zewail
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Ahmed H. Zewail (Pasadena, California)
ABSTRACT	The present invention relates to methods and systems for 4D ultrafast electron microscopy (UEM)—in situ imaging with ultrafast time resolution in TEM. Single electron imaging is used as a component of the 4D UEM technique to provide high spatial and temporal resolution unavailable using conventional techniques. Other embodiments of the present invention relate to methods and systems for convergent beam UEM, focusing the electron beams onto the specimen to measure structural characteristics in three dimensions as a function of time. Additionally, embodiments provide not only 4D imaging of specimens, but characterization of electron energy, performing time resolved electron energy loss spectroscopy (EELS).
FILED	Wednesday, October 07, 2009
APPL NO	12/575312
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/311
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08247784 — Switched ferroelectric plasma ionizer

US 08247784	Neidholdt et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Evan L. Neidholdt (Pasadena, California); Jesse L. Beauchamp (La Canada Flintridge, California)
ABSTRACT	A novel ion source for ambient mass spectrometry (switched ferroelectric plasma ionizer or “SwiFerr”), which utilizes the ambient pressure plasma resulting from a sample of barium titanate [001] whose polarization is switched by an audio frequency electric field. High yields of both anions and cations are produced by the source and detected using an ion trap mass spectrometer. Protonated amines and deprotonated volatile acid species, respectively, are detected in the observed mass spectra. Aerodynamic sampling is employed to analyze powders of drug tablets of loperamide and ibuprofen. A peak corresponding to the active pharmaceutical ingredient for each drug is observed in the mass spectra. Pyridine is detected at concentrations in the low part-per-million range in air. The low power consumption of the source is consistent with incorporation into field portable instrumentation for detection of hazardous materials and trace substances in a variety of different applications.
FILED	Thursday, July 29, 2010
APPL NO	12/845785
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/423.R00
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08248071 — Methods of using combined forward and backward sampling of nuclear magnetic resonance time domain for measurement of secondary phase shifts, detection of absorption mode signals devoid of dispersive components, and/or optimization of nuclear magnetic resonance experiments

US 08248071	Szyperski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)	The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S)	Thomas Szyperski (Amherst, New York); Arindam Ghosh (North Tonawanda, New York); Yibing Wu (Snyder, New York)
ABSTRACT	The present invention relates to a method of conducting an N-dimensional nuclear magnetic resonance (NMR) experiment in a phase-sensitive manner by the use of forward and backward sampling of time domain shifted by a primary phase shift under conditions effective to measure time domain amplitudes and secondary phase shifts. The present invention also relates to methods of conducting an N-dimensional NMR experiment in a phase-sensitive manner by the use of dual forward and backward sampling of time domain shifted by a primary phase shift under conditions effective to measure secondary phase shifts or at least partially cancel dispersive and quadrature image signal components arising in the frequency domain from secondary phase shifts.
FILED	Thursday, February 12, 2009
APPL NO	12/370303
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/309
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08248125 — RF microwave circuit and pulse shaping method

US 08248125	Maxwell et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Erick Maxwell (Lithia Springs, Georgia); Thomas Weller (Lutz, Florida); Ebenezer Odu (Brandon, Florida)
ABSTRACT	A multi-port circuit and corresponding method for simultaneous shaping of sub-nanosecond pulses (MCS³P). The MCS³P includes a coupled-line coupler, a Schottky detector diode, and circuitry for compressing the rising and falling edges of a waveform. The MCS³P simultaneously produces square wave, Gaussian, and monocycle waveforms by differentiating a sinusoidal source. The method includes the steps of compressing the rising edge of a sinusoidal source waveform, differentiating the resulting waveform to form a square waveform and a Gaussian waveform, filtering out the positive going Gaussian to produce a negative going Gaussian, differentiating the Gaussian waveform to form a monocycle waveform, and compressing the falling edge of the square waveform to produce a square wave form with both edges compressed.
FILED	Thursday, February 09, 2012
APPL NO	13/369936
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Miscellaneous active electrical nonlinear devices, circuits, and systems 327/164
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08248462 — Dynamic parallax barrier autosteroscopic display system and method

US 08248462	Peterka et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Thomas Peterka (Hillside, Illinois); Daniel Sandin (Chicago, Illinois)
ABSTRACT	Embodiments of the invention provide a dynamic parallax barrier autostereoscopic system and method for one and multiple users with user tracking. One example embodiment of the invention is a dynamic parallax barrier autostereoscopic virtual reality display system includes a display including a front display plane and a rear display plane. The front display plane dynamically generates barrier strips with transparent regions therebetween. The rear display plane generates images viewable through the transparent regions to create a virtual reality effect for a user or users.
FILED	Monday, April 16, 2007
APPL NO	11/787435
ART UNIT	2444 — Computer Networks
CURRENT CPC	Television 348/54
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08248476 — Robust stereo calibration system and method for accurate digital image correlation measurements

US 08248476	Ke et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Xiodan Ke (Columbia, South Carolina); Michael A. Sutton (Columbia, South Carolina)
ABSTRACT	A stereo calibration method is proposed to calibrate an interface's shape and position when the measurement system is in one media and measures deformation and strain of an object that is submerged in a different media. After the interface's shape and position are modeled by parameters, an explicit model of object points as measurement is established taking account of refraction happening at the interface. Efficiency and convergence are assured by using measurement of object points to acquire initial estimates for refraction angles at the interface. Then, an optimization method is performed to get the optimized value of interface parameters. Last, based on the resulting interface parameters, 3-dimensional positions of object points in all the subsequent measurement could be reconstructed accurately. Therefore, the distortion induced by refraction in the measurement is corrected. Numerical simulations of the proposed calibration process confirm that it is both robust and accurate for a range of experimental conditions, even in the presence of Gaussian noise in the measurement.
FILED	Thursday, September 03, 2009
APPL NO	12/553561
ART UNIT	2422 — Cable and Television
CURRENT CPC	Television 348/187
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08248515 — Variable imaging arrangements and methods therefor

US 08248515	Ng et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Yi-Ren Ng (San Mateo, California); Patrick M. Hanrahan (Portola Valley, California); Mark A. Horowitz (Menlo Park, California); Marc S. Levoy (Stanford, California)
ABSTRACT	Various approaches to imaging involve selecting directional and spatial resolution. According to an example embodiment, images are computed using an imaging arrangement to facilitate selective directional and spatial aspects of the detection and processing of light data. Light passed through a main lens is directed to photosensors via a plurality of microlenses. The separation between the microlenses and photosensors is set to facilitate directional and/or spatial resolution in recorded light data, and facilitating refocusing power and/or image resolution in images computed from the recorded light data. In one implementation, the separation is varied between zero and one focal length of the microlenses to respectively facilitate spatial and directional resolution (with increasing directional resolution, hence refocusing power, as the separation approaches one focal length).
FILED	Tuesday, February 06, 2007
APPL NO	12/278714
ART UNIT	2622 — Selective Visual Display Systems
CURRENT CPC	Television 348/343
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08248609 — Cylindrical illumination confocal spectroscopy system

US 08248609	Wang et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Tza-Huei Wang (Timonium, Maryland); Kelvin J. Liu (Baltimore, Maryland)
ABSTRACT	A cylindrical illumination confocal spectroscopy system has a fluidic device having a fluid channel defined therein, an objective lens unit arranged proximate the fluidic device, an illumination system in optical communication with the objective lens unit to provide light to illuminate a sample through the objective lens unit, and a detection system in optical communication with the objective lens unit to receive at least a portion of light that passes through the objective lens unit from the sample. The illumination system includes a beam-shaping lens unit constructed and arranged to provide a substantially planar illumination beam that subtends across, and is longer than, a lateral dimension of the fluid channel.
FILED	Wednesday, November 04, 2009
APPL NO	12/612300
ART UNIT	2877 — Optics
CURRENT CPC	Optics: Measuring and testing 356/402
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08248681 — Water-dispersible polyaniline films capable of undergoing stable and reversible polyelectrochromic transitions

US 08248681	Loo et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S)	Yueh-Lin Loo (Princeton, New Jersey); Joung Eun Yoo (Plainsboro, New Jersey); Jacob Tarver (Princeton, New Jersey)
ABSTRACT	The present disclosure relates generally to polyaniline (PANI) materials capable of undergoing stable and reversible polyelectrochromic transitions between multiple oxidation states. More specifically, the embodiments described herein include novel PANI-PAAMPSA structures that are capable of undergoing stable and reversible transitions between the ES, LB and PB oxidation states. In some embodiments, the structures described are capable of undergoing stable transitions over a broad pH range. Also described herein are methods of preparing certain electrochromic structures.
FILED	Tuesday, January 04, 2011
APPL NO	12/984166
ART UNIT	2872 — Optics
CURRENT CPC	Optical: Systems and elements 359/265
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08248995 — Wireless communications using frequency agile radio

US 08248995	Mark et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S)	George Mason Intellectual Properties, Inc. (Fairfax, Virginia)
INVENTOR(S)	Brian L. Mark (Fairfax, Virginia); Ahmed Omar Nasif (Fairfax, Virginia)
ABSTRACT	A frequency agile radio configured to determine an estimated coverage area of a primary transmitter is disclosed. The radio includes at least one position device configured to determine a position coordinate of the radio and generate a corresponding position signal. The radio also includes at least one frequency agile receiver configured to measure a power of a transmission at least one frequency and generate a corresponding signal. Additionally, the radio includes at least one controller in communication with the at least one position device and the at least one frequency agile receiver. The controller is configured to determine a plurality of position coordinates of the radio and a plurality of signal power datums. The controller is also configured to estimate the coverage area of the at least one primary transmitter, based on the determined plurality of position coordinates and the determined plurality of signal power datums.
FILED	Wednesday, March 11, 2009
APPL NO	12/402191
ART UNIT	2464 — Multiplex and VoIP
CURRENT CPC	Multiplex communications 370/328
VIEW PATENT	@ USPTO: Full Text PDF

08250073 — Preparing and presenting content

US 08250073	Wong
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Wee Ling Wong (Altadena, California)
ABSTRACT	Systems and techniques to prepare and present content. In general, in one implementation, a technique includes receiving information identifying a first streaming content element describing a first scope of material, receiving information identifying a second streaming content element describing a second scope of material, and describing a presentation including the first streaming content element and the second streaming content element in a parent/child relationship. The second scope of material can be more detailed than the first scope and included in the first scope.
FILED	Wednesday, April 30, 2003
APPL NO	10/427699
ART UNIT	2165 — Data Bases & File Management
CURRENT CPC	Data processing: Database and file management or data structures 77/736
VIEW PATENT	@ USPTO: Full Text PDF

08250507 — Distributing computations in a parallel processing environment

US 08250507	Agarwal et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Anant Agarwal (Weston, Massachusetts); Michelle Leger (Edgewood, New Mexico)
ABSTRACT	A system comprises a plurality of computation units interconnected by an interconnection network. A method for configuring the system comprises accepting a set of instructions corresponding to a portion of a program that performs a computation repeatedly; identifying subsets of the instructions; and associating each subset with a different one of the computation units to form a specification of the set of instructions such that execution according to the specification forms a pipeline among at least some of the computation units.
FILED	Thursday, October 21, 2010
APPL NO	12/909521
ART UNIT	2825 — Semiconductors/Memory
CURRENT CPC	Computer-aided design and analysis of circuits and semiconductor masks 716/110
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

08245430 — Method and apparatus for disrupting components of explosive devices

US 08245430	Owenby et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Rodney N. Owenby (Albuquerque, New Mexico); Larry E. Henderson (Eubank, Kentucky)
ABSTRACT	A system, a firing apparatus and method for disrupting at least one electrical component of an explosive device are provided. The system has an electrical cartridge, the firing apparatus and an initiator. The electrical cartridge has a projectile at an end thereof deployable into the electrical component(s). The firing apparatus has a barrel, a breech and an electrical contact. The barrel has a firing end aimable toward the electrical component, and a passage therein for receiving the electrical cartridge. The breech is operatively connectable to the barrel. The electrical contact is positionable in the breech in operative contact with the electrical cartridge. The electrical contact is operatively connectable to the initiator. The initiator selectively provides an electrical signal to the electrical cartridge via the electrical contact whereby the electrical cartridge may be activated to deploy the projectile from the firing end of the barrel.
FILED	Tuesday, September 29, 2009
APPL NO	12/568774
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Firearms 042/84
VIEW PATENT	@ USPTO: Full Text PDF

08245508 — Improving efficiency of liquid heat exchange in compressed-gas energy storage systems

US 08245508	Bollinger et al.
FUNDED BY	Department of Energy (DOE) Office of Electricity (DOE-OE) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)
ASSIGNEE(S)	SustainX, Inc. (Seabrook, New Hampshire)
INVENTOR(S)	Benjamin Bollinger (Windsor, Vermont); Patrick Magari (Plainfield, New Hampshire); Troy O. McBride (Norwich, Vermont)
ABSTRACT	In various embodiments, efficiency of energy storage and recovery systems employing compressed air and liquid heat exchange is improved via control of the system operation and/or the properties of the heat-exchange liquid.
FILED	Friday, April 15, 2011
APPL NO	13/087936
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/407
VIEW PATENT	@ USPTO: Full Text PDF

08245661 — Magnetic separation of devitrified particles from corrosion-resistant iron-based amorphous metal powders

US 08245661	Hailey et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California); Sandia National Laboratories (Livermore, California)
INVENTOR(S)	Phillip D. Hailey (Livermore, California); Sumner D. Day (Danville, California); Joseph C. Farmer (Tracy, California); Nancy Yang (Lafayette, California); Thomas M. Devine, Jr. (Moraga, California); Larry Kaufman (Brookline, Massachusetts)
ABSTRACT	A system for coating a surface comprising providing a source of iron-based amorphous metal, the iron-based amorphous metal including devitrified ferrite; directing the iron-based amorphous metal toward the surface by a spray for coating the surface; and separating at least a portion of the devitrified ferrite from the spray before the spray reaches the surface. Also an apparatus for coating a surface comprising a source of iron-based amorphous metal, the iron-based amorphous metal including devitrified ferrite; an application system for directing the iron-based amorphous metal toward the surface by a spray for coating the surface, and a system for separating at least a portion of the devitrified ferrite from the spray before the spray reaches the surface.
FILED	Thursday, November 09, 2006
APPL NO	11/595056
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating apparatus 118/629
VIEW PATENT	@ USPTO: Full Text PDF

08246718 — Process for separating carbon dioxide from flue gas using sweep-based membrane separation and absorption steps

US 08246718	Wijmans et al.
FUNDED BY	Department of Energy (DOE) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)	Membrane Technology and Research, Inc (Newark, California)
INVENTOR(S)	Johannes G. Wijmans (Menlo Park, California); Richard W. Baker (Palo Alto, California); Timothy C. Merkel (Menlo Park, California)
ABSTRACT	A gas separation process for treating flue gases from combustion processes, and combustion processes including such gas separation. The invention involves routing a first portion of the flue gas stream to be treated to an absorption-based carbon dioxide capture step, while simultaneously flowing a second portion of the flue gas across the feed side of a membrane, flowing a sweep gas stream, usually air, across the permeate side, then passing the permeate/sweep gas to the combustor.
FILED	Monday, September 13, 2010
APPL NO	13/123342
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Gas separation: Processes 095/51
VIEW PATENT	@ USPTO: Full Text PDF

08246719 — Use of impure inert gases in the controlled heating and cooling of mixed conducting metal oxide materials

US 08246719	Carolan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Air Products and Chemicals, Inc. (Allentown, Pennsylvania)
INVENTOR(S)	Michael Francis Carolan (Allentown, Pennsylvania); John Charles Bernhart (Fleetwood, Pennsylvania)
ABSTRACT	Method for processing an article comprising mixed conducting metal oxide material. The method comprises contacting the article with an oxygen-containing gas and either reducing the temperature of the oxygen-containing gas during a cooling period or increasing the temperature of the oxygen-containing gas during a heating period; during the cooling period, reducing the oxygen activity in the oxygen-containing gas during at least a portion of the cooling period and increasing the rate at which the temperature of the oxygen-containing gas is reduced during at least a portion of the cooling period; and during the heating period, increasing the oxygen activity in the oxygen-containing gas during at least a portion of the heating period and decreasing the rate at which the temperature of the oxygen-containing gas is increased during at least a portion of the heating period.
FILED	Friday, September 25, 2009
APPL NO	12/567167
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Gas separation: Processes 095/54
VIEW PATENT	@ USPTO: Full Text PDF

08246767 — Heat treated 9 Cr-1 Mo steel material for high temperature application

US 08246767	Jablonski et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the United States Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Paul D. Jablonski (Salem, Oregon); David Alman (Corvallis, Oregon); Omer Dogan (Corvallis, Oregon); Gordon Holcomb (Albany, Oregon); Christopher Cowen (Albany, Oregon)
ABSTRACT	The invention relates to a composition and heat treatment for a high-temperature, titanium alloyed, 9 Cr-1 Mo steel exhibiting improved creep strength and oxidation resistance at service temperatures up to 650° C. The novel combination of composition and heat treatment produces a heat treated material containing both large primary titanium carbides and small secondary titanium carbides. The primary titanium carbides contribute to creep strength while the secondary titanium carbides act to maintain a higher level of chromium in the finished steel for increased oxidation resistance, and strengthen the steel by impeding the movement of dislocations through the crystal structure. The heat treated material provides improved performance at comparable cost to commonly used high-temperature steels such as ASTM P91 and ASTM P92, and requires heat treatment consisting solely of austenization, rapid cooling, tempering, and final cooling, avoiding the need for any hot-working in the austenite temperature range.
FILED	Friday, September 12, 2008
APPL NO	12/209488
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Metal treatment 148/607
VIEW PATENT	@ USPTO: Full Text PDF

08246952 — Method of increasing radiation sensitivity by inhibition of beta one integrin

US 08246952	Park et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Catherine Park (San Francisco, California); Mina J. Bissell (Berkeley, California)
ABSTRACT	A method for increasing or monitoring apoptosis in tumor cells by the co-administration of ionizing radiation and an anti-integrin antibody. Increasing apoptosis reduces tumor growth in vivo and in a cell culture model. The antibody is directed against the beta-1 integrin subunit and is inhibitory of beta-1 integrin signaling. Other molecules having an inhibitory effect on beta-1 integrin, either in signaling or in binding to its cognate extracellular receptors may also be used. The present method is particularly of interest in treatment of tumor cells associated with breast cancer, wherein radiation is currently used alone. The present method further contemplates a monoclonal antibody suitable for human administration that may further comprise a radioisotope attached thereto.
FILED	Wednesday, October 07, 2009
APPL NO	12/575411
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/130.100
VIEW PATENT	@ USPTO: Full Text PDF

08247009 — Biological methane production from coal, manure, sludge, wastes, or other carbonaceous feedstocks with simultaneous sequestration of CO₂

US 08247009	Datta et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Rathin Datta (Chicago, Illinois); Seth W. Snyder (Lincolnwood, Illinois); Richard D. Doctor (Lisle, Illinois); Michael P. Henry (Batavia, Illinois)
ABSTRACT	The present invention provides a method for generating methane from a carbonaceous fuel source with simultaneous sequestration of carbon dioxide, the method comprising anaerobically incubating a particulate alkaline earth metal salt in contact with a particulate and/or dissolved carbonaceous feedstock in a neutral or alkaline aqueous culture medium containing a culture of methanogenic bacteria consortia and collecting methane generated therefrom. At least a portion of carbon dioxide produced during the incubation reacts with the alkaline earth metal salt to form an alkaline earth metal carbonate, thereby sequestering the carbon dioxide.
FILED	Thursday, September 24, 2009
APPL NO	12/586689
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Food or edible material: Processes, compositions, and products 426/56
VIEW PATENT	@ USPTO: Full Text PDF

08247032 — Methods utilizing scanning probe microscope tips and products therefor or produced thereby

US 08247032	Mirkin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Chad A. Mirkin (Wilmette, Illinois); Richard Piner (St. Louis, Missouri); Seunghun Hong (Chicago, Illinois)
ABSTRACT	The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). The method include the following steps: (i) providing a substrate and a scanning probe microscope tip; (ii) coating the tip with a patterning compound and a solvent to form a wet tip; and (iii) contacting the coated tip with the substrate so that the compound is applied to the substrate so as to produce a desired pattern. The invention also provides substrates patterned by DPN and kits for performing DPN.
FILED	Wednesday, October 31, 2007
APPL NO	11/933275
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/256
VIEW PATENT	@ USPTO: Full Text PDF

08247033 — Self-assembly of block copolymers on topographically patterned polymeric substrates

US 08247033	Russell et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S)	The University of Massachusetts (Boston, Massachusetts); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Thomas P. Russell (Amherst, Massachusetts); Soojin Park (Amherst, Massachusetts); Dong Hyun Lee (Amherst, Massachusetts); Ting Xu (Berkeley, California)
ABSTRACT	Highly-ordered block copolymer films are prepared by a method that includes forming a polymeric replica of a topographically patterned crystalline surface, forming a block copolymer film on the topographically patterned surface of the polymeric replica, and annealing the block copolymer film. The resulting structures can be used in a variety of different applications, including the fabrication of high density data storage media. The ability to use flexible polymers to form the polymeric replica facilitates industrial-scale processes utilizing the highly-ordered block copolymer films.
FILED	Thursday, September 03, 2009
APPL NO	12/553484
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/256
VIEW PATENT	@ USPTO: Full Text PDF

08247136 — Carbon based electrocatalysts for fuel cells

US 08247136	Yan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Yushan Yan (Riverside, California); Xin Wang (Singapore, Singapore); Wenzhen Li (Riverside, California); Mahesh Waje (Riverside, California); Zhongwei Chen (Riverside, California); William Goddard (Pasadena, California); Wei-Qiao Deng (Pasadena, California)
ABSTRACT	Novel proton exchange membrane fuel cells and direct methanol fuel cells with nanostructured components are configured with higher precious metal utilization rate at the electrodes, higher power density, and lower cost. To form a catalyst, platinum or platinum-ruthenium nanoparticles are deposited onto carbon-based materials, for example, single-walled, dual-walled, multi-walled and cup-stacked carbon nanotubes. The deposition process includes an ethylene glycol reduction method. Aligned arrays of these carbon nanomaterials are prepared by filtering the nanomaterials with ethanol. A membrane electrode assembly is formed by sandwiching the catalyst between a proton exchange membrane and a diffusion layer that form a first electrode. The second electrode may be formed using a conventional catalyst. The several layers of the MEA are hot pressed to form an integrated unit. Proton exchange membrane fuel cells and direct methanol fuel cells are developed by stacking the membrane electrode assemblies in a conventional manner.
FILED	Wednesday, March 15, 2006
APPL NO	11/376768
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/524
VIEW PATENT	@ USPTO: Full Text PDF

08247208 — Zymomonas with improved xylose utilization in stress conditions

US 08247208	Caimi et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S)	Alliance for Sustainable Energy LLC (, None); E I du Pont de Nemours and Company (Wilmington, Delaware)
INVENTOR(S)	Perry G. Caimi (Kennett Square, Pennsylvania); Mark Emptage (Wilmington, Delaware); Xu Li (Newark, Delaware); Paul V. Viitanen (West Chester, Pennsylvania); Yat-Chen Chou (Lakewood, Colorado); Mary Ann Franden (Centennial, Colorado); Min Zhang (Lakewood, Colorado)
ABSTRACT	Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.
FILED	Friday, December 18, 2009
APPL NO	12/641642
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/245
VIEW PATENT	@ USPTO: Full Text PDF

08247234 — Isotopically labeled compositions and method

US 08247234	Schmidt et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Jurgen G. Schmidt (Los Alamos, New Mexico); David B. Kimball (Los Alamos, New Mexico); Marc A. Alvarez (Santa Fe, New Mexico); Robert F. Williams (Los Alamos, New Mexico); Rudolfo A. Martinez (Santa Fe, New Mexico)
ABSTRACT	Compounds having stable isotopes ¹³C and/or ²H were synthesized from precursor compositions having solid phase supports or affinity tags.
FILED	Thursday, June 02, 2011
APPL NO	13/151755
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/56
VIEW PATENT	@ USPTO: Full Text PDF

08247243 — Solar cell interconnection

US 08247243	Sheats et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Nanosolar, Inc. (San Jose, California)
INVENTOR(S)	Jayna Sheats (Palo Alto, California); Phil Stob (Fremont, California)
ABSTRACT	Methods and devices for solar cell interconnection are provided. In one embodiment, the method includes physically alloying the ink metal to the underlying foil (hence excellent adhesion and conductivity with no pre-treatment), and by fusing the solid particles in the ink on the surface (eliminating any organic components) so that the surface is ideally suited for good conductivity and adhesion to an overlayer of finger ink, which is expected to be another adhesive. In some embodiments, contact resistance of conductive adhesives are known to be much lower on gold or silver than on any other metals.
FILED	Monday, May 24, 2010
APPL NO	12/786396
ART UNIT	2823 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Semiconductor device manufacturing: Process 438/22
VIEW PATENT	@ USPTO: Full Text PDF

08247325 — Direct growth of metal nanoplates on semiconductor substrates

US 08247325	Sun
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S)	Uchicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Yugang Sun (Naperville, Illinois)
ABSTRACT	Metal nanoplates are grown on n-type and p-type semiconductor wafer substrates through galvanic reactions between substantially pure aqueous metal solutions and the substrates. The morphology of the resulting metal nanoplates that protrude from the substrate can be tuned by controlling the concentration of the metal solution and the reaction time of the solution with the semiconductor wafer. Nanoplate size gradually increases with prolonged growth time and the nanoplate thicknesses increases in a unique stepwise fashion due to polymerization and fusion of adjacent nanoplates. Further, the roughness of the nanoplates can also be controlled. In a particular embodiment, Ag nanoplates are grown on a GaAs substrate through reaction with a solution of AgNO₃with the substrate.
FILED	Tuesday, October 06, 2009
APPL NO	12/574552
ART UNIT	2891 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/686
VIEW PATENT	@ USPTO: Full Text PDF

08247554 — Detection of electrophilic and nucleophilic chemical agents

US 08247554	McElhanon et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	James R. McElhanon (Livermore, California); Timothy J. Shepodd (Livermore, California)
ABSTRACT	A “real time” method for detecting chemical agents generally and particularly electrophilic and nucleophilic species by employing tunable, precursor sensor materials that mimic the physiological interaction of these agents to form highly florescent berberine-type alkaloids that can be easily and rapidly detected. These novel precursor sensor materials can be tuned for reaction with both electrophilic (chemical species, toxins) and nucleophilic (proteins and other biological molecules) species. By bonding or otherwise attaching these precursor molecules to a surface or substrate they can be used in numerous applications.
FILED	Friday, November 09, 2007
APPL NO	11/983500
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Organic compounds 546/90
VIEW PATENT	@ USPTO: Full Text PDF

08247767 — Particle detection and applications in security and portal monitoring

US 08247767	Morris et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Christopher L. Morris (Los Alamos, New Mexico); Mark F. Makela (Los Alamos, New Mexico)
ABSTRACT	Techniques, apparatus and systems for detecting particles such as muons. In one implementation, a monitoring system has a cosmic ray-produced charged particle tracker with a plurality of drift cells. The drift cells, which can be for example aluminum drift tubes, can be arranged at least above and below a volume to be scanned to thereby track incoming and outgoing charged particles, such as cosmic ray-produced muons, while also detecting gamma rays. The system can selectively detect devices or materials, such as iron, lead, gold and/or tungsten, occupying the volume from multiple scattering of the charged particles passing through the volume and can also detect any radioactive sources occupying the volume from gamma rays emitted therefrom. If necessary, the drift tubes can be sealed to eliminate the need for a gas handling system. The system can be employed to inspect occupied vehicles at border crossings for nuclear threat objects.
FILED	Friday, October 26, 2007
APPL NO	12/447459
ART UNIT	2884 — Optics
CURRENT CPC	Radiant energy 250/307
VIEW PATENT	@ USPTO: Full Text PDF

08247942 — Multi-winding homopolar electric machine

US 08247942	Van Neste
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S)	UT-Batelle, LLC (Oal Ridge, Tennessee)
INVENTOR(S)	Charles W. Van Neste (Kingston, Tennessee)
ABSTRACT	A multi-winding homopolar electric machine and method for converting between mechanical energy and electrical energy. The electric machine includes a shaft defining an axis of rotation, first and second magnets, a shielding portion, and a conductor. First and second magnets are coaxial with the shaft and include a charged pole surface and an oppositely charged pole surface, the charged pole surfaces facing one another to form a repulsive field therebetween. The shield portion extends between the magnets to confine at least a portion of the repulsive field to between the first and second magnets. The conductor extends between first and second end contacts and is toroidally coiled about the first and second magnets and the shield portion to develop a voltage across the first and second end contacts in response to rotation of the electric machine about the axis of rotation.
FILED	Monday, June 21, 2010
APPL NO	12/819717
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Electrical generator or motor structure 310/178
VIEW PATENT	@ USPTO: Full Text PDF

08248030 — Device for monitoring cell voltage

US 08248030	Doepke et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	Johnson Controls Technology Company (Holland, Michigan)
INVENTOR(S)	Matthias Doepke (Garbsen, Germany); Henning Eisermann (Edermissen, Germany)
ABSTRACT	A device for monitoring a rechargeable battery having a number of electrically connected cells includes at least one current interruption switch for interrupting current flowing through at least one associated cell and a plurality of monitoring units for detecting cell voltage. Each monitoring unit is associated with a single cell and includes a reference voltage unit for producing a defined reference threshold voltage and a voltage comparison unit for comparing the reference threshold voltage with a partial cell voltage of the associated cell. The reference voltage unit is electrically supplied from the cell voltage of the associated cell. The voltage comparison unit is coupled to the at least one current interruption switch for interrupting the current of at least the current flowing through the associated cell, with a defined minimum difference between the reference threshold voltage and the partial cell voltage.
FILED	Monday, July 21, 2008
APPL NO	12/177024
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Battery or capacitor charging or discharging 320/116
VIEW PATENT	@ USPTO: Full Text PDF

08248612 — Oxygen concentration sensors and methods of rapidly measuring the concentration of oxygen in fluids

US 08248612	Parks, II et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S)	UT-Batelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	James E. Parks, II (Knoxville, Tennessee); William P. Partridge, Jr. (Oak Ridge, Tennessee)
ABSTRACT	Provided are sensors and methods of measuring the oxygen concentration of a fluid. An excitation light source is in optical communication with a transducer for transmitting an excitation light that is at least partially absorbed by the transducer. The transducer has a property of photoluminescence, and enters a higher energy state by at least partially absorbing the excitation light and enters a lower energy state through radiation of emitted light, thus producing spectral indicia. A light detection system, which is also in optical communication with the transducer, processes the spectral indicia to determine the concentration of oxygen in the fluid.
FILED	Monday, July 26, 2010
APPL NO	12/843121
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/437
VIEW PATENT	@ USPTO: Full Text PDF

08248809 — Inverter power module with distributed support for direct substrate cooling

US 08248809	Miller et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S)	David Harold Miller (San Pedro, California); Mark D. Korich (Chino Hills, California); Terence G. Ward (Redondo Beach, California); Brooks S. Mann (Redondo Beach, California)
ABSTRACT	Systems and/or methods are provided for an inverter power module with distributed support for direct substrate cooling. An inverter module comprises a power electronic substrate. A first support frame is adapted to house the power electronic substrate and has a first region adapted to allow direct cooling of the power electronic substrate. A gasket is interposed between the power electronic substrate and the first support frame. The gasket is configured to provide a seal between the first region and the power electronic substrate. A second support frame is adapted to house the power electronic substrate and joined to the first support frame to form the seal.
FILED	Tuesday, August 26, 2008
APPL NO	12/198723
ART UNIT	2835 — Electrical Circuits and Systems
CURRENT CPC	Electricity: Electrical systems and devices 361/752
VIEW PATENT	@ USPTO: Full Text PDF

08250389 — Profiling an application for power consumption during execution on a plurality of compute nodes

US 08250389	Archer et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Amanda E. Peters (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota)
ABSTRACT	Methods, apparatus, and products are disclosed for profiling an application for power consumption during execution on a compute node that include: receiving an application for execution on a compute node; identifying a hardware power consumption profile for the compute node, the hardware power consumption profile specifying power consumption for compute node hardware during performance of various processing operations; determining a power consumption profile for the application in dependence upon the application and the hardware power consumption profile for the compute node; and reporting the power consumption profile for the application.
FILED	Thursday, July 03, 2008
APPL NO	12/167302
ART UNIT	2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electrical computers and digital processing systems: Support 713/320
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

08245617 — Non-lethal restraint device with diverse deployability applications

US 08245617	Martinez et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)	Engineering Science Analysis Corporation (Tempe, Arizona)
INVENTOR(S)	Martin A. Martinez (Phoenix, Arizona); Patrick J. Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California)
ABSTRACT	An immobilization device and method of restraining vehicles, persons and animals uses tendrils attached to various devices to engage the target. The immobilization device, system and method includes a housing containing launchable tendrils that are launched from the housing by a propellant. The tendrils may be attached to straps or other elements carried by the immobilization device. The tendrils will engage the target and restrain it if it is a vehicle such as a car, truck, boat, submarine, or like vehicle. In stopping a person or animal the tendrils will deliver a marking package, a shocking package or a snare package to mark, shock or snare the target. Straps may be pulled off the housing leaving the housing near the point of deployment.
FILED	Tuesday, July 20, 2010
APPL NO	12/839911
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ordnance 089/1.340
VIEW PATENT	@ USPTO: Full Text PDF

08246718 — Process for separating carbon dioxide from flue gas using sweep-based membrane separation and absorption steps

US 08246718	Wijmans et al.
FUNDED BY	Department of Energy (DOE) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)	Membrane Technology and Research, Inc (Newark, California)
INVENTOR(S)	Johannes G. Wijmans (Menlo Park, California); Richard W. Baker (Palo Alto, California); Timothy C. Merkel (Menlo Park, California)
ABSTRACT	A gas separation process for treating flue gases from combustion processes, and combustion processes including such gas separation. The invention involves routing a first portion of the flue gas stream to be treated to an absorption-based carbon dioxide capture step, while simultaneously flowing a second portion of the flue gas across the feed side of a membrane, flowing a sweep gas stream, usually air, across the permeate side, then passing the permeate/sweep gas to the combustor.
FILED	Monday, September 13, 2010
APPL NO	13/123342
ART UNIT	1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Gas separation: Processes 095/51
VIEW PATENT	@ USPTO: Full Text PDF

08249682 — Device for measuring concentrations of constituents of tear sample

US 08249682	Cappo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)
ASSIGNEE(S)	Lacrisciences, LLC (Washington, District of Columbia)
INVENTOR(S)	Anthony P. Cappo (New York, New York); Gregory Bennett (New York, New York); Jeffrey P Gilbard (Weston, Massachusetts); Paul T Gavaris (Bethesda, Maryland); Diptabhas Sarkar (Houston, Texas)
ABSTRACT	A medical diagnostic method utilizes a surface plasmon resonance apparatus provided with a sensing surface. A tear sample from an eye of a patient is placed into contact with the sensing surface. The surface plasmon resonance apparatus is then operated to determine concentrations of solutes such as salt and antigenic analytes in the tear sample.
FILED	Thursday, September 06, 2007
APPL NO	11/899596
ART UNIT	3777 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC	Surgery 6/310
VIEW PATENT	@ USPTO: Full Text PDF

Department of Agriculture (USDA)

08246931 — Development of a quail embryo model for the detection of botulinum toxin

US 08246931	Buhr et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Richard J. Buhr (Athens, Georgia); Dianna V. Bourassa (Monroe, Georgia); Larry J. Richardson (Hull, Georgia); Lynda C. Kelley (Watkinsville, Georgia); Nelson A. Cox, Jr. (Athens, Georgia); Robert W. Phillips (Watkinsville, Georgia)
ABSTRACT	A method for using bird eggs to detect the presence of at least one botulinum toxin.
FILED	Thursday, July 23, 2009
APPL NO	12/508380
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/9.100
VIEW PATENT	@ USPTO: Full Text PDF

08246965 — Bacillus isolates and methods of their use to protect against plant pathogens

US 08246965	Jacobsen et al.
FUNDED BY	Department of Agriculture (USDA) Agricultural Research Service (ARS) Cooperative State Research, Education, and Extension Service (CSREES) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S)	Montana State University (Bozeman, Montana)
INVENTOR(S)	Barry Jacobsen (Bozeman, Montana); Nina K. Zidack (Bozeman, Montana); Rebecca Larson (Longmont, Colorado)
ABSTRACT	Bacillus isolates and compositions comprising the same are provided. Also provided are methods of inducing systemic acquired resistance to infection in a plant by applying a composition comprising a Bacillus control agent to said plant wherein said plant is capable of producing defense proteins.
FILED	Friday, August 05, 2011
APPL NO	13/204315
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/246.100
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

08245617 — Non-lethal restraint device with diverse deployability applications

US 08245617	Martinez et al.
FUNDED BY	Department of Homeland Security (DHS) Department of Defense (DOD) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)	Engineering Science Analysis Corporation (Tempe, Arizona)
INVENTOR(S)	Martin A. Martinez (Phoenix, Arizona); Patrick J. Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California)
ABSTRACT	An immobilization device and method of restraining vehicles, persons and animals uses tendrils attached to various devices to engage the target. The immobilization device, system and method includes a housing containing launchable tendrils that are launched from the housing by a propellant. The tendrils may be attached to straps or other elements carried by the immobilization device. The tendrils will engage the target and restrain it if it is a vehicle such as a car, truck, boat, submarine, or like vehicle. In stopping a person or animal the tendrils will deliver a marking package, a shocking package or a snare package to mark, shock or snare the target. Straps may be pulled off the housing leaving the housing near the point of deployment.
FILED	Tuesday, July 20, 2010
APPL NO	12/839911
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ordnance 089/1.340
VIEW PATENT	@ USPTO: Full Text PDF

08249843 — Predicting aerodynamic impacts for small appendages (IRCM installation) on large fixed wing aircraft using computational fluid dynamics

US 08249843	Gendron et al.
FUNDED BY	Department of Homeland Security (DHS)
APPLICANT(S)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Peter Q. Gendron (Merrimack, New Hampshire); Michael R. Mendenhall (Los Gatos, California)
ABSTRACT	A method for predicting aerodynamic impact for small appendages on aircraft, wherein the improvement comprises using an adaptable computational fluid dynamic model of airflow adjacent the appendage by isolating a patch surrounding the small appendage, measuring the load on the patch without the appendage in place and with the appendage in a place and subtracting the two for increasing computational accuracy of the load predictions for the small appendage to be able to measure the effect of the small appendage.
FILED	Thursday, January 08, 2009
APPL NO	12/350601
ART UNIT	2123 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Structural design, modeling, simulation, and emulation 73/9
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

08247419 — Methods of identifying and treating individuals exhibiting mutant kit protein

US 08247419	Lee et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)
ASSIGNEE(S)	Bristol-Myers Squibb Company (Princeton, New Jersey); Oregon Health and Science University (Portland, Oregon); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Francis Y. Lee (Yardley, Pennsylvania); Michael C. Heinrich (Lake Oswego, Oregon)
ABSTRACT	The invention described herein relates to methods of identifying and treating individuals with protein tyrosine kinase associated disorders that have, or may, become resistant to treatment with a kinase inhibitor such as imatinib due to a gain-of-function mutation in KIT tyrosine kinase.
FILED	Friday, June 09, 2006
APPL NO	11/921781
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/252.140
VIEW PATENT	@ USPTO: Full Text PDF

08247451 — ADAM10 and its uses related to infection

US 08247451	Rubin et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee); University of Georgia Research Foundation (Athens, Georgia); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Donald H. Rubin (Nashville, Tennessee); Thomas Hodge (Athens, Georgia); James Murray (Bogart, Georgia)
ABSTRACT	The present invention relates to a protein, ADAM10, ADAM10 nucleic acid sequences and ADAM10 proteins encoded by these sequences that are involved in infection by one or more pathogen such as a virus, a parasite, a bacteria or a fungus or are otherwise associated with the life cycle of a pathogen.
FILED	Tuesday, January 16, 2007
APPL NO	12/160862
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/575
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

08245516 — Shape memory alloy actuated adaptive exhaust nozzle for jet engine

US 08245516	Song et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	University of Houston (Houston, Texas)
INVENTOR(S)	Gangbing Song (Pearland, Texas); Ning Ma (Nanjing, China PRC)
ABSTRACT	The proposed adaptive exhaust nozzle features an innovative use of the shape memory alloy (SMA) actuators for actively control of the opening area of the exhaust nozzle for jet engines. The SMA actuators remotely control the opening area of the exhaust nozzle through a set of mechanism. An important advantage of using SMA actuators is the reduction of weight of the actuator system for variable area exhaust nozzle. Another advantage is that the SMA actuator can be activated using the heat from the exhaust and eliminate the need of other energy source. A prototype has been designed and fabricated. The functionality of the proposed SMA actuated adaptive exhaust nozzle is verified in the open-loop tests.
FILED	Tuesday, August 11, 2009
APPL NO	12/539242
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/771
VIEW PATENT	@ USPTO: Full Text PDF

08250541 — Reversible object code compiler for mathematical models

US 08250541	Santhanam
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Viswanathan Santhanam (Bothell, Washington)
ABSTRACT	A method for verifying a software implementation generated from a model that includes a plurality of model elements is described. The method includes converting a model description into a textual representation of model elements and interconnections between the model elements, defining a series of assembler macros that implement the functionality of the model elements as sequences of assembly instructions for a target processor, compiling the textual representation into an object code image associated with a target processor using the macros, describing the object code image in a context-free grammar, and reproducing the model description from the object code image and the context-free grammar.
FILED	Thursday, September 20, 2007
APPL NO	11/858719
ART UNIT	2193 — Interprocess Communication and Software Development
CURRENT CPC	Data processing: Software development, installation, and management 717/126
VIEW PATENT	@ USPTO: Full Text PDF

Department of Education (ED)

08246180 — Content reflection display systems

US 08246180	West
FUNDED BY	Department of Education (ED)
APPLICANT(S)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Leanne Little West (Atlanta, Georgia)
ABSTRACT	The present invention describes content reflection systems for displaying a select portion of content to a viewer. An exemplary embodiment of the present invention provides a reflecting apparatus comprising a base and a reflective member in communication with the base. The reflective member includes a reflective layer enabled to receive at least a first frequency band of light and a second frequency band of light. Additionally, the reflective layer is enabled to reflect the first frequency band of light and transmit the second frequency band of light. Furthermore, the first frequency band of light includes a first content regarding an audiovisual presentation.
FILED	Tuesday, February 10, 2009
APPL NO	12/368440
ART UNIT	2878 — Optics
CURRENT CPC	Optics: Image projectors 353/121
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

08249807 — Method for determining critical points in location data generated by location-based applications

US 08249807	Barbeau et al.
FUNDED BY	Department of Transportation (USDOT) U.S. State Government State of Florida Florida Department of Transportation (FDOT)
APPLICANT(S)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Sean Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida)
ABSTRACT	Provided is a critical point method used to determine the points of a real-time stream of location data, such as Global Positioning System (GPS) data, that should be retained based on their importance in reconstructing the travel path of a mobile device. The method may run on a mobile device or on a server. When run on a mobile device, the method reduces the amount of data transferred between mediums by only transferring points that are critical to reconstructing the path of travel of the mobile device. This reduction saves power used in the wireless transmission and reception of the non-critical data and the bandwidth used while transmitting non-critical data. The method may be run every time a new position is calculated. When a new position is determined to be a critical point, the point is transmitted. If the new position is not a critical point, then the point is discarded.
FILED	Friday, August 22, 2008
APPL NO	12/196673
ART UNIT	3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/490
VIEW PATENT	@ USPTO: Full Text PDF

Department of the Interior (DOI)

08247226 — Methods of evaluating an immune response to an antigen

US 08247226	Sukumar et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA) Department of the Interior (DOI)
APPLICANT(S)
ASSIGNEE(S)	Sanofi Pasteur Vaxdesign Corp. (Orlando, Florida)
INVENTOR(S)	Selva Sukumar (Berkeley, California); Mohey Eldin M. El Shikh (Richmond, Virginia); John G. Tew (Mechanicsville, Virginia); Guzman Sanchez-Schmitz (Orlando, Florida); Donald Drake, III (Orlando, Florida); Luis Mosquera (Oviedo, Florida); Conan Li (Los Altos, California); Anatoly M. Kachurin (Orlando, Florida); Russell Higbee (Orlando, Florida); Heather Fahlenkamp (Cleveland, Oklahoma); Eric Mishkin (Winter Springs, Florida); William L. Warren (Orlando, Florida)
ABSTRACT	The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
FILED	Thursday, June 23, 2011
APPL NO	13/167115
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/375
VIEW PATENT	@ USPTO: Full Text PDF

National Geospatial Intelligence Agency (NGA)

08250481 — Visualizing geographic-area change detected from high-resolution, remotely sensed imagery

US 08250481	Klaric et al.
FUNDED BY	National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S)	The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Matthew Nicholas Klaric (Columbia, Missouri); Curtis Herbert Davis (Columbia, Missouri); Grant Jason Scott (Columbia, Missouri); Chi-Ren Shyu (Columbia, Missouri); Brian Christopher Claywell (Columbia, Missouri)
ABSTRACT	A method, system, and medium are provided for presenting aspects of change associated with a geographic area that has been captured by high-resolution, remotely sensed imagery. One embodiment of the method includes receiving a query directed at the geographic area that includes one or more inputs, the query seeking an identification of regions associated with the geographic area that are characterized by aspects of change based on the one or more inputs; applying the query to a dataset of geospatial information that stores imagery associated with the geographic area, wherein the dataset includes information that is sufficient to identify the regions, and wherein the imagery is derived from the high-resolution, remotely sensed imagery, which is characterized by having a resolution of three meters or less per pixel; receiving a first results set that includes a first plurality of keys and corresponding change scores, wherein, (1) each key is useable to identify a certain region, and (2) each change score indicates an amount of change in the certain region from a first state to a second state; and presenting at least a portion of the results set in a viewing application.
FILED	Monday, October 20, 2008
APPL NO	12/254654
ART UNIT	2179 — Graphical User Interface and Document Processing
CURRENT CPC	Data processing: Presentation processing of document, operator interface processing, and screen saver display processing 715/765
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

08249807 — Method for determining critical points in location data generated by location-based applications

US 08249807	Barbeau et al.
FUNDED BY	Department of Transportation (USDOT) U.S. State Government State of Florida Florida Department of Transportation (FDOT)
APPLICANT(S)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Sean Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida)
ABSTRACT	Provided is a critical point method used to determine the points of a real-time stream of location data, such as Global Positioning System (GPS) data, that should be retained based on their importance in reconstructing the travel path of a mobile device. The method may run on a mobile device or on a server. When run on a mobile device, the method reduces the amount of data transferred between mediums by only transferring points that are critical to reconstructing the path of travel of the mobile device. This reduction saves power used in the wireless transmission and reception of the non-critical data and the bandwidth used while transmitting non-critical data. The method may be run every time a new position is calculated. When a new position is determined to be a critical point, the point is transmitted. If the new position is not a critical point, then the point is discarded.
FILED	Friday, August 22, 2008
APPL NO	12/196673
ART UNIT	3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/490
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

08247183 — Compositions and methods for diagnosis and treatment of tumors

US 08247183	Takafuji et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Departmant of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Vivian Takafuji (Alexandria, Virginia); Xin Wei Wang (Rockville, Maryland); Paul K. Goldsmith (Rockville, Maryland)
ABSTRACT	Based on the observation of the cooperation of osteopontin (OPN) and matrixmetalloproteinase-9 (MMP-9) in the promotion of the metastatic phenotype, therapies and diagnostic assays are disclosed for the treatment of a tumor that overexpresses OPN, such as hepatocellular carcinoma (HCC), for example metastatic HCC. In one example, methods of treating a tumor include administration of an agent that reduces cellular invasion resulting from the interaction between a fragment of OPN (OPN-5kD) generated by MMP-9 cleavage and CD44 receptor. Examples of such agents include fragments of OPN-5kD and antibodies specific for OPN-5kD. Therapeutic compositions are also provided that include such agents. Also provided are methods of diagnosing or prognosing a tumor, for example by detecting expression of OPN-5kD peptide or OPN-c mRNA in a biological sample obtained from the subject. Also provided are antibodies that specifically bind OPN-5kD.
FILED	Monday, August 30, 2010
APPL NO	12/871669
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.100
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, August 21, 2012.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

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