FedInvent™ Patents

Patent Details for Tuesday, August 28, 2012 

This page was updated on Monday, March 27, 2023 at 03:24 AM GMT

Department of Defense (DOD) 

US 08250850 Adams et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Richard Adams (Chula Vista, California);  Carol A. Becker (Del Mar, California)
ABSTRACT A pollution-free propulsion engine includes a rotating arm, a hollow axle defining a fuel delivery chamber, and hydrogen and oxygen sources. The rotating arm is formed with a detonation chamber, an opening and two tubular ducts therebetween. The axle is inserted into the opening. A pair of holes is formed in the axle to establish paths of fluid communication from the fuel delivery chamber through the ducts and into the detonation chamber as the rotating arm turns. The hydrogen source comprises a thin palladium binding layer deposited onto an aluminum sheet. Hydrogen molecules that are trapped in the binding layer are released, and the hydrogen is fed into the delivery chamber, through one duct and into the detonation chamber. At the same time, oxygen is delivered into the detonation chamber through the other duct, and the oxygen-hydrogen combination is detonated to release energy, which is converted into mechanical energy.
FILED Wednesday, January 18, 2012
APPL NO 13/352799
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/39.340
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08250979 Neff
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Daniel R. Neff (Jasper, Indiana)
ABSTRACT An ejectable device is provided having multiple ejection bays. The ejectable device includes an impulse cartridge having multiple charges that are independently activatable. The ejectable device further includes an orientation adapter that allows reliable connectivity between the impulse cartridge and a signal source.
FILED Tuesday, September 28, 2010
APPL NO 12/892521
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/202.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08250980 Mackie-Smith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James Mackie-Smith (Hughesville, Maryland);  Edward Tersine (Indian Head, Maryland);  Ryan Barrow (Issue, Maryland)
ABSTRACT An exemplary firing pin with a release mechanism apparatus at least partially composed of an elastic thermoplastic material. The apparatus includes a rod with a first end portion, a middle portion, and a second end portion. The first end portion includes an integral cage-like element with a plurality of restraining wall elements, which, interiorly, are undercut defining an interior chamber with a volume sufficient to accommodate a cable stop element and define an aperture in communication with the chamber. The aperture is sized to accommodate a cable or the like, but small enough to prevent the stop element seated in the chamber from moving, so long as the restraining wall elements are constrained. The restraining wall elements are generally constrained by a substantially rigid element, such that they cannot deform, flaring open, even if the cable is under tension.
FILED Thursday, May 20, 2010
APPL NO 12/802451
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/204
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08250981 Gotzmer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Carl Gotzmer (Accokeek, Maryland);  Steven Kim (Crofton, Maryland)
ABSTRACT An underwater hydro-reactive explosive system includes a pressure vessel with a central section of water disposed between identical sections of a material selected from the group consisting of thermites, intermetallics, nano-sized metallic particles, and micro-sized metallic particles. The water is provided in a stoichiometric quantity that provides a complete reaction with the material following simultaneous detonation of the sections thereof.
FILED Thursday, January 21, 2010
APPL NO 12/657878
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/314
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08250987 Morley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Andrew Morley (New York, New York);  Mohan J. Palathingal (Oradell, New Jersey);  Leon Manole (Great Meadows, New Jersey);  Ernest L. Logsdon, Jr. (Newton, New Jersey)
ABSTRACT A Kinetic Energy penetrator round is shown effective in neutralizing incoming air borne threat munitions such as rockets, artillery, or mortars for instance, without posing a threat in urban environments to harm bystanders on the ground. There are also no hazards or expense with this round of cleaning up unexploded ordnance, which might have occurred with other types of rounds due to unreliability of self destruct mechanisms. Shown herein is a kinetic energy penetrator for air defense that merely self destructs beyond its operational range into fragments that are not lethal to personnel on ground; no pyrotechnic or energetic materials means are used to activate this self destruct process. A full bore projectile structure is shown that is composed of plural axi-symmetric circular disks stacked on each other and tied by a shape memory metal wire of Nitinol. While operational as a joined group, the disks are a formidable round to kill an incoming air target. After the self destruct phase however, each disk is separated from adjacent disks on either side by a spring mechanism that enables separation after the process is initiated in flight when the Nitinol wire deforms due to heating from air drag. Each disk then proceeds alone with low enough terminal kinetic energy on the ground to be less than lethal.
FILED Tuesday, July 14, 2009
APPL NO 12/502307
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/506
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251123 Farris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) John R. Farris (Bolton, Connecticut);  Tracy A. Propheter-Hinckley (Manchester, Connecticut);  Douglas C. Jenne (West Hartford, Connecticut);  Matthew S. Gleiner (Vernon, Connecticut);  Peter H. Thomas (West Hartford, Connecticut)
ABSTRACT A casting core assembly includes a metallic core and a ceramic core. The process for forming the casting core assembly includes inserting a ceramic plug of a metallic core and ceramic plug core subassembly into a compartment of the ceramic core. The ceramic plug is secured to the ceramic core.
FILED Thursday, December 30, 2010
APPL NO 12/981650
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal founding
164/28
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251863 Faulring et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) HDT Robotics, Inc. (Fredericksburg, Virginia)
INVENTOR(S) Eric L. Faulring (Alexandria, Virginia);  Thomas Moyer (Salt Lake City, Utah);  Julio Santos-Munne (Glenview, Illinois);  Alexander Makhlin (Chicago, Illinois);  J. Edward Colgate (Evanston, Illinois);  Michael Peshkin (Evanston, Illinois)
ABSTRACT A transmission or actuator offering multiple rotational outputs proportionate in speed to that of a common rotational input, each output according to its own ratio. The ratios are continuously variable between positive and negative values, including zero, and may be varied by electromechanical actuators under computer control. The transmission relates the output speeds one to another under computer control, and thus makes possible the establishment of virtual surfaces and other haptic effects in a multidimensional workspace to which the transmission outputs are kinematically linked. An example of such a workspace is that of a robotic or prosthetic hand.
FILED Tuesday, September 04, 2007
APPL NO 11/849953
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Friction gear transmission systems or components
476/38
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251943 Spencer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Jerry R. Spencer (Rio Medina, Texas);  Todd E. Rasmussen (Fair Oaks Ranch, Texas);  Shaun M. Gifford (San Antonio, Texas)
ABSTRACT A novel shunt comprises: a first lumen having a first end and a second end, wherein the first lumen is composed of a polydimethylsiloxane material; a bulb-shaped portion positioned on each of the first end and the second end; a reinforcing spring extending along the first lumen from the first end and the second end; and a second lumen having a first end and a second end, wherein the first end is connected to a center portion of the first lumen and the second end is connected to a valve.
FILED Wednesday, January 06, 2010
APPL NO 12/652981
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
64/8
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252370 Young et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Ming-Wan Young (Basking Ridge, New Jersey);  Costas George Gogos (Wyckoff, New Jersey);  Jun Yang (Kearny, New Jersey);  Rajesh Dave (Short Hills, New Jersey);  Linje Zhu (Newark, New Jersey);  Peter Bonnett (Succasunna, New Jersey);  William Schepige (West Orange, New Jersey)
ABSTRACT A method for the continuous production of finely ground particulates coated with a barrier, or other desirable film wherein the coated particulates exhibit a diameter of less than 10 microns. In an exemplary embodiment, large coated particulates are introduced into a fluid energy, or jet mill, along with smaller, uncoated particulates. As the particulates collide within the mill they are comminuted, and an amount of coating is transferred from the coated particulates to the uncoated ones such that they become sufficiently coated and size-reduced to a desired size. Alternatively, uncoated particulates are milled and coated during their milling. Still alternatively, uncoated particulates are milled and subsequently directed through an atomized mist of coating material wherein the size of the mist droplets are as large, or larger than the directed particulates.
FILED Friday, July 14, 2006
APPL NO 11/457501
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Coating processes
427/212
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252517 Thomas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Edwin L. Thomas (Natick, Massachusetts);  Patrick Seamus Doyle (Boston, Massachusetts);  Dhananjay Dendukuri (Begumpet, India);  Ji-Hyun Jang (Cambridge, Massachusetts);  Chaitanya K. Ullal (Goettingen, Germany)
ABSTRACT Stop flow interference lithography system for high throughput synthesis of 3-dimensionally patterned polymer particles. The system includes a microfluidic channel containing a stationary oligomer film and a phase mask located adjacent to the microfluidic channel. A source of collimated light is provided for passing the collimated light through the phase mask and into the microfluidic channel for interaction with the oligomer. The passage of the collimated light through the phase mask generates a 3-dimensional distribution of light intensity to induce crosslinking of the oligomer in high intensity regions thereby forming 3-dimensional structures.
FILED Thursday, July 16, 2009
APPL NO 12/503935
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252607 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Gautam Gupta (Albuquerque, New Mexico);  Gabriel Lopez (Albuquerque, New Mexico);  Plamen Atanassov (Albuquerque, New Mexico)
ABSTRACT The disclosure provides a simple and effective way of synthesizing robust organic-inorganic hybrid gels and ultra-thin films using vaporization of a gel precursor. The gels are synthesized at relatively low temperature allowing the activity of the immobilized species to be maintained. The disclosure provides robust, synthetic, selective, active and/or passive transport systems in the form of functional biologically active species and mechanisms for forming them. These systems allow selective and passive or active transport of ionic, molecular and biological species through the incorporation of functional biological molecules and biomolecular assemblies in a rigid matrix.
FILED Friday, June 06, 2008
APPL NO 12/134874
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/527
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252711 Olson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Tim Olson (Albuquerque, New Mexico);  Plamen Atanassov (Albuquerque, New Mexico)
ABSTRACT A highly dispersed, unsupported, electrocatalyst made of pyrolyzed porphyries and a method for synthesizing the same. The disclosed synthesis procedure allows for optimization of pore size and therefore transport properties. Compounds suitable for use include transition metal N4-chelates such as, but not necessarily limited to, N4-chelates containing different metal centers including Co, Fe, Mn, Ni, Ru, Cu, etc., and other N4-chelates such as porphyrin, phthalocyanies, and structures based on their pyro products.
FILED Monday, February 22, 2010
APPL NO 12/709618
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/164
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252756 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
Nanoscale Science and Engineering Centers (NSF-NSEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Nathaniel L. Rosi (Pittsburgh, Pennsylvania);  C. Shad Thaxton (Chicago, Illinois);  David A. Giljohann (Chicago, Illinois)
ABSTRACT Materials and methods for regulating gene expression using nanoparticles functionalized with antisense oligonucleotides are provided.
FILED Thursday, June 08, 2006
APPL NO 11/917680
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252772 Torti et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)
ASSIGNEE(S) Wake Forest University (Winston Salem, North Carolina)
INVENTOR(S) Suzy Torti (Winston-Salem, North Carolina);  Frank Torti (Winston-Salem, North Carolina);  David Loren Carroll (Winston-Salem, North Carolina);  Steven Akman (Greensboro, North Carolina);  Omkaram Nalamasu (San Jose, California);  Pulickel Ajayan (Houston, Texas)
ABSTRACT The present invention provides nanoscale and microscale compositions useful for a variety of purposes, including the diagnosis and treatment of diseases. In one embodiment, the present invention provides a disease treatment system comprising a thermal induction agent and a radiation source, wherein the thermal induction agent comprises at least one carbon nanotube, at least one carbon microtube, or a mixture thereof.
FILED Friday, May 25, 2007
APPL NO 12/302382
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/64
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252823 Dasgupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Ramanuj Dasgupta (New York, New York);  Foster Gonsalves (Long Island City, New York)
ABSTRACT A series of oxazole and thiazole compounds are shown herein to be small molecule inhibitors of the Wnt pathway that specifically target the activity of the stabilized pool of β-cat oxazole and thiazole compounds are disclosed that have a formula represented by the following:
The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, cancer, and others.
FILED Wednesday, January 28, 2009
APPL NO 12/322070
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/374
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253085 Lichtenberg-Scanlan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Adam Lichtenberg-Scanlan (Jersey City, New Jersey);  Christopher Stout (Hoboken, New Jersey)
ABSTRACT A projectile may include a body and a base fixed to a rear end of the body. The base may include a gas cavity and an opening extending from a rear end of the base to the gas cavity. A retention plug may be disposed in the opening wherein a fit between the retention plug and the opening is such that propellant gas pressure in the gas cavity forces the retention plug out of the opening. The retention plug may include at least one gas conduit between an outer surface of the retention plug and the gas cavity. A plurality of fins may be rotatably fixed to the base. The fins may have a folded position and a deployed position.
FILED Wednesday, August 18, 2010
APPL NO 12/858656
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/3.270
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253102 Slagle
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Glenn B. Slagle (McLean, Virginia)
ABSTRACT A thermal imager including a cell containing a fluid whose refractive index varies with temperature and, optical components for focusing the infrared image of a scene to be viewed onto the cell to produce local temperature differences across the fluid. The local temperature differences give rise to local refractive index differences. The thermal imager also includes a Schlieren optical system for reading out the local refractive index differences to reproduce the scene.
FILED Wednesday, September 30, 2009
APPL NO 12/570168
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/332
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253119 Brodie et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) KLA-Tencor Corporation (Milpitas, California)
INVENTOR(S) Alan D. Brodie (Palo Alto, California);  Paul Petric (Pleasanton, California);  Mark A. McCord (Los Gatos, California)
ABSTRACT One embodiment relates to an apparatus of a dynamic pattern generator for reflection electron beam lithography. The apparatus includes a plurality of base electrodes in a two-dimensional array, an insulating border surrounding each base electrode so as to electrically isolate the base electrodes from each other; and a sidewall surrounding each base electrode. The sidewall comprises a plurality of stacked electrodes which are separated by insulating layers. In addition, the base electrodes are advantageously shaped so as to be concave. Furthermore, a conformal coating may be advantageously applied over the base electrodes and sidewalls. Another embodiment relates to an apparatus for reflection electron beam lithography. The apparatus includes a shadow mask configured to form an array of incident electron beamlets. The shadow mask comprises an array of holes which correspond one-to-one with an array of pixel pads of an electron reflective patterned structure. Other embodiments, aspects and features are disclosed.
FILED Monday, July 27, 2009
APPL NO 12/510049
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/492.220
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253215 Yao
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Wavefront Holdings, LLC (Basking Ridge, New Jersey)
INVENTOR(S) Jie Yao (Princeton, New Jersey)
ABSTRACT A two-terminal mesa phototransistor and a method for making it are disclosed. The photo transistor has a mesa structure having a substantially planar semiconductor surface. In the mesa structure is a first semiconductor region of a first doping type, and a second semiconductor region of a second doping type opposite to that of the first semiconductor region, forming a first semiconductor junction with the first region. In addition, a third semiconductor region of the first doping type forms a second semiconductor junction with the second region. The structure also includes a dielectric layer. The second semiconductor region, first semiconductor junction, and second semiconductor junction each has an intersection with the substantially planar semiconductor surface. The dielectric covers, and is in physical contact with, all of the intersections.
FILED Thursday, January 14, 2010
APPL NO 12/687257
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/461
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253626 Schantz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institute for Occupational Safety and Health (NIOSH)
APPLICANT(S)
ASSIGNEE(S) Q-Track Corporation (Huntsville, Alabama)
INVENTOR(S) Hans Gregory Schantz (Huntsville, Alabama);  Andrew Compston (Stanford, California);  Robert DePierre (Huntsville, Alabama);  James Matthew Barron (Huntsville, Alabama)
ABSTRACT A multiple phase state near-field electromagnetic location and communication system includes a multiple phase state near-field transmitter, and a near-field locator receiver. The near-field transmitter is capable of operation in at least two states and each of these at least two states generates a state characteristic difference detected at the near-field locator receiver. The state characteristic difference may be employed for location determination, communication or both. The present invention is particularly well-suited for use in conjunction with a near-field electromagnetic ranging system. In further embodiments, a multiple phase state near-field electromagnetic location and communication process includes the steps of determining a transmission state for a near-field quadrature transmitter, transmitting a near-field transmission corresponding to said transmission state, receiving a near-field transmission corresponding to said transmission state, and determining a difference between at least two properties of said near-field transmission where the difference is characteristic of and corresponding to the transmission state.
FILED Monday, February 23, 2009
APPL NO 12/391209
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications: Directive radio wave systems and devices
342/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253932 Cole
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Walter P. Cole (Springfield, Virginia)
ABSTRACT A near-IR laser laser-and-corner cube system for determining the refractive-index structure parameter by providing the return power of the retroreflected laser beam from the corner cube, which return power correlates to the refractive-index structure parameter. The system is economical, physically containing only (1) the laser which emits a near-IR wavelength output beam, (2) a 50/50 splitter, to receive back the retroreflected return beam from the corner cube along the same optical axis as the output beam, in a monostatic configuration; (3) the target corner cube; (4) a receiving focus lens; (5) a spectral filter and (6) a power meter to provide the monostatic measurement of the return power. Critically the ratio of the area of the corner cube to that of the receiving focus lens is at least 1:2, to obtain meaningful power measurements—to correlate to pre-calculated refractive-index structure parameters.
FILED Monday, June 21, 2010
APPL NO 12/819410
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/128
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US 08254086 Mastro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael A Mastro (Fairfax, Virginia);  Francis J. Kub (Arnold, Maryland)
ABSTRACT A process to deposit a conformal coating of manganese oxide nanocrystals within a high surface area connected pore structure of a carbon paper electrode. A two-step process is utilized. In the first step the carbon paper electrode is immersed in an alkaline manganese oxide solution to form a nanocrystal seed layer on the surface and within the pores of the carbon paper. In the second step the seeded carbon paper is immersed in an acidic manganese oxide solution. The result is a densely packed continuous conformal nanocrystal coating both on the surface of the carbon and deep within its pores. The carbon paper is highly suitable for use as an electrode in a supercapacitor.
FILED Tuesday, July 13, 2010
APPL NO 12/835127
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/502
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254162 Butler
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Grandis, Inc. (San Jose, California)
INVENTOR(S) Willam H. Butler (Tuscaloosa, Alabama)
ABSTRACT A method and system for providing a magnetic junction are described. The method and system include providing a free layer, a symmetry filter, and a pinned layer. The free layer has a first magnetic moment switchable between stable states when a write current is passed through the magnetic junction. The symmetry filter transmits charge carriers having a first symmetry with higher probability than charge carriers having another symmetry. The pinned layer has a second magnetic moment pinned in a direction. The symmetry filter resides between the free layer and the pinned layer. At least one of the free layer and the pinned layer lies in a plane, has the charge carriers of the first symmetry in a spin channel at a Fermi level, lacks the charge carriers of the first symmetry at the Fermi level in another spin channel, and has a nonzero magnetic moment component perpendicular to the plane.
FILED Monday, January 11, 2010
APPL NO 12/685418
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/158
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254210 Peacock et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) G. Scott Peacock (Columbia, Maryland);  Robert M. Patterson (Sykesville, Maryland)
ABSTRACT Techniques include determining coefficients of a complex auto regression (AR) model to fit a complex average spectrum at a base frequency resolution of a set of one or more measured acoustic beams during a time block. Residuals derived by filtering actual data through an inverse of the AR model are determined at frequencies below a first threshold frequency. A quantized spectrum of the residuals is determined at the base frequency resolution. Magnitude, phase, and frequency bin at the base frequency resolution are determined for each peak of a set of one or more narrowband peaks above a second threshold frequency for the set of one or more measured acoustic beams. A message is sent, which indicates without loss the coefficients of the AR model, the quantized spectrum of the residuals, and the frequency bin, magnitude and phase for each peak of the set of one or more narrowband peaks.
FILED Friday, December 11, 2009
APPL NO 12/636186
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/131
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254419 Savage-Leuchs et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Matthias P. Savage-Leuchs (Woodinville, Washington);  Lawrence A. Borschowa (Woodinville, Washington);  Eric C. Honea (Seattle, Washington);  Jason D. Henrie (Snohomish, Washington)
ABSTRACT Apparatus and method for generating controlled-linewidth laser-seed-signals for high-powered fiber-laser amplifier systems. In some embodiments, the natural chirp (frequency change of laser light over a short start-up time) of a DBR laser diode when driven by pulsed current is used to broaden the linewidth of the laser output, while adjusting the peak current and/or the pulse duration to obtain the desired linewidth.
FILED Tuesday, August 02, 2011
APPL NO 13/196767
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/25
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254433 Baker et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) David W. Baker (Tucson, Arizona);  Joel C. Blumke (Tucson, Arizona);  Ralston S. Robertson (Northridge, California);  Chester Lo (Los Angeles, California)
ABSTRACT Provided is a non-federated multi-function exciter. The non-federated multi-function exciter includes a waveform generator subsystem operable to provide waveforms programmable in time, duration, slope and frequency. A transmission subsystem is coupled to the waveform generator, the transmission subsystem having a first upconverter and a second upconverter coupled to the first upconverter. A communication modulation subsystem is coupled to the second upconverter of the transmission subsystem. A reference clock subsystem coupled to the waveform generator subsystem, the transmit subsystem and the communication modulation subsystem. The non-federated multi-function exciter is operable to generate interleaved radar and communication signals.
FILED Monday, April 21, 2008
APPL NO 12/106865
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/219
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254491 Dally
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William J. Dally (Stanford, California)
ABSTRACT An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to emphasize transition signal levels relative to repeated signal levels. The preferred equalizer includes an FIR transition filter using a look-up table. Parallel circuits including FIR filters and digital-to-analog converters provide a high speed equalizer with lower speed circuitry. The equalizer is particularly suited to in-cabinet and local area network transmissions where feedback circuitry facilitates adaptive training of the equalizer.
FILED Thursday, August 31, 2006
APPL NO 11/514735
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254634 Mathan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Santosh Mathan (Seattle, Washington);  Misha Pavel (Portland, Oregon);  Deniz Erdogmus (Winchester, Massachusetts);  Kenneth Hild (Portland, Oregon);  Rida Hamza (Maple Grove, Minnesota);  Kwong Wing Au (Bloomington, Minnesota)
ABSTRACT Methods and apparatus are provided for dividing an image into a plurality of image chips for presentation on a display. Potential objects of interest are detected within an image by detecting features therein that correspond to objects of interest. The image is uniformly divided into a plurality of preliminary image chips. Triage image chips are generated by automatically adjusting each preliminary image chip such that the potential objects of interest detected within each preliminary image chip are at least substantially centered in each preliminary image chip.
FILED Friday, February 27, 2009
APPL NO 12/395217
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/103
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US 08254714 Pauca et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S)
ASSIGNEE(S) Wake Forest University (Winston-Salem, North Carolina)
INVENTOR(S) Pau'l Pauca (Winston-Salem, North Carolina);  Sudhakar Prasad (Albuquerque, New Mexico);  Todd Torgersen (Pfafftown, North Carolina);  Robert J. Plemmons (Winston-Salem, North Carolina)
ABSTRACT Methods and systems for designing electromagnetic wave filters and electromagnetic wave filters designed using the methods and systems are disclosed. In one method, functions are selected whose linear combination define the surface of a filter for producing a desired phase-encoded image. Free parameter values are selected for the function and are varied. The values of the free parameters are observed with regard to an optimization function. Final values of the free parameters are selected based on the optimization function having a specific value or range of values.
FILED Thursday, September 16, 2004
APPL NO 10/943092
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/260
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255034 Heller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Abbott Diabetes Care Inc. (Alameda, California)
INVENTOR(S) Adam Heller (Austin, Texas);  Pawel Rowinski (Austin, Texas);  Benjamin J. Feldman (Oakland, California)
ABSTRACT The present invention is directed to membranes composed liquid crystals having continuous aqueous channels, such as a lyotropic liquid crystal, including a cubic phase lyotropic liquid crystal, and to electrochemical sensors equipped with such membranes. The membranes are useful in limiting the diffusion of an analyte to a working electrode in an electrochemical sensor so that the sensor does not saturate and/or remains linearly responsive over a large range of analyte concentrations. Electrochemical sensors equipped with membranes of the present invention demonstrate considerable sensitivity and stability, and a large signal-to-noise ratio, in a variety of conditions.
FILED Friday, November 30, 2007
APPL NO 11/948915
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/347
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255093 Layton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Jacob Kyle Layton (Green Valley, Arizona);  Morgan J. Bakarich (Tucson, Arizona);  Donald J. Lacey (Tucson, Arizona)
ABSTRACT Embodiments of a kit, automotive control pedestal and system to adapt an automotive vehicle for remote operation are disclosed. The pedestal mounts in place of a driver's seat of the vehicle to allow both human and remote operation of the vehicle. The kit includes the pedestal with a steering servo, a hydraulic brake servo, a throttle control servo, and a gear-selection linear actuator mounted thereon. The kit may also include a control system and a video transmission system for remote operation.
FILED Friday, August 29, 2008
APPL NO 12/201472
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255153 Fregene
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Kingsley Fregene (Andover, Minnesota)
ABSTRACT This invention provides a system and method for automatically inferring when a target that is being tracked by an aerial vehicle is doing something significant (e.g. stopping suddenly, changing direction quickly or getting out of track view), and consequently alerting an operator. The alerting system also provides a classification of what the target is doing. It frees the operator from continuously monitoring the imagery stream so the operator can perform other tasks.
FILED Wednesday, January 23, 2008
APPL NO 12/018641
ART UNIT 3627 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/408
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255344 Ferringer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Matthew Phillip Ferringer (Round Hill, Virginia);  Ronald Scott Clifton (Leesburg, Virginia);  Timothy Guy Thompson (Purcellville, Virginia)
ABSTRACT The systems and methods may include receiving an initial population of parent chromosome data structures, where each parent chromosome data structure provides a plurality of genes; selecting pairs of parent chromosome data structures; applying at least one evolutionary operator to the genes of the selected pairs to generate a plurality of child chromosome data structures; allocating, the generated plurality of child chromosome structures to a plurality slave processors, where each slave processor evaluates one or more of the plurality of child chromosome data structures and generates respective objective function values; receiving objective function values for a portion of the plurality of allocated child chromosome data structures; merging the parent chromosome data structures with the received portion of the child chromosome data structures for which objective function values have been received; and identifying a portion of the merged set of chromosome data structures as an elite set of chromosome data structures.
FILED Monday, August 31, 2009
APPL NO 12/550801
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255345 Ferringer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Matthew Phillip Ferringer (Round Hill, Virginia);  Timothy Guy Thompson (Purcellville, Virginia)
ABSTRACT Systems and methods may include obtaining an input population of parent chromosome data structures, where each parent chromosome data structure provides having a plurality of genes representative of variables in which associated values are permitted to evolve; selecting pairs of parent chromosome data structures from the input population; allocating the selected pairs of parent chromosome data structures to respective ones of a plurality of slave processors, where each slave processor applies an evolutionary process to genes of the allocated pair to generate a plurality of child chromosome data structures; receiving a portion of the plurality of child chromosome data structures generated by the plurality of slave processors; merging the parent chromosome data structures with at least the received portion of the child chromosome data structures to generate a merged set of chromosome data structures; and identifying a portion of the merged set of chromosome data structures as an elite set of chromosome data structures.
FILED Monday, August 31, 2009
APPL NO 12/550829
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255427 Huch
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Alan T. Huch (Richardson, Texas)
ABSTRACT According to one embodiment, a computer-readable medium has computer-executable instructions that, when executed by a computer, are configured to receive an input schema. The input schema specifies how to represent one or more elements in a document. One or more rules are received. The input schema is analyzed for conformance to the one or more rules. If the input schema does not conform to the one or more rules, a modified schema is generated based on the input schema. The modified schema specifies how to represent the one or more elements in the documents in conformance with the one or more rules.
FILED Tuesday, August 18, 2009
APPL NO 12/542831
ART UNIT 2161 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/802
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255554 Andrade et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Henrique Andrade (Croton-on-Hudson, New York);  Bugra Gedik (White Plains, New York);  Sujay Sunil Parekh (Dobbs Ferry, New York);  Kun-Lung Wu (Yorktown Heights, New York);  Xiaolan Zhang (Champaign, Illinois)
ABSTRACT Techniques for composing an application resource model in a data stream processing system are disclosed. The application resource model may be used to understand what resources will be consumed by an application when executed by the data stream processing system. For example, a method for composing an application resource model for a data stream processing system comprises the following steps. One or more operator-level metrics are obtained from an execution of a data stream processing application in accordance with a first configuration. The application is executed by one or more nodes of the data stream processing system, and the application is comprised of one or more processing elements that are comprised of one or more operators. One or more operator-level resource functions are generated based on the obtained one or more operator-level metrics. A processing element-level resource function is generated based on the one or more generated operator-level resource functions. The processing element-level resource function represents an application resource model usable for predicting one or more characteristics of the application executed in accordance with a second configuration.
FILED Thursday, May 14, 2009
APPL NO 12/466017
ART UNIT 2456 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/231
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255591 Bohrer et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Patrick Joseph Bohrer (Austin, Texas);  Ahmed Gheith (Round Rock, Texas);  Peter Heiner Hochschild (New York, New York);  Ramakrishnan Rajamony (Austin, Texas);  Hazim Shafi (Austin, Texas);  Balaram Sinharoy (Poughkeepsie, New York)
ABSTRACT A method and apparatus for managing cache injection in a multiprocessor system reduces processing time associated with direct memory access transfers in a symmetrical multiprocessor (SMP) or a non-uniform memory access (NUMA) multiprocessor environment. The method and apparatus either detect the target processor for DMA completion or direct processing of DMA completion to a particular processor, thereby enabling cache injection to a cache that is coupled with processor that executes the DMA completion routine processing the data injected into the cache. The target processor may be identified by determining the processor handling the interrupt that occurs on completion of the DMA transfer. Alternatively or in conjunction with target processor identification, an interrupt handler may queue a deferred procedure call to the target processor to process the transferred data. In NUMA multiprocessor systems, the completing processor/target memory is chosen for accessibility of the target memory to the processor and associated cache.
FILED Thursday, September 23, 2004
APPL NO 10/948407
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital data processing systems: Input/output
710/22
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255631 Chen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lei Chen (Austin, Texas);  Lixin Zhang (Austin, Texas)
ABSTRACT A method, processor, and data processing system for implementing a framework for priority-based scheduling and throttling of prefetching operations. A prefetch engine (PE) assigns a priority to a first prefetch stream, indicating a relative priority for scheduling prefetch operations of the first prefetch stream. The PE monitors activity within the data processing system and dynamically updates the priority of the first prefetch stream based on the activity (or lack thereof). Low priority streams may be discarded. The PE also schedules prefetching in a priority-based scheduling sequence that corresponds to the priority currently assigned to the scheduled active streams. When there are no prefetches within a prefetch queue, the PE triggers the active streams to provide prefetches for issuing. The PE determines when to throttle prefetching, based on the current usage level of resources relevant to completing the prefetch.
FILED Friday, February 01, 2008
APPL NO 12/024389
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/137
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255635 Arimilli et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lakshminarayana B. Arimilli (Austin, Texas);  Ravi K. Arimilli (Austin, Texas);  Jerry D. Lewis (Round Rock, Texas);  Warren E. Maule (Cedar Park, Texas)
ABSTRACT According to method of data processing in a multiprocessor data processing system, in response to a processor request to modify a target granule of a target cache line of data containing multiple granules, a processing unit originates on an interconnect of the multiprocessor data processing system a data-claim-partial request that requests permission to promote only the target granule of the target cache line to a unique copy with an intent to modify the target granule. In response to a combined response to the data-claim-partial request indicating success (the combined response representing a system-wide response to the data-claim-partial-request), the processing unit promotes only the target granule of the target cache line to a unique copy by updating a coherency state of the target granule and retaining a coherency state of at least one other granule of the target cache line.
FILED Friday, February 01, 2008
APPL NO 12/024392
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/141
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255852 Challenger et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) James R. Challenger (Garrison, New York);  Louis R. Degenaro (White Plains, New York);  James R. Giles (Yorktown Heights, New York);  Paul Reed (Brookline, Massachusetts);  Rohit Wagle (Elmsford, New York)
ABSTRACT A distributable and serializable finite state machine and methods for using the distributable and serializable finite state machine are provided wherein finite state machine instance can be location-shifted, time-shifted or location-shift and time-shifted, for example by serializing and deserializing each instance. Each instance can be located-shifted between agents, and a persistent memory storage location is provided to facilitate both location-shifting and time-shifting. Finite state machine instances and the actions that make up each instance can be run in a distributed fashion among a plurality of agents.
FILED Friday, August 14, 2009
APPL NO 12/541830
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/116
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255913 Arimilli et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lakshminarayana B. Arimilli (Austin, Texas);  Robert S. Blackmore (Poughkeepsie, New York);  Gheorghe C. Cascaval (Carmel, New York);  Ramakrishnan Rajamony (Austin, Texas)
ABSTRACT In a global shared memory (GSM) environment, a method provides local notification of completion of a global shared memory (GSM) operation processed by a first task executing at a local node of the distributed system. The system includes multiple nodes on which different tasks of a single job execute and perform GSM operations that are received from a second task via a via host fabric interface (HFI) and associated HFR window assigned to the first tasks. The local task initiates execution of a GSM operation on the local node. The task then monitors for and detects a completion of the execution of the GSM operation on the local node. When the task detects completion of the execution of the GSM operation, the task issues an internal notification to inform the locally-executing tasks of the completion of the GSM operation.
FILED Friday, February 01, 2008
APPL NO 12/024427
ART UNIT 2195 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers and digital processing systems: Virtual machine task or process management or task management/control
718/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE43612 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Research Service Award (NRSA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniel Griffith Anderson (Sudbury, Massachusetts);  David M. Lynn (Middleton, Wisconsin);  Akin Akinc (Needham, Massachusetts);  Robert S. Langer (Newton, Massachusetts)
ABSTRACT Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. A system for preparing and screening polymers in parallel using semi-automated robotic fluid delivery systems is also provided.
FILED Monday, September 28, 2009
APPL NO 12/568481
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/78.370
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 08250903 McDevitt et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  University of Massachusetts (Shrewsbury, Massachusetts)
INVENTOR(S) James McDevitt (Boston, Massachusetts);  Donald Milton (Lexington, Massachusetts);  Petros Koutrakis (Weston, Massachusetts);  Stephen T. Ferguson (North Billerica, Massachusetts);  Jack M. Wolfson (Jamaica Plain, Massachusetts)
ABSTRACT Provided are devices and methods for the collection of bioaerosols (such as viruses, bacteria, and proteins) from the exhaled breath of humans and/or animals, for the purpose of determining, for example, particle size, generation rate, diseases and interventions for particle release.
FILED Tuesday, March 23, 2010
APPL NO 12/729669
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/23.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251926 Barlow et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Steven M. Barlow (Lawrence, Kansas);  Donald S. Finan (Boulder, Colorado)
ABSTRACT The present subject matter is suited for evaluating biomechanics and electrophysiology of an infant's orofacial system during sucking. The present subject matter includes at least one orofacial sensor and a processor. In various examples, the present subject matter additionally includes one or a combination of: a pacifier having a baglet, a receiver assembly, a stimulation device, a memory, a display, and data acquisition and analysis software. Advantageously, the present subject may non-invasively sample and analyze suck and may stimulate nerve endings in the face of an infant.
FILED Monday, August 22, 2005
APPL NO 11/209029
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/590
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251941 Humes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  CytoPherx, Inc. (Ann Arbor, Michigan)
INVENTOR(S) H. David Humes (Ann Arbor, Michigan);  Deborah Buffington (Ann Arbor, Michigan)
ABSTRACT The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action.
FILED Friday, August 29, 2008
APPL NO 12/201576
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
64/6.30
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252277 Mohr et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Ian Mohr (New York, New York);  Matthew Mulvey (New York, New York)
ABSTRACT The present invention relates to an avirulent, oncolytic herpes simplex virus modified from a wild-type herpes simplex virus so that both γ134.5 genes of the virus have been deleted and each replaced with an interferon-resistance gene that is expressed as an immediate-early gene. The present invention also relates to a pharmaceutical composition that includes the modified herpes simplex virus of the present invention and a pharmaceutically acceptable vehicle for in situ administration to tumor cells. Also provided in the present invention are methods for killing tumor cells in a subject and for immunizing a subject against an infectious disease, cancer, or an autoimmune disease that involve administering to a subject the modified avirulent, oncolytic herpes simplex virus of the present invention.
FILED Tuesday, April 27, 2010
APPL NO 12/767973
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
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US 08252280 Verfaillie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Catherine M. Verfaillie (St. Paul, Minnesota);  Robert Gallegos (Apple Valley, Minnesota);  Michael Jerosch-Herold (Portland, Oregon)
ABSTRACT The present invention relates to methods of increasing function and/or mass in damaged striated muscle tissue of interest (e.g., cardiac or muscle tissue) by providing of a population of multipotent adult progenitor cells (“MAPCs”), which effectively generate new striated muscle over time.
FILED Wednesday, May 11, 2011
APPL NO 13/105372
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252281 Levy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania);  The Trustee of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Richard J. Levy (New York City, New York);  Clifford S. Deutschman (Narberth, Pennsylvania)
ABSTRACT Methods for the treatment of sepsis related cardiac dysfunction are disclosed.
FILED Tuesday, February 14, 2006
APPL NO 11/816230
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/94.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252520 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Taivex Therapeutics Corporation (Taipei, Taiwan)
INVENTOR(S) Wen-Hwa Lee (Newport Coast, California);  Phang-Lang Chen (Irvine, California);  Yumay Chen (San Antonio, Texas)
ABSTRACT The present invention provides methods and compounds for inhibiting HEC1 activity for the treatment of diseases involving cell hyperproliferation, e.g. cancer. The present invention also provides methods of identifying compounds for inhibiting HEC1 activity.
FILED Tuesday, October 14, 2003
APPL NO 10/530274
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
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US 08252527 Sullivan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Amherst, New York)
INVENTOR(S) John M. Sullivan (Hamburg, New York);  Edwin H. Yau (Amherst, New York)
ABSTRACT Provided are methods for identifying a polynucleotide that can reduce the level of a target mRNA. The method can be performed by providing cells that express an RNA polynucleotide that contains a target mRNA sequence, an internal ribosome entry sequence (IRES) and a sequence encoding a secreted reporter protein; introducing to the cells a test polynucleotide, and measuring activity of the secreted reporter protein. A reduction in secreted reporter protein activity relative to a control cell into which the test polynucleotide has not been introduced is indicative that the test polynucleotide is capable of reducing the level of the target mRNA in the cells. The method is adaptable for high throughput screening methods and is suited for identifying polynucleotides that can catalyze cleavage of target mRNA and/or act on target mRNA through and antisense or RNAi mechanism.
FILED Tuesday, February 19, 2008
APPL NO 12/070561
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 08252532 Peluso
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Connecticut (Farmington, Connecticut)
INVENTOR(S) John J. Peluso (Avon, Connecticut)
ABSTRACT A progesterone regulator capable of modulating the non-genomic action of progesterone and methods of using the progesterone regulator are described. The progesterone regulator is useful for attenuating progesterone's inhibition of apoptosis and for the treatment of patients having a progesterone-responsive tissue disease such as endometriosis or cancer, particularly ovarian cancer, as well as for diagnosis, prognosis, and/or staging of ovarian cancers.
FILED Wednesday, March 04, 2009
APPL NO 12/380789
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252534 Sommer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Steve S. Sommer (Duarte, California);  John J. Rossi (Alta Loma, California)
ABSTRACT A method of diagnosing, assessing susceptibility, and/or treating schizophrenia involving the identification and/or observation of microRNAs (miRNA) and variant miRNA are provided. Micro RNAs alleles associated with schizophrenia and schizophrenia spectrum disorders were identified and ultra-rare variants in the precursor or mature miRNA were identified. Functional analyses of ectopically expressed copies of the variant miRNA precursors demonstrate loss of function, gain of function and altered expression levels. The present invention also provides methods for selecting a preferred therapy for a particular subject or group of subjects or individuals at risk for or suffering from schizophrenia or psychosis by use of miRNAs.
FILED Friday, June 12, 2009
APPL NO 12/484145
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252538 Croce et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Ohio State University (Columbus, Ohio);  The United States of America as represented by the Secretary of the Department of Health and Human Services National Institute of Health, Office of Technology Transfer (Washington, District of Columbia);  Liver Cancer Institute and Zhongshan Hospital, Fudan University (Shangai, China PRC)
INVENTOR(S) Carlo M. Croce (Columbus, Ohio);  Xin W. Wang (Rockville, Maryland);  Anuradha Budhu (College Park, Maryland);  Zhao-you Tang (Shanghai, China PRC)
ABSTRACT Provided herein are methods and compositions for the diagnosis, prognosis and treatment of Hepatocellular carcinoma (HCC). Also provided are methods of identifying anti-HCC agents.
FILED Thursday, November 01, 2007
APPL NO 12/513219
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252545 Hwu et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Patrick Hwu (Houston, Texas);  Rejean LaPointe (Laval, Canada);  Steven A. Rosenberg (Potomac, Maryland);  Maria Parkhurst (Ellicott City, Maryland)
ABSTRACT Immunogenic peptides of a melanoma antigen recognized by T cells, designated gp100, bioassays using the peptides to diagnose, assess or prognose a mammal afflicted with cancer, more specifically melanoma or metastatic melanoma, and use of the proteins and peptides as immunogens to inhibit, prevent or treat melanoma.
FILED Wednesday, May 19, 2010
APPL NO 12/782858
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252546 Briles et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S) David E. Briles (Birmingham, Alabama);  Susan K. Hollingshead (Birmingham, Alabama)
ABSTRACT Compositions and methods for eliciting an immune response against Streptococcus pneumoniae are described. More particularly, the present disclosure relates to immunogenic PcpA polypeptides, including fragments of PcpA and variants thereof, and nucleic acids that encode the polypeptides. The present disclosure further relates to methods of making and using the immunogenic polypeptides. Further provided is a method of diagnosing pneumococcal infection (e.g., pneumonia) in a subject by obtaining a biological sample from the subject and detecting one or more pneumococcal antigens that are selectively expressed during invasion (e.g., PcpA or fragments thereof).
FILED Friday, August 17, 2007
APPL NO 12/377440
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.340
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252550 Otto et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Michael Otto (Hamilton, Montana);  Stanislava Kocianova (Worcester, Massachusetts);  Cuong Vuong (Worcester, Massachusetts);  Jovanka Voyich (Belgrade, Montana);  Yufeng Yao (Baltimore, Maryland);  Elizabeth Fischer (Hamilton, Montana);  Frank De Leo (Corvallis, Montana)
ABSTRACT Immunogenic compositions and methods for eliciting an immune response against S. epidermidis and other related staphylococci are provided. The immunogenic compositions can include immunogenic conjugates of poly-γ-glutamic acid (such as γDLPGA) polypeptides of S. epidermidis, or related staphylococci that express a γPGA polypeptide. The γPGA conjugates elicit an effective immune response against S. epidermidis, or other staphylococci, in subjects to which the conjugates are administered. A method of treating an infection caused by a Staphylococcus organism that expresses cap genes is also disclosed. The method can include selecting a subject who is at risk of or has been diagnosed with the infection by the Staphylococcus organism which expresses γPGA from the cap genes. Further, the expression of a γPGA polypeptide by the organism can then be altered.
FILED Friday, February 25, 2011
APPL NO 13/035716
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/36
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US 08252553 Höök et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Magnus Höök (Houston, Texas);  Xuejun Xu (Missouri, Connecticut);  Jiyeun Kim (San Francisco, California)
ABSTRACT The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising this novel sequence and the use of the peptides in enabling cell adhesion. Also provided herein are methods to identify specific integrin inhibitors, sequences of these inhibitors and their use in inhibiting pathophysiological conditions that may arise due to integrin-collagen interaction.
FILED Thursday, March 26, 2009
APPL NO 12/383746
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252574 Mason et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Peter W. Mason (Galveston, Texas);  Elena Frolova (Galveston, Texas);  Ilya Frolov (Galveston, Texas)
ABSTRACT The present invention discloses a replication-deficient pseudoinfective virus belonging to the Flaviviridae family that lack the capsid gene, where the replication-deficient pseudoinfective virus propagates only in cells expressing the capsid or capsid, prM and envelope protein of the flavivirus. The present also discloses the method of producing such viruses on a large scale and the use of these pseudoinfective viruses as vaccines for preventing diseases caused by infections of humans or animals by the viruses belonging to this family.
FILED Tuesday, February 27, 2007
APPL NO 11/711532
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/235.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252591 Ince et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  The Brigham and Women's Hospital (Boston, Massachusetts)
INVENTOR(S) Tan A. Ince (Brookline, Massachusetts);  Robert A. Weinberg (Brookline, Massachusetts)
ABSTRACT The invention provides tissue culture system for primary cells (e.g. normal mammalian primary epithelial progenitors). This system includes: a) a serum-free, chemically defined cell culture media; and, b) methods for isolation and in vitro long-term propagation of primary cells (e.g. primary epithelial cells). Primary cells so isolated and cultured can be kept undifferentiated and proliferate for many weeks (>15 weeks) or population doubling (>35 PD) without senescence, or any detectable genetic alterations. Upon changing media/culture conditions, these cells can be induced to differentiate. The invention also provides methods to transform normal primary cells so cultured into “cancer stem cells.” The genetically defined cancer stem cell tumor model mimics the behavior of the disease closely, e.g., the cells are invasive, hormone responsive and metastatic when injected into mice. The tumor cells express genes that are specific to cancer stem cells identified in patient samples.
FILED Friday, May 06, 2005
APPL NO 11/123612
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/405
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252595 Stowell Laurence et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Jennifer Ann Stowell Laurence (Lawrence, Kansas);  Anthony Andrew Vartia (Lawrence, Kansas);  Mary Elizabeth Krause (Lawrence, Kansas)
ABSTRACT Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
FILED Friday, March 23, 2012
APPL NO 13/429167
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/86
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252737 Hodges et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Robert S. Hodges (Denver, Colorado);  Yuxin Chen (Changchun, China PRC);  Michael Vasil (Centennial, Colorado);  Robert E. W. Hancock (Vancouver, Canada);  Susan W. Farmer (Vancouver, Canada)
ABSTRACT Disclosed herein are novel antimicrobial peptides with useful, improved, or superior properties such as antimicrobial activity, desirable levels of hemolytic activity, and therapeutic index against a broad range of microorganisms including gram-negative and gram-positive bacteria and other organisms having a cellular or structural component of a lipid bilayer membrane. Also provided are methods of making and using such peptides to control microbial growth and in pharmaceutical compositions for treatment or prevention of infections caused by such microorganisms. Certain peptides are disclosed utilizing a structure-based rational design relating to an antimicrobial peptide, V681, with single D-/L-amino acid substitutions or charged residue substitutions in or near the center of the peptide on the nonpolar or polar face. Also disclosed are peptides with one or more amino acids in the D configuration, including peptides with all amino acids in the D configuration. Modified peptide analogs herein can demonstrate one or more properties such as improved antimicrobial activity, specificity, and resistance to degradation. Compositions disclosed herein have useful clinical potential as antibiotics including broad spectrum antibiotics.
FILED Thursday, December 15, 2005
APPL NO 11/721915
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252754 Ambron et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Richard Ambron (Lake Success, New York);  Ying-Ju Sung (Prospect Park, New Jersey);  Donald W. Landry (New York, New York);  Shi-Xian Deng (White Plains, New York)
ABSTRACT The present invention relates to the discovery of a novel molecular pathway involved in long-term hyperexcitability of sensory neurons, which, in higher animals, is associated with persistent pain. It is based on the discovery that, following injury to an axon of a neuron, an increase in nitric oxide synthase activity results in increased nitric oxide production, which, in turn, activates guanylyl cyclase, thereby increasing levels of cGMP. Increased cGMP results in activation of protein kinase G (“PKG”), which then is retrogradely transported along the axon to the neuron cell body, where it phosphorylates MAPKerk.
FILED Tuesday, March 21, 2006
APPL NO 11/385455
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252764 Pasqualini et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Renata Pasqualini (Houston, Texas);  Wadih Arap (Houston, Texas);  Mikhail G. Kolonin (Houston, Texas)
ABSTRACT The present invention concerns compositions comprising and methods of identification and use of targeting peptides for placenta or adipose tissue. In certain embodiments, the targeting peptides comprise part or all of SEQ ID NO:5-11, SEQ ID NO:13-22 or SEQ ID NO:144. The peptides may be attached to various therapeutic agents for targeted delivery. Adipose-targeting peptides may be used in methods for weight control, inducing weight loss and treating lipodystrophy syndrome. Adipose-targeting may also be accomplished using other binding moieties selectively targeted to adipose receptors, such as a prohibition receptor protein complex. Placenta-targeting peptides may be used to interfere with pregnancy, induce labor and/or for targeted delivery of therapeutic agents to placenta and/or fetus. In other embodiments, receptors identified by binding to placenta-targeting peptides may be used to screen compounds for potential teratogenicity. An exemplary placental receptor is FcRn/β2M, and compounds that bind to FcRn/β2M are potential teratogens.
FILED Monday, April 11, 2011
APPL NO 13/084328
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252767 Thompson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)
ASSIGNEE(S) Dogwood Pharmaceuticals, Inc. (Charlottesville, Virginia)
INVENTOR(S) Robert Thompson (Charlottesville, Virginia);  Anthony Beauglehole (Charlottesville, Virginia);  Frank Schmidtmann (Charlottesville, Virginia);  Jayson Rieger (Charlottesville, Virginia)
ABSTRACT The present invention provides substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters and pharmaceutical compositions containing the same that are selective agonists of A2A adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
FILED Saturday, December 20, 2008
APPL NO 12/809381
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/46
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252775 Kanter et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California);  U.S. Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Jennifer L. Kanter (Boston, Massachusetts);  William H. Robinson (Palo Alto, California);  Lawrence Steinman (Stanford, California)
ABSTRACT To perform large-scale multiplex analysis of lipid-specific binding, lipid microarrays were developed. Lipids identified as disease associated, or analogs there, can be tolerogenic to patients suffering from autoimmune disease. Lipid array analysis has revealed anti-lipid antibodies in patients with immune disorders, and may contribute to the pathogenesis of disease.
FILED Friday, July 21, 2006
APPL NO 11/491409
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/109
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252778 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Yihua Yu (Ellicott City, Maryland);  Zhong-Xing Jiang (Dundalk, Maryland)
ABSTRACT Disclosed are compounds comprising the structure:
In one aspect, the compounds exhibit maximum symmetric branching. Also disclosed are bilayers, micelles, coatings, and nanoparticles comprising the disclosed compounds. Also disclosed are processes for the preparation of the disclosed compounds and methods of using the disclosed compounds. Also disclosed are highly fluorinated dendrons and methods for making same. Also disclosed are methods for Fluorous Mixture Synthesis and tagging. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Monday, March 26, 2007
APPL NO 12/294424
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/183
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252804 Gangjee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania);  Wayne State University (Detroit, Michigan)
INVENTOR(S) Aleem Gangjee (Allison Park, Pennsylvania);  Larry H. Matherly (Farmington Hills, Michigan)
ABSTRACT Fused cyclic pyrimidine compounds, including tautomers thereof, and pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, are disclosed having the general Formula I:
These compounds are useful in methods for treating cancer, selectively targeting cancerous cells via the proton coupled folate transporter, folate receptor alpha, and/or folate receptor beta pathways, inhibiting GARFTase in cancerous cells, and selectively targeting activated macrophages in a patient having an autoimmune disease, such as rheumatoid arthritis.
FILED Wednesday, October 01, 2008
APPL NO 12/242988
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/265.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252834 Baker, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) James R. Baker, Jr. (Ann Arbor, Michigan);  Xue-min Cheng (Ann Arbor, Michigan);  Thommey P. Thomas (Dexter, Michigan);  Baohua Mark Huang (Ann Arbor, Michigan)
ABSTRACT The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer-linker conjugates, methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer-linker conjugates of the present invention may further comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy.
FILED Thursday, March 12, 2009
APPL NO 12/403179
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/412
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252841 Sperandio et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas);  OMM Scientific Inc. (Dallas, Texas)
INVENTOR(S) Vanessa Sperandio (Flower Mound, Texas);  John R. Falck (Dallas, Texas);  Donald R. Stewart (Fort Worth, Texas)
ABSTRACT The present invention relates to compounds and methods for the treatment of bacterial infections. Because their mechanism of action does not involve killing of bacteria or inhibiting their growth, the potential for these compounds to induce drug resistance in bacteria is minimized. Through inhibiting bacterial virulence, the present invention provides a novel means of treating bacterial infections.
FILED Monday, October 20, 2008
APPL NO 12/254690
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/586
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252846 Murthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia);  University of Rochester (Rochester, New York)
INVENTOR(S) Niren Murthy (Atlanta, Georgia);  Bali Pulendran (Alpharetta, Georgia);  Robert H. Pierce (Palo Alto, California);  Michael John Heffernan (Atlanta, Georgia);  Jihua Hao (Cleveland, Ohio);  Marcin Kwissa (Atlanta, Georgia);  Michael Davis (Atlanta, Georgia);  Stephen C. Yang (Mableton, Georgia)
ABSTRACT The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles.
FILED Wednesday, March 12, 2008
APPL NO 12/075667
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/772.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252893 Kim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S) Kevin H. Kim (Little Rock, Arkansas);  Mayumi Nakagawa (Little Rock, Arkansas);  Anna-Barbara Moscicki (San Francisco, California)
ABSTRACT The present invention is directed to the examination of the pattern of immunodominant CD8 T cell epitopes in the E6 and E7 protein of Human Papillomavirus (HPV) and its further characterization in terms of its amino acid sequence and HLA restriction. These epitopes are identified based on their ability to induce strong CD8 T cell response and therefore, are important as sources of antigens for dendritic cell immunotherapy to treat cervical cancer. The present invention contemplates identifying a number of similar epitopes restricted by a wide variety of HLA types so that they can be used in concert to develop a preventative vaccine, which can be used for general population.
FILED Tuesday, January 31, 2006
APPL NO 11/343606
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252894 Pier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Gerald B. Pier (Brookline, Massachusetts);  Casie Anne Kelly-Quintos (Jamaica Plain, Massachusetts);  Lisa Cavacini (Natick, Massachusetts);  Marshall R. Posner (Medfield, Massachusetts)
ABSTRACT The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically to poly-N-acetyl glucosamine (PNAG), such as Staphylococcal PNAG, in acetylated, partially acetylated and/or fully deacetylated form. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy of infections by bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Some antibodies of the invention enhance opsonophagocytic killing and in vivo protection against bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides.
FILED Monday, May 09, 2011
APPL NO 13/103532
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252899 Stevens et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Raymond C. Stevens (La Jolla, California);  Michael A. Hanson (San Marcos, California);  Vadim Cherezov (San Diego, California);  Peter Kuhn (Solana Beach, California)
ABSTRACT The invention describes compositions and method useful for the crystallization of membrane proteins.
FILED Wednesday, October 22, 2008
APPL NO 12/739134
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252902 Barbas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Carlos F. Barbas (Solana Beach, California);  Christoph Rader (San Diego, California);  Subhash C. Sinha (San Diego, California);  Richard A. Lerner (La Jolla, California)
ABSTRACT The present invention provides antibody targeting compounds in which the specificity of the antibody has been reprogrammed by covalently or noncovalently linking a targeting agent to the combining site of an antibody. By this approach, the covalently modified antibody takes on the binding specificity of the targeting agent. The compound may have biological activity provided by the targeting agent or by a separate biological agent. Various uses of the invention compounds are provided.
FILED Tuesday, October 22, 2002
APPL NO 10/278364
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252909 Tsuji et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York);  The Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) Moriya Tsuji (New York, New York);  Guangwu Chen (Corona, New York);  Richard Franck (Riverside, Connecticut);  Guangli Yang (Brooklyn, New York)
ABSTRACT The invention is directed to compounds of formula (I)
wherein X is O or NH; R′ is a hydrocarbon chain; R3 and R4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q′ is optionally present and may be a C1-10 hydrocarbon; X′ is optionally present and may be O, S or NR8; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
FILED Friday, July 29, 2005
APPL NO 11/193852
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Organic compounds
536/1.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252914 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Tong Zhang (Lebanon, New Hampshire);  Charles L. Sentman (West Lebanon, New Hampshire)
ABSTRACT The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.
FILED Wednesday, June 08, 2011
APPL NO 13/155909
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252929 Wentland
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Mark P. Wentland (Watervliet, New York)
ABSTRACT 8-Substituted-2,6-methano-3-benzazocines of general structure I in which A is —CH2—OH, —CH2NH2, —NHSO2CH3,
and Y is O, S or NOH are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications.
8-Carboxamides, thiocarboxamides, hydroxyamidines and formamides are preferred.
FILED Monday, May 09, 2011
APPL NO 13/103599
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/45
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252940 Felise et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Heather B. Felise (Lynnwood, Washington);  Samuel I. Miller (Seattle, Washington);  Toni Kline (Seattle, Washington)
ABSTRACT A method for inhibiting Gram-negative bacterial pathogenesis, a method of screening for compounds that inhibit type III secretion in Gram-negative bacteria, and compounds that inhibit type III secretion in Gram-negative bacteria.
FILED Monday, August 16, 2010
APPL NO 12/856986
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/184
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252941 Momiyama et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) Japan Science and Technology Agency (Saitama, Japan)
INVENTOR(S) Norie Momiyama (Sendai, Japan);  Hiromi Torii (Kariya, Japan);  Susumu Saito (Nagoya, Japan);  Hisashi Yamamoto (Chicago, Illinois);  Yuhei Yamamoto (Tsukuba, Japan)
ABSTRACT The present invention is directed to a process of making α-aminooxyketone and α-hydroxyketone compounds. The synthetic pathway generally involves reacting an aldehyde or ketone substrate and a nitroso substrate in the presence of a catalyst of the formula (IV):
wherein Xa—Xc represent independently nitrogen, carbon, oxygen or sulfur and Z represents a 4 to 10-membered ring with or without a substituent and optionally a further step to convert the α-aminooxyketone compound formed to the α-hydroxyketone compound. The present invention results in α-aminooxyketone and α-hydroxyketone compounds with high enantioselectivity and high purity. The present invention is also directed to a catalytic asymmetric O-nitroso Aldol/Michael reaction. The substrates of this reaction are generally cyclic α,β-unsaturated ketone substrate and a nitroso substrate. This methodology generally involves reacting the cyclic α,β-unsaturated ketone substrate and the nitroso substrate in the presence of a proline-based catalyst, to provide a heterocyclic product.
FILED Wednesday, October 14, 2009
APPL NO 12/578836
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
548/250
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253626 Schantz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institute for Occupational Safety and Health (NIOSH)
APPLICANT(S)
ASSIGNEE(S) Q-Track Corporation (Huntsville, Alabama)
INVENTOR(S) Hans Gregory Schantz (Huntsville, Alabama);  Andrew Compston (Stanford, California);  Robert DePierre (Huntsville, Alabama);  James Matthew Barron (Huntsville, Alabama)
ABSTRACT A multiple phase state near-field electromagnetic location and communication system includes a multiple phase state near-field transmitter, and a near-field locator receiver. The near-field transmitter is capable of operation in at least two states and each of these at least two states generates a state characteristic difference detected at the near-field locator receiver. The state characteristic difference may be employed for location determination, communication or both. The present invention is particularly well-suited for use in conjunction with a near-field electromagnetic ranging system. In further embodiments, a multiple phase state near-field electromagnetic location and communication process includes the steps of determining a transmission state for a near-field quadrature transmitter, transmitting a near-field transmission corresponding to said transmission state, receiving a near-field transmission corresponding to said transmission state, and determining a difference between at least two properties of said near-field transmission where the difference is characteristic of and corresponding to the transmission state.
FILED Monday, February 23, 2009
APPL NO 12/391209
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications: Directive radio wave systems and devices
342/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254020 Holy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Timothy E. Holy (St. Louis, Missouri);  Terrence F. Holekamp (St. Louis, Missouri)
ABSTRACT A microscope assembly includes an illumination source coupled to an optical assembly by a coupler. The optical assembly includes an objective with optics that move along an optic axis. The illumination source generates a light blade that illuminates a portion of a sample at an illumination plane. The light blade induces a fluorescent emission from the sample that is projected through the objective optics to a detector. The focal plane of the objective optics is fixed with respect to the illumination source by the coupler so that the illumination plane is coincident with the focal plane as the objective optics move along the optic axis. The objective and illumination may be rapidly scanned along the optic axis to provide rapid three-dimensional imaging while the objective and illumination may also be rapidly scanned along the optic axis to provide rapid three-dimensional imaging.
FILED Friday, April 20, 2007
APPL NO 12/297716
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/385
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254654 Yen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Jesse T. Yen (San Gabriel, California);  Chi Hyung Seo (Issaquah, Washington)
ABSTRACT Sidelobe and clutter suppression techniques in ultrasound imaging are described and referred to as Dual Apodization with Cross-correlation or “DAX”. DAX dramatically improves the contrast-to-noise ratio (CNR) allowing for easier visualization of anechoic cysts and blood vessels. These techniques use dual apodization or weighting strategies that are effective in removing or minimizing clutter and efficient in terms of computational load and hardware/software needs. This dual apodization allows for determination of the amount of mainlobe versus clutter contribution in a signal by cross-correlating RF data acquired from two apodization functions.
FILED Thursday, October 30, 2008
APPL NO 12/261922
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Image analysis
382/131
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE43612 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Research Service Award (NRSA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniel Griffith Anderson (Sudbury, Massachusetts);  David M. Lynn (Middleton, Wisconsin);  Akin Akinc (Needham, Massachusetts);  Robert S. Langer (Newton, Massachusetts)
ABSTRACT Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. A system for preparing and screening polymers in parallel using semi-automated robotic fluid delivery systems is also provided.
FILED Monday, September 28, 2009
APPL NO 12/568481
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/78.370
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE43615 Toenjes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Montana State University Billings (Billings, Montana)
INVENTOR(S) Kurt A. Toenjes (Billings, Montana);  David K. Butler (Billings, Montana)
ABSTRACT A method for controlling yeast-to-filamentous growth transition in fungi comprising contacting a fungal cell with an anti-fungal small molecule in an amount effective to reduce or inhibit the yeast-to-filamentous growth transition, wherein the anti-fungal small molecule is 5-(p-Bromobenzylidine)-α-isopropyl-4-oxo-2-thioxo-3-thiozolidineacetic acid or an analog thereof. A method for treating fungal infections comprising contacting one or more fungal cells with an anti-fungal small molecule in an amount effective to control the fungal infection, wherein the anti-fungal small molecule is 5-(p-Bromobenzylidine)-α-isopropyl-4-oxo-2-thioxo-3-thiozolidineactic acid or an analog thereof.
FILED Wednesday, January 25, 2012
APPL NO 13/358512
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/369
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 08250992 Swygert
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Richard W. Swygert (Springfield, South Carolina)
ABSTRACT A ladder attachment platform is provided that includes a base for attachment to a ladder that has first and second side rails and a plurality of rungs that extend between in a lateral direction. Also included is a user platform for having a user stand thereon that is carried by the base. The user platform may be positioned with respect to the ladder so that it is not located between a first plane that extends through the first side rail and is perpendicular to the lateral direction and a second plane that extends through the second side rail and is perpendicular to the lateral direction.
FILED Thursday, April 29, 2010
APPL NO 12/799648
ART UNIT 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Railway rolling stock
15/425
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251016 Boxley et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)
ASSIGNEE(S) Ceramatec, Inc. (Salt Lake City, Utah)
INVENTOR(S) Chett Boxley (Park City, Utah);  Jessica McKelvie (Sandy, Utah)
ABSTRACT An animal litter composition including geopolymerized ash particulates having a network of repeating aluminum-silicon units is described herein. Generally, the animal litter is made from a quantity of a pozzolanic ash mixed with a sufficient quantity of water and an alkaline activator to initiate a geopolymerization reaction that forms geopolymerized ash. After the geopolymerized ash is formed, it is dried, broken into particulates, and sieved to a desired size. These geopolymerized ash particulates are used to make a non-clumping or clumping animal litter. Odor control is accomplished with the addition of a urease inhibitor, pH buffer, an odor eliminating agent, and/or fragrance.
FILED Tuesday, September 14, 2010
APPL NO 12/881994
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Animal husbandry
119/173
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251652 Campbell et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) Christian X. Campbell (Oviedo, Florida);  Anthony L. Schiavo (Oviedo, Florida);  Jay A. Morrison (Oviedo, Florida)
ABSTRACT A gas turbine CMC shroud plate (48A) with a vane-receiving opening (79) that matches a cross-section profile of a turbine vane airfoil (22). The shroud plate (48A) has first and second curved circumferential sides (73A, 74A) that generally follow the curves of respective first and second curved sides (81, 82) of the vane-receiving opening. Walls (75A, 76A, 77A, 78A, 80, 88) extend perpendicularly from the shroud plate forming a cross-bracing structure for the shroud plate. A vane (22) may be attached to the shroud plate by pins (83) or by hoop-tension rings (106) that clamp tabs (103) of the shroud plate against bosses (105) of the vane. A circular array (20) of shroud plates (48A) may be assembled to form a vane shroud ring in which adjacent shroud plates are separated by compressible ceramic seals (93).
FILED Friday, June 05, 2009
APPL NO 12/479082
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/209.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251658 Diggs et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S) William B Diggs (West Palm Beach, Florida);  Keith D Kimmel (Jupiter, Florida)
ABSTRACT A turbine rotor blade with a spar and shell construction, and a tip cap that includes a row of teeth and slots extending from a bottom side that engage with similar shaped teeth and slots on a tip end of the spar to secure the tip cap to the spar against radial displacement. The tooth on the trailing edge end of the tip cap is aligned perpendicular to the pressure side wall of the blade in the trailing edge region in order to minimize stress due to the teeth wanting to bend under high centrifugal loads. To reduce stress, some of the teeth include a cutback to shorten the teeth in places where high stress levels would occur.
FILED Tuesday, December 08, 2009
APPL NO 12/633314
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/62
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252077 Gonze et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations LLC (, None)
INVENTOR(S) Eugene V. Gonze (Pinckney, Michigan);  Michael J. Paratore, Jr. (Howell, Michigan);  Kevin W. Kirby (Calabasas Hills, California);  Amanda Phelps (Malibu, California)
ABSTRACT A system includes a particulate matter (PM) filter that includes an upstream end for receiving exhaust gas and a downstream end. A zoned resistive heater is arranged spaced from said upstream end and includes N zones, where N is an integer greater than one, wherein each of the N zones includes M sub-zones, where M is an integer greater than or equal to one, and wherein the zoned heater includes an electrically insulating material. A control module selectively activates at least a selected one of the N zones to initiate regeneration in downstream portions of the PM filter from the one of the N zones and deactivates non-selected ones of the N zones.
FILED Friday, November 02, 2007
APPL NO 11/934256
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Gas separation
055/282.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252186 Blake et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S)
ASSIGNEE(S) The Administrators of the Tulane Educational Fund (New Orleans, Louisiana)
INVENTOR(S) Diane A. Blake (Mandeville, Louisiana);  Nurettin Sahiner (Canakkale, Turkey)
ABSTRACT Novel compositions of matter synthesized from acrylonitrile and crosslinker, and subsequently coated with various hydrophilic monomers, can be used in the remediation of uranyl ions from groundwater, drinking water, or wastewater and as part of a system for measurement of uranium in environmental and biological samples.
FILED Thursday, November 20, 2008
APPL NO 12/274976
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/681
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252191 Heejoon et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Dow Corning Corporation (Midland, Michigan)
INVENTOR(S) Ahn Heejoon (Seoul, South Korea);  Ralph Nuzzo (Champaign, Illinois);  Anne Shim (Plaistow, New Hampshire)
ABSTRACT The present invention provides a method of sub-micron decal transfer lithography. The method includes forming a first pattern in a surface of a first silicon-containing elastomer, bonding at least a portion of the first pattern to a substrate, and etching a portion of at least one of the first silicon-containing elastomer and the substrate.
FILED Friday, May 05, 2006
APPL NO 11/911787
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Etching a substrate: Processes
216/43
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US 08252223 Medina et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas);  Sandia Corporation, Operator of Sandia National Laboratories (Albuquerque, New Mexico)
INVENTOR(S) Francisco Medina (El Paso, Texas);  Ryan Wicker (El Paso, Texas);  Jeremy A. Palmer (Albuquerque, New Mexico);  Don W. Davis (Albuquerque, New Mexico);  Bart D. Chavez (Albuquerque, New Mexico);  Phillip L. Gallegos (Albuquerque, New Mexico)
ABSTRACT An integrated system and method of integrating fluid dispensing technologies (e.g., direct-write (DW)) with rapid prototyping (RP) technologies (e.g., stereolithography (SL)) without part registration comprising: an SL apparatus and a fluid dispensing apparatus further comprising a translation mechanism adapted to translate the fluid dispensing apparatus along the Z-, Y- and Z-axes. The fluid dispensing apparatus comprises: a pressurized fluid container; a valve mechanism adapted to control the flow of fluid from the pressurized fluid container; and a dispensing nozzle adapted to deposit the fluid in a desired location. To aid in calibration, the integrated system includes a laser sensor and a mechanical switch. The method further comprises building a second part layer on top of the fluid deposits and optionally accommodating multi-layered circuitry by incorporating a connector trace. Thus, the present invention is capable of efficiently building single and multi-material SL fabricated parts embedded with complex three-dimensional circuitry using DW.
FILED Wednesday, December 23, 2009
APPL NO 12/646632
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/401
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252338 Forte et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Children's Hospital and Research Center Oakland (Oakland, California)
INVENTOR(S) Trudy M. Forte (Berkeley, California);  Mina Nikanjam (Richmond, California)
ABSTRACT The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so as to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of incorporating and targeting therapeutics to cells expressing the LDL receptor for diseases associated with the expression of the LDL receptor such as central nervous system diseases. The invention further provides methods of using such synthetic LDL nanoparticles.
FILED Monday, November 13, 2006
APPL NO 12/084845
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/499
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US 08252561 Das et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Keshav C. Das (Athens, Georgia);  Senthil Chinnasamy (Tamilnadu, India);  James Shelton (Athens, Georgia);  Susan B. Wilde (Watkinsville, Georgia);  Rebecca S. Haynie (Carlton, Georgia);  James A. Herrin (Atlanta, Georgia)
ABSTRACT Embodiments of the present disclosure provide for novel strategies to harvest algal lipids using mollusks which after feeding algae from the growth medium can convert algal lipids into their biomass or excrete lipids in their pseudofeces which makes algae harvesting energy efficient and cost effective. The bioconverter, filter-feeding mollusks and their pseudofeces can be harvested and converted to biocrude using an advanced thermochemical liquefaction technology. Methods, systems, and materials are disclosed for the harvest and isolation of algal lipids from the mollusks, molluscan feces and molluscan pseudofeces.
FILED Tuesday, August 24, 2010
APPL NO 12/862246
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/134
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US 08252613 Lyons et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Robert Joseph Lyons (Burnt Hills, New York);  Anant Achyut Setlur (Niskayuna, New York);  Anirudha Rajendra Deshpande (Twinsburg, Ohio);  Ljudmil Slavchev Grigorov (Sofia, Bulgaria)
ABSTRACT A process for preparing color stable Mn+4 doped phosphors includes providing a phosphor of formula I;
Ax[MFy]:Mn+4  I
and contacting the phosphor in particulate form with a saturated solution of a composition of formula II in aqueous hydrofluoric acid;
Ax[MFy];  II wherein A is Li, Na, K, Rb, Cs, NR4 or a combination thereof; M is Si, Ge, Sn, Ti, Zr, Al, Ga, In, Sc, Y, La, Nb, Ta, Bi, Gd, or a combination thereof; R is H, lower alkyl, or a combination thereof; x is the absolute value of the charge of the [MFy] ion; and y is 5, 6 or 7.
In particular embodiments, M is Si, Ge, Sn, Ti, Zr, or a combination thereof. A lighting apparatus capable of emitting white light includes a semiconductor light source; and a phosphor composition radiationally coupled to the light source, and which includes a color stable Mn+4 doped phosphor.
FILED Wednesday, March 23, 2011
APPL NO 13/069756
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/46
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US 08253012 Gessert et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Timothy A. Gessert (Conifer, Colorado);  Joel N. Duenow (Golden, Colorado);  Teresa Barnes (Evergreen, Colorado);  Timothy J. Coutts (Golden, Colorado)
ABSTRACT A transparent conducting oxide (TCO) film comprising: a TCO layer, and dopants selected from the elements consisting of Vanadium, Molybdenum, Tantalum, Niobium, Antimony, Titanium, Zirconium, and Hafnium, wherein the elements are n-type dopants; and wherein the transparent conducting oxide is characterized by an improved electron mobility of about 42 cm2/V-sec while simultaneously maintaining a high carrier density of ˜4.4e×1020 cm−3.
FILED Monday, March 17, 2008
APPL NO 12/441707
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/256
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US 08253802 Anderson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Robert J. Anderson (Albuquerque, New Mexico);  Fredrick Rothganger (Albuquerque, New Mexico)
ABSTRACT A technique for computer vision uses a polygon contour to trace an object. The technique includes rendering a polygon contour superimposed over a first frame of image data. The polygon contour is iteratively refined to more accurately trace the object within the first frame after each iteration. The refinement includes computing image energies along lengths of contour lines of the polygon contour and adjusting positions of the contour lines based at least in part on the image energies.
FILED Tuesday, September 01, 2009
APPL NO 12/551894
ART UNIT 2456 — Computer Networks
CURRENT CPC
Television
348/169
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US 08255633 Boyle et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Peter Boyle (Edinburgh, United Kingdom);  Norman Christ (Irvington, New York);  Alan Gara (Yorktown Heights, New York);  Changhoan Kim (San Jose, California);  Robert Mawhinney (New York, New York);  Martin Ohmacht (Yorktown Heights, New York);  Krishnan Sugavanam (Yorktown Heights, New York)
ABSTRACT A list prefetch engine improves a performance of a parallel computing system. The list prefetch engine receives a current cache miss address. The list prefetch engine evaluates whether the current cache miss address is valid. If the current cache miss address is valid, the list prefetch engine compares the current cache miss address and a list address. A list address represents an address in a list. A list describes an arbitrary sequence of prior cache miss addresses. The prefetch engine prefetches data according to the list, if there is a match between the current cache miss address and the list address.
FILED Friday, January 29, 2010
APPL NO 12/696825
ART UNIT 2185 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/137
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US 08255884 Eichenberger et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Alexandre E. Eichenberger (Chappaqua, New York);  Michael K. Gschwind (Chappaqua, New York);  John A. Gunnels (Yorktown Heights, New York)
ABSTRACT Mechanisms for optimizing scalar code executed on a single instruction multiple data (SIMD) engine are provided. Placement of vector operation-splat operations may be determined based on an identification of scalar and SIMD operations in an original code representation. The original code representation may be modified to insert the vector operation-splat operations based on the determined placement of vector operation-splat operations to generate a first modified code representation. Placement of separate splat operations may be determined based on identification of scalar and SIMD operations in the first modified code representation. The first modified code representation may be modified to insert or delete separate splat operations based on the determined placement of the separate splat operations to generate a second modified code representation. SIMD code may be output based on the second modified code representation for execution by the SIMD engine.
FILED Friday, June 06, 2008
APPL NO 12/134495
ART UNIT 2198 — Semiconductors/Memory
CURRENT CPC
Data processing: Software development, installation, and management
717/136
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08250863 Bollinger et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)
ASSIGNEE(S) SustainX, Inc. (Seabrook, New Hampshire)
INVENTOR(S) Benjamin R. Bollinger (Windsor, Vermont);  Troy O. McBride (Norwich, Vermont);  Benjamin Cameron (Hanover, New Hampshire);  Patrick Magari (Plainfield, New Hampshire);  Michael Izenson (Hanover, New Hampshire);  Weibo Chen (Hanover, New Hampshire)
ABSTRACT In various embodiments, compressed-gas energy storage and recovery systems include a cylinder assembly for compression and/or expansion of gas, a reservoir for storage and/or supply of compressed gas, and a system for thermally conditioning gas within the reservoir.
FILED Wednesday, April 27, 2011
APPL NO 13/094960
ART UNIT 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/511
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US 08252209 Raymo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) The University of Miami (Miami, Florida)
INVENTOR(S) Francisco M. Raymo (Coral Gable, Florida);  Massimiliano Tomasulo (Miami, Florida)
ABSTRACT We have designed a molecular switch based on the photoinduced opening and thermal closing of a [1,3]oxazine ring. A substituted [1,3]oxazine compound described as having a general (i.e., unsubstituted) structure with fused indoline and benzooxazine fragments such that they share a common bond in the [1,3]oxazine compound: (i) the bond connecting positions 1 and 2 of the indoline fragment and (ii) the bond connecting positions 2 and 3 of the benzooxazine fragment. Irradiation by light of suitable wavelength and intensity of this photochromic compound induces cleavage of a [C—O] bond of the [1,3]oxazine ring to form a phenolate chromophore. The photogenerated (e.g., colored) isomer may revert thermally to the starting (e.g., colorless) oxazine. Alternatively, the switch may be between isomers of the compound that absorb at different wavelengths. Reversible coloration of silica or polymeric materials and switching optical signals may involve many cycles of interconversion between different colored states. A colorless/colored state may be maintained by constant irradiation or chemical trapping.
FILED Friday, August 06, 2010
APPL NO 12/805579
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions
252/586
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US 08252539 Quake et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Stephen R. Quake (Pasadena, California);  Todd Thorsen (Pasadena, California)
ABSTRACT A microfluidic device for analyzing and/or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for its use are provided. The device and methods of the invention are useful for sorting particles, e.g. virions. The invention is also useful for high throughput screening, e.g. combinatorial screening. The microfluidic device comprises a main channel and an inlet region in communication with the main channel at a droplet extrusion region. Droplets of solution containing the biological material are deposited into the main channel through the droplet extrusion region. A fluid different from and incompatible with the solution containing the biological material flows through the main channel so that the droplets containing the biological material do not diffuse or mix. Biological material within the droplets can be analyzed and/or sorted by detecting a predetermined characteristic of the biological sample in each droplet and sorting the droplet accordingly.
FILED Monday, October 08, 2007
APPL NO 11/868942
ART UNIT 1775 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.120
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252598 Koley et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Goutam Koley (Columbia, South Carolina);  Muhammad Qazi (Columbia, South Carolina);  Thomas Vogt (Chapin, South Carolina);  Sangmoon Park (Busan, South Korea)
ABSTRACT Methods and systems of detecting analytes using a microcantilever system are generally described. The microcantilever system generally includes micro- or nano-sized elements that can be electrostatically driven to resonance. Utilizing the disclosed devices and methods, direct electronic detection of the resonant frequency, changes of the resonant frequency, and associated phase signal of a micro- or nano-sized element can be utilized to measure the presence of a targeted analyte. The detection system of the present invention utilizes a non-contact microcantilever device. That is, the surface of the microcantilever (e.g., the surface of the resonating beam) does not bond or otherwise attach to an analyte or other chemical. Thus, the microcantilever device, including the resonating beam, can be kept in pristine condition during and even after repeated use.
FILED Tuesday, November 27, 2007
APPL NO 12/442954
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/149
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252756 Mirkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
Nanoscale Science and Engineering Centers (NSF-NSEC)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chad A. Mirkin (Wilmette, Illinois);  Nathaniel L. Rosi (Pittsburgh, Pennsylvania);  C. Shad Thaxton (Chicago, Illinois);  David A. Giljohann (Chicago, Illinois)
ABSTRACT Materials and methods for regulating gene expression using nanoparticles functionalized with antisense oligonucleotides are provided.
FILED Thursday, June 08, 2006
APPL NO 11/917680
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252880 Matyjaszewski et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania);  Ke Min (Berkeley, California);  James Spanswick (Wheaton, Illinois)
ABSTRACT The present disclosure describes a two-step batch dispersion polymerization process for the preparation of substantially uniformed-sized functional (co)polymer particles. The first step of the process includes polymerizing at least one first radically (co)polymerizable monomer by a free radical polymerization process to form a (co)polymer in a stable colloidal dispersion and the second step includes polymerizing the at first radically (co)polymerizable monomer or an additional radically (co)polymerizable monomer in the stable colloidal dispersion by a living/controlled radical (co)polymerization process.
FILED Friday, May 23, 2008
APPL NO 12/451581
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
526/336
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252973 Pojer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S) The Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Florence Pojer (Del Mar, California);  Joseph P. Noel (San Diego, California);  Elise Larsen (Alpine, California);  Marianne Bowman (San Diego, California);  Stephane Richard (Del Mar, California)
ABSTRACT CHI like fatty acid binding proteins and genes, recombinant cells and organisms, methods of metabolic pathway engineering to improve lipid production in cells, Crystal structures of CHI like fatty acid binding proteins, methods of engineering CHI like fatty acid binding proteins and systems thereof are provided.
FILED Friday, May 13, 2011
APPL NO 13/107558
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/281
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US 08254242 Morelli et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Princeton University (Princeton, New Jersey)
INVENTOR(S) Michele Morelli (Fornacette, Italy);  H. Vincent Poor (Princeton, New Jersey);  Luca Sanguinetti (Pisa, Italy)
ABSTRACT A system and method for initial ranging in wireless communication systems is provided. A plurality of orthogonal frequency division multiplexing (OFDM) blocks are received by an OFDMA base station transceiver from a plurality of remote user devices in wireless communication with the base station. A ranging subchannel is extracted from the OFDM blocks. The number of active codes in the ranging subchannel is determined, active codes are identified, and carrier frequency offsets (CFOs) are estimated for each active code. Timing delays and power levels for each active code are then estimated. The estimated CFOs, timing delays, and power levels are broadcasted by the base station to the remote user devices, so that the user devices can utilize same to adjust transmission parameters to optimize power levels and synchronize communication with the base station.
FILED Friday, May 02, 2008
APPL NO 12/114220
ART UNIT 2478 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/203
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08254633 Moon et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) VideoMining Corporation (State College, Pennsylvania)
INVENTOR(S) Hankyu Moon (State Collage, Pennsylvania);  Rajeev Sharma (State College, Pennsylvania);  Namsoon Jung (State College, California)
ABSTRACT The present invention is a method and system to provide correspondences between a face camera track and a behavior camera track, for the purpose of making correspondence between the data obtained from each track. First, multiple learning machines are trained so that each of the machines processes pairwise person images from a specific pose region, and estimates the likelihood of two person images belonging to the same person based on image appearances. Then, the system acquires a person image associated with a behavior camera track, determines the pose of the person image based on its floor position, and corrects the pose of the person image. The system also acquires person images from face camera images associated with a face camera track, and combines the images with corrected person images from the previous step to form pairwise person images. The pairwise person image is fed to the trained pose-dependent pairwise person verification machines according to the pose of the person images, to compute the appearance match scores between the pair of person images. Finally, the combination of the appearance match scores and the spatiotemporal match scores of the pair of person images determines whether or not the person images belong to the same person.
FILED Tuesday, April 21, 2009
APPL NO 12/386656
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255061 Perlin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Gayatri Eadara Perlin (Ann Arbor, Michigan);  Brendan E. Casey (Ann Arbor, Michigan);  Mayurachat Ning Gulari (Ann Arbor, Michigan);  Kensall D. Wise (Ann Arbor, Michigan)
ABSTRACT A microsystem comprising a substrate having an aperture formed therethrough. The aperture includes a first cross-section and a second cross-section—the first cross-section being smaller than the second cross-section to define a ledge therebetween. A probe member is disposed within the aperture of the substrate, such that a backend of the probe member defines a cross-section that is greater than the first cross-section of the aperture and smaller than the second cross-section such that the probe member engages the ledge. A plurality of probe shanks extend from the probe member. Each of the probe shanks includes a plurality of leads disposed there along. Each of the leads extending from the probe shanks to an opposing side of the probe member.
FILED Tuesday, March 31, 2009
APPL NO 12/415177
ART UNIT 3739 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/116
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE43612 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Research Service Award (NRSA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniel Griffith Anderson (Sudbury, Massachusetts);  David M. Lynn (Middleton, Wisconsin);  Akin Akinc (Needham, Massachusetts);  Robert S. Langer (Newton, Massachusetts)
ABSTRACT Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. A system for preparing and screening polymers in parallel using semi-automated robotic fluid delivery systems is also provided.
FILED Monday, September 28, 2009
APPL NO 12/568481
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/78.370
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 08250901 Davis et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan);  Oceaneering International, Inc. (Webster, Texas)
INVENTOR(S) Donald R. Davis (Brighton, Michigan);  Frank Noble Permenter (Webster, Texas);  Nicolaus A Radford (Houston, Texas)
ABSTRACT A system includes a rotary device, a rotary absolute position (RAP) sensor generating encoded pairs of voltage signals describing positional data of the rotary device, a host machine, and an algorithm. The algorithm calculates calibration parameters usable to determine an absolute position of the rotary device using the encoded pairs, and is adapted for linearly-mapping an ellipse defined by the encoded pairs to thereby calculate the calibration parameters. A method of calibrating the RAP sensor includes measuring the rotary position as encoded pairs of voltage signals, linearly-mapping an ellipse defined by the encoded pairs to thereby calculate the calibration parameters, and calculating an absolute position of the rotary device using the calibration parameters. The calibration parameters include a positive definite matrix (A) and a center point (q) of the ellipse. The voltage signals may include an encoded sine and cosine of a rotary angle of the rotary device.
FILED Tuesday, September 22, 2009
APPL NO 12/564092
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/1.750
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08251312 Daso et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Endwell O. Daso (Madison, Alabama);  Victor E. Pritchett, II (Harvest, Alabama);  Ten-See Wang (Huntsville, Alabama);  Rebecca Ann Farr (Gurley, Alabama)
ABSTRACT The upstream flowfield of a vehicle traveling in supersonic or hypersonic atmospheric flight is actively controlled using attribute(s) experienced by the vehicle. Sensed attribute(s) include pressure along the vehicle's outer mold line, temperature along the vehicle's outer mold line, heat flux along the vehicle's outer mold line, and/or local acceleration response of the vehicle. A non-heated, non-plasma-producing gas is injected into an upstream flowfield of the vehicle from at least one surface location along the vehicle's outer mold line. The pressure of the gas so-injected is adjusted based on the attribute(s) so-sensed.
FILED Wednesday, September 09, 2009
APPL NO 12/555988
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252734 Schramm et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Harry F. Schramm (Winchester, Tennessee);  Frank G. Defalco (Houston, Texas);  Lloyd L. Starks, Sr. (Ooltewah, Texas)
ABSTRACT A process for creating conversion coatings and spin, drawing, and extrusion finishes for surfaces, wherein the conversion coatings and spin, drawing, and extrusion finishes contain potassium, phosphorus, nitrogen, silicon, and one or more non-alkaline metals. The process comprises forming a first aqueous solution of silicate, potassium hydroxide, and ammonium hydroxide; forming a second aqueous solution of water, phosphoric acid, ammonium hydroxide, an alkali metal hydroxide, and one or more non-alkaline metals, and then combining the first solution with the second solution to form a final solution. This final solution forms an anti-friction multi-layer conversion coating or a spin, drawing, and extrusion finish on a surface when applied to the surface, either directly or as an additive in lubricating fluids.
FILED Wednesday, December 09, 2009
APPL NO 12/634502
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Solid anti-friction devices, materials therefor, lubricant or separant compositions for moving solid surfaces, and miscellaneous mineral oil compositions
58/162
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255079 Linn et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan);  The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Douglas Martin Linn (White Lake, Michigan);  Chris A. Ihrke (Hartland, Michigan);  Myron A. Diftler (Houston, Texas)
ABSTRACT A grasp assist device includes a glove portion having phalange rings, contact sensors for measuring a grasping force applied by an operator wearing the glove portion, and a tendon drive system (TDS). The device has flexible tendons connected to the phalange rings for moving the rings in response to feedback signals from the sensors. The TDS is connected to each of the tendons, and applies an augmenting tensile force thereto via a microcontroller adapted for determining the augmenting tensile force as a function of the grasping force. A method of augmenting a grasping force of an operator includes measuring the grasping force using the sensors, encoding the grasping force as the feedback signals, and calculating the augmenting tensile force as a function of the feedback signals using the microcontroller. The method includes energizing at least one actuator of a tendon drive system (TDS) to thereby apply the augmenting tensile force.
FILED Tuesday, September 22, 2009
APPL NO 12/564095
ART UNIT 3651 — Material and Article Handling
CURRENT CPC
Data processing: Generic control systems or specific applications
7/213
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255732 Malekpour
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Mahyar R. Malekpour (Hampton, Virginia)
ABSTRACT Systems and methods for rapid Byzantine-fault-tolerant self-stabilizing clock synchronization are provided. The systems and methods are based on a protocol comprising a state machine and a set of monitors that execute once every local oscillator tick. The protocol is independent of specific application specific requirements. The faults are assumed to be arbitrary and/or malicious. All timing measures of variables are based on the node's local clock and thus no central clock or externally generated pulse is used. Instances of the protocol are shown to tolerate bursts of transient failures and deterministically converge with a linear convergence time with respect to the synchronization period as predicted.
FILED Friday, April 24, 2009
APPL NO 12/429603
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Support
713/400
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08254131 Babcock et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Raymond F. Babcock (Rochester, Minnesota);  Michael A. Boraas (Rochester, Minnesota)
ABSTRACT Carriage chassis for installation of a component assembly in a support structure. The support structure includes a power connector in a connector housing. The carriage chassis includes: rails adapted to receive a component assembly and a safety cover. One of the rails includes a tri-lobed torsion stop that includes a first lobe configured to contact the connector housing when no safety cover is installed, preventing a component assembly from coupling with power; a second lobe configured to receive contact from a displacement member of a safety cover, rotating the tri-lobed torsion stop; and a third lobe configured to provide contact to the displacement member when the safety cover is installed and a component assembly is coupled with power. The third lobe and the first lobe prevent removal of the safety cover when a component assembly is coupled with the power connector.
FILED Tuesday, June 15, 2010
APPL NO 12/815859
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/727
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255380 Christensen et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) James E. Christensen (Cortlandt Manor, New York);  Daniel M. Gruen (Newton, Massachusetts);  Susanne Hupfer (Lexington, Massachusetts);  Stephen E. Levy (Honolulu, Hawaii);  John F. Patterson (Carlisle, Massachusetts);  Jamie C. Rasmussen (Somerville, Massachusetts);  Steven I. Ross (South Hamilton, Massachusetts)
ABSTRACT An expertise locator enables user defined correspondences between experts and respective certain objects. Each object inherits from classes in a hierarchy. Using the correspondences, a locator processor routine finds a candidate expert about a particular subject area. The candidate expert may be in a correspondence with a certain object whose class is a subclass of the particular subject area. Output may display an indication of the candidate expert, relevant expertise per candidate and/or a list of experts per certain object. In the case of the certain objects being topics, the hierarchy is an ontology of the topics.
FILED Friday, December 18, 2009
APPL NO 12/642430
ART UNIT 2163 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/706
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255554 Andrade et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Henrique Andrade (Croton-on-Hudson, New York);  Bugra Gedik (White Plains, New York);  Sujay Sunil Parekh (Dobbs Ferry, New York);  Kun-Lung Wu (Yorktown Heights, New York);  Xiaolan Zhang (Champaign, Illinois)
ABSTRACT Techniques for composing an application resource model in a data stream processing system are disclosed. The application resource model may be used to understand what resources will be consumed by an application when executed by the data stream processing system. For example, a method for composing an application resource model for a data stream processing system comprises the following steps. One or more operator-level metrics are obtained from an execution of a data stream processing application in accordance with a first configuration. The application is executed by one or more nodes of the data stream processing system, and the application is comprised of one or more processing elements that are comprised of one or more operators. One or more operator-level resource functions are generated based on the obtained one or more operator-level metrics. A processing element-level resource function is generated based on the one or more generated operator-level resource functions. The processing element-level resource function represents an application resource model usable for predicting one or more characteristics of the application executed in accordance with a second configuration.
FILED Thursday, May 14, 2009
APPL NO 12/466017
ART UNIT 2456 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/231
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255852 Challenger et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) James R. Challenger (Garrison, New York);  Louis R. Degenaro (White Plains, New York);  James R. Giles (Yorktown Heights, New York);  Paul Reed (Brookline, Massachusetts);  Rohit Wagle (Elmsford, New York)
ABSTRACT A distributable and serializable finite state machine and methods for using the distributable and serializable finite state machine are provided wherein finite state machine instance can be location-shifted, time-shifted or location-shift and time-shifted, for example by serializing and deserializing each instance. Each instance can be located-shifted between agents, and a persistent memory storage location is provided to facilitate both location-shifting and time-shifting. Finite state machine instances and the actions that make up each instance can be run in a distributed fashion among a plurality of agents.
FILED Friday, August 14, 2009
APPL NO 12/541830
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/116
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 08252291 Stern et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia);  State Research Center for Applied Microbiology and Biotechnology, Ministry of Health and Social Development, RF, as represented by the Director of the State Research Center for Microbiology and Biotechnology, Ministry of Health and Social Development, RF (Obolensk, Russian Federation)
INVENTOR(S) Norman J Stern (Athens, Georgia);  Edward A Svetoch (Serpukhov District, Russian Federation);  Boris V Eruslanov (Serpukhov District, Russian Federation);  Vladimir V Perelygin (Serpukhov District, Russian Federation);  Vladimir P Levchuk (Serpukhov District, Russian Federation);  Nikolay N Urakov (Olympic vill., Russian Federation);  Larisa I Volodina (Serpukhov District, Russian Federation);  Yuri N. Kovalev (Serpukhov District, Russian Federation);  Tamara Y. Kudryavtseva (Serpukhov District, Russian Federation);  Victor D. Pokhilenko (Serpukhov District, Russian Federation);  Valery N. Borzenkov (Serpukhov District, Russian Federation);  Olga E. Svetoch (Serpukhov District, Russian Federation);  Eugeni V. Mitsevich (Serpukhov District, Russian Federation);  Irina P. Mitsevich (Serpukhov District, Russian Federation)
ABSTRACT Novel bacteriocins produced by novel bacterial strains are used for at least reducing the levels of colonization by at least one target bacteria in animals, especially poultry.
FILED Wednesday, June 01, 2011
APPL NO 13/150678
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/246.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252845 Rimando et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia);  The University of Mississippi (University, Mississippi)
INVENTOR(S) Agnes M. Rimando (Oxford, Mississippi);  Dennis R. Feller (Oxford, Mississippi);  Wallace H. Yokoyama (Berekley, California)
ABSTRACT Resveratrol has been reported to have hypolipidemic properties. We investigated whether resveratrol and its analogs: pterostilbene, piceatannol and resveratrol trimethyl ether, would activate the peroxisome proliferator-activated receptor alpha (PPARα) isoform. This nuclear receptor is proposed to mediate the activity of lipid-lowering drugs such as the fibrates. The four stilbenes and ciprofibrate (positive control) were evaluated for the activation of endogenous PPARα in H4IIEC3 cells transfected with a luciferase gene reporter construct. Pterostilbene demonstrated the highest induction of PPARα; the maximal response to pterostilbene was similar to that obtained with the hypolipidemic drug, ciprofibrate.
FILED Wednesday, February 01, 2012
APPL NO 13/363959
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/720
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP22998 Sakhanonkho
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Hamidou Sakhanonkho (Hattiesburg, Mississippi)
ABSTRACT A new and distinct cultivar of Hedychium plant named ‘Ramata’, characterized by a compact, broad rounded appearance, unique leaf variegation which is uniformly distributed and stable, and mildly fragrant staminate flowers. ‘Ramata’ is the only Hedychium cultivar that combines both dwarfism and leaf variegation.
FILED Thursday, February 17, 2011
APPL NO 12/932111
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/373
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 08252775 Kanter et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California);  U.S. Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Jennifer L. Kanter (Boston, Massachusetts);  William H. Robinson (Palo Alto, California);  Lawrence Steinman (Stanford, California)
ABSTRACT To perform large-scale multiplex analysis of lipid-specific binding, lipid microarrays were developed. Lipids identified as disease associated, or analogs there, can be tolerogenic to patients suffering from autoimmune disease. Lipid array analysis has revealed anti-lipid antibodies in patients with immune disorders, and may contribute to the pathogenesis of disease.
FILED Friday, July 21, 2006
APPL NO 11/491409
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/109
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08252912 Ain et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Kenneth Ain (Lexington, Kentucky);  Wei Li (Lexington, Kentucky)
ABSTRACT The present disclosure relates to a sodium iodide symporter (NIS)-repressor binding site (NRBS) consisting of a DNA molecule spanning from −645 to −605 nucleotides (SEQ ID NO:4) or from −648 to −620 nucleotides (SEQ ID NO:5) upstream from the translation start site of human NIS gene. The disclosure further relates to a method of restoring iodide transport to a human thyroid carcinoma cell, including: the steps of: i) contacting the cell expressing and forming a NIS repressor protein complex capable of binding to the NRBS of the disclosure with a modulator of said complex, and ii) administering to the cell radiolabeled iodide.
FILED Monday, April 21, 2008
APPL NO 12/081790
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 08254491 Dally
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William J. Dally (Stanford, California)
ABSTRACT An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to emphasize transition signal levels relative to repeated signal levels. The preferred equalizer includes an FIR transition filter using a look-up table. Parallel circuits including FIR filters and digital-to-analog converters provide a high speed equalizer with lower speed circuitry. The equalizer is particularly suited to in-cabinet and local area network transmissions where feedback circuitry facilitates adaptive training of the equalizer.
FILED Thursday, August 31, 2006
APPL NO 11/514735
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/295
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255427 Huch
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Alan T. Huch (Richardson, Texas)
ABSTRACT According to one embodiment, a computer-readable medium has computer-executable instructions that, when executed by a computer, are configured to receive an input schema. The input schema specifies how to represent one or more elements in a document. One or more rules are received. The input schema is analyzed for conformance to the one or more rules. If the input schema does not conform to the one or more rules, a modified schema is generated based on the input schema. The modified schema specifies how to represent the one or more elements in the documents in conformance with the one or more rules.
FILED Tuesday, August 18, 2009
APPL NO 12/542831
ART UNIT 2161 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/802
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 08251456 Nolan et al.
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Transportation (USDOT)
APPLICANT(S)
ASSIGNEE(S) Kustom Seating Unlimited (Bellwood, Illinois)
INVENTOR(S) Michael A. Nolan (Greenboro, North Carolina);  William J. Luebke (Aurora, Illinois)
ABSTRACT A locking mechanism comprises an elongate body having first and second rails each having a first end and a second end and a void disposed therebetween. Lock slots are disposed in the first end of each rail and a pad is connected to each of the rails at the second ends to join the first and second rails. A mid bar is rotatably connected to the first and second rails and positioned within the void. An extension is disposed on a second end of the mid bar, wherein the extension provides a visual indication of both a locked state and an unlocked state.
FILED Monday, November 23, 2009
APPL NO 12/623900
ART UNIT 3636 — Static Structures, Supports and Furniture
CURRENT CPC
Chairs and seats
297/463.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253215 Yao
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Wavefront Holdings, LLC (Basking Ridge, New Jersey)
INVENTOR(S) Jie Yao (Princeton, New Jersey)
ABSTRACT A two-terminal mesa phototransistor and a method for making it are disclosed. The photo transistor has a mesa structure having a substantially planar semiconductor surface. In the mesa structure is a first semiconductor region of a first doping type, and a second semiconductor region of a second doping type opposite to that of the first semiconductor region, forming a first semiconductor junction with the first region. In addition, a third semiconductor region of the first doping type forms a second semiconductor junction with the second region. The structure also includes a dielectric layer. The second semiconductor region, first semiconductor junction, and second semiconductor junction each has an intersection with the substantially planar semiconductor surface. The dielectric covers, and is in physical contact with, all of the intersections.
FILED Thursday, January 14, 2010
APPL NO 12/687257
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/461
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 08252763 Tang
FUNDED BY
U.S. State Government
State of Florida
APPLICANT(S)
ASSIGNEE(S) Florida State University Research Foundation (Tallahassee, Florida)
INVENTOR(S) Hengli Tang (Tallahassee, Florida)
ABSTRACT Small interfering RNAs (siRNAs) or small hairpin RNA (shRNAs) and compositions comprising same are provided that specifically target human cyclophilin A (CyPA) to effectively inhibit Hepatitis C(HCV) infection in a cell. Such siRNA and shRNAs may have a length of from about 19 to about 29 contiguous nucleotides corresponding to a specific region of human cyclophilin A (CyPA) cDNA of from about nucleotide 155 to about nucleotide 183 having particular potency against CyPA and HCV. Such siRNA and shRNAs may be formulated as naked compositions or as pharmaceutical compositions. DNA polynucleotides, plasmids, and viral or non-viral vectors are also provided that encode siRNA or shRNA molecules, which may be delivered directly to cells or in combination with known delivery agents, such as lipids, polymers, encapsulated lipid particles, such as liposomes. Methods for treating, managing inhibiting, preventing, etc., HCV infection using such siRNA and shRNAs and compositions comprising same are also provided.
FILED Monday, February 28, 2011
APPL NO 13/036044
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253340 Paton
FUNDED BY
U.S. State Government
State of California
California Energy Commission (CEC)
APPLICANT(S)
ASSIGNEE(S) The Watt Stopper Inc (Santa Clara, California)
INVENTOR(S) John Douglas Paton (Oakland, California)
ABSTRACT A system and device for and a method of programming and controlling light fixtures is disclosed. A system in accordance with the present invention includes a stationary controller unit that is electrically coupled to the light fixtures. The stationary controller unit is configured to be remotely programmed with a portable commissioning device to automatically control the lights fixtures. The stationary controller unit and the portable commissioning device include light sensors, micro-computers and transceivers for measuring light levels, running programs, storing data and transmitting data between the stationary controller unit and the portable commissioning device. In operation, target light levels selected with the portable commissioning device and the controller unit is remotely programmed to automatically maintain the target level.
FILED Friday, September 04, 2009
APPL NO 12/584393
ART UNIT 2821 — Semiconductors/Memory
CURRENT CPC
Electric lamp and discharge devices: Systems
315/155
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 08255235 Aldstadt
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Harry Aldstadt (Woodbridge, Virginia)
ABSTRACT This disclosure describes systems and methods for electronically tracking information. The tracking information may includes arrival information regarding an arrival of the item and processing information regarding processing of the item.
FILED Friday, September 07, 2001
APPL NO 10/488762
ART UNIT 3687 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08255339 Andrew
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Emily Andrew (Martinsburg, West Virginia)
ABSTRACT To temporarily redirect a customer's mail from a current mailing address to a temporary mailing address a request to temporary redirect the customer's mail is received. The request specifies at least one type of mail to redirect, the temporary mailing address, how to redirect the mail, and when to redirect the mail. The customer's mail is directed to the temporary mailing address according to the request.
FILED Tuesday, April 02, 2002
APPL NO 10/473736
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/401
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 08251225 Marino et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by The National Institute of Standards and Technology (Washington, District of Columbia)
INVENTOR(S) John Marino (Silver Spring, Maryland);  Gary Giulian (Gaithersburg, Maryland)
ABSTRACT A method of harvesting carbon nanotubes (CNTs) is provided. According to this method, CNT bundles, comprising CNTs associated with metallic catalysts and having amorphous carbon coatings are agitated in an aqueous liquid containing a dispersant with free-flowing grit particles to disassociate the CNTs from the metallic catalysts, remove the amorphous carbon of the amorphous carbon coatings and shorten the CNTs via shearing.
FILED Monday, September 15, 2008
APPL NO 12/210543
ART UNIT 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Classifying, separating, and assorting solids
29/18
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 08253109 Abeles et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California);  Research Foundation of State University of New York (Albany, New York)
INVENTOR(S) Joseph H. Abeles (East Brunswick, New Jersey);  Serge Luryi (Old Field, New York)
ABSTRACT An article comprising a slab generating scintillation light in response to ionization event and formed with at least two sides. The ionization event is resulted from interaction of high-energy particles within a material of the slab between these sides. A photoreceiver sensitive to the scintillation light is integrated on each side of the slab in an optically-tight fashion. An arrangement is provided for analyzing signals resulted from the ionization event and generated by the photoreceivers. The photoreceivers and the analyzing arrangement are adapted for extracting a position of the ionization event within the slab material relative to the slab sides. A correcting arrangement is provided for correcting the signals and to provide attenuation of the scintillation light.
FILED Tuesday, November 15, 2011
APPL NO 13/296516
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/366
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 08251456 Nolan et al.
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Transportation (USDOT)
APPLICANT(S)
ASSIGNEE(S) Kustom Seating Unlimited (Bellwood, Illinois)
INVENTOR(S) Michael A. Nolan (Greenboro, North Carolina);  William J. Luebke (Aurora, Illinois)
ABSTRACT A locking mechanism comprises an elongate body having first and second rails each having a first end and a second end and a void disposed therebetween. Lock slots are disposed in the first end of each rail and a pad is connected to each of the rails at the second ends to join the first and second rails. A mid bar is rotatably connected to the first and second rails and positioned within the void. An extension is disposed on a second end of the mid bar, wherein the extension provides a visual indication of both a locked state and an unlocked state.
FILED Monday, November 23, 2009
APPL NO 12/623900
ART UNIT 3636 — Static Structures, Supports and Furniture
CURRENT CPC
Chairs and seats
297/463.200
VIEW PATENT @ USPTO:  Full Text   PDF 

National Reconnaissance Office (NRO) 

US 08253171 Derderian et al.
FUNDED BY
National Reconnaissance Office (NRO)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Garo J. Derderian (Manassas, Virginia);  Michael J. O'Connor (Manassas Park, Virginia);  Adrian N. Robinson (Haymarket, Virginia);  Jonathan W. Ward (Fairfax, Virginia)
ABSTRACT A two terminal switching device includes a first conductive terminal, a second conductive terminal in spaced relation to the first terminal, the first terminal encompassed by the second terminal. The device also includes an electrically insulating spacer that encompasses the first terminal and provides the spaced relation between the second terminal and the first terminal. It also includes a nanotube article comprising at least one carbon nanotube, the nanotube article being arranged to overlap at least a portion of each of the first and second terminals. The device also includes a stimulus circuit in electrical communication with at least one of the first and second terminals that is capable of applying a first electrical stimulus to at least one of the first and second terminals to change the resistance of the device between the first and second terminals from a relatively low resistance to a relatively high resistance.
FILED Monday, August 16, 2010
APPL NO 12/857494
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/204
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08252592 Sadelain et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Memorial Sloan-Kettering Cancer Center (New York, New York)
INVENTOR(S) Michel Sadelain (New York, New York);  Matthias Stephan (Boston, Massachusetts)
ABSTRACT The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen-recognizing receptor and a co-stimulatory ligand and methods of use therefore for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired.
FILED Monday, March 31, 2008
APPL NO 12/593751
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/455
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08253443 Robinett
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S) Warren Robinett (Chapel Hill, North Carolina)
ABSTRACT An interconnection architecture for multilayer circuits includes metal-insulator transition channels interposed between address leads and each bar in the multilayer circuit. An extrinsic variable transducer selectively transitions the metal-insulator channels between insulating and conducting states to selectively connect and disconnect the bars and the address leads. A method for accessing a programmable crosspoint device within a multilayer crossbar circuit is also provided.
FILED Tuesday, October 26, 2010
APPL NO 12/912647
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Electronic digital logic circuitry
326/103
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, August 28, 2012.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2012/fedinvent-patents-20120828.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital