FedInvent™ Patents

Patent Details for Tuesday, October 23, 2012 

This page was updated on Monday, March 27, 2023 at 03:25 AM GMT

Department of Defense (DOD) 

US 08291567 Keenan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Timothy James Keenan (San Diego, California);  Joshua Bianchi (San Diego, California)
ABSTRACT In one embodiment, the present invention provides a method for forming battery tray for holding cylindrical cell batteries. The method includes forming a battery try including a base support having a generally flat bottom surface and multiple adjacent cylindrical cavities are formed within the base support, using a circle packing algorithm to form the cylindrical cavities. The adjacent cavities each have at least some interstitial cylindrical riser wall structures formed with a predetermined height to hold the cylindrical cell batteries. In another embodiment, the present invention allows for packing maximum energy density per layer. This allows lifetime and power output of a battery powered device to be optimized and/or increased.
FILED Wednesday, August 25, 2010
APPL NO 12/868125
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/407.90
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291589 Davis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Ephraim C. Davis (North Richland Hills, Texas);  Christopher J. Bischof (Southlake, Texas)
ABSTRACT A method for use in repairing gas turbine engine components includes applying a stress to a first gas turbine engine component to cause surface cracking on the first gas turbine engine component and establishing a location of an elevated stress region of a second gas turbine engine component based upon the location of the surface cracking on the first gas turbine engine component.
FILED Wednesday, August 08, 2007
APPL NO 11/835452
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/889.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291706 Tanner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Keith M. Tanner (Colchester, Connecticut);  Philip J. Kirsopp (Lebanon, Connecticut)
ABSTRACT A bearing plate assembly for a turbine engine fuel injector includes a bearing plate 30, with an opening 80 bordered by a race 82. A swivel ball 90 nests inside the race and is rotatable relative thereto. A lock, which may be a tip bushing 108 resists disengagement of the swivel ball from the race. A fuel injector nozzle 38 extends through an opening 98 in the swivel ball. During engine operation, the ball can swivel inside the race to accommodate rotational movement of the nozzle about lateral and radial axes.
FILED Thursday, June 11, 2009
APPL NO 12/482516
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/740
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291712 Ponziani
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Robert Louis Ponziani (West Chester, Ohio)
ABSTRACT A method for determining sensor locations in a gas turbine engine is provided. The said method includes providing a turbine rear frame including a radially inner surface, a radially outer surface and a plurality of circumferentially-spaced struts extending between the inner and outer surfaces, wherein a strut sector is defined between each pair of circumferentially-adjacent struts, providing a plurality of fuel nozzles that are each aligned with a strut sector, selecting one of the plurality of fuel nozzles as a primary index nozzle and positioning each of a plurality of sensors relative to one of the plurality of nozzles using a corresponding positioning angle such that each of the plurality of sensors coincides with a gas flow temperature distribution profile between each pair of circumferentially-spaced nozzles.
FILED Wednesday, June 16, 2010
APPL NO 12/816572
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/772
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291768 Spiegel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) Beth Israel Deaconess Medical Center (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Joan E. Spiegel (Boston, Massachusetts);  Alexander H. Slocum (Cambridge, Massachusetts);  Adrienne Watral (Lynnwood, Washington);  Samuel Duffley (Billerica, Massachusetts)
ABSTRACT A syringe having an internal pressure gauge comprises a syringe barrel; a piston within the barrel; a spring coupled to the piston at a first position of the spring, the spring having a second portion that is movable in response to fluid pressure within a syringe cavity; and a pressure gauge having an indicator correlated to a plurality of positions of the second portion of the spring to indicate a pressure of a fluid. The spring can be a bellows. The fluid chamber can be in fluid communication with a cuff of an inflatable medical device, such as an endotracheal tube, such that the measured pressure comprises the fluid pressure within the cuff.
FILED Friday, January 15, 2010
APPL NO 12/688599
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291895 Sudarshan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Tangali Sudarshan (Columbia, South Carolina);  Igor Agafonov (Columbia, South Carolina);  Robert Kennedy (Columbia, South Carolina)
ABSTRACT Methods, wires, and apparatus for use in cutting (e.g., slicing) hard, brittle materials is provided. The wire can be a super-abrasive wire that includes a wire core and super-abrasive particles bonded to the wire core via a metal bonding layer. This wire, or another type of wire, can be used to slice workpieces useful for producing wafers. The workpieces can be aligned within a holder to produce wafers using the device and methods presently provided. The holder rotates about its central axis, which translates to workpieces moving in orbit around this axis. A single abrasive wire, or multiple turns of wire stretched tightly between wire guides, is then contacted with the rotating holder to slice the workpieces.
FILED Friday, September 05, 2008
APPL NO 12/205046
ART UNIT 3727 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Stone working
125/21
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291963 Trinks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Steven W. Trinks (Wallingford, Connecticut);  Tracy A. Proctor-Hinckley (Manchester, Connecticut);  Steven J. Bullied (Pomfret Center, Connecticut)
ABSTRACT A hybrid core assembly for a casting process includes a ceramic core portion and a refractory metal core portion that interfaces with a ceramic core trough of the ceramic core portion. The refractory metal core portion includes a finger having a bent portion that establishes a refractory metal core trough aligned with the ceramic core trough.
FILED Wednesday, August 03, 2011
APPL NO 13/196989
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal founding
164/369
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291990 Mohr
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John A. Mohr (Camarillo, California)
ABSTRACT A fire fighting system for fighting forest and brush fires under dry, hot and windy conditions which includes a jet engine for generating a high speed air stream, a water source for supplying water to a cooling system which lowers the water temperature to between forty and fifty degrees Fahrenheit, a nozzle for injecting cold water into the air steam and a filter which provides very fine particles of cold water within the stream. The stream of cold water is directed to a forest or brush fire dropping the temperature of the fire which eventually extinguishes the fire.
FILED Monday, August 31, 2009
APPL NO 12/550684
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Fire extinguishers
169/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292216 Rumberger, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) William Elmer Rumberger, Jr. (Newtown Square, Pennsylvania)
ABSTRACT A method and apparatus may be present for moving a wing. A plurality of lifting assemblies may be attached to a first plurality of channels in a ring associated with the wing of an aircraft. A plurality of base assemblies may be attached to a plurality of fittings with a second plurality of channels associated with a fuselage of the aircraft. The plurality of lifting assemblies may be moved away from the plurality of base assemblies using a plurality of biasing systems such that the ring may move away from the fuselage.
FILED Wednesday, December 16, 2009
APPL NO 12/639505
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/39
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292231 Sadeck
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) James E. Sadeck (East Freetown, Massachusetts)
ABSTRACT An apparatus for releasing a parachute from its payload upon ground impact by the payload. The apparatus has a pair of sections releasably secured to each other. Each section has an intermediate portion having a longitudinally extending axis and a spur receiving opening that extends through the intermediate portion and is transverse to the longitudinally extending axis, a first end portion attached to the intermediate portion and comprising a spur that extends in a generally lateral direction with respect to the longitudinally extending axis, and a second end portion attached to the intermediate portion such that the intermediate portion is between the first and second end portions. Each section is configured so that a lanyard can be connected to the section wherein in order to use the apparatus, a lanyard is attached to and between one section and a parachute, and another lanyard is attached to and between the other section and a payload.
FILED Monday, August 22, 2011
APPL NO 13/214290
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/151.B00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292510 Glahn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Jorn A. Glahn (Manchester, Connecticut);  Denman H. James (Windsor, Connecticut);  William G. Sheridan (Southington, Connecticut)
ABSTRACT A system for removing oil from a bearing compartment has a port connected to an end wall of the compartment through which the oil exits the compartment, a scavenge scoop connected to the port for collecting the oil, and a separation device connected to the scavenge scoop for creating an oil collection region.
FILED Thursday, September 28, 2006
APPL NO 11/540111
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Bearings
384/462
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292581 Poon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Kin C. Poon (Tempe, Arizona);  Malak F. Malak (Tempe, Arizona);  Rajiv Rana (Tempe, Arizona);  Ardeshir Riahi (Scottsdale, Arizona);  David H. Chou (Phoenix, Arizona)
ABSTRACT An air-cooled turbine blade and methods of manufacturing the blade are provided. The blade includes a suction side flow circuit formed within its interior and defined at least by an interior surface of a convex suction side wall, a pressure side flow circuit formed within the blade interior and defined at least by an interior surface of a concave pressure side wall, and a center flow circuit including a first section and a second section, the first section disposed between the suction side flow circuit and the pressure side flow circuit, and the second section in flow communication with the first section and a plurality of openings of a leading edge wall and defined at least partially by an interior surface of the leading edge wall.
FILED Wednesday, January 09, 2008
APPL NO 11/971459
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/97.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292587 Poon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Kin Poon (Tempe, Arizona);  Rajiv Rana (Phoenix, Arizona);  Bob Mitlin (Scottsdale, Arizona);  Ardeshir Riahi (Scottsdale, Arizona);  David Chou (Phoenix, Arizona);  Steve Halfmann (Chandler, Arizona);  Frank Mignano (Phoenix, Arizona)
ABSTRACT A turbine blade assembly includes an airfoil, a platform, and a first cover plate. A center flow path extends through the platform in communication with an internal cooling circuit of the airfoil, which extends from a first side of the platform. A second side of the platform is located opposite the platform from the first side. An edge of the platform extends between the first and second sides and, a first passage is formed between the first and second sides and includes a first inlet and a first outlet. The first passage extends from the center flow path toward the platform edge, and a first groove is formed on the second side of the platform and extends from the first outlet of the first passage toward the edge of the platform. The first cover plate is disposed over the second side of the platform covering the first groove.
FILED Thursday, December 18, 2008
APPL NO 12/338746
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Fluid reaction surfaces
416/193.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292592 Welch et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) David A. Welch (Quaker Hill, Connecticut);  Phillip Alexander (Colchester, Connecticut)
ABSTRACT A device includes a resilient member having a first end for blocking an access hole and a second end for attachment to a support surface, an opening extending through the resilient member and located between the first and second ends, and a bolt connection location positioned at the second end of the resilient member. The first end of the resilient member blocks the access hole and can be deflected to provide tool access to the bolt connection location through the first opening.
FILED Wednesday, April 02, 2008
APPL NO 12/080383
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/245.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292651 Lakeman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) BAE Systems Land and Armaments, L.P. (Santa Clara, California)
INVENTOR(S) Ryan C. Lakeman (Plymouth, Minnesota);  Randall J. Appleton (West St. Paul, Minnesota);  Dennis W. Borgwarth (Andover, Minnesota)
ABSTRACT An output connector for a high voltage, high current power unit, including a plug assembly including a dielectric plug body having two conductive biplates arranged generally parallel to each other. The two conductive biplates abut a dielectric biplate backer and the two conductive biplates are separated by the dielectric biplate backer. A header assembly includes a dielectric header body presenting two substantially parallel, inwardly facing, vertical support walls on opposing sides of the receptacle recess. A bus bar assembly includes two contactors coupled to a flexible bus bar and abutting the vertical support walls. The two contactors are arranged such that a space exists between the contactors. A ring assembly is couplable to the plug assembly and structured to force the plug assembly axially inward to the header assembly whereby the biplates and the biplate backer are forced between the contactors.
FILED Thursday, June 09, 2011
APPL NO 13/156398
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electrical connectors
439/345
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292680 Herr et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael D. Herr (Ridgecrest, California);  Jack L. Ingle (Ridgecrest, California)
ABSTRACT An external brass seal for a floatation device includes a body having an upper portion, a lower portion, at least one aperture, and a seal. The aperture extends through the body and is adapted to transfer fluid into the upper portion and out of the lower portion.
FILED Monday, July 26, 2010
APPL NO 12/843257
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Buoys, rafts, and aquatic devices
441/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292991 Friday et al.
FUNDED BY
Department of Defense (DOD)
United States Special Operations Command (SOCOM)
APPLICANT(S)
ASSIGNEE(S) Avon Protection Systems, Inc. (Cadillac, Michigan)
INVENTOR(S) David K. Friday (Cockeysville, Maryland);  John Schlaechter (Columbus, Ohio);  Wayne E. Ballantyne (Columbus, Ohio);  Robert J. Puhala (Frederick, Maryland);  David W. Pike (Salisbury, United Kingdom)
ABSTRACT A filter for a gas mask has a concave outlet wall and a convex inlet wall with a particulate filter bed that has a uniform depth and conforms substantially to the shape of the inlet and outlet wall. The side wall can have an elliptical, circular or convex shape to conform to the curvature of the wearer's face, or a planar shape. The filter an be a double particulate filter element and a double adsorption filter element configured for axial airflow therethrough with a bifurcated flow pattern. The adsorption filter element comprises a granulated charcoal, a composite material having carbon particles combined with binder particles, or an immobilized bed of charcoal granules and EVA-coated fibers.
FILED Wednesday, October 31, 2007
APPL NO 11/930645
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Gas separation: Apparatus
096/134
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293040 Gangopadhyay et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Shubhra Gangopadhyay (Columbia, Missouri);  Daniel Tappmeyer (Warrenton, Missouri);  Andrey Bezmelnytsin (Columbia, Missouri);  Rajagopalan Thiruvengadathan (Columbia, Missouri);  Rajesh Shende (Rapid City, South Dakota);  Bhusban Mehendale (Land-O-Lakes, Florida);  Steven Apperson (Columbia, Missouri);  Syed Barizuddin (Columbia, Missouri);  Keshab Gangopadhyay (Columbia, Missouri)
ABSTRACT The invention provides homogeneous mesoporous metal oxide nanoenergetic composites. A composite of the invention has a regular and uniform nanostructure of metal oxide, which is structured by a surfactant. Metal fuel nanoparticles are homogenously distributed through the regular and uniform nanostructure. The invention further provides methods for making homogeneous metal oxide nanoenergetic composites. A method of the invention forms a metal oxide nanostructure via a sol-gel process with surfactant templating. Metal nanoparticles into the metal oxide nanostructure via wet impregnation.
FILED Tuesday, December 11, 2007
APPL NO 12/001306
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosive and thermic compositions or charges
149/37
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293064 Chang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Cepheid (Sunnyvale, California)
INVENTOR(S) Ronald Chang (Redwood City, California);  Douglas B. Dority (Mill Valley, California)
ABSTRACT A reaction vessel having a reaction chamber for holding a sample is fabricated by producing a housing having a rigid frame defining the minor walls of the chamber. The housing also defines a port for introducing fluid into the chamber. At least one sheet or film is attached to the rigid frame to form at least one major wall of the chamber. In preferred embodiments, two sheets or films are attached to opposite sides of the rigid frame to form two opposing major walls of the chamber, the major walls being connected to each other by the minor walls.
FILED Monday, March 03, 2003
APPL NO 10/379004
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/308.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293083 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Henry S White (Salt Lake City, Utah);  Bo Zhang (Salt Lake City, Utah);  Ryan J White (Salt Lake City, Utah);  Eric N Ervin (Salt Lake City, Utah);  Gangli Wang (Salt Lake City, Utah)
ABSTRACT Provided are fabrication, characterization and application of a nanodisk electrode, a nanopore electrode and a nanopore membrane. These three nanostructures share common fabrication steps. In one embodiment, the fabrication of a disk electrode involves sealing a sharpened internal signal transduction element (“ISTE”) into a substrate, followed by polishing of the substrate until a nanometer-sized disk of the ISTE is exposed. The fabrication of a nanopore electrode is accomplished by etching the nanodisk electrode to create a pore in the substrate, with the remaining ISTE comprising the pore base. Complete removal of the ISTE yields a nanopore membrane, in which a conical shaped pore is embedded in a thin membrane of the substrate.
FILED Thursday, November 18, 2010
APPL NO 12/949469
ART UNIT 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/420
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293107 Lobovsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Alex Lobovsky (Westfield, New Jersey);  Wesley P. Hoffman (Palmdale, California);  Phillip G. Wapner (Palmdale, California)
ABSTRACT New fluid separation devices and absorption materials are disclosed. Hollow fibers with an axial capillary slit act as very high efficiency absorption materials, as well as high-surface-area fluid separation devices. The hollow fibers with an axial capillary slit are constructed to preferentially absorb or repel different fluids and arranged to maximize that action over a plurality of fibers to separate different fluids. These separation devices can also function as injection devices and very effective micro-reactors.
FILED Monday, January 11, 2010
APPL NO 12/684993
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/321.880
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293245 Smith et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland)
INVENTOR(S) Michael Smith (Silver Spring, Maryland);  Angela Melton-Celsa (Sterling, Virginia);  Alison O'Brien (Bethesda, Maryland)
ABSTRACT The invention is based on the discovery of the epitope in the Stx1 protein for the 13C4 antibody. The invention features non-full length Stx1 polypeptides that include the epitope for the 13C4 monoclonal antibody epitope. The invention also features methods of producing anti-Stx1 antibodies specific for the 13C4 epitope of the Stx1 protein. Additionally, the invention features methods for treating a subject having, or at risk of developing, a Shiga toxin associated disease (e.g., hemolytic uremia syndrome and diseases associated with E. coli and S. dysenteriae infection) with a polypeptide that includes the 13C4 epitope or with an anti-Stx1 antibody developed using the methods of the invention. Furthermore, the invention features the detection of Stx1 in a sample using the antibodies developed using the methods of the invention.
FILED Friday, April 20, 2007
APPL NO 11/788546
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/192.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293362 Huston et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Alan L Huston (Aldie, Virginia);  Brian L Justus (Springfield, Virginia)
ABSTRACT A closed-cell foam glass structure comprising a multitude of micron-sized voids enclosed by interconnected glass membranes with sub-micron thickness wherein the voids are from about 30% to about 70% of the volume.
FILED Thursday, July 29, 2010
APPL NO 12/846200
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Stock material or miscellaneous articles
428/312.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293531 Burg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)
ASSIGNEE(S) Clemson University Research Foundation (Clemson, South Carolina)
INVENTOR(S) Karen J. L. Burg (Clemson, South Carolina);  Chih-Chao Yang (Seneca, South Carolina)
ABSTRACT Disclosed are three-dimensional (3D) systems as may be utilized for ex vivo tissue or cell growth and development. A system generally includes a base material and at least one wicking fiber embedded therein through which a liquid can be spontaneously drawn by capillary action. Wicking fibers can define a plurality of colinear channels along the exterior surface of the axial length of the fiber. Wicking fibers can be present in disclosed systems as individual fibers or in bundles. Disclosed systems can be useful in various scientific studies, including, but not limited to, drug discovery, vaccine development, cell biology studies, and biomaterial development.
FILED Friday, August 29, 2008
APPL NO 12/201297
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/398
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293685 Daugherty et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Patrick S. Daugherty (Santa Barbara, California);  Jeffrey Rice (Grayson, Georgia)
ABSTRACT Methods of making and using bacterial display polypeptide libraries using circularly permuted OmpX (CPX) variants are disclosed. The invention further relates to methods for enhancing the display of proteins and peptides at the surface of bacteria by optimizing linkers and incorporating mutations at positions 165 and 166 of CPX.
FILED Thursday, July 24, 2008
APPL NO 12/220448
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Combinatorial chemistry technology: Method, library, apparatus
56/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293725 Berkman
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Cancer Targeted Technology LLC (San Francisco, California)
INVENTOR(S) Cliff Berkman (San Francisco, California)
ABSTRACT Compounds of the formula, A-L-B, wherein A is glutamate or a glutamate analog; L is a phosphoramidate or a phosphoramidate analog; and B is serine or a serine analog are described which are potent inhibitors of prostate-specific membrane antigen (PMSA). Such compounds are useful in treatment of prostate cancer; and when chemically attached to a fluorescent dye, can efficiently and selectively label prostate cancer cells for fluorescent imaging.
FILED Friday, January 22, 2010
APPL NO 12/691957
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/114
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293764 Lee et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Wen-Hwa Lee (Newport Coast, California);  Phang-Lang Chen (Irvine, California);  Jiewen Zhu (Irvine, California)
ABSTRACT Contemplated compounds disrupt interaction between BRCA2 and RAD51, likely by binding to RAD51. Based on the crucial role of the BRCA2-RAD51 complex formation in DNA repair and the role of RAD51 in the control of entry into S-phase from G1, numerous compositions and methods are presented. Among other advantageous uses, contemplated compounds may be employed as protective agents for non-neoplastic cells in chemotherapy before exposure of the cells to a chemotherapeutic drug, and/or as DNA-damage sensitizer for neoplastic cells.
FILED Wednesday, October 19, 2005
APPL NO 11/577445
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/311
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293818 Costantino et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) EnerG2 Technologies, Inc. (Seattle, Washington)
INVENTOR(S) Henry R. Costantino (Woodinville, Washington);  Aaron Feaver (Seattle, Washington);  William D. Scott (Seattle, Washington)
ABSTRACT The present application is generally directed to activated carbon materials and methods for making the same. The disclosed methods comprise rapidly freezing synthetically prepared polymer gel particles. The methods further comprise drying, pyrolyzing, and activating steps to obtain an activated carbon material of high porosity. The disclosed methods represent viable manufacturing processes for the preparation of activated carbon materials.
FILED Thursday, April 08, 2010
APPL NO 12/756668
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
523/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294007 Shenoy et al.
FUNDED BY
Department of Commerce (DOC)
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia);  The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia)
INVENTOR(S) Devanand K. Shenoy (McLean, Virginia);  Alok Singh (Springfield, Virginia);  William R. Barger (Cobb Island, Maryland);  John J. Kasianowicz (Darnestown, Maryland)
ABSTRACT A membrane is disclosed made from a compound having a hydrophilic head group, an aliphatic tail group, and a polymerizable functional group. The membrane spans an aperture and may be polymerized. The membrane may be useful for DNA sequencing when the membrane includes an ion channel.
FILED Monday, February 28, 2005
APPL NO 11/070398
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Nanotechnology
977/713
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294032 Heisen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Peter Timothy Heisen (Kent, Washington);  Harold Peter Soares, Jr. (Tacoma, Washington)
ABSTRACT A method and apparatus for aligning components on a module are disclosed. A flexible circuit may be attached to a module in which a tooling apparatus is attached to the module. A plurality of circuit pads on a functional section of the flexible circuit is aligned by a first alignment structure located on a sacrificial portion of the flexible circuit to a second alignment structure on the tooling apparatus. The flexible circuit is attached to the module while the flexible circuit is in an aligned position.
FILED Wednesday, February 10, 2010
APPL NO 12/703477
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Conductors and insulators
174/254
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US 08294060 Mohanty et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Pravansu S. Mohanty (Canton, Michigan);  Nicholas Anton Moroz (Northville, Michigan)
ABSTRACT A method and apparatus for forming layers on a target. The apparatus and method employ a direct current plasma apparatus to form at least one layer using a plasma jet containing precursors. In some embodiments, the direct current plasma apparatus utilizes axial injection of the precursors through the cathode (in an upstream and/or downstream configuration) and/or downstream of the anode. In some embodiments, the direct current plasma apparatus can comprise a laser source for remelting the layer using a laser beam to achieve in-situ densification thereof.
FILED Monday, May 03, 2010
APPL NO 12/772342
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Electric heating
219/121.370
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294078 Mazumder et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Sudip K. Mazumder (Chicago, Illinois);  Tirthajyoti Sarkar (Chicago, Illinois)
ABSTRACT A multi-stage optically-triggered power system. At least one triggering stage is responsive to at least one optical trigger to directly create photogeneration of carriers in the at least one triggering stage and thus generate at least one output signal. At least one main power device stage coupled to the at least one triggering stage is responsive to the at least one generated output signal to activate the at least one main power device stage. The at least one triggering stage and the at least one main power device stage may be monolithically integrated.
FILED Wednesday, June 11, 2008
APPL NO 12/157694
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/214.SW0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294135 Lebedev et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Nikolai Lebedev (Springfield, Virginia);  Scott A Trammell (Springfield, Virginia);  Stanislav Tsoi (Alexandria, Virginia);  Mark E Twigg (Falls Church, Virginia);  Joel M Schnur (Burke, Virginia)
ABSTRACT A high power density photo-electronic and photo-voltaic material comprising a bio-inorganic nanophotoelectronic material with a photosynthetic reaction center protein encapsulated inside a multi-wall carbon nanotube or nanotube array. The array can be on an electrode. The photosynthetic reaction center protein can be immobilized on the electrode surface and the protein molecules can have the same orientation. A method of making a high power density photo-electronic and photo-voltaic material comprising the steps of immobilizing a bio-inorganic nanophotoelectronic material with a photosynthetic reaction center protein inside a carbon nanotube, wherein the immobilizing is by passive diffusion, wherein the immobilizing can include using an organic linker.
FILED Monday, May 10, 2010
APPL NO 12/776796
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294137 Jain et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Faquir Chand Jain (Storrs, Connecticut);  Evan Heller (Glastonbury, Connecticut)
ABSTRACT A field-effect transistor is provided and includes source, gate and drain regions, where the gate region controls charge carrier location in the transport channel, the transport channel includes a asymmetric coupled quantum well layer, the asymmetric quantum well layer includes at least two quantum wells separated by a barrier layer having a greater energy gap than the wells, the transport channel is connected to the source region at one end, and the drain regions at the other, the drain regions include at least two contacts electrically isolated from each other, the contacts are connected to at least one quantum well. The drain may include two regions that are configured to form the asymmetric coupled well transport channel. In an embodiment, two sources and two drains are also envisioned.
FILED Monday, January 04, 2010
APPL NO 12/655609
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/24
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294138 Farinelli et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Matthew J. Farinelli (Bronx, New York);  George A. Keefe (Cortlandt Manor, New York);  Shwetank Kumar (White Plains, New York);  Matthias Steffen (Cortlandt Manor, New York)
ABSTRACT A method for determining whether a quantum system comprising a superconducting qubit is occupying a first basis state or a second basis state once a measurement is performed is provided. The method, comprising: applying a signal having a frequency through a transmission line coupled to the superconducting qubit characterized by two distinct, separate, and stable states of differing resonance frequencies each corresponding to the occupation of the first or second basis state prior to measurement; and measuring at least one of an output power or phase at an output port of the transmission line, wherein the measured output power or phase is indicative of whether the superconducting qubit is occupying the first basis state or the second basis state.
FILED Monday, February 14, 2011
APPL NO 13/026339
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/31
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294141 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Zhong L. Wang (Marietta, Georgia);  Changshi Lao (Atlanta, Georgia);  Jun Zhou (Atlanta, Georgia)
ABSTRACT An ultraviolet light sensor includes an elongated metal oxide nanostructure, a layer of an ultraviolet light-absorbing polymer, a current source and a current detector. The elongated metal oxide nanostructure has a first end and an opposite second end. The layer of an ultraviolet light-absorbing polymer is disposed about at least a portion of the metal oxide nanostructure. The current source is configured to provide electrons to the first end of the metal oxide nanostructure. The current detector is configured to detect an amount of current flowing through the metal oxide nanostructure. The amount of current flowing through the metal oxide nanostructure corresponds to an amount of ultraviolet light impinging on the metal oxide nanostructure.
FILED Tuesday, July 07, 2009
APPL NO 12/498605
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294507 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Qingchun Zhang (Cary, North Carolina);  James Theodore Richmond (Hillsborough, North Carolina);  Robert J. Callanan (Raleigh, North Carolina)
ABSTRACT An electronic device includes a wide bandgap thyristor having an anode, a cathode, and a gate terminal, and a wide bandgap bipolar transistor having a base, a collector, and an emitter terminal. The emitter terminal of the bipolar transistor is directly coupled to the anode terminal of the thyristor such that the bipolar transistor and the thyristor are connected in series. The bipolar transistor and the thyristor define a wide bandgap bipolar power switching device that is configured to switch between a nonconducting state and a conducting state that allows current flow between a first main terminal corresponding to the collector terminal of the bipolar transistor and a second main terminal corresponding to the cathode terminal of the thyristor responsive to application of a first control signal to the base terminal of the bipolar transistor and responsive to application of a second control signal to the gate terminal of the thyristor. Related control circuits are also discussed.
FILED Friday, May 08, 2009
APPL NO 12/437929
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Miscellaneous active electrical nonlinear devices, circuits, and systems
327/440
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294560 Hilger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) James E Hilger (Reston, Virginia);  John D Hodapp (Springfield, Virginia);  Sean M Jellish (Fairfax, Virginia);  Christopher H Marshall (Alexandria, Virginia);  John K Ramsey, Jr. (Annandale, Virginia);  Philip Perconti (Alexandria, Virginia)
ABSTRACT A system of imaging and non-imaging sensors are used in combination with a graphical user interface (GUI) system on a vehicle to detect items of interest. In particular, a GUI has been developed that seamlessly integrates high magnification, Narrow Field of View (NFOV) imaging sensors and Wide Field of View (WFOV) imaging sensors. The GUI is capable of displaying both WFOV and NFOV images, gimbal controls, and allow NFOV sensor to be pointed to any location within the wide field of view efficiently by a single touch of a touch screen display. The overall goal is to allow an operator to select which imagery from multiple WFOV sensors to display in order to prescreen regions of interest that require further investigation using sensors with more magnification.
FILED Monday, July 20, 2009
APPL NO 12/505622
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/435
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294603 Sze et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Vivienne Sze (Toronto, Canada);  Anantha P. Chandrakasan (Belmont, Massachusetts)
ABSTRACT A system and method for providing high throughput entropy coding contains the steps of: dividing syntax elements of video into one or more group of syntax elements; placing each group into a separate partition, resulting in more than one partition; and processing more than one of the more than one partition in parallel using entropy coding.
FILED Wednesday, June 30, 2010
APPL NO 12/827872
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/107
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294712 Nelson
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) James M. Nelson (Sumner, Washington)
ABSTRACT Techniques for facilitating detection of an object in a point cloud of three-dimensional imaging data representing an area of study where the object potentially is obscured by intervening obstacles are provided. The imaging data is processed to identify elements in the point cloud having substantially common attributes signifying that the identified elements correspond to a feature in the area of study. An isosurface is generated associating the elements having substantially common attributes. A reversed orientation visualization model for a region of interest is generated. The reversed orientation visual model areas of total occlusion that potentially signify presence of the object.
FILED Tuesday, July 10, 2007
APPL NO 11/775430
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/421
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294775 McCloskey
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Scott McCloskey (Minneapolis, Minnesota)
ABSTRACT A fluttering illumination system and method for encoding the appearance of a moving subject includes an image capturing device, a lens, a shutter, an illumination source, and a device to control illumination triggering and power. The image capturing device may be configured in a bulb shutter mode to integrate light patterns from the object upon the sensor via the shutter until a shutter release is open. The control device may be invoked to trigger several illuminations of varying power in a predetermined sequence by rapidly turning the illumination source on and off when the shutter release is open. The shutter release may then be closed following the firing of a last illumination in order to invertibly encode the appearance of the moving subject in a single image. Data indicative of a motion blur associated with the image may be estimated and the image processed to recover a sharp image without noise and ringing artifacts.
FILED Thursday, October 22, 2009
APPL NO 12/604012
ART UNIT 2622 — Selective Visual Display Systems
CURRENT CPC
Television
348/208.990
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294982 Her
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of North Carolina at Charlotte (Charlotte, North Carolina)
INVENTOR(S) Tsinghua Her (Charlotte, North Carolina)
ABSTRACT A fiber, such as a photonic bandgap fiber, is provided, the fiber including a core and a cladding. The core can extend longitudinally and can have a gain medium configured to provide laser amplification to laser radiation propagating along the core. For example, the gain medium may include a dopant configured to provide amplification, when activated by one or more modes of excitation radiation, of laser radiation propagating along said core. The cladding can be radially exterior to the core, and can be configured to provide a low-loss propagation the one or more modes of excitation radiation and a lossy propagation of all modes of laser radiation along the core, the lossy propagation higher than the low-loss propagation, in particular when the one or more modes of excitation radiation is substantially absent from the core. Associated methods and apparatuses are also provided.
FILED Thursday, July 08, 2010
APPL NO 12/832583
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Optical: Systems and elements
359/341.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295046 St. Rock et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Windsor Locks, Connecticut)
INVENTOR(S) Brian St. Rock (Andover, Connecticut);  Scott F. Kaslusky (West Hartford, Connecticut)
ABSTRACT A heat sink includes a blower located in the heat sink and a plurality of fins extending from a periphery of the blower toward a perimeter of the heat sink. The plurality of fins define a plurality of channels each having a channel inlet located at the blower and a channel exit located at the perimeter of the heat sink. The plurality of channels vary in length around the perimeter of the heat sink A velocity of an air flow from the blower at each channel inlet is substantially equal for each channel of the plurality of channels, and a total pressure drop from the channel inlet to the channel exit is substantially equal for each channel of the plurality of channels.
FILED Monday, July 19, 2010
APPL NO 12/838536
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/697
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295309 Jeng
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Isaac M. Jeng (Yorba Linda, California)
ABSTRACT A method for time weighted combining of a plurality of binary phase shift key (BPSK) code sequences that is implemented by providing first, second and third sequences of chips of a BPSK code having a first, second and third code powers, respectively. A majority vote (MV) sequence of chips from the first, second and third sequences of chips is determined and a time multiplexed composite BPSK composite code sequence is formed by selecting a specific number of samples from each of the MV sequence of chips, and the two sequences of chips of the first, second and third sequences of chips that have the highest code powers, to form samples in a unit duration.
FILED Friday, March 14, 2008
APPL NO 12/049007
ART UNIT 2463 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/498
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295326 Reid
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Space and Missile Defense Command (SMDC)
United States Special Operations Command (SOCOM)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Ceri Reid (Largo, Florida)
ABSTRACT Provided is a system and method of digitally encoding and decoding digital data during the transmission process using a combination of Direct Sequence Spread Spectrum (DSSS) and turbo coding. A DSSS de-spreading process is used in place of the outer decoder functional block of a turbo decoder, which removes the need for a dedicated outer ECC code. Removal of the dedicated outer ECC code allows for an increase in the actual data rate transmitted through the channel (compared with a system which uses a discrete DSSS stage after Turbo coding or some other ECC code) because the number of bits to be transmitted for a given data rate has been reduced.
FILED Friday, June 12, 2009
APPL NO 12/483471
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/146
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295409 Su
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Wei Su (Bel Air, Maryland)
ABSTRACT A multi-sensor signal fusion apparatus is provided for automatic modulation classification of weak unknown signals in non-cooperative communication environment with a more accurate description of the signal. The multi-sensor non-cooperative demodulation device combines a group of sensors, a signal fusion sensor, a means for signal demodulation, and a means for automatic modulation classification. An output of the signal fusion sensor is sent to a means for modulation scheme classification to select the appropriate demodulation technique for demodulating the unknown signal and provide the necessary intelligence about the monitored signals to the user and allow the user to simulate the unknown non-cooperative signal. The present invention also contemplates a multi-sensor signal fusion article of manufacture with a storage medium encoded with machine-readable computer program code for more accurate descriptions of monitored signals and methods for achieving higher accuracy descriptions of monitored signals in a non-cooperative environment with multi-sensor non-cooperative demodulation.
FILED Wednesday, December 14, 2011
APPL NO 13/325124
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/340
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295412 O'Neal
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jeremy R. O'Neal (West Warwick, Rhode Island)
ABSTRACT An apparatus and method for signal detection in which a digital sample stream is fed round robin into a plurality of buffers, which are sequentially compared with a reference signal to determine a match. A processor determines the chronological order of the samples in each bit of each buffer, and directs a bitwise comparison between the signal in each buffer with the reference to determine a match, e.g., by correlation. The apparatus and method are preferably implemented with a Field-Programmable Gate Array (FPGA). This scheme permits real time correlation of a data stream with a reference without use of shift registers, or a significant number of dedicated logic blocks.
FILED Thursday, September 30, 2010
APPL NO 12/894625
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/343
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295655 Manipatruni et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York)
INVENTOR(S) Sasikanth Manipatruni (Ithaca, New York);  Qianfan Xu (Houston, Texas);  Michal Lipson (Ithaca, New York)
ABSTRACT An optical modulator includes a ring resonator with a waveguide adjacent to and optically coupled to the micro-ring resonator. A p-i-n junction is formed about the ring resonator. An optional additional doped region may be formed opposite the waveguide from the ring resonator and when combined with the p-i-n junction forms a nearly closed p-i-n junction about the ring resonator. The ring resonator may be a silicon micro-ring resonator. Multiple different resonant frequency resonators may be coupled to the waveguide along with different detectors to multiplex light on the waveguide. The spectrum of the resonator may be controlled by an applied voltage. A prepulsing device may be used to enhance electrical transitions to enhance the speed of the modulator.
FILED Friday, August 24, 2007
APPL NO 12/310431
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295708 Bandyopadhyay
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Promode R. Bandyopadhyay (Middletown, Rhode Island)
ABSTRACT An underwater data transmission system including arrays of nano-meter scaled photon emitters and sensors on an outer surface of an underwater platform. For the emitters, a laser is pulsed to correlate with data packets, providing a beam of photons at a prescribed frequency. Nano-scaled collecting lenses channel the incoming photons to photo-receptors located at a focal plane for the frequency at the base of each lens. A coating on the lenses absorbs photons at the frequency that are not aligned with the longitudinal axes of the lenses or tubes. Nano-wires connect the photo-receptors to a light intensity integrator. The integrator integrates the intensity over a surface area. The output of the integrator is fed to a signal processor to track and process the arriving digital packets.
FILED Thursday, June 16, 2011
APPL NO 13/161898
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Optical communications
398/131
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US 08296053 Brennan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Edward M. Brennan (Wenonah, New Jersey);  Carl V. Jannetti (Huntingdon Valley, Pennsylvania);  John B. Stetson (New Hope, Pennsylvania)
ABSTRACT A system and method are disclosed for determining relative motion between ship-based combat system elements using accelerometers. Relative motion between combat system elements can introduce error into the targeting information provided to the weapons system, and thus the system facilitates compensation for such relative motion. The system includes accelerometers mounted on radar systems, inertial navigation system (INS) sensors, and weapons systems. An algorithm is disclosed in which the raw accelerometer signals are filtered, then combined with ship INS attitude signals in a displacement calculation module (DCM). Within the DCM, the signals are manipulated to calculate, for each combat system element, the translational and rotational displacements due to hull modal vibration and the translational and rotational displacements due to force vibration. The sum of these values represent the movement of each of the affected combat system elements. Relative motion between elements is calculated simply as the difference between the calculated movement values for each element.
FILED Tuesday, October 09, 2007
APPL NO 11/869283
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/300
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US 08296127 Marcu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Daniel Marcu (Hermosa Beach, California);  Dragos Stefan Munteanu (Culver City, California)
ABSTRACT A translation training device which extracts from two nonparallel Corpora a set of parallel sentences. The system finds parameters between different sentences or phrases, in order to find parallel sentences. The parallel sentences are then used for training a data-driven machine translation system. The process can be applied repetitively until sufficient data is collected or until the performance of the translation system stops improving.
FILED Tuesday, March 22, 2005
APPL NO 11/087376
ART UNIT 2626 — Selective Visual Display Systems
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/5
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US 08296773 Bose et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Pradip Bose (Yorktown Heights, New York);  Alper Buyuktosunoglu (White Plains, New York);  Eren Kursun (Ossining, New York)
ABSTRACT A system and method for improving efficiency of a multi-core architecture includes, in accordance with a workload, determining a number of cores to shut down based upon a metric that combines parameters to represent operational efficiency. Threads of the workload are reassigned to cores remaining active by assigning threads based on priority constraints and thread execution history to improve the operational efficiency of the multi-core architecture.
FILED Monday, June 30, 2008
APPL NO 12/164775
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Virtual machine task or process management or task management/control
718/105
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US 08296839 Sax et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) William C. Sax (McLean, Virginia);  William Wollman (Oceanport, New Jersey);  Egil H. Jegers (Eatontown, New Jersey)
ABSTRACT Methods and systems for enabling robust routing between protected enclaves over an unsecured network are provided herein. In one aspect, the present invention provides methods and systems for enabling routing among a plurality of protected enclaves, each supported by one or more secure gateways, over an unsecured network. Methods and systems according to the present invention achieve key routing requirements while presenting solutions that can be readily scaled to large network environments. In another aspect, the present invention provides methods and systems for implementing a Prefix Discovery Server (PDS) that enables the mapping of Plain Text (PT) networks to secure gateways, maintains current network routing information, and assists VPN gateways in determining routes to remote protected enclaves.
FILED Tuesday, June 06, 2006
APPL NO 11/447092
ART UNIT 2432 — Cryptography and Security
CURRENT CPC
Information security
726/15
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Department of Health and Human Services (HHS) 

US 08292812 Feleppa et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Riverside Research Institute (New York, New York)
INVENTOR(S) Ernest J. Feleppa (Rye, New York);  Jonathan Mamou (New York, New York)
ABSTRACT The present invention provides a method for detecting and locating brachytherapy seeds using Singular Spectrum Analysis (SSA). The method exploits the presence of seed-specific repetitive echo signals in detecting seeds and determining their location. Radio frequency (rf) echo signals received from a scanned area of interest are converted to zero-mean envelope-detected signals and then processed using SSA to produce a spectral-power line (a P line). The P line indicates the relative likelihood of a seed being present. A colored P-mode image derived from a set of P lines is superimposed on a conventional ultrasound B-mode image to depict seed location.
FILED Friday, December 21, 2007
APPL NO 12/004670
ART UNIT 3737 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Surgery
6/437
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US 08292814 Insana et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Michael F. Insana (Urbana, Illinois);  Marko Orescanin (Urbana, Illinois);  Kathleen Toohey (Urbana, Illinois)
ABSTRACT A system includes an acoustic radiation force source that is structured to generate an acoustic radiation force at one or more frequencies. A shear wave transmission device is embedded in a mass including a biologic material. The shear wave transmission device is responsive to the acoustic radiation force source to transmit shear waves through the biologic material. A Doppler ultrasonic device detects the shear waves and generates data representative of the shear waves. A processing device determines one or more mechanical properties of the biologic material from the data.
FILED Tuesday, December 01, 2009
APPL NO 12/592717
ART UNIT 3737 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Surgery
6/438
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293004 Chow et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) ADA Foundation (Chicago, Illinois)
INVENTOR(S) Laurence C. Chow (Germantown, Maryland);  Shozo Takagi (Gaithersburg, Maryland)
ABSTRACT This study reports in vitro and in vivo properties of fluorapatite (FA)-forming calcium phosphate cements (CPCs). Experimental cements contained from (0 to 3.1) mass % of F, corresponding to presence of FA at levels of approximately (0 to 87) mass %. The crystallinity of the apatitic cement product increased greatly with the FA content. When implanted subcutaneously in rats, the in vivo resorption rate decreased significantly with increasing FA content. The cement with the highest FA content was not resorbed in soft tissue, making it biocompatible and bioinert CPC. These bioinert CPCs are candidates for use in useful applications where slow or no resorption of the implant is required to achieve the desired clinical outcome.
FILED Friday, July 01, 2011
APPL NO 13/175368
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compositions: Coating or plastic
16/690
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US 08293061 DeVoe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) University of Maryland College Park (College Park, Maryland)
INVENTOR(S) Donald Lad DeVoe (Bethesda, Maryland);  Chia-Wen Tsao (Columbia, Maryland)
ABSTRACT The present invention relates to a method for bonding two surfaces to one another. The invention particularly pertains to the use of such method in which one of the surfaces is a polymeric plastic (and more preferably a polymeric thermoplastic (especially poly-(methyl methacrylate) (“PMMA”) or cyclic olefin copolymer (“COC”)). More particularly, the invention relates to treating at least one of the contacting surfaces with UV in the presence of oxygen to thereby generate ozone (O3) and atomic oxygen under conditions of temperature below that of the glass transition temperature of the polymeric plastic. The UV/O3-mediated bonding results in high bond strength and zero-deformation method. This bonding method can be applied to micro/nano-scale polymer devices, and particularly to microfluidic devices, for a low cost, high throughput, high yield advantage.
FILED Friday, March 06, 2009
APPL NO 12/399178
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/273.300
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US 08293083 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Henry S White (Salt Lake City, Utah);  Bo Zhang (Salt Lake City, Utah);  Ryan J White (Salt Lake City, Utah);  Eric N Ervin (Salt Lake City, Utah);  Gangli Wang (Salt Lake City, Utah)
ABSTRACT Provided are fabrication, characterization and application of a nanodisk electrode, a nanopore electrode and a nanopore membrane. These three nanostructures share common fabrication steps. In one embodiment, the fabrication of a disk electrode involves sealing a sharpened internal signal transduction element (“ISTE”) into a substrate, followed by polishing of the substrate until a nanometer-sized disk of the ISTE is exposed. The fabrication of a nanopore electrode is accomplished by etching the nanodisk electrode to create a pore in the substrate, with the remaining ISTE comprising the pore base. Complete removal of the ISTE yields a nanopore membrane, in which a conical shaped pore is embedded in a thin membrane of the substrate.
FILED Thursday, November 18, 2010
APPL NO 12/949469
ART UNIT 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/420
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US 08293187 Venditti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Charles P. Venditti (Kensington, Maryland);  Randy Chandler (Washington, District of Columbia)
ABSTRACT The invention provides a device including a chamber wherein the chamber including a rigid enclosure; a rigid lid for the enclosure; a gasket between the lid and the enclosure to allow for an airtight seal between the enclosure and the gasket upon closure of a latch connecting the enclosure and the lid; a port for airtight attachment of a syringe, and a port for airtight insertion of a gas sensor. The device can further include a gas sensor and one or more syringes for attachment to the device by a three-way stopcocks. The device is appropriately sized for use with the subject of interest. The invention also provides methods for use of the device.
FILED Monday, April 06, 2009
APPL NO 12/418795
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/401
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293224 Bzik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) David Bzik (Grantham, New Hampshire);  Barbara Fox (Grantham, New Hampshire)
ABSTRACT Uracil auxotroph mutants of apicomplexans are provided which lack a functional carbamoyl phosphate synthase II (CPSII) enzyme. Also provided are T. gondii autoxtroph mutants which express exogenous antigens, and methods of protecting an animal against a T. gondii and non-T. gondii disease.
FILED Friday, December 21, 2007
APPL NO 11/962584
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293240 Newell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Martha Karen Newell (Colorado Springs, Colorado);  Evan Newell (Menlo Park, California);  Elizabeth Villalobos-Menuey (Monument, Colorado)
ABSTRACT Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a UCP and/or Fas antibody or other inhibitor, or combination thereof, and a therapeutically acceptable amount of a fatty acid metabolism inhibitor and/or a therapeutically acceptable amount of a glucose metabolism inhibitor, optionally in combination with one or more chemotherpeutic agents. In preferred embodiments, the invention combines an antibody against UCP and/or Fas antigen with an oxirane carboxylic acid, represented by etomoxir, and/or with a 2-deoxyglucose compound, represented by 2-deoxy-D-glucose. The systems and methods of the invention can be used to treat drug-resistant or multi-drug resistant cancers.
FILED Monday, February 23, 2009
APPL NO 12/390753
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/146.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293245 Smith et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland)
INVENTOR(S) Michael Smith (Silver Spring, Maryland);  Angela Melton-Celsa (Sterling, Virginia);  Alison O'Brien (Bethesda, Maryland)
ABSTRACT The invention is based on the discovery of the epitope in the Stx1 protein for the 13C4 antibody. The invention features non-full length Stx1 polypeptides that include the epitope for the 13C4 monoclonal antibody epitope. The invention also features methods of producing anti-Stx1 antibodies specific for the 13C4 epitope of the Stx1 protein. Additionally, the invention features methods for treating a subject having, or at risk of developing, a Shiga toxin associated disease (e.g., hemolytic uremia syndrome and diseases associated with E. coli and S. dysenteriae infection) with a polypeptide that includes the 13C4 epitope or with an anti-Stx1 antibody developed using the methods of the invention. Furthermore, the invention features the detection of Stx1 in a sample using the antibodies developed using the methods of the invention.
FILED Friday, April 20, 2007
APPL NO 11/788546
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/192.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293247 Hoffmann et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) St. Jude Children's Research Hospital (Memphis, Tennessee)
INVENTOR(S) Erich Hoffmann (Galveston, Texas);  Aleksandr S. Lipatov (Atlanta, Georgia);  Richard J. Webby (Memphis, Tennessee);  Elena A. Govorkova (Cordova, Tennessee);  Robert G. Webster (Memphis, Tennessee)
ABSTRACT The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines.
FILED Thursday, December 09, 2010
APPL NO 12/964491
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/206.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293248 Vilalta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Vical Incorporated (San Diego, California);  The University of Washington (Seattle, Washington)
INVENTOR(S) Adrian Vilalta (San Diego, California);  Michal Margalith (Solana Beach, California);  Lichun Dong (Seattle, Washington);  David Koelle (Seattle, Washington)
ABSTRACT This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from herpes simplex virus. Also disclosed are therapeutic compositions useful in such a method.
FILED Friday, October 16, 2009
APPL NO 12/581058
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/231.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293477 Glimcher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Cornell University (Itacha, New York)
INVENTOR(S) Laurie H. Glimcher (West Newton, Massachusetts);  Dallas C. Jones (Brookline, Massachusetts);  Marc Wein (Brookline, Massachusetts)
ABSTRACT This invention demonstrates that KRC molecules have multiple important functions as modulating agents in regulating a wide variety of cellular processes including bone formation and mineralization. TGF-β signaling in osteoblasts promotes the formation of a multimeric complex between KRC, Runx2, Smad3, and the E3 ubiquitin ligase, WWP1 which inhibits Runx2 function due to the ability of WWP1 to promote Runx2 polyubiquitination and proteasome-dependent degradation. Furthermore, KRC and WWP1 form a complex with RSK2 which promotes RSK2 phosphorylation and inhibits RSK2 function due to the ability of WWP 1 to promote RSK2 ubiquitination. Methods for identifying modulators of KRC activity are provided. Methods for modulating an immune response, bone formation and mineralization, and KRC-associated disorders using agents that modulate KRC expression and/or activity are also provided.
FILED Friday, April 14, 2006
APPL NO 11/918503
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293479 Torday et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center (Torrance, California)
INVENTOR(S) John S. Torday (Redondo Beach, California);  Virender K. Rehan (Torrance, California);  Richard Mink (Torrance, California)
ABSTRACT This invention pertains to the discovery that Parathyroid Hormone-related Protein (PTHrP) can be detect and/or stage, and/or treat chronic lung diseases. In particular, it was discovered that PTHrP levels in broncho-alveolar lavage are indicative of lung “health” and “disease”, and can be used to predict lung disease in patients at risk of chronic lung disease and/or to evaluate the efficacy of a ventilation regime.
FILED Thursday, May 01, 2003
APPL NO 10/513474
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293481 Brozovich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Frank V. Brozovich (Rochester, Minnesota);  Frank C. Chen (Rochester, Minnesota);  Robert P. Frantz (Rochester, Minnesota);  Ozgur Ogut (Rochester, Minnesota)
ABSTRACT Materials and methods for using biomarkers to determine prognosis and response to treatment in subjects having chronic vascular dysfunction.
FILED Friday, November 02, 2007
APPL NO 12/514275
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293486 Kaplan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Tissue Engineering Resource Center (TERC)
APPLICANT(S)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) David L. Kaplan (Concord, Massachusetts);  Xiaoqin Wang (Winchester, Massachusetts);  Monica A. Serban (Melrose, Massachusetts)
ABSTRACT The present invention provides for compositions and methods of linking silk fibroin to active agents through the specific interaction between avidin and biotin, providing for functionalization of silk-based protein biomaterials. An avidin- or biotin-modified silk is a biomaterial platform for functionalization with a variety of correspondingly linked active agents, such as antibodies and growth factors. A variety of functionalized silk materials, such as silk hydrogel, silk micro/nanoparticles and silk films, can be prepared by the methods of the present invention. The functionalization strategies of the present invention are relatively easy, fast and feasible, and are thus useful in many biomedical applications.
FILED Tuesday, July 20, 2010
APPL NO 13/381687
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293495 Shusta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Eric V. Shusta (Madison, Wisconsin);  Christian Weidenfeller (Madison, Wisconsin);  Clive Niels Svendsen (Madison, Wisconsin)
ABSTRACT A method of creating a multicellular blood-brain barrier model is disclosed. In one embodiment, the method comprises culturing primary brain microvascular endothelial cells or embryonic stem cell-derived endothelial cells upon a permeable support in the presence of neural progenitor cells.
FILED Thursday, August 25, 2011
APPL NO 13/218123
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/29
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293498 Dermody et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Terence S. Dermody (Brentwood, Tennessee);  Takeshi Kobayashi (Kyoto, Japan);  James D. Chappell (Nashville, Tennessee)
ABSTRACT The present invention provides methods for the generation of viable reoviruses using only cloned nucleic acid segments representing the RNA segments of the reovirus genome.
FILED Wednesday, December 19, 2007
APPL NO 11/960357
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293501 Fredriksson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Johan Erik Simon Fredriksson (Uppsala, Sweden);  Carl Oscar Fredrik Dahl (Menlo Park, California)
ABSTRACT Methods and compositions for performing low background multiplex nucleic acid amplification reactions are provided. Aspects of the invention include contacting a nucleic acid sample with two or more primer pairs for two or more target nucleic acids under template dependent primer extension reaction conditions, e.g., polymerase chain reaction (PCR) conditions. The resultant amplified composition is then contacted with target nucleic acid circularizing reagents, and product circularized target nucleic acids are then selected, e.g., for further amplification. Also provided are systems and kits that find use in practicing embodiments of the inventions.
FILED Tuesday, September 11, 2007
APPL NO 12/440716
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293510 Detamore et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Michael Detamore (Lawrence, Kansas);  Stevin H. Gehrke (Lawrence, Kansas)
ABSTRACT The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living cells, such as chondrocytes, encapsulated therein. In a preferred aspect, the physically cross-linked polymer is selected from the group consisting of thermally gelling polysaccharides and proteins, such as agarose or gelatin, and the chemically cross-linked or physically entangled polymer is synthesized from a water-soluble vinyl monomer, either as a homopolymer or copolymer, such as polyethylene glycol diacrylate (“PEG-DA”) and 2-hydroxyethyl methacrylate (“HEMA”).
FILED Friday, November 16, 2007
APPL NO 11/985707
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/178
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293513 Brown et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Milton L. Brown (Brookeville, Maryland);  Mira O. Jung (Rockville, Maryland);  Anatoly Dritschilo (Bethesda, Maryland);  Yali Kong (Centreville, Virginia)
ABSTRACT Novel histone deacetylase inhibitors, including novel fluorescent histone deacetylase inhibitors, are described. Methods for making and using the same, e.g., to treat cancer, are provided.
FILED Friday, December 12, 2008
APPL NO 12/747365
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/184
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293517 Cunningham
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Philip R. Cunningham (Troy, Michigan)
ABSTRACT The “instant evolution” system was initially developed in E. coli, primarily because of the ease with which this organism can be genetically manipulated. Because many of the functionally important regions of rRNA are conserved among bacteria, drug leads developed against conserved targets in the E. coli system may produce broad-spectrum anti-infectives. However, in order the develop a system to product narrow-spectrum anti-infectives, herein we disclose method and compositions for screening Pseudomonas aeruginosa 16S rRNA in E. coli cells. In certain embodiments, a plasmid comprising the 16S rRNA gene from Pseudomonas aeruginosa t mutated to replace the natural helix 9 region with the corresponding region of the E. coli rRNA, is shown to form functional ribosomes in E. coli host cells. Li other embodiments, a plasmid, comprising the unmutated 16S rRNA from Pseudomonas aeruginosa, along with a plasmid containing the Pseudomonas aeruginosa S20 protein, can yield functional ribosomes in E. coli cells.
FILED Thursday, May 11, 2006
APPL NO 11/914062
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.330
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293524 Ionescu-Zanetti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) Fluxion Biosciences Inc. (San Francisco, California)
INVENTOR(S) Cristian Ionescu-Zanetti (Berkeley, California);  Michelle Khine (San Francisco, California);  Michael Schwartz (San Francisco, California);  Andrew Blatz (San Mateo, California)
ABSTRACT Apparatus and methods are provided for analysis of individual particles in a microfluidic device. The methods involve the immobilization of an array of particles in suspension and the application of experimental compounds. Such methods can also include electrophysiology studies including patch clamp recording, electroporation, or both in the same microfluidic device. The apparatus provided includes a microfluidic device coupled to a multi-well structure and an interface for controlling the flow of media within the microchannel device.
FILED Sunday, March 25, 2007
APPL NO 11/690831
ART UNIT 1775 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/297.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293720 Thompson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)
ASSIGNEE(S) Dogwood Pharmaceuticals, Inc. (Charlottesville, Virginia)
INVENTOR(S) Robert D Thompson (Charlottesville, Virginia);  Anthony Beauglehole (Charlottesville, Virginia);  Frank Schmidtmann (Charlottesville, Virginia);  Jayson M. Rieger (Charlottesville, Virginia)
ABSTRACT The present invention provides substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters and pharmaceutical compositions containing the same that are selective agonists of A2A adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
FILED Thursday, December 18, 2008
APPL NO 12/338369
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/46
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293724 Kunos et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) George Kunos (Bethesda, Maryland);  Alexandros Makriyannis (Watertown, Massachusetts)
ABSTRACT Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the degradation of oleamide (an endogenous sleep-inducing lipid) and anandamide (an endogenous ligand for cannabinoid receptors). Disclosed herein are potent inhibitors of FAAH and methods for their use for treating a variety of disorder, including hypertension and cardiac hypertrophy.
FILED Tuesday, April 06, 2010
APPL NO 12/755227
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/64
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293725 Berkman
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Cancer Targeted Technology LLC (San Francisco, California)
INVENTOR(S) Cliff Berkman (San Francisco, California)
ABSTRACT Compounds of the formula, A-L-B, wherein A is glutamate or a glutamate analog; L is a phosphoramidate or a phosphoramidate analog; and B is serine or a serine analog are described which are potent inhibitors of prostate-specific membrane antigen (PMSA). Such compounds are useful in treatment of prostate cancer; and when chemically attached to a fluorescent dye, can efficiently and selectively label prostate cancer cells for fluorescent imaging.
FILED Friday, January 22, 2010
APPL NO 12/691957
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/114
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293776 Teitelbaum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Daniel H. Teitelbaum (Ann Arbor, Michigan);  Hollis Showalter (Ann Arbor, Michigan);  Scott Larsen (South Lyon, Michigan);  Peter Lucas (Ann Arbor, Michigan);  Hiroyuki Koga (Tokyo, Japan)
ABSTRACT The present invention provides compositions and methods for treating inflammatory conditions (e.g., of the bowel). In particular, the present invention provides methods of treating (e.g., therapeutically and/or prophylactically treating) inflammatory conditions (e.g., of the bowel), compositions useful for such methods (e.g., antagonists and/or inhibitors of angiotensin II (AngII) receptor Type 1a (AT1a)), and methods of identifying, characterizing and/or optimizing such compositions. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine) and research applications.
FILED Wednesday, August 05, 2009
APPL NO 12/536390
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/381
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293800 Meier et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) Santhera Pharmaceuticals (Schweiz) AG (Liestal, Switzerland);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Thomas Meier (Basel, Switzerland);  Bibiana Bielekova (Kensington, Maryland);  Henry F. McFarland (Gaithersburg, Maryland)
ABSTRACT The present invention relates to approaches, methods, pharmaceuticals and uses directed to the curative treating or preventing of Primary Progressive Multiple Sclerosis (PP-MS), by using 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (Idebenone) as the active agent.
FILED Wednesday, April 28, 2010
APPL NO 12/768930
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/689
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293867 Messersmith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Phillip B. Messersmith (Clarendon Hills, Illinois);  Haeshin Lee (Chicago, Illinois);  Yuhan Lee (Daejeon, South Korea);  Zhongqiang Liu (Evanston, Illinois);  Lesley Hamming (Durham, North Carolina)
ABSTRACT The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.
FILED Monday, November 10, 2008
APPL NO 12/267822
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
528/424
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293872 Raines et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Ronald T. Raines (Madison, Wisconsin);  George N. Phillips, Jr. (Madison, Wisconsin);  R. Jeremy Johnson (Middleton, Wisconsin);  Jason G. McCoy (Madison, Wisconsin)
ABSTRACT This invention relates to cytotoxic variants of human ribonuclease 1 (RNase 1) identified through analysis of the interaction between RNase 1 and the human ribonuclease inhibitor (hRI) as defined by the three dimensional (3-D) atomic structure of the RNase1 hRI complex. Also disclosed is the 3-D structure of the hRI•RNase 1 complex and methods for designing the RNase 1 variants.
FILED Friday, September 23, 2011
APPL NO 13/243373
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293880 Cote et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Richard J. Cote (Miami, Florida);  Anirban P. Mitra (Los Angeles, California)
ABSTRACT The present invention relates to methods of prognosing urothelial carcinoma. In one embodiment, the present invention provides a method of prognosing urothelial carcinoma by determining expression levels of JUN, MAP2K6, STAT3 and/or ICAM1. In another embodiment, the present invention provides an single prognostic panel made up of eight gene markers. In another embodiment, the present invention provides a single prognostic panel made up of eleven gene markers.
FILED Wednesday, March 25, 2009
APPL NO 12/411199
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293920 Myers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Andrew G. Myers (Boston, Massachusetts);  Jason D. Brubaker (Cheshire, Connecticut)
ABSTRACT The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides a more efficient route for preparing the enone intermediate.
FILED Wednesday, March 09, 2011
APPL NO 13/043742
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/243
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294092 Reed et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S) Yale University (New Haven, Connecticut);  UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Mark A. Reed (Monroe, Connecticut);  Predrag S. Krstic (Knoxville, Tennessee);  Weihua Guan (New Haven, Connecticut);  Xiongce Zhao (Gaithersburg, Maryland)
ABSTRACT A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed.
FILED Tuesday, March 23, 2010
APPL NO 12/730226
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/292
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294461 Overall et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) William R. Overall (Palo Alto, California);  Greig C. Scott (Palo Alto, California)
ABSTRACT A method for detecting coupled RF current magnetic resonance (MR) objects in a body and determining MR risk is provided. The body is scanned with reverse circularly polarized RF. MR signals generated by coupling of the reverse circularly polarized RF with the RF current MR objects are detected. The detected MR signals are used to determine a risk value.
FILED Thursday, January 15, 2009
APPL NO 12/354451
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/309
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296076 Fan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Hei-Mun Christina Fan (Fremont, California);  Stephen R. Quake (Stanford, California)
ABSTRACT Disclosed is a method to achieve digital quantification of DNA (i.e., counting differences between identical sequences) using direct shotgun sequencing followed by mapping to the chromosome of origin and enumeration of fragments per chromosome. The preferred method uses massively parallel sequencing, which can produce tens of millions of short sequence tags in a single run and enabling a sampling that can be statistically evaluated. By counting the number of sequence tags mapped to a predefined window in each chromosome, the over- or under-representation of any chromosome in maternal plasma DNA contributed by an aneuploid fetus can be detected. This method does not require the differentiation of fetal versus maternal DNA. The median count of autosomal values is used as a normalization constant to account for differences in total number of sequence tags is used for comparison between samples and between chromosomes.
FILED Friday, April 20, 2012
APPL NO 13/452083
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/20
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 08291654 Botkin et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)
ASSIGNEE(S) SunPower Corporation (San Jose, California)
INVENTOR(S) Jonathan Botkin (El Cerrito, California);  Simon Graves (Berkeley, California);  Matt Danning (Oakland, California);  Matthew Culligan (Berkeley, California)
ABSTRACT A PV module kit for non-penetrating rooftop installation, including a plurality of PV modules and a plurality of connectors. Each of the PV modules includes a PV laminate and a frame forming a mounting region assembled thereto. The connectors include a male connector having a male fastener extending from a head, and a female connector having a female fastener assembled within a head. The heads are entirely formed of plastic. The kit provides a mounted array state including a junction at which the mounting region of at least two of the PV modules are aligned and interconnected by engagement of the male connector with the female connector. The so-formed junction is substantially electrically insulated. The plurality of connectors can further include a spacer connector including a head forming a bore sized to slidably receive the male fastener, with all of the connector heads being identical.
FILED Wednesday, October 12, 2011
APPL NO 13/272056
ART UNIT 3633 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/173.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291694 Gonze et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations LLC (, None)
INVENTOR(S) Eugene V. Gonze (Pinckney, Michigan);  Michael J. Paratore, Jr. (Howell, Michigan)
ABSTRACT An exhaust system that processes exhaust generated by an engine is provided. The system generally includes a particulate filter (PF) that filters particulates from the exhaust wherein an upstream end of the PF receives exhaust from the engine. A grid of electrically resistive material is applied to an exterior upstream surface of the PF and selectively heats exhaust passing through the grid to initiate combustion of particulates within the PF. A catalyst coating applied to at least one of the PF and the grid. A control module estimates a temperature of the grid and controls the engine to produce a desired exhaust product to increase the temperature of the grid.
FILED Wednesday, December 05, 2007
APPL NO 11/950576
ART UNIT 3748 — Static Structures, Supports and Furniture
CURRENT CPC
Power plants
060/286
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291705 York
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) William David York (Greer, South Carolina)
ABSTRACT A fuel nozzle for a combustor includes a mixing passage through which fluid is directed toward a combustion area and a plurality of swirler vanes disposed in the mixing passage. Each swirler vane of the plurality of swirler vanes includes at least one fuel hole through which fuel enters the mixing passage in an injection direction substantially parallel to an outer surface of the plurality of swirler vanes thereby decreasing a flameholding tendency of the fuel nozzle. A method of operating a fuel nozzle for a combustor includes flowing a fluid through a mixing passage past a plurality of swirler vanes and injecting a fuel into the mixing passage in an injection direction substantially parallel to an outer surface of the plurality of swirler vanes.
FILED Wednesday, August 13, 2008
APPL NO 12/190918
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/737
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291824 Welle et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Eric J. Welle (Niceville, Florida);  Paul T. Vianco (Albuquerque, New Mexico);  Paul S. Headley (Cedar Crest, New Mexico);  Jason A. Jarrell (Rio Rancho, New Mexico);  J. Emmett Garrity (Albuquerque, New Mexico);  Keegan P. Shelton (Sandia Park, New Mexico);  Stephen K. Marley (Tijeras, New Mexico)
ABSTRACT A monolithic exploding foil initiator (EFI) or slapper detonator and the method for making the monolithic EFI wherein the exploding bridge and the dielectric from which the flyer will be generated are integrated directly onto the header. In some embodiments, the barrel is directly integrated directly onto the header.
FILED Thursday, July 08, 2010
APPL NO 12/832097
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/202.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291872 Szybist et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) James P. Szybist (Knoxville, Tennessee);  James C. Conklin (Knoxville, Tennessee)
ABSTRACT A six-stroke engine cycle having improved efficiency. Heat is recovered from the engine combustion gases by using a 6-stroke engine cycle in which combustion gases are partially vented proximate the bottom-dead-center position of the fourth stroke cycle, and water is injected proximate the top-dead-center position of the fourth stroke cycle.
FILED Friday, June 12, 2009
APPL NO 12/483388
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Internal-combustion engines
123/64
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292492 Ho et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Clifford K. Ho (Albuquerque, New Mexico);  Susan J. Altman (Cedar Crest, New Mexico);  Paul G. Clem (Albuquerque, New Mexico);  Michael Hibbs (Albuquerque, New Mexico);  Adam W. Cook (Albuquerque, New Mexico)
ABSTRACT An array of airfoil-shaped micro-mixers that enhances fluid mixing within permeable membrane channels, such as used in reverse-osmosis filtration units, while minimizing additional pressure drop. The enhanced mixing reduces fouling of the membrane surfaces. The airfoil-shaped micro-mixer can also be coated with or comprised of biofouling-resistant (biocidal/germicidal) ingredients.
FILED Tuesday, November 11, 2008
APPL NO 12/268542
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Agitating
366/341
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292580 Schiavo et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) Anthony L. Schiavo (Oviedo, Florida);  Malberto F. Gonzalez (Orlando, Florida);  Kuangwei Huang (Singapore, Singapore);  David C. Radonovich (Cranberry Township, Pennsylvania)
ABSTRACT A metal vane core or strut (64) is formed integrally with an outer backing plate (40). An inner backing plate (38) is formed separately. A spring (74) with holes (75) is installed in a peripheral spring chamber (76) on the strut. Inner and outer CMC shroud covers (46, 48) are formed, cured, then attached to facing surfaces of the inner and outer backing plates (38, 40). A CMC vane airfoil (22) is formed, cured, and slid over the strut (64). The spring (74) urges continuous contact between the strut (64) and airfoil (66), eliminating vibrations while allowing differential expansion. The inner end (88) of the strut is fastened to the inner backing plate (38). A cooling channel (68) in the strut is connected by holes (69) along the leading edge of the strut to peripheral cooling paths (70, 71) around the strut. Coolant flows through and around the strut, including through the spring holes.
FILED Friday, June 05, 2009
APPL NO 12/479047
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/96.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292583 Marra
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) John J. Marra (Winter Springs, Florida)
ABSTRACT A turbine blade is provided for a gas turbine comprising: a support structure comprising a base defining a root of the blade and a framework extending radially outwardly from the base, and an outer skin coupled to the support structure framework. The skin has a generally constant thickness along substantially the entire radial extent thereof. The framework and the skin define an airfoil of the blade.
FILED Thursday, August 13, 2009
APPL NO 12/540430
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/97.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292974 Chen et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Zonghai Chen (Bolingbrook, Illinois);  Khalil Amine (Oakbrook, Illinois);  Ilias Belharouak (Bolingbrook, Illinois)
ABSTRACT A method includes modifying a surface of an electrode active material including providing a solution or a suspension of a surface modification agent; providing the electrode active material; preparing a slurry of the solution or suspension of the surface modification agent, the electrode active material, a polymeric binder, and a conductive filler; casting the slurry in a metallic current collector; and drying the cast slurry.
FILED Wednesday, February 15, 2012
APPL NO 13/397319
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal working
029/623.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292987 Gonze et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations LLC (, None)
INVENTOR(S) Eugene V. Gonze (Pinckney, Michigan);  Michael J. Paratore, Jr. (Howell, Michigan);  Kevin W. Kirby (Calabasas Hills, California);  Amanda Phelps (Malibu, California);  Daniel J. Gregoire (Thousand Oaks, California)
ABSTRACT A system includes a particulate matter (PM) filter with an upstream end for receiving exhaust gas, a downstream end and zones. The system also includes a heating element. A control module selectively activates the heating element to inductively heat one of the zones.
FILED Friday, September 12, 2008
APPL NO 12/209298
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Gas separation: Processes
095/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293089 James et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Conrad D. James (Albuquerque, New Mexico);  Paul C. Galambos (Albuquerque, New Mexico);  Mark S. Derzon (Albuquerque, New Mexico);  Darin C. Graf (Albuquerque, New Mexico);  Kenneth R. Pohl (Albuquerque, New Mexico);  Chris J. Bourdon (Albuquerque, New Mexico)
ABSTRACT Systems and methods for combining dielectrophoresis, magnetic forces, and hydrodynamic forces to manipulate particles in channels formed on top of an electrode substrate are discussed. A magnet placed in contact under the electrode substrate while particles are flowing within the channel above the electrode substrate allows these three forces to be balanced when the system is in operation. An optical detection scheme using near-confocal microscopy for simultaneously detecting two wavelengths of light emitted from the flowing particles is also discussed.
FILED Monday, November 02, 2009
APPL NO 12/610409
ART UNIT 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/643
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293135 Cox et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Gerald P. Cox (Brockport, New York);  Cathy A. Fromen (Raleigh, North Carolina);  Kenneth L. Marshall (Rochester, New York);  Stephen D. Jacobs (Pittsford, New York)
ABSTRACT A PCLC flake/fluid host suspension that enables dual-frequency, reverse drive reorientation and relaxation of the PCLC flakes is composed of a fluid host that is a mixture of: 94 to 99.5 wt % of a non-aqueous fluid medium having a dielectric constant value ∈, where 1<∈<7, a conductivity value σ, where 10−9>σ>10−7 Siemens per meter (S/m), and a resistivity r, where 107>r>1010 ohm-meters (Ω-m), and which is optically transparent in a selected wavelength range Δλ; 0.0025 to 0.25 wt % of an inorganic chloride salt; 0.0475 to 4.75 wt % water; and 0.25 to 2 wt % of an anionic surfactant; and 1 to 5 wt % of PCLC flakes suspended in the fluid host mixture. Various encapsulation forms and methods are disclosed including a Basic test cell, a Microwell, a Microcube, Direct encapsulation (I), Direct encapsulation (II), and Coacervation encapsulation. Applications to display devices are disclosed.
FILED Wednesday, July 21, 2010
APPL NO 12/840474
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compositions
252/299.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293329 Forrest
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Solid-State Lighting Program (SSL)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan)
ABSTRACT An organic vapor jet printing system includes a pump for increasing the pressure of an organic flux.
FILED Friday, February 20, 2009
APPL NO 12/389628
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/255.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293385 Hassan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) The University of Southern California (Los Angeles, California)
INVENTOR(S) Azad M. Hassan (Los Angeles, California);  Mark E. Thompson (Anaheim, California)
ABSTRACT Organic electronic devices comprising a phthalimide compound. The phthalimide compounds disclosed herein are electron transporters with large HOMO-LUMO gaps, high triplet energies, large reduction potentials, and/or thermal and chemical stability. As such, these phthalimide compounds are suitable for use in any of various organic electronic devices, such as OLEDs and solar cells. In an OLED, the phthalimide compounds may serve various functions, such as a host in the emissive layer, as a hole blocking material, or as an electron transport material. In a solar cell, the phthalimide compounds may serve various functions, such as an exciton blocking material. Various examples of phthalimide compounds which may be suitable for use in the present invention are disclosed.
FILED Wednesday, August 11, 2010
APPL NO 12/854297
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/690
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293426 Weil et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) K. Scott Weil (Richland, Washington);  Kerry D. Meinhardt (Kennewick, Washington);  Vincent L. Sprenkle (Richland, Washington)
ABSTRACT Solid-oxide fuel cell (SOFC) stack assembly designs are consistently investigated to develop an assembly that provides optimal performance, and durability, within desired cost parameters. A new design includes a repeat unit having a SOFC cassette and being characterized by a three-component construct. The three components include an oxidation-resistant, metal window frame hermetically joined to an electrolyte layer of a multi-layer, anode-supported ceramic cell and a pre-cassette including a separator plate having a plurality of vias that provide electrical contact between an anode-side collector within the pre-cassette and a cathode-side current collector of an adjacent cell. The third component is a cathode-side seal, which includes a standoff that supports a cathode channel spacing between each of the cassettes in a stack. Cassettes are formed by joining the pre-cassette and the window frame.
FILED Tuesday, September 30, 2008
APPL NO 12/242165
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/519
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293535 Farquar et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) George Roy Farquar (Livermore, California);  Roald N. Leif (San Ramon, California)
ABSTRACT A bio-threat simulant that includes a carrier and DNA encapsulated in the carrier. Also a method of making a simulant including the steps of providing a carrier and encapsulating DNA in the carrier to produce the bio-threat simulant.
FILED Thursday, October 21, 2010
APPL NO 12/909428
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/8
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293566 Kim et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Jin K. Kim (Albuquerque, New Mexico);  Malcolm S. Carroll (Albuquerque, New Mexico);  Aaron Gin (Albuquerque, New Mexico);  Phillip F. Marsh (Lowell, Massachusetts);  Erik W. Young (Albuquerque, New Mexico);  Michael J. Cich (Albuquerque, New Mexico)
ABSTRACT An infrared focal plane array (FPA) is disclosed which utilizes a strained-layer superlattice (SLS) formed of alternating layers of InAs and InxGa1-xSb with 0≦x≦0.5 epitaxially grown on a GaSb substrate. The FPA avoids the use of a mesa structure to isolate each photodetector element and instead uses impurity-doped regions formed in or about each photodetector for electrical isolation. This results in a substantially-planar structure in which the SLS is unbroken across the entire width of a 2-D array of the photodetector elements which are capped with an epitaxially-grown passivation layer to reduce or eliminate surface recombination. The FPA has applications for use in the wavelength range of 3-25 μm.
FILED Tuesday, June 15, 2010
APPL NO 12/815714
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/93
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293780 Gakh et al.
FUNDED BY
Department of Energy (DOE)
Non-Profit Organization (NPO)
National Academy of Sciences
APPLICANT(S)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Andrei A Gakh (Bethesda, Maryland);  Mykhaylo V. Vovk (Kyiv, Ukraine);  Nina V. Mel'nychenko (Kyiv, Ukraine);  Volodymyr A. Sukach (Brovary, Ukraine)
ABSTRACT The present disclosure relates to novel compounds having the structural Formulas (1a,1b), stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or pharmaceutically acceptable salt and/or solvate thereof as chemotherapy agents for treating of cancer, particularly androgen-independent prostate cancer. The disclosure also relates to methods for preparing said compounds, and to pharmaceutical compositions comprising said compounds.
FILED Friday, March 16, 2012
APPL NO 13/422158
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/394
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294022 Lenox
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)
ASSIGNEE(S) SunPower Corporation (San Jose, California)
INVENTOR(S) Carl J. S. Lenox (Oakland, California)
ABSTRACT A photovoltaic array including a plurality of photovoltaic assemblies and a plurality of mounting units. The mounting units each include an elongate rail and a plurality of leg assemblies. The rail is sized and configured to maintain a portion of at least two of the photovoltaic assemblies, with the leg assemblies extending from the rail in a spaced-apart fashion and terminating in a foot for placement against a rooftop structure for minimally penetration installation. Further, at least one of the leg assemblies can include a retractable leg. When the photovoltaic array is installed to a rooftop structure including a membrane intermittently secured to a rooftop deck, the retractable leg accommodates upward billowing of the membrane under windy conditions.
FILED Wednesday, April 01, 2009
APPL NO 12/416358
ART UNIT 1728 — Organic Chemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/246
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294092 Reed et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S)
ASSIGNEE(S) Yale University (New Haven, Connecticut);  UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Mark A. Reed (Monroe, Connecticut);  Predrag S. Krstic (Knoxville, Tennessee);  Weihua Guan (New Haven, Connecticut);  Xiongce Zhao (Gaithersburg, Maryland)
ABSTRACT A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed.
FILED Tuesday, March 23, 2010
APPL NO 12/730226
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/292
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294141 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
APPLICANT(S)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Zhong L. Wang (Marietta, Georgia);  Changshi Lao (Atlanta, Georgia);  Jun Zhou (Atlanta, Georgia)
ABSTRACT An ultraviolet light sensor includes an elongated metal oxide nanostructure, a layer of an ultraviolet light-absorbing polymer, a current source and a current detector. The elongated metal oxide nanostructure has a first end and an opposite second end. The layer of an ultraviolet light-absorbing polymer is disposed about at least a portion of the metal oxide nanostructure. The current source is configured to provide electrons to the first end of the metal oxide nanostructure. The current detector is configured to detect an amount of current flowing through the metal oxide nanostructure. The amount of current flowing through the metal oxide nanostructure corresponds to an amount of ultraviolet light impinging on the metal oxide nanostructure.
FILED Tuesday, July 07, 2009
APPL NO 12/498605
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294321 Hsu
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) John S. Hsu (Oak Ridge, Tennessee)
ABSTRACT An apparatus is provided having a cylindrical stator and a rotor that is spaced from a stator to define an annular primary air gap that receives AC flux from the stator. The rotor has a plurality of longitudinal pole portions disposed parallel to the axis of rotation and alternating in polarity around a circumference of the rotor. Each longitudinal pole portion includes portions of permanent magnet (PM) material and at least one of the longitudinal pole portions has a first end and an opposing second end and a side magnet is disposed adjacent the first end and a side pole is disposed adjacent the second end.
FILED Thursday, May 05, 2011
APPL NO 13/101241
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/156.640
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294616 Ormesher et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Richard C. Ormesher (Albuquerque, New Mexico);  Douglas L. Bickel (Albuquerque, New Mexico)
ABSTRACT The location of a land-based radio frequency (RF) emitter is determined from an airborne platform. RF signaling is received from the RF emitter via first and second antennas. In response to the received RF signaling, signal samples for both antennas are produced and processed to determine the location of the RF emitter.
FILED Thursday, September 30, 2010
APPL NO 12/894402
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications: Directive radio wave systems and devices
342/449
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294645 Shiyanovskii et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Kent State University (Kent, Ohio)
INVENTOR(S) Sergij V. Shiyanovskii (Stow, Ohio);  Mingxia Gu (San Jose, California);  Oleg D. Lavrentovich (Kent, Ohio)
ABSTRACT The invention provides a liquid crystal device and method thereof. Subsequent to applying a first electrical voltage on a liquid crystal to induce a reorientation of the liquid crystal, a second electrical voltage with proper polarity is applied on the liquid crystal to assist the relaxation of the reorientation that was induced by the first electrical voltage. The “switch-off” phase of the liquid crystal can therefore be accelerated or temporally shortened, and the device can exhibit better performance such as fast response to on/off signals. The invention can be widely used LCD, LC shutter, LC lens, spatial light modulator, telecommunication device, tunable filter, beam steering device, and electrically driven LC device, among others.
FILED Thursday, March 12, 2009
APPL NO 12/403160
ART UNIT 2629 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Computer graphics processing and selective visual display systems
345/87
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294886 Diver, Jr.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Richard B. Diver, Jr. (Albuquerque, New Mexico)
ABSTRACT The present invention is directed to an improved method for establishing camera fixture location for aligning mirrors on a solar collector array (SCA) comprising multiple mirror modules. The method aligns the mirrors on a module by comparing the location of the receiver image in photographs with the predicted theoretical receiver image location. To accurately align an entire SCA, a common reference is used for all of the individual module images within the SCA. The improved method can use relative pixel location information in digital photographs along with alignment fixture inclinometer data to calculate relative locations of the fixture between modules. The absolute locations are determined by minimizing alignment asymmetry for the SCA. The method inherently aligns all of the mirrors in an SCA to the receiver, even with receiver position and module-to-module alignment errors.
FILED Tuesday, January 19, 2010
APPL NO 12/689798
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/138
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295910 Weisenberger et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Thomas Jefferson National Accelerator Facility (TJNAF)
Federally Funded Research and Development Center (FFRDC)
Operated by Jefferson Science Associates, LLC (JSA) at Newport News, VA
APPLICANT(S)
ASSIGNEE(S) Jefferson Science Associates, LLC (Newport News, Virginia)
INVENTOR(S) Andrew G. Weisenberger (Yorktown, Virginia);  Stanislaw Majewski (Yorktown, Virginia)
ABSTRACT A method for in-situ monitoring both the balloon/cavity and the radioactive source in brachytherapy treatment utilizing using at least one pair of miniature gamma cameras to acquire separate images of: 1) the radioactive source as it is moved in the tumor volume during brachytherapy; and 2) a relatively low intensity radiation source produced by either an injected radiopharmaceutical rendering cancerous tissue visible or from a radioactive solution filling a balloon surgically implanted into the cavity formed by the surgical resection of a tumor.
FILED Friday, November 16, 2007
APPL NO 11/985680
ART UNIT 3737 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Surgery
6/424
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296078 Pfeifer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Kent B. Pfeifer (Los Lunas, New Mexico);  William G. Yelton (Sandia Park, New Mexico);  Dayle R. Kerr (Sandia Park, New Mexico);  Francis A. Bouchier (Albuquerque, New Mexico)
ABSTRACT A method of multi-dimensional moment analysis for the characterization of signal peaks can be used to optimize the operation of an analytical system. With a two-dimensional Péclet analysis, the quality and signal fidelity of peaks in a two-dimensional experimental space can be analyzed and scored. This method is particularly useful in determining optimum operational parameters for an analytical system which requires the automated analysis of large numbers of analyte data peaks. For example, the method can be used to optimize analytical systems including an ion mobility spectrometer that uses a temperature stepped desorption technique for the detection of explosive mixtures.
FILED Thursday, June 25, 2009
APPL NO 12/491733
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/24
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296430 Blocksome et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael A. Blocksome (Rochester, Minnesota);  Douglas R. Miller (Albert Lea, Minnesota)
ABSTRACT Methods, systems, and products are disclosed for administering an epoch initiated for remote memory access that include: initiating, by an origin application messaging module on an origin compute node, one or more data transfers to a target compute node for the epoch; initiating, by the origin application messaging module after initiating the data transfers, a closing stage for the epoch, including rejecting any new data transfers after initiating the closing stage for the epoch; determining, by the origin application messaging module, whether the data transfers have completed; and closing, by the origin application messaging module, the epoch if the data transfers have completed.
FILED Monday, June 18, 2007
APPL NO 11/764333
ART UNIT 2441 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/225
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296457 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles J. Archer (Rochester, Minnesota);  Ahmad A. Faraj (Rochester, Minnesota);  Todd A. Inglett (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota)
ABSTRACT Methods, apparatus, and products are disclosed for providing nearest neighbor point-to-point communications among compute nodes of an operational group in a global combining network of a parallel computer, each compute node connected to each adjacent compute node in the global combining network through a link, that include: identifying each link in the global combining network for each compute node of the operational group; designating one of a plurality of point-to-point class routing identifiers for each link such that no compute node in the operational group is connected to two adjacent compute nodes in the operational group with links designated for the same class routing identifiers; and configuring each compute node of the operational group for point-to-point communications with each adjacent compute node in the global combining network through the link between that compute node and that adjacent compute node using that link's designated class routing identifier.
FILED Thursday, August 02, 2007
APPL NO 11/832955
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/238
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296590 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles J. Archer (Rochester, Minnesota);  Michael A. Blocksome (Rochester, Minnesota);  Amanda E. Peters (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota);  Brian E. Smith (Rochester, Minnesota)
ABSTRACT Methods, apparatus, and products are disclosed for budget-based power consumption for application execution on a plurality of compute nodes that include: assigning an execution priority to each of one or more applications; executing, on the plurality of compute nodes, the applications according to the execution priorities assigned to the applications at an initial power level provided to the compute nodes until a predetermined power consumption threshold is reached; and applying, upon reaching the predetermined power consumption threshold, one or more power conservation actions to reduce power consumption of the plurality of compute nodes during execution of the applications.
FILED Monday, June 09, 2008
APPL NO 12/135593
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Support
713/320
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08293061 DeVoe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S)
ASSIGNEE(S) University of Maryland College Park (College Park, Maryland)
INVENTOR(S) Donald Lad DeVoe (Bethesda, Maryland);  Chia-Wen Tsao (Columbia, Maryland)
ABSTRACT The present invention relates to a method for bonding two surfaces to one another. The invention particularly pertains to the use of such method in which one of the surfaces is a polymeric plastic (and more preferably a polymeric thermoplastic (especially poly-(methyl methacrylate) (“PMMA”) or cyclic olefin copolymer (“COC”)). More particularly, the invention relates to treating at least one of the contacting surfaces with UV in the presence of oxygen to thereby generate ozone (O3) and atomic oxygen under conditions of temperature below that of the glass transition temperature of the polymeric plastic. The UV/O3-mediated bonding results in high bond strength and zero-deformation method. This bonding method can be applied to micro/nano-scale polymer devices, and particularly to microfluidic devices, for a low cost, high throughput, high yield advantage.
FILED Friday, March 06, 2009
APPL NO 12/399178
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/273.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293083 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Henry S White (Salt Lake City, Utah);  Bo Zhang (Salt Lake City, Utah);  Ryan J White (Salt Lake City, Utah);  Eric N Ervin (Salt Lake City, Utah);  Gangli Wang (Salt Lake City, Utah)
ABSTRACT Provided are fabrication, characterization and application of a nanodisk electrode, a nanopore electrode and a nanopore membrane. These three nanostructures share common fabrication steps. In one embodiment, the fabrication of a disk electrode involves sealing a sharpened internal signal transduction element (“ISTE”) into a substrate, followed by polishing of the substrate until a nanometer-sized disk of the ISTE is exposed. The fabrication of a nanopore electrode is accomplished by etching the nanodisk electrode to create a pore in the substrate, with the remaining ISTE comprising the pore base. Complete removal of the ISTE yields a nanopore membrane, in which a conical shaped pore is embedded in a thin membrane of the substrate.
FILED Thursday, November 18, 2010
APPL NO 12/949469
ART UNIT 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Chemistry: Electrical and wave energy
24/420
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293354 Fu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Peng-Fei Fu (Midland, Michigan);  Lingjie Jay Guo (Ann Arbor, Michigan)
ABSTRACT Radiation-curable silsesquioxane resin materials are employed for micro- and nanolithography. The resin materials can include a radiation-curable silsesquioxane resin and a photo-initiator having low viscosity. The low viscosity of the liquid system allows imprinting with low pressure and low temperature; e.g. room temperature. The resist's dry etching resistance is increased and the cured film is more easily separated from the mask. Due to its high modulus after cure, the material allows the fabrication of micro- and nano-features having high aspect ratios while providing a high throughput. Various pattern sizes, for example, ranging from tens of microns to as small as a few nanometers, may be achieved with the UV-curable material system.
FILED Thursday, April 09, 2009
APPL NO 12/421333
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Stock material or miscellaneous articles
428/141
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293470 Quake et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Stephen Quake (Stanford, California);  Hei-Mun Christina Fan (Fremont, California)
ABSTRACT The present methods are exemplified by a process in which maternal blood containing fetal DNA is diluted to a nominal value of approximately 0.5 genome equivalent of DNA per reaction sample. Digital PCR is then be used to detect aneuploidy, such as the trisomy that causes Down Syndrome. Since aneuploidies do not present a mutational change in sequence, and are merely a change in the number of chromosomes, it has not been possible to detect them in a fetus without resorting to invasive techniques such as amniocentesis or chorionic villi sampling. Digital amplification allows the detection of aneuploidy using massively parallel amplification and detection methods, examining, e.g., 10,000 genome equivalents.
FILED Tuesday, June 15, 2010
APPL NO 12/815647
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293471 Gregg et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Marshall University Research Corporation (Huntington, West Virginia)
INVENTOR(S) Derek A. Gregg (Barboursville, West Virginia);  Elizabeth E. Murray (Huntington, West Virginia);  Michael L. Norton (Huntington, West Virginia);  Justin T. Swick (Chesapeake, Ohio);  Herbert Tesser (Huntington, West Virginia)
ABSTRACT A thermal cycle system and method suitable for mass production of DNA comprising a temperature control body having at least two sectors. Each sector has at least one heater, cooler, or other means for changing temperature. A path traverses the sectors in a cyclical fashion. In use, a piece of tubing or other means for conveying is placed along the path and a reaction mixture is pumped or otherwise moved along the path such that the reaction mixture is repetitively heated or cooled to varying temperatures as the reaction mixture cyclically traverses the sectors. The reaction mixture thereby reacts to form a product. In particular, polymerase chain reaction reactants may continuously be pumped through the tubing to amplify DNA. The temperature control body is preferably a single aluminum cylinder with a grooved channel circling around its exterior surface, and preferably has wedge-shaped or pie-shaped sectors separated by a thermal barrier.
FILED Friday, January 28, 2005
APPL NO 11/045526
ART UNIT 1775 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.120
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293510 Detamore et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas)
INVENTOR(S) Michael Detamore (Lawrence, Kansas);  Stevin H. Gehrke (Lawrence, Kansas)
ABSTRACT The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living cells, such as chondrocytes, encapsulated therein. In a preferred aspect, the physically cross-linked polymer is selected from the group consisting of thermally gelling polysaccharides and proteins, such as agarose or gelatin, and the chemically cross-linked or physically entangled polymer is synthesized from a water-soluble vinyl monomer, either as a homopolymer or copolymer, such as polyethylene glycol diacrylate (“PEG-DA”) and 2-hydroxyethyl methacrylate (“HEMA”).
FILED Friday, November 16, 2007
APPL NO 11/985707
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/178
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293868 King et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Glenn F. King (Chapel Hill, Australia);  Brianna Sollod McFarland (Windsor, Colorado);  Graham Nicholson (Chatswood West, Australia);  Simon Gunning (Auckland Central, New Zealand)
ABSTRACT A family of insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Also included are polynucleotides and expression vectors encoding the polypeptides and insect viruses and cells expressing the polypeptides. Transgenic plants and insects expressing the insecticidal polypeptides are also described. The insecticidal polypeptides may be employed in methods and compositions for treating insects, insect larvae, and plants.
FILED Monday, January 17, 2011
APPL NO 13/007841
ART UNIT 1638 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293920 Myers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Andrew G. Myers (Boston, Massachusetts);  Jason D. Brubaker (Cheshire, Connecticut)
ABSTRACT The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides a more efficient route for preparing the enone intermediate.
FILED Wednesday, March 09, 2011
APPL NO 13/043742
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/243
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US 08294137 Jain et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Faquir Chand Jain (Storrs, Connecticut);  Evan Heller (Glastonbury, Connecticut)
ABSTRACT A field-effect transistor is provided and includes source, gate and drain regions, where the gate region controls charge carrier location in the transport channel, the transport channel includes a asymmetric coupled quantum well layer, the asymmetric quantum well layer includes at least two quantum wells separated by a barrier layer having a greater energy gap than the wells, the transport channel is connected to the source region at one end, and the drain regions at the other, the drain regions include at least two contacts electrically isolated from each other, the contacts are connected to at least one quantum well. The drain may include two regions that are configured to form the asymmetric coupled well transport channel. In an embodiment, two sources and two drains are also envisioned.
FILED Monday, January 04, 2010
APPL NO 12/655609
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/24
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294898 Qu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S)
ASSIGNEE(S) Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Dongxia Qu (Princeton, New Jersey);  Claire Gmachl (Princeton, New Jersey)
ABSTRACT The present invention relates to a rotationally asymmetric chaotic optical multi-pass cavity useful in optical gas sensing spectroscopy, optical delay lines, and laser amplification systems, for example. The cavity may include a single closed mirror having a light reflective surface that is deformed in two orthogonal directions and more particularly, but not exclusively, in the shape of a quadrupole in both horizontal and vertical planes. The cavity includes a light entry port and a light exit port which may be the same or separate ports, as well as a gas inlet and a gas outlet. The optical path length, the beam divergence rate, and the spot pattern are controlled by selecting the cavity deformation coefficients and the input beam direction to achieve the desired beam path and beam quality.
FILED Monday, August 25, 2008
APPL NO 12/197558
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/437
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294982 Her
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) University of North Carolina at Charlotte (Charlotte, North Carolina)
INVENTOR(S) Tsinghua Her (Charlotte, North Carolina)
ABSTRACT A fiber, such as a photonic bandgap fiber, is provided, the fiber including a core and a cladding. The core can extend longitudinally and can have a gain medium configured to provide laser amplification to laser radiation propagating along the core. For example, the gain medium may include a dopant configured to provide amplification, when activated by one or more modes of excitation radiation, of laser radiation propagating along said core. The cladding can be radially exterior to the core, and can be configured to provide a low-loss propagation the one or more modes of excitation radiation and a lossy propagation of all modes of laser radiation along the core, the lossy propagation higher than the low-loss propagation, in particular when the one or more modes of excitation radiation is substantially absent from the core. Associated methods and apparatuses are also provided.
FILED Thursday, July 08, 2010
APPL NO 12/832583
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Optical: Systems and elements
359/341.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296842 Singh et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Sumeet Singh (San Francisco, California);  George Varghese (San Diego, California);  Cristi Estan (La Jolla, California);  Stefan Savage (Carlsbad, California)
ABSTRACT Network worms or viruses are a growing threat to the security of public and private networks and the individual computers that make up those networks. A content sifting method if provided that automatically generates a precise signature for a worm or virus that can then be used to significantly reduce the propagation of the worm elsewhere in the network or eradicate the worm altogether. The content sifting method is complemented by a value sampling method that increases the throughput of network traffic that can be monitored. Together, the methods track the number of times invariant strings appear in packets and the network address dispersion of those packets including variant strings. When an invariant string reaches a particular threshold of appearances and address dispersion, the string is reported as a signature for suspected worm.
FILED Wednesday, December 01, 2004
APPL NO 11/547944
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Information security
726/22
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296861 Gerton
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Jordan M. Gerton (Salt Lake City, Utah)
ABSTRACT Methods and systems for improving high resolution imaging using a polarization-modulated tip enhanced optical microscope. A polarizer is configured to alternately create and remove a region of enhanced optical intensity adjacent the tip of the microscope probe at the focus of a light source. The sample being studied emits photons at specific rates relative to a background rate depending on the existence or nonexistence of the region of enhanced optical intensity. Comparing the rate of emissions when the region of enhanced optical intensity exists to when it does not creates a detailed image of the sample. By not requiring the probe to oscillate, this system enhances the resolution of the microscope without potentially causing damage to the sample.
FILED Thursday, August 06, 2009
APPL NO 12/536974
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM]
850/33
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 08291776 Pickens et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Herman L. Pickens (Gurley, Alabama);  James A. Richard (Grant, Alabama)
ABSTRACT A force sensor includes a magnetostrictive material and a magnetic field generator positioned in proximity thereto. A magnetic field is induced in and surrounding the magnetostrictive material such that lines of magnetic flux pass through the magnetostrictive material. A sensor positioned in the vicinity of the magnetostrictive material measures changes in one of flux angle and flux density when the magnetostrictive material experiences an applied force that is aligned with the lines of magnetic flux.
FILED Wednesday, June 30, 2010
APPL NO 12/827515
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/862.690
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08291788 Ihrke et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan);  The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Chris A. Ihrke (Hartland, Michigan);  Joshua S. Mehling (League City, Texas);  Adam H. Parsons (Tulsa, Oklahoma);  Bryan Kristian Griffith (Webster, Texas);  Nicolaus A. Radford (League City, Texas);  Frank Noble Permenter (Webster, Texas);  Donald R. Davis (Brighton, Michigan);  Robert O. Ambrose (Houston, Texas);  Lucien Q. Junkin (Houston, Texas)
ABSTRACT A rotary actuator assembly is provided for actuation of an upper arm assembly for a dexterous humanoid robot. The upper arm assembly for the humanoid robot includes a plurality of arm support frames each defining an axis. A plurality of rotary actuator assemblies are each mounted to one of the plurality of arm support frames about the respective axes. Each rotary actuator assembly includes a motor mounted about the respective axis, a gear drive rotatably connected to the motor, and a torsion spring. The torsion spring has a spring input that is rotatably connected to an output of the gear drive and a spring output that is connected to an output for the joint.
FILED Tuesday, September 22, 2009
APPL NO 12/564090
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Machine element or mechanism
074/490.50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08292217 Smith et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Thomas R. Smith (Westminster, California);  Angel M. Espinosa (St. Charles, Missouri);  Daniel J. Farrell (St. Louis, Missouri);  Andrew Robertson (West Sayville, New York);  John C. Leylegian (White Plains, New York);  Jason S. Tyll (Blue Point, New York);  Florin Girlea (Flushing, New York);  Joseph A. Alifano (Ronkonkoma, New York);  Randy S. M. Chue (Bohemia, New York)
ABSTRACT Hypersonic inlet systems and methods are disclosed. In one embodiment, an inlet for an airbreathing propulsion system includes an inboard surface at least partially shaped to conform to a plurality of streamline-traces of a design flowfield approaching an aperture, an outboard surface spaced apart from the inboard surface, an upper surface extending between the inboard and outboard surfaces, and a lower surface extending between the inboard and outboard surfaces, wherein leading edges of the inboard, outboard, upper, and lower surfaces cooperatively define the aperture.
FILED Wednesday, June 04, 2008
APPL NO 12/133289
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeronautics and astronautics
244/53.B00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293168 Chen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S) Gang Chen (Carlisle, Massachusetts);  Mildred Dresselhaus (Arlington, Massachusetts);  Zhifeng Ren (Newton, Massachusetts)
ABSTRACT The present invention is generally directed to nanocomposite thermoelectric materials that exhibit enhanced thermoelectric properties. The nanocomposite materials include two or more components, with at least one of the components forming nano-sized structures within the composite material. The components are chosen such that thermal conductivity of the composite is decreased without substantially diminishing the composite's electrical conductivity. Suitable component materials exhibit similar electronic band structures. For example, a band-edge gap between at least one of a conduction band or a valence band of one component material and a corresponding band of the other component material at interfaces between the components can be less than about 5kBT, wherein kB is the Boltzman constant and T is an average temperature of said nanocomposite composition.
FILED Wednesday, November 19, 2008
APPL NO 12/273783
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Powder metallurgy processes
419/52
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08293178 Roberson et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Luke B. Roberson (Titusville, Florida);  Janine E. Captain (Titusville, Florida);  Martha K. Williams (Titusville, Florida);  Trent M. Smith (Melbourne, Florida);  LaNetra Clayton Tate (Oviedo, Florida)
ABSTRACT A chemochromic sensor for detecting a combustible gas, such as hydrogen, includes a chemochromic pigment mechanically mixed with a polymer and formed into a rigid or pliable material. In a preferred embodiment, the chemochromic detector includes aerogel material. The detector is robust and easily modifiable for a variety of applications and environmental conditions, such as atmospheres of inert gas, hydrogen gas, or mixtures of gases, or in environments that have variable temperature, including high temperatures such as above 100° C. and low temperatures such as below −196° C.
FILED Tuesday, November 06, 2007
APPL NO 11/935545
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/94
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294989 Park et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Yeonjoon Park (Yorktown, Virginia);  Sang H. Choi (Poquoson, Virginia);  Glen C. King (Williamsburg, Virginia);  James R. Elliott (Versuvius, Virginia)
ABSTRACT An optical apparatus includes an optical diffraction device configured for diffracting a predetermined wavelength of incident light onto adjacent optical focal points, and a photon detector for detecting a spectral characteristic of the predetermined wavelength. One of the optical focal points is a constructive interference point and the other optical focal point is a destructive interference point. The diffraction device, which may be a micro-zone plate (MZP) of micro-ring gratings or an optical lens, generates a constructive ray point using phase-contrasting of the destructive interference point. The ray point is located between adjacent optical focal points. A method of generating a densely-accumulated ray point includes directing incident light onto the optical diffraction device, diffracting the selected wavelength onto the constructive interference focal point and the destructive interference focal point, and generating the densely-accumulated ray point in a narrow region.
FILED Thursday, July 30, 2009
APPL NO 12/512344
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/565
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295081 Campbell
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Boise State University (Boise, Idaho)
INVENTOR(S) Kristy A. Campbell (Boise, Idaho)
ABSTRACT Non-volatile memory devices with two stacked layers of chalcogenide materials comprising the active memory device have been investigated for their potential as phase-change memories. The devices tested included GeTe/SnTe, Ge2Se3/SnTe, and Ge2Se3/SnSe stacks. All devices exhibited resistance switching behavior. The polarity of the applied voltage with respect to the SnTe or SnSe layer was critical to the memory switching properties, due to the electric field induced movement of either Sn or Te into the Ge-chalcogenide layer. One embodiment of the invention is a device comprising a stack of chalcogenide-containing layers which exhibit phase-change switching only after a reverse polarity voltage potential is applied across the stack causing ion movement into an adjacent layer and thus “activating” the device to act as a phase-change random access memory device or a reconfigurable electronics device when the applied voltage potential is returned to the normal polarity. Another embodiment of the invention is a device that is capable of exhibiting more than two data states.
FILED Tuesday, April 12, 2011
APPL NO 13/085265
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/163
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08295342 Chen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
John C. Stennis Space Center (SSC)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Jun Chen (Hamilton, Canada);  Dake He (Yorktown Heights, New York);  Ashish Jagmohan (Irvington, New York);  Ligang Lu (New City, New York);  Vadim Sheinin (Yorktown Heights, New York)
ABSTRACT Disclosed are a method and system for video compression, wherein the video encoder has low computational complexity and high compression efficiency. The disclosed system comprises a video encoder and a video decoder, wherein the method for encoding includes the steps of converting a source frame into a space-frequency representation; estimating conditional statistics of at least one vector of space-frequency coefficients; estimating encoding rates based on the said conditional statistics; and applying Slepian-Wolf codes with the said computed encoding rates. The preferred method for decoding includes the steps of; generating a side-information vector of frequency coefficients based on previously decoded source data, encoder statistics, and previous reconstructions of the source frequency vector; and performing Slepian-Wolf decoding of at least one source frequency vector based on the generated side-information, the Slepian-Wolf code bits and the encoder statistics.
FILED Wednesday, November 14, 2007
APPL NO 11/939882
ART UNIT 2477 — Multiplex and VoIP
CURRENT CPC
Pulse or digital communications
375/240.10
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 08293004 Chow et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)
ASSIGNEE(S) ADA Foundation (Chicago, Illinois)
INVENTOR(S) Laurence C. Chow (Germantown, Maryland);  Shozo Takagi (Gaithersburg, Maryland)
ABSTRACT This study reports in vitro and in vivo properties of fluorapatite (FA)-forming calcium phosphate cements (CPCs). Experimental cements contained from (0 to 3.1) mass % of F, corresponding to presence of FA at levels of approximately (0 to 87) mass %. The crystallinity of the apatitic cement product increased greatly with the FA content. When implanted subcutaneously in rats, the in vivo resorption rate decreased significantly with increasing FA content. The cement with the highest FA content was not resorbed in soft tissue, making it biocompatible and bioinert CPC. These bioinert CPCs are candidates for use in useful applications where slow or no resorption of the implant is required to achieve the desired clinical outcome.
FILED Friday, July 01, 2011
APPL NO 13/175368
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compositions: Coating or plastic
16/690
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294007 Shenoy et al.
FUNDED BY
Department of Commerce (DOC)
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia);  The United States of America, as represented by the Secretary of Commerce (Washington, District of Columbia)
INVENTOR(S) Devanand K. Shenoy (McLean, Virginia);  Alok Singh (Springfield, Virginia);  William R. Barger (Cobb Island, Maryland);  John J. Kasianowicz (Darnestown, Maryland)
ABSTRACT A membrane is disclosed made from a compound having a hydrophilic head group, an aliphatic tail group, and a polymerizable functional group. The membrane spans an aperture and may be polymerized. The membrane may be useful for DNA sequencing when the membrane includes an ion channel.
FILED Monday, February 28, 2005
APPL NO 11/070398
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Nanotechnology
977/713
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294567 Stell
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) Williams-Pyro, Inc. (Fort Worth, Texas)
INVENTOR(S) Andrew W Stell (Aledo, Texas)
ABSTRACT A method and system are provided, which provides reliable fire detection. In one implementation, the automated system includes a combination of sensors configured to measure various factors associated with a hazard, such as a fire or gas leakage, and generate sensor readings. Factors measured can include smoke, carbon monoxide and heat. The system further includes a detection device that is configured to determine whether a hazard or fire exists by performing a fuzzy analysis of sensor readings. The fuzzy analysis includes categorizing respective sensor readings into fuzzy sets, and determining whether the hazard exists based on a combination of the categorizations. In addition the size and direction of a fire can be determined from multiple sensors.
FILED Tuesday, April 12, 2011
APPL NO 13/084796
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/522
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296842 Singh et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Sumeet Singh (San Francisco, California);  George Varghese (San Diego, California);  Cristi Estan (La Jolla, California);  Stefan Savage (Carlsbad, California)
ABSTRACT Network worms or viruses are a growing threat to the security of public and private networks and the individual computers that make up those networks. A content sifting method if provided that automatically generates a precise signature for a worm or virus that can then be used to significantly reduce the propagation of the worm elsewhere in the network or eradicate the worm altogether. The content sifting method is complemented by a value sampling method that increases the throughput of network traffic that can be monitored. Together, the methods track the number of times invariant strings appear in packets and the network address dispersion of those packets including variant strings. When an invariant string reaches a particular threshold of appearances and address dispersion, the string is reported as a signature for suspected worm.
FILED Wednesday, December 01, 2004
APPL NO 11/547944
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Information security
726/22
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08294525 Bulzacchelli et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) John Francis Bulzacchelli (Yorktown Heights, New York);  Zeynep Toprak Deniz (Yorktown Heights, New York);  Daniel Joseph Friedman (Yorktown Heights, New York);  Shahrzad Naraghi (Austin, Texas);  Alexander V Rylyakov (Yorktown Heights, New York)
ABSTRACT Apparatuses and methods are provided relating to a voltage controlled oscillator (VCO) based on current starved inverting delay stages; wherein in each stage a PMOS transistor as header and an NMOS transistor as footer are used with their gate-to-source voltages always equal to analog control voltage. The analog control voltage is also used as the supply voltage of the oscillator. An exemplary apparatus includes a VCO of n stages, where n is an odd number and where each stage includes a current starved inverter where the analog control voltage is also used as the supply voltage of each delay stage.
FILED Friday, June 18, 2010
APPL NO 12/818790
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Oscillators
331/57
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08296168 Subrahmanian et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Venkatramanan Siva Subrahmanian (Potomac, Maryland);  Diego Recupero Reforgiato (Hyattsville, Maryland);  Antonio Picariello (Montefredane, Italy);  Bonnie J. Dorr (Laurel, Maryland);  Carmine Cesarano (Somma Vesuviana, Italy);  Amelia Sagoff (Bethesda, Maryland)
ABSTRACT System and method for analysis of an opinion expressed in documents on a particular topic computes opinion strength on a continuous numeric scale, or qualitatively. A variety of opinion scoring techniques are plugged in to score opinion expressing words and sentences in documents. These scores are aggregated to measure the opinion intensity of documents. Multilingual opinion analysis is supported by capability to concurrently identify and visualize the opinion intensity expressed in documents in multiple languages. A multi-dimensional representation of the measured opinion intensity is generated which is agreeable with multi-lingual domain.
FILED Friday, June 08, 2007
APPL NO 11/808278
ART UNIT 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/7.110
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 08292192 Purswell et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Joseph L. Purswell (Starkville, Mississippi);  Berry D. Lott (Starkville, Mississippi);  Matthew Darr (Ames, Iowa)
ABSTRACT The automated humidity control system controls the humidity within a setter hall. The system continuously monitors the existing setter hall thermal conditions and electronically compares the existing conditions to computerized data describing the targeted conditions. The system then takes action to conform the existing condition to the targeted condition.
FILED Tuesday, May 26, 2009
APPL NO 12/471847
ART UNIT 3784 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Automatic temperature and humidity regulation
236/44.C00
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 08296075 Den Hartog
FUNDED BY
Department of Justice (DOJ)
Federal Bureau of Investigation (FBI)
APPLICANT(S)
ASSIGNEE(S) Mito Tech, LLC (Santa Fe, New Mexico)
INVENTOR(S) Bobi Den Hartog (Santa Fe, New Mexico)
ABSTRACT The present invention relates to a computer system and methods of computer-facilitated data analysis for providing reliable DNA alignments. More specifically, the invention relates to the automation of alignment and naming of mitochondrial DNA sequences for use in forensic analysis. The methods of the present invention provide consistency of sequence nomenclature by minimizing alignment ambiguities, thus providing a common functional system within and among laboratories.
FILED Wednesday, May 20, 2009
APPL NO 12/469035
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/20
VIEW PATENT @ USPTO:  Full Text   PDF 

Federal Reserve Bank (FED) 

US 08296223 Breeden, Jr. et al.
FUNDED BY
Federal Reserve Bank (FED)
APPLICANT(S)
ASSIGNEE(S) Federal Reserve Bank of Atlanta (Atlanta, Georgia);  Federal Reserve Bank of Cleveland (Cleveland, Ohio);  Federal Reserve Bank of Richmond (Richmond, Virginia);  Federal Reserve Bank of Kansas City (Kansas City, Missouri)
INVENTOR(S) Benjamin T. Breeden, Jr. (Eldersburg, Maryland);  Steven D. Martin (Parma, Ohio);  Timothy Rachek (Chagrin Falls, Ohio);  Randall Lee Mueller (Kansas City, Missouri);  V. Srinivas Nori (Norcross, Georgia);  Daniel A. Maslaney (Norcross, Georgia)
ABSTRACT Processing duplicate items in image cash letter (“ICL”) reversal files for efficient handling. A duplicate item processing module can receive ICL reversal files comprising items representing duplicate electronic checks. The duplicate item processing module can determine whether the processing entity erroneously presented the item more than once. The duplicate item processing module can also determine whether the depositing institution erroneously deposited the item more than once for processing. Based on the determination of the source of the error, the duplicate item processing module can make a correction in its own records and/or forward the ICL reversal file with the duplicate item to the receiving institution.
FILED Tuesday, November 06, 2007
APPL NO 11/982923
ART UNIT 3694 — Business Methods - Finance/Banking/ Insurance
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/38
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 08293780 Gakh et al.
FUNDED BY
Department of Energy (DOE)
Non-Profit Organization (NPO)
National Academy of Sciences
APPLICANT(S)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Andrei A Gakh (Bethesda, Maryland);  Mykhaylo V. Vovk (Kyiv, Ukraine);  Nina V. Mel'nychenko (Kyiv, Ukraine);  Volodymyr A. Sukach (Brovary, Ukraine)
ABSTRACT The present disclosure relates to novel compounds having the structural Formulas (1a,1b), stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or pharmaceutically acceptable salt and/or solvate thereof as chemotherapy agents for treating of cancer, particularly androgen-independent prostate cancer. The disclosure also relates to methods for preparing said compounds, and to pharmaceutical compositions comprising said compounds.
FILED Friday, March 16, 2012
APPL NO 13/422158
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/394
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 08293517 Cunningham
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Philip R. Cunningham (Troy, Michigan)
ABSTRACT The “instant evolution” system was initially developed in E. coli, primarily because of the ease with which this organism can be genetically manipulated. Because many of the functionally important regions of rRNA are conserved among bacteria, drug leads developed against conserved targets in the E. coli system may produce broad-spectrum anti-infectives. However, in order the develop a system to product narrow-spectrum anti-infectives, herein we disclose method and compositions for screening Pseudomonas aeruginosa 16S rRNA in E. coli cells. In certain embodiments, a plasmid comprising the 16S rRNA gene from Pseudomonas aeruginosa t mutated to replace the natural helix 9 region with the corresponding region of the E. coli rRNA, is shown to form functional ribosomes in E. coli host cells. Li other embodiments, a plasmid, comprising the unmutated 16S rRNA from Pseudomonas aeruginosa, along with a plasmid containing the Pseudomonas aeruginosa S20 protein, can yield functional ribosomes in E. coli cells.
FILED Thursday, May 11, 2006
APPL NO 11/914062
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.330
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08294102 Lall
FUNDED BY
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Ravinder P. Lall (Clarksville, Maryland)
ABSTRACT This relates to a chemical biological threat detection system for enhancing the, discrimination in chemical biological threat detection in atmospheric air, low level chemical biological threat detection in air, as well as tactical determination of threat chemical biological agents' concentrations in a specific atmospheric range, at various time intervals. This uses the concept of quantitative monitoring the atmospheric air for chemical biological threats, as well as measuring the quantitative correlations/ratios in differential changes in the air, for the active/passive chemical biological Infrared (IR) EM radiation at an 8-12 μM wavelength, absorption/emission/scattering, using Electro-Optics. This chemical biological solution will use the reference chemical biological IR EM radiation (absorption, emission, scattering) signatures for comparison.
FILED Friday, February 17, 2012
APPL NO 13/399858
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/338.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294132 Miao et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S) Feng Miao (Mountain View, California);  Joshua Yang (Palo Alto, California);  Wei Wu (Palo Alto, California);  Shih-Yuan Wang (Palo Alto, California);  R. Stanley Williams (Portola Valley, California)
ABSTRACT A graphene memristor includes a first electrode, a second electrode electrically coupled to the first electrode, an active region interspersed between the first and second electrodes, a defective graphene structure that modulates a barrier height to migration of ions through the active region, fast diffusing ions that migrate under the influence an electric field to change a state of the graphene memristor, and a source that generates the electric field.
FILED Tuesday, March 30, 2010
APPL NO 12/750351
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08294763 Cheng et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Hui Cheng (Bridgewater, New Jersey);  Jiangjian Xiao (Plainsboro, New Jersey);  Harpreet Sawhney (West Windsor, New Jersey)
ABSTRACT A computer implemented method for deriving an attribute entity network (AEN) from video data is disclosed, comprising the steps of extracting at least two entities from the video data, tracking the trajectories of the at least two entities to form at least two tracks, deriving at least one association between at least two entities by detecting at least one event involving the at least two entities, where the detecting of at least one event is based on detecting at least one spatiotemporal motion correlation between the at least two entities, and constructing the AEN by creating a graph wherein the at least two objects form at least two nodes and the at least one association forms a link between the at least two nodes.
FILED Friday, November 14, 2008
APPL NO 12/271173
ART UNIT 2455 — Computer Networks
CURRENT CPC
Television
348/143
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 23, 2012.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2012/fedinvent-patents-20121023.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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