FedInvent™ Patents
Patent Details for Tuesday, February 12, 2013
This page was updated on Monday, March 27, 2023 at 03:44 AM GMT
Department of Defense (DOD)
| US 08371059 | Tillinghast |
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| FUNDED BY |
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| APPLICANT(S) | Ralph C. Tillinghast (Hardwick, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ralph C. Tillinghast (Hardwick, New Jersey) |
| ABSTRACT | An improved aiming post light configuration wherein a luminescent material in conjunction with an optical taper or other magnification structure is positioned within the body of the aiming post along with a recharge circuit which recharges the luminescent material periodically or when light output from the luminescent material falls below a predetermined threshold. Advantageously, the entire configuration may be integral to the aiming post itself. |
| FILED | Wednesday, June 30, 2010 |
| APPL NO | 12/826981 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/132 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371102 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jamine Lee (Burlington, Massachusetts); Neil Goldstein (Belmont, Massachusetts); Jason A. Cline (Burlington, Massachusetts); Fritz Bien (Concord, Massachusetts); Timothy C. Perkins (Billerica, Massachusetts); Brian F. Gregor (Waltham, Massachusetts) |
| ASSIGNEE(S) | Spectral Sciences, Inc. (Burlington, Massachusetts) |
| INVENTOR(S) | Jamine Lee (Burlington, Massachusetts); Neil Goldstein (Belmont, Massachusetts); Jason A. Cline (Burlington, Massachusetts); Fritz Bien (Concord, Massachusetts); Timothy C. Perkins (Billerica, Massachusetts); Brian F. Gregor (Waltham, Massachusetts) |
| ABSTRACT | A system for controlling the uniformity of combustion over a range of operating conditions in a combustor with a plurality of fuel nozzles. The system includes a number of optical sensors, each sensor comprising an optical probe that collects naturally occurring optical radiation emanating from a segment of the combustor or combustor exhaust, and at least one transducer that receives the radiation collected by the probes, compares the intensity of collected radiation from each sensor in a plurality of spectral pass-bands that are indicative of the fuel/air ratio in the combustor segments, and produces output signals that are indicative of the state of combustion in the combustor segments. A control system receives the output signals from the transducers and in response controls the fuel flow to the fuel nozzles to achieve an output from each of the sensors that has been determined to be indicative of a predetermined state of combustion. |
| FILED | Thursday, February 26, 2009 |
| APPL NO | 12/393595 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/39.281 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371134 | Rini et al. |
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| FUNDED BY |
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| APPLICANT(S) | Daniel P. Rini (Orlando, Florida); Louis Chow (Orlando, Florida); H. Randolph Anderson (Clermont, Florida); Jayanta Sankar Kapat (Oviedo, Florida); Bradley Carman (Sanford, Florida); Brian Gulliver (Orange City, Florida); Jose Mauricio Recio (Oviedo, Florida) |
| ASSIGNEE(S) | Rini Technologies, Inc. (Oviedo, Florida) |
| INVENTOR(S) | Daniel P. Rini (Orlando, Florida); Louis Chow (Orlando, Florida); H. Randolph Anderson (Clermont, Florida); Jayanta Sankar Kapat (Oviedo, Florida); Bradley Carman (Sanford, Florida); Brian Gulliver (Orange City, Florida); Jose Mauricio Recio (Oviedo, Florida) |
| ABSTRACT | The subject invention pertains to a method and apparatus for cooling. In a specific embodiment, the subject invention relates to a lightweight, compact, reliable, and efficient cooling system. The subject system can provide heat stress relief to individuals operating under, for example, hazardous conditions, or in elevated temperatures, while wearing protective clothing. The subject invention also relates to a condenser for transferring heat from a refrigerant to an external fluid in thermal contact with the condenser. The subject condenser can have a heat transfer surface and can be designed for an external fluid, such as air, to flow across the heat transfer surface and allow the transfer of heat from heat transfer surface to the external fluid. In a specific embodiment, the flow of the external fluid is parallel to the heat transfer surface. In another specific embodiment, the heat transfer surface can incorporate surface enhancements which enhance the transfer of heat from the heat transfer surface to the external fluid. In another specific embodiment, an outer layer can be positioned above the heat transfer surface to create a volume between the heat transfer surface and the outer layer through which the external fluid can flow. |
| FILED | Tuesday, June 30, 2009 |
| APPL NO | 12/495312 |
| ART UNIT | 3784 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Refrigeration 062/98 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371206 | Albrecht et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jeffrey Albrecht (Schenectady, New York); Matthew Woelfersheim (Cambridge, New York); Michael Palage (Loudonville, New York); James Papandrea (Slingerlands, New York); Mohamed Badawi (Niskayuna, New York) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey Albrecht (Schenectady, New York); Matthew Woelfersheim (Cambridge, New York); Michael Palage (Loudonville, New York); James Papandrea (Slingerlands, New York); Mohamed Badawi (Niskayuna, New York) |
| ABSTRACT | A gun with a wedge-type breechblock containing a single make-break junction assembly, located between the stationary mass of the cradle and the breechblock. The make-break junction assembly having a first set of contacts located along the bottom of the ramp structure affixed to the cradle and a second set of contacts housed in a shoe affixed to the bottom of the breechblock, at a location corresponding to the first set of contacts. Such that, when the breechblock is in-battery and the gun loaded, this shoe will be aligned with and adjacent to the first set of contacts, so that the make-break circuit will be completed. |
| FILED | Tuesday, March 30, 2010 |
| APPL NO | 12/749700 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/28.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371224 | Boswell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Christopher Boswell (Alexandria, Virginia); Gerardo Pangilinan (Alexandria, Virginia); Von Whitley (Los Alamos, New Mexico) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Boswell (Alexandria, Virginia); Gerardo Pangilinan (Alexandria, Virginia); Von Whitley (Los Alamos, New Mexico) |
| ABSTRACT | An apparatus and method for selectively varying the yield of an explosive device is provided. The apparatus generally comprises a main charge that may selectively be consumed and/or detonated to achieve the selected yield ranging from about 0% to about 100%. |
| FILED | Wednesday, November 26, 2008 |
| APPL NO | 12/315489 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/475 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371705 | Hoffman |
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| FUNDED BY |
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| APPLICANT(S) | Robert Clinton Hoffman (Woodstock, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert Clinton Hoffman (Woodstock, Virginia) |
| ABSTRACT | A mirror having a first substrate and a reflective film formed on the first substrate, the reflective film made of mercury and at least one metal, wherein the mirror is operative such that light incident upon the first substrate and having an intensity that falls below a fluence threshold is reflected by the reflective film, and light incident upon the first substrate and having an intensity that exceeds the fluence threshold passes through the reflective film. |
| FILED | Tuesday, March 11, 2008 |
| APPL NO | 12/046228 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/839 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371812 | Manteiga et al. |
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| FUNDED BY |
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| APPLICANT(S) | John Alan Manteiga (North Andover, Massachusetts); Robert John Parks (Ipswich, Massachusetts); Wilhelm Hernandez (Lynn, Massachusetts); Patrick Murphy (Kensington, New Hampshire) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | John Alan Manteiga (North Andover, Massachusetts); Robert John Parks (Ipswich, Massachusetts); Wilhelm Hernandez (Lynn, Massachusetts); Patrick Murphy (Kensington, New Hampshire) |
| ABSTRACT | A turbine frame assembly for a gas turbine engine includes: (a) a turbine frame including: (i) an outer ring; (ii) a hub; (ii) a plurality of struts extending between the hub and the outer ring; (b) a two-piece strut fairing surrounding each of the struts, including: (i) an inner band; (ii) an outer band; and (iii) an airfoil-shaped vane extending between the inner and outer bands; (d) a plurality of nozzle segments disposed between the outer ring and the hub, each nozzle segment being an integral metallic casting including: (i) an arcuate outer band; (ii) an arcuate inner band; and (ii) an airfoil-shaped vane. |
| FILED | Saturday, November 29, 2008 |
| APPL NO | 12/325174 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/209.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372183 | Doucette et al. |
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| FUNDED BY |
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| APPLICANT(S) | Luke D. Doucette (Hampden, Maine); Carl P. Tripp (Orono, Maine); Brian J. Ninness (Hampden, Maine) |
| ASSIGNEE(S) | Orono Spectral Solution, Inc. (Orono, Maine); University of Maine System Board of Trustees (Bangor, Maine) |
| INVENTOR(S) | Luke D. Doucette (Hampden, Maine); Carl P. Tripp (Orono, Maine); Brian J. Ninness (Hampden, Maine) |
| ABSTRACT | This invention relates to a detection system for particles suspended in a gas. The detection system includes an electrostatic precipitator constructed to collect the particles from the gas onto a collection surface using the force of an induced electrostatic charge on the particles. The detection system also includes an optical probe coupled with the electrostatic precipitator and constructed to probe the particles with a beam in order to detect the particles. The body of the electrostatic precipitator has a geometry that allows the beam to travel from the optical probe to the collection surface. |
| FILED | Tuesday, June 12, 2007 |
| APPL NO | 11/811833 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation: Apparatus 096/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372197 | Svensson |
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| FUNDED BY |
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| APPLICANT(S) | Stefan P. Svensson (Columbia, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Stefan P. Svensson (Columbia, Maryland) |
| ABSTRACT | A control system and method for controlling temperatures while performing a MBE deposition process, wherein the control system comprises a MBE growth structure; a heater adapted to provide heat for the MBE deposition process on the MBE growth structure; and a control computer adapted to receive a plurality of dynamic feedback control signals derived from the MBE growth structure; switch among a plurality of control modes corresponding with the plurality of dynamic feedback control signals; and send an output power signal to the heater to control the heating for the MBE deposition process based on a combination of the plurality of control modes. In one embodiment, the plurality of dynamic feedback control signals comprises thermocouple signals and pyrometer signals. |
| FILED | Monday, August 29, 2011 |
| APPL NO | 13/219762 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372315 | Beaujuge et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pierre Marc Beaujuge (Jeddah, Saudi Arabia); John R. Reynolds (Gainesville, Florida); Stefan Martin Ellinger (Visp, Switzerland) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Pierre Marc Beaujuge (Jeddah, Saudi Arabia); John R. Reynolds (Gainesville, Florida); Stefan Martin Ellinger (Visp, Switzerland) |
| ABSTRACT | A donor-acceptor (DA) π-conjugated polymer with high charge transfer mobility has a plurality of D1kAD1k portions, where k is 1 or 2, D1 is a donor unit having at least one solubilizing side chain, and A is an acceptor unit, and the donor-acceptor (DA) π-conjugated polymer has a plurality of D2m spacer sequences situated between the D1kAD1k portions, where m is 1 to 6 and D2 is a second donor unit where all atoms of the unit are coplanar in at least one conformation that the unit can assume. The DA π-conjugated polymer can reflect a blue tinted green, deep green, or yellow tinted green color. The DA π-conjugated polymers have space-charge limited (SCL) zero field hole mobilities of at least 1×10−6 cm2V−1s−1. |
| FILED | Wednesday, May 26, 2010 |
| APPL NO | 13/321880 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/586 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372384 | Chisholm et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bret Ja Chisholm (West Fargo, North Dakota); Partha Majumdar (Fargo, North Dakota); Shane J. Stafslien (West Fargo, North Dakota); Philip Boudjouk (Fargo, North Dakota) |
| ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
| INVENTOR(S) | Bret Ja Chisholm (West Fargo, North Dakota); Partha Majumdar (Fargo, North Dakota); Shane J. Stafslien (West Fargo, North Dakota); Philip Boudjouk (Fargo, North Dakota) |
| ABSTRACT | Functionalized cross-linked polysiloxanes, such as quaternary ammonium terminated cross-linked polyalkylsiloxanes are described herein. The functionalized cross-linked polysiloxanes may be used in an antifouling composition to prevent biological fouling in aqueous and/or marine environments. |
| FILED | Monday, January 07, 2008 |
| APPL NO | 12/006926 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.90 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372578 | Christophersen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Marc Christophersen (Alexandria, Virginia); Bernard Phlips (Great Falls, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marc Christophersen (Alexandria, Virginia); Bernard Phlips (Great Falls, Virginia) |
| ABSTRACT | A method of: directing an exposing light through an optical diffuser; directing the diffused light though a photomask having transparent areas corresponding to a gray-tone pattern; directing the masked light onto a photoresist material on a substrate; developing the photoresist to produce a three dimensional structure in the photoresist. |
| FILED | Thursday, August 21, 2008 |
| APPL NO | 12/195594 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372697 | Khan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Asif Khan (Irmo, South Carolina); Vinod Adivarahan (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Asif Khan (Irmo, South Carolina); Vinod Adivarahan (Columbia, South Carolina) |
| ABSTRACT | Novel silicon dioxide and silicon nitride deposition methods are generally disclosed. In one embodiment, the method includes depositing silicon on the surface of a substrate having a temperature of between about 65° C. and about 350° C. The heated substrate is exposed to a silicon source that is substantially free from an oxidizing agent. The silicon on the surface is then oxidized with an oxygen source that is substantially free from a silicon source. As a result of oxidizing the silicon, a silicon oxide layer forms on the surface of the substrate. Alternatively, or in additionally, a nitrogen source can be provided to produce silicon nitride on the surface of the substrate. |
| FILED | Monday, May 07, 2007 |
| APPL NO | 11/800712 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/141 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372908 | Guo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Zhanhu Guo (Beaumont, Texas); H. Thomas Hahn (Malibu, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhanhu Guo (Beaumont, Texas); H. Thomas Hahn (Malibu, California) |
| ABSTRACT | An improved method is provided to prepare reinforced resin nanocomposites without the need of surfactants or coupling agents. The present invention comprises the use of monomers for improving the dispersion of nano-sized materials and enhancing the particle/matrix interaction. One comprises mixing a plurality of nanoparticles with a monomer resin to form a mixture, blending a catalyst and a promoter with the mixture, and curing the blended mixture to form a polymerized nanocomposite. The monomers, which serve to stabilize the nanoparticles, are covalently bound onto the nanoparticle surface and copolymerize with non-bound monomers after introduction of a catalyst and a promoter that initiate polymerization. Without any additional surfactant or coupling agent, the resin is chemically bound onto the nanoparticle surface and protects the iron nanoparticles from agglomeration and oxidation. |
| FILED | Friday, May 15, 2009 |
| APPL NO | 12/467196 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 524/431 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372926 | Palmese et al. |
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| FUNDED BY |
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| APPLICANT(S) | Guiseppe Raffaello Palmese (Hainesport, New Jersey); John Joseph LaScala (Bel Air, Maryland); James Matthew Sands (Kingsville, Maryland) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Guiseppe Raffaello Palmese (Hainesport, New Jersey); John Joseph LaScala (Bel Air, Maryland); James Matthew Sands (Kingsville, Maryland) |
| ABSTRACT | Novel fatty acid monomers and methods for their synthesis are provided for use in polymerization reactions. Fatty acid monomers are employed as reactive diluents in the polymerization of vinyl esters and polyesters for one or more purposes selected from improving the fracture resistance, lowering the processing viscosity and reducing the volatile organic compounds present in the polymerization mixture. |
| FILED | Friday, August 08, 2008 |
| APPL NO | 12/188326 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 526/161 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372928 | Gleason et al. |
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| FUNDED BY |
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| APPLICANT(S) | Karen K. Gleason (Lexington, Massachusetts); Jingjing Xu (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Karen K. Gleason (Lexington, Massachusetts); Jingjing Xu (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed is a substantially alternating copolymer that is conformal, hard, flexible, and has low oxygen permeability. Also disclosed is an iCVD-based method of coating a substrate with the substantially alternating copolymer. |
| FILED | Friday, May 20, 2011 |
| APPL NO | 13/112489 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 526/271 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372949 | Belcher |
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| FUNDED BY |
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| APPLICANT(S) | Angela M. Belcher (Lexington, Massachusetts) |
| ASSIGNEE(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Angela M. Belcher (Lexington, Massachusetts) |
| ABSTRACT | The present invention includes methods for selective binding of inorganic materials and the compositions that made up of the selecting agent and the target materials. One form of the present invention is a method for selecting crystal-binding peptides with binding specificity including the steps of contacting one or more amino acid oligomers with one or more single-crystals of a semiconductor material so that the oligomers may bind to the crystal and eluting the bound amino acid oligomers from the single-crystals. |
| FILED | Tuesday, July 24, 2007 |
| APPL NO | 11/782038 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373107 | Meyers et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ronald Everett Meyers (Columbia, Maryland); Keith Scott Deacon (Coumbia, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ronald Everett Meyers (Columbia, Maryland); Keith Scott Deacon (Coumbia, Maryland) |
| ABSTRACT | A system for imaging information comprising a spatial receiver, a chaotic photon light source comprising a first beam directed at a first predetermined area containing an object, and a second beam received by the spatial receiver and measured at specific intervals in time; the spatial receiver transmitting spatial information correlated to specific intervals of time to a processor; and a first receiver detecting the influence of the object on the first light beam; the first receiver not being in the line of sight with the first predetermined area and adapted to detect light from a second predetermined area spaced from the first predetermined area, the at least one processor operating to correlate the outputs of the first receiver with spatial information derived from the spatial receiver at correlating intervals of time to create an image of the object and a method for practicing the invention. |
| FILED | Thursday, August 04, 2011 |
| APPL NO | 13/198133 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/208.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373127 | Ragucci et al. |
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| FUNDED BY |
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| APPLICANT(S) | Anthony J. Ragucci (Bryan, Texas); John Lusher (Bryan, Texas) |
| ASSIGNEE(S) | Lynntech, Inc. (College Station, Texas) |
| INVENTOR(S) | Anthony J. Ragucci (Bryan, Texas); John Lusher (Bryan, Texas) |
| ABSTRACT | A system and method are used to search for a thermal target from a moving aerial platform. The system includes a computer corrected to a wide field-of-view thermal imager, a narrow field-of-view thermal imager, a global navigation satellite system receiver, and an inertial navigation system. The wide field-of-view thermal imager acouires multiple images as the wide field-of-view thermal imager moves relative to a search area. Each point of each imaoe is correlated to a stationary position within the search area. The computer is configured to independently time-average the thermal signal amplitude emanating from each stationary sector in the search area imaged bv the wide field-of-view thermal imager. and direct the narrow field-of-view thermal imager to point to the stationary position of the sector of interest and display a thermal imaoe associated with the sector of interest to a user. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/491720 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/346 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373141 | Shields et al. |
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| FUNDED BY |
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| APPLICANT(S) | Garry E. Shields (Ashburn, Virginia); Paul W. Brown (Columbia, Maryland); Gordon K. Riel (Edgewater, Maryland); Robert D. Rogalski (Annapolis, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Garry E. Shields (Ashburn, Virginia); Paul W. Brown (Columbia, Maryland); Gordon K. Riel (Edgewater, Maryland); Robert D. Rogalski (Annapolis, Maryland) |
| ABSTRACT | Dosimeter chips are widely distributed over a territorial area. This is followed by photographing the area from above to produce a color photograph. The color photograph is compared with radiation/color calibration data for the dosimeter chips. The total radiation accumulation is determined from the calibration data. The invention is for emergency use after civil accidents, for ascertaining a threat to military personnel before entering the battlefield or for interrogating a ship at sea. |
| FILED | Monday, September 28, 2009 |
| APPL NO | 12/567814 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/473.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373144 | McCord et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mark A. McCord (Los Gatos, California); Paul F. Petric (Pleasanton, California); Allen Carroll (San Jose, California) |
| ASSIGNEE(S) | KLA-Tencor Corporation (Milpitas, California) |
| INVENTOR(S) | Mark A. McCord (Los Gatos, California); Paul F. Petric (Pleasanton, California); Allen Carroll (San Jose, California) |
| ABSTRACT | One embodiment relates to an electron-beam apparatus for writing a pattern on a target substrate. The apparatus includes a plurality of arrays of actively-controlled pixel elements at a surface of a reflective electron patterning device. The plurality of arrays of actively-controlled pixel elements are arranged so that there is an area without any actively-controlled pixel elements in a region surrounding an optical axis of the objective lens. The plurality of arrays may be arranged to each lie on a circle centered on the optical axis. Other features, aspects and embodiments are also disclosed. |
| FILED | Tuesday, August 31, 2010 |
| APPL NO | 12/873158 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/492.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373458 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kanon Liu (Arcadia, California); Bryan W. Kean (Fairfax, Virginia); James F. Asbrock (Oceanside, California) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Kanon Liu (Arcadia, California); Bryan W. Kean (Fairfax, Virginia); James F. Asbrock (Oceanside, California) |
| ABSTRACT | According to one embodiment, a circuit comprises a Capacitive Trans-Impedance Amplifier (CTIA) configured to receive a current pulse at an input and convert the current pulse to a voltage step. The voltage step is directed to a first signal path and a second signal path. When the voltage step exceeds a first threshold, the first signal path directs an enable pulse to the second signal path. The second signal path generates an output pulse when the voltage step exceeds a second threshold and the enable pulse is enabled. The second signal path comprises a first, a second, and a third amplifier to increase detection of the voltage step by the second signal path. |
| FILED | Tuesday, November 17, 2009 |
| APPL NO | 12/619870 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373608 | Drexler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jerome P. Drexler (Wyoming, Minnesota); Robert C. Becker (Eden Prairie, Minnesota); David W. Meyers (Brooklyn Park, Minnesota); Kelly P. Muldoon (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Jerome P. Drexler (Wyoming, Minnesota); Robert C. Becker (Eden Prairie, Minnesota); David W. Meyers (Brooklyn Park, Minnesota); Kelly P. Muldoon (Minneapolis, Minnesota) |
| ABSTRACT | A method of verifying programmable antenna configurations is disclosed. The method comprises selecting a desired antenna configuration from a plurality of antenna configuration patterns, with the selected antenna configuration forming at least one reconfigurable antenna from reconfigurable antenna array elements. The method validates the formation of the selected antenna configuration to determine antenna performance of the at least one reconfigurable antenna. |
| FILED | Wednesday, December 05, 2007 |
| APPL NO | 11/951023 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/757 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373609 | Dorsey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | W Mark Dorsey (Elkridge, Maryland); Amir I Zaghloul (Bethesda, Maryland); Mark G Parent (Port Tobacco, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia); Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | W Mark Dorsey (Elkridge, Maryland); Amir I Zaghloul (Bethesda, Maryland); Mark G Parent (Port Tobacco, Maryland) |
| ABSTRACT | A reconfigurable polarization antenna includes a microwave dielectric substrate having a ground plane that has a centrally located slot with five conducting patches, four of which form an evenly spaced apart perimeter group with a gap between each and the fifth, centrally positioned conducting patch. A conducting pad is positioned in each gap and is connected via a switch to the ground plane. A microstrip feed line including a short stub is positioned on the opposite side of the substrate and electromagnetically coupled to the slot. The polarization of the antenna is reconfigured by a selection of an on or off state of each of said switches. |
| FILED | Tuesday, June 09, 2009 |
| APPL NO | 12/481025 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/769 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373627 | Veitch |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Randall C. Veitch (Nazareth, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Randall C. Veitch (Nazareth, Pennsylvania) |
| ABSTRACT | A driver circuit for driving a light emitting semiconductor device. The driver circuit of this invention includes a capacitor connected between a source of voltage pulses and a light emitting semiconductor device. |
| FILED | Friday, July 30, 2004 |
| APPL NO | 10/909180 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/82 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373862 | Mullen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Linda J. Mullen (Chesapeake Beach, Maryland); Alan Laux (Great Mills, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Linda J. Mullen (Chesapeake Beach, Maryland); Alan Laux (Great Mills, Maryland) |
| ABSTRACT | An extended range optical imaging system and method for use in turbid media generates a beam of coherent light, modulates the beam of coherent light to encode scan information, directs the modulated beam of coherent light from a first location through the turbid medium toward a target, scans the modulated beam of coherent light over the target in a pattern, according to the scan information, to illuminate the target and to cause light to be reflected, detects the modulated light reflected from the target with a sensor at a second location in the turbid medium to derive an output signal that varies in proportion to the modulated reflected light, demodulates the output signal to derive information comprising the scan information, and constructs an image from the output signal and the scan information so derived. |
| FILED | Wednesday, June 02, 2010 |
| APPL NO | 12/792183 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373999 | Eifert |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel J. Eifert (Oviedo, Florida) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Daniel J. Eifert (Oviedo, Florida) |
| ABSTRACT | A standoff device and a concomitant method of attaching the same to a printed wiring board, comprising inserting into an opening in the printed wiring board a standoff device comprising a threaded body, a neck region narrower and atop the body, and a hexagonal head atop the neck and comprising one or more anti-turn features, and threading a nut onto the body to contact a side of the printed wiring board opposite that contacted by the hexagonal head. |
| FILED | Friday, July 25, 2008 |
| APPL NO | 12/180291 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/804 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374048 | Apalkov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dmytro Apalkov (San Jose, California) |
| ASSIGNEE(S) | Grandis, Inc. (San Jose, California) |
| INVENTOR(S) | Dmytro Apalkov (San Jose, California) |
| ABSTRACT | A method and system for providing a magnetic junction usable in a magnetic device are described. The magnetic junction includes a pinned layer, a nonmagnetic spacer layer, and a free layer. The nonmagnetic spacer layer is between the pinned layer and the free layer. The free layer has a magnetic anisotropy, at least a portion of which is a biaxial anisotropy. The magnetic junction is configured such that the free layer is switchable between a plurality of stable magnetic states when a write current is passed through the magnetic junction. |
| FILED | Wednesday, August 11, 2010 |
| APPL NO | 12/854628 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/225.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374054 | Rikoski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard J. Rikoski (Alameda, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Richard J. Rikoski (Alameda, California) |
| ABSTRACT | An apparatus and method for relating echoes from a surface or object produced by irradiation, such as by sonar or radar, from different grazing angles according to the relationship: |
| FILED | Monday, May 17, 2010 |
| APPL NO | 12/802454 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374055 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tsih C Yang (Great Falls, Virginia); Altan Turgut (Fairfax, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Tsih C Yang (Great Falls, Virginia); Altan Turgut (Fairfax, Virginia) |
| ABSTRACT | A system and method are described for locating and communicating with miners in an underground mine, in which miners carry a battery-powered signal unit with an impact actuator engagable with a wall, floor, or ceiling surface of the mine to transmit acoustic signals through the ground, and actuate controls on the unit to send a predefined message or a specific message via the impact actuator to ground-coupled acoustic receivers coupled with a base station that includes a decoder to determine the message sent by the miner and a location component to determine the miner's location based on the received signals. |
| FILED | Friday, June 19, 2009 |
| APPL NO | 12/487884 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374311 | Kenton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marc Kenton (Hanover, New Hampshire); John Wilson (Lebanon, New Hampshire); Matthew Miller (Hanover, New Hampshire); Christopher Eaton (Vershire, Vermont); Nabil Elkouh (Enfield, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marc Kenton (Hanover, New Hampshire); John Wilson (Lebanon, New Hampshire); Matthew Miller (Hanover, New Hampshire); Christopher Eaton (Vershire, Vermont); Nabil Elkouh (Enfield, New Hampshire) |
| ABSTRACT | A method of determining whether a stack of components in a device are in a desired order includes irradiating each of the components in the device with an energy beam. The radiation emissions from each of the irradiated components are detected with a radiation detector. The detected radiation emissions are analyzed using a central processing unit (CPU) to determine whether the components in the device are stacked in the desired order. |
| FILED | Tuesday, April 06, 2010 |
| APPL NO | 12/755177 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374386 | Bayram et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sevinc Bayram (Brooklyn, New York); Husrev Taha Sencar (Lyndhurst, New Jersey); Nasir Memon (Holmdel, New Jersey) |
| ASSIGNEE(S) | Polytechnic Institute of New York University (Brooklyn, New York) |
| INVENTOR(S) | Sevinc Bayram (Brooklyn, New York); Husrev Taha Sencar (Lyndhurst, New Jersey); Nasir Memon (Holmdel, New Jersey) |
| ABSTRACT | Several promising techniques have been recently proposed to bind an image or video to its source acquisition device. These techniques have been intensively studied to address performance issues, but the computational efficiency aspect has not been given due consideration. Considering very large databases, the efficiency of the sensor fingerprint based source device identification technique is described. Novel schemes that improve search complexity as compared to a conventional approach are described. |
| FILED | Thursday, January 27, 2011 |
| APPL NO | 13/015451 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374468 | Jiang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shibin Jiang (Tucson, Arizona) |
| ASSIGNEE(S) | AdValue Photonics, Inc. (Tucson, Arizona) |
| INVENTOR(S) | Shibin Jiang (Tucson, Arizona) |
| ABSTRACT | An all-fiber Faraday rotator array comprising a plurality of Faraday rotating fibers, each having a doping concentration of 55%-85% (wt./wt.) of a rare-earth oxide, and a magnetic tube surrounding the plurality of Faraday rotating fibers is presented. The rare-earth oxide is selected from the group comprising: Pr2O3, Nd2O3, Pm2O3, Sm2O3, Eu2O3, Gd2O3, Tb2O3, Dy2O3, Ho2O3; Er2O3, Tm2O3, Yb2O3, La2O3, Ga2O3, Ce2O3, and Lu2O3. Additionally, an all-fiber isolator using highly rare-earth oxide doped fibers is disclosed. |
| FILED | Wednesday, May 12, 2010 |
| APPL NO | 12/778712 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374765 | Rubin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stuart H. Rubin (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stuart H. Rubin (San Diego, California) |
| ABSTRACT | A method includes selecting, from a data table containing a plurality of weighted independent variable columns and rows, where each of the columns represents an independent input variable feature and each row represents a set of stored independent input variables and a corresponding stored dependent variable, a row that best matches received sensor independent input variable data from at least one vehicle sensor, causing a vehicle accelerator to gradually accelerate a vehicle to a vehicle acceleration level corresponding to the stored dependent variable of the selected best match row, and modifying a weight of the weighted independent variable columns based upon received user feedback to the vehicle acceleration level. The weights may then be normalized and the received sensor independent input variable data may be stored within a new row of the data table if the weight modification produces a net overall improvement in the data table dependency mapping. |
| FILED | Tuesday, November 23, 2010 |
| APPL NO | 12/952719 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08375032 | Birdwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | J. Douglas Birdwell (Oak Ridge, Tennessee); Tse-Wei Wang (Oak Ridge, Tennessee); David J. Icove (Knoxville, Tennessee); Sally P. Horn (Knoxville, Tennessee); Mark S. Rader (Huntsville, Alabama) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | J. Douglas Birdwell (Oak Ridge, Tennessee); Tse-Wei Wang (Oak Ridge, Tennessee); David J. Icove (Knoxville, Tennessee); Sally P. Horn (Knoxville, Tennessee); Mark S. Rader (Huntsville, Alabama) |
| ABSTRACT | Method and apparatus for predicting properties of a target object, in particular, one of an origin and a source, comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, a fire event and residual objects may be located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages. |
| FILED | Friday, June 25, 2010 |
| APPL NO | 12/823320 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/737 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 08372046 | Meng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ellis Meng (Pasadena, California); Ronalee Lo Mann (Somerville, Massachusetts) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Ellis Meng (Pasadena, California); Ronalee Lo Mann (Somerville, Massachusetts) |
| ABSTRACT | A drug delivery device may include a drug reservoir configured to contain and controllably deliver a fluidic drug. A tube may be configured to deliver the fluid from the drug reservoir through a lumen in the tube to another location. A valve wholly within the lumen of the tube may regulate the flow of the fluid through the tube without substantially diverting the direction in which the fluid flows through the tube. The valve may contain only a single member which moves during operation of the valve. The valve may be configured to regulate the flow of fluid in a bandpass manner by allowing fluid to flow through the valve only when the pressure of the fluid is above a minimum and below a maximum. The valve may be held in place within the tube solely by frictional force between the valve and a wall of the tube. |
| FILED | Friday, February 19, 2010 |
| APPL NO | 12/709188 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/246 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372358 | Groisman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Groisman (San Diego, California); Edgar Gutierrez (San Diego, California); Eugene Tkachenko (San Diego, California); Mark H. Ginsberg (San Diego, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander Groisman (San Diego, California); Edgar Gutierrez (San Diego, California); Eugene Tkachenko (San Diego, California); Mark H. Ginsberg (San Diego, California) |
| ABSTRACT | In a microfluidic system, a magnetic clamp for sealing a flexible microchannel chip includes a base formed from a magnetically-attractable material. The base supports a window for viewing the face of the microfluidic chip. A ring with magnets uniformly distributed around it is disposed over the base. A transparent disk attached to the top of the ring has an inlet and an outlet for introducing and removing a fluid medium into a cavity defined the disk, the window, the center opening of the ring and the base. An elastomer cushion is attached to the inner surface of the disk. The magnetic force between the base and the magnets on the ring compresses the cushion against the microfluidic chip so that the microchannels are sealed against the window with a uniform and reproducible pressure. |
| FILED | Monday, August 23, 2010 |
| APPL NO | 12/861686 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372390 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pin Wang (Pasadena, California); Lili Yang (Pasadena, California); David Baltimore (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Pin Wang (Pasadena, California); Lili Yang (Pasadena, California); David Baltimore (Pasadena, California) |
| ABSTRACT | Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers. |
| FILED | Friday, January 15, 2010 |
| APPL NO | 12/688779 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372582 | Geraldes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pedro Geraldes (Brookline, Massachusetts); George Liang King (Dover, Massachusetts) |
| ASSIGNEE(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Pedro Geraldes (Brookline, Massachusetts); George Liang King (Dover, Massachusetts) |
| ABSTRACT | Described are methods of identifying modulators of metabolic memory, for the treatment of microvascular complications of diabetes, as well as methods of use thereof. Also described are methods of treating microvascular complications of diabetes by decreasing expression and/or activity of SHP-1. |
| FILED | Wednesday, August 01, 2007 |
| APPL NO | 12/375901 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372586 | Croce |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carlo M. Croce (Columbus, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Carlo M. Croce (Columbus, Ohio) |
| ABSTRACT | Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins. |
| FILED | Monday, October 17, 2011 |
| APPL NO | 13/274730 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372593 | Orser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cindy S. Orser (Lafayette, Colorado); Tao Pan (Gaithersburg, Maryland); Jasmeet Sethi (Germantown, Maryland) |
| ASSIGNEE(S) | Adlyfe, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Cindy S. Orser (Lafayette, Colorado); Tao Pan (Gaithersburg, Maryland); Jasmeet Sethi (Germantown, Maryland) |
| ABSTRACT | The invention provides methods and kits for detecting conformationally altered proteins, such as prions or other proteins associated with disease states, in a sample. The methods comprise selectively capturing and separating complexes of peptide and conformationally altered protein from substances that interfere with detection of such complexes, and preferably amplification of the detection signal b addition of a second double-labeled peptide. |
| FILED | Tuesday, February 14, 2006 |
| APPL NO | 11/884316 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372600 | Sachs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederick Sachs (Eden, New York); Zonglu Hua (Williamsville, New York); Stephen Besch (Buffalo, New York); Harsh Deep Chopra (Williamsville, New York); Philip Gottlieb (Buffalo, New York) |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
| INVENTOR(S) | Frederick Sachs (Eden, New York); Zonglu Hua (Williamsville, New York); Stephen Besch (Buffalo, New York); Harsh Deep Chopra (Williamsville, New York); Philip Gottlieb (Buffalo, New York) |
| ABSTRACT | A method and apparatus for measuring changes in cell volume generally includes introducing cells into a chamber having a volume between 2 and 100 times the volume of the introduced cell. A first electrically conductive extracellular fluid is introduced into the chamber and a current is applied. The voltage induced by said current flow is measured. The first fluid is exchanged with a second electrically conductive extracellular fluid and a current is applied. The voltage induced by said current flow is measured. The first induced voltage result and the second induced voltage result are used in conjunction with known voltages induced by such current flows to monitor changes in the volume corresponding to fluid flow between the cell and an extracellular fluid. |
| FILED | Wednesday, February 25, 2009 |
| APPL NO | 12/380232 |
| ART UNIT | 1775 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/39 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372601 | Metcalf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William W. Metcalf (Savoy, Illinois); Wilfred A. van der Donk (Champaign, Illinois); Junkal Zhang (Urbana, Illinois); Benjamin T. Circello (Maineville, Ohio); Svetlana A. Borisova (Champaign, Illinois) |
| ASSIGNEE(S) | University of Illinois at Urbana-Champaign (Urbana, Illinois) |
| INVENTOR(S) | William W. Metcalf (Savoy, Illinois); Wilfred A. van der Donk (Champaign, Illinois); Junkal Zhang (Urbana, Illinois); Benjamin T. Circello (Maineville, Ohio); Svetlana A. Borisova (Champaign, Illinois) |
| ABSTRACT | The disclosure of the present application provides polypeptide sequences and nucleotide sequences coding for the polypeptide sequences of proteins used in the production of APPA-containing peptides. In at least one embodiment of the present disclosure, an isolated nucleic acid is disclosed which comprises a nucleotide sequence encoding a polypeptide having a sequence identity of 60 percent or greater to an amino acid sequence selected from the group consisting of SEQ ID NOS: 2-13, and 15-23. |
| FILED | Friday, January 21, 2011 |
| APPL NO | 13/011075 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/41 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372621 | Frost |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John W. Frost (Okemos, Michigan) |
| ASSIGNEE(S) | Board of Trustees Operating Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | John W. Frost (Okemos, Michigan) |
| ABSTRACT | Novel enzymes and novel enzymatic pathways for the pyruvate-based synthesis of shikimate or at least one intermediate thereto or derivative thereof, nucleic acids encoding the enzymes, cells transformed therewith, and kits containing said enzymes, cells, or nucleic acid. A KDPGal aldolase is used to perform condensation of pyruvate with D-erythrose 4-phosphate to form 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP); a 3-dehydroquinate synthase is used to convert the DAHP to 3-dehydroquinate (DHQ); DHQ dehydratase can then convert DHQ to the key shikimate intermediate, 3-dehydroshikimate. |
| FILED | Tuesday, July 20, 2010 |
| APPL NO | 12/839964 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/232 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372636 | Wittrup et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | K. Dane Wittrup (Chestnut Hill, Massachusetts); David M. Kranz (Champaign, Illinois); Michele Kieke (Urbana, Illinois); Eric T. Boder (Media, Pennsylvania) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | K. Dane Wittrup (Chestnut Hill, Massachusetts); David M. Kranz (Champaign, Illinois); Michele Kieke (Urbana, Illinois); Eric T. Boder (Media, Pennsylvania) |
| ABSTRACT | The present invention provides a genetic method for tethering polypeptides to the yeast cell wall in a form accessible for binding to macromolecules. Combining this method with fluorescence-activated cell sorting provides a means of selecting proteins with increased or decreased affinity for another molecule, altered specificity, or conditional binding. Also provided is a method for genetic fusion of the N terminus of a polypeptide of interest to the C-terminus of the yeast Aga2p cell wall protein. The outer wall of each yeast cell can display approximately 104 protein agglutinins. The native agglutinins serve as specific adhesion contacts to fuse yeast cells of opposite mating type during mating. In effect, yeast has evolved a platform for protein-protein binding without steric hindrance from cell wall components. As one embodiment, attaching an scFv antibody fragment to the Aga2p agglutinin effectively mimics the cell surface display of antibodies by B cells in the immune system for affinity maturation in vivo. As another embodiment, T cell receptor mutants can be isolated by this method that are efficiently displayed on the yeast cell surface, providing a means of altering T cell receptor binding affinity and specificity by library screening. |
| FILED | Tuesday, December 16, 2008 |
| APPL NO | 12/316916 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372640 | Zanetti |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Maurizio Zanetti (La Jolla, California) |
| ASSIGNEE(S) | Nevagen LLC (La Jolla, California) |
| INVENTOR(S) | Maurizio Zanetti (La Jolla, California) |
| ABSTRACT | The invention provides a method for stimulating an immune response by administering to a lymphoid tissue a nucleic acid molecule comprising an expression element operationally linked to a nucleic acid sequence encoding one or more heterologous epitopes. The heterologous epitope can be inserted into a complementarity-determining region of an immunoglobulin molecule. The invention also provides a nucleic acid molecule comprising a hematopoietic expression element operationally linked to a nucleic acid sequence encoding a heterologous polypeptide. The invention additionally provides a method of treating a condition by administering a nucleic acid molecule comprising a hematopoietic cell expression element operationally linked to a nucleic acid sequence encoding a heterologous polypeptide, wherein the nucleic acid molecule is targeted to a hematopoietic cell. |
| FILED | Monday, December 18, 2006 |
| APPL NO | 11/640778 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372801 | Roosild et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tarmo Roosild (Las Vegas, Nevada); Jason Greenwald (Zurich, Switzerland); Senyon Choe (Solana Beach, California) |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Tarmo Roosild (Las Vegas, Nevada); Jason Greenwald (Zurich, Switzerland); Senyon Choe (Solana Beach, California) |
| ABSTRACT | A class of integral membrane proteins, referred to as Mistic polypeptides, their variants, fusion proteins including a Mistic polypeptide domain, and nucleic acid molecules encoding Mistic polypeptides and Mistic fusion proteins are disclosed herein. Also described are methods of using Mistic polypeptides and Mistic fusion proteins to produce and/or isolate recombinant proteins (including without limitation classes of eukaryotic proteins that have previously been intractable to recombinant bacterial expression, such as, eukaryotic integral membrane proteins). |
| FILED | Thursday, August 13, 2009 |
| APPL NO | 12/540852 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372808 | Messing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albee Messing (Madison, Wisconsin); Woosung Cho (Madison, Wisconsin); Jon Scott Thorson (Middleton, Wisconsin); Randal D. Goff (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Albee Messing (Madison, Wisconsin); Woosung Cho (Madison, Wisconsin); Jon Scott Thorson (Middleton, Wisconsin); Randal D. Goff (Madison, Wisconsin) |
| ABSTRACT | Provided herein are methods of decreasing glial fibrillary acidic protein (GFAP) levels in a cell. Such methods include administering an effective amount of a GFAP lowering compound to the cell. Also provided are compounds useful for the treatment of Alexander disease in subjects at risk of or diagnosed with Alexander disease and methods for the identification of such compounds. |
| FILED | Monday, October 26, 2009 |
| APPL NO | 12/589638 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372813 | Aggen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Bradley Aggen (Burlingame, California); Martin Sheringham Linsell (San Mateo, California); Adam Aaron Goldblum (Berkeley, California); Darin James Hildebrandt (Mountain View, California); Timothy Robert Kane (Moss Beach, California); Paola Dozzo (San Francisco, California); Micah James Gliedt (Sunnyvale, California); Heinz Ernst Moser (San Mateo, California) |
| ASSIGNEE(S) | Achaogen, Inc. (South San Francisco, California) |
| INVENTOR(S) | James Bradley Aggen (Burlingame, California); Martin Sheringham Linsell (San Mateo, California); Adam Aaron Goldblum (Berkeley, California); Darin James Hildebrandt (Mountain View, California); Timothy Robert Kane (Moss Beach, California); Paola Dozzo (San Francisco, California); Micah James Gliedt (Sunnyvale, California); Heinz Ernst Moser (San Mateo, California) |
| ABSTRACT | Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. |
| FILED | Thursday, April 07, 2011 |
| APPL NO | 13/082143 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/38 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372819 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Katherine Jones (Solana Beach, California); Lirong Zhang (San Diego, California); Vanessa Bres (San Diego, California); Yupeng Chen (San Diego, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Katherine Jones (Solana Beach, California); Lirong Zhang (San Diego, California); Vanessa Bres (San Diego, California); Yupeng Chen (San Diego, California) |
| ABSTRACT | Provided herein are methods and compositions for modulating apoptosis by targeting SKIP (Ski-interacting protein) activity. Methods of increasing DNA damage-induced cell death in cancer cells, and reducing DNA damage-induced cell death in normal cells are provided. |
| FILED | Friday, April 01, 2011 |
| APPL NO | 13/078813 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372823 | Boger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dale L. Boger (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Dale L. Boger (La Jolla, California) |
| ABSTRACT | Certain tetracyclic compounds are described, which may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis). |
| FILED | Friday, May 23, 2008 |
| APPL NO | 12/600728 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/161 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372826 | Voskuhl |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rhonda R. Voskuhl (West Hollywood, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Rhonda R. Voskuhl (West Hollywood, California) |
| ABSTRACT | The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, more particularly, Th1-mediated (cell-mediated) autoimmune diseases including: multiple sclerosis (MS), rheumatoid arthritis (RA), autoimmune thyroiditis and uveitis. Most preferably the invention is used to treat a patient with a therapeutically effective amount of estriol of 8 milligrams once daily via oral administration to treat the symptoms or prevent the onset of multiple sclerosis. |
| FILED | Monday, June 13, 2005 |
| APPL NO | 11/151040 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/182 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372839 | Ebright et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard H. Ebright (North Brunswick, New Jersey); Dongye Wang (Edison, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Richard H. Ebright (North Brunswick, New Jersey); Dongye Wang (Edison, New Jersey) |
| ABSTRACT | The invention provides a compound having a structural formula (I): X-α-Y, wherein X is an moiety that binds to the Rif pocket of a bacterial RNA polymerase, Y is a moiety that binds to the secondary channel of a bacterial RNA polymerase, and α is a linker. The compound can act as an inhibitor of bacterial RNA polymerase. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy. |
| FILED | Saturday, November 04, 2006 |
| APPL NO | 12/084018 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372848 | Houghten et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard A. Houghten (Solana Beach, California); Colette Dooley (San Diego, California); Adel Nefzi (San Diego, California); Zhiwei Wang (Irvine, California); Oliver Civelli (Irvine, California); Hiroshi Nagasaki (Nagoya, Japan) |
| ASSIGNEE(S) | Mixture Sciences, Inc. (San Diego, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard A. Houghten (Solana Beach, California); Colette Dooley (San Diego, California); Adel Nefzi (San Diego, California); Zhiwei Wang (Irvine, California); Oliver Civelli (Irvine, California); Hiroshi Nagasaki (Nagoya, Japan) |
| ABSTRACT | This invention relates generally to N-benzylamino cyclic thioureas, pharmaceutical compositions containing them, and their use as antagonists of melanin-concentrating hormone receptor (MCH receptor). |
| FILED | Wednesday, March 23, 2005 |
| APPL NO | 10/593941 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/256 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372860 | Moon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Young-Choon Moon (Belle Mead, New Jersey); Liangxian Cao (Parlin, New Jersey); Nadarajan Tamilarasu (Edison, New Jersey); Hongyan Qi (Plainsboro, New Jersey); Soongyu Choi (Skillman, New Jersey); William Joseph Lennox (South Plainfield, New Jersey); Donald Thomas Corson (Annandale, New Jersey); Seongwoo Hwang (Edison, New Jersey); Thomas Davis (South Orange, New Jersey) |
| ASSIGNEE(S) | PTC Therapeutics, Inc. (South Plainfield, New Jersey) |
| INVENTOR(S) | Young-Choon Moon (Belle Mead, New Jersey); Liangxian Cao (Parlin, New Jersey); Nadarajan Tamilarasu (Edison, New Jersey); Hongyan Qi (Plainsboro, New Jersey); Soongyu Choi (Skillman, New Jersey); William Joseph Lennox (South Plainfield, New Jersey); Donald Thomas Corson (Annandale, New Jersey); Seongwoo Hwang (Edison, New Jersey); Thomas Davis (South Orange, New Jersey) |
| ABSTRACT | In accordance with the present invention, compounds that inhibit the expression of VEGF post-transcriptionally have been identified, and methods for their use provided. In one aspect of the invention, compounds useful in the inhibition of VEGF production, in the treatment of solid tumor cancer, and in reducing plasma and/or tumor VEGF levels, are provided. In another aspect of the invention, methods are provided for the inhibition of VEGF production, the treatment of cancer, and the reduction of plasma and/or tumor VEGF levels, using the compounds of the invention. |
| FILED | Tuesday, March 02, 2010 |
| APPL NO | 12/715651 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/292 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372861 | Koong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert C. Koong (Los Altos, California); Douglas E. Feldman (Mountain View, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Albert C. Koong (Los Altos, California); Douglas E. Feldman (Mountain View, California) |
| ABSTRACT | Compounds that are inhibitors of the unfolded protein response and endonuclease IRE1 are provided, together with compositions comprising such compounds, and methods for their use in the treatment of various disorders, such as cancer, autoimmune disorders, and diabetes. Also provided are packaged pharmaceuticals comprising these compositions. The compositions may be administered in combination with another therapeutic agent. |
| FILED | Tuesday, February 27, 2007 |
| APPL NO | 12/280793 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/299 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372876 | Cahill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory M. Cahill (Houston, Texas); Oliver Rawashdeh (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Houston System (Houston, Texas) |
| INVENTOR(S) | Gregory M. Cahill (Houston, Texas); Oliver Rawashdeh (Chicago, Illinois) |
| ABSTRACT | A method for improving memory in healthy subjects is disclosed. This method makes use of melatonin receptor antagonists such as luzindole and/or K-185 to reverse the inhibitory effect of melatonin. This invention is particularly relevant among subjects that do not show signs of central nervous system disorders and wish to improve their cognitive performance, especially in tasks. |
| FILED | Thursday, March 06, 2008 |
| APPL NO | 12/043688 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372884 | Stock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffry B. Stock (Princeton, New Jersey); Maxwell Stock (Rocky Hill, New Jersey); Keshava Rapole (Edison, New Jersey); Seung-Yub Lee (Princeton, New Jersey); Michael Voronkov (Pennington, New Jersey); Eduardo Perez (Somerset, New Jersey); Joel Gordon (Princeton Junction, New Jersey); Shuyi Chen (Somerset, New Jersey); Jinglong Chen (Newark, Delaware) |
| ASSIGNEE(S) | Signum Biosciences, Inc. (Monmouth Junction, None) |
| INVENTOR(S) | Jeffry B. Stock (Princeton, New Jersey); Maxwell Stock (Rocky Hill, New Jersey); Keshava Rapole (Edison, New Jersey); Seung-Yub Lee (Princeton, New Jersey); Michael Voronkov (Pennington, New Jersey); Eduardo Perez (Somerset, New Jersey); Joel Gordon (Princeton Junction, New Jersey); Shuyi Chen (Somerset, New Jersey); Jinglong Chen (Newark, Delaware) |
| ABSTRACT | Among other things, the present invention provides novel isoprenyl compounds capable of effectively modulating inflammatory responses and pharmaceutical, cosmetic, cosmeceutical and topical compositions comprising these isoprenyl compounds. Anti-inflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with inflammation. Proinflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with suppression of inflammatory responses. Thus, the present invention also provides methods useful in the treatment or prevention of diseases or conditions associated with inflammation as well as methods useful in the treatment or prevention of diseases or conditions associated with suppression of inflammatory responses. |
| FILED | Thursday, November 12, 2009 |
| APPL NO | 12/616781 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/562 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372888 | Zipkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert E. Zipkin (Wynnewood, Pennsylvania); Sarah Spiegel (Richmond, Virginia); Jeffrey Kroll Adams (Fort Washington, Pennsylvania) |
| ASSIGNEE(S) | Enzo Therapeutics, Inc. (Farmingdale, New York) |
| INVENTOR(S) | Robert E. Zipkin (Wynnewood, Pennsylvania); Sarah Spiegel (Richmond, Virginia); Jeffrey Kroll Adams (Fort Washington, Pennsylvania) |
| ABSTRACT | Provided are novel compositions which uniquely inhibit sphingosine kinase Type 1 (SphK1) and which are useful in a number of applications including killing or damaging cancer cells, inducing apoptosis, inhibiting growth, metastasis and development of chemoresistance in cancer cells, leukemia, increasing the effectiveness of anti-cancer agents, attenuating immune reactivity, inhibiting survival signaling in cancer cells, and reducing symptoms of multiple sclerosis. |
| FILED | Wednesday, April 29, 2009 |
| APPL NO | 12/387228 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/653 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372962 | Mehta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rajeshwari R. Mehta (Orland Park, Illinois); Brad N. Taylor (Chicago, Illinois); Tohru Yamada (Oak Park, Illinois); Craig W. Beattie (Chicago, Illinois); Tapas K. Das Gupta (River Forest, Illinois); Ananda M. Chakrabarty (Villa Park, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Rajeshwari R. Mehta (Orland Park, Illinois); Brad N. Taylor (Chicago, Illinois); Tohru Yamada (Oak Park, Illinois); Craig W. Beattie (Chicago, Illinois); Tapas K. Das Gupta (River Forest, Illinois); Ananda M. Chakrabarty (Villa Park, Illinois) |
| ABSTRACT | The present invention relates to compositions comprising cupredoxins, and their use to inhibit angiogenesis in mammalian cells, tissues, and animals, and particularly the angiogenesis that accompanies tumor development and particularly in humans. Specifically, the present invention relates to compositions comprising the cupredoxin(s), and or peptides that are variants, derivatives or structural equivalents of cupredoxins, which retain the ability to inhibit angiogenesis in mammalian cells, tissues or animals. These compositions may be peptides or pharmaceutical compositions, among others. The compositions of the invention may be used to treat any pathological condition that has as a symptom or cause, inappropriate angiogenesis, and particularly inappropriate angiogenesis related to tumor development. |
| FILED | Monday, February 27, 2012 |
| APPL NO | 13/405663 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372969 | Ying et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shao-Yao Ying (San Marino, California); Shi-Lung Lin (Arcadia, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Shao-Yao Ying (San Marino, California); Shi-Lung Lin (Arcadia, California) |
| ABSTRACT | The present invention provides novel compositions and methods for suppressing the function or activity of a targeted gene through a novel intracellular piRNA-mediated RNAi mechanism, using RNA-DNA duplex constructs. The invention further provides novel methods and compositions for generating or producing RNA-DNA duplex agents, whose quantity is high enough to be used for the invention's gene silencing transfection and possibly in therapeutics applications. This improved RNA-polymerase chain reaction (RNA-PCR) method utilizes thermocycling steps of promoter-linked DNA or RNA template synthesis, in vitro transcription and then reverse transcription to bring up the amount of RNA-DNA duplexes up to two thousand folds within one round of the above procedure for using in D-RNAi-directed gene silencing. |
| FILED | Monday, October 25, 2010 |
| APPL NO | 12/911654 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372983 | Horne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David Horne (Altadena, California); Christopher Lincoln (La Canada, California) |
| ASSIGNEE(S) | City Of Hope (Duarte, California) |
| INVENTOR(S) | David Horne (Altadena, California); Christopher Lincoln (La Canada, California) |
| ABSTRACT | Provided herein are novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with the activity of the RRM1/RRM2 holoenzyme, as well as methods of synthesizing these novel compounds. The compounds may be used to inhibit RR activity and to treat various conditions associated with RRM2 expression, such as for example certain cancer types, mitochondrial diseases, or degenerative diseases. |
| FILED | Wednesday, February 01, 2012 |
| APPL NO | 13/364263 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/195 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372985 | Momiyama et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Norie Momiyama (Sendai, Japan); Hiromi Torii (Kariya, Japan); Susumu Saito (Nagoya, Japan); Hisashi Yamamoto (Chicago, Illinois); Yuhei Yamamoto (Tsukuba, Japan) |
| ASSIGNEE(S) | Japan Science and Technology Agency (Saitama, Japan) |
| INVENTOR(S) | Norie Momiyama (Sendai, Japan); Hiromi Torii (Kariya, Japan); Susumu Saito (Nagoya, Japan); Hisashi Yamamoto (Chicago, Illinois); Yuhei Yamamoto (Tsukuba, Japan) |
| ABSTRACT | The present invention is directed to a process of making α-aminooxyketone and α-hydroxyketone compounds. The synthetic pathway generally involves reacting an aldehyde or ketone substrate and a nitroso substrate in the presence of a catalyst of the formula (IV): wherein Xa-Xc represent independently nitrogen, carbon, oxygen or sulfur and Z represents a 4 to 10-membered ring with or without a substituent and optionally a further step to convert the α-aminooxyketone compound formed to the α-hydroxyketone compound. The present invention results in α-aminooxyketone and α-hydroxyketone compounds with high enantioselectivity and high purity. The present invention is also directed to a catalytic asymmetric O-nitroso Aldol/Michael reaction. The substrates of this reaction are generally cyclic α,β-unsaturated ketone substrate and a nitroso substrate. This methodology generally involves reacting the cyclic α,β-unsaturated ketone substrate and the nitroso substrate in the presence of a proline-based catalyst, to provide a heterocyclic product. |
| FILED | Friday, August 03, 2012 |
| APPL NO | 13/566587 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372986 | Fokin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Valery Fokin (Oceanside, California); Guocheng Jia (Kowloon, China Hong Kong); K. Barry Sharpless (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The Hong Kong University of Science and Technology (Kowloon, China Hong Kong) |
| INVENTOR(S) | Valery Fokin (Oceanside, California); Guocheng Jia (Kowloon, China Hong Kong); K. Barry Sharpless (La Jolla, California) |
| ABSTRACT | A convenient process for the regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles and 1,4,5-trisubstituted 1,2,3-triazoles from organic azides and alkynes employs catalytic ruthenium. |
| FILED | Friday, September 29, 2006 |
| APPL NO | 11/992696 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/255 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374371 | Miles |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ronald N. Miles (Newark Valley, New York) |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Binghamton, New York) |
| INVENTOR(S) | Ronald N. Miles (Newark Valley, New York) |
| ABSTRACT | A miniature microphone comprising a diaphragm compliantly suspended over an enclosed air volume having a vent port is provided, wherein an effective stiffness of the diaphragm with respect to displacement by acoustic vibrations is controlled principally by the enclosed air volume and the port. The microphone may be formed using silicon microfabrication techniques and has sensitivity to sound pressure substantially unrelated to the size of the diaphragm over a broad range of realistic sizes. The diaphragm is rotatively suspend for movement through an arc in response to acoustic vibrations, for example by beams or tabs, and has a surrounding perimeter slit separating the diaphragm from its support structure. The air volume behind the diaphragm provides a restoring spring force for the diaphragm. The microphone's sensitivity is related to the air volume, perimeter slit, and stiffness of the diaphragm and its mechanical supports, and not the area of the diaphragm. |
| FILED | Thursday, March 03, 2011 |
| APPL NO | 13/039994 |
| ART UNIT | 2656 — Digital Audio Data Processing |
| CURRENT CPC | Electrical audio signal processing systems and devices 381/355 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374411 | Ernst et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Michael Ernst (Honolulu, Hawaii); Thomas Edmund Prieto (Grafton, Wisconsin); Brian Stewart Randall Armstrong (Shorewood, Wisconsin) |
| ASSIGNEE(S) | The Queen's Medical Center (Honolulu, Hawaii); The University of Hawaii (Honolulu, Hawaii); The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Thomas Michael Ernst (Honolulu, Hawaii); Thomas Edmund Prieto (Grafton, Wisconsin); Brian Stewart Randall Armstrong (Shorewood, Wisconsin) |
| ABSTRACT | This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker, preferably a retro-grate reflector (RGR), is placed on an organ of interest of a patient during a scan, such as an MRI scan. The marker allows measuring the six degrees of freedom or “pose” required to track motion of the organ of interest. A detector, preferably a camera, observes the marker and continuously extracts its pose. The pose from the camera is sent to the scanner via an RGR processing computer and a scanner control and processing computer, allowing for continuous correction of scan planes and position (in real-time) for motion of the patient. This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time. |
| FILED | Tuesday, December 27, 2011 |
| APPL NO | 13/338166 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374413 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Guang-Hong Chen (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Guang-Hong Chen (Madison, Wisconsin) |
| ABSTRACT | A method for reconstructing a high quality image from undersampled image data is provided. The image reconstruction method is applicable to a number of different imaging modalities. Specifically, the present invention provides an image reconstruction method that incorporates an appropriate prior image into the image reconstruction process. Thus, one aspect of the present invention is to provide an image reconstruction method that requires less number of data samples to reconstruct an accurate reconstruction of a desired image than previous methods, such as, compressed sensing. Another aspect of the invention is to provide an image reconstruction method that imparts the signal-to-noise ratio of a prior image to the desired image being reconstructed. Another aspect of the invention is to provide an image reconstruction method that, when practiced in the field of x-ray imaging, allows for exposing a subject to substantially less radiation dose than is required in conventional x-ray imaging techniques. |
| FILED | Thursday, October 09, 2008 |
| APPL NO | 12/248590 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Image analysis 382/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374696 | Sanchez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Justin C. Sanchez (Newberry, Florida); Paul R. Camey (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Justin C. Sanchez (Newberry, Florida); Paul R. Camey (Gainesville, Florida) |
| ABSTRACT | The invention provides a micro-control neuroprosthetic device and methods for predicting and controlling epileptic neuronal activity. The device includes a detection system that detects and collects electrophysiological information comprising action potentials from single neurons and ensembles of neurons in a neural structure such as an epileptogenic region of the brain in a subject. An analysis system included in the neuroprosthetic device evaluates the electrophysiological information and performs a real-time extraction of neuron firing features from which the system determines when stimulus intervention is required. The neuroprosthetic device further comprises a stimulation intervention system that provides stimulus output signals having a desired stimulation frequency and stimulation intensity directly to the neural structure in which abnormal neuronal activity is detected. The analysis system further analyzes collected electrophysiological information during or following stimulus intervention to assess the effects of the stimulation intervention and to provide outputs to maintain or modify the stimulation intervention. |
| FILED | Wednesday, September 13, 2006 |
| APPL NO | 11/520222 |
| ART UNIT | 3766 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374698 | Ok et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerry Ok (Canyon Country, California); Robert J. Greenberg (Los Angeles, California); Neil Hamilton Talbot (Crescenta, California); James Singleton Little (Saugus, California); Rongqing Dai (Valencia, California); Jordan Matthew Neysmith (Pasadena, California); Kelly H. McClure (Simi Valley, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Jerry Ok (Canyon Country, California); Robert J. Greenberg (Los Angeles, California); Neil Hamilton Talbot (Crescenta, California); James Singleton Little (Saugus, California); Rongqing Dai (Valencia, California); Jordan Matthew Neysmith (Pasadena, California); Kelly H. McClure (Simi Valley, California) |
| ABSTRACT | The present invention is an improved hermetic package for implantation in the human body. The implantable device includes an electrically non-conductive substrate with electrically conductive vias. A flip-chip circuit is attached to the substrate using conductive bumps and electrically connected to a first subset of the vias. The flip-chip circuit can contain one or more stacks or a folded stack. A wire-bonded circuit is also attached to the substrate and electrically connected to a second subset of the vias. A cover is bonded to the substrate. The cover, substrate, and vias form an improved hermetic package for implantation. |
| FILED | Saturday, August 18, 2007 |
| APPL NO | 11/893939 |
| ART UNIT | 3766 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374828 | Jacobs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donald J Jacobs (Charlotte, North Carolina); Dennis R. Livesay (Charlotte, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Charlotte (Charlotte, North Carolina) |
| INVENTOR(S) | Donald J Jacobs (Charlotte, North Carolina); Dennis R. Livesay (Charlotte, North Carolina) |
| ABSTRACT | The computerized method, software, and product of this invention implements a process for computationally designing proteins and/or associated molecular targets with desired quantitative stability/flexibility relationships (QSFR). QSFR is an innovative, high dimensional metric calculated using an improved Distance Constraint Model (DCM). This invention includes three distinct aspects: (i.) utilizing QSFR in computational molecular design of protein sequences, or variations of molecular structures, to have specific stability and flexibility relationships deemed important for biochemical function for specified thermodynamic and solvent conditions; (ii.) utilizing QSFR to optimize thermodynamic and/or solvent conditions necessary for a specified molecular system to exhibit protein function characteristics, such as improved catalytic efficiency; and (iii.) utilizing QSFR to computationally screen or design small molecules and/or design its putative receptor so as to exhibit a desired affect on protein function. |
| FILED | Saturday, December 27, 2008 |
| APPL NO | 12/344512 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08371101 | Zuo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baifang Zuo (Greenville, South Carolina); Derrick Simons (Greenville, South Carolina); William York (Greenville, South Carolina); Willy S. Ziminsky (Greenville, South Carolina) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Baifang Zuo (Greenville, South Carolina); Derrick Simons (Greenville, South Carolina); William York (Greenville, South Carolina); Willy S. Ziminsky (Greenville, South Carolina) |
| ABSTRACT | A combustor may include an interior flow path therethrough, a number of fuel nozzles in communication with the interior flow path, and an inlet guide vane system positioned about the interior flow path to create a swirled flow therein. The inlet guide vane system may include a number of windows positioned circumferentially around the fuel nozzles. The inlet guide vane system may also include a number of inlet guide vanes positioned circumferentially around the fuel nozzles and adjacent to the windows to create a swirled flow within the interior flow path. |
| FILED | Tuesday, September 15, 2009 |
| APPL NO | 12/559522 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/39.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371173 | DiMambro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph DiMambro (Placitas, New Mexico); Dennis P. Roach (Albuquerque, New Mexico); Kirk A. Rackow (Albuquerque, New Mexico); Ciji L. Nelson (Albuquerque, New Mexico); Cameron J. Dasch (Boomfield Hills, Michigan); David G. Moore (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Joseph DiMambro (Placitas, New Mexico); Dennis P. Roach (Albuquerque, New Mexico); Kirk A. Rackow (Albuquerque, New Mexico); Ciji L. Nelson (Albuquerque, New Mexico); Cameron J. Dasch (Boomfield Hills, Michigan); David G. Moore (Albuquerque, New Mexico) |
| ABSTRACT | An ultrasonic probe deployment device in which an ultrasound-transmitting liquid forms the portion of the ultrasonic wave path in contact with the surface being inspected (i.e., the inspection surface). A seal constrains flow of the liquid, for example preventing the liquid from surging out and flooding the inspection surface. The seal is not rigid and conforms to variations in the shape and unevenness of the inspection surface, thus forming a seal (although possibly a leaky seal) around the liquid. The probe preferably is held in place to produce optimum ultrasonic focus on the area of interest. Use of encoders can facilitate the production of C-scan area maps of the material being inspected. |
| FILED | Tuesday, September 20, 2011 |
| APPL NO | 13/237520 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/629 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371647 | Ripley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edward B. Ripley (Knoxville, Tennessee) |
| ASSIGNEE(S) | Babcock and Wilcox Technical Services Y-12, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Edward B. Ripley (Knoxville, Tennessee) |
| ABSTRACT | Disclosed are various seats for vehicles particularly military vehicles that are susceptible to attack by road-bed explosive devices such as land mines or improvised explosive devices. The seats often have rigid seat shells and may include rigid bracing for rigidly securing the seat to the chassis of the vehicle. Typically embodiments include channels and particulate media such as sand disposed in the channels. A gas distribution system is generally employed to pump a gas through the channels and in some embodiments the gas is provided at a pressure sufficient to fluidize the particulate media when an occupant is sitting on the seat. |
| FILED | Tuesday, November 23, 2010 |
| APPL NO | 12/952326 |
| ART UNIT | 3636 — Static Structures, Supports and Furniture |
| CURRENT CPC | Chairs and seats 297/216.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08371816 | Piersall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew R. Piersall (Greenville, South Carolina); Brian D. Potter (Greer, South Carolina) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Matthew R. Piersall (Greenville, South Carolina); Brian D. Potter (Greer, South Carolina) |
| ABSTRACT | A tip shroud that includes a plurality of damping fins, each damping fin including a substantially non-radially-aligned surface that is configured to make contact with a tip shroud of a neighboring rotor blade. At least one damping fin may include a leading edge damping fin and at least one damping fin may include a trailing edge damping fin. The leading edge damping fin may be configured to correspond to the trailing edge damping fin. |
| FILED | Friday, July 31, 2009 |
| APPL NO | 12/533378 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/190 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372177 | Thoma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven G. Thoma (Albuquerque, New Mexico); Travis M. Anderson (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Steven G. Thoma (Albuquerque, New Mexico); Travis M. Anderson (Albuquerque, New Mexico) |
| ABSTRACT | A method to synthesize tungsten nanoparticles has been developed that enables synthesis of nanometer-scale, monodisperse particles that can be stabilized only by tetrahydrofuran. The method can be used at room temperature, is scalable, and the product concentrated by standard means. Since no additives or stabilizing surfactants are required, this method is particularly well suited for producing tungsten nanoparticles for dispersion in polymers. If complete dispersion is achieved due to the size of the nanoparticles, then the optical properties of the polymer can be largely maintained. |
| FILED | Wednesday, May 05, 2010 |
| APPL NO | 12/774212 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/362 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372369 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ralph T. Yang (Ann Arbor, Michigan); Yingwei Li (Ann Arbor, Michigan); Anthony J. Lachawiec, Jr. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Ralph T. Yang (Ann Arbor, Michigan); Yingwei Li (Ann Arbor, Michigan); Anthony J. Lachawiec, Jr. (Ann Arbor, Michigan) |
| ABSTRACT | Methods for enhancing hydrogen spillover and storage are disclosed. One embodiment of the method includes doping a hydrogen receptor with metal particles, and exposing the hydrogen receptor to ultrasonication as doping occurs. Another embodiment of the method includes doping a hydrogen receptor with metal particles, and exposing the doped hydrogen receptor to a plasma treatment. |
| FILED | Wednesday, April 20, 2011 |
| APPL NO | 13/090618 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/335 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372374 | Saykally et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard J. Saykally (Piedmont, California); Andrew M. Duffin (Oakland, California); Kevin R. Wilson (Oakland, California); Bruce S. Rude (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard J. Saykally (Piedmont, California); Andrew M. Duffin (Oakland, California); Kevin R. Wilson (Oakland, California); Bruce S. Rude (Berkeley, California) |
| ABSTRACT | A method and apparatus for producing both a gas and electrical power from a flowing liquid, the method comprising: a) providing a source liquid containing ions that when neutralized form a gas; b) providing a velocity to the source liquid relative to a solid material to form a charged liquid microjet, which subsequently breaks up into a droplet spay, the solid material forming a liquid-solid interface; and c) supplying electrons to the charged liquid by contacting a spray stream of the charged liquid with an electron source. In one embodiment, where the liquid is water, hydrogen gas is formed and a streaming current is generated. The apparatus comprises a source of pressurized liquid, a microjet nozzle, a conduit for delivering said liquid to said microjet nozzle, and a conductive metal target sufficiently spaced from said nozzle such that the jet stream produced by said microjet is discontinuous at said target. In one arrangement, with the metal nozzle and target electrically connected to ground, both hydrogen gas and a streaming current are generated at the target as it is impinged by the streaming, liquid spray microjet. |
| FILED | Wednesday, March 05, 2008 |
| APPL NO | 12/529884 |
| ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/644 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372380 | Barrio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jorge R. Barrio (Agoura Hills, California); Vladimir Kepe (Los Angeles, California); Gary W. Small (Los Angeles, California); Nagichettiar Satyamurthy (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jorge R. Barrio (Agoura Hills, California); Vladimir Kepe (Los Angeles, California); Gary W. Small (Los Angeles, California); Nagichettiar Satyamurthy (Los Angeles, California) |
| ABSTRACT | Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with 18F, 123I, 124I, 125I, or 11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions. |
| FILED | Monday, March 31, 2008 |
| APPL NO | 12/594197 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.890 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372526 | D'Andrade |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian D'Andrade (Westampton, New Jersey) |
| ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey) |
| INVENTOR(S) | Brian D'Andrade (Westampton, New Jersey) |
| ABSTRACT | A device is provided, having an anode, a cathode, and an intermediate connector disposed between the anode and the cathode. A first organic layer including an emissive sublayer is disposed between the anode and the intermediate connector, and a second including an emissive sublayer is disposed between the intermediate connector and the cathode. The intermediate connector includes a first metal having a work function lower than 4.0 eV and a second metal having a work function lower than 5.0 eV. The work function of the first metal is at least 0.5 eV less than the work function of the second metal. The first metal is in contact with a sublayer of the second organic layer that includes a material well adapted to receive holes from a low work function metal. |
| FILED | Wednesday, July 16, 2008 |
| APPL NO | 12/174286 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/690 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372626 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Min Zhang (Lakewood, Colorado); Arjun Singh (Lakewood, Colorado); Pirkko Suominen (Minnetonka, Minnesota); Eric Knoshaug (Golden, Colorado); Mary Ann Franden (Centennial, Colorado); Eric Jarvis (Boulder, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Min Zhang (Lakewood, Colorado); Arjun Singh (Lakewood, Colorado); Pirkko Suominen (Minnetonka, Minnesota); Eric Knoshaug (Golden, Colorado); Mary Ann Franden (Centennial, Colorado); Eric Jarvis (Boulder, Colorado) |
| ABSTRACT | An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains. |
| FILED | Thursday, October 21, 2010 |
| APPL NO | 12/909523 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/254.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372635 | Waldo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Geoffrey S. Waldo (Santa Fe, New Mexico); Stephanie Cabantous (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Geoffrey S. Waldo (Santa Fe, New Mexico); Stephanie Cabantous (Los Alamos, New Mexico) |
| ABSTRACT | Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited. |
| FILED | Tuesday, June 24, 2008 |
| APPL NO | 12/215081 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373119 | Reilly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter T. A. Reilly (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Peter T. A. Reilly (Knoxville, Tennessee) |
| ABSTRACT | An aerosol particle analyzer includes a laser ablation chamber, a gas-filled conduit, and a mass spectrometer. The laser ablation chamber can be operated at a low pressure, which can be from 0.1 mTorr to 30 mTorr. The ablated ions are transferred into a gas-filled conduit. The gas-filled conduit reduces the electrical charge and the speed of ablated ions as they collide and mix with buffer gases in the gas-filled conduit. Preferably, the gas filled-conduit includes an electromagnetic multipole structure that collimates the nascent ions into a beam, which is guided into the mass spectrometer. Because the gas-filled conduit allows storage of vast quantities of the ions from the ablated particles, the ions from a single ablated particle can be analyzed multiple times and by a variety of techniques to supply statistically meaningful analysis of composition and isotope ratios. |
| FILED | Monday, July 30, 2012 |
| APPL NO | 13/561365 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373133 | Dazeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven A. Dazeley (Oakland, California); Robert C. Svoboda (Davis, California); Adam Bernstein (Palo Alto, California); Nathaniel Bowden (Oakland, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Steven A. Dazeley (Oakland, California); Robert C. Svoboda (Davis, California); Adam Bernstein (Palo Alto, California); Nathaniel Bowden (Oakland, California) |
| ABSTRACT | A water Cerenkov-based neutron and high energy gamma ray detector and radiation portal monitoring system using water doped with a Gadolinium (Gd)-based compound as the Cerenkov radiator. An optically opaque enclosure is provided surrounding a detection chamber filled with the Cerenkov radiator, and photomultipliers are optically connected to the detect Cerenkov radiation generated by the Cerenkov radiator from incident high energy gamma rays or gamma rays induced by neutron capture on the Gd of incident neutrons from a fission source. The PMT signals are then used to determine time correlations indicative of neutron multiplicity events characteristic of a fission source. |
| FILED | Thursday, May 20, 2010 |
| APPL NO | 12/784390 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/366 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373372 | Su |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gui Jia Su (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Gui Jia Su (Knoxville, Tennessee) |
| ABSTRACT | The present disclosure includes electrical motor/generator drive systems and methods that significantly reduce inverter direct-current (DC) bus ripple currents and thus the volume and cost of a capacitor. The drive methodology is based on a segmented drive system that does not add switches or passive components but involves reconfiguring inverter switches and motor stator winding connections in a way that allows the formation of multiple, independent drive units and the use of simple alternated switching and optimized Pulse Width Modulation (PWM) schemes to eliminate or significantly reduce the capacitor ripple current. |
| FILED | Tuesday, September 21, 2010 |
| APPL NO | 12/887110 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Motive power systems 318/400.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374709 | Lou |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xinsheng Lou (West Hartford, Connecticut) |
| ASSIGNEE(S) | ALSTOM Technology Ltd (Baden, Switzerland) |
| INVENTOR(S) | Xinsheng Lou (West Hartford, Connecticut) |
| ABSTRACT | A system for optimizing a power plant includes a chemical loop having an input for receiving an input parameter (270) and an output for outputting an output parameter (280), a control system operably connected to the chemical loop and having a multiple controller part (230) comprising a model-free controller. The control system receives the output parameter (280), optimizes the input parameter (270) based on the received output parameter (280), and outputs an optimized input parameter (270) to the input of the chemical loop to control a process of the chemical loop in an optimized manner. |
| FILED | Friday, February 27, 2009 |
| APPL NO | 12/394509 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08375070 | Shinde et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pravin Shinde (Austin, Texas); Eric Van Hensbergen (Austin, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Pravin Shinde (Austin, Texas); Eric Van Hensbergen (Austin, Texas) |
| ABSTRACT | A mechanism is provided for group communications using a MULTI-PIPE synthetic file system. A master application creates a multi-pipe synthetic file in the MULTI-PIPE synthetic file system, the master application indicating a multi-pipe operation to be performed. The master application then writes a header-control block of the multi-pipe synthetic file specifying at least one of a multi-pipe synthetic file system name, a message type, a message size, a specific destination, or a specification of the multi-pipe operation. Any other application participating in the group communications then opens the same multi-pipe synthetic file. A MULTI-PIPE file system module then implements the multi-pipe operation as identified by the master application. The master application and the other applications then either read or write operation messages to the multi-pipe synthetic file and the MULTI-PIPE synthetic file system module performs appropriate actions. |
| FILED | Thursday, September 02, 2010 |
| APPL NO | 12/874267 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/822 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08375197 | Faraj |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ahmad Faraj (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ahmad Faraj (Rochester, Minnesota) |
| ABSTRACT | Methods, apparatus, and products are disclosed for performing an allreduce operation on a plurality of compute nodes of a parallel computer, each node including at least two processing cores, that include: performing, for each node, a local reduction operation using allreduce contribution data for the cores of that node, yielding, for each node, a local reduction result for one or more representative cores for that node; establishing one or more logical rings among the nodes, each logical ring including only one of the representative cores from each node; performing, for each logical ring, a global allreduce operation using the local reduction result for the representative cores included in that logical ring, yielding a global allreduce result for each representative core included in that logical ring; and performing, for each node, a local broadcast operation using the global allreduce results for each representative core on that node. |
| FILED | Wednesday, May 21, 2008 |
| APPL NO | 12/124763 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/30 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08372046 | Meng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ellis Meng (Pasadena, California); Ronalee Lo Mann (Somerville, Massachusetts) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Ellis Meng (Pasadena, California); Ronalee Lo Mann (Somerville, Massachusetts) |
| ABSTRACT | A drug delivery device may include a drug reservoir configured to contain and controllably deliver a fluidic drug. A tube may be configured to deliver the fluid from the drug reservoir through a lumen in the tube to another location. A valve wholly within the lumen of the tube may regulate the flow of the fluid through the tube without substantially diverting the direction in which the fluid flows through the tube. The valve may contain only a single member which moves during operation of the valve. The valve may be configured to regulate the flow of fluid in a bandpass manner by allowing fluid to flow through the valve only when the pressure of the fluid is above a minimum and below a maximum. The valve may be held in place within the tube solely by frictional force between the valve and a wall of the tube. |
| FILED | Friday, February 19, 2010 |
| APPL NO | 12/709188 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/246 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372358 | Groisman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Groisman (San Diego, California); Edgar Gutierrez (San Diego, California); Eugene Tkachenko (San Diego, California); Mark H. Ginsberg (San Diego, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander Groisman (San Diego, California); Edgar Gutierrez (San Diego, California); Eugene Tkachenko (San Diego, California); Mark H. Ginsberg (San Diego, California) |
| ABSTRACT | In a microfluidic system, a magnetic clamp for sealing a flexible microchannel chip includes a base formed from a magnetically-attractable material. The base supports a window for viewing the face of the microfluidic chip. A ring with magnets uniformly distributed around it is disposed over the base. A transparent disk attached to the top of the ring has an inlet and an outlet for introducing and removing a fluid medium into a cavity defined the disk, the window, the center opening of the ring and the base. An elastomer cushion is attached to the inner surface of the disk. The magnetic force between the base and the magnets on the ring compresses the cushion against the microfluidic chip so that the microchannels are sealed against the window with a uniform and reproducible pressure. |
| FILED | Monday, August 23, 2010 |
| APPL NO | 12/861686 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372374 | Saykally et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard J. Saykally (Piedmont, California); Andrew M. Duffin (Oakland, California); Kevin R. Wilson (Oakland, California); Bruce S. Rude (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard J. Saykally (Piedmont, California); Andrew M. Duffin (Oakland, California); Kevin R. Wilson (Oakland, California); Bruce S. Rude (Berkeley, California) |
| ABSTRACT | A method and apparatus for producing both a gas and electrical power from a flowing liquid, the method comprising: a) providing a source liquid containing ions that when neutralized form a gas; b) providing a velocity to the source liquid relative to a solid material to form a charged liquid microjet, which subsequently breaks up into a droplet spay, the solid material forming a liquid-solid interface; and c) supplying electrons to the charged liquid by contacting a spray stream of the charged liquid with an electron source. In one embodiment, where the liquid is water, hydrogen gas is formed and a streaming current is generated. The apparatus comprises a source of pressurized liquid, a microjet nozzle, a conduit for delivering said liquid to said microjet nozzle, and a conductive metal target sufficiently spaced from said nozzle such that the jet stream produced by said microjet is discontinuous at said target. In one arrangement, with the metal nozzle and target electrically connected to ground, both hydrogen gas and a streaming current are generated at the target as it is impinged by the streaming, liquid spray microjet. |
| FILED | Wednesday, March 05, 2008 |
| APPL NO | 12/529884 |
| ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/644 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372435 | Schwartz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey Schwartz (Princeton, New Jersey); Christopher A. Traina (Napa, California); Thomas Joseph Dennes (Parksburg, Pennsylvania) |
| ASSIGNEE(S) | Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Jeffrey Schwartz (Princeton, New Jersey); Christopher A. Traina (Napa, California); Thomas Joseph Dennes (Parksburg, Pennsylvania) |
| ABSTRACT | Nanoparticles are functionalized for use as bio-imaging probes using a novel, modular approach. Particle surface modification is based on a phosphonate monolayer platform on which was built a multi-segmented, multi-functional film: the first segment provided hydrolytic stability, the second aqueous suspendability, and the third, selectivity for cell attachment. In vitro imaging experiments visualized nanoparticle-cell surface binding. Peptide-derivatized nano-particles were not displaced from cells by soluble peptide. Methods for coating the host particles and use of rare earth ion-doped particles in imaging methods and photodynamic therapy methods are also disclosed. |
| FILED | Monday, June 22, 2009 |
| APPL NO | 12/489242 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372470 | Hart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anastasios John Hart (Somerville, Massachusetts); Alexander Henry Slocum (Bow, New Hampshire); Lucas Carolus van Laake (Eindhover, Netherlands) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Anastasios John Hart (Somerville, Massachusetts); Alexander Henry Slocum (Bow, New Hampshire); Lucas Carolus van Laake (Eindhover, Netherlands) |
| ABSTRACT | A method and apparatus providing controlled growth and assembly of nanostructures is presented. A first substrate including at least one reaction site is provided. Energy is provided to the reaction site and a reaction species is introduced to the first substrate. A nanostructure is grown from the reaction site. The growth process of the nanostructure is controlled while continuously monitoring the properties of at least one of the nanostructure and the at least one reaction site, and by controlling process variables based on the monitored properties of the nanostructure and the at least one reaction site. |
| FILED | Wednesday, October 25, 2006 |
| APPL NO | 11/586310 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372600 | Sachs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederick Sachs (Eden, New York); Zonglu Hua (Williamsville, New York); Stephen Besch (Buffalo, New York); Harsh Deep Chopra (Williamsville, New York); Philip Gottlieb (Buffalo, New York) |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
| INVENTOR(S) | Frederick Sachs (Eden, New York); Zonglu Hua (Williamsville, New York); Stephen Besch (Buffalo, New York); Harsh Deep Chopra (Williamsville, New York); Philip Gottlieb (Buffalo, New York) |
| ABSTRACT | A method and apparatus for measuring changes in cell volume generally includes introducing cells into a chamber having a volume between 2 and 100 times the volume of the introduced cell. A first electrically conductive extracellular fluid is introduced into the chamber and a current is applied. The voltage induced by said current flow is measured. The first fluid is exchanged with a second electrically conductive extracellular fluid and a current is applied. The voltage induced by said current flow is measured. The first induced voltage result and the second induced voltage result are used in conjunction with known voltages induced by such current flows to monitor changes in the volume corresponding to fluid flow between the cell and an extracellular fluid. |
| FILED | Wednesday, February 25, 2009 |
| APPL NO | 12/380232 |
| ART UNIT | 1775 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/39 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372891 | Schlenoff |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph B. Schlenoff (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Joseph B. Schlenoff (Tallahassee, Florida) |
| ABSTRACT | A method of reshaping an article comprising a polyelectrolyte complex, the polyelectrolyte complex comprising an intermolecular blend of a predominantly positively-charged polyelectrolyte and a predominantly negatively charged polyelectrolyte by controlling the salt doping level. |
| FILED | Friday, September 07, 2012 |
| APPL NO | 13/606122 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08372928 | Gleason et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karen K. Gleason (Lexington, Massachusetts); Jingjing Xu (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Karen K. Gleason (Lexington, Massachusetts); Jingjing Xu (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed is a substantially alternating copolymer that is conformal, hard, flexible, and has low oxygen permeability. Also disclosed is an iCVD-based method of coating a substrate with the substantially alternating copolymer. |
| FILED | Friday, May 20, 2011 |
| APPL NO | 13/112489 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 526/271 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373023 | Cunningham, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francis X. Cunningham, Jr. (Chevy Chase, Maryland) |
| ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Francis X. Cunningham, Jr. (Chevy Chase, Maryland) |
| ABSTRACT | Two sequences of a nucleic acid isolated from a cDNA library of the flowering plant Adonis aestivalis is disclosed (SEQ ID NO: 5). The first DNA sequence, referred to as AdKC28, encodes for a polypeptide (SEQ ID NO: 6) that acts in conjunction with polypeptides encoded by either one of two other closely-related Adonis aestivalis cDNAs, AdKeto1 (SEQ ID NO: 1) and AdKeto2 (SEQ ID NO: 2), to convert β-carotene (β,β-carotene) into astaxanthin (3,3′-dihydroxy-4,4′-diketo-β, β-carotene). A second DNA sequence, referred to as AdKCl 7 is also disclosed (FIG. 9). Together, these Adonis aestivalis cDNAs, when operably linked to promoters appropriate to the transgenic host, enable the production of astaxanthin and other carotenoids with 3-hydroxy-4-keto-β-rings in a variety of host cells and organisms. |
| FILED | Friday, April 20, 2007 |
| APPL NO | 12/226426 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373139 | Krishna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vijay Krishna (Gainesville, Florida); Brij M. Moudgil (Gainesville, Florida); Benjamin L. Koopman (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Vijay Krishna (Gainesville, Florida); Brij M. Moudgil (Gainesville, Florida); Benjamin L. Koopman (Gainesville, Florida) |
| ABSTRACT | Functionalized fullerenes, when excited at any of a broad range of wavelengths in an oxygen free environment, undergo luminescence. The oxygen sensitive luminescence of functionalized fullerenes is used for numerous applications including oxygen detection; irradiation induced healing of polymeric materials; and phosphors for optical location and display applications. The degradation of the functionalized fullerenes allows for the detection of oxygen by diminished luminescence when the fullerenes are exposed to an irradiation source, such as a laser beam, in the presence of oxygen. The luminescence from a portion of a surface of a material with functionalized fullerenes allows for the location of the surface containing a functionalized fullerene target in the absence of oxygen or to heat the object in the area irradiated that is exposed to oxygen. The localized heating can be used to repair defects to a material containing the functionalized fullerenes. Materials containing functionalized fullerenes can be used as phosphors in display applications. |
| FILED | Monday, January 05, 2009 |
| APPL NO | 12/810248 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/459.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373493 | Chakrabarty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Krishnendu Chakrabarty (Chapel Hill, North Carolina); Chrysovalantis Kavousianos (Ioannina, Greece); Zhaobo Zhang (San Jose, California) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Krishnendu Chakrabarty (Chapel Hill, North Carolina); Chrysovalantis Kavousianos (Ioannina, Greece); Zhaobo Zhang (San Jose, California) |
| ABSTRACT | Power switching circuits and power management techniques are provided that can reduce static power of ICs, including digital core processors. In one embodiment, the power switching circuit includes a footer (power-gating transistor) between the core and a ground rail and at least two additional power-gating transistors parallel to the footer. The power-gating transistors are controlled by respective control signals to enable selective switching. In a specific embodiment, for each sleep mode, at most, a single one of the transistors is turned on. Multiple sleep modes are accomplished according to the relative sizing of the additional power-gating transistors. A larger of the additional transistors is used to provide a standby mode during short idling times by providing a fast wake-up time and some reduction in static power. For standby modes during longer idling periods, smaller sized transistors are turned on. For longest idling periods, all transistors are turned off. |
| FILED | Wednesday, September 15, 2010 |
| APPL NO | 12/882776 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/427 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374696 | Sanchez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Justin C. Sanchez (Newberry, Florida); Paul R. Camey (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Justin C. Sanchez (Newberry, Florida); Paul R. Camey (Gainesville, Florida) |
| ABSTRACT | The invention provides a micro-control neuroprosthetic device and methods for predicting and controlling epileptic neuronal activity. The device includes a detection system that detects and collects electrophysiological information comprising action potentials from single neurons and ensembles of neurons in a neural structure such as an epileptogenic region of the brain in a subject. An analysis system included in the neuroprosthetic device evaluates the electrophysiological information and performs a real-time extraction of neuron firing features from which the system determines when stimulus intervention is required. The neuroprosthetic device further comprises a stimulation intervention system that provides stimulus output signals having a desired stimulation frequency and stimulation intensity directly to the neural structure in which abnormal neuronal activity is detected. The analysis system further analyzes collected electrophysiological information during or following stimulus intervention to assess the effects of the stimulation intervention and to provide outputs to maintain or modify the stimulation intervention. |
| FILED | Wednesday, September 13, 2006 |
| APPL NO | 11/520222 |
| ART UNIT | 3766 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374848 | Birnbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence A. Birnbaum (Evanston, Illinois); Kristian J. Hammond (Chicago, Illinois); Nicholas D. Allen (Chicago, Israel); John R. Templon (Chicago, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Lawrence A. Birnbaum (Evanston, Illinois); Kristian J. Hammond (Chicago, Illinois); Nicholas D. Allen (Chicago, Israel); John R. Templon (Chicago, Illinois) |
| ABSTRACT | A system and method for automatically generating a narrative story receives data and information pertaining to a domain event. The received data and information and/or one or more derived features are then used to identify a plurality of angles for the narrative story. The plurality of angles is then filtered, for example through use of parameters that specify a focus for the narrative story, length of the narrative story, etc. Points associated with the filtered plurality of angles are then assembled and the narrative story is rendered using the filtered plurality of angles and the assembled points. |
| FILED | Thursday, May 13, 2010 |
| APPL NO | 12/779668 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08371177 | Ihrke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chris A. Ihrke (Hartland, Michigan); Lyndon Bridgwater (Houston, Texas); Robert Platt (Houston, Texas) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Chris A. Ihrke (Hartland, Michigan); Lyndon Bridgwater (Houston, Texas); Robert Platt (Houston, Texas) |
| ABSTRACT | A tendon tension sensor that has particular application for measuring tension on a tendon employed in a robotic arm. The tension sensor includes an elastic element having a curved channel through which the tendon is threaded. The elastic element also includes a center portion on which strain gauges are mounted that measure the strain on the elastic element. Tension on the tendon causes the center portion of the elastic element to flex or bend, which is measured by the strain gauges providing an indication of the tension in the tendon. |
| FILED | Tuesday, September 30, 2008 |
| APPL NO | 12/241309 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/760 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373175 | Okojie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert S. Okojie (Cleveland, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert S. Okojie (Cleveland, Ohio) |
| ABSTRACT | Simultaneous formation of electrical ohmic contacts to silicon carbide (SiC) semiconductor having donor and acceptor impurities (n- and p-type doping, respectively) is disclosed. The innovation provides for ohmic contacts formed on SiC layers having n- and p-doping at one process step during the fabrication of the semiconductor device. Further, the innovation provides a non-discriminatory, universal ohmic contact to both n- and p-type SiC, enhancing reliability of the specific contact resistivity when operated at temperatures in excess of 600° C. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791276 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/77 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08373608 | Drexler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerome P. Drexler (Wyoming, Minnesota); Robert C. Becker (Eden Prairie, Minnesota); David W. Meyers (Brooklyn Park, Minnesota); Kelly P. Muldoon (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Jerome P. Drexler (Wyoming, Minnesota); Robert C. Becker (Eden Prairie, Minnesota); David W. Meyers (Brooklyn Park, Minnesota); Kelly P. Muldoon (Minneapolis, Minnesota) |
| ABSTRACT | A method of verifying programmable antenna configurations is disclosed. The method comprises selecting a desired antenna configuration from a plurality of antenna configuration patterns, with the selected antenna configuration forming at least one reconfigurable antenna from reconfigurable antenna array elements. The method validates the formation of the selected antenna configuration to determine antenna performance of the at least one reconfigurable antenna. |
| FILED | Wednesday, December 05, 2007 |
| APPL NO | 11/951023 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/757 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08372614 | Stewart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wilbur W. Widmer (Winter Haven, Florida); Karel Grohmann (Davenport, Florida); Mark Wilkins (Stillwater, Oklahoma) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | David Stewart (Boca Raton, Florida); Wilbur W. Widmer (Winter Haven, Florida); Karel Grohmann (Davenport, Florida); Mark Wilkins (Stillwater, Oklahoma) |
| ABSTRACT | Method for producing ethanol from solid citrus waste by reducing the concentration of limonene in citrus waste to allow fermentation. In one embodiment ground solid citrus waste is partially hydrolyzed and pasteurized by heating using a jet cooker and then injected into a flash tank to remove limonene. The heated citrus waste is then cooled, hydrolyzed with enzymes and fermented to ethanol. The remaining solids and liquids may be processed further to yield other byproducts. More particularly, the solids may be dried and pressed for use in cattle feed and the liquids may be further fermented or processed to yield additional ethanol, acetate, galacturonic acid monomers and polymers, five carbon sugars and other products. |
| FILED | Monday, April 09, 2007 |
| APPL NO | 11/784719 |
| ART UNIT | 1775 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08371534 | Goodzeit et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Neil E. Goodzeit (Princeton, New Jersey); Harald J. Weigl (Doylestown, Pennsylvania); Michael Brett McMickell (Scottsdale, Arizona); Timothy Andrew Hindle (Peoria, Arizona) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland); Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Neil E. Goodzeit (Princeton, New Jersey); Harald J. Weigl (Doylestown, Pennsylvania); Michael Brett McMickell (Scottsdale, Arizona); Timothy Andrew Hindle (Peoria, Arizona) |
| ABSTRACT | A system for isolating vibration among a plurality of instruments on a spacecraft includes at least two platforms, each of which is configured to couple to and isolate vibration for a single one of the plurality of instruments. Each of the at least two platforms is configured to mount to the spacecraft. A device is also provided for isolating vibration for one instrument among a plurality of instruments on a spacecraft. |
| FILED | Wednesday, August 06, 2008 |
| APPL NO | 12/187299 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/173.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08372641 | Westenfelder |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christof Westenfelder (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah); U.S. Department of Veteran Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Christof Westenfelder (Salt Lake City, Utah) |
| ABSTRACT | Methods described include methods of treating T1DM, the method comprising delivering a therapeutic amount of β-MSC to a subject in need thereof. Further disclosed are fusion cells comprising and MSC and a second cell wherein the nuclei of the MSC and the second cell are not fused in the fusion cell. |
| FILED | Friday, February 17, 2012 |
| APPL NO | 13/399750 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/366 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 08373127 | Ragucci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anthony J. Ragucci (Bryan, Texas); John Lusher (Bryan, Texas) |
| ASSIGNEE(S) | Lynntech, Inc. (College Station, Texas) |
| INVENTOR(S) | Anthony J. Ragucci (Bryan, Texas); John Lusher (Bryan, Texas) |
| ABSTRACT | A system and method are used to search for a thermal target from a moving aerial platform. The system includes a computer corrected to a wide field-of-view thermal imager, a narrow field-of-view thermal imager, a global navigation satellite system receiver, and an inertial navigation system. The wide field-of-view thermal imager acouires multiple images as the wide field-of-view thermal imager moves relative to a search area. Each point of each imaoe is correlated to a stationary position within the search area. The computer is configured to independently time-average the thermal signal amplitude emanating from each stationary sector in the search area imaged bv the wide field-of-view thermal imager. and direct the narrow field-of-view thermal imager to point to the stationary position of the sector of interest and display a thermal imaoe associated with the sector of interest to a user. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/491720 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/346 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08373595 | Hoover |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Hoover (Matheson, Colorado) |
| ASSIGNEE(S) | On Target Enterprises, Inc. (, None) |
| INVENTOR(S) | John Hoover (Matheson, Colorado) |
| ABSTRACT | Provided is a simultaneous radio detection and bearing system. More specifically, the radio detection and bearing system includes an RF conditioning subsystem having a plurality of First Frequency Range and Second Frequency Range signal receiving channels. The RF conditioning subsystem operable to combine First Frequency Range and Second Frequency Range signals as a first internal data stream. A coherent multi-channel digitizer subsystem is coupled to the RF conditioning system, the coherent multi-channel digitizer subsystem operable to generate a time domain snapshot of the first internal data stream. An audio recording subsystem is also coupled to the RF conditioning subsystem. A processor is coupled to the coherent multi-channel digitizer subsystem and the audio recording subsystem. The processor is operable to transform the time domain snapshot to a frequency spectrum and identify at least one signal above a threshold at a determined frequency, determine the bearing of the signal, and provide the determined frequency to the audio recording subsystem. The audio subsystem contemporaneously records the signal upon the determined frequency. An associated method of radio detection and bearing determination is also provided. |
| FILED | Monday, November 30, 2009 |
| APPL NO | 12/627767 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/428 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08372884 | Stock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffry B. Stock (Princeton, New Jersey); Maxwell Stock (Rocky Hill, New Jersey); Keshava Rapole (Edison, New Jersey); Seung-Yub Lee (Princeton, New Jersey); Michael Voronkov (Pennington, New Jersey); Eduardo Perez (Somerset, New Jersey); Joel Gordon (Princeton Junction, New Jersey); Shuyi Chen (Somerset, New Jersey); Jinglong Chen (Newark, Delaware) |
| ASSIGNEE(S) | Signum Biosciences, Inc. (Monmouth Junction, None) |
| INVENTOR(S) | Jeffry B. Stock (Princeton, New Jersey); Maxwell Stock (Rocky Hill, New Jersey); Keshava Rapole (Edison, New Jersey); Seung-Yub Lee (Princeton, New Jersey); Michael Voronkov (Pennington, New Jersey); Eduardo Perez (Somerset, New Jersey); Joel Gordon (Princeton Junction, New Jersey); Shuyi Chen (Somerset, New Jersey); Jinglong Chen (Newark, Delaware) |
| ABSTRACT | Among other things, the present invention provides novel isoprenyl compounds capable of effectively modulating inflammatory responses and pharmaceutical, cosmetic, cosmeceutical and topical compositions comprising these isoprenyl compounds. Anti-inflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with inflammation. Proinflammatory compounds of the present invention are useful in treating or preventing diseases or conditions associated with suppression of inflammatory responses. Thus, the present invention also provides methods useful in the treatment or prevention of diseases or conditions associated with inflammation as well as methods useful in the treatment or prevention of diseases or conditions associated with suppression of inflammatory responses. |
| FILED | Thursday, November 12, 2009 |
| APPL NO | 12/616781 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/562 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08372944 | Perez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | J. Manuel Perez (Orlando, Florida); Santimukul Santra (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | J. Manuel Perez (Orlando, Florida); Santimukul Santra (Orlando, Florida) |
| ABSTRACT | A method of making a hyperbranched amphiphilic polyester compound includes drying under vacuum a mixture of 2-(4-hydroxybutyl)-malonic acid and p-toluene sulphonic acid as catalyst. The vacuum is then released with a dry inert gas after drying. The dried mixture is heated under the inert gas at a temperature sufficient for polymerization. The inert gas is evacuated while continuing to heat the mixture. The formed polymer is then dissolved in dimethylformamide and precipitated out by adding methanol. Modifications of the method yield nanoparticles of polyesters having properties suited for coencapsulating fluorescent dyes together with therapeutic drugs, resulting in theranostic nanoparticles, that is, nanoparticles useful in both therapeutic treatments and diagnostic methods. |
| FILED | Thursday, April 02, 2009 |
| APPL NO | 12/417017 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Synthetic resins or natural rubbers 528/271 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374832 | Kletecka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher S. Kletecka (Willoughby Hills, Ohio); Patrick L. Ponsardin (Placitas, New Mexico); Jeromy P. Rezac (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Exelis Inc. (McLean, Virginia) |
| INVENTOR(S) | Christopher S. Kletecka (Willoughby Hills, Ohio); Patrick L. Ponsardin (Placitas, New Mexico); Jeromy P. Rezac (Albuquerque, New Mexico) |
| ABSTRACT | Techniques are provided for simulating dissemination of at least one target substance in a scene that has been contaminated with the at least one target substance. Data is received from a user to select at least one target substance whose dissemination is to be simulated as well as parameters for the scene within which the simulation is to be performed. Simulation of the dissemination is performed and data can be displayed to illustrate, statistically and/or graphically, the results of the simulation. The simulation may include simulating interrogation of at least one surface in the scene with a sensor that detects ambient or scattered radiation from the at least one surface. Data may then be generated that indicates overlap of an interrogation spot of the sensor with the at least one target substance on at least one surface in the scene. A user may change parameters and repeat the simulation. The data generated by the simulation techniques is useful in designing sensors as well as developing strategies for deployment of sensors for certain applications. |
| FILED | Thursday, December 06, 2007 |
| APPL NO | 11/951679 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08374854 | Douglas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott C. Douglas (University Park, Texas); Malay Gupta (Schaumburg, Illinois) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | Scott C. Douglas (University Park, Texas); Malay Gupta (Schaumburg, Illinois) |
| ABSTRACT | The present invention describes a speech enhancement method using microphone arrays and a new iterative technique for enhancing noisy speech signals under low signal-to-noise-ratio (SNR) environments. A first embodiment involves the processing of the observed noisy speech both in the spatial- and the temporal-domains to enhance the desired signal component speech and an iterative technique to compute the generalized eigenvectors of the multichannel data derived from the microphone array. The entire processing is done on the spatio-temporal correlation coefficient sequence of the observed data in order to avoid large matrix-vector multiplications. A further embodiment relates to a speech enhancement system that is composed of two stages. In the first stage, the noise component of the observed signal is whitened, and in the second stage a spatio-temporal power method is used to extract the most dominant speech component. In both the stages, the filters are adapted using the multichannel spatio-temporal correlation coefficients of the data and hence avoid large matrix vector multiplications. |
| FILED | Friday, March 27, 2009 |
| APPL NO | 12/413070 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 12, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130212.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page