FedInvent™ Patents
Patent Details for Tuesday, February 26, 2013
This page was updated on Monday, March 27, 2023 at 03:44 AM GMT
Department of Defense (DOD)
| US 08381510 | Brown |
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| FUNDED BY |
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| APPLICANT(S) | Harold Brown (Mason, Ohio) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Harold Brown (Mason, Ohio) |
| ABSTRACT | A method and systems for controlling a thrust output of a gas turbine engine are provided. The system includes a first sensor for measuring a first engine operating parameter, a second sensor for measuring a first engine condition parameter, and a processor programmed to determine an expected value of the first engine condition parameter and determine a first variance value using a difference between the expected value of the first engine condition parameter and the measured first engine condition parameter. The processor is further programmed to determine a trim value using the first variance value and a first engine operating parameter demand and to determine a modified operating parameter demand based on the nominal operating parameter demand and the determined trim value. The system also includes a controller coupled to the processor for controlling engine thrust based on the modified demand of the first engine operating parameter. |
| FILED | Thursday, April 30, 2009 |
| APPL NO | 12/433545 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/233 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381513 | Schreurs et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bart Hubert Schreurs (Waltzing, Belgium); Derk Geurts (Calmus, Luxembourg) |
| ASSIGNEE(S) | Delphi Technologies Holding S.arl (Troy, Michigan) |
| INVENTOR(S) | Bart Hubert Schreurs (Waltzing, Belgium); Derk Geurts (Calmus, Luxembourg) |
| ABSTRACT | A compression-ignition internal combustion engine system having an exhaust passage and an exhaust gas treatment arrangement, wherein the exhaust gas treatment arrangement comprises a three-way catalytic converter. |
| FILED | Thursday, July 24, 2008 |
| APPL NO | 12/599543 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381533 | Smoke et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jason Smoke (Phoenix, Arizona); Bob Mitlin (Scottsdale, Arizona); Alexander MirzaMoghadam (Phoenix, Arizona) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Jason Smoke (Phoenix, Arizona); Bob Mitlin (Scottsdale, Arizona); Alexander MirzaMoghadam (Phoenix, Arizona) |
| ABSTRACT | An apparatus for cooling turbine blades in a turbine engine including a direct transfer axial tangential onboard injector (TOBI) for a turbine rotor and a self-supporting seal plate disposed on a rotating disk for the turbine engine. The TOBI includes a plurality of openings emanating a flow of cooling air. The self-supporting seal plate comprises a plurality of shaped cooling holes in fluid communication with the flow of cooling air emanating from the TOBI. The rotating disk includes a plurality of turbine blade slots formed therein. The plurality of cooling holes are in fluid communication with the plurality of turbine blade slots for directing the flow of cooling air to provide cooling to the plurality of turbine blades. The plurality of openings, the plurality of cooling holes and the plurality of turbine blade slots are in axial alignment and optimized to minimize radial and hoop stresses. |
| FILED | Thursday, April 30, 2009 |
| APPL NO | 12/433634 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/806 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381584 | Robinson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Charles W. Robinson (Santa Fe, New Mexico); William F. Burns, III (San Diego, California) |
| ASSIGNEE(S) | M Ship Co., LLC (San Diego, California) |
| INVENTOR(S) | Charles W. Robinson (Santa Fe, New Mexico); William F. Burns, III (San Diego, California) |
| ABSTRACT | A model hull testing method, platform, and system are disclosed that acquire model hull performance data about one or more hulls in an open-water environment, preferably testing two hulls simultaneously as they encounter essentially the same sea state. Avoiding tow-tank testing by providing a powered watercraft as an open-water testing platform, the method proceeds by supporting the model hulls on the testing platform, so they float in outboard positions, and then by acquiring data about hull performance as the testing platform and model hulls move together through an open body of water. A complement of data acquisition components acquires digital and analog data about the testing environment and model hull performance, preferably including platform motion, time and location information, wave characteristics, apparent wind speed and direction, and model hull drag and motion, with all data being recorded on an onboard laptop computer for later processing and analysis. A trimaran powered watercraft configuration and preferred data-acquisition components and techniques are also disclosed. |
| FILED | Monday, July 25, 2011 |
| APPL NO | 13/136149 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/170.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381651 | Presutti, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas Michael Presutti, Jr. (Long Valley, New Jersey); Nicholas Liggett Grossman (Sparta, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Thomas Michael Presutti, Jr. (Long Valley, New Jersey); Nicholas Liggett Grossman (Sparta, New Jersey) |
| ABSTRACT | A rotational variable pyrotechnic delay selector for munitions which permits the selection of various ignition delays. Advantageously, the variable delay selector is configurable for a variety of field conditions and targets and is adaptable to a number of munitions systems and pyrotechnic ignition mixtures and delays. |
| FILED | Thursday, September 01, 2011 |
| APPL NO | 13/223722 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381656 | Woo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Timothy Woo (Flushing, New York); Leon Moy (Montclair, New Jersey); Bishara Elmasri (Landing, New Jersey); Christina Morales (Mine Hill, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Timothy Woo (Flushing, New York); Leon Moy (Montclair, New Jersey); Bishara Elmasri (Landing, New Jersey); Christina Morales (Mine Hill, New Jersey) |
| ABSTRACT | To hinder activation caused by unplanned stimuli, a munition may include first and second discrete, separable parts. The first and second parts may include interlocking components to prevent relative axial translation of the first and second parts. The first and second parts may be torsionally biased in opposite directions. A binder with a low melting temperature may fix the first and second parts together to prevent the torsional bias from rotating the first and second parts in the opposite directions. When the binder melts, the torsional bias may cause the first part to rotate with respect to the second part. Relative rotation of the first and second parts may allow relative axial translation of the first and second parts. |
| FILED | Friday, September 09, 2011 |
| APPL NO | 13/228735 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/481 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381657 | Hooke |
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| FUNDED BY |
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| APPLICANT(S) | Ryan Hooke (Sparta, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ryan Hooke (Sparta, New Jersey) |
| ABSTRACT | An enhanced grenade exhibiting improved insensitive munitions (IM) characteristics while providing improved lethality or non-lethality as desired. |
| FILED | Friday, July 01, 2011 |
| APPL NO | 13/174985 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/487 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381672 | Eriksen |
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| FUNDED BY |
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| APPLICANT(S) | Charles C. Eriksen (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Charles C. Eriksen (Seattle, Washington) |
| ABSTRACT | Systems and methods for compensating for compressibility and thermal expansion coefficient mismatch in buoyancy controlled or buoyancy-driven underwater vehicles are disclosed herein. An underwater vehicle configured in accordance with one embodiment of the disclosure, for example, can include a hull and a compartment carried by the hull and at least partially flooded with a first liquid having similar properties as a surrounding liquid into which the hull is configured to be deployed. The first liquid has a first compressibility and thermal expansion coefficient. The underwater vehicle can further include a compressibility and thermal expansion coefficient compensation system comprising a container filled or at least partially filled with a compressible liquid comprising silicone in the compartment. The compressible liquid has a second compressibility higher than the first compressibility and second thermal expansion coefficient higher than the first thermal expansion coefficient. The compressible liquid can include, for example, hexamethyldisiloxane (HMDS). |
| FILED | Wednesday, June 02, 2010 |
| APPL NO | 12/792620 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/333 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381766 | Fennimore et al. |
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| FUNDED BY |
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| APPLICANT(S) | Keith A. Fennimore (Columbus, New Jersey); John Spallone (Virginia Beach, Virginia) |
| ASSIGNEE(S) | Protonex Technology Corporation (Southborough, Massachusetts) |
| INVENTOR(S) | Keith A. Fennimore (Columbus, New Jersey); John Spallone (Virginia Beach, Virginia) |
| ABSTRACT | Systems and methods are provided for hydrogen generation utilizing two or more liquid fuel components, using a fuel delivery system comprising a single reversible or bi-directional pump co-operable with flow control means comprising passive or active valves to deliver two or more fuel components to a mixing zone, reaction zone, or reaction chamber of a hydrogen generation system. The pump is operable in a forward direction to deliver one fuel component, and in a reverse direction to deliver a second fuel component. Control of the pump speed, direction and duty cycle of the pump in continuous or pulsed modes provides for delivery of first and second fuel components in desired proportions, to control hydrogen generation. The system also allows for dilution, mixing and flush cycles to be provided using a single pump, reducing the number of active elements required for fuel delivery and flow control in systems using two or more liquid fuel components. |
| FILED | Thursday, March 06, 2008 |
| APPL NO | 12/043386 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Fluid handling 137/565.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382041 | Yechout |
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| FUNDED BY |
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| APPLICANT(S) | Thomas R. Yechout (Colorado Springs, Colorado) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Thomas R. Yechout (Colorado Springs, Colorado) |
| ABSTRACT | A rakelet comprises a raked portion and a winglet portion that selectively integrate features of raked wingtips and winglets into a wingtip device that improves aircraft endurance and range over standard wings and over other wingtip devices such as raked wings, winglets, and the like. The features of the rakelet can be configured to improve and maximize the range and endurance for any particular aircraft. |
| FILED | Wednesday, August 04, 2010 |
| APPL NO | 12/849849 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/199.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382082 | Meeks et al. |
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| FUNDED BY |
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| APPLICANT(S) | Daniel Gath Meeks (Imperial Beach, California); Wendy Marie Massey (La Jolla, California); William George Cheyne (Tucson, Arizona) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Gath Meeks (Imperial Beach, California); Wendy Marie Massey (La Jolla, California); William George Cheyne (Tucson, Arizona) |
| ABSTRACT | A method for horizontal assembly of a high-voltage feed-through bushing includes vertically-assembling a field shaper assembly of a high-voltage feed-through bushing on a field shaper fixture. The field shaper assembly is then rotated within the field shaper fixture such that the field shaper assembly is oriented on a horizontal axis. Next, an insulator tube fixture supporting an insulator tube assembly is positioned adjacent to the field shaper fixture. The insulator tube assembly, being oriented on the same horizontal axis as the field shaper assembly, is then affixed to field shaper assembly. |
| FILED | Tuesday, July 20, 2010 |
| APPL NO | 12/839562 |
| ART UNIT | 3727 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Work holders 269/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382174 | Desai et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jaydev P. Desai (Bethesda, Maryland); Chad Kessens (Rosedale, Maryland) |
| ASSIGNEE(S) | University of Maryland (College Park, Maryland); Motile Robotics, Inc. (Joppa, Maryland) |
| INVENTOR(S) | Jaydev P. Desai (Bethesda, Maryland); Chad Kessens (Rosedale, Maryland) |
| ABSTRACT | A suction gripper includes a cup member, a suction port, and a valve. The cup member has inner and outer surfaces defining an opening such that the inner surface defines an inner cavity. The suction port provides suction. The valve in is fluid communication with the suction port and the inner cavity of the cup member to modify the suction therebetween. The valve is operatively coupled to the cup member and is adapted to passively actuate in response to an applied force to the cup member. |
| FILED | Friday, October 08, 2010 |
| APPL NO | 12/901241 |
| ART UNIT | 3652 — Material and Article Handling |
| CURRENT CPC | Handling: Hand and hoist-line implements 294/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382432 | Grissino et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alan Scott Grissino (Amesbury, Massachusetts); Jeremy Stephen Wigon (Topsfield, Massachusetts); Gianni Emanuolo Busso (Watertown, Massachusetts) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Alan Scott Grissino (Amesbury, Massachusetts); Jeremy Stephen Wigon (Topsfield, Massachusetts); Gianni Emanuolo Busso (Watertown, Massachusetts) |
| ABSTRACT | A rim seal assembly includes an annular seal element circumscribing an engine centerline or axis and mounted on an annular platform including a radially inwardly extending annular platform flange disposed between and connected to forward and aft flanges at distal ends of forward and aft annular elements respectively. Annular forward and aft outer rim cavities radially disposed between the forward and aft annular elements and the platform are axially separated by the platform flange. Cooling slots extend radially across axially facing forward and aft surfaces of the forward and aft flanges. The platform flange and the forward and aft flanges are bolted together. The annular seal element may include seal teeth in sealing relationship with an annular seal land such as in a labyrinth seal. The rim seal assembly may be incorporated in a low pressure turbine use a compressor as a source of cooling air. |
| FILED | Monday, March 08, 2010 |
| APPL NO | 12/719222 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/95 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382485 | Bardsley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ryan Scott Bardsley (Andover, Massachusetts); Mark Peter Ottensmeyer (Cambridge, Massachusetts); Joseph Thomas Samosky (Newton, Massachusetts); Steven L. Dawson (Carlisle, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ryan Scott Bardsley (Andover, Massachusetts); Mark Peter Ottensmeyer (Cambridge, Massachusetts); Joseph Thomas Samosky (Newton, Massachusetts); Steven L. Dawson (Carlisle, Massachusetts) |
| ABSTRACT | Method and apparatus to provide simulation of a human casualty. In one embodiment an autonomous casualty simulator includes a processing module having a scenario progression controller and a physiological modeling system to receive sensor input and to control effectors. The autonomous casualty simulator can be contained in a nominal human mannequin form. |
| FILED | Thursday, September 28, 2006 |
| APPL NO | 12/067260 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Education and demonstration 434/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382540 | Barnard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Andrew H. Barnard (Corvallis, Oregon); Bruce K. Rhoades (Corvallis, Oregon); John N. Koegler, III (Corvallis, Oregon); Alex R. Derr (Seal Rock, Oregon); Casey Moore (Corvallis, Oregon); Daniel R. Whiteman (Philomath, Oregon); Percy L. Donaghay (Saunderstown, Rhode Island); James M. Sullivan (Peacedale, Rhode Island) |
| ASSIGNEE(S) | Wet Labs, Inc. (Philomath, Oregon) |
| INVENTOR(S) | Andrew H. Barnard (Corvallis, Oregon); Bruce K. Rhoades (Corvallis, Oregon); John N. Koegler, III (Corvallis, Oregon); Alex R. Derr (Seal Rock, Oregon); Casey Moore (Corvallis, Oregon); Daniel R. Whiteman (Philomath, Oregon); Percy L. Donaghay (Saunderstown, Rhode Island); James M. Sullivan (Peacedale, Rhode Island) |
| ABSTRACT | A method and apparatus for controlling the motion of a cable-driven autonomous moored profiler. The profiler includes one or more buoyant members for buoying the profiler in the fluid, a winch, and a feedback controller for controlling the winch. The winch includes a spool, a device providing for varying rates of turning of the spool, and a flexible cable for winding onto and unwinding from the spool. A first end of the cable is carried by the profiler. The controller monitors an indication of the tension in the cable and controls the device in response thereto. |
| FILED | Friday, November 30, 2007 |
| APPL NO | 11/998650 |
| ART UNIT | 3617 — Electrical Circuits and Systems |
| CURRENT CPC | Buoys, rafts, and aquatic devices 441/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382917 | Johnson |
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| FUNDED BY |
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| APPLICANT(S) | Alfred David Johnson (San Leandro, California) |
| ASSIGNEE(S) | Ormco Corporation (Orange, California) |
| INVENTOR(S) | Alfred David Johnson (San Leandro, California) |
| ABSTRACT | Shape-setting methods for fabricating devices made of single crystal shape memory alloys. In particular the methods described may be used to fabricate dental arches of single-crystal shape memory alloys. The methods include drawing a single crystal of a shape memory alloy from a melt of the alloy. This is followed by heating, forming, and quenching the crystal sufficiently rapid to limit the formation of alloy precipitates to an amount which retains hyperelastic composition and properties of the crystal. |
| FILED | Monday, November 22, 2010 |
| APPL NO | 12/952002 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Metal treatment 148/562 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382921 | Laib et al. |
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| FUNDED BY |
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| APPLICANT(S) | Gerald R. Laib (Olney, Maryland); Michael Beggans (Waldorf, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gerald R. Laib (Olney, Maryland); Michael Beggans (Waldorf, Maryland) |
| ABSTRACT | An apparatus for compressing powders and the like including a head assembly with a distensible elastic platen mounted in a chambered header plate containing a pressurizing fluid. The elastic platen distends in response to the pressurizing fluid. Further, a base assembly includes a rigid platen mounted in a base plate. The rigid platen includes a face with at least one cavity, into which is added powder to be compressed. The elastic platen is aligned with the rigid platen, and during compression, the two platens may be held firmly in contact. The pressurizing fluid pumped into the head assembly causes the elastic platen to deform forming a single distention per cavity. The distensions compress the powder to an optimal density. The apparatus safely and easily compact multiple small samples of explosives and the like into miniature charges. |
| FILED | Thursday, September 11, 2008 |
| APPL NO | 12/283782 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382922 | Sengupta |
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| FUNDED BY |
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| APPLICANT(S) | Debasis Sengupta (Madison, Alabama) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Debasis Sengupta (Madison, Alabama) |
| ABSTRACT | A group of tertiary amine azides are useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH. |
| FILED | Tuesday, May 18, 2010 |
| APPL NO | 12/781842 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/92 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383014 | Vanheusden et al. |
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| FUNDED BY |
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| APPLICANT(S) | Karel Vanheusden (Placitas, New Mexico); Klaus Kunze (Albuquerque, New Mexico); Hyungrak Kim (Albuquerque, New Mexico); Aaron D. Stump (Albuquerque, New Mexico); Allen B. Schult (Albuquerque, New Mexico); Mark J. Hampden-Smith (Albuquerque, New Mexico); Chuck Edwards (Rio Rancho, New Mexico); Anthony R. James (Rio Rancho, New Mexico); James Caruso (Albuquerque, New Mexico); Toivo T. Kodas (Albuquerque, New Mexico); Scott Thomas Haubrich (Albuquerque, New Mexico); Mark H. Kowalski (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Cabot Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Karel Vanheusden (Placitas, New Mexico); Klaus Kunze (Albuquerque, New Mexico); Hyungrak Kim (Albuquerque, New Mexico); Aaron D. Stump (Albuquerque, New Mexico); Allen B. Schult (Albuquerque, New Mexico); Mark J. Hampden-Smith (Albuquerque, New Mexico); Chuck Edwards (Rio Rancho, New Mexico); Anthony R. James (Rio Rancho, New Mexico); James Caruso (Albuquerque, New Mexico); Toivo T. Kodas (Albuquerque, New Mexico); Scott Thomas Haubrich (Albuquerque, New Mexico); Mark H. Kowalski (Albuquerque, New Mexico) |
| ABSTRACT | A metal nanoparticle composition for the fabrication of conductive features. The metal nanoparticle composition advantageously has a low viscosity permitting deposition of the composition by direct-write tools. The metal nanoparticle composition advantageously also has a low conversion temperature, permitting its deposition and conversion to an electrical feature on polymeric substrates. |
| FILED | Tuesday, June 15, 2010 |
| APPL NO | 12/816210 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/512 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383036 | Sloan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mark A. Sloan (Spring Branch, Texas); Jeevalatha Vivekananda (San Antonio, Texas); Eric A. Holwitt (San Antonio, Texas); Johnathan L. Kiel (Universal City, Texas) |
| ASSIGNEE(S) | Conceptual Mindworks, Inc. (San Antonio, Texas) |
| INVENTOR(S) | Mark A. Sloan (Spring Branch, Texas); Jeevalatha Vivekananda (San Antonio, Texas); Eric A. Holwitt (San Antonio, Texas); Johnathan L. Kiel (Universal City, Texas) |
| ABSTRACT | The present invention concerns methods, compositions and apparatus for neutralizing bioagents, wherein bioagents comprise biowarfare agents, biohazardous agents, biological agents and/or infectious agents. The methods comprise exposing the bioagent to an organic semiconductor and exposing the bioagent and organic semiconductor to a source of energy. Although any source of energy is contemplated, in some embodiments the energy comprises visible light, ultraviolet, infrared, radiofrequency, microwave, laser radiation, pulsed corona discharge or electron beam radiation. Exemplary organic semiconductors include DAT and DALM. In certain embodiments, the organic semiconductor may be attached to one or more binding moieties, such as an antibody, antibody fragment, or nucleic acid ligand. Preferably, the binding moiety has a binding affinity for one or more bioagents to be neutralized. Other embodiments concern an apparatus comprising an organic semiconductor and an energy source. In preferred embodiments, the methods, compositions and apparatus are used for neutralizing anthrax spores. |
| FILED | Monday, December 20, 2010 |
| APPL NO | 12/973681 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383290 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rongzhong Jiang (Olney, Maryland); Deryn Chu (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Rongzhong Jiang (Olney, Maryland); Deryn Chu (Potomac, Maryland) |
| ABSTRACT | A passive fuel cell assembly, in which there is neither air pump, nor fuel pump, is comprised of a plurality of bi-cell units. Each bi-cell unit includes a first cell and a second cell, and each cell includes an electrode of a first polarity and an electrode of a second polarity, with an ion permeable membrane disposed therebetween. The bi-cell unit further includes a fuel container which comprises a housing defining a fuel chamber having a first and second open surface. The first and second cells are disposed on opposite sides so that electrodes of each cell having the first polarity are disposed in fluid contact with the fuel chamber. The assembly further includes an oxidizer supply member disposed between adjacent pairs of bi-cell units. The oxidizer supply member includes an oxidizer chamber having four sides to take in air, and having first and second open surfaces. The oxidizer supply member is disposed so that electrodes of the second polarity of adjacent bi-cell units are in fluid contact with the chamber of the oxidizer supply member. The various bi-cell units may be electrically interconnected in mixed series parallel relationship to obtain long operational life. The fuel cell bi-cell assembly may be configured to operate in conjunction with a liquid fuel such as an alcohol, and using air as an oxidizer. |
| FILED | Wednesday, April 28, 2010 |
| APPL NO | 12/768848 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/512 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383361 | Heller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Adam Heller (Austin, Texas); Benjamin J. Feldman (Oakland, California); Nicolas Mano (Austin, Texas); Yueh-Lin Loo (Lawrenceville, New Jersey) |
| ASSIGNEE(S) | Abbott Diabetes Care Inc. (Alameda, California) |
| INVENTOR(S) | Adam Heller (Austin, Texas); Benjamin J. Feldman (Oakland, California); Nicolas Mano (Austin, Texas); Yueh-Lin Loo (Lawrenceville, New Jersey) |
| ABSTRACT | A polymer matrix that may coated on an electrode is created by co-crosslinking (1) an adduct of a polyaniline formed by templated oxidative polymerization on a polymer acid; (2) a water-soluble crosslinker; and (3) a redox enzyme. The polymer matrix may be hydrated, and the absorbed water may make it permeable to, for example, glucose. The polyaniline may be polyaniline itself or a substituted polyaniline; the water-soluble crosslinker may be poly(ethylene glycol)diglycidyl ether, and the redox enzyme may be glucose oxidase. The polymer matrix may be produced by co-crosslinking (1) an adduct of an electrically conductive polymer and a polymer acid; (2) a water-soluble crosslinker; and (3) a redox enzyme in a single step at an about neutral pH, curing by drying. After hydration, the crosslinked polymer matrix may form a 3-dimensional glucose-permeable bioelectrocatalyst, catalyzing the electrooxidation of glucose. |
| FILED | Wednesday, December 14, 2011 |
| APPL NO | 13/326071 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383404 | Yilmaz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Omer H. Yilmaz (Ann Arbor, Michigan); Mark J. Kiel (Ann Arbor, Michigan); Sean Morrison (Ann Arbor, Michigan); Toshihide Iwashita (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Omer H. Yilmaz (Ann Arbor, Michigan); Mark J. Kiel (Ann Arbor, Michigan); Sean Morrison (Ann Arbor, Michigan); Toshihide Iwashita (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to methods of identifying, collecting and isolating hematopoietic stem cells (HSCs) and compositions of purified HSCs. Specifically, the present invention provides methods of isolating and purifying CD150+ HSCs, CD48− HSCs, and CD244− HSCs. The present invention also relates to purified cell samples with enriched CD150+ HSCs, CD48− HSCs, and CD244− HSCs populations, as well as methods of treating subjects with such compositions. |
| FILED | Monday, January 24, 2011 |
| APPL NO | 13/012139 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/372 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383416 | Poponin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vladimir Poponin (Costa Mesa, California) |
| ASSIGNEE(S) | Vladimir Poponin (Costa Mesa, California) |
| INVENTOR(S) | Vladimir Poponin (Costa Mesa, California) |
| ABSTRACT | An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are disclosed. The sensor includes a substrate, a plasmon resonance mirror formed on a sensor surface of the substrate, a plasmon resonance particle layer disposed over the mirror, and an optically transparent dielectric layer about 2-40 nm thick separating the mirror and particle layer. The particle layer is composed of a periodic array of plasmon resonance particles having (i) a coating effective to binding analyte molecules, (ii) substantially uniform particle sizes and shapes in a selected size range between 50-200 nm (ii) a regular periodic particle-to-particle spacing less than the wavelength of the laser excitation beam. The device is capable of detecting analyte with an amplification factor of up to 1012-1014, allowing detection of single analyte molecules. |
| FILED | Tuesday, January 10, 2012 |
| APPL NO | 13/347566 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383426 | Tolpygo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sergey K. Tolpygo (Putnam Valley, New York) |
| ASSIGNEE(S) | Hypres, Inc. (Elmsford, New York) |
| INVENTOR(S) | Sergey K. Tolpygo (Putnam Valley, New York) |
| ABSTRACT | An improved microfabrication technique for Josephson junctions in superconducting integrated circuits, based on the use of a double-layer lithographic mask for partial anodization of the side-walls and base electrode of the junctions. The top layer of the mask is a resist material, and the bottom layer is a dielectric material chosen so to maximize adhesion between the resist and the underlying superconducting layer, be etch-compatible with the underlying superconducting layer, and be insoluble in the resist and anodization processing chemistries. The superconductor is preferably niobium, under a silicon dioxide layer, with a conventional photoresist or electron-beam resist as the top layer. This combination results in a substantial increase in the fabrication yield of high-density superconducting integrated circuits, increase in junction uniformity and reduction in defect density. A dry etch more compatible with microlithography may be employed. |
| FILED | Monday, March 28, 2011 |
| APPL NO | 13/073954 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383520 | Marrs |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Marrs (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Michael Marrs (Phoenix, Arizona) |
| ABSTRACT | In some embodiments, a method of etching an organosiloxane dielectric material can include: (a) providing the organosiloxane dielectric material; (b) providing a patterned mask over the organosiloxane dielectric material; and (c) reactive ion etching the organosiloxane dielectric material. Other embodiments are disclosed in this application. |
| FILED | Friday, May 27, 2011 |
| APPL NO | 13/118240 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/710 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383552 | Barnes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul N. Barnes (West Milton, Ohio); Timothy J. Haugan (Beavercreek, Ohio) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Paul N. Barnes (West Milton, Ohio); Timothy J. Haugan (Beavercreek, Ohio) |
| ABSTRACT | The present invention provides a method of making a high temperature superconductor having a doped, nanoparticulate pinning structure. The method includes providing a nanoparticulate pinning material, providing a cuprate material, doping the nanoparticulate pinning material with a dopant to form a doped nanoparticulate material, depositing a layer of the cuprate material on a substrate, and depositing a layer of the doped nanoparticulate material on the layer of cuprate material. The invention also provides a high temperature superconductor (HTS) having a doped, nanoparticulate pinning structure including a plurality of layers of a cuprate material and a plurality of layers of a doped nanoparticulate pinning material. At least one layer of the doped nanoparticulate pinning material is stacked between two layers of the cuprate material. |
| FILED | Thursday, January 31, 2008 |
| APPL NO | 12/023973 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/234 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383561 | Sawyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | W. Gregory Sawyer (Gainesville, Florida); David L. Burris (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, inc. (Gainesville, Florida) |
| INVENTOR(S) | W. Gregory Sawyer (Gainesville, Florida); David L. Burris (Gainesville, Florida) |
| ABSTRACT | A PTFE-based composite material includes a PTFE major phase filled with a metal oxide minor phase. The major phase is intermixed with the metal oxide minor phase, wherein the minor phase includes a plurality of irregularly shaped metal oxide nanoparticles. The irregularly shaped nanoparticles provide substantial reductions in steady state wear rate over otherwise similar nanocomposites. The metal oxide can comprise aluminum oxide. |
| FILED | Tuesday, August 24, 2010 |
| APPL NO | 12/861985 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Solid anti-friction devices, materials therefor, lubricant or separant compositions for moving solid surfaces, and miscellaneous mineral oil compositions 58/106 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383697 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gerald O. Wilson (Champaign, Illinois); Mary M. Caruso (Urbana, Illinois); Benjamin J. Blaiszik (Urbana, Illinois); James W. Henderson (Winnetka, Illinois); Christopher Britt (St. Louis, Missouri); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois); Nancy R. Sottos (Champaign, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gerald O. Wilson (Champaign, Illinois); Mary M. Caruso (Urbana, Illinois); Benjamin J. Blaiszik (Urbana, Illinois); James W. Henderson (Winnetka, Illinois); Christopher Britt (St. Louis, Missouri); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois); Nancy R. Sottos (Champaign, Illinois) |
| ABSTRACT | A composite material precursor composition includes a matrix precursor, a first plurality of capsules including a liquid polymerizer, an activator, and an accelerant. The liquid polymerizer polymerizes when in contact with the activator, and the accelerant is an accelerant for the polymerization of the liquid polymerizer. The composite material precursor may be used to form a composite material that includes a solid polymer matrix, the first plurality of capsules in the solid polymer matrix, the activator in the solid polymer matrix, and the accelerant in the solid polymer matrix. |
| FILED | Thursday, April 29, 2010 |
| APPL NO | 12/769904 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 523/120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383719 | Abrami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siamanto Abrami (Glendale, California); Guangliang Tang (Glendale, California) |
| ASSIGNEE(S) | PRC De Soto International, Inc. (Sylmar, California) |
| INVENTOR(S) | Siamanto Abrami (Glendale, California); Guangliang Tang (Glendale, California) |
| ABSTRACT | Water-borne polyurethane coating compositions are provided. One exemplary water-borne coating composition includes a substantially water-free base component and an activator component. The substantially water-free base component includes at least a hydrophilic polyol, and the activator component includes at least a hydrophobic isocyanate. |
| FILED | Tuesday, October 23, 2007 |
| APPL NO | 11/876986 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 524/501 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383761 | Beaujuge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pierre Marc Beaujuge (Gainesville, Florida); John R. Reynolds (Gainesville, Florida); Stefan Martin Ellinger (Visp, Switzerland) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Pierre Marc Beaujuge (Gainesville, Florida); John R. Reynolds (Gainesville, Florida); Stefan Martin Ellinger (Visp, Switzerland) |
| ABSTRACT | Green to transmissive soluble electrochromic polymers are conjugated polymers having a plurality of repeating units where repeating units are a plurality of substituted dioxyheterocycle based donor groups coupled to an acceptor group. The conjugated polymer absorbs radiation within a first band of the visible spectrum and a second band of the visible spectrum when in a neutral state resulting in a green color and is transmissive when in an oxidized state. The polymers are soluble allowing processing of films and coatings from solution. |
| FILED | Wednesday, October 29, 2008 |
| APPL NO | 12/740570 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383762 | Beaujuge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pierre Marc Beaujuge (Berkeley, California); John R. Reynolds (Gainesville, Florida); Stefan Martin Ellinger (Visp, Switzerland); Chad Martin Amb (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Pierre Marc Beaujuge (Berkeley, California); John R. Reynolds (Gainesville, Florida); Stefan Martin Ellinger (Visp, Switzerland); Chad Martin Amb (Gainesville, Florida) |
| ABSTRACT | A soluble fused donor-acceptor conjugated polymer (fDA-CP) is prepared that absorbs light throughout nearly all the visible spectrum and is essentially black to the human eye when in the neutral state. The conjugated polymer has acceptor units that are isolated by a plurality of fused donor units. The fDA-CP assumes a conformation that results in a close π-stacking between adjacent lamella with a separation of less than 4.5 Å in the solid state and extended conjugation to promote high charge carrier mobilities. The fDA-CP is prepared by the polycondensation of a plurality of at least one fused donor-acceptor oligomer (fDA-oligomer) that has a flat internal acceptor unit and at least one fused donor unit incorporated in the oligomers, and optionally, an additional conjugated aromatic monomer or oligomer copolymerized with the fDA-oligomers. |
| FILED | Wednesday, November 25, 2009 |
| APPL NO | 13/130697 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383763 | McGrath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James E. McGrath (Blacksburg, Virginia); Michael Hickner (Blacksburg, Virginia); Feng Wang (Blacksburg, Virginia); Yu-Seung Kim (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | James E. McGrath (Blacksburg, Virginia); Michael Hickner (Blacksburg, Virginia); Feng Wang (Blacksburg, Virginia); Yu-Seung Kim (Blacksburg, Virginia) |
| ABSTRACT | Sulfonated polymers are made by the direct polymerization of a sulfonated monomer to form the sulfonated polymers. The types of sulfonated polymers may include polysulfones or polyimides. The sulfonated polymers can be formed into membranes that may be used in proton exchange membrane fuel cells or as ion exchange membranes. The membranes formed from the sulfonated polymers exhibit improved properties over that of Nafion®. A heteropoly acid may be added to the sulfonated polymer to form a nanocomposite membrane in which the heteropoly acid is highly dispersed. The addition of a heteropoly acid to the sulfonated polymer increases the thermal stability of the membrane, enhances the conductivity above 100° C., and reduces the water uptake of the membrane. |
| FILED | Thursday, July 29, 2010 |
| APPL NO | 12/845874 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/391 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383794 | Niu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Li Niu (Loudonville, New York); Zhen Huang (Latham, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Latham, New York) |
| ABSTRACT | The present invention relates to novel nucleic acid ligands or aptamers that demonstrate potent and selective inhibition of the open-channel conformation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. |
| FILED | Friday, October 08, 2010 |
| APPL NO | 12/900636 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384090 | Powell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Adrian Powell (Cary, North Carolina); Mark Brady (Carrboro, North Carolina); Stephan G. Mueller (Durham, North Carolina); Valeri F. Tsvetkov (Gasburg, Virginia); Robert T. Leonard (Raleigh, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Adrian Powell (Cary, North Carolina); Mark Brady (Carrboro, North Carolina); Stephan G. Mueller (Durham, North Carolina); Valeri F. Tsvetkov (Gasburg, Virginia); Robert T. Leonard (Raleigh, North Carolina) |
| ABSTRACT | A high quality single crystal wafer of SiC is disclosed having a diameter of at least about 3 inches and a 1c screw dislocation density of less than about 2000 cm−2. |
| FILED | Thursday, November 15, 2007 |
| APPL NO | 11/940454 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/77 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384122 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chenming Hu (Oakland, California); Anupama Bowonder (Berkeley, California); Pratik Patel (Berkeley, California); Daniel Chou (Houston, Texas); Prashant Majhi (Austin, Texas) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chenming Hu (Oakland, California); Anupama Bowonder (Berkeley, California); Pratik Patel (Berkeley, California); Daniel Chou (Houston, Texas); Prashant Majhi (Austin, Texas) |
| ABSTRACT | Several embodiments of a tunneling transistor are disclosed. In one embodiment, a tunneling transistor includes a semiconductor substrate, a source region formed in the semiconductor substrate, a drain region formed in the semiconductor substrate, a gate stack including a metallic gate electrode and a gate dielectric, and a tunneling junction that is substantially parallel to an interface between the metallic gate electrode and the gate dielectric. As a result of the tunneling junction that is substantially parallel with the interface between the metallic gate electrode and the gate dielectric, an on-current of the tunneling transistor is substantially improved as compared to that of a conventional tunneling transistor. In another embodiment, a tunneling transistor includes a heterostructure that reduces a turn-on voltage of the tunneling transistor. |
| FILED | Friday, April 17, 2009 |
| APPL NO | 12/425962 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384129 | Kub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Francis J. Kub (Arnold, Maryland); Karl D. Hobart (Upper Marlboro, Maryland); Charles R. Eddy, Jr. (Columbia, Maryland); Michael A Mastro (Fairfax, Virginia); Travis Anderson (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Francis J. Kub (Arnold, Maryland); Karl D. Hobart (Upper Marlboro, Maryland); Charles R. Eddy, Jr. (Columbia, Maryland); Michael A Mastro (Fairfax, Virginia); Travis Anderson (Alexandria, Virginia) |
| ABSTRACT | High electron mobility transistors and fabrication processes are presented in which a barrier material layer of uniform thickness is provided for threshold voltage control under an enhanced channel charge inducing material layer (ECCIML) in source and drain regions with the ECCIML layer removed in the gate region. |
| FILED | Friday, June 25, 2010 |
| APPL NO | 12/823210 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384169 | Langebrake et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Langebrake (Seminole, Florida); Shinzo Onishi (Seminole, Florida); Scott Samson (Safety Harbor, Florida); Raj Popuri (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Lawrence Langebrake (Seminole, Florida); Shinzo Onishi (Seminole, Florida); Scott Samson (Safety Harbor, Florida); Raj Popuri (Tampa, Florida) |
| ABSTRACT | The present invention provides a DC high voltage converter having an oscillator driver, main switch array and topological enhanced capacitors. The switch array utilizes MEM cantilevers and topological capacitors for charge storages for the generation of a high voltage output from a low voltage input. |
| FILED | Wednesday, November 30, 2011 |
| APPL NO | 13/307549 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/418 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384182 | Mazzola et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael S. Mazzola (Starkville, Mississippi); Lin Cheng (Starkville, Mississippi) |
| ASSIGNEE(S) | Power Integrations, Inc. (San Jose, California) |
| INVENTOR(S) | Michael S. Mazzola (Starkville, Mississippi); Lin Cheng (Starkville, Mississippi) |
| ABSTRACT | A junction barrier Schottky (JBS) rectifier device and a method of making the device are described. The device comprises an epitaxially grown first n-type drift layer and p-type regions forming p+-n junctions and self-planarizing epitaxially over-grown second n-type drift regions between and, optionally, on top of the p-type regions. The device may include an edge termination structure such as an exposed or buried P+ guard ring, a regrown or implanted junction termination extension (JTE) region, or a “deep” mesa etched down to the substrate. The Schottky contact to the second n-type drift region and the ohmic contact to the p-type region together serve as an anode. The cathode can be formed by ohmic contact to the n-type region on the backside of the wafer. The devices can be used in monolithic digital, analog, and microwave integrated circuits. |
| FILED | Thursday, June 26, 2008 |
| APPL NO | 12/146580 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/475 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384409 | Kummel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew C. Kummel (San Diego, California); Dengliang Yang (Union City, California); William C. Trogler (Del Mar, California); Thomas Gredig (Huntington Beach, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andrew C. Kummel (San Diego, California); Dengliang Yang (Union City, California); William C. Trogler (Del Mar, California); Thomas Gredig (Huntington Beach, California) |
| ABSTRACT | An embodiment of the invention is an organic thin film transistor chemical sensor. The sensor includes a substrate. A gate electrode is isolated from drain and source electrodes by gate dielectric. An organic ultra-thin semiconductor thin film is arranged with respect to the gate, source and drain electrodes to act as a conduction channel in response to appropriate gate, source and drain potentials. The organic ultra-thin film is permeable to a chemical analyte of interest and consists of one or a few atomic or molecular monolayers of material. An example sensor array system includes a plurality of sensors of the invention. In a preferred embodiment, a sensor chip having a plurality of sensors is mounted in a socket, for example by wire bonding. The socket provides thermal and electrical interference isolation for the sensor chip from associated sensing circuitry that is mounted on a common substrate, such as a PCB (printed circuit board). A method of operating an organic thin film transistor chemical sensor exposes the sensor to a suspected analyte. A low duty cycle voltage pulse train is applied to the gate electrode to reduce baseline drift while sensing for a conduction channel change. |
| FILED | Monday, May 05, 2008 |
| APPL NO | 12/597976 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/762.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384418 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Weiguang Lu (San Jose, California); Matthew P. Baker (San Francisco, California) |
| ASSIGNEE(S) | Xilinx, Inc. (San Jose, California) |
| INVENTOR(S) | Weiguang Lu (San Jose, California); Matthew P. Baker (San Francisco, California) |
| ABSTRACT | A system for protecting an input/output (I/O) pin of an integrated circuit device (IC) from single event transients is disclosed. The system includes a first delay circuit that is configured to delay a clock signal from the clock source by a first predetermined amount of time, and a second delay circuit that is configured to delay the clock signal by a second predetermined amount of time. The system further includes a first register that is clocked by the clock signal, a second register that is clocked by the clock signal delayed by the first predetermined amount of time, and a third register that is clocked by the clock signal delayed by the second predetermined amount of time. The system also includes voter circuits, where each voter circuit is configured to receive a first data signal from an output of the first register, a second data signal from an output of the second register, and a third data signal from an output of the third register. |
| FILED | Thursday, March 24, 2011 |
| APPL NO | 13/071453 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Electronic digital logic circuitry 326/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384588 | Hansen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles T. Hansen (Palos Verdes Estates, California) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Charles T. Hansen (Palos Verdes Estates, California) |
| ABSTRACT | A method for estimating a target angle of a wideband signal received on an electronically steered antenna array includes: generating spatial frequency data from the received wideband signal; stabilizing the spatial frequency data to a beam steering direction; compressing the stabilized spatial frequency data to a plurality of frequency range bins; calculating a monopulse discriminant from the stabilized spatial frequency data; and calculating the target angle using the monopulse discriminant. |
| FILED | Tuesday, October 26, 2010 |
| APPL NO | 12/925668 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384613 | Murphey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas W. Murphey (Albuquerque, New Mexico); Joseph N. Footdale (Albuquerque, New Mexico) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Thomas W. Murphey (Albuquerque, New Mexico); Joseph N. Footdale (Albuquerque, New Mexico) |
| ABSTRACT | A non-planar surface support structure that is compatible with deployable thin shell reflector segments. The structure is composed of multiple four strut closed loops connected to compliant hinges at the nodes to create an effective surface. The deployed surface shape is determined by the strut lengths (L) and the node locations and the packaged compatibility constraint in which L1+L3−L2−L4 approximately equals zero. Each of the compliant hinges have degrees of freedom such that the compact configuration of the support structure is obtained by the translation of two opposite nodes of each loop upwards and the remaining two nodes downwards in a continuous process until all struts are approximately parallel and tightly bundled and the hinges lock out all degrees of freedom in the deployed configuration. |
| FILED | Tuesday, September 08, 2009 |
| APPL NO | 12/555034 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/880 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385067 | Arvelo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amilcar Arvelo (Poughkeepsie, New York); Jason R. Eagle (Kasson, Minnesota); Eric A. Eckberg (Rochester, Minnesota); Gary F. Goth (Pleasant Valley, New York); Katie L. Pizzolato (Austin, Texas); Scott A. Shurson (Mantorville, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Amilcar Arvelo (Poughkeepsie, New York); Jason R. Eagle (Kasson, Minnesota); Eric A. Eckberg (Rochester, Minnesota); Gary F. Goth (Pleasant Valley, New York); Katie L. Pizzolato (Austin, Texas); Scott A. Shurson (Mantorville, Minnesota) |
| ABSTRACT | A system to remove heat from an in-line memory module and/or circuit board may include a cold-rail to engage each end of an in-line memory module adjacent to where the in-line memory module is attachable to a circuit board, the cold-rail to remove heat from the in-line memory module. The system may also include a cold-plate connected to the cold-rail with the circuit board between the cold-plate and the cold-rail, the cold-plate to remove heat from the circuit board. |
| FILED | Thursday, November 11, 2010 |
| APPL NO | 12/944680 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/699 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385378 | Vurgaftman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Igor Vurgaftman (Odenton, Maryland); Jerry R. Meyer (Catonsville, Maryland); Chadwick Lawrence Canedy (Washington, District of Columbia); William W. Bewley (Falls Church, Virginia); James R. Lindle (Bowie, Maryland); Chul Soo Kim (Springfield, Virginia); Mijin Kim (Springfield, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Igor Vurgaftman (Odenton, Maryland); Jerry R. Meyer (Catonsville, Maryland); Chadwick Lawrence Canedy (Washington, District of Columbia); William W. Bewley (Falls Church, Virginia); James R. Lindle (Bowie, Maryland); Chul Soo Kim (Springfield, Virginia); Mijin Kim (Springfield, Virginia) |
| ABSTRACT | A gain medium and an interband cascade laser, having the gain medium are presented. The gain medium can have one or both of the following features: (1) the thicknesses of the one or more hole quantum wells in the hole injector region are reduced commensurate with the thickness of the active hole quantum well in the active quantum well region, so as to place the valence band maximum in the hole injector region at least about 100 meV lower than the valence band maximum in the active hole quantum well; and (2) the thickness of the last well of the electron injector region is between 85 and 110% of the thickness of the first active electron quantum well in the active gain region of the next stage of the medium. A laser incorporating a gain medium in accordance with the present invention can emit in the mid-IR range from about 2.5 to 8 μm at high temperatures with room-temperature continuous wave operation to wavelengths of at least 4.6 μm, threshold current density of about 400 A/cm2 and threshold power density of about 900 W/cm2. |
| FILED | Monday, September 10, 2012 |
| APPL NO | 13/608115 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/45.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385382 | Goldberg |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lew Goldberg (Fairfax, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Lew Goldberg (Fairfax, Virginia) |
| ABSTRACT | A compact solid state laser that generates multiple wavelengths and multiple beams that are parallel, i.e., bore-sighted relative to each other, is disclosed. Each of the multiple laser beams can be at a different wavelength, pulse energy, pulse length, repetition rate and average power. Each of the laser beams can be turned on or off independently. The laser is comprised of an optically segmented gain section, common laser resonator with common surface segmented cavity mirrors, optically segmented pump laser, and different intra-cavity elements in each laser segment. |
| FILED | Tuesday, March 22, 2011 |
| APPL NO | 13/053422 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/97 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385547 | Rohde et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gustavo K. Rohde (Pittsburgh, Pennsylvania); Jonathan M. Nichols (Crofton, Maryland); Frank Bucholtz (Crofton, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gustavo K. Rohde (Pittsburgh, Pennsylvania); Jonathan M. Nichols (Crofton, Maryland); Frank Bucholtz (Crofton, Maryland) |
| ABSTRACT | A system and method for encoding zero and one bits for transmission, including generating a first signal from a non-linear chaotic system to represent the one bit, with the signal's embedded vectors being within the non-linear system's attractor set, and generating a second signal from the non-linear system to represent the zero bit, with the signal's embedded vectors being outside the non-linear system's attractor set. The second signal encoding the zero bit can be generated by adding together two chaotic signals arising from the non-linear system initialized with different initial conditions, and weighting the second signal to have approximately the same energy as the first signal. One suitable chaotic systems is a Lorenz system. Systems and methods for decoding a transmitted stream of signals compare a detection statistic of the received stream of signals to a threshold value that depends on the chaotic system. |
| FILED | Monday, September 10, 2007 |
| APPL NO | 11/853012 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Cryptography 380/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385548 | Kanter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory S. Kanter (Chicago, Illinois); Shawn Wang (Evanston, Illinois) |
| ASSIGNEE(S) | Nucrypt LLC (Evanston, Illinois) |
| INVENTOR(S) | Gregory S. Kanter (Chicago, Illinois); Shawn Wang (Evanston, Illinois) |
| ABSTRACT | Apparatus and method for producing quantum entangled signal and idler photon pairs is provided. The apparatus makes use of a nonlinear optical fiber to generate the entangled photons. The use of an external broad band light source for alignment of any downstream measurement apparatuses is disclosed. One or more polarized output signals can be generated at both the signal and idler wavelengths using the alignment source, allowing the downstream measurement apparatuses to be aligned using classical light. Multiple signal and idler wavelengths can be generated and aligned using such a system. |
| FILED | Thursday, February 18, 2010 |
| APPL NO | 12/708184 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Cryptography 380/263 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385560 | Solbeck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jason Solbeck (Canaan, New Hampshire); Matt Maher (West Lebanon, New Hampshire); Christopher Deitrich (Hartland, Vermont); Laura Ray (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Solbeck (Canaan, New Hampshire); Matt Maher (West Lebanon, New Hampshire); Christopher Deitrich (Hartland, Vermont); Laura Ray (Hanover, New Hampshire) |
| ABSTRACT | A noise canceling and communication system includes an in-ear device adapted to fit in the ear canal of a device user. A passive noise reduction element reduces external noise entering the ear canal. An external microphone senses an external acoustic signal outside the ear canal. An internal microphone senses an internal acoustic signal proximal to the tympanic membrane. One or more internal sound generators produce a noise cancellation signal and an acoustic communication signal, both directed towards the tympanic membrane. A probe tube shapes an acoustic response between the internal sound generator and the internal microphone to be relatively constant over a wide audio frequency band. An electronics module is located externally of the ear canal and in communication with the in-ear device for processing the microphone signals using a hybrid feed forward and feedback active noise reduction algorithm to produce the noise cancellation signal. |
| FILED | Wednesday, September 24, 2008 |
| APPL NO | 12/236657 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Electrical audio signal processing systems and devices 381/71.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385630 | Sizintsev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mikhail Sizintsev (Thornhill, Canada); Sujit Kuthirummal (Jersey City, New Jersey); Rakesh Kumar (Princeton Junction, New Jersey); Supun Samarasekera (Princeton, New Jersey); Harpreet Singh Sawhney (West Windsor, New Jersey) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Mikhail Sizintsev (Thornhill, Canada); Sujit Kuthirummal (Jersey City, New Jersey); Rakesh Kumar (Princeton Junction, New Jersey); Supun Samarasekera (Princeton, New Jersey); Harpreet Singh Sawhney (West Windsor, New Jersey) |
| ABSTRACT | The present invention is a system and a method for processing stereo images utilizing a real time, robust, and accurate stereo matching system and method based on a coarse-to-fine architecture. At each image pyramid level, non-centered windows for matching and adaptive upsampling of coarse-level disparities are performed to generate estimated disparity maps using the ACTF approach. In order to minimize propagation of disparity errors from coarser to finer levels, the present invention performs an iterative optimization, at each level, that minimizes a cost function to generate smooth disparity maps with crisp occlusion boundaries. |
| FILED | Wednesday, December 29, 2010 |
| APPL NO | 12/980590 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385685 | Bedros et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Saad J. Bedros (West St. Paul, Minnesota); Jana Trojanova (Prague, Czech Republic) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Saad J. Bedros (West St. Paul, Minnesota); Jana Trojanova (Prague, Czech Republic) |
| ABSTRACT | A system and method include decomposing via a computer an ocular region into several filtered images of different orientation and scale, using the computer to combine the decomposed images for each scale, using a computer executed classifier for each scale, matching across different quality images, and using a computer, constructing a matching score by combining the scale scores using adaptively weighted sum for each scale. |
| FILED | Wednesday, June 08, 2011 |
| APPL NO | 13/155548 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/284 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385693 | Schmidt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Holger Schmidt (Capitola, California); Aaron Roe Hawkins (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Holger Schmidt (Capitola, California); Aaron Roe Hawkins (Provo, Utah) |
| ABSTRACT | An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate. |
| FILED | Thursday, June 16, 2011 |
| APPL NO | 13/161748 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386095 | Fitzpatrick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Fitzpatrick (Rio Rancho, New Mexico) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | David Fitzpatrick (Rio Rancho, New Mexico) |
| ABSTRACT | Methods and systems are provided for using a measurement of only one axis of a three-axis magnetometer to perform at least one corrective action on an unmanned aerial vehicle (“UAV”). An exemplary embodiment comprises (i) receiving from a three-axis magnetometer a measurement representative of an attitude of a UAV, wherein the measurement is of only one axis of the magnetometer, (ii) comparing the measurement to an allowable range of attitudes, (iii) determining that the measurement is not within the allowable range of attitudes, and (iv) performing at least one corrective action on the UAV. |
| FILED | Thursday, April 02, 2009 |
| APPL NO | 12/417380 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386175 | Limbaugh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Douglas V. Limbaugh (Glendale, Arizona); David H. Barnhard (Lilburn, Georgia); Thomas H. Rychener (Phoenix, Arizona) |
| ASSIGNEE(S) | Kutta Technologies, Inc. (Phoenix, Arizona) |
| INVENTOR(S) | Douglas V. Limbaugh (Glendale, Arizona); David H. Barnhard (Lilburn, Georgia); Thomas H. Rychener (Phoenix, Arizona) |
| ABSTRACT | An unmanned aerial system (UAS) position reporting system. Implementations may include an air traffic control reporting system (ATC-RS) coupled with a ground control station (GCS) of an unmanned aerial system where the ATC-RS includes an automatic dependent surveillance broadcast (ADS-B) and a traffic information services broadcast (TIS-B) transceiver and one or more telecommunications modems. The ATC-RS may be adapted to receive position data of the UAS in an airspace from the GCS and communicate the position of the UAS in the airspace to a civilian air traffic control center (ATC) or to a military command and control (C2) communication center through an ADS-B signal or through a TIS-B signal through the ADS-B and TIS-B transceiver. The ATC-RS may also be adapted to display the position of the UAS in the airspace on one or more display screens coupled with the ATC-RS. |
| FILED | Thursday, February 12, 2009 |
| APPL NO | 12/370407 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/485 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386602 | Carey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James E. Carey (Rochester, Minnesota); Matthew W. Markland (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | James E. Carey (Rochester, Minnesota); Matthew W. Markland (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota) |
| ABSTRACT | Methods, systems and products are provided relevant alert delivery including assigning by an event analyzer each received event to an events pool; determining by the event analyzer in dependence upon event analysis rules and the events assigned to the events pool whether to suppress one or more of the events; identifying by the event analyzer in dependence upon event analysis rules and the events assigned to the events pool one or more alerts; sending by the event analyzer to an alert analyzer all the alerts identified by the event analyzer; assigning by the alert analyzer the identified alerts to an alerts pool; determining by the alert analyzer in dependence upon alert analysis rules and the alerts in the alert pool whether to suppress any alerts; and transmitting the unsuppressed alerts to one or more components of the distributed processing system. |
| FILED | Tuesday, November 02, 2010 |
| APPL NO | 12/938084 |
| ART UNIT | 2448 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/224 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386753 | Eisen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susan E. Eisen (Round Rock, Texas); Dung Q. Nguyen (Austin, Texas); Balaram Sinharoy (Poughkeepsie, New York); Benjamin W. Stolt (Austin, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Susan E. Eisen (Round Rock, Texas); Dung Q. Nguyen (Austin, Texas); Balaram Sinharoy (Poughkeepsie, New York); Benjamin W. Stolt (Austin, Texas) |
| ABSTRACT | A mechanism is provided for thread completion arbitration. The mechanism comprises executing more than two threads of instructions simultaneously in the processor, selecting a first thread from a first subset of threads, in the more than two threads, for completion of execution within the processor, and selecting a second thread from a second subset of threads, in the more than two threads, for completion of execution within the processor. The mechanism further comprises completing execution of the first and second threads by committing results of the execution of the first and second threads to a storage device associated with the processor. At least one of the first subset of threads or the second subset of threads comprise two or more threads from the more than two threads. The first subset of threads and second subset of threads have different threads from one another. |
| FILED | Tuesday, April 14, 2009 |
| APPL NO | 12/423561 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386801 | Devadas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Srinivas Devadas (Lexington, Massachusetts); Blaise Gassend (San Carlos, California) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Srinivas Devadas (Lexington, Massachusetts); Blaise Gassend (San Carlos, California) |
| ABSTRACT | A group of devices are fabricated based on a common design, each device having a corresponding plurality of measurable characteristics that is unique in the group to that device, each device having a measurement module for measuring the measurable characteristics. Authentication of one of the group of devices is enabled by selective measurement of one or more of the plurality of measurable characteristics of the device. |
| FILED | Thursday, March 03, 2011 |
| APPL NO | 13/039391 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386822 | Arimilli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas) |
| ABSTRACT | A wake-and-go mechanism is provided for a data processing system. The wake-and-go mechanism recognizes a programming idiom, specialized instruction, operating system call, or application programming interface call that indicates that a thread is waiting for an event. The wake-and-go mechanism updates a wake-and-go array with a target address, expected data value, and comparison type associated with the event. The thread then goes to sleep until the event occurs. The wake-and-go array may be a content addressable memory (CAM). When a transaction appears on the symmetric multiprocessing (SMP) fabric that modifies the value at a target address in the CAM, logic associated with the CAM performs a comparison based on the data value being written, expected data value, and comparison type. |
| FILED | Friday, February 01, 2008 |
| APPL NO | 12/024540 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08387065 | Arimilli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ravi K. Arimilli (Austin, Texas); Ronald N. Kalla (Round Rock, Texas); Balaram Sinharoy (Poughkeepsie, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ravi K. Arimilli (Austin, Texas); Ronald N. Kalla (Round Rock, Texas); Balaram Sinharoy (Poughkeepsie, New York) |
| ABSTRACT | A method and a data processing system by which population count (popcount) operations are efficiently performed without incurring the latency and loss of critical processing cycles and bandwidth of real time processing. The method comprises: identifying data to be stored to memory for which a popcount may need to be determined; speculatively performing a popcount operation on the data as a background process of the processor while the data is being stored to memory; storing the data to a first memory location; and storing a value of the popcount generated by the popcount operation within a second memory location. The method further comprises: determining a size of data; determining a granular level at which the popcount operation on the data will be performed; and reserving a size of said second memory location that is sufficiently large to hold the value of the popcount. |
| FILED | Thursday, April 16, 2009 |
| APPL NO | 12/425343 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08387115 | Park |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joon S. Park (Jamesville, New York) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Joon S. Park (Jamesville, New York) |
| ABSTRACT | A method of dynamically assigning a role to a user in a distributed computing environment can comprise the steps of: defining one or more roles and their respective threshold trust values; defining one or more attributes and their respective weight coefficients; determining current values of the attributes for the user; calculating a current level of trust for the user, based on the attribute values and the weight coefficients; and assigning a role to the user based on the current level of trust and the threshold values. |
| FILED | Wednesday, February 18, 2009 |
| APPL NO | 12/388252 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Information security 726/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE44032 | Ricks-Laskoski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Holly L. Ricks-Laskoski (Springfield, Virginia); Arthur W Snow (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Holly L. Ricks-Laskoski (Springfield, Virginia); Arthur W Snow (Alexandria, Virginia) |
| ABSTRACT | Disclosed is a new ionic liquid monomer salt and methods of is synthesis and polymerization. The ionic liquid monomer salt is prepared by mixing equimolar amounts of an amine, such as tris[2-(2-methoxyethoxy)-ethyl]amine and an acid functionalized polymerizable monomer, such as 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), which is stirred at ambient temperature until salt formation is complete. Also disclosed is a new ionic liquid polymer salts and method for making the same. The synthesis of AMPS 2-acrylamido-2-methyl-1-propanesulfonic acid-ammonium salt polymer is accomplished by adding 2,2′-azobisisobutyronitrile (AIBN) to the ionic liquid monomer salt and heating the homogeneous melt at 70° C. for 18 hr. |
| FILED | Wednesday, January 05, 2011 |
| APPL NO | 12/984816 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 562/114 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 08381739 | Gonda |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Igor Gonda (Hayward, California) |
| ASSIGNEE(S) | Aradigm Corporation (Hayward, California) |
| INVENTOR(S) | Igor Gonda (Hayward, California) |
| ABSTRACT | The invention relates generally to a system and method for treating conditions responsive to nicotine therapy. More specifically, the invention relates to pulmonary administration of a nicotine containing formulation to effect smoking cessation. |
| FILED | Wednesday, September 10, 2008 |
| APPL NO | 12/208176 |
| ART UNIT | 1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Tobacco 131/270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382896 | Hansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carl L. Hansen (Pasadena, California); Stephen R. Quake (San Marino, California); James M. Berger (Kensington, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carl L. Hansen (Pasadena, California); Stephen R. Quake (San Marino, California); James M. Berger (Kensington, California) |
| ABSTRACT | High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels. |
| FILED | Monday, January 29, 2007 |
| APPL NO | 11/668263 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/68 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383086 | Brenner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles M. Brenner (Lyme, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Charles M. Brenner (Lyme, New Hampshire) |
| ABSTRACT | The present invention relates to isolated nicotinamide riboside kinase (Nrk) nucleic acid sequences, vectors and cultured cells containing the same, and Nrk polypeptides encoded thereby. Methods for identifying individuals or tumors susceptible to nicotinamide riboside-related prodrug treatment and methods for treating cancer by administering an Nrk nucleic acid sequence or polypeptide in combination with a nicotinamide riboside-related prodrug are also provided. The present invention further provides screening methods for isolating a nicotinamide riboside-related prodrug and identifying a natural source of nicotinamide riboside. |
| FILED | Thursday, April 12, 2012 |
| APPL NO | 13/445289 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/48 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383092 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce P. Lee (Madison, Wisconsin); Laura Vollenweider (Middleton, Wisconsin); John L. Murphy (Madison, Wisconsin); Fangmin Xu (Middleton, Wisconsin); Jeffrey L. Dalsin (Madison, Wisconsin); Jeanne Virosco (Madison, Wisconsin); William Lew (Mendota Heights, Minnesota); Jed White (Madison, Wisconsin) |
| ASSIGNEE(S) | KNC NER Acquisition Sub, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Bruce P. Lee (Madison, Wisconsin); Laura Vollenweider (Middleton, Wisconsin); John L. Murphy (Madison, Wisconsin); Fangmin Xu (Middleton, Wisconsin); Jeffrey L. Dalsin (Madison, Wisconsin); Jeanne Virosco (Madison, Wisconsin); William Lew (Mendota Heights, Minnesota); Jed White (Madison, Wisconsin) |
| ABSTRACT | The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons. |
| FILED | Monday, September 28, 2009 |
| APPL NO | 12/568527 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08383096 — Cancer immunotherapy with a viral antigen-defined, immunomodulator-secreting cell vaccine
| US 08383096 | Ambinder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard F. Ambinder (Lutherville, Maryland); Yiping Yang (Chapel Hill, North Carolina); Ivan M. Borrello (Baltimore, Maryland); Hyam I. Levitsky (Owing Hills, Maryland) |
| ASSIGNEE(S) | Johns Hopkins University School of Medicine (Baltimore, Maryland) |
| INVENTOR(S) | Richard F. Ambinder (Lutherville, Maryland); Yiping Yang (Chapel Hill, North Carolina); Ivan M. Borrello (Baltimore, Maryland); Hyam I. Levitsky (Owing Hills, Maryland) |
| ABSTRACT | A human cell line, which lacks major histocompatibility class I (MHC-I) antigens and major histocompatibility class II (MHC-II) antigens and which has been modified to comprise and express (i) a nucleotide sequence encoding an immunomodulator and (ii) a nucleotide sequence encoding a viral antigen, and a method of inducing or stimulating an immune response in a human to a viral-associated disease or cancer comprising administering to the human (i) the aforementioned human cell line in an amount sufficient to induce or stimulate an immune response to the viral associated disease or cancer, (ii) a human cell line, which lacks MHC-I and MHC-11 antigens and which has been modified to comprise and express a nucleotide sequence encoding an immunomodulator, and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral-associated disease or cancer, or (iii) an immunomodulator and a human cell line, which lacks MHC-I and MHC-II antigens and which has been modified to comprise and express a nucleotide sequence encoding an antigen of EBV, simultaneously or sequentially in either order, by the same or different routes, in amounts sufficient to induce or stimulate an immune response to the viral associated disease or cancer. |
| FILED | Thursday, April 08, 2010 |
| APPL NO | 12/756364 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383098 | Trapp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce Trapp (Bentleyville, Ohio); Robert Miller (Cleveland Heights, Ohio) |
| ASSIGNEE(S) | Case Western REserve University (Cleveland, Ohio) |
| INVENTOR(S) | Bruce Trapp (Bentleyville, Ohio); Robert Miller (Cleveland Heights, Ohio) |
| ABSTRACT | An isolated multipotent neural stem cells has a phenotype identified by expression of the protein β-tubulin IV and Olig2 and the absence of the proteins NG2, PLP, and GFAP. |
| FILED | Monday, August 30, 2010 |
| APPL NO | 12/871743 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383099 | Dudley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark E. Dudley (Washington, District of Columbia); Steven A. Rosenberg (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Mark E. Dudley (Washington, District of Columbia); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | The invention provides a method of promoting regression of a cancer in a mammal comprising (i) culturing autologous T cells; (ii) expanding the cultured T cells; (iii) administering to the mammal nonmyeloablative lymphodepleting chemotherapy; and (iv) after administering nonmyeloablative lymphodepleting chemotherapy, administering to the mammal the expanded T cells, wherein the T cells administered to the mammal are about 19 to about 35 days old and have not been screened for specific tumor reactivity, whereupon the regression of the cancer in the mammal is promoted. |
| FILED | Thursday, August 26, 2010 |
| APPL NO | 12/869390 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383113 | Acton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Acton (Quakertown, Pennsylvania); Zhiqiang An (Ambler, Pennsylvania); Andrew J. Bett (Lansdale, Pennsylvania); Robert Breese (Quakertown, Pennsylvania); Lei Chang (Westmont, Illinois); Elizabeth Chen Dodson (Souderton, Pennsylvania); Gene Kinney (Collegeville, Pennsylvania); William Klein (Winetka, Illinois); Mary P. Lambert (Glenview, Illinois); Xiaoping Liang (Collegeville, Pennsylvania); Paul Shughrue (West Chester, Pennsylvania); William R. Strohl (Bridgewater, New Jersey); Kristen Viola (Chicago, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Merck Sharp and Dohme Corp. (Rahway, New Jersey) |
| INVENTOR(S) | Paul Acton (Quakertown, Pennsylvania); Zhiqiang An (Ambler, Pennsylvania); Andrew J. Bett (Lansdale, Pennsylvania); Robert Breese (Quakertown, Pennsylvania); Lei Chang (Westmont, Illinois); Elizabeth Chen Dodson (Souderton, Pennsylvania); Gene Kinney (Collegeville, Pennsylvania); William Klein (Winetka, Illinois); Mary P. Lambert (Glenview, Illinois); Xiaoping Liang (Collegeville, Pennsylvania); Paul Shughrue (West Chester, Pennsylvania); William R. Strohl (Bridgewater, New Jersey); Kristen Viola (Chicago, Illinois) |
| ABSTRACT | The present invention relates to antibodies that differentially recognize multi-dimensional conformations of Aβ-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid β 1-42. |
| FILED | Wednesday, February 08, 2012 |
| APPL NO | 13/368742 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383116 | Fabene et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paolo Francesco Fabene (Iocalita' Santa Lucia ai Monti, Italy); Eugene C. Butcher (Portola Valley, California); Gabriela Constantin (San Floriano, Italy) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Paolo Francesco Fabene (Iocalita' Santa Lucia ai Monti, Italy); Eugene C. Butcher (Portola Valley, California); Gabriela Constantin (San Floriano, Italy) |
| ABSTRACT | Methods are provided for the prevention and treatment of seizures and epilepsy. It is shown herein that leukocyte recruitment plays a key role in the pathogenesis of epilepsy. Treatment with an agent that inhibits leukocyte recruitment has therapeutic and preventative effects in blocking recurrent seizures and epilepsy. |
| FILED | Tuesday, October 13, 2009 |
| APPL NO | 12/587879 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/139.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383132 | Horwitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marcus A. Horwitz (Los Angeles, California); Michael Tullius (Encino, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Marcus A. Horwitz (Los Angeles, California); Michael Tullius (Encino, California) |
| ABSTRACT | Immunogenic compositions comprising recombinant intracellular pathogens that have been transformed to express recombinant immunogenic antigens of the same or other intracellular pathogens and immunostimulatory molecules are provided. Exemplary immunogenic compositions include, but are not limited to, recombinant BCG expressing Mycobacteria major extracellular proteins and immunostimulatory molecules. |
| FILED | Friday, January 07, 2011 |
| APPL NO | 12/986598 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/248.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383133 | Schneerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rachel Schneerson (Bethesda, Maryland); Joanna Kubler-Kielb (Bethesda, Maryland); Yimin Wu (Frederick, Maryland); Louis Miller (Cabin John, Maryland); Fathy D. Majadly (Frederick, Maryland); John B. Robbins (New York, New York) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Rachel Schneerson (Bethesda, Maryland); Joanna Kubler-Kielb (Bethesda, Maryland); Yimin Wu (Frederick, Maryland); Louis Miller (Cabin John, Maryland); Fathy D. Majadly (Frederick, Maryland); John B. Robbins (New York, New York) |
| ABSTRACT | Conjugates of ookinete surface protein Pfs25 are provided that are efficacious as vaccines against Plasmodium falciparum, the most severe form of malaria. Conjugates of ookinete surface protein Pvs25 for use as a vaccine against Plasmodium vivax are also provided. Methods for preparing the conjugates, which comprise the ookinete surface protein bound onto itself or onto another protein by a linking group, are also provided. |
| FILED | Monday, October 15, 2007 |
| APPL NO | 12/444963 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/272.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383136 | Kwon |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Glen S. Kwon (Waunakee, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Glen S. Kwon (Waunakee, Wisconsin) |
| ABSTRACT | The invention provides active agents, such as paclitaxel, rapamycin, or 17-AAG, encapsulated by safe poly(ethylene glycol)-block-poly(lactic acid) (“PEG-b-PLA”) micelles. The compositions provide effective solubilization of drug combinations, such as paclitaxel, rapamycin, and 17-AAG, as well as others described herein. A significant advantage of PEG-b-PLA as a carrier is that it is less toxic than Cremophor® EL or DMSO, which are used in currently known compositions. Additionally, PEG-b-PLA micelles are easier to handle than DMSO and they do not possess a foul odor, which is a problem with formulations currently in clinical trials. Accordingly, the invention provides stable and biocompatible drug formulations that improve bioavailability without causing toxicity. It was also found that larger doses of individual drugs in micelle formulations can be administered compared to non-micelle formulations. |
| FILED | Friday, July 06, 2012 |
| APPL NO | 13/543363 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383348 | Willis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas D. Willis (San Francisco, California); Paul Hardenbol (Los Altos, California); Maneesh Jain (Menlo Park, California); Viktor Stolc (Cupertino, California); Mostafa Ronaghi (Palo Alto, California); Ronald W. Davis (Palo Alto, California) |
| ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Thomas D. Willis (San Francisco, California); Paul Hardenbol (Los Altos, California); Maneesh Jain (Menlo Park, California); Viktor Stolc (Cupertino, California); Mostafa Ronaghi (Palo Alto, California); Ronald W. Davis (Palo Alto, California) |
| ABSTRACT | The invention is directed to novel methods of multiplexing nucleic acid reactions, including amplification, detection and genotyping. The invention relies on the use of precircle probes that are circularized in the presence of the corresponding target nucleic acids, cleaved, and then amplified. |
| FILED | Tuesday, August 09, 2011 |
| APPL NO | 13/206120 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383352 | Redei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eva E. Redei (Chicago, Illinois); Pradeep K. Shukla (Chicago, Illinois); Laura J. Sittig (Chicago, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Eva E. Redei (Chicago, Illinois); Pradeep K. Shukla (Chicago, Illinois); Laura J. Sittig (Chicago, Illinois) |
| ABSTRACT | The present invention provides methods, compositions, and systems for detecting in utero alcohol exposure by detecting expression level changes in certain biomarkers (e.g., in placental tissue). In certain embodiments, the biomarkers are selected from glucocorticoid receptor (GR), thyroid hormone receptor alpha (TRα), iodothyronine deiodinase III (Dio3) and G-protein α-subunit (Gsα). |
| FILED | Monday, June 07, 2010 |
| APPL NO | 12/795082 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383359 | Frucht et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David M. Frucht (Vienna, Virginia); Hui Fang (Germantown, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | David M. Frucht (Vienna, Virginia); Hui Fang (Germantown, Maryland) |
| ABSTRACT | It is disclosed herein that isolated lymphocytes, such as human B-cells and CD4+ T-cell can be used to determine an amount of lymphocyte-associated anthrax lethal toxin activity present. Methods of using isolated lymphocytes to identify anthrax therapeutic agents and to determine the efficacy of a potential anthrax therapeutic are disclosed. Methods are also provided for diagnosing and treating anthrax infections. |
| FILED | Friday, September 24, 2010 |
| APPL NO | 12/889955 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383360 | Van de Water et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
| ABSTRACT | The present invention provides diagnostic methods for determining the risk of developing an autism spectrum disorder (ASD) in a fetus or child by detecting in a biological sample from the mother antibodies that bind to one or more biomarkers selected from the group consisting of lactate dehydrogenase (LDH), guanine deaminase (GDA), collapsin response mediator protein 1 (CRMP1), stress-induced phosphoprotein 1 (STIP1), alpha subunit of the barbed-end actin binding protein Cap Z (CAPZA2), Y Box Binding Protein 1 (YBX1), eukaryotic translation and elongation factor 1A1 (EEF1A1), microtubule-associated protein Tau (MAPT), dihydropyrimidinase-like protein 2 (DPYSL2), dynamin 1-like protein (DNM1L), radixin (RDX), moesin (MSN), and ezrin (EZR). The invention further provides methods of preventing or reducing the risk of a fetus or child developing an ASD by administering to the mother an agent that blocks the binding of maternal antibodies to the one or more fetal biomarkers listed above or by removing from the mother antibodies that bind to the one or more fetal biomarkers. |
| FILED | Thursday, August 12, 2010 |
| APPL NO | 12/855558 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.920 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383370 | Tuschl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas Tuschl (Brooklyn, New York); Janos Ludwig (Bonn-Vewsberg, Germany); Yi Pei (Paoli, Pennsylvania); Carolina Lin (Durham, North Carolina) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Thomas Tuschl (Brooklyn, New York); Janos Ludwig (Bonn-Vewsberg, Germany); Yi Pei (Paoli, Pennsylvania); Carolina Lin (Durham, North Carolina) |
| ABSTRACT | The invention provides a novel truncated mutated T4 RNA ligase 2. In addition, methods are provided for ligating pre-adenlylated donor molecules to the 3′ hydroxyl group of RNA in the absence of ATP using the ligase. |
| FILED | Wednesday, January 30, 2008 |
| APPL NO | 12/525176 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383386 | Camire |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rodney M. Camire (Sicklerville, New Jersey) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Rodney M. Camire (Sicklerville, New Jersey) |
| ABSTRACT | Factor Xa variants and methods of use thereof are disclosed. |
| FILED | Wednesday, November 15, 2006 |
| APPL NO | 12/093783 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/212 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383400 | Satchell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karla J. F. Satchell (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Karla J. F. Satchell (Evanston, Illinois) |
| ABSTRACT | Disclosed are fusion proteins, polynucleotides that encode the disclosed fusion proteins, and methods for expressing and autoprocessing of the disclosed fusion proteins to obtain a target protein. The disclosed fusion proteins include an autoproteolytic cysteine protease fused to a heterologous polypeptide, which may be isolated as the target protein. Preferably, the protease activity of the cysteine protease is inducible. Suitable autoproteolytic cysteine proteases for the fusion proteins include the cysteine protease of the Vibrio cholerae RTX toxin. |
| FILED | Tuesday, July 31, 2012 |
| APPL NO | 13/563171 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383423 | Weiss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shimon Weiss (Los Angeles, California); James M. Tsay (Los Angeles, California); Fabien Pinaud (Los Angeles, California); Soren Doose (Bielefeld, Germany) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shimon Weiss (Los Angeles, California); James M. Tsay (Los Angeles, California); Fabien Pinaud (Los Angeles, California); Soren Doose (Bielefeld, Germany) |
| ABSTRACT | A peptide-coated nanoparticle that includes a nanocrystal surrounded by a graded shell that is composed of at least two different semiconductor molecules. At least one peptide is attached to the surface of the graded shell to render the nanoparticle biocompatible. The nanocrystal core and graded shell are optionally annealed with ultra violet radiation prior to and/or after attachment of the peptide(s). |
| FILED | Tuesday, March 29, 2011 |
| APPL NO | 13/074209 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/524 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383425 | Hsieh-Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Linda Hsieh-Wilson (San Marino, California); Nelly Khidekel (Pasadena, California); Hwan-Ching Tai (Pasadena, California); Sabine Arndt (Dortmund, Germany) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Linda Hsieh-Wilson (San Marino, California); Nelly Khidekel (Pasadena, California); Hwan-Ching Tai (Pasadena, California); Sabine Arndt (Dortmund, Germany) |
| ABSTRACT | The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with post-translational glycosylations. The methods can be used to detect O-GlcNAc posttranslational modifications on proteins on which such modifications were undetectable using other techniques. In one embodiment, the method exploits the ability of an engineered mutant of β-1,4-galactosyltransferase to selectively transfer an unnatural ketone functionality onto O-GlcNAc glycosylated proteins. Once transferred, the ketone moiety serves as a versatile handle for the attachment of biotin, thereby enabling detection of the modified protein. The approach permits the rapid visualization of proteins that are at the limits of detection using traditional methods. Further, the preferred embodiments can be used for detection of certain disease states, such as cancer, Alzheimer's disease, neurodegeneration, cardiovascular disease, and diabetes. |
| FILED | Thursday, October 21, 2010 |
| APPL NO | 12/909402 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383580 | Rui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liangyou Rui (Ann Arbor, Michigan); Yingjiang Zhou (Arlington, Massachusetts) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Liangyou Rui (Ann Arbor, Michigan); Yingjiang Zhou (Arlington, Massachusetts) |
| ABSTRACT | A method of treating an LCN13-related condition is provided comprising administering to a patient in need thereof a therapeutically effective amount of a lipocalin or a physiologically active fragment thereof. |
| FILED | Friday, June 10, 2011 |
| APPL NO | 13/157977 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383589 | Calvo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eric Calvo (Bethesda, Maryland); Osvaldo Marinotti (Aliso Viejo, California); Jose M. C. Ribeiro (Rockville, Maryland); Ivo M. Francischetti (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eric Calvo (Bethesda, Maryland); Osvaldo Marinotti (Aliso Viejo, California); Jose M. C. Ribeiro (Rockville, Maryland); Ivo M. Francischetti (Washington, District of Columbia) |
| ABSTRACT | The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed. |
| FILED | Monday, July 07, 2008 |
| APPL NO | 12/668177 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383599 | Hannon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory J. Hannon (Huntington, New York); Patrick J. Paddison (Seattle, Washington); Emily Bernstein (New York, New York); Amy Caudy (Toronto, Canada); Douglas S. Conklin (Niskayuna, New York); Scott Hammond (Harbor Pittsboro, North Carolina) |
| ASSIGNEE(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| INVENTOR(S) | Gregory J. Hannon (Huntington, New York); Patrick J. Paddison (Seattle, Washington); Emily Bernstein (New York, New York); Amy Caudy (Toronto, Canada); Douglas S. Conklin (Niskayuna, New York); Scott Hammond (Harbor Pittsboro, North Carolina) |
| ABSTRACT | The present invention provides methods for attenuating gene expression in a cell using gene-targeted double stranded RNA (dsRNA). The dsRNA contains a nucleotide sequence that hybridizes under physiologic conditions of the cell to the nucleotide sequence of at least a portion of the gene to be inhibited (the “target” gene). |
| FILED | Friday, May 16, 2008 |
| APPL NO | 12/152837 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383600 | Czech et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael P. Czech (Worcester, Massachusetts); Aimee Powelka (Framingham, Massachusetts); Adilson L. Guilherme (Shrewsbury, Massachusetts); Xiaoqing Tang (Lexington, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Michael P. Czech (Worcester, Massachusetts); Aimee Powelka (Framingham, Massachusetts); Adilson L. Guilherme (Shrewsbury, Massachusetts); Xiaoqing Tang (Lexington, Massachusetts) |
| ABSTRACT | Methods and compositions for modulating glucose transport are provided herein. |
| FILED | Thursday, February 26, 2009 |
| APPL NO | 12/393212 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383601 | Koch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Walter J. Koch (Broomall, Pennsylvania); Patrick Most (Philadelphia, Pennsylvania); Sven T. Pleger (Heidelberg, Germany); Joseph E. Rabinowitz (Elkins Park, Pennsylvania) |
| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Walter J. Koch (Broomall, Pennsylvania); Patrick Most (Philadelphia, Pennsylvania); Sven T. Pleger (Heidelberg, Germany); Joseph E. Rabinowitz (Elkins Park, Pennsylvania) |
| ABSTRACT | The invention provides nucleic acid segments, compositions and methods for the treatment of heart failure, vascular dysfunction, endothelial dysfunction, diabetes, [Ca2+]i regulation and NO synthase dysfunction. Adeno-associated and adenovirus are used as gene delivery vectors for the nucleic acid segments to product long term over-expression of S100A1, a small calcium sensing protein associated with the disclosed ailments and dysfunctions. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 12/447558 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383604 | Orkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stuart H. Orkin (Brookline, Massachusetts); Vijay G. Sankaran (Jamaica Plain, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Stuart H. Orkin (Brookline, Massachusetts); Vijay G. Sankaran (Jamaica Plain, Massachusetts) |
| ABSTRACT | The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies. |
| FILED | Monday, September 14, 2009 |
| APPL NO | 13/063524 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383636 | Clinch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Keith Clinch (Lower Hutt, New Zealand); Gary Brian Evans (Lower Hutt, New Zealand); Richard Frohlich (Vienna, Austria); Richard Hubert Furneaux (Wellington, New Zealand); Peter Michael Kelly (Wellington, New Zealand); Jennifer Mary Mason (Lower Hutt, New Zealand); Vern L. Schramm (New Rochelle, New York); Peter Charles Tyler (Wellington, New Zealand); Shivall Ashwah Ashwin Gulab (Wellington, New Zealand) |
| ASSIGNEE(S) | Industrial Research Limited (Lower Hutt, New Zealand); Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Keith Clinch (Lower Hutt, New Zealand); Gary Brian Evans (Lower Hutt, New Zealand); Richard Frohlich (Vienna, Austria); Richard Hubert Furneaux (Wellington, New Zealand); Peter Michael Kelly (Wellington, New Zealand); Jennifer Mary Mason (Lower Hutt, New Zealand); Vern L. Schramm (New Rochelle, New York); Peter Charles Tyler (Wellington, New Zealand); Shivall Ashwah Ashwin Gulab (Wellington, New Zealand) |
| ABSTRACT | The present invention relates to compounds of the general formula (I) which are inhibitors of 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds. |
| FILED | Friday, September 07, 2007 |
| APPL NO | 12/310597 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/265.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383653 | Schramm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vern L. Schramm (New Rochelle, New York); Anthony A. Sauve (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Vern L. Schramm (New Rochelle, New York); Anthony A. Sauve (Bronx, New York) |
| ABSTRACT | Compounds are disclosed which inhibit SIR2 base exchange more than deacetylation, thus enhancing SIR2 deacetylation activity. Methods of using the compounds for enhancing SIR2 deacetylation activity and increasing longevity of an organism are also disclosed. Methods for screening for compounds that enhance SIR2 deacetylation activity and increase longevity of an organism are additionally disclosed. |
| FILED | Wednesday, June 30, 2004 |
| APPL NO | 10/560676 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/346 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383656 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ching-Shih Chen (Upper Arlington, Ohio); Jih-Hwa Guh (Taipei, Taiwan) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ching-Shih Chen (Upper Arlington, Ohio); Jih-Hwa Guh (Taipei, Taiwan) |
| ABSTRACT | A method of inhibiting glycolysis in a subject by administering a pharmaceutical composition including a thiazolidinedione derivative to the subject is described. The thiazolidinedione derivatives are effective energy restriction mimetic agents, and can therefore be used to treat or prevent cancer in a subject, treat metabolic disorder, or increase the longevity of a subject. Various thiazolidinedione derivatives are also suitable for activating adenosine phosphate-activated protein kinase or inhibiting IL-6 expression. |
| FILED | Monday, October 11, 2010 |
| APPL NO | 12/901782 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/369 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383758 | Papisov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mikhail I. Papisov (Winchester, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mikhail I. Papisov (Winchester, Massachusetts) |
| ABSTRACT | The present invention relates to biodegradable biocompatible polyketals, methods for their preparation, and methods for treating animals by administration of biodegradable biocompatible polyketals. In one aspect, a method for forming the biodegradable biocompatible polyketals comprises combining a glycol-specific oxidizing agent with a polysaccharide to form an aldehyde intermediate, which is combined with a reducing agent to form the biodegradable biocompatible polyketal. The resultant biodegradable biocompatible polyketals can be chemically modified to incorporate additional hydrophilic moieties. A method for treating animals includes the administration of the biodegradable biocompatible polyketal in which biologically active compounds or diagnostic labels can be disposed. The present invention also relates to chiral polyketals, methods for their preparation, and methods for use in chromatographic applications, specifically in chiral separations. A method for forming the chiral polyketals comprises combining a glycol-specific oxidizing agent with a polysaccharide to form an aldehyde intermediate, which is combined with a suitable reagent to form the chiral polyketal. A method for use in chiral separations includes the incorporation of the chiral polyketals in the mobile phase during a chromatographic separation, or into chiral stationary phases such as gels. The present invention further relates to chiral polyketals as a source for chiral compounds, and methods for generating such chiral compounds. |
| FILED | Tuesday, April 26, 2011 |
| APPL NO | 13/093951 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383793 | Morris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephan W. Morris (Germantown, Tennessee); Qin Jiang (Memphis, Tennessee); Xiaoli Cui (Memphis, Tennessee); Liquan Xue (Cordova, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Stephan W. Morris (Germantown, Tennessee); Qin Jiang (Memphis, Tennessee); Xiaoli Cui (Memphis, Tennessee); Liquan Xue (Cordova, Tennessee) |
| ABSTRACT | Compositions and methods for the diagnosis and treatment of a cancer that is resistant to at least one anaplastic lymphoma kinase (ALK) kinase inhibitor are provided herein. The present invention is based on the discovery of mutations within ALK that confer resistance to at least one ALK kinase inhibitor. Polynucleotides and polypeptides having at least one ALK inhibitor resistance mutation are provided and find use in methods and compositions useful in the diagnosis, prognosis, and/or treatment of diseases associated with aberrant ALK activity, more particularly, those that are resistant to at least one ALK kinase inhibitors. Methods and compositions are also provided for the identification of agents that can inhibit the kinase activity and/or reduce the expression level of the ALK resistance mutants. |
| FILED | Thursday, April 15, 2010 |
| APPL NO | 12/761050 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383806 | Rameshwar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pranela Rameshwar (Maplewood, New Jersey) |
| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey) |
| INVENTOR(S) | Pranela Rameshwar (Maplewood, New Jersey) |
| ABSTRACT | The present invention discloses the cloning of a new cDNA, HGFIN, from stimulated bone marrow stromal cells that was retrieved with a probe specific for the neurokinin-1 (NK-1) receptor. The novel gene, HGFIN, encodes a protein receptor that is involved in the regulation of hematopoietic proliferation and differentiation. HGFIN is implicated in the treatment of hyperproliferative disorders, particularly bone and breast cancer, because it acts to suppress the proliferating cells. |
| FILED | Wednesday, April 13, 2011 |
| APPL NO | 13/085612 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383817 | Newman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amy Hauck Newman (Phoenix, Maryland); Mu-Fa Zou (Baltimore, Maryland); Jonathan L. Katz (Columbia, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Amy Hauck Newman (Phoenix, Maryland); Mu-Fa Zou (Baltimore, Maryland); Jonathan L. Katz (Columbia, Maryland) |
| ABSTRACT | Disclosed are benztropine analogs having the formula (I) in which Ar is a C6-C20 monocyclic aryl group or a C10-C20 bicyclic aryl group or a heteroaryl, heterocyclic, or arylheterocyclic group having 2 to 12 carbon atoms and one or more heteroatoms selected from the group consisting of N, O, S, P, and any combination thereof; m=1 to 5; n=1 to 3; and R1 to R4 are as described in the specification; or a pharmaceutically acceptable salt or solvate thereof; pharmaceutical compositions and use thereof, e.g., in treating mental disorders. |
| FILED | Thursday, August 24, 2006 |
| APPL NO | 12/063072 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384991 | Kieu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Khanh Kieu (Ithaca, New York); Frank W. Wise (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Khanh Kieu (Ithaca, New York); Frank W. Wise (Ithaca, New York) |
| ABSTRACT | A saturable absorber (SA) is constructed using a fiber taper embedded in a carbon nanotube/polymer composite. A fiber taper is made by heating and pulling a small part of standard optical fiber. At the taper's waist light is guided by the glass-air interface, with an evanescent field protruding out of the taper. Carbon nanotubes mixed with an appropriate polymer host material are then wrapped around the fiber taper to interact with the evanescent field. Saturable absorption is possible due to the unique optical properties of the carbon nanotubes. The device can be used in mode-locked lasers where it initiates and stabilizes the pulses circulating around the laser cavity. The SA can be used in various laser cavities, and can enable different pulse evolutions such as solitons, self-similar pulses and dissipative solitons. Other applications include but are not limited to optical switching, pulse cleanup and pulse compression. |
| FILED | Thursday, December 23, 2010 |
| APPL NO | 12/977657 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/337 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385624 | Charlot et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David J. Charlot (La Jolla, California); Randall S. Ingermanson (Battleground, Washington); Patrick M. McDonough (San Diego, California); Jeffrey H. Price (Rancho Santa Fe, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David J. Charlot (La Jolla, California); Randall S. Ingermanson (Battleground, Washington); Patrick M. McDonough (San Diego, California); Jeffrey H. Price (Rancho Santa Fe, California) |
| ABSTRACT | A method, system, and instrument for automatically measuring transient activity in cells uses image time sequences to identify transients in cells. Preferably, the transient activity is stimulated or provoked in synchronism with acquisition of the image time sequences. A cell mask is applied to each image of an image time sequence in order to localize the transient activity with respect to each cell. Localization enables cell-by-cell analysis of properties of the transient activity. |
| FILED | Wednesday, May 13, 2009 |
| APPL NO | 12/454217 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Image analysis 382/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386007 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Justin C. Williams (Cambridge, Wisconsin); Karl A. Sillay (Madison, Wisconsin); Jiwan Kim (Madison, Wisconsin); David Niemann (Madison, Wisconsin); Azam Ahmed (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Justin C. Williams (Cambridge, Wisconsin); Karl A. Sillay (Madison, Wisconsin); Jiwan Kim (Madison, Wisconsin); David Niemann (Madison, Wisconsin); Azam Ahmed (Madison, Wisconsin) |
| ABSTRACT | A thin-film microelectrode array tailored for long-term, minimally invasive cortical recording or stimulation and method are provided. The microelectrode array includes a flexible element that is movable between a first contracted configuration and a second expanded configuration. An array of contacts is provided on the flexible element. The contacts are engagable with a cortical surface with the flexible element in the expanded configuration. A link operatively connects the array of contacts to a control module. The link is capable of transmitting at least one of cortical recordings and cortical stimulation signals thereon. |
| FILED | Friday, November 21, 2008 |
| APPL NO | 12/275696 |
| ART UNIT | 3739 — Optics |
| CURRENT CPC | Surgery 6/378 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386014 | Ciaccio |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edward J. Ciaccio (Cherry Hill, New Jersey) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Edward J. Ciaccio (Cherry Hill, New Jersey) |
| ABSTRACT | In some embodiments, the disclosed subject matter provides a method of identifying the source of arrhythmia, e.g. reentrant ventricular tachycardia, in a patient. In other embodiments, the disclosed subject matter provides a method for treating or preventing reentrant ventricular tachycardia in a patient. In still other embodiments, the disclosed subject matter provides systems for identifying the location of a candidate ablation site in a patient. In some embodiments, the patient has suffered from a myocardial infarction or has undergone structural remodeling of the heart caused by, e.g., cardiac fibrosis or the presence of dense trebeculation, resulting in nonviable areas with border zones (BZ). |
| FILED | Monday, June 23, 2008 |
| APPL NO | 12/144310 |
| ART UNIT | 3777 — Optics |
| CURRENT CPC | Surgery 6/411 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386015 | Kamen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ali Kamen (Princeton, New Jersey); Fred S. Azar (Oakland, New Jersey); John V. Frangioni (Wayland, Massachusetts) |
| ASSIGNEE(S) | Siemens Aktiengesellschaft (München, Germany); Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | Ali Kamen (Princeton, New Jersey); Fred S. Azar (Oakland, New Jersey); John V. Frangioni (Wayland, Massachusetts) |
| ABSTRACT | Macroscopic imaging data, such as from a CT, MR, PET, or SPECT scanner, is obtained. Microscopic imaging data of at least a portion of the same tissue is obtained. To align the microscopic imaging data with the macroscopic imaging data, intermediate data is also obtained. For example, photographic data is acquired at an intermediary stage of a process of preparing tissue for microscopic scan. The macroscopic and microscopic data are registered to the intermediary photographic data. Once registered to the intermediary data, the spatial relationship between the macroscopic and microscopic data is known and may be used for imaging or quantification. |
| FILED | Friday, October 23, 2009 |
| APPL NO | 12/604504 |
| ART UNIT | 3737 — Optics |
| CURRENT CPC | Surgery 6/411 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08381849 | Sastry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ann M. Sastry (Ann Arbor, Michigan); Kimberly A. Cook-Chennault (Princton Junction, New Jersey); Chia W. Wang (Ann Arbor, Michigan); Fabio Albano (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Ann M. Sastry (Ann Arbor, Michigan); Kimberly A. Cook-Chennault (Princton Junction, New Jersey); Chia W. Wang (Ann Arbor, Michigan); Fabio Albano (Ann Arbor, Michigan) |
| ABSTRACT | A hybrid energy storage system suitable for use in a vehicle having an electrified drivetrain includes a first energy storage module and a second energy storage module that is different than the first energy storage module. The first energy storage module may have a cell configuration, a cell chemistry, a cell number, a controller or another characteristic different than a like characteristic of the second energy storage module. |
| FILED | Monday, March 31, 2008 |
| APPL NO | 12/059385 |
| ART UNIT | 3618 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Motor vehicles 180/65.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382489 | Kacker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karan Kacker (Atlanta, Georgia); Suresh K. Sitaraman (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Karan Kacker (Atlanta, Georgia); Suresh K. Sitaraman (Atlanta, Georgia) |
| ABSTRACT | Disclosed are apparatus comprising single-path and multiple-path compliant interconnects that are coupled between electrical contacts and that allow for increased electrical performance without compromising mechanical reliability. Exemplary apparatus comprises a conductive vertical anchor coupled at a first end to an electrical contact; and one or more conductive arcuate beams coupled at a first end to a second end of the vertical anchor, and coupled at a second end to a second electrical contact. One electrical contact comprises a die contact pad and the other electrical contact comprises a substrate contact pad. Alternatively, one electrical contact comprises a substrate contact pad and the other electrical contact comprises a printed circuit board contact pad. Also, one electrical contact comprises a die contact pad and the other electrical contact comprises a printed circuit board contact pad. Methods of fabricating the apparatus are also disclosed. |
| FILED | Friday, March 30, 2012 |
| APPL NO | 13/435977 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/66 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08382858 | Santore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Maria M. Santore (Sunderland, Massachusetts); Jung Zhang (Neenah, Wisconsin); Vincent Rotello (Amherst, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Maria M. Santore (Sunderland, Massachusetts); Jung Zhang (Neenah, Wisconsin); Vincent Rotello (Amherst, Massachusetts) |
| ABSTRACT | Textured heterogeneous surfaces and related articles as can be used in conjunction with methods for selective sensing and/or separation. When used for selective particle separation such a system can comprise a heterogeneous surface comprising a surface member and a plurality of components extending therefrom, such components spaced about and having a surface density, with heterogeneity comprising different interactions of the surface member and of the extended components with a particle exposed thereto. Various surface heterogeneities and different interactions can be utilized. However, in certain embodiments, competing electrostatic interactions, or a combination of electrostatic and non-electrostatic interactions, with a particle can be utilized. Such a system can utilize a surface member having a charge difference with respect to the components extending therefrom. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/491851 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Chemistry: Physical processes 023/293.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383059 | Chang-Yen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David A. Chang-Yen (West Jordan, Utah); Sriram Natarajan (Salt Lake City, Utah); Josh Eckman (West Bountiful, Utah); Bruce K. Gale (Salt Lake City, Utah); David Myszka (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | David A. Chang-Yen (West Jordan, Utah); Sriram Natarajan (Salt Lake City, Utah); Josh Eckman (West Bountiful, Utah); Bruce K. Gale (Salt Lake City, Utah); David Myszka (Salt Lake City, Utah) |
| ABSTRACT | Disclosed is a spotter device and methods for the formation of microassays, biochips, biosensors, and cell cultures. The spotter may be used to deposit highly concentrated spots of protein or other materials on a microarray slide, wafer, or other surface. It may also be used to perform various chemistry steps on the same spots. The spotter increases the surface density of substances at each spot by directing a flow the desired substance (or a solution thereof) over the spot area until surface saturation is accomplished. The spotter may be loaded by well plate handling equipment. The spotter uses wells, microfluidic conduits, and orifices to deposit proteins, other biomolecules, or chemicals on a spot on a separate surface. Each orifice is connected to two wells via microconduits. When the spotter contacts a surface, a seal is formed between the orifices and the surface. The same or different substances may be flowed across each orifice. Any number of orifices may be incorporated into a spotter. The spotter is particularly useful for depositing proteins in high concentrations on a surface, since the spotter may be placed on a surface for an extended period of time. |
| FILED | Friday, September 30, 2005 |
| APPL NO | 11/241060 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/502 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383061 | Prakash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Manu Prakash (Cambridge, Massachusetts); Neil Gershenfeld (Somerville, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Manu Prakash (Cambridge, Massachusetts); Neil Gershenfeld (Somerville, Massachusetts) |
| ABSTRACT | Fluid-based no-moving part logic devices are constructed from complex sequences of micro- and nanofluidic channels, on-demand bubble/droplet modulators and generators for programming the devices, and micro- and nanofluidic droplet/bubble memory elements for storage and retrieval of biological or chemical elements. The input sequence of bubbles/droplets encodes information, with the output being another sequence of bubbles/droplets or on-chip chemical synthesis. For performing a set of reactions/tasks or process control, the modulators can be used to program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the micro- or nanofluidic channel sequence, utilizing the generated droplets/bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries. Various devices, including logic gates, non-volatile bistable memory, ring oscillators, bubble synchronizers, analysis chips, and printers have been designed. |
| FILED | Monday, April 04, 2011 |
| APPL NO | 13/079774 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/502 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383092 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce P. Lee (Madison, Wisconsin); Laura Vollenweider (Middleton, Wisconsin); John L. Murphy (Madison, Wisconsin); Fangmin Xu (Middleton, Wisconsin); Jeffrey L. Dalsin (Madison, Wisconsin); Jeanne Virosco (Madison, Wisconsin); William Lew (Mendota Heights, Minnesota); Jed White (Madison, Wisconsin) |
| ASSIGNEE(S) | KNC NER Acquisition Sub, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Bruce P. Lee (Madison, Wisconsin); Laura Vollenweider (Middleton, Wisconsin); John L. Murphy (Madison, Wisconsin); Fangmin Xu (Middleton, Wisconsin); Jeffrey L. Dalsin (Madison, Wisconsin); Jeanne Virosco (Madison, Wisconsin); William Lew (Mendota Heights, Minnesota); Jed White (Madison, Wisconsin) |
| ABSTRACT | The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons. |
| FILED | Monday, September 28, 2009 |
| APPL NO | 12/568527 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383113 | Acton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Acton (Quakertown, Pennsylvania); Zhiqiang An (Ambler, Pennsylvania); Andrew J. Bett (Lansdale, Pennsylvania); Robert Breese (Quakertown, Pennsylvania); Lei Chang (Westmont, Illinois); Elizabeth Chen Dodson (Souderton, Pennsylvania); Gene Kinney (Collegeville, Pennsylvania); William Klein (Winetka, Illinois); Mary P. Lambert (Glenview, Illinois); Xiaoping Liang (Collegeville, Pennsylvania); Paul Shughrue (West Chester, Pennsylvania); William R. Strohl (Bridgewater, New Jersey); Kristen Viola (Chicago, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Merck Sharp and Dohme Corp. (Rahway, New Jersey) |
| INVENTOR(S) | Paul Acton (Quakertown, Pennsylvania); Zhiqiang An (Ambler, Pennsylvania); Andrew J. Bett (Lansdale, Pennsylvania); Robert Breese (Quakertown, Pennsylvania); Lei Chang (Westmont, Illinois); Elizabeth Chen Dodson (Souderton, Pennsylvania); Gene Kinney (Collegeville, Pennsylvania); William Klein (Winetka, Illinois); Mary P. Lambert (Glenview, Illinois); Xiaoping Liang (Collegeville, Pennsylvania); Paul Shughrue (West Chester, Pennsylvania); William R. Strohl (Bridgewater, New Jersey); Kristen Viola (Chicago, Illinois) |
| ABSTRACT | The present invention relates to antibodies that differentially recognize multi-dimensional conformations of Aβ-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid β 1-42. |
| FILED | Wednesday, February 08, 2012 |
| APPL NO | 13/368742 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383412 | Zamborini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francis P. Zamborini (Louisville, Kentucky); Radhika Dasari (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Francis P. Zamborini (Louisville, Kentucky); Radhika Dasari (Louisville, Kentucky) |
| ABSTRACT | Sensors and switches for detecting hydrogen include an electrically-insulating support; a first and second electrode; and a palladium structure alone or in combination with an organic insulating film. The palladium structures of the sensors are deposited on and contact a first electrode and a portion of the palladium structure extends to and contacts the second electrode to create a conductive path. The palladium structures of the switches are deposited on and contact a first electrode and a portion of the palladium structures extend to and contact an organic insulating film deposited on the second electrode. Upon exposure of the switch to hydrogen, portions of the palladium structure extend through the film and contact the second electrode to create a conductive path. Methods of detecting hydrogen and methods of fabricating a sensor for detecting an analyte of interest are also provided. |
| FILED | Friday, October 30, 2009 |
| APPL NO | 12/609669 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/144 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383425 | Hsieh-Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Linda Hsieh-Wilson (San Marino, California); Nelly Khidekel (Pasadena, California); Hwan-Ching Tai (Pasadena, California); Sabine Arndt (Dortmund, Germany) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Linda Hsieh-Wilson (San Marino, California); Nelly Khidekel (Pasadena, California); Hwan-Ching Tai (Pasadena, California); Sabine Arndt (Dortmund, Germany) |
| ABSTRACT | The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with post-translational glycosylations. The methods can be used to detect O-GlcNAc posttranslational modifications on proteins on which such modifications were undetectable using other techniques. In one embodiment, the method exploits the ability of an engineered mutant of β-1,4-galactosyltransferase to selectively transfer an unnatural ketone functionality onto O-GlcNAc glycosylated proteins. Once transferred, the ketone moiety serves as a versatile handle for the attachment of biotin, thereby enabling detection of the modified protein. The approach permits the rapid visualization of proteins that are at the limits of detection using traditional methods. Further, the preferred embodiments can be used for detection of certain disease states, such as cancer, Alzheimer's disease, neurodegeneration, cardiovascular disease, and diabetes. |
| FILED | Thursday, October 21, 2010 |
| APPL NO | 12/909402 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/544 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383553 | Minns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard A. Minns (Arlington, Massachusetts); David Waller (Lexington, Massachusetts) |
| ASSIGNEE(S) | Merck Patent GmbH (Darmstadt, Germany) |
| INVENTOR(S) | Richard A. Minns (Arlington, Massachusetts); David Waller (Lexington, Massachusetts) |
| ABSTRACT | Novel dyes, as well as related photovoltaic cells, components, systems, and methods, are disclosed. |
| FILED | Tuesday, September 23, 2008 |
| APPL NO | 12/236150 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383561 | Sawyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | W. Gregory Sawyer (Gainesville, Florida); David L. Burris (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, inc. (Gainesville, Florida) |
| INVENTOR(S) | W. Gregory Sawyer (Gainesville, Florida); David L. Burris (Gainesville, Florida) |
| ABSTRACT | A PTFE-based composite material includes a PTFE major phase filled with a metal oxide minor phase. The major phase is intermixed with the metal oxide minor phase, wherein the minor phase includes a plurality of irregularly shaped metal oxide nanoparticles. The irregularly shaped nanoparticles provide substantial reductions in steady state wear rate over otherwise similar nanocomposites. The metal oxide can comprise aluminum oxide. |
| FILED | Tuesday, August 24, 2010 |
| APPL NO | 12/861985 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Solid anti-friction devices, materials therefor, lubricant or separant compositions for moving solid surfaces, and miscellaneous mineral oil compositions 58/106 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383697 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gerald O. Wilson (Champaign, Illinois); Mary M. Caruso (Urbana, Illinois); Benjamin J. Blaiszik (Urbana, Illinois); James W. Henderson (Winnetka, Illinois); Christopher Britt (St. Louis, Missouri); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois); Nancy R. Sottos (Champaign, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Gerald O. Wilson (Champaign, Illinois); Mary M. Caruso (Urbana, Illinois); Benjamin J. Blaiszik (Urbana, Illinois); James W. Henderson (Winnetka, Illinois); Christopher Britt (St. Louis, Missouri); Jeffrey S. Moore (Savoy, Illinois); Scott R. White (Champaign, Illinois); Nancy R. Sottos (Champaign, Illinois) |
| ABSTRACT | A composite material precursor composition includes a matrix precursor, a first plurality of capsules including a liquid polymerizer, an activator, and an accelerant. The liquid polymerizer polymerizes when in contact with the activator, and the accelerant is an accelerant for the polymerization of the liquid polymerizer. The composite material precursor may be used to form a composite material that includes a solid polymer matrix, the first plurality of capsules in the solid polymer matrix, the activator in the solid polymer matrix, and the accelerant in the solid polymer matrix. |
| FILED | Thursday, April 29, 2010 |
| APPL NO | 12/769904 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 523/120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08383725 — Polyester based degradable materials and implantable biomedical articles formed therefrom
| US 08383725 | Ashby et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Valerie Ashby (Durham, North Carolina); David Olson (Minneapolis, Minnesota) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Valerie Ashby (Durham, North Carolina); David Olson (Minneapolis, Minnesota) |
| ABSTRACT | A method of making an aliphatic polyester prepolymer, comprising: reacting, alone or in combination with other reactants, a diol with at least a first diacid (or a diester of said first diacid) to produce an aliphatic polyester prepolymer. The first diacid is preferably a trans-beta-hydromuconic acid (HMA). In some embodiments, the diol contains at least one ether linkage. In some embodiments the diol is further reacted with at a second diacid, or a diester of said second diacid, wherein said second diacid is different from said first diacid. Prepolymers produced from such processes and articles formed therefrom are also described. |
| FILED | Monday, August 08, 2011 |
| APPL NO | 13/204774 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 525/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383763 | McGrath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James E. McGrath (Blacksburg, Virginia); Michael Hickner (Blacksburg, Virginia); Feng Wang (Blacksburg, Virginia); Yu-Seung Kim (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | James E. McGrath (Blacksburg, Virginia); Michael Hickner (Blacksburg, Virginia); Feng Wang (Blacksburg, Virginia); Yu-Seung Kim (Blacksburg, Virginia) |
| ABSTRACT | Sulfonated polymers are made by the direct polymerization of a sulfonated monomer to form the sulfonated polymers. The types of sulfonated polymers may include polysulfones or polyimides. The sulfonated polymers can be formed into membranes that may be used in proton exchange membrane fuel cells or as ion exchange membranes. The membranes formed from the sulfonated polymers exhibit improved properties over that of Nafion®. A heteropoly acid may be added to the sulfonated polymer to form a nanocomposite membrane in which the heteropoly acid is highly dispersed. The addition of a heteropoly acid to the sulfonated polymer increases the thermal stability of the membrane, enhances the conductivity above 100° C., and reduces the water uptake of the membrane. |
| FILED | Thursday, July 29, 2010 |
| APPL NO | 12/845874 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/391 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384372 | Behlow, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Herbert W. Behlow, Jr. (Greenville, South Carolina); Bevan C. Elliott (Greenville, South Carolina); Gayatri D. Keskar (Stamford, Connecticut); Doyl E. Dickel (Central, South Carolina); Malcolm J. Skove (Clemson, South Carolina); Apparao M. Rao (Anderson, South Carolina) |
| ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
| INVENTOR(S) | Herbert W. Behlow, Jr. (Greenville, South Carolina); Bevan C. Elliott (Greenville, South Carolina); Gayatri D. Keskar (Stamford, Connecticut); Doyl E. Dickel (Central, South Carolina); Malcolm J. Skove (Clemson, South Carolina); Apparao M. Rao (Anderson, South Carolina) |
| ABSTRACT | A method and system is disclosed to detect and analyze an electric signal based on movement between an element and a counter electrode influenced by a nonlinear electric field produced by an electrical signal impressed between the element and counter electrode. Through detection of changes in the distance between the element and the counter electrode characteristics of the element and/or the environment of the element may be ascertained. Changes in the distance between the element and the counter electrode may be monitored based on changes in the value of capacitance between the element and counter electrode. The disclosed devices and methods may be employed to detect, for instance, presence of chemical/biological species in a sample or measure physical parameters of a sample such as pressure/acceleration, density, viscosity, magnetic force, temperature, and/or extremely small masses. |
| FILED | Monday, October 05, 2009 |
| APPL NO | 12/573433 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/76.420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384409 | Kummel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew C. Kummel (San Diego, California); Dengliang Yang (Union City, California); William C. Trogler (Del Mar, California); Thomas Gredig (Huntington Beach, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andrew C. Kummel (San Diego, California); Dengliang Yang (Union City, California); William C. Trogler (Del Mar, California); Thomas Gredig (Huntington Beach, California) |
| ABSTRACT | An embodiment of the invention is an organic thin film transistor chemical sensor. The sensor includes a substrate. A gate electrode is isolated from drain and source electrodes by gate dielectric. An organic ultra-thin semiconductor thin film is arranged with respect to the gate, source and drain electrodes to act as a conduction channel in response to appropriate gate, source and drain potentials. The organic ultra-thin film is permeable to a chemical analyte of interest and consists of one or a few atomic or molecular monolayers of material. An example sensor array system includes a plurality of sensors of the invention. In a preferred embodiment, a sensor chip having a plurality of sensors is mounted in a socket, for example by wire bonding. The socket provides thermal and electrical interference isolation for the sensor chip from associated sensing circuitry that is mounted on a common substrate, such as a PCB (printed circuit board). A method of operating an organic thin film transistor chemical sensor exposes the sensor to a suspected analyte. A low duty cycle voltage pulse train is applied to the gate electrode to reduce baseline drift while sensing for a conduction channel change. |
| FILED | Monday, May 05, 2008 |
| APPL NO | 12/597976 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/762.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384894 | Fink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Manfred Fink (Austin, Texas); Philip Varghese (Austin, Texas); Jacek Borysow (Atlantic Mine, Michigan) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas); Michigan Technological University (Houghton, Michigan) |
| INVENTOR(S) | Manfred Fink (Austin, Texas); Philip Varghese (Austin, Texas); Jacek Borysow (Atlantic Mine, Michigan) |
| ABSTRACT | A Raman analyzer for analyzing light emitted from a Raman cell is provided that has a beam splitter configured to split the light emitted from the Raman cell into a first beam and a second beam. An atomic vapor filter can be used to filter a Raman scattered line from the first beam and a chopper system can periodically interrupt the first and second beams that are directed towards a photo detector, which can convert light from the first and second beams into an electrical signal. The signal output from the photo detector can optionally be amplified, digitized, Fourier filtered, and/or subjected to Fourier analysis. |
| FILED | Friday, January 28, 2011 |
| APPL NO | 13/015878 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384991 | Kieu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Khanh Kieu (Ithaca, New York); Frank W. Wise (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Khanh Kieu (Ithaca, New York); Frank W. Wise (Ithaca, New York) |
| ABSTRACT | A saturable absorber (SA) is constructed using a fiber taper embedded in a carbon nanotube/polymer composite. A fiber taper is made by heating and pulling a small part of standard optical fiber. At the taper's waist light is guided by the glass-air interface, with an evanescent field protruding out of the taper. Carbon nanotubes mixed with an appropriate polymer host material are then wrapped around the fiber taper to interact with the evanescent field. Saturable absorption is possible due to the unique optical properties of the carbon nanotubes. The device can be used in mode-locked lasers where it initiates and stabilizes the pulses circulating around the laser cavity. The SA can be used in various laser cavities, and can enable different pulse evolutions such as solitons, self-similar pulses and dissipative solitons. Other applications include but are not limited to optical switching, pulse cleanup and pulse compression. |
| FILED | Thursday, December 23, 2010 |
| APPL NO | 12/977657 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/337 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385047 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Huikai Xie (Gainsville, Florida); Khai D. T. Ngo (Blacksburg, Virginia) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Huikai Xie (Gainsville, Florida); Khai D. T. Ngo (Blacksburg, Virginia) |
| ABSTRACT | A multi-layer film-stack and method for forming the multilayer film-stack is given where a series of alternating layers of conducting and dielectric materials are deposited such that the conducting layers can be selectively addressed. The use of the method to form integratable high capacitance density capacitors and complete the formation of an integrated power system-on-a-chip device including transistors, conductors, inductors, and capacitors is also given. |
| FILED | Monday, April 02, 2007 |
| APPL NO | 12/295347 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/306.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385693 | Schmidt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Holger Schmidt (Capitola, California); Aaron Roe Hawkins (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Holger Schmidt (Capitola, California); Aaron Roe Hawkins (Provo, Utah) |
| ABSTRACT | An optical waveguide is provided comprising a non-solid core layer surrounded by a solid-state material, wherein light can be transmitted with low loss through the non-solid core layer. A vapor reservoir is in communication with the optical waveguide. One implementation of the invention employs a monolithically integrated vapor cell, e.g., an alkali vapor cell, using anti-resonant reflecting optical waveguides, or ARROW waveguides, on a substrate. |
| FILED | Thursday, June 16, 2011 |
| APPL NO | 13/161748 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386190 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ker-Chau Li (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ker-Chau Li (Los Angeles, California) |
| ABSTRACT | A system and method for identifying high order associations between variables in complex systems that is particularly useful where there is no correlation or weak correlation between variables due to the influence of a third variable, a ternary relationship. The ternary relationship describes how the variation in the pattern of association between a pair of variables, including its sign and strength, is mediated by a third variable. In one embodiment applied to gene expression data, the activity of pairs of correlated genes due to the activity of one or more third genes is shown. |
| FILED | Monday, October 24, 2011 |
| APPL NO | 13/280167 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386892 | Jamieson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kyle Jamieson (Cambridge, Massachusetts); Hari Balakrishnan (Belmont, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kyle Jamieson (Cambridge, Massachusetts); Hari Balakrishnan (Belmont, Massachusetts) |
| ABSTRACT | A method, apparatus and computer program product for providing partial packet recovery (PPR) for wireless networks is presented. PPR incorporates an expanded physical layer (PHY) interface that provides PHY-independent hints to higher layers about the PHY's confidence in each bit it decodes, and a technique to recover data even when a packet preamble is corrupted and not decodable at the receiver. Also described is an asynchronous link-layer automatic repeat request (ARQ) protocol built on PPR that allows a receiver to compactly encode a request for retransmission of only those bits in a packet that are likely in error. |
| FILED | Monday, November 05, 2007 |
| APPL NO | 11/934991 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/780 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08381631 | Chu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Henry S. Chu (Idaho Falls, Idaho); Thomas M. Lillo (Idaho Falls, Idaho); Thomas M. Zagula (Rigby, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Henry S. Chu (Idaho Falls, Idaho); Thomas M. Lillo (Idaho Falls, Idaho); Thomas M. Zagula (Rigby, Idaho) |
| ABSTRACT | Laminate armor and methods of manufacturing laminate armor. Specifically, laminate armor plates comprising a commercially pure titanium layer and a titanium alloy layer bonded to the commercially pure titanium outer layer are disclosed, wherein an average thickness of the titanium alloy inner layer is about four times an average thickness of the commercially pure titanium outer layer. In use, the titanium alloy layer is positioned facing an area to be protected. Additionally, roll-bonding methods for manufacturing laminate armor plates are disclosed. |
| FILED | Monday, December 01, 2008 |
| APPL NO | 12/325510 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/36.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381632 | Chu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Henry S. Chu (Idaho Falls, Idaho); Benjamin R. Langhorst (Idaho Falls, Idaho); Michael P. Bakas (Ammon, Idaho); Gary L. Thinnes (Idaho Falls, Idaho) |
| ASSIGNEE(S) | The United States of America as represented by the Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Henry S. Chu (Idaho Falls, Idaho); Benjamin R. Langhorst (Idaho Falls, Idaho); Michael P. Bakas (Ammon, Idaho); Gary L. Thinnes (Idaho Falls, Idaho) |
| ABSTRACT | The disclosure provides a shock absorbing layer comprised of one or more shock absorbing cells, where a shock absorbing cell is comprised of a cell interior volume containing a plurality of hydrogel particles and a free volume, and where the cell interior volume is surrounded by a containing layer. The containing layer has a permeability such that the hydrogel particles when swollen remain at least partially within the cell interior volume when subjected to a design shock pressure wave, allowing for force relaxation through hydrogel compression response. Additionally, the permeability allows for the flow of exuded free water, further dissipating wave energy. In an embodiment, a plurality of shock absorbing cells is combined with a penetration resistant material to mitigate the transmitted shock wave generated by an elastic precursor wave in the penetration resistant material. |
| FILED | Monday, February 07, 2011 |
| APPL NO | 13/022065 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/36.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381806 | Menotti |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Louis Menotti (Dickinson, Texas) |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | James Louis Menotti (Dickinson, Texas) |
| ABSTRACT | Systems for coupling ends of elongated heaters and methods of using such systems to treat a subsurface formation are described herein. A system may include two elongated heaters with an end portion of one heater abutted or near to an end portion of the other heater and a core coupling material. The core coupling material may extend between the two elongated heaters. The elongated heaters may include cores and at least one conductor substantially concentrically surrounds the cores. The cores may have a lower melting point than the conductors. At least one end portion of the conductor may have a beveled edge. The gap formed by the beveled edge may be filled with a coupling material for coupling the one or more conductors. One end portion of at least one core may have a recessed opening and the core coupling material may be partially inside the recessed opening. |
| FILED | Friday, April 20, 2007 |
| APPL NO | 11/788869 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Wells 166/60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08381815 | Karanikas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Michael Karanikas (Houston, Texas); Harold J. Vinegar (Bellaire, Texas) |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | John Michael Karanikas (Houston, Texas); Harold J. Vinegar (Bellaire, Texas) |
| ABSTRACT | A method for treating a tar sands formation includes providing heat to at least part of a hydrocarbon layer in the formation from a plurality of heaters located in the formation. The heat is allowed to transfer from the heaters to at least a portion of the formation. Fluids are produced from the formation through at least one production well that is located in at least two zones in the formation. The first zone has an initial permeability of at least 1 darcy. The second zone has an initial of at most 0.1 darcy. The two zones are separated by a substantially impermeable barrier. |
| FILED | Friday, April 18, 2008 |
| APPL NO | 12/106008 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Wells 166/302 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383021 | Krumhansl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James L. Krumhansl (Albuquerque, New Mexico); Tina M. Nenoff (Sandia Park, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | James L. Krumhansl (Albuquerque, New Mexico); Tina M. Nenoff (Sandia Park, New Mexico) |
| ABSTRACT | Materials and methods of synthesizing mixed-layered bismuth oxy-iodine materials, which can be synthesized in the presence of aqueous radioactive iodine species found in caustic solutions (e.g. NaOH or KOH). This technology provides a one-step process for both iodine sequestration and storage from nuclear fuel cycles. It results in materials that will be durable for repository conditions much like those found in Waste Isolation Pilot Plant (WIPP) and estimated for Yucca Mountain (YMP). By controlled reactant concentrations, optimized compositions of these mixed-layered bismuth oxy-iodine inorganic materials are produced that have both a high iodine weight percentage and a low solubility in groundwater environments. |
| FILED | Thursday, November 12, 2009 |
| APPL NO | 12/617051 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/625 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383026 | Luebke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David R. Luebke (Bethel Park, Pennsylvania); Shan Wickramanayake (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | U.S Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | David R. Luebke (Bethel Park, Pennsylvania); Shan Wickramanayake (Pittsburgh, Pennsylvania) |
| ABSTRACT | One or more embodiments relates to the production of a fabricated fiber having an asymmetric polymer network and having an immobilized liquid such as an ionic liquid within the pores of the polymer network. The process produces the fabricated fiber in a dry-wet spinning process using a homogenous dope solution, providing significant advantage over current fabrication methods for liquid-supporting polymers. The fabricated fibers may be effectively utilized for the separation of a chemical species from a mixture based on the selection of the polymer, the liquid, and the solvent utilized in the dope. |
| FILED | Thursday, October 21, 2010 |
| APPL NO | 12/909180 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/178.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383036 | Sloan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark A. Sloan (Spring Branch, Texas); Jeevalatha Vivekananda (San Antonio, Texas); Eric A. Holwitt (San Antonio, Texas); Johnathan L. Kiel (Universal City, Texas) |
| ASSIGNEE(S) | Conceptual Mindworks, Inc. (San Antonio, Texas) |
| INVENTOR(S) | Mark A. Sloan (Spring Branch, Texas); Jeevalatha Vivekananda (San Antonio, Texas); Eric A. Holwitt (San Antonio, Texas); Johnathan L. Kiel (Universal City, Texas) |
| ABSTRACT | The present invention concerns methods, compositions and apparatus for neutralizing bioagents, wherein bioagents comprise biowarfare agents, biohazardous agents, biological agents and/or infectious agents. The methods comprise exposing the bioagent to an organic semiconductor and exposing the bioagent and organic semiconductor to a source of energy. Although any source of energy is contemplated, in some embodiments the energy comprises visible light, ultraviolet, infrared, radiofrequency, microwave, laser radiation, pulsed corona discharge or electron beam radiation. Exemplary organic semiconductors include DAT and DALM. In certain embodiments, the organic semiconductor may be attached to one or more binding moieties, such as an antibody, antibody fragment, or nucleic acid ligand. Preferably, the binding moiety has a binding affinity for one or more bioagents to be neutralized. Other embodiments concern an apparatus comprising an organic semiconductor and an energy source. In preferred embodiments, the methods, compositions and apparatus are used for neutralizing anthrax spores. |
| FILED | Monday, December 20, 2010 |
| APPL NO | 12/973681 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383077 | Thackeray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael M. Thackeray (Naperville, Illinois); Sun-Ho Kang (Naperville, Illinois); Christopher S. Johnson (Naperville, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Michael M. Thackeray (Naperville, Illinois); Sun-Ho Kang (Naperville, Illinois); Christopher S. Johnson (Naperville, Illinois) |
| ABSTRACT | A method of stabilizing a metal oxide or lithium-metal-oxide electrode comprises contacting a surface of the electrode, prior to cell assembly, with an aqueous or a non-aqueous acid solution having a pH greater than 4 but less than 7 and containing a stabilizing salt, for a time and at a temperature sufficient to etch the surface of the electrode and introduce stabilizing anions and cations from the salt into said surface. The structure of the bulk of the electrode remains unchanged during the acid treatment. The stabilizing salt comprises fluoride and at least one cationic material selected from the group consisting of ammonium, phosphorus, titanium, silicon, zirconium, aluminum, and boron. |
| FILED | Tuesday, February 14, 2012 |
| APPL NO | 13/396338 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry of inorganic compounds 423/594.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383237 | Culver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James N. Culver (Potomac, Maryland); Elizabeth Royston (Walkersville, Maryland); Adam Brown (Berwyn Heights, Maryland); Michael Harris (Lafeyette, Indiana) |
| ASSIGNEE(S) | University of Maryland, College Park (Baltimore, Maryland); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | James N. Culver (Potomac, Maryland); Elizabeth Royston (Walkersville, Maryland); Adam Brown (Berwyn Heights, Maryland); Michael Harris (Lafeyette, Indiana) |
| ABSTRACT | The present invention relates to a system and method providing for increased silica growth on a bio-template, wherein the bio-template is pretreated with aniline to produce a uniform silica attractive surface and yielding a significant silica layers of at least 10 nm, and more preferably at least 20 nm in thickness, thereby providing for a high degree of stability to the bio-template. |
| FILED | Monday, May 31, 2010 |
| APPL NO | 12/790926 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Stock material or miscellaneous articles 428/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383385 | Teter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sarah Teter (Mountain View, California); Connie Ward (Hamilton, Missouri); Joel Cherry (Winters, California); Aubrey Jones (Davis, California); Paul Harris (Carnation, Washington); Jung Yi (Sacramento, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Sarah Teter (Mountain View, California); Connie Ward (Hamilton, Missouri); Joel Cherry (Winters, California); Aubrey Jones (Davis, California); Paul Harris (Carnation, Washington); Jung Yi (Sacramento, California) |
| ABSTRACT | The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences. |
| FILED | Wednesday, January 19, 2011 |
| APPL NO | 13/009524 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384004 | Rowland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark S. Rowland (Alamo, California); Raymond A. Alvarez (Berkeley, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security (Livermore, California) |
| INVENTOR(S) | Mark S. Rowland (Alamo, California); Raymond A. Alvarez (Berkeley, California) |
| ABSTRACT | Embodiments are directed to a digital data acquisition method that collects data regarding nuclear fission at high rates and performs real-time preprocessing of large volumes of data into directly useable forms for use in a system that performs non-destructive assaying of nuclear material and assemblies for mass and multiplication of special nuclear material (SNM). Pulses from a multi-detector array are fed in parallel to individual inputs that are tied to individual bits in a digital word. Data is collected by loading a word at the individual bit level in parallel, to reduce the latency associated with current shift-register systems. The word is read at regular intervals, all bits simultaneously, with no manipulation. The word is passed to a number of storage locations for subsequent processing, thereby removing the front-end problem of pulse pileup. The word is used simultaneously in several internal processing schemes that assemble the data in a number of more directly useable forms. The detector includes a multi-mode counter that executes a number of different count algorithms in parallel to determine different attributes of the count data. |
| FILED | Friday, January 22, 2010 |
| APPL NO | 12/692323 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384020 | Jesse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen Jesse (Knoxville, Tennessee); Gary J. Van Berkel (Clinton, Tennessee); Olga S. Ovchinnikova (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Stephen Jesse (Knoxville, Tennessee); Gary J. Van Berkel (Clinton, Tennessee); Olga S. Ovchinnikova (Knoxville, Tennessee) |
| ABSTRACT | A system and method for sub-micron analysis of a chemical composition of a specimen are described. The method includes providing a specimen for evaluation and a thermal desorption probe, thermally desorbing an analyte from a target site of said specimen using the thermally active tip to form a gaseous analyte, ionizing the gaseous analyte to form an ionized analyte, and analyzing a chemical composition of the ionized analyte. The thermally desorbing step can include heating said thermally active tip to above 200° C., and positioning the target site and the thermally active tip such that the heating step forms the gaseous analyte. The thermal desorption probe can include a thermally active tip extending from a cantilever body and an apex of the thermally active tip can have a radius of 250 nm or less. |
| FILED | Friday, September 24, 2010 |
| APPL NO | 12/890225 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384035 | Borade et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ramesh B. Borade (Livermore, California); Edith Bourret-Courchesne (Berkeley, California); Stephen E. Derenzo (Pinole, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ramesh B. Borade (Livermore, California); Edith Bourret-Courchesne (Berkeley, California); Stephen E. Derenzo (Pinole, California) |
| ABSTRACT | The present invention provides for a composition comprising an inorganic scintillator comprising a lanthanide-doped barium phosphorous oxide useful for detecting nuclear material. |
| FILED | Monday, October 25, 2010 |
| APPL NO | 12/911583 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/361.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384239 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeremy B. Campbell (Torrance, California); Steve Newson (Redondo Beach, California) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Jeremy B. Campbell (Torrance, California); Steve Newson (Redondo Beach, California) |
| ABSTRACT | Embodiments of DC source assemblies of power inverter systems of the type suitable for deployment in a vehicle having an electrically grounded chassis are provided. An embodiment of a DC source assembly comprises a housing, a DC source disposed within the housing, a first terminal, and a second terminal. The DC source also comprises a first capacitor having a first electrode electrically coupled to the housing, and a second electrode electrically coupled to the first terminal. The DC source assembly further comprises a second capacitor having a first electrode electrically coupled to the housing, and a second electrode electrically coupled to the second terminal. |
| FILED | Thursday, July 16, 2009 |
| APPL NO | 12/503946 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical transmission or interconnection systems 37/10.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384338 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bin Lu (Kenosha, Wisconsin); Thomas G. Habetler (Snellville, Georgia); Pinjia Zhang (Atlanta, Georgia) |
| ASSIGNEE(S) | Eaton Corporation (Cleveland, Ohio) |
| INVENTOR(S) | Bin Lu (Kenosha, Wisconsin); Thomas G. Habetler (Snellville, Georgia); Pinjia Zhang (Atlanta, Georgia) |
| ABSTRACT | A system and method for determining the stator winding resistance of AC motors is provided. The system includes an AC motor drive having an input connectable to an AC source and an output connectable to an input terminal of an AC motor, a pulse width modulation (PWM) converter having switches therein to control current flow and terminal voltages in the AC motor, and a control system connected to the PWM converter. The control system generates a command signal to cause the PWM converter to control an output of the AC motor drive corresponding to an input to the AC motor, selectively generates a modified command signal to cause the PWM converter to inject a DC signal into the output of the AC motor drive, and determines a stator winding resistance of the AC motor based on the DC signal of at least one of the voltage and current. |
| FILED | Friday, January 30, 2009 |
| APPL NO | 12/363413 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Motive power systems 318/811 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384381 | Sillerud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Laurel Sillerud (Albuquerque, New Mexico); Todd M. Alam (Cedar Crest, New Mexico); Andrew F. McDowell (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC . UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Laurel Sillerud (Albuquerque, New Mexico); Todd M. Alam (Cedar Crest, New Mexico); Andrew F. McDowell (Albuquerque, New Mexico) |
| ABSTRACT | A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid. |
| FILED | Tuesday, March 09, 2010 |
| APPL NO | 12/720499 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384487 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen Fulton Smith (Loudon, Tennessee); James Anthony Moore (Powell, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Stephen Fulton Smith (Loudon, Tennessee); James Anthony Moore (Powell, Tennessee) |
| ABSTRACT | An orthogonally referenced integrated ensemble for navigation and timing includes a dual-polyhedral oscillator array, including an outer sensing array of oscillators and an inner clock array of oscillators situated inside the outer sensing array. The outer sensing array includes a first pair of sensing oscillators situated along a first axis of the outer sensing array, a second pair of sensing oscillators situated along a second axis of the outer sensing array, and a third pair of sensing oscillators situated along a third axis of the outer sensing array. The inner clock array of oscillators includes a first pair of clock oscillators situated along a first axis of the inner clock array, a second pair of clock oscillators situated along a second axis of the inner clock array, and a third pair of clock oscillators situated along a third axis of the inner clock array. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/083366 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Oscillators 331/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384711 | Wald et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ingo Wald (Salt Lake City, Utah); Santiago Ize (Salt Lake City, Utah); Steven G. Parker (Salt Lake City, Utah); Aaron Knoll (Sandy, Utah) |
| ASSIGNEE(S) | The University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Ingo Wald (Salt Lake City, Utah); Santiago Ize (Salt Lake City, Utah); Steven G. Parker (Salt Lake City, Utah); Aaron Knoll (Sandy, Utah) |
| ABSTRACT | Ray tracing a three-dimensional scene using a grid. One example embodiment is a method for ray tracing a three-dimensional scene using a grid. In this example method, the three-dimensional scene is made up of objects that are spatially partitioned into a plurality of cells that make up the grid. The method includes a first act of computing a bounding frustum of a packet of rays, and a second act of traversing the grid slice by slice along a major traversal axis. Each slice traversal includes a first act of determining one or more cells in the slice that are overlapped by the frustum and a second act of testing the rays in the packet for intersection with any objects at least partially bounded by the one or more cells overlapped by the frustum. |
| FILED | Thursday, November 29, 2007 |
| APPL NO | 12/515812 |
| ART UNIT | 2677 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE44031 | Apel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho) |
| ABSTRACT | A method for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method comprises attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to the antigens in the array to form immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, to form an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity. |
| FILED | Wednesday, April 04, 2012 |
| APPL NO | 13/439400 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08383102 | Donovan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Donovan (Baltimore, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | David Donovan (Baltimore, Maryland) |
| ABSTRACT | Lysostaphin is a bacteriocin secreted by S. simulans to kill S. aureus, and has been shown to also be a potent antimicrobial for many antibiotic-resistant strains of S. aureus. By adding a ˜13 amino acid protein transduction domain (PTD) from the HIV-TAT protein to lysostaphin to form lysostaphin-PTD, both extracellular and intracellular forms of S. aureus and MRSA are killed in all (multiple) cell types examined. |
| FILED | Friday, May 21, 2010 |
| APPL NO | 12/784675 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383374 | Causey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas B. Causey (Gloucester, Massachusetts); Lonnie O'Neal Ingram (Gainesville, Florida); Keelnatham Shanmugam (Gainesville, Florida); Shengde Zhou (Dekalb, Illinois) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Thomas B. Causey (Gloucester, Massachusetts); Lonnie O'Neal Ingram (Gainesville, Florida); Keelnatham Shanmugam (Gainesville, Florida); Shengde Zhou (Dekalb, Illinois) |
| ABSTRACT | The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of the subject invention can be used to obtain products from native pathways as well as from recombinant pathways. In preferred embodiments, the subject invention provides new materials and methods for the efficient production of acetate and pyruvic acid. |
| FILED | Tuesday, June 07, 2011 |
| APPL NO | 13/154765 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/132 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383890 | Pan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhiqiang Pan (Oxford, Mississippi); Agnes M. Rimando (Oxford, Mississippi); Scott R. Baerson (Oxford, Mississippi) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Zhiqiang Pan (Oxford, Mississippi); Agnes M. Rimando (Oxford, Mississippi); Scott R. Baerson (Oxford, Mississippi) |
| ABSTRACT | This invention relates to the fatty acid desaturase genes, designated SbDES2 and SbDES3, cloned from an expressed sequence tag (EST) database prepared from isolated root hairs from sorghum. Heterologous expression of the cDNAs in S. cerevisiae revealed that recombinant SbDES2 converted palmitoleic acid (16:1Δ9) to hexadecadienoic acid (16:2Δ9, 12), and that recombinant SbDES3 was capable of converting hexadecadienoic acid into hexadecatrienoic acid (16:3Δ9, 12, 15). Desaturase enzymes capable of performing desaturation reactions producing a terminal double bond have not previously been characterized in a plant system. |
| FILED | Friday, December 15, 2006 |
| APPL NO | 11/639709 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/298 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384047 | Shur et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Shur (Latham, New York); Steven J. Britz (Laurel, Maryland) |
| ASSIGNEE(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Michael Shur (Latham, New York); Steven J. Britz (Laurel, Maryland) |
| ABSTRACT | A solution for managing illumination of an organism with ultraviolet light is provided. A set of ultraviolet fluorescence characteristics of the organism can be determined using fluorescence data for the organism. The set of ultraviolet fluorescence characteristics can be used to determine a set of target properties of the ultraviolet light. The set of target properties can be used to illuminate the organism with ultraviolet light. The illumination can be managed during growth of the organism, breeding of the organism, and/or maintenance of the organism after harvest. |
| FILED | Tuesday, December 21, 2010 |
| APPL NO | 12/973988 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/461.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP23422 | Ramming et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Ramming (Fresno, California); Ronald E. Tarailo (Fresno, California) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | David Ramming (Fresno, California); Ronald E. Tarailo (Fresno, California) |
| ABSTRACT | A new and distinct variety of grapevine denominated ‘Valley Pearl’ which is characterized by its early to mid-season ripening seedless fruit, attractive green coloration, its round fruit shape, its firm fruit texture with neutral sweet flavor, and its high production when spur pruned. |
| FILED | Thursday, August 25, 2011 |
| APPL NO | 13/199300 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08384115 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ting Li (Ventura, California) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Ting Li (Ventura, California) |
| ABSTRACT | An improved bond pad design for increased light extraction efficiency for use in light emitting diodes (LEDs) and LED packages. Embodiments of the present invention incorporate a structure that physically isolates the bond pads from the primary emission surface, forcing the current to flow away from the bond pads first before traveling down into the semiconductor material toward the active region. This structure reduces the amount of light that is generated in the area near the bond pads, so that less of the generated light is trapped underneath the bond pads and absorbed. |
| FILED | Friday, August 01, 2008 |
| APPL NO | 12/185031 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384887 | Lange et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steve R. Lange (Alamo, California); Paul Frank Marella (San Jose, California); Nat Ceglio (Pleasanton, California); Shiow-Hwei Hwang (Livermore, California); Tao-Yi Fu (Fremont, California) |
| ASSIGNEE(S) | KLA-Tencor Technologies Corp. (Milpitas, California) |
| INVENTOR(S) | Steve R. Lange (Alamo, California); Paul Frank Marella (San Jose, California); Nat Ceglio (Pleasanton, California); Shiow-Hwei Hwang (Livermore, California); Tao-Yi Fu (Fremont, California) |
| ABSTRACT | Methods and systems for inspection of a specimen using different parameters are provided. One computer-implemented method includes determining optimal parameters for inspection based on selected defects. This method also includes setting parameters of an inspection system at the optimal parameters prior to inspection. Another method for inspecting a specimen includes illuminating the specimen with light having a wavelength below about 350 nm and with light having a wavelength above about 350 nm. The method also includes processing signals representative of light collected from the specimen to detect defects or process variations on the specimen. One system configured to inspect a specimen includes a first optical subsystem coupled to a broadband light source and a second optical subsystem coupled to a laser. The system also includes a third optical subsystem configured to couple light from the first and second optical subsystems to an objective, which focuses the light onto the specimen. |
| FILED | Tuesday, June 08, 2010 |
| APPL NO | 12/796047 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/237.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385106 | Ong |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adrian E. Ong (Pleasanton, California) |
| ASSIGNEE(S) | Grandis, Inc. (San Jose, California) |
| INVENTOR(S) | Adrian E. Ong (Pleasanton, California) |
| ABSTRACT | A method and system for providing a magnetic memory are described. The method and system include providing memory array tiles (MATs), intermediate circuitry, global bit lines, global word lines, and global circuitry. Each MAT includes magnetic storage cells, bit lines, and word lines. Each of the magnetic storage cells includes at least one magnetic element and at least one selection device. The magnetic element(s) are programmable using write current(s) driven through the magnetic element(s). The bit lines and the word lines correspond to the magnetic storage cells. The intermediate circuitry controls read and write operations within the MATs. Each global bit line corresponds to a first portion of the plurality of MATs. Each global word line corresponds to a second portion of the MATs. The global circuitry selects and drives part of the global bit lines and part of the global word lines for the read and write operations. |
| FILED | Wednesday, September 23, 2009 |
| APPL NO | 12/565273 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08387158 | Perkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas T Perkins (Boulder, Colorado); Gavin M King (Columbia, Missouri); Ashley R Carter (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia) |
| INVENTOR(S) | Thomas T Perkins (Boulder, Colorado); Gavin M King (Columbia, Missouri); Ashley R Carter (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to a method of rapidly and repeatably bringing sharp objects into close proximity to a particular region of interest of a sample with high precision and accuracy in two or three dimensions using a laser guided tip approach with three dimensional registration to the surface. |
| FILED | Thursday, August 05, 2010 |
| APPL NO | 12/806086 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08384614 | Kennedy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy F. Kennedy (Houston, Texas); Patrick W. Fink (Missouri City, Texas); Andrew W. Chu (Houston, Texas); Gregory Y. Lin (Friendswood, Texas) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Timothy F. Kennedy (Houston, Texas); Patrick W. Fink (Missouri City, Texas); Andrew W. Chu (Houston, Texas); Gregory Y. Lin (Friendswood, Texas) |
| ABSTRACT | Apparatus and methods for enhancing the gain of a wireless signal are provided. In at least one specific embodiment, the apparatus can include a screen comprised of one or more electrically conductive regions for reflecting electromagnetic radiation and one or more non-conductive regions for permitting electromagnetic radiation therethrough. The one or more electrically conductive regions can be disposed adjacent to at least one of the one or more non-conductive regions. The apparatus can also include a support member disposed about at least a portion of the screen. The screen can be capable of collapsing by twisting the support member in opposite screw senses to form interleaved concentric sections. |
| FILED | Thursday, September 30, 2010 |
| APPL NO | 12/894749 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/909 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08384630 | Ray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Johnstone Ray (Fountain Hills, Arizona); Mark D. Lowenthal (Gilbert, Arizona); Neil O. Shotton (Perry, Florida); Richard A. Blanchard (Los Altos, California); Mark Allan Lewandowski (Tempe, Arizona); Kirk A. Fuller (Madison, Alabama); Donald Odell Frazier (Huntsville, Alabama) |
| ASSIGNEE(S) | NthDegree Technologies Worldwide Inc (Tempe, Arizona); NASA, an agency of the United States (Washington, District of Columbia) |
| INVENTOR(S) | William Johnstone Ray (Fountain Hills, Arizona); Mark D. Lowenthal (Gilbert, Arizona); Neil O. Shotton (Perry, Florida); Richard A. Blanchard (Los Altos, California); Mark Allan Lewandowski (Tempe, Arizona); Kirk A. Fuller (Madison, Alabama); Donald Odell Frazier (Huntsville, Alabama) |
| ABSTRACT | The present invention provides an electronic apparatus, such as a lighting device comprised of light emitting diodes (LEDs) or a power generating apparatus comprising photovoltaic diodes, which may be created through a printing process, using a semiconductor or other substrate particle ink or suspension and using a lens particle ink or suspension. An exemplary apparatus comprises a base; at least one first conductor; a plurality of diodes coupled to the at least one first conductor; at least one second conductor coupled to the plurality of diodes; and a plurality of lenses suspended in a polymer deposited or attached over the diodes. The lenses and the suspending polymer have different indices of refraction. In some embodiments, the lenses and diodes are substantially spherical, and have a ratio of mean diameters or lengths between about 10:1 and 2:1. The diodes may be LEDs or photovoltaic diodes, and in some embodiments, have a junction formed at least partially as a hemispherical shell or cap. |
| FILED | Tuesday, September 15, 2009 |
| APPL NO | 12/560340 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/82 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385047 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Huikai Xie (Gainsville, Florida); Khai D. T. Ngo (Blacksburg, Virginia) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Huikai Xie (Gainsville, Florida); Khai D. T. Ngo (Blacksburg, Virginia) |
| ABSTRACT | A multi-layer film-stack and method for forming the multilayer film-stack is given where a series of alternating layers of conducting and dielectric materials are deposited such that the conducting layers can be selectively addressed. The use of the method to form integratable high capacitance density capacitors and complete the formation of an integrated power system-on-a-chip device including transistors, conductors, inductors, and capacitors is also given. |
| FILED | Monday, April 02, 2007 |
| APPL NO | 12/295347 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/306.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386121 | Simon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donald L. Simon (Olmsted Falls, Ohio); Sanjay Garg (Westlake, Ohio) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Donald L. Simon (Olmsted Falls, Ohio); Sanjay Garg (Westlake, Ohio) |
| ABSTRACT | A methodology for minimizing the error in on-line Kalman filter-based aircraft engine performance estimation applications is presented. This technique specifically addresses the underdetermined estimation problem, where there are more unknown parameters than available sensor measurements. A systematic approach is applied to produce a model tuning parameter vector of appropriate dimension to enable estimation by a Kalman filter, while minimizing the estimation error in the parameters of interest. Tuning parameter selection is performed using a multi-variable iterative search routine which seeks to minimize the theoretical mean-squared estimation error. Theoretical Kalman filter estimation error bias and variance values are derived at steady-state operating conditions, and the tuner selection routine is applied to minimize these values. The new methodology yields an improvement in on-line engine performance estimation accuracy. |
| FILED | Wednesday, June 02, 2010 |
| APPL NO | 12/791907 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/30.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08381851 | Gray, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles L. Gray, Jr. (Pinckney, Michigan) |
| ASSIGNEE(S) | The United States of America, as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Charles L. Gray, Jr. (Pinckney, Michigan) |
| ABSTRACT | A method for operating a series hybrid vehicle is provided, in which an engine generates secondary power that is either stored or used as direct input energy by a secondary power source to provide motive power to the vehicle. Regenerative braking is used to convert kinetic energy of the vehicle into secondary energy, which is also stored. When the vehicle driver makes a power demand, the secondary power source is powered by secondary energy from an energy storage device, direct input energy generated by the engine, or both, depending on the amount of stored secondary energy in combination with vehicle speed. When in use, the power level at which the engine is operated is also determined on the basis of available stored energy and vehicle speed. At higher vehicle speeds, the amount of stored energy is allowed to be depleted in order to increase the available storage capacity for regenerative braking. |
| FILED | Monday, November 29, 2010 |
| APPL NO | 12/955795 |
| ART UNIT | 3618 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Motor vehicles 180/65.280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383342 | Rublee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Parke A. Rublee (Greensboro, North Carolina); Vincent C. Henrich, III (Greensboro, North Carolina); Michael McClain Marshall (Greensboro, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Greensboro (Greensboro, North Carolina) |
| INVENTOR(S) | Parke A. Rublee (Greensboro, North Carolina); Vincent C. Henrich, III (Greensboro, North Carolina); Michael McClain Marshall (Greensboro, North Carolina) |
| ABSTRACT | Disclosed are compositions, products, methods and systems for monitoring ecosystems, such as bodies of water, for a parameter of the ecosystems, such as the presence or absence of mercury. In one embodiment, the product may include a plurality of oligonucleotides immobilized at known locations on a substrate as an array, such that each location on the array is an oligonucleotide having a sequence derived from a single, predetermined operational taxonomic unit (OTU) and wherein at least one sequence on the array is associated with the presence or absence of mercury. The sequences immobilized on the array may be from known, or unknown organisms. Also disclosed are methods for identifying and isolating bioindicators diagnostic of ecosystem parameters, such as whether mercury is present. The compositions, products, methods and systems of the invention may be used for rapid, and continual monitoring of ecosystems for parameters of interest, such as the presence or absence of mercury. |
| FILED | Friday, October 07, 2011 |
| APPL NO | 13/269041 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383360 | Van de Water et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judy Van de Water (Capay, California); Daniel Braunschweig (Davis, California) |
| ABSTRACT | The present invention provides diagnostic methods for determining the risk of developing an autism spectrum disorder (ASD) in a fetus or child by detecting in a biological sample from the mother antibodies that bind to one or more biomarkers selected from the group consisting of lactate dehydrogenase (LDH), guanine deaminase (GDA), collapsin response mediator protein 1 (CRMP1), stress-induced phosphoprotein 1 (STIP1), alpha subunit of the barbed-end actin binding protein Cap Z (CAPZA2), Y Box Binding Protein 1 (YBX1), eukaryotic translation and elongation factor 1A1 (EEF1A1), microtubule-associated protein Tau (MAPT), dihydropyrimidinase-like protein 2 (DPYSL2), dynamin 1-like protein (DNM1L), radixin (RDX), moesin (MSN), and ezrin (EZR). The invention further provides methods of preventing or reducing the risk of a fetus or child developing an ASD by administering to the mother an agent that blocks the binding of maternal antibodies to the one or more fetal biomarkers listed above or by removing from the mother antibodies that bind to the one or more fetal biomarkers. |
| FILED | Thursday, August 12, 2010 |
| APPL NO | 12/855558 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.920 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 08384035 | Borade et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ramesh B. Borade (Livermore, California); Edith Bourret-Courchesne (Berkeley, California); Stephen E. Derenzo (Pinole, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ramesh B. Borade (Livermore, California); Edith Bourret-Courchesne (Berkeley, California); Stephen E. Derenzo (Pinole, California) |
| ABSTRACT | The present invention provides for a composition comprising an inorganic scintillator comprising a lanthanide-doped barium phosphorous oxide useful for detecting nuclear material. |
| FILED | Monday, October 25, 2010 |
| APPL NO | 12/911583 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/361.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08387122 | Toomim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Toomim (Seattle, Washington); James Fogarty (Seattle, Washington); James Landay (Seattle, Washington); Nathan Morris (Seattle, Washington); Xianhang Zhang (Seattle, Washington); Tadayoshi Kohno (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Michael Toomim (Seattle, Washington); James Fogarty (Seattle, Washington); James Landay (Seattle, Washington); Nathan Morris (Seattle, Washington); Xianhang Zhang (Seattle, Washington); Tadayoshi Kohno (Seattle, Washington) |
| ABSTRACT | Access to resource(s) intended to be shared with specific groups of individuals is controlled using concise tests of shared knowledge instead of (or in addition) to accounts and access control lists. Users can readily learn the concept and choose questions that will control the access by the desired group with little effort. Such questions can be relatively secure to guesses by those not intended to have access, particularly if the number of allowed guesses is relatively limited. Users can generally predict the security of their questions, but sometimes underestimate the ability of attackers to use Web searching or enumeration to discover answers. In such cases, the system can automatically discover weak questions and then suggest alternatives. By lowering the threshold to access control, shared knowledge tests can enable more types of information to acquire collaborative value on the Internet and on other types of networks. |
| FILED | Thursday, May 14, 2009 |
| APPL NO | 12/466242 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Information security 726/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 08381426 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biao Cheng (Edison, New Jersey); Daphne Chang (Montville, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Timothy N Chang (Montville, New Jersey); Biao Cheng (Edison, New Jersey) |
| ABSTRACT | A firing inhibition system for a firearm includes an electromechanical actuator electrically connected to a dynamic grip recognition module including at least one sensor and a microcontroller, wherein the at least one sensor is located in a portion of a firearm operable to receive grip pressure from a user and wherein the at least one sensor is operable to transmit a signal to the microcontroller, wherein the microcontroller is operable to receive programming comprising grip pressure of an authorized user and is operable to interpret whether the grip pressure of the user matches the grip pressure of the authorized user, and to send a signal to the electromechanical actuator to actuate or to not actuate. |
| FILED | Tuesday, March 08, 2011 |
| APPL NO | 13/043035 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/70.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 08384562 | Wall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard W. Wall (Moscow, Idaho); Gabriel DeRuwe (Moscow, Idaho) |
| ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Richard W. Wall (Moscow, Idaho); Gabriel DeRuwe (Moscow, Idaho) |
| ABSTRACT | A mobile traffic controller to aid pedestrians includes a wireless transmitter and receiver that are configured to communicate with a traffic signal or a traffic control system. In response to a user request, the transmitter sends a traffic control request to a traffic signal or a traffic system controller. The request is acknowledged, and when appropriate, the mobile traffic controller receives a message indicating that a crossing is authorized. The mobile controller can include a vibro-tactile or audio output device for communication with the user. In addition, position and orientation systems can be included so that the user can be directed along a preferred path or alerted that a predetermined or legally established passage zone has been exited or is about to be exited. |
| FILED | Wednesday, March 25, 2009 |
| APPL NO | 12/411306 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Communications: Electrical 340/944 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08383116 | Fabene et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paolo Francesco Fabene (Iocalita' Santa Lucia ai Monti, Italy); Eugene C. Butcher (Portola Valley, California); Gabriela Constantin (San Floriano, Italy) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Paolo Francesco Fabene (Iocalita' Santa Lucia ai Monti, Italy); Eugene C. Butcher (Portola Valley, California); Gabriela Constantin (San Floriano, Italy) |
| ABSTRACT | Methods are provided for the prevention and treatment of seizures and epilepsy. It is shown herein that leukocyte recruitment plays a key role in the pathogenesis of epilepsy. Treatment with an agent that inhibits leukocyte recruitment has therapeutic and preventative effects in blocking recurrent seizures and epilepsy. |
| FILED | Tuesday, October 13, 2009 |
| APPL NO | 12/587879 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/139.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 08386485 | Kerschberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Larry Kerschberg (Fairfax, Virginia); Wooju Kim (Seoul, South Korea); Hanjo Jeong (Fairfax, Virginia); Yong Uk Song (Kangwon, South Korea) |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Larry Kerschberg (Fairfax, Virginia); Wooju Kim (Seoul, South Korea); Hanjo Jeong (Fairfax, Virginia); Yong Uk Song (Kangwon, South Korea) |
| ABSTRACT | A service-oriented system architecture includes a computer-implemented search method and computer-implemented agent system for enabling efficient information searches on, for example, on XML databases, relational databases, and files located on intranets, the Internet, or other computer network systems. Referred to as the Knowledge Sifter architecture, the architecture may comprise, in one embodiment, a community of cooperating agents. The system architecture may be employed using a variety of methodologies, such as a case-based framework, collaborative filtering, or hybrid filtering. The case-based framework may be configured to recommend query specifications and refinements based on previously-stored user-query cases. Collaborative filtering involves the architecture recommending a set of unseen items that are preferred by other users to the active user. Hybrid filtering combines collaborative filtering and content-based filtering. |
| FILED | Friday, July 31, 2009 |
| APPL NO | 12/533226 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/736 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 08385685 | Bedros et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Saad J. Bedros (West St. Paul, Minnesota); Jana Trojanova (Prague, Czech Republic) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Saad J. Bedros (West St. Paul, Minnesota); Jana Trojanova (Prague, Czech Republic) |
| ABSTRACT | A system and method include decomposing via a computer an ocular region into several filtered images of different orientation and scale, using the computer to combine the decomposed images for each scale, using a computer executed classifier for each scale, matching across different quality images, and using a computer, constructing a matching score by combining the scale scores using adaptively weighted sum for each scale. |
| FILED | Wednesday, June 08, 2011 |
| APPL NO | 13/155548 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/284 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08383342 | Rublee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Parke A. Rublee (Greensboro, North Carolina); Vincent C. Henrich, III (Greensboro, North Carolina); Michael McClain Marshall (Greensboro, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Greensboro (Greensboro, North Carolina) |
| INVENTOR(S) | Parke A. Rublee (Greensboro, North Carolina); Vincent C. Henrich, III (Greensboro, North Carolina); Michael McClain Marshall (Greensboro, North Carolina) |
| ABSTRACT | Disclosed are compositions, products, methods and systems for monitoring ecosystems, such as bodies of water, for a parameter of the ecosystems, such as the presence or absence of mercury. In one embodiment, the product may include a plurality of oligonucleotides immobilized at known locations on a substrate as an array, such that each location on the array is an oligonucleotide having a sequence derived from a single, predetermined operational taxonomic unit (OTU) and wherein at least one sequence on the array is associated with the presence or absence of mercury. The sequences immobilized on the array may be from known, or unknown organisms. Also disclosed are methods for identifying and isolating bioindicators diagnostic of ecosystem parameters, such as whether mercury is present. The compositions, products, methods and systems of the invention may be used for rapid, and continual monitoring of ecosystems for parameters of interest, such as the presence or absence of mercury. |
| FILED | Friday, October 07, 2011 |
| APPL NO | 13/269041 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08383520 | Marrs |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Marrs (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Michael Marrs (Phoenix, Arizona) |
| ABSTRACT | In some embodiments, a method of etching an organosiloxane dielectric material can include: (a) providing the organosiloxane dielectric material; (b) providing a patterned mask over the organosiloxane dielectric material; and (c) reactive ion etching the organosiloxane dielectric material. Other embodiments are disclosed in this application. |
| FILED | Friday, May 27, 2011 |
| APPL NO | 13/118240 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/710 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08382194 | Wood |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard M. Wood (Virginia Beach, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard M. Wood (Virginia Beach, Virginia) |
| ABSTRACT | An improved method and device for the reduction of aerodynamic drag and for improved performance of vehicles by increasing the pressure on the base of the trailing vehicle or vehicle component by controlling the boundary layer as it exists the vehicle trailing edge. The subject invention consists of a multiple panels located near the base area of a bluff base vehicle. The flow control objectives are accomplished by positioning minimally sized panels comprising the invention in close proximity to the side and top surfaces of the vehicle, where the leading edge of each panel is positioned in close proximity to the trailing edge of the vehicle. The side panels comprising the invention are laterally positioned outboard of the side surface of the vehicle. The top panels are vertically positioned above the top surface of the vehicle. |
| FILED | Friday, March 06, 2009 |
| APPL NO | 12/381049 |
| ART UNIT | 3612 — Material and Article Handling |
| CURRENT CPC | Land vehicles: Bodies and tops 296/180.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08383597 | Huang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xin-Yun Huang (New York, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Xin-Yun Huang (New York, New York) |
| ABSTRACT | The invention provides an agent that reduces the expression of Gα12 or Gα13 polypeptide, as well as an agent that enhances G protein Gα12 or Gα13 expression and/or activity. An agent of the invention may be used to decrease or increase G protein Gα12 or Gα13 expression and/or activity thereby to treat or prevent the onset of a disease or condition associated with Gα12 or Gα13 expression and/or activity. The invention also provides a method for screening for an anti-cancer or anti-angiogenesis agent, as well as an agent that promotes angiogenesis. |
| FILED | Thursday, May 24, 2007 |
| APPL NO | 11/805715 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08385101 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jianhua Yang (Palo Alto, California); Minxian Max Zhang (Mountain View, California); R. Stanley Williams (Portola Valley, California) |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Jianhua Yang (Palo Alto, California); Minxian Max Zhang (Mountain View, California); R. Stanley Williams (Portola Valley, California) |
| ABSTRACT | Methods and means related to memory resistors are provided. A memristor includes at least two different active materials disposed between a pair of electrodes. The active materials are selected to exhibit respective and opposite changes in electrical resistance in response to changes in oxygen ion content. The active materials are subject to oxygen ion reconfiguration under the influence of an applied electric field. An electrical resistance of the memristor is thus adjustable by way of applied programming voltages and is non-volatile between programming events. |
| FILED | Friday, July 30, 2010 |
| APPL NO | 12/847874 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/148 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08386849 | Shao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Qingqiu Ginger Shao (Oro Valley, Arizona); Randy R. Magnuson (Scottsdale, Arizona); Dave Miller (Minneapolis, Minnesota); Bradley John Barton (Albuquerque, New Mexico); David Michael Kolbet (Scottsdale, Arizona) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Qingqiu Ginger Shao (Oro Valley, Arizona); Randy R. Magnuson (Scottsdale, Arizona); Dave Miller (Minneapolis, Minnesota); Bradley John Barton (Albuquerque, New Mexico); David Michael Kolbet (Scottsdale, Arizona) |
| ABSTRACT | A method of detecting and diagnosing system faults, includes detecting the noisy status of a monitor during operations and incorporating a quantified monitor uncertainty level to support fault isolation reasoning. A sequential probability ratio test is used to statistically test the noisy status of a monitor and Shannon's entropy theory is used to quantify the uncertainty levels of the monitor to support the use of the monitor values in fault isolation. |
| FILED | Friday, January 29, 2010 |
| APPL NO | 12/696877 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
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This week's information is published in the FedInvent Patents report for Tuesday, February 26, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130226.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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