FedInvent™ Patents

Patent Details for Tuesday, March 19, 2013

This page was updated on Monday, March 27, 2023 at 03:45 AM GMT

Department of Defense (DOD)

08397418 — System for providing electrical power to accessories mounted on the powered

US 08397418	Cabahug et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Eric F. Cabahug (Fairfax, Virginia); Joseph Frascati (Arlington, Virginia); Don McLaughlin (Ashburn, Virginia); James S. Dodd (Linden, Virginia); Ben Feldman (Reston, Virginia)
ASSIGNEE(S)	Prototype Productions Incorporated Ventures Two, LLC (Ashburn, Virginia)
INVENTOR(S)	Eric F. Cabahug (Fairfax, Virginia); Joseph Frascati (Arlington, Virginia); Don McLaughlin (Ashburn, Virginia); James S. Dodd (Linden, Virginia); Ben Feldman (Reston, Virginia)
ABSTRACT	A firearm may have a plurality of power-consuming accessories that can be attached to the weapon. In order to reduce the weight of these power-consuming accessories, as well as the proliferation of their batteries, the Weapon Accessory Power Distribution System provides a common power source to power the power-consuming accessories attached to the weapon. One or more powered rails are provided to provide a point of electrical interconnection for the power-consuming accessories, absent the use of connectors with their tethering cables, which are susceptible to entanglement. The powered rail(s) are electrically interconnected with a power source, which typically is a battery mounted in the butt stock of the weapon.
FILED	Wednesday, March 30, 2011
APPL NO	13/075857
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Firearms 042/85
VIEW PATENT	@ USPTO: Full Text PDF

08397520 — Phase shift devices for pulse tube coolers

US 08397520	Yuan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	Sidney W. K. Yuan (Los Angeles, California); Ed Fong (Oakland, California); David G. T. Curran (Pacific Palisades, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Sidney W. K. Yuan (Los Angeles, California); Ed Fong (Oakland, California); David G. T. Curran (Pacific Palisades, California)
ABSTRACT	Various embodiments are directed to pulse tube coolers and components thereof. A pulse tube cooler may comprise a compressor, a regenerator, a pulse tube and a reservoir. A network of phase control devices may be placed in a fluid path between a hot end of the pulse tube and the reservoir. The network of phase control devices may have at least one flow resistance device and at least one inertance device.
FILED	Tuesday, November 03, 2009
APPL NO	12/611764
ART UNIT	3744 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Refrigeration 062/6
VIEW PATENT	@ USPTO: Full Text PDF

08397568 — Bias measurement for MEMS gyroscopes and accelerometers

US 08397568	Cardarelli
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Donato Cardarelli (Medfield, Massachusetts)
ASSIGNEE(S)	Milli Sensor Systems+Actuators (West Newton, Massachusetts)
INVENTOR(S)	Donato Cardarelli (Medfield, Massachusetts)
ABSTRACT	A system and method for separating bias instability of MEMS inertial instruments such as gyroscopes or accelerometers from the instrument signal, in which the inertial measurement instrument has an input axis and an output signal, and the bias instability has a frequency. The instrument is rotated about a rotation axis that is orthogonal to the input axis, at a frequency that is greater than the bias instability frequency. The instrument output signal is detected, and demodulated with a phase-sensitive detection method referenced to the instrument rotation.
FILED	Tuesday, April 24, 2007
APPL NO	11/739485
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/504.120
VIEW PATENT	@ USPTO: Full Text PDF

08397608 — Glow plug removal tool

US 08397608	Dumback
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Christopher F. Dumback (Scranton, New Jersey)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Christopher F. Dumback (Scranton, New Jersey)
ABSTRACT	A hand tool for removing a glow plug from a combustion engine includes two interconnected arms each being movable with respect to one another and each having a working end and an opposing handle portion. The hand tool may further include an extension body that has a generally tubular configuration. The extension body may have a first body portion and a second body portion wherein the first body portion extends from one of the interconnected arms and wherein the second body portion extends from the other of the interconnected arms and wherein each of the first body portion and the second body portion includes an interior surface that is threaded.
FILED	Friday, May 21, 2010
APPL NO	12/800817
ART UNIT	3727 — Printing/Measuring and Testing
CURRENT CPC	Tools 081/426.500
VIEW PATENT	@ USPTO: Full Text PDF

08397622 — Bi-directional ammunition lifter

US 08397622	Fowler, IV et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Robert J. Fowler, IV (Fredericksburg, Virginia); Carter G. Timberlake (Colonial Beach, Virginia); Michael M. Canaday (King George, Virginia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert J. Fowler, IV (Fredericksburg, Virginia); Carter G. Timberlake (Colonial Beach, Virginia); Michael M. Canaday (King George, Virginia)
ABSTRACT	An ammunition elevator device is provided for raising and lowering ammunition. The device includes a housing, a crank assembly, a pawl mechanism, and a transfer linkage. The housing has a chamber flanked by first and second flanges. The assembly includes a crank axle, first and second sprockets mounted to the axle for elevating the ammunition, and a ratchet gear mounted to the axle adjacent to the first flange. The pawl mechanism includes a pawl, a toggle and a pin spreader. The transfer linkage has a rotatable bar pivotably connected to the second flange, a rod that radially shifts relative to the crank axle in response to the sprockets, and a pair of rotatable joints. The ratchet gear connects to the axle adjacent the first flange, wherein the gear cyclically pivots the pawl for raising the toggle.
FILED	Wednesday, May 25, 2011
APPL NO	13/134485
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ordnance 089/46
VIEW PATENT	@ USPTO: Full Text PDF

08397656 — Method of steering a craft

US 08397656	Purdy et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	David Purdy (Oxnard, California); Chris Vandergeugten (Santa Paula, California); Douglas O'Neill (Vallejo, California); Dustin Draper (Ventura, California); Evan Harriger (Ventura, California); Mark Seal (Camarillo, California)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	David Purdy (Oxnard, California); Chris Vandergeugten (Santa Paula, California); Douglas O'Neill (Vallejo, California); Dustin Draper (Ventura, California); Evan Harriger (Ventura, California); Mark Seal (Camarillo, California)
ABSTRACT	A method of towing a craft having a fore rudder and rear rudder using a towing vehicle with the fore rudder and rear rudder initially oriented parallel to the length of the craft such that the craft follows directly behind the towing vehicle. The fore rudder is rotated to a position less than 90 degrees off parallel to the length of the craft. The rear rudder is rotated in an opposite direction to the fore rudder and to a position less than 90 degrees off parallel to the length of the craft, causing the craft to move off to the side of the track of the towing vehicle while the craft maintains movement substantially parallel to the towing vehicle, producing an of offset tow.
FILED	Wednesday, February 10, 2010
APPL NO	12/703562
ART UNIT	3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ships 114/244
VIEW PATENT	@ USPTO: Full Text PDF

08397974 — Self-reacting friction stir welding tool with the ability to add filler material

US 08397974	Schultz et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Jeffrey Patrick Schultz (Blacksburg, Virginia); Kevin Creehan (Blacksburg, Virginia)
ASSIGNEE(S)	Aeroprobe Corporation (Blacksburg, Virginia)
INVENTOR(S)	Jeffrey Patrick Schultz (Blacksburg, Virginia); Kevin Creehan (Blacksburg, Virginia)
ABSTRACT	The present invention relates to tools and methods for welding, coating, repairing, or otherwise modifying the surface of a metal substrate. More specifically, embodiments of the present invention provide self-reacting friction stir welding tools which have an internal channel that allows filler materials to be added to the weld joint or otherwise friction stir processed area. Embodiments also provide friction stir tooling having upper and lower shoulders disposed at a fixed distance from one another and connected by a fixed split-pin. The tooling can be configured for automatically dispensing varying amounts of filler material into the tooling in response to variations in thickness of a substrate being processed.
FILED	Monday, April 09, 2012
APPL NO	13/442285
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Metal fusion bonding 228/2.100
VIEW PATENT	@ USPTO: Full Text PDF

08398038 — Wheel support

US 08398038	Shimmel et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Jeffrey T. Shimmel (Solsberry, Indiana); James G. Buechler (Jasper, Indiana); Michael L. Holzmeyer (Bloomfield, Indiana)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jeffrey T. Shimmel (Solsberry, Indiana); James G. Buechler (Jasper, Indiana); Michael L. Holzmeyer (Bloomfield, Indiana)
ABSTRACT	A wheel support assembly is mounted to a pivotable system spanning an opening, with the pivotable system mounted to one side of the opening at a pivotable connection and to another side of the opening at a removable connection. The support assembly is disposed proximate the removable connection and spaced apart from the pivotable connection, and has a wheel positioned and oriented to support the pivotable system weight that would otherwise be cantilevered as the pivotable system rotates about the pivotable support. The wheel support assembly may include a vertically adjustable wheel that may be adjusted to remain just out of contact with the support surface when the pivotable assembly is connected to both the pivotable and the removable connections.
FILED	Monday, November 30, 2009
APPL NO	12/627965
ART UNIT	3632 — Static Structures, Supports and Furniture
CURRENT CPC	Supports 248/185.100
VIEW PATENT	@ USPTO: Full Text PDF

08398109 — Heavy-duty trailer

US 08398109	Amrine, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)	James M. Amrine, Jr. (Ann Arbor, Michigan); David Coates (Washington, Michigan)
ASSIGNEE(S)	Altair Engineering, Inc. (Troy, Michigan)
INVENTOR(S)	James M. Amrine, Jr. (Ann Arbor, Michigan); David Coates (Washington, Michigan)
ABSTRACT	A heavy duty wheeled trailer for use in towing the trailer behind a vehicle. The trailer includes an adjustable height tow connection point to adjust and connect to different types of tow vehicles while maintaining the front deck substantially parallel to the trailer main deck. The trailer further includes a modular support frame allowing the trailer to be easily scaled in length and performance capabilities through removal or addition of modular frame cells.
FILED	Tuesday, January 11, 2011
APPL NO	13/004417
ART UNIT	3611 — Static Structures, Supports and Furniture
CURRENT CPC	Land vehicles 280/441.200
VIEW PATENT	@ USPTO: Full Text PDF

08398347 — Integrated nutplate and clip for a floating fastener and method of manufacture and assembly

US 08398347	Woodall et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Wayne K. Woodall (Oro Valley, Arizona); Walter S. Pope (Tucson, Arizona); E. Russ Althof (Tucson, Arizona); Scott A. Muse (Tucson, Arizona)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Wayne K. Woodall (Oro Valley, Arizona); Walter S. Pope (Tucson, Arizona); E. Russ Althof (Tucson, Arizona); Scott A. Muse (Tucson, Arizona)
ABSTRACT	An inexpensive and reliable floating fastener is provided by manufacturing an integrated nutplate into the backside of the interior structural member. A retention clip engages the nutplate to capture the nut while allowing the nut to float. The integrated nutplate roughly aligns the floating nut to the axial through-hole in the structural member and provides the torque resistance required to drive the screw into the nut. The retention clip holds the nut in place and provides the axial resistance required for the lead chamfer of the screw to engage the nut and resist the axial loading on the screw during installation. The nutplate is designed to facilitate cost-effective manufacturing. The per hole cost of the integrated floating-fastener is approximately 30% of the cost of the industry standard riveted floating fastener.
FILED	Thursday, December 16, 2010
APPL NO	12/970051
ART UNIT	3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Expanded, threaded, driven, headed, tool-deformed, or locked-threaded fastener 411/85
VIEW PATENT	@ USPTO: Full Text PDF

08398570 — Wide band vibrational stimulus device

US 08398570	Mortimer et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Warfare Center (NAWC)
APPLICANT(S)	Bruce J. P. Mortimer (Maitland, Florida); Gary A. Zets (Maitland, Florida)
ASSIGNEE(S)	Engineering Acoustics, Inc. (Casselberry, Florida)
INVENTOR(S)	Bruce J. P. Mortimer (Maitland, Florida); Gary A. Zets (Maitland, Florida)
ABSTRACT	An eccentric mass (EM) motor in a vibrotactile transducer provides a wide band vibrational stimulus to a mechanical load in response to an electrical input. The eccentric mass and motor may form part of the transducer actuator moving mass, which is in contact with a load, i.e, the skin of a user. The moving mass and the actuator housing may be in simultaneous contact with the load. The moving mass may be guided by a spring between the actuator housing and the moving mass. The load, moving mass, spring compliance, and housing mass make up a moving mass resonant system. The spring compliance and system component masses may be configured to maximize the actuator displacement and/or tailor the transducer response to a desired level. This configuration may be implemented as a low-mass wearable wide-band vibrotactile transducer.
FILED	Monday, January 05, 2009
APPL NO	12/348800
ART UNIT	3778 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Surgery: Kinesitherapy 61/46
VIEW PATENT	@ USPTO: Full Text PDF

08398935 — Sheath flow device and method

US 08398935	Howell, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Peter B. Howell, Jr. (Gaithersburg, Maryland); Frances S. Ligler (Potomac, Maryland); Adam R. Shields (Alexandria, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S)	Peter B. Howell, Jr. (Gaithersburg, Maryland); Frances S. Ligler (Potomac, Maryland); Adam R. Shields (Alexandria, Virginia)
ABSTRACT	A sheath flow system having a channel with at least one fluid transporting structure located in the top and bottom surfaces situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. A wide variety of shapes of fibers and other materials can be produced from this system through the use of polymerizable material.
FILED	Thursday, April 07, 2011
APPL NO	13/081688
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/503
VIEW PATENT	@ USPTO: Full Text PDF

08399057 — Ordered vertically oriented porous inorganic films produced through solution processing

US 08399057	Tolbert et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Sarah H. Tolbert (Los Angeles, California); Erik K. Richman (Gibsonia, Pennsylvania)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Sarah H. Tolbert (Los Angeles, California); Erik K. Richman (Gibsonia, Pennsylvania)
ABSTRACT	Porous films with straight pores oriented normal to the plane of the films are produced through solution processing techniques. The production takes advantage of inorganic-surfactant or inorganic-polymer co-assembly and a patterned substrate. The patterned substrate, which is also produced via solution phase self-assembly, forces vertical orientation in a hexagonal cylinder system with no practical limits in substrate size or type. This provides a route to vertically oriented inorganic pores with a pitch ranging from 3 nm to over 15 nm and pore sizes ranging from 2 nm to over 12 nm. The size is tuned by choice the choice of organic templating agents and the deposition conditions. The pores can be produced with or without a capping layer which can be used to seal the nanopores.
FILED	Thursday, June 08, 2006
APPL NO	11/449465
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/271
VIEW PATENT	@ USPTO: Full Text PDF

08399336 — Method for fabricating a 3D integrated circuit device having lower-cost active circuitry layers stacked before higher-cost active circuitry layer

US 08399336	Farooq et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Mukta G. Farooq (Hopewell Junction, New York); Robert Hannon (Wappingers Falls, New York); Subramanian S. Iyer (Mount Kisco, New York); Steven J. Koester (Ossining, New York); Fei Liu (Mount Kisco, New York); Sampath Purushothaman (Yorktown Heights, New York); Albert M. Young (Fishkill, New York); Roy R. Yu (Poughkeepsie, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Mukta G. Farooq (Hopewell Junction, New York); Robert Hannon (Wappingers Falls, New York); Subramanian S. Iyer (Mount Kisco, New York); Steven J. Koester (Ossining, New York); Fei Liu (Mount Kisco, New York); Sampath Purushothaman (Yorktown Heights, New York); Albert M. Young (Fishkill, New York); Roy R. Yu (Poughkeepsie, New York)
ABSTRACT	A method is provided for fabricating a 3D integrated circuit structure. According to the method, a first active circuitry layer wafer that includes active circuitry is provided, and a first portion of the first active circuitry layer wafer is removed such that a second portion of the first active circuitry layer wafer remains. Another wafer that includes active circuitry is provided, and the other wafer is bonded to the second portion of the first active circuitry layer wafer. The first active circuitry layer wafer is lower-cost than the other wafer. Also provided are a tangible computer readable medium encoded with a program for fabricating a 3D integrated circuit structure, and a 3D integrated circuit structure.
FILED	Tuesday, August 19, 2008
APPL NO	12/194211
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/455
VIEW PATENT	@ USPTO: Full Text PDF

08399339 — Nanosensors

US 08399339	Lieber et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF)
APPLICANT(S)	Charles M. Lieber (Lexington, Massachusetts); Hongkun Park (Lexington, Massachusetts); Qingqiao Wei (Corvallis, Oregon); Yi Cui (Sunnyvale, California); Wenjie Liang (Oakland, California)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Charles M. Lieber (Lexington, Massachusetts); Hongkun Park (Lexington, Massachusetts); Qingqiao Wei (Corvallis, Oregon); Yi Cui (Sunnyvale, California); Wenjie Liang (Oakland, California)
ABSTRACT	Electrical devices comprised of nanowires are described, along with methods of their manufacture and use. The nanowires can be nanotubes and nanowires. The surface of the nanowires may be selectively functionalized Nanodetector devices are described.
FILED	Monday, April 11, 2011
APPL NO	13/083817
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/478
VIEW PATENT	@ USPTO: Full Text PDF

08399383 — Protein chips for high throughput screening of protein activity

US 08399383	Snyder et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Michael Snyder (Fairfield, Connecticut); Mark Reed (Monroe, Connecticut); Heng Zhu (New Haven, Connecticut); James Frank Klemic (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Michael Snyder (Fairfield, Connecticut); Mark Reed (Monroe, Connecticut); Heng Zhu (New Haven, Connecticut); James Frank Klemic (New Haven, Connecticut)
ABSTRACT	The present invention relates to protein chips useful for the large-scale study of protein function where the chip contains densely packed reaction wells. The invention also relates to methods of using protein chips to assay simultaneously the presence, amount, and/or function of proteins present in a protein sample or on one protein chip, or to assay the presence, relative specificity, and binding affinity of each probe in a mixture of probes for each of the proteins on the chip. The invention also relates to methods of using the protein chips for high density and small volume chemical reactions. Also, the invention relates to polymers useful as protein chip substrates and methods of making protein chips. The invention further relates to compounds useful for the derivatization of protein chip substrates.
FILED	Friday, May 04, 2001
APPL NO	09/849781
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Combinatorial chemistry technology: Method, library, apparatus 56/14
VIEW PATENT	@ USPTO: Full Text PDF

08399434 — Method of activation of oxazaphosphorines

US 08399434	Spasojevic et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) U.S. Public Health Service (USPHS)
APPLICANT(S)	Ivan Spasojevic (Durham, North Carolina); Michael O. Colvin (Chapel Hill, North Carolina); Ines Batinic-Haberle (Durham, North Carolina); Susan M. Ludeman (Delmar, New York); Michael P. Gamcsik (Chapel Hill, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Ivan Spasojevic (Durham, North Carolina); Michael O. Colvin (Chapel Hill, North Carolina); Ines Batinic-Haberle (Durham, North Carolina); Susan M. Ludeman (Delmar, New York); Michael P. Gamcsik (Chapel Hill, North Carolina)
ABSTRACT	The present invention provides a method of hydroxylating or oxidizing a compound of interest in a subject (e.g., a cytotoxic oxazaphosphorine prodrug), by administering the compound of interest to the subject; and concurrently administering the subject a metalloporphyrin in an amount effective to hydroxylate or oxidize the compound of interest in the subject.
FILED	Tuesday, November 06, 2007
APPL NO	12/375482
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/90
VIEW PATENT	@ USPTO: Full Text PDF

08399502 — Analogs of indole-3-carbinol and their use as agents against infection

US 08399502	Jong et al.
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Ling Jong (Sunnyvale, California); Faming Jiang (Castro Valley, California); Gaoquan Li (Mountain View, California); Kristien Mortelmans (Los Altos Hills, California)
ASSIGNEE(S)	SRI International (Menlo Park, California)
INVENTOR(S)	Ling Jong (Sunnyvale, California); Faming Jiang (Castro Valley, California); Gaoquan Li (Mountain View, California); Kristien Mortelmans (Los Altos Hills, California)
ABSTRACT	Compounds useful as antibacterial agents are provided. The compounds are analogs of indole-3-carbinol and have a backbone selected from dihydroindolo[2,3-b]carbazole, 2,2′-diindolylmethane, 2′,3-diindolylmethane, and 3,3′-diindolylmethane. The compounds are useful therapeutic and prophylactic treatment of bacterial infections in mammals. Methods of synthesis of the compounds are provided, as are pharmaceutical compositions containing the compounds.
FILED	Tuesday, June 26, 2012
APPL NO	13/533910
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/410
VIEW PATENT	@ USPTO: Full Text PDF

08399603 — Cathodically coloring yellow soluble electrochromic and light emitting polymers

US 08399603	Amb et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Chad Martin Amb (Midland, Michigan); Justin Adam Kerszulis (Gainesville, Florida); John R. Reynolds (Gainesville, Florida); Aubrey Lynn Dyer (Gainesville, Florida); Emily Thompson (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Chad Martin Amb (Midland, Michigan); Justin Adam Kerszulis (Gainesville, Florida); John R. Reynolds (Gainesville, Florida); Aubrey Lynn Dyer (Gainesville, Florida); Emily Thompson (Gainesville, Florida)
ABSTRACT	Embodiments of the invention are directed to yellow-to-transmissive conjugated polymers, a method to prepare the yellow conjugated polymers, the use of the yellow conjugated polymers in an electrochromic and/or electroluminescent device comprising neutral state primary subtractive colored conjugated polymers, and a method to prepare the device comprising the yellow conjugated polymer. The yellow conjugated polymers comprise a sequence of dioxythiophene units alternating with aromatic units, thiophene units, furan units, and/or pyrrole units. The yellow conjugated polymers are prepared by cross-condensation reactions. The yellow conjugated polymers can be soluble and preparation of the device involves deposition of the yellow conjugated polymer from solution onto a surface.
FILED	Thursday, October 27, 2011
APPL NO	13/282999
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 528/377
VIEW PATENT	@ USPTO: Full Text PDF

08399604 — Sulfonation of conducting polymers and OLED, photovoltaic, and ESD devices

US 08399604	Seshadri et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Venkataramanan Seshadri (Pittsburgh, Pennsylvania); Brian E. Woodworth (Pittsburgh, Pennsylvania); Christopher Greco (Pittsburgh, Pennsylvania); Darin Laird (Pittsburgh, Pennsylvania); Mathew K. Mathai (Monroeville, Pennsylvania)
ASSIGNEE(S)	Plextronics, Inc. (Pittsburgh, Pennsylvania)
INVENTOR(S)	Venkataramanan Seshadri (Pittsburgh, Pennsylvania); Brian E. Woodworth (Pittsburgh, Pennsylvania); Christopher Greco (Pittsburgh, Pennsylvania); Darin Laird (Pittsburgh, Pennsylvania); Mathew K. Mathai (Monroeville, Pennsylvania)
ABSTRACT	Conducting polymer systems for hole injection or transport layer applications including a composition comprising: a water soluble or water dispersible regioregular polythiophene comprising (i) at least one organic substituent, and (ii) at least one sulfonate substituent comprising sulfonate sulfur bonding directly to the polythiophene backbone. The polythiophene can be water soluble, water dispersible, or water swellable. They can be self-doped. The organic substituent can be an alkoxy substituent, or an alkyl substituent. OLED, PLED, SMOLED, PV, and ESD applications can be used.
FILED	Friday, August 12, 2011
APPL NO	13/209210
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 528/391
VIEW PATENT	@ USPTO: Full Text PDF

08399688 — Production of levulinic acid, furfural, and gamma valerolactone from C₅and C₆carbohydrates in mono- and biphasic systems using gamma-valerolactone as a solvent

US 08399688	Dumesic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	James A. Dumesic (Verona, Wisconsin); David Martin Alonso (Madison, Wisconsin); Elif I. Gürbüz (Madison, Wisconsin); Stephanie G. Wettstein (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	James A. Dumesic (Verona, Wisconsin); David Martin Alonso (Madison, Wisconsin); Elif I. Gürbüz (Madison, Wisconsin); Stephanie G. Wettstein (Madison, Wisconsin)
ABSTRACT	A method to make levulinic acid (LA), furfural, or gamma-valerolactone (GVL). React cellulose (and/or other C₆carbohydrates) or xylose (and/or other C₅carbohydrates) or combinations thereof in a monophasic reaction medium comprising GVL and an acid; or (ii) a biphasic reaction system comprising an organic layer comprising GVL, and a substantially immiscible aqueous layer. At least a portion of the cellulose (and/or other C₆carbohydrates), if present, is converted to LA and at least a portion of the xylose (and/or other C₅carbohydrates), if present, is converted into furfural.
FILED	Thursday, April 12, 2012
APPL NO	13/445643
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Organic compounds 549/326
VIEW PATENT	@ USPTO: Full Text PDF

08399751 — Functional abiotic nanosystems

US 08399751	Lu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Siyuan Lu (Los Angeles, California); Anupam Madhukar (Arcadia, California); Mark S. Humayun (Glendale, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Siyuan Lu (Los Angeles, California); Anupam Madhukar (Arcadia, California); Mark S. Humayun (Glendale, California)
ABSTRACT	The invention relates to imparting photoreactivity to target cells, e.g., retinal cells, by introducing photoresponsive functional abiotic nanosystems (FANs), nanometer-scale semiconductor/metal or semiconductor/semiconductor hetero-junctions that in this case include a photovoltaic effect. The invention further provides methods of making and using FANs, where the hetero-junctions bear surface functionalization that localizes them in cell membranes. Illumination of these hetero-junctions incorporated in cell membranes generates photovoltages that depolarize the membranes, such as those of nerve cells, in which FANs photogenerate action potentials. Incorporating FANs into the cells of a retina with damaged photoreceptor cells reintroduces photoresponsiveness to the retina, so that light creates action potentials that the brain interprets as sight.
FILED	Thursday, June 12, 2008
APPL NO	12/138289
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Nanotechnology 977/925
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08399761 — Organic photovoltaic device with interfacial layer and method of fabricating same

US 08399761	Marks et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE)
APPLICANT(S)	Tobin J. Marks (Evanston, Illinois); Alexander W. Hains (Lakewood, Colorado)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Tobin J. Marks (Evanston, Illinois); Alexander W. Hains (Lakewood, Colorado)
ABSTRACT	An organic photovoltaic device and method of forming same. In one embodiment, the organic photovoltaic device has an anode, a cathode, an active layer disposed between the anode and the cathode; and an interfacial layer disposed between the anode and the active layer, the interfacial layer comprising 5,5′-bis[(p-trichlorosilylpropylphenyl)phenylamino]-2,2′-bithiophene (PABTSi₂).
FILED	Friday, April 30, 2010
APPL NO	12/771376
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Batteries: Thermoelectric and photoelectric 136/263
VIEW PATENT	@ USPTO: Full Text PDF

08399817 — Micro designator dart

US 08399817	Rayms-Keller et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Alfredo N. Rayms-Keller (Fredericksburg, Virginia); Francisco Santiago (Fredericksburg, Virginia); Victor H. Gehman, Jr. (Dahlgren, Virginia); Karen J. Long (Upper Marlboro, Maryland); Kevin A. Boulais (Waldorf, Maryland); Peter L. Wick (Fredericksburg, Virginia); Alexander Strugatsky (King George, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Alfredo N. Rayms-Keller (Fredericksburg, Virginia); Francisco Santiago (Fredericksburg, Virginia); Victor H. Gehman, Jr. (Dahlgren, Virginia); Karen J. Long (Upper Marlboro, Maryland); Kevin A. Boulais (Waldorf, Maryland); Peter L. Wick (Fredericksburg, Virginia); Alexander Strugatsky (King George, Virginia)
ABSTRACT	A micro designator dart engages a target to allow for designation and tracking of the target by transmitting a radio-frequency identification code. The housing of the micro designator dart is configured to enclose its components and deform upon impact with a target to allow a target-engaging member to physically attach the micro designator dart to the target. Also upon impact with the target, an impact-sensitive triggering mechanism in the micro designator dart activates a power source, causing a transmitter to send a predetermined coded infrared signal to the seeker unit of a precision guided munitions system. The micro designator dart may also include a self-destruct device.
FILED	Friday, August 12, 2011
APPL NO	13/136903
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeronautics and astronautics 244/3.160
VIEW PATENT	@ USPTO: Full Text PDF

08399845 — Neutron detector cell efficiency

US 08399845	Fechner et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL)
APPLICANT(S)	Paul S. Fechner (Morristown, New Jersey); David O. Erstad (Morristown, New Jersey); Todd A. Randazzo (Morristown, New Jersey); Bradley J. Larsen (Morristown, New Jersey)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	Paul S. Fechner (Morristown, New Jersey); David O. Erstad (Morristown, New Jersey); Todd A. Randazzo (Morristown, New Jersey); Bradley J. Larsen (Morristown, New Jersey)
ABSTRACT	Neutron detection cells and corresponding methods of detecting charged particles that make efficient use of silicon area are set forth. Three types of circuit cells/arrays are described: state latching circuits, glitch generating cells, and charge loss circuits. An array of these cells, used in conjunction with a neutron conversion film, increases the area that is sensitive to a strike by a charged particle over that of an array of SRAM cells. The result is a neutron detection cell that uses less power, costs less, and is more suitable for mass production.
FILED	Monday, March 19, 2012
APPL NO	13/424269
ART UNIT	2884 — Optics
CURRENT CPC	Radiant energy 250/370.50
VIEW PATENT	@ USPTO: Full Text PDF

08399939 — Color selective photodetector and methods of making

US 08399939	Walker et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE)
APPLICANT(S)	Brian J. Walker (Somerville, Massachusetts); August Dorn (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Brian J. Walker (Somerville, Massachusetts); August Dorn (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts)
ABSTRACT	A photoelectric device, such as a photodetector, can include a semiconductor nanowire electrostatically associated with a J-aggregate. The J-aggregate can facilitate absorption of a desired wavelength of light, and the semiconductor nanowire can facilitate charge transport. The color of light detected by the device can be chosen by selecting a J-aggregate with a corresponding peak absorption wavelength.
FILED	Friday, December 03, 2010
APPL NO	12/960090
ART UNIT	2891 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/414
VIEW PATENT	@ USPTO: Full Text PDF

08399941 — Magnetic junction elements having an easy cone anisotropy and a magnetic memory using such magnetic junction elements

US 08399941	Apalkov et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Dmytro Apalkov (San Jose, California); Mohamad Towfik Krounbi (San Jose, California)
ASSIGNEE(S)	Grandis, Inc. (San Jose, California)
INVENTOR(S)	Dmytro Apalkov (San Jose, California); Mohamad Towfik Krounbi (San Jose, California)
ABSTRACT	A method and system for providing a magnetic junction usable in a magnetic device are described. The magnetic junction includes a pinned layer, a nonmagnetic spacer layer, and a free layer. The nonmagnetic spacer layer is between the pinned layer and the free layer. The free layer has an easy cone magnetic anisotropy. The magnetic junction is configured such that the free layer is switchable between a plurality of stable magnetic states when a write current is passed through the magnetic junction.
FILED	Friday, November 05, 2010
APPL NO	12/940926
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/421
VIEW PATENT	@ USPTO: Full Text PDF

08399964 — Multilayer structures for magnetic shielding

US 08399964	Katti
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Romney R. Katti (Shorewood, Minnesota)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	Romney R. Katti (Shorewood, Minnesota)
ABSTRACT	A magnetic shield is presented. The shield may be used to protect a microelectronic device from stray magnetic fields. The shield includes at least two layers. A first layer includes a magnetic material that may be used to block DC magnetic fields. A second layer includes a conductive material that may be used to block AC magnetic fields. Depending on the type of material that the first and second layers include, a third layer may be inserted in between the first and second layers. The third layer may include a non-conductive material that may be used to ensure that separate eddy current regions form in the first and second layers.
FILED	Monday, August 23, 2010
APPL NO	12/861442
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/659
VIEW PATENT	@ USPTO: Full Text PDF

08400172 — Degradation sensor

US 08400172	Wilson
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	Alan Richard Wilson (Glen Iris, Australia)
ASSIGNEE(S)	The Commonwealth of Australia, Department of Defense (, Australia)
INVENTOR(S)	Alan Richard Wilson (Glen Iris, Australia)
ABSTRACT	A sensor for monitoring a structure or material. The sensor has a continuous elongate conducting member embedded in an insulating material and a conductivity or resistance meter. The insulating material has one or more gaps that expose the conducting member without allowing direct contact between the insulating material and the structure or material when the sensor is placed against the structure or material. The meter is arranged to monitor conductivity or resistance between the conducting member and the structure or material being monitored, and/or between two regions of the conducting member.
FILED	Wednesday, January 28, 2009
APPL NO	12/863401
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/700
VIEW PATENT	@ USPTO: Full Text PDF

08400225 — Photocapacitively tunable electronic device utilizing electrical resonator with semiconductor junction

US 08400225	Sessions et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Walter D. Sessions (King George, Virginia); Kevin A. Boulais (Waldorf, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Walter D. Sessions (King George, Virginia); Kevin A. Boulais (Waldorf, Maryland)
ABSTRACT	An optically tunable cavity for an electronic device concurrently achieves high bandwidth (for example, at least about 10 percent, typically greater than about 50 percent) with high DC-RF efficiency (for example, at least about 50 percent, typically greater than about 85 percent). The electronic device may be a vacuum electronic device, including linear-beam and cross-field devices, with either an input circuit or an output circuit, or both, containing a photocapacitance-controlled resonator embedded such that a laser beam can impinge upon a semiconductor gap of the resonator. The laser beam may instantaneously change the resonant mode of the overall loaded cavity, thus allowing for amplification or oscillation of the desired frequency throughout the vacuum electronic device.
FILED	Wednesday, August 10, 2011
APPL NO	13/136904
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Oscillators 331/83
VIEW PATENT	@ USPTO: Full Text PDF

08400355 — Passive photonic dense wavelength-division multiplexing true-time-delay system

US 08400355	Gaeta
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	Celestino John Gaeta (Carlsbad, California)
ASSIGNEE(S)	Ipitek, Inc. (Carlsbad, California)
INVENTOR(S)	Celestino John Gaeta (Carlsbad, California)
ABSTRACT	A photonic true time delay system for steering one or more radio frequency beams from an electronically scanned array antenna incorporates passive optical true time delay modules for the entire array based upon dense-wavelength-division multiplexed encoding of optical time delays. In addition, electronic selection of time delays allows for elimination of optical filter tuning and optical switching, and can function in either or both transmit and receive modes of the antenna array.
FILED	Friday, April 03, 2009
APPL NO	12/418272
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Communications: Directive radio wave systems and devices 342/377
VIEW PATENT	@ USPTO: Full Text PDF

08400448 — Real-time lines-of-sight and viewsheds determination system

US 08400448	Doyle, Jr.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Robert J Doyle, Jr. (Alexandria, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert J Doyle, Jr. (Alexandria, Virginia)
ABSTRACT	A method for processing three-dimensional data that defines a three-dimensional scene, and determining and displaying lines-of-sight (LOS) and viewsheds on all visible surfaces of the scene, includes: i) assigning at a user-selected location at least one viewpoint in the scene; ii) applying ray tracing from locations in the scene to the viewpoint to determine locations in the scene that are in a line of sight (LOS) and outside the LOS of the viewpoint, thus determining the viewshed relative to the viewpoint while generating a set of color-coding information; iv) saving the set of color-coding information as a 2D texture image in graphics hardware memory; and v) compositing the 2D texture image over the 3D scene in a 3D window at a frame rate that enables real-time updating of the color coding as the scene is translated or rotated or the viewpoint is changed.
FILED	Monday, August 10, 2009
APPL NO	12/461350
ART UNIT	2678 — Selective Visual Display Systems
CURRENT CPC	Computer graphics processing and selective visual display systems 345/419
VIEW PATENT	@ USPTO: Full Text PDF

08400539 — High density composite focal plane array

US 08400539	Silva et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Raymond J. Silva (Saugus, Massachusetts); Dennis Bowler (Sudbury, Massachusetts); Gene Robillard (Stoneham, Massachusetts)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Raymond J. Silva (Saugus, Massachusetts); Dennis Bowler (Sudbury, Massachusetts); Gene Robillard (Stoneham, Massachusetts)
ABSTRACT	A composite focal plane assembly with an expandable architecture has a multi-layer, double-sided aluminum nitride (AlN) substrate and vertical architecture to achieve the dual function of focal plane and electronics backplane. Imaging dice and other electrical components are mounted and wire bonded to one surface and then direct backplane connectivity is provided on the opposing surface through a matrix of electrical contacts. In one embodiment, a flexible connector is sandwiched between the AlN focal plane and a FR-4 backplane is used to compensate for differences in coefficient of thermal expansion (CTE) between the AlN and commercially available high density circuit card connectors that are commonly manufactured from materials with CTE properties more closely approximating FR-4. In an alternate embodiment, the FR-4 and flexible connectors are eliminated by using high density circuit card connectors that are fabricated out of materials more closely matching the CTE of AlN.
FILED	Wednesday, December 03, 2008
APPL NO	12/327383
ART UNIT	2872 — Optics
CURRENT CPC	Television 348/294
VIEW PATENT	@ USPTO: Full Text PDF

08401117 — Method of adaptive modulation for cognitive radios using a fast and simplified modulation recognition

US 08401117	Su
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Wei Su (Bel Air, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Wei Su (Bel Air, Maryland)
ABSTRACT	Method for automatic modulation recognition in adaptive modulation based cognitive software defined radio (SDR), including receiving a transmitter signal from a transmitter; inputting signal data frame r(k), k=1, . . . , K; estimating SNR for data frame; feeding channel condition to transmitter; selecting one of plurality of predetermined modulation schemes from database; determining whether SNR(r(k))< or =threshold T⁽ⁱ⁾; reporting failure if SNR(r(k))< or =T⁽ⁱ⁾and if not then estimating mean b_j⁽ⁱ⁾(k) for r(k); calculating ∥r(k)−{circumflex over (b)}⁽ⁱ⁾(k)∥²; accumulating to calculate $g^{(i)} = \sum_{k = 1}^{K} { r (k) - {\hat{b}}^{(i)} (k) }^{2};$ repeating above steps from selecting for the other predetermined modulation schemes; finding minimum $g^{(i)} = \sum_{k = 1}^{K} { r (k) - {\hat{b}}^{(i)} (k) }^{2};$ determining whether [K/SNR(r(k))−g(I)]<predetermined D; reporting the modulation scheme if determination is yes and failure if no. An SDR can be configured to perform the above method.
FILED	Friday, November 04, 2011
APPL NO	13/373245
ART UNIT	2632 — Digital Communications
CURRENT CPC	Pulse or digital communications 375/316
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08401134 — Broadband high dynamic range digital receiving system for electromagnetic signals

US 08401134	Steinbrecher
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Donald H. Steinbrecher (Brookline, Massachusetts)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Donald H. Steinbrecher (Brookline, Massachusetts)
ABSTRACT	A method is provided for the design of a wide-band high dynamic-range electromagnetic signal receiving system. The method provides for receiving a plurality of analog signals, converting the plurality to a digital replica that can be processed to recover separate high-fidelity replicas of each individual signal in the received plurality. The method also provides increasing the signal dynamic range with a parallel architecture comprising “p” identical parallel analog-to-digital channels wherein the value of is determined by the ratio of the largest amplitude signal to the minimum detectable signal. Further, it is demonstrated that “p” is the fundamental limit on the number of parallel channels necessary to linearly process a specified plurality of signals containing a largest signal and a minimum detectable signal.
FILED	Thursday, July 08, 2010
APPL NO	12/832416
ART UNIT	2633 — Digital Communications
CURRENT CPC	Pulse or digital communications 375/347
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08401345 — Optical modulator with three-dimensional waveguide tapers

US 08401345	Zheng et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Xuezhe Zheng (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California); Dazeng Feng (El Monte, California); Mehdi Asghari (Pasadena, California)
ASSIGNEE(S)	Oracle America, Inc. (Redwood Shores, California)
INVENTOR(S)	Xuezhe Zheng (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California); Dazeng Feng (El Monte, California); Mehdi Asghari (Pasadena, California)
ABSTRACT	An integrated circuit that includes an optical waveguide defined in a semiconductor layer is described. In this integrated circuit, light is coupled between the optical waveguide and an optical modulator, which is disposed on the optical waveguide, using 3-dimensional (3-D) taper structures that are proximate to the ends of the optical modulator. The cross-sectional areas of these 3-D taper structures transition, over a distance, from that of the optical waveguide (distal from the optical modulator) to that of optical modulator (proximate to the ends of the optical modulator). In this way, a spatial extent of an optical mode in the optical waveguide and a spatial extent of the optical mode in the optical modulator may be approximately matched to reduce the optical loss when the light is coupled to or from the optical modulator.
FILED	Wednesday, June 16, 2010
APPL NO	12/816935
ART UNIT	2874 — Optics
CURRENT CPC	Optical waveguides 385/2
VIEW PATENT	@ USPTO: Full Text PDF

08401398 — Modulator for frequency-shift keying of optical signals

US 08401398	Robinson et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Office of Scientific Research (AFOSR) Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E) MIT Lincoln Laboratory (MITLL) Federally Funded Research and Development Center (FFRDC) Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S)	Bryan S. Robinson (Arlington, Massachusetts); Don M. Boroson (Needham, Massachusetts); Scott A. Hamilton (Lexington, Massachusetts); Shelby J. Savage (Lexington, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Bryan S. Robinson (Arlington, Massachusetts); Don M. Boroson (Needham, Massachusetts); Scott A. Hamilton (Lexington, Massachusetts); Shelby J. Savage (Lexington, Massachusetts)
ABSTRACT	Described are an FSK modulator and a method for large-alphabet FSK modulation. The FSK modulator and the method are based on filtering of a multi-tone optical source such as a mode-locked laser which provides a comb distribution of tones. A frequency-selective component selects for transmission a subset of the tones. In various embodiments the frequency-selective component is a Mach-Zehnder interferometer filter or a microring resonator filter. A second frequency-selective component selects a subset of the tones from the comb distribution provided by the first frequency-selective component. Still more frequency-selective components can be used according to the number of tones supplied by the multi-tone optical source to the FSK modulator. The optical signal exiting the last frequency-selective component includes only a single tone which corresponds to the symbol to be transmitted.
FILED	Thursday, March 06, 2008
APPL NO	12/530660
ART UNIT	2634 — Digital Communications
CURRENT CPC	Optical communications 398/187
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08401509 — Two stage radio frequency interference cancellation system and method

US 08401509	Gupta et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Deepnarayan Gupta (Hawthorne, New York); Amol Inamdar (Elmsford, New York)
ASSIGNEE(S)	Hypres, Inc. (Elmsford, New York)
INVENTOR(S)	Deepnarayan Gupta (Hawthorne, New York); Amol Inamdar (Elmsford, New York)
ABSTRACT	A radio frequency receiver subject to a large in-band interferor employs active cancellation with coarse and at least one cancellation signals, each with a respective radio frequency combiner, in order to increase the effective dynamic range of the receiver for weak signals of interest. One or both can be digitally synthesized. This is particularly applicable for co-site interference, whereby the interfering transmit signal is directly accessible. A similar system and method may also be applied to external interferors such as those produced by deliberate or unintentional jamming signals, or by strong multipath signals. An adaptive algorithm may be used for dynamic delay and gain matching. In a preferred embodiment, a hybrid technology hybrid temperature system incorporates both superconducting and semiconducting components to achieve enhanced broadband performance.
FILED	Friday, August 17, 2012
APPL NO	13/588582
ART UNIT	2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Telecommunications 455/296
VIEW PATENT	@ USPTO: Full Text PDF

08401600 — Superconducting multi-bit digital mixer

US 08401600	Filippov et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Timur V. Filippov (Mahopac, New York); Alexander F. Kirichenko (Pleasantville, New York); Deepnarayan Gupta (Hawthorne, New York)
ASSIGNEE(S)	Hypres, Inc. (Elmsford, New York)
INVENTOR(S)	Timur V. Filippov (Mahopac, New York); Alexander F. Kirichenko (Pleasantville, New York); Deepnarayan Gupta (Hawthorne, New York)
ABSTRACT	A superconducting multi-bit digital mixer, designed using rapid single flux quantum (RSFQ) logic, for multiplying two independent digital streams, at least one of these comprising a plurality of parallel bit lines, wherein the output is also a similar plurality of bit lines. In a preferred embodiment, one of the digital streams represents a local oscillator signal, and the other digital stream digital radio frequency input from an analog-to-digital converter. The multi-bit mixer comprises an array of bit-slices, with the local oscillator signal generated using shift registers. This multi-bit mixer is suitable for an integrated circuit with application to a broadband digital radio frequency receiver, a digital correlation receiver, or a digital radio frequency transmitter. A synchronous pulse distribution network is used to ensure proper operation at data rates of 20 GHz or above.
FILED	Tuesday, August 02, 2011
APPL NO	13/196494
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Superconductor technology: Apparatus, material, process 55/190
VIEW PATENT	@ USPTO: Full Text PDF

08401989 — Validation mechanisms for simulations of complex systems

US 08401989	Reynolds
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	William N. Reynolds (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	William N. Reynolds (Albuquerque, New Mexico)
ABSTRACT	A method of and apparatus and software for validating a computer model of a complex system comprising eliciting information regarding the complex system from one or more human experts, determining from the elicited information a set of variables and a set of constraints on those variables regarding the complex system, automatically by computer examining output of the computer model to locate violations of determined constraints, and generating output establishing any located violations.
FILED	Friday, February 12, 2010
APPL NO	12/705084
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Artificial intelligence 76/62
VIEW PATENT	@ USPTO: Full Text PDF

Department of Health and Human Services (HHS)

08398541 — Interactive user interfaces for robotic minimally invasive surgical systems

US 08398541	DiMaio et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Simon P. DiMaio (Sunnyvale, California); Christopher J. Hasser (Los Altos, California); Russell H. Taylor (Severna Park, Maryland); David Q. Larkin (Menlo Park, California); Peter Kazanzides (Towson, Maryland); Anton Deguet (Baltimore, Maryland); Bálazs Peter Vágvölgyi (Baltimore, Maryland); Joshua Leven (Astoria, New York)
ASSIGNEE(S)	Intuitive Surgical Operations, Inc. (Sunnyvale, California); Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Simon P. DiMaio (Sunnyvale, California); Christopher J. Hasser (Los Altos, California); Russell H. Taylor (Severna Park, Maryland); David Q. Larkin (Menlo Park, California); Peter Kazanzides (Towson, Maryland); Anton Deguet (Baltimore, Maryland); Bálazs Peter Vágvölgyi (Baltimore, Maryland); Joshua Leven (Astoria, New York)
ABSTRACT	In one embodiment of the invention, a method for a minimally invasive surgical system is disclosed. The method includes capturing and displaying camera images of a surgical site on at least one display device at a surgeon console; switching out of a following mode and into a masters-as-mice (MaM) mode; overlaying a graphical user interface (GUI) including an interactive graphical object onto the camera images; and rendering a pointer within the camera images for user interactive control. In the following mode, the input devices of the surgeon console may couple motion into surgical instruments. In the MaM mode, the input devices interact with the GUI and interactive graphical objects. The pointer is manipulated in three dimensions by input devices having at least three degrees of freedom. Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices.
FILED	Monday, August 11, 2008
APPL NO	12/189615
ART UNIT	3779 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Surgery 6/111
VIEW PATENT	@ USPTO: Full Text PDF

08398549 — Ultrasound methods, systems and computer program products for imaging contrasting objects using combined images

US 08398549	Palmeri et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Mark L. Palmeri (Durham, North Carolina); Veronica Rotemberg (Durham, North Carolina); Stephen J. Rosenzweig (Durham, North Carolina); Kathryn R. Nightingale (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Mark L. Palmeri (Durham, North Carolina); Veronica Rotemberg (Durham, North Carolina); Stephen J. Rosenzweig (Durham, North Carolina); Kathryn R. Nightingale (Durham, North Carolina)
ABSTRACT	A system for identifying a presence of an object in a tissue region of interest includes a controller configured to obtain first and second image data sets from the region of interest. A contrast identification module is configured to identify a contrasting region of altered stiffness in the first image data set corresponding to an object in the tissue region of interest. An image data enhancement module is configured to identify the object in the second image data set based on the contrasting region of altered stiffness in the first image data set.
FILED	Tuesday, February 16, 2010
APPL NO	12/706269
ART UNIT	3777 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Surgery 6/437
VIEW PATENT	@ USPTO: Full Text PDF

08398550 — Techniques to evaluate mechanical properties of a biologic material

US 08398550	Insana et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Michael F. Insana (Urbana, Illinois); Marko Orescanin (Urbana, Illinois); Kathleen Toohey (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Michael F. Insana (Urbana, Illinois); Marko Orescanin (Urbana, Illinois); Kathleen Toohey (Urbana, Illinois)
ABSTRACT	A system includes an acoustic radiation force source that is structured to generate an acoustic radiation force at one or more frequencies. A shear wave transmission device is embedded in a mass including a biologic material. The shear wave transmission device is responsive to the acoustic radiation force source to transmit shear waves through the biologic material. A Doppler ultrasonic device detects the shear waves and generates data representative of the shear waves. A processing device determines one or more mechanical properties of the biologic material from the data.
FILED	Tuesday, December 01, 2009
APPL NO	12/592717
ART UNIT	3737 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Surgery 6/438
VIEW PATENT	@ USPTO: Full Text PDF

08398576 — Removal of contrast agents from blood

US 08398576	Angheloiu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	George Oliviu Angheloiu (Dubois, Pennsylvania); John A. Kellum, Jr. (Pittsburgh, Pennsylvania); William D. Anderson (Pittsburgh, Pennsylvania); Catalin Toma (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	George Oliviu Angheloiu (Dubois, Pennsylvania); John A. Kellum, Jr. (Pittsburgh, Pennsylvania); William D. Anderson (Pittsburgh, Pennsylvania); Catalin Toma (Pittsburgh, Pennsylvania)
ABSTRACT	The invention provides a system and a method for removal of contrast from blood. In one aspect, the invention provides a catheter for removal of contrast from the veins that drain the cerebral circulation. In a second aspect, the invention provides a method for removing contrast from blood by contacting the blood with a sorbent.
FILED	Wednesday, April 02, 2008
APPL NO	12/061562
ART UNIT	3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery 64/6.90
VIEW PATENT	@ USPTO: Full Text PDF

08398971 — Methods, compounds, and compositions for treatment and prophylaxis in the respiratory tract

US 08398971	Fang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Fang Fang (Rancho Santa Fe, California); David Wurtman (San Diego, California); Ron Moss (Encinitas, California); Michael P. Malakhov (San Francisco, California)
ASSIGNEE(S)	NexBio, Inc. (San Diego, California)
INVENTOR(S)	Fang Fang (Rancho Santa Fe, California); David Wurtman (San Diego, California); Ron Moss (Encinitas, California); Michael P. Malakhov (San Francisco, California)
ABSTRACT	The present invention provides a method of reducing the quanitity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition.
FILED	Friday, November 05, 2010
APPL NO	12/940742
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/94.650
VIEW PATENT	@ USPTO: Full Text PDF

08398973 — Methods and compositions for preventing adhesion

US 08398973	Cruikshank et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	William W. Cruikshank (Westford, Massachusetts); David M. Center (Wellesley Hills, Massachusetts)
ASSIGNEE(S)	Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	William W. Cruikshank (Westford, Massachusetts); David M. Center (Wellesley Hills, Massachusetts)
ABSTRACT	This invention provides methods and compositions for preventing post-surgical adhesion formation based on use of an interleukin-16 (IL-16) antagonist, including an IL-16 antagonist peptide and/or an IL-16 antagonist antibody.
FILED	Thursday, April 16, 2009
APPL NO	12/988145
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/130.100
VIEW PATENT	@ USPTO: Full Text PDF

08398989 — Human cystathionine β-synthase variants and methods of production thereof

US 08398989	Kraus et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Jan P. Kraus (Littleton, Colorado); Jana Oliveriusova (Morrison, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S)	Jan P. Kraus (Littleton, Colorado); Jana Oliveriusova (Morrison, Colorado)
ABSTRACT	Human cystathionine β-synthase variants are disclosed, as well as a method to produce recombinant human cystathionine β-synthase and variants thereof. More particularly, the role of both the N-terminal and C-terminal regions of human CBS has been studied, and a variety of truncation mutants and modified CBS homologues are described. In addition, a method to express and purify recombinant human cystathionine β-synthase (CBS) and variants thereof which have only one or two additional amino acid residues at the N-terminus are described.
FILED	Tuesday, August 30, 2011
APPL NO	13/221379
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/192.100
VIEW PATENT	@ USPTO: Full Text PDF

08399000 — Haemophilus influenzae type IV pili

US 08399000	Bakaletz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	Lauren O. Bakaletz (Hilliard, Ohio); Robert S. Munson, Jr. (Hilliard, Ohio)
ASSIGNEE(S)	Nationwide Children's Hospital, Inc. (Columbus, Ohio)
INVENTOR(S)	Lauren O. Bakaletz (Hilliard, Ohio); Robert S. Munson, Jr. (Hilliard, Ohio)
ABSTRACT	The invention described herein relates to a Haemophilus influenzae (H. influenzae) regulon encoding type IV pili. In particular, the invention relates to type pili from nontypeable H. influenzae (NTHi) and from H. influenzae strains a, b, c, e and f. The invention provides isolated H. influenzae pilus polynucleotides and polypeptides encoded by the polynucleotides as well as polynucleotides and polypeptides encoded by the polynucleotides involved in the assembly/disassembly of the structure. The invention also relates to uses of these polynucleotides and/or polypeptides including methods for eliciting an immune response to H. influenzae and methods of treating and preventing H. influenzae related pathological conditions.
FILED	Wednesday, January 12, 2011
APPL NO	13/005166
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/256.100
VIEW PATENT	@ USPTO: Full Text PDF

08399005 — Use of nitric oxide to enhance the efficacy of silver and other topical wound care agents

US 08399005	Schoenfisch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Mark H. Schoenfisch (Chapel Hill, North Carolina); Evan M. Hetrick (Indianapolis, Indiana); Nathan A. Stasko (Durham, North Carolina); C. Bryce Johnson (John's Island, South Carolina)
ASSIGNEE(S)	University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Mark H. Schoenfisch (Chapel Hill, North Carolina); Evan M. Hetrick (Indianapolis, Indiana); Nathan A. Stasko (Durham, North Carolina); C. Bryce Johnson (John's Island, South Carolina)
ABSTRACT	The present invention is directed to compositions comprising at least one nitric oxide donor and at least one second therapeutically active agent with antimicrobial or wound healing capability. In one embodiment, the nitric oxide donor is a nanoparticle which is designed to control for the amount and duration of release of nitric oxide. The nanoparticle may further comprise the additional therapeutically active agent. The composition is useful for enhancing wound healing and for treating and preventing microbial infection. In one embodiment, the composition is directed toward reducing oral bacteria or dental plaque. The combination of one or more nitric oxide donors and one or more additional therapeutically active agent results in unexpected synergistic effects, wherein both the antimicrobial efficacy of the nitric oxide and the antimicrobial or wound healing efficacy of the second therapeutically active agent are enhanced. As a result, a patient may benefit from reduced dosage requirements and a reduced likelihood of antimicrobial resistance. The composition may be formulated for local or systemic administration, for topical applications as well as for use in coatings for medical supplies and devices.
FILED	Friday, October 10, 2008
APPL NO	12/682305
ART UNIT	1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/417
VIEW PATENT	@ USPTO: Full Text PDF

08399185 — Regulators of NFAT

US 08399185	Rao et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Anjana Rao (Cambridge, Massachusetts); Stefan Feske (New York, New York); Patrick Hogan (Cambridge, Massachusetts); Yousang Gwack (Los Angeles, California)
ASSIGNEE(S)	Immune Disease Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Anjana Rao (Cambridge, Massachusetts); Stefan Feske (New York, New York); Patrick Hogan (Cambridge, Massachusetts); Yousang Gwack (Los Angeles, California)
ABSTRACT	Disclosed are methods of identifying an agent that modulates an NFAT regulator protein. One such method comprises contacting at least one test agent with a recombinant cell comprising at least one NFAT regulator protein or fragment or derivative thereof, assessing the effect of the test agent on an activity, interaction, expression, or binding to the NFAT regulator protein or fragment or derivative thereof, and identifying the test agent that has an effect on an activity, interaction, expression, or binding to the NFAT regulator protein or fragment or derivative thereof, whereby the identified test agent is characterized as an agent that modulates an NFAT regulator protein. Methods of identifying an agent that modulates intracellular calcium, methods to screen for an agent that modulates NFAT regulator function, methods to diagnose unexplained immunodeficiency in a subject, and methods for identifying an agent for treating or preventing a disease or disorder associated with a NFAT regulator protein or calcium signaling are also disclosed.
FILED	Friday, January 05, 2007
APPL NO	12/160030
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

08399193 — DNA methylation biomarkers for lung cancer

US 08399193	Pfeifer et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Gerd P. Pfeifer (Duarte, California); Tibor A. Rauch (Chicago, Illinois); Zunde Wang (San Gabriel, California); Xiwei Wu (Duarte, California)
ASSIGNEE(S)	City of Hope (Duarte, California)
INVENTOR(S)	Gerd P. Pfeifer (Duarte, California); Tibor A. Rauch (Chicago, Illinois); Zunde Wang (San Gabriel, California); Xiwei Wu (Duarte, California)
ABSTRACT	The present invention relates to the identification of novel DNA biomarkers and the use of the aberrant methylation patterns of the biomarkers to diagnose a disease or a condition (e.g., a cancer) associated therewith. In particular, the present invention relates to the use of the novel DNA biomarkers to diagnose lung cancers, e.g., squamous cell carcinomas and adenocarcinomas.
FILED	Friday, August 29, 2008
APPL NO	12/231337
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.110
VIEW PATENT	@ USPTO: Full Text PDF

08399207 — Monoclonal antibodies against osteopontin

US 08399207	Liaw et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Lucy Liaw (South Portland, Maine); Ah-Kau Ng (Portland, Maine)
ASSIGNEE(S)	Maine Medical Center (Portland, Maine)
INVENTOR(S)	Lucy Liaw (South Portland, Maine); Ah-Kau Ng (Portland, Maine)
ABSTRACT	The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein. The present invention also relates to assays for the determination of the presence of osteopontin fragments in samples obtained from subjects and, further, the correlation of osteopontin fragment levels fragment levels with disease detection, progression and prognosis.
FILED	Monday, January 03, 2011
APPL NO	12/983650
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.230
VIEW PATENT	@ USPTO: Full Text PDF

08399213 — Method for monitoring intracellular tyrosine phosphatase activity

US 08399213	Bottini et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Nunzio Bottini (San Diego, California); Stephanie Stanford (San Diego, California); Amy Barrios (Salt Lake City, Utah); Sayantan Mitra (San Diego, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Nunzio Bottini (San Diego, California); Stephanie Stanford (San Diego, California); Amy Barrios (Salt Lake City, Utah); Sayantan Mitra (San Diego, California)
ABSTRACT	The invention relates in general to tyrosine dephosphorylation. More specifically, the invention relates to methods and compositions for monitoring intracellular tyrosine dephosphorylation at the single cell level. The invention further relates to techniques that can be used as aid in the development of novel therapeutics, and monitor regulation of intracellular tyrosine phosphatase activity at the single cell level.
FILED	Wednesday, September 30, 2009
APPL NO	12/571301
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/21
VIEW PATENT	@ USPTO: Full Text PDF

08399233 — Histone deacetylases, and uses related thereto

US 08399233	Schreiber et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Stuart L. Schreiber (Boston, Massachusetts); Jack Taunton (Somerville, Massachusetts); Christian A. Hassig (Berkeley, California); Timothy F. Jamison (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Stuart L. Schreiber (Boston, Massachusetts); Jack Taunton (Somerville, Massachusetts); Christian A. Hassig (Berkeley, California); Timothy F. Jamison (Cambridge, Massachusetts)
ABSTRACT	The present invention concerns the discovery that proteins encoded by a family of genes, termed here HDx-related genes, which are involved in the control of chromatin structure and, thus in transcription and translation. The present invention makes available compositions and methods that can be utilized, for example to control cell proliferation and differentiation in vitro and in vivo.
FILED	Monday, August 16, 2004
APPL NO	10/919217
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/194
VIEW PATENT	@ USPTO: Full Text PDF

08399241 — Modulators of alpha-synuclein toxicity

US 08399241	Lindquist et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Susan L. Lindquist (Chestnut Hill, Massachusetts); Aaron D. Gitler (Philadelphia, Pennsylvania); Anil Cashikar (Martinez, Georgia); Antony A. Cooper (Sydney, Australia); Cole M. Haynes (New York, New York)
ASSIGNEE(S)	Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S)	Susan L. Lindquist (Chestnut Hill, Massachusetts); Aaron D. Gitler (Philadelphia, Pennsylvania); Anil Cashikar (Martinez, Georgia); Antony A. Cooper (Sydney, Australia); Cole M. Haynes (New York, New York)
ABSTRACT	Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity.
FILED	Thursday, December 01, 2005
APPL NO	11/720586
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/254.200
VIEW PATENT	@ USPTO: Full Text PDF

08399258 — Biological markers for longevity and diseases and uses thereof

US 08399258	Barzilai
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Nir Barzilai (Hartsdale, New York)
ASSIGNEE(S)	Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S)	Nir Barzilai (Hartsdale, New York)
ABSTRACT	This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the −641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
FILED	Friday, December 05, 2008
APPL NO	12/315845
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Analytical and immunological testing 436/71
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08399339 — Nanosensors

US 08399339	Lieber et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF)
APPLICANT(S)	Charles M. Lieber (Lexington, Massachusetts); Hongkun Park (Lexington, Massachusetts); Qingqiao Wei (Corvallis, Oregon); Yi Cui (Sunnyvale, California); Wenjie Liang (Oakland, California)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Charles M. Lieber (Lexington, Massachusetts); Hongkun Park (Lexington, Massachusetts); Qingqiao Wei (Corvallis, Oregon); Yi Cui (Sunnyvale, California); Wenjie Liang (Oakland, California)
ABSTRACT	Electrical devices comprised of nanowires are described, along with methods of their manufacture and use. The nanowires can be nanotubes and nanowires. The surface of the nanowires may be selectively functionalized Nanodetector devices are described.
FILED	Monday, April 11, 2011
APPL NO	13/083817
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/478
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08399383 — Protein chips for high throughput screening of protein activity

US 08399383	Snyder et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Michael Snyder (Fairfield, Connecticut); Mark Reed (Monroe, Connecticut); Heng Zhu (New Haven, Connecticut); James Frank Klemic (New Haven, Connecticut)
ASSIGNEE(S)	Yale University (New Haven, Connecticut)
INVENTOR(S)	Michael Snyder (Fairfield, Connecticut); Mark Reed (Monroe, Connecticut); Heng Zhu (New Haven, Connecticut); James Frank Klemic (New Haven, Connecticut)
ABSTRACT	The present invention relates to protein chips useful for the large-scale study of protein function where the chip contains densely packed reaction wells. The invention also relates to methods of using protein chips to assay simultaneously the presence, amount, and/or function of proteins present in a protein sample or on one protein chip, or to assay the presence, relative specificity, and binding affinity of each probe in a mixture of probes for each of the proteins on the chip. The invention also relates to methods of using the protein chips for high density and small volume chemical reactions. Also, the invention relates to polymers useful as protein chip substrates and methods of making protein chips. The invention further relates to compounds useful for the derivatization of protein chip substrates.
FILED	Friday, May 04, 2001
APPL NO	09/849781
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Combinatorial chemistry technology: Method, library, apparatus 56/14
VIEW PATENT	@ USPTO: Full Text PDF

08399407 — Non-standard insulin analogues

US 08399407	Weiss
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Michael A. Weiss (Moreland Hills, Ohio)
ASSIGNEE(S)	Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S)	Michael A. Weiss (Moreland Hills, Ohio)
ABSTRACT	An insulin analogue comprises a B-chain polypeptide containing at least one alteration selected from a methylated phenylalanine substitution at position B24 and an addition of two amino acids to the carboxyl end of the B-chain polypeptide. A first amino acid at position B31 is selected from glutamate and aspartate, and a second amino acid at position B32 is selected from glutamate, alanine and aspartate. The methylated phenylalanine may be ortho-monofluoro-phenylalanine, meta-monobromo-phenylalanine or para-monochloro-phenylalanine. The analogue may be an analogue of a mammalian insulin, such as human insulin. A nucleic acid encoding such an insulin analogue is also provided. A method of treating a patient comprises administering a physiologically effective amount of the insulin analogue or a physiologically acceptable salt thereof to a patient.
FILED	Friday, September 17, 2010
APPL NO	12/884943
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/5.900
VIEW PATENT	@ USPTO: Full Text PDF

08399419 — Antibacterial aminoglycoside analogs

US 08399419	Aggen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	James Bradley Aggen (Burlingame, California); Martin Sheringham Linsell (San Mateo, California); Adam Aaron Goldblum (Berkeley, California); Darin James Hildebrandt (Mountain View, California); Timothy Robert Kane (Moss Beach, California); Paola Dozzo (San Francisco, California); Micah James Gliedt (Sunnyvale, California); Stephen Hanessian (Beaconsfield, Canada); Alexandre Giguère (Montreal, Canada); Justyna Grzyb (Montreal, Canada); Juan Pablo Maianti (Montreal, Canada)
ASSIGNEE(S)	Achaogen, Inc. (South San Francisco, California)
INVENTOR(S)	James Bradley Aggen (Burlingame, California); Martin Sheringham Linsell (San Mateo, California); Adam Aaron Goldblum (Berkeley, California); Darin James Hildebrandt (Mountain View, California); Timothy Robert Kane (Moss Beach, California); Paola Dozzo (San Francisco, California); Micah James Gliedt (Sunnyvale, California); Stephen Hanessian (Beaconsfield, Canada); Alexandre Giguère (Montreal, Canada); Justyna Grzyb (Montreal, Canada); Juan Pablo Maianti (Montreal, Canada)
ABSTRACT	Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q₁, Q₂, Z₁, Z₂, Z₃, Z₄, R₁, R₂and R₃are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
FILED	Wednesday, March 09, 2011
APPL NO	13/044234
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/38
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08399421 — Treatment for neuropathic pain due to spinal cord injury

US 08399421	Perez-Polo
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	J. Regino Perez-Polo (Galveston, Texas)
ASSIGNEE(S)	The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	J. Regino Perez-Polo (Galveston, Texas)
ABSTRACT	The present invention is drawn to treatment of neuropathic pain due to spinal cord injury. In this regard, the present invention discloses methods and composition to treat neuropathic pain.
FILED	Monday, March 31, 2008
APPL NO	12/079956
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44.A00
VIEW PATENT	@ USPTO: Full Text PDF

08399425 — Alleviating neuropathic pain with EETs and sEH inhibitors

US 08399425	Hammock et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	Bruce D. Hammock (Davis, California); Ahmet Bora Inceoglu (Davis, California); Steven L. Jinks (Davis, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Bruce D. Hammock (Davis, California); Ahmet Bora Inceoglu (Davis, California); Steven L. Jinks (Davis, California)
ABSTRACT	The invention discloses methods of using cis-epoxyeicosantrienoic acids (“EETs”), inhibitors of soluble epoxide hydrolase (“sEH”), or a combination of an EET and an inhibitor of sEH, to alleviate neuropathic pain in subjects suffering from such pain.
FILED	Friday, November 07, 2008
APPL NO	12/741016
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44
VIEW PATENT	@ USPTO: Full Text PDF

08399428 — Nucleosides with antiviral and anticancer activity

US 08399428	Wagner
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Carston R. Wagner (St. Paul, Minnesota)
ASSIGNEE(S)	Regents of the University of Minnesota (St. Paul, Minnesota)
INVENTOR(S)	Carston R. Wagner (St. Paul, Minnesota)
ABSTRACT	The invention provides a compound of formula (I), wherein R₁-R₆and X have any of the values described, as well as pharmaceutical compositions comprising such compounds and therapeutic methods comprising the administration of such compounds.
FILED	Thursday, December 08, 2005
APPL NO	11/721325
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/48
VIEW PATENT	@ USPTO: Full Text PDF

08399434 — Method of activation of oxazaphosphorines

US 08399434	Spasojevic et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) U.S. Public Health Service (USPHS)
APPLICANT(S)	Ivan Spasojevic (Durham, North Carolina); Michael O. Colvin (Chapel Hill, North Carolina); Ines Batinic-Haberle (Durham, North Carolina); Susan M. Ludeman (Delmar, New York); Michael P. Gamcsik (Chapel Hill, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Ivan Spasojevic (Durham, North Carolina); Michael O. Colvin (Chapel Hill, North Carolina); Ines Batinic-Haberle (Durham, North Carolina); Susan M. Ludeman (Delmar, New York); Michael P. Gamcsik (Chapel Hill, North Carolina)
ABSTRACT	The present invention provides a method of hydroxylating or oxidizing a compound of interest in a subject (e.g., a cytotoxic oxazaphosphorine prodrug), by administering the compound of interest to the subject; and concurrently administering the subject a metalloporphyrin in an amount effective to hydroxylate or oxidize the compound of interest in the subject.
FILED	Tuesday, November 06, 2007
APPL NO	12/375482
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/90
VIEW PATENT	@ USPTO: Full Text PDF

08399441 — Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis

US 08399441	Ren et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Shunlin Ren (Richmond, Virginia); William M. Pandak (Richmond, Virginia)
ASSIGNEE(S)	Virginia Commonwealth University (Richmond, Virginia)
INVENTOR(S)	Shunlin Ren (Richmond, Virginia); William M. Pandak (Richmond, Virginia)
ABSTRACT	The sulfated oxysterol 5-cholesten-3β, 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided.
FILED	Friday, February 19, 2010
APPL NO	12/708803
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/182
VIEW PATENT	@ USPTO: Full Text PDF

08399510 — Method of activating NK cells

US 08399510	Wahle et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Joseph Wahle (St. Louis, Missouri); William Garrow Kerr (Syracuse, New York)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Joseph Wahle (St. Louis, Missouri); William Garrow Kerr (Syracuse, New York)
ABSTRACT	The present invention provides a method of mediating hypo-activation of NK cells. Methods of the present invention comprise administering to a subject an effective amount of broad acting phosphotase inhibitor, such as sodium orthovanadate, SHP specific inhibitor. In one embodiment, the SHP specific inhibitor is NSC119910.
FILED	Monday, October 12, 2009
APPL NO	12/577436
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/454
VIEW PATENT	@ USPTO: Full Text PDF

08399628 — Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same and methods of use thereof

US 08399628	Choi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Yongwon Choi (New York, New York); Brian Wong (New York, New York); Regis Josien (New York, New York); Ralph Steinman (Westport, Connecticut)
ASSIGNEE(S)	The Rockefeller University (New York, New York)
INVENTOR(S)	Yongwon Choi (New York, New York); Brian Wong (New York, New York); Regis Josien (New York, New York); Ralph Steinman (Westport, Connecticut)
ABSTRACT	A method of modulating immune response in an animal is disclosed. Such a method interacting the immature dendritic cells from the animal with an antigen ex vivo so that the immature dendritic cells present the antigen on their surfaces, inducing maturation of the immature dendritic cells ex vivo, and contacting the mature dendritic cells ex vivo with a modulator comprising TRANCE, conservative variants thereof, fragments thereof, analogs or derivatives thereof, or a fusion protein comprising the amino acid sequence of TRANCE, conservative variants thereof, or fragments thereof. After contacting the modulator ex vivo, the mature dendritic cells are introduced into the animal. As a result, immune response in the animal towards the antigen is modulated relative to the immune response against the antigen in an animal in which dendritic cells did not interact with the antigen ex vivo, and did not contact a modulator ex vivo. Preferably, the method of the present invention results in increasing immune response towards the antigen in the animal.
FILED	Wednesday, July 21, 2010
APPL NO	12/840967
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.100
VIEW PATENT	@ USPTO: Full Text PDF

08399644 — High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same

US 08399644	Zhan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	Chang-Guo Zhan (Lexington, Kentucky); Hoon Cho (Lexington, Kentucky); Hsin-Hsiung Tai (Lexington, Kentucky)
ASSIGNEE(S)	University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S)	Chang-Guo Zhan (Lexington, Kentucky); Hoon Cho (Lexington, Kentucky); Hsin-Hsiung Tai (Lexington, Kentucky)
ABSTRACT	A novel computational method and generation of mutant butyrylcholinesterase for cocaine hydrolysis is provided. The method includes molecular modeling a possible BChE mutant and conducting molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations thereby providing a screening method of possible BChE mutants by predicting which mutant will lead to a more stable transition state for a rate determining step. Site-directed mutagenesis, protein expression, and protein activity is conducted for mutants determined computationally as being good candidates for possible BChE mutants, i.e., ones predicted to have higher catalytic efficiency as compared with wild-type BChE. In addition, mutants A199S/A328W/Y332G, A199S/F227A/A328W/Y332G, A199S/S287G/A328W/Y332G, A199S/F227A/S287G/A328W/Y332G, and A199S/F227A/S287G/A328W/E441D all have enhanced catalytic efficiency for (−)-cocaine compared with wild-type BChE.
FILED	Tuesday, April 17, 2012
APPL NO	13/449107
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Organic compounds 536/23.200
VIEW PATENT	@ USPTO: Full Text PDF

08399645 — Chimeric receptors with 4-1BB stimulatory signaling domain

US 08399645	Campana et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Dario Campana (Germantown, Tennessee); Chihaya Imai (Niigata, Japan)
ASSIGNEE(S)	St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee)
INVENTOR(S)	Dario Campana (Germantown, Tennessee); Chihaya Imai (Niigata, Japan)
ABSTRACT	The present invention relates to a chimeric receptor capable of signaling both a primary and a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway without binding to the natural ligand. The cytoplasmic domain of the receptor contains a portion of the 4-1BB signaling domain. Embodiments of the invention relate to polynucleotides that encode the receptor, vectors and host cells encoding a chimeric receptor, particularly including T cells and natural killer (NK) cells and methods of use.
FILED	Thursday, July 12, 2012
APPL NO	13/548148
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Organic compounds 536/23.400
VIEW PATENT	@ USPTO: Full Text PDF

08399684 — Sulfonamide-based organocatalysts and method for their use

US 08399684	Carter et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) U.S. State Government State of Oregon
APPLICANT(S)	Rich Garrett Carter (Corvallis, Oregon); Hua Yang (Corvallis, Oregon)
ASSIGNEE(S)	State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Rich Garrett Carter (Corvallis, Oregon); Hua Yang (Corvallis, Oregon)
ABSTRACT	Organocatalysts, particularly proline sulfonamide organocatalysts, having a first general formula as follows are disclosed. Embodiments of a method for using these organocatalysts also are disclosed. The method comprises providing a disclosed organocatalyst, and performing a reaction, often an enantioselective or diastereoselective reaction, using the organocatalyst. Solely by way of example, disclosed catalysts can be used to perform aldol reactions, conjugate additions, Michael additions, Robinson annulations, Mannich reactions, α-aminooxylations, α-hydroxyaminations, α-aminations and alkylation reactions. Certain of such reactions are intramolecular cyclizations used to form cyclic compounds, such as 5-or 6-membered rings, having one or more chiral centers Disclosed organocatalysts generally are much more soluble in typical solvents used for organic synthesis than are known compounds. Moreover, the reaction yield is generally quite good with disclosed compounds, as is their enantioselective and diastereoselective effectiveness.
FILED	Wednesday, March 17, 2010
APPL NO	12/726212
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Organic compounds 548/495
VIEW PATENT	@ USPTO: Full Text PDF

08399689 — Chrysophaentin antimicrobial compounds that inhibit FtsZ protein

US 08399689	Bewley et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Carole A. Bewley (Bethesda, Maryland); Alberto Plaza (Arlington, Virginia); Jessica Keffer (Rockville, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Carole A. Bewley (Bethesda, Maryland); Alberto Plaza (Arlington, Virginia); Jessica Keffer (Rockville, Maryland)
ABSTRACT	Embodiments of antimicrobial chrysophaentin compounds, pharmaceutical compositions including the chrysophaentin compounds, and methods for using the chrysophaentin compounds are disclosed. Some embodiments of the disclosed compounds are isolated from Chrysophaeum taylori. Certain embodiments of the chrysophaentin compounds inhibit FtsZ protein, thereby inhibiting the growth of clinically relevant bacteria, including drug-resistant strains.
FILED	Friday, February 25, 2011
APPL NO	13/578803
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Organic compounds 549/348
VIEW PATENT	@ USPTO: Full Text PDF

08400152 — Method for k-space reconstruction in magnetic resonance inverse imaging

US 08400152	Lin
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Fa-Hsuan Lin (Brookline, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Fa-Hsuan Lin (Brookline, Massachusetts)
ABSTRACT	A method for parallel magnetic resonance imaging (“pMRI”) that does not require the explicit estimation of a coil sensitivity map is provided. Individual coil images are reconstructed from undersampled scan data that is acquired with a radio frequency (RF) coil array having multiple coil channels. An inverse operator is formed from autocalibration scan (ACS) data, and is applied to the acquired scan data in order to produce reconstruction coefficients. Missing k-space lines in the undersampled scan data are synthesized by interpolating k-space lines in the acquired scan data using the reconstruction coefficients. From the acquired scan data and the synthesized missing k-space lines, individual coil images are reconstructed and combined to form an image of the subject.
FILED	Monday, April 19, 2010
APPL NO	12/762922
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/309
VIEW PATENT	@ USPTO: Full Text PDF

08400697 — Scanner apparatus having electromagnetic radiation devices coupled to MEMS actuators

US 08400697	Smith et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Stephen W. Smith (Durham, North Carolina); Kenneth L. Gentry (Durham, North Carolina); Jason Zara (Vienna, Virginia); Stephen M. Bobbio (Wake Forest, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina); University of North Carolina at Charlotte (Charlotte, North Carolina)
INVENTOR(S)	Stephen W. Smith (Durham, North Carolina); Kenneth L. Gentry (Durham, North Carolina); Jason Zara (Vienna, Virginia); Stephen M. Bobbio (Wake Forest, North Carolina)
ABSTRACT	A disclosed optical scanner apparatus can include a member having spaced apart proximal and distal portions. An optical scanning device can be configured to direct optical radiation, which is moveably coupled to the proximal portion of the member and can be configured to rotate in a plane of movement to a first position to direct the optical radiation along a first path and can be configured to rotate in the plane of movement to a second position to direct the optical radiation along a second path. A MicroElectroMechanical Systems (MEMS) actuator can be coupled to the optical scanning device, where the MEMS actuator can be configured to move in a first direction to move the optical scanning device to the first position and can be configured to move in a second direction to move the optical scanning device to the second position. The MEMS actuator can have proximal and distal portions, where the distal portion of the MEMS actuator is coupled to the proximal portion of the member and the proximal portion of the MEMS actuator is coupled to the optical scanning device. Other scanner apparatus are disclosed.
FILED	Friday, March 12, 2010
APPL NO	12/723368
ART UNIT	2872 — Optics
CURRENT CPC	Optical: Systems and elements 359/198.100
VIEW PATENT	@ USPTO: Full Text PDF

08401257 — Methods, systems and computer program products for processing images generated using Fourier domain optical coherence tomography (FDOCT)

US 08401257	Izatt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Joseph A. Izatt (Raleigh, North Carolina); Eric L. Buckland (Hickory, North Carolina); Bennett R. Groshong (Raleigh, North Carolina); Bradley A. Bower (Hillsborough, North Carolina)
ASSIGNEE(S)	Bioptigen, Inc. (Durham, North Carolina)
INVENTOR(S)	Joseph A. Izatt (Raleigh, North Carolina); Eric L. Buckland (Hickory, North Carolina); Bennett R. Groshong (Raleigh, North Carolina); Bradley A. Bower (Hillsborough, North Carolina)
ABSTRACT	Methods, systems and computer program products for managing frequency domain optical coherence tomography (FDOCT) image resolution. A spectrum used to acquire an image of a subject is calibrated and default dispersion correction parameters are set. Default dispersion management parameters associated with a region of the image of the subject are also set. The image of the subject is acquires after setting the default dispersion correction parameters and the default dispersion management parameters. A quality of the acquired image is compared to a quality metric for the acquired image. The dispersion correction parameters are adjusted if the quality of the acquired image does not meet or exceed the quality metric for the acquired image. The acquired image is reprocesses based on the adjusted dispersion correction parameters. The steps of comparing, adjusting and reprocessing are repeated until the acquired image meets or exceeds the quality metric for the acquired image.
FILED	Friday, January 18, 2008
APPL NO	12/016352
ART UNIT	2881 — Optics
CURRENT CPC	Image analysis 382/128
VIEW PATENT	@ USPTO: Full Text PDF

08401276 — 3-D reconstruction and registration

US 08401276	Choe et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Tae Eun Choe (Reston, Virginia); Gerard Medioni (Los Angeles, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Tae Eun Choe (Reston, Virginia); Gerard Medioni (Los Angeles, California)
ABSTRACT	Generating three-dimensional information can include accessing multiple different images of an object taken by one or more cameras; selecting one of the accessed images as a reference image; identifying corresponding features between the reference image and one or more different ones of the accessed images; determining first camera pose information for each accessed image based on one or more of the corresponding features, each first camera pose information indicative of a relationship between an imaging device and the object; determining a first three-dimensional structure of the object based on first camera pose information of two of the accessed images; and generating a second three-dimensional structure and a second camera pose information for each accessed image based on the first three-dimensional structure and the first camera pose information for each accessed image.
FILED	Wednesday, May 20, 2009
APPL NO	12/469638
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/154
VIEW PATENT	@ USPTO: Full Text PDF

08401609 — System, method and applications involving identification of biological circuits such as neurological characteristics

US 08401609	Deisseroth et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) NIH Office of the Director (NIHOD)
APPLICANT(S)	Karl Deisseroth (Palo Alto, California); Raag D. Airan (Menlo Park, California); Leslie A. Meltzer (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Karl Deisseroth (Palo Alto, California); Raag D. Airan (Menlo Park, California); Leslie A. Meltzer (Palo Alto, California)
ABSTRACT	Various aspects are directed to systems and methods for assessing neural activity of a neural region having multiple subfields. In certain embodiments, a method includes evoking a cellular electrical response in at least one subfield due to neural activity in the neural region, capturing image data of the electrical response at a level sufficiently detailed in space and time to differentiate between polarization-based events of two respective portions of the subfield, and then assessing neural activity by correlating space and time information, from the captured data, for the two respective portions of the sub-field. Other more specific aspects of the invention involve different preparation and neural stimulation approaches which can vary depending on the application.
FILED	Thursday, February 14, 2008
APPL NO	12/031651
ART UNIT	3768 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Surgery 6/407
VIEW PATENT	@ USPTO: Full Text PDF

08401635 — Device and method using integrated neuronal cells and an electronic device

US 08401635	Smith et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Douglas H. Smith (Boothwyn, Pennsylvania); Bryan Pfister (Newtown, Pennsylvania); David F. Meaney (Media, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Douglas H. Smith (Boothwyn, Pennsylvania); Bryan Pfister (Newtown, Pennsylvania); David F. Meaney (Media, Pennsylvania)
ABSTRACT	The present invention provides a device of integrated neuronal cells interfaced with an electronic device and a method of producing the same.
FILED	Thursday, June 09, 2011
APPL NO	13/156927
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/2
VIEW PATENT	@ USPTO: Full Text PDF

08401799 — Antibody design using anti-lipid antibody crystal structures

US 08401799	Sabbadini et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Roger A. Sabbadini (Lakeside, California); Tom Huxford (San Diego, California); Jonathan Michael Wojciak (Encinitas, California)
ASSIGNEE(S)	Lpath, Inc. (San Diego, California)
INVENTOR(S)	Roger A. Sabbadini (Lakeside, California); Tom Huxford (San Diego, California); Jonathan Michael Wojciak (Encinitas, California)
ABSTRACT	Methods for designing optimized antibodies, including optimized humainized or human antibodies, to target bioactive lipids are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Antibodies produced by these methods are also provided, as are methods for using them.
FILED	Friday, June 04, 2010
APPL NO	12/794668
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

08397356 — Triple bar, high efficiency mechanical sealer

US 08397356	Pak et al.
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM) Savannah River National Laboratory (SRNL) Federally Funded Research and Development Center (FFRDC) Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)	Donald J. Pak (Martinez, Georgia); Samantha A. Hawkins (Athens, Georgia); John E. Young (Aiken, South Carolina)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Donald J. Pak (Martinez, Georgia); Samantha A. Hawkins (Athens, Georgia); John E. Young (Aiken, South Carolina)
ABSTRACT	A clamp with a bottom clamp bar that has a planar upper surface is provided. The clamp may also include a top clamp bar connected to the bottom clamp bar, and a pressure distribution bar between the top clamp bar and the bottom clamp bar. The pressure distribution bar may have a planar lower surface in facing relation to the upper surface of the bottom clamp bar. An object is capable of being disposed in a clamping region between the upper surface and the lower surface. The width of the planar lower surface may be less than the width of the upper surface within the clamping region. Also, the pressure distribution bar may be capable of being urged away from the top clamp bar and towards the bottom clamp bar.
FILED	Tuesday, November 10, 2009
APPL NO	12/590518
ART UNIT	3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Buckles, buttons, clasps, etc. 024/569
VIEW PATENT	@ USPTO: Full Text PDF

08397448 — Photovoltaic panel clamp

US 08397448	Brown et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Malcolm P. Brown (San Francisco, California); Margaret Birmingham Mittan (Oakland, California); Robert H. J. Miros (Fairfax, California); Robert Stancel (Los Altos Hills, California)
ASSIGNEE(S)	SunLink Corporation (San Rafael, California)
INVENTOR(S)	Malcolm P. Brown (San Francisco, California); Margaret Birmingham Mittan (Oakland, California); Robert H. J. Miros (Fairfax, California); Robert Stancel (Los Altos Hills, California)
ABSTRACT	A photovoltaic panel clamp includes an upper and lower section. The interface between the assembled clamp halves and the module edge is filled by a flexible gasket material, such as EPDM rubber. The gasket preferably has small, finger like protrusions that allow for easy insertion onto the module edge while being reversed makes it more difficult to remove them from the module once installed. The clamp includes mounting posts or an integral axle to engage a bracket. The clamp also may include a locking tongue to secure the clamp to a bracket.
FILED	Wednesday, February 29, 2012
APPL NO	13/408264
ART UNIT	3633 — Static Structures, Supports and Furniture
CURRENT CPC	Static structures 052/173.300
VIEW PATENT	@ USPTO: Full Text PDF

08397506 — Turbo-alternator-compressor design for supercritical high density working fluids

US 08397506	Wright et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Steven A. Wright (Albuquerque, New Mexico); Robert L. Fuller (Conifer, Colorado)
ASSIGNEE(S)
INVENTOR(S)	Steven A. Wright (Albuquerque, New Mexico); Robert L. Fuller (Conifer, Colorado)
ABSTRACT	Techniques for generating power are provided. Such techniques involve a thermodynamic system including a housing, a turbine positioned in a turbine cavity of the housing, a compressor positioned in a compressor cavity of the housing, and an alternator positioned in a rotor cavity between the turbine and compressor cavities. The compressor has a high-pressure face facing an inlet of the compressor cavity and a low-pressure face on an opposite side thereof. The alternator has a rotor shaft operatively connected to the turbine and compressor, and is supported in the housing by bearings. Ridges extending from the low-pressure face of the compressor may be provided for balancing thrust across the compressor. Seals may be positioned about the alternator for selectively leaking fluid into the rotor cavity to reduce the temperature therein.
FILED	Wednesday, June 03, 2009
APPL NO	12/477259
ART UNIT	3748 — Static Structures, Supports and Furniture
CURRENT CPC	Power plants 060/643
VIEW PATENT	@ USPTO: Full Text PDF

08397508 — Metal ferrite spinel energy storage devices and methods for making and using same

US 08397508	Weimer et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Alan W. Weimer (Niwot, Colorado); Christopher Perkins (Boulder, Colorado); Jonathan Scheffe (Westminster, Colorado); Steven M. George (Boulder, Colorado); Paul Lichty (Westminster, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S)	Alan W. Weimer (Niwot, Colorado); Christopher Perkins (Boulder, Colorado); Jonathan Scheffe (Westminster, Colorado); Steven M. George (Boulder, Colorado); Paul Lichty (Westminster, Colorado)
ABSTRACT	1-100 nm metal ferrite spinel coatings are provided on substrates, preferably by using an atomic layer deposition process. The coatings are able to store energy such as solar energy, and to release that stored energy, via a redox reaction. The coating is first thermally or chemically reduced. The reduced coating is then oxidized in a second step to release energy and/or hydrogen, carbon monoxide or other reduced species.
FILED	Wednesday, November 05, 2008
APPL NO	12/741492
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Power plants 060/721
VIEW PATENT	@ USPTO: Full Text PDF

08397551 — Passive blast pressure sensor

US 08397551	King et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Michael J. King (Livermore, California); Roberto J. Sanchez (Pleasanton, California); William C. Moss (San Mateo, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Michael J. King (Livermore, California); Roberto J. Sanchez (Pleasanton, California); William C. Moss (San Mateo, California)
ABSTRACT	A passive blast pressure sensor for detecting blast overpressures of at least a predetermined minimum threshold pressure. The blast pressure sensor includes a piston-cylinder arrangement with one end of the piston having a detection surface exposed to a blast event monitored medium through one end of the cylinder and the other end of the piston having a striker surface positioned to impact a contact stress sensitive film that is positioned against a strike surface of a rigid body, such as a backing plate. The contact stress sensitive film is of a type which changes color in response to at least a predetermined minimum contact stress which is defined as a product of the predetermined minimum threshold pressure and an amplification factor of the piston. In this manner, a color change in the film arising from impact of the piston accelerated by a blast event provides visual indication that a blast overpressure encountered from the blast event was not less than the predetermined minimum threshold pressure.
FILED	Friday, April 30, 2010
APPL NO	12/770983
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/35.140
VIEW PATENT	@ USPTO: Full Text PDF

08398738 — Biochar production method and composition therefrom

US 08398738	Lee et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	James W. Lee (Cockeysville, Maryland); Archibald C. Buchanan, III (Knoxville, Tennessee); Barbara R. Evans (Oak Ridge, Tennessee); Michelle K. Kidder (Clinton, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	James W. Lee (Cockeysville, Maryland); Archibald C. Buchanan, III (Knoxville, Tennessee); Barbara R. Evans (Oak Ridge, Tennessee); Michelle K. Kidder (Clinton, Tennessee)
ABSTRACT	The invention is directed to a method for producing an oxygenated biochar material possessing a cation-exchanging property, wherein a biochar source is reacted with one or more oxygenating compounds in such a manner that the biochar source homogeneously acquires oxygen-containing cation-exchanging groups in an incomplete combustion process. The invention is also directed to oxygenated biochar compositions and soil formulations containing the oxygenated biochar material.
FILED	Wednesday, January 13, 2010
APPL NO	12/686831
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemistry: Fertilizers 071/54
VIEW PATENT	@ USPTO: Full Text PDF

08398824 — Apparatus for hydrocarbon extraction

US 08398824	Bohnert et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Kansas City National Security Campus (KCNSC) NNSA Critical Mission Site Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S)	George W. Bohnert (Harrisonville, Missouri); Galen G. Verhulst (Kansas City, Missouri)
ASSIGNEE(S)	Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S)	George W. Bohnert (Harrisonville, Missouri); Galen G. Verhulst (Kansas City, Missouri)
ABSTRACT	Systems and methods for hydrocarbon extraction from hydrocarbon-containing material. Such systems and methods relate to extracting hydrocarbon from hydrocarbon-containing material employing a non-aqueous extractant. Additionally, such systems and methods relate to recovering and reusing non-aqueous extractant employed for extracting hydrocarbon from hydrocarbon-containing material.
FILED	Tuesday, May 11, 2010
APPL NO	12/777428
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Mineral oils: Apparatus 196/14.520
VIEW PATENT	@ USPTO: Full Text PDF

08398839 — System for particle concentration and detection

US 08398839	Morales et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Alfredo M. Morales (Livermore, California); Josh A. Whaley (Livermore, California); Mark D. Zimmerman (Livermore, California); Ronald F. Renzi (Tracy, California); Huu M. Tran (San Jose, California); Scott M. Maurer (Haymarket, Virginia); William D. Munslow (Gainesville, Virginia)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Alfredo M. Morales (Livermore, California); Josh A. Whaley (Livermore, California); Mark D. Zimmerman (Livermore, California); Ronald F. Renzi (Tracy, California); Huu M. Tran (San Jose, California); Scott M. Maurer (Haymarket, Virginia); William D. Munslow (Gainesville, Virginia)
ABSTRACT	A new microfluidic system comprising an automated prototype insulator-based dielectrophoresis (iDEP) triggering microfluidic device for pathogen monitoring that can eventually be run outside the laboratory in a real world environment has been used to demonstrate the feasibility of automated trapping and detection of particles. The system broadly comprised an aerosol collector for collecting air-borne particles, an iDEP chip within which to temporarily trap the collected particles and a laser and fluorescence detector with which to induce a fluorescence signal and detect a change in that signal as particles are trapped within the iDEP chip.
FILED	Thursday, June 03, 2010
APPL NO	12/793370
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Electrical and wave energy 24/547
VIEW PATENT	@ USPTO: Full Text PDF

08398840 — Capacitive de-ionization electrode

US 08398840	Daily, III
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	William D. Daily, III (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	William D. Daily, III (Livermore, California)
ABSTRACT	An electrode “cell” for use in a capacitive deionization (CDI) reactor consists of the electrode support structure, a non-reactive conductive material, the electrode accompaniment or substrate and a flow through screen/separator. These “layers” are repeated and the electrodes are sealed together with gaskets between two end plates to create stacked sets of alternating anode and cathode electrodes in the CDI reactor.
FILED	Thursday, July 31, 2008
APPL NO	12/183331
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Electrical and wave energy 24/554
VIEW PATENT	@ USPTO: Full Text PDF

08398842 — Electrochemical process for the preparation of nitrogen fertilizers

US 08398842	Aulich et al.
FUNDED BY	Department of Energy (DOE) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Ted R. Aulich (Grand Forks, North Dakota); Edwin S. Olson (Grand Forks, North Dakota); Junhua Jiang (Grand Forks, North Dakota)
ASSIGNEE(S)	Energy and Environmental Research Center Foundation (Grand Forks, California)
INVENTOR(S)	Ted R. Aulich (Grand Forks, North Dakota); Edwin S. Olson (Grand Forks, North Dakota); Junhua Jiang (Grand Forks, North Dakota)
ABSTRACT	The present invention provides methods and apparatus for the preparation of nitrogen fertilizers including ammonium nitrate, urea, urea-ammonium nitrate, and/or ammonia utilizing a source of carbon, a source of nitrogen, and/or a source of hydrogen. Implementing an electrolyte serving as ionic charge carrier, (1) ammonium nitrate is produced via the reduction of a nitrogen source at the cathode and the oxidation of a nitrogen source at the anode; (2) urea or its isomers are produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source; (3) ammonia is produced via the reduction of nitrogen source at the cathode and the oxidation of a hydrogen source at the anode; and (4) urea-ammonium nitrate is produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source, and anodic oxidation of a nitrogen source. The electrolyte can be solid.
FILED	Thursday, March 15, 2012
APPL NO	13/420979
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/551
VIEW PATENT	@ USPTO: Full Text PDF

08398872 — Method for preparing ultraflat, atomically perfect areas on large regions of a crystal surface by heteroepitaxy deposition

US 08398872	El Gabaly et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Farid El Gabaly (Berkeley, California); Andreas K. Schmid (Berkeley, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Farid El Gabaly (Berkeley, California); Andreas K. Schmid (Berkeley, California)
ABSTRACT	A novel method of forming large atomically flat areas is described in which a crystalline substrate having a stepped surface is exposed to a vapor of another material to deposit a material onto the substrate, which material under appropriate conditions self arranges to form 3D islands across the substrate surface. These islands are atomically flat at their top surface, and conform to the stepped surface of the substrate below at the island-substrate interface. Thereafter, the deposited materials are etched away, in the etch process the atomically flat surface areas of the islands transferred to the underlying substrate. Thereafter the substrate may be cleaned and annealed to remove any remaining unwanted contaminants, and eliminate any residual defects that may have remained in the substrate surface as a result of pre-existing imperfections of the substrate.
FILED	Tuesday, March 10, 2009
APPL NO	12/921562
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Etching a substrate: Processes 216/37
VIEW PATENT	@ USPTO: Full Text PDF

08399109 — Organic electronic devices using phthalimide compounds

US 08399109	Hassan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Azad M. Hassan (Los Angeles, California); Mark E. Thompson (Anaheim, California)
ASSIGNEE(S)	The University of Southern California (Los Angeles, California)
INVENTOR(S)	Azad M. Hassan (Los Angeles, California); Mark E. Thompson (Anaheim, California)
ABSTRACT	Organic electronic devices comprising a phthalimide compound. The phthalimide compounds disclosed herein are electron transporters with large HOMO-LUMO gaps, high triplet energies, large reduction potentials, and/or thermal and chemical stability. As such, these phthalimide compounds are suitable for use in any of various organic electronic devices, such as OLEDs and solar cells. In an OLED, the phthalimide compounds may serve various functions, such as a host in the emissive layer, as a hole blocking material, or as an electron transport material. In a solar cell, the phthalimide compounds may serve various functions, such as an exciton blocking material. Various examples of phthalimide compounds which may be suitable for use in the present invention are disclosed.
FILED	Friday, September 21, 2012
APPL NO	13/624161
ART UNIT	1786 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/690
VIEW PATENT	@ USPTO: Full Text PDF

08399217 — High density growth of T7 expression strains with auto-induction option

US 08399217	Studier
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	F. William Studier (Stony Brook, New York)
ASSIGNEE(S)	Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S)	F. William Studier (Stony Brook, New York)
ABSTRACT	A method for promoting and suppressing auto-induction of transcription of a cloned gene 1 of bacteriophage T7 in cultures of bacterial cells grown batchwise is disclosed. The transcription is under the control of a promoter whose activity can be induced by an exogenous inducer whose ability to induce said promoter is dependent on the metabolic state of said bacterial cells.
FILED	Friday, April 27, 2007
APPL NO	11/741282
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/69.100
VIEW PATENT	@ USPTO: Full Text PDF

08399688 — Production of levulinic acid, furfural, and gamma valerolactone from C₅and C₆carbohydrates in mono- and biphasic systems using gamma-valerolactone as a solvent

US 08399688	Dumesic et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	James A. Dumesic (Verona, Wisconsin); David Martin Alonso (Madison, Wisconsin); Elif I. Gürbüz (Madison, Wisconsin); Stephanie G. Wettstein (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	James A. Dumesic (Verona, Wisconsin); David Martin Alonso (Madison, Wisconsin); Elif I. Gürbüz (Madison, Wisconsin); Stephanie G. Wettstein (Madison, Wisconsin)
ABSTRACT	A method to make levulinic acid (LA), furfural, or gamma-valerolactone (GVL). React cellulose (and/or other C₆carbohydrates) or xylose (and/or other C₅carbohydrates) or combinations thereof in a monophasic reaction medium comprising GVL and an acid; or (ii) a biphasic reaction system comprising an organic layer comprising GVL, and a substantially immiscible aqueous layer. At least a portion of the cellulose (and/or other C₆carbohydrates), if present, is converted to LA and at least a portion of the xylose (and/or other C₅carbohydrates), if present, is converted into furfural.
FILED	Thursday, April 12, 2012
APPL NO	13/445643
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Organic compounds 549/326
VIEW PATENT	@ USPTO: Full Text PDF

08399761 — Organic photovoltaic device with interfacial layer and method of fabricating same

US 08399761	Marks et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE)
APPLICANT(S)	Tobin J. Marks (Evanston, Illinois); Alexander W. Hains (Lakewood, Colorado)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Tobin J. Marks (Evanston, Illinois); Alexander W. Hains (Lakewood, Colorado)
ABSTRACT	An organic photovoltaic device and method of forming same. In one embodiment, the organic photovoltaic device has an anode, a cathode, an active layer disposed between the anode and the cathode; and an interfacial layer disposed between the anode and the active layer, the interfacial layer comprising 5,5′-bis[(p-trichlorosilylpropylphenyl)phenylamino]-2,2′-bithiophene (PABTSi₂).
FILED	Friday, April 30, 2010
APPL NO	12/771376
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Batteries: Thermoelectric and photoelectric 136/263
VIEW PATENT	@ USPTO: Full Text PDF

08399939 — Color selective photodetector and methods of making

US 08399939	Walker et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Energy (DOE)
APPLICANT(S)	Brian J. Walker (Somerville, Massachusetts); August Dorn (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Brian J. Walker (Somerville, Massachusetts); August Dorn (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts)
ABSTRACT	A photoelectric device, such as a photodetector, can include a semiconductor nanowire electrostatically associated with a J-aggregate. The J-aggregate can facilitate absorption of a desired wavelength of light, and the semiconductor nanowire can facilitate charge transport. The color of light detected by the device can be chosen by selecting a J-aggregate with a corresponding peak absorption wavelength.
FILED	Friday, December 03, 2010
APPL NO	12/960090
ART UNIT	2891 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/414
VIEW PATENT	@ USPTO: Full Text PDF

08400064 — Zener diode protection network in submount for LEDs connected in series

US 08400064	Wei et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Yajun Wei (Sunnyvale, California); William D. Collins, III (San Jose, California); Daniel A. Steigerwald (Cupertino, California)
ASSIGNEE(S)	Koninklijke Philips Electronics N.V. (Eindhoven, Netherlands); Philips Lumileds Lighting Company, LLC (San Jose, California)
INVENTOR(S)	Yajun Wei (Sunnyvale, California); William D. Collins, III (San Jose, California); Daniel A. Steigerwald (Cupertino, California)
ABSTRACT	A transient voltage suppressor circuit is disclosed for a plurality (N) of LEDs connected in series. Only one zener diode is created for connection to each node between LEDs, and a pair of zener diodes (the “end” zener diodes) are connected to the two pins (anode and cathode pads) of the series string. Therefore, only N+1 zener diodes are used. The end zener diodes (Q1 and Qn+1) effectively create back-to-back zener diodes across the two pins since the zener diodes share a common p+ substrate. The n+ regions of the end zener diodes Q1 and Qn+1 have the highest breakdown voltage requirement and must be placed relatively far apart. Adjacent n+ regions of the intermediate zener diodes have a much lower breakdown voltage requirement so may be located close together. The zener diodes may be placed within a very small footprint or can be larger for better suppressor performance.
FILED	Wednesday, September 09, 2009
APPL NO	12/556054
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Electric lamp and discharge devices: Systems 315/122
VIEW PATENT	@ USPTO: Full Text PDF

08400071 — LED lamp power management system and method

US 08400071	Gaines et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	James Gaines (Glen Ellyn, New York); Bernd Clauberg (Schaumburg, Illinois); Josephus A. M. Van Erp (Asten, Netherlands)
ASSIGNEE(S)	Koninklijke Philips Electronics N.V. (Eindhoven, Netherlands)
INVENTOR(S)	James Gaines (Glen Ellyn, New York); Bernd Clauberg (Schaumburg, Illinois); Josephus A. M. Van Erp (Asten, Netherlands)
ABSTRACT	An LED lamp power management system and method including an LED lamp having an LED controller 58; a plurality of LED channels 60 operably connected to the LED controller 58, each of the plurality of LED channels 60 having a channel switch 62 in series with at least one shunted LED circuit 83, the shunted LED circuit 83 having a shunt switch 68 in parallel with an LED source 80. The LED controller 58 reduces power loss in one of the channel switch 62 and the shunt switch 68 when LED lamp electronics power loss (P_loss) exceeds an LED lamp electronics power loss limit (P_lim); and each of the channel switches 62 receives a channel switch control signal 63 from the LED controller 58 and each of the shunt switches 68 receives a shunt switch control signal 69 from the LED controller 58.
FILED	Tuesday, December 02, 2008
APPL NO	12/746540
ART UNIT	2821 — Semiconductors/Memory
CURRENT CPC	Electric lamp and discharge devices: Systems 315/247
VIEW PATENT	@ USPTO: Full Text PDF

08400349 — Radar echo processing with partitioned de-ramp

US 08400349	Dubbert et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Dale F. Dubbert (Cedar Crest, New Mexico); Bertice L. Tise (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Dale F. Dubbert (Cedar Crest, New Mexico); Bertice L. Tise (Albuquerque, New Mexico)
ABSTRACT	The spurious-free dynamic range of a wideband radar system is increased by apportioning de-ramp processing across analog and digital processing domains. A chirp rate offset is applied between the received waveform and the reference waveform that is used for downconversion to the intermediate frequency (IF) range. The chirp rate offset results in a residual chirp in the IF signal prior to digitization. After digitization, the residual IF chirp is removed with digital signal processing.
FILED	Tuesday, July 27, 2010
APPL NO	12/844576
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Communications: Directive radio wave systems and devices 342/113
VIEW PATENT	@ USPTO: Full Text PDF

08401142 — Nuclear reactor vessel fuel thermal insulating barrier

US 08401142	Keegan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	C. Patrick Keegan (Latrobe, Pennsylvania); James H. Scobel (Irwin, Pennsylvania); Richard F. Wright (Greenock, Pennsylvania)
ASSIGNEE(S)	Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
INVENTOR(S)	C. Patrick Keegan (Latrobe, Pennsylvania); James H. Scobel (Irwin, Pennsylvania); Richard F. Wright (Greenock, Pennsylvania)
ABSTRACT	The reactor vessel of a nuclear reactor installation which is suspended from the cold leg nozzles in a reactor cavity is provided with a lower thermal insulating barrier spaced from the reactor vessel that has a hemispherical lower section that increases in volume from the center line of the reactor to the outer extent of the diameter of the thermal insulating barrier and smoothly transitions up the side walls of the vessel. The space between the thermal insulating harrier and the reactor vessel forms a chamber which can be flooded with cooling water through passive valving to directly cool the reactor vessel in the event of a severe accident. The passive inlet valve for the cooling water includes a buoyant door that is normally maintained sealed under its own weight and floats open when the cavity is Hooded. Passively opening steam vents are also provided.
FILED	Thursday, May 03, 2007
APPL NO	11/743844
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Induced nuclear reactions: Processes, systems, and elements 376/289
VIEW PATENT	@ USPTO: Full Text PDF

08401710 — Wide-area, real-time monitoring and visualization system

US 08401710	Budhraja et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Vikram S. Budhraja (Los Angeles, California); James D. Dyer (La Mirada, California); Carlos A. Martinez Morales (Upland, California)
ASSIGNEE(S)	Electric Power Group, LLC (Pasadena, California)
INVENTOR(S)	Vikram S. Budhraja (Los Angeles, California); James D. Dyer (La Mirada, California); Carlos A. Martinez Morales (Upland, California)
ABSTRACT	A real-time performance monitoring system for monitoring an electric power grid. The electric power grid has a plurality of grid portions, each grid portion corresponding to one of a plurality of control areas. The real-time performance monitoring system includes a monitor computer for monitoring at least one of reliability metrics, generation metrics, transmission metrics, suppliers metrics, grid infrastructure security metrics, and markets metrics for the electric power grid. The data for metrics being monitored by the monitor computer are stored in a data base, and a visualization of the metrics is displayed on at least one display computer having a monitor. The at least one display computer in one said control area enables an operator to monitor the grid portion corresponding to a different said control area.
FILED	Thursday, September 29, 2011
APPL NO	13/249152
ART UNIT	2121 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Generic control systems or specific applications 7/291
VIEW PATENT	@ USPTO: Full Text PDF

08401797 — Method for predicting enzyme-catalyzed reactions

US 08401797	Hlavacek et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	William S. Hlavacek (Santa Fe, New Mexico); Clifford J. Unkefer (Los Alamos, New Mexico); Fangping Mu (Los Alamos, New Mexico); Pat J. Unkefer (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	William S. Hlavacek (Santa Fe, New Mexico); Clifford J. Unkefer (Los Alamos, New Mexico); Fangping Mu (Los Alamos, New Mexico); Pat J. Unkefer (Los Alamos, New Mexico)
ABSTRACT	The reactivity of given metabolites is assessed using selected empirical atomic properties in the potential reaction center. Metabolic reactions are represented as biotransformation rules. These rules are generalized from the patterns in reactions. These patterns are not unique to reactants but are widely distributed among metabolites. Using a metabolite database, potential substructures are identified in the metabolites for a given biotransformation. These substructures are divided into reactants or non-reactants, depending on whether they participate in the biotransformation or not. Each potential substructure is then modeled using descriptors of the topological and electronic properties of atoms in the potential reaction center; molecular properties can also be used. A Support Vector Machine (SVM) or classifier is trained to classify a potential reactant as a true or false reactant using these properties.
FILED	Wednesday, September 26, 2007
APPL NO	11/862103
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

08397549 — System for formation of highly nonlinear pulses

US 08397549	Daraio
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Chiara Daraio (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Chiara Daraio (Pasadena, California)
ABSTRACT	A system supporting the formation and propagation of tunable highly nonlinear pulses using granular chains composed of non-spherical granular systems. Such a system may be used to support the creation of tunable acoustic band gaps in granular crystals formed of particles with different geometries (spherical or not) in which the tunability is achieved by varying the static precompression, type of excitation and/or pulse amplitude in the system.
FILED	Thursday, March 29, 2012
APPL NO	13/434821
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/12.110
VIEW PATENT	@ USPTO: Full Text PDF

08398295 — Magnetic fluid manipulators and methods for their use

US 08398295	Yellen et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	Benjamin B. Yellen (Cary, North Carolina); Gennady Friedman (Richboro, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Benjamin B. Yellen (Cary, North Carolina); Gennady Friedman (Richboro, Pennsylvania)
ABSTRACT	Device and methods for use of these devices to manipulate substantially non-magnetic particles dispersed inside a magnetic fluid by employing a changeable pattern of local magnetic field maxima and minima are provided.
FILED	Friday, January 28, 2005
APPL NO	10/586566
ART UNIT	1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Agitating 366/273
VIEW PATENT	@ USPTO: Full Text PDF

08398541 — Interactive user interfaces for robotic minimally invasive surgical systems

US 08398541	DiMaio et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Simon P. DiMaio (Sunnyvale, California); Christopher J. Hasser (Los Altos, California); Russell H. Taylor (Severna Park, Maryland); David Q. Larkin (Menlo Park, California); Peter Kazanzides (Towson, Maryland); Anton Deguet (Baltimore, Maryland); Bálazs Peter Vágvölgyi (Baltimore, Maryland); Joshua Leven (Astoria, New York)
ASSIGNEE(S)	Intuitive Surgical Operations, Inc. (Sunnyvale, California); Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Simon P. DiMaio (Sunnyvale, California); Christopher J. Hasser (Los Altos, California); Russell H. Taylor (Severna Park, Maryland); David Q. Larkin (Menlo Park, California); Peter Kazanzides (Towson, Maryland); Anton Deguet (Baltimore, Maryland); Bálazs Peter Vágvölgyi (Baltimore, Maryland); Joshua Leven (Astoria, New York)
ABSTRACT	In one embodiment of the invention, a method for a minimally invasive surgical system is disclosed. The method includes capturing and displaying camera images of a surgical site on at least one display device at a surgeon console; switching out of a following mode and into a masters-as-mice (MaM) mode; overlaying a graphical user interface (GUI) including an interactive graphical object onto the camera images; and rendering a pointer within the camera images for user interactive control. In the following mode, the input devices of the surgeon console may couple motion into surgical instruments. In the MaM mode, the input devices interact with the GUI and interactive graphical objects. The pointer is manipulated in three dimensions by input devices having at least three degrees of freedom. Interactive graphical objects are related to physical objects in the surgical site or a function thereof and are manipulatable by the input devices.
FILED	Monday, August 11, 2008
APPL NO	12/189615
ART UNIT	3779 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Surgery 6/111
VIEW PATENT	@ USPTO: Full Text PDF

08398909 — Dry adhesives and methods of making dry adhesives

US 08398909	Sitti et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Metin Sitti (Pittsburgh, Pennsylvania); Burak Aksak (Pittsburgh, Pennsylvania); Michael Murphy (Waltham, Massachusetts)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	Metin Sitti (Pittsburgh, Pennsylvania); Burak Aksak (Pittsburgh, Pennsylvania); Michael Murphy (Waltham, Massachusetts)
ABSTRACT	Dry adhesives and methods of making dry adhesives including a method of making a dry adhesive including applying a liquid polymer to the second end of a stem, contacting the liquid polymer on the stem with a tip shaping surface, bending the stem relative to the backing layer while contacting the liquid polymer on the stem with the tip shaping surface, curing the liquid polymer to form a tip on the second end of the stem while bending the stem relative to the backing layer and while contacting the liquid polymer on the stem with the tip shaping surface, and removing the tip from the tip shaping surface after the liquid polymer cures.
FILED	Friday, September 18, 2009
APPL NO	12/562643
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Plastic and nonmetallic article shaping or treating: Processes 264/255
VIEW PATENT	@ USPTO: Full Text PDF

08398992 — Methods and compositions for polytopic vaccination

US 08398992	Deem et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)	Michael W Deem (West University Place, Texas); Jeong-Man Park (Seoul, South Korea); Hao Zhou (New York, New York)
ASSIGNEE(S)	Polytopos LLC (West University Place, Texas)
INVENTOR(S)	Michael W Deem (West University Place, Texas); Jeong-Man Park (Seoul, South Korea); Hao Zhou (New York, New York)
ABSTRACT	The present invention relates to therapeutic and prophylactic methods for treating or preventing an infectious disease in a subject by stimulating or enhancing an immune response against an infectious agent causing the disease. The methods comprise administering to the subject a plurality of compositions, each composition being administered to a different site of the subject, wherein each site is, or substantially drains to, an anatomically distinct lymph node, a group of lymph nodes, a nonencapsulated cluster of lymphoid tissue, or the spleen. Each composition comprises at least one antigenic molecule having one or more epitopes of the same infectious agent or a strain thereof. The antigenic molecules of each composition comprise in aggregate a set of epitopes distinct from that of any other composition that is administered to the subject.
FILED	Thursday, December 22, 2011
APPL NO	13/335655
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/202.100
VIEW PATENT	@ USPTO: Full Text PDF

08399047 — Multifunctional CVD coatings

US 08399047	Lahann et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Joerg Lahann (Ann Arbor, Michigan); Yaseen Elkasabi (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of The Univeristy of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Joerg Lahann (Ann Arbor, Michigan); Yaseen Elkasabi (Ann Arbor, Michigan)
ABSTRACT	Multifunctional reactive polymers created by chemical vapor deposition (CVD) and methods of making such polymeric systems are provided. Such polymers provide multifunctional surfaces which can present two or more different molecules (e.g. biological ligands) in controlled ratios. Polymers may include compositional gradients allowing attached ligands to be presented as continuous gradients across a surface. The polymer compositions are modularly designable and applicable to a wider range of applications, including biomedical devices and diagnostic systems.
FILED	Monday, March 24, 2008
APPL NO	12/054171
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Coating processes 427/97.500
VIEW PATENT	@ USPTO: Full Text PDF

08399057 — Ordered vertically oriented porous inorganic films produced through solution processing

US 08399057	Tolbert et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Sarah H. Tolbert (Los Angeles, California); Erik K. Richman (Gibsonia, Pennsylvania)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Sarah H. Tolbert (Los Angeles, California); Erik K. Richman (Gibsonia, Pennsylvania)
ABSTRACT	Porous films with straight pores oriented normal to the plane of the films are produced through solution processing techniques. The production takes advantage of inorganic-surfactant or inorganic-polymer co-assembly and a patterned substrate. The patterned substrate, which is also produced via solution phase self-assembly, forces vertical orientation in a hexagonal cylinder system with no practical limits in substrate size or type. This provides a route to vertically oriented inorganic pores with a pitch ranging from 3 nm to over 15 nm and pore sizes ranging from 2 nm to over 12 nm. The size is tuned by choice the choice of organic templating agents and the deposition conditions. The pores can be produced with or without a capping layer which can be used to seal the nanopores.
FILED	Thursday, June 08, 2006
APPL NO	11/449465
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/271
VIEW PATENT	@ USPTO: Full Text PDF

08399339 — Nanosensors

US 08399339	Lieber et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF)
APPLICANT(S)	Charles M. Lieber (Lexington, Massachusetts); Hongkun Park (Lexington, Massachusetts); Qingqiao Wei (Corvallis, Oregon); Yi Cui (Sunnyvale, California); Wenjie Liang (Oakland, California)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Charles M. Lieber (Lexington, Massachusetts); Hongkun Park (Lexington, Massachusetts); Qingqiao Wei (Corvallis, Oregon); Yi Cui (Sunnyvale, California); Wenjie Liang (Oakland, California)
ABSTRACT	Electrical devices comprised of nanowires are described, along with methods of their manufacture and use. The nanowires can be nanotubes and nanowires. The surface of the nanowires may be selectively functionalized Nanodetector devices are described.
FILED	Monday, April 11, 2011
APPL NO	13/083817
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/478
VIEW PATENT	@ USPTO: Full Text PDF

08399751 — Functional abiotic nanosystems

US 08399751	Lu et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Siyuan Lu (Los Angeles, California); Anupam Madhukar (Arcadia, California); Mark S. Humayun (Glendale, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Siyuan Lu (Los Angeles, California); Anupam Madhukar (Arcadia, California); Mark S. Humayun (Glendale, California)
ABSTRACT	The invention relates to imparting photoreactivity to target cells, e.g., retinal cells, by introducing photoresponsive functional abiotic nanosystems (FANs), nanometer-scale semiconductor/metal or semiconductor/semiconductor hetero-junctions that in this case include a photovoltaic effect. The invention further provides methods of making and using FANs, where the hetero-junctions bear surface functionalization that localizes them in cell membranes. Illumination of these hetero-junctions incorporated in cell membranes generates photovoltages that depolarize the membranes, such as those of nerve cells, in which FANs photogenerate action potentials. Incorporating FANs into the cells of a retina with damaged photoreceptor cells reintroduces photoresponsiveness to the retina, so that light creates action potentials that the brain interprets as sight.
FILED	Thursday, June 12, 2008
APPL NO	12/138289
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Nanotechnology 977/925
VIEW PATENT	@ USPTO: Full Text PDF

08400018 — Wireless energy transfer with high-Q at high efficiency

US 08400018	Joannopoulos et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ABSTRACT	Described herein are embodiments of a source high-Q resonator optionally coupled to an energy source, and a second high-Q resonator, optionally coupled to an energy drain that may be located a distance from the source resonator. The source resonator and the second resonator may be coupled to provide κ/sqrt(Γ₁Γ₂)>0.2 via near-field wireless energy transfer among the source resonator and the second resonator.
FILED	Wednesday, December 16, 2009
APPL NO	12/639962
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/104
VIEW PATENT	@ USPTO: Full Text PDF

08400019 — Wireless energy transfer with high-Q from more than one source

US 08400019	Joannopoulos et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ABSTRACT	Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, a second source high-Q resonator, optionally coupled to an energy source, and a third high-Q resonator, optionally coupled to an energy drain, where at least one of the source resonators and the third resonator may be coupled to transfer electromagnetic energy from at least one of the said source resonators to said third resonator.
FILED	Wednesday, December 16, 2009
APPL NO	12/639966
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/104
VIEW PATENT	@ USPTO: Full Text PDF

08400020 — Wireless energy transfer with high-Q devices at variable distances

US 08400020	Joannopoulos et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ABSTRACT	Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, and a second high-Q resonator, optionally coupled to an energy drain that may be located a variable distance from the source resonator. The source resonator and the second resonator may be coupled to transfer electromagnetic energy from said source resonator to said second resonator over a distance D that is smaller than each of the resonant wavelengths λ₁and λ₂corresponding to the resonant frequencies ω₁and ω₂, respectively.
FILED	Wednesday, December 16, 2009
APPL NO	12/639967
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/104
VIEW PATENT	@ USPTO: Full Text PDF

08400021 — Wireless energy transfer with high-Q sub-wavelength resonators

US 08400021	Joannopoulos et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ABSTRACT	Described herein are embodiments of transferring electromagnetic energy that includes a first electromagnetic resonator structure receiving energy from an external power supply, said first resonator structure may have a first mode with a resonant frequency ω₁, an intrinsic loss rate Γ₁, and a first Q-factor Q₁=ω₁L₁/R_1ohm+R_1rad). A second electromagnetic resonator structure being positioned distal from said first resonator structure and not electrically wired to the first resonator structure, said second resonator structure having a second mode with a resonant frequency ω₂, an intrinsic loss rate Γ₂, and a second Q-factor Q₂=ω₂L₂/(R_2ohm+R_2rad). The electromagnetic energy may be transferred from said first resonator structure to said second resonator structure over a distance D that is smaller than each of the resonant wavelengths λ₁and λ₂corresponding to the resonant frequencies ω₁and ω₂, respectively, where the characteristic sizes of the resonator structures are less than the resonant wavelengths and where Q1>100, Q2>100, R_1ohm>R_1rad, and R_2ohm>R_2rad.
FILED	Wednesday, December 16, 2009
APPL NO	12/639972
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/104
VIEW PATENT	@ USPTO: Full Text PDF

08400022 — Wireless energy transfer with high-Q similar resonant frequency resonators

US 08400022	Joannopoulos et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ABSTRACT	Described herein are embodiments of transferring electromagnetic energy that includes providing a first electromagnetic resonator structure receiving energy from an external power supply, said first resonator structure having a first mode with a resonant frequency ω₁, an intrinsic loss rate Γ₁, and a first Q-factor Q₁=ω₁/(2Γ₁), providing a second electromagnetic resonator structure being positioned distal from said first resonator structure and not electrically wired to the first resonator structure, said second resonator structure having a second mode with a resonant frequency ω₂, an intrinsic loss rate Γ₂, and a second Q-factor Q₂=ω₂/(2Γ₂), and transferring electromagnetic energy from said first resonator structure to said second resonator structure over a distance D that may be smaller than each of the resonant wavelengths λ₁and λ₂corresponding to the resonant frequencies ω₁and ω₂, respectively. The electromagnetic resonator structures may be designed to have Q₁>100 and Q₂>100. The absolute value of the difference of said angular frequencies ω₁and ω₂may be smaller than the magnitude of the coupling rate, κ.
FILED	Wednesday, December 23, 2009
APPL NO	12/646442
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/104
VIEW PATENT	@ USPTO: Full Text PDF

08400023 — Wireless energy transfer with high-Q capacitively loaded conducting loops

US 08400023	Joannopoulos et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ABSTRACT	Described herein are embodiments of a source resonant structure and a device resonant structure, the structures may be capable of performing wireless near-field energy transfer when separated a distance D from each other, where the absolute value of the difference of said angular frequencies w₁and w₂may be smaller than the magnitude of the coupling rate, k, and where at least one of the resonant structures comprises a high-Q capacitively-loaded conducting-wire loop.
FILED	Wednesday, December 23, 2009
APPL NO	12/646524
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/104
VIEW PATENT	@ USPTO: Full Text PDF

08400024 — Wireless energy transfer across variable distances

US 08400024	Joannopoulos et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts)
ABSTRACT	Described herein are embodiments of transferring electromagnetic energy that includes a first electromagnetic resonator receiving energy from an external power supply, said first resonator having a resonant frequency ω₁, an intrinsic loss rate Γ₁, and a first Q-factor Q₁=ω₁L₁/(R_1ohm+R_1rad), generating an oscillating near field region, a second electromagnetic resonator being positioned at variable distances from said first resonator and not electrically wired to said first resonator, said second resonator having a resonant frequency ω₂, an intrinsic loss rate Γ₂, and a second Q-factor Q₂=ω₂L₂/(R_2ohm+R_2rad). Electromagnetic energy may be transferred from said first resonator to said second resonator over a variable distance D that may be within the near-field region of the first resonator structure, and wherein R_1ohm>R_1rad, and R_2ohm>R_2rad.
FILED	Wednesday, December 30, 2009
APPL NO	12/649973
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/104
VIEW PATENT	@ USPTO: Full Text PDF

08401261 — Imaging facial signs of neuro-physiological responses

US 08401261	Pavlidis
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Ioannis Pavlidis (Houston, Texas)
ASSIGNEE(S)	University of Houston System (Houston, Texas)
INVENTOR(S)	Ioannis Pavlidis (Houston, Texas)
ABSTRACT	The invention provides an integrated framework for detecting peripheral sympathetic responses through imaging. The measurements may be performed on three facial areas of sympathetic importance, that is, periorbital, supraorbital, and maxillary. Because the imaging measurements are thermal in nature and comprise multiple components of variable frequency (i.e., blood flow, sweat gland activation, and breathing), wavelets are used as the image analysis framework. The image analysis may be grounded on GSR signals.
FILED	Thursday, September 25, 2008
APPL NO	12/237889
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Image analysis 382/128
VIEW PATENT	@ USPTO: Full Text PDF

08401264 — Solid modeling based on volumetric scans

US 08401264	Storti et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Duane Storti (Seattle, Washington); Mark Ganter (Edmonds, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Duane Storti (Seattle, Washington); Mark Ganter (Edmonds, Washington)
ABSTRACT	The geometry of an object is inferred from values of the signed distance sampled on a uniform grid to efficiently model objects based on data derived from imaging technology that is now ubiquitous in medical diagnostics. Techniques for automated segmentation convert imaging intensity to a signed distance function (SDF), and a voxel structure imposes a uniform sampling grid. Essential properties of the SDF are used to construct upper and lower bounds on the allowed variation in signed distance in 1, 2, and 3 (or more) dimensions. The bounds are combined to produce interval-valued extensions of the SDF, including a tight global extension and more computationally efficient local bounds that provide useful criteria for root exclusion/isolation, enabling modeling of the objects and other applications.
FILED	Thursday, April 30, 2009
APPL NO	12/433555
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/131
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08401798 — Systems and methods for constructing frequency lookup tables for expression systems

US 08401798	Welch et al.
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Mark Welch (Fremont, California); Claes Gustafsson (Belmont, California)
ASSIGNEE(S)	DNA Twopointo, Inc. (Menlo Park, California)
INVENTOR(S)	Mark Welch (Fremont, California); Claes Gustafsson (Belmont, California)
ABSTRACT	Methods for determining a property that affects expression of polynucleotides are provided. A plurality of polynucleotides each encoding a polypeptide sequence is constructed. A frequency that a sequence element is used in a first polynucleotide is different than in a second polynucleotide. Each polynucleotide is expressed in an expression system to obtain an expression property value thereby constructing a dataset that contains, for each respective polynucleotide, sequence element occurrence in the respective polynucleotide and the measured expression property value of the respective polynucleotide. A model is computed that describes variation in the measured expression property values as a function of a plurality of variables and weights. From the model, a property that affects expression of polynucleotides in the expression system is determined, where the property is an effect that the frequency of occurrence of one or more sequence elements has on the expression property of polynucleotides in the expression system.
FILED	Thursday, July 31, 2008
APPL NO	12/184233
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

08398950 — Condensation polymers having covalently bound carbon nanotubes

US 08398950	Khabashesku
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Valery N. Khabashesku (Houston, Texas)
ASSIGNEE(S)	William Marsh Rice University (Houston, Texas)
INVENTOR(S)	Valery N. Khabashesku (Houston, Texas)
ABSTRACT	The present disclosure describes carbon nanotube materials and condensation polymers having at least one bridge between carbon nanotubes. Carbon nanotube materials comprise a plurality of functionalized single-wall carbon nanotubes linked to at least one other single-wall carbon nanotube by at least one bridge. The at least one bridge comprises at least one amine functionality bonded to the functionalized single-wall carbon nanotubes. The amine functionality may be alkyl or aryl. Carbon nanotube condensation polymers having at least one bridge between single-wall carbon nanotubes are also disclosed. The bridges in the condensation polymers comprise an amine functionality and a condensation agent.
FILED	Tuesday, October 14, 2008
APPL NO	12/250831
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemistry of inorganic compounds 423/447.200
VIEW PATENT	@ USPTO: Full Text PDF

08399649 — Methods of detecting and controlling mucoid Pseudomonas biofilm production

US 08399649	Yu et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Ames Research Center (ARC)
APPLICANT(S)	Hongwei D. Yu (Huntington, West Virginia); Dongru Qiu (Huntington, West Virginia)
ASSIGNEE(S)	Marshall University Research Corporation (Huntington, West Virginia)
INVENTOR(S)	Hongwei D. Yu (Huntington, West Virginia); Dongru Qiu (Huntington, West Virginia)
ABSTRACT	Compositions and methods for detecting and controlling the conversion to mucoidy in Pseudomonas aeruginosa are disclosed. The present invention provides for detecting the switch from nonmucoid to mucoid state of P. aeruginosa by measuring mucE expression or MucE protein levels. The interaction between MucE and AlgW controls the switch to mucoidy in wild type P. aeruginosa. Also disclosed is an alginate biosynthesis heterologous expression system for use in screening candidate substances that inhibit conversion to mucoidy.
FILED	Monday, June 21, 2010
APPL NO	12/819770
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Organic compounds 536/23.700
VIEW PATENT	@ USPTO: Full Text PDF

08401217 — Extreme low frequency acoustic measurement system

US 08401217	Shams et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Qamar A. Shams (Yorktown, Virginia); Allan J. Zuckerwar (Williamsburg, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Qamar A. Shams (Yorktown, Virginia); Allan J. Zuckerwar (Williamsburg, Virginia)
ABSTRACT	The present invention is an extremely low frequency (ELF) microphone and acoustic measurement system capable of infrasound detection in a portable and easily deployable form factor. In one embodiment of the invention, an extremely low frequency electret microphone comprises a membrane, a backplate, and a backchamber. The backchamber is sealed to allow substantially no air exchange between the backchamber and outside the microphone. Compliance of the membrane may be less than ambient air compliance. The backplate may define a plurality of holes and a slot may be defined between an outer diameter of the backplate and an inner wall of the microphone. The locations and sizes of the holes, the size of the slot, and the volume of the backchamber may be selected such that membrane motion is substantially critically damped.
FILED	Friday, July 20, 2007
APPL NO	11/780500
ART UNIT	2656 — Digital Audio Data Processing
CURRENT CPC	Electrical audio signal processing systems and devices 381/353
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08401700 — Actuator and electronics packaging for extrinsic humanoid hand

US 08401700	Ihrke et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Chris A. Ihrke (Hartland, Michigan); Lyndon Bridgwater (Houston, Texas); Myron A. Diftler (Houston, Texas); David M. Reich (Huntsville, Alabama); Scott R. Askew (Houston, Texas)
ASSIGNEE(S)	GM Global Technology Operations LLC (Detroit, Michigan); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Chris A. Ihrke (Hartland, Michigan); Lyndon Bridgwater (Houston, Texas); Myron A. Diftler (Houston, Texas); David M. Reich (Huntsville, Alabama); Scott R. Askew (Houston, Texas)
ABSTRACT	The lower arm assembly for a humanoid robot includes an arm support having a first side and a second side, a plurality of wrist actuators mounted to the first side of the arm support, a plurality of finger actuators mounted to the second side of the arm support and a plurality of electronics also located on the first side of the arm support.
FILED	Tuesday, September 22, 2009
APPL NO	12/564124
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Generic control systems or specific applications 7/245
VIEW PATENT	@ USPTO: Full Text PDF

08401793 — High resolution wind measurements for offshore wind energy development

US 08401793	Nghiem et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Son Van Nghiem (Arcadia, California); Gregory Neumann (La Verne, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Son Van Nghiem (Arcadia, California); Gregory Neumann (La Verne, California)
ABSTRACT	A method, apparatus, system, article of manufacture, and computer readable storage medium provide the ability to measure wind. Data at a first resolution (i.e., low resolution data) is collected by a satellite scatterometer. Thin slices of the data are determined. A collocation of the data slices are determined at each grid cell center to obtain ensembles of collocated data slices. Each ensemble of collocated data slices is decomposed into a mean part and a fluctuating part. The data is reconstructed at a second resolution from the mean part and a residue of the fluctuating part. A wind measurement is determined from the data at the second resolution using a wind model function. A description of the wind measurement is output.
FILED	Thursday, April 29, 2010
APPL NO	12/770443
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/3
VIEW PATENT	@ USPTO: Full Text PDF

08401820 — In situ health monitoring of piezoelectric sensors

US 08401820	Jensen et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Scott L. Jensen (Carriere, Mississippi); George J. Drouant (Mandeville, Louisiana)
ASSIGNEE(S)	United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Scott L. Jensen (Carriere, Mississippi); George J. Drouant (Mandeville, Louisiana)
ABSTRACT	An in situ health monitoring apparatus may include an exciter circuit that applies a pulse to a piezoelectric transducer and a data processing system that determines the piezoelectric transducer's dynamic response to the first pulse. The dynamic response can be used to evaluate the operating range, health, and as-mounted resonance frequency of the transducer, as well as the strength of a coupling between the transducer and a structure and the health of the structure.
FILED	Thursday, September 24, 2009
APPL NO	12/566111
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/182
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

08400355 — Passive photonic dense wavelength-division multiplexing true-time-delay system

US 08400355	Gaeta
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Small Business Administration (SBA) Small Business Technology Transfer (STTR)
APPLICANT(S)	Celestino John Gaeta (Carlsbad, California)
ASSIGNEE(S)	Ipitek, Inc. (Carlsbad, California)
INVENTOR(S)	Celestino John Gaeta (Carlsbad, California)
ABSTRACT	A photonic true time delay system for steering one or more radio frequency beams from an electronically scanned array antenna incorporates passive optical true time delay modules for the entire array based upon dense-wavelength-division multiplexed encoding of optical time delays. In addition, electronic selection of time delays allows for elimination of optical filter tuning and optical switching, and can function in either or both transmit and receive modes of the antenna array.
FILED	Friday, April 03, 2009
APPL NO	12/418272
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Communications: Directive radio wave systems and devices 342/377
VIEW PATENT	@ USPTO: Full Text PDF

08401798 — Systems and methods for constructing frequency lookup tables for expression systems

US 08401798	Welch et al.
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Mark Welch (Fremont, California); Claes Gustafsson (Belmont, California)
ASSIGNEE(S)	DNA Twopointo, Inc. (Menlo Park, California)
INVENTOR(S)	Mark Welch (Fremont, California); Claes Gustafsson (Belmont, California)
ABSTRACT	Methods for determining a property that affects expression of polynucleotides are provided. A plurality of polynucleotides each encoding a polypeptide sequence is constructed. A frequency that a sequence element is used in a first polynucleotide is different than in a second polynucleotide. Each polynucleotide is expressed in an expression system to obtain an expression property value thereby constructing a dataset that contains, for each respective polynucleotide, sequence element occurrence in the respective polynucleotide and the measured expression property value of the respective polynucleotide. A model is computed that describes variation in the measured expression property values as a function of a plurality of variables and weights. From the model, a property that affects expression of polynucleotides in the expression system is determined, where the property is an effect that the frequency of occurrence of one or more sequence elements has on the expression property of polynucleotides in the expression system.
FILED	Thursday, July 31, 2008
APPL NO	12/184233
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

08401799 — Antibody design using anti-lipid antibody crystal structures

US 08401799	Sabbadini et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Roger A. Sabbadini (Lakeside, California); Tom Huxford (San Diego, California); Jonathan Michael Wojciak (Encinitas, California)
ASSIGNEE(S)	Lpath, Inc. (San Diego, California)
INVENTOR(S)	Roger A. Sabbadini (Lakeside, California); Tom Huxford (San Diego, California); Jonathan Michael Wojciak (Encinitas, California)
ABSTRACT	Methods for designing optimized antibodies, including optimized humainized or human antibodies, to target bioactive lipids are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Antibodies produced by these methods are also provided, as are methods for using them.
FILED	Friday, June 04, 2010
APPL NO	12/794668
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

Department of Agriculture (USDA)

08398842 — Electrochemical process for the preparation of nitrogen fertilizers

US 08398842	Aulich et al.
FUNDED BY	Department of Energy (DOE) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Ted R. Aulich (Grand Forks, North Dakota); Edwin S. Olson (Grand Forks, North Dakota); Junhua Jiang (Grand Forks, North Dakota)
ASSIGNEE(S)	Energy and Environmental Research Center Foundation (Grand Forks, California)
INVENTOR(S)	Ted R. Aulich (Grand Forks, North Dakota); Edwin S. Olson (Grand Forks, North Dakota); Junhua Jiang (Grand Forks, North Dakota)
ABSTRACT	The present invention provides methods and apparatus for the preparation of nitrogen fertilizers including ammonium nitrate, urea, urea-ammonium nitrate, and/or ammonia utilizing a source of carbon, a source of nitrogen, and/or a source of hydrogen. Implementing an electrolyte serving as ionic charge carrier, (1) ammonium nitrate is produced via the reduction of a nitrogen source at the cathode and the oxidation of a nitrogen source at the anode; (2) urea or its isomers are produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source; (3) ammonia is produced via the reduction of nitrogen source at the cathode and the oxidation of a hydrogen source at the anode; and (4) urea-ammonium nitrate is produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source, and anodic oxidation of a nitrogen source. The electrolyte can be solid.
FILED	Thursday, March 15, 2012
APPL NO	13/420979
ART UNIT	1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/551
VIEW PATENT	@ USPTO: Full Text PDF

PP023489 — Miscanthus plant named ‘MSU-MFL1’

US PP23489	Baldwin
FUNDED BY	Department of Agriculture (USDA) Agricultural Research Service (ARS) Cooperative State Research, Education, and Extension Service (CSREES)
APPLICANT(S)	Brian S. Baldwin (Starkville, Mississippi)
ASSIGNEE(S)	Mississippi State University (Mississippi State, Mississippi)
INVENTOR(S)	Brian S. Baldwin (Starkville, Mississippi)
ABSTRACT	Miscanthus plant ‘MSU MFL1’ is a new and distinct variety of giant Miscanthus, characterized by vigorous growth and its usefulness as an effective biomass grass that yields, on average, two to three times more tons per acre than switchgrass, the predominant biomass grass.
FILED	Monday, March 07, 2011
APPL NO	12/932823
ART UNIT	1661 — Plants
CURRENT CPC	Plants PLT/384
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

08397537 — Method for local reversible glass swelling

US 08397537	Grzybowski et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	Richard R Grzybowski (Corning, New York); Alexander Mikhailovich Streltsov (Corning, New York); James Scott Sutherland (Corning, New York)
ASSIGNEE(S)	Corning Incorporated (Corning, New York)
INVENTOR(S)	Richard R Grzybowski (Corning, New York); Alexander Mikhailovich Streltsov (Corning, New York); James Scott Sutherland (Corning, New York)
ABSTRACT	A method of forming, on the surface of a glass material, a raised feature having a height within a target range, comprising (1) providing a glass material having a surface, (2) providing the glass material locally, at a location at or below the surface, with an amount of energy causing local expansion of the glass material so as to raise a feature on the surface at the location, (3) detecting the height of the raised feature or the height over time of the raised feature, (4) (a) if the height is below or approaching a value below the target range, providing the glass material at the location with energy in a greater amount, or (b) if the height is above or approaching a value above the target range, providing the glass material at the location with energy in a lesser amount, and (5) repeating steps (3) and (4) as needed to bring the height within the target range. Methods and devices for automating this process are also disclosed.
FILED	Monday, July 16, 2007
APPL NO	12/669381
ART UNIT	1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Glass manufacturing 065/106
VIEW PATENT	@ USPTO: Full Text PDF

08399292 — Fabricating a semiconductor chip with backside optical vias

US 08399292	Doany et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	Fuad Elias Doany (Katonah, New York); Christopher Vincent Jahnes (Saddle River, New Jersey); Clint Lee Schow (Ossining, New York); Mehmet Soyuer (Stamford, Connecticut); Alexander V. Rylyakov (Mount Kisco, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Fuad Elias Doany (Katonah, New York); Christopher Vincent Jahnes (Saddle River, New Jersey); Clint Lee Schow (Ossining, New York); Mehmet Soyuer (Stamford, Connecticut); Alexander V. Rylyakov (Mount Kisco, New York)
ABSTRACT	Fabricating a semiconductor chip with backside optical vias is provided. A silicon wafer is received for processing. The silicon wafer includes an optically transparent oxide layer on a frontside of the silicon wafer. A complementary metal-oxide-semiconductor layer is formed on top of the optically transparent oxide layer. A backside of the silicon wafer is etched to form optical vias in a silicon substrate using the optically transparent oxide layer as an etch-stop.
FILED	Wednesday, June 30, 2010
APPL NO	12/827825
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/106
VIEW PATENT	@ USPTO: Full Text PDF

Department of Commerce (DOC)

08398922 — Highly sensitive oxygen sensor for cell culture

US 08398922	Forry et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Samuel P. Forry (Rockville, Maryland); Peter C. Thomas (Germantown, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia)
INVENTOR(S)	Samuel P. Forry (Rockville, Maryland); Peter C. Thomas (Germantown, Maryland)
ABSTRACT	An oxygen sensor comprising an oxygen sensing compound and configured to substantially mitigate leaching of the oxygen sensing compound from the oxygen sensor to an outer surface thereof is provided. The oxygen sensor may comprise one or more layers. A first portion of the oxygen sensor is configured to be permeable to gas and comprises an oxygen sensing material. A second portion is disposed with or on the first portion and is configured to be permeable to gas and substantially impermeable to the oxygen sensing material.
FILED	Friday, October 08, 2010
APPL NO	12/900587
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/83
VIEW PATENT	@ USPTO: Full Text PDF

Department of Homeland Security (DHS)

08401270 — Examination of a region using dual-energy radiation

US 08401270	Eilbert et al.
FUNDED BY	Department of Homeland Security (DHS) Countering Weapons of Mass Destruction Office (CWMD) Domestic Nuclear Detection Office (DNDO) Science and Technology Directorate (DHS-ST)
APPLICANT(S)	Richard F. Eilbert (Lincoln, Massachusetts); David Perticone (Winchester, Massachusetts); Shuanghe Shi (Southborough, Massachusetts); Jeff Stillson (Merrimack, New Hampshire)
ASSIGNEE(S)	L-3 Communications Security and Detection Systems, Inc. (Woburn, Massachusetts)
INVENTOR(S)	Richard F. Eilbert (Lincoln, Massachusetts); David Perticone (Winchester, Massachusetts); Shuanghe Shi (Southborough, Massachusetts); Jeff Stillson (Merrimack, New Hampshire)
ABSTRACT	A first image including a projection of a portion is generated based on data representing attenuation of higher-energy radiation having a peak energy of at least 1 MeV that passes through a portion of an inspection volume. A second image including a projection of the portion is generated based on data representing attenuation of lower-energy radiation passing through the portion of the inspection volume. A dual-pixel image is created from the first image and the second image. A region of interest is selected from the dual-pixel image. A first basis function that is derived from an attenuation characteristic associated with the region of interest is selected. The region of interest is represented in terms of an amplitude associated with the first basis function and an amplitude associated with the second basis function.
FILED	Monday, June 15, 2009
APPL NO	12/484709
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/141
VIEW PATENT	@ USPTO: Full Text PDF

Department of Justice (DOJ)

08402267 — Security enhanced network device and method for secure operation of same

US 08402267	Graham et al.
FUNDED BY	Department of Justice (DOJ) Office of Justice Programs (OJP) National Institute of Justice (NIJ)
APPLICANT(S)	James H. Graham (Sellersburg, Indiana); Jeffrey Hieb (Shelbyville, Kentucky)
ASSIGNEE(S)	University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S)	James H. Graham (Sellersburg, Indiana); Jeffrey Hieb (Shelbyville, Kentucky)
ABSTRACT	A security enhanced network device includes a processor, a memory, and a communication controller operably connected to form a processing device. A microkernel provides a partitioning between a communication address space, a security enforcement address space, and a protected operations address space. The communication address space contains communications threads for interacting with a network. The protected operations address space contains protected operations threads for performing protected operations. The security enforcement address space contains security threads for providing secure isolation of the protected operations address space from the communication address space. A method of secure operation of the network device includes: partitioning the network device into the communication address space, the security enforcement address space, and the protected operations address space; interacting with the network; providing secure isolation of the protected operations address space from the communication address space; and performing protected operations.
FILED	Wednesday, March 17, 2010
APPL NO	12/726105
ART UNIT	2438 — Cryptography and Security
CURRENT CPC	Electrical computers and digital processing systems: Support 713/164
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

08399518 — Administration of 3,5-diiodothyropropionic acid for stimulating weight loss, and/or lowering triglyceride levels, and/or treatment of metabolic syndrome

US 08399518	Morkin et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Eugene Morkin (Tucson, Arizona); Louis R. Bucalo (Miami, Florida); Steven Goldman (Tucson, Arizona)
ASSIGNEE(S)	University of Arizona Office of Technology Transfer (Tucson, Arizona); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Eugene Morkin (Tucson, Arizona); Louis R. Bucalo (Miami, Florida); Steven Goldman (Tucson, Arizona)
ABSTRACT	Methods and compositions are disclosed for stimulating weight loss and/or lowering triglyceride levels in an individual mammal in need thereof. In an exemplary method, a pharmaceutical composition comprising a therapeutically effective amount of DITPA, and optionally one or more lipid-reducing agents, is administered to an individual mammal to stimulate weight loss, and/or reduce levels of triglyceride and/or lipoprotein in the mammal.
FILED	Wednesday, February 27, 2008
APPL NO	12/596818
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/568
VIEW PATENT	@ USPTO: Full Text PDF

Environmental Protection Agency (EPA)

08397848 — Hydraulic-electric regenerative energy storage system for plug-in hybrid motor vehicles

US 08397848	Read
FUNDED BY	Environmental Protection Agency (EPA)
APPLICANT(S)	David H. Read (Dexter, Michigan)
ASSIGNEE(S)	The United States of America, as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia)
INVENTOR(S)	David H. Read (Dexter, Michigan)
ABSTRACT	A hydraulic energy storage system (comprising a hydraulic pump/motor, a high pressure hydraulic accumulator, a low pressure hydraulic accumulator/reservoir, and interconnecting hydraulic lines) is incorporated into a EV, HEV, or PHEV to provide hydraulic regenerative braking and propulsive assistance for the vehicle. Implementation of the low cost and long-lasting hydraulic energy storage system in the vehicle, together with the electric energy storage system (comprising a motor/generator and battery pack) of the vehicle, allows significantly reduced demands and higher operating efficiencies for the battery pack, thereby facilitating a more cost-effective, efficient and/or durable overall energy storage system for the vehicle.
FILED	Monday, August 20, 2012
APPL NO	13/589445
ART UNIT	3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Motor vehicles 180/65.210
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

08399684 — Sulfonamide-based organocatalysts and method for their use

US 08399684	Carter et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) U.S. State Government State of Oregon
APPLICANT(S)	Rich Garrett Carter (Corvallis, Oregon); Hua Yang (Corvallis, Oregon)
ASSIGNEE(S)	State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S)	Rich Garrett Carter (Corvallis, Oregon); Hua Yang (Corvallis, Oregon)
ABSTRACT	Organocatalysts, particularly proline sulfonamide organocatalysts, having a first general formula as follows are disclosed. Embodiments of a method for using these organocatalysts also are disclosed. The method comprises providing a disclosed organocatalyst, and performing a reaction, often an enantioselective or diastereoselective reaction, using the organocatalyst. Solely by way of example, disclosed catalysts can be used to perform aldol reactions, conjugate additions, Michael additions, Robinson annulations, Mannich reactions, α-aminooxylations, α-hydroxyaminations, α-aminations and alkylation reactions. Certain of such reactions are intramolecular cyclizations used to form cyclic compounds, such as 5-or 6-membered rings, having one or more chiral centers Disclosed organocatalysts generally are much more soluble in typical solvents used for organic synthesis than are known compounds. Moreover, the reaction yield is generally quite good with disclosed compounds, as is their enantioselective and diastereoselective effectiveness.
FILED	Wednesday, March 17, 2010
APPL NO	12/726212
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Organic compounds 548/495
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

08401976 — Method and system for providing a barcode image over a network

US 08401976	Dixon et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	Kyle M. Dixon (Germantown, Tennessee); Stephen M. Dearing (Cordova, Tennessee)
ASSIGNEE(S)	The United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	Kyle M. Dixon (Germantown, Tennessee); Stephen M. Dearing (Cordova, Tennessee)
ABSTRACT	Methods and systems consistent with the present invention provide a barcode image. A client is operable to create a request for a barcode image and send the request to a server. The request comprises data to be converted to a barcode. The server is operable to receive the request from the client via a network, generate a barcode image from the data, and encode the barcode image. Thereafter, the server provides the encoded image to the client.
FILED	Wednesday, December 27, 2006
APPL NO	11/645531
ART UNIT	3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Data processing: Financial, business practice, management, or cost/price determination 75/410
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

08398182 — Lightweight wear ring

US 08398182	Simula et al.
FUNDED BY
APPLICANT(S)	Glen Raymond Simula (Hancock, Michigan); Steven John Tarnowski (Calumet, Michigan)
ASSIGNEE(S)	GSE Technologies, LLC (Houghton, Michigan)
INVENTOR(S)	Glen Raymond Simula (Hancock, Michigan); Steven John Tarnowski (Calumet, Michigan)
ABSTRACT	A segmented wear ring 40 for a tracked vehicle 10 road wheel 22 that cooperates with a track guide 32. The segmented wear ring 40 has at least two wear ring segments 42, and each of the wear ring segments 42 have a wear surface 50. The wear ring segments 42 are attached to a tracked vehicle wheel 22 such that the wear surfaces of each of the wear ring segments 42 form a substantially uninterrupted wear surface 50 designed to cooperate with a track guide 32.
FILED	Monday, June 07, 2010
APPL NO	12/795075
ART UNIT	3617 — Static Structures, Supports and Furniture
CURRENT CPC	Wheel substitutes for land vehicles 35/194
VIEW PATENT	@ USPTO: Full Text PDF

08400391 — Method and system for improving dimming performance in a field sequential color display device

US 08400391	Schmidt et al.
FUNDED BY
APPLICANT(S)	John Schmidt (Phoenix, Arizona); Kalluri R. Sarma (Mesa, Arizona); Dennis M. Davey (Phoenix, Arizona)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	John Schmidt (Phoenix, Arizona); Kalluri R. Sarma (Mesa, Arizona); Dennis M. Davey (Phoenix, Arizona)
ABSTRACT	Methods and systems for displaying an image on a display device having first and second light sources are provided. A video signal is provided to the display device. The video signal includes first and second video frames. Each video frame includes first and second sub-frames corresponding to the respective first and second light sources. The first light source is operated for a first duration during the first sub-frame of the first video frame. The first light source is operated for a second duration during the first sub-frame of the second video frame. The second duration is different from the first duration.
FILED	Thursday, January 10, 2008
APPL NO	11/972199
ART UNIT	2691 — Selective Visual Display Systems
CURRENT CPC	Computer graphics processing and selective visual display systems 345/102
VIEW PATENT	@ USPTO: Full Text PDF

08401626 — System and method for assessing sleep quality

US 08401626	Mietus et al.
FUNDED BY
APPLICANT(S)	Joseph E. Mietus (Cambridge, Massachusetts); Chung-Kang Peng (Sharon, Massachusetts); Robert Joseph Thomas (Newton, Massachusetts); Ary L. Goldberger (Newton Centre, Massachusetts)
ASSIGNEE(S)	Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S)	Joseph E. Mietus (Cambridge, Massachusetts); Chung-Kang Peng (Sharon, Massachusetts); Robert Joseph Thomas (Newton, Massachusetts); Ary L. Goldberger (Newton Centre, Massachusetts)
ABSTRACT	An assessment of sleep quality and sleep disordered breathing is determined from cardiopulmonary coupling between two physiological data series. An R-R interval series is derived from an electrocardiogram (ECG) signal. The normal beats from the R-R interval series are extracted to produce a normal-to-normal interval series. The amplitude variations in the QRS complex are used to extract a surrogate respiration signal (i.e., ECG-derived respiration) associated with the NN interval series. The two series are corrected to remove outliers, and resampled. The cross-spectral power and coherence of the two resampled signals are calculated over a plurality of coherence windows. For each coherence window, the product of the coherence and cross-spectral power is used to calculate coherent cross-power. Using the appropriate thresholds for the coherent cross-power, the proportion of sleep spent in CAP, non-CAP, and wake and/or REM are determined. Coherent cross-power can be applied to differentiate obstructive from non-obstructive disease, and admixtures of the same.
FILED	Wednesday, September 30, 2009
APPL NO	12/570163
ART UNIT	3766 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Surgery 6/513
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, March 19, 2013.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130319.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital