FedInvent™ Patents
Patent Details for Tuesday, April 16, 2013
This page was updated on Monday, March 27, 2023 at 03:46 AM GMT
Department of Health and Human Services (HHS)
| US 08418535 | Manalis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Scott Manalis (Cambridge, Massachusetts); Thomas Burg (Goettingen, Germany); Philip Dextras (Tokyo, Japan) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Scott Manalis (Cambridge, Massachusetts); Thomas Burg (Goettingen, Germany); Philip Dextras (Tokyo, Japan) |
| ABSTRACT | Measurements of the mass and surface charge of microparticles are employed in the characterization of many types of colloidal dispersions. The suspended microchannel resonator (SMR) is capable of measuring individual particle masses with femtogram resolution. The high sensitivity of the SMR resonance frequency to changes in particle position in the SMR channel is employed to determine the electrophoretic mobility of discrete particles in an applied electric field. When an oscillating electric field is applied to the suspended microchannel, the transient resonance frequency shift corresponding to a particle transit can be analyzed to extract both the buoyant mass and electrophoretic mobility of each particle. These parameters, together with the mean particle density, can be used to compute the size, absolute mass, and surface charge of discrete particles. |
| FILED | Tuesday, May 04, 2010 |
| APPL NO | 12/799922 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/64.530 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419643 | Sarvazyan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Armen P. Sarvazyan (Lambertville, New Jersey); Alexej Tatarinov (Riga, Latvia); Vladimir Egorov (Princeton, New Jersey) |
| ASSIGNEE(S) | Artann Laboratories Inc. (Trenton, New Jersey) |
| INVENTOR(S) | Armen P. Sarvazyan (Lambertville, New Jersey); Alexej Tatarinov (Riga, Latvia); Vladimir Egorov (Princeton, New Jersey) |
| ABSTRACT | Methods and apparatus are disclosed for non-invasive bone evaluation based on a broadband ultrasonic transducer emitting a train of ultrasonic wave packets of multiple carrier frequencies ranging from about 50 kHz to about 2 MHz. Receiving broadband ultrasonic transducer accepts broadband ultrasonic signal propagated through the bone. Computer processor provides for data analysis and feature extraction allowing diagnostic evaluation of the bone, including comparing the features of the received signal to a database of known bone conditions. |
| FILED | Thursday, September 21, 2006 |
| APPL NO | 11/533871 |
| ART UNIT | 3737 — Semiconductors/Memory |
| CURRENT CPC | Surgery 6/449 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419659 | Egorov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vladmir Egorov (Princeton, New Jersey); Heather van Raalte (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey) |
| ASSIGNEE(S) | Artann Laboratories (Trenton, New Jersey) |
| INVENTOR(S) | Vladmir Egorov (Princeton, New Jersey); Heather van Raalte (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey) |
| ABSTRACT | Methods for assessment of pelvic floor conditions based on tactile imaging are described. The vaginal wall is deformed before and after an interventional procedure using a transvaginal probe equipped with tactile pressure sensors and a motion tracking sensor. The vaginal wall coordinates and pressure patterns are obtained during the examination and used to build 3-D tactile image of the vagina and to calculate elasticity modulus profiles and spacing profiles along selected lines inside 3-D tactile image. The “before” and “after” profile values at specified locations are then compared to each other and to thresholds or profiles for normal conditions of vagina and its support structures. Methods of the invention may be used in estimating an improvement after an interventional procedure such as pelvic tissue regeneration, muscle repair or implantation of a supporting structure. |
| FILED | Wednesday, April 04, 2012 |
| APPL NO | 13/439165 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/591 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420071 | Whitley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Richard J. Whitley (Birmingham, Alabama); James MacDowell Markert (Birmingham, Alabama); George Yancey Gillespie (Birmingham, Alabama); Jacqueline Nuss Parker (Birmingham, Alabama) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Richard J. Whitley (Birmingham, Alabama); James MacDowell Markert (Birmingham, Alabama); George Yancey Gillespie (Birmingham, Alabama); Jacqueline Nuss Parker (Birmingham, Alabama) |
| ABSTRACT | An anti-cancer pharmaceutical composition includes a herpes simplex virus (HSV) vector into which a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD has been inserted. A method of treatment of a patient suffering from cancer includes administering to the patient the anti-tumor pharmaceutical composition including a HSV vector having a nucleic acid sequence encoding for an anti-cancer agent selected from interleukin-12, GM-CSF, and CD inserted therein. |
| FILED | Friday, September 19, 2008 |
| APPL NO | 12/234246 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420080 | Bhattacharya et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jahar Bhattacharya (New York City, New York); Sadiqa K. Quadri (Teaneck, New Jersey); Shonit Das (Bronx, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jahar Bhattacharya (New York City, New York); Sadiqa K. Quadri (Teaneck, New Jersey); Shonit Das (Bronx, New York) |
| ABSTRACT | We have discovered that the activated phosphorylated form of focal adhesion kinase (hereafter “FAKp”) strengthens the microvascular endothelial cell (EC) junctions that form a barrier in pulmonary endothelia, and the increased barrier helps to prevent acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Thus certain embodiments of the invention are directed to prevention and treatment of ALI and ARDS by administering a therapeutically effective amount of FAKp to subjects at risk of developing or diagnosed as having either ALI or ARDS. |
| FILED | Wednesday, October 01, 2008 |
| APPL NO | 12/681058 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.650 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420096 | Hawiger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jack J. Hawiger (Nashville, Tennessee); Daewoong Jo (Gwangju, South Korea) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Jack J. Hawiger (Nashville, Tennessee); Daewoong Jo (Gwangju, South Korea) |
| ABSTRACT | Disclosed are compositions and methods related to cell-penetrating suppressor of cytokine signaling (SOCS) proteins that inhibit cytokine-induced signaling. |
| FILED | Friday, March 04, 2005 |
| APPL NO | 10/589726 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420099 | Berger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Edward A. Berger (Rockville, Maryland); Christie M. Del Castillo (San Francisco, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Edward A. Berger (Rockville, Maryland); Christie M. Del Castillo (San Francisco, California) |
| ABSTRACT | This invention relates to bispecific fusion proteins effective in viral neutralization. More specifically, such proteins have two different binding domains, an inducing-binding domain and an induced-binding domain, functionally linked by a peptide linker. Such proteins, nucleic acid molecules encoding them, and their production and use in preventing or treating viral infections are provided. One prototypical bispecific fusion protein is sCD4-SCFv(17b), in which a soluble CD4 fragment (containing domains D1 and D2) is fused to a single chain Fv portion of antibody 17b via a linker. |
| FILED | Wednesday, September 27, 2006 |
| APPL NO | 11/535957 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/192.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420107 | Beall et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bernard W. Beall (Doraville, Georgia); George M. Carlone (Stone Mountain, Georgia); Jacquelyn S. Sampson (College Park, Georgia); Edwin W. Ades (Atlanta, Georgia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Bernard W. Beall (Doraville, Georgia); George M. Carlone (Stone Mountain, Georgia); Jacquelyn S. Sampson (College Park, Georgia); Edwin W. Ades (Atlanta, Georgia) |
| ABSTRACT | This invention, in one aspect, relates to synthetic immunoreactive peptides. These peptides are approximately 20-25 amino acids in length which are portions of the N termini of the M proteins of the most prevalent United States (U.S.) Group A Streptococcus (GAS) serotypes. At least some of the synthetic peptides can be recognized by M type-specific antibodies and are capable of eliciting functional opsonic antibodies and/or anti-attachment antibodies without eliciting tissue cross-reactive antibodies. In another aspect, it relates to compositions or vaccines comprising these synthetic serotype-specific peptides, including polypeptides and proteins. The invention may also be isolated antibodies which are raised in response to the peptides, compositions or vaccines. The invention further relates to kits for using the peptides, compositions, or antibodies. In still further aspects, the invention also relates to methods for using the peptides, compositions, vaccines, or antibodies and methods for tailoring vaccines. |
| FILED | Thursday, March 22, 2012 |
| APPL NO | 13/427477 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/244.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420118 | Awasthi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vibhudutta Awasthi (Edmond, Oklahoma); Pallavi Lagisetty (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Vibhudutta Awasthi (Edmond, Oklahoma); Pallavi Lagisetty (Oklahoma City, Oklahoma) |
| ABSTRACT | Anionic non-phospholipids, as well as lipid nanostructures formed therefrom, are disclosed herein. Also disclosed are methods of producing and using same. |
| FILED | Thursday, September 10, 2009 |
| APPL NO | 12/556906 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420126 | Tseng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Wei Li (Songgang Town, China PRC) |
| ASSIGNEE(S) | Tissue Tech, Inc. (Miami, Florida) |
| INVENTOR(S) | Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Wei Li (Songgang Town, China PRC) |
| ABSTRACT | Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases. |
| FILED | Monday, April 23, 2012 |
| APPL NO | 13/453840 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/583 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420155 | Nie et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shuming Nie (Atlanta, Georgia); Robert E. Bailey (Sacramento, California) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Shuming Nie (Atlanta, Georgia); Robert E. Bailey (Sacramento, California) |
| ABSTRACT | An alloyed semiconductor quantum dot comprising an alloy of at least two semiconductors, wherein the quantum dot has a homogeneous composition and is characterized by a band gap energy that is non-linearly related to the molar ratio of the at least two semiconductors; a series of alloyed semiconductor quantum dots related thereto; a concentration-gradient quantum dot comprising an alloy of a first semiconductor and a second semiconductor, wherein the concentration of the first semiconductor gradually increases from the core of the quantum dot to the surface of the quantum dot and the concentration of the second semiconductor gradually decreases from the core of the quantum dot to the surface of the quantum dot; a series of concentration-gradient quantum dots related thereto; in vitro and in vivo methods of use; and methods of producing the alloyed semiconductor and concentration-gradient quantum dots and the series of quantum dots related thereto. |
| FILED | Thursday, June 09, 2011 |
| APPL NO | 13/157099 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Coating processes 427/10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420306 | Doxsey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Stephen J. Doxsey (Princeton, Massachusetts); Chun-Ting Chen (Worcester, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Stephen J. Doxsey (Princeton, Massachusetts); Chun-Ting Chen (Worcester, Massachusetts) |
| ABSTRACT | This application relates to a newly identified animal cell structure, the midbody scar. This structure is a remnant of the midbody that is retained by one daughter cell following cytokinesis and persists through multiple subsequent cell cycles. The midbody scar can be useful as a marker of dividing cells or of a cell's replicative age. |
| FILED | Monday, March 22, 2010 |
| APPL NO | 12/728627 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420307 | Ostermeier et al. |
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| FUNDED BY |
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| APPLICANT(S) | G. Charles Ostermeier (Ranson, West Virginia); Jane S. Farley (Ellsworth, Maine); Robert Taft (Southwest Harbor, Maine); Michael V. Wiles (Mount Desert, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | G. Charles Ostermeier (Ranson, West Virginia); Jane S. Farley (Ellsworth, Maine); Robert Taft (Southwest Harbor, Maine); Michael V. Wiles (Mount Desert, Maine) |
| ABSTRACT | Described herein is a composition that comprises a cryoprotectant; a membrane protectant that stabilizes or assists in stabilization of membranes of sperm; and a free radical scavenger (e.g., a reducing agent, an antioxidant). |
| FILED | Tuesday, June 21, 2011 |
| APPL NO | 13/165265 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420318 | Mathies et al. |
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| FUNDED BY |
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| APPLICANT(S) | Richard A. Mathies (San Francisco, California); Robert Blazej (San Francisco, California); Chung Liu (Albany, California); Palani Kumaresan (Los Angeles, California); Stephanie H. I. Yeung (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard A. Mathies (San Francisco, California); Robert Blazej (San Francisco, California); Chung Liu (Albany, California); Palani Kumaresan (Los Angeles, California); Stephanie H. I. Yeung (Berkeley, California) |
| ABSTRACT | Methods and apparatus for genome analysis are provided. A microfabricated structure including a microfluidic distribution channel is configured to distribute microreactor elements having copies of a sequencing template into a plurality of microfabricated thermal cycling chambers. A microreactor element may include a microcarrier element carrying the multiple copies of the sequencing template. The microcarrier element may comprise a microsphere. An autovalve at an exit port of a thermal cycling chamber, an optical scanner, or a timing arrangement may be used to ensure that only one microsphere will flow into one thermal cycling chamber wherein thermal cycling extension fragments are produced. The extension products are captured, purified, and concentrated in an integrated oligonucleotide gel capture chamber. A microfabricated component separation apparatus is used to analyze the purified extension fragments. The microfabricated structure may be used in a process for performing sequencing and other genetic analysis of DNA or RNA. |
| FILED | Monday, February 13, 2012 |
| APPL NO | 13/372376 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420325 | Loeb et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence A. Loeb (Bellevue, Washington); Leroy Hood (Seattle, Washington); Motoshi Suzuki (Nogoya, Japan) |
| ASSIGNEE(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Lawrence A. Loeb (Bellevue, Washington); Leroy Hood (Seattle, Washington); Motoshi Suzuki (Nogoya, Japan) |
| ABSTRACT | The present invention provides a method for identifying a thermostable polymerase having altered fidelity. The method consists of generating a random population of polymerase mutants by mutating at least one amino acid residue of a thermostable polymerase and screening the population for one or more active polymerase mutants by genetic selection. For example, the invention provides a method for identifying a thermostable polymerase having altered fidelity by mutating at least one amino acid residue in an active site O-helix of a thermostable polymerase. The invention also provides thermostable polymerases and nucleic acids encoding thermostable polymerases having altered fidelity, for example, high fidelity polymerases and low fidelity polymerases. The invention additionally provides a method for identifying one or more mutations in a gene by amplifying the gene with a high fidelity polymerase. The invention further provides a method for accurately copying repetitive nucleotide sequences using a high fidelity polymerase mutant. The invention also provides a method for diagnosing a genetic disease using a high fidelity polymerase mutant. The invention further provides a method for randomly mutagenizing a gene by amplifying the gene using a low fidelity polymerase mutant. |
| FILED | Thursday, November 04, 2010 |
| APPL NO | 12/939798 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420327 | Ellis et al. |
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| FUNDED BY |
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| APPLICANT(S) | April L. Ellis (Pinson, Alabama); Yiming Ye (Duluth, Georgia); Angela Holder (Mableton, Georgia); Yun Huang (Decatur, Georgia); Michael Kirberger (Hampton, Georgia); Jenny Jie Yang (Atlanta, Georgia); Jin Zou (Lilburn, Georgia); Wei Yang (Changchun, China PRC) |
| ASSIGNEE(S) | Georgia State University Research Foundation (Atlanta, Georgia) |
| INVENTOR(S) | April L. Ellis (Pinson, Alabama); Yiming Ye (Duluth, Georgia); Angela Holder (Mableton, Georgia); Yun Huang (Decatur, Georgia); Michael Kirberger (Hampton, Georgia); Jenny Jie Yang (Atlanta, Georgia); Jin Zou (Lilburn, Georgia); Wei Yang (Changchun, China PRC) |
| ABSTRACT | Embodiments of the present disclosure provide for analyte sensors, methods for producing and using the analyte sensors, methods of detecting and/or measuring analyte activity, methods for characterizing analyte cellular activity, methods of detecting pH change in a system, method of controlling the concentration of an analyte in a system, fusion proteins, polynucleotides, and vectors corresponding to the analyte sensors, kits, and the like. |
| FILED | Friday, December 14, 2007 |
| APPL NO | 12/448101 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420330 | Lipes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Myra A. Lipes (Brookline, Massachusetts); Lizbeth Cornivelli (Medford, Massachusetts) |
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| INVENTOR(S) | Myra A. Lipes (Brookline, Massachusetts); Lizbeth Cornivelli (Medford, Massachusetts) |
| ABSTRACT | Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 autoantibodies to cardiac troponin I (cTnI). |
| FILED | Friday, July 15, 2011 |
| APPL NO | 13/184115 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420334 | D'Souza-Schorey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Crislyn D'Souza-Schorey (Granger, Indiana); James W. Clancy (South Bend, Indiana); Vandhana Muralidharan-Chari (Granger, Indiana) |
| ASSIGNEE(S) | University of Notre Dame (Notre Dame, Indiana) |
| INVENTOR(S) | Crislyn D'Souza-Schorey (Granger, Indiana); James W. Clancy (South Bend, Indiana); Vandhana Muralidharan-Chari (Granger, Indiana) |
| ABSTRACT | The present application relates to the isolation and analysis of populations of microvesicles, such as populations of microvesicles that are shed by tumor cells and contain the protein ARF6. Invasive microvesicles from tumor cells contain a variety of specific proteins, including ARF6. |
| FILED | Tuesday, November 09, 2010 |
| APPL NO | 12/942858 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420339 | O'Connor et al. |
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| FUNDED BY |
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| APPLICANT(S) | John O'Connor (New Rochelle, New York); Steven Birken (Dumont, New Jersey); Galina Kovalevskaya (Bronx, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | John O'Connor (New Rochelle, New York); Steven Birken (Dumont, New Jersey); Galina Kovalevskaya (Bronx, New York) |
| ABSTRACT | The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample. |
| FILED | Friday, April 13, 2012 |
| APPL NO | 13/446723 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420340 | Handfield et al. |
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| FUNDED BY |
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| APPLICANT(S) | Martin Handfield (Gainesville, Florida); Jeffrey Daniel Hillman (Gainesville, Florida); Ann Progulske-Fox (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation (Gainesville, Florida) |
| INVENTOR(S) | Martin Handfield (Gainesville, Florida); Jeffrey Daniel Hillman (Gainesville, Florida); Ann Progulske-Fox (Gainesville, Florida) |
| ABSTRACT | Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by Actinobacillus actinomycetemcomitans. |
| FILED | Friday, May 20, 2011 |
| APPL NO | 13/112288 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420391 | Tuschl et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas Tuschl (Goettingen, Germany); Phillip D. Zamore (Northborough, Massachusetts); Phillip A. Sharp (Newton, Massachusetts); David P. Bartel (Brookline, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V. (Munich, Germany) |
| INVENTOR(S) | Thomas Tuschl (Goettingen, Germany); Phillip D. Zamore (Northborough, Massachusetts); Phillip A. Sharp (Newton, Massachusetts); David P. Bartel (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications. |
| FILED | Monday, October 04, 2010 |
| APPL NO | 12/897754 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420395 | Calos |
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| FUNDED BY |
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| APPLICANT(S) | Michele Calos (Stanford, California) |
| ASSIGNEE(S) | Poetic Genetics, Inc. (Burlingame, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Michele Calos (Stanford, California) |
| ABSTRACT | The subject invention provides a unidirectional site-specific integration system for integrating a nucleic acid into the genome of a target cell. The provided systems include a (1) a mutant, unidirectional site specific integrase, which can be provided by an integrase vector encoding the mutant integrase and (2) a targeting vector that includes: (a) a nucleic acid to be integrated; and (b) a vector attachment site, where the targeting vector attachment site serves as a substrate for the mutant, unidirectional site-specific integrase. In using the subject systems for site-specific integration, the targeting vector and integrase are introduced into the target cell and the cell is maintained under conditions sufficient to provide for site-specific integration of the nucleic acid into the target cell genome via a recombination event mediated by the site-specific integrase. Also provided are kits that include the subject systems. The subjects systems, methods and kits find use in a variety of different applications, several representative ones of which are described in detail as well. |
| FILED | Friday, December 03, 2004 |
| APPL NO | 11/003941 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/440 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420591 | Kufe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donald W. Kufe (Wellesley, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Donald W. Kufe (Wellesley, Massachusetts) |
| ABSTRACT | The invention provides methods of identifying and making compounds that inhibit the interaction between MUC1 and galectin-3. Also embraced by the invention are in vivo and in vitro methods of inhibiting such an interaction and of inhibiting the expression of galectin-3 by a cell. |
| FILED | Friday, December 07, 2007 |
| APPL NO | 12/517762 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420607 | Carlson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Russell W. Carlson (Athens, Georgia); Geert-Jan Boons (Athens, Georgia); Conrad Quinn (Lilburn, Georgia); Mahalakshmi Vasan (Athens, Georgia); Margreet A. Wolfert (Athens, Georgia); Biswa Choudhury (Athens, Georgia); Elmar Kannenberg (Athens, Georgia); Christine Leoff (Athens, Georgia); Alok Mehta (Athens, Georgia); Elke Saile (Athens, Georgia); Jana Rauvolfova (Braselton, Georgia); Patricia Wilkins (Duluth, Georgia); Alex J. Harvey (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Russell W. Carlson (Athens, Georgia); Geert-Jan Boons (Athens, Georgia); Conrad Quinn (Lilburn, Georgia); Mahalakshmi Vasan (Athens, Georgia); Margreet A. Wolfert (Athens, Georgia); Therese Buskas (Athens, Georgia); Biswa Choudhury (Athens, Georgia); Elmar Kannenberg (Athens, Georgia); Christine Leoff (Athens, Georgia); Alok Mehta (Athens, Georgia); Elke Saile (Athens, Georgia); Jana Rauvolfova (Braselton, Georgia); Patricia Wilkins (Duluth, Georgia) |
| ABSTRACT | The present invention presents the isolation, characterization and synthesis of oligosaccharides of Bacillus anthracis. Also presented are antibodies that bind to such saccharide moieties and various methods of use for such saccharide moieties and antibodies. |
| FILED | Wednesday, December 24, 2008 |
| APPL NO | 12/317693 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420611 | Lowenstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pedro Lowenstein (Los Angeles, California); Maria Castro (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Pedro Lowenstein (Los Angeles, California); Maria Castro (Los Angeles, California) |
| ABSTRACT | Described herein are compositions and methods for the treatment of cancer, and particularly brain cancer (e.g., glioma) in a mammal. In various embodiments of the invention, a combined therapeutic approach including TK with systemic ganciclovir administration and Flt3L are used in connection with gene therapeutic techniques or direct peptide injection for the aforementioned indications. Kits useful in practicing the inventive method are also disclosed, as are animal models useful for studying brain cancer. |
| FILED | Friday, August 12, 2005 |
| APPL NO | 11/572391 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420612 | Chien et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kenneth Chien (Cambridge, Massachusetts); Lisa Lesniewski (Boulder, Colorado); Jerrold Olefsky (Solana Beach, California); Mohammad Pashmforoush (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth Chien (Cambridge, Massachusetts); Lisa Lesniewski (Boulder, Colorado); Jerrold Olefsky (Solana Beach, California); Mohammad Pashmforoush (Los Angeles, California) |
| ABSTRACT | Provided are methods of treating insulin resistance or type II diabetes. Disrupting CAP in the macrophage can alter the inflammatory response associated with impaired insulin action and ultimately result in improved insulin action in target tissues. One aspect of the invention involves administering a CAP antagonist to a patient afflicted with insulin resistance or type II diabetes in an amount sufficient to improve insulin action in target tissues. |
| FILED | Monday, January 22, 2007 |
| APPL NO | 11/625795 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420613 | Gan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Li Gan (San Francisco, California); Lennart Mucke (San Francisco, California) |
| ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
| INVENTOR(S) | Li Gan (San Francisco, California); Lennart Mucke (San Francisco, California) |
| ABSTRACT | The present invention provides methods for reducing the level of amyloid beta protein in a cell or tissue, the methods generally involving contacting the cell or tissue with an agent that reduces cystatin C levels and/or activity. The present invention provides methods for treating Alzheimer's disease (AD), and methods for treating cerebral angiopathy, in an individual, the methods generally involving administering to an individual having AD a therapeutically effective amount of an agent that reduces cystatin C levels and/or activity. The present invention further provides methods for identifying an agent that reduces cystatin C levels and/or activity. |
| FILED | Thursday, November 15, 2007 |
| APPL NO | 12/447241 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420614 | Van De Water et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Livingston Van De Water (Old Chatham, New York); Ganary Dabiri (Albany, New York); Christopher E. Turner (Chittenago, New York) |
| ASSIGNEE(S) | Albany Medical College (Albany, New York) |
| INVENTOR(S) | Livingston Van De Water (Old Chatham, New York); Ganary Dabiri (Albany, New York); Christopher E. Turner (Chittenago, New York) |
| ABSTRACT | The present invention provides compositions and methods for inhibiting or reversing fibrotic disorders by administering a Hic-5 antagonist to a mammal in need thereof. The invention also includes methods for screening compounds to identify Hic-5 antagonists useful in inhibiting or reversing fibrotic disorders. |
| FILED | Friday, February 15, 2008 |
| APPL NO | 12/527307 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420616 | Kotb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Malak Kotb (Ft. Thomas, Kentucky); Arthur M. Geller (Ft. Thomas, Kentucky) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Malak Kotb (Ft. Thomas, Kentucky); Arthur M. Geller (Ft. Thomas, Kentucky) |
| ABSTRACT | The presently disclosed subject matter generally relates to methods and compositions for modulating MAT II activity. More particularly, the presently disclosed subject matter relates to methods and compositions for inhibiting the expression of MAT II β subunit in a subject via RNAi by administering siRNA or shRNA molecules directed to MAT II β subunit. In some embodiments, the methods and compositions of the presently disclosed subject matter generally relates to the treatment of cancer. More particularly, the methods and compositions of the presently disclosed subject matter relates to the inhibition of MAT II β subunit for the treatment of leukemia. |
| FILED | Tuesday, April 07, 2009 |
| APPL NO | 12/936780 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420620 | Tosato et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Giovanna Tosato (Bethesda, Maryland); Masashi Narazaki (Minoo, Japan) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Giovanna Tosato (Bethesda, Maryland); Masashi Narazaki (Minoo, Japan) |
| ABSTRACT | Disclosed is a hetero-bifunctional ligand for use in inducing internalization of a target receptor. The hetero-bifunctional ligand includes a target receptor-binding agent that specifically binds the target receptor linked to an internalizing receptor-binding agent that specifically binds to an internalizing receptor, where the two binding agents are non-identical. Also disclosed is a method of inducing the internalization of a target receptor on a cell. The method includes contacting a cell with a hetero-bifunctional ligand, where binding of the hetero-bifunctional ligand induces internalization of a target receptor of the cell. Also disclosed a method of treating a disease or condition associated with a target receptor using the disclosed hetero-bifunctional ligand and pharmaceutical compositions including a hetero-bifunctional ligand. |
| FILED | Friday, January 23, 2009 |
| APPL NO | 12/864492 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420664 | Goblyos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aniko Goblyos (Zoetermeer, Netherlands); Johannes Brussee (Rijnsburg, Netherlands); Adriaan P. Ijzerman (Haarlem, Netherlands); Zhan-Guo Gao (Rockville, Maryland); Kenneth Jacobson (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of America, represented by the Secretary, Dept. of Health and Human Services (Washington, District of Columbia); Universiteit Leiden (Leiden, Netherlands) |
| INVENTOR(S) | Aniko Goblyos (Zoetermeer, Netherlands); Johannes Brussee (Rijnsburg, Netherlands); Adriaan P. Ijzerman (Haarlem, Netherlands); Zhan-Guo Gao (Rockville, Maryland); Kenneth Jacobson (Silver Spring, Maryland) |
| ABSTRACT | The present invention relates to allosteric modulation of A3 adenosine receptor (A3AR) and provides for the use of an A3 adenosine receptor modulator (A3RM), for the preparation of pharmaceutical compositions for modulating the A3AR in a subject, as well as pharmaceutical compositions comprising the same and therapeutic methods comprising administering to a subject an amount of an A3RM, the amount being effective to modulate A3AR activity. The A3RM according to the invention are 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives. The invention also provides some of such novel 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives. |
| FILED | Monday, July 28, 2008 |
| APPL NO | 12/219772 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/293 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420678 | Mahadevan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Daruka Mahadevan (Tucson, Arizona); Emmanuelle J. Meuillet (Oro Valley, Arizona); Eugene A. Mash, Jr. (Tucson, Arizona); Vijay M. Gohkale (Tucson, Arizona); Garth Powis (Houston, Texas); Shuxing Zhang (Pearland, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Daruka Mahadevan (Tucson, Arizona); Emmanuelle J. Meuillet (Oro Valley, Arizona); Eugene A. Mash, Jr. (Tucson, Arizona); Vijay M. Gohkale (Tucson, Arizona); Garth Powis (Houston, Texas); Shuxing Zhang (Pearland, Texas) |
| ABSTRACT | Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein. |
| FILED | Tuesday, April 14, 2009 |
| APPL NO | 12/937898 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/363 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420680 | Liotta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dennis C. Liotta (Atlanta, Georgia); James P. Snyder (Atlanta, Georgia); Stephen F. Traynelis (Decatur, Georgia); Lawrence Wilson (Atlanta, Georgia); Cara Mosley (Atlanta, Georgia); Raymond J. Dingledine (Atlanta, Georgia); Yesim Altas Tahirovic (Decatur, Georgia); Scott J. Myers (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); NeurOp, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Dennis C. Liotta (Atlanta, Georgia); James P. Snyder (Atlanta, Georgia); Stephen F. Traynelis (Decatur, Georgia); Lawrence Wilson (Atlanta, Georgia); Cara Mosley (Atlanta, Georgia); Raymond J. Dingledine (Atlanta, Georgia); Yesim Altas Tahirovic (Decatur, Georgia); Scott J. Myers (Atlanta, Georgia) |
| ABSTRACT | Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of disorders associated with NMDA receptor activity, including neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof are provided: wherein: each (L)k-Ar1 is a substituted or unsubstituted, mono or bicyclic aryl or heteroaryl; W is a bond, alkyl, or alkenyl; X is a bond, NR1 or O and each R1 and R2 is independently H, alkyl, alkenyl or aralkyl or R1 and R2 taken together form a 5-8 membered ring; R3−R6 are selected from certain specific substituents or a carbonyl; Y is a bond, O, S, SO, SO2, CH2, NH, N(alkyl), or NHC(═O); and Z is OH, NR6R7, NR8SO2(alkyl), NR8C(O)NR6R7, NR8C(O)O(alkyl), NR8-dihydrothiazole, or NR8-dihydroimidazole or wherein Z can fuse with Ar2 to form selected heterocycles. |
| FILED | Monday, June 30, 2008 |
| APPL NO | 12/165308 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/376 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420774 | Murphy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William L. Murphy (Madison, Wisconsin); Jae Sung Lee (Madison, Wisconsin); Mark D. Markel (Middleton, Wisconsin); Ben K. Graf (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | William L. Murphy (Madison, Wisconsin); Jae Sung Lee (Madison, Wisconsin); Mark D. Markel (Middleton, Wisconsin); Ben K. Graf (Madison, Wisconsin) |
| ABSTRACT | A modular peptide design strategy wherein the modular peptide has two functional units separated by a spacer portion is disclosed. More particularly, the design strategy combines a hydroxyapatite-binding portion and a biomolecule-derived portion. The modular peptides have improved non-covalent binding to the surface of the HA-based materials, and are capable of initiating osteogenesis, angiogenesis, and/or osteogenic differentiation. |
| FILED | Tuesday, December 01, 2009 |
| APPL NO | 12/628666 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420776 | Weissman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Allan Weissman (Bethesda, Maryland); Jennifer Mariano (Frederick, Maryland); Bo Chen (Frederick, Maryland); Yien Che Tsai (Frederick, Maryland) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Allan Weissman (Bethesda, Maryland); Jennifer Mariano (Frederick, Maryland); Bo Chen (Frederick, Maryland); Yien Che Tsai (Frederick, Maryland) |
| ABSTRACT | The present invention features isolated nucleic acid molecules, designated G2BD nucleic acid molecules, which encode the binding site from the gp78 ubiquitin ligase that binds to the Ube2G2 ubiquitin conjugating enzyme. The invention further provides isolated G2BD proteins and fusion proteins. Still further provided are diagnostic and therapeutic methods, as well as screening assays utilizing compositions of the invention. |
| FILED | Wednesday, April 27, 2005 |
| APPL NO | 11/597453 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420777 | Altieri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dario C. Altieri (Worcester, Massachusetts); Janet Plescia (Meriden, Connecticut); Whitney Salz (Acton, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Dario C. Altieri (Worcester, Massachusetts); Janet Plescia (Meriden, Connecticut); Whitney Salz (Acton, Massachusetts) |
| ABSTRACT | Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds. |
| FILED | Tuesday, February 19, 2008 |
| APPL NO | 12/033210 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/328 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420795 | Rodriguez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Moses Rodriguez (Rochester, Minnesota); David J. Miller (Ridgeway, Wisconsin); Larry R. Pease (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Moses Rodriguez (Rochester, Minnesota); David J. Miller (Ridgeway, Wisconsin); Larry R. Pease (Rochester, Minnesota) |
| ABSTRACT | Antibodies, and particularly human antibodies, are disclosed that demonstrate activity in the treatment of demyelinating diseases as well as other diseases of the central nervous system that are of viral, bacterial or idiopathic origin, including neural dysfunction caused by spinal cord injury. Neuromodulatory agents are set forth that include and comprise a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, a hapten, active fragments thereof, agonists thereof, mimics thereof, monomers thereof and combinations thereof. The neuromodulatory agent has one or more of the following characteristics: it is capable of inducing remyelination; binding to neural tissue; promoting Ca++ signaling with oligodendrocytes; and promoting cellular proliferation of glial cells. Amino acid and DNA sequences of exemplary antibodies are disclosed. Methods are described for treating demyelinating diseases, and diseases of the central nervous system of humans and domestic animals, using polyclonal IgM antibodies and human monoclonal antibodies sHIgm22(LYM 22), sHIgm46(LYM46) ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7, MSI19E5 and MSI10E10, active fragments thereof and the like. The invention also extends to the use of human antibodies, fragments, peptide derivatives and like materials, and their use in diagnostic and therapeutic applications, including screening assays for the discovery of additional antibodies that bind to cells of the nervous system, particularly oligodendrocytes. |
| FILED | Thursday, July 29, 2010 |
| APPL NO | 12/845977 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.530 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420804 | Balakumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arumugham Balakumar (Raleigh, North Carolina); Kannan Muthukumaran (Raleigh, North Carolina); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Arumugham Balakumar (Raleigh, North Carolina); Kannan Muthukumaran (Raleigh, North Carolina); Jonathan S. Lindsey (Raleigh, North Carolina) |
| ABSTRACT | A method of making a 5-formylporphyrin, comprises the steps of: condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin. Products and intermediates useful in such methods, along with methods of making such intermediates, are also described. |
| FILED | Friday, February 25, 2011 |
| APPL NO | 13/035235 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420839 | DeLuca et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hector F. DeLuca (Deerfield, Wisconsin); Rafal Barycki (Madison, Wisconsin); James B. Thoden (Madison, Wisconsin); Hazel M. Holden (Fitchburg, Wisconsin) |
| ABSTRACT | A method of purifying 1α-hydroxy-2-methylene-18,19-dinor-homopregnacalciferol to obtain 1α-hydroxy-2-methylene-18,19-dinor-homopregnacalciferol in crystalline form using precipitation with hexane from ethyl acetate. A method of preparing 1α-hydroxy-2-methylene-18,19-dinor-homopregnacalciferol crystals acceptable for X-ray experiment using precipitation with hexane from benzene by diffusive exchange of the solvents is also described. |
| FILED | Monday, October 01, 2012 |
| APPL NO | 13/632791 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Organic compounds 552/653 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420884 | Charest |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alain Charest (Boston, Massachusetts) |
| ASSIGNEE(S) | Tufts Medical Center Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Alain Charest (Boston, Massachusetts) |
| ABSTRACT | Methods for screening compounds to treat an oncological disorder regulated through a tumor-inducing pathway are provided. The compounds are administered to non-human animal subjects having a disease model, so that the subjects display pathology symptoms that correspond to the oncological disorder in humans. The subjects carry a regulatable transgene expression, of which is associated with tumor formation, and further carry regulatable genes for suppression of tumor formation. The disease-pathology symptoms are induced using a site-specific recombination system to induce expression of the transgene associated with tumor formation and negatively regulate or eliminate the genes for suppression of the tumor formation. The methods further involve analyzing tumor formation in subjects administered the compound and comparing appearance and amount of tumors in the subjects administered the compound with control subjects not administered the compound. Also included are a vector for engineering a disease model and a kit for its use. |
| FILED | Friday, October 16, 2009 |
| APPL NO | 12/580690 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420885 | Clarke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael F. Clarke (Ann Arbor, Michigan); Scott J. Dylla (Mountain View, California); Sanjeev Satyal (San Carlos, California) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Oncomed Pharmaceuticals, Inc. (Redwood City, California) |
| INVENTOR(S) | Michael F. Clarke (Ann Arbor, Michigan); Scott J. Dylla (Mountain View, California); Sanjeev Satyal (San Carlos, California) |
| ABSTRACT | A small percentage of cells within an established solid tumor have the properties of stem cells. These solid tumor stem cells give rise both to more tumor stem cells and to the majority of cells in the tumor that have lost the capacity for extensive proliferation and the ability to give rise to new tumors. Thus, solid tumor heterogeneity reflects the presence of tumor cell progeny arising from a solid tumor stem cell. We have developed a xenograft model in which we have been able to establish tumors from primary tumors via injection of tumor cells in the mammary gland of severely immunodeficient mice. These xenograft assay have allowed us to do biological and molecular assays to characterize clonogenic solid tumor stem cells. We have also developed evidence that strongly implicates the Notch pathway, especially Notch 4, as playing a central pathway in carcinogenesis. |
| FILED | Friday, September 23, 2011 |
| APPL NO | 13/241701 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421006 | Naqwi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Amir A. Naqwi (Eden Prairie, Minnesota); Christopher W. Fandrey (Minneapolis, Minnesota); Zeeshan H. Syedain (Minneapolis, Minnesota) |
| ASSIGNEE(S) | MSP Corporation (Shoreview, Minnesota) |
| INVENTOR(S) | Amir A. Naqwi (Eden Prairie, Minnesota); Christopher W. Fandrey (Minneapolis, Minnesota); Zeeshan H. Syedain (Minneapolis, Minnesota) |
| ABSTRACT | A device for generating sprays of charged droplets, and resulting nanoparticles, the device comprising a first needle connected to an electrical potential line to generate a first spray of charged particles from the first needle, and a second needle spaced apart from and facing the first needle, and connected to an electrical line configured to ground the second needle or to apply a voltage to the second needle that is the same polarity as the voltage applied to the first needle. The device also comprising an electric field modifier connected to the first needle, and configured to modify an electrical field to generate a second spray of charged particles from the second needle. |
| FILED | Tuesday, November 09, 2010 |
| APPL NO | 12/942164 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421313 | Shih et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Wan Y. Shih (Bryn Mawr, Pennsylvania); Hakki Yegingil (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Wan Y. Shih (Bryn Mawr, Pennsylvania); Hakki Yegingil (Philadelphia, Pennsylvania) |
| ABSTRACT | A piezoelectric energy harvesting device (PEHD) comprising a driving element, conducting element, piezoelectric layer and non-piezoelectric layer capable of converting ambient mechanical energy into electrical energy. The piezoelectric layer may be constructed from PMN-PT or PZT having a thickness of about 1-150 μm. The PEHD may be used to generate about 1 W. The harvested energy may be stored and used to power microelectronic devices and rechargeable battery technologies. |
| FILED | Tuesday, January 24, 2012 |
| APPL NO | 13/357291 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/339 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421855 | Buckland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric L. Buckland (Hickory, North Carolina); Robert H. Hart (Cary, North Carolina); Glenn A. Myers (Durham, North Carolina); Joseph A. Izatt (Raleigh, North Carolina) |
| ASSIGNEE(S) | Bioptigen, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Eric L. Buckland (Hickory, North Carolina); Robert H. Hart (Cary, North Carolina); Glenn A. Myers (Durham, North Carolina); Joseph A. Izatt (Raleigh, North Carolina) |
| ABSTRACT | Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path length adjustment module is coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye length of the subject. Related methods and computer program products are also provided. |
| FILED | Thursday, April 23, 2009 |
| APPL NO | 12/428603 |
| ART UNIT | 2445 — Computer Networks |
| CURRENT CPC | Television 348/78 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422632 | Fowler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian Fowler (San Mateo, California); Andrew May (San Francisco, California) |
| ASSIGNEE(S) | Fluidigm Corporation (South San Francisco, California) |
| INVENTOR(S) | Brian Fowler (San Mateo, California); Andrew May (San Francisco, California) |
| ABSTRACT | An integrated fluidic circuit includes a substrate layer and a first structure coupled to the substrate layer and including a plurality of channels. The first structure is configured to provide for flow of one or more materials through the plurality of channels. The integrated fluidic circuit also includes a second structure coupled to the substrate layer. The second structure includes a plurality of control channels configured to receive an actuation pressure. The integrated fluidic circuit is characterized by a thickness of less than 1.5 mm. |
| FILED | Friday, June 24, 2011 |
| APPL NO | 13/168041 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/79 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423127 | Mahmood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Umar Mahmood (Winchester, Massachusetts); Ralph Weissleder (Peabody, Massachusetts); Rahul A. Sheth (Houston, Texas); Rabi Upadhyay (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Umar Mahmood (Winchester, Massachusetts); Ralph Weissleder (Peabody, Massachusetts); Rahul A. Sheth (Houston, Texas); Rabi Upadhyay (Boston, Massachusetts) |
| ABSTRACT | An imaging system divides image pixels intensities by exposure time to generate image data in units of intensity per time. The imaging system divides a fluorescent light image in intensity per time units by an excitation light image in intensity per time units to provide a quantitative corrected fluorescent light image that is generally invariant to position of an imaging instrument relative to a biological tissue being imaged. |
| FILED | Monday, October 17, 2011 |
| APPL NO | 13/274781 |
| ART UNIT | 3737 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423151 | Greenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Jay Greenberg (Los Angeles, California); Kelly Hobart McClure (Simi Valley, California); James Singleton Little (Saugus, California); Rongqing Dai (Valencia, California); Arup Roy (Valencia, California); Richard Agustin Castro (Pasadena, California); John Reinhold (Tarzana, California); Kea-Tiong Tang (Temple City, California); Sumit Yadav (Los Angeles, California); Chunhong Zhou (Pasadena, California); Dao Min Zhou (Saugus, California); Pishoy Maksy (Sherman Oaks, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert Jay Greenberg (Los Angeles, California); Kelly Hobart McClure (Simi Valley, California); James Singleton Little (Saugus, California); Rongqing Dai (Valencia, California); Arup Roy (Valencia, California); Richard Agustin Castro (Pasadena, California); John Reinhold (Tarzana, California); Kea-Tiong Tang (Temple City, California); Sumit Yadav (Los Angeles, California); Chunhong Zhou (Pasadena, California); Dao Min Zhou (Saugus, California); Pishoy Maksy (Sherman Oaks, California) |
| ABSTRACT | In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue in not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes as continued use may result in neural and further electrode damage. Systems and stimulator control mechanisms to prevent damage to neural tissue. |
| FILED | Sunday, October 28, 2007 |
| APPL NO | 11/926057 |
| ART UNIT | 3766 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/63 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423167 | Sanders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joan E. Sanders (Sammamish, Washington); Michael R. Severance (Seattle, Washington); Timothy R. Myers (Seattle, Washington); George Turkiyyah (Seattle, Washington); Elizabeth A. Sorenson (Ramona, California); Ellen L. Lee (Corvallis, Oregon) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Joan E. Sanders (Sammamish, Washington); Michael R. Severance (Seattle, Washington); Timothy R. Myers (Seattle, Washington); George Turkiyyah (Seattle, Washington); Elizabeth A. Sorenson (Ramona, California); Ellen L. Lee (Corvallis, Oregon) |
| ABSTRACT | For use in connection with evaluating prosthetic sockets (and other objects) designed and fabricated with computer aided design and manufacturing software, the shape of a socket is accurately scanned and digitized. The scanned data are then compared to either an electronic shape data file, or to the shape of another socket, a positive model of a residual limb (or socket), or a residual limb. Differences detected during the comparison can then be applied to revise the design or fabrication of the socket, to more accurately achieve a desired shape that properly fits the residual limb of a patient and can be used to solve the inverse problem by correcting for observed errors of a specific fabricator before a socket is produced. The digitizing process is implemented using a stylus ball that contacts a surface of the socket to produce data indicating the three-dimensional shape of the socket. |
| FILED | Wednesday, July 22, 2009 |
| APPL NO | 12/507560 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/98 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08418288 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel W. Miller (Oriental, North Carolina); Steve K. McAllaster (Rancho Cucamonga, California); Jerry D. Slater (Redlands, California); Nickolas S. Rigney (Redlands, California); Daniel C. Anderson (Loma Linda, California); Michael F. Moyers (Colton, California) |
| ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
| INVENTOR(S) | Daniel W. Miller (Oriental, North Carolina); Steve K. McAllaster (Rancho Cucamonga, California); Jerry D. Slater (Redlands, California); Nickolas S. Rigney (Redlands, California); Daniel C. Anderson (Loma Linda, California); Michael F. Moyers (Colton, California) |
| ABSTRACT | A radiation treatment system (100) for accurately delivering radiation to a targeted site within a cancer patient (108) that includes a modular patient support system and a patient positioner (114). The modular patient support system includes a modularly expandable patient pod (200) and at least one immobilization device, such as, for example, a rigid moldable foam cradle (350). The patient pod (200) includes a generally hemi-cylindrical support shell (212) that extends longitudinally between proximal edge (214) and distal edge (216), and transversely between two lateral edges (222, 224). In one embodiment, the lateral edges (222, 224) are tapered to minimize edge effects that result when radiation beams traverse the lateral edges (222, 224). |
| FILED | Friday, January 06, 2012 |
| APPL NO | 13/345090 |
| ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Beds 05/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418389 | Lukman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hansen Lukman (Parsippany, New Jersey); James R. Connolly (Bloomfield, New Jersey); Kevin Russell (Jersey City, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Hansen Lukman (Parsippany, New Jersey); James R. Connolly (Bloomfield, New Jersey); Kevin Russell (Jersey City, New Jersey) |
| ABSTRACT | A recoil-reducing weapon may include a housing and a receiver translatably disposed in the housing. A barrel may have one end fixed to the receiver and be translatable with respect to the housing. A spring stop may be fixed to the barrel forward of the housing and a spring may be disposed between the spring stop and a front of the housing. An operating group with a gear rack may be translatably disposed in the receiver. A longitudinal member may have one end fixed to the operating group. A counter-mass may have a second gear rack and an opening therein for receiving the longitudinal member. A second spring may be disposed around the longitudinal member. One end of the second spring may bear against the operating group and another end of the second spring may bear against the counter-mass. A pinion gear may be rotatably fixed to the receiver and operable to mesh with the gear rack and the second gear rack. |
| FILED | Tuesday, June 21, 2011 |
| APPL NO | 13/165192 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/1.60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418392 | Carter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Hansbrough Carter (Jarrettsville, Maryland); William Steinle DeRosset (Aberdeen, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert Hansbrough Carter (Jarrettsville, Maryland); William Steinle DeRosset (Aberdeen, Maryland) |
| ABSTRACT | An inventive process is provided for creating residual compressive stress at a surface of a structure without resort to custom mandrels and dangerous high-pressure fluids. The inventive process yields autofrettage of a structure such as a tube, gun barrel and the like, the structure having an outer surface and an inner surface. |
| FILED | Monday, July 21, 2008 |
| APPL NO | 12/176608 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/76.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418547 | Kysar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey William Kysar (New York, New York); James C. Hone (New York, New York); Changgu Lee (New York, New York); Xiaoding Wei (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jeffrey William Kysar (New York, New York); James C. Hone (New York, New York); Changgu Lee (New York, New York); Xiaoding Wei (New York, New York) |
| ABSTRACT | Force, pressure, or stiffness measurement or calibration can be provided, such as by using a graphene or other sheet membrane, which can provide a specified number of monolayers suspended over a substantially circular well. In an example, the apparatus can include a substrate, including a substantially circular well. A deformable sheet membrane can be suspended over the well. The membrane can be configured to include a specified integer number of one or more monolayers. A storage medium can comprise accompanying information about the suspended membrane or the substrate that, with a deflection displacement response of the suspended membrane to an applied force or pressure, provides a measurement of the applied force or pressure. |
| FILED | Thursday, August 06, 2009 |
| APPL NO | 13/057701 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/159 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418622 | Pham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Pham (Randolph, New Jersey); Gregory Stunzenas (Pocono, Pennsylvania); Tan Vuong (Hackettstown, New Jersey); Ernest Baker (Wantage, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | James Pham (Randolph, New Jersey); Gregory Stunzenas (Pocono, Pennsylvania); Tan Vuong (Hackettstown, New Jersey); Ernest Baker (Wantage, New Jersey) |
| ABSTRACT | A simple, inexpensive, device and method of use thereof for disrupting the jet of a shaped charge and thereby significantly reducing the penetrating capability by over 90% thereof; thus providing a means to mitigate the damage caused by the premature or accidental jetting of the shaped charge. The device has a central support, along which radiate a plurality of increasing radius, generally hemi-circular, thin discs—such that the outline of the disc edges thereof form a cone that models the interior of the hollow open mouth of the shaped charge—importantly, the discs are staggered along the length of the central support. The device, which can be molded of inexpensive plastic, must be lodged fully within the hollow open mouth of the shaped charge at the time of the premature or accidental jetting—to provide the desired mitigation. |
| FILED | Friday, April 29, 2011 |
| APPL NO | 13/097231 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418642 | Vosburgh |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederick Vosburgh (Durham, North Carolina) |
| ASSIGNEE(S) | iRobot Corporation (Bedford, Massachusetts) |
| INVENTOR(S) | Frederick Vosburgh (Durham, North Carolina) |
| ABSTRACT | An unmanned submersible vehicle for use in a body of liquid having a top surface and in air overlying the top surface includes a hull, an integral antenna, and an antenna positioning system. The hull has first and second opposed ends. The hull includes a first hull portion adjacent the first end and a second hull portion adjacent the second end. The antenna is disposed within the first hull portion and/or is mounted on the first hull portion. The antenna positioning system is configured to reorient the hull from a transit position to a signal position. When the hull is in the signal position: the first hull portion and the antenna are disposed above the second hull portion a greater vertical distance than when the hull is in the transit position; the first hull portion and the antenna are disposed above the top surface and in the air while at least the second hull portion remains submerged in the body of liquid; and the antenna is operative to emit signals through the air above the top surface and/or to receive signals through the air above the top surface. |
| FILED | Thursday, May 07, 2009 |
| APPL NO | 12/437181 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/312 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418967 | Hemmelgarn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher Douglas Hemmelgarn (South Charleston, Ohio); Bryan Michael Pelley (Miamisburg, Ohio) |
| ASSIGNEE(S) | Cornerstone Research Group, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Christopher Douglas Hemmelgarn (South Charleston, Ohio); Bryan Michael Pelley (Miamisburg, Ohio) |
| ABSTRACT | Embodiments of the present airfoil structural insert comprise an airfoil structural insert frame, a skin surface disposed about the airfoil structural insert frame, at least one attachment point operable for coupling to an aerodynamic structure, a leading edge disposed on one end of the airfoil structural insert frame, a trailing edge disposed on an opposite end of the airfoil structural insert frame, and at least one structural element configured to support the skin surface, wherein said structural element undergoes at least one nonlinear shape change from a first shape to a deflected shape. |
| FILED | Friday, August 20, 2010 |
| APPL NO | 12/859966 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/219 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419213 | Rubtsov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladimir Rubtsov (Los Angeles, California); Michael Levin (Los Angeles, California); Gennady Sigal (Oakville, Canada) |
| ASSIGNEE(S) | Vladimir Rubtsov (Los Angeles, California) |
| INVENTOR(S) | Vladimir Rubtsov (Los Angeles, California); Michael Levin (Los Angeles, California); Gennady Sigal (Oakville, Canada) |
| ABSTRACT | Apparatus and method for using a light source having spatially separated light emitting areas emitting light at different wavelengths to incapacitate a subject by a pattern of temporal flashing and/or color flashing of the light source. Also, power circuitry and optics particularly suited for flashing light incapacitation are included. |
| FILED | Saturday, October 23, 2010 |
| APPL NO | 12/910796 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Illumination 362/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419270 | Wawrzonek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Wawrzonek (Bondsville, Massachusetts); H. Eric Sonnichsen (Marlborough, Massachusetts); Robert L. Murner (Wilbraham, Massachusetts) |
| ASSIGNEE(S) | Test Devices, Inc. (Hudson, Massachusetts) |
| INVENTOR(S) | Paul Wawrzonek (Bondsville, Massachusetts); H. Eric Sonnichsen (Marlborough, Massachusetts); Robert L. Murner (Wilbraham, Massachusetts) |
| ABSTRACT | A test facility includes a heat source to thermally load a test object being mechanically loaded by rotation imposed by a spin test rig. The heat source can be a quartz lamp controlled to provide a thermal load with a differing phase than the mechanical load. Testing cycles can be run for the test object, with impingement cooling permitting the removal of the thermal load between cycles. The test facility emulates operating conditions in a gas turbine engine to impose realistic thermal and mechanical fatigue stress on the test component. |
| FILED | Monday, June 22, 2009 |
| APPL NO | 12/489023 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Thermal measuring and testing 374/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419883 | Day et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen W. Day (Dayton, Ohio); G. Scott Campbell (Dayton, Ohio); Danny E. Tilton (Dayton, Ohio); Frederick Stoll (West Chester, Ohio); Michael Sheppard (Dayton, Ohio); Robin Banerjee (Centerville, Ohio) |
| ASSIGNEE(S) | Milliken and Company (Spartanburg, South Carolina) |
| INVENTOR(S) | Stephen W. Day (Dayton, Ohio); G. Scott Campbell (Dayton, Ohio); Danny E. Tilton (Dayton, Ohio); Frederick Stoll (West Chester, Ohio); Michael Sheppard (Dayton, Ohio); Robin Banerjee (Centerville, Ohio) |
| ABSTRACT | A fiber reinforced core panel is formed from strips of plastics foam helically wound with layers of rovings to form webs which may extend in a wave pattern or may intersect transverse webs. Hollow tubes may replace foam strips. Axial rovings cooperate with overlying helically wound rovings to form a beam or a column. Wound roving patterns may vary along strips for structural efficiency. Wound strips may alternate with spaced strips, and spacers between the strips enhance web buckling strength. Continuously wound rovings between spaced strips permit folding to form panels with reinforced edges. Continuously wound strips are helically wrapped to form annular structures, and composite panels may combine both thermoset and thermoplastic resins. Continuously wound strips or strip sections may be continuously fed either longitudinally or laterally into molding apparatus which may receive skin materials to form reinforced composite panels. |
| FILED | Thursday, November 08, 2007 |
| APPL NO | 11/983317 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/264 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419919 | Boss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pamela A. Boss (San Diego, California); Frank E. Gordon (San Diego, California); Stanislaw Szpak (Poway, California); Lawrence Parker Galloway Forsley (San Diego, California) |
| ASSIGNEE(S) | JWK International Corporation (Annandale, Virginia); The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Pamela A. Boss (San Diego, California); Frank E. Gordon (San Diego, California); Stanislaw Szpak (Poway, California); Lawrence Parker Galloway Forsley (San Diego, California) |
| ABSTRACT | A method may include the steps of supplying current to the electrodes of an electrochemical cell according to a first charging profile, wherein the electrochemical cell has an anode, cathode, and electrolytic solution; maintaining a generally constant current between the electrodes; exposing the cell to an external field either during or after the termination of the deposition of deuterium absorbing metal on the cathode; and supplying current to the electrodes according to a second charging profile during the exposure of the cell to the external field. The electrolytic solution may include a metallic salt including palladium, and a supporting electrolyte, each dissolved in heavy water. The cathode may comprise a second metal that does not substantially absorb deuterium, such as gold. The external field may be a magnetic field. |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/859499 |
| ART UNIT | 1756 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420023 | Tatarchuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce Tatarchuk (Auburn, Alabama); Hongyun Yang (Auburn, Alabama); Ranjeeth Kalluri (Morrisville, North Carolina); Donald Cahela (Auburn, Alabama) |
| ASSIGNEE(S) | Auburn University (Auburn, Alabama); Intramicron, Inc. (Auburn, Alabama) |
| INVENTOR(S) | Bruce Tatarchuk (Auburn, Alabama); Hongyun Yang (Auburn, Alabama); Ranjeeth Kalluri (Morrisville, North Carolina); Donald Cahela (Auburn, Alabama) |
| ABSTRACT | A vessel packed with a microfibrous media made of micron-sized highly conductive fibers, which are able (and may be used) to immobilize various reactive materials including catalysts, sorbents, electrocatalysts, and other chemically reactive solids. The vessel enables fine temperature control and a uniform temperature profile for a range of highly endothermic or exothermic chemical reactions, sorptions, separation processes, mixing operations, and heat transfer applications. |
| FILED | Friday, November 05, 2010 |
| APPL NO | 12/940792 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/211 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420121 | Thayumanavan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sankaran Thayumanavan (Amherst, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Sankaran Thayumanavan (Amherst, Massachusetts) |
| ABSTRACT | Drug delivery vehicles that release one or more drugs, e.g., an opioid antagonist and/or an opioid, in response to changes in the chemistry of body fluids, specifically in response to changes in the partial pressure of CO2 in the environment of the hydrogel are described. The drug delivery vehicles include hydrogels that swell or shrink in response to changes in the partial pressure of CO2 in their environment, thus regulating release of an entrapped drug. |
| FILED | Wednesday, July 28, 2010 |
| APPL NO | 12/845126 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/487 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420124 | DeSimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Durham, North Carolina); Benjamin W. Maynor (Durham, North Carolina); Larkin E. Euliss (Chapel Hill, North Carolina); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Durham, North Carolina); Benjamin W. Maynor (Durham, North Carolina); Larkin E. Euliss (Chapel Hill, North Carolina); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Friday, July 06, 2007 |
| APPL NO | 11/825469 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/499 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420595 | Kopke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard Dana Kopke (Oklahoma City, Oklahoma); Robert A. Floyd (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| INVENTOR(S) | Richard Dana Kopke (Oklahoma City, Oklahoma); Robert A. Floyd (Oklahoma City, Oklahoma) |
| ABSTRACT | The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition includes compounds which function as free radical traps such as phenyl butyl nitrone (PBN), free radical scavengers, such as edaravone, resveratrol, ebselen and iron chelator and compounds from the family of antioxidant compounds including, but not limited to, N-acetylcysteine (NAC), Acetyl-L-Carnitine (ALCAR), glutathione monoethylester, ebselen, D-methionine and carbamathione. The compositions of the current invention may be delivered by injections or orally. |
| FILED | Wednesday, July 25, 2007 |
| APPL NO | 12/374970 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420840 | Olson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edwin S. Olson (Grand Forks, North Dakota) |
| ASSIGNEE(S) | Energy and Environmental Research Center Foundation (, None) |
| INVENTOR(S) | Edwin S. Olson (Grand Forks, North Dakota) |
| ABSTRACT | A method comprising providing a starting composition comprising a polyunsaturated fatty acid, a polyunsaturated fatty ester, a carboxylate salt of a polyunsaturated fatty acid, a polyunsaturated triglyceride, or a mixture thereof; self-metathesizing the starting composition or cross-metathesizing the starting composition with at least one short-chain olefin in the presence of a metathesis catalyst to form self-/cross-metathesis products comprising: cyclohexadiene; at least one olefin; and one or more acid-, ester-, or salt-functionalized alkene; and reacting cyclohexadiene to produce at least one cycloalkane or cycloalkane derivatives. A method for producing cycloalkanes for jet fuel by providing a starting composition comprising at least one selected from the group consisting of algal and polyunsaturated vegetable oils, subjecting the starting composition to metathesis to produce metathesis product comprising at least one olefin, cyclohexadiene, and at least one acid-, ester-, or salt-functionalized alkene, and reacting the at least one olefin and cyclohexadiene to form cycloalkane(s). |
| FILED | Friday, December 02, 2011 |
| APPL NO | 13/309642 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 554/163 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420843 | Snow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arthur W Snow (Alexandria, Virginia); Edward E Foos (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Arthur W Snow (Alexandria, Virginia); Edward E Foos (Alexandria, Virginia) |
| ABSTRACT | The compound is a silane surface treatment agent and is useful for modifying the surfaces of silicon oxide and other metal oxides with hexafluorodimethyl carbinol functional groups. Additionally provided is a surface treatment procedure that effectively bonds it and other alkoxysilanes via homogeneous and heterogeneous amine catalysis onto metal oxide surfaces. |
| FILED | Monday, May 17, 2010 |
| APPL NO | 12/781348 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 556/466 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420977 | Bradley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy Bradley (Loogootee, Indiana); Eric Hillenbrand (Evansville, Indiana) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Timothy Bradley (Loogootee, Indiana); Eric Hillenbrand (Evansville, Indiana) |
| ABSTRACT | A modulation device for directing a mobile tracking device away from an asset is provided. The modulation device includes a continuous wave laser source whose output is directed at a seeker head of the mobile tracking device. The modulation device causes the generation of localized sources within the mobile tracking device and confuses the mobile tracking device as to the true location of the asset. A portable cutting device is disclosed. The portable cutting device may include a portable power supply and a laser source. The portable power supply and laser source of the portable cutting device may be positioned within a backpack and carried by a user. A handheld unit which is coupled to the laser source may be supported by the hands of the operator. The handheld unit provides power generated by the laser source to a barrier to be cut. |
| FILED | Wednesday, May 12, 2010 |
| APPL NO | 12/778643 |
| ART UNIT | 2823 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric heating 219/121.670 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421015 | Scott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Basil H. Scott (Waimea, Hawaii); Randy Wolfshagen (Waimea, Hawaii); Robert E. Swanson (Princeville, Hawaii); Justin Eiler (Waimea, Hawaii) |
| ASSIGNEE(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Basil H. Scott (Waimea, Hawaii); Randy Wolfshagen (Waimea, Hawaii); Robert E. Swanson (Princeville, Hawaii); Justin Eiler (Waimea, Hawaii) |
| ABSTRACT | An event detection and classification system uses a new type of optical sensing component, a Position Sensing Detector Focal Plane Array (PSD-FPA). The PSD-FPA provides for high-speed operation that allows for accurate sensing of fast artifacts that are unique to weapons fire and enables precise location of optical phenomenon. The system detects and classifies events, particularly weapons fire, and rejects false alarms. An optical lens sub-system focuses light onto a PSD-FPA, which senses the photons and generates electrical signals associated with individual elements of the PSD-FPA. These signals are processed to identify and classify weapons-related or other events. Background subtraction, variable gain, time-intensity and time-location correlation, digital filtering, Fourier analysis, and wavelet analysis are all used to successfully classify the events while rejecting false alarms. |
| FILED | Monday, September 15, 2008 |
| APPL NO | 12/283708 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421017 | McGill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | R Andrew McGill (Lorton, Virginia); Graham K Hubler (Highland, Maryland); Michael Papantonakis (Washington, District of Columbia); James S Horwitz (Fairfax, Virginia); Chris Kendziora (Burke, Virginia); Robert Furstenberg (Largo, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | R Andrew McGill (Lorton, Virginia); Graham K Hubler (Highland, Maryland); Michael Papantonakis (Washington, District of Columbia); James S Horwitz (Fairfax, Virginia); Chris Kendziora (Burke, Virginia); Robert Furstenberg (Largo, Maryland) |
| ABSTRACT | A method for non-contact analyte detection by selectively exciting one or more analytes of interest using an IR source optionally operated to produce pulses of light and tuned to at least one specific absorption band without significantly decomposing organic analytes and determining if the analyte is present by comparing emitted photons with an IR detector signal collected one or more times before, during, or after, exciting the analyte. Another embodiment of the present invention provides a method for non-contact analyte detection by selectively exciting analytes of interest using one or more IR sources that are optionally operated to produce pulses of light and tuned to at least one specific wavelength without significantly decomposing organic analytes, wherein the analyte is excited sufficiently to increase the amount of analyte in the gas phase, and wherein the content of the gas is examined to detect the presence of the analyte. |
| FILED | Friday, May 13, 2011 |
| APPL NO | 13/107831 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421018 | McGill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Andrew McGill (Lorton, Virginia); Chris Kendziora (Burke, Virginia); Robert Furstenberg (Largo, Maryland); Michael Papantonakis (Washington, District of Columbia); James S Horwitz (Fairfax, Virginia); Graham K Hubler (Highland, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert Andrew McGill (Lorton, Virginia); Chris Kendziora (Burke, Virginia); Robert Furstenberg (Largo, Maryland); Michael Papantonakis (Washington, District of Columbia); James S Horwitz (Fairfax, Virginia); Graham K Hubler (Highland, Maryland) |
| ABSTRACT | The present invention is directed to a method for non-contact or stand off chemical detection by selectively exciting one or more analytes of interest using an IR source tuned to at least one specific absorption band without significantly decomposing the analyte and determining if the analyte is present by comparing emitted photons with an IR detector signal made before and during or shortly after exciting the analyte. Another embodiment provides a method for non-contact or stand off chemical detection by selectively exciting one or more analytes of interest using an IR source tuned to at least one specific absorption band without significantly decomposing the analyte, wherein the analyte is excited sufficiently to generate a vapor plume, and wherein the plume is examined to detect the presence of the analyte. Additionally, the present invention provides for a system for non-contact or stand off chemical detection. |
| FILED | Tuesday, June 05, 2012 |
| APPL NO | 13/488593 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421052 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhong L. Wang (Marietta, Georgia); Peng Fei (Beijing, China PRC) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Zhong L. Wang (Marietta, Georgia); Peng Fei (Beijing, China PRC) |
| ABSTRACT | An electrical device includes an insulating substrate; an elongated piezoelectric semiconductor structure, a first electrode and a second electrode. A first portion of the elongated piezoelectric semiconductor structure is affixed to the substrate and a second portion of the elongated piezoelectric semiconductor structure extends outwardly from the substrate. The first electrode is electrically coupled to a first end of the first portion of the elongated piezoelectric semiconductor structure. The second electrode is electrically coupled to a second end of the first portion of the elongated piezoelectric semiconductor structure. |
| FILED | Friday, August 13, 2010 |
| APPL NO | 12/855766 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421121 | Chou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yeong-Chang Chou (Irvine, California); Jay Crawford (Long Beach, California); Jane Lee (Torrance, California); Jeffrey Ming-Jer Yang (Cerritos, California); John Bradley Boos (Springfield, Virginia); Nicolas Alexandrou Papanicolaou (Potomac, Maryland) |
| ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| INVENTOR(S) | Yeong-Chang Chou (Irvine, California); Jay Crawford (Long Beach, California); Jane Lee (Torrance, California); Jeffrey Ming-Jer Yang (Cerritos, California); John Bradley Boos (Springfield, Virginia); Nicolas Alexandrou Papanicolaou (Potomac, Maryland) |
| ABSTRACT | An apparatus in one example comprises an antimonide-based compound semiconductor (ABCS) stack, an upper barrier layer formed on the ABCS stack, and a gate stack formed on the upper barrier layer. The upper barrier layer comprises indium, aluminum, and arsenic. The gate stack comprises a base layer of titanium and tungsten formed on the upper barrier layer. |
| FILED | Wednesday, April 18, 2007 |
| APPL NO | 11/788145 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421148 | Harris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher Harris (Solna, Sweden); Andrei Konstantinov (Sollentuna, Sweden); Jan-Olov Svederg (Järfälla, Sweden) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Christopher Harris (Solna, Sweden); Andrei Konstantinov (Sollentuna, Sweden); Jan-Olov Svederg (Järfälla, Sweden) |
| ABSTRACT | A trench metal oxide semiconductor field effect transistor or UMOSFET, includes a buried region that extends beneath the trench and beyond a corner of the trench. The buried region is tied to a source potential of the UMOSFET, and splits the potential realized across the structure. This effectively shields the electric field from the corners of the trench to reduce gate oxide stress, and resultantly improves device performance and reliability. |
| FILED | Friday, September 14, 2007 |
| APPL NO | 11/855595 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/331 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421274 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mingui Sun (Pittsburgh, Pennsylvania); Steven Hackworth (Pittsburgh, Pennsylvania); Robert Sclabassi (Gibsonia, Pennsylvania); Fei Zhang (Gaithersburg, Maryland); Xiaoyu Liu (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Mingui Sun (Pittsburgh, Pennsylvania); Steven Hackworth (Pittsburgh, Pennsylvania); Robert Sclabassi (Gibsonia, Pennsylvania); Fei Zhang (Gaithersburg, Maryland); Xiaoyu Liu (Pittsburgh, Pennsylvania) |
| ABSTRACT | A wireless energy transfer system includes a first energy transfer unit having at least one resonant frequency, a second energy transfer unit having the at least one resonant frequency, and a load. The first wireless energy transfer unit includes a first coil magnetically coupled to a first wireless energy transfer cell, and the second wireless energy transfer unit includes a second coil magnetically coupled to a second wireless energy transfer cell. The first coil receives first energy and through the magnetic coupling between the first coil and the first wireless energy transfer cell, the first wireless energy transfer cell is caused to generate second energy, wherein the second wireless energy transfer cell receives the second energy and through the magnetic coupling between the second wireless energy transfer cell and the second coil, the second coil is caused to provide third electromagnetic wave energy to the load. |
| FILED | Thursday, September 10, 2009 |
| APPL NO | 12/556828 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical transmission or interconnection systems 37/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421306 | Gaitan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dario Felipe Gaitan (Nevada City, California); Robert A. Hiller (Grass Valley, California); Corey Scott (Grass Valley, California); Ernest E. Flores (Grass Valley, California) |
| ASSIGNEE(S) | Impulse Devices, Inc. (Grass Valley, California) |
| INVENTOR(S) | Dario Felipe Gaitan (Nevada City, California); Robert A. Hiller (Grass Valley, California); Corey Scott (Grass Valley, California); Ernest E. Flores (Grass Valley, California) |
| ABSTRACT | Systems and methods for achieving cavitation at high static pressures which may be used in acoustic applications and research such as in liquid metal resonators. Novel preparation and electroplating methods are disclosed to improve boundary layer conditions. A chemical cleaning loop for containment and treatment for oxide removal and to develop a dynamic system for chemically treating liquid metal disposed in a liquid metal loop is also described. A liquid metal handling loop for containment and treatment is provided to maintain cleanliness of bulk liquid metal. |
| FILED | Wednesday, July 07, 2010 |
| APPL NO | 12/832061 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421448 | Tran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nghia Tran (San Diego, California); Sunny Fugate (Albequerque, New Mexico); Marion Ceruti (San Diego, California); Lorraine Duffy (San Diego, California); Hoa Phan (Escondido, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nghia Tran (San Diego, California); Sunny Fugate (Albequerque, New Mexico); Marion Ceruti (San Diego, California); Lorraine Duffy (San Diego, California); Hoa Phan (Escondido, California) |
| ABSTRACT | A system includes a controller, a Hall-effect sensor and transceiver connected to the controller; and a flux-producing element having a plurality of magnetic flux lines emanating therefrom. The system may be secured to or contained within a wearable glove. The flux-producing element may be coupled to an object separate from the wearable glove. The Hall-effect sensor transmits a Hall-effect sensor signal to the controller when the Hall-effect sensor is perpendicular to at least some of the plurality of magnetic flux lines. The Hall-effect sensor signal may include data received from the flux-producing element. The controller transmits a controller signal to the transceiver after receiving the Hall-effect sensor signal. The controller signal may include input from a motion sensor and/or an orientation sensor connected to the controller. The transceiver may transmit the signal to a remote processor. The signal may be used for gesture recognition, information coding, and/or information processing. |
| FILED | Thursday, January 28, 2010 |
| APPL NO | 12/695932 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/207.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421455 | Hovde et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Christian Hovde (Cincinnati, Ohio); Dmitry Budker (El Cerrito, California); James Higbie (Lewisburg, Pennsylvania); Victor Acosta (Albany, California); Micah P. Ledbetter (Oakland, California) |
| ASSIGNEE(S) | Southwest Sciences Incorporated (Santa Fe, New Mexico); Regents of the University of California (Berkeley, California) |
| INVENTOR(S) | David Christian Hovde (Cincinnati, Ohio); Dmitry Budker (El Cerrito, California); James Higbie (Lewisburg, Pennsylvania); Victor Acosta (Albany, California); Micah P. Ledbetter (Oakland, California) |
| ABSTRACT | A magnetometer and concomitant magnetometry method comprising emitting light from a light source, via a pulse generator pulsing light from the light source, directing the pulsed light to an atomic chamber, employing a field sensor in the atomic chamber, and via a signal processing module receiving a signal from the field sensor. |
| FILED | Friday, September 25, 2009 |
| APPL NO | 12/567452 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/305 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421673 | Snow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey M. Snow (Bloomington, Indiana); Michael Schumm (Bloomington, Indiana); William L. Shaff (Bedford, Indiana); Terry Carlson (Washington, Indiana); Carl Baker (Avoca, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey M. Snow (Bloomington, Indiana); Michael Schumm (Bloomington, Indiana); William L. Shaff (Bedford, Indiana); Terry Carlson (Washington, Indiana); Carl Baker (Avoca, Indiana) |
| ABSTRACT | A method and software implementation for spatial pattern analysis. A user-guided test procedure is implemented to measure features of an antenna under test to determine the antenna's far-field patterns. The antenna features include RF amplitude or phase, and position and orientation relative to a receiving object. |
| FILED | Wednesday, December 31, 2008 |
| APPL NO | 12/347659 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/360 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08421692 | Stoneback et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew A. Stoneback (Federal Way, Washington); Ming Chen (Bellevue, Washington); David M. Anderson (Sammamish, Washington) |
| ASSIGNEE(S) | The Boeing Company (Chicaco, Illinois) |
| INVENTOR(S) | Matthew A. Stoneback (Federal Way, Washington); Ming Chen (Bellevue, Washington); David M. Anderson (Sammamish, Washington) |
| ABSTRACT | Apparatus, systems and methods to transmit power and data are provided. A particular apparatus to transmit power and data includes a transmission medium. The transmission medium includes at least one first frequency selective surface (FSS) layer, at least one second FSS layer, and a dielectric layer separating the at least one first FSS layer and the at least one second FSS layer. In a particular embodiment, the apparatus also includes a first coupler coupled to the transmission medium to send a signal along the transmission medium and a second coupler coupled to the transmission medium. The second coupler may receive signals via the transmission medium, receive power via the transmission medium to power devices coupled to the second coupler, process and send data via the transmission medium, or any combination thereof. |
| FILED | Wednesday, February 25, 2009 |
| APPL NO | 12/392734 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/705 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422197 | Yaniv et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zvi Yaniv (Austin, Texas); Nan Jiang (Austin, Texas); James P. Novak (Austin, Texas); Richard L. Fink (Austin, Texas) |
| ASSIGNEE(S) | Applied Nanotech Holdings, Inc. (Austin, Texas) |
| INVENTOR(S) | Zvi Yaniv (Austin, Texas); Nan Jiang (Austin, Texas); James P. Novak (Austin, Texas); Richard L. Fink (Austin, Texas) |
| ABSTRACT | The instant article of manufacture is made by applying optical energy to one or more layers of nanoparticulate materials under predetermined conditions to produce a nanostructure. The nanostructure has layers of optically fused nanoparticles including a predetermined pore density, a predetermined pore size, or both. The predetermined conditions for applying the optical energy may include a predetermined voltage, a predetermined duration, a predetermined power density, or combinations thereof. |
| FILED | Wednesday, July 14, 2010 |
| APPL NO | 12/836547 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/502 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422285 | Apalkov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dmytro Apalkov (San Jose, California); Xueti Tang (Fremont, California); Vladimir Nikitin (Campbell, California); Alexander A. G. Driskill-Smith (Redwood City, California); Steven M. Watts (Mountain View, California); David Druist (Santa Clara, California) |
| ASSIGNEE(S) | Grandis, Inc. (San Jose, California) |
| INVENTOR(S) | Dmytro Apalkov (San Jose, California); Xueti Tang (Fremont, California); Vladimir Nikitin (Campbell, California); Alexander A. G. Driskill-Smith (Redwood City, California); Steven M. Watts (Mountain View, California); David Druist (Santa Clara, California) |
| ABSTRACT | A method and system for providing a magnetic junction usable in a magnetic memory are described. The magnetic junction includes first and second pinned layers, first and second nonmagnetic spacer layers, and a free layer. The pinned layers are nonmagnetic layer-free and self-pinned. In some aspects, the magnetic junction is configured to allow the free and second pinned layers to be switched between stable magnetic states when write currents are passed therethrough. The magnetic junction has greater than two stable states. In other aspects, the magnetic junction includes at least third and fourth spacer layers, a second free layer therebetween, and a third pinned layer having a pinned layer magnetic moment, being nonmagnetic layer-free, and being coupled to the second pinned layer. The magnetic junction is configured to allow the free layers to be switched between stable magnetic states when write currents are passed therethrough. |
| FILED | Wednesday, February 23, 2011 |
| APPL NO | 13/033021 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/171 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422311 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marion Joseph Roberts (Ridgecrest, California); Timothy Mark Ochoa (Ridgecrest, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marion Joseph Roberts (Ridgecrest, California); Timothy Mark Ochoa (Ridgecrest, California) |
| ABSTRACT | A EPROM erasing apparatus and method for erasing an EPROM(s). The EPROM(s) is erased using light emitted from an ultraviolet light emitting diode. |
| FILED | Friday, July 30, 2010 |
| APPL NO | 12/847184 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/185.290 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422473 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ana M. Cheng (Odessa, Florida); Norbert J. Riviere (Seminole, Florida) |
| ASSIGNEE(S) | Science Applications International Corporation (San Diego, California) |
| INVENTOR(S) | Ana M. Cheng (Odessa, Florida); Norbert J. Riviere (Seminole, Florida) |
| ABSTRACT | The invention provides a set of mechanisms by which a wireless mobile mesh node equipped with a directional antenna may self form and self adapt its steady-state communications schedule. A link establishment handshake is carried out over an ongoing subtemplate-based discovery scan. During time not reserved for steady-state communications with previously discovered neighbors, nodes continue to search for an establish links with new neighbors. Initial and subsequent bandwidth allocation protocols may be utilized to allow peer nodes to coordinate communication opportunities between the peer nodes without impacting or having knowledge about reservations for communications with other peers. The link establishment and initial bandwidth allocation protocols may be piggy-backed for readily establishing an initial steady-state schedule with a peer upon link establishment without impact on previous steady state reservations by other nodes or on ongoing link establishment attempts elsewhere. |
| FILED | Thursday, September 15, 2011 |
| APPL NO | 13/233612 |
| ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Multiplex communications 370/338 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422681 | Gennaro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rosario Gennaro (New York, New York); Shai Halevi (New York, New York); Hugo M Krawczyk (Tarrytown, New York); Tal Rabin (Riverdale, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Rosario Gennaro (New York, New York); Shai Halevi (New York, New York); Hugo M Krawczyk (Tarrytown, New York); Tal Rabin (Riverdale, New York) |
| ABSTRACT | A pairwise key-agreement scheme is provided for creating key agreements non-interactively between pairs of nodes disposed in a hierarchy of nodes. The scheme is non-interactive so that any two nodes can agree on a shared secret key without interaction. In addition, the scheme is identity-based so that any given node only needs to know the identity of peer nodes to compute the shared secret key. All of the nodes are arranged in a hierarchy where an intermediate node in the hierarchy can derive the secret keys for each of its children from its own secret key and the identity of the child. Accordingly, the scheme is fully resilient against compromise of any number of leaves in the hierarchy and of a threshold number of nodes in the upper levels of the hierarchy. The scheme is well-suited for environments such as mobile ad-hoc networks (MANETs), which are very dynamic, have acute bandwidth-constraints and have many nodes are vulnerable to compromise. |
| FILED | Thursday, March 06, 2008 |
| APPL NO | 12/043755 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Cryptography 380/277 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422683 | Sniffen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian T Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Brian T Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
| ABSTRACT | A system, method, and computer program product are provided for requesting a proof of a security policy in a client system. Additionally, a system, method, and computer program product are provided for proving a security policy to an interrogator system. |
| FILED | Tuesday, July 15, 2008 |
| APPL NO | 12/173229 |
| ART UNIT | 2453 — Computer Networks |
| CURRENT CPC | Cryptography 380/277 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422738 | Stastny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John C. Stastny (San Diego, California); Michael R. Hughes (San Diego, California); Keith Pifko (Philadelphia, Pennsylvania); Daniel Garcia (San Diego, California); Bryan Bagnall (San Diego, California); Heidi Buck (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John C. Stastny (San Diego, California); Michael R. Hughes (San Diego, California); Keith Pifko (Philadelphia, Pennsylvania); Daniel Garcia (San Diego, California); Bryan Bagnall (San Diego, California); Heidi Buck (San Diego, California) |
| ABSTRACT | A method involves adapting a vessel detection algorithm based upon received synthetic aperture radar (SAR) image data and associated metadata, detecting one or more vessels within an image tile of the SAR image data by iteratively applying the adapted vessel detection algorithm to successive portions of the image tile, discarding a detected vessel if a false alarm is determined, extracting one or more features from the detected vessels that are not discarded, and generating one or more output products based upon the extracted features. |
| FILED | Wednesday, February 23, 2011 |
| APPL NO | 13/032712 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422951 | Nejad et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shah A. Nejad (Colorado Spring, Colorado); Rafael A. Ihly (Vail, Arizona); Chad Wangsvick (Arvada, Colorado) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Shah A. Nejad (Colorado Spring, Colorado); Rafael A. Ihly (Vail, Arizona); Chad Wangsvick (Arvada, Colorado) |
| ABSTRACT | Systems and methods for wireless signal communication in flight vehicles are disclosed. In an embodiment, a system includes a first portion that generates a first wireless zone. A second portion is decoupleable from the first portion and generates a second wireless zone. The first wireless zone and the second wireless zone communicate flight-related information while the first portion and the second portion are coupled, and discontinue the communication subsequent to the separation of the first portion from the second structural portion. In another embodiment, a method includes establishing a first wireless zone in a first portion of a flight vehicle, and establishing a second wireless zone in a second decoupleable portion of the flight vehicle. Flight-related information is communicated between the first wireless zone and the second wireless zone while the first portion and the second portion are coupled, and communication is discontinued after decoupling. |
| FILED | Thursday, January 28, 2010 |
| APPL NO | 12/695322 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/41.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423336 | Bennett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John O. Bennett (Linton, Indiana); Brent A. Waggoner (Sandborn, Indiana); James T. Sweeten (Vincennes, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John O. Bennett (Linton, Indiana); Brent A. Waggoner (Sandborn, Indiana); James T. Sweeten (Vincennes, Indiana) |
| ABSTRACT | A system and method implemented on a computing device are provided to simulate trajectories of objects dispensed from a moving aircraft. |
| FILED | Wednesday, December 16, 2009 |
| APPL NO | 12/639620 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423487 | Rubin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stuart H. Rubin (San Diego, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stuart H. Rubin (San Diego, California) |
| ABSTRACT | Sea characteristics are determined by using a buoy with multiple tilt switches configured to sense at plural tilt angles of the buoy. The tilt switches provide binary outputs of tilt data corresponding to the tilt angles. The binary outputs are received by a processor and are compared with sample patterns of tilt data. The comparison is used to provide an output corresponding to sea conditions. |
| FILED | Wednesday, August 11, 2010 |
| APPL NO | 12/854602 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423492 | Hodgin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles Reed Hodgin (Westminster, Colorado) |
| ASSIGNEE(S) | AlphaTRAC, Inc. (Westminster, Colorado) |
| INVENTOR(S) | Charles Reed Hodgin (Westminster, Colorado) |
| ABSTRACT | A system and method that provide for decision support and/or training support in crisis decision-making situations are provided. In one implementation, for example, a method identifies patterns from known cases based on information from a crisis event. Each of the known cases includes attributes and at least one outcome. The method also identifies a first subset of the known cases that relate to the identified patterns from the known cases. The method also analyzes the identified patterns to determine a cue that, if answered, will provide a second subset of the known cases including a more converged range of decision outcomes than the first subset. |
| FILED | Tuesday, January 12, 2010 |
| APPL NO | 12/686301 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423966 | Dolby et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Julian Dolby (Bronx, New York); Frank Tip (Ridgewood, New Jersey); Mandana Vaziri (White Plains, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Julian Dolby (Bronx, New York); Frank Tip (Ridgewood, New Jersey); Mandana Vaziri (White Plains, New York) |
| ABSTRACT | A system and method for ensuring consistency of data and preventing data races, including steps of: receiving and examining a computer program written in an object-oriented language; receiving sequences of accesses that form logical operations on a set of memory locations used by the program; receiving definitions of atomic sets of data from the memory locations, wherein said atomic sets are sets of data that indicate an existence of a consistency property without requiring the consistency property itself; inferring which code blocks of the computer program must be synchronized in order to prevent one or more data races in the computer program, wherein synchronization is inferred by determining by analysis for each unit of work, what atomic sets are read and written by the unit of work; and providing a message indicating where synchronization is required. |
| FILED | Monday, April 05, 2010 |
| APPL NO | 12/754012 |
| ART UNIT | 2198 — Multiplex and VoIP |
| CURRENT CPC | Data processing: Software development, installation, and management 717/126 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08424003 | Degenaro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Louis R. Degenaro (White Plains, New York); James R. Challenger (Garrison, New York); James R. Giles (Yorktown Heights, New York); Paul Reed (Brookline, Massachusetts); Rohit Wagle (Elmsford, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Louis R. Degenaro (White Plains, New York); James R. Challenger (Garrison, New York); James R. Giles (Yorktown Heights, New York); Paul Reed (Brookline, Massachusetts); Rohit Wagle (Elmsford, New York) |
| ABSTRACT | Methods and systems are provided for unified job processing of interdependent heterogeneous tasks within a domain containing a plurality of nodes. Jobs containing components to be processed in the domain are submitted and are identified by type. A job control flow associated with the job type is identified and used to process the components of the job on various nodes within the domain. Multiple job control flows are handled simultaneously, and provisions are made for sharing common job components among jobs. The job control flow utilizes a finite state machine where a given instance of the finite state machine applies to a specific job type. The finite state machine can be expressed using extensible mark-up language schema. |
| FILED | Wednesday, May 31, 2006 |
| APPL NO | 11/444129 |
| ART UNIT | 2195 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08418457 | Schmidt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Darren D. Schmidt (Thompson, North Dakota) |
| ASSIGNEE(S) | Energy and Enviromental Research Center Foundation (Grand Forks, North Dakota) |
| INVENTOR(S) | Darren D. Schmidt (Thompson, North Dakota) |
| ABSTRACT | A system for controlling the emission of associated gas produced from a reservoir. In an embodiment, the system comprises a gas compressor including a gas inlet in fluid communication with an associated gas source and a gas outlet. The gas compressor adjusts the pressure of the associated gas to produce a pressure-regulated associated gas. In addition, the system comprises a gas cleaner including a gas inlet in fluid communication with the outlet of the gas compressor, a fuel gas outlet, and a waste product outlet. The gas cleaner separates at least a portion of the sulfur and the water from the associated gas to produce a fuel gas. Further, the system comprises a gas turbine including a fuel gas inlet in fluid communication with the fuel gas outlet of the gas cleaner and an air inlet. Still further, the system comprises a choke in fluid communication with the air inlet. |
| FILED | Friday, August 01, 2008 |
| APPL NO | 12/184860 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Power plants 060/597 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418686 | Liao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Henry H. Liao (Los Alamitos, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Henry H. Liao (Los Alamitos, California) |
| ABSTRACT | A tracker including an outer post having elongated bore, and a lower end mounted on a sub-structure, an inner pole rotatably received in the elongated bore, a lower bearing in the bore adjacent a lower end of the outer post and attached thereto to be constrained from lateral movement and mounted on the sub-structure such that a lower end of the inner pole rests on and is supported by the lower bearing, an upper bearing near an upper end of the outer post, a circumferential drive supported on the outer post for rotating the inner pole relative to the outer post, such that substantially a full weight of a load on the inner pole is directly transmitted to the sub-structure and lateral force and torque leverage are placed on a full length of the outer post by way of the upper and lower bearing. |
| FILED | Friday, June 19, 2009 |
| APPL NO | 12/488098 |
| ART UNIT | 3743 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Stoves and furnaces 126/571 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08418760 | Decker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David L. Decker (Reno, Nevada); Brad F. Lyles (Reno, Nevada); Richard G. Purcell (Reno, Nevada); Ronald Lee Hershey (Reno, Nevada) |
| ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education, on behalf of the Desert Research Institute (Reno, Nevada) |
| INVENTOR(S) | David L. Decker (Reno, Nevada); Brad F. Lyles (Reno, Nevada); Richard G. Purcell (Reno, Nevada); Ronald Lee Hershey (Reno, Nevada) |
| ABSTRACT | The present disclosure provides an apparatus and method for coupling conduit segments together. A first pump obtains a sample and transmits it through a first conduit to a reservoir accessible by a second pump. The second pump further conducts the sample from the reservoir through a second conduit. |
| FILED | Tuesday, February 16, 2010 |
| APPL NO | 12/706670 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Wells 166/264 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419356 | Little |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David A. Little (Chuluota, Florida) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | David A. Little (Chuluota, Florida) |
| ABSTRACT | A seal assembly that limits gas leakage from a hot gas path to one or more disc cavities in a turbine engine. The seal assembly includes a seal apparatus that limits gas leakage from the hot gas path to a respective one of the disc cavities. The seal apparatus comprises a plurality of blade members rotatable with a blade structure. The blade members are associated with the blade structure and extend toward adjacent stationary components. Each blade member includes a leading edge and a trailing edge, the leading edge of each blade member being located circumferentially in front of the blade member's corresponding trailing edge in a direction of rotation of the turbine rotor. The blade members are arranged such that a space having a component in a circumferential direction is defined between adjacent circumferentially spaced blade members. |
| FILED | Wednesday, April 01, 2009 |
| APPL NO | 12/416423 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/173.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419827 | Repasky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Michael Repasky (Allentown, Pennsylvania); Michael Francis Carolan (Allentown, Pennsylvania); VanEric Edward Stein (Allentown, Pennsylvania); Christopher Ming-Poh Chen (Allentown, Pennsylvania) |
| ASSIGNEE(S) | Air Products and Chemicals, Inc. (Allentown, Pennsylvania) |
| INVENTOR(S) | John Michael Repasky (Allentown, Pennsylvania); Michael Francis Carolan (Allentown, Pennsylvania); VanEric Edward Stein (Allentown, Pennsylvania); Christopher Ming-Poh Chen (Allentown, Pennsylvania) |
| ABSTRACT | Ion transport membrane oxidation system comprising (a) two or more membrane oxidation stages, each stage comprising a reactant zone, an oxidant zone, one or more ion transport membranes separating the reactant zone from the oxidant zone, a reactant gas inlet region, a reactant gas outlet region, an oxidant gas inlet region, and an oxidant gas outlet region; (b) an interstage reactant gas flow path disposed between each pair of membrane oxidation stages and adapted to place the reactant gas outlet region of a first stage of the pair in flow communication with the reactant gas inlet region of a second stage of the pair; and (c) one or more reactant interstage feed gas lines, each line being in flow communication with any interstage reactant gas flow path or with the reactant zone of any membrane oxidation stage receiving interstage reactant gas. |
| FILED | Monday, July 16, 2012 |
| APPL NO | 13/549900 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Gas separation: Processes 095/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419974 | Comanzo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Holly Ann Comanzo (Niskayuna, New York); Mohan Manoharan (Niskayuna, New York); Sergio Paulo Martins Loureiro (Saratoga Springs, New York); Anant Achyut Setlur (Niskayuna, New York); Alok Mani Srivastava (Niskayuna, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Holly Ann Comanzo (Niskayuna, New York); Mohan Manoharan (Niskayuna, New York); Sergio Paulo Martins Loureiro (Saratoga Springs, New York); Anant Achyut Setlur (Niskayuna, New York); Alok Mani Srivastava (Niskayuna, New York) |
| ABSTRACT | Disclosed here are methods for the preparation of optionally activated nanocrystalline rare earth phosphates. The optionally activated nanocrystalline rare earth phosphates may be used as one or more of quantum-splitting phosphor, visible-light emitting phosphor, vacuum-UV absorbing phosphor, and UV-emitting phosphor. Also disclosed herein are discharge lamps comprising the optionally activated nanocrystalline rare earth phosphates provided by these methods. |
| FILED | Thursday, December 11, 2008 |
| APPL NO | 12/332881 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compositions 252/301.4P0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419998 | Luhrs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Claudia C. Luhrs (Rio Rancho, New Mexico); Jonathan Phillips (Rio Rancho, New Mexico); Monique N. Richard (Ann Arbor, Michigan); Angela Michelle Knapp (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Toyota Motor Engineering and Manufacturing North America, Inc. (Erlanger, Kentucky); The Regents of the University of New Mexico (Albuquerque, New Mexico); Los Alamos National Lab (Los Alamos, New Mexico) |
| INVENTOR(S) | Claudia C. Luhrs (Rio Rancho, New Mexico); Jonathan Phillips (Rio Rancho, New Mexico); Monique N. Richard (Ann Arbor, Michigan); Angela Michelle Knapp (Ann Arbor, Michigan) |
| ABSTRACT | A hollow carbon sphere having a carbon shell and an inner core is disclosed. The hollow carbon sphere has a total volume that is equal to a volume of the carbon shell plus an inner free volume within the carbon shell. The inner free volume is at least 25% of the total volume. In some instances, a nominal diameter of the hollow carbon sphere is between 10 and 180 nanometers. |
| FILED | Wednesday, April 06, 2011 |
| APPL NO | 13/080738 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/483 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420032 | Ermanoski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ivan Ermanoski (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Ivan Ermanoski (Albuquerque, New Mexico) |
| ABSTRACT | Reactors and methods for solar thermochemical reactions are disclosed. Embodiments of reactors include at least two distinct reactor chambers between which there is at least a pressure differential. In embodiments, reactive particles are exchanged between chambers during a reaction cycle to thermally reduce the particles at first conditions and oxidize the particles at second conditions to produce chemical work from heat. In embodiments, chambers of a reactor are coupled to a heat exchanger to pre-heat the reactive particles prior to direct exposure to thermal energy with heat transferred from reduced reactive particles as the particles are oppositely conveyed between the thermal reduction chamber and the fuel production chamber. In an embodiment, particle conveyance is in part provided by an elevator which may further function as a heat exchanger. |
| FILED | Monday, August 29, 2011 |
| APPL NO | 13/220321 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/630 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420271 | Choi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tayoung Choi (Rochester, New York); Sriram Ganapathy (Rochester, New York); Jaehak Jung (Pittsford, New York); David R. Savage (Webster, New York); Balasubramanian Lakshmanan (Pittsford, New York); Pamela M. Vecasey (Honeoye Falls, New York) |
| ASSIGNEE(S) | GM GLobal Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Tayoung Choi (Rochester, New York); Sriram Ganapathy (Rochester, New York); Jaehak Jung (Pittsford, New York); David R. Savage (Webster, New York); Balasubramanian Lakshmanan (Pittsford, New York); Pamela M. Vecasey (Honeoye Falls, New York) |
| ABSTRACT | A system and method for detecting a low performing cell in a fuel cell stack using measured cell voltages. The method includes determining that the fuel cell stack is running, the stack coolant temperature is above a certain temperature and the stack current density is within a relatively low power range. The method further includes calculating the average cell voltage, and determining whether the difference between the average cell voltage and the minimum cell voltage is greater than a predetermined threshold. If the difference between the average cell voltage and the minimum cell voltage is greater than the predetermined threshold and the minimum cell voltage is less than another predetermined threshold, then the method increments a low performing cell timer. A ratio of the low performing cell timer and a system run timer is calculated to identify a low performing cell. |
| FILED | Tuesday, July 14, 2009 |
| APPL NO | 12/502961 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/432 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420278 | De Rose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anthony J. De Rose (Rochester, New York); Subhasish Mukerjee (Pittsford, New York); Karl Jacob Haltiner, Jr. (Fairport, New York) |
| ASSIGNEE(S) | Delphi Technologies, Inc. (Troy, Michigan) |
| INVENTOR(S) | Anthony J. De Rose (Rochester, New York); Subhasish Mukerjee (Pittsford, New York); Karl Jacob Haltiner, Jr. (Fairport, New York) |
| ABSTRACT | A solid oxide fuel cell stack having a plurality of cassettes and a glass composite seal disposed between the sealing surfaces of adjacent cassettes, thereby joining the cassettes and providing a hermetic seal therebetween. The glass composite seal includes an alkaline earth aluminosilicate (AEAS) glass disposed about a viscous glass such that the AEAS glass retains the viscous glass in a predetermined position between the first and second sealing surfaces. The AEAS glass provides geometric stability to the glass composite seal to maintain the proper distance between the adjacent cassettes while the viscous glass provides for a compliant and self-healing seal. The glass composite seal may include fibers, powders, and/or beads of zirconium oxide, aluminum oxide, yttria-stabilized zirconia (YSZ), or mixtures thereof, to enhance the desirable properties of the glass composite seal. |
| FILED | Thursday, December 30, 2010 |
| APPL NO | 12/981881 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/510 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420351 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lan Tang (Beijing, China PRC); Ye Liu (Beijing, China PRC); Junxin Duan (Beijing, China PRC); Yu Zhang (Beijing, China PRC); Christian Isak Jorgensen (Bagsvaerd, Denmark); Randall Kramer (Lincoln, California) |
| ASSIGNEE(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Lan Tang (Beijing, China PRC); Ye Liu (Beijing, China PRC); Junxin Duan (Beijing, China PRC); Yu Zhang (Beijing, China PRC); Christian Isak Jorgensen (Bagsvaerd, Denmark); Randall Kramer (Lincoln, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Friday, July 13, 2012 |
| APPL NO | 13/548726 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420364 | Alvizo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oscar Alvizo (Fremont, California); Mike Benoit (Denver, Colorado); Scott Novick (Palo Alto, California) |
| ASSIGNEE(S) | Codexis, Inc. (Redwood City, California) |
| INVENTOR(S) | Oscar Alvizo (Fremont, California); Mike Benoit (Denver, Colorado); Scott Novick (Palo Alto, California) |
| ABSTRACT | The present disclosure relates to β-class carbonic anhydrase polypeptides having improved properties including increased thermostability and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides formulations and uses of the polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering. Also provided are polynucleotides encoding the carbonic anhydrase polypeptides and host cells capable of expressing them. |
| FILED | Thursday, June 30, 2011 |
| APPL NO | 13/174393 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420390 | Waldo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Geoffrey S. Waldo (Santa Fe, New Mexico); Stephanie Cabantous (Los Alamos, New Mexico) |
| ABSTRACT | Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The invention further provides various nucleic acid molecules and vectors incorporating such nucleic acid molecules, comprising polynucleotides encoding fluorescent protein circular permutants derived from superfolder GFP, which polynucleotides include an internal cloning site into which a heterologous polynucleotide may be inserted in-frame with the circular permutant coding sequence, and which when expressed are capable of reporting on the degree to which a polypeptide encoded by such an inserted heterologous polynucleotide is correctly folded by correlation with the degree of fluorescence exhibited. |
| FILED | Friday, October 12, 2012 |
| APPL NO | 13/651211 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420607 | Carlson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Russell W. Carlson (Athens, Georgia); Geert-Jan Boons (Athens, Georgia); Conrad Quinn (Lilburn, Georgia); Mahalakshmi Vasan (Athens, Georgia); Margreet A. Wolfert (Athens, Georgia); Biswa Choudhury (Athens, Georgia); Elmar Kannenberg (Athens, Georgia); Christine Leoff (Athens, Georgia); Alok Mehta (Athens, Georgia); Elke Saile (Athens, Georgia); Jana Rauvolfova (Braselton, Georgia); Patricia Wilkins (Duluth, Georgia); Alex J. Harvey (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Russell W. Carlson (Athens, Georgia); Geert-Jan Boons (Athens, Georgia); Conrad Quinn (Lilburn, Georgia); Mahalakshmi Vasan (Athens, Georgia); Margreet A. Wolfert (Athens, Georgia); Therese Buskas (Athens, Georgia); Biswa Choudhury (Athens, Georgia); Elmar Kannenberg (Athens, Georgia); Christine Leoff (Athens, Georgia); Alok Mehta (Athens, Georgia); Elke Saile (Athens, Georgia); Jana Rauvolfova (Braselton, Georgia); Patricia Wilkins (Duluth, Georgia) |
| ABSTRACT | The present invention presents the isolation, characterization and synthesis of oligosaccharides of Bacillus anthracis. Also presented are antibodies that bind to such saccharide moieties and various methods of use for such saccharide moieties and antibodies. |
| FILED | Wednesday, December 24, 2008 |
| APPL NO | 12/317693 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420704 | Hillmyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marc Hillmyer (Minneapolis, Minnesota); Liang Chen (Berkeley, California) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Saint Paul, Minnesota) |
| INVENTOR(S) | Marc Hillmyer (Minneapolis, Minnesota); Liang Chen (Berkeley, California) |
| ABSTRACT | A process for preparing a polymer composite that includes reacting (a) a multi-functional monomer and (b) a block copolymer comprising (i) a first block and (ii) a second block that includes a functional group capable of reacting with the multi-functional monomer, to form a crosslinked, nano-structured, bi-continuous composite. The composite includes a continuous matrix phase and a second continuous phase comprising the first block of the block copolymer. |
| FILED | Friday, July 18, 2008 |
| APPL NO | 12/669857 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420794 | Bradbury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew M. Bradbury (Santa Fe, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Andrew M. Bradbury (Santa Fe, New Mexico) |
| ABSTRACT | Humanized recombinant and monoclonal antibodies specific for the ectodomain of the influenza virus M2 ion channel protein are disclosed. The antibodies of the invention have anti-viral activity and may be useful as anti-viral therapeutics and/or prophylactic/vaccine agents for inhibiting influenza virus replication and for treating individuals infected with influenza. |
| FILED | Tuesday, November 15, 2011 |
| APPL NO | 13/296414 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420815 | Gakh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andrei A. Gakh (Bethesda, Maryland); Mikhail Krasavin (Moscow, Russian Federation); Ruben Karapetian (Moscow, Russian Federation); Konstantin A. Rufanov (Moscow, Russian Federation); Igor Konstantinov (Moscow, Russian Federation); Elena Godovykh (Rostov-Na-Donu, Russian Federation); Olga Soldatkina (Moscow, Russian Federation); Andrey V. Sosnov (Moscow, Russian Federation) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Andrei A. Gakh (Bethesda, Maryland); Mikhail Krasavin (Moscow, Russian Federation); Ruben Karapetian (Moscow, Russian Federation); Konstantin A. Rufanov (Moscow, Russian Federation); Igor Konstantinov (Moscow, Russian Federation); Elena Godovykh (Rostov-Na-Donu, Russian Federation); Olga Soldatkina (Moscow, Russian Federation); Andrey V. Sosnov (Moscow, Russian Federation) |
| ABSTRACT | The present disclosure relates to novel compounds that can be used as anti-cancer agents in the prostate cancer therapy. In particular, the invention relates to N-acyl derivatives of 2,3-dihydro-1H-pyrrolo[2,3-b]quinolines having the structural Formula (I), stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or pharmaceutically acceptable salt and/or solvate thereof. The meaning of R1 is independently selected from H; C1-C6 Alkyl, cyclo-Alkyl or iso-Alkyl substituents; R2 is selected from C1-C6 Alkyl, cyclo-Alkyl or iso-Alkyl; substituted or non-substituted, fused or non-fused to substituted or non-substituted aromatic ring, aryl or heteroaryl groups. The invention also relates to methods for preparing said compounds, and to pharmaceutical compositions comprising said compounds. |
| FILED | Thursday, June 24, 2010 |
| APPL NO | 12/822237 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420833 | Katz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a non-naturally occurring polyketide synthase (PKS) capable of synthesizing a carboxylic acid or a lactone, and a composition such that a carboxylic acid or lactone is included. The carboxylic acid or lactone, or derivative thereof, is useful as a biofuel. The present invention also provides for a recombinant nucleic acid or vector that encodes such a PKS, and host cells which also have such a recombinant nucleic acid or vector. The present invention also provides for a method of producing such carboxylic acids or lactones using such a PKS. |
| FILED | Wednesday, April 29, 2009 |
| APPL NO | 12/921463 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/273 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420890 | Gan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Susheng Gan (Ithaca, New York); Yongfeng Guo (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Susheng Gan (Ithaca, New York); Yongfeng Guo (Ann Arbor, Michigan) |
| ABSTRACT | The present invention discloses transgenic plants having an altered level of NAP protein compared to that of a non-transgenic plant, where the transgenic plants display an altered leaf senescence phenotype relative to a non-transgenic plant, as well as mutant plants comprising an inactivated NAP gene, where mutant plants display a delayed leaf senescence phenotype compared to that of a non-mutant plant. The present invention also discloses methods for delaying leaf senescence in a plant, as well as methods of making a mutant plant having a decreased level of NAP protein compared to that of a non-mutant plant, where the mutant plant displays a delayed leaf senescence phenotype relative to a non-mutant plant. Methods for causing precocious leaf senescence or promoting leaf senescence in a plant are also disclosed. Also disclosed are methods of identifying a candidate plant suitable for breeding that displays a delayed leaf senescence and/or enhanced yield phenotype. |
| FILED | Wednesday, March 28, 2007 |
| APPL NO | 12/294593 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420928 | Polcyn |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Adam D. Polcyn (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Adam D. Polcyn (Pittsburgh, Pennsylvania) |
| ABSTRACT | A device for recovering waste heat in the form of radiated light, e.g. red visible light and/or infrared light includes a housing having a viewing window, and a photovoltaic cell mounted in the housing in a relationship to the viewing window, wherein rays of radiated light pass through the viewing window and impinge on surface of the photovoltaic cell. The housing and/or the cell are cooled so that the device can be used with a furnace for an industrial process, e.g. mounting the device with a view of the interior of the heating chamber of a glass making furnace. In this manner, the rays of the radiated light generated during the melting of glass batch materials in the heating chamber pass through the viewing window and impinge on the surface of the photovoltaic cells to generate electric current which is passed onto an electric load. |
| FILED | Thursday, February 14, 2008 |
| APPL NO | 12/031303 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/259 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422402 | Archer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles J. Archer (Rochester, Minnesota); Ahmad A. Faraj (Rochester, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Ahmad A. Faraj (Rochester, Texas) |
| ABSTRACT | Methods, systems, and products are disclosed for broadcasting a message in a parallel computer that includes: transmitting, by the logical root to all of the nodes directly connected to the logical root, a message; and for each node except the logical root: receiving the message; if that node is the physical root, then transmitting the message to all of the child nodes except the child node from which the message was received; if that node received the message from a parent node and if that node is not a leaf node, then transmitting the message to all of the child nodes; and if that node received the message from a child node and if that node is not the physical root, then transmitting the message to all of the child nodes except the child node from which the message was received and transmitting the message to the parent node. |
| FILED | Tuesday, April 01, 2008 |
| APPL NO | 12/060492 |
| ART UNIT | 2475 — Semiconductors/Memory |
| CURRENT CPC | Multiplex communications 370/256 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423663 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles J. Archer (Rochester, Minnesota); Ahmad A. Faraj (Rochester, Minnesota); Todd A. Inglett (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Ahmad A. Faraj (Rochester, Minnesota); Todd A. Inglett (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota) |
| ABSTRACT | Methods, apparatus, and products are disclosed for providing full point-to-point communications among compute nodes of an operational group in a global combining network of a parallel computer, each compute node connected to each adjacent compute node in the global combining network through a link, that include: receiving a network packet in a compute node, the network packet specifying a destination compute node; selecting, in dependence upon the destination compute node, at least one of the links for the compute node along which to forward the network packet toward the destination compute node; and forwarding the network packet along the selected link to the adjacent compute node connected to the compute node through the selected link. |
| FILED | Monday, August 06, 2007 |
| APPL NO | 11/834159 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/238 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423983 | Gschwind |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael K. Gschwind (Chappaqua, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael K. Gschwind (Chappaqua, New York) |
| ABSTRACT | Mechanisms for generating and executing programs for a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA) are provided. A computer program product comprising a computer recordable medium having a computer readable program recorded thereon is provided. The computer readable program, when executed on a computing device, causes the computing device to receive one or more instructions and execute the one or more instructions using logic in an execution unit of the computing device. The logic implements a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA), based on data stored in a vector register file of the computing device. The vector register file is configured to store both scalar and floating point values as vectors having a plurality of vector elements. |
| FILED | Tuesday, October 14, 2008 |
| APPL NO | 12/250581 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/151 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08423987 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles Jens Archer (Rochester, Minnesota); Amanda Peters (Rochester, Minnesota); Kurt Walter Pinnow (Rochester, Minnesota); Brent Allen Swartz (Chippewa Falls, Wisconsin) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles Jens Archer (Rochester, Minnesota); Amanda Peters (Rochester, Minnesota); Kurt Walter Pinnow (Rochester, Minnesota); Brent Allen Swartz (Chippewa Falls, Wisconsin) |
| ABSTRACT | An apparatus, program product and method optimize the operation of a massively parallel computer system by, in part, receiving actual performance data concerning an application executed by the plurality of interconnected nodes, and analyzing the actual performance data to identify an actual performance pattern. A desired performance pattern may be determined for the application, and an algorithm may be selected from among a plurality of algorithms stored within a memory, the algorithm being configured to achieve the desired performance pattern based on the actual performance data. |
| FILED | Tuesday, January 30, 2007 |
| APPL NO | 11/668691 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08418547 | Kysar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey William Kysar (New York, New York); James C. Hone (New York, New York); Changgu Lee (New York, New York); Xiaoding Wei (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jeffrey William Kysar (New York, New York); James C. Hone (New York, New York); Changgu Lee (New York, New York); Xiaoding Wei (New York, New York) |
| ABSTRACT | Force, pressure, or stiffness measurement or calibration can be provided, such as by using a graphene or other sheet membrane, which can provide a specified number of monolayers suspended over a substantially circular well. In an example, the apparatus can include a substrate, including a substantially circular well. A deformable sheet membrane can be suspended over the well. The membrane can be configured to include a specified integer number of one or more monolayers. A storage medium can comprise accompanying information about the suspended membrane or the substrate that, with a deflection displacement response of the suspended membrane to an applied force or pressure, provides a measurement of the applied force or pressure. |
| FILED | Thursday, August 06, 2009 |
| APPL NO | 13/057701 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/159 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420033 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yinzhi Zhang (Hudson, Ohio); Qunhui Zhou (Hudson, Ohio); Sidney G. Nelson (Hudson, Ohio) |
| ASSIGNEE(S) | Albemarle Corporation (Baton Rouge, Louisiana) |
| INVENTOR(S) | Yinzhi Zhang (Hudson, Ohio); Qunhui Zhou (Hudson, Ohio); Sidney G. Nelson (Hudson, Ohio) |
| ABSTRACT | Mercury adsorbed from combustion gas by activated carbon can be sequestered in concrete containing air entraining admixtures. The activated carbon may be made by providing a carbon char made from anthracite or low-volatile bituminous coal that was devolatilized and carbonized in an oxygen-depleted environment and activating this char in the presence of steam to provide an activated carbon with an acid blue 80 index of less than about 30 milligrams per gram of carbon. The activated carbon may also be made by providing a carbon char that was devolatilized and carbonized in an oxygen-depleted environment and activating this char in the presence of oxygen to provide an activated carbon. The carbon may be injected into a combustion gas stream containing fly ash and mercury and may then be removed with fly ash from the gas stream. The resulting composition may be used as a partial substitute for cement in air-entrained concretes. |
| FILED | Friday, November 23, 2007 |
| APPL NO | 12/305720 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420124 | DeSimone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Durham, North Carolina); Benjamin W. Maynor (Durham, North Carolina); Larkin E. Euliss (Chapel Hill, North Carolina); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Durham, North Carolina); Benjamin W. Maynor (Durham, North Carolina); Larkin E. Euliss (Chapel Hill, North Carolina); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Friday, July 06, 2007 |
| APPL NO | 11/825469 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/499 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420325 | Loeb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence A. Loeb (Bellevue, Washington); Leroy Hood (Seattle, Washington); Motoshi Suzuki (Nogoya, Japan) |
| ASSIGNEE(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Lawrence A. Loeb (Bellevue, Washington); Leroy Hood (Seattle, Washington); Motoshi Suzuki (Nogoya, Japan) |
| ABSTRACT | The present invention provides a method for identifying a thermostable polymerase having altered fidelity. The method consists of generating a random population of polymerase mutants by mutating at least one amino acid residue of a thermostable polymerase and screening the population for one or more active polymerase mutants by genetic selection. For example, the invention provides a method for identifying a thermostable polymerase having altered fidelity by mutating at least one amino acid residue in an active site O-helix of a thermostable polymerase. The invention also provides thermostable polymerases and nucleic acids encoding thermostable polymerases having altered fidelity, for example, high fidelity polymerases and low fidelity polymerases. The invention additionally provides a method for identifying one or more mutations in a gene by amplifying the gene with a high fidelity polymerase. The invention further provides a method for accurately copying repetitive nucleotide sequences using a high fidelity polymerase mutant. The invention also provides a method for diagnosing a genetic disease using a high fidelity polymerase mutant. The invention further provides a method for randomly mutagenizing a gene by amplifying the gene using a low fidelity polymerase mutant. |
| FILED | Thursday, November 04, 2010 |
| APPL NO | 12/939798 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420362 | Crawford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ronald L. Crawford (Moscow, Idaho); Malcolm B. Burbank (Pullman, Washington); Thomas J. Weaver (Moscow, Idaho); Barbara C. Williams (Viola, Idaho) |
| ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Ronald L. Crawford (Moscow, Idaho); Malcolm B. Burbank (Pullman, Washington); Thomas J. Weaver (Moscow, Idaho); Barbara C. Williams (Viola, Idaho) |
| ABSTRACT | A method for increasing the concentration of calcium carbonate in a geomaterial that contains indigenous microorganisms capable of hydrolyzing urea to ammonia, which method includes enriching the geomaterial with a source of nutrients, adding urea to the geomaterial which is hydrolyzed to ammonia and which raises the pH of the geomaterial, and adding a source of calcium ions to the geomaterial. Carbonate ions obtained by the hydrolysis of the urea combine with calcium ions to form calcium carbonate. |
| FILED | Friday, May 28, 2010 |
| APPL NO | 12/802103 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/168 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420833 | Katz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a non-naturally occurring polyketide synthase (PKS) capable of synthesizing a carboxylic acid or a lactone, and a composition such that a carboxylic acid or lactone is included. The carboxylic acid or lactone, or derivative thereof, is useful as a biofuel. The present invention also provides for a recombinant nucleic acid or vector that encodes such a PKS, and host cells which also have such a recombinant nucleic acid or vector. The present invention also provides for a method of producing such carboxylic acids or lactones using such a PKS. |
| FILED | Wednesday, April 29, 2009 |
| APPL NO | 12/921463 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/273 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08419643 | Sarvazyan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Armen P. Sarvazyan (Lambertville, New Jersey); Alexej Tatarinov (Riga, Latvia); Vladimir Egorov (Princeton, New Jersey) |
| ASSIGNEE(S) | Artann Laboratories Inc. (Trenton, New Jersey) |
| INVENTOR(S) | Armen P. Sarvazyan (Lambertville, New Jersey); Alexej Tatarinov (Riga, Latvia); Vladimir Egorov (Princeton, New Jersey) |
| ABSTRACT | Methods and apparatus are disclosed for non-invasive bone evaluation based on a broadband ultrasonic transducer emitting a train of ultrasonic wave packets of multiple carrier frequencies ranging from about 50 kHz to about 2 MHz. Receiving broadband ultrasonic transducer accepts broadband ultrasonic signal propagated through the bone. Computer processor provides for data analysis and feature extraction allowing diagnostic evaluation of the bone, including comparing the features of the received signal to a database of known bone conditions. |
| FILED | Thursday, September 21, 2006 |
| APPL NO | 11/533871 |
| ART UNIT | 3737 — Semiconductors/Memory |
| CURRENT CPC | Surgery 6/449 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419883 | Day et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen W. Day (Dayton, Ohio); G. Scott Campbell (Dayton, Ohio); Danny E. Tilton (Dayton, Ohio); Frederick Stoll (West Chester, Ohio); Michael Sheppard (Dayton, Ohio); Robin Banerjee (Centerville, Ohio) |
| ASSIGNEE(S) | Milliken and Company (Spartanburg, South Carolina) |
| INVENTOR(S) | Stephen W. Day (Dayton, Ohio); G. Scott Campbell (Dayton, Ohio); Danny E. Tilton (Dayton, Ohio); Frederick Stoll (West Chester, Ohio); Michael Sheppard (Dayton, Ohio); Robin Banerjee (Centerville, Ohio) |
| ABSTRACT | A fiber reinforced core panel is formed from strips of plastics foam helically wound with layers of rovings to form webs which may extend in a wave pattern or may intersect transverse webs. Hollow tubes may replace foam strips. Axial rovings cooperate with overlying helically wound rovings to form a beam or a column. Wound roving patterns may vary along strips for structural efficiency. Wound strips may alternate with spaced strips, and spacers between the strips enhance web buckling strength. Continuously wound rovings between spaced strips permit folding to form panels with reinforced edges. Continuously wound strips are helically wrapped to form annular structures, and composite panels may combine both thermoset and thermoplastic resins. Continuously wound strips or strip sections may be continuously fed either longitudinally or laterally into molding apparatus which may receive skin materials to form reinforced composite panels. |
| FILED | Thursday, November 08, 2007 |
| APPL NO | 11/983317 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/264 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420582 | Richmond et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Chaffee Richmond (Huntsville, Alabama); Harry F. Schramm, Jr. (Winchester, Tennessee); Francis G. Defalco (Houston, Texas) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Robert Chaffee Richmond (Huntsville, Alabama); Harry F. Schramm, Jr. (Winchester, Tennessee); Francis G. Defalco (Houston, Texas) |
| ABSTRACT | A wear and/or friction reducing additive for a lubricating fluid in which the additive is a combination of a moderately hydrophilic single-phase compound and an anti-wear and/or anti-friction aqueous salt solution. The aqueous salt solution produces a coating on boundary layer surfaces. The lubricating fluid can be an emulsion-free hydrophobic oil, hydraulic fluid, antifreeze, or water. Preferably, the moderately hydrophilic single-phase compound is sulfonated castor oil and the aqueous salt solution additionally contains boric acid and zinc oxide. The emulsions produced by the aqueous salt solutions, the moderately hydrophilic single-phase compounds, or the combination thereof provide targeted boundary layer organizers that significantly enhance the anti-wear and/or anti-friction properties of the base lubricant by decreasing wear and/or friction of sliding and/or rolling surfaces at boundary layers. |
| FILED | Tuesday, February 15, 2011 |
| APPL NO | 13/027472 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Solid anti-friction devices, materials therefor, lubricant or separant compositions for moving solid surfaces, and miscellaneous mineral oil compositions 58/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420717 | Khabashesku et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Valery N. Khabashesku (Houston, Texas); Oleksandr Kuznetsov (Houston, Texas); Rui Lobo (Almada, Portugal) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Valery N. Khabashesku (Houston, Texas); Oleksandr Kuznetsov (Houston, Texas); Rui Lobo (Almada, Portugal) |
| ABSTRACT | A method of making a water soluble carbon nanostructure includes treating a fluorinated carbon nanostructure material with a polyol in the presence of a base. A water soluble carbon nanostructure comprises a fluorinated carbon nanostructure covalently bound to a polyol. Exemplary uses of water soluble carbon nanostructures include use in polymer composites, biosensors and drug delivery vehicles. |
| FILED | Wednesday, July 23, 2008 |
| APPL NO | 12/670068 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 523/468 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08418642 | Vosburgh |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederick Vosburgh (Durham, North Carolina) |
| ASSIGNEE(S) | iRobot Corporation (Bedford, Massachusetts) |
| INVENTOR(S) | Frederick Vosburgh (Durham, North Carolina) |
| ABSTRACT | An unmanned submersible vehicle for use in a body of liquid having a top surface and in air overlying the top surface includes a hull, an integral antenna, and an antenna positioning system. The hull has first and second opposed ends. The hull includes a first hull portion adjacent the first end and a second hull portion adjacent the second end. The antenna is disposed within the first hull portion and/or is mounted on the first hull portion. The antenna positioning system is configured to reorient the hull from a transit position to a signal position. When the hull is in the signal position: the first hull portion and the antenna are disposed above the second hull portion a greater vertical distance than when the hull is in the transit position; the first hull portion and the antenna are disposed above the top surface and in the air while at least the second hull portion remains submerged in the body of liquid; and the antenna is operative to emit signals through the air above the top surface and/or to receive signals through the air above the top surface. |
| FILED | Thursday, May 07, 2009 |
| APPL NO | 12/437181 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/312 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08419659 | Egorov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vladmir Egorov (Princeton, New Jersey); Heather van Raalte (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey) |
| ASSIGNEE(S) | Artann Laboratories (Trenton, New Jersey) |
| INVENTOR(S) | Vladmir Egorov (Princeton, New Jersey); Heather van Raalte (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey) |
| ABSTRACT | Methods for assessment of pelvic floor conditions based on tactile imaging are described. The vaginal wall is deformed before and after an interventional procedure using a transvaginal probe equipped with tactile pressure sensors and a motion tracking sensor. The vaginal wall coordinates and pressure patterns are obtained during the examination and used to build 3-D tactile image of the vagina and to calculate elasticity modulus profiles and spacing profiles along selected lines inside 3-D tactile image. The “before” and “after” profile values at specified locations are then compared to each other and to thresholds or profiles for normal conditions of vagina and its support structures. Methods of the invention may be used in estimating an improvement after an interventional procedure such as pelvic tissue regeneration, muscle repair or implantation of a supporting structure. |
| FILED | Wednesday, April 04, 2012 |
| APPL NO | 13/439165 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/591 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420680 | Liotta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dennis C. Liotta (Atlanta, Georgia); James P. Snyder (Atlanta, Georgia); Stephen F. Traynelis (Decatur, Georgia); Lawrence Wilson (Atlanta, Georgia); Cara Mosley (Atlanta, Georgia); Raymond J. Dingledine (Atlanta, Georgia); Yesim Altas Tahirovic (Decatur, Georgia); Scott J. Myers (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); NeurOp, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Dennis C. Liotta (Atlanta, Georgia); James P. Snyder (Atlanta, Georgia); Stephen F. Traynelis (Decatur, Georgia); Lawrence Wilson (Atlanta, Georgia); Cara Mosley (Atlanta, Georgia); Raymond J. Dingledine (Atlanta, Georgia); Yesim Altas Tahirovic (Decatur, Georgia); Scott J. Myers (Atlanta, Georgia) |
| ABSTRACT | Provided are compounds, pharmaceutical compositions and methods of treatment or prophylaxis of disorders associated with NMDA receptor activity, including neuropathic pain, stroke, traumatic brain injury, epilepsy, and related neurologic events or neurodegeneration. Compounds are of the general Formula I, or a pharmaceutically acceptable salt, ester, prodrug or derivative thereof are provided: wherein: each (L)k-Ar1 is a substituted or unsubstituted, mono or bicyclic aryl or heteroaryl; W is a bond, alkyl, or alkenyl; X is a bond, NR1 or O and each R1 and R2 is independently H, alkyl, alkenyl or aralkyl or R1 and R2 taken together form a 5-8 membered ring; R3−R6 are selected from certain specific substituents or a carbonyl; Y is a bond, O, S, SO, SO2, CH2, NH, N(alkyl), or NHC(═O); and Z is OH, NR6R7, NR8SO2(alkyl), NR8C(O)NR6R7, NR8C(O)O(alkyl), NR8-dihydrothiazole, or NR8-dihydroimidazole or wherein Z can fuse with Ar2 to form selected heterocycles. |
| FILED | Monday, June 30, 2008 |
| APPL NO | 12/165308 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/376 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08422632 | Fowler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian Fowler (San Mateo, California); Andrew May (San Francisco, California) |
| ASSIGNEE(S) | Fluidigm Corporation (South San Francisco, California) |
| INVENTOR(S) | Brian Fowler (San Mateo, California); Andrew May (San Francisco, California) |
| ABSTRACT | An integrated fluidic circuit includes a substrate layer and a first structure coupled to the substrate layer and including a plurality of channels. The first structure is configured to provide for flow of one or more materials through the plurality of channels. The integrated fluidic circuit also includes a second structure coupled to the substrate layer. The second structure includes a plurality of control channels configured to receive an actuation pressure. The integrated fluidic circuit is characterized by a thickness of less than 1.5 mm. |
| FILED | Friday, June 24, 2011 |
| APPL NO | 13/168041 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/79 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08418538 | Dazzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | A. Dazzi Dazzi (Les Ulis, France); Clotilde Policar (Paris, France); Kevin Kjoller (Santa Barbara, California); Michael Reading (Norwich, United Kingdom); Konstantin Vodopyanov (San Jose, California); Craig Prater (Santa Barbara, California) |
| ASSIGNEE(S) | Anasys Instruments Inc. (Santa Barbara, California) |
| INVENTOR(S) | A. Dazzi Dazzi (Les Ulis, France); Clotilde Policar (Paris, France); Kevin Kjoller (Santa Barbara, California); Michael Reading (Norwich, United Kingdom); Konstantin Vodopyanov (San Jose, California); Craig Prater (Santa Barbara, California) |
| ABSTRACT | An AFM based technique has been demonstrated for performing highly localized IR spectroscopy on a sample surface. Significant issues as to size, cost of implementation, and repeatability/robustness of results exist in commercializing the technique. The invention addresses many of these issues thereby producing a version of the analytical technique that can be made generally available to the scientific community. |
| FILED | Friday, November 04, 2011 |
| APPL NO | 13/289640 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08420123 | Troiano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Greg Troiano (Pembroke, Massachusetts); Michael Figa (Allston, Massachusetts); Abhimanyu Sabnis (Arlington, Massachusetts) |
| ASSIGNEE(S) | BIND Biosciences, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Greg Troiano (Pembroke, Massachusetts); Michael Figa (Allston, Massachusetts); Abhimanyu Sabnis (Arlington, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to methods of making nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. |
| FILED | Tuesday, June 16, 2009 |
| APPL NO | 12/485406 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08422683 | Sniffen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian T Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Brian T Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
| ABSTRACT | A system, method, and computer program product are provided for requesting a proof of a security policy in a client system. Additionally, a system, method, and computer program product are provided for proving a security policy to an interrogator system. |
| FILED | Tuesday, July 15, 2008 |
| APPL NO | 12/173229 |
| ART UNIT | 2453 — Computer Networks |
| CURRENT CPC | Cryptography 380/277 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08424003 | Degenaro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Louis R. Degenaro (White Plains, New York); James R. Challenger (Garrison, New York); James R. Giles (Yorktown Heights, New York); Paul Reed (Brookline, Massachusetts); Rohit Wagle (Elmsford, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Louis R. Degenaro (White Plains, New York); James R. Challenger (Garrison, New York); James R. Giles (Yorktown Heights, New York); Paul Reed (Brookline, Massachusetts); Rohit Wagle (Elmsford, New York) |
| ABSTRACT | Methods and systems are provided for unified job processing of interdependent heterogeneous tasks within a domain containing a plurality of nodes. Jobs containing components to be processed in the domain are submitted and are identified by type. A job control flow associated with the job type is identified and used to process the components of the job on various nodes within the domain. Multiple job control flows are handled simultaneously, and provisions are made for sharing common job components among jobs. The job control flow utilizes a finite state machine where a given instance of the finite state machine applies to a specific job type. The finite state machine can be expressed using extensible mark-up language schema. |
| FILED | Wednesday, May 31, 2006 |
| APPL NO | 11/444129 |
| ART UNIT | 2195 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Classified Government Agency
| US 08422799 | Witzgall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hanna Elizabeth Witzgall (Chantilly, Virginia); Timothy F. Settle (Leesburg, Virginia) |
| ASSIGNEE(S) | Science Applications International Corporation (McLean, Virginia) |
| INVENTOR(S) | Hanna Elizabeth Witzgall (Chantilly, Virginia); Timothy F. Settle (Leesburg, Virginia) |
| ABSTRACT | Complex image data is transformed to a holographic representation of the image. A subset of the holographic representation is modeled. Model parameters constitute a compressed image representation. A two-dimensional Fourier transform can be applied to obtain the holographic image. Modeling includes applying an analysis portion of an adaptive analysis/synthesis linear prediction methodology to a subset of the holographic representation to obtain an autoregressive model. Prior to modeling, one-dimensional Fourier transform can be performed on the holographic representation and the linear prediction is one-dimensional. Model parameters are preferably quantized. Embodiments include determining error between the model and the model's input data. There the compressed image representation the error, which also can be quantized. The subset of the holographic representation can be less than all the representation. The subset can be a plurality of complete rows; preferably substantially symmetric about 0 Hz. |
| FILED | Thursday, December 20, 2007 |
| APPL NO | 12/004027 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/232 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08420072 | Shoemaker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Craig A. Shoemaker (Notasulga, Alabama); Benjamin R. LaFentz (Auburn, Alabama) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Craig A. Shoemaker (Notasulga, Alabama); Benjamin R. LaFentz (Auburn, Alabama) |
| ABSTRACT | Vibrio vulnificus can cause infections in aquaculture-raised fish and is considered an opportunistic human pathogen. We isolated V. vulnificus from diseased hybrid tilapia (Oreochromis niloticus X O. aureus) cultured in a North American water reuse aquaculture facility. We have characterized the isolate using biochemical and molecular methods, developed a disease infection model, and determined that formalin-inactivated whole-cell vaccine provides protection against V. vulnificus. The V. vulnificus isolate was determined to be biotype 1, 16S rRNA type B, vcg type C, and vvhA type 2. Fish vaccinated with the formalin-inactivated whole-cell vaccine responded to vaccination as measured by agglutinating antibody titer. In two separate trials, vaccinated tilapia exhibited relative percent survival of 73 and 60% following challenge with the homologous isolate. In additional trials, vaccinated tilapia exhibited survival values of up to 87.5% following challenge with a heterologous isolate. Use of a mineral oil adjuvant enhanced protection. |
| FILED | Thursday, March 24, 2011 |
| APPL NO | 13/071193 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 08419213 | Rubtsov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vladimir Rubtsov (Los Angeles, California); Michael Levin (Los Angeles, California); Gennady Sigal (Oakville, Canada) |
| ASSIGNEE(S) | Vladimir Rubtsov (Los Angeles, California) |
| INVENTOR(S) | Vladimir Rubtsov (Los Angeles, California); Michael Levin (Los Angeles, California); Gennady Sigal (Oakville, Canada) |
| ABSTRACT | Apparatus and method for using a light source having spatially separated light emitting areas emitting light at different wavelengths to incapacitate a subject by a pattern of temporal flashing and/or color flashing of the light source. Also, power circuitry and optics particularly suited for flashing light incapacitation are included. |
| FILED | Saturday, October 23, 2010 |
| APPL NO | 12/910796 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Illumination 362/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08419945 | Browning et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David M. Browning (Portland, Oregon); James R. Curtis (Portland, Oregon); Goran Nadezda Jovanovic (Corvallis, Oregon); Brian Kevin Paul (Corvallis, Oregon); Sundar Atre (Corvallis, Oregon) |
| ASSIGNEE(S) | State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvalis, Oregon); Home Dialysis Plus (Portland, Oregon) |
| INVENTOR(S) | David M. Browning (Portland, Oregon); James R. Curtis (Portland, Oregon); Goran Nadezda Jovanovic (Corvallis, Oregon); Brian Kevin Paul (Corvallis, Oregon); Sundar Atre (Corvallis, Oregon) |
| ABSTRACT | The present invention provides methods and apparatus for cleansing blood through hemodialysis by the process of diffusion across a membrane into dialysate. This dialyzer also removes solutes from the blood by a process of convection, where fluid and dissolved solutes pass through the membrane out of the blood. In one embodiment in accordance with the present invention, the MECS dialyzer uses a counter-flow between the dialysate and blood through a plurality of microchannels. The dialyzer comprises a plurality of flat semi-permeable membranes interleaved between microchannel sheets to define a plurality of flow channels. The stack of membranes and microchannel sheets are aligned and consolidated to form the MECS dialyzer. The MECS dialyzer acts as a flow manifold with ports and headers to collect the blood and dialysate and direct them to and from the microchannels. |
| FILED | Monday, March 05, 2012 |
| APPL NO | 13/412597 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/646 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 08423375 | Amonette et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas M. Amonette (Greenfield, Indiana); John J. Sadler (Deinkirk, Maryland); John F. Gullo (Alexandria, Virginia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Thomas M. Amonette (Greenfield, Indiana); John J. Sadler (Deinkirk, Maryland); John F. Gullo (Alexandria, Virginia) |
| ABSTRACT | Methods and apparatus for manifesting mailpieces, processing mailpieces from a mail system, and certifying a mail system are provided. A mailpiece is received at a manifest mailing system and mailing information from the mailpiece is obtained. A manifest of the mailpiece is created and the mailpiece is then delivered using the manifest. Based on a certification of the mail system, an accuracy of a portion of the manifest may be selectively determined. Based on the accuracy of the portion of the manifest, the mailpieces are then conditionally delivered using the manifest. To determine a certification, test information may be provided to a mail system. A manifest generated by the mail system is then received. The accuracy of the manifest based on the test information is determine and a certification level is then assigned to the mail system. |
| FILED | Wednesday, February 22, 2006 |
| APPL NO | 11/358139 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 16, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130416.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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