FedInvent™ Patents
Patent Details for Tuesday, May 21, 2013
This page was updated on Monday, March 27, 2023 at 03:47 AM GMT
Department of Health and Human Services (HHS)
| US 08444268 | Hammer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Daniel X. Hammer (Bedford, New Hampshire); R. Daniel Ferguson (Melrose, Massachusetts); Nicusor V. Iftimia (Chelmsford, Massachusetts); Teoman E. Ustun (Malden, Massachusetts) |
| ASSIGNEE(S) | Physical Sciences, Inc. (Andover, Massachusetts) |
| INVENTOR(S) | Daniel X. Hammer (Bedford, New Hampshire); R. Daniel Ferguson (Melrose, Massachusetts); Nicusor V. Iftimia (Chelmsford, Massachusetts); Teoman E. Ustun (Malden, Massachusetts) |
| ABSTRACT | A system provides an optical image of an object. A first module tracks a reference feature of the object. A second module includes a source for an imaging beam, a scanning device to move the imaging beam along a portion of the object and a detection device receives a signal associated with an image of the portion of the object. The first module controls the position of the imaging beam relative to the reference feature to correct for the motion of the object. A third module detects a distortion of the object and compensates for the distortion. |
| FILED | Wednesday, January 19, 2011 |
| APPL NO | 13/009457 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444683 | Mahadevan-Jansen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Anita Mahadevan-Jansen (Nashville, Tennessee); Jonathon D. Wells (Seattle, Washington); E. Duco Jansen (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Anita Mahadevan-Jansen (Nashville, Tennessee); Jonathon D. Wells (Seattle, Washington); E. Duco Jansen (Nashville, Tennessee) |
| ABSTRACT | The present invention, in one aspect, relates to a method for stimulating neural tissue of a living subject. In one embodiment, the method has the steps of generating at least one beam of radiation; introducing at least one of one or more chromophores and one or more optical agents to a target neural tissue; and delivering the at least one beam of radiation to the target neural tissue, wherein the at least one beam of radiation is delivered with a radiant exposure that causes a thermal gradient in the target neural tissue, thereby stimulating the target neural tissue. |
| FILED | Tuesday, November 27, 2007 |
| APPL NO | 11/945649 |
| ART UNIT | 3769 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444963 | Cheong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ian Cheong (Baltimore, Maryland); Shibin Zhou (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ASSIGNEE(S) | John Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Ian Cheong (Baltimore, Maryland); Shibin Zhou (Baltimore, Maryland); Kenneth W. Kinzler (Bel Air, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ABSTRACT | Clostridium novyi is an obligate anaerobe that can infect hypoxic regions within experimental tumors. We found that mice bearing large, established tumors were often cured when treated with C. novyi plus a single dose of liposomal doxorubicin. The secreted factor responsible for this phenomenon was identified and, surprisingly, proved to be a member of the lipase family. The gene encoding this protein, called liposomase, has the potential to be incorporated into diverse therapeutic methods to deliver specifically a variety of chemotherapeutic agents to tumors. |
| FILED | Tuesday, June 19, 2007 |
| APPL NO | 12/304178 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444965 | Ostrand-Rosenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Suzanne Ostrand-Rosenberg (Columbia, Maryland); Jacobus J. Bosch (Baltimore, Maryland); Bruce R. Ksander (Belmont, Massachusetts) |
| ASSIGNEE(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
| INVENTOR(S) | Suzanne Ostrand-Rosenberg (Columbia, Maryland); Jacobus J. Bosch (Baltimore, Maryland); Bruce R. Ksander (Belmont, Massachusetts) |
| ABSTRACT | The present invention relates to tumor cell-based vaccines and methods of using same, wherein the vaccines are based on naturally immune privileged tumor cells that have been genetically modified to express MHC-II restricted peptides derived from endogenously encoded tumor antigens, activate CD4+ T-lymphocytes, provide an array of antigens to which the host is not tolerized and/or induce immunity against the originating tumor cells as well as against metastatic tumor cells. |
| FILED | Thursday, September 23, 2010 |
| APPL NO | 12/889043 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444972 | Rock et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kenneth L. Rock (Chestnut Hill, Massachusetts); Dancella Fernandes (Framingham, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Kenneth L. Rock (Chestnut Hill, Massachusetts); Dancella Fernandes (Framingham, Massachusetts) |
| ABSTRACT | Antibodies that bind to a 40 kDa protein which is expressed on tumors, but is not expressed on normal adult hemopoietic cells are disclosed. Also disclosed are methods for production and the use of such antibodies. |
| FILED | Thursday, August 05, 2010 |
| APPL NO | 12/851127 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444973 | Tedder et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas F. Tedder (Durham, North Carolina); Yasuhito Hamaguchi (Kanazawa, Japan); Hanne Gron (Durham, North Carolina); Norihito Yazawa (Tokyo, Japan) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Thomas F. Tedder (Durham, North Carolina); Yasuhito Hamaguchi (Kanazawa, Japan); Hanne Gron (Durham, North Carolina); Norihito Yazawa (Tokyo, Japan) |
| ABSTRACT | The invention relates to immunotherapeutic compositions and methods for the treatment of B cell diseases and disorders in human subjects, such as, but not limited to, B cell malignancies and autoimmune diseases and disorders, using therapeutic antibodies that bind to the human CD19 antigen and that preferably mediate human ADCC. The present invention relates to pharmaceutical compositions comprising human or humanized anti-CD19 antibodies of the IgG1 or IgG3 human isotype. The present invention relates to pharmaceutical compositions comprising human or humanized anti-CD19 antibodies of the IgG2 or IgG4 human isotype that preferably mediate human ADCC. The present invention also relates to pharmaceutical compositions comprising chimerized anti-CD19 antibodies of the IgG1, IgG2, IgG3, or IgG4 isotype that mediate human ADCC. In preferred embodiments, the present invention relates to pharmaceutical compositions comprising monoclonal human, humanized, or chimeric anti-CD19 antibodies. |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/885341 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444985 | Ibrahim et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ashraf S. Ibrahim (Irvine, California); Brad J. Spellberg (Rancho Palos Verdes, California); Yue Fu (Torrance, California); John E. Edwards (Palos Verdes Estates, California) |
| ASSIGNEE(S) | Los Angeles Biomedical Research Institute at Harbor-ULCA Medical Center (Torrance, California) |
| INVENTOR(S) | Ashraf S. Ibrahim (Irvine, California); Brad J. Spellberg (Rancho Palos Verdes, California); Yue Fu (Torrance, California); John E. Edwards (Palos Verdes Estates, California) |
| ABSTRACT | The present invention provides therapeutic compositions and methods for treating and preventing fungal disease or conditions including mucormycosis. The therapeutic methods and compositions of the invention include vaccine compositions having an FTR polypeptide or an antigenic fragment of the polypeptide; a vector including a nucleotide sequence that is substantially complimentary to at least 18 contiguous nucleotides of FTR sequence; an antisense; a small interfering RNA or an antibody inhibitor of FTR. The vaccine compositions of the invention can further include an adjuvant. |
| FILED | Friday, March 19, 2010 |
| APPL NO | 12/661609 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/146.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444991 | Randolph et al. |
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| FUNDED BY |
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| APPLICANT(S) | Theodore W. Randolph (Niwot, Colorado); Amber Clausi (Easton, Pennsylvania); John F. Carpenter (Littleton, Colorado); Daniel K. Schwartz (Boulder, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Theodore W. Randolph (Niwot, Colorado); Amber Clausi (Easton, Pennsylvania); John F. Carpenter (Littleton, Colorado); Daniel K. Schwartz (Boulder, Colorado) |
| ABSTRACT | The disclosure provides a method of preparing an immunologically-active adjuvant-bound freeze dried vaccine composition. A specific embodiment provides a stable vaccine composition comprising an aluminum-salt adjuvant, a recombinant Clostridium botulinum neurotoxin protein and a glass-forming agent. These vaccine compositions are useful in the treatment of humans and other animals at risk of infection from Clostridium botulinum neurotoxin. |
| FILED | Tuesday, March 18, 2008 |
| APPL NO | 12/532225 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444996 | Schneerson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rachel Schneerson (Bethesda, Maryland); Joanna Kubler-Kielb (Bethesda, Maryland); John B. Robbins (New York, New York); Fathy Majadly (Frederick, Maryland); Christopher P. Mocca (Columbia, Maryland); Jerry Keith (Olney, North Carolina); Zuzana Biesova (Rockville, Maryland); Louis Miller (Cabin John, Maryland); Ruth Nussenzweig (New York, New York); Darrell T. Liu (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); New York University (New York, New York) |
| INVENTOR(S) | Rachel Schneerson (Bethesda, Maryland); Joanna Kubler-Kielb (Bethesda, Maryland); John B. Robbins (New York, New York); Fathy Majadly (Frederick, Maryland); Christopher P. Mocca (Columbia, Maryland); Jerry Keith (Olney, North Carolina); Zuzana Biesova (Rockville, Maryland); Louis Miller (Cabin John, Maryland); Ruth Nussenzweig (New York, New York); Darrell T. Liu (Bethesda, Maryland) |
| ABSTRACT | Disclosed are immunogenic conjugates which elicit an immune response to Plasmodium proteins. In particular examples, the Plasmodium proteins include sexual stage surface proteins, circumsporozoite protein (CSP), or immunogenic portions of CSP. Also provided herein are immunogenic compositions including one or more of the disclosed immunogenic conjugates and a pharmaceutically acceptable carrier. Further provided is a method of eliciting an immune response to Plasmodium in a subject, comprising administering to the subject an immunogenic composition disclosed herein. |
| FILED | Thursday, October 01, 2009 |
| APPL NO | 13/121574 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/193.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445006 | Garcia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Andrés J. Garcia (Atlanta, Georgia); Catherine D. Reyes (Miami, Florida); Timothy Petrie (Atlanta, Georgia); Zvi Schwartz (Atlanta, Georgia); Barbara Boyan (Atlanta, Georgia); Jenny E. Raynor (E. Sandwich, Georgia); David M. Collard (Atlanta, Georgia); Abigail M. Wojtowicz (Atlanta, Georgia); Robert E. Guldberg (Marietta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Andrés J. Garcia (Atlanta, Georgia); Catherine D. Reyes (Miami, Florida); Timothy Petrie (Atlanta, Georgia); Zvi Schwartz (Atlanta, Georgia); Barbara Boyan (Atlanta, Georgia); Jenny E. Raynor (E. Sandwich, Georgia); David M. Collard (Atlanta, Georgia); Abigail M. Wojtowicz (Atlanta, Georgia); Robert E. Guldberg (Marietta, Georgia) |
| ABSTRACT | Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are provided. The substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are shown to have greater tissue formation on the surface relative to controls, in particular greater bone formation. |
| FILED | Monday, February 13, 2012 |
| APPL NO | 13/372234 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445190 | Lambris et al. |
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| APPLICANT(S) | John D. Lambris (Philadelphia, Pennsylvania); Konstantinos Ritis (Alexandroupolis, Greece) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | John D. Lambris (Philadelphia, Pennsylvania); Konstantinos Ritis (Alexandroupolis, Greece) |
| ABSTRACT | Methods for reducing or eliminating biomaterial-induced procoagulant activity in blood subjected to extracorporeal treatment that exposes the blood to the biomaterial are disclosed. The methods involve treatment of the blood, or the extracorporeal biomaterial, or both, with a complement inhibitor to inhibit C5a/C5aR-mediated tissue factor formation in the blood. |
| FILED | Tuesday, September 29, 2009 |
| APPL NO | 13/121396 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445194 | Drmanac et al. |
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| FUNDED BY |
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| APPLICANT(S) | Radoje Drmanac (Los Altos Hills, California); Matthew J. Callow (Redwood City, California); Snezana Drmanac (Los Altos Hills, California); Brian K. Hauser (Campbell, California); George Yeung (Mountain View, California) |
| ASSIGNEE(S) | Callida Genomics, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Radoje Drmanac (Los Altos Hills, California); Matthew J. Callow (Redwood City, California); Snezana Drmanac (Los Altos Hills, California); Brian K. Hauser (Campbell, California); George Yeung (Mountain View, California) |
| ABSTRACT | Random arrays of single molecules are provided for carrying out large scale analyses, particularly of biomolecules, such as genomic DNA, cDNAs, proteins, and the like. In one aspect, arrays of the invention comprise concatemers of DNA fragments that are randomly disposed on a regular array of discrete spaced apart regions, such that substantially all such regions contain no more than a single concatemer. Preferably, such regions have areas substantially less than 1 μm2 and have nearest neighbor distances that permit optical resolution of on the order of 109 single molecules per cm2. Many analytical chemistries can be applied to random arrays of the invention, including sequencing by hybridization chemistries, sequencing by synthesis chemistries, SNP detection chemistries, and the like, to greatly expand the scale and potential applications of such techniques. |
| FILED | Tuesday, June 13, 2006 |
| APPL NO | 11/451691 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445196 | Drmanac et al. |
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| FUNDED BY |
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| APPLICANT(S) | Radoje T. Drmanac (Los Altos Hills, California); Matthew J. Callow (Redwood City, California); Snezana Drmanac (Los Altos Hills, California); Brian K. Hauser (Campbell, California); George Yeung (Mountain View, California) |
| ASSIGNEE(S) | Callida Genomics, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Radoje T. Drmanac (Los Altos Hills, California); Matthew J. Callow (Redwood City, California); Snezana Drmanac (Los Altos Hills, California); Brian K. Hauser (Campbell, California); George Yeung (Mountain View, California) |
| ABSTRACT | Random arrays of single molecules are provided for carrying out large scale analyses, particularly of biomolecules, such as genomic DNA, cDNAs, proteins, and the like. In one aspect, arrays of the invention comprise concatemers of DNA fragments that are randomly disposed on a regular array of discrete spaced apart regions, such that substantially all such regions contain no more than a single concatemer. Preferably, such regions have areas substantially less than 1 μm2 and have nearest neighbor distances that permit optical resolution of on the order of 109 single molecules per cm2. Many analytical chemistries can be applied to random arrays of the invention, including sequencing by hybridization chemistries, sequencing by synthesis chemistries, SNP detection chemistries, and the like, to greatly expand the scale and potential applications of such techniques. |
| FILED | Wednesday, October 31, 2007 |
| APPL NO | 11/981767 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445197 | Drmanac et al. |
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| FUNDED BY |
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| APPLICANT(S) | Radoje Drmanac (Los Altos Hills, California); Matthew J. Callow (Redwood City, California); Snezana Drmanac (Los Altos Hills, California); Brian K. Hauser (Campbell, California); George Yeung (Mountain View, California) |
| ASSIGNEE(S) | Callida Genomics, Inc. (Sunnyvale, California) |
| INVENTOR(S) | Radoje Drmanac (Los Altos Hills, California); Matthew J. Callow (Redwood City, California); Snezana Drmanac (Los Altos Hills, California); Brian K. Hauser (Campbell, California); George Yeung (Mountain View, California) |
| ABSTRACT | Random arrays of single molecules are provided for carrying out large scale analyses, particularly of biomolecules, such as genomic DNA, cDNAs, proteins, and the like. In one aspect, arrays of the invention comprise concatemers of DNA fragments that are randomly disposed on a regular array of discrete spaced apart regions, such that substantially all such regions contain no more than a single concatemer. Preferably, such regions have areas substantially less than 1 μm2 and have nearest neighbor distances that permit optical resolution of on the order of 109 single molecules per cm2. Many analytical chemistries can be applied to random arrays of the invention, including sequencing by hybridization chemistries, sequencing by synthesis chemistries, SNP detection chemistries, and the like, to greatly expand the scale and potential applications of such techniques. |
| FILED | Wednesday, October 31, 2007 |
| APPL NO | 11/982467 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445200 | Westbrook et al. |
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| FUNDED BY |
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| APPLICANT(S) | Aya M. Westbrook (Cypress, California); Robert H. Schiestl (Encino, California); Bo Wei (Rancho Palos Verdes, California); Jonathan Braun (Tarzana, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aya M. Westbrook (Cypress, California); Robert H. Schiestl (Encino, California); Bo Wei (Rancho Palos Verdes, California); Jonathan Braun (Tarzana, California) |
| ABSTRACT | The invention provides a method for detection of inflammatory disease in a subject that comprises assaying a test sample of peripheral blood from the subject for a marker of DNA damage. An elevated amount of marker present in the test sample compared to control sample is indicative of inflammatory disease activity, including sub-clinical inflammation. The method can be adapted for quantitatively monitoring the efficacy of treatment of inflammatory disease in a subject. Markers of DNA damage include single- and/or double-stranded breaks in leukocytes, oxidative DNA damage in leukocytes, or a marker of nitric oxide oxidative activity (protein nitrosylation in leukocytes). The inflammatory disease can be inflammatory bowel disease (ulcerative colitis or Crohn's disease). The invention may also be used for detection of other types of inflammatory disease, such as non-immune intestinal inflammatory disease (diverticulitis, pseudomembranous colitis), autoimmune diseases (rheumatoid arthritis, lupus, multiple sclerosis, psoriasis, uveitis, vasculitis), or non-immune lung diseases (asthma, chronic obstructive lung disease, and interstitial pneumonitis). This unexpected discovery of markers of genotoxicity present in circulating leukocytes enables detection of inflammation occurring at a localized site with a relatively simple and minimally invasive assay using peripheral blood. |
| FILED | Thursday, April 15, 2010 |
| APPL NO | 12/761330 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445216 | Kuan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Chien-Tsun Kuan (Cary, North Carolina); Darell D Bigner (Mebane, North Carolina); Ira H Pastan (Potomac, Maryland) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); The United States of America, as represented by the Secretary of Health and Human Services, National Institutes of Health (Washington, District of Columbia) |
| INVENTOR(S) | Chien-Tsun Kuan (Cary, North Carolina); Darell D Bigner (Mebane, North Carolina); Ira H Pastan (Potomac, Maryland) |
| ABSTRACT | The invention provides high affinity antibodies suitable for forming Immunotoxins that inhibit the growth of cells expressing human glycoprotein NMB, including glioblastoma multiform cells, anaplastic astrocytoma cells, anaplastic oligodendroglioma cells, oligodendroglioma cells, and melanoma cells. |
| FILED | Tuesday, October 18, 2011 |
| APPL NO | 13/276012 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445217 | Bornhop |
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| FUNDED BY |
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| APPLICANT(S) | Darryl J. Bornhop (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Darryl J. Bornhop (Nashville, Tennessee) |
| ABSTRACT | Disclosed are methods, systems, and apparatuses for the free solution measurement of molecular interactions by backscattering interferometry (BSI). Molecular interaction can be detected between analytes in free-solution wherein at least one of the analytes is label-free and detection is performed by back-scattering interferometry. Further, molecular interaction can be detected between analytes in free-solution, wherein at least one of the analytes is label-free, wherein one of the analytes is present in a concentration of less than about 5.0×10−7M. Also disclosed are label-free, free-solution, and/or real-time measurements of characteristic properties and/or chemical events using the disclosed techniques. The disclosed methods can have very low detection limits and/or very low sample volume requirements. Also disclosed are various biosensor applications of the disclosed techniques. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Saturday, September 20, 2008 |
| APPL NO | 12/674610 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445225 | Kuhn et al. |
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| FUNDED BY |
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| APPLICANT(S) | Peter Kuhn (Solana Beach, California); John Ho Griffin (Del Mar, California); Kelly Bethel (San Diego, California); Dena Marrinucci (Del Mar, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Peter Kuhn (Solana Beach, California); John Ho Griffin (Del Mar, California); Kelly Bethel (San Diego, California); Dena Marrinucci (Del Mar, California) |
| ABSTRACT | The present invention provides methods for revealing, detecting, and analyzing circulating tumor cells in the blood of a subject. Revealing detectable circulating tumor cells allows for early stage detection and diagnosis in addition to long term prognosis in subjects with cancer. Additionally, enrichment allows for robust detection and clinically meaningful analysis of low volume samples for use in clinical settings as well as innovative methods for the treatment of cancers. |
| FILED | Thursday, September 03, 2009 |
| APPL NO | 12/553733 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445228 | Hamad-Schifferli et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kimberly S. Hamad-Schifferli (Somerville, Massachusetts); Sunho Park (Silver Spring, Maryland) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kimberly S. Hamad-Schifferli (Somerville, Massachusetts); Sunho Park (Silver Spring, Maryland) |
| ABSTRACT | Provided herein are kits and methods suitable for enhancing in vitro translation of a nuclei acid sequence of interest. |
| FILED | Monday, December 14, 2009 |
| APPL NO | 12/637743 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445233 | Spiegelman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jiandie Lin (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jiandie Lin (Ann Arbor, Michigan) |
| ABSTRACT | The invention provides isolated nucleic acid molecules, designated PGC-1β nucleic acid molecules, which encode novel PGC-1 related coactivator molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PGC-1β nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PGC-1β gene has been introduced or disrupted. The invention still further provides isolated PGC-1β proteins, fusion proteins, antigenic peptides and anti-PGC-1β antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |
| FILED | Wednesday, December 21, 2011 |
| APPL NO | 13/333210 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445254 | Curtiss, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | Roy Curtiss, III (Paradise Valley, Arizona); Shifeng Wang (Tempe, Arizona); Soo-Young Wanda (Chandler, Arizona); Wei Kong (Phoenix, Arizona) |
| ASSIGNEE(S) | The Arizona Board of Regents for and on Behalf of Arizona State University (Tempe, Arizona); The Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Roy Curtiss, III (Paradise Valley, Arizona); Shifeng Wang (Tempe, Arizona); Soo-Young Wanda (Chandler, Arizona); Wei Kong (Phoenix, Arizona) |
| ABSTRACT | The invention relates to compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest. |
| FILED | Tuesday, November 10, 2009 |
| APPL NO | 12/615872 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445267 | Zhong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Li Zhong (Gainesville, Florida); Sergei Zolotukhin (Gainesville, Florida); Lakshmanan Govindasamy (Gainesville, Florida); Mavis Agbandje-McKenna (Gainesville, Florida); Arun Srivastava (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Li Zhong (Gainesville, Florida); Sergei Zolotukhin (Gainesville, Florida); Lakshmanan Govindasamy (Gainesville, Florida); Mavis Agbandje-McKenna (Gainesville, Florida); Arun Srivastava (Gainesville, Florida) |
| ABSTRACT | Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors. |
| FILED | Tuesday, April 08, 2008 |
| APPL NO | 12/595196 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445272 | Savage et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul B. Savage (Mapleton, Utah); Albert Bendelac (Chicago, Illinois); Luc Teyton (Delmar, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California); The University of Chicago (Chicago, Illinois); Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Paul B. Savage (Mapleton, Utah); Albert Bendelac (Chicago, Illinois); Luc Teyton (Delmar, California) |
| ABSTRACT | This invention relates to galactosylceramide compounds. |
| FILED | Tuesday, August 02, 2011 |
| APPL NO | 13/196631 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08445281 — In vitro exposure of immature oocytes to BDNF enhances generation of embryonic stem cells
| US 08445281 | Kawamura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kazuhiro Kawamura (Akita, Japan); Aaron J. W. Hsueh (Stanford, California); Sabine M. Mulders (Oss, Netherlands) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Kazuhiro Kawamura (Akita, Japan); Aaron J. W. Hsueh (Stanford, California); Sabine M. Mulders (Oss, Netherlands) |
| ABSTRACT | Compositions and methods are provided for enhancing the survival and promoting the maturation of mammalian oocytes, zygotes and preimplantation embryos. BDNF or BDNF agonists may be administered to an individual, or to cells in vitro, to enhance cellular maturation, embryo growth and fertilization. Accordingly, compositions comprising BDNF are herein presented for use in promoting in vivo oocyte maturation as well as for use as a component in culture media for promoting preimplantation maturation of zygotes and embryos, for instance, for use with in vitro fertilization procedures and for the production of stem cells. Additionally, compounds that interfere with the binding of BDNF to its receptor may be administered to an individual to prevent oocyte maturation, thereby acting as a contraceptive. The BNDF receptor, TrkB, and BDNF also find use in the screening and design of agonists and antagonists for use in the methods of the invention. |
| FILED | Thursday, June 17, 2010 |
| APPL NO | 12/818055 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/397 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445412 | Hirschbein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bernard Hirschbein (Hayward, California); Filiz Gorpe-Yasar (Hayward, California) |
| ASSIGNEE(S) | Illumina, Inc. (San Diego, California) |
| INVENTOR(S) | Bernard Hirschbein (Hayward, California); Filiz Gorpe-Yasar (Hayward, California) |
| ABSTRACT | The present technology relates to methods and systems for detection of pyrophosphate. As such, disclosed herein are methods and systems that permit improved pyrophosphate detection. Also disclosed herein are methods and systems which utilize improved pyrophosphate detection for nucleotide sequencing. |
| FILED | Wednesday, February 24, 2010 |
| APPL NO | 13/203463 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445435 | Shi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Guo-Ping Shi (Newton, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Guo-Ping Shi (Newton, Massachusetts) |
| ABSTRACT | The present invention is directed to methods of treating or preventing the development of obesity by administering compounds that stabilize mast cells. In addition, it includes pharmaceutical compositions which have both a mast cell stabilizer and instructions regarding the use of the stabilizer in treating or preventing obesity. |
| FILED | Wednesday, September 24, 2008 |
| APPL NO | 12/232789 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/8.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445437 | Shi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Guo-Ping Shi (Newton, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Guo-Ping Shi (Newton, Massachusetts) |
| ABSTRACT | The present invention is directed to methods of treating or preventing the development of cardiovascular disease by administering compounds that stabilize mast cells. In addition, it includes pharmaceutical compositions which have both a mast cell stabilizer and instructions regarding the use of the stabilizer in treating or preventing cardiovascular disease. The methods and compositions will be of particular value for preventing aneurysms of the abdominal aorta in individuals with atherosclerosis, diabetes, hypertension or a family history of aneurysms. |
| FILED | Tuesday, July 24, 2007 |
| APPL NO | 11/878419 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/16.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445441 | Distelhorst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clark W. Distelhorst (Shaker Heights, Ohio); Yiping Rong (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Clark W. Distelhorst (Shaker Heights, Ohio); Yiping Rong (Cleveland, Ohio) |
| ABSTRACT | A purified polypeptide for inhibiting binding of BCL-2 to IP3 receptors includes an amino acid sequence consisting of about 10 to 80 amino acids. The amino acid sequence has a sequence identity at least 90% homologous to a portion of SEQ ID NO:1. The polypeptide inhibits binding of Bcl-2 to IP3 receptors of cells that express IP3R and Bcl-2 and induces apoptosis in a cell. |
| FILED | Friday, August 26, 2011 |
| APPL NO | 13/218818 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/18.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445446 | Deiters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Deiters (La Jolla, California); Ashton T. Cropp (Bethesda, Maryland); Jason W. Chin (Cambridge, United Kingdom); Christopher J. Anderson (San Francisco, California); Peter G. Schultz (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Alexander Deiters (La Jolla, California); Ashton T. Cropp (Bethesda, Maryland); Jason W. Chin (Cambridge, United Kingdom); Christopher J. Anderson (San Francisco, California); Peter G. Schultz (La Jolla, California) |
| ABSTRACT | This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. |
| FILED | Thursday, June 23, 2011 |
| APPL NO | 13/135129 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/20.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445447 | Chen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lieping Chen (New Haven, Connecticut) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Lieping Chen (New Haven, Connecticut) |
| ABSTRACT | Compositions and methods for costimulating T cells (i.e., increasing antigen-specific proliferation of T cells, enhancing cytokine production by T cells, stimulating differentiation ad effector functions of T cells and/or promoting T cell survival) are provided. Suitable compositions include variant B7-DC polypeptides, fragments and fusion proteins thereof. Variant B7-DC polypeptides have reduced binding affinity for the inhibitory PD-1 ligand and substantially retain the ability to costimulate T cells. Methods for using variant B7-DC polypeptides to stimulate immune responses in subjects in need thereof are provided. |
| FILED | Wednesday, March 07, 2012 |
| APPL NO | 13/413990 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445449 | Hefeneider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Department of Veterans Affairs (Washington, District of Columbia); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | The United States of America, as represented by the Department of Veterans Affairs (Washington, District of Columbia); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Steven H. Hefeneider (Portland, Oregon); Sharon L. McCoy (Portland, Oregon) |
| ABSTRACT | Method and peptide for regulating cellular activity includes a panel of synthesized peptides that have biological effects on inhibiting or enhancing cellular activity. Selected peptides can be used as therapy to reduce and/or inhibit, or initiate and/or enhance, an inflammatory response in a subject. |
| FILED | Tuesday, October 23, 2012 |
| APPL NO | 13/658687 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445455 | Lee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amy Lee (San Marino, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Amy Lee (San Marino, California) |
| ABSTRACT | This invention relates to compositions and methods for selective expression of a heterologous nucleic acid sequence in a targeted tissue, and more particularly to the glucose regulated protein 78 (grp78) stress-responsive promoter and its use in gene therapy and the production of transgenic animals. |
| FILED | Tuesday, April 12, 2011 |
| APPL NO | 13/084772 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445467 | Shoelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven Shoelson (Natick, Massachusetts); Allison B. Goldfine (Wayland, Massachusetts) |
| ASSIGNEE(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Steven Shoelson (Natick, Massachusetts); Allison B. Goldfine (Wayland, Massachusetts) |
| ABSTRACT | This invention relates to methods for reducing chronic subacute inflammatory states associated with obesity and improve glycemia, thereby preventing or delaying the development of type 2 diabetes (T2D) in obese subjects, or subjects with the metabolic syndrome, using non-acetylated forms of salicylate, e.g., salsalate or trilisate. |
| FILED | Friday, April 27, 2007 |
| APPL NO | 12/298627 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/159 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445473 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shaomeng Wang (Saline, Michigan); Haiying Sun (Ann Arbor, Michigan); Zaneta Nikolovska-Coleska (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Shaomeng Wang (Saline, Michigan); Haiying Sun (Ann Arbor, Michigan); Zaneta Nikolovska-Coleska (Ann Arbor, Michigan) |
| ABSTRACT | The invention relates to heteroaryl-substituted bicyclic mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis. |
| FILED | Monday, April 13, 2009 |
| APPL NO | 12/937114 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445483 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ching-Shih Chen (Upper Arlington, Ohio); Hao-Chieh Chiu (Columbus, Ohio); Dasheng Wang (Dublin, Ohio); John S. Gunn (Powell, Ohio); Larry S. Schlesinger (Powell, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ching-Shih Chen (Upper Arlington, Ohio); Hao-Chieh Chiu (Columbus, Ohio); Dasheng Wang (Dublin, Ohio); John S. Gunn (Powell, Ohio); Larry S. Schlesinger (Powell, Ohio) |
| ABSTRACT | A new class of phosphoinositide-dependent kinase-1 (PDK-1) inhibitors of Formula I: wherein X wherein X is —CF3, Ar is selected from and R is selected from where R′ is L-Lys, D-Lys, β-Ala, L-Lue, L-Ile, Phe, SO2CH2CH2NH2, SO2NH2, Asn, Glu or Gyl, and R″ is methyl, ethyl, allyl, CH2CH2OH, CH2CN, CH2CH2CN, CH2CONH2, |
| FILED | Friday, October 07, 2011 |
| APPL NO | 13/267943 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/225.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445491 | Lum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Lum (Dallas, Texas); Michael G. Roth (Dallas, Texas); Baozhi Chen (Addison, Texas); Chuo Chen (Dallas, Texas); Michael E. Dodge (Irving, Texas); Wei Tang (Beijing, China PRC) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Lawrence Lum (Dallas, Texas); Michael G. Roth (Dallas, Texas); Baozhi Chen (Addison, Texas); Chuo Chen (Dallas, Texas); Michael E. Dodge (Irving, Texas); Wei Tang (Beijing, China PRC) |
| ABSTRACT | The present invention generally relates to protein signalling. In particular, compounds that inhibit the Wnt protein signalling pathway are disclosed. Such compounds may be used in the treatment of Wnt protein signalling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis. |
| FILED | Wednesday, May 27, 2009 |
| APPL NO | 12/994661 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/248 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445518 | Charvat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trevor T. Charvat (San Jose, California); Cheng Hu (Menlo Park, California); Jeff Jin (Fremont, California); Yandong Li (San Jose, California); Anita Melikian (San Francisco, California); Andrew M. K. Pennell (San Francisco, California); Sreenivas Punna (Sunnyvale, California); Solomon Ungashe (Fremont, California); Yibin Zeng (San Mateo, California) |
| ASSIGNEE(S) | ChemoCentryx, Inc. (Mountain View, California) |
| INVENTOR(S) | Trevor T. Charvat (San Jose, California); Cheng Hu (Menlo Park, California); Jeff Jin (Fremont, California); Yandong Li (San Jose, California); Anita Melikian (San Francisco, California); Andrew M. K. Pennell (San Francisco, California); Sreenivas Punna (Sunnyvale, California); Solomon Ungashe (Fremont, California); Yibin Zeng (San Mateo, California) |
| ABSTRACT | Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, CCR9-mediated diseases, as controls in assays for the identification of CCR2 antagonists and as controls in assays for the identification of CCR9 antagonists. |
| FILED | Friday, February 19, 2010 |
| APPL NO | 12/708900 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/340 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445528 | Baker, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James R. Baker, Jr. (Ann Arbor, Michigan); Xue-min Cheng (Ann Arbor, Michigan); Thommey P. Thomas (Dexter, Michigan); Baohua Mark Huang (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | James R. Baker, Jr. (Ann Arbor, Michigan); Xue-min Cheng (Ann Arbor, Michigan); Thommey P. Thomas (Dexter, Michigan); Baohua Mark Huang (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer-linker conjugates, methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer-linker conjugates of the present invention may further comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy. |
| FILED | Thursday, July 12, 2012 |
| APPL NO | 13/547929 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/412 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445537 | Tomkinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan E. Tomkinson (Glenwood, Maryland); Xi Chen (Baltimore, Maryland); Barbara Dziegielewska (Baltimore, Maryland); Alexander D. Mackerell (Baltimore, Maryland); Shijun Zhong (Ellicott City, Maryland); Gerald M. Wilson (Middle River, Maryland) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Alan E. Tomkinson (Glenwood, Maryland); Xi Chen (Baltimore, Maryland); Barbara Dziegielewska (Baltimore, Maryland); Alexander D. Mackerell (Baltimore, Maryland); Shijun Zhong (Ellicott City, Maryland); Gerald M. Wilson (Middle River, Maryland) |
| ABSTRACT | Methods for treating cancer using compounds that inhibit human DNA ligases. Methods for using compounds that inhibit human DNA ligases to provide insights into the reaction mechanisms of human DNA ligases, for example to identify the human DNA ligase involved in different DNA repair pathways. Screening methods for compounds that inhibit human DNA ligases. |
| FILED | Friday, October 09, 2009 |
| APPL NO | 12/576410 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/615 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445588 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter X. Ma (Ann Arbor, Michigan); Jianxiang Zhang (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Peter X. Ma (Ann Arbor, Michigan); Jianxiang Zhang (Ann Arbor, Michigan) |
| ABSTRACT | A water soluble copolymer includes first and second hydrophilic block segments or graft chains. The first hydrophilic block segment or graft chain contains cyclodextrin groups in at least a majority of its repeating units, and the second hydrophilic block segment or graft chain contains repeating units other than cyclodextrin groups. The first and second block segments or graft chains are covalently linked. |
| FILED | Tuesday, August 18, 2009 |
| APPL NO | 12/543381 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 525/54.240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445632 | Barron et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Annelise E. Barron (Palo Alto, California); Ann M. Czyzewski (Grayslake, Illinois); Michelle T. Dohm (Palos Park, Illinois); Tyler M. Miller (Aurora, Colorado); Ronald N. Zuckermann (El Cerrito, California); James A. Patch (Cornwall-on-Hudson, New York); Nathaniel P. Chongsiriwatana (Albuquerque, New Mexico) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Annelise E. Barron (Palo Alto, California); Ann M. Czyzewski (Grayslake, Illinois); Michelle T. Dohm (Palos Park, Illinois); Tyler M. Miller (Aurora, Colorado); Ronald N. Zuckermann (El Cerrito, California); James A. Patch (Cornwall-on-Hudson, New York); Nathaniel P. Chongsiriwatana (Albuquerque, New Mexico) |
| ABSTRACT | Antimicrobial peptoid compounds and related compositions as can be used against bacteria effectively and selectively. |
| FILED | Monday, February 09, 2009 |
| APPL NO | 12/378034 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445648 | Rincon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mercedes Rincon (Burlington, Vermont); Tina M. Thornton (Essex Junction, Vermont) |
| ASSIGNEE(S) | University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Mercedes Rincon (Burlington, Vermont); Tina M. Thornton (Essex Junction, Vermont) |
| ABSTRACT | The invention relates to methods and compositions for regulation of GSK3β activity. The invention provides phosphorylated GSK3β polypeptides and antibodies that recognize such polypeptides. The invention further includes methods for treating disorders that are associated with elevated or reduced GSK3β activity. |
| FILED | Wednesday, April 29, 2009 |
| APPL NO | 12/989901 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445658 | Ko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert I. Ko (Salvador, Brazil); Mitermayer Galvão Reis (Salvador, Brazil); Julio Henrique Rosa Croda (Salvador, Brazil); Isadora Cristina Siqueira (Salvador, Brazil); David A. Haake (Los Angeles, California); James Matsunaga (Los Angeles, California); Lee W. Riley (Berkeley, California); Michele Barocchi (Los Angeles, California); Tracy Ann Young (Berkeley, California) |
| ASSIGNEE(S) | The United States of America represented by the Department of Veterans Affairs (Washington, District of Columbia); The Regents of the University of California (Oakland, California); Cornell Research Foundation, Inc. (Ithaca, New York); Fundação Oswaldo Cruz Fiocruz (Rio de Janeiro, Brazil) |
| INVENTOR(S) | Albert I. Ko (Salvador, Brazil); Mitermayer Galvão Reis (Salvador, Brazil); Julio Henrique Rosa Croda (Salvador, Brazil); Isadora Cristina Siqueira (Salvador, Brazil); David A. Haake (Los Angeles, California); James Matsunaga (Los Angeles, California); Lee W. Riley (Berkeley, California); Michele Barocchi (Los Angeles, California); Tracy Ann Young (Berkeley, California) |
| ABSTRACT | The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and their use in diagnostic, therapeutic and vaccine applications. According to the present invention, the isolated molecules encoding for BigL1, BigL2 and BigL3 proteins are used for the diagnosis and prevention of infection with Leptospira species that are capable of producing disease in humans and other mammals, including those of veterinary importance. |
| FILED | Friday, June 15, 2012 |
| APPL NO | 13/525157 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445660 | August et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas August (Baltimore, Maryland); Ernesto Marques, Jr. (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Thomas August (Baltimore, Maryland); Ernesto Marques, Jr. (Baltimore, Maryland) |
| ABSTRACT | The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient. |
| FILED | Monday, June 28, 2010 |
| APPL NO | 12/824835 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445684 | Chandrasekhar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jayaraman Chandrasekhar (Trumbull, Connecticut); Alan P. Kozikowski (Chicago, Illinois); Jianhua Liu (Chicago, Illinois); Werner Tueckmantel (Yorktown Heights, New York); Joel R. Walker (Schenectady, New York); Po-wai Yuen (Ann Arbor, Michigan) |
| ASSIGNEE(S) | PsycoGenics Inc. (Tarrytown, New York); The Board of Trustee of the University of IL (Urbana, Illinois) |
| INVENTOR(S) | Jayaraman Chandrasekhar (Trumbull, Connecticut); Alan P. Kozikowski (Chicago, Illinois); Jianhua Liu (Chicago, Illinois); Werner Tueckmantel (Yorktown Heights, New York); Joel R. Walker (Schenectady, New York); Po-wai Yuen (Ann Arbor, Michigan) |
| ABSTRACT | The invention relates to pyridinyl nicotinic acetylcholine receptor ligands, compositions comprising an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand and methods to treat or prevent a condition, such as depression and nicotine dependence, comprising administering to an animal in need thereof an effective amount of a pyridinyl nicotinic acetylcholine receptor ligand. |
| FILED | Tuesday, October 13, 2009 |
| APPL NO | 12/578020 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/256 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447089 | Liu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chunlei Liu (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chunlei Liu (Chapel Hill, North Carolina) |
| ABSTRACT | The present disclosure provides a method and system for quantifying and making images of tissue anisotropy property based on magnetic resonance imaging (MRI). The systems and methods provided herein utilize orientation distribution of magnetic susceptibility to characterize magnetic susceptibility anisotropy (MSA) inside biological tissues. This MSA may be intrinsic property of the tissue or may be induced by the presence of external agents. In certain embodiments, the MSA is displayed as an orientation distribution function of susceptibility and/or may be described by mathematical quantities such as tensors (e.g., symmetric or asymmetric second order or higher order tensors) and spherical harmonics. In other embodiments, the MSA is characterized using a second order tensor named apparent susceptibility tensor (AST). |
| FILED | Wednesday, April 27, 2011 |
| APPL NO | 13/095200 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447384 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sheng Xu (Rockville, Maryland); Jochen Kruecker (Washington, District of Columbia); Guy Shechter (Briarcliff Manor, New York); Ian Farmer (Capitola, California); Peter Lyle Choyke (Bethesda, Maryland); Peter Pinto (Bethesda, Maryland); Bradford J. Wood (Potomac, Maryland) |
| ASSIGNEE(S) | Koninklijke Philips Electronics N.V. (Eindhoven, Netherlands) |
| INVENTOR(S) | Sheng Xu (Rockville, Maryland); Jochen Kruecker (Washington, District of Columbia); Guy Shechter (Briarcliff Manor, New York); Ian Farmer (Capitola, California); Peter Lyle Choyke (Bethesda, Maryland); Peter Pinto (Bethesda, Maryland); Bradford J. Wood (Potomac, Maryland) |
| ABSTRACT | A method and system for performing biopsies can include an imaging system for obtaining diagnostic images of a target region; a tracking system; a probe having a deployable biopsy needle for performing a biopsy procedure where the tracking system generates tracking information for at least one of the probe and the biopsy needle; an ultrasound imaging system for obtaining ultrasound imaging of the target region; and a computer in communication with the tracking system, the imaging system and the ultrasound imaging system. The computer can register the tracking system with the imaging system. The computer transfers a marking of a biopsy site associated with the biopsy procedure from the ultrasound imaging to the diagnostic images based on the tracking information and the registration of the tracking system with the diagnostic images. |
| FILED | Friday, June 12, 2009 |
| APPL NO | 12/993854 |
| ART UNIT | 3768 — Optics |
| CURRENT CPC | Surgery 6/429 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447385 | Sterzer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fred Sterzer (Princeton, New Jersey); Daniel D. Mawhinney (Livingston, New Jersey); Laleh Rabieirad (Ithaca, New York); David E. Quinn (Auburn, New York); John A. Lane (Weedsport, New York); Matthew D. Mullin (Memphis, New York); Charles N. Stewart (Skaneateles, New York) |
| ASSIGNEE(S) | Welch Allyn, Inc. (Skaneateles Falls, New York) |
| INVENTOR(S) | Fred Sterzer (Princeton, New Jersey); Daniel D. Mawhinney (Livingston, New Jersey); Laleh Rabieirad (Ithaca, New York); David E. Quinn (Auburn, New York); John A. Lane (Weedsport, New York); Matthew D. Mullin (Memphis, New York); Charles N. Stewart (Skaneateles, New York) |
| ABSTRACT | A microwave handheld radiometer for measuring subsurface tissue temperature of a subject includes a microwave antenna disposed relative to a handheld radiometer housing and adapted to electromagnetically couple to a skin surface of a subject, a circulator having a first circulator input and a second circulator input, wherein the first circulator input is electrically coupled to said antenna via a microwave feedline. A switch is electrically disposed between the antenna and an microwave feedline, said switch having a calibrate state and a measure state. A noise source, electrically coupled to the circulator, is being configured to provide a first source of thermal noise at a first temperature and a second source of thermal noise at a second temperature, wherein the noise source is switched between the first source and second source upon external command wherein a detector provides an output wherein surface temperature effects are corrected for the sub-surface measurement. |
| FILED | Wednesday, July 28, 2010 |
| APPL NO | 12/845447 |
| ART UNIT | 3768 — Optics |
| CURRENT CPC | Surgery 6/430 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447407 | Talathi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sachin S. Talathi (Gainesville, Florida); Dong-Uk Hwang (Daejeon, South Korea); William L. Ditto (Scottsdale, Arizona); Paul R. Carney (Gainesville, Florida); Mark Spano (Scottsdale, Arizona) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Sachin S. Talathi (Gainesville, Florida); Dong-Uk Hwang (Daejeon, South Korea); William L. Ditto (Scottsdale, Arizona); Paul R. Carney (Gainesville, Florida); Mark Spano (Scottsdale, Arizona) |
| ABSTRACT | Neuronal excitation and inhibition of the brain is tracked in the hippocampal CA1 network during a latent period, wherein biomarkers are observed which include a sustained increase in the firing rate of the excitatory postsynaptic field activity, paired with a subsequent decrease in the firing rate of the inhibitory postsynaptic field activity; the mean amplitude profiles of both fEPSP and fEPSP field potential activity during the latent period have characteristic shapes; both excitatory and inhibitory CA1 field activity firing rates are observed to follow a circadian rhythm that drifts during epileptogenesis; the circadian rhythms described are in-phase in controls and anti-phase during epileptogenesis; and the fEPSP rate drifts from a circadian rhythm to a greater extent than the fEPSP rate. An additional biomarker is a change in a circadian rhythm of core body temperature. Therapeutic measures can include thermal, chemical, or electrical modulation, in an open or closed loop process. |
| FILED | Monday, November 01, 2010 |
| APPL NO | 12/917321 |
| ART UNIT | 3766 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447410 | Greenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. Greenberg (Los Angeles, California); Mark S. Humayun (Glendale, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert J. Greenberg (Los Angeles, California); Mark S. Humayun (Glendale, California) |
| ABSTRACT | Applicant has proposed a combination of the subretinal and epiretinal methods by placing the electronics external to the eye, entering the eye through the pars plana and the piercing the retina (retinotomy) from inside the eye to stimulate subreintally. The present invention is an improved electrode array for subretinal stimulation. A hard polymer such as polyimide is biocompatible and strong for supporting an electrode array and supporting traces in a thin flex circuit array. In the present invention applicant takes advantage of the sharp nature of thin polyimide making a point on the end of the electrode array. This allows the flexible circuit electrode array to be both electrode array and surgical tool to cut the retinal and slide the array under the retina in a single action. |
| FILED | Thursday, October 25, 2007 |
| APPL NO | 11/924477 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08443539 | Cabahug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric F. Cabahug (Fairfax, Virginia); James S. Dodd (Linden, Virginia); Ben Feldman (Reston, Virginia); Don McLaughlin (Ashburn, Virginia); John Schroeder (Leesburg, Virginia); Hector Tapia (Ashburn, Virginia) |
| ASSIGNEE(S) | Prototype Productions Incorporated Ventures Two, LLC (Ashburn, Virginia) |
| INVENTOR(S) | Eric F. Cabahug (Fairfax, Virginia); James S. Dodd (Linden, Virginia); Ben Feldman (Reston, Virginia); Don McLaughlin (Ashburn, Virginia); John Schroeder (Leesburg, Virginia); Hector Tapia (Ashburn, Virginia) |
| ABSTRACT | A firearm may have a plurality of power-consuming accessories that can be attached to the weapon. In order to reduce the weight of these power-consuming accessories, as well as the proliferation of their batteries, the Weapon Accessory Power Distribution System provides a common power source to power the power-consuming accessories attached to the weapon. One or more powered rails are provided to encircle the barrel of the weapon, to provide a point of mechanical and electrical interconnection for the power-consuming accessories to provide quick connect mounting and dismounting of the power-consuming accessory, absent the use of connectors with their tethering cables, which are susceptible to entanglement. The Weapon Accessory Rail Contacts provide the mechanism to electrically interconnect the power-consuming accessory with the powered rail. |
| FILED | Wednesday, March 30, 2011 |
| APPL NO | 13/075880 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/85 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08443726 | Rastegar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jahangir S. Rastegar (Stony Brook, New York); Richard T. Murray (Patchogue, New York) |
| ASSIGNEE(S) | Omnitek Partners, LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jahangir S. Rastegar (Stony Brook, New York); Richard T. Murray (Patchogue, New York) |
| ABSTRACT | A device for enabling safe/arm functionality in a gravity dropped weapon detachably connected to an airframe where the device includes: an elastic element disposed in a shell of the weapon; a releasable connection between the weapon and the airframe to release one or more of a stored and generated energy in the elastic element; and a piezoelectric member connected to one end of the elastic member for converting the one or more of the stored and generated energy to an electrical energy. The releasable connection can include: a link having a movable connection for movement of the link relative to the shell between a first position constraining the elastic element from movement and a second position releasing the elastic member to generate the electrical energy; and a lanyard for tethering the link to the airframe such that the link is moved to the second position upon the weapon being released from the airframe. |
| FILED | Saturday, January 01, 2011 |
| APPL NO | 12/983301 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444059 | Stimek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher M. Stimek (Fort Worth, Texas); Roger Q. Paulsel (Weatherford, Texas) |
| ASSIGNEE(S) | Williams-Pyro, Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Christopher M. Stimek (Fort Worth, Texas); Roger Q. Paulsel (Weatherford, Texas) |
| ABSTRACT | A method and system for attaching a radio frequency identification (RFID) tag to an ordnance is provided. By tailoring the packaged tag and electronics to accommodate existing ordnance body cavities the integrity of the bomb casing is maintained. Likewise, fin assemblies also remain intact and are mounted in a conventional manner to the tagged ordnance. Numerous ordnance types, to include the mark (MK) 80 series general purpose bombs and equivalents are compatible with the tagging method and system described herein. Set screw mounted tail assemblies of various fin configurations are readily assembled onto the metal body casings of tagged ordnances. A curved dipole antenna provides access to external query signals and transmission of tag locating signals. As described herein, tag antennas can mount between ordnance assembly parts, adding to the ease of retrofitting existing ordnance inventory for a RFID tag localizing system. |
| FILED | Saturday, July 21, 2012 |
| APPL NO | 13/555134 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Registers 235/492 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444078 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Larry C. Brown (Odon, Indiana); Phillip S. Mitchell (Springville, Indiana); Joseph Ringwald (Loogootee, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Larry C. Brown (Odon, Indiana); Phillip S. Mitchell (Springville, Indiana); Joseph Ringwald (Loogootee, Indiana) |
| ABSTRACT | The invention involves a novel configuration for a cable reel and two discs. The discs are disposed on opposite sides of the spool and the two discs are able to spin independently from the spool. |
| FILED | Thursday, November 18, 2010 |
| APPL NO | 12/926448 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Winding, tensioning, or guiding 242/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444082 | Foch |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard J Foch (Upper Marlboro, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Richard J Foch (Upper Marlboro, Maryland) |
| ABSTRACT | An air vehicle can be folded into or unfolded from a compact tubular storage container without assembly or disassembly of the air vehicle. The air vehicle includes a fuselage, two aerodynamic surfaces rotatably mounted on the fuselage along a common axis with at least one pivot mechanism, and at least one spring mechanism configured to deploy the aerodynamic surfaces so they extend outwardly from the body. In a stowed configuration, both aerodynamic surfaces are parallel to the fuselage for stowage of the aircraft in a container. Each aerodynamic surface has a winglet located at an outer edge of the tail portion of the aerodynamic surface, and a rudder on each winglet. The aircraft does not require a vertical stabilizer or rudder system on the fuselage. An outer backward-swept wing portion can be unfolded from the outer edge of each aerodynamic surface to increase the wing aspect ratio. |
| FILED | Thursday, August 19, 2010 |
| APPL NO | 12/859639 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444268 | Hammer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Daniel X. Hammer (Bedford, New Hampshire); R. Daniel Ferguson (Melrose, Massachusetts); Nicusor V. Iftimia (Chelmsford, Massachusetts); Teoman E. Ustun (Malden, Massachusetts) |
| ASSIGNEE(S) | Physical Sciences, Inc. (Andover, Massachusetts) |
| INVENTOR(S) | Daniel X. Hammer (Bedford, New Hampshire); R. Daniel Ferguson (Melrose, Massachusetts); Nicusor V. Iftimia (Chelmsford, Massachusetts); Teoman E. Ustun (Malden, Massachusetts) |
| ABSTRACT | A system provides an optical image of an object. A first module tracks a reference feature of the object. A second module includes a source for an imaging beam, a scanning device to move the imaging beam along a portion of the object and a detection device receives a signal associated with an image of the portion of the object. The first module controls the position of the imaging beam relative to the reference feature to correct for the motion of the object. A third module detects a distortion of the object and compensates for the distortion. |
| FILED | Wednesday, January 19, 2011 |
| APPL NO | 13/009457 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444380 | Ottow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nathan Wesley Ottow (Indianapolis, Indiana); Vance A. Mahan (Martinsville, Indiana); Albert Wong (Fishers, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Nathan Wesley Ottow (Indianapolis, Indiana); Vance A. Mahan (Martinsville, Indiana); Albert Wong (Fishers, Indiana) |
| ABSTRACT | The present invention provides engine case systems for gas turbine engines. Embodiments of the engine case systems include a plurality of ring cases and a tie-bolt case. The ring cases may house blades and vanes for the compressor and/or for the turbine. The ring cases may be stacked in series, and may be clamped together by a tie-bolt case. |
| FILED | Friday, December 18, 2009 |
| APPL NO | 12/642271 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/213.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444568 | Antonelli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lynn T. Antonelli (Cranston, Rhode Island); Candida L. Desjardins (Dartmouth, Massachusetts) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lynn T. Antonelli (Cranston, Rhode Island); Candida L. Desjardins (Dartmouth, Massachusetts) |
| ABSTRACT | The invention as disclosed is a non-contact method and apparatus for continuously monitoring a physiological event in a human or animal, such as blood pressure, which involves utilizing a laser-based interferometer system in combination with a laser tracking system and a signal processor to produce a waveform that is representative of a continuous physiological event such as blood pressure or respiration in a subject. |
| FILED | Monday, February 06, 2012 |
| APPL NO | 13/366415 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Surgery 6/485 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444683 | Mahadevan-Jansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anita Mahadevan-Jansen (Nashville, Tennessee); Jonathon D. Wells (Seattle, Washington); E. Duco Jansen (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Anita Mahadevan-Jansen (Nashville, Tennessee); Jonathon D. Wells (Seattle, Washington); E. Duco Jansen (Nashville, Tennessee) |
| ABSTRACT | The present invention, in one aspect, relates to a method for stimulating neural tissue of a living subject. In one embodiment, the method has the steps of generating at least one beam of radiation; introducing at least one of one or more chromophores and one or more optical agents to a target neural tissue; and delivering the at least one beam of radiation to the target neural tissue, wherein the at least one beam of radiation is delivered with a radiant exposure that causes a thermal gradient in the target neural tissue, thereby stimulating the target neural tissue. |
| FILED | Tuesday, November 27, 2007 |
| APPL NO | 11/945649 |
| ART UNIT | 3769 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444899 | DeSimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Ginger M. Denison Rothrock (Durham, North Carolina); Paul Resnick (Cary, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Ginger M. Denison Rothrock (Durham, North Carolina); Paul Resnick (Cary, North Carolina) |
| ABSTRACT | Materials and Methods are provided for fabricating microfluidic devices. The materials include low surface energy fluoropolymer compositions having multiple cure functional groups. The materials can include multiple photocurable and/or thermal-curable functional groups such that laminate devices can be fabricated. The materials also substantially do not swell in the presence of hydrocarbon solvents. |
| FILED | Tuesday, April 03, 2012 |
| APPL NO | 13/438431 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445174 | Webster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dean C. Webster (Fargo, North Dakota); Zhigang Chen (Dublin, Ohio) |
| ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
| INVENTOR(S) | Dean C. Webster (Fargo, North Dakota); Zhigang Chen (Dublin, Ohio) |
| ABSTRACT | Disclosed are photo sensitizers that include a polyol moiety covalently bonded to a fused aromatic moiety. Also disclosed is a method for improving UV laser ablation performance of a coating, such as a cationic UV curable coating, by incorporating an oxalyl-containing additive into the cationic UV curable or other coating. Oxalyl-containing sensitizers having the formula Q-O—C(O)—C(O)—O—R1 wherein Q represents a fused aromatic moiety and R1 is an alkyl or aryl group, are also disclosed, as are oxalyl-containing oxetane resins, oxalyl-containing polyester polyols, and cationic UV curable coating formulations that include oxalyl-containing additives. |
| FILED | Monday, January 30, 2012 |
| APPL NO | 13/361507 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/270.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445383 | Hobart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karl D. Hobart (Upper Marlboro, Maryland); Tatyana I Feygelson (Springfield, Virginia); Marko J Tadjer (Virginia Beach, Virginia); Joshua D. Caldwell (Accokeek, Maryland); Kendrick X Liu (Alexandria, Virginia); Francis J. Kub (Arnold, Maryland); Michael A Mastro (Fairfax, Virginia); James E Butler (Huntingtown, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Karl D. Hobart (Upper Marlboro, Maryland); Tatyana I Feygelson (Springfield, Virginia); Marko J Tadjer (Virginia Beach, Virginia); Joshua D. Caldwell (Accokeek, Maryland); Kendrick X Liu (Alexandria, Virginia); Francis J. Kub (Arnold, Maryland); Michael A Mastro (Fairfax, Virginia); James E Butler (Huntingtown, Maryland) |
| ABSTRACT | A heterojunction between thin films of NCD and 4H—SiC was developed. Undoped and B-doped NCDs were deposited on both n− and p− SiC epilayers. I-V measurements on p+ NCD/n− SiC indicated Schottky rectifying behavior with a turn-on voltage of around 0.2 V. The current increased over eight orders of magnitude with an ideality factor of 1.17 at 30° C. Ideal energy-band diagrams suggested a possible conduction mechanism for electron transport from the SiC conduction band to either the valence band or acceptor level of the NCD film. |
| FILED | Friday, September 05, 2008 |
| APPL NO | 12/205652 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/689 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445577 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhiqun Lin (Ames, Iowa); Xinchang Pang (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Zhiqun Lin (Ames, Iowa); Xinchang Pang (Ames, Iowa) |
| ABSTRACT | The present invention relates to polymers, nanomaterials, and methods of making the same. Various embodiments provide an amphiphilic multi-arm copolymer. The copolymer includes a core unit and a plurality of amphiphilic block copolymer arms. Each block copolymer arm is substituted on the core unit. Each block copolymer arm includes at least one hydrophilic homopolymer subunit and at least one hydrophobic homopolymer subunit. In some examples, the copolymer can include a star-like or bottlebrush-like block copolymer, and can include a Janus copolymer. Various embodiments provide a nanomaterial. In some examples, the nanomaterial can include Janus nanomaterials, and can include nanoparticles, nanorods, or nanotubes. The nanomaterial includes the amphiphilic multi-arm copolymer and at least one inorganic precursor. The inorganic precursor can be coordinated to at least one homopolymer subunit of one of the amphiphilic block copolymer arms to form the nanomaterial. Various embodiments also provide methods of making the copolymer and the nanomaterial. |
| FILED | Monday, July 25, 2011 |
| APPL NO | 13/189800 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 524/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08445641 — Nanocomposites of repeat sequence proteins and phyllosilicate clays and their preparation
| US 08445641 | Drummy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence F. Drummy (Huber Heights, Ohio); Joseph C. McAuliffe (Sunnyvale, California); Rajesh R. Naik (Centerville, Ohio); Richard A. Vaia (Beavercreek, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Lawrence F. Drummy (Huber Heights, Ohio); Joseph C. McAuliffe (Sunnyvale, California); Rajesh R. Naik (Centerville, Ohio); Richard A. Vaia (Beavercreek, Ohio) |
| ABSTRACT | Nanocomposites of repeat sequence protein polymers and phyllosilicates demonstrated improved material properties, for example, improved elasticity, and are useful as suture, tissue scaffolding, and biodegradable composite materials. |
| FILED | Tuesday, August 22, 2006 |
| APPL NO | 11/990665 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/353 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445677 | Neamati et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nouri Neamati (Fullerton, California); Jinxia Deng (Portage, Michigan) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Nouri Neamati (Fullerton, California); Jinxia Deng (Portage, Michigan) |
| ABSTRACT | Disclosed are pyrimidyl guanidine derivatives having anticancer activity. The pyimidyl guanidine derivatives have the structure: R1 is a cyclic (1-7 member) or acyclic (1-7 member) aliphatic, aromatic, heterocyclic groups optionally substituted, R2 is a cyclic (3-7 member) aliphatic, aromatic, heterocyclic groups optionally substituted by functional groups and R3 is a cyclic (3-7 member) aliphatic, aromatic, heterocyclic groups. |
| FILED | Thursday, October 22, 2009 |
| APPL NO | 12/604365 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445695 | Lindsey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jonathan S. Lindsey (Raleigh, North Carolina); Robert S. Loewe (Morrisville, North Carolina); Kannan Muthukumaran (Raleigh, North Carolina); Arounaguiry Ambroise (Cary, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina); ZettaCore, Inc. (Englewood, Colorado) |
| INVENTOR(S) | Jonathan S. Lindsey (Raleigh, North Carolina); Robert S. Loewe (Morrisville, North Carolina); Kannan Muthukumaran (Raleigh, North Carolina); Arounaguiry Ambroise (Cary, North Carolina) |
| ABSTRACT | A method of making a phosphono-substituted dipyrromethane comprises reacting an aldehyde or acetal having at least one phosphono group substituted thereon with pyrrole to produce a phosphono-substituted dipyrromethane; and wherein the phosphono is selected from the group consisting of dialkyl phosphono, diaryl phosphono, and dialkylaryl phosphono. Additional methods, intermediates and products are also described. |
| FILED | Wednesday, August 29, 2012 |
| APPL NO | 13/597815 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445773 | Tran |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thanh Nhon Tran (Chantilly, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thanh Nhon Tran (Chantilly, Virginia) |
| ABSTRACT | A thermoelectric generator has a hot side heat exchanger having a silicon carbide (SiC) honeycomb support with a plurality of passages. The passage walls are coated with a pyrophoric solid fuel such as red oxide (Fe2O3) in combination with a silicon (Si) binder. A quantum well thermoelectric device is positioned between the hot side heat exchanger and heat sink. The performance of the thermoelectric generator is comparable to fuel cells. The thermoelectric generator is small and portable. |
| FILED | Thursday, February 25, 2010 |
| APPL NO | 12/712385 |
| ART UNIT | 1758 — Organic Chemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/205 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445813 | Bradley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy Bradley (Loogootee, Indiana); Eric Hillenbrand (Evansville, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Timothy Bradley (Loogootee, Indiana); Eric Hillenbrand (Evansville, Indiana) |
| ABSTRACT | A portable cutting device and related method of use are disclosed. The method may include the steps of providing a laser source and a battery power supply, and housing the laser source and the battery power supply in at least one storage container carried by a user. The method may further include the step of cutting a barrier with optical energy produced by the laser source and delivered by a handheld laser directing device. |
| FILED | Tuesday, August 18, 2009 |
| APPL NO | 12/543276 |
| ART UNIT | 3742 — Electrical Circuits and Systems |
| CURRENT CPC | Electric heating 219/121.720 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445893 | Meric et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Inanc Meric (New York, New York); Kenneth Shepard (Ossining, New York); Noah J. Tremblay (New York, New York); Philip Kim (New York, New York); Colin P. Nuckolls (New York, New York) |
| ASSIGNEE(S) | Trustees of Columbia University in the City of New York (, New York) |
| INVENTOR(S) | Inanc Meric (New York, New York); Kenneth Shepard (Ossining, New York); Noah J. Tremblay (New York, New York); Philip Kim (New York, New York); Colin P. Nuckolls (New York, New York) |
| ABSTRACT | An apparatus or method can include forming a graphene layer including a working surface, forming a polyvinyl alcohol (PVA) layer upon the working surface of the graphene layer, and forming a dielectric layer upon the PVA layer. In an example, the PVA layer can be activated and the dielectric layer can be deposited on an activated portion of the PVA layer. In an example, an electronic device can include such apparatus, such as included as a portion of graphene field-effect transistor (GFET), or one or more other devices. |
| FILED | Monday, July 19, 2010 |
| APPL NO | 12/839095 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445917 | Haney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sarah Kay Haney (Cary, North Carolina); Sei-Hyung Ryu (Cary, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Sarah Kay Haney (Cary, North Carolina); Sei-Hyung Ryu (Cary, North Carolina) |
| ABSTRACT | An electronic device includes a silicon carbide layer having a first conductivity type and having a first surface and a second surface opposite the first surface, and first and second silicon carbide Zener diodes on the silicon carbide layer. Each of the first and second silicon carbide Zener diodes may include a first heavily doped silicon carbide region having a second conductivity type opposite the first conductivity type on the silicon carbide layer, and an ohmic contact on the first heavily doped silicon carbide region. |
| FILED | Friday, March 20, 2009 |
| APPL NO | 12/408167 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/77 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446096 | Larraza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andres Larraza (Prunedale, California); David M. Wolfe (Texarkana, Texas); Jeffrey K. Catterlin (Salinas, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andres Larraza (Prunedale, California); David M. Wolfe (Texarkana, Texas); Jeffrey K. Catterlin (Salinas, California) |
| ABSTRACT | A THz reverse micromagnetron includes a MEMS-based reverse magnetron configuration in which the anode is located at the center of the magnetron surrounded by a cathode ring. Electrons move radially inward in the combined electric and magnetic cross-fields and can reach orbiting angular frequencies in the THz region, even with a magnetic field of the order of 1 T or less. The THz reverse micromagnetron is portable, operates at room temperature, and can be bright. |
| FILED | Thursday, September 30, 2010 |
| APPL NO | 12/894815 |
| ART UNIT | 2821 — Semiconductors/Memory |
| CURRENT CPC | Electric lamp and discharge devices: Systems 315/39.770 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446242 | Harjes |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel I. Harjes (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel I. Harjes (Cambridge, Massachusetts) |
| ABSTRACT | A mechanical linkage exerts a mechanical force on a permanent magnet to substantially counterbalance the magnetic force attracting the permanent magnet to a ferrous target surface. |
| FILED | Wednesday, June 09, 2010 |
| APPL NO | 12/797217 |
| ART UNIT | 2832 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Magnetically operated switches, magnets, and electromagnets 335/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446325 | Tonn |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David A. Tonn (Charlestown, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David A. Tonn (Charlestown, Rhode Island) |
| ABSTRACT | A hybrid cable antenna includes a first cable antenna that is buoyant and unloaded for operation in a lower portion of the high frequency band. At least one second cable antenna is serially and electrically coupled to the first cable antenna. Each second cable antenna is buoyant and loaded for operation in a portion of the high frequency band that is above the lower portion of the high frequency band. |
| FILED | Monday, May 17, 2010 |
| APPL NO | 12/781147 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Communications: Radio wave antennas 343/709 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446439 | Brothers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy J. Brothers (Ridgecrest, California); Ronald N. Prusia (Ridgecrest, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Timothy J. Brothers (Ridgecrest, California); Ronald N. Prusia (Ridgecrest, California) |
| ABSTRACT | An apparatus and method for performing BLOB analysis. BLOB analysis generally encompasses image processing techniques designed to classify data into BLOBs and calculate statistics for each BLOB. |
| FILED | Thursday, August 06, 2009 |
| APPL NO | 12/536882 |
| ART UNIT | 2697 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/694 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446590 | Sanders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Glen A. Sanders (Scottsdale, Arizona); John Feth (Phoenix, Arizona); Lee K. Strandjord (Tonka Bay, Minnesota); Tiequn Qiu (Glendale, Arizona) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Glen A. Sanders (Scottsdale, Arizona); John Feth (Phoenix, Arizona); Lee K. Strandjord (Tonka Bay, Minnesota); Tiequn Qiu (Glendale, Arizona) |
| ABSTRACT | An optical-fiber filter is provided. The optical-fiber filter includes an optical fiber having a first end-face and an opposing second end-face. The first end-face and the second end-face set a fiber length. The first end-face and the second end-face are coated with reflective coatings. When an optical beam emitted from a laser is coupled into one of the first end-face or the second end-face, an optical beam output from the opposing end-face has a narrow linewidth and low frequency noise fluctuations. |
| FILED | Wednesday, June 01, 2011 |
| APPL NO | 13/150990 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/461 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446743 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ranjan Kumar Gupta (Minneapolis, Minnesota); Krushna Keshab Mohapatra (Minneapolis, Minnesota); Ned Mohan (St. Paul, Minnesota); Gysler Castelino (St. Paul, Minnesota); Kaushik Basu (St. Paul, Minnesota); Nathan Weise (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Ranjan Kumar Gupta (Minneapolis, Minnesota); Krushna Keshab Mohapatra (Minneapolis, Minnesota); Ned Mohan (St. Paul, Minnesota); Gysler Castelino (St. Paul, Minnesota); Kaushik Basu (St. Paul, Minnesota); Nathan Weise (Minneapolis, Minnesota) |
| ABSTRACT | This patent document discloses power electronic transformers having a high-frequency link. An example apparatus include a transformer having a primary winding and a secondary winding, the transformer is configured to receive a primary power signal having a first frequency, a primary converter configured to selectively oscillate polarity of the primary windings with respect to the secondary windings at a second frequency, the second frequency substantially substantially higher than the first frequency, a secondary converter coupled to the secondary winding, the secondary converter configured to provide a load power signal using a high frequency power signal generated using the secondary winding. The secondary converter can be configured to reduce current flow in the primary winding when the polarity of the primary winding is switched, the reduced current follow is configured to reduce disturbances resulting from leakage inductance of the transformer. |
| FILED | Monday, July 12, 2010 |
| APPL NO | 12/834437 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electric power conversion systems 363/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446761 | Apalkov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dmytro Apalkov (San Jose, California); Xueti Tang (Fremont, California); Vladimir Nikitin (Campbell, California); Alexander A. G. Driskill-Smith (Redwood City, California) |
| ASSIGNEE(S) | Grandis, Inc. (San Jose, California) |
| INVENTOR(S) | Dmytro Apalkov (San Jose, California); Xueti Tang (Fremont, California); Vladimir Nikitin (Campbell, California); Alexander A. G. Driskill-Smith (Redwood City, California) |
| ABSTRACT | A method and system for providing a magnetic junction usable in a magnetic device are described. The magnetic junction includes a pinned layer, a plurality of nonmagnetic spacer layers, and a plurality of free layers. The free layers are interleaved with the nonmagnetic spacer layers. A first nonmagnetic spacer layer of the nonmagnetic spacer layers is between the free layers and the pinned layer. Each of the free layers is configured to be switchable between stable magnetic states when a write current is passed through the magnetic junction. Each of the free layers has a critical switching current density. The critical switching current density of one of the free layers changes monotonically from the critical switching current density of an adjacent free layer. The adjacent free layer is between the pinned layer and the one of the plurality of free layers. |
| FILED | Friday, February 18, 2011 |
| APPL NO | 13/031001 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446925 | Goldberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lew Goldberg (Fairfax, Virginia); Brian J Cole (Fairfax Station, Virginia); John E Nettleton (Fairfax Station, Virginia); Dallas N Barr (Woodbridge, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Lew Goldberg (Fairfax, Virginia); Brian J Cole (Fairfax Station, Virginia); John E Nettleton (Fairfax Station, Virginia); Dallas N Barr (Woodbridge, Virginia) |
| ABSTRACT | A method and device for reducing the timing jitter in a passive Q-switched Nd:YAG solid state laser by spatially selective bleaching a thin sheet of a saturable absorber of Cr+4:YAG from a direction orthogonal to the direction of laser emission where the Cr+4:YAG transmission increases 18% when the bleaching probe beam is a single laser diode bar. For steady state operation of a passive Q-switched laser, the pulse-to-pulse timing jitter showed a −12× reduction in standard deviation from 241 nsec for free running operation to 20 nsec with optical triggering. |
| FILED | Friday, January 29, 2010 |
| APPL NO | 12/696096 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447407 | Talathi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sachin S. Talathi (Gainesville, Florida); Dong-Uk Hwang (Daejeon, South Korea); William L. Ditto (Scottsdale, Arizona); Paul R. Carney (Gainesville, Florida); Mark Spano (Scottsdale, Arizona) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Sachin S. Talathi (Gainesville, Florida); Dong-Uk Hwang (Daejeon, South Korea); William L. Ditto (Scottsdale, Arizona); Paul R. Carney (Gainesville, Florida); Mark Spano (Scottsdale, Arizona) |
| ABSTRACT | Neuronal excitation and inhibition of the brain is tracked in the hippocampal CA1 network during a latent period, wherein biomarkers are observed which include a sustained increase in the firing rate of the excitatory postsynaptic field activity, paired with a subsequent decrease in the firing rate of the inhibitory postsynaptic field activity; the mean amplitude profiles of both fEPSP and fEPSP field potential activity during the latent period have characteristic shapes; both excitatory and inhibitory CA1 field activity firing rates are observed to follow a circadian rhythm that drifts during epileptogenesis; the circadian rhythms described are in-phase in controls and anti-phase during epileptogenesis; and the fEPSP rate drifts from a circadian rhythm to a greater extent than the fEPSP rate. An additional biomarker is a change in a circadian rhythm of core body temperature. Therapeutic measures can include thermal, chemical, or electrical modulation, in an open or closed loop process. |
| FILED | Monday, November 01, 2010 |
| APPL NO | 12/917321 |
| ART UNIT | 3766 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447434 | Harris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. Harris (Haslet, Texas); Christopher D. Pylant (Arlington, Texas) |
| ASSIGNEE(S) | Williams-Pyro, Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Robert J. Harris (Haslet, Texas); Christopher D. Pylant (Arlington, Texas) |
| ABSTRACT | A system and method of dynamic distributed control with network topology discovery in an isolated distribution grid is provided. Source modules connect to AC generators and output high voltage DC power on ports. Load modules receive the high voltage DC power on connected ports and convert the DC power to AC power. Loads are connected to AC outlets on load modules. A source module discovers the connected network topology through a series of states following the reading of a configuration file. Each module has a microprocessor. Each microprocessor runs control algorithms using its adjacency map as input. Respective adjacency maps are monitored, compared, and amended as needed to maintain consistency across all adjacency maps, thus ensuring consistent distributed control of the power distribution grid. |
| FILED | Wednesday, January 26, 2011 |
| APPL NO | 13/014712 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/286 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447548 | McKay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anthony L. McKay (Auburn, Washington); Jeremy Popp (Duvall, Washington) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Anthony L. McKay (Auburn, Washington); Jeremy Popp (Duvall, Washington) |
| ABSTRACT | The disclosure provides for a method for identifying and measuring a signal pulse induced in a microcircuit due to ionizing radiation. The method comprises locating an ionizing radiation induced pulse across a microcircuit using a plurality of sensors on the microcircuit. The method further comprises radiating a radiation through the microcircuit to produce a pulse width. The method further comprises using a time to digital converter (TDC) to measure a duration of the pulse width to create a measured pulse width. The method further comprises using the TDC to convert the measured pulse width into a digital signal. |
| FILED | Tuesday, April 07, 2009 |
| APPL NO | 12/419842 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/79 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447563 | Brown |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerry G. Brown (Bloomington, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jerry G. Brown (Bloomington, Indiana) |
| ABSTRACT | A simulation system for predicting a likelihood of whether a target object positioned in an environment will be detected by a detection system when illuminated by a laser source. The simulation system may be used for a laser rangefinder application and a laser designator application. The simulation system may provide a detection probability of the target object at a specified range to the detection system or a plurality of detection probabilities as a function of the range to the detection system. The simulation system may provide an indication of an overlap of the beam provided by the laser source on the target object. The simulation system may determine the effect of vibration on the detection of the target object at a specified range. |
| FILED | Tuesday, March 31, 2009 |
| APPL NO | 12/414769 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/181 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447707 | Massie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Darrell D. Massie (Fort Montgomery, New York); Michael A. Miller (Shreveport, Louisiana); Peter S. Curtiss (Boulder, Colorado) |
| ASSIGNEE(S) | Intelligent Power and Energy Research Corporation (Fort Montgomery, New York) |
| INVENTOR(S) | Darrell D. Massie (Fort Montgomery, New York); Michael A. Miller (Shreveport, Louisiana); Peter S. Curtiss (Boulder, Colorado) |
| ABSTRACT | Automated control of a power network is provided by: providing multiple intelligent power controllers (IPCs) associated with multiple components of the power network, each IPC being associated with a different component; obtaining at least one raw data stream representative of at least one operational aspect of at least one component of the multiple components; and automatically associating, by at least one intelligent power controller associated with at least one component, metadata with the at least one raw data stream to produce at least one self-identifying data stream. The associated metadata describes one or more characteristics of the at least one raw data stream, and the at least one self-identifying data stream facilitates automated creation of predictive process models to assist in automated control of the power network by an IPC manager of the power network. |
| FILED | Thursday, June 17, 2010 |
| APPL NO | 12/817651 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447720 | Rubin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stuart H. Rubin (San Diego, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stuart H. Rubin (San Diego, California) |
| ABSTRACT | A method includes receiving a user-specified context comprising one or more natural language contextual antecedents. Then, for each contextual antecedent, a modified contextual antecedent is created by converting each contextual antecedent to a sequence of integers using a word base. Each modified contextual antecedent is compared to each of a plurality of cases stored in a case base, where each case includes one or more case antecedents and one or more case consequents. The case antecedents and case consequents are stored in the case base as sequences of integers representing the respective case antecedents and case consequents. The case having the case antecedents that best match the contextual antecedents is then selected and the case consequents of the selected case are displayed to a user. The user then provides feedback regarding the displayed case consequents. The feedback may be integrated into the contextual antecedent for a new search of the case base. The method is computer-implementable and may be efficiently performed by a distributed processing system. |
| FILED | Tuesday, April 06, 2010 |
| APPL NO | 12/755268 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/52 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447911 | Burger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Douglas C. Burger (Austin, Texas); Stephen W. Keckler (Austin, Texas); Robert McDonald (Austin, Texas); Lakshminarasimhan Sethumadhavan (Austin, Texas); Franziska Roesner (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, University of Texas System (Austin, Texas) |
| INVENTOR(S) | Douglas C. Burger (Austin, Texas); Stephen W. Keckler (Austin, Texas); Robert McDonald (Austin, Texas); Lakshminarasimhan Sethumadhavan (Austin, Texas); Franziska Roesner (Austin, Texas) |
| ABSTRACT | A method and processor for providing full load/store queue functionality to an unordered load/store queue for a processor with out-of-order execution. Load and store instructions are inserted in a load/store queue in execution order. Each entry in the load/store queue includes an identification corresponding to a program order. Conflict detection in such an unordered load/store queue may be performed by searching a first CAM for all addresses that are the same or overlap with the address of the load or store instruction to be executed. A further search may be performed in a second CAM to identify those entries that are associated with younger or older instructions with respect to the sequence number of the load or store instruction to be executed. The output results of the Address CAM and Age CAM are logically ANDed. |
| FILED | Wednesday, July 02, 2008 |
| APPL NO | 12/166491 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447954 | Jia |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bin Jia (West New York, New Jersey) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Bin Jia (West New York, New Jersey) |
| ABSTRACT | A parallel processing data processing system builds at least one data structure indicating a communication schedule for a plurality of processes each having a respective one of a plurality of equal length vectors formed of multiple equal size chunks. The data processing system, based upon the at least one data structure, communicates chunks of the plurality of vectors among the plurality of processes and performs partial reduction operations on chunks in accordance with the communication schedule. The data processing system then stores a result vector representing reduction of the plurality of vectors. |
| FILED | Friday, September 04, 2009 |
| APPL NO | 12/554074 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448006 | Floyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael S. Floyd (Cedar Park, Texas); Christopher Francois (Shakopee, Minnesota); Naresh Nayar (Rochester, Minnesota); Karthick Rajamani (Austin, Texas); Freeman L. Rawson, III (Austin, Texas); Randal C. Swanberg (Round Rock, Texas); Malcolm S. Ware (Austin, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael S. Floyd (Cedar Park, Texas); Christopher Francois (Shakopee, Minnesota); Naresh Nayar (Rochester, Minnesota); Karthick Rajamani (Austin, Texas); Freeman L. Rawson, III (Austin, Texas); Randal C. Swanberg (Round Rock, Texas); Malcolm S. Ware (Austin, Texas) |
| ABSTRACT | A mechanism is provided for directed resource folding for power management. The mechanism receives a set of static platform characteristics and a set of dynamic platform characteristics for a set of resources associated with the data processing system thereby forming characteristic information. The mechanism determines whether one or more conditions have been met for each resource in the set of resources using the characteristic information. Responsive to the one or more conditions being met, the mechanism performs a resource optimization to determine at least one of a first subset of resources in the set of resources to keep active and a second subset of resources in the set of resources to dynamically fold. Based on the resource optimization, the mechanism performs either a virtual resource optimization to optimally schedule the first subset of resources or a physical resource optimization to dynamically fold the second subset of resources. |
| FILED | Tuesday, October 19, 2010 |
| APPL NO | 12/907190 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448242 | Stolfo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Salvatore J Stolfo (Ridgewood, New Jersey); Ke Wang (New York, New York); Janak Parekh (Manhasset, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Salvatore J Stolfo (Ridgewood, New Jersey); Ke Wang (New York, New York); Janak Parekh (Manhasset, New York) |
| ABSTRACT | Systems, methods, and media for outputting data based on anomaly detection are provided. In some embodiments, methods for outputting data based on anomaly detection include: receiving a known-good dataset; storing distinct n-grams from the known-good dataset to form a binary anomaly detection model; receiving known-good new n-grams; computing a rate of receipt of distinct n-grams in the new n-grams; determining whether further training of the anomaly detection model is necessary based on the rate of receipt on distinct n-grams; using the binary anomaly detection model to determine whether an input dataset contains an anomaly; and outputting the input dataset based on whether the input dataset contains an anomaly. |
| FILED | Wednesday, February 28, 2007 |
| APPL NO | 12/280970 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Information security 726/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08443509 | De Souza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Urban J. De Souza (Rochester Hills, Michigan); Richard M. Kleber (Clarkston, Michigan); Justin Hanson (Dearborn Heights, Michigan); Frederick W. Rhoads (Holly, Michigan); John D. Campbell (Rochester Hills, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Urban J. De Souza (Rochester Hills, Michigan); Richard M. Kleber (Clarkston, Michigan); Justin Hanson (Dearborn Heights, Michigan); Frederick W. Rhoads (Holly, Michigan); John D. Campbell (Rochester Hills, Michigan) |
| ABSTRACT | A method of preparing a plurality of bar-wound stator conductors for electrical interconnection includes inserting the plurality of conductors into a stator, twisting a conductor such that a first conductor of a first row is adjacent to a second conductor of a second row; trimming the adjacent first and second conductors to a common length using a trimming device; and grinding the trimmed first and second conductors to a pre-determined surface profile using a rotary cutting tool. |
| FILED | Wednesday, April 18, 2012 |
| APPL NO | 13/449866 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/596 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08443594 | Prior et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory P. Prior (Birmingham, Michigan); Michael G. Reynolds (Troy, Michigan); Joshua D. Cowgill (Harland, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Gregory P. Prior (Birmingham, Michigan); Michael G. Reynolds (Troy, Michigan); Joshua D. Cowgill (Harland, Michigan) |
| ABSTRACT | A method of controlling the temperature of a thermoelectric generator (TEG) in an exhaust system of an engine is provided. The method includes determining the temperature of the heated side of the TEG, determining exhaust gas flow rate through the TEG, and determining the exhaust gas temperature through the TEG. A rate of change in temperature of the heated side of the TEG is predicted based on the determined temperature, the determined exhaust gas flow rate, and the determined exhaust gas temperature through the TEG. Using the predicted rate of change of temperature of the heated side, exhaust gas flow rate through the TEG is calculated that will result in a maximum temperature of the heated side of the TEG less than a predetermined critical temperature given the predicted rate of change in temperature of the heated side of the TEG. A corresponding apparatus is provided. |
| FILED | Friday, April 02, 2010 |
| APPL NO | 12/753344 |
| ART UNIT | 3748 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Power plants 060/320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08443607 | York et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William D. York (Greer, South Carolina); Willy S. Ziminsky (Simpsonville, South Carolina); Benjamin P. Lacy (Greer, South Carolina) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | William D. York (Greer, South Carolina); Willy S. Ziminsky (Simpsonville, South Carolina); Benjamin P. Lacy (Greer, South Carolina) |
| ABSTRACT | An air/fuel premixer comprising a peripheral wall defining a mixing chamber, a nozzle disposed at least partially within the peripheral wall comprising an outer annular wall spaced from the peripheral wall so as to define an outer air passage between the peripheral wall and the outer annular wall, an inner annular wall disposed at least partially within and spaced from the outer annular wall, so as to define an inner air passage, and at least one fuel gas annulus between the outer annular wall and the inner annular wall, the at least one fuel gas annulus defining at least one fuel gas passage, at least one air inlet for introducing air through the inner air passage and the outer air passage to the mixing chamber, and at least one fuel inlet for injecting fuel through the fuel gas passage to the mixing chamber to form an air/fuel mixture. |
| FILED | Friday, February 20, 2009 |
| APPL NO | 12/389994 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/737 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08443784 | Brennan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel G. Brennan (Brighton, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Daniel G. Brennan (Brighton, Michigan) |
| ABSTRACT | In one exemplary embodiment of the invention an internal combustion engine includes a piston disposed in a cylinder, a valve configured to control flow of air into the cylinder and an actuator coupled to the valve to control a position of the valve. The internal combustion engine also includes a controller coupled to the actuator, wherein the controller is configured to close the valve when an uncontrolled condition for the internal engine is determined. |
| FILED | Thursday, October 06, 2011 |
| APPL NO | 13/267484 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/435 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08443789 | Wu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ko-Jen Wu (Troy, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Ko-Jen Wu (Troy, Michigan) |
| ABSTRACT | An exhaust gas recirculation system for an internal combustion engine comprises an exhaust driven turbocharger having a low pressure turbine outlet in fluid communication with an exhaust gas conduit. The turbocharger also includes a low pressure compressor intake and a high pressure compressor outlet in communication with an intake air conduit. An exhaust gas recirculation conduit fluidly communicates with the exhaust gas conduit to divert a portion of exhaust gas to a low pressure exhaust gas recirculation branch extending between the exhaust gas recirculation conduit and an engine intake system for delivery of exhaust gas thereto. A high pressure exhaust gas recirculation branch extends between the exhaust gas recirculation conduit and the compressor intake and delivers exhaust gas to the compressor for mixing with a compressed intake charge for delivery to the intake system. |
| FILED | Friday, July 23, 2010 |
| APPL NO | 12/842169 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/568.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444045 | Baker |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ian Baker (Etna, New Hampshire) |
| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ian Baker (Etna, New Hampshire) |
| ABSTRACT | A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF). The AMF has a magnetic field strength and frequency suitable for inducing magnetic hysteresis losses in the metal-aluminum powder and is applied for a period that raises temperature of the metal-aluminum powder to an exothermic transformation temperature. At the exothermic transformation temperature, the metal-aluminum powder melts and resolidifies as a metal aluminide solid having a non-magnetic configuration. |
| FILED | Monday, May 07, 2012 |
| APPL NO | 13/465710 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Metal fusion bonding 228/233.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444264 | Kross et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian Kross (Yorktown, Virginia); John (Jack) E. McKisson (Williamsburg, Virginia); John McKisson (Hampton, Virginia); Andrew Weisenberger (Yorktown, Virginia); Wenze Xi (Odenton, Maryland); Carl Zorn (Yorktown, Virginia) |
| ASSIGNEE(S) | Jefferson Science Associates, LLC (Newport News, Virginia) |
| INVENTOR(S) | Brian Kross (Yorktown, Virginia); John (Jack) E. McKisson (Williamsburg, Virginia); John McKisson (Hampton, Virginia); Andrew Weisenberger (Yorktown, Virginia); Wenze Xi (Odenton, Maryland); Carl Zorn (Yorktown, Virginia) |
| ABSTRACT | An upconverting device for enhanced recognition of selected wavelengths is provided. The device comprises a transparent light transmitter in combination with a plurality of upconverting nanoparticles. The device may a lens in eyewear or alternatively a transparent panel such as a window in an instrument or machine. In use the upconverting device is positioned between a light source and the eye(s) of the user of the upconverting device. |
| FILED | Wednesday, April 27, 2011 |
| APPL NO | 13/066898 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 1/06 (20130101) G02C 5/00 (20130101) Original (OR) Class G02C 5/06 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/868 (20130101) Y10S 977/947 (20130101) Y10S 977/951 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444389 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Russell B Jones (Jupiter, Florida); John A Fedock (Port St. Lucie, Florida) |
| ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| INVENTOR(S) | Russell B Jones (Jupiter, Florida); John A Fedock (Port St. Lucie, Florida) |
| ABSTRACT | A multiple piece turbine rotor blade with a shell having an airfoil shape and secured between a spar and a platform with the spar including a tip end piece. a snap ring fits around the spar and abuts against the spar tip end piece on a top side and abuts against a shell on the bottom side so that the centrifugal loads from the shell is passed through the snap ring and into the spar and not through a tip cap dovetail slot and projection structure. |
| FILED | Tuesday, March 30, 2010 |
| APPL NO | 12/749580 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/193.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444846 | Bingham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dennis N. Bingham (Idaho Falls, Idaho); Kerry M. Klingler (Idaho Falls, Idaho); Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Lyman Frost (Midway, Utah) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Dennis N. Bingham (Idaho Falls, Idaho); Kerry M. Klingler (Idaho Falls, Idaho); Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Lyman Frost (Midway, Utah) |
| ABSTRACT | A method of producing hydrogen from sodium hydroxide and water is disclosed. The method comprises separating sodium from a first aqueous sodium hydroxide stream in a sodium ion separator, feeding the sodium produced in the sodium ion separator to a sodium reactor, reacting the sodium in the sodium reactor with water, and producing a second aqueous sodium hydroxide stream and hydrogen. The method may also comprise reusing the second aqueous sodium hydroxide stream by combining the second aqueous sodium hydroxide stream with the first aqueous sodium hydroxide stream. A system of producing hydrogen is also disclosed. |
| FILED | Monday, December 07, 2009 |
| APPL NO | 12/632058 |
| ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/560 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444953 | Miura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michiko Miura (Hampton Bays, New York); Haitao Wu (Rockville, Maryland) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Michiko Miura (Hampton Bays, New York); Haitao Wu (Rockville, Maryland) |
| ABSTRACT | The present invention is directed to low toxicity boronated compounds and methods for their use in the treatment, visualization, and diagnosis of tumors. More specifically, the present invention is directed to low toxicity halogenated, carborane-containing 5,10,15,20-tetraphenylporphyrin compounds and methods for their use particularly in boron neutron capture therapy (BNCT) and photodynamic therapy (PDT) for the treatment of tumors of the brain, head and neck, and surrounding tissue. The invention is also directed to using these halogenated, carborane-containing tetraphenylporphyrin compounds in methods of tumor imaging and/or diagnosis such as MRI, SPECT, or PET. |
| FILED | Thursday, March 22, 2007 |
| APPL NO | 11/689678 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445138 | Lara-Curzio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edgar Lara-Curzio (Lenoir City, Tennessee); Ke An (Knoxville, Tennessee); James O. Kiggans, Jr. (Oak Ridge, Tennessee); Nancy J. Dudney (Knoxville, Tennessee); Cristian I. Contescu (Knoxville, Tennessee); Frederick S. Baker (Oak Ridge, Tennessee); Beth L. Armstrong (Clinton, Tennessee) |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Edgar Lara-Curzio (Lenoir City, Tennessee); Ke An (Knoxville, Tennessee); James O. Kiggans, Jr. (Oak Ridge, Tennessee); Nancy J. Dudney (Knoxville, Tennessee); Cristian I. Contescu (Knoxville, Tennessee); Frederick S. Baker (Oak Ridge, Tennessee); Beth L. Armstrong (Clinton, Tennessee) |
| ABSTRACT | A lightweight, durable lead-acid battery is disclosed. Alternative electrode materials and configurations are used to reduce weight, to increase material utilization and to extend service life. The electrode can include a current collector having a buffer layer in contact with the current collector and an electrochemically active material in contact with the buffer layer. In one form, the buffer layer includes a carbide, and the current collector includes carbon fibers having the buffer layer. The buffer layer can include a carbide and/or a noble metal selected from of gold, silver, tantalum, platinum, palladium and rhodium. When the electrode is to be used in a lead-acid battery, the electrochemically active material is selected from metallic lead (for a negative electrode) or lead peroxide (for a positive electrode). |
| FILED | Tuesday, July 19, 2011 |
| APPL NO | 13/185650 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/233 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445148 | Morse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey D. Morse (Martinez, California); Alan F. Jankowski (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jeffrey D. Morse (Martinez, California); Alan F. Jankowski (Livermore, California) |
| ABSTRACT | A MEMS-based fuel cell package and method thereof is disclosed. The fuel cell package comprises seven layers: (1) a sub-package fuel reservoir interface layer, (2) an anode manifold support layer, (3) a fuel/anode manifold and resistive heater layer, (4) a Thick Film Microporous Flow Host Structure layer containing a fuel cell, (5) an air manifold layer, (6) a cathode manifold support structure layer, and (7) a cap. Fuel cell packages with more than one fuel cell are formed by positioning stacks of these layers in series and/or parallel. The fuel cell package materials such as a molded plastic or a ceramic green tape material can be patterned, aligned and stacked to form three dimensional microfluidic channels that provide electrical feedthroughs from various layers which are bonded together and mechanically support a MEMS-based miniature fuel cell. The package incorporates resistive heating elements to control the temperature of the fuel cell stack. The package is fired to form a bond between the layers and one or more microporous flow host structures containing fuel cells are inserted within the Thick Film Microporous Flow Host Structure layer of the package. |
| FILED | Monday, September 27, 2004 |
| APPL NO | 10/952260 |
| ART UNIT | 1728 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445159 | Tucker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael C. Tucker (Oakland, California); Craig P. Jacobson (Moraga, California); Lutgard C. De Jonghe (Lafayette, California); Steven J. Visco (Berkeley, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Michael C. Tucker (Oakland, California); Craig P. Jacobson (Moraga, California); Lutgard C. De Jonghe (Lafayette, California); Steven J. Visco (Berkeley, California) |
| ABSTRACT | Several members make up a joint in a high-temperature electrochemical device, wherein the various members perform different functions. The joint is useful for joining multiple cells (generally tubular modules) of an electrochemical device to produce a multi-cell segment-in-series stack for a solid oxide fuel cell, for instance. The joint includes sections that bond the joining members to each other; one or more seal sections that provide gas-tightness, and sections providing electrical connection and/or electrical insulation between the various joining members. A suitable joint configuration for an electrochemical device has a metal joint housing, a first porous electrode, a second porous electrode, separated from the first porous electrode by a solid electrolyte, and an insulating member disposed between the metal joint housing and the electrolyte and second electrode. One or more brazes structurally and electrically connects the first electrode to the metal joint housing and forms a gas tight seal between the first electrode and the second electrode. |
| FILED | Monday, November 28, 2005 |
| APPL NO | 11/791270 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/452 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445236 | Hennessey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susan Marie Hennessey (Avondale, Pennsylvania); Julie Friend (Claymond, Delaware); Richard T. Elander (Evergreen, Colorado); Melvin P. Tucker, III (Lakewood, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy LLC (Golden, Colorado); E I du Pont de Nemours and Company (Wilmington, Delaware) |
| INVENTOR(S) | Susan Marie Hennessey (Avondale, Pennsylvania); Julie Friend (Claymond, Delaware); Richard T. Elander (Evergreen, Colorado); Melvin P. Tucker, III (Lakewood, Colorado) |
| ABSTRACT | A method is provided for producing an improved pretreated biomass product for use in saccharification followed by fermentation to produce a target chemical that includes removal of saccharification and or fermentation inhibitors from the pretreated biomass product. Specifically, the pretreated biomass product derived from using the present method has fewer inhibitors of saccharification and/or fermentation without a loss in sugar content. |
| FILED | Wednesday, August 22, 2007 |
| APPL NO | 11/843157 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/72 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445240 | Scharf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael E. Scharf (Battle Ground, Indiana); Drion G. Boucias (Gainesville, Florida); Aurelien Tartar (Cooper City, Florida); Monique R. Coy (Gainville, Florida); Xuguo Zhou (Lexington, Kentucky); Tamer Ibrahim Zaki Salem (East Lansing, Michigan); Sanjay B. Jadhao (Gainesville, Florida); Marsha M. Wheeler (Urbana, Illinois) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Michael E. Scharf (Battle Ground, Indiana); Drion G. Boucias (Gainesville, Florida); Aurelien Tartar (Cooper City, Florida); Monique R. Coy (Gainville, Florida); Xuguo Zhou (Lexington, Kentucky); Tamer Ibrahim Zaki Salem (East Lansing, Michigan); Sanjay B. Jadhao (Gainesville, Florida); Marsha M. Wheeler (Urbana, Illinois) |
| ABSTRACT | The disclosure provides isolated nucleic acid molecules derived from the gut of the termite R flavipes, recombinant nucleic acid molecules comprising a vector and an isolated heterologous nucleic acid molecule operably inserted therein, whereby, when transformed into an appropriate host cell system, the heterologous nucleic acid sequence is expressed as a polypeptide having an activity similar to that when expressed in the gut of the termite R. flavipes. The recombinant nucleic acid molecules can comprise more than one heterologous nucleic acid molecule such that more than one polypeptide may be expressed by the host system. The expressed polypeptides may be substantially purified, or used in a substantially unpurified form, to be admixed with a lignocellulose source to be converted to a fermentable product such as a sugar or a mixture of sugars. One aspect of the present disclosure, therefore, encompasses methods of converting a lignified plant material to a fermentable product, the method comprising obtaining a series of isolated polypeptides of a termite, wherein the series of polypeptides cooperate to convert a plant lignocellulose to a fermentable product; and incubating the series of polypeptides with a source of lignified plant material, under conditions allowing the polypeptides to cooperatively produce a fermentable product from the lignified plant material. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 13/263107 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445388 | Fox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert V. Fox (Idaho Falls, Idaho); Rene G. Rodriguez (Pocatello, Idaho); Joshua Pak (Pocatello, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Robert V. Fox (Idaho Falls, Idaho); Rene G. Rodriguez (Pocatello, Idaho); Joshua Pak (Pocatello, Idaho) |
| ABSTRACT | Single source precursors are subjected to carbon dioxide to form particles of material. The carbon dioxide may be in a supercritical state. Single source precursors also may be subjected to supercritical fluids other than supercritical carbon dioxide to form particles of material. The methods may be used to form nanoparticles. In some embodiments, the methods are used to form chalcopyrite materials. Devices such as, for example, semiconductor devices may be fabricated that include such particles. Methods of forming semiconductor devices include subjecting single source precursors to carbon dioxide to form particles of semiconductor material, and establishing electrical contact between the particles and an electrode. |
| FILED | Monday, May 02, 2011 |
| APPL NO | 13/099043 |
| ART UNIT | 2823 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/704 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445446 | Deiters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Deiters (La Jolla, California); Ashton T. Cropp (Bethesda, Maryland); Jason W. Chin (Cambridge, United Kingdom); Christopher J. Anderson (San Francisco, California); Peter G. Schultz (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Alexander Deiters (La Jolla, California); Ashton T. Cropp (Bethesda, Maryland); Jason W. Chin (Cambridge, United Kingdom); Christopher J. Anderson (San Francisco, California); Peter G. Schultz (La Jolla, California) |
| ABSTRACT | This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. |
| FILED | Thursday, June 23, 2011 |
| APPL NO | 13/135129 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/20.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445632 | Barron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Annelise E. Barron (Palo Alto, California); Ann M. Czyzewski (Grayslake, Illinois); Michelle T. Dohm (Palos Park, Illinois); Tyler M. Miller (Aurora, Colorado); Ronald N. Zuckermann (El Cerrito, California); James A. Patch (Cornwall-on-Hudson, New York); Nathaniel P. Chongsiriwatana (Albuquerque, New Mexico) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Annelise E. Barron (Palo Alto, California); Ann M. Czyzewski (Grayslake, Illinois); Michelle T. Dohm (Palos Park, Illinois); Tyler M. Miller (Aurora, Colorado); Ronald N. Zuckermann (El Cerrito, California); James A. Patch (Cornwall-on-Hudson, New York); Nathaniel P. Chongsiriwatana (Albuquerque, New Mexico) |
| ABSTRACT | Antimicrobial peptoid compounds and related compositions as can be used against bacteria effectively and selectively. |
| FILED | Monday, February 09, 2009 |
| APPL NO | 12/378034 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445772 | Bell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lon E. Bell (Altadena, California); Douglas Todd Crane (Altadena, California) |
| ASSIGNEE(S) | BSST, LLC (Irwindale, California) |
| INVENTOR(S) | Lon E. Bell (Altadena, California); Douglas Todd Crane (Altadena, California) |
| ABSTRACT | A thermoelectric power generator is disclosed for use to generate electrical power from heat, typically waste heat. An intermediate heat transfer loop forms a part of the system to permit added control and adjustability in the system. This allows the thermoelectric power generator to more effectively and efficiently generate power in the face of dynamically varying temperatures and heat flux conditions, such as where the heat source is the exhaust of an automobile, or any other heat source with dynamic temperature and heat flux conditions. |
| FILED | Wednesday, October 14, 2009 |
| APPL NO | 12/579368 |
| ART UNIT | 1756 — Organic Chemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/205 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445838 | Bixler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jay V. Bixler (Lafayette, California); Timothy G. Brandt (Manteca, California); James L. Conger (San Ramon, California); Janice K. Lawson (Tracy, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jay V. Bixler (Lafayette, California); Timothy G. Brandt (Manteca, California); James L. Conger (San Ramon, California); Janice K. Lawson (Tracy, California) |
| ABSTRACT | A method for generating a deselect mapping for a focal plane array according to one embodiment includes gathering a data set for a focal plane array when exposed to light or radiation from a first known target; analyzing the data set for determining which pixels or subpixels of the focal plane array to add to a deselect mapping; adding the pixels or subpixels to the deselect mapping based on the analysis; and storing the deselect mapping. A method for gathering data using a focal plane array according to another embodiment includes deselecting pixels or subpixels based on a deselect mapping; gathering a data set using pixels or subpixels in a focal plane array that are not deselected upon exposure thereof to light or radiation from a target of interest; and outputting the data set. |
| FILED | Wednesday, February 04, 2009 |
| APPL NO | 12/365839 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445859 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhehui Wang (Los Alamos, New Mexico); Christopher Morris (Los Alamos, New Mexico); Jeffrey Darnell Bacon (Santa Fe, New Mexico); Mark F. Makela (Los Alamos, New Mexico); Randy Jay Spaulding (Sante Fe, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Zhehui Wang (Los Alamos, New Mexico); Christopher Morris (Los Alamos, New Mexico); Jeffrey Darnell Bacon (Santa Fe, New Mexico); Mark F. Makela (Los Alamos, New Mexico); Randy Jay Spaulding (Sante Fe, New Mexico) |
| ABSTRACT | High-efficiency neutron detector substrate assemblies comprising a first conductive substrate, wherein a first side of the substrate is in direct contact with a first layer of a powder material comprising 10boron, 10boron carbide or combinations thereof, and wherein a conductive material is in proximity to the first layer of powder material; and processes of making said neutron detector substrate assemblies. |
| FILED | Wednesday, June 09, 2010 |
| APPL NO | 12/797414 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/390.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446117 | Gallegos-Lopez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gabriel Gallegos-Lopez (Lomita, California); Michael H. Kinoshita (Redondo Beach, California); Ray M. Ransom (Big Bear City, California); Milun Perisic (Torrance, California) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Gabriel Gallegos-Lopez (Lomita, California); Michael H. Kinoshita (Redondo Beach, California); Ray M. Ransom (Big Bear City, California); Milun Perisic (Torrance, California) |
| ABSTRACT | Embodiments of the present invention relate to methods, systems and apparatus for controlling operation of a multi-phase machine in a vector controlled motor drive system when the multi-phase machine operates in an overmodulation region. The disclosed embodiments provide a mechanism for adjusting a duty cycle of PWM waveforms so that the correct phase voltage command signals are applied at the angle transitions. This can reduce variations/errors in the phase voltage command signals applied to the multi-phase machine so that phase current may be properly regulated thus reducing current/torque oscillation, which can in turn improve machine efficiency and performance, as well as utilization of the DC voltage source. |
| FILED | Monday, January 03, 2011 |
| APPL NO | 12/983669 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Motive power systems 318/400.290 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446127 | Yazami et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rachid Yazami (Los Angeles, California); Joseph McMenamin (Glendale, California); Yvan Reynier (Grenoble, France); Brent T. Fultz (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Centre National de la Recherche Scientifique (Paris, France) |
| INVENTOR(S) | Rachid Yazami (Los Angeles, California); Joseph McMenamin (Glendale, California); Yvan Reynier (Grenoble, France); Brent T. Fultz (Pasadena, California) |
| ABSTRACT | Described are systems and methods for accurately characterizing thermodynamic and materials properties of electrodes and battery systems and for characterizing the state of health of electrodes and battery systems. Measurement of physical attributes of electrodes and batteries corresponding to thermodynamically stabilized electrode conditions permit determination of thermodynamic parameters, including state functions such as the Gibbs free energy, enthalpy and entropy of electrode/electrochemical cell reactions, that enable prediction of important performance attributes of electrode materials and battery systems, such as energy, power density, current rate, cycle life and state of health. Also provided are systems and methods for charging a battery according to its state of health. |
| FILED | Friday, August 07, 2009 |
| APPL NO | 12/537712 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/132 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446575 | Reu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Phillip L. Reu (Albuquerque, New Mexico); Bruce D. Hansche (Edgewood, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Phillip L. Reu (Albuquerque, New Mexico); Bruce D. Hansche (Edgewood, New Mexico) |
| ABSTRACT | In a Doppler velocimeter, the incoming Doppler-shifted beams are heterodyned to reduce their frequencies into the bandwidth of a digital camera. This permits the digital camera to produce at every sampling interval a complete two-dimensional array of pixel values. This sequence of pixel value arrays provides a velocity image of the target. |
| FILED | Tuesday, November 08, 2005 |
| APPL NO | 11/268943 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optics: Measuring and testing 356/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447148 | Garcia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ernest J. Garcia (Albuquerque, New Mexico); Marc A. Polosky (Tijeras, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Ernest J. Garcia (Albuquerque, New Mexico); Marc A. Polosky (Tijeras, New Mexico) |
| ABSTRACT | An optical switch reliably maintains its on or off state even when subjected to environments where the switch is bumped or otherwise moved. In addition, the optical switch maintains its on or off state indefinitely without requiring external power. External power is used only to transition the switch from one state to the other. The optical switch is configured with a fixed optical fiber and a movable optical fiber. The movable optical fiber is guided by various actuators in conjunction with a latching mechanism that configure the switch in one position that corresponds to the on state and in another position that corresponds to the off state. |
| FILED | Tuesday, March 29, 2011 |
| APPL NO | 13/075004 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447565 | Kallman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey S. Kallman (Pleasanton, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jeffrey S. Kallman (Pleasanton, California) |
| ABSTRACT | In one embodiment, a method includes selecting a subset of rays from a set of all rays to use in an error calculation for a constrained conjugate gradient minimization problem, calculating an approximate error using the subset of rays, and calculating a minimum in a conjugate gradient direction based on the approximate error. In another embodiment, a system includes a processor for executing logic, logic for selecting a subset of rays from a set of all rays to use in an error calculation for a constrained conjugate gradient minimization problem, logic for calculating an approximate error using the subset of rays, and logic for calculating a minimum in a conjugate gradient direction based on the approximate error. In other embodiments, computer program products, methods, and systems are described capable of using approximate error in constrained conjugate gradient minimization problems. |
| FILED | Monday, June 07, 2010 |
| APPL NO | 12/795560 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/182 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447585 | Holzrichter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John F. Holzrichter (Berkeley, California); Greg C. Burnett (Livermore, California); Lawrence C. Ng (Danville, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | John F. Holzrichter (Berkeley, California); Greg C. Burnett (Livermore, California); Lawrence C. Ng (Danville, California) |
| ABSTRACT | A system and method for characterizing, synthesizing, and/or canceling out acoustic signals from inanimate sound sources is disclosed. Propagating wave electromagnetic sensors monitor excitation sources in sound producing systems, such as machines, musical instruments, and various other structures. Acoustical output from these sound producing systems is also monitored. From such information, a transfer function characterizing the sound producing system is generated. From the transfer function, acoustical output from the sound producing system may be synthesized or canceled. The methods disclosed enable accurate calculation of matched transfer functions relating specific excitations to specific acoustical outputs. Knowledge of such signals and functions can be used to effect various sound replication, sound source identification, and sound cancellation applications. |
| FILED | Thursday, September 06, 2007 |
| APPL NO | 11/899653 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447912 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Todd A. Inglett (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Todd A. Inglett (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ABSTRACT | Paging memory from random access memory (‘RAM’) to backing storage in a parallel computer that includes a plurality of compute nodes, including: executing a data processing application on a virtual machine operating system in a virtual machine on a first compute node; providing, by a second compute node, backing storage for the contents of RAM on the first compute node; and swapping, by the virtual machine operating system in the virtual machine on the first compute node, a page of memory from RAM on the first compute node to the backing storage on the second compute node. |
| FILED | Tuesday, September 28, 2010 |
| APPL NO | 12/892226 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447960 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dong Chen (Yorktown Heights, New York); Mark Giampapa (Yorktown Heights, New York); Philip Heidelberger (Yorktown Heights, New York); Martin Ohmacht (Yorktown Heights, New York); David L. Satterfield (Tewksbury, Massachusetts); Burkhard Steinmacher-Burow (Boeblingen, Germany); Krishnan Sugavanam (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dong Chen (Yorktown Heights, New York); Mark Giampapa (Yorktown Heights, New York); Philip Heidelberger (Yorktown Heights, New York); Martin Ohmacht (Yorktown Heights, New York); David L. Satterfield (Tewksbury, Massachusetts); Burkhard Steinmacher-Burow (Boeblingen, Germany); Krishnan Sugavanam (Yorktown Heights, New York) |
| ABSTRACT | A system and method for enhancing performance of a computer which includes a computer system including a data storage device. The computer system includes a program stored in the data storage device and steps of the program are executed by a processer. The processor processes instructions from the program. A wait state in the processor waits for receiving specified data. A thread in the processor has a pause state wherein the processor waits for specified data. A pin in the processor initiates a return to an active state from the pause state for the thread. A logic circuit is external to the processor, and the logic circuit is configured to detect a specified condition. The pin initiates a return to the active state of the thread when the specified condition is detected using the logic circuit. |
| FILED | Friday, January 08, 2010 |
| APPL NO | 12/684860 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/229 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448261 | Passian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ali Passian (Knoxville, Tennessee); Thomas George Thundat (Knoxville, Tennessee); Laurene Tetard (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ali Passian (Knoxville, Tennessee); Thomas George Thundat (Knoxville, Tennessee); Laurene Tetard (Knoxville, Tennessee) |
| ABSTRACT | A method of analyzing a sample that includes applying a first set of energies at a first set of frequencies to a sample and applying, simultaneously with the applying the first set of energies, a second set of energies at a second set of frequencies, wherein the first set of energies and the second set of energies form a multi-mode coupling. The method further includes detecting an effect of the multi-mode coupling. |
| FILED | Wednesday, March 17, 2010 |
| APPL NO | 12/726083 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/37 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08443667 | Trusov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Trusov (Irvine, California); Adam Schofield (Irvine, California); Andrei Shkel (Irvine, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander Trusov (Irvine, California); Adam Schofield (Irvine, California); Andrei Shkel (Irvine, California) |
| ABSTRACT | The current invention is a novel gyroscope design, which yields devices robust to fabrication and environmental variations, allows flexible selection of operational parameters, and provides increased bandwidth with minimized sacrifice in gain regardless of the selected frequency of operation. The gyroscope has a single degree-of-freedom (DOF) drive-mode and a 2-DOF sense-mode. The drive-mode operational frequency and the sense-mode bandwidth can be selected arbitrarily in the proposed design, relaxing the tradeoff between the gain, die size, and detection capacitance. The symmetry of the structure ensures the optimal location of the drive-mode resonance relative to the sense-mode operational region, even in presence of fabrication imperfections. |
| FILED | Thursday, February 12, 2009 |
| APPL NO | 12/918284 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444045 | Baker |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ian Baker (Etna, New Hampshire) |
| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ian Baker (Etna, New Hampshire) |
| ABSTRACT | A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF). The AMF has a magnetic field strength and frequency suitable for inducing magnetic hysteresis losses in the metal-aluminum powder and is applied for a period that raises temperature of the metal-aluminum powder to an exothermic transformation temperature. At the exothermic transformation temperature, the metal-aluminum powder melts and resolidifies as a metal aluminide solid having a non-magnetic configuration. |
| FILED | Monday, May 07, 2012 |
| APPL NO | 13/465710 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Metal fusion bonding 228/233.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444899 | DeSimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Ginger M. Denison Rothrock (Durham, North Carolina); Paul Resnick (Cary, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Ginger M. Denison Rothrock (Durham, North Carolina); Paul Resnick (Cary, North Carolina) |
| ABSTRACT | Materials and Methods are provided for fabricating microfluidic devices. The materials include low surface energy fluoropolymer compositions having multiple cure functional groups. The materials can include multiple photocurable and/or thermal-curable functional groups such that laminate devices can be fabricated. The materials also substantially do not swell in the presence of hydrocarbon solvents. |
| FILED | Tuesday, April 03, 2012 |
| APPL NO | 13/438431 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444937 | Tuli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Atac Tuli (Davis, California); Jan W. Hopmans (Davis, California); Tamir Kamai (Davis, California); Benjamin D. Shaw (Davis, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Atac Tuli (Davis, California); Jan W. Hopmans (Davis, California); Tamir Kamai (Davis, California); Benjamin D. Shaw (Davis, California) |
| ABSTRACT | A method and apparatus for near real-time in-situ soil solution measurements is presented. An outer sleeve is placed in soil where ionic concentrations of organic or inorganic species are to be measured. A porous section connects with the outer sleeve (the porous section initially loaded with distilled water) equilibrates with the solution present in soil pores to form a solution to be measured. The initial distilled water is displaced within the porous section by a removable plunger. After substantial equilibration of the solution to be measured within the apparatus, the plunger is removed and a removable probe replaced. The probe may be an Ion Selective Electrode, or a transflection dip probe. The probe then may be used under computer control for measurement of solution properties. The Ion Selective Electrode may measure nitrate (NO3−) concentrations. The transflection dip probe may be read with spectrometer with an input deuterium light source. |
| FILED | Monday, March 28, 2011 |
| APPL NO | 13/073551 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/535 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445006 | Garcia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrés J. Garcia (Atlanta, Georgia); Catherine D. Reyes (Miami, Florida); Timothy Petrie (Atlanta, Georgia); Zvi Schwartz (Atlanta, Georgia); Barbara Boyan (Atlanta, Georgia); Jenny E. Raynor (E. Sandwich, Georgia); David M. Collard (Atlanta, Georgia); Abigail M. Wojtowicz (Atlanta, Georgia); Robert E. Guldberg (Marietta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Andrés J. Garcia (Atlanta, Georgia); Catherine D. Reyes (Miami, Florida); Timothy Petrie (Atlanta, Georgia); Zvi Schwartz (Atlanta, Georgia); Barbara Boyan (Atlanta, Georgia); Jenny E. Raynor (E. Sandwich, Georgia); David M. Collard (Atlanta, Georgia); Abigail M. Wojtowicz (Atlanta, Georgia); Robert E. Guldberg (Marietta, Georgia) |
| ABSTRACT | Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are provided. The substrates and devices coated with an α2β1 or α5β1 integrin-specific ligand are shown to have greater tissue formation on the surface relative to controls, in particular greater bone formation. |
| FILED | Monday, February 13, 2012 |
| APPL NO | 13/372234 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445188 | Mohseni |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hooman Mohseni (Wilmette, Illinois) |
| ASSIGNEE(S) | National Science Foundation (Arlington, Virginia) |
| INVENTOR(S) | Hooman Mohseni (Wilmette, Illinois) |
| ABSTRACT | A photolithography method of patterning photoresist involves disposing a two-dimensional array of focusing particles of spherical or other shape on the photoresist and illuminating the particles on the photoresist to generate deep, sub-wavelength patterns on the photoresist. When developed, a positive photoresist layer generates a two-dimensional array of micro- or nano-holes on the developed photoresist. When developed, a negative photoresist layer generates a two-dimensional array of micro- or nano-pillars on the developed photoresist. |
| FILED | Monday, September 14, 2009 |
| APPL NO | 12/584897 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445210 | Quake et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen R. Quake (Stanford, California); Todd Thorsen (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Stephen R. Quake (Stanford, California); Todd Thorsen (Pasadena, California) |
| ABSTRACT | A microfluidic device for analyzing and/or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for its use are provided. The device and methods of the invention are useful for sorting particles, e.g. virions. The invention is also useful for high throughput screening, e.g. combinatorial screening. The microfluidic device comprises a main channel and an inlet region in communication with the main channel at a droplet extrusion region. Droplets of solution containing the biological material are deposited into the main channel through the droplet extrusion region. A fluid different from and incompatible with the solution containing the biological material flows through the main channel so that the droplets containing the biological material do not diffuse or mix. Biological material within the droplets can be analyzed and/or sorted by detecting a predetermined characteristic of the biological sample in each droplet and sorting the droplet accordingly. |
| FILED | Wednesday, December 15, 2010 |
| APPL NO | 12/969411 |
| ART UNIT | 1775 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445248 | Tittiger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Claus Tittiger (Reno, Nevada); Gary Blomquist (Sparks, Nevada) |
| ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education on behalf of the University of Nevada, Reno (Reno, Nevada) |
| INVENTOR(S) | Claus Tittiger (Reno, Nevada); Gary Blomquist (Sparks, Nevada) |
| ABSTRACT | The present disclosure relates to oxidative decarbonylase enzymes, methods of making hydrocarbons with such enzymes, hydrocarbons produced therefrom and uses thereof. More particularly, the present disclosure relates to isolated polypeptide sequences that are cytochrome P450 enzymes with oxidative decarbonylase activity and methods of their use to generate hydrocarbon products, such as biofuels. |
| FILED | Tuesday, November 17, 2009 |
| APPL NO | 12/620328 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445475 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karen Brewer (Blacksburg, Virginia); Shawn Swavey (Springboro, Ohio) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Karen Brewer (Blacksburg, Virginia); Shawn Swavey (Springboro, Ohio) |
| ABSTRACT | The invention provides supramolecular metal complexes as DNA cleaving agents. In the complexes, charge is transferred from one light absorbing metal (e.g. Ru or Os) to an electron accepting metal (e.g. Rh) via a bridging π-acceptor ligand. A bioactive metal-to-metal charge transfer state capable of cleaving DNA is thus generated. The complexes function when irradiated with low energy visible light with or without molecular oxygen. |
| FILED | Monday, November 02, 2009 |
| APPL NO | 12/610729 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/184 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445610 | Kwak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yungwan Kwak (Breinigsville, Pennsylvania); Renaud Nicolay (Montrouge, France); Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yungwan Kwak (Breinigsville, Pennsylvania); Renaud Nicolay (Montrouge, France); Krzysztof Matyjaszewski (Pittsburgh, Pennsylvania) |
| ABSTRACT | A transition metal mediated chain transfer agent controlled polymerization process is described. The process combines the advantages of atom transfer radical polymerization (ATRP) and reversible addition fragmentation transfer (RAFT) polymerization. Synthesis of chain transfer agents useful in the disclosed processes is also disclosed. Other improvements on ATRP RAFT processes are also described. |
| FILED | Friday, March 06, 2009 |
| APPL NO | 12/921296 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 526/222 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446592 | Arissian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ladan Arissian (Albuquerque, New Mexico); Jean-Claude Diels (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Ladan Arissian (Albuquerque, New Mexico); Jean-Claude Diels (Albuquerque, New Mexico) |
| ABSTRACT | A Scanning Phase Intracavity Nanoscope as a measurement system can be realized with a reference laser cavity and a sample laser cavity superimposed upon each other to operatively propagate two laser beams. The sample laser cavity is operatively formed by the sample to be measured. A measurement of the sample is based on differences in the reference laser cavity and the sample laser cavity determined from difference in the two laser beams. |
| FILED | Tuesday, August 04, 2009 |
| APPL NO | 12/535509 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/484 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08446657 | Quetschke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Volker M. Quetschke (Brownsville, Texas); Wan Wu (Yorktown, Virginia); Luke Williams (Gainesville, Florida); Muzammil A. Arain (Gainesville, Florida); Rodica Martin (Gainesville, Florida); David Reitze (Gainesville, Florida); David B. Tanner (Gainesville, Florida); Guido Mueller (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Volker M. Quetschke (Brownsville, Texas); Wan Wu (Yorktown, Virginia); Luke Williams (Gainesville, Florida); Muzammil A. Arain (Gainesville, Florida); Rodica Martin (Gainesville, Florida); David Reitze (Gainesville, Florida); David B. Tanner (Gainesville, Florida); Guido Mueller (Gainesville, Florida) |
| ABSTRACT | Embodiments relate to a method and apparatus for producing polarized light, having a modulator crystal, where the modulator crystal incorporates a birefringent electro-optic material. The modulator crystal has an optic axis, a first polarization axis, and a second polarization axis, where the first polarization axis and second polarization axis are each perpendicular to the optic axis and perpendicular to each other. The apparatus can also include an electrode pair, where application of an electric field modulates light passing through the modulator crystal that is polarized along the first polarization axis. Embodiments pertain to a method and apparatus for modulating light. The apparatus incorporates a modulator crystal having an electro-optic material. The device also has at least two electrode pairs, where each electrode pair modulates light passing through the modulator crystal that has a direction of travel that has a component parallel to the optic axis. |
| FILED | Tuesday, August 21, 2012 |
| APPL NO | 13/590383 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/251 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08445240 | Scharf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael E. Scharf (Battle Ground, Indiana); Drion G. Boucias (Gainesville, Florida); Aurelien Tartar (Cooper City, Florida); Monique R. Coy (Gainville, Florida); Xuguo Zhou (Lexington, Kentucky); Tamer Ibrahim Zaki Salem (East Lansing, Michigan); Sanjay B. Jadhao (Gainesville, Florida); Marsha M. Wheeler (Urbana, Illinois) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Michael E. Scharf (Battle Ground, Indiana); Drion G. Boucias (Gainesville, Florida); Aurelien Tartar (Cooper City, Florida); Monique R. Coy (Gainville, Florida); Xuguo Zhou (Lexington, Kentucky); Tamer Ibrahim Zaki Salem (East Lansing, Michigan); Sanjay B. Jadhao (Gainesville, Florida); Marsha M. Wheeler (Urbana, Illinois) |
| ABSTRACT | The disclosure provides isolated nucleic acid molecules derived from the gut of the termite R flavipes, recombinant nucleic acid molecules comprising a vector and an isolated heterologous nucleic acid molecule operably inserted therein, whereby, when transformed into an appropriate host cell system, the heterologous nucleic acid sequence is expressed as a polypeptide having an activity similar to that when expressed in the gut of the termite R. flavipes. The recombinant nucleic acid molecules can comprise more than one heterologous nucleic acid molecule such that more than one polypeptide may be expressed by the host system. The expressed polypeptides may be substantially purified, or used in a substantially unpurified form, to be admixed with a lignocellulose source to be converted to a fermentable product such as a sugar or a mixture of sugars. One aspect of the present disclosure, therefore, encompasses methods of converting a lignified plant material to a fermentable product, the method comprising obtaining a series of isolated polypeptides of a termite, wherein the series of polypeptides cooperate to convert a plant lignocellulose to a fermentable product; and incubating the series of polypeptides with a source of lignified plant material, under conditions allowing the polypeptides to cooperatively produce a fermentable product from the lignified plant material. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 13/263107 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445248 | Tittiger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Claus Tittiger (Reno, Nevada); Gary Blomquist (Sparks, Nevada) |
| ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education on behalf of the University of Nevada, Reno (Reno, Nevada) |
| INVENTOR(S) | Claus Tittiger (Reno, Nevada); Gary Blomquist (Sparks, Nevada) |
| ABSTRACT | The present disclosure relates to oxidative decarbonylase enzymes, methods of making hydrocarbons with such enzymes, hydrocarbons produced therefrom and uses thereof. More particularly, the present disclosure relates to isolated polypeptide sequences that are cytochrome P450 enzymes with oxidative decarbonylase activity and methods of their use to generate hydrocarbon products, such as biofuels. |
| FILED | Tuesday, November 17, 2009 |
| APPL NO | 12/620328 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445253 | Vanotti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matias B. Vanotti (Florence, South Carolina); Ariel A. Szogi (Florence, South Carolina); Thomas F. Ducey (Florence, South Carolina) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Matias B. Vanotti (Florence, South Carolina); Ariel A. Szogi (Florence, South Carolina); Thomas F. Ducey (Florence, South Carolina) |
| ABSTRACT | Compositions of bacteria which are effective for the nitrification of wastewater, particularly at low temperatures, are described. The compositions are comprised of 35 strains or populations of at least partially characterized isolated bacteria. These compositions may be used to treat wastewater contaminated with animal fecal waste and/or ammonia. In use, wastewater is contacted with the bacterial composition of the invention under aerobic conditions and for a period of time effective to oxidize ammonia therein. |
| FILED | Wednesday, July 01, 2009 |
| APPL NO | 12/495958 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445254 | Curtiss, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Roy Curtiss, III (Paradise Valley, Arizona); Shifeng Wang (Tempe, Arizona); Soo-Young Wanda (Chandler, Arizona); Wei Kong (Phoenix, Arizona) |
| ASSIGNEE(S) | The Arizona Board of Regents for and on Behalf of Arizona State University (Tempe, Arizona); The Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Roy Curtiss, III (Paradise Valley, Arizona); Shifeng Wang (Tempe, Arizona); Soo-Young Wanda (Chandler, Arizona); Wei Kong (Phoenix, Arizona) |
| ABSTRACT | The invention relates to compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens of interest. |
| FILED | Tuesday, November 10, 2009 |
| APPL NO | 12/615872 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445642 | Onisko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce C. Onisko (Kensington, California); Christopher J. Silva (Albany, California); Jesus R. Requena (Briom, Spain); John Mark Carter (Richmond, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Bruce C. Onisko (Kensington, California); Christopher J. Silva (Albany, California); Jesus R. Requena (Briom, Spain); John Mark Carter (Richmond, California) |
| ABSTRACT | The invention is directed to methods to distinguish among different protein conformers of the same protein such as proteins which form amyloid deposits. Using the methods of the invention, one or more protein conformers in a sample can be detected, differentiated, and quantitated. An example of a protein which is known to exist in at least two conformations is the normal prion protein (PrPC) and its infectious isoform (PrPSc). The invention provides means to distinguish PrPC from PrPSc and allows quantitation of each individually, even when the conformers are present together in a mixture. Thus, the methods of the invention can provide important tools for human and animal health. |
| FILED | Tuesday, October 14, 2008 |
| APPL NO | 12/251456 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445746 | Bennetzen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey L. Bennetzen (Bogart, Georgia); Ervin D. Nagy (O'Fallon, Missouri) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Jeffrey L. Bennetzen (Bogart, Georgia); Ervin D. Nagy (O'Fallon, Missouri) |
| ABSTRACT | This invention relates generally to useful compositions and methods related to plant site-directed recombination. In particular, the invention relates to novel nucleic acid sequences unique to a portion of the sorghum NBS-LRR region, as well as vectors, seeds, plant parts and plants comprising these sequences. Methods to investigate recombination co-factors, and methods to investigate potential herbicides are within the scope. This invention also relates to fungal pathogens of sorghum, particularly Periconia circinata. |
| FILED | Monday, February 25, 2008 |
| APPL NO | 12/528290 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/267 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447075 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Doyle E. Wilson (Huxley, Iowa); Viren R. Amin (Ames, Iowa) |
| ASSIGNEE(S) | Biotronics, Inc. (Ames, Iowa) |
| INVENTOR(S) | Doyle E. Wilson (Huxley, Iowa); Viren R. Amin (Ames, Iowa) |
| ABSTRACT | Methods, systems and devices are implemented in connection with measuring characteristics of a portion of muscle tissue. Consistent with one such method an ultrasound probe is presented to the portion of muscle tissue. The probe produces a response-provoking signal in the muscle tissue, and the pressure applied between the probe and the portion of muscle tissue is sensed. A resulting signal is used to determine the muscle tissue characteristics based on the pressure being exerted between the probe and the portion. For example, the pressure data is associated with and used to filter the acquisition or use of ultrasound image data. |
| FILED | Tuesday, May 05, 2009 |
| APPL NO | 12/435699 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Image analysis 382/110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08444045 | Baker |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ian Baker (Etna, New Hampshire) |
| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ian Baker (Etna, New Hampshire) |
| ABSTRACT | A method of joining at least two parts includes steps of dispersing a joining material comprising a multi-phase magnetic metal-aluminum powder at an interface between the at least two parts to be joined and applying an alternating magnetic field (AMF). The AMF has a magnetic field strength and frequency suitable for inducing magnetic hysteresis losses in the metal-aluminum powder and is applied for a period that raises temperature of the metal-aluminum powder to an exothermic transformation temperature. At the exothermic transformation temperature, the metal-aluminum powder melts and resolidifies as a metal aluminide solid having a non-magnetic configuration. |
| FILED | Monday, May 07, 2012 |
| APPL NO | 13/465710 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Metal fusion bonding 228/233.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444907 | Ermochkine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Ermochkine (Chapel Hill, North Carolina); Derek Schorzman (Cary, North Carolina); Jacob Sprague (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | Liquidia Technologies, Inc. (Morrisville, North Carolina) |
| INVENTOR(S) | Alexander Ermochkine (Chapel Hill, North Carolina); Derek Schorzman (Cary, North Carolina); Jacob Sprague (Chapel Hill, North Carolina) |
| ABSTRACT | A large area patterned film includes a first patterned area; a second patterned area; and a seam joining the first patterned area and the second patterned area, wherein the seam has a width less than about 20 micrometers. A method for tiling patterned areas includes depositing a predetermined thickness of a curable material; contacting a first portion of the curable material with a mold; curing the first portion of the curable material; removing the mold from the cured first portion of the curable material; contacting a second portion of the curable material with the mold, such that the mold contacts a portion of the cured first portion of the curable material; curing the second portion of the curable material; and removing the mold to yield a seam between the cured first portion of the curable material and the cured second portion of the curable material, wherein the seam has a dimension less than about 20 micrometers. |
| FILED | Thursday, December 03, 2009 |
| APPL NO | 12/630569 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/496 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445788 | Tsotsis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas K. Tsotsis (Orange, California); James P. Huang (Huntington Beach, California); Namsoo P. Kim (Bellevue, Washington); Keith D. Humfeld (Garden Grove, California); William L. Mitchael (Yorba Linda, California); Brad D. Mecham (Lake Stevens, Washington) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Thomas K. Tsotsis (Orange, California); James P. Huang (Huntington Beach, California); Namsoo P. Kim (Bellevue, Washington); Keith D. Humfeld (Garden Grove, California); William L. Mitchael (Yorba Linda, California); Brad D. Mecham (Lake Stevens, Washington) |
| ABSTRACT | A conductive wire includes a metallic wire substrate having a diameter and a surface, and a coating material having a plurality of carbon nanotubes dispersed therein. The coating material is operable to adhere a portion of the carbon nanotubes to the surface of the wire. The coating material has higher specific conductivity than the metallic wire substrate and also has a low contact resistance with the metallic wire substrate. |
| FILED | Monday, May 10, 2010 |
| APPL NO | 12/776877 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Conductors and insulators 174/126.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08445222 | Spinale et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francis G. Spinale (Charleston, South Carolina); Robert E. Stroud (Mt. Pleasant, South Carolina); Michael R. Zile (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC Foundation for Research Development (Charleston, South Carolina) |
| INVENTOR(S) | Francis G. Spinale (Charleston, South Carolina); Robert E. Stroud (Mt. Pleasant, South Carolina); Michael R. Zile (Charleston, South Carolina) |
| ABSTRACT | Disclosed herein are methods of detecting or predicting diastolic heart failure in a subject, comprising identifying a profile of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) from a body fluid of the subject that is associated herein with the existence of likely development of left ventricular dilation (LVD). |
| FILED | Wednesday, July 11, 2007 |
| APPL NO | 12/307985 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445449 | Hefeneider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Department of Veterans Affairs (Washington, District of Columbia); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | The United States of America, as represented by the Department of Veterans Affairs (Washington, District of Columbia); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Steven H. Hefeneider (Portland, Oregon); Sharon L. McCoy (Portland, Oregon) |
| ABSTRACT | Method and peptide for regulating cellular activity includes a panel of synthesized peptides that have biological effects on inhibiting or enhancing cellular activity. Selected peptides can be used as therapy to reduce and/or inhibit, or initiate and/or enhance, an inflammatory response in a subject. |
| FILED | Tuesday, October 23, 2012 |
| APPL NO | 13/658687 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445658 | Ko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert I. Ko (Salvador, Brazil); Mitermayer Galvão Reis (Salvador, Brazil); Julio Henrique Rosa Croda (Salvador, Brazil); Isadora Cristina Siqueira (Salvador, Brazil); David A. Haake (Los Angeles, California); James Matsunaga (Los Angeles, California); Lee W. Riley (Berkeley, California); Michele Barocchi (Los Angeles, California); Tracy Ann Young (Berkeley, California) |
| ASSIGNEE(S) | The United States of America represented by the Department of Veterans Affairs (Washington, District of Columbia); The Regents of the University of California (Oakland, California); Cornell Research Foundation, Inc. (Ithaca, New York); Fundação Oswaldo Cruz Fiocruz (Rio de Janeiro, Brazil) |
| INVENTOR(S) | Albert I. Ko (Salvador, Brazil); Mitermayer Galvão Reis (Salvador, Brazil); Julio Henrique Rosa Croda (Salvador, Brazil); Isadora Cristina Siqueira (Salvador, Brazil); David A. Haake (Los Angeles, California); James Matsunaga (Los Angeles, California); Lee W. Riley (Berkeley, California); Michele Barocchi (Los Angeles, California); Tracy Ann Young (Berkeley, California) |
| ABSTRACT | The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and their use in diagnostic, therapeutic and vaccine applications. According to the present invention, the isolated molecules encoding for BigL1, BigL2 and BigL3 proteins are used for the diagnosis and prevention of infection with Leptospira species that are capable of producing disease in humans and other mammals, including those of veterinary importance. |
| FILED | Friday, June 15, 2012 |
| APPL NO | 13/525157 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08443693 | Ihrke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chris A. Ihrke (Hartland, Michigan); Joshua S. Mehling (League City, Texas); Adam H. Parsons (Tulsa, Oklahoma); Bryan Kristian Griffith (Webster, Texas); Nicolaus A. Radford (League City, Texas); Frank Noble Permenter (Webster, Texas); Donald R. Davis (Brighton, Michigan); Robert O. Ambrose (Houston, Texas); Lucien Q. Junkin (Houston, Texas) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Chris A. Ihrke (Hartland, Michigan); Joshua S. Mehling (League City, Texas); Adam H. Parsons (Tulsa, Oklahoma); Bryan Kristian Griffith (Webster, Texas); Nicolaus A. Radford (League City, Texas); Frank Noble Permenter (Webster, Texas); Donald R. Davis (Brighton, Michigan); Robert O. Ambrose (Houston, Texas); Lucien Q. Junkin (Houston, Texas) |
| ABSTRACT | A rotary actuator assembly is provided for actuation of an upper arm assembly for a dexterous humanoid robot. The upper arm assembly for the humanoid robot includes a plurality of arm support frames each defining an axis. A plurality of rotary actuator assemblies are each mounted to one of the plurality of arm support frames about the respective axes. Each rotary actuator assembly includes a motor mounted about the respective axis, a gear drive rotatably connected to the motor, and a torsion spring. The torsion spring has a spring input that is rotatably connected to an output of the gear drive and a spring output that is connected to an output for the joint. |
| FILED | Thursday, July 19, 2012 |
| APPL NO | 13/552957 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Machine element or mechanism 074/490.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08443694 | Ihrke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chris A. Ihrke (Hartland, Michigan); Joshua S. Mehling (League City, Texas); Adam H. Parsons (Tulsa, Oklahoma); Bryan Kristian Griffith (Webster, Texas); Nicolaus A. Radford (League City, Texas); Frank Noble Permenter (Webster, Texas); Donald R. Davis (Brighton, Michigan); Robert O. Ambrose (Houston, Texas); Lucien Q. Junkin (Houston, Texas) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Chris A. Ihrke (Hartland, Michigan); Joshua S. Mehling (League City, Texas); Adam H. Parsons (Tulsa, Oklahoma); Bryan Kristian Griffith (Webster, Texas); Nicolaus A. Radford (League City, Texas); Frank Noble Permenter (Webster, Texas); Donald R. Davis (Brighton, Michigan); Robert O. Ambrose (Houston, Texas); Lucien Q. Junkin (Houston, Texas) |
| ABSTRACT | A rotary actuator assembly is provided for actuation of an upper arm assembly for a dexterous humanoid robot. The upper arm assembly for the humanoid robot includes a plurality of arm support frames each defining an axis. A plurality of rotary actuator assemblies are each mounted to one of the plurality of arm support frames about the respective axes. Each rotary actuator assembly includes a motor mounted about the respective axis, a gear drive rotatably connected to the motor, and a torsion spring. The torsion spring has a spring input that is rotatably connected to an output of the gear drive and a spring output that is connected to an output for the joint. |
| FILED | Thursday, July 19, 2012 |
| APPL NO | 13/552965 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Machine element or mechanism 074/490.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08447443 | Ryan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John J Ryan (Tehachapi, California); Jason L Speyer (Los Angeles, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John J Ryan (Tehachapi, California); Jason L Speyer (Los Angeles, California) |
| ABSTRACT | A computerized system and method for peak-seeking-control that uses a unique Kalman filter design to optimize a control loop, in real time, to either maximize or minimize a performance function of a physical object (“plant”). The system and method achieves more accurate and efficient peak-seeking-control by using a time-varying Kalman filter to estimate both the performance function gradient (slope) and Hessian (curvature) based on direct position measurements of the plant, and does not rely upon modeling the plant response to persistent excitation. The system and method can be naturally applied in various applications in which plant performance functions have multiple independent parameters, and it does not depend upon frequency separation to distinguish between system dimensions. |
| FILED | Tuesday, February 07, 2012 |
| APPL NO | 13/367990 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08445850 | Thoma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eben Daniel Thoma (Cary, North Carolina); Cary Doman Secrest (Bethesda, Maryland); William A. Mitchell (New Hill, North Carolina); William C. Squier (Angier, North Carolina) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Eben Daniel Thoma (Cary, North Carolina); Cary Doman Secrest (Bethesda, Maryland); William A. Mitchell (New Hill, North Carolina); William C. Squier (Angier, North Carolina) |
| ABSTRACT | Disclosed is an open-path optical sensor. Typically, the optical sensor directs UV radiation from a source assembly to a detector assembly along a monitoring path. The source assembly emits UV radiation corresponding to a signal channel and to a reference channel. The detector assembly detects UV radiation corresponding to the signal channel and to the reference channel. The detector assembly is in communication with a data acquisition system, which compares the intensity of the detected UV radiation corresponding to the signal channel to the intensity of the UV radiation corresponding to the reference channel. |
| FILED | Monday, June 20, 2011 |
| APPL NO | 13/164046 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/339.60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08446165 | McCoy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bart O. McCoy (Rochester, Minnesota); Robert W. Techentin (Rochester, Minnesota); Daniel Schraufnagel (Rochester, Minnesota); Erik S. Daniel (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Bart O. McCoy (Rochester, Minnesota); Robert W. Techentin (Rochester, Minnesota); Daniel Schraufnagel (Rochester, Minnesota); Erik S. Daniel (Rochester, Minnesota) |
| ABSTRACT | A transmission line on a printed wiring board is tested and printed wiring board manufacturing variability is assessed. A response of the transmission line to a signal test pattern is measured. A network including a plurality of components connected by the transmission line is then simulated. The simulated network is based on the measured scattering parameters and virtual models representative of each of the components in the network. A system-level output response of the simulated network to a simulated input signal is analyzed, and the printed wiring board is characterized based on a comparison of the system-level output response to a printed wiring board performance metric threshold. |
| FILED | Monday, December 20, 2010 |
| APPL NO | 12/973525 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/763.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08445449 | Hefeneider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Department of Veterans Affairs (Washington, District of Columbia); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | The United States of America, as represented by the Department of Veterans Affairs (Washington, District of Columbia); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Steven H. Hefeneider (Portland, Oregon); Sharon L. McCoy (Portland, Oregon) |
| ABSTRACT | Method and peptide for regulating cellular activity includes a panel of synthesized peptides that have biological effects on inhibiting or enhancing cellular activity. Selected peptides can be used as therapy to reduce and/or inhibit, or initiate and/or enhance, an inflammatory response in a subject. |
| FILED | Tuesday, October 23, 2012 |
| APPL NO | 13/658687 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08444121 | Hadden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven Hadden (Poeria, Arizona); Paul Buchele (Glendale, Arizona); Jim Boyd (Phoenix, Arizona) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Steven Hadden (Poeria, Arizona); Paul Buchele (Glendale, Arizona); Jim Boyd (Phoenix, Arizona) |
| ABSTRACT | Systems are provided for damping vibrations from a payload. In an embodiment, and by way of example only, the system includes an isolation strut and a gas line. The isolation strut includes a bellows and a piston. The bellows has a first end and a second end, the first end being enclosed, and the second end attached to the piston to define a chamber. The piston includes a damping annulus therethrough having a gas inlet and a gas outlet. The gas inlet provides flow communication to the chamber of the bellows. The gas line is coupled to the isolation strut and is in fluid communication with the gas outlet thereof. The system is hermetically sealed to contain a gas therein. |
| FILED | Monday, March 31, 2008 |
| APPL NO | 12/059933 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Spring devices 267/64.280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444783 | Chapman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert D. Chapman (Ridgecrest, California); Thomas J. Groshens (Ridgecrest, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert D. Chapman (Ridgecrest, California); Thomas J. Groshens (Ridgecrest, California) |
| ABSTRACT | 3,3,7,7-Tetrakis(difluoramino)octahydro-1,5-diazocinium intermediate salts through difluoramination followed by N-denosylation or N-deprotection, which are valuable for use as precursor(s) to HNFX as well as to other members of the rare class of 3,3,7,7-tetrakis(difluoramino)octahydro-1,5-diazocines. |
| FILED | Friday, June 05, 2009 |
| APPL NO | 12/479278 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08444951 | Roychoudhury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Subir Roychoudhury (Madison, Connecticut); Maxim Lyubovsky (Fairfax, Virginia); Curtis Morgan (Ansonia, Connecticut); Joel DesJardins (Vernon, Connecticut); Dennis E. Walsh (Richboro, Pennsylvania) |
| ASSIGNEE(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| INVENTOR(S) | Subir Roychoudhury (Madison, Connecticut); Maxim Lyubovsky (Fairfax, Virginia); Curtis Morgan (Ansonia, Connecticut); Joel DesJardins (Vernon, Connecticut); Dennis E. Walsh (Richboro, Pennsylvania) |
| ABSTRACT | The present invention provides a process and apparatus for the gasification of a liquid fuel and includes providing a supply of a liquid fuel, a supply of oxidant, and a supply of liquid water; atomizing the liquid fuel and mixing it with the oxidant and steam; catalytically reacting the fuel-oxidant-steam mixture in a catalyst bed; initiating the catalytic reaction with an ignition source; positioning a heat exchanger in proximity with the catalyst bed so as to convert the liquid water to steam; and feeding the steam into the catalytic reaction, thereby eliminating the need for a liquid fuel vaporizer. A preferred catalyst bed includes an ultra-short-channel-length metal substrate. |
| FILED | Wednesday, October 06, 2010 |
| APPL NO | 12/924876 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/652 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445425 | Vale, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wylie W. Vale, Jr. (La Jolla, California); Kathy A. Lewis (San Diego, California); Marilyn H. Perrin (La Jolla, California); Koichi S. Kunitake (San Diego, California); Jean E. Rivier (La Jolla, California); Jozsef Gulyas (Julian, California) |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | Wylie W. Vale, Jr. (La Jolla, California); Kathy A. Lewis (San Diego, California); Marilyn H. Perrin (La Jolla, California); Koichi S. Kunitake (San Diego, California); Jean E. Rivier (La Jolla, California); Jozsef Gulyas (Julian, California) |
| ABSTRACT | A search of the public human genome database identified a human EST, GenBank accession number AW293249, which has high homology to known pufferfish urocortin sequences. The full length sequence was amplified from human genomic DNA and sequenced. Sequence homology comparisons of the novel sequence with human urocortin I and urocortin II revealed that the sequence encoded a novel human urocortin, which was designated urocortin III (UcnIII). While urocortin III does not have high affinity for either CRF-R1 or CRF-R2, the affinity for CRF-R2 is greater than the affinity for CRF-R1. Urocortin III is capable stimulating cyclic AMP production in cells expressing CRF-R2α or β. Thus, the affinity is high enough that urocortin III could act as a native agonist of CRF-R2. However, it is also likely that urocortin III is a stronger agonist of a yet to be identified receptor. |
| FILED | Friday, December 16, 2011 |
| APPL NO | 13/328821 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08445436 | Olcese |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Olcese (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | James Olcese (Tallahassee, Florida) |
| ABSTRACT | The invention discloses a pharmaceutical composition containing oxytocin and melatonin in amounts therapeutically effective for inducing labor in a pregnant human patient. Preferably, the oxytocin content is reduced to mitigate unwanted side effects and the melatonin content synergistically enhances the oxytocin's labor-inducing effectiveness. Also disclosed is a pharmaceutical composition for treatment of a pregnant human patient experiencing pre-term labor characterized by early expression of melatonin receptors in myometrial cells, the composition containing one or more agents which interfere with melatonin binding to said receptors. Additionally, the invention includes a method of treatment effective in inducing labor in a pregnant human patient, the method comprising coadministering melatonin and oxytocin to the patient and a method of treating pre-term labor in a pregnant human patient manifesting early expression of melatonin receptors in her myometrial tissues, the method comprising administering to the patient an agent effective in blocking melatonin binding to the receptors. |
| FILED | Wednesday, December 03, 2008 |
| APPL NO | 12/745819 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/11.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 21, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130521.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page