FedInvent™ Patents

Patent Details for Tuesday, June 04, 2013 

This page was updated on Monday, March 27, 2023 at 03:47 AM GMT

Department of Defense (DOD) 

US 08453314 Viscarra et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Alberto F. Viscarra (Torrance, California);  Ethan S. Heinrich (San Pedro, California);  Melvin S. Campbell (Hawthorne, California);  David T. Winslow (Culver City, California);  Kevin C. Rolston (Westchester, California);  Rosalio S. Vidaurri (Los Angeles, California)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Alberto F. Viscarra (Torrance, California);  Ethan S. Heinrich (San Pedro, California);  Melvin S. Campbell (Hawthorne, California);  David T. Winslow (Culver City, California);  Kevin C. Rolston (Westchester, California);  Rosalio S. Vidaurri (Los Angeles, California)
ABSTRACT A process for fabricating an origami formed antenna radiating structure is provided. In one embodiment, the invention relates to a process for precisely fabricating a radio frequency (RF) antenna structure, the process including providing a flexible circuit substrate, forming a plurality of parallel channels in the flexible circuit substrate in a first direction, mounting the flexible substrate to a precision die, pressing the flexible substrate into the precision die using an elastomeric material thereby sandwiching the flexible substrate between the elastomeric material and the precision die, and applying heat to the flexible substrate sandwiched between the elastomeric material and the precision die.
FILED Tuesday, February 07, 2012
APPL NO 13/368248
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453393 Schroth et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Alberto E. Schroth (El Segundo, California);  Jimmy L. Clark (Newhall, California);  Michael Doan (El Monte, California);  David M. La Komski (Long Beach, California);  Shannon O. White (Hudson, Massachusetts);  Stephen E. Smith (Somerville, Massachusetts);  Christopher M. Shaffer (Groton, Massachusetts);  Wilfried Krone-Schmidt (Fullerton, California)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts);  Aspen Aerogels, Inc. (Northborough, Massachusetts)
INVENTOR(S) Alberto E. Schroth (El Segundo, California);  Jimmy L. Clark (Newhall, California);  Michael Doan (El Monte, California);  David M. La Komski (Long Beach, California);  Shannon O. White (Hudson, Massachusetts);  Stephen E. Smith (Somerville, Massachusetts);  Christopher M. Shaffer (Groton, Massachusetts);  Wilfried Krone-Schmidt (Fullerton, California)
ABSTRACT An article includes a piece of encapsulated insulation including an envelope having at least two vents therethrough, a particulate insulation within the envelope, and a porous filter overlying each vent of the envelope. The porous filter has a mesh size no larger that the minimum size of the particles. The article may further include a structure having a structure surface, and the piece of encapsulated insulation overlies and covers at least a portion of the structure surface.
FILED Friday, August 25, 2006
APPL NO 11/511060
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/172
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453398 Atkins et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Robert G. Atkins (Poughkeepsie, New York);  Eric J. McKeever (Poughkeepsie, New York);  Edward J. Seminaro (Milton, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Robert G. Atkins (Poughkeepsie, New York);  Eric J. McKeever (Poughkeepsie, New York);  Edward J. Seminaro (Milton, New York)
ABSTRACT A support system is provided and includes first and second raised floor tiles, a ramp and sheeting. The ramp includes first and second edges and is disposable with the first edge adjacent to the first raised floor tile and the second edge adjacent to the second raised floor tile. The ramp has a substantially similar thickness as the first raised floor tile at the first edge and a different thickness from the second raised floor tile at the second edge. The sheeting is disposable on the second raised floor tile to abut the second edge of the ramp and has a thickness such that a combined thickness of the sheeting and the second raised floor tile is substantially similar to the thickness of the ramp at the second edge.
FILED Thursday, March 29, 2012
APPL NO 13/433733
ART UNIT 3633 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/220.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453427 Gilchrist et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Brian E. Gilchrist (Ann Arbor, Michigan);  Alec D. Gallimore (Ann Arbor, Michigan);  Thomas M. Liu (Ann Arbor, Michigan);  Louis Musinski (Waltham, Massachusetts);  Joanna Mirecki Millunchick (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Brian E. Gilchrist (Ann Arbor, Michigan);  Alec D. Gallimore (Ann Arbor, Michigan);  Thomas M. Liu (Ann Arbor, Michigan);  Louis Musinski (Waltham, Massachusetts);  Joanna Mirecki Millunchick (Ann Arbor, Michigan)
ABSTRACT A nano-particle field extraction system comprising a grid having a plurality of electrodes each defining an electrical field, wherein the grid has a plurality of vias extending therethrough. The system further comprises a reservoir having a generally dry mixture disposed therein, a plurality of particles suspended in the generally dry mixture, a biasing member applying a biasing force to the generally dry mixture in the reservoir, and a sieve electrode system in electrical communication with the grid. The sieve electrode system has a plurality of through-holes extending from the reservoir to the grid, such that the sieve electrode system cooperates with the biasing member to extract at least one particle from the generally dry mixture and into the grid whereby the electrical fields charge and accelerate the particle in the vias.
FILED Tuesday, July 21, 2009
APPL NO 12/506526
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/202
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453456 Jarmon
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) David C. Jarmon (Kensington, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) David C. Jarmon (Kensington, Connecticut)
ABSTRACT An apparatus includes a thermoelectric (TE) device, a gas flow conduit proximate to one side of the thermoelectric device, a plurality of flexible tubes proximate to a second side of the thermoelectric device, and a spring to control contact force between the flexible tubes and the thermoelectric device. The spring comprises a coil spring at least partially circumscribing the gas flow conduit. The thermoelectric device converts a temperature differential between the flexible tubes and the gas flow conduit into electrical energy.
FILED Friday, August 28, 2009
APPL NO 12/550106
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/768
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453512 Sasso et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) Felix T. Sasso (Los Angeles, California);  Walter H. Chung (Rancho Palos Verdes, California);  John A. L. Shishido (Hermosa Beach, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Felix T. Sasso (Los Angeles, California);  Walter H. Chung (Rancho Palos Verdes, California);  John A. L. Shishido (Hermosa Beach, California)
ABSTRACT A shaker for enabling the testing of gyros and/or other devices for performance under realistic 6DOF motions. The shaker may be implemented as a hexapod, comprising a plate and six individually, simultaneously, and real-time controllable strut assemblies that are capable of extending and contracting linearly. The strut assemblies may comprise high-precision, linear electromagnetic actuators. The strut assemblies may also comprise high-precision non-contact sensors to sense the extension/contraction of the strut assemblies along their stroke length. In addition, the strut assemblies may comprise, at each end thereof, stiff, bendable flexures to attain the repeatable and linear motion required. The controller preferably has a control bandwidth of 1000 Hz or more, so that the motion of the plate can be precisely controlled to realize realistic 6DOF motions.
FILED Thursday, June 17, 2010
APPL NO 12/802949
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/668
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453553 Cannon
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Joseph P. Cannon (Lenox, Michigan)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Joseph P. Cannon (Lenox, Michigan)
ABSTRACT A reactive armor that includes a tube having a substantially central longitudinal axis, and at least two force reaction faces that are parallel to the axis; a casing that includes a back, at least two sides, and at least two end blocks; wherein the sides extend away from the back, the blocks are fastened to the sides at edges opposite of the back, and the tube is positioned between the blocks to form a cover to the casing; initiators included between the end blocks and the force reaction faces; a sensor subsystem that detects a threat, wherein the sensor subsystem is coupled to the initiators, and the sensor subsystem generates an initiation signal in response to the detection of the threat; and when the initiators receive the initiation signal, the initiators substantially simultaneously generate a force such that the tube is rotated about the axis to rotationally defeat the threat.
FILED Friday, July 15, 2011
APPL NO 13/183784
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/36.170
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453571 Dutton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Brian Dwayne Dutton (Ridgecrest, California);  John Kevin Kandell (Ridgecrest, California);  Gabriel Henry Soto (Ridgecrest, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brian Dwayne Dutton (Ridgecrest, California);  John Kevin Kandell (Ridgecrest, California);  Gabriel Henry Soto (Ridgecrest, California)
ABSTRACT A multiple warhead fuzing apparatus including first warhead and a second warhead. Operation/detonation of the first and second warheads is controlled using safe and arming logic and an onboard weapon computer that communicates triggering and fire signal parameters to fire signal logic located on the weapon. For a hard target application, the initiation module(s) of each warhead will initiate when commanded by the warhead's fuze after specific criteria has been satisfied, as determined by the fuze programming from the weapon computer. Soft target applications will require the warheads to initiate simultaneously after a delay from impact. The large area target settings will initiate all warheads upon receipt of a fire command from the weapon computer or height of burst sensor.
FILED Friday, September 24, 2010
APPL NO 12/889473
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/206
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453573 McKimm et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Thomas McKimm (Mount Freedom, New Jersey);  Amy Mulvoy (Lafayette, New Jersey);  Nicole Sapp (Newton, New Jersey);  Anthony DiGiacomo (Wayne, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Thomas McKimm (Mount Freedom, New Jersey);  Amy Mulvoy (Lafayette, New Jersey);  Nicole Sapp (Newton, New Jersey);  Anthony DiGiacomo (Wayne, New Jersey)
ABSTRACT A primer adapter allows hand grenade fuzes of different configurations to use the same primer for the ignition of their explosive trains.
FILED Wednesday, June 15, 2011
APPL NO 13/160780
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/487
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453590 Pittman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) John Robert Pittman (Springfield, Virginia);  Robert Charles Truston (Yorktown, Virginia);  Matthew Marcy (Annapolis, Maryland);  Erick Knezek (Lafayette, Louisiana)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John Robert Pittman (Springfield, Virginia);  Robert Charles Truston (Yorktown, Virginia);  Matthew Marcy (Annapolis, Maryland);  Erick Knezek (Lafayette, Louisiana)
ABSTRACT Self-tensioning load-equalizing mooring systems and methods (of mooring a ship) that employ at least one mooring line and at least one counter-weight.
FILED Tuesday, November 29, 2011
APPL NO 13/306334
ART UNIT 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships
114/230.240
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453802 Simpson
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Anthony Simpson (Panama City Beach, Florida)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Anthony Simpson (Panama City Beach, Florida)
ABSTRACT A brake mechanism for a beam trolley on a beam has a body member on the beam trolley adjacent the beam. The body member has a recess and axially aligned bores and a rotatable lateral pin extends through the aligned bores. The lateral pin has a rotatable elongate cam portion extending across the recess, and a brake pad is in the recess adjacent to the beam and abutting the cam portion. A handle is connected to the lateral pin for rotating the pin and the cam portion to displace the brake pad against the beam. The brake pad frictionally secures the beam trolley on the beam and locks the rotatable cam in place. Rounded end portions on opposite ends of the lateral pin and sleeve-like bushings between the axially aligned bores and rounded end portions permit rotation of the cam portion by the handle.
FILED Monday, July 14, 2008
APPL NO 12/220393
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Brakes
188/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454224 Gardner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Warren L. Gardner (Bel Air, Maryland);  Jerold R. Bottiger (Aberdeen, Maryland);  William R. Sayers (Joppa, Maryland);  Leslie I. Williams (Belcamp, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Warren L. Gardner (Bel Air, Maryland);  Jerold R. Bottiger (Aberdeen, Maryland);  William R. Sayers (Joppa, Maryland);  Leslie I. Williams (Belcamp, Maryland)
ABSTRACT A fomite tumbler and method of transferring an agent from a source object to one or more fomites is provided. The tumbler provides reproducible and adjustable experimental determination of agent transfer between objects such as during handling. The inventions provide a unique mechanism for studying the transfer of a biological agent through a public use system such as the United States Postal System.
FILED Monday, November 29, 2010
APPL NO 12/955307
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Agitating
366/228
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454400 Downs, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Edward F. Downs, Jr. (Panama City, Florida)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Edward F. Downs, Jr. (Panama City, Florida)
ABSTRACT An attachment assembly quickly and securely mounts an outboard motor on a boat transom. Side frame members are disposed in a laterally spaced-apart relationship by two interconnected lateral frame members. A laterally extending cam member is rotatably connected to the side frame members and laterally extends the length between the side frame members. A cam rotating mechanism is connected to the cam member to selectively impart its rotational displacement and a lateral inverted-U-shaped transom channel is formed in the side frame members and is disposed adjacent to the cam member. The rotational displacement of the cam member effects an outward displacement of an outer surface of the cam member into the inverted-U-shaped transom channel to compressively engage and secure a transom by the cam member across the entire width of the motor.
FILED Friday, July 22, 2011
APPL NO 13/199514
ART UNIT 3617 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Marine propulsion
440/49
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454892 Rychwalski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Edward M. Rychwalski (Abingdon, Maryland);  Stephen J. Comaty (Belcamp, Maryland);  James A. Genovese (Street, Maryland);  Patrick Nolan (Havre de Grace, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Edward M. Rychwalski (Abingdon, Maryland);  Stephen J. Comaty (Belcamp, Maryland);  James A. Genovese (Street, Maryland);  Patrick Nolan (Havre de Grace, Maryland)
ABSTRACT A chemical agent detection system is provided that includes a fluid sampling collector suitable for the collecting, concentrating, filtering and storing of chemical agents. Preferably a solid phase extraction syringe is coupled to an adaptor via an injection port. The adaptor forms an outer surface of a sample containment reservoir that allows the fluid sampling collector to associate with a chemical agent detector such as the M256A2 chemical agent detector. The inventive chemical agent detection system allows rapid, low level on-site detection of chemical agents such as nerve agents in fluid media.
FILED Friday, October 15, 2010
APPL NO 12/905729
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/68.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455051 Renn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Michael J. Renn (Hudson, Wisconsin);  Bruce H. King (Albuquerque, New Mexico);  Marcelino Essien (Cedar Crest, New Mexico);  Gregory J. Marquez (Albuquerque, New Mexico);  Manampathy G. Giridharan (Mason, Ohio);  Jyh-Cherng Sheu (Hsinchu City, Taiwan)
ASSIGNEE(S) Optomec, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Michael J. Renn (Hudson, Wisconsin);  Bruce H. King (Albuquerque, New Mexico);  Marcelino Essien (Cedar Crest, New Mexico);  Gregory J. Marquez (Albuquerque, New Mexico);  Manampathy G. Giridharan (Mason, Ohio);  Jyh-Cherng Sheu (Hsinchu City, Taiwan)
ABSTRACT Apparatuses and processes for maskless deposition of electronic and biological materials. The process is capable of direct deposition of features with linewidths varying from the micron range up to a fraction of a millimeter, and may be used to deposit features on substrates with damage thresholds near 100° C. Deposition and subsequent processing may be carried out under ambient conditions, eliminating the need for a vacuum atmosphere. The process may also be performed in an inert gas environment. Deposition of and subsequent laser post processing produces linewidths as low as 1 micron, with sub-micron edge definition. The apparatus nozzle has a large working distance—the orifice to substrate distance may be several millimeters—and direct write onto non-planar surfaces is possible.
FILED Wednesday, December 22, 2010
APPL NO 12/976906
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/256
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455137 Benson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Martin H. Benson (Littleton, Colorado);  Bernd J. Neudecker (Littleton, Colorado)
ASSIGNEE(S) ITN Energy Systems, Inc. (Littleton, Colorado)
INVENTOR(S) Martin H. Benson (Littleton, Colorado);  Bernd J. Neudecker (Littleton, Colorado)
ABSTRACT An apparatus for use as a fracture absorption layer, and an apparatus for use as an electrochemical device are taught. The apparatuses of the present invention may be of particular use in the manufacture of thin-film, lightweight, flexible or conformable, electrochemical devices such as batteries, and arrays of such devices. The present invention may provide many advantages including stunting fractures in a first electrochemical layer from propagating in a second electrochemical layer.
FILED Thursday, May 06, 2004
APPL NO 10/840497
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/188
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455174 Kohl et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
National Science Foundation (NSF)
APPLICANT(S) Paul A. Kohl (Atlanta, Georgia);  Sue Ann Bidstrup-Allen (Atlanta, Georgia);  Clifford Lee Henderson (Douglasville, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Paul A. Kohl (Atlanta, Georgia);  Sue Ann Bidstrup-Allen (Atlanta, Georgia);  Clifford Lee Henderson (Douglasville, Georgia)
ABSTRACT Polymers, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary polymer, among others, includes, a photodefinable polymer having a sacrificial polymer and a photoinitiator.
FILED Thursday, October 28, 2010
APPL NO 12/913807
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/270.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455184 Atchley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Daniel H. Atchley (USAF Academy, Colorado);  Craig T. Narasaki (Colorado Springs, Colorado);  John R. Hickman (Helotes, Texas)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Daniel H. Atchley (USAF Academy, Colorado);  Craig T. Narasaki (Colorado Springs, Colorado);  John R. Hickman (Helotes, Texas)
ABSTRACT This novel form of multiplexing allows the user to probe for multiple targets and simultaneously identify a specific target. An example of solutions provided here comprises: providing one or more assay mixes for a number of targets (the number of assay mixes is less than the number of targets); providing a number of reference patterns (each of the reference patterns is associated with one of the targets); contacting each of a number of aliquots with one of the assay mixes; generating a result pattern, based on positive or negative results; and selecting the reference pattern most similar to the result pattern, to thereby detect the target. Differential multiplexing with pattern recognition may involve molecular or immunological techniques to identify one of many indicators of drug use, illness, disease, or medical condition.
FILED Wednesday, April 11, 2007
APPL NO 11/786260
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455265 Whitten et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
Office of Naval Research (ONR)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) David G. Whitten (Albuquerque, New Mexico);  Sireesha Chemburu (Albuquerque, New Mexico);  Thomas Corbitt (Albuquerque, New Mexico);  Linnea Ista (Albuquerque, New Mexico);  Gabriel Lopez (Albuquerque, New Mexico);  Kirk S. Schanze (Gainesville, Florida);  Motokatsu Ogawa (Sherman Oaks, California);  Eunkyung Ji (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) David G. Whitten (Albuquerque, New Mexico);  Sireesha Chemburu (Albuquerque, New Mexico);  Thomas Corbitt (Albuquerque, New Mexico);  Linnea Ista (Albuquerque, New Mexico);  Gabriel Lopez (Albuquerque, New Mexico);  Kirk S. Schanze (Gainesville, Florida);  Motokatsu Ogawa (Sherman Oaks, California);  Eunkyung Ji (Albuquerque, New Mexico)
ABSTRACT A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of the surface grafted CPE, it is advantageous that the substrate is a nanoparticle or microparticle. Surface grafted CPEs are presented that use silica particles as the substrate, where a modified silane coupling agent connects the surface to the CPE by a series of covalent bonds. Two methods of preparing the surface grafted CPEs are presented. One method involves the inclusion of the surface being modified by the coupling agent and condensed with monomers that form the CPE in a grafted state to the substrate. A second method involves the formation of a CPE with terminal groups that are complimentary to functionality that has been placed on the surface of the substrate by reaction with a coupling agent. The surface grafted CPEs are also described for use as biosensors and biocides.
FILED Friday, February 29, 2008
APPL NO 12/529390
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/527
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455455 Robbins et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Marjorie Robbins (Vancouver, Canada);  Susan de Jong (Vancouver, Canada);  Vandana Sood (Vancouver, Canada);  Lisa E. Hensley (Frederick, Maryland);  Ian MacLachlan (Mission, Canada)
ASSIGNEE(S) Protiva Biotherapeutics, Inc. (Burnaby, BC, Canada);  The United States Army Medical Research and Materiel Command (Washington, District of Columbia)
INVENTOR(S) Marjorie Robbins (Vancouver, Canada);  Susan de Jong (Vancouver, Canada);  Vandana Sood (Vancouver, Canada);  Lisa E. Hensley (Frederick, Maryland);  Ian MacLachlan (Mission, Canada)
ABSTRACT The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA (e.g., dsRNA such as siRNA) that target Lassa virus (LASV) or tissue factor (TF) gene expression, lipid particles comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles (e.g., for treating hemorraghic fever).
FILED Thursday, March 31, 2011
APPL NO 13/077856
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455826 Mullins et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Richard N. Mullins (Goleta, California);  Michael L. Brest (Goleta, California);  Kenneth L. McAllister (Goleta, California)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Richard N. Mullins (Goleta, California);  Michael L. Brest (Goleta, California);  Kenneth L. McAllister (Goleta, California)
ABSTRACT According to one embodiment, an optical device includes a variable aperture mechanism configured on a structure having a radiation detector that receives radiation through an aperture of the variable aperture mechanism. The aperture is selectively movable from a first position to a second position in which the aperture has a different size relative to the aperture in the first position. The structure is configured with one or more magnets that function with one or more magnetically permeable members configured on the variable aperture mechanism to hold the variable aperture mechanism in at least one position using a magnetic force between the magnets and magnetically permeable members.
FILED Friday, April 16, 2010
APPL NO 12/762161
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/338.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455972 Maryfield et al.
FUNDED BY
Department of Defense (DOD)
United States Special Operations Command (SOCOM)
APPLICANT(S) Tony Maryfield (Poway, California);  Mahyar Dadkhah (San Diego, California);  Thomas Davidson (Santee, California)
ASSIGNEE(S) Cubic Corporation (San Diego, California)
INVENTOR(S) Tony Maryfield (Poway, California);  Mahyar Dadkhah (San Diego, California);  Thomas Davidson (Santee, California)
ABSTRACT A photodiode is provided according to various embodiments. In some embodiments, the photodiode includes a substrate and an active region. The active region is configured to receive light through the substrate. In such a configuration, the substrate not only participates in the photodiode operation acts as a light filter depending on the substrate material. In some embodiments, the active region may include solder balls that may be used to couple the photodiode to a printed circuit board. In some embodiments, the active region is coupled face-to-face with the printed circuit board.
FILED Monday, August 13, 2012
APPL NO 13/584457
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/460
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US 08456004 Markunas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Justin K. Markunas (Washington, District of Columbia);  Eric F. Schulte (Santa Barbara, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Justin K. Markunas (Washington, District of Columbia);  Eric F. Schulte (Santa Barbara, California)
ABSTRACT A process is disclosed for high density indium bumping of microchips by using an innovative template wafer upon which the bumps are initially fabricated. Once fabricated, these bumps are transferred to the microchip, after which can be hybridized to another microchip. Such a template wafer is reusable, and thus provides an economical way to fabricate indium bumps. Reusability also eliminates nonuniformities in bump shape and size in serial processing of separate microchips, which is not the case for other indium bump fabrication processes. Such a fabrication process provides a way to form relatively tall indium bumps and accomplishes this without the standard thick photoresist liftoff process. The described process can be suitable for bump pitches under 10 microns, and is only limited by the resolution of the photolithography equipment used.
FILED Thursday, March 08, 2012
APPL NO 13/414781
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/737
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456073 Swager et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Timothy M. Swager (Newton, Massachusetts);  Hongwei Gu (Jiangsu Province, China PRC)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Hongwei Gu (Jiangsu Province, China PRC)
ABSTRACT The present invention provides devices comprising an assembly of carbon nanotubes, and related methods. In some cases, the carbon nanotubes may have enhanced alignment. Devices of the invention may comprise features and/or components which may enhance the emission of electrons and may lower the operating voltage of the devices. Using methods described herein, carbon nanotube assemblies may be manufactured rapidly, at low cost, and over a large surface area. Such devices may be useful in display applications such as field emission devices, or other applications requiring high image quality, low power consumption, and stability over a wide temperature range.
FILED Friday, May 29, 2009
APPL NO 12/474415
ART UNIT 2879 — Optics
CURRENT CPC
Electric lamp and discharge devices
313/309
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US 08456086 Eden et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) J. Gary Eden (Champaign, Illinois);  Sung-Jin Park (Champaign, Illinois);  Kwang Soo (Urbana, Illinois);  Andrew J. Price (Savoy, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) J. Gary Eden (Champaign, Illinois);  Sung-Jin Park (Champaign, Illinois);  Kwang Soo (Urbana, Illinois);  Andrew J. Price (Savoy, Illinois)
ABSTRACT An embodiment of the invention IS an array of microcavity plasma devices The array includes a first metal film electrode with a plurality of non-uniform cross-section microcavities therein that are encapsulated in oxide A second electrode is a thin metal foil encapsulated in oxide that is bonded to the first electrode A packaging layer contains gas or vapor in the non-uniform cross-section microcavities To make such device, photoresist is patterned to encapsulate the anodized foil or film except on a top surface at desired positions of microcavities A second anodization or electrochemical etching is conducted to form the non-uniform cross-section sidewall microcavities cavities After removing photoresist and metal oxide, a final anodization lines the walls of the microcavities with metal oxide and fully encapsulates the metal electrodes with metal oxide.
FILED Monday, October 27, 2008
APPL NO 12/682941
ART UNIT 2879 — Optics
CURRENT CPC
Electric lamp and discharge devices
313/584
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456146 Eccher et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Joseph A. Eccher (Rio Rancho, New Mexico);  Thomas Michael Love (Albuquerque, New Mexico)
ASSIGNEE(S) Goodrich Corporation (Charlotte, North Carolina)
INVENTOR(S) Joseph A. Eccher (Rio Rancho, New Mexico);  Thomas Michael Love (Albuquerque, New Mexico)
ABSTRACT Systems and methods for switched mode power amplification are disclosed herein. A circuit is provided comprising an amplifier network, a DC translation stage for receiving input voltage from the amplifier network and for providing an output voltage to a voltage boost circuit, and a feedback network for providing feedback from the voltage boost circuit to the amplifier network.
FILED Thursday, December 16, 2010
APPL NO 12/970430
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Power supply or regulation systems
323/282
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US 08456161 Happer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) William Happer (Princeton, New Jersey);  Kiyoshi Ishikawa (Princeton, New Jersey);  Brian Patton (Princeton, New Jersey);  Yuan-Yu Jau (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) William Happer (Princeton, New Jersey);  Kiyoshi Ishikawa (Princeton, New Jersey);  Brian Patton (Princeton, New Jersey);  Yuan-Yu Jau (Princeton, New Jersey)
ABSTRACT The present invention relates to a method and system for polarizing a solid compound of interest via spin transfer from an optically-pumped alkali vapor. In one embodiment, the method provides a cell which contains a solid compound as well as pure alkali metal and some amount of buffer gas. The cell is heated to vaporize some of the pure alkali. Resonant laser light is passed through the cell to polarize the atomic vapor, a process known as “optical pumping.” Optical pumping can transfer order from photons to atoms, causing a buildup of vapor atoms in one angular momentum state. This vapor polarization is then transferred through the surface of the solid compound in order to polarize the nuclei in the bulk of the compound. This can produce nuclear polarizations in the sample many times larger than the limit set by thermal equilibrium. The method can be used in nuclear magnetic resonance (NMR) or magnetic resonance imaging (MRI).
FILED Wednesday, September 05, 2007
APPL NO 12/439846
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/309
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US 08456240 Doany et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Fuad E. Doany (Katonah, New York);  Alexander V. Rylyakov (Mount Kisco, New York);  Clint L. Schow (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Fuad E. Doany (Katonah, New York);  Alexander V. Rylyakov (Mount Kisco, New York);  Clint L. Schow (Ossining, New York)
ABSTRACT A differential amplifier stage and method for offset cancellation include an amplifier having an input and an output. An internal offset cancellation circuit has an input for receiving a control signal to control offset cancellation in the amplifier. The offset cancellation circuit is integrated with the amplifier but isolated from the input and the output of the amplifier, and, in accordance with its isolation, an impedance of the stage is unaffected by the offset cancellation circuit.
FILED Friday, August 24, 2012
APPL NO 13/594122
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Amplifiers
330/308
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US 08456249 DeNatale et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Jeffrey F. DeNatale (Thousand Oaks, California);  Philip A. Stupar (Oxnard, California);  Yu-Hua Lin (Oak Park, California);  Robert L. Borwick (Thousand Oaks, California);  Alexandros P. Papavasiliou (Thousand Oaks, California)
ASSIGNEE(S) Teledyne Scientific and Imaging, LLC. (Thousand Oaks, California)
INVENTOR(S) Jeffrey F. DeNatale (Thousand Oaks, California);  Philip A. Stupar (Oxnard, California);  Yu-Hua Lin (Oak Park, California);  Robert L. Borwick (Thousand Oaks, California);  Alexandros P. Papavasiliou (Thousand Oaks, California)
ABSTRACT A microscale apparatus includes a microscale rigidized Parylene strap having a reinforcement structure extending from a first side of the strap, a first silicon substrate suspended by the microscale rigidized Parylene strap, the microscale rigidized Parylene strap conformally coupled to the first substrate, and a second substrate conformally coupled to the microscale rigidized Parylene strap to suspend the first silicon substrate through the microscale rigidized Parylene strap.
FILED Wednesday, May 11, 2011
APPL NO 13/105735
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Oscillators
331/94.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456329 Tran et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Nghia Tran (San Diego, California);  Hoa Phan (Escondido, California);  Tu-Anh Ton (San Diego, California);  John D. Rockway (San Diego, California);  Anthony Ton (San Diego, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Nghia Tran (San Diego, California);  Hoa Phan (Escondido, California);  Tu-Anh Ton (San Diego, California);  John D. Rockway (San Diego, California);  Anthony Ton (San Diego, California)
ABSTRACT In one preferred embodiment, an aircraft marshaling wand controller displays aircraft marshaling instructions to a pilot on a video display monitor on-board an aircraft, such as an aircraft on an aircraft carrier. When an aircraft marshal uses arm motion gestures to form aircraft marshaling instructions for the pilot on the aircraft, the wand controller of the present invention senses or detects those gesture motions, and generates digitized command signals representative of those gesture motions made by the aircraft marshal. A wireless transceiver then transmits those digitized command signals to the aircraft for display on the video monitor for viewing by the pilot.
FILED Thursday, June 03, 2010
APPL NO 12/792885
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456345 Baraniuk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Richard G. Baraniuk (Houston, Texas);  Jason N. Laska (Houston, Texas);  Petros T. Boufounos (Boston, Massachusetts);  Mark A. Davenport (Los Altos Hills, California)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Richard G. Baraniuk (Houston, Texas);  Jason N. Laska (Houston, Texas);  Petros T. Boufounos (Boston, Massachusetts);  Mark A. Davenport (Los Altos Hills, California)
ABSTRACT A method for recovering a signal by measuring the signal to produce a plurality of compressive sensing measurements, discarding saturated measurements from the plurality of compressive sensing measurements and reconstructing the signal from remaining measurements from the plurality of compressive sensing measurements. Alternatively, a method for recovering a signal comprising the steps of measuring a signal to produce a plurality of compressive sensing measurements, identifying saturated measurements in the plurality of compressive sensing measurements and reconstructing the signal from the plurality of compressive sensing measurements, wherein the recovered signal is constrained such that magnitudes of values corresponding to the identified saturated measurements are greater than a predetermined value.
FILED Wednesday, February 23, 2011
APPL NO 13/033212
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/155
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456622 Estes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Lee E. Estes (Mattapoisett, Massachusetts);  Lynn T. Antonelli (Cranston, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lee E. Estes (Mattapoisett, Massachusetts);  Lynn T. Antonelli (Cranston, Rhode Island)
ABSTRACT A system for determining spatial coherence, temporal coherence or both of an optical signal includes a fiber bundle containing optical fibers. Optical fiber inputs are arranged in proximate groups having the same number of fibers. The groups can each receive a portion of the optical signal. Each fiber in the group has a gross length that differs from the other fibers, but each group has the same set of different gross lengths. The fibers are joined to a lens which spreads the optical signal and causes interference between portions of the signal. This interference is detected at a detector. A computer joined to the detector can measure spatial and temporal coherence from the interference. Other embodiments feature multiple detectors and reflection along the bundle.
FILED Tuesday, September 28, 2010
APPL NO 12/892317
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/73.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456882 Apalkov et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Dmytro Apalkov (San Jose, California);  Vladimir Nikitin (Campbell, California);  David Druist (Santa Clara, Canada);  Steven M. Watts (Mountain View, California)
ASSIGNEE(S) Grandis, Inc. (San Jose, California)
INVENTOR(S) Dmytro Apalkov (San Jose, California);  Vladimir Nikitin (Campbell, California);  David Druist (Santa Clara, Canada);  Steven M. Watts (Mountain View, California)
ABSTRACT A method and system for providing a magnetic junction usable in a magnetic memory are described. The magnetic junction includes first and second pinned layers, first and second nonmagnetic spacer layers, and a free layer. The first pinned layer has a first pinned layer magnetic moment and is nonmagnetic layer-free. The first nonmagnetic spacer layer resides between the first pinned and free layers. The free layer resides between the first and second nonmagnetic spacer layers. The second pinned layer has a second pinned layer magnetic moment and is nonmagnetic layer-free. The second nonmagnetic spacer layer resides between the free and second pinned layers. The first and second pinned layer magnetic moments are antiferromagnetically coupled and self-pinned. The magnetic junction is configured to allow the free layer to be switched between stable magnetic states when a write current is passed through the magnetic junction.
FILED Thursday, March 08, 2012
APPL NO 13/415261
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/66
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US 08456926 Ong et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Adrian E. Ong (Pleasanton, California);  Vladimir Nitikin (Campbell, California)
ASSIGNEE(S) Grandis, Inc. (Milpitas, California)
INVENTOR(S) Adrian E. Ong (Pleasanton, California);  Vladimir Nitikin (Campbell, California)
ABSTRACT Memory circuit includes; an array, row decoder, column decoder, addressing circuit to receive an address of the data bit, control logic receiving commands and transmitting control signals to memory system blocks, and sensing and write driver circuits coupled to a selected column. A hidden read compare circuit couples between the sensing circuit and write driver, which couples an error flag to the control logic circuit responsive to a comparison between a data bit in the input latch and a data-out read from the memory array. A write error address tag memory is responsive to the error flag and is coupled to the addressing circuit via a bidirectional bus. A data input output circuit having first and second bidirectional buses to transmit and receive said data bit is provided. Write error address tag memory stores the address if the error flag is set and provides the address during a re-write operation.
FILED Tuesday, January 25, 2011
APPL NO 13/013616
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/189.50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456954 Rikoski
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Richard J. Rikoski (Alameda, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Richard J. Rikoski (Alameda, California)
ABSTRACT A method and apparatus that coherently correlates, in either the frequency domain, or the real domain, an image of a terrain with an extant holographic image of the terrain. Strong correlations indicates matches between features common between the two holograms, or a hologram and an image, and location of the strong correlations indicates position of the features relative to the imager (e.g. a sonar aboard a ship, or a radar aboard a helicopter). Correlation information can be used for navigation.
FILED Monday, May 17, 2010
APPL NO 12/802455
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/89 (20130101) Original (OR) Class
G01S 15/8902 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457437 Peterson et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Kevin A. Peterson (Richardson, Texas);  John J. Coogan (Bedford, Texas)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Kevin A. Peterson (Richardson, Texas);  John J. Coogan (Bedford, Texas)
ABSTRACT The system relates to a method for enhancing an image by extracting edge points from a corresponding image and overlaying the edge points on the image to be enhanced. In one aspect of the method, the first image is of a lower resolution than the second image. The method also contemplates enhancing an image taken with a first modality with a second image taken with another modality.
FILED Tuesday, March 23, 2010
APPL NO 12/729822
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/266
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457709 Matthews et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Robert Matthews (San Diego, California);  Neil John McDonald (San Diego, California)
ASSIGNEE(S) Quantum Applied Science and Research, Inc. (San Diego, California)
INVENTOR(S) Robert Matthews (San Diego, California);  Neil John McDonald (San Diego, California)
ABSTRACT A sensor mounting system includes a rigid main body portion defining a housing within which is mounted a compression element. In use, the compression element provides a predetermined biasing force to force a sensor against the skin of a subject. A secondary support structure provides an adjustable biasing force to retain the main body portion against the subject. Alternatively, the main body portion may be mounted to a rigid pod with one or more secondary compression elements, with the pod itself retained against the subject. An interface layer extending from the main body portion provides a cushion to improve the comfort of the subject. The interface layer and sensor interface elements may be in the form of fingers to increase contact of the sensor with a selected portion of the subject.
FILED Thursday, May 22, 2008
APPL NO 12/153659
ART UNIT 3739 — Optics
CURRENT CPC
Surgery
6/383
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US 08457795 Rubin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Stuart Rubin (San Diego, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Stuart Rubin (San Diego, California)
ABSTRACT In one embodiment, the present invention is a retrofit to rapidly transition to existing consumer refrigerator-freezer product lines in order to greatly eliminate wasted energy. This occurs because spurious opening of the system doors allows heat to enter with the deleterious side effect of causing the compressor to cycle on and off. This, in turn, consumes more power than if such duty cycles could be predicted, which would allow for their smoothing. The invention takes advantage of existing sensor technologies and develops a computational framework for their fusion for the prediction of a dependency, which controls operation of the compressor. Instances of a predictive schema are evolved and this approach allows for greater accuracy in less time than would be possible using competing neural network or support vector machine technologies. A novel evolutionary algorithm is included, which is so defined as to allow its execution on a lower-end computer.
FILED Thursday, October 28, 2010
APPL NO 12/913810
ART UNIT 2121 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Generic control systems or specific applications
7/275
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US 08457810 Batla et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Fawwad M. Batla (Yorba Linda, California);  Yiu-Hung M. Ho (Palos Verdes Estates, California)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Fawwad M. Batla (Yorba Linda, California);  Yiu-Hung M. Ho (Palos Verdes Estates, California)
ABSTRACT A method and system for application of a compound steering law for efficient low thrust transfer orbit trajectory for a spacecraft are disclosed. The method involves calculating, with at least one processor, a desired orbit for the spacecraft. The method further involves calculating a velocity change required to achieve an orbit eccentricity and a velocity change required to achieve a semi-major axis, both of which correspond to the desired orbit for the spacecraft. Also, the method involves calculating the direction of the vector sum of the velocity change required to achieve the orbit eccentricity and the velocity change required to achieve the semi-major axis. Further, the method involves firing at least one thruster of the spacecraft in the direction of the vector sum in order to change the current orbit of the spacecraft to the desired orbit for the spacecraft, thereby changing the orbit eccentricity and the semi-major axis simultaneously.
FILED Thursday, April 14, 2011
APPL NO 13/087280
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457829 Huang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Qingfeng Huang (San Jose, California);  Ying Zhang (Cupertino, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Qingfeng Huang (San Jose, California);  Ying Zhang (Cupertino, California)
ABSTRACT A system and method for determining characteristics of a physical environment with simple motion patterns are provided. A plurality of raw orientation readings are received from a simple motion pattern. A distribution of possible wall orientations upon each raw reading is determined. Wall direction is determined as the mean value of the distribution.
FILED Friday, February 19, 2010
APPL NO 12/709413
ART UNIT 2683 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/25
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458114 Vigoda et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Benjamin Vigoda (Winchester, Massachusetts);  William Bradley (Somerville, Massachusetts);  Shawn Hershey (Jamaica Plain, Massachusetts);  Jeffrey Bernstein (Middleton, Massachusetts)
ASSIGNEE(S) Analog Devices, Inc. (Norwood, Massachusetts)
INVENTOR(S) Benjamin Vigoda (Winchester, Massachusetts);  William Bradley (Somerville, Massachusetts);  Shawn Hershey (Jamaica Plain, Massachusetts);  Jeffrey Bernstein (Middleton, Massachusetts)
ABSTRACT Some general aspects relate to systems and methods of analog computation using numerical representation with uncertainty. For example, a specification of a group of variables is accepted, with each variable having a set of at least N possible values. The group of variables satisfies a set of one or more constraints, and each variable is specified as a decomposition into a group of constituents, with each constituent having a set of M (e.g., M<N) possible constituent values that can be determined based on the variable values. The method also includes forming a specification for configuring a computing device that implements a network representation of the constraints based on the specification of the group of variables. The network representation includes a first set of nodes corresponding to the groups of constituents, a second set of nodes corresponding to the set of constraints, and interconnections between the first and the second sets of nodes for passing continuous-valued data.
FILED Tuesday, March 02, 2010
APPL NO 12/716155
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Artificial intelligence
76/52
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US 08458166 Bent et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Graham A. Bent (Southampton, United Kingdom);  Patrick Dantressangle (Ford, United Kingdom);  David R. Vyvyan (Southampton, United Kingdom)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Graham A. Bent (Southampton, United Kingdom);  Patrick Dantressangle (Ford, United Kingdom);  David R. Vyvyan (Southampton, United Kingdom)
ABSTRACT A database query is received including a logical table identifier at a distributed database node within a distributed network of databases. The logical table identifier includes a dynamically-updatable constant column identifier. Local logical table definitions are filtered based upon the logical table identifier and the dynamically-updatable constant column identifier to identify a local logical table associated with the logical table identifier and the dynamically-updatable constant column identifier. A local query response is formed including data retrieved from a local physical database table mapped by the local logical table in response to identifying the local logical table associated with the logical table identifier and the dynamically-updatable constant column identifier. The database query is responded to, in response to forming the local query response, with at least the local query response. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
FILED Thursday, October 09, 2008
APPL NO 12/248241
ART UNIT 2199 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Database and file management or data structures
77/713
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US 08458208 Vyvyan
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) David R. Vyvyan (Southampton, United Kingdom)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David R. Vyvyan (Southampton, United Kingdom)
ABSTRACT A database query is received including a logical table identifier, a data element, and at least one data source assurance indicator at a distributed database node within a distributed network of databases. The data element is encrypted based upon the at least one data source assurance indicator. A data portion of a local query response to the database query is formed including data retrieved from a local physical database table mapped by a local logical table that matches the received logical table identifier. A node identifier and the encrypted data element are added as an authentication portion of the local query response to authenticate the data portion of the local query response. The database query is responded to with at least the authenticated local query response. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
FILED Thursday, October 09, 2008
APPL NO 12/248109
ART UNIT 2158 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/769
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US 08458259 Karger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) David Karger (Cambridge, Massachusetts);  Eric Lehman (Cambridge, Massachusetts);  F. Thomson Leighton (Newtonville, Massachusetts);  Matthew Levine (Somerville, Massachusetts);  Daniel Lewin (Cambridge, Massachusetts);  Rina Panagrahy (Mountain View, California)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David Karger (Cambridge, Massachusetts);  Eric Lehman (Cambridge, Massachusetts);  F. Thomson Leighton (Newtonville, Massachusetts);  Matthew Levine (Somerville, Massachusetts);  Daniel Lewin (Cambridge, Massachusetts);  Rina Panagrahy (Mountain View, California)
ABSTRACT The invention relates to an apparatus for responding to data requests made by a client. The apparatus includes an input receiving a first data request that includes a sequence of nodes corresponding to a sequence of servers. The apparatus also includes decision logic determining whether the data specified in the data request is available on a selected server, and if the data is not available determining a next node from the sequence of nodes. The apparatus also includes a mapper mapping a server to the next node, and an output requesting the data by transmitting a second data request to the server mapped to the next node.
FILED Friday, December 23, 2011
APPL NO 13/336745
ART UNIT 2452 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/205
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US 08458491 Powell et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Carl Marshall Eliot Powell (Gaithersburg, Maryland);  John-Francis Mergen (Baltimore, Maryland);  John G. Griffith, III (Mont Vernon, New Hampshire)
ASSIGNEE(S) Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S) Carl Marshall Eliot Powell (Gaithersburg, Maryland);  John-Francis Mergen (Baltimore, Maryland);  John G. Griffith, III (Mont Vernon, New Hampshire)
ABSTRACT A cryptographically scrubbable disk performs erasure of a cryptographic key covering a body of data to render the body of data unintelligible. A scrub controller interfaced between a computing appliance and a storage volume generates a scrub key and encrypts each block of data written to the storage volume using the scrub key. Data read commands decrypt using the same key. The scrub controller is an electronically separate conduit having independent memory and power, thus the scrub key remains within the scrub controller and unexposed, and is thus inaccessible via the processor of the computing appliance. The scrub key remains in the scrub controller such that the scrub key never leaves the scrub controller and is also inaccessible to retrieval since the scrub controller does not share memory or access with the computer and is thus electronically separate from the supported computing appliance.
FILED Wednesday, June 23, 2010
APPL NO 12/821275
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Support
713/190
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US 08458525 Pargellis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Andrew Pargellis (Pomona, California);  Brian M. Sutin (Claremont, California)
ASSIGNEE(S) Hamilton Sundstrand Space Systems International, Inc. (Windsor Locks, Connecticut)
INVENTOR(S) Andrew Pargellis (Pomona, California);  Brian M. Sutin (Claremont, California)
ABSTRACT A diagnostic device identifies failed sub-modules within a larger system based on error codes received from the system. The device stores a likelihood matrix that correlates each sub-module with each possible error code and maintains a likelihood value corresponding to the probability of a failed sub-module generating a corresponding error code and stores a prior probability of failure associated with each sub-module based on prior observational data. In response to received error codes, the device calculates a posterior probability of failure for each of the plurality of sub-modules based on a product of the likelihood values corresponding to the received error codes and the prior probability of failure associated with each sub-module. Based on the calculated posterior probability, the device identifies the sub-module with the highest posterior probability of failure as the failed sub-module.
FILED Friday, March 19, 2010
APPL NO 12/727437
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/37
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US 08458649 Bouillet et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New Jersey);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New Jersey);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ABSTRACT A method, including: receiving a software requirement; and constructing a workflow template that can satisfy the software requirement, wherein the workflow template comprises a plurality of processing stages, wherein each processing stage includes at least one component class and each component class includes at least one component, and wherein an output of each processing stage is described by a processing goal pattern that is described by a set of tags and facets.
FILED Wednesday, October 15, 2008
APPL NO 12/252156
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/106
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458650 Andrade et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Henrique Andrade (Croton-on-Hudson, New York);  Bugra Gedik (White Plains, New York);  Gabriela Jacques da Silva (Champaign, Illinois);  Kun-Lung Wu (Yorktown Heights, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Henrique Andrade (Croton-on-Hudson, New York);  Bugra Gedik (White Plains, New York);  Gabriela Jacques da Silva (Champaign, Illinois);  Kun-Lung Wu (Yorktown Heights, New York)
ABSTRACT In one embodiment, the invention comprises partial fault tolerant stream processing applications. One embodiment of a method for implementing partial fault tolerance in a stream processing application comprising a plurality of stream operators includes: defining a quality score function that expresses how well the application is performing quantitatively, injecting a fault into at least one of the plurality of operators, assessing an impact of the fault on the quality score function, and selecting at least one partial fault-tolerant technique for implementation in the application based on the quantitative metric-driven assessment.
FILED Monday, March 29, 2010
APPL NO 12/748633
ART UNIT 2198 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/106
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458679 Archambault et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Roch G. Archambault (North York, Canada);  Shimin Cui (Toronto, Canada);  Yaoqing Gao (North York, Canada)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Roch G. Archambault (North York, Canada);  Shimin Cui (Toronto, Canada);  Yaoqing Gao (North York, Canada)
ABSTRACT May-constant propagation is a technique used to propagate a constant through the call graph and control flow graph by ignoring possible kills and re-definitions with low probability. Variables associated with constants in program code are determined. Execution flow probabilities are executed for code segments of the program code that comprise the variables. The execution flow probabilities are calculated based on flow data for the program code. At least a first of the code segments is determined to have a high execution flow probability. The first of the constants associated with the first variable are propagated through the flow data to generate modified flow data.
FILED Wednesday, September 22, 2010
APPL NO 12/888230
ART UNIT 2197 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/146
VIEW PATENT @ USPTO:  Full Text   PDF 
US H2275 Burgin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Timothy P. Burgin (Mechanicsville, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Timothy P. Burgin (Mechanicsville, Virginia)
ABSTRACT A method of forming a film of carbon nanotubes on a substrate includes deposition a solution of electrically charged carbon nanotubes on the surface of a substrate, adsorption of the electrically charged carbon nanotubes onto a surface the substrate of opposite electrical charge through dip coating, using a material with a surface electrical charge opposite to that of the electrically charged carbon nanotubes, and formation of a film of carbon nanotubes on the substrate, wherein the film comprises a plurality of electrically charged nanotubes extending in varying orientations but parallel to a facing surface of the substrate.
FILED Monday, September 12, 2011
APPL NO 13/199959
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Coating processes
427/458
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US H2276 Burgin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Timothy P. Burgin (King George, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Timothy P. Burgin (King George, Virginia)
ABSTRACT A superabsorbent polymeric material for absorption of organic liquids which includes at least one cross-linked branched amide polymer for absorbing and retaining quantities of organic liquids equivalent to several times its dry weight.
FILED Monday, January 09, 2012
APPL NO 13/385467
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Synthetic resins or natural rubbers
526/303.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 08454512 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Lihong Wang (Creve Coeur, Missouri);  Konstantin Maslov (Affton, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Lihong Wang (Creve Coeur, Missouri);  Konstantin Maslov (Affton, Missouri)
ABSTRACT A confocal photoacoustic microscopy system includes a laser configured to emit a light pulse, a focusing assembly configured to receive the light pulse and to focus the light pulse into an area inside an object, an ultrasonic transducer configured to receive acoustic waves emitted by the object in response to the light pulse, and an electronic system configured to process the acoustic waves and to generate an image of the area inside the object. The focusing assembly is further configured to focus the light pulse on the object in such a way that a focal point of the focusing assembly coincides with a focal point of the at least one ultrasonic transducer.
FILED Friday, October 24, 2008
APPL NO 12/739589
ART UNIT 3768 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Surgery
6/437
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US 08454652 Cohen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Adam L. Cohen (Valley Village, California);  Christopher R. Folk (Los Angeles, California)
ASSIGNEE(S)
INVENTOR(S) Adam L. Cohen (Valley Village, California);  Christopher R. Folk (Los Angeles, California)
ABSTRACT Embodiments of invention are directed to tissue approximation instruments that may be delivered to the body of a patient during minimally invasive or other surgical procedures. In one group of embodiments, the instruments have an elongated configuration with two sets of expandable wings that each have spreadable wings that can be made to expand when located on opposite sides of a distal tissue region and a proximal tissue region and can then be made to move toward one another to bring the two tissue regions into a more proximate position. The instrument is delivered through a needle or catheter and is controlled by relative movement of a push tube and control wire wherein the control wire can be released from the instrument via rotation in a first direction and can cause release of the approximation device from tissue that it is holding by rotation in the opposite direction.
FILED Thursday, December 31, 2009
APPL NO 12/651388
ART UNIT 3773 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Surgery
66/218
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US 08454813 Voldman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Joel Voldman (Somerville, Massachusetts);  Brian Michael Taff (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Joel Voldman (Somerville, Massachusetts);  Brian Michael Taff (Cambridge, Massachusetts)
ABSTRACT The present invention provides a device and methods of use thereof in microscale cell sorting. This invention provides sorting cytometers, which trap individual cells within vessels following exposure to dielectrophoresis, allow for the assaying of trapped cells, such that a population is identified whose isolation is desired, and their isolation.
FILED Thursday, April 24, 2008
APPL NO 12/081995
ART UNIT 1759 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Chemistry: Electrical and wave energy
24/643
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US 08454906 Mathies et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Richard A. Mathies (San Francisco, California);  Palani Kumaresan (Los Angeles, California);  Chaoyang Yang (Xiamen, China PRC);  Robert G. Blazej (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard A. Mathies (San Francisco, California);  Palani Kumaresan (Los Angeles, California);  Chaoyang Yang (Xiamen, China PRC);  Robert G. Blazej (San Francisco, California)
ABSTRACT Provided are microfluidic designs and methods for rapid generation of monodisperse nanoliter volume droplets of reagent/target (e.g., molecule or cell) mix in emulsion oil. The designs and methods enable high-throughput encapsulation of a single target (e.g., DNA/RNA molecules or cells) in controlled size droplets of reagent mix. According to various embodiments, a microfabricated, 3-valve pump is used to precisely meter the volume of reagent/target mix in each droplet and also to effectively route microparticles such as beads and cells into the device, which are encapsulated within droplets at the intersection of the reagent channel and an oil channel. The pulsatile flow profile of the microfabricated pumps provides active control over droplet generation, thereby enabling droplet formation with oils that are compatible with biological reactions but are otherwise difficult to form emulsions with.
FILED Thursday, July 24, 2008
APPL NO 12/670377
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/505
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454936 Brechbiel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Martin Wade Brechbiel (Annandale, Virginia);  Thomas Clifford (Rockville, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health And Human Services (Washington, District of Columbia)
INVENTOR(S) Martin Wade Brechbiel (Annandale, Virginia);  Thomas Clifford (Rockville, Maryland)
ABSTRACT Metal chelators of Formula I and Formula II are disclosed: or a pharmaceutically acceptable salt thereof. Also disclosed are metal chelator-targeting moiety complexes, metal chelator-targeting moiety-metal conjugates, kits, and methods of their preparation and use in diagnosis and/or treatment of diseases and conditions, including, inter alia, cancer and thrombosis.
FILED Thursday, April 01, 2010
APPL NO 12/752419
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454952 Rade et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Jeffrey James Rade (Baltimore, Maryland);  Navin Kumar Kapur (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Jeffrey James Rade (Baltimore, Maryland);  Navin Kumar Kapur (Baltimore, Maryland)
ABSTRACT Stretch-induced increased hemodynamic load adversely affects endothelial cell function and is an important contributor to thromboembolus formation in heart failure, valvular heart disease, atrial fibrillation, venous insufficiency, and pulmonary hypertension, and in thrombus occluded vein grafts. Local thrombus formation and thromboenbolic events can be reduced by inhibiting the TGF-beta signaling pathway or TGF-beta per se. Inhibitors can be administered to patients or veins (prior to interposition) at risk for thromboembolic events or local thrombus formation. Inhibitors can be applied to harvested veins to be used as arterial grafts.
FILED Tuesday, March 13, 2007
APPL NO 12/282769
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454958 Varner
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Judith A. Varner (Encinitas, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Judith A. Varner (Encinitas, California)
ABSTRACT The present invention provides methods for reducing or inhibiting angiogenesis in a tissue, by contacting α5β1 integrin in the tissue with an agent that interferes with specific binding of the α5β1 integrin to a ligand expressed in the tissue. The invention further provides methods of reducing or inhibiting angiogenesis in a tissue in an individual, by administering to the individual an agent that interferes with the specific binding of α5β1 integrin to a ligand expressed in the tissue; and methods of reducing the severity of a pathological condition associated with angiogenesis in an individual, by administering to the individual an agent that interferes with specific binding of α5β1 integrin to a ligand in a tissue associated with the pathological condition.
FILED Wednesday, December 07, 2011
APPL NO 13/314040
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454963 Tomlinson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Stephen Tomlinson (Mt. Pleasant, South Carolina);  Richard J. Quigg (Hinsdale, Illinois)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina);  University of Chicago (Chicago, Illinois)
INVENTOR(S) Stephen Tomlinson (Mt. Pleasant, South Carolina);  Richard J. Quigg (Hinsdale, Illinois)
ABSTRACT Systemic suppression of the complement system has been shown to be effective to treat inflammatory disease, yet at the potential cost of compromising host defense and immune homeostasis. Herein disclosed are methods for antigen-specific targeting of complement inhibitors that show that complement inhibitors targeted to the proximal tubular epithelium protect against tubulointerstitial injury and renal dysfunction in a rat model of nephrosis. It is shown that appropriate targeting of a systemically administered complement inhibitor to a site of disease markedy enhances efficacy and obviates the need to systemically inhibit complement. Additionally, it is shown by specifically inhibiting the terminal pathway of complement, that the membrane attack complex (MAC) plays a key role in proteinuria-induced tubulointerstitial injury, thus establishing the MAC as a valid target for pharmacological intervention in proteinuric disorders. The disclosed are compositions can be used in methods of treating pathogenic diseases and inflammatory conditions by modulating the complement system.
FILED Thursday, April 28, 2005
APPL NO 11/116939
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/178.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454965 Martin et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Roland Martin (Hamburg, Germany);  Henry McFarland (Gaithersburg, Maryland);  Bibiana Bielekova (Kensington, Maryland)
ASSIGNEE(S) The United States of America as represented by The Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Roland Martin (Hamburg, Germany);  Henry McFarland (Gaithersburg, Maryland);  Bibiana Bielekova (Kensington, Maryland)
ABSTRACT A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to the subject a therapeutically effective amount of an IL-21 receptor antagonist, wherein the subject has failed to respond treatment with beta interferon, thereby treating the subject.
FILED Friday, July 13, 2007
APPL NO 11/827876
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/184.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454972 Nabel et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Gary J. Nabel (Washington, District of Columbia);  Ling Xu (Potomac, Maryland);  Bimal Chakrabarti (San Diego, California);  Lan Wu (Germantown, Maryland);  Zhi-yong Yang (Potomac, Maryland);  Jason G. D. Gall (Germantown, Maryland);  C. Richter King (New York, New York);  Zengguang Wang (Silver Spring, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia);  GenVec, Inc. (Gaithersburg, Maryland)
INVENTOR(S) Gary J. Nabel (Washington, District of Columbia);  Yue Huang (Silver Spring, Maryland);  Ling Xu (Potomac, Maryland);  Bimal Chakrabarti (San Diego, California);  Lan Wu (Germantown, Maryland);  Zhi-yong Yang (Potomac, Maryland);  Jason G. D. Gall (Germantown, Maryland);  C. Richter King (New York, New York)
ABSTRACT The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.
FILED Thursday, January 20, 2011
APPL NO 13/010141
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/208.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454977 Hodges et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Robert S. Hodges (Denver, Colorado);  Randall T. Irvin (Sherwood Park, Canada);  Carmen Giltner (St. Albert, Canada);  Erin Van Schaik (Calgary, Canada)
ASSIGNEE(S) The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
INVENTOR(S) Robert S. Hodges (Denver, Colorado);  Randall T. Irvin (Sherwood Park, Canada);  Carmen Giltner (St. Albert, Canada);  Erin Van Schaik (Calgary, Canada)
ABSTRACT The present invention relates to a composition, device and method for preventing or inhibiting biofilm formation on biotic or abiotic surfaces. The composition comprises a peptide based on the C-terminal receptor binding domain of Pseudomonas aeruginosa type IV pilin, which binds to an abiotic surface (e.g., steel, plastic) with high affinity and prevents binding of a variety of P. aeruginosa strains to the surface. The inventive composition represents a non-toxic inhibitor for biofilm formation, particularly on an abiotic surface, which is responsible for a large number of problematic diseases and massive economic losses. The inventive method is useful as a safe and environmentally friendly means of modifying a surface of a variety of biomedical, nanotechnological, and biotechnological devices or articles.
FILED Friday, July 08, 2011
APPL NO 13/179058
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/260.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455009 Tseng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Scheffer Tseng (Pinecrest, Florida);  Hua He (Miami, Florida);  Wei Li (Songgang Town, China PRC)
ASSIGNEE(S) TissueTech, Inc. (Miami, Florida)
INVENTOR(S) Scheffer Tseng (Pinecrest, Florida);  Hua He (Miami, Florida);  Wei Li (Songgang Town, China PRC)
ABSTRACT Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases.
FILED Monday, April 23, 2012
APPL NO 13/453771
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/583
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455188 Taylor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Douglas D. Taylor (Louisville, Kentucky);  Cicek Gercel-Taylor (Louisville, Kentucky)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) Douglas D. Taylor (Louisville, Kentucky);  Cicek Gercel-Taylor (Louisville, Kentucky)
ABSTRACT The presently disclosed subject matter provides modified cell-derived exosomes substantially lacking one or more immunosuppressive polypeptides. The presently-disclosed subject matter further provides methods of producing the modified exosomes and methods of using the modified exosomes for treating cancers.
FILED Monday, January 28, 2008
APPL NO 12/524432
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455191 Harding et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Paul A. Harding (Oxford, Ohio);  Zhenqing Zhou (Oxford, Ohio)
ASSIGNEE(S) Miami University (Oxford, Ohio)
INVENTOR(S) Paul A. Harding (Oxford, Ohio);  Zhenqing Zhou (Oxford, Ohio)
ABSTRACT A method for converting animal cells into brown adipose tissue cells is provided that includes transforming the animal cells using an expression vector. The expression vector includes a nucleotide sequence encoding HB-EGF operatively linked to a promoter and a nucleotide sequence encoding ADAM 12 operatively linked to a promoter. Converting animal cells to brown adipose tissue cells can be used to treat obesity or to treat cancer by converting target cells to brown adipose tissue cells.
FILED Monday, August 30, 2010
APPL NO 12/871209
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455206 Lobel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Peter Lobel (Highland Park, New Jersey);  David Sleat (Scotch Plains, New Jersey)
ASSIGNEE(S) University of Medicine and Dentistry of New Jersey (Newark, New Jersey)
INVENTOR(S) Peter Lobel (Highland Park, New Jersey);  David Sleat (Scotch Plains, New Jersey)
ABSTRACT The gene associated and causative of classical late infantile neuronal ceroid lipofuscinosis (LINCL), CLN2, has been identified and characterized. The translation product of this gene is a novel protease and a deficiency in this activity results in LINCL. Identification of CLN2 will not only aid in the prevention of LINCL through genetic counseling but provides strategies and test systems for therapeutic intervention. In addition, further characterization of this previously unknown lysosomal enzyme may provide useful insights into other more common human neurodegenerative disorders. Finally, the utility of a general approach for determining the molecular bases for lysosomal disorders of unknown etiology has been demonstrated.
FILED Friday, December 23, 2011
APPL NO 13/336662
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455214 Jacobs, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) William R. Jacobs, Jr. (Pelham, New York);  Rainer Kalscheuer (Hilden, Germany);  Stephen Bornemann (Norwich, United Kingdom);  Karl Syson (Norwich, United Kingdom)
ASSIGNEE(S) Albert Einstein College of Medicine of Yeshiva University (Bronx, New York);  Plant Bioscience Limited (Norwich, United Kingdom)
INVENTOR(S) William R. Jacobs, Jr. (Pelham, New York);  Rainer Kalscheuer (Hilden, Germany);  Stephen Bornemann (Norwich, United Kingdom);  Karl Syson (Norwich, United Kingdom)
ABSTRACT The present invention provides methods for determining a putative antibacterial, the methods comprising determining whether the putative antibacterial inhibits GlgE or Rv3032. The present invention also provides the antibacterial, the pharmaceutical composition and the method of making the antibacterial as well as a method of treating a subject infected with a bacterial comprising administration of the antibacterial.
FILED Tuesday, October 26, 2010
APPL NO 12/925633
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/32
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455245 Frank
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Markus H. Frank (Cambridge, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Markus H. Frank (Cambridge, Massachusetts)
ABSTRACT The present invention is directed to purified preparations of dermal mesenchymal stem cells that are characterized by the cell surface expression of the ABCB5 P-glycoprotein. The cells may be used for any purpose that mesenchymal stem cells from other course are used. For instance they may be administered to treat an organ transplant recipient to improve allograft survival or as a treatment to patients with autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.
FILED Thursday, May 31, 2007
APPL NO 11/809790
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455252 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Jian-Ting Zhang (Carmel, Indiana);  Jing Qi (Carmel, Indiana);  Hui Peng (Beijin, China PRC);  Zizheng Dong (Carmel, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corp. (Indianapolis, Indiana)
INVENTOR(S) Jian-Ting Zhang (Carmel, Indiana);  Jing Qi (Carmel, Indiana);  Hui Peng (Beijin, China PRC);  Zizheng Dong (Carmel, Indiana)
ABSTRACT Disclosed herein are materials and methods for sensitizing multidrug resistant cancer cells that express ABCG2 and related proteins members of a family of ATP-binding transporter superfamily that mediate drug efflux found in some types of multidrug resistant cancer cells. A series of compounds, including (N-(4-chlorophenyl)-2-[(6-{[4,6-di(4-morpholinyl)-1,3,5-tri-azin-2-yl]amino}-1,3-benzothiazol-2-yl)sulfanyl]acetamide), specifically inhibits ABCG2 and can be used to boost the bio-avail-ability of one or more effective cancer killing drugs, making it possible to use certain widely used chemotherapeutic reagent to treat multidrug resistance cancers. Using these compounds in combination with chemotherapeutic drugs that are substrates for ABCG2 and related proteins may also find utility in treating cancer cells that are not currently identified as multi-drug resistant. Additionally, these compounds appear to accelerate the intercellular degradation of ABCG2 and related proteins. They are not toxic to animals at levels at which they effect the activity of ABCG2 expressed in multi-drug resistant cancer lines.
FILED Saturday, October 24, 2009
APPL NO 13/125530
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455258 Quake et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Stephen R. Quake (San Marino, California);  Marc A. Unger (South San Francisco, California);  Hou-Pu Chou (Sunnyvale, California);  Todd A. Thorsen (Pasadena, California);  Axel Scherer (Laguna Beach, California)
ASSIGNEE(S) California Insitute of Technology (Pasadena, California)
INVENTOR(S) Stephen R. Quake (San Marino, California);  Marc A. Unger (South San Francisco, California);  Hou-Pu Chou (Sunnyvale, California);  Todd A. Thorsen (Pasadena, California);  Axel Scherer (Laguna Beach, California)
ABSTRACT The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.
FILED Tuesday, February 15, 2011
APPL NO 13/027768
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/63
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455427 Maines
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Mahin D. Maines (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Mahin D. Maines (Rochester, New York)
ABSTRACT The present invention relates to a method of modulating insulin signaling in a cell. This method involves modifying the nuclear or cellular concentration of biliverdin reductase, or fragments or variants thereof, in a cell, whereby a change in nuclear or cellular concentration of biliverdin reductase, or fragments or variants thereof, modulates insulin signaling in the cell via biliverdin reductase interaction with one or both of insulin receptor kinase domain and insulin receptor substrate. Also disclosed are methods of treating a condition associated with insulin signaling and treating a patient for a condition associated with insulin-mediated glucose uptake.
FILED Tuesday, February 21, 2006
APPL NO 11/816557
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455431 Kisselev et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Alexei Kisselev (West Lebanon, New Hampshire);  Dmitry V. Filippov (Leiden, Netherlands);  Herman Overkleeft (Leiden, Netherlands)
ASSIGNEE(S) Trustees of Dartmout College (Hanover, New Hampshire);  Leiden University (Leiden, Netherlands)
INVENTOR(S) Alexei Kisselev (West Lebanon, New Hampshire);  Dmitry V. Filippov (Leiden, Netherlands);  Herman Overkleeft (Leiden, Netherlands)
ABSTRACT The present invention is an inhibitor of the trypsin-like β2/β2i sites of the proteasome. The inhibitor is characterized as being a peptide-based epoxyketone or vinyl sulfone that contains an arginine or 4-aminomethylene-L-phenylalanine at the C-terminus (i.e., at the P1 position). Methods for using the inhibitor to inhibit the activity of the β2/β2i site of a proteasome and treat a proteasome-mediated disease or condition are also described.
FILED Friday, February 17, 2012
APPL NO 13/399189
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/4.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455434 Cox
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) George N. Cox (Louisville, Colorado)
ASSIGNEE(S) Bolder Biotechnology, Inc. (Boulder, Colorado)
INVENTOR(S) George N. Cox (Louisville, Colorado)
ABSTRACT The growth hormone supergene family comprises greater than 20 structurally related cytokines and growth factors. A general method is provided for creating site-specific, biologically active conjugates of these proteins. The method involves adding cysteine residues to non-essential regions of the proteins or substituting cysteine residues for non-essential amino acids in the proteins using site-directed mutagenesis and then covalently coupling a cysteine-reactive polymer or other type of cysteine-reactive moiety to the proteins via the added cysteine residue. Disclosed herein are preferred sites for adding cysteine residues or introducing cysteine substitutions into the proteins, and the proteins and protein derivatives produced thereby. Also disclosed are therapeutic methods for using the cysteine variants of the invention.
FILED Wednesday, June 15, 2011
APPL NO 13/161333
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/7.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455437 Sitkovsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Michail V. Sitkovsky (Boston, Massachusetts);  Manfred Thiel (Eichenau, Germany)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Michail V. Sitkovsky (Boston, Massachusetts);  Manfred Thiel (Eichenau, Germany)
ABSTRACT Methods for modulating responsiveness to increased oxygen levels in an at-risk subject identifying an at-risk subject; and before exposing the identified at-risk subject to an increased amount of oxygen, administering to the at-risk subject an anti-inflammatory agent wherein the responsiveness of the at-risk subject to said increased amount of oxygen is modulated as compared to the responsiveness of the at-risk subject to said increased amount of oxygen in the absence of said anti-inflammatory.
FILED Wednesday, January 25, 2006
APPL NO 11/339208
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455443 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Wei Li (Altadena, California);  Mei Chen (Altadena, California);  David T. Woodley (Altadena, California);  Chieh-Fang Cheng (Alhambra, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Wei Li (Altadena, California);  Mei Chen (Altadena, California);  David T. Woodley (Altadena, California);  Chieh-Fang Cheng (Alhambra, California)
ABSTRACT A wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain. The composition includes a pharmaceutical medium to carry the polypeptide compound, such as an aqueous solution, suspension, dispersion, salve, ointment, gel, cream, lotion, spray or paste. Additionally, a method of applying a wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain in a concentration of from about 1 μg/ml to about 100 μg/ml for a time sufficient to heal the wound is disclosed.
FILED Wednesday, May 30, 2012
APPL NO 13/484162
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/16.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455454 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Fei Wang (Bethesda, Maryland);  Sheldon Miller (Bethesda, Maryland);  Congxiao Zhang (Rockville, Maryland);  Arvydas Maminishkis (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Fei Wang (Bethesda, Maryland);  Sheldon Miller (Bethesda, Maryland);  Congxiao Zhang (Rockville, Maryland);  Arvydas Maminishkis (Washington, District of Columbia)
ABSTRACT Embodiments of the invention provide methods of preventing or treating detrimental epithelial cell proliferation, loss of epithelial cell differentiation, age-related macular degeneration and/or proliferative vitreal retinopathy in an individual comprising administering to an individual in need thereof an effective amount of miR 204, an effective amount of miR 211, or an effective amount of a mixture of miR 204 and miR 211. A further embodiment of the invention provides a method of facilitating the transport of a substance across an epithelium in an individual comprising administrating to an individual an effective amount of anti-miR 204, an effective amount of anti-miR 211, or an effective amount of a mixture of anti-miR 204 and anti-miR 211. Additional embodiments of the invention include pharmaceutical compositions of miR 204 and/or miR 211 and pharmaceutical compositions of anti-miR 204 and/or anti-miR 211.
FILED Wednesday, August 26, 2009
APPL NO 13/060877
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455468 Hoffman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Stuart W. Hoffman (Atlanta, Georgia);  Arthur L. Kellermann (Atlanta, Georgia);  Donald G Stein (Atlanta, Georgia);  David W. Wright (Atlanta, Georgia);  Douglas W. Lowery-North (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Stuart W. Hoffman (Atlanta, Georgia);  Arthur L. Kellermann (Atlanta, Georgia);  Donald G Stein (Atlanta, Georgia);  David W. Wright (Atlanta, Georgia);  Douglas W. Lowery-North (Atlanta, Georgia)
ABSTRACT Methods of treating a subject with a traumatic central nervous system injury, more particularly, a traumatic brain injury, are provided. The methods comprise a therapy comprising a constant or a two-level dosing regime of progesterone. In one method, a subject in need thereof is administered at least one cycle of therapy, wherein the cycle of therapy comprises administering a therapeutically effective two-level intravenous dosing regime of progesterone. The two-level dosing regime comprises a first time period, wherein a higher hourly dose of progesterone is administered to the subject, followed by a second time period, wherein a lower hourly dose of progesterone is administered to the subject.
FILED Thursday, March 10, 2011
APPL NO 13/045180
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/170
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455490 DeGrado et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) William F. DeGrado (Moylan, Pennsylvania);  Gregory N. Tew (Amherst, Massachusetts);  Michael L. Klein (Ocean City, New Jersey);  Dahui Liu (Wynnewood, Pennsylvania);  Jing Yuan (Lansdale, Pennsylvania);  Sungwook Choi (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) William F. DeGrado (Moylan, Pennsylvania);  Gregory N. Tew (Amherst, Massachusetts);  Michael L. Klein (Ocean City, New Jersey);  Dahui Liu (Wynnewood, Pennsylvania);  Jing Yuan (Lansdale, Pennsylvania);  Sungwook Choi (Philadelphia, Pennsylvania)
ABSTRACT The present invention discloses methods of use of facially amphiphilic polymers and oligomers, including pharmaceutical uses of the polymers and oligomers as antimicrobial agents and antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polymers and oligomers and their compositions, including pharmaceutical compositions. The present invention further discloses the design and synthesis of facially amphiphilic polymers and oligomers.
FILED Thursday, July 26, 2012
APPL NO 13/559065
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/247
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455516 Gochin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Miriam Gochin (San Francisco, California);  Guangyan Zhou (American Canyon, California)
ASSIGNEE(S) Touro University (Vallejo, California)
INVENTOR(S) Miriam Gochin (San Francisco, California);  Guangyan Zhou (American Canyon, California)
ABSTRACT A new series of HIV-1 fusion inhibitors and methods of use are disclosed. The compounds are based on a substituted indole, benzimidazole, indoline or isoindoline fragment. The compounds find use in inhibiting or preventing HIV fusion from occurring, thus inhibiting or preventing entry of viral RNA into host cells. The compounds may be useful towards other biological targets involving protein-protein interactions.
FILED Friday, January 14, 2011
APPL NO 13/006716
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/314
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455523 Hussain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) M. Mahmood Hussain (Woodbury, New York);  Jahangir Igbal (Jersey City, New Jersey);  Joby Josekutty (Brooklyn, New York)
ASSIGNEE(S) The Research Foundation of State University of New York (Albany, New York)
INVENTOR(S) M. Mahmood Hussain (Woodbury, New York);  Jahangir Igbal (Jersey City, New Jersey);  Joby Josekutty (Brooklyn, New York)
ABSTRACT The present invention is directed to a composition and method for the treatment of hyperlipidemias by targeting Microsomal triglyceride transfer protein (MTP). In particular, the present invention is directed to a combination of at least one MTP inhibitor and at least one lipid-lowering agent, both in an amount effective to treat hyperlipidemias.
FILED Friday, January 07, 2011
APPL NO 12/930532
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/342
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455553 David
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Michael David (San Diego, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael David (San Diego, California)
ABSTRACT The invention provides compositions and methods for reducing one or more symptoms of an autoimmune disease, inflammatory disease, and/or transplant rejection, by the administration to a subject in need thereof a pharmaceutically effective amount of a purified compound of any one of Formulae A-E. The invention's methods are useful for the prevention, amelioration, and treatment of autoimmune disease, inflammatory disease, and/or transplant rejection.
FILED Thursday, November 10, 2011
APPL NO 13/293876
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/720
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455565 Abuelyaman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Ahmed S. Abuelyaman (Woodbury, Minnesota);  Joel D. Oxman (Minneapolis, Minnesota);  Yizhong Wang (Woodbury, Minnesota);  Christopher N. Bowman (Boulder, Colorado);  Hee Young Park (Asan-si, South Korea);  Christopher J. Kloxin (Newark, Delaware)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota);  The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Ahmed S. Abuelyaman (Woodbury, Minnesota);  Joel D. Oxman (Minneapolis, Minnesota);  Yizhong Wang (Woodbury, Minnesota);  Christopher N. Bowman (Boulder, Colorado);  Hee Young Park (Asan-si, South Korea);  Christopher J. Kloxin (Newark, Delaware)
ABSTRACT Dental compositions and disulfide monomers are described. The disulfide monomer comprise a disulfide backbone group wherein each of the sulfur atoms are bonded to an ethylenically unsaturated group via a divalent linking group and the linking group comprises at least one heteroatom; and at least one other monomer ethylenically unsaturated monomer.
FILED Wednesday, May 18, 2011
APPL NO 13/110900
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
523/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455616 Ishizaka et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
Center for Global Health (CGH)
APPLICANT(S) Yukihito Ishizaka (Tokyo, Japan);  Masakatsu Hasegawa (Nagoya, Japan);  Satoshi Nohara (Gifu, Japan)
ASSIGNEE(S) National Center for Global Health and Medicine (Tokyo, Japan)
INVENTOR(S) Yukihito Ishizaka (Tokyo, Japan);  Masakatsu Hasegawa (Nagoya, Japan);  Satoshi Nohara (Gifu, Japan)
ABSTRACT The present invention provides a peptide comprising amino acid sequences R I, F I and R I G C and containing 25 or fewer amino acid residues, and capable of transporting a functional molecule into a cell, and also into a nucleus, more efficiently than a previous PTD.
FILED Thursday, March 06, 2008
APPL NO 12/450010
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/328
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455621 Krug et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Robert M. Krug (Austin, Texas);  Karen Y. Twu (San Mateo, California);  Rei-Lin Kuo (Austin, Texas);  Gaetano Montelione (Highland Park, New Jersey);  Edward Arnold (Belle Mead, New Jersey);  Kalyan Das (Edison, New Jersey);  LiChung Ma (Plainsboro, New Jersey);  Rong Xiao (Princeton, New Jersey)
ASSIGNEE(S) Rutgers, The State University of New Jersery (New Brunswick, New Jersey);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Robert M. Krug (Austin, Texas);  Karen Y. Twu (San Mateo, California);  Rei-Lin Kuo (Austin, Texas);  Gaetano Montelione (Highland Park, New Jersey);  Edward Arnold (Belle Mead, New Jersey);  Kalyan Das (Edison, New Jersey);  LiChung Ma (Plainsboro, New Jersey);  Rong Xiao (Princeton, New Jersey)
ABSTRACT The present invention includes compositions and methods related to the structure and function of the cellular polyadenylation and specificity factor 30 (CPSF30) binding site on the surface of the influenza A non-structural protein 1 (NS1). Specifically, critical biochemical reagents, conditions for crystallization and NMR analysis, assays, and general processes are described for (i) discovering, designing, and optimizing small molecule inhibitors of influenza A (avian flu) viruses and (ii) creating attenuated influenza virus strains suitable for avian and human flu vaccine development.
FILED Wednesday, February 17, 2010
APPL NO 12/706804
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455652 Hammock et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Bruce D. Hammock (Davis, California);  In-Hae Kim (Kwangji, South Korea);  Christophe Morisseau (West Sacramento, California);  Takaho Watanabe (Kanagawa, Japan);  John W. Newman (Woodland, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Bruce D. Hammock (Davis, California);  In-Hae Kim (Kwangji, South Korea);  Christophe Morisseau (West Sacramento, California);  Takaho Watanabe (Kanagawa, Japan);  John W. Newman (Woodland, California)
ABSTRACT Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
FILED Monday, March 02, 2009
APPL NO 12/396391
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Organic compounds
546/285
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455818 Coon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Joshua J. Coon (Middleton, Wisconsin);  Douglas H. Phanstiel (Los Altos, California);  Craig D. Wenger (Santa Clara, California)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Joshua J. Coon (Middleton, Wisconsin);  Douglas H. Phanstiel (Los Altos, California);  Craig D. Wenger (Santa Clara, California)
ABSTRACT Described herein are methods and systems which enable a unique platform for analyte quantitation. The methods and systems relate to determining the amount of interference in a precursor ion isolation window resulting from an impurity. Once the level of impurity is determined, several methods can be employed to reduce the amount of interference in a subsequent MS/MS spectrum. The methods and systems described herein enable increased quantitation accuracy while maintaining high levels of throughput.
FILED Thursday, April 14, 2011
APPL NO 13/086638
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/290
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456150 Shih et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Wan Y. Shih (Bryn Mawr, Pennsylvania);  Wei-Heng Shih (Bryn Mawr, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Wan Y. Shih (Bryn Mawr, Pennsylvania);  Wei-Heng Shih (Bryn Mawr, Pennsylvania)
ABSTRACT The invention is directed to a novel phase-shift detector capable of interfacing with an array of sensors. The detector is light-weight, portable and capable of fitting within the palm of a hand. The detector may be used in conjunction with a variety of diagnostic, biosensor and chemical sensor applications.
FILED Wednesday, January 30, 2008
APPL NO 12/524876
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/76.770
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456725 Toomre et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Derek Kalev Toomre (New Haven, Connecticut);  Vladimir Ivanovich Polejaev (Middletown, Connecticut);  Robert Dixon Roorda (Oxford, United Kingdom)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Derek Kalev Toomre (New Haven, Connecticut);  Vladimir Ivanovich Polejaev (Middletown, Connecticut);  Robert Dixon Roorda (Oxford, United Kingdom)
ABSTRACT There is provided a method that includes projecting a collimated light beam from an optical system to a plane during a first mode of operation of the optical system, and projecting a convergent light beam from the optical system to the plane during a second mode of operation of the optical system. The method further includes, (a) during the first mode of operation, controlling a trajectory of a first light bundle in a first light path in the optical system, to steer the collimated light beam through the plane at a designated incidence angle, and (b) during the second mode of operation, controlling a trajectory of a second light bundle in a second light path of the optical system, to steer the convergent light beam to a target position in the plane. There is also provided an apparatus and a system that employs the method.
FILED Wednesday, March 25, 2009
APPL NO 12/866314
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/201.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456738 Ilev et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Ilko K. Ilev (Rockville, Maryland);  Ronald W. Waynant (Clarksville, Maryland);  Israel Gannot (Kensington, Maryland);  Amir H. Gandjbakhche (Potomac, Maryland)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Ilko K. Ilev (Rockville, Maryland);  Ronald W. Waynant (Clarksville, Maryland);  Israel Gannot (Kensington, Maryland);  Amir H. Gandjbakhche (Potomac, Maryland)
ABSTRACT An ultrahigh-resolution fiber-optic confocal microscope has an illumination system; three single-mode optical fibers, each optically coupled to a fiber coupler; a sample support stage arranged to receive illumination radiation from an end of one of the single-mode optical fibers; a detector arranged to receive output radiation from one of the single-mode optical fibers; and a lock-in amplifier electrically connected to the detector and the illumination system. The illumination system is adapted to provide illumination radiation that has a time-varying strength that is correlated with the detector by the lock-in amplifier.
FILED Friday, April 14, 2006
APPL NO 11/918313
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/368
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457712 Unal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Orhan Unal (Fitchburg, Wisconsin);  Krishna N. Kurpad (Middleton, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Orhan Unal (Fitchburg, Wisconsin);  Krishna N. Kurpad (Middleton, Wisconsin)
ABSTRACT A multi-mode medical device system and method of performing an interventional procedure. The multi-mode medical device system can be capable of MR internal imaging and of being tracked using an MRI system. The multi-mode medical device system can include a medical device, and an electrical circuit coupled to the medical device and electrically coupled to the MRI system. The electrical circuit can include a tracking device configured to transmit a signal to the MRI system indicative of the position of the tracking device relative to a roadmap image, and an imaging device electrically coupled to the tracking device and configured to internally image anatomical structures from the point of view of the medical device. The imaging device can be further configured to be visualized using MR imaging. Tracking the tracking device and internally imaging with the imaging device can be performed in a single pass of the multi-mode medical device system.
FILED Friday, December 30, 2005
APPL NO 11/322451
ART UNIT 3777 — Optics
CURRENT CPC
Surgery
6/411
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457733 Linninger
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Andreas Linninger (Oak Park, Illinois)
ASSIGNEE(S)
INVENTOR(S) Andreas Linninger (Oak Park, Illinois)
ABSTRACT Systems and methods for monitoring cerebral spinal fluid (CSF) based on electrical impedance measurements are disclosed. The systems can include an excitation source of alternating current (202), at least two sensor electrodes (212,214) adapted for disposition within CSF in a ventricle of a subject's brain, and an impedance measuring device (204) electrically connected to the sensor electrodes (212,214) to measure impedance of CSF. Methods for controlling hydrocephalus are also disclosed and such methods can include the steps of disposing an impedance sensor (902) within CSF in a ventricle of a subject's brain, measuring impedance of the CSF with the sensor (902), and withdrawing CSF when the impedance measurement is less than a threshold value.
FILED Monday, July 02, 2007
APPL NO 12/305484
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/547
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457748 Lange
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Gudrun Lange (Lake Hopatcong, New Jersey)
ASSIGNEE(S) University of Medicine and Dentistry of New Jersey (Somerset, New Jersey)
INVENTOR(S) Gudrun Lange (Lake Hopatcong, New Jersey)
ABSTRACT This invention relates to the use of vagus nerve stimulation for the treatment of fibromyalgia which comprises applying a therapeutic stimulation signal from a stimulus generator, when activated, to at least some of plural electrodes implanted in stimulating relation of the patient's vagus nerve and activating the stimulus generator to generate the therapeutic stimulation signal to alleviate the pain under treatment.
FILED Friday, February 06, 2009
APPL NO 12/322741
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/46
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457752 Greenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Robert J. Greenberg (Los Angeles, California);  Matthew J. McMahon (Los Angeles, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert J. Greenberg (Los Angeles, California);  Matthew J. McMahon (Los Angeles, California)
ABSTRACT The present invention is a method of improving the contrast of electrical neural stimulation and expanding the dynamic range for brightness, and specifically a method of improving the contrast of an image supplied to the retina, or visual cortex, through a visual prosthesis. The background brightness for a blind subject is often not perfectly black, but a dark gray or brown. When stimulating visual neurons in the retina, low current stimulation tends to create a dark percept, the perception of a phosphene darker than the background brightness level perceived in the un-stimulated state. The human retina contains neurons that signal light increments (“on” cells) and neurons that signal light decrements (“off” cells). In a healthy retina, the on cells tend to fire in response to an increase in light above the background level, while the off cells tend to fire in response to a decrease in light below the background level.
FILED Friday, September 15, 2006
APPL NO 11/521681
ART UNIT 3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457753 Greenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Robert J. Greenberg (Los Angeles, California);  Matthew J. McMahon (Los Angeles, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert J. Greenberg (Los Angeles, California);  Matthew J. McMahon (Los Angeles, California)
ABSTRACT The present invention is a method of improving the contrast of electrical neural stimulation and expanding the dynamic range for brightness, and specifically a method of improving the contrast of an image supplied to the retina, or visual cortex, through a visual prosthesis. The background brightness for a blind subject is often not perfectly black, but a dark gray or brown. When stimulating visual neurons in the retina, low current stimulation tends to create a dark percept, the perception of a phosphene darker than the background brightness level perceived in the un-stimulated state. The human retina contains neurons that signal light increments (“on” cells) and neurons that signal light decrements (“off” cells). In a healthy retina, the on cells tend to fire in response to an increase in light above the background level, while the off cells tend to fire in response to a decrease in light below the background level.
FILED Thursday, October 25, 2007
APPL NO 11/923820
ART UNIT 3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457754 Horsager et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Alan Matthew Horsager (Los Angeles, California);  Scott H. Greenwald (Seattle, Washington);  Mark S. Humayun (Glendale, California);  Matthew J. McMahon (Los Angeles, California);  Ione Fine (Seattle, Washington);  Robert J. Greenberg (Los Angeles, California);  Geoffrey M. Boynton (Seattle, Washington)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Alan Matthew Horsager (Los Angeles, California);  Scott H. Greenwald (Seattle, Washington);  Mark S. Humayun (Glendale, California);  Matthew J. McMahon (Los Angeles, California);  Ione Fine (Seattle, Washington);  Robert J. Greenberg (Los Angeles, California);  Geoffrey M. Boynton (Seattle, Washington)
ABSTRACT An apparatus and method for retinal stimulation are shown. The method comprises varied parameters, including frequency, pulse width, and pattern of pulse trains to determine a stimulation pattern and neural perception threshold, and creating a model based on the neural perception thresholds to optimize patterns of neural stimulation.
FILED Thursday, December 06, 2007
APPL NO 11/952051
ART UNIT 3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457900 Pevzner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Pavel A. Pevzner (La Jolla, California);  Nuno F. C. Bandeira (La Jolla, California);  Dekel Tsur (Be'er Sheva, Israel)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Pavel A. Pevzner (La Jolla, California);  Nuno F. C. Bandeira (La Jolla, California);  Dekel Tsur (Be'er Sheva, Israel)
ABSTRACT Protein samples are processed to create a mixture of modified and unmodified or overlapping peptides which are analyzed using mass spectrometry. Correlations between the MS/MS spectra of peptide pairs allow the noise in individual MS/MS spectra to be greatly reduced. A small number of peptide reconstructions can be generated that are likely to contain the correct one. This allows for the de novo reconstruction of protein sequences and peptide and modification identification through a database search using extremely fast pattern matching, rather than time-consuming matching of spectra against databases.
FILED Thursday, March 22, 2007
APPL NO 12/279836
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Electric Digital Data Processing
G06F 19/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE44266 Mayfield
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Stephen P. Mayfield (Cardiff, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Stephen P. Mayfield (Cardiff, California)
ABSTRACT The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.
FILED Friday, January 16, 1998
APPL NO 11/197730
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 08453327 Allen
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) David B. Allen (Oviedo, Florida)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) David B. Allen (Oviedo, Florida)
ABSTRACT Fabricating a turbine component (50) by casting a core structure (30), forming an array of pits (24) in an outer surface (32) of the core structure, depositing a transient liquid phase (TLP) material (40) on the outer surface of the core structure, the TLP containing a melting-point depressant, depositing a skin (42) on the outer surface of the core structure over the TLP material, and heating the assembly, thus forming both a diffusion bond and a mechanical interlock between the skin and the core structure. The heating diffuses the melting-point depressant away from the interface. Subsurface cooling channels (35) may be formed by forming grooves (34) in the outer surface of the core structure, filling the grooves with a fugitive filler (36), depositing and bonding the skin (42), then removing the fugitive material.
FILED Friday, February 05, 2010
APPL NO 12/701025
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/889.721
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453498 Warren et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Oden L. Warren (New Brighton, Minnesota);  Syed Amanula Syed Asif (Bloomington, Minnesota);  Edward Cyrankowski (Woodbury, Minnesota);  Kalin Kounev (Shoreview, Minnesota)
ASSIGNEE(S) Hysitron, Inc. (Minneapolis, Minnesota)
INVENTOR(S) Oden L. Warren (New Brighton, Minnesota);  Syed Amanula Syed Asif (Bloomington, Minnesota);  Edward Cyrankowski (Woodbury, Minnesota);  Kalin Kounev (Shoreview, Minnesota)
ABSTRACT An actuatable capacitive transducer including a transducer body, a first capacitor including a displaceable electrode and electrically configured as an electrostatic actuator, and a second capacitor including a displaceable electrode and electrically configured as a capacitive displacement sensor, wherein the second capacitor comprises a multi-plate capacitor. The actuatable capacitive transducer further includes a coupling shaft configured to mechanically couple the displaceable electrode of the first capacitor to the displaceable electrode of the second capacitor to form a displaceable electrode unit which is displaceable relative to the transducer body, and an electrically-conductive indenter mechanically coupled to the coupling shaft so as to be displaceable in unison with the displaceable electrode unit.
FILED Tuesday, September 21, 2010
APPL NO 12/886745
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/105
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453515 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Jy-An Wang (Oak Ridge, Tennessee);  Zhili Feng (Knoxville, Tennessee);  Lawrence M. Anovitz (Oak Ridge, Tennessee);  Kenneth C. Liu (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BaHelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Jy-An Wang (Oak Ridge, Tennessee);  Zhili Feng (Knoxville, Tennessee);  Lawrence M. Anovitz (Oak Ridge, Tennessee);  Kenneth C. Liu (Oak Ridge, Tennessee)
ABSTRACT The invention provides fatigue testing of a material specimen while the specimen is disposed in a high pressure fluid environment. A specimen is placed between receivers in an end cap of a vessel and a piston that is moveable within the vessel. Pressurized fluid is provided to compression and tension chambers defined between the piston and the vessel. When the pressure in the compression chamber is greater than the pressure in the tension chamber, the specimen is subjected to a compression force. When the pressure in the tension chamber is greater than the pressure in the compression chamber, the specimen is subjected to a tension force. While the specimen is subjected to either force, it is also surrounded by the pressurized fluid in the tension chamber. In some examples, the specimen is surrounded by hydrogen.
FILED Friday, September 03, 2010
APPL NO 12/875169
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/807
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08453619 Marriott
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Craig D. Marriott (Clawson, Michigan)
ASSIGNEE(S) GM Global Technology Operations LLC (, None)
INVENTOR(S) Craig D. Marriott (Clawson, Michigan)
ABSTRACT A hydraulic valve actuation assembly may include a housing, a piston, a supply control valve, a closing control valve, and an opening control valve. The housing may define a first fluid chamber, a second fluid chamber, and a third fluid chamber. The piston may be axially secured to an engine valve and located within the first, second and third fluid chambers. The supply control valve may control a hydraulic fluid supply to the piston. The closing control valve may be located between the supply control valve and the second fluid chamber and may control fluid flow from the second fluid chamber to the supply control valve. The opening control valve may be located between the supply control valve and the second fluid chamber and may control fluid flow from the supply control valve to the second fluid chamber.
FILED Tuesday, January 04, 2011
APPL NO 12/984233
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Internal-combustion engines
123/321
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08454309 Bevington et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Christopher M. Bevington (Waitsfield, Vermont);  Garrett L. Bywaters (Waitsfield, Vermont);  Clint C. Coleman (Warren, Vermont);  Daniel P. Costin (Montpelier, Vermont);  William L. Danforth (Rochester, Vermont);  Jonathan A. Lynch (St. Johnsbury, Vermont);  Robert H. Rolland (Waitsfield, Vermont)
ASSIGNEE(S) Northern Power Systems Utility Scale, Inc. (Barre, Vermont)
INVENTOR(S) Christopher M. Bevington (Waitsfield, Vermont);  Garrett L. Bywaters (Waitsfield, Vermont);  Clint C. Coleman (Warren, Vermont);  Daniel P. Costin (Montpelier, Vermont);  William L. Danforth (Rochester, Vermont);  Jonathan A. Lynch (St. Johnsbury, Vermont);  Robert H. Rolland (Waitsfield, Vermont)
ABSTRACT A wind turbine comprising an electrical generator that includes a rotor assembly. A wind rotor that includes a wind rotor hub is directly coupled to the rotor assembly via a simplified connection. The wind rotor and generator rotor assembly are rotatably mounted on a central spindle via a bearing assembly. The wind rotor hub includes an opening having a diameter larger than the outside diameter of the central spindle adjacent the bearing assembly so as to allow access to the bearing assembly from a cavity inside the wind rotor hub. The spindle is attached to a turret supported by a tower. Each of the spindle, turret and tower has an interior cavity that permits personnel to traverse therethrough to the cavity of the wind rotor hub. The wind turbine further includes a frictional braking system for slowing, stopping or keeping stopped the rotation of the wind rotor and rotor assembly.
FILED Tuesday, February 22, 2011
APPL NO 13/032182
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/229
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455048 Fan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Hongyou Fan (Albuquerque, New Mexico);  Huimeng Wu (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Hongyou Fan (Albuquerque, New Mexico);  Huimeng Wu (Albuquerque, New Mexico)
ABSTRACT A method of making a nanostructure by preparing a face centered cubic-ordered metal nanoparticle film from metal nanoparticles, such as gold and silver nanoparticles, exerting a hydrostatic pressure upon the film at pressures of several gigapascals, followed by applying a non-hydrostatic stress perpendicularly at a pressure greater than approximately 10 GPA to form an array of nanowires with individual nanowires having a relatively uniform length, average diameter and density.
FILED Monday, September 13, 2010
APPL NO 12/880886
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455231 Laible et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Philip D. Laible (Villa Park, Illinois);  Deborah K. Hanson (Villa Park, Illinois)
ASSIGNEE(S) Uchicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Philip D. Laible (Villa Park, Illinois);  Deborah K. Hanson (Villa Park, Illinois)
ABSTRACT The invention provides an in vitro method for producing proteins, membrane proteins, membrane-associated proteins, and soluble proteins that interact with membrane-associated proteins for assembly into an oligomeric complex or that require association with a membrane for proper folding. The method comprises, supplying intracytoplasmic membranes from organisms; modifying protein composition of intracytoplasmic membranes from organism by modifying DNA to delete genes encoding functions of the organism not associated with the formation of the intracytoplasmic membranes; generating appropriate DNA or RNA templates that encode the target protein; and mixing the intracytoplasmic membranes with the template and a transcription/translation-competent cellular extract to cause simultaneous production of the membrane proteins and encapsulation of the membrane proteins within the intracytoplasmic membranes.
FILED Monday, February 08, 2010
APPL NO 12/702167
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/193
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455333 Spurgeon et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Joshua M. Spurgeon (Pasadena, California);  Katherine E. Plass (Lancaster, Pennsylvania);  Nathan S. Lewis (La Canada, California);  Harry A. Atwater (S. Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Joshua M. Spurgeon (Pasadena, California);  Katherine E. Plass (Lancaster, Pennsylvania);  Nathan S. Lewis (La Canada, California);  Harry A. Atwater (S. Pasadena, California)
ABSTRACT Reusing a Si wafer for the formation of wire arrays by transferring the wire arrays to a polymer matrix, reusing a patterned oxide for several array growths, and finally polishing and reoxidizing the wafer surface and reapplying the patterned oxide.
FILED Monday, July 16, 2012
APPL NO 13/550395
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/478
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455382 Carolan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Michael Francis Carolan (Allentown, Pennsylvania);  Charles Leonard Kibby (Benicia, California)
ASSIGNEE(S) Air Products and Chemicals, Inc. (Allentown, Pennsylvania)
INVENTOR(S) Michael Francis Carolan (Allentown, Pennsylvania);  Charles Leonard Kibby (Benicia, California)
ABSTRACT Process for fabricating a catalyzed ion transport membrane (ITM). In one embodiment, an uncatalyzed ITM is (a) contacted with a non-reducing gaseous stream while heating to a temperature and for a time period sufficient to provide an ITM possessing anion mobility; (b) contacted with a reducing gaseous stream for a time period sufficient to provide an ITM having anion mobility and essentially constant oxygen stoichiometry; (c) cooled while contacting the ITM with the reducing gaseous stream to provide an ITM having essentially constant oxygen stoichiometry and no anion mobility; and (d) treated by applying catalyst to at least one of (1) a porous mixed conducting multicomponent metallic oxide (MCMO) layer contiguous with a first side of a dense layer of MCMO and (2) a second side of the dense MCMO layer. In another embodiment, these steps are carried out in the alternative order of (a), (d), (b), and (c).
FILED Tuesday, May 25, 2010
APPL NO 12/786987
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455683 Burk et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Mark J. Burk (San Diego, California);  Priti Pharkya (San Diego, California);  Stephen J. Van Dien (Encinitas, California);  Anthony P. Burgard (Bellenfonte, Pennsylvania);  Christophe H. Schilling (San Diego, California)
ASSIGNEE(S) Genomatica, Inc. (San Diego, California)
INVENTOR(S) Mark J. Burk (San Diego, California);  Priti Pharkya (San Diego, California);  Stephen J. Van Dien (Encinitas, California);  Anthony P. Burgard (Bellenfonte, Pennsylvania);  Christophe H. Schilling (San Diego, California)
ABSTRACT The invention provides a method of producing acrylic acid. The method includes contacting fumaric acid with a sufficient amount of ethylene in the presence of a cross-metathesis transformation catalyst to produce about two moles of acrylic acid per mole of fumaric acid. Also provided is an acrylate ester. The method includes contacting fumarate diester with a sufficient amount of ethylene in the presence of a cross-metathesis transformation catalyst to produce about two moles of acrylate ester per mole of fumarate diester. An integrated process for process for producing acrylic acid or acrylate ester is provided which couples bioproduction of fumaric acid with metathesis transformation. An acrylic acid and an acrylate ester production also is provided.
FILED Friday, August 26, 2011
APPL NO 13/219423
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/40 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456081 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Yifan Zhang (Ann Arbor, Michigan);  Stephen R. Forrest (Ann Arbor, Michigan);  Mark Thompson (Los Angeles, California)
ASSIGNEE(S) The University of Southern California (Los Angeles, California);  The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Yifan Zhang (Ann Arbor, Michigan);  Stephen R. Forrest (Ann Arbor, Michigan);  Mark Thompson (Los Angeles, California)
ABSTRACT A first device is provided. The first device further comprises an organic light emitting device. The organic light emitting device further comprises an anode, a cathode, and an emissive layer disposed between the anode and the cathode. The emissive layer further comprises an organic host compound, an organic emitting compound capable of fluorescent emission at room temperature, and an organic dopant compound. The triplet energy of the dopant compound is lower than the triplet energy of the host compound. The dopant compound does not strongly absorb the fluorescent emission of the emitting compound.
FILED Friday, May 27, 2011
APPL NO 13/117926
ART UNIT 2879 — Optics
CURRENT CPC
Electric lamp and discharge devices
313/504
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US 08456313 Savignac et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Noel Felix Savignac (Albuquerque, New Mexico);  Leo S. Gomez (Albuquerque, New Mexico);  William Graham Yelton (Sandia Park, New Mexico);  Alex Robinson (Albuquerque, New Mexico);  Steven Limmer (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Noel Felix Savignac (Albuquerque, New Mexico);  Leo S. Gomez (Albuquerque, New Mexico);  William Graham Yelton (Sandia Park, New Mexico);  Alex Robinson (Albuquerque, New Mexico);  Steven Limmer (Albuquerque, New Mexico)
ABSTRACT This invention is a nuclear radiation-warning detector that measures impedance of silver-silver halide on an interdigitated electrode to detect light or radiation comprised of alpha particles, beta particles, gamma rays, X rays, and/or neutrons. The detector is comprised of an interdigitated electrode covered by a layer of silver halide. After exposure to alpha particles, beta particles, X rays, gamma rays, neutron radiation, or light, the silver halide is reduced to silver in the presence of a reducing solution. The change from the high electrical resistance (impedance) of silver halide to the low resistance of silver provides the radiation warning that detected radiation levels exceed a predetermined radiation dose threshold.
FILED Thursday, December 24, 2009
APPL NO 12/655173
ART UNIT 2685 — Selective Communication
CURRENT CPC
Communications: Electrical
340/620
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457941 Maranas et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) Costas D. Maranas (Port Matilda, Pennsylvania);  Anthony R. Burgard (State College, Pennsylvania);  Priti Pharkya (State College, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Costas D. Maranas (Port Matilda, Pennsylvania);  Anthony R. Burgard (State College, Pennsylvania);  Priti Pharkya (State College, Pennsylvania)
ABSTRACT A method for determining candidates for gene deletions and additions using a model of a metabolic network associated with an organism, the model includes a plurality of metabolic reactions defining metabolite relationships, the method includes selecting a bioengineering objective for the organism, selecting at least one cellular objective, forming an optimization problem that couples the at least one cellular objective with the bioengineering objective, and solving the optimization problem to yield at least one candidate.
FILED Tuesday, August 16, 2011
APPL NO 13/210484
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/11
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458244 Blocksome et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Michael A. Blocksome (Rochester, Minnesota);  Daniel A. Faraj (Rochester, Minnesota)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael A. Blocksome (Rochester, Minnesota);  Daniel A. Faraj (Rochester, Minnesota)
ABSTRACT A parallel computer including compute nodes, each including two reduction processing cores, a network write processing core, and a network read processing core, each processing core assigned an input buffer. Copying, in interleaved chunks by the reduction processing cores, contents of the reduction processing cores' input buffers to an interleaved buffer in shared memory; copying, by one of the reduction processing cores, contents of the network write processing core's input buffer to shared memory; copying, by another of the reduction processing cores, contents of the network read processing core's input buffer to shared memory; and locally reducing in parallel by the reduction processing cores: the contents of the reduction processing core's input buffer; every other interleaved chunk of the interleaved buffer; the copied contents of the network write processing core's input buffer; and the copied contents of the network read processing core's input buffer.
FILED Wednesday, August 15, 2012
APPL NO 13/585993
ART UNIT 2441 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/201
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458267 Chen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Dong Chen (Yorktown Heights, New York);  Philip Heidelberger (Yorktown Heights, New York);  Valentina Salapura (Yorktown Heights, New York);  Robert M. Senger (Yorktown Heights, New York);  Burkhard Steinmacher-Burow (Boeblingen, Germany);  Yutaka Sugawara (Yorktown Heights, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Dong Chen (Yorktown Heights, New York);  Philip Heidelberger (Yorktown Heights, New York);  Valentina Salapura (Yorktown Heights, New York);  Robert M. Senger (Yorktown Heights, New York);  Burkhard Steinmacher-Burow (Boeblingen, Germany);  Yutaka Sugawara (Yorktown Heights, New York)
ABSTRACT A method and apparatus for distributed parallel messaging in a parallel computing system. The apparatus includes, at each node of a multiprocessor network, multiple injection messaging engine units and reception messaging engine units, each implementing a DMA engine and each supporting both multiple packet injection into and multiple reception from a network, in parallel. The reception side of the messaging unit (MU) includes a switch interface enabling writing of data of a packet received from the network to the memory system. The transmission side of the messaging unit, includes switch interface for reading from the memory system when injecting packets into the network.
FILED Tuesday, January 26, 2010
APPL NO 12/693972
ART UNIT 2444 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/206
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458282 Chen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Dong Chen (Croton On Hudson, New York);  Alan Gara (Mount Kisco, New York);  Philip Heidelberger (Cortlandt Manor, New York);  Martin Ohmacht (Yorktown, New York);  Pavlos Vranas (Danville, California)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Dong Chen (Croton On Hudson, New York);  Alan Gara (Mount Kisco, New York);  Philip Heidelberger (Cortlandt Manor, New York);  Martin Ohmacht (Yorktown, New York);  Pavlos Vranas (Danville, California)
ABSTRACT A computing apparatus for reducing the amount of processing in a network computing system which includes a network system device of a receiving node for receiving electronic messages comprising data. The electronic messages are transmitted from a sending node. The network system device determines when more data of a specific electronic message is being transmitted. A memory device stores the electronic message data and communicating with the network system device. A memory subsystem communicates with the memory device. The memory subsystem stores a portion of the electronic message when more data of the specific message will be received, and the buffer combines the portion with later received data and moves the data to the memory device for accessible storage.
FILED Tuesday, June 26, 2007
APPL NO 11/768593
ART UNIT 2454 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/213
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458677 Gschwind
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Michael K. Gschwind (Chappaqua, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael K. Gschwind (Chappaqua, New York)
ABSTRACT Mechanisms for intermixing code are provided. Source code is received for compilation using an extended Application Binary Interface (ABI) that extends a legacy ABI and uses a different register configuration than the legacy ABI. First compiled code is generated based on the source code, the first compiled code comprising code for accommodating the difference in register configurations used by the extended ABI and the legacy ABI. The first compiled code and second compiled code are intermixed to generate intermixed code, the second compiled code being compiled code that uses the legacy ABI. The intermixed code comprises at least one call instruction that is one of a call from the first compiled code to the second compiled code or a call from the second compiled code to the first compiled code. The code for accommodating the difference in register configurations is associated with the at least one call instruction.
FILED Thursday, August 20, 2009
APPL NO 12/544258
ART UNIT 2197 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/140
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458684 Eichenberger et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Alexandre E. Eichenberger (Chappaqua, New York);  Alan Gara (Mount Kisco, New York);  Michael K. Gschwind (Chappaqua, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Alexandre E. Eichenberger (Chappaqua, New York);  Alan Gara (Mount Kisco, New York);  Michael K. Gschwind (Chappaqua, New York)
ABSTRACT Mechanisms are provided for inserting indicated instructions for tracking and indicating exceptions in the execution of vectorized code. A portion of first code is received for compilation. The portion of first code is analyzed to identify non-speculative instructions performing designated non-speculative operations in the first code that are candidates for replacement by replacement operation-and-indicate instructions that perform the designated non-speculative operations and further perform an indication operation for indicating any exception conditions corresponding to special exception values present in vector register inputs to the replacement operation-and-indicate instructions. The replacement is performed and second code is generated based on the replacement of the at least one non-speculative instruction. The data processing system executing the compiled code is configured to store special exception values in vector output registers, in response to a speculative instruction generating an exception condition, without initiating exception handling.
FILED Wednesday, August 19, 2009
APPL NO 12/543628
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/159
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458722 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Charles J. Archer (Rochester, Minnesota);  Michael A. Blocksome (Rochester, Minnesota);  Amanda E. Peters (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota);  Brian E. Smith (Rochester, Minnesota)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles J. Archer (Rochester, Minnesota);  Michael A. Blocksome (Rochester, Minnesota);  Amanda E. Peters (Rochester, Minnesota);  Joseph D. Ratterman (Rochester, Minnesota);  Brian E. Smith (Rochester, Minnesota)
ABSTRACT Methods, apparatus, and products are disclosed for thread selection during context switching on a plurality of compute nodes that includes: executing, by a compute node, an application using a plurality of threads of execution, including executing one or more of the threads of execution; selecting, by the compute node from a plurality of available threads of execution for the application, a next thread of execution in dependence upon power characteristics for each of the available threads; determining, by the compute node, whether criteria for a thread context switch are satisfied; and performing, by the compute node, the thread context switch if the criteria for a thread context switch are satisfied, including executing the next thread of execution.
FILED Monday, June 09, 2008
APPL NO 12/135604
ART UNIT 2195 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers and digital processing systems: Virtual machine task or process management or task management/control
718/108
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458811 Luber et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Erik J. Luber (Edmonton, Canada);  Colin Ophus (Berkeley, California);  David Mitlin (Sherwood Park, Canada);  Brian Olsen (Edmonton, Canada);  Christopher Harrower (Edmonton, Canada);  Velimir Radmilović (Piedmont, California)
ASSIGNEE(S) The Governors of the University of Alberta (Edmonton, Alberta, Canada);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Erik J. Luber (Edmonton, Canada);  Colin Ophus (Berkeley, California);  David Mitlin (Sherwood Park, Canada);  Brian Olsen (Edmonton, Canada);  Christopher Harrower (Edmonton, Canada);  Velimir Radmilović (Piedmont, California)
ABSTRACT An all-metal microdevice or nanodevice such as an atomic force microscope probe is manufactured from a copper-hafnium alloy thin film having an x-ray amorphous microstructure.
FILED Friday, March 25, 2011
APPL NO 13/072343
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM]
850/33
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE44266 Mayfield
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Stephen P. Mayfield (Cardiff, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Stephen P. Mayfield (Cardiff, California)
ABSTRACT The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.
FILED Friday, January 16, 1998
APPL NO 11/197730
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08454707 Ankem
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Sreeramamurthy Ankem (Silver Spring, Maryland)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Sreeramamurthy Ankem (Silver Spring, Maryland)
ABSTRACT The present invention relates to improved biomedical implantable material comprising a plurality of pores, of which one or more of the pores are interconnected below the surface of the material. The improved biomedical implantable material may be used in biomedical implant devices such as orthopedic implants, spinal implants, neurocranial implants, maxillofacial implants, and joint replacement implants. The present invention also relates to a method of preparing an improved biomedical implantable material, comprising subjecting an implantable material to a pore-forming treatment and optionally further subjecting the material to a surface-modifying treatment. The biomedical implantable material may be used in other applications, which as applications where two surfaces are contacted and bonding between the surfaces is required.
FILED Monday, April 05, 2010
APPL NO 12/754309
ART UNIT 3738 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Prosthesis
623/23.550
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455174 Kohl et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
National Science Foundation (NSF)
APPLICANT(S) Paul A. Kohl (Atlanta, Georgia);  Sue Ann Bidstrup-Allen (Atlanta, Georgia);  Clifford Lee Henderson (Douglasville, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Paul A. Kohl (Atlanta, Georgia);  Sue Ann Bidstrup-Allen (Atlanta, Georgia);  Clifford Lee Henderson (Douglasville, Georgia)
ABSTRACT Polymers, methods of use thereof, and methods of decomposition thereof, are provided. One exemplary polymer, among others, includes, a photodefinable polymer having a sacrificial polymer and a photoinitiator.
FILED Thursday, October 28, 2010
APPL NO 12/913807
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/270.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455392 Wachs et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil and Mechanical Systems (CMS)
APPLICANT(S) Israel E. Wachs (Bridgewater, New Jersey);  Elizabeth I. Ross-Medgaarden (West Grove, Pennsylvania);  Michael Sha-nang Wong (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas);  Lehigh University (Bethlehem, Pennsylvania)
INVENTOR(S) Israel E. Wachs (Bridgewater, New Jersey);  Elizabeth I. Ross-Medgaarden (West Grove, Pennsylvania);  Michael Sha-nang Wong (Houston, Texas)
ABSTRACT A new type of solid acid catalyst, which promises better catalytic performance than conventionally prepared supported metal oxides due to its precisely synthesized nanostructure has been described. The catalyst is nanoparticulate in form and is comprised of monolayers of tungstated zirconia of the formula, WOxZryO4-2y made by impregnating a support with zirconium and tungsten. The support catalyst is further characterized in having a tugsten monolayer between greater than 0001 W/nm2 to about 30 W/nm2.
FILED Friday, June 20, 2008
APPL NO 12/665692
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/308
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455844 Lear et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Kevin L. Lear (Fort Collins, Colorado);  Sean B. Pieper (Lincoln, Nebraska)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Kevin L. Lear (Fort Collins, Colorado);  Sean B. Pieper (Lincoln, Nebraska)
ABSTRACT A measurement system for use with fluorescent chemosensors has multiple stimulus light sources each coupled to at least one sensor. Multiple sensors each receiving light from a different light source connect to each of one or more photodetectors. A processing device drives the light sources in a time-division multiplexed manner, and reads the photodetector at an appropriate time for each sensor. The processing device calibrates the sensor readings and provides them in a way that is identified to the associated sensor.
FILED Thursday, March 11, 2010
APPL NO 12/722446
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/458.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455856 Hersee
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Stephen D. Hersee (Albuquerque, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Stephen D. Hersee (Albuquerque, New Mexico)
ABSTRACT Various embodiments provide materials and methods for integrating exemplary heterostructure field-effect transistor (HFET) driver circuit or thyristor driver circuit with LED structures to reduce or eliminate resistance and/or inductance associated with their conventional connections.
FILED Friday, April 01, 2011
APPL NO 13/078368
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456150 Shih et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Wan Y. Shih (Bryn Mawr, Pennsylvania);  Wei-Heng Shih (Bryn Mawr, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Wan Y. Shih (Bryn Mawr, Pennsylvania);  Wei-Heng Shih (Bryn Mawr, Pennsylvania)
ABSTRACT The invention is directed to a novel phase-shift detector capable of interfacing with an array of sensors. The detector is light-weight, portable and capable of fitting within the palm of a hand. The detector may be used in conjunction with a variety of diagnostic, biosensor and chemical sensor applications.
FILED Wednesday, January 30, 2008
APPL NO 12/524876
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/76.770
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456345 Baraniuk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Richard G. Baraniuk (Houston, Texas);  Jason N. Laska (Houston, Texas);  Petros T. Boufounos (Boston, Massachusetts);  Mark A. Davenport (Los Altos Hills, California)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Richard G. Baraniuk (Houston, Texas);  Jason N. Laska (Houston, Texas);  Petros T. Boufounos (Boston, Massachusetts);  Mark A. Davenport (Los Altos Hills, California)
ABSTRACT A method for recovering a signal by measuring the signal to produce a plurality of compressive sensing measurements, discarding saturated measurements from the plurality of compressive sensing measurements and reconstructing the signal from remaining measurements from the plurality of compressive sensing measurements. Alternatively, a method for recovering a signal comprising the steps of measuring a signal to produce a plurality of compressive sensing measurements, identifying saturated measurements in the plurality of compressive sensing measurements and reconstructing the signal from the plurality of compressive sensing measurements, wherein the recovered signal is constrained such that magnitudes of values corresponding to the identified saturated measurements are greater than a predetermined value.
FILED Wednesday, February 23, 2011
APPL NO 13/033212
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Coded data generation or conversion
341/155
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456736 Wise et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) Frank W. Wise (Ithaca, New York);  Shian Zhou (Rochester, New York);  Dimitre G. Ouzounov (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Frank W. Wise (Ithaca, New York);  Shian Zhou (Rochester, New York);  Dimitre G. Ouzounov (Ithaca, New York)
ABSTRACT To avoid harmful nonlinear effects in the amplification of short optical pulses, an initial pulse is divided into a sequence of lower-energy temporally spaced pulses that are otherwise identical to the original pulse. The low-intensity pulses are amplified and then recombined to create a final amplified output pulse.
FILED Monday, December 03, 2007
APPL NO 12/517092
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Optical: Systems and elements
359/341.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457453 Lipson et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Michal Lipson (Ithaca, New York);  Biswajeet Guha (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Michal Lipson (Ithaca, New York);  Biswajeet Guha (Ithaca, New York)
ABSTRACT Apparatus and methods that compensate for the thermally-induced drift of the resonance frequency of a closed-loop resonator include, in an exemplary embodiment, a waveguide-based Mach-Zehnder interferometer (MZI) and an overcoupled, waveguide-based microring resonator. The temperature-induced red-shifting ring resonance can be balanced by a spectral blueshift with temperature of the MZI. To stabilize the resonance of the ring at a given wavelength, the change in optical path lengths with temperature of the ring and the MZI should be equal and opposite. The interplay of nonlinear change in phase of ring resonator with temperature and linear change in phase of MZI with temperature, along with matching the period of this phase change, gives rise to perfect oscillation in the combined system resonance with temperature.
FILED Monday, November 01, 2010
APPL NO 12/916663
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457941 Maranas et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) Costas D. Maranas (Port Matilda, Pennsylvania);  Anthony R. Burgard (State College, Pennsylvania);  Priti Pharkya (State College, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Costas D. Maranas (Port Matilda, Pennsylvania);  Anthony R. Burgard (State College, Pennsylvania);  Priti Pharkya (State College, Pennsylvania)
ABSTRACT A method for determining candidates for gene deletions and additions using a model of a metabolic network associated with an organism, the model includes a plurality of metabolic reactions defining metabolite relationships, the method includes selecting a bioengineering objective for the organism, selecting at least one cellular objective, forming an optimization problem that couples the at least one cellular objective with the bioengineering objective, and solving the optimization problem to yield at least one candidate.
FILED Tuesday, August 16, 2011
APPL NO 13/210484
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/11
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458259 Karger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) David Karger (Cambridge, Massachusetts);  Eric Lehman (Cambridge, Massachusetts);  F. Thomson Leighton (Newtonville, Massachusetts);  Matthew Levine (Somerville, Massachusetts);  Daniel Lewin (Cambridge, Massachusetts);  Rina Panagrahy (Mountain View, California)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David Karger (Cambridge, Massachusetts);  Eric Lehman (Cambridge, Massachusetts);  F. Thomson Leighton (Newtonville, Massachusetts);  Matthew Levine (Somerville, Massachusetts);  Daniel Lewin (Cambridge, Massachusetts);  Rina Panagrahy (Mountain View, California)
ABSTRACT The invention relates to an apparatus for responding to data requests made by a client. The apparatus includes an input receiving a first data request that includes a sequence of nodes corresponding to a sequence of servers. The apparatus also includes decision logic determining whether the data specified in the data request is available on a selected server, and if the data is not available determining a next node from the sequence of nodes. The apparatus also includes a mapper mapping a server to the next node, and an output requesting the data by transmitting a second data request to the server mapped to the next node.
FILED Friday, December 23, 2011
APPL NO 13/336745
ART UNIT 2452 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/205
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US 08458556 Planjery et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Shiva K. Planjery (Tucson, Arizona);  Shashi Kiran Chilappagari (San Jose, California);  Bane Vasic (Tucson, Arizona);  David Declercq (Ableiges, France)
ASSIGNEE(S) STMicroelectronics, SA (Montrouge, France)
INVENTOR(S) Shiva K. Planjery (Tucson, Arizona);  Shashi Kiran Chilappagari (San Jose, California);  Bane Vasic (Tucson, Arizona);  David Declercq (Ableiges, France)
ABSTRACT In this invention, a new class of finite precision multilevel decoders for low-density parity-check (LDPC) codes is presented. These decoders are much lower in complexity compared to the standard belief propagation (BP) decoder. Messages utilized by these decoders are quantized to certain levels based on the number of bits allowed for representation in hardware. A message update function specifically defined as part of the invention, is used to determine the outgoing message at the variable node, and the simple min operation along with modulo 2 sum of signs is used at the check node. A general methodology is provided to obtain the multilevel decoders, which is based on reducing failures due to trapping sets and improving the guaranteed error-correction capability of a code. Hence these decoders improve the iterative decoding process on finite length graphs and have the potential to outperform the standard floating-point BP decoder in the error floor region. The description and apparatus of 3-bit decoders for column-weight three LDPC codes is also presented.
FILED Friday, October 08, 2010
APPL NO 12/900584
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/752
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National Aeronautics and Space Administration (NASA) 

US 08455583 Krishnamoorti et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Ramanan Krishnamoorti (Bellaire, Texas);  Cynthia A. Mitchell (Houston, Texas);  Jeffrey L. Bahr (Houston, Texas)
ASSIGNEE(S) University of Houston (Houston, Texas)
INVENTOR(S) Ramanan Krishnamoorti (Bellaire, Texas);  Cynthia A. Mitchell (Houston, Texas);  Jeffrey L. Bahr (Houston, Texas)
ABSTRACT The present invention is directed to carbon nanotube (CNT)/polymer composites, i.e., nanocomposites, wherein the CNTs in such nanocomposites are highly dispersed in a polymer matrix, and wherein the nanocomposites comprise a compatibilizing surfactant that interacts with both the CNTs and the polymer matrix. The present invention is also directed to methods of making these nanocomposites. In some such methods, the compatibilizing surfactant provides initial CNT dispersion and subsequent mixing with a polymer. The present invention is also directed to methods of using these nanocomposites in a variety of applications.
FILED Tuesday, August 02, 2005
APPL NO 11/659407
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
524/496
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455926 Harpold et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Dan N. Harpold (Beltsville, Maryland);  Hasso B. Niemann (Columbia, Maryland);  Brian G. Jamieson (Severna Park, Maryland);  Bernard A. Lynch (San Antonio, Texas)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Dan N. Harpold (Beltsville, Maryland);  Hasso B. Niemann (Columbia, Maryland);  Brian G. Jamieson (Severna Park, Maryland);  Bernard A. Lynch (San Antonio, Texas)
ABSTRACT Systems, methods and apparatus are provided through which in some embodiments a mass spectrometer micro-leak includes a number of channels fabricated by semiconductor processing tools and that includes a number of inlet holes that provide access to the channels.
FILED Thursday, September 23, 2010
APPL NO 12/889014
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Active solid-state devices
257/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456392 Ray et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) William Johnstone Ray (Fountain Hills, Arizona);  Mark D. Lowenthal (Gilbert, Arizona);  Neil O. Shotton (Perry, Florida);  Richard A. Blanchard (Los Altos, California);  Mark Allan Lewandowski (Tempe, Arizona);  Kirk A. Fuller (Madison, Alabama);  Donald Odell Frazier (Huntsville, Alabama)
ASSIGNEE(S) NthDegree Technologies Worldwide Inc (Tempe, Arizona);  The United States of America as represented by the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) William Johnstone Ray (Fountain Hills, Arizona);  Mark D. Lowenthal (Gilbert, Arizona);  Neil O. Shotton (Perry, Florida);  Richard A. Blanchard (Los Altos, California);  Mark Allan Lewandowski (Tempe, Arizona);  Kirk A. Fuller (Madison, Alabama);  Donald Odell Frazier (Huntsville, Alabama)
ABSTRACT The present invention provides a method of manufacturing an electronic apparatus, such as a lighting device having light emitting diodes (LEDs) or a power generating device having photovoltaic diodes. The exemplary method includes forming at least one first conductor coupled to a base; coupling a plurality of substantially spherical substrate particles to the at least one first conductor; converting the substrate particles into a plurality of substantially spherical diodes; forming at least one second conductor coupled to the substantially spherical diodes; and depositing or attaching a plurality of substantially spherical lenses suspended in a first polymer. The lenses and the suspending polymer have different indices of refraction. In some embodiments, the lenses and diodes have a ratio of mean diameters or lengths between about 10:1 and 2:1. In various embodiments, the forming, coupling and converting steps are performed by or through a printing process.
FILED Tuesday, September 15, 2009
APPL NO 12/560355
ART UNIT 2695 — Semiconductors/Memory
CURRENT CPC
Computer graphics processing and selective visual display systems
345/82
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08456393 Ray et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) William Johnstone Ray (Fountain Hills, Arizona);  Mark D. Lowenthal (Gilbert, Arizona);  Neil O. Shotton (Perry, Florida);  Richard A. Blanchard (Los Altos, California);  Mark Allan Lewandowski (Tempe, Arizona);  Kirk A. Fuller (Madison, Alabama);  Donald Odell Frazier (Huntsville, Alabama)
ASSIGNEE(S) NthDegree Technologies Worldwide Inc (Tempe, Arizona);  The United States of America as represented by the United States National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) William Johnstone Ray (Fountain Hills, Arizona);  Mark D. Lowenthal (Gilbert, Arizona);  Neil O. Shotton (Perry, Florida);  Richard A. Blanchard (Los Altos, California);  Mark Allan Lewandowski (Tempe, Arizona);  Kirk A. Fuller (Madison, Alabama);  Donald Odell Frazier (Huntsville, Alabama)
ABSTRACT The present invention provides a method of manufacturing an electronic apparatus, such as a lighting device having light emitting diodes (LEDs) or a power generating device having photovoltaic diodes. The exemplary method includes forming at least one first conductor coupled to a base; coupling a plurality of substrate particles to the at least one first conductor; converting the plurality of substrate particles into a plurality of diodes; forming at least one second conductor coupled to the plurality of spherical diodes; and depositing or attaching a plurality of substantially spherical lenses suspended in a first polymer, with the lenses and the suspending polymer having different indices of refraction. In some embodiments, the lenses and diodes have a ratio of mean diameters or lengths between about 10:1 and 2:1. In various embodiments, the forming, coupling and converting steps are performed by or through a printing process.
FILED Tuesday, September 15, 2009
APPL NO 12/560364
ART UNIT 2695 — Semiconductors/Memory
CURRENT CPC
Computer graphics processing and selective visual display systems
345/82
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08457939 Rodriguez et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Langley Research Center (LaRC)
APPLICANT(S) David L. Rodriguez (Palo Alto, California);  Peter Sturdza (Redwood City, California)
ASSIGNEE(S) Aerion Corporation (Reno, Nevada)
INVENTOR(S) David L. Rodriguez (Palo Alto, California);  Peter Sturdza (Redwood City, California)
ABSTRACT Fluid-flow simulation over a computer-generated aircraft surface is generated using inviscid and viscous simulations. A fluid-flow mesh of fluid cells is obtained. At least one inviscid fluid property for the fluid cells is determined using an inviscid fluid simulation that does not simulate fluid viscous effects. A set of intersecting fluid cells that intersects the aircraft surface are identified. One surface mesh polygon of the surface mesh is identified for each intersecting fluid cell. A boundary-layer prediction point for each identified surface mesh polygon is determined. At least one boundary-layer fluid property for each boundary-layer prediction point is determined using the at least one inviscid fluid property of the corresponding intersecting fluid cell and a boundary-layer simulation that simulates fluid viscous effects. At least one updated fluid property for at least one fluid cell is determined using the at least one boundary-layer fluid property and the inviscid fluid simulation.
FILED Thursday, December 30, 2010
APPL NO 12/982744
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/9
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08458649 Bouillet et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New Jersey);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New Jersey);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ABSTRACT A method, including: receiving a software requirement; and constructing a workflow template that can satisfy the software requirement, wherein the workflow template comprises a plurality of processing stages, wherein each processing stage includes at least one component class and each component class includes at least one component, and wherein an output of each processing stage is described by a processing goal pattern that is described by a set of tags and facets.
FILED Wednesday, October 15, 2008
APPL NO 12/252156
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/106
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458650 Andrade et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Henrique Andrade (Croton-on-Hudson, New York);  Bugra Gedik (White Plains, New York);  Gabriela Jacques da Silva (Champaign, Illinois);  Kun-Lung Wu (Yorktown Heights, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Henrique Andrade (Croton-on-Hudson, New York);  Bugra Gedik (White Plains, New York);  Gabriela Jacques da Silva (Champaign, Illinois);  Kun-Lung Wu (Yorktown Heights, New York)
ABSTRACT In one embodiment, the invention comprises partial fault tolerant stream processing applications. One embodiment of a method for implementing partial fault tolerance in a stream processing application comprising a plurality of stream operators includes: defining a quality score function that expresses how well the application is performing quantitatively, injecting a fault into at least one of the plurality of operators, assessing an impact of the fault on the quality score function, and selecting at least one partial fault-tolerant technique for implementation in the application based on the quantitative metric-driven assessment.
FILED Monday, March 29, 2010
APPL NO 12/748633
ART UNIT 2198 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/106
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458685 Greyzck
FUNDED BY
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) Terry D. Greyzck (Eagan, Minnesota)
ASSIGNEE(S) Cray Inc. (Seattle, Washington)
INVENTOR(S) Terry D. Greyzck (Eagan, Minnesota)
ABSTRACT A system and method of compiling program code, wherein the program code includes an operation on an array of data elements stored in memory of a computer system. The program code is scanned for an equation which may have recurring data points. The equation is then replaced with vectorized machine executable code, wherein the machine executable code comprises a nested loop and wherein the nested loop comprises an exterior loop and a virtual interior loop. The exterior loop decomposes the equation into a plurality of loops of length N, wherein N is an integer greater than one. The virtual interior loop executes vector operations corresponding to the N length loop to form a result vector resident in memory, wherein the virtual interior loop includes a vector atomic memory operation (AMO) instruction.
FILED Friday, June 12, 2009
APPL NO 12/483672
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/160
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458720 Bansal et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Nikhil Bansal (Yorktown Heights, New York);  Kirsten Weale Hildrum (Hawthorne, New York);  Deepak Rajan (Fishkill, New York);  Joel Leonard Wolf (Katonah, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Nikhil Bansal (Yorktown Heights, New York);  Kirsten Weale Hildrum (Hawthorne, New York);  Deepak Rajan (Fishkill, New York);  Joel Leonard Wolf (Katonah, New York)
ABSTRACT A system and method for choosing non-continual jobs to run in a stream-based distributed computer system includes determining a total amount of resources to be consumed by non-continual jobs. A priority threshold is determined above which jobs will be accepted, below which jobs will be rejected. Overall penalties are minimized relative to the priority threshold based on estimated completion times of the jobs. System constraints are applied to ensure that jobs meet set criteria such that a plurality of non-continual jobs are scheduled which consider the system constraints and minimize overall penalties using available resources.
FILED Friday, August 17, 2007
APPL NO 11/840556
ART UNIT 2199 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers and digital processing systems: Virtual machine task or process management or task management/control
718/107
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 08455412 Bredsguard
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S) Jakob Bredsguard (Irvine, California)
ASSIGNEE(S) Biosynthetic Technologies, LLC (Irvine, California)
INVENTOR(S) Jakob Bredsguard (Irvine, California)
ABSTRACT Provided herein are compounds, including those of the Formula II
in which n is an integer equal to or greater than 1; R2, is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R3, and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Also provided are compositions containing such compounds and methods of making both compounds and compositions thereof.
FILED Wednesday, August 31, 2011
APPL NO 13/223008
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Solid anti-friction devices, materials therefor, lubricant or separant compositions for moving solid surfaces, and miscellaneous mineral oil compositions
58/465
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08455666 Laszlo et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Joseph A. Laszlo (Peoria, Illinois);  David L. Compton (Peoria, Illinois);  Kervin O. Evans (Chillicothe, Illinois)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Joseph A. Laszlo (Peoria, Illinois);  David L. Compton (Peoria, Illinois);  Kervin O. Evans (Chillicothe, Illinois)
ABSTRACT Esters of lipoic acid with a glyceride are produced in high yield by lipase catalyzed transesterification. The esters are generally characterized by Formula 1:
wherein at least one but no more than two of R1, R2, and R3 are a lipoic acid derivative selected from a lipoate moiety of the formula:
or a dihydrolipoate moiety of the formula
and the other of the R1, R2, and R3 are independently selected from C4 to C24 fatty acid moieties or OH, with the proviso that at least one of the R1, R2, and R3 is a fatty acid moiety.
FILED Friday, September 02, 2011
APPL NO 13/224565
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
549/39
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United States Postal Service (USPS) 

US 08457978 Williams et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) David E Williams (Stafford, Virginia);  Stephen J McElroy (Manassas, Virginia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) David E Williams (Stafford, Virginia);  Stephen J McElroy (Manassas, Virginia)
ABSTRACT Systems and methods for creating in a facility on-demand routes for powered industrial vehicles to transport cargo efficiently. In one embodiment, an on-demand route generation module receives receiving a request to move cargo. The module analyzes data about the current location, the current tasking, and the driver availability of PIVs in operation. Based on the information, the module creates an on-demand route through the facility and sends a notification to an assigned PIV to pick up the cargo and carry it on the defined on-demand route.
FILED Monday, April 11, 2011
APPL NO 13/084489
ART UNIT 3629 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08458199 Garey
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) Ronald Garey (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Ronald Garey (Washington, District of Columbia)
ABSTRACT Methods and systems consistent with this invention manage a database of delivery destination information. Such methods and systems identify an item to be delivered to a destination; determine a batch of items for delivery having the item to be delivered to the destination; determine when the batch of items has been delivered; and update the database to indicate a delivery of the item destined to the destination after determining when the batch of items has been delivered.
FILED Tuesday, May 15, 2007
APPL NO 11/798516
ART UNIT 2167 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/752
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 08453773 Hill et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Transit Administration (FTA)
APPLICANT(S) Dale Hill (Evergreen, Colorado);  Michael Walker (Thornton, Colorado);  Shaun Onorato (Superior, Colorado);  Donald Morris (Conifer, Colorado);  Stephen Misencik (Raleigh, North Carolina);  John Winkel (Thornton, Colorado)
ASSIGNEE(S) Proterra Inc (Greenville, South Carolina)
INVENTOR(S) Dale Hill (Evergreen, Colorado);  Michael Walker (Thornton, Colorado);  Shaun Onorato (Superior, Colorado);  Donald Morris (Conifer, Colorado);  Stephen Misencik (Raleigh, North Carolina);  John Winkel (Thornton, Colorado)
ABSTRACT The invention provides for a high occupancy or heavy-duty vehicle with a battery propulsion power source, which may include lithium titanate batteries. The vehicle may be all-battery or may be a hybrid, and may have a composite body. The vehicle battery system may be housed within the floor of the vehicle and may have different groupings and arrangements.
FILED Friday, June 26, 2009
APPL NO 12/459074
ART UNIT 3618 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 16/04 (20130101)

Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 10/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 08455537 Welsh et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S) William J. Welsh (Princeton, New Jersey);  Ching Y. Wang (Cincinnati, Ohio);  Ni Ai (Piscataway, New Jersey)
ASSIGNEE(S) University of Medicine and Dentistry of New Jersey (Somerset, New Jersey)
INVENTOR(S) William J. Welsh (Princeton, New Jersey);  Ching Y. Wang (Cincinnati, Ohio);  Ni Ai (Piscataway, New Jersey)
ABSTRACT A method for preventing, diagnosing, or treating a condition mediated by an estrogen receptor by administering to a patient in need thereof an effective amount of a compound of formula I, II, or a combination thereof: wherein R1, R3, R4, and R5 are independently selected from H, OH, and ORa; R2 is selected from H, OH, and (C═O) (C1-7)alkyl; Ra is (C1-7)alkyl or (C═O)(C1-7)alkyl; or a derivative of the compound selected from N-oxide derivatives, prodrug derivatives, protected derivatives, isomers, and mixtures of isomers of the compound; or a pharmaceutically acceptable salt or solvate of the compound or the derivative. Compounds of formula I and II and pharmaceuticals compositions thereof are also presented.
FILED Tuesday, June 21, 2011
APPL NO 13/165431
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/417
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 08456729 Brown et al.
FUNDED BY
U.S. State Government
State of Oregon
APPLICANT(S) Gordon Z. Brown (Eugene, Oregon);  Tomoko C. Sekiguchi (Eugene, Oregon);  Thomas D. Northcutt (Springfield, Oregon);  Jeffrey A. Kline (Eugene, Oregon);  Dylan M. Lamar (Portland, Oregon)
ASSIGNEE(S) The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon)
INVENTOR(S) Gordon Z. Brown (Eugene, Oregon);  Tomoko C. Sekiguchi (Eugene, Oregon);  Thomas D. Northcutt (Springfield, Oregon);  Jeffrey A. Kline (Eugene, Oregon);  Dylan M. Lamar (Portland, Oregon)
ABSTRACT An automatic daylighting method adjusts a window covering to block direct sunlight from entering the room through a window when the exterior sky condition is a sunny sky state and, subject to blocking direct sunlight, provides a desired daylighting interior light illuminance level and, if possible, a desired interior solar heat gain through the window. To prevent window covering oscillation, a delay may be used when the sky condition changes from a sunny to overcast state. The covering control may be based on various factors including interior light illuminance entering the window, a room heating or to cooling mode, whether the room is occupied by people, whether occupants have manually operated an adjustable window covering, and the exterior sky condition. The method may also detect an interior temperature level, e.g., to determine a heating or cooling mode of the room.
FILED Wednesday, July 07, 2010
APPL NO 12/803888
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/275
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08455829 Bluzer
FUNDED BY
APPLICANT(S) Nathan Bluzer (Rockville, Maryland)
ASSIGNEE(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S) Nathan Bluzer (Rockville, Maryland)
ABSTRACT Electro-thermal feedback is utilized for reducing the effective thermal conductance between the detector stage of a bolometer pixel in a thermal radiation sensor assembly and the environment through its mechanical support structure and electrical interconnects, thereby coming closer to achieving thermal conductance limited primarily through photon radiation. Minimization of the effective thermal conductance associated with the mechanical support structure and electrical interconnects is achieved by electro-thermal feedback that adjusts the temperature of an intermediate stage and the mechanical support structure and electrical interconnects, connecting it to the detector stage, to equal the temperature of the bolometer pixel's detector stage (i.e., by active thermal isolation). Increased temperature sensitivity is preferably achieved through temperature sensing with reverse biased Schottky diodes connected in series.
FILED Tuesday, January 26, 2010
APPL NO 12/693731
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/339.30
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 04, 2013.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130604.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital