FedInvent™ Patents
Patent Details for Tuesday, June 11, 2013
This page was updated on Monday, March 27, 2023 at 03:47 AM GMT
Department of Defense (DOD)
| US 08458946 | Pintsch |
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| FUNDED BY |
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| APPLICANT(S) | Matas Victor Pintsch (Cresco, Pennsylvania) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Matas Victor Pintsch (Cresco, Pennsylvania) |
| ABSTRACT | An adapter for connecting a bipod to a Picatinny rail of a firearm may include a base having upper and lower portions. The upper portion may include a generally planar surface with longitudinal edges. The lower portion may include a cylinder having a through bore. First and second support members may be disposed along the longitudinal edges. The first support member may define a female mating configuration of one side of the Picatinny rail. A locking bar may be detachably connected to the upper portion of the base. The locking bar may have an interior surface. A leaf spring may be fixed to an underside of the upper portion of the base. The interior surface of the locking bar and the second support member may define a female mating configuration of another side of the Picatinny rail. |
| FILED | Friday, December 16, 2011 |
| APPL NO | 13/327877 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/94 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08458976 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Winnie W Chen (Huntington Beach, California); Edward A Zadorozny (Redondo Beach, California); Conley S Thatcher (Placentia, California); Jonathan D Embler (Huntington Beach, California); Leanne L Lehman (Aliso Viejo, California); Thomas Pinney (Huntington Beach, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Winnie W Chen (Huntington Beach, California); Edward A Zadorozny (Redondo Beach, California); Conley S Thatcher (Placentia, California); Jonathan D Embler (Huntington Beach, California); Leanne L Lehman (Aliso Viejo, California); Thomas Pinney (Huntington Beach, California) |
| ABSTRACT | A blanket assembly includes a shear fabric and an attachment frame wrapped in the shear fabric. A thermal protection blanket is carried by the shear fabric. |
| FILED | Friday, October 16, 2009 |
| APPL NO | 12/580478 |
| ART UNIT | 3635 — Static Structures, Supports and Furniture |
| CURRENT CPC | Static structures 052/404.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459036 | Baker |
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| FUNDED BY |
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| APPLICANT(S) | Von David Baker (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Von David Baker (Indianapolis, Indiana) |
| ABSTRACT | A nozzle is provided that can be used as part of an aircraft engine. In one form the nozzle includes an inner cowl and an outer cowl. The inner cowl can be actuated to a variety of positions. The outer cowl is piggybacked on the inner cowl and is initially retained in first position relative to the inner cowl with an outer cowl actuator. The outer cowl actuator can be commanded to release the outer cowl so that the outer cowl can be moved to a second position relative to the inner cowl. In one form the outer cowl actuator is an explosive bolt and a spring is provided to urge the outer cowl to the second position. |
| FILED | Monday, November 30, 2009 |
| APPL NO | 12/627625 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/771 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459123 | Stievater et al. |
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| FUNDED BY |
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| APPLICANT(S) | Todd H. Stievater (Arlington, Virginia); William S Rabinovich (Silver Spring, Maryland); Nicolas A Papanicolaou (Potomac, Maryland); Robert Bass (Columbia, Maryland); Jennifer L Stepnowski (Alexandria, Virginia); R Andrew McGill (Lorton, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Todd H. Stievater (Arlington, Virginia); William S Rabinovich (Silver Spring, Maryland); Nicolas A Papanicolaou (Potomac, Maryland); Robert Bass (Columbia, Maryland); Jennifer L Stepnowski (Alexandria, Virginia); R Andrew McGill (Lorton, Virginia) |
| ABSTRACT | Micro-opto-mechanical chemical sensors and methods for simultaneously detecting and discriminating between a variety of vapor-phase analytes. One embodiment of the sensor is a photonic microharp chemical sensor with an array of closely spaced microbridges, each differing slightly in length and coated with a different sorbent polymer. The microbridges can be excited photothermally, and the microbridges can be optically interrogated using microcavity interferometry. Other actuation methods include piezoelectric, piezoresistive, electrothermal, and magnetic. Other read-out techniques include using a lever arm and other interferometric techniques. |
| FILED | Tuesday, September 29, 2009 |
| APPL NO | 12/569691 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/657 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459167 | Gonzalez |
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| FUNDED BY |
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| APPLICANT(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
| ABSTRACT | An armor structure for a vehicle underbody. The armor structure includes an inner plate that is mounted proximate to the vehicle underbody, the inner plate having a plurality of first openings; and an outer plate that is mounted distal to the vehicle underbody, the outer plate having a plurality of second openings. The inner plate and the outer plate are substantially parallel and separated by a spacing. The inner plate and the outer plate each have substantially equal V bends at an obtuse angle, and the V bends in the inner plate and the outer plate are aligned. When an underbody blast event is encountered by the vehicle, the outer plate is forced towards, and substantially against the inner plate such that fluid communication via each of the first openings is reduced or prevented. |
| FILED | Thursday, February 14, 2013 |
| APPL NO | 13/767412 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/36.20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459279 | Jermyn |
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| FUNDED BY |
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| APPLICANT(S) | Richard A. Jermyn (Panama City, Florida) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Richard A. Jermyn (Panama City, Florida) |
| ABSTRACT | A spray nozzle tip adapter for cleaning a paint spray nozzle includes a rigid body member having an inlet port having annular sealing surfaces on one side, an exit port having annular sealing surfaces on another side and a passage connecting the inlet port and the exit port. The inlet port is shaped and sized to frictionally engage in a sealed relationship differently sized dispensing tubes of pressurized liquid solvent cans, and the exit port is shaped and sized to frictionally engage and retain a tubular inlet of a spray paint nozzle in a sealed relationship. The passage is shaped and sized to control a sealed flow of liquid to the nozzle and has a tapered region connected to the exit port to frictionally engage and retain a tubular inlet of a spray paint nozzle in a sealed relationship. |
| FILED | Friday, September 03, 2010 |
| APPL NO | 12/807376 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Cleaning and liquid contact with solids 134/114 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459413 | Gmirya et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yuriy Gmirya (Woodbridge, Connecticut); Mikhail Gelfand (Milford, Connecticut) |
| ASSIGNEE(S) | Sirkorsky Aircraft Corporation (Stratford, Connecticut) |
| INVENTOR(S) | Yuriy Gmirya (Woodbridge, Connecticut); Mikhail Gelfand (Milford, Connecticut) |
| ABSTRACT | A lubrication system includes an external pump system which pumps air out of the housing and develop negative pressure therein in response to a loss of lubrication condition. The negative pressure operates as an air lock to minimize or prevent lubricating oil loss from the housing while an internal lubrication system continues to distribute lubricating oil—which although now increasing in temperature—still operates to lubricate the gearbox components. For further ballistic tolerance, the housing is a compound housing that reduces or closes the penetration and further minimizes lubricating oil and negative pressure loss. The housing may be still further hardened by an armor layer. |
| FILED | Friday, January 19, 2007 |
| APPL NO | 12/522268 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Lubrication 184/6.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459911 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | Robert M. Kim (Lyndhurst, New Jersey); Frank C. Chan (Parsippany, New Jersey); Robert J. Middleton (Ann Arbor, Michigan); Robert M. Forrester (Lake Hopatcong, New Jersey); Bryan Anderson (Andover, New Jersey); Robert H. Holt (Franklin, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert M. Kim (Lyndhurst, New Jersey); Frank C. Chan (Parsippany, New Jersey); Robert J. Middleton (Ann Arbor, Michigan); Robert M. Forrester (Lake Hopatcong, New Jersey); Bryan Anderson (Andover, New Jersey); Robert H. Holt (Franklin, New Jersey) |
| ABSTRACT | Locking mechanisms and assemblies for securing cargo to a transportation platform without requiring the use of strapping or equivalent. Advantageously, the locking mechanism may be integrated into a container such that each container may be interlocked with an underlying and/or overlying container. Autolocking variations to the locking mechanism provide a more automated, secure and less labor intensive way to secure cargo. |
| FILED | Friday, September 09, 2011 |
| APPL NO | 13/228951 |
| ART UNIT | 3612 — Printing/Measuring and Testing |
| CURRENT CPC | Freight accommodation on freight carrier 410/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459936 | Damgaard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jocelyn Charis Damgaard (Vernon, Connecticut); Steven D. Roberts (Moodus, Connecticut); Timothy Dale (Manchester, Connecticut); Richard W. Monahan (Farmington, Connecticut); David C. Pimenta (Rocky Hill, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Jocelyn Charis Damgaard (Vernon, Connecticut); Steven D. Roberts (Moodus, Connecticut); Timothy Dale (Manchester, Connecticut); Richard W. Monahan (Farmington, Connecticut); David C. Pimenta (Rocky Hill, Connecticut) |
| ABSTRACT | A system includes a gas turbine engine, a nozzle structure located adjacent to the gas turbine engine, a flexible annular seal linking the gas turbine engine and the nozzle structure, the flexible annular seal having a plurality of corrugate sections arranged about a centerline, and a connection device secured to the gas turbine engine and to the nozzle structure. The connection device is adjustable to select a length of the flexible annular seal measured along the centerline. |
| FILED | Thursday, June 30, 2011 |
| APPL NO | 13/173522 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460003 | Bevan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas E. Bevan (Atlanta, Georgia); Alex Hill (Marietta, Georgia) |
| ASSIGNEE(S) | K-Force Government Solutions (Fairfax, Virginia) |
| INVENTOR(S) | Thomas E. Bevan (Atlanta, Georgia); Alex Hill (Marietta, Georgia) |
| ABSTRACT | An anthropomorphic training device for training of military and civilians in emergency medical care is presented. Such training devices provide stimuli to cue emergency medical personnel to perform required treatments, and are able to withstand simulated field medical training conditions. The devices provide realistic simulation of wounds, human anatomy and phenomena associated with traumatic injury (e.g. bleeding) and to provide immediate stimulus feedback on the success of the medical procedures. The simulation also provides realism sufficient to induce emotional response in the trainee, so that emotional responses can be extinguished or reduced prior to treatment of an actual injured patient. |
| FILED | Friday, July 09, 2010 |
| APPL NO | 12/833585 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Education and demonstration 434/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460409 | Hartvigsen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joseph J. Hartvigsen (Kaysville, Utah); S. Elangovan (South Jordan, Utah); Piotr Czernichowski (Layton, Utah); Michele Hollist (South Jordan, Utah) |
| ASSIGNEE(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Joseph J. Hartvigsen (Kaysville, Utah); S. Elangovan (South Jordan, Utah); Piotr Czernichowski (Layton, Utah); Michele Hollist (South Jordan, Utah) |
| ABSTRACT | A reformer is disclosed that includes a plasma zone to receive a pre-heated mixture of reactants and ionize the reactants by applying an electrical potential thereto. A first thermally conductive surface surrounds the plasma zone and is configured to transfer heat from an external heat source into the plasma zone. The reformer further includes a reaction zone to chemically transform the ionized reactants into synthesis gas comprising hydrogen and carbon monoxide. A second thermally conductive surface surrounds the reaction zone and is configured to transfer heat from the external heat source into the reaction zone. The first thermally conductive surface and second thermally conductive surface are both directly exposed to the external heat source. A corresponding method and system are also disclosed and claimed herein. |
| FILED | Friday, August 07, 2009 |
| APPL NO | 12/537953 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Gas: Heating and illuminating 048/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460428 | Lou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jun Lou (Houston, Texas); Yongjie Zhan (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jun Lou (Houston, Texas); Yongjie Zhan (Houston, Texas) |
| ABSTRACT | In various embodiments, methods for synthesizing single-crystalline zero-valent metal nanorings, such as single-crystalline copper nanorings, are described herein. The methods include providing a solution containing a metal cation, a complexing agent bound to the metal cation, thereby forming a metal complex that is at least partially soluble in the solution, and a reducing agent operable for reducing the metal complex to a zero-valent metal and then heating the solution for a sufficient time and at a sufficient temperature until zero-valent metal nanorings form. The solution may be an aqueous solution in an embodiment. Single-crystalline metal nanorings produced by the methods described herein may have a diameter less than about 100 μm and a wall thickness between about 10 nm and about 500 nm. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/771629 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460646 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Riyi Shi (West Lafayette, Indiana); Richard B. Borgens (Delphi, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Riyi Shi (West Lafayette, Indiana); Richard B. Borgens (Delphi, Indiana) |
| ABSTRACT | To achieve, an in vivo repair of injured mammalian nerve tissue, an effective amount of a biomembrane fusion agent is administered to the injured nerve tissue. The application of the biomembrane fusion agent may be performed by directly contacting the agent with the nerve tissue at the site of the injury. Alternatively, the biomembrane fusion agent is delivered to the site of the injury through the blood supply after administration of the biomembrane fusion agent to the patient. The administration is preferably by parenteral administration including intravascular, intramuscular, subcutaneous, or intraperitoneal injection of an effective quantity of the biomembrane fusion agent so that an effective amount is delivered to the site of the nerve tissue injury. |
| FILED | Thursday, July 23, 2009 |
| APPL NO | 12/508184 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460785 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ilsoon Lee (Okemos, Michigan); Troy R. Hendricks (Knoxville, Tennessee) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Ilsoon Lee (Okemos, Michigan); Troy R. Hendricks (Knoxville, Tennessee) |
| ABSTRACT | Methods to control and prevent polymer films from buckling are provided. Buckled morphologies are created by thermally cycling or mechanically compressing a substrate such as poly(dimethylsiloxane) (PDMS) coated with a polyelectrolyte multilayer film. By varying the dimensions of the surface topography relative to the buckling wavelength (e.g., pattern size is less than, equal to, and greater than the buckling wavelength) the orientation and the local morphology of the buckled films is controlled. Based on the information obtained, we demonstrate how to alleviate the unavoidable buckling by incorporating nanoparticles into the film. In addition, we studied the effect of the silica layer that results from oxygen plasma treatment and the critical temperature for permanent film buckling. |
| FILED | Thursday, November 15, 2007 |
| APPL NO | 12/515155 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460795 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence G. Anderson (Allison Park, Pennsylvania); Paul H. Lamers (Allison Park, Pennsylvania); Stephen G. McQuown (Cheswick, Pennsylvania) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Lawrence G. Anderson (Allison Park, Pennsylvania); Paul H. Lamers (Allison Park, Pennsylvania); Stephen G. McQuown (Cheswick, Pennsylvania) |
| ABSTRACT | The present invention is directed to curable film-forming compositions comprising: a) a curing agent; and b) a film-forming material comprising a fluoropolymer, a polymer having functional groups, and a plurality of particles comprising fillers and/or nanoscale particles having an average particle size ranging from 1 to less than 1000 nanometers prior to incorporation into the composition; wherein 20 to 30 percent by weight of the film-forming material of b) comprises the fluoropolymer. In certain embodiments, after application to a substrate as a coating and after curing, the cured composition demonstrates burnish resistance and an 85° gloss of less than 50. Multi-component composite coating compositions are also provided. |
| FILED | Monday, February 11, 2008 |
| APPL NO | 12/028988 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Stock material or miscellaneous articles 428/421 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460796 | Sherman |
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| FUNDED BY |
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| APPLICANT(S) | Andrew J. Sherman (Kirtland Hills, Ohio) |
| ASSIGNEE(S) | Mesocoat, Inc. (Euclid, Ohio) |
| INVENTOR(S) | Andrew J. Sherman (Kirtland Hills, Ohio) |
| ABSTRACT | A composite body that is spall resistant and comprises a substantially discontinuous cermet phase in a substantially continuous metal rich matrix phase. The composite body is typically bonded to a substrate to form a hardfacing on the substrate. The composite body exhibits ductile phase toughening with a strain to failure of at least about 2 percent, a modulus of elasticity of less than about 46 million pounds per square inch, and a density of less than about 7 grams per cubic centimeter. The metal rich matrix phase between the ceramic rich regions in the composite body has an average minimum span of about 0.5 to 8 microns to allow ductility in the composite body. The composite body has a Vicker's hardness number of greater than approximately 650. The discontinuous cermet phase is in the form of ceramic rich regions embedded within the composite body, and it includes ceramic particles and a cermet binder. The ceramic particles having a Moh's hardness of at least approximately 7.5, a modulus of elasticity of less than approximately 46 million pounds per square inch, and an average particle size of from about 0.1 to 10 microns. The ceramic rich regions exhibit high hardness as compared with the matrix phase. |
| FILED | Wednesday, February 03, 2010 |
| APPL NO | 12/699779 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/472 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460870 | Zocchi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Giovanni Zocchi (Los Angeles, California); Brian Choi (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Giovanni Zocchi (Los Angeles, California); Brian Choi (Los Angeles, California) |
| ABSTRACT | A method of altering the conformation of a polypeptide having a known three-dimensional structure is described. The method comprises attaching a first end of a polymer to a first portion of the polypeptide, attaching a second end of the polymer to a second portion of the polypeptide, and altering the mechanical tension of the polymer, thereby altering the conformation of the polypeptide. The alteration of the conformation of the polypeptide may increase or decrease the binding affinity of the polypeptide for a substrate bound by the polypeptide, or alter the catalytic rate of an enzyme. Typically, the polymer is a polynucleotide or polypeptide. |
| FILED | Wednesday, July 20, 2011 |
| APPL NO | 13/187351 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460878 | Walt et al. |
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| FUNDED BY |
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| APPLICANT(S) | David R. Walt (Boston, Massachusetts); David M. Rissin (Medford, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Tufts College (Boston, Massachusetts) |
| INVENTOR(S) | David R. Walt (Boston, Massachusetts); David M. Rissin (Medford, Massachusetts) |
| ABSTRACT | Arrays of single cells and methods of producing an array of single cells are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single cell capture, detection and quantitation. |
| FILED | Friday, February 16, 2007 |
| APPL NO | 11/707383 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460879 | Walt et al. |
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| FUNDED BY |
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| APPLICANT(S) | David R. Walt (Boston, Massachusetts); David M. Rissin (Medford, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Tufts College (Boston, Massachusetts) |
| INVENTOR(S) | David R. Walt (Boston, Massachusetts); David M. Rissin (Medford, Massachusetts) |
| ABSTRACT | Arrays of single molecules and methods of producing an array of single molecules are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single molecule detection and quantitation. |
| FILED | Friday, February 16, 2007 |
| APPL NO | 11/707385 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460907 | Walker et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jeremy P. Walker (Oakmont, Pennsylvania); Anna M. Leech (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | ICx-Agentase (Pittsburg, Pennsylvania) |
| INVENTOR(S) | Jeremy P. Walker (Oakmont, Pennsylvania); Anna M. Leech (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention provides a thermoresponsive nanoparticle useful for the stabilization of enzymes in environments having a temperature greater than thirty degrees Centigrade. The thermoresponsive nanoparticle has (a) a functionalized enzyme conjugate having one or more enzymes or biological catalysts, the enzymes or biological catalysts are modified with palmitic acid N-hydroxysuccinimide ester and acrylic acid N-hydroxysuccinimide ester, and (b) a thermally responsive polymer, wherein the functionalized enzyme conjugate is encapsulated within the thermally responsive polymer. A nanocatalyst is provided that has one or more proteins. The proteins are covalently immobilized and encapsulated within a thermally responsive polymer shell. The proteins are one or more enzymes or biological catalysts. A method for protecting the proteins is also set forth. |
| FILED | Thursday, November 11, 2010 |
| APPL NO | 12/944200 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/182 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460921 | Gross |
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| FUNDED BY |
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| APPLICANT(S) | Guenter W. Gross (Denton, Texas) |
| ASSIGNEE(S) | University of North Texas (Denton, Texas) |
| INVENTOR(S) | Guenter W. Gross (Denton, Texas) |
| ABSTRACT | A neuronal network analysis plate having alternating rows of recording wells and amplifying wells. The recording wells contain a neural cell network and a series of electrodes for recording the action potential signals of the neurons. The electrodes are connected to amplifiers in adjacent amplifying wells. The close proximity of these amplifiers ideal because it permits the parallel, non-multiplexed recording of action potential signals from multiple different active nerve cell networks. The amplifiers in the amplifying wells can then be connected to external amplification equipment. The neuronal network analysis plate may be contained within a single commercially available 24 or 96 well plate. The neuronal network analysis plate can be used to detect and quantify pharmacological and toxicological responses of the neural cells to one or more agents in vitro. |
| FILED | Wednesday, September 12, 2007 |
| APPL NO | 12/441703 |
| ART UNIT | 1775 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461118 | Yates et al. |
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| FUNDED BY |
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| APPLICANT(S) | Clayton Yates (Auburn, Alabama); Jesse Jaynes (Auburn, Alabama); Timothy Turner (Auburn, Alabama) |
| ASSIGNEE(S) | Tuskegee University (Tuskegge, Alabama) |
| INVENTOR(S) | Clayton Yates (Auburn, Alabama); Jesse Jaynes (Auburn, Alabama); Timothy Turner (Auburn, Alabama) |
| ABSTRACT | Lytic peptides, including fusion peptides of lytic peptides conjugated with luteinizing hormone-releasing hormone or modified versions thereof to target luteinizing hormone-releasing hormone receptors, are disclosed. The lytic peptides show anti-proliferative activity against human prostate cancer cell lines, but are nontoxic to normal primary human prostate epithelial cells or to bone marrow stromal cells in co-culture. The lytic peptides have specificity for and anti-proliferative activity against prostate cancer tumor cells, and low toxicity for normal prostate cells, making the peptides useful in therapies for prostate cancer. |
| FILED | Thursday, July 07, 2011 |
| APPL NO | 13/178042 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461119 | Pasquale et al. |
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| FUNDED BY |
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| APPLICANT(S) | Elena B. Pasquale (San Diego, California); Mitchell Koolpe (San Diego, California); Keith K. Murai (Candiac, Canada) |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Elena B. Pasquale (San Diego, California); Mitchell Koolpe (San Diego, California); Keith K. Murai (Candiac, Canada) |
| ABSTRACT | Novel agents are described that bind to Eph receptors. Methods of using these agents to modulate the activity of Eph receptors, stimulate apoptosis, and deliver therapeutic agents are also described. Methods of screening for agents capable of selectively binding to Eph receptors are also described. |
| FILED | Friday, August 29, 2003 |
| APPL NO | 10/652407 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461127 | Scadden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David T. Scadden (Weston, Massachusetts); Tao Cheng (Newton, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David T. Scadden (Weston, Massachusetts); Tao Cheng (Newton, Massachusetts) |
| ABSTRACT | The expansion of a population of stem cells or progenitor cells, or precursors thereof, may be accomplished by disrupting or inhibiting p21cip1/waf1 and/or p27, cyclin dependent kinase inhibitors. In the absence of p27 activity, progenitor cells move into the cell cycle and proliferate; whereas in the absence of p21 activity, stem cells move into the cell cycle and proliferate without losing their pluripotentiality (i.e., their ability to differentiate into the various cell lines found in the blood stream). Any type of stem cell or progenitor cell, or precursor thereof, including, but not limited to, hematopoietic, gastrointestinal, lung, neural, skin, muscle, cardiac muscle, renal, mesenchymal, embryonic, fetal, or liver cell may be used in accordance with the invention. The present invention provides a method of expanding a cell population, cells with decreased p27 and/or p21 activity, transgenic animals with a disrupted p27 and/or p21 gene, pharmaceutical compositions comprising the cells of the invention, and methods of using these cells in gene therapy (e.g., stem cell gene therapy) and bone marrow transplantation. |
| FILED | Tuesday, January 03, 2012 |
| APPL NO | 13/342819 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461223 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Je Kyun Lee (Brookline, Massachusetts); George L. Gould (Mendon, Massachusetts) |
| ASSIGNEE(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| INVENTOR(S) | Je Kyun Lee (Brookline, Massachusetts); George L. Gould (Mendon, Massachusetts) |
| ABSTRACT | Microporous polyolefin and microporous polydicyclopentadiene (polyDCPD) based aerogels and methods for preparing and using the same are provided. The aerogels are produced by forming a polymer gel structure within a solvent from a olefin or dicyclopentadiene monomer via Ring Opening Metathesis Polymerization (ROMP) reactions, followed by supercritical drying to remove the solvent from the aerogel. Other aerogels are prepared by sequentially (1) mixing at least one dicyclopentadiene monomer, at least one solvent at least one catalyst and at least one inorganic and/or organic reinforcing material, (2) gelling the mixture, (3) aging, and (4) supercritical drying. Aerogels provided herein are inexpensive to prepare, possess desirable thermal, mechanical, acoustic, chemical, and physical properties and are hydrophobic. The aerogels provided herein are suitable for use in various applications, including but not limited to thermal and acoustic insulation, radiation shielding, and vibrational damping applications. |
| FILED | Thursday, April 06, 2006 |
| APPL NO | 11/278940 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461362 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ching-Shih Chen (Upper Arlington, Ohio); Dasheng Wang (Dublin, Ohio); Samuel K. Kulp (Hilliard, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ching-Shih Chen (Upper Arlington, Ohio); Dasheng Wang (Dublin, Ohio); Samuel K. Kulp (Hilliard, Ohio) |
| ABSTRACT | Tocopheryl succinate derivatives according to formula I: are described. These compounds increase the activity of protein phosphatase 2A, can be included in pharmaceutical compositions, and can be used for the treatment of androgen receptor-dependent cancers such as prostate cancer. |
| FILED | Tuesday, April 13, 2010 |
| APPL NO | 12/758858 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/407 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461501 | Williams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Darin S. Williams (Tucson, Arizona); Nicholas B. Saccketti (Tucson, Arizona); David B. Hatfield (Oracle, Arizona); Alexandra L. Blake (Tucson, Arizona); Richard J. Wright (Tucson, Arizona); Lawrence A. Westhoven, Jr. (Tucson, Arizona) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Darin S. Williams (Tucson, Arizona); Nicholas B. Saccketti (Tucson, Arizona); David B. Hatfield (Oracle, Arizona); Alexandra L. Blake (Tucson, Arizona); Richard J. Wright (Tucson, Arizona); Lawrence A. Westhoven, Jr. (Tucson, Arizona) |
| ABSTRACT | Embodiments of a guided munition are provided, as are embodiments of a method for equipping a guided munition with a self-deploying dome cover. In one embodiment, the guided munition includes a munition body, a seeker dome coupled to the munition body, and a self-deploying dome cover disposed over the seeker dome. The self-deploying dome cover is configured to deploy and expose the seeker dome during munition flight in response to aerodynamic forces acting on the self-deploying dome cover. |
| FILED | Tuesday, November 02, 2010 |
| APPL NO | 12/917699 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/3.160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461532 | La Lumondiere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stephen La Lumondiere (Torrance, California); Terence Yeoh (Pasadena, California); Martin Siu Wo Leung (Redondo Beach, California); Neil A. Ives (Hawthrone, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Stephen La Lumondiere (Torrance, California); Terence Yeoh (Pasadena, California); Martin Siu Wo Leung (Redondo Beach, California); Neil A. Ives (Hawthrone, California) |
| ABSTRACT | An illumination source may be directed towards a surface of an object comprising subsurface features, wherein the illumination from the source is directed at a first angle relative to the normal of the surface. The object may have a portion between the subsurface features and the surface, the portion having an index of refraction that is greater than the index of refraction of a surrounding medium that surrounds the object. An imaging device may be placed with an objective lens. The first angle may be larger than an acceptance angle of the objective lens. In some embodiments, multiple illumination beams may be generated by one or more illumination sources. The beams may be rotated relative to one another about the normal of the surface. Also, in some embodiments, multiple images may be taken with the objective of the imaging device at different positions rotated off of the normal. The multiple images may be combined to generate a composite image. |
| FILED | Friday, March 26, 2010 |
| APPL NO | 12/661967 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/339.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461664 | Bennett et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brian R. Bennett (Arlington, Virginia); John Bradley Boos (Springfield, Virginia); Mario Ancona (Alexandria, Virginia); James G. Champlain (Alexandria, Virginia); Nicolas A Papanicolaou (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brian R. Bennett (Arlington, Virginia); John Bradley Boos (Springfield, Virginia); Mario Ancona (Alexandria, Virginia); James G. Champlain (Alexandria, Virginia); Nicolas A Papanicolaou (Potomac, Maryland) |
| ABSTRACT | A complementary metal oxide semiconductor (CMOS) device in which a single InxGa1-xSb quantum well serves as both an n-channel and a p-channel in the same device and a method for making the same. The InxGa1-xSb layer is part of a heterostructure that includes a Te-delta doped AlyGa1-ySb layer above the InxGa1-xSb layer on a portion of the structure. The portion of the structure without the Te-delta doped AlyGa1-ySb barrier layer can be fabricated into a p-FET by the use of appropriate source, gate, and drain terminals, and the portion of the structure retaining the Te-delta doped AlyGa1-ySb layer can be fabricated into an n-FET so that the structure forms a CMOS device, wherein the single InxGa1-xSb quantum well serves as the transport channel for both the n-FET portion and the p-FET portion of the heterostructure. |
| FILED | Wednesday, May 25, 2011 |
| APPL NO | 13/115453 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/615 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461703 | Dunn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul M. Dunn (West Kingston, Rhode Island); Christopher J. Egan (South Kingstown, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul M. Dunn (West Kingston, Rhode Island); Christopher J. Egan (South Kingstown, Rhode Island) |
| ABSTRACT | A engine-generator is provided which has a rotary engine formed with an engine housing having an output surface portion and an output shaft on a central axis extending externally of the engine housing. A generator has a stator secured to the output end of the shaft and has a surface in a confronting relation with the engine housing. Permanent magnets and windings are secured to the respective surface portion of the engine housing and stator at a radial distance from the axis. Each magnet and winding has a corresponding pole face lying in a corresponding one of a pair of first planes orthogonal to the central axis. The magnets and windings are rotatable with respect to each other and periodically align in a confronting relationship to define an air-gap between the parallel planes. The windings produce electrical output in response to rotation of the magnets relative to each other. |
| FILED | Friday, April 22, 2011 |
| APPL NO | 13/092297 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Prime-mover dynamo plants 290/1.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461762 | Rostoker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Norman Rostoker (Irvine, California); Michl Binderbauer (Irvine, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Norman Rostoker (Irvine, California); Michl Binderbauer (Irvine, California) |
| ABSTRACT | An apparatus and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy well, created by tuning an externally applied magnetic field. The simultaneous electrostatic confinement of electrons and magnetic confinement of ions avoids anomalous transport and facilitates classical containment of both electrons and ions. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions ions are fused together by nuclear force, thus releasing fusion energy. Moreover, the fusion fuel plasmas that can be used with the present confinement system and method are not limited to neutronic fuels only, but also advantageously include advanced fuels. |
| FILED | Wednesday, July 29, 2009 |
| APPL NO | 12/511266 |
| ART UNIT | 2821 — Electrical Circuits and Systems |
| CURRENT CPC | Electric lamp and discharge devices: Systems 315/111.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461851 | Iskander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Magdy F. Iskander (Honolulu, Hawaii); Hyoungsun Youn (Honolulu, Hawaii); Charles Amazeen (Arlington, Virginia); Brian Burns (Alexandria, Virginia) |
| ASSIGNEE(S) | University of Hawaii (Honolulu, Hawaii) |
| INVENTOR(S) | Magdy F. Iskander (Honolulu, Hawaii); Hyoungsun Youn (Honolulu, Hawaii); Charles Amazeen (Arlington, Virginia); Brian Burns (Alexandria, Virginia) |
| ABSTRACT | A slotted TEM transmission line and an in-situ TEM transmission line are utilized to determine both complex permittivity and permeability of soil. The permittivity and permeability information may be used by underground sensing techniques such as GPR and EMI to enhance information from these techniques. The in-situ probe provides that both complex permittivity and permeability can be measured simultaneously over a broad frequency range without disturbing the soil conditions. |
| FILED | Friday, April 09, 2010 |
| APPL NO | 12/757859 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/637 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461948 | Pulskamp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffrey S. Pulskamp (Leesburg, Virginia); Daniel C. Judy (Odenton, Maryland); Ronald G. Polcawich (Derwood, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey S. Pulskamp (Leesburg, Virginia); Daniel C. Judy (Odenton, Maryland); Ronald G. Polcawich (Derwood, Maryland) |
| ABSTRACT | An electrostatic ohmic shunt radio frequency (RF) microelectromechanical system (MEMS) switch and method of manufacturing includes a co-planar waveguide (CPW) transmission line comprising a plurality of slots and a plurality of pillars, wherein a space between successive ones of the plurality of pillars is defined by one of the plurality of slots; a plurality of electrodes positioned in the slots; a conductive contact beam elevated over the CPW transmission line and the plurality of electrodes; and a plurality of conductive contact dimples positioned between the conductive contact beam and the CPW transmission line, wherein the plurality of pillars are adapted to prevent physical contact between the plurality of electrodes and the conductive contact beam. |
| FILED | Tuesday, September 25, 2007 |
| APPL NO | 11/860765 |
| ART UNIT | 2832 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Magnetically operated switches, magnets, and electromagnets 335/78 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462078 | Murphey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas W. Murphey (Albuquerque, New Mexico); Jeremy A. Banik (Albuquerque, New Mexico); Whitney D. Reynolds (Albuquerque, New Mexico); Laura A. Stiles (Prairie Village, Kansas) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Thomas W. Murphey (Albuquerque, New Mexico); Jeremy A. Banik (Albuquerque, New Mexico); Whitney D. Reynolds (Albuquerque, New Mexico); Laura A. Stiles (Prairie Village, Kansas) |
| ABSTRACT | A reflector useful for communications, radar and sensing application in space and on earth includes thin shell gores emanating from a geometric center of the reflector at its hub. Gores are provided in a spiraled pattern and are in elastic connection to said hub and wrapped around their point of convergence at the hub when the reflector is stowed. The gores emanate from the geometric center of the reflector hub at their elastic connection to the hub when they are deployed and operational as a reflector with a point of convergence to promote operation as a reflector. Thin shell gores can have an inner perimeter and outer perimeter, can be provided in a spiraled pattern, and can be interlocked at their outer perimeter, or in-between their inner and outer perimeter, while also remaining in elastic connection at their inner perimeter to said hub. |
| FILED | Tuesday, December 14, 2010 |
| APPL NO | 12/967814 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/915 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462179 | Fleet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Erin F. Fleet (Springfield, Virginia); Andrey V. Kanaev (Lorton, Virginia); Dean A Scribner (Arlington, Virginia); John R. Ackerman (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Erin F. Fleet (Springfield, Virginia); Andrey V. Kanaev (Lorton, Virginia); Dean A Scribner (Arlington, Virginia); John R. Ackerman (Alexandria, Virginia) |
| ABSTRACT | A method and system is provided for performing high-resolution image assembly regardless of observed scene content. An imaging system, including a focal plane array and lenslet array can be calibrated to account for subimage shifts. A calibration module can determine the subimage shifts by calculating an average point source position reference point coordinates for each of the subimages, and then determining the difference between the average point source position and the reference point coordinates for each subimage. The imaging system can then be calibrated utilizing the subimage shifts for each of the plurality of subimages. Finally, an assembly module can perform a high-resolution image assembly with the calibrated imaging system. |
| FILED | Monday, July 20, 2009 |
| APPL NO | 12/505851 |
| ART UNIT | 2679 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/629 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462323 | Markov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vladimir B. Markov (Irvine, California); Anatoliy I. Khizhnyak (Irvine, California) |
| ASSIGNEE(S) | MetroLaser, Inc. (Laguna Hills, California) |
| INVENTOR(S) | Vladimir B. Markov (Irvine, California); Anatoliy I. Khizhnyak (Irvine, California) |
| ABSTRACT | A sensor system for remote object detection, tracking, characterization, and discrimination can have a plurality of sensors. A shared optical train that can facilitate blending of information from the sensors, so as to provide a single view for the plurality of sensors. Small and/or dim objects can be more readily detected. High-resolution 3 dimensional space object imagery and on-demand target information gathering can be provided with reduced data latency. The undesirable effects of atmospheric turbulence along the aiming direction can be mitigated even when there is a high relative velocity between the surveillance platform and remote target. |
| FILED | Thursday, March 27, 2008 |
| APPL NO | 12/057254 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/73 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462333 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wei Wu (Palo Alto, California); Zhiyong Li (Redwood City, California); Shih-Yuan Wang (Palo Alto, California); Michael Josef Stuke (Palo Alto, California); Lars Helge Thylen (Huddinge, Sweden); Fung Suong Ou (Palo Alto, California); Min Hu (Sunnyvale, California) |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Wei Wu (Palo Alto, California); Zhiyong Li (Redwood City, California); Shih-Yuan Wang (Palo Alto, California); Michael Josef Stuke (Palo Alto, California); Lars Helge Thylen (Huddinge, Sweden); Fung Suong Ou (Palo Alto, California); Min Hu (Sunnyvale, California) |
| ABSTRACT | An apparatus for performing SERS includes a substrate and flexible nano-fingers, each of the nano-fingers having a first end attached to the substrate, a free second end, and a body portion extending between the first end and the second end, in which the nano-fingers are arranged in an array on the substrate. The apparatus also includes an active material layer disposed on each of the second ends of the plurality of nano-fingers, in which the nano-fingers are to be in a substantially collapsed state in which the active layers on at least two of the nano-fingers contact each other under dominant attractive forces between the plurality of nano-fingers and in which the active material layers are to repel each other when the active material layers are electrostatically charged. |
| FILED | Friday, October 15, 2010 |
| APPL NO | 12/905891 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462426 | Dajani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iyad A. Dajani (Albuquerque, New Mexico); Clint M. Zeringue (Albuquerque, New Mexico) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Iyad A. Dajani (Albuquerque, New Mexico); Clint M. Zeringue (Albuquerque, New Mexico) |
| ABSTRACT | A method to increase the output power of monolithic narrow-linewidth Yb-doped fiber amplifiers by suppressing simulated Brillouin scattering. The fiber amplifier employs a co-propagating geometry and is seeded with broad- (source 2) and narrow- (source 1) linewidth signals that are sufficiently different in wavelengths to allow for efficient gain competition and favorable temperature profile at the output end of fiber. The broadband seed signal possesses the higher emission and absorption cross sections. If source 2 is also given sufficiently greater input power than source 1, it will be amplified to its maximum value as the seed signals reach the middle portion of the gain fiber. Beyond that portion, the signal having the lower emission and absorption cross sections (signal 1) will continue to experience gain by power transfer from both signal 2 and the pump light, attaining a power output well beyond what the maximum output would have been had the amplifier been illuminated with a single frequency beam. Furthermore, if the two signals are carefully selected such that appreciable quantum defect heating occurs during the power transfer, a steep thermal gradient develops leading to even further increase in output power. |
| FILED | Thursday, December 03, 2009 |
| APPL NO | 12/630217 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/334 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462565 | Venugopal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sameer M. Venugopal (San Jose, California); David R. Allee (Phoenix, Arizona); Lawrence T. Clark (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Sameer M. Venugopal (San Jose, California); David R. Allee (Phoenix, Arizona); Lawrence T. Clark (Phoenix, Arizona) |
| ABSTRACT | Embodiments and examples of differential threshold voltage non-volatile memories and related methods are described herein. In one example, a method for providing an integrated circuit can comprise providing a memory cell coupled to a first bitline and to a second bitline, and at least one of (a) providing a read assist mechanism configured to couple to the memory cell via the first and second bitlines, or (b) providing a memory reset mechanism configured to couple to the memory cell via the first and second bitlines. Providing the memory cell can comprise providing a first transistor comprising a first threshold voltage, providing a second transistor comprising a second threshold voltage, and cross-coupling the first and second transistors of the memory cell together. A difference between the first and second threshold voltages can correspond to a logic state of the memory cell. Other embodiments, examples, and related methods are also disclosed herein. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/083427 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/189.150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462681 | Pochiraju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kishore Pochiraju (Princeton Junction, New Jersey); Biruk Gebre (Weehawken, New Jersey); Hao Men (Harrison, New Jersey) |
| ASSIGNEE(S) | The Trustees of Stevens Institute of Technology (Hoboken, New Jersey) |
| INVENTOR(S) | Kishore Pochiraju (Princeton Junction, New Jersey); Biruk Gebre (Weehawken, New Jersey); Hao Men (Harrison, New Jersey) |
| ABSTRACT | Disclosed is a method and apparatus to continuously transmit high bandwidth, real-time data, on a communications network (e.g., wired, wireless, and a combination of wired and wireless segments). A control computing device uses user or application requirements to dynamically adjust the throughput of the system to match the bandwidth of the communications network being used, so that data latency is minimized. An operator can visualize the instantaneous characteristic of the link and, if necessary, make a tradeoff between the latency and resolution of the data to help maintain the real-time nature of the system and better utilize the available network resources. Automated control strategies have also been implemented into the system to enable dynamic adjustments of the system throughput to minimize latency while maximizing data resolution. Several applications have been cited in which latency minimization techniques can be employed for enhanced dynamic performance. |
| FILED | Wednesday, January 13, 2010 |
| APPL NO | 12/686860 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462828 | Estes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lee E. Estes (Mattapoisett, Massachusetts) |
| ASSIGNEE(S) | The United States of Americas as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee E. Estes (Mattapoisett, Massachusetts) |
| ABSTRACT | A system is provided to generate coherent single-frequency and single transverse mode light pulses. A laser produces a linearly-polarized continuous wave beam defined by a single longitudinal and transverse mode. A first rotator processes the beam such that optical polarization is rotated during a first time period and not rotated during a second and third time period. A second rotator is operated during the first period to rotate optical polarization of the beam, during the second period to not rotate the beam, and during the third period to rotate the beam. An optical loop amplifies the beam during the first and second periods. An amplifier device can be added to the loop for amplification. A first beam splitter allows the beam to enter the loop and a second splitter directs the beam along the loop during the first and second periods and out of the loop during the third period. |
| FILED | Friday, March 04, 2011 |
| APPL NO | 13/040995 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/106 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462879 | Dybdal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert B. Dybdal (Palos Verdes, California); Samuel J. Curry (Redondo Beach, California); Flavio Lorenzelli (Los Angeles, California); Don J. Hinshilwood (Torrance, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Robert B. Dybdal (Palos Verdes, California); Samuel J. Curry (Redondo Beach, California); Flavio Lorenzelli (Los Angeles, California); Don J. Hinshilwood (Torrance, California) |
| ABSTRACT | Systems and methods for increasing communications bandwidth using non-orthogonal polarizations are provided herein. Under one aspect, a method of transmitting M independent signals, where M is at least 3, includes receiving the M signals from respective sources; at a transmitter polarization module, obtaining first and second linear combinations of the M signals; providing the first and second linear combinations to first and second input ports of a transmitter antenna; and transmitting with the transmitter antenna the first linear combination at a first polarization and the second linear combination at a second polarization orthogonal to the first polarization. The method may further include receiving at a receiver antenna the first linear combination at the first polarization, and the second linear combination at the second polarization; obtaining at receiver circuitry the M signals based on the received first and second linear combinations; and outputting the M signals on respective output ports. |
| FILED | Thursday, February 02, 2012 |
| APPL NO | 13/364638 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463053 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zhen Guo (Elkins Park, Pennsylvania); Zhongfei (Mark) Zhang (Vestal, New York) |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Binghamton, New York) |
| INVENTOR(S) | Zhen Guo (Elkins Park, Pennsylvania); Zhongfei (Mark) Zhang (Vestal, New York) |
| ABSTRACT | Multimodal data mining in a multimedia database is addressed as a structured prediction problem, wherein mapping from input to the structured and interdependent output variables is learned. A system and method for multimodal data mining is provided, comprising defining a multimodal data set comprising image information; representing image information of a data object as a set of feature vectors in a feature space; clustering in the feature space to group similar features; associating a non-image representation with a respective image data object based on the clustering; determining a joint feature representation of a respective data object as a mathematical weighted combination of a set of components of the joint feature representation; optimizing a weighting for a plurality of components of the mathematical weighted combination with respect to a prediction error between a predicted classification and a training classification; and employing the mathematical weighted combination for automatically classifying a new data object. |
| FILED | Monday, August 10, 2009 |
| APPL NO | 12/538845 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/225 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463582 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dong Song (Irvine, California); Vasilis Z. Marmarelis (Rancho Palos Verdes, California); Theodore W. Berger (Rancho Palos Verdes, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Dong Song (Irvine, California); Vasilis Z. Marmarelis (Rancho Palos Verdes, California); Theodore W. Berger (Rancho Palos Verdes, California) |
| ABSTRACT | Systems and techniques, including machine-readable instructions, for modeling of nonlinear systems. In one aspect, an apparatus includes a collection of two or more inputs configured and arranged to receive input signals, a collection of two or more outputs configured and arranged to output output signals, a processing unit configured to transform the input signals into the output signals, wherein the transformation is non-linear and treats the non-linear system as a collection of multiple input, single output non-linear systems, and a data storage that stores characteristics of the transformation. |
| FILED | Monday, June 09, 2008 |
| APPL NO | 12/135904 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463610 | Bourke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Patrick J. Bourke (Pittsburgh, Pennsylvania); Rob A. Rutenbar (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick J. Bourke (Pittsburgh, Pennsylvania); Rob A. Rutenbar (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to a low-power speech recognition system. In one embodiment, the speech recognition system is implemented in hardware and includes a backend search engine that operates to recognize words based on senone scores provided by an acoustic scoring stage. The backend search engine includes a scoring engine, a transition engine, and a language model engine. For a frame of sampled speech, the scoring engine reads active acoustic unit models from external memory, updates the active acoustic unit models based on corresponding senone scores received from an acoustic scoring stage, and writes the active acoustic unit models back to the external memory. The scoring engine enters a low-power state until processing for a next frame of sampled speech is to begin. The transition stage identifies any completed words, and the language model engine processes completed words to identify words that are likely to follow in a subsequent frame. |
| FILED | Monday, January 19, 2009 |
| APPL NO | 12/355973 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/257 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463723 | Modha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dharmendra S. Modha (San Jose, California); Chandrasekhar Narayan (San Jose, California); John C. Scott (Los Gatos, California) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dharmendra S. Modha (San Jose, California); Chandrasekhar Narayan (San Jose, California); John C. Scott (Los Gatos, California) |
| ABSTRACT | An electronic synapse device is provided. One embodiment of the invention includes a metastable switching synaptic device. Changing conductance of the metastable switching synaptic device occurs by receiving opposite signed first and second voltage pulses at the metastable switching synaptic device where magnitude of the first voltage pulse and the second voltage pulse each are below a switching voltage magnitude threshold. A magnitude difference between the first voltage pulse and the second voltage pulse exceeds the switching voltage magnitude threshold by an amount, wherein the amount is a function of a relative timing between the first voltage pulse and the second voltage pulse. |
| FILED | Sunday, March 01, 2009 |
| APPL NO | 12/395693 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464002 | Burger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Doug Burger (Redmond, Washington); Haiming Liu (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Doug Burger (Redmond, Washington); Haiming Liu (Austin, Texas) |
| ABSTRACT | The present disclosure generally relates to cache memory systems and/or techniques to identify dead cache blocks in cache memory systems. Example systems may include a cache memory that is accessible by a cache client. The cache memory may include a plurality of storage locations for a first cache block, with a most recently used position location in the cache memory. A cache controller may be configured to predict whether the first cache block stored in the cache memory is identified as a dead cache block based on a cache burst of the first cache block. The cache burst may comprise a first access of the first cache block by a cache client and any subsequent contiguous accesses of the first cache block following the first access by the cache client while the first cache block is in a most recently used position of the cache set. |
| FILED | Wednesday, October 14, 2009 |
| APPL NO | 12/579183 |
| ART UNIT | 2188 — AI & Simulation/Modeling |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464191 | McIlrath |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lisa G. McIlrath (Lexington, Massachusetts) |
| ASSIGNEE(S) | R3 Logic, Inc. (Bedford, Massachusetts) |
| INVENTOR(S) | Lisa G. McIlrath (Lexington, Massachusetts) |
| ABSTRACT | A system and method for identifying circuit components of an integrated circuit includes a processor identifying geometric characteristics of an integrated circuit and sorting the geometric characteristics by order of occurrence of each geometric characteristic. Co-occurring arrangements of the geometric characteristics are then identified and used to identify a standard cell. The geometric characteristics of the standard cell may then be compared to the geometric characteristics of a known cell. Each electrically significant geometric characteristic of the standard cell can be compared to the electrically significant geometric characteristics of the known cell. If the standard cell matches the known cell an instance of the standard cell can be placed in a layout. Once placing the standard cell in the layout a netlist can be extracted. |
| FILED | Thursday, July 21, 2011 |
| APPL NO | 13/187912 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/107 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE44288 | Kimball et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ronald L. Kimball (Corning, New York); Robert A. Knowlton (Wellsboro, Pennsylvania); Joseph E. McCarthy (Addison, New York); Ji Wang (Painted Post, New York); Donnell T. Walton (Painted Post, New York); Luis A. Zenteno (Painted Post, New York) |
| ASSIGNEE(S) | Corning Incorporated (Corning, New York) |
| INVENTOR(S) | Ronald L. Kimball (Corning, New York); Robert A. Knowlton (Wellsboro, Pennsylvania); Joseph E. McCarthy (Addison, New York); Ji Wang (Painted Post, New York); Donnell T. Walton (Painted Post, New York); Luis A. Zenteno (Painted Post, New York) |
| ABSTRACT | According to one example of the invention an optical fiber comprises: (i) silica based, rare earth doped core having a first index of refraction n1; (ii) at least one silica based cladding surrounding the core and having a second index of refraction n2, such that n1>n2; wherein at least one of the core or cladding is doped with Al2O3, such that the ratio of max wt % to min wt % of Al2O3 concentration is less than 2:1. |
| FILED | Wednesday, July 29, 2009 |
| APPL NO | 12/511311 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/142 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 08459098 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Larry Alan Lee (Westover, West Virginia); Michael Martin Flemmer (Bruceton Mills, West Virginia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Larry Alan Lee (Westover, West Virginia); Michael Martin Flemmer (Bruceton Mills, West Virginia) |
| ABSTRACT | The present invention discloses a physiologic sampling pump (PSP) which uses at least one valve placed near the sampling medium to modulate air sampling to follow a person's inhalation rate and to obviate the sluggishness inherent in prior art PSPs caused by varying pump speed and by the propagation time through an air tube that connects the collection medium to prior art pumps thereby also obviating limitations inherent in system response, functionality, and accuracy. Moreover, by maintaining an essentially constant air flow through a cyclone at all times and through the collection medium while sampling, the present invention operates at known collection efficiencies, and is therefore capable of size-selective sampling of particulates as opposed to prior art PSPs that by varying the magnitude of air flow, make the separation efficiencies of pre-collection devices indeterminate and the samples worthless. When used instead with an impact sampling head, the present invention may collect total particulate as well, and may collect gases and vapors with a charcoal tube sampling head. Structural features associated with the physiological sampling pump for providing rapid response to breathing include an outer housing including a thereto-resistant case, multiple and interchangeable PSP sampling heads further including collection media and a valve(s) mounted on a valve manifold with associated tubing. |
| FILED | Wednesday, January 20, 2010 |
| APPL NO | 12/690550 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/31.70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459295 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chang-Jin Kim (Beverly Hills, California); Wyatt C. Nelson (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chang-Jin Kim (Beverly Hills, California); Wyatt C. Nelson (Los Angeles, California) |
| ABSTRACT | A microfluidic device for droplet manipulation includes a substrate, a plurality of electrically addressable thin-film electrodes disposed on the substrate, at least one of the plurality of electrodes comprising a heating element in the form of a patterned electrode. A hydrophilic region is disposed in or above a portion of the heating element. The hydrophilic region may be permanent or electronically actuable. The thin-film electrodes have multi-function capabilities including, for instance, heating, temperature sensing, and/or sample actuation. |
| FILED | Tuesday, January 19, 2010 |
| APPL NO | 13/144462 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Fluid handling 137/341 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459572 | Hering et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Susanne Hering (Berkeley, California); Gregory Lewis (Berkeley, California); Steven R. Spielman (Oakland, California) |
| ASSIGNEE(S) | Aerosol Dynamics Inc. (Berkeley, California) |
| INVENTOR(S) | Susanne Hering (Berkeley, California); Gregory Lewis (Berkeley, California); Steven R. Spielman (Oakland, California) |
| ABSTRACT | Technology is presented for the high efficiency concentration of fine and ultrafine airborne particles into a small fraction of the sampled airflow by condensational enlargement, aerodynamic focusing and flow separation. A nozzle concentrator structure including an acceleration nozzle with a flow extraction structure may be coupled to a containment vessel. The containment vessel may include a water condensation growth tube to facilitate the concentration of ultrafine particles. The containment vessel may further include a separate carrier flow introduced at the center of the sampled flow, upstream of the acceleration nozzle of the nozzle concentrator to facilitate the separation of particle and vapor constituents. |
| FILED | Friday, October 22, 2010 |
| APPL NO | 12/910705 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460316 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fletcher T. Wilson (San Francisco, California); Rhunjay J. Yu (Mountain View, California) |
| ASSIGNEE(S) | The Board of Trustees of The Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Fletcher T. Wilson (San Francisco, California); Rhunjay J. Yu (Mountain View, California) |
| ABSTRACT | A method of manipulating tissue at a vessel includes advancing a device distally relative to an opening at an interior surface of the vessel, and into a first wall portion of a vessel until an entirety of the device is within the wall of the vessel, the device having a distal end, a proximal end, and a cutting element coupled to the proximal end, and using the cutting element to increase a size of the opening by retracting the device proximally. |
| FILED | Friday, February 25, 2011 |
| APPL NO | 13/035818 |
| ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 66/139 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460528 | Pollack et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael G. Pollack (Durham, North Carolina); Alexander Shenderov (Raleigh, North Carolina); Philip Paik (Chula Vista, California); Vijay Srinivasan (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina) |
| ASSIGNEE(S) | Advanced Liquid Logic Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Michael G. Pollack (Durham, North Carolina); Alexander Shenderov (Raleigh, North Carolina); Philip Paik (Chula Vista, California); Vijay Srinivasan (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina) |
| ABSTRACT | On-board reagent storage, handling, and dispensing apparatuses and methods for droplet actuator systems are provided. In one embodiment, a fluidic analyzer is provided and includes a droplet actuator including a substrate including a plurality of electrodes configured to actuate a droplet and a reagent storage component in selective fluid communication with the droplet actuator and including a reagent configured to combine with a solvent at a time of use. In another embodiment, a method of conducting fluidic analysis is provided and includes storing a reagent within a reagent storage component in fluid communication with a droplet actuator including a plurality of electrodes configured to actuate a droplet and combining the reagent with a solvent at a time for use within the droplet actuator. |
| FILED | Tuesday, October 14, 2008 |
| APPL NO | 12/681879 |
| ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460642 | Ellies et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Debra Ellies (Parkville, Missouri); William Rosenberg (Overland Park, Missouri) |
| ASSIGNEE(S) | OssiFi, Inc. (Kansas City, Kansas) |
| INVENTOR(S) | Debra Ellies (Parkville, Missouri); William Rosenberg (Overland Park, Missouri) |
| ABSTRACT | The present invention provides a method of promoting bone growth in a subject in need thereof, by administering to the subject a therapeutically effective amount of a compound of Formula I. The present invention also provides methods for the treatment of renal disease and cancer. |
| FILED | Wednesday, April 25, 2012 |
| APPL NO | 13/456060 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460646 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Riyi Shi (West Lafayette, Indiana); Richard B. Borgens (Delphi, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Riyi Shi (West Lafayette, Indiana); Richard B. Borgens (Delphi, Indiana) |
| ABSTRACT | To achieve, an in vivo repair of injured mammalian nerve tissue, an effective amount of a biomembrane fusion agent is administered to the injured nerve tissue. The application of the biomembrane fusion agent may be performed by directly contacting the agent with the nerve tissue at the site of the injury. Alternatively, the biomembrane fusion agent is delivered to the site of the injury through the blood supply after administration of the biomembrane fusion agent to the patient. The administration is preferably by parenteral administration including intravascular, intramuscular, subcutaneous, or intraperitoneal injection of an effective quantity of the biomembrane fusion agent so that an effective amount is delivered to the site of the nerve tissue injury. |
| FILED | Thursday, July 23, 2009 |
| APPL NO | 12/508184 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460651 | Marsala et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Martin Marsala (San Diego, California); Osamu Kakinohana (San Diego, California); Thomas G. Hazel (North Potomac, Maryland); Karl K. Johe (Potomac, Maryland) |
| ASSIGNEE(S) | Neuralstem, Inc. (Rockville, Maryland); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Martin Marsala (San Diego, California); Osamu Kakinohana (San Diego, California); Thomas G. Hazel (North Potomac, Maryland); Karl K. Johe (Potomac, Maryland) |
| ABSTRACT | The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord. |
| FILED | Monday, March 16, 2009 |
| APPL NO | 12/404841 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460660 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mitchell Ho (North Potomac, Maryland); Ira Pastan (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Mitchell Ho (North Potomac, Maryland); Ira Pastan (Potomac, Maryland) |
| ABSTRACT | The present invention provides monoclonal anti-mesothelin antibodies and antibody fragments and methods for their use. The antibodies can be completely human. |
| FILED | Tuesday, March 23, 2010 |
| APPL NO | 13/259138 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460674 | Koelle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David M. Koelle (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | David M. Koelle (Seattle, Washington) |
| ABSTRACT | The invention provides HSV antigens and epitopes that are useful for the prevention and treatment of HSV infection. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection. |
| FILED | Monday, February 08, 2010 |
| APPL NO | 12/702218 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/186.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460684 | Raines et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ronald T. Raines (Madison, Wisconsin); Bryan D. Smith (Madison, Wisconsin); Matthew B. Soellner (Madison, Wisconsin); David M. Lynn (Middleton, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); Bryan D. Smith (Madison, Wisconsin); Matthew B. Soellner (Madison, Wisconsin); David M. Lynn (Middleton, Wisconsin) |
| ABSTRACT | A class of anionic oligomers and polymers that function for inhibition of nucleases, particularly RNase. Specific inhibitors include mixtures of oligomers of vinyl sulfate. Methods for inhibition or inactivation of one or more nucleases in vitro which comprises the step of contacting the one or more nucleases in a biological medium with one or more of the anionic oligomeric or polymeric inhibitors of this invention. Kits for carrying out a biological procedure, biological reaction and/or a biological assay containing one or more inhibitors of this invention. The use of oligomers and/or polymers of this invention as additives in buffers or reagents. The inhibitors of the invention can also be attached to surfaces to provide for removal of nucleases from media, solutions or other liquids in contact with the solid. |
| FILED | Friday, March 18, 2005 |
| APPL NO | 11/084068 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460714 | Tseng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Wei Li (Guangdong, China PRC) |
| ASSIGNEE(S) | TissueTech, Inc. (Miami, Florida) |
| INVENTOR(S) | Scheffer Tseng (Pinecrest, Florida); Hua He (Miami, Florida); Wei Li (Guangdong, China PRC) |
| ABSTRACT | Compositions having a combination of specific biological components have been found to exert a number of useful effects in mammalian cells, including modulating TGF β signaling, apoptosis, and proliferation of mammalian cells, as well as decreasing inflammation in mice. These components can be obtained commercially, or can be prepared from biological tissues such as placental tissues. Placental amniotic membrane (AM) preparations described herein include AM pieces, AM extracts, AM jelly, AM stroma, and mixtures of these compositions with additional components. The compositions can be used to treat various diseases, such as wound healing, inflammation and angiogenesis-related diseases. |
| FILED | Tuesday, April 03, 2012 |
| APPL NO | 13/438759 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/583 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460744 | Bonner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert F. Bonner (Washington, District of Columbia); Thomas J. Pohida (Monrovia, Maryland); Michael R. Emmert-Buck (Easton, Maryland); Michael Anthony Tangrea (Odenton, Maryland); Rodrigo F. Chuaqui (North Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Robert F. Bonner (Washington, District of Columbia); Thomas J. Pohida (Monrovia, Maryland); Michael R. Emmert-Buck (Easton, Maryland); Michael Anthony Tangrea (Odenton, Maryland); Rodrigo F. Chuaqui (North Potomac, Maryland) |
| ABSTRACT | A device for performing target activated transfer that includes a mounting surface for mounting a tissue sample; and a light source positioned to substantially uniformly irradiate both stained and unstained regions of the tissue sample with light energy that activates the reagent to selectively adhere the stained regions to a transfer surface. Also described is an automated system for transferring tissue from a tissue sample to a transfer substrate. The system includes means for holding a tissue section that includes targets specifically stained with an absorptive stain thereby resulting in a stained tissue surface, and a flexible transfer film that includes a lower thermoplastic layer in sufficient thermal contact with the stained tissue surface; an irradiating assembly configured to provide a predetermined uniform light dose to the entire tissue section; and means for applying a constant pressure to the transfer film during irradiation. |
| FILED | Thursday, February 25, 2010 |
| APPL NO | 12/713105 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Coating processes 427/2.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460859 | Espina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia A. Espina (Rockville, Maryland); Lance A. Liotta (Bethesda, Maryland); David Geho (Oakton, Virginia) |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Virginia A. Espina (Rockville, Maryland); Lance A. Liotta (Bethesda, Maryland); David Geho (Oakton, Virginia) |
| ABSTRACT | This invention relates, e.g., to a composition that, at room temperature, when contacted with a sample comprising phosphoproteins, can fix and stabilize cellular phosphoproteins, preserve cellular morphology, and allow the sample to be frozen to generate a cryostat frozen section suitable for molecular analysis. The composition comprises (1) a fixative that is effective to fix the phosphoproteins, and that has a sufficient water content to be soluble for a stabilizer and/or a permeability enhancing agent); (2) a stabilizer, comprising (a) a kinase inhibitor and (b) a phosphatase inhibitor and, optionally, (c) a protease (e.g., proteinase) inhibitor; and (3) a permeability enhancing agent (e.g. PEG). Methods are described for preserving phosphoproteins, using such a composition. Also described are endogenous surrogate markers for monitoring protein degradation, including the loss of posttranslational modifications (such as phosphorylation), e.g. the following removal of a cell or tissue from a subject; and exogenous molecular sentinels (e.g. phosphoproteins attached to magnetic nanoparticles) that allow one to evaluate the processing history of a cellular or tissue population sample. |
| FILED | Friday, October 26, 2007 |
| APPL NO | 12/447773 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460862 | Coleman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Daniel J. Coleman (Corvallis, Oregon); John J. Naleway (Eugene, Oregon) |
| ASSIGNEE(S) | Marker Gene Technologies (Eugene, Oregon) |
| INVENTOR(S) | Daniel J. Coleman (Corvallis, Oregon); John J. Naleway (Eugene, Oregon) |
| ABSTRACT | The present invention relates to the visualization of acidic organelles based upon organelle enzyme activity. The organelle substrates of the invention are specific for enzyme activity of the organelle and label these organelles, such as lysosomes, rendering them visible and easily observed. Substrates of the present invention include substrates that produce a fluorescent signal. The fluorogenic acidic organelle enzyme substrates of this invention are designed to provide high fluorescence at low pH values and are derivatized to permit membrane permeation through both outer and organelle membranes of intact cells and can be used for staining cells at very low concentrations. They can be used for monitoring enzyme activity in cells at very low concentrations and are not toxic to living cells or tissues. |
| FILED | Wednesday, March 11, 2009 |
| APPL NO | 12/381560 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460868 | Brennan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark David Brennan (Jeffersonville, Indiana) |
| ASSIGNEE(S) | SureGene LLC (Louisville, Kentucky) |
| INVENTOR(S) | Mark David Brennan (Jeffersonville, Indiana) |
| ABSTRACT | The invention provides haplotypes and SNPs of the HPCAL1 and SV2C genes which predict the risk for developing schizophrenia or bipolar disorder and predict which patients are likely to respond to a given treatment or are more likely to experience negative side effects. |
| FILED | Monday, December 22, 2008 |
| APPL NO | 12/523243 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460889 | Heinecke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jay W. Heinecke (Seattle, Washington); Tomas Vaisar (Bellevue, Washington); Bryan Prazen (Seattle, Washington); Erik Nilsson (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); Insilicos, LLC (Seattle, Washington) |
| INVENTOR(S) | Jay W. Heinecke (Seattle, Washington); Tomas Vaisar (Bellevue, Washington); Bryan Prazen (Seattle, Washington); Erik Nilsson (Seattle, Washington) |
| ABSTRACT | The invention provides methods of screening a mammalian subject to determine if the subject is at risk to develop or is suffering from, cardiovascular disease. In one embodiment, the method comprises detecting a measurable feature of at least two biomarkers in an HDL subfraction, or in a complex containing apoA-I or apoA-III isolated from a biological sample obtained from the subject, wherein the at least two biomarkers are selected from the group consisting of apoA-I, apoA-II, apoB-100, Lp(a), apoC-I, and apoC-III, combinations or portions and/or derivatives thereof, and comparing the measurable features of the at least two biomarkers from the biological sample to a reference standard, wherein a difference in the measurable features of the at least two biomarkers from the biological sample and the reference standard is indicative of the presence or risk of cardiovascular disease in the subject. |
| FILED | Friday, July 06, 2012 |
| APPL NO | 13/543745 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460913 | Kamrud et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kurt I. Kamrud (Apex, North Carolina); Jonathan F. Smith (Cary, North Carolina); Maureen Maughan (Durham, North Carolina) |
| ASSIGNEE(S) | Alpha Vax, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Kurt I. Kamrud (Apex, North Carolina); Jonathan F. Smith (Cary, North Carolina); Maureen Maughan (Durham, North Carolina) |
| ABSTRACT | The present invention provides an isolated RNA molecule comprising: a) an alphavirus 5′ replication recognition sequence, wherein at least one initiation codon has been removed from the 5′ replication recognition sequence; b) a nucleotide sequence encoding an alphavirus structural protein; and c) an alphavirus 3′ replication recognition sequence, with the proviso that the RNA molecule does not contain a promoter that directs transcription of the nucleotide sequence of (b), and wherein the alphavirus 5′ and 3′ replication recognition sequences of (a) and (c) direct replication of the RNA molecule in the presence of alphavirus non-structural proteins. |
| FILED | Friday, June 20, 2008 |
| APPL NO | 12/665497 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460919 | Selitrennikoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Claude P. Selitrennikoff (Highlands Ranch, Colorado); Tamara K. Miller (Wheatridge, Colorado) |
| ASSIGNEE(S) | GlobeImmune, Inc. (Louisville, Colorado) |
| INVENTOR(S) | Claude P. Selitrennikoff (Highlands Ranch, Colorado); Tamara K. Miller (Wheatridge, Colorado) |
| ABSTRACT | Embodiments of the present invention illustrate methods of treating and preventing infection due to a pathogen such as a fungal pathogen. In particular, the present invention relates to compositions and methods for vaccinations against or treatment for a fungal organism in a non-immunocompromised or immunocompromised subject. |
| FILED | Wednesday, September 30, 2009 |
| APPL NO | 12/570947 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/255.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460924 | Zechiedrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | E. Lynn Zechiedrich (Houston, Texas); Jonathan Fogg (Houston, Texas); Daniel James Catanese, Jr. (Houston, Texas); Erol Bakkalbasi (Houston, Texas); Brian E. Gilbert (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | E. Lynn Zechiedrich (Houston, Texas); Jonathan Fogg (Houston, Texas); Daniel James Catanese, Jr. (Houston, Texas); Erol Bakkalbasi (Houston, Texas); Brian E. Gilbert (Houston, Texas) |
| ABSTRACT | The present invention relates to nucleic acid molecule compositions comprising MiniVectors™ encoding a nucleic acid sequence and methods of gene therapy using MiniVectors encoding a nucleic acid sequence. |
| FILED | Friday, October 15, 2010 |
| APPL NO | 12/905612 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460927 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lieping Chen (Hamden, Connecticut) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, None) |
| INVENTOR(S) | Lieping Chen (Hamden, Connecticut) |
| ABSTRACT | The invention provides novel polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid molecules, and cells containing the vectors. Also included are methods of making and using these co-stimulatory polypeptides. |
| FILED | Tuesday, October 25, 2011 |
| APPL NO | 13/280779 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460932 | Lowenstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pedro Lowenstein (Los Angeles, California); Maria Castro (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Pedro Lowenstein (Los Angeles, California); Maria Castro (Los Angeles, California) |
| ABSTRACT | The present invention relates to a method of prolonging the expression of an exogenous gene in a cell transduced with the exogenous gene. The method comprises co-administration of the exogenous gene with a herpes virus gene, whereby such co-administration prolongs the expression of the exogenous gene in the transduced cell. The method is particularly useful as a means of effecting gene therapy. |
| FILED | Wednesday, May 31, 2006 |
| APPL NO | 11/444050 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461103 | Anguita |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Juan Anguita (Florence, Massachusetts) |
| ASSIGNEE(S) | The University of North Carolina at Charlotte (Charlotte, North Carolina) |
| INVENTOR(S) | Juan Anguita (Florence, Massachusetts) |
| ABSTRACT | Salp15, biologically functional equivalents and fragments thereof, and nucleic acid molecules encoding the same are disclosed. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed. Salp15 gene products and Salp15 polypeptide fragments have biological activity in modulating CD4+ T cell activation through specific binding to CD4. Thus, therapeutic methods involving modulating T cell activation using Salp15 and biologically active polypeptide fragments thereof are also disclosed. The specific binding of Salp15 and fragment peptides thereof to CD4 can inhibit HIV infection of T cells, and thus methods of using Salp15 for inhibiting HIV infection are also disclosed. Screening methods for selecting substances having an ability to modulate activation of T cells are also disclosed. |
| FILED | Friday, February 17, 2012 |
| APPL NO | 13/399578 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461114 | Mei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lin Mei (Evans, Georgia); Yanmei Tao (Martinez, Georgia); Wen-Chen Xiong (Evans, Georgia) |
| ASSIGNEE(S) | Medical College of Georgia Research Institute, Inc. (Augusta, Georgia) |
| INVENTOR(S) | Lin Mei (Evans, Georgia); Yanmei Tao (Martinez, Georgia); Wen-Chen Xiong (Evans, Georgia) |
| ABSTRACT | Modulating the interaction between ErbB2 and Erbin is an effective method for treating one or more symptoms of ErbB2-mediated disorders. It has been discovered that Erbin stabilizes ErbB2 in vivo and inhibiting the formation of heterodimers between Erbin and ErbB2 reduces or inhibits the biological activity of ErbB2 relative to control levels. Reducing the biological activity of ErbB2 is useful in the treatment of conditions characterized by the overexpression or misregulation of ErbB2. These conditions include, but are not limited to breast cancer and prostate cancer. Alternatively, agonist of Erbin that promote or enhance the interaction of Erbin with ErbB2 can be useful in the treatment of certain neurological disorders. It has also been discovered that Erbin plays a role in the myelination of neurons of the peripheral nervous system. |
| FILED | Friday, May 14, 2010 |
| APPL NO | 12/780065 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461118 | Yates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Clayton Yates (Auburn, Alabama); Jesse Jaynes (Auburn, Alabama); Timothy Turner (Auburn, Alabama) |
| ASSIGNEE(S) | Tuskegee University (Tuskegge, Alabama) |
| INVENTOR(S) | Clayton Yates (Auburn, Alabama); Jesse Jaynes (Auburn, Alabama); Timothy Turner (Auburn, Alabama) |
| ABSTRACT | Lytic peptides, including fusion peptides of lytic peptides conjugated with luteinizing hormone-releasing hormone or modified versions thereof to target luteinizing hormone-releasing hormone receptors, are disclosed. The lytic peptides show anti-proliferative activity against human prostate cancer cell lines, but are nontoxic to normal primary human prostate epithelial cells or to bone marrow stromal cells in co-culture. The lytic peptides have specificity for and anti-proliferative activity against prostate cancer tumor cells, and low toxicity for normal prostate cells, making the peptides useful in therapies for prostate cancer. |
| FILED | Thursday, July 07, 2011 |
| APPL NO | 13/178042 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461119 | Pasquale et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elena B. Pasquale (San Diego, California); Mitchell Koolpe (San Diego, California); Keith K. Murai (Candiac, Canada) |
| ASSIGNEE(S) | The Burnham Institute (La Jolla, California) |
| INVENTOR(S) | Elena B. Pasquale (San Diego, California); Mitchell Koolpe (San Diego, California); Keith K. Murai (Candiac, Canada) |
| ABSTRACT | Novel agents are described that bind to Eph receptors. Methods of using these agents to modulate the activity of Eph receptors, stimulate apoptosis, and deliver therapeutic agents are also described. Methods of screening for agents capable of selectively binding to Eph receptors are also described. |
| FILED | Friday, August 29, 2003 |
| APPL NO | 10/652407 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461125 | Grunstein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael M. Grunstein (Merion Station, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michael M. Grunstein (Merion Station, Pennsylvania) |
| ABSTRACT | The present invention provides compositions and methods for the treatment of asthma. The compositions can be, for example, siRNA directed to CD23. The invention also provides a method of treating asthma with a formulation for in vivo delivery of a CD23 siRNA to inhibit IgE binding in a patient. |
| FILED | Friday, August 13, 2010 |
| APPL NO | 12/856130 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461127 | Scadden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David T. Scadden (Weston, Massachusetts); Tao Cheng (Newton, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David T. Scadden (Weston, Massachusetts); Tao Cheng (Newton, Massachusetts) |
| ABSTRACT | The expansion of a population of stem cells or progenitor cells, or precursors thereof, may be accomplished by disrupting or inhibiting p21cip1/waf1 and/or p27, cyclin dependent kinase inhibitors. In the absence of p27 activity, progenitor cells move into the cell cycle and proliferate; whereas in the absence of p21 activity, stem cells move into the cell cycle and proliferate without losing their pluripotentiality (i.e., their ability to differentiate into the various cell lines found in the blood stream). Any type of stem cell or progenitor cell, or precursor thereof, including, but not limited to, hematopoietic, gastrointestinal, lung, neural, skin, muscle, cardiac muscle, renal, mesenchymal, embryonic, fetal, or liver cell may be used in accordance with the invention. The present invention provides a method of expanding a cell population, cells with decreased p27 and/or p21 activity, transgenic animals with a disrupted p27 and/or p21 gene, pharmaceutical compositions comprising the cells of the invention, and methods of using these cells in gene therapy (e.g., stem cell gene therapy) and bone marrow transplantation. |
| FILED | Tuesday, January 03, 2012 |
| APPL NO | 13/342819 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461128 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Derek Shieh Tan (New York, New York); Luis E. N. Quadri (New York, New York); Jae-Sang Ryu (Seoul, South Korea); Justin Scott Cisar (New York, New York); Julian Alberto Ferreras (Roosevelt Island, New York); Xuequan Lu (Flushing, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York); Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Derek Shieh Tan (New York, New York); Luis E. N. Quadri (New York, New York); Jae-Sang Ryu (Seoul, South Korea); Justin Scott Cisar (New York, New York); Julian Alberto Ferreras (Roosevelt Island, New York); Xuequan Lu (Flushing, New York) |
| ABSTRACT | Many pathogens, including Mycobacterium tuberculosis and Yersinia pestis, rely on an iron acquisition system based on siderophores, secreted iron-chelating compounds with extremely high Fe(III) affinity. The compounds of the invention are inhibitors of domain salicylation enzymes, which catalyze the salicylation of an aroyl carrier protein (ArCP) domain to form a salicyl-ArCP domain thioester intermediate via a two-step reaction. The compounds include the intermediate mimic 5′-O—[N-(salicyl)sulfamoyl]-adenosine (salicyl-AMS) and analogs thereof. These compounds are inhibitors of the salicylate activity of MbtA, YbtE, PchD, and other domain salicylation enzymes involved in the biosynthesis of siderophores. Therefore, these compounds may be used in the treatment of infection caused by microorganisms which rely on siderphore-based iron acquisition systems. Pharmaceutical composition and methods of using these compounds to treat or prevent infection are also provided as well as methods of preparing the inventive compounds. |
| FILED | Friday, April 14, 2006 |
| APPL NO | 11/911525 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08461136 — Compositions and methods for protecting cells during cancer chemotherapy and radiotherapy
| US 08461136 | Fahl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William E. Fahl (Madison, Wisconsin); Nalini Raghavachari (Rockville, Maryland); Ming Zhu (Phoenix, Arizona); John A. Kink (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | William E. Fahl (Madison, Wisconsin); Nalini Raghavachari (Rockville, Maryland); Ming Zhu (Phoenix, Arizona); John A. Kink (Madison, Wisconsin) |
| ABSTRACT | Compositions, pharmaceutical preparations and methods are disclosed for protecting non-neoplastic cells from damage caused by cancer chemotherapeutic agents or radiation therapy, during the course of cancer therapy or bone marrow transplant. These are based on the use of chemoprotective inducing agents that induce or increase production of cellular detoxification enzymes in target cell populations. The compositions and methods are useful to reduce or prevent hair loss, gastrointestinal distress and lesions of the skin and oral mucosa that commonly occur in patients undergoing cancer therapy. Also disclosed is a novel assay system for identifying new chemoprotective inducing agents. |
| FILED | Monday, May 11, 2009 |
| APPL NO | 12/463789 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/97 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461153 | Glick |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gary D. Glick (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Gary D. Glick (Ann Arbor, Michigan) |
| ABSTRACT | The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone. |
| FILED | Thursday, October 27, 2011 |
| APPL NO | 13/283231 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/221 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461177 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dongcheng Dai (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon); Tove C. Bolken (Keizer, Oregon); Sean M. Amberg (Corvallis, Oregon); Ryan A. Larson (San Francisco, California) |
| ASSIGNEE(S) | Siga Technologies, Inc. (Corvallis, Oregon) |
| INVENTOR(S) | Dongcheng Dai (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon); Tove C. Bolken (Keizer, Oregon); Sean M. Amberg (Corvallis, Oregon); Ryan A. Larson (San Francisco, California) |
| ABSTRACT | Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever. |
| FILED | Tuesday, August 26, 2008 |
| APPL NO | 12/673983 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461201 | Petasis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nicos A. Petasis (Hacienda Heights, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Nicos A. Petasis (Hacienda Heights, California) |
| ABSTRACT | The invention features methods for the preparation of naturally occurring trihydroxy polyunsaturated eicosanoids and their structural analogs. The invention further provides new derivatives and analogs of trihydroxy polyunsaturated eicosanoids that can be prepared according to these methods. The invention also provides compositions and methods using trihydroxy polyunsaturated eicosanoid derivatives for the prevention, amelioration and treatment of a variety of diseases or conditions associated with inflammation or inflammatory response, autoimmune diseases, rheumatoid arthritis, cardiovascular diseases, or abnormal cell proliferation or cancer. |
| FILED | Monday, March 07, 2011 |
| APPL NO | 13/042156 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/546 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461225 | Muratoglu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Orhun K. Muratoglu (Cambridge, Massachusetts); Ebru Oral (Charlestown, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Orhun K. Muratoglu (Cambridge, Massachusetts); Ebru Oral (Charlestown, Massachusetts) |
| ABSTRACT | The present invention relates to methods for making oxidation resistant homogenized polymeric materials and medical implants that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and annealing the antioxidant doped UHMWPE in a super critical fluid, and materials used therein. |
| FILED | Friday, August 18, 2006 |
| APPL NO | 11/465544 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 522/75 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461298 | Bertozzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carolyn R. Bertozzi (Berkeley, California); Nicholas J. Agard (Berkeley, California); Jennifer A. Prescher (Berkeley, California); Jeremy Michael Baskin (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carolyn R. Bertozzi (Berkeley, California); Nicholas J. Agard (Berkeley, California); Jennifer A. Prescher (Berkeley, California); Jeremy Michael Baskin (Berkeley, California) |
| ABSTRACT | The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). |
| FILED | Monday, August 30, 2010 |
| APPL NO | 12/871800 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461311 | Hawkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William G. Hawkins (Olivette, Missouri); Dirk Spitzer (Webster Groves, Missouri); Richard S. Hotchkiss (Chesterfield, Missouri) |
| ASSIGNEE(S) | Washington University (Saint Louis, Missouri) |
| INVENTOR(S) | William G. Hawkins (Olivette, Missouri); Dirk Spitzer (Webster Groves, Missouri); Richard S. Hotchkiss (Chesterfield, Missouri) |
| ABSTRACT | Disclosed are TNF-related apoptosis-inducing ligand (TRAIL) trimers (TR3) and nucleic acids encoding covalently linked TRAIL trimers. A TRAIL trimer can have greater stability compared to native TRAIL, and can retain the native killing ability of TRAIL. Target specificity of a TR3 can be shown by blocking its activity with soluble death receptor 5 (DR5-Fc). Also disclosed are modified TRAIL trimers and nucleic. acids encoding them. These modifications include additional functional domains, such as antibody fragments (scFvs). A TR3 comprising an additional functional domain can allow for cell-specific delivery of the TR3. The inventors disclose TR3-decorated RBCs that target cell killing in a model of pancreatic cancer. |
| FILED | Wednesday, June 08, 2011 |
| APPL NO | 13/155577 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461314 | Ebright et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Richard H. Ebright (North Brunswick, New Jersey); Konstantin Severinov (Piscataway, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Richard H. Ebright (North Brunswick, New Jersey); Konstantin Severinov (Piscataway, New Jersey) |
| ABSTRACT | A nucleic acid sequence is provided, encoding at least one of a precursor of a lariat peptide, a processing factor of a lariat peptide, and an export factor of a lariat peptide, wherein the lariat peptide is a non-MccJ25 lariat peptide according to general structural formula (I) Also provided are biosynthesis systems useful for the synthesis of peptides according to formula (I), and methods of detecting and identifying nucleic acid sequences encoding the disclosed proteins. |
| FILED | Thursday, September 20, 2007 |
| APPL NO | 12/594152 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461319 | Pier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gerald B. Pier (Brookline, Massachusetts); Casie Anne Kelly-Quintos (Jamaica Plain, Massachusetts); Lisa Cavacini (Natick, Massachusetts); Marshall R. Posner (Medfield, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerald B. Pier (Brookline, Massachusetts); Casie Anne Kelly-Quintos (Jamaica Plain, Massachusetts); Lisa Cavacini (Natick, Massachusetts); Marshall R. Posner (Medfield, Massachusetts) |
| ABSTRACT | The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically to poly-N-acetyl glucosamine (PNAG), such as Staphylococcal PNAG, in acetylated, partially acetylated and/or fully deacetylated form. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy of infections by bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Some antibodies of the invention enhance opsonophagocytic killing and in vivo protection against bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides. |
| FILED | Thursday, December 22, 2011 |
| APPL NO | 13/334840 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461343 | Ouerfelli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ouathek Ouerfelli (Fort Lee, New Jersey); Anna Dilhas (Roosevelt Island, New York); Guangbin Yang (Forest Hills, New York); Hong Zhao (Rego Park, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Ouathek Ouerfelli (Fort Lee, New Jersey); Anna Dilhas (Roosevelt Island, New York); Guangbin Yang (Forest Hills, New York); Hong Zhao (Rego Park, New York) |
| ABSTRACT | A novel synthesis of the anti-androgen, A52, which has been found to be useful in the treatment of prostate cancer, is provided. A52 as well as structurally related analogs may be prepared via the inventive route. This new synthetic scheme may be used to prepare kilogram scale quantities of pure A52. |
| FILED | Thursday, March 27, 2008 |
| APPL NO | 12/450423 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/289 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461362 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ching-Shih Chen (Upper Arlington, Ohio); Dasheng Wang (Dublin, Ohio); Samuel K. Kulp (Hilliard, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ching-Shih Chen (Upper Arlington, Ohio); Dasheng Wang (Dublin, Ohio); Samuel K. Kulp (Hilliard, Ohio) |
| ABSTRACT | Tocopheryl succinate derivatives according to formula I: are described. These compounds increase the activity of protein phosphatase 2A, can be included in pharmaceutical compositions, and can be used for the treatment of androgen receptor-dependent cancers such as prostate cancer. |
| FILED | Tuesday, April 13, 2010 |
| APPL NO | 12/758858 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/407 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461521 | Vestal |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marvin L. Vestal (Framingham, Massachusetts) |
| ASSIGNEE(S) | Virgin Instruments Corporation (Sudbury, Massachusetts) |
| INVENTOR(S) | Marvin L. Vestal (Framingham, Massachusetts) |
| ABSTRACT | A time-of-flight mass spectrometer includes an ion source that generates ions. A two-field ion accelerator receives the ions generated by the ion source and generates an electric field that accelerates the ions through an ion flight path. A pulsed ion accelerator generates an accelerating electric field that focuses the ions to a focal plane where the ion flight time to the focal plane for an ion of predetermined mass-to-charge ratio is substantially independent to first order of an initial velocity of the ions prior to acceleration. An ion detector is positioned at the focal plane to detect ions. The two-field ion accelerator generates electric fields that cause the ion flight time to the ion detector for an ion of predetermined mass-to-charge ratio to be substantially independent to first order of both the initial position and the initial velocity of the ions prior to acceleration. |
| FILED | Tuesday, December 14, 2010 |
| APPL NO | 12/968254 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463353 | Seymour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John P. Seymour (Toledo, Ohio); Daryl R. Kipke (Dexter, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | John P. Seymour (Toledo, Ohio); Daryl R. Kipke (Dexter, Michigan) |
| ABSTRACT | In some embodiments, an implantable microelectrode is provided with a shank comprised of a laterally extending platform whose thickness and/or configuration contributes to reduced tissue encapsulation, with at least one electrode site disposed at least partially on or in the laterally extending platform. Novel methods of designing, making, and using an implantable microelectrode or biosensor resulting in reduced tissue encapsulation are also disclosed. |
| FILED | Wednesday, May 23, 2012 |
| APPL NO | 13/478746 |
| ART UNIT | 3739 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Surgery 6/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463366 | Freeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jenny E. Freeman (Chestnut Hill, Massachusetts); Edgar N. Lewis (Brookeville, Maryland) |
| ASSIGNEE(S) | Hypermed Imaging, Inc. (Greenwich, Connecticut); U.S. Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Jenny E. Freeman (Chestnut Hill, Massachusetts); Edgar N. Lewis (Brookeville, Maryland) |
| ABSTRACT | A medical instrument that comprises: a first-stage optic responsive to a tissue surface of a patient; a spectral separator optically responsive to the first stage optic and having a control input; an imaging sensor optically responsive to the spectral separator and having an image data output; and a diagnostic processor having an image acquisition interface with an input responsive to the imaging sensor and a filter control interface having a control output provided to the control input of the spectral separator. |
| FILED | Tuesday, November 22, 2011 |
| APPL NO | 13/303107 |
| ART UNIT | 3737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463383 | Sakai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Johnathan L. Sakai (Fairview Park, Ohio); Maria E. Bennett (Lyndhurst, Ohio); Joseph W. Boggs, II (Carrboro, North Carolina); Robert B. Strother (Willoughby Hills, Ohio); Geoffrey B. Thrope (Shaker Heights, Ohio); Kenneth P. Rundle (Independence, Ohio); Stuart F. Rubin (Orange Village, Ohio) |
| ASSIGNEE(S) | NDI Medical, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Johnathan L. Sakai (Fairview Park, Ohio); Maria E. Bennett (Lyndhurst, Ohio); Joseph W. Boggs, II (Carrboro, North Carolina); Robert B. Strother (Willoughby Hills, Ohio); Geoffrey B. Thrope (Shaker Heights, Ohio); Kenneth P. Rundle (Independence, Ohio); Stuart F. Rubin (Orange Village, Ohio) |
| ABSTRACT | Neurostimulation assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles and/or nerves inside the body and stimulus generators and/or recording instruments mounted on the surface of the skin or carried outside the body. Neurostimulation assemblies, systems, and methods may include a carrier and an electronics pod, the electronics pod including stimulation generation circuitry and user interface components. A power source and/or flash memory may be incorporated in neurostimulation assembly and/or the return electrode. The assemblies, systems, and methods are adapted to provide coordinated neurostimulation to multiple regions of the body. |
| FILED | Monday, August 03, 2009 |
| APPL NO | 12/462384 |
| ART UNIT | 3766 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463552 | Black et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevin J. Black (Crestwood, Missouri); Jonathan M. Koller (Crestwood, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin J. Black (Crestwood, Missouri); Jonathan M. Koller (Crestwood, Missouri) |
| ABSTRACT | The present invention is directed to systems and methods for diagnosing tissue abnormality or diseases, determining effective drug dosages, and monitoring therapeutic drug treatments. The methods and systems described utilize tissue imaging in situ and computer modeling. |
| FILED | Wednesday, October 18, 2006 |
| APPL NO | 11/583896 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463582 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dong Song (Irvine, California); Vasilis Z. Marmarelis (Rancho Palos Verdes, California); Theodore W. Berger (Rancho Palos Verdes, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Dong Song (Irvine, California); Vasilis Z. Marmarelis (Rancho Palos Verdes, California); Theodore W. Berger (Rancho Palos Verdes, California) |
| ABSTRACT | Systems and techniques, including machine-readable instructions, for modeling of nonlinear systems. In one aspect, an apparatus includes a collection of two or more inputs configured and arranged to receive input signals, a collection of two or more outputs configured and arranged to output output signals, a processing unit configured to transform the input signals into the output signals, wherein the transformation is non-linear and treats the non-linear system as a collection of multiple input, single output non-linear systems, and a data storage that stores characteristics of the transformation. |
| FILED | Monday, June 09, 2008 |
| APPL NO | 12/135904 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08459041 | Flanagan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Scott Flanagan (Simpsonville, South Carolina); Jeffrey Scott LeBegue (Simpsonville, South Carolina); Kevin Weston McMahan (Greer, South Carolina); Daniel Jackson Dillard (Greenville, South Carolina); Ronnie Ray Pentecost (Travelers Rest, South Carolina) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | James Scott Flanagan (Simpsonville, South Carolina); Jeffrey Scott LeBegue (Simpsonville, South Carolina); Kevin Weston McMahan (Greer, South Carolina); Daniel Jackson Dillard (Greenville, South Carolina); Ronnie Ray Pentecost (Travelers Rest, South Carolina) |
| ABSTRACT | A turbine system is disclosed. In one embodiment, the turbine system includes a transition duct. The transition duct includes an inlet, an outlet, and a passage extending between the inlet and the outlet and defining a longitudinal axis, a radial axis, and a tangential axis. The outlet of the transition duct is offset from the inlet along the longitudinal axis and the tangential axis. The transition duct further includes an interface member for interfacing with a turbine section. The turbine system further includes a leaf seal contacting the interface member to provide a seal between the interface member and the turbine section. |
| FILED | Wednesday, November 09, 2011 |
| APPL NO | 13/292366 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/796 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459084 | Krajewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul E. Krajewski (Troy, Michigan); Richard Harry Hammar (Shelby Township, Michigan); Jugraj Singh (Lake Orion, Michigan); Dennis Cedar (Rochester, Michigan); Peter A. Friedman (Ann Arbor, Michigan); Yingbing Luo (Ann Arbor, Michigan) |
| ASSIGNEE(S) | USAMP (Southfield, Michigan) |
| INVENTOR(S) | Paul E. Krajewski (Troy, Michigan); Richard Harry Hammar (Shelby Township, Michigan); Jugraj Singh (Lake Orion, Michigan); Dennis Cedar (Rochester, Michigan); Peter A. Friedman (Ann Arbor, Michigan); Yingbing Luo (Ann Arbor, Michigan) |
| ABSTRACT | An elevated temperature forming system in which a sheet metal workpiece is provided in a first stage position of a multi-stage pre-heater, is heated to a first stage temperature lower than a desired pre-heat temperature, is moved to a final stage position where it is heated to a desired final stage temperature, is transferred to a forming press, and is formed by the forming press. The preheater includes upper and lower platens that transfer heat into workpieces disposed between the platens. A shim spaces the upper platen from the lower platen by a distance greater than a thickness of the workpieces to be heated by the platens and less than a distance at which the upper platen would require an undesirably high input of energy to effectively heat the workpiece without being pressed into contact with the workpiece. |
| FILED | Thursday, February 05, 2009 |
| APPL NO | 12/366310 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal deforming 072/342.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459132 | Stoddard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nathan G. Stoddard (Gettysburg, Pennsylvania); Monte A. Lewis (Montgomery Village, Maryland); Roger F. Clark (Knoxville, Maryland) |
| ASSIGNEE(S) | Advanced Metallurgical Group Idealcast Solar Corp. (Wayne, Pennsylvania) |
| INVENTOR(S) | Nathan G. Stoddard (Gettysburg, Pennsylvania); Monte A. Lewis (Montgomery Village, Maryland); Roger F. Clark (Knoxville, Maryland) |
| ABSTRACT | Systems and methods are provided for monitoring a solid-liquid interface during a casting process. The systems and methods enable determination of the location of a solid-liquid interface during the casting process. |
| FILED | Monday, August 24, 2009 |
| APPL NO | 13/061077 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/866 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459185 | Jakaboski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Juan-Carlos Jakaboski (Albuquerque, New Mexico); Chance G. Hughs (Tijeras, New Mexico); Steven N. Todd (Rio Rancho, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Juan-Carlos Jakaboski (Albuquerque, New Mexico); Chance G. Hughs (Tijeras, New Mexico); Steven N. Todd (Rio Rancho, New Mexico) |
| ABSTRACT | A method for generating a projectile using an explosive device that can generate a projectile from the opposite side of a wall from the side where the explosive device is detonated. The projectile can be generated without breaching the wall of the structure or container. The device can optionally open an aperture in a solid wall of a structure or a container and form a high-kinetic-energy projectile from the portion of the wall removed to create the aperture. |
| FILED | Monday, September 12, 2011 |
| APPL NO | 13/230216 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/305 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459359 | Vinegar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Harold J. Vinegar (Bellaire, Texas) |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | Harold J. Vinegar (Bellaire, Texas) |
| ABSTRACT | A method for treating a nahcolite containing subsurface formation includes removing water from a saline zone in or near the formation. The removed water is heated using a steam and electricity cogeneration facility. The heated water is provided to the nahcolite containing formation. A fluid is produced from the nahcolite containing formation. The fluid includes at least some dissolved nahcolite. At least some of the fluid is provided to the saline zone. |
| FILED | Friday, April 18, 2008 |
| APPL NO | 12/106086 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Wells 166/303 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459572 | Hering et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susanne Hering (Berkeley, California); Gregory Lewis (Berkeley, California); Steven R. Spielman (Oakland, California) |
| ASSIGNEE(S) | Aerosol Dynamics Inc. (Berkeley, California) |
| INVENTOR(S) | Susanne Hering (Berkeley, California); Gregory Lewis (Berkeley, California); Steven R. Spielman (Oakland, California) |
| ABSTRACT | Technology is presented for the high efficiency concentration of fine and ultrafine airborne particles into a small fraction of the sampled airflow by condensational enlargement, aerodynamic focusing and flow separation. A nozzle concentrator structure including an acceleration nozzle with a flow extraction structure may be coupled to a containment vessel. The containment vessel may include a water condensation growth tube to facilitate the concentration of ultrafine particles. The containment vessel may further include a separate carrier flow introduced at the center of the sampled flow, upstream of the acceleration nozzle of the nozzle concentrator to facilitate the separation of particle and vapor constituents. |
| FILED | Friday, October 22, 2010 |
| APPL NO | 12/910705 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid sprinkling, spraying, and diffusing 239/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08459865 | Andraka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles E. Andraka (Albuquerque, New Mexico); Richard B. Diver, Jr. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Charles E. Andraka (Albuquerque, New Mexico); Richard B. Diver, Jr. (Albuquerque, New Mexico) |
| ABSTRACT | Innovative tracking heat flux sensors located at or near the solar collector's focus for centering the concentrated image on a receiver assembly. With flux sensors mounted near a receiver's aperture, the flux gradient near the focus of a dish or trough collector can be used to precisely position the focused solar flux on the receiver. The heat flux sensors comprise two closely-coupled thermocouple junctions with opposing electrical polarity that are separated by a thermal resistor. This arrangement creates an electrical signal proportional to heat flux intensity, and largely independent of temperature. The sensors are thermally grounded to allow a temperature difference to develop across the thermal resistor, and are cooled by a heat sink to maintain an acceptable operating temperature. |
| FILED | Tuesday, November 30, 2010 |
| APPL NO | 12/955954 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Thermal measuring and testing 374/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460409 | Hartvigsen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph J. Hartvigsen (Kaysville, Utah); S. Elangovan (South Jordan, Utah); Piotr Czernichowski (Layton, Utah); Michele Hollist (South Jordan, Utah) |
| ASSIGNEE(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Joseph J. Hartvigsen (Kaysville, Utah); S. Elangovan (South Jordan, Utah); Piotr Czernichowski (Layton, Utah); Michele Hollist (South Jordan, Utah) |
| ABSTRACT | A reformer is disclosed that includes a plasma zone to receive a pre-heated mixture of reactants and ionize the reactants by applying an electrical potential thereto. A first thermally conductive surface surrounds the plasma zone and is configured to transfer heat from an external heat source into the plasma zone. The reformer further includes a reaction zone to chemically transform the ionized reactants into synthesis gas comprising hydrogen and carbon monoxide. A second thermally conductive surface surrounds the reaction zone and is configured to transfer heat from the external heat source into the reaction zone. The first thermally conductive surface and second thermally conductive surface are both directly exposed to the external heat source. A corresponding method and system are also disclosed and claimed herein. |
| FILED | Friday, August 07, 2009 |
| APPL NO | 12/537953 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Gas: Heating and illuminating 048/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460532 | Bourcier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William L. Bourcier (Livermore, California); Roger D. Aines (Livermore, California); Jeffery J. Haslam (Livermore, California); Charlene M. Schaldach (Pleasanton, California); Kevin C. O'Brien (San Ramon, California); Edward Cussler (Edina, Minnesota) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | William L. Bourcier (Livermore, California); Roger D. Aines (Livermore, California); Jeffery J. Haslam (Livermore, California); Charlene M. Schaldach (Pleasanton, California); Kevin C. O'Brien (San Ramon, California); Edward Cussler (Edina, Minnesota) |
| ABSTRACT | The present invention provides a new method and apparatus/system for purifying ionic solutions, such as, for example, desalinating water, using engineered charged surfaces to sorb ions from such solutions. Surface charge is applied externally, and is synchronized with oscillatory fluid movements between substantially parallel charged plates. Ions are held in place during fluid movement in one direction (because they are held in the electrical double layer), and released for transport during fluid movement in the opposite direction by removing the applied electric field. In this way the ions, such as salt, are “ratcheted” across the charged surface from the feed side to the concentrate side. The process itself is very simple and involves only pumps, charged surfaces, and manifolds for fluid collection. |
| FILED | Tuesday, June 14, 2011 |
| APPL NO | 13/159862 |
| ART UNIT | 1756 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/663 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460672 | Yusim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karina Yusim (Santa Fe, New Mexico); Bette T. M. Korber (Los Alamos, New Mexico); Carla L. Kuiken (Santa Fe, New Mexico); William M. Fischer (Santa Fe, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Karina Yusim (Santa Fe, New Mexico); Bette T. M. Korber (Los Alamos, New Mexico); Carla L. Kuiken (Santa Fe, New Mexico); William M. Fischer (Santa Fe, New Mexico) |
| ABSTRACT | The invention relates to immunogenic compositions useful as HCV vaccines. Provided are HCV mosaic polypeptide and nucleic acid compositions which provide higher levels of T-cell epitope coverage while minimizing the occurrence of unnatural and rare epitopes compared to natural HCV polypeptides and consensus HCV sequences. |
| FILED | Wednesday, September 29, 2010 |
| APPL NO | 12/893731 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460782 | Ivanov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ilia N Ivanov (Knoxville, Tennessee); John T Simpson (Clinton, Tennessee); Troy R Hendricks (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ilia N Ivanov (Knoxville, Tennessee); John T Simpson (Clinton, Tennessee); Troy R Hendricks (Knoxville, Tennessee) |
| ABSTRACT | An array of aligned and dispersed carbon nanotubes includes an elongate drawn body including a plurality of channels extending therethrough from a first end to a second end of the body, where the channels have a number density of at least about 100,000 channels/mm2 over a transverse cross-section of the body. A plurality of carbon nanotubes are disposed in each channel, and the carbon nanotubes are sufficiently dispersed and aligned along a length of the channels for the array to comprise an average resistivity per channel of about 9700 Ωm or less. |
| FILED | Wednesday, May 16, 2012 |
| APPL NO | 13/472928 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Stock material or miscellaneous articles 428/297.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460823 | Delnick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frank M. Delnick (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Frank M. Delnick (Albuquerque, New Mexico) |
| ABSTRACT | A processed polysiloxane resin binder for use in electrochemical components and the method for fabricating components with the binder. The binder comprises processed polysiloxane resin that is partially oxidized and retains some of its methyl groups following partial oxidation. The binder is suitable for use in electrodes of various types, separators in electrochemical devices, primary lithium batteries, electrolytic capacitors, electrochemical capacitors, fuel cells and sensors. |
| FILED | Monday, December 20, 2010 |
| APPL NO | 12/973342 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/212 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460838 | Gillett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James E. Gillett (Greensburg, Pennsylvania); Paolo R. Zafred (Murrysville, Pennsylvania); Matthew W. Riggle (Ford City, Pennsylvania); Kevin P. Litzinger (Level Green, Pennsylvania) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | James E. Gillett (Greensburg, Pennsylvania); Paolo R. Zafred (Murrysville, Pennsylvania); Matthew W. Riggle (Ford City, Pennsylvania); Kevin P. Litzinger (Level Green, Pennsylvania) |
| ABSTRACT | A solid oxide fuel cell module contains a plurality of integral bundle assemblies, the module containing a top portion with an inlet fuel plenum and a bottom portion receiving air inlet feed and containing a base support, the base supports dense, ceramic exhaust manifolds which are below and connect to air feed tubes located in a recuperator zone, the air feed tubes passing into the center of inverted, tubular, elongated, hollow electrically connected solid oxide fuel cells having an open end above a combustion zone into which the air feed tubes pass and a closed end near the inlet fuel plenum, where the fuel cells comprise a fuel cell stack bundle all surrounded within an outer module enclosure having top power leads to provide electrical output from the stack bundle, where the fuel cells operate in the fuel cell mode and where the base support and bottom ceramic air exhaust manifolds carry from 85% to all 100% of the weight of the stack, and each bundle assembly has its own control for vertical and horizontal thermal expansion control. |
| FILED | Wednesday, August 19, 2009 |
| APPL NO | 12/543738 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/466 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461023 | Swiler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas P. Swiler (Albuquerque, New Mexico); Ernest J. Garcia (Albuquerque, New Mexico); Kathryn M. Francis (Rio Rancho, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Thomas P. Swiler (Albuquerque, New Mexico); Ernest J. Garcia (Albuquerque, New Mexico); Kathryn M. Francis (Rio Rancho, New Mexico) |
| ABSTRACT | A method is disclosed for singulating die from a semiconductor substrate (e.g. a semiconductor-on-insulator substrate or a bulk silicon substrate) containing an oxide layer (e.g. silicon dioxide or a silicate glass) and one or more semiconductor layers (e.g. monocrystalline or polycrystalline silicon) located above the oxide layer. The method etches trenches through the substrate and through each semiconductor layer about the die being singulated, with the trenches being offset from each other around at least a part of the die so that the oxide layer between the trenches holds the substrate and die together. The trenches can be anisotropically etched using a Deep Reactive Ion Etching (DRIE) process. After the trenches are etched, the oxide layer between the trenches can be etched away with an HF etchant to singulate the die. A release fixture can be located near one side of the substrate to receive the singulated die. |
| FILED | Tuesday, April 13, 2010 |
| APPL NO | 12/758838 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/464 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461300 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Bruce Robinson (Fremont, California); Ronald Zuckermann (El Cerrito, California); George M. Buffleben (Tracy, California) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | David Bruce Robinson (Fremont, California); Ronald Zuckermann (El Cerrito, California); George M. Buffleben (Tracy, California) |
| ABSTRACT | Sequence-specific polymers are proving to be a powerful approach to assembly and manipulation of matter on the nanometer scale. Ligands that are peptoids, or sequence-specific N-functional glycine oligomers, allow precise and flexible control over the arrangement of binding groups, steric spacers, charge, and other functionality. We have synthesized short peptoids that can prevent the aggregation of gold nanoparticles in high-salt environments including divalent salt, and allow co-adsorption of a single DNA molecule. This degree of precision and versatility is likely to prove essential in bottom-up assembly of nanostructures and in biomedical applications of nanomaterials. |
| FILED | Wednesday, January 12, 2011 |
| APPL NO | 13/005250 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/333 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461403 | Jasti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ramesh Jasti (Boston, Massachusetts); Carolyn Bertozzi (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ramesh Jasti (Boston, Massachusetts); Carolyn Bertozzi (Berkeley, California) |
| ABSTRACT | The present invention provides cycloparaphenylene compounds, their macrocyclic precursors, and methods for making the compounds. The cycloparaphenylene compounds can be used to prepare armchair carbon nanotubes. |
| FILED | Monday, November 29, 2010 |
| APPL NO | 12/955211 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461447 | Polcyn |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adam D. Polcyn (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | PPG Industries Ondo, Inc (Cleveland, Ohio) |
| INVENTOR(S) | Adam D. Polcyn (Pittsburgh, Pennsylvania) |
| ABSTRACT | A device for generating voltage or electrical current includes an inner elongated member mounted in an outer elongated member, and a plurality of thermoelectric modules mounted in the space between the inner and the outer members. The outer and/or inner elongated members each include a plurality of passages to move a temperature altering medium through the members so that the device can be used in high temperature environments, e.g. the exhaust system of an oxygen fired glass melting furnace. The modules are designed to include a biasing member and/or other arrangements to compensate for differences in thermal expansion between the first and the second members. In this manner, the modules remain in contact with the first and second members. The voltage generated by the modules can be used to power electrical loads. |
| FILED | Tuesday, December 18, 2007 |
| APPL NO | 11/958565 |
| ART UNIT | 1758 — Organic Chemistry |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/205 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461529 | Hunter |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott R. Hunter (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Scott R. Hunter (Oak Ridge, Tennessee) |
| ABSTRACT | A waveband imager includes an imaging pixel that utilizes photon tunneling with a thermally actuated bimorph structure to convert infrared radiation to visible radiation. Infrared radiation passes through a transparent substrate and is absorbed by a bimorph structure formed with a pixel plate. The absorption generates heat which deflects the bimorph structure and pixel plate towards the substrate and into an evanescent electric field generated by light propagating through the substrate. Penetration of the bimorph structure and pixel plate into the evanescent electric field allows a portion of the visible wavelengths propagating through the substrate to tunnel through the substrate, bimorph structure, and/or pixel plate as visible radiation that is proportional to the intensity of the incident infrared radiation. This converted visible radiation may be superimposed over visible wavelengths passed through the imaging pixel. |
| FILED | Thursday, September 23, 2010 |
| APPL NO | 12/889149 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461535 | Kuntz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joshua D. Kuntz (Livermore, California); Nerine J. Cherepy (Oakland, California); Jeffery J. Roberts (Livermore, California); Stephen A. Payne (Castro Valley, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Joshua D. Kuntz (Livermore, California); Nerine J. Cherepy (Oakland, California); Jeffery J. Roberts (Livermore, California); Stephen A. Payne (Castro Valley, California) |
| ABSTRACT | A transparent ceramic according to one embodiment includes a rare earth garnet comprising AhBiCjO12, where h is 3±10%, i is 2±10%, and j is 3±10%. A includes a rare earth element or a mixture of rare earth elements, B includes at least one of aluminum, gallium and scandium, and C includes at least one of aluminum, gallium and scandium, where A is at a dodecahedral site of the garnet, B is at an octahedral site of the garnet, and C is at a tetrahedral site of the garnet. In one embodiment, the rare earth garment has scintillation properties. A radiation detector in one embodiment includes a transparent ceramic as described above and a photo detector optically coupled to the rare earth garnet. |
| FILED | Tuesday, May 11, 2010 |
| APPL NO | 12/778007 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/361.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461546 | Payne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen A. Payne (Castro Valley, California); Wolfgang Stoeffl (Livermore, California); Natalia P. Zaitseva (Livermore, California); Nerine J. Cherepy (Oakland, California); M. Leslie Carman (San Ramon, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Stephen A. Payne (Castro Valley, California); Wolfgang Stoeffl (Livermore, California); Natalia P. Zaitseva (Livermore, California); Nerine J. Cherepy (Oakland, California); M. Leslie Carman (San Ramon, California) |
| ABSTRACT | One embodiment includes a material exhibiting an optical response signature for neutrons that is different than an optical response signature for gamma rays, said material exhibiting performance comparable to or superior to stilbene in terms of distinguishing neutrons from gamma rays, wherein the material is not stilbene. Another embodiment includes a substantially pure crystal exhibiting an optical response signature for neutrons that is different than an optical response signature for gamma rays, the substantially pure crystal comprising a material selected from a group consisting of: 1-1-4-4-tetraphenyl-1-3-butadiene; 2-fluorobiphenyl-4-carboxylic acid; 4-biphenylcarboxylic acid; 9-10-diphenylanthracene; 9-phenylanthracene; 1-3-5-triphenylbenzene; m-terphenyl; bis-MSB; p-terphenyl; diphenylacetylene; 2-5-diphenyoxazole; 4-benzylbiphenyl; biphenyl; 4-methoxybiphenyl; n-phenylanthranilic acid; and 1-4-diphenyl-1-3-butadiene. |
| FILED | Friday, April 03, 2009 |
| APPL NO | 12/418450 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/390.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461573 | Nastasi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Anthony Nastasi (Sante Fe, New Mexico); Yongqiang Wang (Los Alamos, New Mexico); Beatrice Fraboni (Bologna, Italy); Piero Cosseddu (Cagliari, Italy); Annalisa Bonfiglio (Cagliari, Italy) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Michael Anthony Nastasi (Sante Fe, New Mexico); Yongqiang Wang (Los Alamos, New Mexico); Beatrice Fraboni (Bologna, Italy); Piero Cosseddu (Cagliari, Italy); Annalisa Bonfiglio (Cagliari, Italy) |
| ABSTRACT | Organic thin film devices that included an organic thin film subjected to a selected dose of a selected energy of ions exhibited a stabilized mobility (μ) and threshold voltage (VT), a decrease in contact resistance RC, and an extended operational lifetime that did not degrade after 2000 hours of operation in the air. |
| FILED | Thursday, May 06, 2010 |
| APPL NO | 12/775056 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461600 | Ivanov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ilia N. Ivanov (Knoxville, Tennessee); John T. Simpson (Clinton, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ilia N. Ivanov (Knoxville, Tennessee); John T. Simpson (Clinton, Tennessee) |
| ABSTRACT | An electronic device comprises a drawn glass tube having opposing ends, a semiconductive material disposed inside of the drawn glass tube, and a first electrode and a second electrode disposed at the opposing ends of the drawn glass tube. A method of making an electrical device comprises disposing a semiconductive material inside of a glass tube, and drawing the glass tube with the semiconductive material disposed therein to form a drawn glass tube. The method of making an electrical device also comprises disposing a first electrode and a second electrode on the opposing ends of the drawn glass tube to form an electric device. |
| FILED | Friday, September 11, 2009 |
| APPL NO | 12/558129 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461620 | Glidden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven C. Glidden (Dryden, New York); Howard D. Sanders (Batavia, Illinois) |
| ASSIGNEE(S) | Applied Pulsed Power, Inc. (Freeville, New York) |
| INVENTOR(S) | Steven C. Glidden (Dryden, New York); Howard D. Sanders (Batavia, Illinois) |
| ABSTRACT | An optically triggered semiconductor switch includes an anode metallization layer; a cathode metallization layer; a semiconductor between the anode metallization layer and the cathode metallization layer and a photon source. The semiconductor includes at least four layers of alternating doping in the form P-N-P-N, in which an outer layer adjacent to the anode metallization layer forms an anode and an outer layer adjacent the cathode metallization layer forms a cathode and in which the anode metallization layer has a window pattern of optically transparent material exposing the anode layer to light. The photon source emits light having a wavelength, with the light from the photon source being configured to match the window pattern of the anode metallization layer. |
| FILED | Thursday, May 19, 2011 |
| APPL NO | 13/111170 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461762 | Rostoker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Norman Rostoker (Irvine, California); Michl Binderbauer (Irvine, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Norman Rostoker (Irvine, California); Michl Binderbauer (Irvine, California) |
| ABSTRACT | An apparatus and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy well, created by tuning an externally applied magnetic field. The simultaneous electrostatic confinement of electrons and magnetic confinement of ions avoids anomalous transport and facilitates classical containment of both electrons and ions. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions ions are fused together by nuclear force, thus releasing fusion energy. Moreover, the fusion fuel plasmas that can be used with the present confinement system and method are not limited to neutronic fuels only, but also advantageously include advanced fuels. |
| FILED | Wednesday, July 29, 2009 |
| APPL NO | 12/511266 |
| ART UNIT | 2821 — Electrical Circuits and Systems |
| CURRENT CPC | Electric lamp and discharge devices: Systems 315/111.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461989 | Romero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carlos E. Romero (Livermore, California); Peter C. Haugen (Livermore, California); James M. Zumstein (Livermore, California); Richard R. Leach, Jr. (Castro Valley, California); Mark L. Vigars (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | Carlos E. Romero (Livermore, California); Peter C. Haugen (Livermore, California); James M. Zumstein (Livermore, California); Richard R. Leach, Jr. (Castro Valley, California); Mark L. Vigars (Livermore, California) |
| ABSTRACT | An in-container monitoring sensor system is based on an UWB radar intrusion detector positioned in a container and having a range gate set to the farthest wall of the container from the detector. Multipath reflections within the container make every point on or in the container appear to be at the range gate, allowing intrusion detection anywhere in the container. The system also includes other sensors to provide false alarm discrimination, and may include other sensors to monitor other parameters, e.g. radiation. The sensor system also includes a control subsystem for controlling system operation. Communications and information extraction capability may also be included. A method of detecting intrusion into a container uses UWB radar, and may also include false alarm discrimination. A secure container has an UWB based monitoring system. |
| FILED | Friday, October 16, 2009 |
| APPL NO | 12/580379 |
| ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Communications: Electrical 340/541 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462528 | Kajouke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lateef A. Kajouke (San Pedro, California); Milun Perisic (Torrance, California); Ray M. Ransom (Big Bear City, California) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Lateef A. Kajouke (San Pedro, California); Milun Perisic (Torrance, California); Ray M. Ransom (Big Bear City, California) |
| ABSTRACT | Systems and methods are provided for delivering energy using an energy conversion module that includes one or more switching elements. An exemplary electrical system comprises a DC interface, an AC interface, an isolation module, a first conversion module between the DC interface and the isolation module, and a second conversion module between the AC interface and the isolation module. A control module is configured to operate the first conversion module to provide an injection current to the second conversion module to reduce a magnitude of a current through a switching element of the second conversion module before opening the switching element. |
| FILED | Monday, July 19, 2010 |
| APPL NO | 12/839134 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electric power conversion systems 363/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462824 | Popmintchev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tenio V. Popmintchev (Boulder, Colorado); Ming-Chang Chen (Boulder, Colorado); Alon Bahabad (Boulder, Colorado); Margaret M. Murnane (Boulder, Colorado); Henry C. Kapteyn (Boulder, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Tenio V. Popmintchev (Boulder, Colorado); Ming-Chang Chen (Boulder, Colorado); Alon Bahabad (Boulder, Colorado); Margaret M. Murnane (Boulder, Colorado); Henry C. Kapteyn (Boulder, Colorado) |
| ABSTRACT | Phase-matched high-order harmonic generation of soft and hard X-rays is accomplished using infrared driving lasers in a high-pressure non-linear medium. The pressure of the non-linear medium is increased to multi-atmospheres and a mid-IR (or higher) laser device provides the driving pulse. Based on this scaling, also a general method for global optimization of the flux of phase-matched high-order harmonic generation at a desired wavelength is designed. |
| FILED | Thursday, April 22, 2010 |
| APPL NO | 12/765859 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462987 | Cheriyadat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anil M. Cheriyadat (Knoxville, Tennessee); Richard J. Radke (Slingerlands, New York) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Anil M. Cheriyadat (Knoxville, Tennessee); Richard J. Radke (Slingerlands, New York) |
| ABSTRACT | Coherent motion regions extend in time as well as space, enforcing consistency in detected objects over long time periods and making the algorithm robust to noisy or short point tracks. As a result of enforcing the constraint that selected coherent motion regions contain disjoint sets of tracks defined in a three-dimensional space including a time dimension. An algorithm operates directly on raw, unconditioned low-level feature point tracks, and minimizes a global measure of the coherent motion regions. At least one discrete moving object is identified in a time series of video images based on the trajectory similarity factors, which is a measure of a maximum distance between a pair of feature point tracks. |
| FILED | Tuesday, June 23, 2009 |
| APPL NO | 12/489589 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463342 | Norem et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James H. Norem (Downers Grove, Illinois); Michael J. Pellin (Naperville, Illinois) |
| ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | James H. Norem (Downers Grove, Illinois); Michael J. Pellin (Naperville, Illinois) |
| ABSTRACT | Superconducting rf is limited by a wide range of failure mechanisms inherent in the typical manufacture methods. This invention provides a method for fabricating superconducting rf structures comprising coating the structures with single atomic-layer thick films of alternating chemical composition. Also provided is a cavity defining the invented laminate structure. |
| FILED | Monday, October 06, 2008 |
| APPL NO | 12/246223 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463495 | Spohn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian L. Spohn (Holly, Michigan); George M. Claypole (Fenton, Michigan); Richard D Starr (Milford, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Brian L. Spohn (Holly, Michigan); George M. Claypole (Fenton, Michigan); Richard D Starr (Milford, Michigan) |
| ABSTRACT | A method of operating a vehicle including an engine, a transmission, an exhaust gas heat recovery (EGHR) heat exchanger, and an oil-to-water heat exchanger providing selective heat-exchange communication between the engine and transmission. The method includes controlling a two-way valve, which is configured to be set to one of an engine position and a transmission position. The engine position allows heat-exchange communication between the EGHR heat exchanger and the engine, but does not allow heat-exchange communication between the EGHR heat exchanger and the oil-to-water heat exchanger. The transmission position allows heat-exchange communication between the EGHR heat exchanger, the oil-to-water heat exchanger, and the engine. The method also includes monitoring an ambient air temperature and comparing the monitored ambient air temperature to a predetermined cold ambient temperature. If the monitored ambient air temperature is greater than the predetermined cold ambient temperature, the two-way valve is set to the transmission position. |
| FILED | Wednesday, December 01, 2010 |
| APPL NO | 12/957755 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Gearing F16H 57/0413 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464040 | Ransom |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ray M. Ransom (Big Bear City, California) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Ray M. Ransom (Big Bear City, California) |
| ABSTRACT | Methods and apparatus are provided for enhancing the BIOS of a hardware peripheral device to manage multiple peripheral devices simultaneously without modifying the application software of the peripheral device. The apparatus comprises a logic control unit and a memory in communication with the logic control unit. The memory is partitioned into a plurality of ranges, each range comprising one or more blocks of memory, one range being associated with each instance of the peripheral application and one range being reserved for storage of a data pointer related to each peripheral application of the plurality. The logic control unit is configured to operate multiple instances of the control application by duplicating one instance of the peripheral application for each peripheral device of the plurality and partitioning a memory device into partitions comprising one or more blocks of memory, one partition being associated with each instance of the peripheral application. The method then reserves a range of memory addresses for storage of a data pointer related to each peripheral device of the plurality, and initializes each of the plurality of peripheral devices. |
| FILED | Wednesday, April 28, 2010 |
| APPL NO | 12/769462 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464143 | Olson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric J. Olson (Reno, Nevada) |
| ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education (Reno, Nevada) |
| INVENTOR(S) | Eric J. Olson (Reno, Nevada) |
| ABSTRACT | An apparatus, program product, and method that run an algorithm on a hardware based processor, generate a hardware error as a result of running the algorithm, generate an algorithm output for the algorithm, compare the algorithm output to another output for the algorithm, and detect the hardware error from the comparison. The algorithm is designed to cause the hardware based processor to heat to a degree that increases the likelihood of hardware errors to manifest, and the hardware error is observable in the algorithm output. As such, electronic components may be sufficiently heated and/or sufficiently stressed to create better conditions for generating hardware errors, and the output of the algorithm may be compared at the end of the run to detect a hardware error that occurred anywhere during the run that may otherwise not be detected by traditional methodologies (e.g., due to cooling, insufficient heat and/or stress, etc.). |
| FILED | Tuesday, January 12, 2010 |
| APPL NO | 12/657025 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/799 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08460428 | Lou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jun Lou (Houston, Texas); Yongjie Zhan (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jun Lou (Houston, Texas); Yongjie Zhan (Houston, Texas) |
| ABSTRACT | In various embodiments, methods for synthesizing single-crystalline zero-valent metal nanorings, such as single-crystalline copper nanorings, are described herein. The methods include providing a solution containing a metal cation, a complexing agent bound to the metal cation, thereby forming a metal complex that is at least partially soluble in the solution, and a reducing agent operable for reducing the metal complex to a zero-valent metal and then heating the solution for a sufficient time and at a sufficient temperature until zero-valent metal nanorings form. The solution may be an aqueous solution in an embodiment. Single-crystalline metal nanorings produced by the methods described herein may have a diameter less than about 100 μm and a wall thickness between about 10 nm and about 500 nm. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/771629 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/371 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460608 | Strano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael S. Strano (Lexington, Massachusetts); Daniel A. Heller (Rye Brook, New York); George W. Pratt (Melrose, Massachusetts); Jingqing Zhang (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael S. Strano (Lexington, Massachusetts); Daniel A. Heller (Rye Brook, New York); George W. Pratt (Melrose, Massachusetts); Jingqing Zhang (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods related to optical nanosensors comprising photoluminescent nanostructures are generally described. |
| FILED | Tuesday, December 14, 2010 |
| APPL NO | 12/967563 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460646 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Riyi Shi (West Lafayette, Indiana); Richard B. Borgens (Delphi, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Riyi Shi (West Lafayette, Indiana); Richard B. Borgens (Delphi, Indiana) |
| ABSTRACT | To achieve, an in vivo repair of injured mammalian nerve tissue, an effective amount of a biomembrane fusion agent is administered to the injured nerve tissue. The application of the biomembrane fusion agent may be performed by directly contacting the agent with the nerve tissue at the site of the injury. Alternatively, the biomembrane fusion agent is delivered to the site of the injury through the blood supply after administration of the biomembrane fusion agent to the patient. The administration is preferably by parenteral administration including intravascular, intramuscular, subcutaneous, or intraperitoneal injection of an effective quantity of the biomembrane fusion agent so that an effective amount is delivered to the site of the nerve tissue injury. |
| FILED | Thursday, July 23, 2009 |
| APPL NO | 12/508184 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460692 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Miqin Zhang (Bothell, Washington); Narayan Bhattarai (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Miqin Zhang (Bothell, Washington); Narayan Bhattarai (Seattle, Washington) |
| ABSTRACT | Alginate nanofibers, scaffolds that include alginate nanofibers, implantable devices that include alginate nanofibers, and methods for making the alginate nanofibers by electrospinning. |
| FILED | Thursday, February 09, 2012 |
| APPL NO | 13/370016 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460764 | de Heer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Walt A. de Heer (Atlanta, Georgia); Xuebin Li (Santa Clara, California); Michael Sprinkle (Mableton, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Walt A. de Heer (Atlanta, Georgia); Xuebin Li (Santa Clara, California); Michael Sprinkle (Mableton, Georgia) |
| ABSTRACT | In a method of producing ultra-thin graphitic layers, a carbide crystal is placed into a graphitic enclosure. The carbide crystal and the graphitic enclosure are placed into a chamber. The carbide crystal and the graphitic enclosure are subjected to a predetermined environment. Once the predetermined environment is established, the carbide crystal and the graphitic enclosure are heated to a first temperature for a predetermined period of time sufficient to cause at least one non-carbon element to evaporate from a crystal face of the carbide crystal so as to form at least one graphitic layer on the crystal face of the carbide crystal. |
| FILED | Wednesday, March 04, 2009 |
| APPL NO | 12/397894 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/595 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460785 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ilsoon Lee (Okemos, Michigan); Troy R. Hendricks (Knoxville, Tennessee) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Ilsoon Lee (Okemos, Michigan); Troy R. Hendricks (Knoxville, Tennessee) |
| ABSTRACT | Methods to control and prevent polymer films from buckling are provided. Buckled morphologies are created by thermally cycling or mechanically compressing a substrate such as poly(dimethylsiloxane) (PDMS) coated with a polyelectrolyte multilayer film. By varying the dimensions of the surface topography relative to the buckling wavelength (e.g., pattern size is less than, equal to, and greater than the buckling wavelength) the orientation and the local morphology of the buckled films is controlled. Based on the information obtained, we demonstrate how to alleviate the unavoidable buckling by incorporating nanoparticles into the film. In addition, we studied the effect of the silica layer that results from oxygen plasma treatment and the critical temperature for permanent film buckling. |
| FILED | Thursday, November 15, 2007 |
| APPL NO | 12/515155 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08460870 | Zocchi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Giovanni Zocchi (Los Angeles, California); Brian Choi (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Giovanni Zocchi (Los Angeles, California); Brian Choi (Los Angeles, California) |
| ABSTRACT | A method of altering the conformation of a polypeptide having a known three-dimensional structure is described. The method comprises attaching a first end of a polymer to a first portion of the polypeptide, attaching a second end of the polymer to a second portion of the polypeptide, and altering the mechanical tension of the polymer, thereby altering the conformation of the polypeptide. The alteration of the conformation of the polypeptide may increase or decrease the binding affinity of the polypeptide for a substrate bound by the polypeptide, or alter the catalytic rate of an enzyme. Typically, the polymer is a polynucleotide or polypeptide. |
| FILED | Wednesday, July 20, 2011 |
| APPL NO | 13/187351 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462040 | Venkatachalam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chandrasekaran Venkatachalam (Fort Collins, Colorado); Nitin Bharadwaj (Richland, Washington) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Chandrasekaran Venkatachalam (Fort Collins, Colorado); Nitin Bharadwaj (Richland, Washington) |
| ABSTRACT | Embodiments provide methods, systems, and/or devices that can provide measurements of the inherent reflectivity distribution from different look angles using N radar nodes. Doppler weather radars generally operate with very good spatial resolution in range and poor cross range resolution at farther ranges. Embodiments provide methodologies to retrieve higher resolution reflectivity data from a network of radars. In a networked radar environment, each radar may observe a common reflectivity distribution with different spreading function. The principle that the underlying reflectivity distribution should remain identical for all the nodes may be used to solve the inverse problem to determine intrinsic reflectivities. |
| FILED | Wednesday, October 20, 2010 |
| APPL NO | 12/908599 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/26.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462824 | Popmintchev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tenio V. Popmintchev (Boulder, Colorado); Ming-Chang Chen (Boulder, Colorado); Alon Bahabad (Boulder, Colorado); Margaret M. Murnane (Boulder, Colorado); Henry C. Kapteyn (Boulder, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Tenio V. Popmintchev (Boulder, Colorado); Ming-Chang Chen (Boulder, Colorado); Alon Bahabad (Boulder, Colorado); Margaret M. Murnane (Boulder, Colorado); Henry C. Kapteyn (Boulder, Colorado) |
| ABSTRACT | Phase-matched high-order harmonic generation of soft and hard X-rays is accomplished using infrared driving lasers in a high-pressure non-linear medium. The pressure of the non-linear medium is increased to multi-atmospheres and a mid-IR (or higher) laser device provides the driving pulse. Based on this scaling, also a general method for global optimization of the flux of phase-matched high-order harmonic generation at a desired wavelength is designed. |
| FILED | Thursday, April 22, 2010 |
| APPL NO | 12/765859 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462987 | Cheriyadat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anil M. Cheriyadat (Knoxville, Tennessee); Richard J. Radke (Slingerlands, New York) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Anil M. Cheriyadat (Knoxville, Tennessee); Richard J. Radke (Slingerlands, New York) |
| ABSTRACT | Coherent motion regions extend in time as well as space, enforcing consistency in detected objects over long time periods and making the algorithm robust to noisy or short point tracks. As a result of enforcing the constraint that selected coherent motion regions contain disjoint sets of tracks defined in a three-dimensional space including a time dimension. An algorithm operates directly on raw, unconditioned low-level feature point tracks, and minimizes a global measure of the coherent motion regions. At least one discrete moving object is identified in a time series of video images based on the trajectory similarity factors, which is a measure of a maximum distance between a pair of feature point tracks. |
| FILED | Tuesday, June 23, 2009 |
| APPL NO | 12/489589 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463053 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhen Guo (Elkins Park, Pennsylvania); Zhongfei (Mark) Zhang (Vestal, New York) |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Binghamton, New York) |
| INVENTOR(S) | Zhen Guo (Elkins Park, Pennsylvania); Zhongfei (Mark) Zhang (Vestal, New York) |
| ABSTRACT | Multimodal data mining in a multimedia database is addressed as a structured prediction problem, wherein mapping from input to the structured and interdependent output variables is learned. A system and method for multimodal data mining is provided, comprising defining a multimodal data set comprising image information; representing image information of a data object as a set of feature vectors in a feature space; clustering in the feature space to group similar features; associating a non-image representation with a respective image data object based on the clustering; determining a joint feature representation of a respective data object as a mathematical weighted combination of a set of components of the joint feature representation; optimizing a weighting for a plurality of components of the mathematical weighted combination with respect to a prediction error between a predicted classification and a training classification; and employing the mathematical weighted combination for automatically classifying a new data object. |
| FILED | Monday, August 10, 2009 |
| APPL NO | 12/538845 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/225 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463071 | Snavely et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Keith Noah Snavely (Seattle, Washington); Steven Maxwell Seitz (Seattle, Washington); Richard Szeliski (Bellevue, Washington) |
| ASSIGNEE(S) | Microsoft Corporation (Redmond, Washington); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Keith Noah Snavely (Seattle, Washington); Steven Maxwell Seitz (Seattle, Washington); Richard Szeliski (Bellevue, Washington) |
| ABSTRACT | Over the past few years there has been a dramatic proliferation of digital cameras, and it has become increasingly easy to share large numbers of photographs with many other people. These trends have contributed to the availability of large databases of photographs. Effectively organizing, browsing, and visualizing such .seas. of images, as well as finding a particular image, can be difficult tasks. In this paper, we demonstrate that knowledge of where images were taken and where they were pointed makes it possible to visualize large sets of photographs in powerful, intuitive new ways. We present and evaluate a set of novel tools that use location and orientation information, derived semi-automatically using structure from motion, to enhance the experience of exploring such large collections of images. |
| FILED | Tuesday, March 13, 2012 |
| APPL NO | 13/418774 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/284 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463374 | Hudson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John L. Hudson (Charlottesville, Virginia); István Z. Kiss (St. Louis, Missouri); Craig G. Rusin (West Seneca, New York); Hiroshi Kori (Tokyo, Japan) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | John L. Hudson (Charlottesville, Virginia); István Z. Kiss (St. Louis, Missouri); Craig G. Rusin (West Seneca, New York); Hiroshi Kori (Tokyo, Japan) |
| ABSTRACT | A method, apparatus, and computer program product for controlling the behavior of complex rhythmic systems, such as the nervous system, is disclosed. Robust, engineering based measurements of the rhythmic system are taken and used to generate feedback that guides the system towards a desired state. This methodically designed feedback allows the system to maintain the normal behavior of individual elements, thereby achieving high effectiveness, while at the same time minimizing side effects. It therefore becomes possible to move the system towards the desired state in a non-destructive manner. This approach also allows for increased flexibility and applicability because the feedback is generated in a manner that is tailored to the unique variables of the particular system. |
| FILED | Friday, June 27, 2008 |
| APPL NO | 12/665458 |
| ART UNIT | 3766 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463582 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dong Song (Irvine, California); Vasilis Z. Marmarelis (Rancho Palos Verdes, California); Theodore W. Berger (Rancho Palos Verdes, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Dong Song (Irvine, California); Vasilis Z. Marmarelis (Rancho Palos Verdes, California); Theodore W. Berger (Rancho Palos Verdes, California) |
| ABSTRACT | Systems and techniques, including machine-readable instructions, for modeling of nonlinear systems. In one aspect, an apparatus includes a collection of two or more inputs configured and arranged to receive input signals, a collection of two or more outputs configured and arranged to output output signals, a processing unit configured to transform the input signals into the output signals, wherein the transformation is non-linear and treats the non-linear system as a collection of multiple input, single output non-linear systems, and a data storage that stores characteristics of the transformation. |
| FILED | Monday, June 09, 2008 |
| APPL NO | 12/135904 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464143 | Olson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric J. Olson (Reno, Nevada) |
| ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education (Reno, Nevada) |
| INVENTOR(S) | Eric J. Olson (Reno, Nevada) |
| ABSTRACT | An apparatus, program product, and method that run an algorithm on a hardware based processor, generate a hardware error as a result of running the algorithm, generate an algorithm output for the algorithm, compare the algorithm output to another output for the algorithm, and detect the hardware error from the comparison. The algorithm is designed to cause the hardware based processor to heat to a degree that increases the likelihood of hardware errors to manifest, and the hardware error is observable in the algorithm output. As such, electronic components may be sufficiently heated and/or sufficiently stressed to create better conditions for generating hardware errors, and the output of the algorithm may be compared at the end of the run to detect a hardware error that occurred anywhere during the run that may otherwise not be detected by traditional methodologies (e.g., due to cooling, insufficient heat and/or stress, etc.). |
| FILED | Tuesday, January 12, 2010 |
| APPL NO | 12/657025 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/799 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08460919 | Selitrennikoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Claude P. Selitrennikoff (Highlands Ranch, Colorado); Tamara K. Miller (Wheatridge, Colorado) |
| ASSIGNEE(S) | GlobeImmune, Inc. (Louisville, Colorado) |
| INVENTOR(S) | Claude P. Selitrennikoff (Highlands Ranch, Colorado); Tamara K. Miller (Wheatridge, Colorado) |
| ABSTRACT | Embodiments of the present invention illustrate methods of treating and preventing infection due to a pathogen such as a fungal pathogen. In particular, the present invention relates to compositions and methods for vaccinations against or treatment for a fungal organism in a non-immunocompromised or immunocompromised subject. |
| FILED | Wednesday, September 30, 2009 |
| APPL NO | 12/570947 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/255.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461177 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dongcheng Dai (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon); Tove C. Bolken (Keizer, Oregon); Sean M. Amberg (Corvallis, Oregon); Ryan A. Larson (San Francisco, California) |
| ASSIGNEE(S) | Siga Technologies, Inc. (Corvallis, Oregon) |
| INVENTOR(S) | Dongcheng Dai (Corvallis, Oregon); Dennis E. Hruby (Albany, Oregon); Tove C. Bolken (Keizer, Oregon); Sean M. Amberg (Corvallis, Oregon); Ryan A. Larson (San Francisco, California) |
| ABSTRACT | Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever. |
| FILED | Tuesday, August 26, 2008 |
| APPL NO | 12/673983 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08461521 | Vestal |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marvin L. Vestal (Framingham, Massachusetts) |
| ASSIGNEE(S) | Virgin Instruments Corporation (Sudbury, Massachusetts) |
| INVENTOR(S) | Marvin L. Vestal (Framingham, Massachusetts) |
| ABSTRACT | A time-of-flight mass spectrometer includes an ion source that generates ions. A two-field ion accelerator receives the ions generated by the ion source and generates an electric field that accelerates the ions through an ion flight path. A pulsed ion accelerator generates an accelerating electric field that focuses the ions to a focal plane where the ion flight time to the focal plane for an ion of predetermined mass-to-charge ratio is substantially independent to first order of an initial velocity of the ions prior to acceleration. An ion detector is positioned at the focal plane to detect ions. The two-field ion accelerator generates electric fields that cause the ion flight time to the ion detector for an ion of predetermined mass-to-charge ratio to be substantially independent to first order of both the initial position and the initial velocity of the ions prior to acceleration. |
| FILED | Tuesday, December 14, 2010 |
| APPL NO | 12/968254 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08460868 | Brennan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark David Brennan (Jeffersonville, Indiana) |
| ASSIGNEE(S) | SureGene LLC (Louisville, Kentucky) |
| INVENTOR(S) | Mark David Brennan (Jeffersonville, Indiana) |
| ABSTRACT | The invention provides haplotypes and SNPs of the HPCAL1 and SV2C genes which predict the risk for developing schizophrenia or bipolar disorder and predict which patients are likely to respond to a given treatment or are more likely to experience negative side effects. |
| FILED | Monday, December 22, 2008 |
| APPL NO | 12/523243 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08462565 | Venugopal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sameer M. Venugopal (San Jose, California); David R. Allee (Phoenix, Arizona); Lawrence T. Clark (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Sameer M. Venugopal (San Jose, California); David R. Allee (Phoenix, Arizona); Lawrence T. Clark (Phoenix, Arizona) |
| ABSTRACT | Embodiments and examples of differential threshold voltage non-volatile memories and related methods are described herein. In one example, a method for providing an integrated circuit can comprise providing a memory cell coupled to a first bitline and to a second bitline, and at least one of (a) providing a read assist mechanism configured to couple to the memory cell via the first and second bitlines, or (b) providing a memory reset mechanism configured to couple to the memory cell via the first and second bitlines. Providing the memory cell can comprise providing a first transistor comprising a first threshold voltage, providing a second transistor comprising a second threshold voltage, and cross-coupling the first and second transistors of the memory cell together. A difference between the first and second threshold voltages can correspond to a logic state of the memory cell. Other embodiments, examples, and related methods are also disclosed herein. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/083427 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/189.150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08461085 | Weston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leslie A. Weston (Trumansburg, New York); Cecile Bertin (Montreal, Canada); Frank Schroeder (Ithaca, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Leslie A. Weston (Trumansburg, New York); Cecile Bertin (Montreal, Canada); Frank Schroeder (Ithaca, New York) |
| ABSTRACT | The present invention relates to methods of using m-tyrosine compounds from Festuca species for inhibiting weed growth and enhancing growth of non-weed plants. The present invention also relates to methods of identifying plants having herbicidal properties. |
| FILED | Wednesday, February 08, 2006 |
| APPL NO | 11/815823 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Plant protecting and regulating compositions 54/314 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08458899 | Mitchell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David J. Mitchell (Oviedo, Florida); Anand A. Kulkarni (Oviedo, Florida); Ramesh Subramanian (Oviedo, Florida); Edward R. Roesch (Orlando, Florida); Rod Waits (Sunnyvale, California); Roberto Schupbach (Fayetteville, Arkansas); John R. Fraley (Fayetteville, Arkansas); Alexander B. Lostetter (Fayetteville, Arkansas); Brice McPherson (Fayetteville, Arkansas); Bryon Western (West Fork, Arkansas) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | David J. Mitchell (Oviedo, Florida); Anand A. Kulkarni (Oviedo, Florida); Ramesh Subramanian (Oviedo, Florida); Edward R. Roesch (Orlando, Florida); Rod Waits (Sunnyvale, California); Roberto Schupbach (Fayetteville, Arkansas); John R. Fraley (Fayetteville, Arkansas); Alexander B. Lostetter (Fayetteville, Arkansas); Brice McPherson (Fayetteville, Arkansas); Bryon Western (West Fork, Arkansas) |
| ABSTRACT | A circuit assembly (34) resistant to high-temperature and high g centrifugal force is disclosed. A printed circuit board (42) is first fabricated from alumina and has conductive traces of said circuit formed thereon by the use of a thick film gold paste. Active and passive components of the circuit assembly are attached to the printed circuit board by means of gold powder diffused under high temperature. Gold wire is used for bonding between the circuit traces and the active components in order to complete the circuit assembly (34). Also, a method for manufacturing a circuit assembly resistant to elevated temperature is disclosed. |
| FILED | Monday, September 19, 2011 |
| APPL NO | 13/236083 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/831 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08461192 | Acevedo-Duncan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mildred Acevedo-Duncan (Plant City, Florida); Shraddha R. Desai (Tampa, Florida); Hla Yee Win (Tampa, Florida); David A. Ostrov (Gainesville, Florida); Prajit P. Pillai (Tampa, Florida); Diondra D. Hill (Tampa, Florida) |
| ASSIGNEE(S) | The University of South Florida (Tampa, Florida); The United States of America Department of Veterans Affairs (Washington, District of Columbia); The University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Mildred Acevedo-Duncan (Plant City, Florida); Shraddha R. Desai (Tampa, Florida); Hla Yee Win (Tampa, Florida); David A. Ostrov (Gainesville, Florida); Prajit P. Pillai (Tampa, Florida); Diondra D. Hill (Tampa, Florida) |
| ABSTRACT | PKCiota inhibitor 1H-imidazole-4-carboxamide, 5-amino-1-[2,3-dihydroxy-4-[(phosphonooxy)methyl]cyclopentyl]-,[1R-(1α,2β,3β,4α)], (ICA-1), targets a unique sequence (amino acid residues 469-475) in the catalytic domain of PKCiota and inhibits PKCiota activity. The data shows suprising and unexpected ability of ICA-1 to selectively inhibit the proliferation of cells that overexpress PKCiota. |
| FILED | Monday, September 15, 2008 |
| APPL NO | 12/210576 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/385 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08460796 | Sherman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew J. Sherman (Kirtland Hills, Ohio) |
| ASSIGNEE(S) | Mesocoat, Inc. (Euclid, Ohio) |
| INVENTOR(S) | Andrew J. Sherman (Kirtland Hills, Ohio) |
| ABSTRACT | A composite body that is spall resistant and comprises a substantially discontinuous cermet phase in a substantially continuous metal rich matrix phase. The composite body is typically bonded to a substrate to form a hardfacing on the substrate. The composite body exhibits ductile phase toughening with a strain to failure of at least about 2 percent, a modulus of elasticity of less than about 46 million pounds per square inch, and a density of less than about 7 grams per cubic centimeter. The metal rich matrix phase between the ceramic rich regions in the composite body has an average minimum span of about 0.5 to 8 microns to allow ductility in the composite body. The composite body has a Vicker's hardness number of greater than approximately 650. The discontinuous cermet phase is in the form of ceramic rich regions embedded within the composite body, and it includes ceramic particles and a cermet binder. The ceramic particles having a Moh's hardness of at least approximately 7.5, a modulus of elasticity of less than approximately 46 million pounds per square inch, and an average particle size of from about 0.1 to 10 microns. The ceramic rich regions exhibit high hardness as compared with the matrix phase. |
| FILED | Wednesday, February 03, 2010 |
| APPL NO | 12/699779 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/472 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08464007 | Abts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dennis C. Abts (Eleva, Wisconsin); Michael Higgins (Eau Claire, Wisconsin); Van L. Snyder (Blaine, Minnesota); Gerald A Schwoerer (Chippewa Falls, Wisconsin) |
| ASSIGNEE(S) | Cray Inc. (Seattle, Washington) |
| INVENTOR(S) | Dennis C. Abts (Eleva, Wisconsin); Michael Higgins (Eau Claire, Wisconsin); Van L. Snyder (Blaine, Minnesota); Gerald A Schwoerer (Chippewa Falls, Wisconsin) |
| ABSTRACT | Various embodiments include fault tolerant memory apparatus, methods, and systems, including a memory manager for supplying read and write requests to a memory device having a plurality of addressable memory locations. The memory manager includes a plurality of banks. Each bank includes a bank queue for storing read and write requests. The memory manager also includes a request arbiter connected to the plurality of banks. The request arbiter removes read and write requests from the bank queues for presentation to the memory device. The request arbiter includes a read phase of operation and a write phase of operation, wherein the request arbiter preferentially selects read requests for servicing during the read phase of operation and preferentially selects write requests for servicing during the write phase of operation. |
| FILED | Friday, June 12, 2009 |
| APPL NO | 12/484075 |
| ART UNIT | 2188 — AI & Simulation/Modeling |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/151 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 08460868 | Brennan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark David Brennan (Jeffersonville, Indiana) |
| ASSIGNEE(S) | SureGene LLC (Louisville, Kentucky) |
| INVENTOR(S) | Mark David Brennan (Jeffersonville, Indiana) |
| ABSTRACT | The invention provides haplotypes and SNPs of the HPCAL1 and SV2C genes which predict the risk for developing schizophrenia or bipolar disorder and predict which patients are likely to respond to a given treatment or are more likely to experience negative side effects. |
| FILED | Monday, December 22, 2008 |
| APPL NO | 12/523243 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08460675 | Kwak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Larry W. Kwak (Bellaire, Texas); Bira Arya (Baltimore, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of the Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Larry W. Kwak (Bellaire, Texas); Bira Arya (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a viral chemokine fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection. |
| FILED | Thursday, July 05, 2012 |
| APPL NO | 13/541997 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/192.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08463568 | Wynn |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey C. Wynn (Camas, Washington) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Interior (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey C. Wynn (Camas, Washington) |
| ABSTRACT | A system for mapping and characterizing a hydrocarbon plume in seawater by measuring seawater capacitance. Multiple streamer cables are towed in the sea behind a ship, each at a different depth, simultaneously. Each streamer cable includes transmitters and receivers at the free end thereof. The free ends of the streamer cables pass through the plume and the transmitters transmit an electrical current into the plume. The receivers detect any secondary signals produced by capacitive effects of the hydrocarbon or hydrocarbon and dispersant surrounded by conductive seawater in response to the inducing electrical current. Pre-amplifiers connected to the receivers and a two-step calibration procedure and various grounding and shielding steps provide noise rejection. An electronics system on board the ship processes the secondary signals to provide immediate development of detailed maps of plume location, and to provide tracking and characterization of how the plume changes shape and character over time. |
| FILED | Thursday, April 21, 2011 |
| APPL NO | 13/091314 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 11, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130611.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page