FedInvent™ Patents

Patent Details for Tuesday, October 01, 2013

This page was updated on Monday, March 27, 2023 at 03:51 AM GMT

Department of Defense (DOD)

08544340 — Device for testing thin specimens in pure bending

US 08544340	Ardelean et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Emil V. Ardelean (Albuquerque, New Mexico); Thomas W. Murphey (Albuquerque, New Mexico); Gregory E. Sanford (Albuquerque, New Mexico)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Emil V. Ardelean (Albuquerque, New Mexico); Thomas W. Murphey (Albuquerque, New Mexico); Gregory E. Sanford (Albuquerque, New Mexico)
ABSTRACT	An improved test fixture to evaluate thin composite laminates commonly used in deployable space structures. The fixture is designed to impart a pure moment into the coupon, a necessary improvement to prior test methods where results are obtained by fitting material properties in a nonlinear structural analysis of the test. Fixture mechanics allow for direct calculation of the coupon flexural modulus and allowable flexural strain based on two key measurements, fixture displacement and applied load.
FILED	Monday, September 26, 2011
APPL NO	13/245207
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/849
VIEW PATENT	@ USPTO: Full Text PDF

08544503 — Fluid conduit with self-healing protective sleeve

US 08544503	Barber et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	John R. Barber (Arlington, Texas); Brian P. Corbett (Fort Worth, Texas)
ASSIGNEE(S)	Bell Helicopter Textron Inc. (Fort Worth, Texas)
INVENTOR(S)	John R. Barber (Arlington, Texas); Brian P. Corbett (Fort Worth, Texas)
ABSTRACT	A fluid conduit having a self-healing sleeve in a spaced relationship from the conduit to provide protection against leaks due to ballistic projectiles, such as small arms fire.
FILED	Wednesday, May 31, 2006
APPL NO	12/279754
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Pipes and tubular conduits 138/110
VIEW PATENT	@ USPTO: Full Text PDF

08544764 — Fuel injector and operating method therefor

US 08544764	Cooke
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Michael Peter Cooke (Gillingham, United Kingdom)
ASSIGNEE(S)	Delphi Technologies Holding S.arl (Luxembourg, Luxembourg)
INVENTOR(S)	Michael Peter Cooke (Gillingham, United Kingdom)
ABSTRACT	A method of operating a fuel injector having a piezoelectric actuator for controlling movement of an injector valve needle comprises: (a) prior to an initial fuel injection event, reducing the voltage across the actuator at an initial rate so as to de-energize the actuator; (b) increasing the voltage across the actuator at a first rate in order to initiate an initial fuel injection event of a first fuel injection sequence; and (c) reducing the voltage across the actuator at a second rate in order to terminate the initial fuel injection event. The method may further comprise the step of: (d) increasing the voltage across the actuator at a third rate, which is lower than the first rate, so as to de-energize the actuator but without initiating an injection event, once the initial fuel injection event has terminated and before a subsequent fuel injection event is initiated. The method can be employed particularly to improve actuator lifespan, operating efficiency and/or performance in an energize to inject fuel injector.
FILED	Thursday, January 22, 2009
APPL NO	12/357634
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Fluid sprinkling, spraying, and diffusing 239/5
VIEW PATENT	@ USPTO: Full Text PDF

08544770 — Spray hole profile

US 08544770	Limmer et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Andrew J. Limmer (Bury St. Edmunds, United Kingdom); Ricardo Pimenta (Epsom, United Kingdom); Malcolm David Dick Lambert (West Wickham, United Kingdom); Celia C. Soteriou (Lyndhurst, United Kingdom)
ASSIGNEE(S)	Delphi Technologies (Luxembourg, Luxembourg); Holding S.arl (Luxembourg, Luxembourg)
INVENTOR(S)	Andrew J. Limmer (Bury St. Edmunds, United Kingdom); Ricardo Pimenta (Epsom, United Kingdom); Malcolm David Dick Lambert (West Wickham, United Kingdom); Celia C. Soteriou (Lyndhurst, United Kingdom)
ABSTRACT	A fuel injector for an internal combustion engine comprising a nozzle body having at least one spray hole. The at least one spray hole has a hole entry on the inside of the nozzle body and a hole exit on the outside of the nozzle body. The spray hole is provided with a hole entry section which, starting from the hole entry, has a flow area which decreases from a relatively larger flow area at the hole entry to a relatively small flow area at the intersection between the end of the hole entry section and the start of a hole exit section. The hole exit section, starting from the intersection with the hole entry section, has a flow area which increases from a relatively small flow area at the intersection with the hole entry section to a relatively larger flow area at the hole exit.
FILED	Thursday, June 26, 2008
APPL NO	12/215375
ART UNIT	3752 — Fluid Handling and Dispensing
CURRENT CPC	Fluid sprinkling, spraying, and diffusing 239/584
VIEW PATENT	@ USPTO: Full Text PDF

08545559 — Modified metal materials, surface modifications to improve cell interactions and antimicrobial properties, and methods for modifying metal surface properties

US 08545559	Bandyopadhyay et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)	Amit Bandyopadhyay (Pullman, Washington); Susmita Bose (Pullman, Washington)
ASSIGNEE(S)	Washington State University (Pullman, Washington)
INVENTOR(S)	Amit Bandyopadhyay (Pullman, Washington); Susmita Bose (Pullman, Washington)
ABSTRACT	The present disclosure is directed to modified metal materials for implantation and/or bone replacement, and to methods for modifying surface properties of metal substrates for enhancing cellular adhesion (tissue integration) and providing antimicrobial properties. Some embodiments comprise surface coatings for metal implants, such as titanium-based materials, using (1) electrochemical processing and/or oxidation methods, and/or (2) laser processing, in order to enhance bone cell-materials interactions and achieve improved antimicrobial properties. One embodiment comprises the modification of a metal surface by growth of in situ nanotubes via anodization, followed by electrodeposition of silver on the nanotubes. Other embodiments include the use of LENS™ processing to coat a metal surface with calcium-based bioceramic composition layers. These surface treatment methods can be applied as a post-processing operation to metallic implants such as hip, knee and spinal devices as well as screws, pins and plates.
FILED	Monday, October 06, 2008
APPL NO	12/246455
ART UNIT	3738 — Semiconductors/Memory
CURRENT CPC	Prosthesis 623/16.110
VIEW PATENT	@ USPTO: Full Text PDF

08545629 — Method and apparatus for producing large, single-crystals of aluminum nitride

US 08545629	Schowalter et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR) Missile Defense Agency (MDA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (Setauket, New York); Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Joseph A. Smart (Mooresville, North Carolina)
ASSIGNEE(S)	Crystal IS, Inc. (Green Island, New York)
INVENTOR(S)	Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (Setauket, New York); Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Joseph A. Smart (Mooresville, North Carolina)
ABSTRACT	Bulk single crystals of AlN having a diameter greater than about 25 mm and dislocation densities of about 10,000 cm⁻²or less and high-quality AlN substrates having surfaces of any desired crystallographic orientation fabricated from these bulk crystals.
FILED	Tuesday, May 09, 2006
APPL NO	11/431090
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/952
VIEW PATENT	@ USPTO: Full Text PDF

08545646 — High-density rocket propellant

US 08545646	Sanford et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Matthew J. Sanford (Bel Alton, Maryland); Randolph T. Johnson (Waldorf, Maryland); Paul G. Wallman (Indian Head, Maryland); Diana O. Bragunier (Indian Head, Maryland); Stephen N. Stiles (Indian Head, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Matthew J. Sanford (Bel Alton, Maryland); Randolph T. Johnson (Waldorf, Maryland); Paul G. Wallman (Indian Head, Maryland); Diana O. Bragunier (Indian Head, Maryland); Stephen N. Stiles (Indian Head, Maryland)
ABSTRACT	The present disclosure relates to a high-density rocket propellant and associated recoilless launching systems and methods with tungsten powder added providing substantial mass to the propellant for additional impulse, absorption of sound, optimization of back blast and carry weight, and the like. In an exemplary embodiment, the high-density rocket propellant includes tungsten mass percentages of between about 70%-about 80%, equivalent to about 17%-about 26% by volume.
FILED	Thursday, September 24, 2009
APPL NO	12/587319
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Explosive and thermic compositions or charges 149/42
VIEW PATENT	@ USPTO: Full Text PDF

08545814 — Non-invasive localization of a light-emitting conjugate in a mammal

US 08545814	Contag et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Redwood City, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Redwood City, California)
ABSTRACT	Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.
FILED	Wednesday, June 13, 2007
APPL NO	11/818208
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/9.600
VIEW PATENT	@ USPTO: Full Text PDF

08545983 — Super-low fouling sulfobetaine materials and related methods

US 08545983	Jiang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Shaoyi Jiang (Redmond, Washington); Shengfu Chen (Hangzhou, China PRC); Zheng Zhang (Cambridge, Massachusetts); Yung Chang (Lazhu Township, Taiwan)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Shaoyi Jiang (Redmond, Washington); Shengfu Chen (Hangzhou, China PRC); Zheng Zhang (Cambridge, Massachusetts); Yung Chang (Lazhu Township, Taiwan)
ABSTRACT	Super-low fouling sulfobetaine and carboxybetaine materials, super-low fouling surfaces and methods of making the surfaces coated with sulfobetaine and carboxybetaine materials, and devices having the super-low fouling surfaces.
FILED	Wednesday, December 08, 2010
APPL NO	12/963421
ART UNIT	1787 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/411.100
VIEW PATENT	@ USPTO: Full Text PDF

08545991 — Low thermal conductivity misfit layer compounds with layer to layer disorder

US 08545991	Johnson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) U.S. State Government State of Oregon
APPLICANT(S)	David C. Johnson (Eugene, Oregon); Ngoc T. Nguyen (Eugene, Oregon); Qiyin Lin (Darien, Illinois); Colby L. Heideman (Springfield, Oregon); Clay Mortensen (Portland, Oregon)
ASSIGNEE(S)	State of Oregon Acting by and Through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon)
INVENTOR(S)	David C. Johnson (Eugene, Oregon); Ngoc T. Nguyen (Eugene, Oregon); Qiyin Lin (Darien, Illinois); Colby L. Heideman (Springfield, Oregon); Clay Mortensen (Portland, Oregon)
ABSTRACT	Compositions comprise an alternating plurality of ordered layers of a first composition MX and a second composition TX₂, wherein M is one of Sn, Pb, Sb, Bi, or a rare earth metal, X is S or Se and T is Ti, V, Cr, Nb, or Ta. In some examples, the alternating plurality of ordered layers conforms to a substrate. In typical examples, each of the ordered layers of the first composition has a common thickness and/or each of the ordered layers of the first material has a common composition. In some examples, each of the ordered layers of the second composition has a common thickness and/or a common composition.
FILED	Monday, January 25, 2010
APPL NO	12/693376
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/635
VIEW PATENT	@ USPTO: Full Text PDF

08546002 — Yeast biofilm based fuel cell

US 08546002	Ganguli et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO)
APPLICANT(S)	Rahul Ganguli (Oak Park, California); Vivek Mehrotra (Simi Valley, California)
ASSIGNEE(S)	Teledyne Scientific and Imaging, LLC (Thousand Oaks, California)
INVENTOR(S)	Rahul Ganguli (Oak Park, California); Vivek Mehrotra (Simi Valley, California)
ABSTRACT	A yeast biofilm microbial fuel cell has anode and cathode chambers, each containing an electrolyte medium, separated by a proton conducting membrane. A baker's yeast biofilm is induced to form on the anode under electrical poising. A method of making the MFC includes adding baker's yeast and yeast nutrient fuel source to the anode solution, connecting a resistor across the anode and cathode to enable current flow through the resistor for a selected time for poising the anode and formation of the anodic yeast biofilm, replacing the anode solution with a fresh quantity of yeast-free solution, adding fuel source to the solution, and continuing to run the MFC for a selected time under resistance. The steps of replacing the anode solution, adding fuel source and running the cell under load are repeated until the baker's yeast has formed a suitable anodic biofilm.
FILED	Monday, October 26, 2009
APPL NO	12/606056
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/2
VIEW PATENT	@ USPTO: Full Text PDF

08546027 — System and method for directed self-assembly technique for the creation of carbon nanotube sensors and bio-fuel cells on single plane

US 08546027	Farrow et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Reginald C. Farrow (Somerset, New Jersey); Zafar Iqbal (Morristown, New Jersey); Alokik Kanwal (Princeton, New Jersey)
ASSIGNEE(S)	New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S)	Reginald C. Farrow (Somerset, New Jersey); Zafar Iqbal (Morristown, New Jersey); Alokik Kanwal (Princeton, New Jersey)
ABSTRACT	Improved nanotube devices and systems/methods for fabrication thereof are provided. The present disclosure provides systems/methods for depositing controlled numbers of nanotubes with specific properties at predefined locations for the fabrication of nanotube devices. The nanotube devices may be utilized in a range of applications. A bio-fuel cell system that does not require a proton exchange membrane separator and does not need a mediator to transfer charge is provided. This exemplary bio-fuel cell uses enzyme functionalized SWNTs for the anode/cathode. The absence of a membrane in the bio-fuel cell configuration opens up the possibility of other configurations that would otherwise be unfeasible. This includes a bio-fuel cell where the anode/cathode are on the same substrate. Since the electrodes can share the same substrate, the configuration may be integrated with a circuit device on the same substrate. An IC and its power source may be fabricated on the same silicon wafer.
FILED	Friday, March 12, 2010
APPL NO	12/722622
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/401
VIEW PATENT	@ USPTO: Full Text PDF

08546081 — Methods and compositions for assaying a sample for an aggregant

US 08546081	Bazan et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Singapore, Singapore)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Singapore, Singapore)
ABSTRACT	This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.
FILED	Monday, February 06, 2012
APPL NO	13/367358
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
VIEW PATENT	@ USPTO: Full Text PDF

08546313 — Nanotubular titania for decontamination of chemical warfare agents and toxic industrial chemicals

US 08546313	Wagner et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Aberdeen Proving Ground (APG) Research, Development and Engineering Command (RDECOM)
APPLICANT(S)	U.S. Army Research Development and Engineering Command (APG, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	George W. Wagner (Elkton, Maryland); Yue Wu (Chapel Hill, North Carolina); Alfred Kleinhammes (Chapel Hill, North Carolina)
ABSTRACT	The invention relates to methods and products enabling decontamination of chemical warfare agents and/or toxic industrial chemicals. More particularly, the invention pertains to improvements of surface decontamination processes using novel sorbents such as nanotubular titania.
FILED	Monday, November 26, 2012
APPL NO	13/685195
ART UNIT	1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Cleaning compositions for solid surfaces, auxiliary compositions therefor, or processes of preparing the compositions 510/110
VIEW PATENT	@ USPTO: Full Text PDF

08546505 — Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials

US 08546505	Zhang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Yadong Zhang (Alpharetta, Georgia); Seth Marder (Atlanta, Georgia); Carlos Zuniga (Atlanta, Georgia); Stephen Barlow (Atlanta, Georgia); Bernard Kippelen (Decatur, Georgia); Andreas Haldi (Dresden, Germany); Benoit Domerq (Waterloo, Belgium); Marcus Weck (New York, New York); Alpay Kimyonok (Besiktas Istanbul, Turkey)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Yadong Zhang (Alpharetta, Georgia); Seth Marder (Atlanta, Georgia); Carlos Zuniga (Atlanta, Georgia); Stephen Barlow (Atlanta, Georgia); Bernard Kippelen (Decatur, Georgia); Andreas Haldi (Dresden, Germany); Benoit Domerq (Waterloo, Belgium); Marcus Weck (New York, New York); Alpay Kimyonok (Besiktas Istanbul, Turkey)
ABSTRACT	This invention relates generally to norbornene-monomer, poly(norbornene)homopolymer, and poly(norbornene)copolymer compounds containing a functionalized carbazole side chain, having desirable solution processability and host characteristics. It also relates to hole transport and/or electron blocking materials, and to organic host materials for an organic luminescence layer, an OLED device, and compositions of matter which include these compounds.
FILED	Friday, December 19, 2008
APPL NO	12/808761
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 526/259
VIEW PATENT	@ USPTO: Full Text PDF

08546614 — Multifunctional crosslinkers for shape-memory polyimides, polyamides and poly(amide-imides) and methods of making the same

US 08546614	Tan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Loon-Seng Tan (Centerville, Ohio); David Huabin Wang (Beavercreek, Ohio)
ASSIGNEE(S)	The United States of America as represented by the Secretary of The Air Force (Washington, District of Columbia)
INVENTOR(S)	Loon-Seng Tan (Centerville, Ohio); David Huabin Wang (Beavercreek, Ohio)
ABSTRACT	Multifunctional amine crosslinkers that may be used to create crosslinked polyimide, polyamide, and poly(amide-imide) polymers and films having shape memory properties at elevated temperatures and methods of making the same.
FILED	Wednesday, July 25, 2012
APPL NO	13/557326
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Organic compounds 564/305
VIEW PATENT	@ USPTO: Full Text PDF

08546748 — Helium barrier atom chamber

US 08546748	Hughes et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Kenneth Jeramiah Hughes (Lafayette, Colorado); Charles Ackley Sackett (Charlottesville, Virginia); Archie Theodore Brown (Longmont, Colorado)
ASSIGNEE(S)	Triad Technology, Inc. (Longmont, Colorado)
INVENTOR(S)	Kenneth Jeramiah Hughes (Lafayette, Colorado); Charles Ackley Sackett (Charlottesville, Virginia); Archie Theodore Brown (Longmont, Colorado)
ABSTRACT	The present invention discloses a vacuum chamber having operating pressures in the ultra-high vacuum (UHV) range (10⁻⁸torr to 10⁻¹³torr) and incorporating transparent windows, said windows constructed from transparent materials (preferably glass), and having low helium permeability velocity under operating and storage conditions. Embodiments may also contain surface coatings on windows to reduce helium permeation. Also disclosed herein is a method for vacuum processing said chamber by heating entire chamber and exposing the inside and outside of the chamber windows to helium free environments. Methods for final sealing said chamber are also discussed. The vacuum chamber is useful as a container for optically-cooled atoms for use in quantum information and atomic clocks and as a sensor for magnetic fields, gravitational fields, and inertial effects.
FILED	Friday, April 06, 2012
APPL NO	13/441466
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/251
VIEW PATENT	@ USPTO: Full Text PDF

08546757 — Pixel structure for microbolometer detector

US 08546757	Hanson
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Charles M. Hanson (Richardson, Texas)
ASSIGNEE(S)	L-3 Communications Corporation (New York, New York)
INVENTOR(S)	Charles M. Hanson (Richardson, Texas)
ABSTRACT	Microbolometer pixel structures including membrane material in a current path between at least two spaced electrodes, the membrane material having multiple openings defined in the current path that are configured such that substantially the entire volume of electrically conductive membrane material in at least a portion of the current path contributes to conduction of current between the electrical contacts.
FILED	Wednesday, April 28, 2010
APPL NO	12/799627
ART UNIT	2884 — Optics
CURRENT CPC	Radiant energy 250/338.400
VIEW PATENT	@ USPTO: Full Text PDF

08546781 — Nitrogen doped aluminum oxide resistive random access memory

US 08546781	Wong et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Siu-Weng S. Wong (Woodside, California); Wanki Kim (White Plains, New York); Zhiping Zhang (Stanford, California); Sung Il Park (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Siu-Weng S. Wong (Woodside, California); Wanki Kim (White Plains, New York); Zhiping Zhang (Stanford, California); Sung Il Park (Stanford, California)
ABSTRACT	A resistive random access memory (RRAM) device is provided that includes a first electrode, a second electrode, and a resistance-change film disposed between the first electrode and the second electrode, where the resistance-change film includes an atomic ratio of aluminum, oxygen and nitrogen.
FILED	Friday, May 11, 2012
APPL NO	13/469556
ART UNIT	2896 — Optics
CURRENT CPC	Active solid-state devices 257/2
VIEW PATENT	@ USPTO: Full Text PDF

08546874 — Power switching semiconductor devices including rectifying junction-shunts

US 08546874	Hefner et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Allen Hefner (Darnestown, Maryland); Sei-Hyung Ryu (Cary, North Carolina); Anant Agarwal (Chapel Hill, North Carolina)
ASSIGNEE(S)	Cree, Inc. (Durham, North Carolina)
INVENTOR(S)	Allen Hefner (Darnestown, Maryland); Sei-Hyung Ryu (Cary, North Carolina); Anant Agarwal (Chapel Hill, North Carolina)
ABSTRACT	A semiconductor device includes a drift layer and a body region that forms a p-n junction with the drift layer. A contactor region is in the body region, and a shunt channel region extends through the body region from the contactor region to the drift layer. The shunt channel region has a length, thickness and doping concentration selected such that: 1) the shunt channel region is fully depleted when zero voltage is applied across the first and second terminals, 2) the shunt channel becomes conductive at a voltages less than the built-in potential of the drift layer to body region p-n junction, and/or 3) the shunt channel is not conductive for voltages that reverse bias the p-n junction between the drift region and the body region.
FILED	Friday, October 07, 2011
APPL NO	13/267966
ART UNIT	2826 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/328
VIEW PATENT	@ USPTO: Full Text PDF

08546896 — Magnetic tunneling junction elements having magnetic substructures(s) with a perpendicular anisotropy and memories using such magnetic elements

US 08546896	Lottis et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Daniel Lottis (Sunnyvale, California); Eugene Youjun Chen (Fremont, California); Xueti Tang (Fremont, California); Steven M. Watts (Mountain View, California)
ASSIGNEE(S)	Grandis, Inc. (San Jose, California)
INVENTOR(S)	Daniel Lottis (Sunnyvale, California); Eugene Youjun Chen (Fremont, California); Xueti Tang (Fremont, California); Steven M. Watts (Mountain View, California)
ABSTRACT	A method and system for providing a magnetic substructure usable in a magnetic device, as well as a magnetic element and memory using the substructure are described. The magnetic substructure includes a plurality of ferromagnetic layers and a plurality of nonmagnetic layers. The plurality of ferromagnetic layers are interleaved with the plurality of nonmagnetic layers. The plurality of ferromagnetic layers are immiscible with and chemically stable with respect to the plurality of nonmagnetic layers. The plurality of ferromagnetic layers are substantially free of a magnetically dead layer-producing interaction with the plurality of nonmagnetic layers. Further, the plurality of nonmagnetic layers induce a perpendicular anisotropy in the plurality of ferromagnetic layers. The magnetic substructure is configured to be switchable between a plurality of stable magnetic states when a write current is passed through the magnetic substructure.
FILED	Saturday, November 06, 2010
APPL NO	12/941031
ART UNIT	2814 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/421
VIEW PATENT	@ USPTO: Full Text PDF

08546906 — System and method for packaging of high-voltage semiconductor devices

US 08546906	Tipton, IV et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Charles Wesley Tipton, IV (Towson, Maryland); Oladimeji O Ibitayo (Baltimore, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Charles Wesley Tipton, IV (Towson, Maryland); Oladimeji O Ibitayo (Baltimore, Maryland)
ABSTRACT	A method and an electronic device structure comprising at least one access lead to adapted to be connected to an electrical circuit; at least one substrate region; at least one semiconductor die positioned on the substrate; the at least one semiconductor die being operatively connected to the at least one access lead; a dielectric region extending below the at least one semiconductor die; the dielectric region being formed by creating a cavity in the at least one substrate region; whereby the dielectric region operates to reduce electric field stresses produced by the at least one semiconductor die to thereby reduce the possibility of material failure and voltage breakdown. The method of making an electronic device structure comprises providing at least one substrate region; providing at least one semiconductor die located on the at least one substrate region; removing a portion of the at least one substrate region to provide a dielectric region within the substrate extending below the at least one semiconductor die; whereby the dielectric region within the at least one substrate region operates to reduce electric field stresses produced by the at least one semiconductor die to thereby reduce the possibility of material failure and voltage breakdown.
FILED	Tuesday, July 19, 2011
APPL NO	13/186021
ART UNIT	2822 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/487
VIEW PATENT	@ USPTO: Full Text PDF

08547004 — Encapsulated metal microtip microplasma devices, arrays and fabrication methods

US 08547004	Eden et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	J. Gary Eden (Champaign, Illinois); Sung-Jin Park (Champaign, Illinois); JeKwon Yoon (Paju-Si, South Korea); Brian Chung (Bloomingdale, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	J. Gary Eden (Champaign, Illinois); Sung-Jin Park (Champaign, Illinois); JeKwon Yoon (Paju-Si, South Korea); Brian Chung (Bloomingdale, Illinois)
ABSTRACT	An embodiment of the invention is a microtip microplasma device having a first metal microtip opposing a second metal microtip with a gap therebetween. The first and second metal microtips are encapsulated in metal oxide that electrically isolates and physically connects the first and second metal microtips. In preferred devices, the first and second metal microtips and metal oxide comprise a monolithic, unitary structure. Arrays can be flexible, can be arranged in stacks, and can be formed into cylinders, for example, for gas and liquid processing devices, air filters and other applications. A preferred method of to forming an array of microtip microplasma devices provides a metal mesh with an array of micro openings therein. Electrode areas of the metal mesh are masked leaving planned connecting metal oxide areas of the metal mesh unmasked. Planned connecting metal oxide areas are electrochemically etched to convert the planned connecting metal oxide areas to metal oxide that encapsulates opposing metal microtips therein. The mask is removed. The electrode areas are electrochemically etched to encapsulate the electrode areas in metal oxide.
FILED	Friday, July 22, 2011
APPL NO	13/188715
ART UNIT	2879 — Optics
CURRENT CPC	Electric lamp and discharge devices 313/267
VIEW PATENT	@ USPTO: Full Text PDF

08547178 — Single-event upset hardened ring oscillator

US 08547178	Wood et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Research Laboratory (NRL)
APPLICANT(S)	Neil E. Wood (Centreville, Virginia); Patrick Fleming (Arlington, Virginia); Andrew T. Kelly (Arlington, Virginia); Bin Li (Chantilly, Virginia); Daniel M. Pirkl (Centreville, Virginia)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Neil E. Wood (Centreville, Virginia); Patrick Fleming (Arlington, Virginia); Andrew T. Kelly (Arlington, Virginia); Bin Li (Chantilly, Virginia); Daniel M. Pirkl (Centreville, Virginia)
ABSTRACT	A ring oscillator is disclosed. The ring oscillator includes a first tri-path inverter, a second tri-path inverter and a third tri-path inverter. The second tri-path inverter is connected to the first tri-path inverter. The third tri-path inverter is connected to the first and second tri-path inverters to provide feedback for oscillations.
FILED	Friday, October 07, 2011
APPL NO	13/267925
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Oscillators 331/57
VIEW PATENT	@ USPTO: Full Text PDF

08547272 — Charge sharing analog computation circuitry and applications

US 08547272	Nestler et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Eric Nestler (Concord, Massachusetts); Vladimir Zlatkovic (Belmont, Massachusetts); Jeffrey Venuti (Bedford, Massachusetts)
ASSIGNEE(S)	Analog Devices, Inc. (Norwood, Massachusetts)
INVENTOR(S)	Eric Nestler (Concord, Massachusetts); Vladimir Zlatkovic (Belmont, Massachusetts); Jeffrey Venuti (Bedford, Massachusetts)
ABSTRACT	In one aspect, reduced power consumption and/or circuit area of a discrete time analog signal processing module is achieved in an approach that makes use of entirely, or largely, passive charge sharing circuitry, which may include configurable (e.g., after fabrication, at runtime) multiplicative scaling stages that do not require active devices in the signal path. In some examples, multiplicative coefficients are represented digitally, and are transformed to configure the reconfigurable circuitry to achieve a linear relationship between a desired coefficient and a degree of charge transfer. In some examples, multiple successive charge sharing phases are used to achieve a desired multiplicative effect that provides a large dynamic range of coefficients without requiring a commensurate range of sizes of capacitive elements. The scaling circuits can be combined to form configurable time domain or frequency domain filters.
FILED	Thursday, August 18, 2011
APPL NO	13/813101
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Coded data generation or conversion 341/172
VIEW PATENT	@ USPTO: Full Text PDF

08547280 — Systems and methods for exciting long slot radiators of an RF antenna

US 08547280	Yang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Fangchou Yang (Los Angeles, California); Hee Kyung Kim (El Segundo, California); Shahrokh Hashemi-Yeganeh (Rancho Palos Verdes, California); Clifton Quan (Arcadia, California); Alberto F. Viscarra (Torrance, California); Robert W. Ladera (Fullerton, California)
ASSIGNEE(S)	Raytheon Company (Waltham, Massachusetts)
INVENTOR(S)	Fangchou Yang (Los Angeles, California); Hee Kyung Kim (El Segundo, California); Shahrokh Hashemi-Yeganeh (Rancho Palos Verdes, California); Clifton Quan (Arcadia, California); Alberto F. Viscarra (Torrance, California); Robert W. Ladera (Fullerton, California)
ABSTRACT	Provided is a radiator transition assembly for exciting a long slot radiator of an antenna, the transition assembly including a folded flexible circuit substrate including at least two folds forming a long slot radiator, an excitation circuitry configured to generate signals for exciting the long slot radiator, and a microstrip transmission line coupled to the excitation circuitry and positioned along the folded flexible circuit substrate, where the microstrip transmission line extends across an opening of the long slot radiator.
FILED	Wednesday, July 14, 2010
APPL NO	12/836442
ART UNIT	2821 — Semiconductors/Memory
CURRENT CPC	Communications: Radio wave antennas 343/700.MS0
VIEW PATENT	@ USPTO: Full Text PDF

08547291 — Direct fed bifilar helix antenna

US 08547291	Josypenko
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Michael J. Josypenko (Norwich, Connecticut)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Michael J. Josypenko (Norwich, Connecticut)
ABSTRACT	The invention as disclosed is a direct fed bifilar helix antenna. The bifilar helix is lengthened as needed to obtain the desired unidirectional pattern. The bifilar helix is employed as an infinite balun to bring a feed cable onto the antenna structure and eventually connect the feed cable to the antenna feed point. The bifilar elements are widened such that the combined width of each element is as wide as practically possible before the elements touch and/or overlap (approximately 98.5% of the available width) so that the practical lowest characteristic impedance value of approximately 50 ohms is obtained so that there is no need for a matching network.
FILED	Friday, July 29, 2011
APPL NO	13/194345
ART UNIT	2821 — Semiconductors/Memory
CURRENT CPC	Communications: Radio wave antennas 343/895
VIEW PATENT	@ USPTO: Full Text PDF

08547549 — Substrate for surface enhanced Raman scattering (SERS)

US 08547549	Kuo et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Huei Pei Kuo (Cupertino, California); Jing Tang (Menlo Park, California); Fung Suong Ou (Houston, Texas); Zhiyong Li (Redwood City, California); Shih-Yuan Wang (Palo Alto, California)
ASSIGNEE(S)	Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S)	Huei Pei Kuo (Cupertino, California); Jing Tang (Menlo Park, California); Fung Suong Ou (Houston, Texas); Zhiyong Li (Redwood City, California); Shih-Yuan Wang (Palo Alto, California)
ABSTRACT	A substrate for Surface Enhanced Raman Scattering (SERS). The substrate comprises at least one nanostructure protruding from a surface of the substrate and a SERS active metal over the at least one nanostructure, wherein the SERS active metal substantially covers the at least one nanostructure and the SERS active metal creates a textured layer on the at least one nanostructure.
FILED	Monday, November 17, 2008
APPL NO	13/129571
ART UNIT	2877 — Optics
CURRENT CPC	Optics: Measuring and testing 356/301
VIEW PATENT	@ USPTO: Full Text PDF

08547846 — Method and apparatus providing precedence drop quality of service (PDQoS) with class-based latency differentiation

US 08547846	Ma et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Laura Jane Poplawski Ma (Somerville, Massachusetts); Frank Kastenholtz (Medford, Massachusetts); Gregory Stephen Lauer (Sudbury, Massachusetts); Walter Clark Milliken (Dover, New Hampshire); Gregory Donald Troxel (Stow, Massachusetts)
ASSIGNEE(S)	Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S)	Laura Jane Poplawski Ma (Somerville, Massachusetts); Frank Kastenholtz (Medford, Massachusetts); Gregory Stephen Lauer (Sudbury, Massachusetts); Walter Clark Milliken (Dover, New Hampshire); Gregory Donald Troxel (Stow, Massachusetts)
ABSTRACT	A packet is classified into a class. A priority value is assigned to the packet wherein packets in a flow are assigned priorities according to some probability distribution within some band. A determination is made, at a network device for a highest latency class, whether a sum of queued packet sizes of previously received packets having an equal or smaller latency class than the packet and larger or equal priority than the packet is larger than a threshold value. When the sum is larger, the packet is dropped, otherwise a determination is made whether a latency class of the packet is less than the latency class of the network device. When the latency class is not less, the packet is stored in a queue for the latency class. When the latency class is less, then the process is repeated until the packet is dropped or stored in a queue.
FILED	Monday, August 15, 2011
APPL NO	13/209646
ART UNIT	2465 — Multiplex and VoIP
CURRENT CPC	Multiplex communications 370/235
VIEW PATENT	@ USPTO: Full Text PDF

08547876 — Intermediate functional device and method

US 08547876	Clement et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Russel E. Clement (El Cajon, California); Ayax D. Ramirez (Chula Vista, California)
ASSIGNEE(S)	The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Russel E. Clement (El Cajon, California); Ayax D. Ramirez (Chula Vista, California)
ABSTRACT	A wireless intermediate functional device (IFD) for wireless communication between reduced functional devices in a star topology network having a central coordinator capable of operating as a network access device (NAD), and with fully functional devices in a mesh topology network also capable of operating as a NAD is described. The IFD is a wireless system that executes IEEE 802.15.4 standard compliant operations and operates as an intermediary between non-compatible devices. Various communication and protocol handshaking and management is facilitated by the IFD, allowing end devices in heterogeneous networks to communicate.
FILED	Wednesday, April 13, 2011
APPL NO	13/086265
ART UNIT	2475 — Multiplex and VoIP
CURRENT CPC	Multiplex communications 370/255
VIEW PATENT	@ USPTO: Full Text PDF

08548017 — Amplitude combining method for phase locking fiber lasers

US 08548017	O'Loughlin et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	James P. O'Loughlin (Albuquerque, New Mexico); Jeffry P. Heggemeier (Albuquerque, New Mexico); Roy A. Hamil (Albuquerque, New Mexico)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	James P. O'Loughlin (Albuquerque, New Mexico); Jeffry P. Heggemeier (Albuquerque, New Mexico); Roy A. Hamil (Albuquerque, New Mexico)
ABSTRACT	A method for implementing a coherent laser beam combining system in which a master laser oscillator output is split into N signals, fed through N phase adjusters and N amplifiers and combined in a coherent power combiner. The output of the combiner is sampled and sent to a processor. The processor selects one of the N phase adjusters, sweeps the phase in small steps over a 2π range, and locks the phase of that adjuster to the phase that corresponds to the maximum value of the combiner sample for that sweep cycle. The process is repeated for all the remaining phase adjusters resulting in maximizing the combiner output. The sweep cycles are repeated continuously to correct any phase errors that may occur over time. A similar method can be used in which both the polarizations and the phases of the N signals are maximized to thereby maximize the output of the coherent power combiner.
FILED	Tuesday, August 30, 2011
APPL NO	13/221450
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Coherent light generators 372/29.16
VIEW PATENT	@ USPTO: Full Text PDF

08548194 — System and method for determining altitude

US 08548194	Lyon
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	Jeffery A. Lyon (Coppell, Texas)
ASSIGNEE(S)	Mustang Tchnology Group, L.P. (Plano, Texas)
INVENTOR(S)	Jeffery A. Lyon (Coppell, Texas)
ABSTRACT	An altitude estimating system for use in a movable device, comprising: (i) circuitry for detecting, for each frame of a plurality of time frames, a set of present features external from the movable device; (ii) circuitry for providing, from a set of present features detected in a first frame, a set of predicted features that represent a prediction of location of the set of present features for a second frame that follows in time the first frame; (iii) circuitry for creating a set of correlated features by correlating a set of the predicted features for the second frame with a set of present features detected for the second frame; and (iv) circuitry for providing an estimated altitude in response to the set of correlated features.
FILED	Thursday, November 12, 2009
APPL NO	12/592642
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/103
VIEW PATENT	@ USPTO: Full Text PDF

08548231 — Predicate logic based image grammars for complex visual pattern recognition

US 08548231	Shet et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Vinay Damodar Shet (Princeton, New Jersey); Maneesh Kumar Singh (Lawrenceville, New Jersey); Claus Bahlmann (Princeton, New Jersey); Visvanathan Ramesh (Plainsboro, New Jersey); Stephen P. Masticola (Kingston, New Jersey); Jan Neumann (Arlington, Virginia); Toufiq Parag (Piscataway, New Jersey); Michael A. Gall (Belle Mead, New Jersey); Roberto Antonio Suarez (Jackson, New Jersey)
ASSIGNEE(S)	Siemens Corporation (Iselin, New Jersey)
INVENTOR(S)	Vinay Damodar Shet (Princeton, New Jersey); Maneesh Kumar Singh (Lawrenceville, New Jersey); Claus Bahlmann (Princeton, New Jersey); Visvanathan Ramesh (Plainsboro, New Jersey); Stephen P. Masticola (Kingston, New Jersey); Jan Neumann (Arlington, Virginia); Toufiq Parag (Piscataway, New Jersey); Michael A. Gall (Belle Mead, New Jersey); Roberto Antonio Suarez (Jackson, New Jersey)
ABSTRACT	First order predicate logics are provided, extended with a bilattice based uncertainty handling formalism, as a means of formally encoding pattern grammars, to parse a set of image features, and detect the presence of different patterns of interest implemented on a processor. Information from different sources and uncertainties from detections, are integrated within the bilattice framework. Automated logical rule weight learning in the computer vision domain applies a rule weight optimization method which casts the instantiated inference tree as a knowledge-based neural network, to converge upon a set of rule weights that give optimal performance within the bilattice framework. Applications are in (a) detecting the presence of humans under partial occlusions and (b) detecting large complex man made structures in satellite imagery (c) detection of spatio-temporal human and vehicular activities in video and (c) parsing of Graphical User Interfaces.
FILED	Tuesday, March 16, 2010
APPL NO	12/724954
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/156
VIEW PATENT	@ USPTO: Full Text PDF

08548287 — Direct interlayer optical coupler

US 08548287	Thacker et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Hiren D. Thacker (San Diego, California); Xuezhe Zheng (San Diego, California); Ivan Shubin (San Diego, California); Kannan Raj (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ASSIGNEE(S)	Oracle International Corporation (Redwood Shores, California)
INVENTOR(S)	Hiren D. Thacker (San Diego, California); Xuezhe Zheng (San Diego, California); Ivan Shubin (San Diego, California); Kannan Raj (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	In an MCM, an optical signal is conveyed by an optical waveguide disposed on a surface of a first substrate to an optical coupler having a vertical facet. This optical coupler has an optical mode that is different than the optical mode of the optical waveguide. For example, the spatial extent of the optical mode associated with the optical coupler may be larger, thereby reducing optical losses and sensitivity to alignment errors. Then, the optical signal is directly coupled from the vertical facet to a facing vertical facet of an identical optical coupler on another substrate, and the optical signal is conveyed in another optical waveguide disposed on the other substrate.
FILED	Thursday, November 10, 2011
APPL NO	13/293624
ART UNIT	2874 — Optics
CURRENT CPC	Optical waveguides 385/14
VIEW PATENT	@ USPTO: Full Text PDF

08548288 — Efficient inter-chip optical coupling

US 08548288	Raj et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Kannan Raj (San Diego, California); John E. Cunningham (San Diego, California); Hiren D. Thacker (San Diego, California)
ASSIGNEE(S)	Oracle International Corporation (Redwood Shores, California)
INVENTOR(S)	Kannan Raj (San Diego, California); John E. Cunningham (San Diego, California); Hiren D. Thacker (San Diego, California)
ABSTRACT	In an MCM, an optical signal is conveyed by an optical waveguide disposed on a surface of a first substrate to a first optical coupler. This first optical coupler redirects the optical signal out of the plane of the optical waveguide. Then, an optical interposer guides the optical signal between the first optical coupler and a second optical coupler on a surface of a second substrate, thereby reducing spatial expansion of the optical signal between the optical couplers. Moreover, the second optical coupler redirects the optical signal into a plane of an optical waveguide disposed on a surface of the second substrate, which then conveys the optical signal.
FILED	Tuesday, December 20, 2011
APPL NO	13/331782
ART UNIT	2874 — Optics
CURRENT CPC	Optical waveguides 385/14
VIEW PATENT	@ USPTO: Full Text PDF

08548314 — Articulated sensor support structure

US 08548314	Zwaan et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	John Peter Zwaan (Simi Valley, California); Makoto Ueno (Canoga Park, California); Marc L. Schmalzel (Simi Valley, California); Christopher E. Fisher (Simi Valley, California)
ASSIGNEE(S)	AeroVironment, Inc. (Monrovia, California)
INVENTOR(S)	John Peter Zwaan (Simi Valley, California); Makoto Ueno (Canoga Park, California); Marc L. Schmalzel (Simi Valley, California); Christopher E. Fisher (Simi Valley, California)
ABSTRACT	Embodiments include an assembly comprising: (a) a camera support structure comprising: a masthead disposed on the distal end of a mast wherein the masthead is configured to receive an imaging element; where a proximal end of the mast rotatably engaging an azimuth-elevation joint assembly wherein the azimuth-elevation joint assembly comprises a first angular actuator of a first rotational degree-of-freedom and a second angular actuator of a second rotational degree of freedom; and (b) a camera support structure housing comprising an aperture and a hatch wherein the hatch is resiliently biased to close the aperture; and wherein the camera support structure is configured to overcome the hatch resilient bias by at least one of: the release of a pin restraining a loaded spring and a rotational actuation of the mast via at least one of the first angular actuator and the second angular actuator.
FILED	Wednesday, May 23, 2012
APPL NO	13/478764
ART UNIT	2852 — Printing/Measuring and Testing
CURRENT CPC	Photography 396/12
VIEW PATENT	@ USPTO: Full Text PDF

08548572 — Determining inserted catheter end location and orientation

US 08548572	Crane
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Robert L. Crane (Kettering, Ohio)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Robert L. Crane (Kettering, Ohio)
ABSTRACT	Catheterization device and method of using are provided for uniquely illuminating the distal end of the device in order to visualize the end-point location and orientation and to track the movement of the catheterization device within passageways in the body. Use of the present invention by tracking in real time with an imaging device sensitive to visible to near infrared light. The invention allows the insertion and tracking of substantially any catheterization type device, for substantially any procedure requiring vascular access, such as in the placement of a PICC line, for heart catheterization or angioplasty, or for urinary track catheterization, or other bodily access procedure. The invention permits a technician to determine placement, orientation and movement of the device noninvasive equipment, without subjecting the patient to the hazards associated with ionizing radiation, radio frequency energy or significant thermal energy.
FILED	Monday, March 28, 2011
APPL NO	13/073296
ART UNIT	3768 — Printing/Measuring and Testing
CURRENT CPC	Surgery 6/476
VIEW PATENT	@ USPTO: Full Text PDF

08548650 — Hierarchical closed-loop control system for aircraft, missiles and munitions

US 08548650	Prince et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	Troy S. Prince (Cleveland, Ohio); Richard Kolacinski (South Euclid, Ohio); Mehul Patel (Streetsboro, Ohio)
ASSIGNEE(S)	Orbital Research Inc. (Cleveland, Ohio)
INVENTOR(S)	Troy S. Prince (Cleveland, Ohio); Richard Kolacinski (South Euclid, Ohio); Mehul Patel (Streetsboro, Ohio)
ABSTRACT	The present invention relates to a missile or munition with a hierarchical, modular, closed-loop flow control system, more particularly to aircraft or munition with flow control system for enhanced aerodynamic control, maneuverability and stabilization. The present invention further relates to a method of operating the flow control system. Various embodiments of the flow control system involve elements including flow sensors, active flow control devices or activatable flow effectors, and logic devices with closed loop control architecture. The sensors are used to estimate or determine flow conditions on the surfaces of a missile or munition. The active flow control device or activatable flow effectors create on-demand flow disturbances, preferably micro-disturbances, at different points along the various aerodynamic surfaces of the missile or aircraft to achieve a desired stabilization or maneuverability effect. The logic devices are embedded with a hierarchical control structure allowing for rapid, real-time control at the flow surface.
FILED	Wednesday, April 25, 2012
APPL NO	13/455182
ART UNIT	3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/3
VIEW PATENT	@ USPTO: Full Text PDF

08548794 — Statistical noun phrase translation

US 08548794	Koehn
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Philipp Koehn (Cambridge, Massachusetts)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Philipp Koehn (Cambridge, Massachusetts)
ABSTRACT	A statistical machine translation (MT) system may include a noun phrase/prepositional phrase (NP/PP) translation subsystem to translation NP/PPs as a subtask in an MT operation. The NP/PP translation subsystem may use a model trained on an NP/PP corpus and a decoder to generate an n-best list of candidate translations and a re-ranker to re-rank the candidate translations based on a machine learning method and additional features based on known properties of NP/PPs.
FILED	Friday, July 02, 2004
APPL NO	10/884175
ART UNIT	2659 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/4
VIEW PATENT	@ USPTO: Full Text PDF

08548837 — E-business value web

US 08548837	Ahern et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	Marybeth Ahern (Oak Hill, Virginia); Michael J. Law (Herndon, Virginia)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Marybeth Ahern (Oak Hill, Virginia); Michael J. Law (Herndon, Virginia)
ABSTRACT	A method and system is provided to manage and track changes in enterprise architectures. The invention provides a hierarchical visual management tool to manage and update relational information within an enterprise in a controlled fashion. The relationship may be maintained in a database and displayed via graphical user interface. Enterprise assets are categorized into such categories as goals, customer values or requirements, capabilities, resources, and the like. A hierarchy is constructed so that relationships between these various categories are identified and captured using the invention. Weights may be assigned to each element of the categories so that any proposed change to an enterprise architecture may be viewed so that a value can be ascertained and compared between other values of other proposed changes. In this manner, tracking and management of evolutionary changes to an architecture may be accomplished using relational information.
FILED	Wednesday, August 20, 2003
APPL NO	10/643987
ART UNIT	3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Data processing: Financial, business practice, management, or cost/price determination 75/7.120
VIEW PATENT	@ USPTO: Full Text PDF

08549208 — Cache memory having enhanced performance and security features

US 08549208	Lee et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Ruby B. Lee (Princeton, New Jersey); Zhenghong Wang (San Jose, California)
ASSIGNEE(S)	Teleputers, LLC (Princeton, New Jersey)
INVENTOR(S)	Ruby B. Lee (Princeton, New Jersey); Zhenghong Wang (San Jose, California)
ABSTRACT	A cache memory having enhanced performance and security feature is provided. The cache memory includes a data array storing a plurality of data elements, a tag array storing a plurality of tags corresponding to the plurality of data elements, and an address decoder which permits dynamic memory-to-cache mapping to provide enhanced security of the data elements, as well as enhanced performance. The address decoder receives a context identifier and a plurality of index bits of an address passed to the cache memory, and determines whether a matching value in a line number register exists. The line number registers allow for dynamic memory-to-cache mapping, and their contents can be modified as desired. Methods for accessing and replacing data in a cache memory are also provided, wherein a plurality of index bits and a plurality of tag bits at the cache memory are received. The plurality of index bits are processed to determine whether a matching index exists in the cache memory and the plurality of tag bits are processed to determine whether a matching tag exists in the cache memory, and a data line is retrieved from the cache memory if both a matching tag and a matching index exist in the cache memory. A random line in the cache memory can be replaced with a data line from a main memory, or evicted without replacement, based on the combination of index and tag misses, security contexts and protection bits. User-defined and/or vendor-defined replacement procedures can be utilized to replace data lines in the cache memory.
FILED	Tuesday, December 08, 2009
APPL NO	12/633500
ART UNIT	2188 — Computer Architecture and I/O
CURRENT CPC	Electrical computers and digital processing systems: Memory 711/3
VIEW PATENT	@ USPTO: Full Text PDF

08549285 — Method and apparatus for anonymous IP datagram exchange using dynamic network address translation

US 08549285	Fink et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	Russell A. Fink (Columbia, Maryland); Edward A. Bubnis, Jr. (Catonsville, Maryland); Thomas E. Keller (Ellicott City, Maryland)
ASSIGNEE(S)	Verizon Corporate Services Group Inc. (Basking Ridge, New Jersey); Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S)	Russell A. Fink (Columbia, Maryland); Edward A. Bubnis, Jr. (Catonsville, Maryland); Thomas E. Keller (Ellicott City, Maryland)
ABSTRACT	Methods, apparatus, system and computer program are provided for concealing the identity of a network device transmitting a datagram having a network layer header. A unique local identifier and broadcast address are determined in accordance with a next-hop address. A partially encrypted network layer header is determined by encrypting a plurality of identifying portions of the network layer header, where one portion of the network layer header is the unique local identifier. The datagram is encapsulated with another network layer header whose address is set to the broadcast address. The encapsulated datagram can be received and detunneled, and an address of a recipient can be extracted from the network layer header. The datagram is then admitted into a network domain.
FILED	Monday, June 14, 2010
APPL NO	12/814624
ART UNIT	2436 — Cryptography and Security
CURRENT CPC	Electrical computers and digital processing systems: Support 713/162
VIEW PATENT	@ USPTO: Full Text PDF

08549543 — Virtualize, checkpoint, and restart POSIX IPC objects during checkpointing and restarting of a software partition

US 08549543	Kharat et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Satish Narayan Kharat (Bangalore, India); Rajeev Mishra (Bangalore, India); Lance Warren Russell (Rosanky, Texas); Suresh Sabarathinam (Austin, Texas)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Satish Narayan Kharat (Bangalore, India); Rajeev Mishra (Bangalore, India); Lance Warren Russell (Rosanky, Texas); Suresh Sabarathinam (Austin, Texas)
ABSTRACT	A WPAR is migrated. Responsive to starting a checkpoint process, data and control information is collected and stored for IPC objects in the WPAR. Responsive to receiving a request to restart the WPAR, a type of IPC object is determined. Responsive to a determination that the IPC object is not an IPC shared memory object, a kernel handle that a process wants to be used for a new IPC object is registered. A request to create a new IPC object comprising a name uniquely associated with the IPC object and a WPAR identifier is issued. An entry that matches the name and WPAR identifier is identified and a virtual kernel handle is retrieved. The new IPC object is created. The virtual kernel handle is mapped to a real kernel handle and returned to the process. Data and control information is retrieved and overlaid onto the new IPC object.
FILED	Tuesday, September 30, 2008
APPL NO	12/242218
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/319
VIEW PATENT	@ USPTO: Full Text PDF

08549646 — Methods, media and systems for responding to a denial of service attack

US 08549646	Stavrou et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Angelos Stavrou (New York, New York); Angelos D. Keromytis (New York, New York); Jason Nieh (New York, New York); Vishal Misra (New York, New York); Daniel Rubenstein (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Angelos Stavrou (New York, New York); Angelos D. Keromytis (New York, New York); Jason Nieh (New York, New York); Vishal Misra (New York, New York); Daniel Rubenstein (New York, New York)
ABSTRACT	Methods, media and systems for responding to a Denial of Service (DoS) attack are provided. In some embodiments, a method includes detecting a DoS attack, migrating one or more processes that provide a service to an unaffected system; authenticating users that are authorized to use the service; and routing traffic generated by authenticated users to the unaffected system.
FILED	Friday, October 20, 2006
APPL NO	11/584312
ART UNIT	2433 — Cryptography and Security
CURRENT CPC	Information security 726/24
VIEW PATENT	@ USPTO: Full Text PDF

08549647 — Classifying portable executable files as malware or whiteware

US 08549647	Mason et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Mark Mason (San Antonio, Texas); Ming-Shih Wong (San Antonio, Texas); Jeff Rhines (Adkins, Texas); Josh Mitchell (San Antonio, Texas)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Mark Mason (San Antonio, Texas); Ming-Shih Wong (San Antonio, Texas); Jeff Rhines (Adkins, Texas); Josh Mitchell (San Antonio, Texas)
ABSTRACT	An improved approach for classifying portable executable files as malicious (malware) or benign (whiteware) is disclosed. The invention classifies portable executable files as malware or whiteware after using Bayes Theorem to evaluate each observable feature of each file with respect to other observable features of the same portable executable file with reference to statistical information gathered from repositories of known whiteware and malware files.
FILED	Friday, January 14, 2011
APPL NO	13/007265
ART UNIT	2432 — Cryptography and Security
CURRENT CPC	Information security 726/24
VIEW PATENT	@ USPTO: Full Text PDF

08549661 — Apparatus for performing magnetic resonance force microscopy on large area samples

US 08549661	Smith
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Doran Smith (Rockville, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Doran Smith (Rockville, Maryland)
ABSTRACT	An apparatus for performing magnetic resonance force microscopy on one or more large area samples comprising a base plate, one or more heat sink plates coupled to the base plate, one or more suspension mechanisms coupled to the base plate and the heat sink plates, a probe head suspended from the one or more suspension mechanisms for scanning the one or more samples and a sample cylinder comprising a sample stage coupled to the probe head for sample positioning and an outer drum for isolating the sample stage.
FILED	Monday, January 30, 2012
APPL NO	13/361223
ART UNIT	2881 — Optics
CURRENT CPC	Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/43
VIEW PATENT	@ USPTO: Full Text PDF

Department of Health and Human Services (HHS)

08544462 — Systems and methods for aerosol delivery of agents

US 08544462	Papania et al.
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC)
APPLICANT(S)	Mark James Papania (Lilburn, Georgia); James J. Barry (Hanover, New Hampshire); Nabil A. Elkouh (Meriden, New Hampshire); Mark C. Bagley (Grafton, New Hampshire)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia); Creare Incorporated (Hanover, New Hampshire)
INVENTOR(S)	Mark James Papania (Lilburn, Georgia); James J. Barry (Hanover, New Hampshire); Nabil A. Elkouh (Meriden, New Hampshire); Mark C. Bagley (Grafton, New Hampshire)
ABSTRACT	Aerosol delivery systems and methods for delivering an agent to a patient are described herein. In particular embodiments, an insulated receptacle is connected to a housing and holds a vial of an agent to be delivered to a patient. The vial is located in an inverted position within the receptacle. One or more reusable thermal packs can be located on the inner sides of the receptacle, to maintain a selected temperature surrounding the vial. The agent is administered to a patient by placing a prong into one of the patient's orifices and then activating an aerosol delivery system. Such systems can include jet aerosolization and pneumatic and ultrasonic nebulizers and preferably are portable.
FILED	Friday, April 27, 2007
APPL NO	11/796313
ART UNIT	3778 — Printing/Measuring and Testing
CURRENT CPC	Surgery 128/200.160
VIEW PATENT	@ USPTO: Full Text PDF

08545416 — Integrated diagnostic and therapeutic system and method for improving treatment of subject with complex and central sleep apnea

US 08545416	Kayyali et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Hani Kayyali (Shaker Heights, Ohio); Dan Bishop (Tallmadge, Ohio); Brian M. Kolkowski (Leroy, Ohio)
ASSIGNEE(S)	Cleveland Medical Devices Inc. (Cleveland, Ohio)
INVENTOR(S)	Hani Kayyali (Shaker Heights, Ohio); Dan Bishop (Tallmadge, Ohio); Brian M. Kolkowski (Leroy, Ohio)
ABSTRACT	The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.
FILED	Thursday, July 19, 2007
APPL NO	11/880046
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/534
VIEW PATENT	@ USPTO: Full Text PDF

08545543 — Methods and apparatus for microstructure lightguides

US 08545543	Zorzos et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) NIH Office of the Director (NIHOD) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Anthony Zorzos (Cambridge, Massachusetts); Clifton Fonstad (Arlington, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts); Jacob Bernstein (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Anthony Zorzos (Cambridge, Massachusetts); Clifton Fonstad (Arlington, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts); Jacob Bernstein (Cambridge, Massachusetts)
ABSTRACT	This invention may be implemented as a microstructure probe for delivering light of variable color and/or power, via a set of integrated lightguides, from an optical source (or set of sources) to regions spatially arranged 3-dimensionally, with a length scale of microns to millimeters. In exemplary embodiments of this invention, a microstructure probe comprises many lightguides and is adapted to be inserted into neural or other tissue. The lightguides run in parallel along at least a portion of the axis of the probe. The probe may deliver light to many points along the axis of insertion of the probe. This invention may be implemented as an array of two or more such probes (each of which comprises multiple lightguides). This array may be used to deliver light to neural tissue in a complex 3D pattern.
FILED	Monday, July 26, 2010
APPL NO	12/843587
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/89
VIEW PATENT	@ USPTO: Full Text PDF

08545692 — Apparatus and method for electrochemical modification of concentrations of liquid streams

US 08545692	James et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Patrick Ismail James (Madison, Wisconsin); George Stejic (Arlington, Virginia)
ASSIGNEE(S)
INVENTOR(S)	Patrick Ismail James (Madison, Wisconsin); George Stejic (Arlington, Virginia)
ABSTRACT	An apparatus and a method for electrochemical modification of liquid streams using at least one anode and cathode assemblies arranged to contain liquid electrolytes anolyte and catholyte, a plurality of electrically conducting anode and cathode particulates forming anode and cathode particulate beds, and current feeder and current collector devices in contact with the particulate bed, where the anode particulates and cathode particulates are in motion substantially independent of bulk electrolytes flow.
FILED	Friday, May 27, 2011
APPL NO	13/117769
ART UNIT	1756 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/753
VIEW PATENT	@ USPTO: Full Text PDF

08545773 — Versatile multichannel capillary biosensor system

US 08545773	Su et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Science Foundation (NSF)
APPLICANT(S)	Xiao-Li Su (Fayetteville, Arkansas); Zungzhong Ye (Hangzhou, China PRC); Qian Sun (Fayetteville, Arkansas); Yanbin Li (Fayetteville, Arkansas)
ASSIGNEE(S)	The Board of Trustees of the University of Arkansas (Little Rock, Arkansas); BioDetection Instruments, LLC (Fayetteville, Arkansas)
INVENTOR(S)	Xiao-Li Su (Fayetteville, Arkansas); Zungzhong Ye (Hangzhou, China PRC); Qian Sun (Fayetteville, Arkansas); Yanbin Li (Fayetteville, Arkansas)
ABSTRACT	The multichannel capillary biosensor system includes a selecting valve system for selection of the sample or a reagent. The selecting valve system is connected to a second valve system accommodating a sensing channel and a first bypass channel. The second valve system is connected to a directing valve system having at least two positions, with a first position being connected to a second bypass channel and a second position being connected to a detector for detecting the analyte. The device has a pump connected at one end to the second bypass channel and the detector and at a second end to a waste vessel. The device also has a control system for controlling the device. The analyte can be selected from the group of microorganisms, macromolecules, and small molecules.
FILED	Thursday, July 24, 2008
APPL NO	12/670467
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/537
VIEW PATENT	@ USPTO: Full Text PDF

08545812 — Transport agents for crossing the blood-brain barrier and into brain cancer cells and methods of use thereof

US 08545812	Hong et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Chang Soo Hong (Chicago, Illinois); Tohru Yamada (Oak Park, Illinois); Arsenio M. Fialho (Lisbon, Portugal); Tapas K. Das Gupta (River Forest, Illinois); Ananda M. Chakrabarty (Villa Park, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Chang Soo Hong (Chicago, Illinois); Tohru Yamada (Oak Park, Illinois); Arsenio M. Fialho (Lisbon, Portugal); Tapas K. Das Gupta (River Forest, Illinois); Ananda M. Chakrabarty (Villa Park, Illinois)
ABSTRACT	The present invention discloses methods and materials for delivering a cargo compound into a brain cancer cell and/or across the blood-brain barrier. Delivery of the cargo compound is accomplished by the use of protein transport peptides derived from Neisseria outer membrane proteins, such as Laz. The invention also provides synthetic transit peptides comprised of the pentapeptide AAEAP. The invention further discloses methods for treating cancer, and specifically brain cancer, as well as other brain-related conditions. Further, the invention provides methods of imaging and diagnosing cancer, particular brain cancer.
FILED	Friday, May 25, 2012
APPL NO	13/481018
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/9.200
VIEW PATENT	@ USPTO: Full Text PDF

08545813 — Pre-templated macromolecular architectures with multiple Gd(III) complexes and methods of use as MRI contrast agents

US 08545813	Song et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Ying Song (Wilmette, Illinois); Thomas J. Meade (Wilmette, Illinois); Ellen Kohlmeir (Naperville, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Ying Song (Wilmette, Illinois); Thomas J. Meade (Wilmette, Illinois); Ellen Kohlmeir (Naperville, Illinois)
ABSTRACT	The present invention relates to contrast agents for MRI and related methods of use.
FILED	Monday, January 26, 2009
APPL NO	12/359914
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/9.300
VIEW PATENT	@ USPTO: Full Text PDF

08545814 — Non-invasive localization of a light-emitting conjugate in a mammal

US 08545814	Contag et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Redwood City, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Pamela R. Contag (San Jose, California); Christopher H. Contag (San Jose, California); David A. Benaron (Redwood City, California)
ABSTRACT	Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are methods for localizing and tracking the progression of disease or a pathogen within the animal, and for screening putative therapeutic compounds effective to inhibit the disease or pathogen.
FILED	Wednesday, June 13, 2007
APPL NO	11/818208
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/9.600
VIEW PATENT	@ USPTO: Full Text PDF

08545834 — G-substrate for the treatment and prevention of parkinson's disease

US 08545834	Isacson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Ole Isacson (Cambridge, Massachusetts); Chee-Yeun Chung (Cambridge, Massachusetts)
ASSIGNEE(S)	The McLean Hospital Corporation (Belmont, Massachusetts)
INVENTOR(S)	Ole Isacson (Cambridge, Massachusetts); Chee-Yeun Chung (Cambridge, Massachusetts)
ABSTRACT	The invention features methods and compositions for the treatment and prevention of Parkinson's Disease.
FILED	Tuesday, March 11, 2008
APPL NO	12/531044
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/93.200
VIEW PATENT	@ USPTO: Full Text PDF

08545841 — Methods and compositions for the treatment of cancers and pathogenic infections

US 08545841	Dunn et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	William A. Dunn (Gainesville, Florida); Debra E. Akin (Micanopy, Florida); Ann Progulske-Fox (Gainesville, Florida); David A. Ostrov (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	William A. Dunn (Gainesville, Florida); Debra E. Akin (Micanopy, Florida); Ann Progulske-Fox (Gainesville, Florida); David A. Ostrov (Gainesville, Florida)
ABSTRACT	The subject application provides small compounds that are able to suppress autophagy in various cells. These compounds are useful in augmenting the existing treatments of various cancers and microbial/parasitic infections. Thus, the subject application also provides methods of treating various types of cancers and microbial/parasitic infections. Also provided by the subject application are methods of suppressing the expansion of autophagosomes within cells or individuals and inhibiting the lipidation of autophagy-related protein 8 (Atg8).
FILED	Monday, January 05, 2009
APPL NO	12/811646
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/133.100
VIEW PATENT	@ USPTO: Full Text PDF

08545888 — Tendon stem cells

US 08545888	Young et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Marian F. Young (Silver Spring, Maryland); Yanming Bi (Boyds, Maryland); Songtao Shi (Irvine, California)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Marian F. Young (Silver Spring, Maryland); Yanming Bi (Boyds, Maryland); Songtao Shi (Irvine, California)
ABSTRACT	The invention relates to tendon stem cell useful for treating a variety of diseases and conditions, including tendon repair and attachment of tendon to bone. The invention is also directed to treatment and/or inhibition of bone formation by use of biglycan and/or fibromodulin.
FILED	Friday, June 13, 2008
APPL NO	12/663663
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/484
VIEW PATENT	@ USPTO: Full Text PDF

08546074 — Sir2 activity

US 08546074	Guarente et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Leonard P. Guarente (Newton, Massachusetts); Homayoun Vaziri (Montreal, Canada); Shin-Ichiro Imai (St. Louis, Missouri)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S)	Leonard P. Guarente (Newton, Massachusetts); Homayoun Vaziri (Montreal, Canada); Shin-Ichiro Imai (St. Louis, Missouri)
ABSTRACT	Methods for screening a compound, by providing a test mixture comprising a transcription factor, Sir2, and a Sir2 cofactor with the compound, and evaluating an activity of a component of the test mixture in the presence of the compound are described.
FILED	Thursday, June 14, 2012
APPL NO	13/523412
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

08546082 — Methods for identification of sepsis-causing bacteria

US 08546082	Hall et al.
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC)
APPLICANT(S)	Thomas A. Hall (Oceanside, California); Rangarajan Sampath (San Diego, California); Vanessa Harpin (San Diego, California); Steven A. Hofstadler (Vista, California); Yun Jiang (Carlsbad, California)
ASSIGNEE(S)	Ibis Biosciences, Inc. (Carlsbad, California)
INVENTOR(S)	Thomas A. Hall (Oceanside, California); Rangarajan Sampath (San Diego, California); Vanessa Harpin (San Diego, California); Steven A. Hofstadler (Vista, California); Yun Jiang (Carlsbad, California)
ABSTRACT	The present invention provides compositions, kits and methods for rapid identification and quantification of sepsis-causing bacteria by molecular mass and base composition analysis.
FILED	Friday, May 25, 2007
APPL NO	11/754182
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.120
VIEW PATENT	@ USPTO: Full Text PDF

08546083 — Molecular accessibility assay

US 08546083	Blaisdell
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Jeffrey O. Blaisdell (Colchester, Vermont)
ASSIGNEE(S)	University of Vermont (Burlington, Vermont); The University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S)	Jeffrey O. Blaisdell (Colchester, Vermont)
ABSTRACT	Methods and compositions are provided for determining polypeptide-nucleic acid interactions.
FILED	Friday, January 18, 2008
APPL NO	12/449042
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.120
VIEW PATENT	@ USPTO: Full Text PDF

08546088 — Porphyrinic compounds for use in flow cytometry

US 08546088	Lindsey
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Jonathan S. Lindsey (Raleigh, North Carolina)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina)
INVENTOR(S)	Jonathan S. Lindsey (Raleigh, North Carolina)
ABSTRACT	The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The method comprises utilizing as the detectable luminescent compound a compound comprising a porphyrinic macrocycle such as a porphyrin, chlorin, bacteriochlorin, or isobacteriochlorin. In particular embodiments, the detectable luminescent compound comprises a compound of the formula A-A′-Z-B′-B, wherein: A is a targeting group or member of a specific binding pair that specifically binds the detectable luminescent compound to the target compound, cell or particle; A′ is a linker group or covalent bond; B′ is a linker group or covalent bond; B is a water-soluble group; and Z is the porphyrinic macrocycle.
FILED	Monday, April 30, 2012
APPL NO	13/459464
ART UNIT	1623 — Organic Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.200
VIEW PATENT	@ USPTO: Full Text PDF

08546090 — SIRT4 activities

US 08546090	Haigis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Aging (NIA)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Instittue of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Marcia C. Haigis (Stoneham, Massachusetts); Leonard P. Guarente (Newton, Massachusetts)
ABSTRACT	Methods of modulating insulin secretion and treating metabolic disorders by modulating the expression or activity of Sirt4 are provided.
FILED	Friday, October 05, 2012
APPL NO	13/646148
ART UNIT	1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.210
VIEW PATENT	@ USPTO: Full Text PDF

08546091 — AKT phosphorylation at Ser473 as an indicator for taxane-based chemotherapy

US 08546091	Yang et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Sherry X. Yang (Ellicott City, Maryland); Sandra M. Swain (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Sherry X. Yang (Ellicott City, Maryland); Sandra M. Swain (Bethesda, Maryland)
ABSTRACT	Methods for determining whether a cancer patient is likely to benefit from treatment with a taxane compound based on Akt-Ser473 phosphorylation status are provided, together with kits for determining Akt-Ser473 phosphorylation status and methods for improving treatment of a cancer patient that include obtaining a determination of the Akt-Ser473 phosphorylation status of the cancer.
FILED	Friday, May 21, 2010
APPL NO	13/322140
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.230
VIEW PATENT	@ USPTO: Full Text PDF

08546095 — Methods for determination of calcineurin activity and uses in predicting therapeutic outcomes

US 08546095	Tumlin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	James Tumlin (Signal Mountain, Tennessee); Allan D. Kirk (Atlanta, Georgia); Brian R. Roberts (Sandy Springs, Georgia); Jennifer Gooch (Lilburn, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia)
INVENTOR(S)	James Tumlin (Signal Mountain, Tennessee); Allan D. Kirk (Atlanta, Georgia); Brian R. Roberts (Sandy Springs, Georgia); Jennifer Gooch (Lilburn, Georgia)
ABSTRACT	The methods of the disclosure provide fluorescence-based assays for calcineurin activity, especially in isolated T cells. The methods include the stimulation of the T cells with agents that specifically target the TCR with or without influencing co-stimulatory pathways. One TCR agonist is monoclonal antibodies specific for CD3, which more precisely distinguish the inducible activity of calcineurin than does an alternative method targeting the T cell receptor (CD3) combined with CD28 costimulation. This method more accurately distinguishes between the measured level of calcineurin activity of T cells from immunosuppressed transplant recipients and normal individuals, and thus has improved diagnostic accuracy with respect to the response of an individual to immunosuppressant therapy following an organ transplant.
FILED	Wednesday, January 20, 2010
APPL NO	12/690146
ART UNIT	1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.720
VIEW PATENT	@ USPTO: Full Text PDF

08546105 — Engineering intracellular sialylation pathways

US 08546105	Jarvis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF)
APPLICANT(S)	Donald Jarvis (Laramie, Wyoming); Michael J. Betenbaugh (Baltimore, Maryland); Shawn Lawrence (Valley Cottage, New York); Yuan C. Lee (Timonium, Maryland); Timothy A. Coleman (Derwood, Maryland)
ASSIGNEE(S)	The University of Wyoming (Laramie, Wyoming); The John Hopkins University (Baltimore, Maryland); Human Genome Sciences, Inc. (Rockville, Maryland)
INVENTOR(S)	Donald Jarvis (Laramie, Wyoming); Michael J. Betenbaugh (Baltimore, Maryland); Shawn Lawrence (Valley Cottage, New York); Yuan C. Lee (Timonium, Maryland); Timothy A. Coleman (Derwood, Maryland)
ABSTRACT	Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins.
FILED	Monday, August 09, 2010
APPL NO	12/806292
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/69.100
VIEW PATENT	@ USPTO: Full Text PDF

08546135 — In vivo genome-wide mutagenesis

US 08546135	Wu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Sen Wu (Salt Lake City, Utah); Mario R. Capecchi (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Sen Wu (Salt Lake City, Utah); Mario R. Capecchi (Salt Lake City, Utah)
ABSTRACT	Disclosed herein are compositions and methods for deleting or duplicating DNA in a mammalian genome. Also disclosed are compositions and methods for generating a random genome-wide chromosome rearrangement. Also disclosed are compositions and methods for streamlined construction of gene targeting vectors.
FILED	Friday, February 08, 2008
APPL NO	12/522075
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/320.100
VIEW PATENT	@ USPTO: Full Text PDF

08546137 — Inhibition of dendritic cell-driven regulatory T cell activation and potentiation of tumor antigen-specific T cell responses by interleukin-15 and MAP kinase inhibitor

US 08546137	Cannon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Martin J. Cannon (Little Rock, Arkansas); Kellie L. Kozak (Galveston, Texas); Timothy J. O'Brien (Little Rock, Arkansas)
ASSIGNEE(S)	The Board of Trustees of the University of Arkansas (Little Rock, Arkansas); National Institutes of Health, US Dept. of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Martin J. Cannon (Little Rock, Arkansas); Kellie L. Kozak (Galveston, Texas); Timothy J. O'Brien (Little Rock, Arkansas)
ABSTRACT	The invention involves the discovery that if dendritic cells loaded with a tumor antigen are cultured in interleukin-15 (IL-15), or if T cells activated by the dendritic cells are cultured in IL-15, Treg activity that is specific for the tumor antigen is reduced. This reduction in Treg activity results in an increase in anti-tumor immune response. Another embodiment of the invention involves the discovery that incubating dendritic cells with a MAP kinase inhibitor in combination with IL-15 gives synergistic benefits when the dendritic cells are used to activate T cells. Dendritic cell and T cell compositions incubated with IL-15 or a MAP kinase inhibitor are provided.
FILED	Saturday, September 27, 2008
APPL NO	12/286122
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/372
VIEW PATENT	@ USPTO: Full Text PDF

08546322 — Inhibitors of intracellular urokinase plasminogen activator and methods of use thereof

US 08546322	Gorin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Fredric A. Gorin (Davis, California); Michael H. Nantz (Louisville, Kentucky)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Fredric A. Gorin (Davis, California); Michael H. Nantz (Louisville, Kentucky)
ABSTRACT	The present invention provides compositions comprising amiloride amino acid and peptide conjugates. Efficient methods are also provided for administering the compositions for treating cancer and for delivering an amiloride conjugate into cancer cells in a subject in need thereof.
FILED	Friday, August 01, 2008
APPL NO	12/671824
ART UNIT	1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/1.300
VIEW PATENT	@ USPTO: Full Text PDF

08546324 — Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling

US 08546324	Arditi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Moshe Arditi (Encino, California); Pearl Gray (Los Angeles, California)
ASSIGNEE(S)	Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S)	Moshe Arditi (Encino, California); Pearl Gray (Los Angeles, California)
ABSTRACT	The present invention is based on a novel, alternatively spliced human isoform of MD-2 (MD-2s). In addition, the present invention relates to modified MD-2 proteins, wherein one or more tyrosine residues have been mutated to phenylalanine. In various embodiments, the invention relates to methods and kits for preventing, reducing the likelihood of developing and/or treating various conditions using MD-2s. The invention also describes methods of determining the risk of a subject to various conditions.
FILED	Friday, March 18, 2011
APPL NO	13/051390
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/2.100
VIEW PATENT	@ USPTO: Full Text PDF

08546345 — Compositions and methods for siRNA inhibition of angiogenesis

US 08546345	Tolentino et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Michael J. Tolentino (Villanova, Pennsylvania); Samuel Jotham Reich (Bala Cynwyd, Pennsylvania)
ASSIGNEE(S)	The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S)	Michael J. Tolentino (Villanova, Pennsylvania); Samuel Jotham Reich (Bala Cynwyd, Pennsylvania)
ABSTRACT	RNA interference using small interfering RNAs which are specific for the vascular endothelial growth factor (VEGF) gene and the VEGF receptor genes Flt-1 and Flk-1/KDR inhibit expression of these genes. Diseases which involve angiogenesis stimulated by overexpression of VEGF, such as diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering the small interfering RNAs.
FILED	Thursday, June 08, 2006
APPL NO	11/422982
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44.A00
VIEW PATENT	@ USPTO: Full Text PDF

08546348 — Upregulation of opioid receptors for management

US 08546348	Huang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Li-Yen Mae Huang (Galveston, Texas); Yanping Gu (League City, Texas)
ASSIGNEE(S)	The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	Li-Yen Mae Huang (Galveston, Texas); Yanping Gu (League City, Texas)
ABSTRACT	Disclosed are methods for treating pain in a subject. The method includes upregulating expression of opioid receptors in the subject's dorsal root ganglion or trigeminal neurons. Also disclosed are methods of treating neuropathic and/or chronic pain in a subject. The method includes upregulating expression of μ-opioid or δ-opioid receptors in the subject's dorsal root ganglion or trigeminal neurons.
FILED	Monday, October 04, 2010
APPL NO	12/924738
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44.R00
VIEW PATENT	@ USPTO: Full Text PDF

08546397 — DNA methylation inhibitors

US 08546397	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Ching-Shih Chen (Upper Arlington, Ohio); Arthur Y. Shaw (Tucson, Arizona); Yu-Wei Leu (Chia-Yi, Taiwan); Shu-Huei Hsiao (Chia-Yi, Taiwan)
ASSIGNEE(S)	The Ohio State University Research Foundation (Columbus, Ohio)
INVENTOR(S)	Ching-Shih Chen (Upper Arlington, Ohio); Arthur Y. Shaw (Tucson, Arizona); Yu-Wei Leu (Chia-Yi, Taiwan); Shu-Huei Hsiao (Chia-Yi, Taiwan)
ABSTRACT	A number of DNA methylation inhibitors are described. The DNA methylation inhibitors were identified using a two-component enhanced green fluorescent protein reporter system to screen a compound library containing procainamide derivatives. The DNA methylation inhibitors can be used for cancer therapy and prevention.
FILED	Monday, December 19, 2011
APPL NO	13/329593
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/252.130
VIEW PATENT	@ USPTO: Full Text PDF

08546408 — Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation

US 08546408	Krasinski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Antoni Krasinski (Mountain View, California); Sreenivas Punna (Sunnyvale, California); Solomon Ungashe (Fremont, California); Qiang Wang (Union City, California); Yibin Zeng (San Mateo, California)
ASSIGNEE(S)	Chemocentryx, Inc. (Mountain View, California)
INVENTOR(S)	Antoni Krasinski (Mountain View, California); Sreenivas Punna (Sunnyvale, California); Solomon Ungashe (Fremont, California); Qiang Wang (Union City, California); Yibin Zeng (San Mateo, California)
ABSTRACT	Fused heteroaryl pyridyl benzenesulfonamides are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
FILED	Wednesday, December 22, 2010
APPL NO	12/976768
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/265.100
VIEW PATENT	@ USPTO: Full Text PDF

08546419 — Dual phase drug release system

US 08546419	Papisov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Mikhail I. Papisov (Winchester, Massachusetts); Alexander Yurkovetskiy (Littleton, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Mikhail I. Papisov (Winchester, Massachusetts); Alexander Yurkovetskiy (Littleton, Massachusetts)
ABSTRACT	The present invention relates to conjugate comprising a carrier substituted with one or more occurrences of a moiety having the structure: wherein each occurrence of M is independently a modifier having a molecular weight ≦10 kDa; denotes direct of indirect attachment of M to linker L^M; and each occurrence of L^Mis independently an optionally substituted succinamide-containing linker, whereby the modifier M is directly or indirectly attached to the succinamide linker through an amide bond, and the carrier is linked directly or indirectly to each occurrence of the succinamide linker through an ester bond. In another aspect, the invention provides compositions comprising the conjugates, methods for their preparation, and methods of use thereof in the treatment of various disorder, including, but not limited to cancer.
FILED	Thursday, July 19, 2012
APPL NO	13/553244
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/283
VIEW PATENT	@ USPTO: Full Text PDF

08546421 — Oncogenic-RAS-signal dependent lethal compounds

US 08546421	Stockwell et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Brent R. Stockwell (New York, New York); Wan Seok Yang (New York, New York); Rohitha Sriramaratnam (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Brent R. Stockwell (New York, New York); Wan Seok Yang (New York, New York); Rohitha Sriramaratnam (New York, New York)
ABSTRACT	Compounds with cancer cell specific lethality are provided. In particular, RAS-selective lethal compounds and compositions are provided. Also provided are methods of screening for such compounds and methods of treating a condition in a mammal, by administering to the mammal a therapeutically effective amount of such compounds or compositions.
FILED	Friday, August 21, 2009
APPL NO	12/583579
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/292
VIEW PATENT	@ USPTO: Full Text PDF

08546426 — N-aminotetrahydroisoquinolines as anti-cancer agents

US 08546426	Redda et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Kinfe Ken Redda (Tallahassee, Florida); Madhavi Gangapuram (Tallahassee, Florida)
ASSIGNEE(S)	Florida A and M University Board of Trustees (Tallahassee, Florida)
INVENTOR(S)	Kinfe Ken Redda (Tallahassee, Florida); Madhavi Gangapuram (Tallahassee, Florida)
ABSTRACT	The compounds herein disclosed are tetrahydroisoquinoline analogs that have modifications on the phenyl rings by introducing groups with various electronic properties. These derivatives of tetrahydroisoquinoline have been shown to have anti-proliferative activity against cells. In particular, the compounds have been found to be effective in inhibiting the proliferation of cancer cells, such as cancer cells that originated in breast tissue. Additionally, it has been shown that the novel compounds have IC₅₀values against the breast cancer cells that are 6-10-fold less than the IC₅₀of tamoxifen.
FILED	Wednesday, November 30, 2011
APPL NO	13/307701
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/310
VIEW PATENT	@ USPTO: Full Text PDF

08546441 — PDK-1/AKT signaling inhibitors

US 08546441	Chen
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Ching-Shih Chen (Upper Arlington, Ohio)
ASSIGNEE(S)	The Ohio State University Research Foundation (Columbus, Ohio)
INVENTOR(S)	Ching-Shih Chen (Upper Arlington, Ohio)
ABSTRACT	A new class of phosphoinositide-dependent kinase-1 (PDK-1) inhibitors of formula I: wherein X is selected from the group consisting of alkyl and haloalkyl; Ar is an aryl radical selected from the group consisting of phenyl, biphenyl, naphthyl, anthryl, phenanthryl, and fluorenyl; and wherein Ar is optionally substituted with one or more radicals selected from the group consisting of halo, C₁-C₄alkyl, C₁-C₄haloalkyl, azido, C₁-C₄azidoalkyl, aryl, alkylaryl, haloaryl, haloalkylaryl, and combinations thereof; and R is selected from the group consisting of nitrile, acetonitrile, ethylnitrile, propylnitrile, carboxamide, amidine, tetrazole, oxime, hydrazone, acetamidine, aminoacetamide, guanidine, and urea. Also provided are methods of using the compounds for the treatment and prevention of cancer in humans.
FILED	Tuesday, June 02, 2009
APPL NO	12/476772
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/406
VIEW PATENT	@ USPTO: Full Text PDF

08546500 — Complexes for use in metathesis reactions

US 08546500	Hoveyda et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Amir H. Hoveyda (Lincoln, Massachusetts); Richard R. Schrock (Winchester, Massachusetts); Simon J. Meek (Newtonville, Massachusetts); Steven J. Malcolmson (Brighton, Massachusetts); Elizabeth T. Kiesewetter (Brighton, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S)	Amir H. Hoveyda (Lincoln, Massachusetts); Richard R. Schrock (Winchester, Massachusetts); Simon J. Meek (Newtonville, Massachusetts); Steven J. Malcolmson (Brighton, Massachusetts); Elizabeth T. Kiesewetter (Brighton, Massachusetts)
ABSTRACT	The present invention relates generally to metal complexes, methods for preparation and uses of the same.
FILED	Friday, May 25, 2012
APPL NO	13/481157
ART UNIT	1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 526/170
VIEW PATENT	@ USPTO: Full Text PDF

08546524 — Smoothened polypeptides and methods of use

US 08546524	Tarasova et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Nadya Tarasova (Frederick, Maryland); Michael Dean (Frederick, Maryland); Hong Lou (Frederick, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Nadya Tarasova (Frederick, Maryland); Michael Dean (Frederick, Maryland); Hong Lou (Frederick, Maryland)
ABSTRACT	Disclosed is an isolated or purified polypeptide or peptidomimetic comprising an amino acid sequence of a portion of a Smoothened (SMO) protein, wherein the portion comprises an amino acid sequence of any of the intracellular loops of the SMO protein, a functional fragment thereof, or a functional variant of either the portion or the functional fragment, wherein the functional fragment comprises at least 7 contiguous amino acids of the intracellular loops, and wherein the functional fragment or functional variant inhibits proliferation of a diseased cell, or a fatty acid derivative thereof. Related conjugates, nucleic acids, recombinant expression vectors, host cells, and pharmaceutical compositions are further provided. Methods of inhibiting proliferation of a diseased cell, treating or preventing cancer, treating a neoplasm or psoriasis, and inhibiting the expression of genes involved in the Hedgehog signaling pathway, thereby inhibiting the Hedgehog signaling pathway, are furthermore provided by the invention.
FILED	Monday, May 14, 2012
APPL NO	13/470965
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300
VIEW PATENT	@ USPTO: Full Text PDF

08546531 — Methods and reagents for preparing multifunctional probes

US 08546531	Josephson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Lee Josephson (Reading, Massachusetts); Elisabeth Garanger (Bordeaux, France)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Lee Josephson (Reading, Massachusetts); Elisabeth Garanger (Bordeaux, France)
ABSTRACT	Multifunctional probes are synthesized in a single step using peptide scaffold-based multifunctional single-attachment-point reagents. To obtain multifunctional probes using the methods of the invention, a substrate (e.g., a nanoparticle, polymer, antibody, protein, low molecular weight compound, drug, etc.) is reacted with a multifunctional single-attachment-point (MSAP) reagent. The MSAP reagents can include three components: (i) a peptide scaffold, (ii) a single chemically reactive group on the peptide scaffold for reaction of the MSAP with a substrate having a complementary reactive group, and (iii) multiple functional groups on the peptide scaffold. The peptide scaffold can include any number of residues; however, for ease of synthesis and reproducibility in clinical trials, it is preferred to limit the residues in the peptide to 20 or less. The reagent can be prepared to yield a predetermined stoichiometric ratio of the functional groups on the scaffold such that the probe has a fixed stoichiometric ratio of the functional groups.
FILED	Wednesday, July 15, 2009
APPL NO	13/054364
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/333
VIEW PATENT	@ USPTO: Full Text PDF

08546536 — Genetically engineered G-alpha proteins and uses thereof

US 08546536	Lowery et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Robert G. Lowery (Belleville, Wisconsin); Thomas K. Zielinski (Fitchburg, Wisconsin)
ASSIGNEE(S)	Bellbrook Labs, LLC (Madison, Wisconsin)
INVENTOR(S)	Robert G. Lowery (Belleville, Wisconsin); Thomas K. Zielinski (Fitchburg, Wisconsin)
ABSTRACT	The present invention relates to novel engineered Ga proteins and assay methods of using such proteins to advance drug discovery. Engineered Ga proteins described by the invention contain alterations of at least one and preferably two or more amino acid residues that are highly conserved among all four subfamilies of Ga proteins. A preferred engineered protein disclosed here is a double mutant, Gαπ R178M A326S. This specific combination of mutations yields an unexpectedly amplified effect on Ga function both in terms of GTPase activity (GTP hydrolysis) and GDP dissociation. This synergistic effect may have a profound influence on the way GPCR signaling pathways are examined for the development of new pharmacotherapies, particularly in the field of central nervous system disorders such as Parkinson's disease.
FILED	Friday, August 28, 2009
APPL NO	13/060895
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350
VIEW PATENT	@ USPTO: Full Text PDF

08546538 — Lymphoid chemokines in the diagnosis, monitoring and treatment of inflammatory disease

US 08546538	Segal et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Benjamin M. Segal (Ann Arbor, Michigan); Ludmila Bagaeva (Fairport, New York)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Benjamin M. Segal (Ann Arbor, Michigan); Ludmila Bagaeva (Fairport, New York)
ABSTRACT	Experimental autoimmune encephalomyelitis (EAE) is a Th1-mediated autoimmune disease of the central nervous system that is widely used as an animal model of multiple sclerosis (MS). In this study it was demonstrate that CXCL13, a chemokine involved in the development of secondary lymphoid tissues, is expressed in CD11c+ myeloid cells that accumulate in EAE lesions. Blockade or deficiency of CXCL13 ameliorates clinical EAE, both during acute and relapsing stages. CXCL13 deficiency did not inhibit the priming or differentiation of autoimmune effector T-cells in the periphery, but appeared to exert its effects during the effector phase of pathogenesis. These findings indicate that reagents that antagonize or inhibit CXCL13 are useful for the treatment of neuroinflammatory diseases such as MS.
FILED	Wednesday, April 09, 2008
APPL NO	12/100196
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.100
VIEW PATENT	@ USPTO: Full Text PDF

08546553 — Prokaryotic RNAi-like system and methods of use

US 08546553	Terns et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Rebecca Terns (Athens, Georgia); Michael Terns (Athens, Georgia); Caryn Hale (Athens, Georgia)
ASSIGNEE(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S)	Rebecca Terns (Athens, Georgia); Michael Terns (Athens, Georgia); Caryn Hale (Athens, Georgia)
ABSTRACT	Provided herein are methods for inactivating a target polynucleotide. The methods use a psiRNA having a 5′ region and a 3′ region. The 5′ region includes, but is not limited to, 5 to 10 nucleotides chosen from a repeat from a CRISPR locus immediately upstream of a spacer. The 3′ region is substantially complementary to a portion of the target polynucleotide. The methods may be practiced in a prokaryotic microbe or in vitro. Also provided are polypeptides that have endonuclease activity in the presence of a psiRNA and a target polynucleotide, and methods for using the polypeptides.
FILED	Friday, July 24, 2009
APPL NO	13/055769
ART UNIT	1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

08546562 — Substituted porphyrins

US 08546562	Crapo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	James D. Crapo (Englewood, Colorado); Brian J. Day (Englewood, Colorado); Michael P. Trova (Schenectady, New York); Polvina Jolicia F. Gauuan (Albany, New York); Douglas B. Kitchen (Schenectady, New York); Irwin Fridovich (Durham, North Carolina); Ines Batinic-Haberle (Durham, North Carolina)
ASSIGNEE(S)
INVENTOR(S)	James D. Crapo (Englewood, Colorado); Brian J. Day (Englewood, Colorado); Michael P. Trova (Schenectady, New York); Polvina Jolicia F. Gauuan (Albany, New York); Douglas B. Kitchen (Schenectady, New York); Irwin Fridovich (Durham, North Carolina); Ines Batinic-Haberle (Durham, North Carolina)
ABSTRACT	The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
FILED	Thursday, April 26, 2012
APPL NO	13/457232
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Organic compounds 540/145
VIEW PATENT	@ USPTO: Full Text PDF

08546607 — Cross-coupling of phenolic derivatives

US 08546607	Garg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Neil K. Garg (Los Angeles, California); Kyle W. Quasdorf (Los Angeles, California); Xia Tian (Boston, Massachusetts)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Neil K. Garg (Los Angeles, California); Kyle W. Quasdorf (Los Angeles, California); Xia Tian (Boston, Massachusetts)
ABSTRACT	Embodiments of the invention provide methods and materials for chemical cross-coupling reactions that utilize unconventional phenol derivatives as cross-coupling partners. Embodiments of the invention can be used to synthesize a variety of useful organic compounds, for example the anti-inflammatory drug flurbiprofen.
FILED	Friday, September 24, 2010
APPL NO	12/889765
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Organic compounds 562/7
VIEW PATENT	@ USPTO: Full Text PDF

08547533 — Composite probes and use thereof in super resolution methods

US 08547533	Knutson et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Jay R. Knutson (Kensington, Maryland); Gary L. Griffiths (North Potomac, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Jay R. Knutson (Kensington, Maryland); Gary L. Griffiths (North Potomac, Maryland)
ABSTRACT	Composite probes for super resolution optical techniques using super resolution via transiently activated quenchers (STAQ) include a donor moiety and an acceptor moiety joined by a linker, wherein the acceptor moiety, when excited by incident radiation, is excited to a state which, for example, absorbs in the donor emission region, such that the acceptor moiety in its excited state quenches at least a portion of the donor moiety emission. Other transiently activated quenching mechanisms and moieties could accomplish the same task by reducing donor population. Also disclosed are methods for irradiating a selected region of a target material including the composite probe, wherein the composite probe enables improved resolution by point spread function modification and/or nanoscale chemical reactions.
FILED	Tuesday, December 28, 2010
APPL NO	13/519737
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Optics: Measuring and testing 356/16
VIEW PATENT	@ USPTO: Full Text PDF

08548178 — Comb sense microphone

US 08548178	Miles
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	Ronald Miles (Newark Valley, New York)
ASSIGNEE(S)	The Research Foundation of State University of New York (Binghamton, New York)
INVENTOR(S)	Ronald Miles (Newark Valley, New York)
ABSTRACT	A miniature microphone, comprising a diaphragm, supported for displacement in response to acoustic waves, from which a plurality of projections extend; a plurality of projections extending from a surface; a body, supporting the surface to maintain the plurality of projections from the diaphragm and the plurality of projections from the surface in close proximity; and an electromagnetic sensor adapted to sense an electromagnetic interaction between the plurality of projections from the diaphragm and the plurality of projections from the surface and produce an electrical signal in response thereto. The interaction may be detected substantially without inducing a force which tends to substantially displace the diaphragm, since the electrostatic force is substantially parallel to the diaphragm surface.
FILED	Tuesday, December 06, 2011
APPL NO	13/311935
ART UNIT	2656 — Digital Audio Data Processing
CURRENT CPC	Electrical audio signal processing systems and devices 381/174
VIEW PATENT	@ USPTO: Full Text PDF

08548597 — External coil assembly for implantable medical prostheses

US 08548597	Dai et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Rongqing Dai (Valencia, California); Dao Min Zhou (Saugus, California); Robert J. Greenberg (Los Angeles, California); John Gord (Venice, California)
ASSIGNEE(S)	Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S)	Rongqing Dai (Valencia, California); Dao Min Zhou (Saugus, California); Robert J. Greenberg (Los Angeles, California); John Gord (Venice, California)
ABSTRACT	Methods and devices for inductively coupled implants on the human or animal body are disclosed. An external coil assembly to be used with the implant has a transmitting coil and one or more receiving coils. The number of the receiving coils, their distance from the transmitting coil and their shape is chosen to reduce the influence of a noise signal received by the external coil assembly.
FILED	Friday, September 29, 2006
APPL NO	11/529809
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/60
VIEW PATENT	@ USPTO: Full Text PDF

08548759 — Methods, apparatus, or systems for characterizing physical property in non-biomaterial or bio-material

US 08548759	Walker et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	William F. Walker (Charlottesville, Virginia); Francesco Viola (Charlottesville, Virginia); F. William Mauldin (Charlottesville, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia); HemoSonics, LLC (Charlottesville, Virginia)
INVENTOR(S)	William F. Walker (Charlottesville, Virginia); Francesco Viola (Charlottesville, Virginia); F. William Mauldin (Charlottesville, Virginia)
ABSTRACT	Techniques (e.g., system, apparatus, method, machine-readable medium) can be configured for characterizing a rheological or other structural physical property of a sample of a substance. In an example, this can include acoustically bidirectionally deforming the portion of the sample over a deformation range about a neutral-deformation locus within the deformation range, measuring a deformation response of at least a portion of the sample to the insonification, and characterizing the physical property of the sample using the measured response of at least a portion of the sample to the insonification, even in the presence of a flowing substance.
FILED	Friday, November 05, 2010
APPL NO	12/940838
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/56
VIEW PATENT	@ USPTO: Full Text PDF

08548768 — System and method for evaluating and providing treatment to sports participants

US 08548768	Greenwald et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Richard M. Greenwald (Norwich, Vermont); Jeffrey J. Chu (Quechee, Vermont); David W. Bertoni (Beverly, Massachusetts); Thad M. Ide (Chicago, Illinois)
ASSIGNEE(S)	Riddell, Inc. (Rosemont, Illinois)
INVENTOR(S)	Richard M. Greenwald (Norwich, Vermont); Jeffrey J. Chu (Quechee, Vermont); David W. Bertoni (Beverly, Massachusetts); Thad M. Ide (Chicago, Illinois)
ABSTRACT	The invention relates to a system for monitoring a physiological parameter of players engaged in a sports activity and a method for evaluating and treating players when the parameter exceeds a predetermined level. The system measures, calculates and records the parameter and then alerts trained personnel to apply the method to evaluate and treat players. When the system is configured for use with football, hockey or lacrosse, the system generally includes reporting units, a sideline controller, a database, and a signaling device, such as a wireless personal digital assistant. The physiological parameter data measured and collected by the reporting units are processed by the sideline controller for meaningful analysis or use. When the physiological parameter(s) exceeds a predetermined threshold level the sideline controller generates an alert that is received by the signaling device, which is typically worn by sideline personnel, such as coaching staff or trainers. After an alert occurs, the method for evaluating and treating a player is initiated.
FILED	Monday, January 09, 2006
APPL NO	11/328445
ART UNIT	2857 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/141
VIEW PATENT	@ USPTO: Full Text PDF

08548786 — Neuronal avalanche assay

US 08548786	Plenz
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Dietmar Plenz (Chevy Chase, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Dietmar Plenz (Chevy Chase, Maryland)
ABSTRACT	Method and system for determining a cognitive enhancement and/or anti-epileptic effect comprising: detecting synchronized neuronal activity in neuronal tissue (601), monitoring spreading of the synchronized neuronal activity (602), determining a parameter (604, 605) indicative of the closeness of the synchronized neuronal activity to the critical state and comparing (613) the parameter to a predetermined value.
FILED	Monday, August 14, 2006
APPL NO	11/990419
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electric Digital Data Processing G06F 19/34 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

08544274 — Energy recovery system using an organic rankine cycle

US 08544274	Ernst
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Timothy C Ernst (Columbus, Indiana)
ASSIGNEE(S)	Cummins Intellectual Properties, Inc. (Minneapolis, Minnesota)
INVENTOR(S)	Timothy C Ernst (Columbus, Indiana)
ABSTRACT	A thermodynamic system for waste heat recovery, using an organic rankine cycle is provided which employs a single organic heat transferring fluid to recover heat energy from two waste heat streams having differing waste heat temperatures. Separate high and low temperature boilers provide high and low pressure vapor streams that are routed into an integrated turbine assembly having dual turbines mounted on a common shaft. Each turbine is appropriately sized for the pressure ratio of each stream.
FILED	Thursday, July 23, 2009
APPL NO	12/508190
ART UNIT	3748 — SELECT * FROM codes_techcenter;
CURRENT CPC	Power plants 060/651
VIEW PATENT	@ USPTO: Full Text PDF

08544295 — Methods of conveying fluids and methods of sublimating solid particles

US 08544295	Turner et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho)
ASSIGNEE(S)	Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S)	Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho)
ABSTRACT	A heat exchanger and associated methods for sublimating solid particles therein, for conveying fluids therethrough, or both. The heat exchanger includes a chamber and a porous member having a porous wall having pores in communication with the chamber and with an interior of the porous member. A first fluid is conveyed into the porous member while a second fluid is conveyed into the porous member through the porous wall. The second fluid may form a positive flow boundary layer along the porous wall to reduce or eliminate substantial contact between the first fluid and the interior of the porous wall. The combined first and second fluids are conveyed out of the porous member. Additionally, the first fluid and the second fluid may each be conveyed into the porous member at different temperatures and may exit the porous member at substantially the same temperature.
FILED	Friday, October 28, 2011
APPL NO	13/284737
ART UNIT	3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Refrigeration 062/614
VIEW PATENT	@ USPTO: Full Text PDF

08544297 — Apparatus and process to enhance the uniform formation of hollow glass microspheres

US 08544297	Schumacher
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM) Savannah River National Laboratory (SRNL) Federally Funded Research and Development Center (FFRDC) Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)	Ray F. Schumacher (Aiken, South Carolina)
ASSIGNEE(S)	Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S)	Ray F. Schumacher (Aiken, South Carolina)
ABSTRACT	A process and apparatus is provided for enhancing the formation of a uniform population of hollow glass microspheres. A burner head is used which directs incoming glass particles away from the cooler perimeter of the flame cone of the gas burner and distributes the glass particles in a uniform manner throughout the more evenly heated portions of the flame zone. As a result, as the glass particles are softened and expand by a released nucleating gas so as to form a hollow glass microsphere, the resulting hollow glass microspheres have a more uniform size and property distribution as a result of experiencing a more homogenous heat treatment process.
FILED	Monday, December 04, 2006
APPL NO	12/312974
ART UNIT	1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Glass manufacturing 065/21.400
VIEW PATENT	@ USPTO: Full Text PDF

08544714 — Certification of a weld produced by friction stir welding

US 08544714	Obaditch et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S)	Fluor Technologies Corporation (Aliso Viejo, California)
ASSIGNEE(S)	Fluor Technologies Corporation (Aliso Viejo, California)
INVENTOR(S)	Chris Obaditch (Corona Del Mar, California); Glenn J. Grant (Benton City, Washington)
ABSTRACT	Methods, devices, and systems for providing certification of friction stir welds are disclosed. A sensor is used to collect information related to a friction stir weld. Data from the sensor is compared to threshold values provided by an extrinsic standard setting organizations using a certification engine. The certification engine subsequently produces a report on the certification status of the weld.
FILED	Thursday, November 15, 2012
APPL NO	13/677586
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Metal fusion bonding 228/102
VIEW PATENT	@ USPTO: Full Text PDF

08545633 — Method for producing ethanol and co-products from cellulosic biomass

US 08545633	Nguyen
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Quang A. Nguyen (Chesterfield, Missouri)
ASSIGNEE(S)	Abengoa Bioenergy New Technologies, Inc. (Chesterfield, Mississippi)
INVENTOR(S)	Quang A. Nguyen (Chesterfield, Missouri)
ABSTRACT	The present invention generally relates to processes for production of ethanol from cellulosic biomass. The present invention also relates to production of various co-products of preparation of ethanol from cellulosic biomass. The present invention further relates to improvements in one or more aspects of preparation of ethanol from cellulosic biomass including, for example, improved methods for cleaning biomass feedstocks, improved acid impregnation, and improved steam treatment, or “steam explosion.”
FILED	Monday, September 19, 2011
APPL NO	13/236272
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Sugar, starch, and carbohydrates 127/34
VIEW PATENT	@ USPTO: Full Text PDF

08545657 — Methods for tape fabrication of continuous filament composite parts and articles of manufacture thereof

US 08545657	Weisberg
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Andrew H. Weisberg (San Francisco, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Andrew H. Weisberg (San Francisco, California)
ABSTRACT	A method for forming a composite structure according to one embodiment includes forming a first ply; and forming a second ply above the first ply. Forming each ply comprises: applying a bonding material to a tape, the tape comprising a fiber and a matrix, wherein the bonding material has a curing time of less than about 1 second; and adding the tape to a substrate for forming adjacent tape winds having about a constant distance therebetween. Additional systems, methods and articles of manufacture are also presented.
FILED	Friday, October 30, 2009
APPL NO	12/610050
ART UNIT	1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Adhesive bonding and miscellaneous chemical manufacture 156/184
VIEW PATENT	@ USPTO: Full Text PDF

08545820 — Use of titanium-based materials as bactericides

US 08545820	Hobbs et al.
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM) Savannah River National Laboratory (SRNL) Federally Funded Research and Development Center (FFRDC) Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)	David T. Hobbs (North Augusta, South Carolina); Mark C. Elvington (Aiken, South Carolina); John Wataha (Edmonds, Washington); Whasun O. Chung (Lake Forest Park, Washington); R. Bruce Rutherford (Seattle, Washington); Daniel C. Chan (Seattle, Washington)
ASSIGNEE(S)	Savannah River Nuclear Solutions, LLC (Aiken, South Carolina); University of Washington Center for Commercialization (Seattle, Washington)
INVENTOR(S)	David T. Hobbs (North Augusta, South Carolina); Mark C. Elvington (Aiken, South Carolina); John Wataha (Edmonds, Washington); Whasun O. Chung (Lake Forest Park, Washington); R. Bruce Rutherford (Seattle, Washington); Daniel C. Chan (Seattle, Washington)
ABSTRACT	Compositions containing metal ions bound into a titanate are described which have demonstrated an ability to suppress bacterial growth of a number of organisms associated with periodontal disease and caries.
FILED	Thursday, July 14, 2011
APPL NO	13/135745
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/49
VIEW PATENT	@ USPTO: Full Text PDF

08545995 — Systems having optical absorption layer for mid and long wave infrared and methods for making the same

US 08545995	Kuzmenko
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Paul J. Kuzmenko (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore national Security, LLC. (Livermore, California)
INVENTOR(S)	Paul J. Kuzmenko (Livermore, California)
ABSTRACT	An optical system according to one embodiment includes a substrate; and an optical absorption layer coupled to the substrate, wherein the optical absorption layer comprises a layer of diamond-like carbon, wherein the optical absorption layer absorbs at least 50% of mid wave infrared light (3-5 μm wavelength) and at least 50% of long wave infrared light (8-13 μm wavelength). A method for applying an optical absorption layer to an optical system according to another embodiment includes depositing a layer of diamond-like carbon of an optical absorption layer above a substrate using plasma enhanced chemical vapor deposition, wherein the optical absorption layer absorbs at least 50% of mid wave infrared light (3-5 μm wavelength) and at least 50% of long wave infrared light (8-13 μm wavelength). Additional systems and methods are also presented.
FILED	Monday, December 14, 2009
APPL NO	12/637638
ART UNIT	2872 — Optics
CURRENT CPC	Stock material or miscellaneous articles 428/688
VIEW PATENT	@ USPTO: Full Text PDF

08546073 — Method and apparatus for enhanced detection of toxic agents

US 08546073	Greenbaum et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Elias Greenbaum (Knoxville, Tennessee); Miguel Rodriguez, Jr. (Oak Ridge, Tennessee); Jie Jayne Wu (Knoxville, Tennessee); Hairong Qi (Knoxville, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Elias Greenbaum (Knoxville, Tennessee); Miguel Rodriguez, Jr. (Oak Ridge, Tennessee); Jie Jayne Wu (Knoxville, Tennessee); Hairong Qi (Knoxville, Tennessee)
ABSTRACT	A biosensor based detection of toxins includes enhancing a fluorescence signal by concentrating a plurality of photosynthetic organisms in a fluid into a concentrated region using biased AC electro-osmosis. A measured photosynthetic activity of the photosynthetic organisms is obtained in the concentrated region, where chemical, biological or radiological agents reduce a nominal photosynthetic activity of the photosynthetic organisms. A presence of the chemical, biological and/or radiological agents or precursors thereof, is determined in the fluid based on the measured photosynthetic activity of the concentrated plurality of photosynthetic organisms. A lab-on-a-chip system is used for the concentrating step. The presence of agents is determined from feature vectors, obtained from processing a time dependent signal using amplitude statistics and/or time-frequency analysis, relative to a control signal. A linear discriminant method including support vector machine classification (SVM) is used to identify the agents.
FILED	Thursday, May 17, 2012
APPL NO	13/474183
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

08546106 — Methods of increasing secretion of polypeptides having biological activity

US 08546106	Merino
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Sandra Merino (West Sacramento, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Sandra Merino (West Sacramento, California)
ABSTRACT	The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.
FILED	Friday, July 20, 2007
APPL NO	11/781151
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/69.700
VIEW PATENT	@ USPTO: Full Text PDF

08546264 — Etching radical controlled gas chopped deep reactive ion etching

US 08546264	Olynick et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Deirdre Olynick (El Cerrito, California); Ivo Rangelow (Baunatal, Germany); Weilun Chao (El Cerrito, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Deirdre Olynick (El Cerrito, California); Ivo Rangelow (Baunatal, Germany); Weilun Chao (El Cerrito, California)
ABSTRACT	A method for silicon micromachining techniques based on high aspect ratio reactive ion etching with gas chopping has been developed capable of producing essentially scallop-free, smooth, sidewall surfaces. The method uses precisely controlled, alternated (or chopped) gas flow of the etching and deposition gas precursors to produce a controllable sidewall passivation capable of high anisotropy. The dynamic control of sidewall passivation is achieved by carefully controlling fluorine radical presence with moderator gasses, such as CH₄and controlling the passivation rate and stoichiometry using a CF₂source. In this manner, sidewall polymer deposition thicknesses are very well controlled, reducing sidewall ripples to very small levels. By combining inductively coupled plasmas with controlled fluorocarbon chemistry, good control of vertical structures with very low sidewall roughness may be produced. Results show silicon features with an aspect ratio of 20:1 for 10 nm features with applicability to nano-applications in the sub-50 nm regime. By comparison, previous traditional gas chopping techniques have produced rippled or scalloped sidewalls in a range of 50 to 100 nm roughness.
FILED	Friday, June 02, 2006
APPL NO	11/421958
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Semiconductor device manufacturing: Process 438/712
VIEW PATENT	@ USPTO: Full Text PDF

08546635 — Methods and apparatuses for preparing upgraded pyrolysis oil

US 08546635	Brandvold et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Timothy A. Brandvold (Arlington Heights, Illinois); Lance Awender Baird (Prospect Heights, Illinois); Stanley Joseph Frey (Palatine, Illinois)
ASSIGNEE(S)	UOP LLC (Des Plaines, Illinois)
INVENTOR(S)	Timothy A. Brandvold (Arlington Heights, Illinois); Lance Awender Baird (Prospect Heights, Illinois); Stanley Joseph Frey (Palatine, Illinois)
ABSTRACT	Methods and apparatuses for preparing upgraded pyrolysis oil are provided herein. In an embodiment, a method of preparing upgraded pyrolysis oil includes providing a biomass-derived pyrolysis oil stream having an original oxygen content. The biomass-derived pyrolysis oil stream is hydrodeoxygenated under catalysis in the presence of hydrogen to form a hydrodeoxygenated pyrolysis oil stream comprising a cyclic paraffin component. At least a portion of the hydrodeoxygenated pyrolysis oil stream is dehydrogenated under catalysis to form the upgraded pyrolysis oil.
FILED	Wednesday, April 04, 2012
APPL NO	13/439708
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry of hydrocarbon compounds 585/639
VIEW PATENT	@ USPTO: Full Text PDF

08547006 — Electron gun for a multiple beam klystron with magnetic compression of the electron beams

US 08547006	Ives et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	R. Lawrence Ives (San Mateo, California); Hien T. Tran (Cary, North Carolina); Thuc Bui (Mountain View, California); Adam Attarian (Raleigh, North Carolina); William Tallis (Cary, North Carolina); John David (Wooster, Ohio); Virginia Forstall (Fairfax, Virginia); Cynthia Andujar (Cary, North Carolina); Noah T. Blach (Chapel Hill, North Carolina); David B. Brown (Raleigh, North Carolina); Sean E. Gadson (Columbia, South Carolina); Erin M. Kiley (Loudon, New Hampshire); Michael Read (Plainfield, Vermont)
ASSIGNEE(S)	Calabazas Creek Research, Inc. (San Mateo, California)
INVENTOR(S)	R. Lawrence Ives (San Mateo, California); Hien T. Tran (Cary, North Carolina); Thuc Bui (Mountain View, California); Adam Attarian (Raleigh, North Carolina); William Tallis (Cary, North Carolina); John David (Wooster, Ohio); Virginia Forstall (Fairfax, Virginia); Cynthia Andujar (Cary, North Carolina); Noah T. Blach (Chapel Hill, North Carolina); David B. Brown (Raleigh, North Carolina); Sean E. Gadson (Columbia, South Carolina); Erin M. Kiley (Loudon, New Hampshire); Michael Read (Plainfield, Vermont)
ABSTRACT	A multi-beam electron gun provides a plurality N of cathode assemblies comprising a cathode, anode, and focus electrode, each cathode assembly having a local cathode axis and also a central cathode point defined by the intersection of the local cathode axis with the emitting surface of the cathode. Each cathode is arranged with its central point positioned in a plane orthogonal to a device central axis, with each cathode central point an equal distance from the device axis and with an included angle of 360/N between each cathode central point. The local axis of each cathode has a cathode divergence angle with respect to the central axis which is set such that the diverging magnetic field from a solenoidal coil is less than 5 degrees with respect to the projection of the local cathode axis onto a cathode reference plane formed by the device axis and the central cathode point, and the local axis of each cathode is also set such that the angle formed between the cathode reference plane and the local cathode axis results in minimum spiraling in the path of the electron beams in a homogenous magnetic field region of the solenoidal field generator.
FILED	Friday, February 12, 2010
APPL NO	12/705160
ART UNIT	2889 — Optics
CURRENT CPC	Electric lamp and discharge devices 313/414
VIEW PATENT	@ USPTO: Full Text PDF

08547095 — Detection of magnetic resonance signals using a magnetoresistive sensor

US 08547095	Budker et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Dmitry Budker (El Cerrito, California); Alexander Pines (Berkeley, California); Shoujun Xu (Houston, Texas); Christian Hilty (College Station, Texas); Micah P. Ledbetter (Oakland, California); Louis S. Bouchard (Los Angeles, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Dmitry Budker (El Cerrito, California); Alexander Pines (Berkeley, California); Shoujun Xu (Houston, Texas); Christian Hilty (College Station, Texas); Micah P. Ledbetter (Oakland, California); Louis S. Bouchard (Los Angeles, California)
ABSTRACT	A method and apparatus are described wherein a micro sample of a fluidic material may be assayed without sample contamination using NMR techniques, in combination with magnetoresistive sensors. The fluidic material to be assayed is first subject to pre-polarization, in one embodiment, by passage through a magnetic field. The magnetization of the fluidic material is then subject to an encoding process, in one embodiment an rf-induced inversion by passage through an adiabatic fast-passage module. Thereafter, the changes in magnetization are detected by a pair of solid-state magnetoresistive sensors arranged in gradiometer mode. Miniaturization is afforded by the close spacing of the various modules.
FILED	Friday, April 02, 2010
APPL NO	12/753306
ART UNIT	2858 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/307
VIEW PATENT	@ USPTO: Full Text PDF

08547187 — Printed circuit board impedance matching step for microwave (millimeter wave) devices

US 08547187	Pao et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Hsueh-Yuan Pao (San Jose, California); Jerardo Aguirre (San Diego, California); Paul Sargis (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC. (Livermore, California); Kyocera America, Inc. (San Diego, California)
INVENTOR(S)	Hsueh-Yuan Pao (San Jose, California); Jerardo Aguirre (San Diego, California); Paul Sargis (Livermore, California)
ABSTRACT	An impedance matching ground plane step, in conjunction with a quarter wave transformer section, in a printed circuit board provides a broadband microwave matching transition from board connectors or other elements that require thin substrates to thick substrate (>quarter wavelength) broadband microwave (millimeter wave) devices. A method of constructing microwave and other high frequency electrical circuits on a substrate of uniform thickness, where the circuit is formed of a plurality of interconnected elements of different impedances that individually require substrates of different thicknesses, by providing a substrate of uniform thickness that is a composite or multilayered substrate; and forming a pattern of intermediate ground planes or impedance matching steps interconnected by vias located under various parts of the circuit where components of different impedances are located so that each part of the circuit has a ground plane substrate thickness that is optimum while the entire circuit is formed on a substrate of uniform thickness.
FILED	Thursday, September 30, 2010
APPL NO	12/895347
ART UNIT	2817 — Semiconductors/Memory
CURRENT CPC	Wave transmission lines and networks 333/33
VIEW PATENT	@ USPTO: Full Text PDF

08547271 — Method and apparatus for low power analog-to-digital conversion

US 08547271	De Geronimo et al.
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	Gianluigi De Geronimo (Syosset, New York); Neena Nambiar (Ridge, New York)
ASSIGNEE(S)	Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S)	Gianluigi De Geronimo (Syosset, New York); Neena Nambiar (Ridge, New York)
ABSTRACT	A method and apparatus for analog-to-digital conversion. An Analog-to-Digital Converter (ADC) includes M ADC_j, j=1, 2, . . . , M. Each ADC_jcomprises a number of cells each of which comprises a first switch, a second switch, a current sink and an inverter. An inverter of a cell in an ADC_jchanges state in response to a current associate with an input signal of the ADC_jexceeding a threshold, thus switching on the next cell. Each ADC_jis enabled to perform analog-to-digital conversion on a residual current of a previous ADC_j-1after the previous ADC_j-1has completed its analog-to-digital conversion and has been disabled.
FILED	Thursday, May 17, 2012
APPL NO	13/474060
ART UNIT	2819 — Semiconductors/Memory
CURRENT CPC	Coded data generation or conversion 341/161
VIEW PATENT	@ USPTO: Full Text PDF

08547632 — Method and system for homogenizing diode laser pump arrays

US 08547632	Bayramian
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Andy J. Bayramian (Manteca, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Andy J. Bayramian (Manteca, California)
ABSTRACT	An optical amplifier system includes a diode pump array including a plurality of semiconductor diode laser bars disposed in an array configuration and characterized by a periodic distance between adjacent semiconductor diode laser bars. The periodic distance is measured in a first direction perpendicular to each of the plurality of semiconductor diode laser bars. The diode pump array provides a pump output propagating along an optical path and characterized by a first intensity profile measured as a function of the first direction and having a variation greater than 10%. The optical amplifier system also includes a diffractive optic disposed along the optical path. The diffractive optic includes a photo-thermo-refractive glass member. The optical amplifier system further includes an amplifier slab having an input face and position along the optical path and separated from the diffractive optic by a predetermined distance. A second intensity profile measured at the input face of the amplifier slab as a function of the first direction has a variation less than 10%.
FILED	Wednesday, August 19, 2009
APPL NO	12/544147
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Optical: Systems and elements 359/345
VIEW PATENT	@ USPTO: Full Text PDF

08547790 — Device and method for generating a beam of acoustic energy from a borehole, and applications thereof

US 08547790	Vu et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Cung Khac Vu (Houston, Texas); Dipen N. Sinha (Los Alamos, New Mexico); Cristian Pantea (Los Alamos, New Mexico); Kurt T. Nihei (Oakland, California); Denis P. Schmitt (Katy, Texas); Christopher Skelt (Houston, Texas)
ASSIGNEE(S)	Chevron U.S.A. Inc. (San Ramon, California); Los Alamos National Security LLC (Los Alamos, New Mexico)
INVENTOR(S)	Cung Khac Vu (Houston, Texas); Dipen N. Sinha (Los Alamos, New Mexico); Cristian Pantea (Los Alamos, New Mexico); Kurt T. Nihei (Oakland, California); Denis P. Schmitt (Katy, Texas); Christopher Skelt (Houston, Texas)
ABSTRACT	In some aspects of the invention, a method of generating a beam of acoustic energy in a borehole is disclosed. The method includes generating a first acoustic wave at a first frequency; generating a second acoustic wave at a second frequency different than the first frequency, wherein the first acoustic wave and second acoustic wave are generated by at least one transducer carried by a tool located within the borehole; transmitting the first and the second acoustic waves into an acoustically non-linear medium, wherein the composition of the non-linear medium produces a collimated beam by a non-linear mixing of the first and second acoustic waves, wherein the collimated beam has a frequency based upon a difference between the first frequency and the second frequency; and transmitting the collimated beam through a diverging acoustic lens to compensate for a refractive effect caused by the curvature of the borehole.
FILED	Thursday, June 03, 2010
APPL NO	12/793414
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/00 (20130101) Original (OR) Class G01V 1/006 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08547791 — Device and method for generating a beam of acoustic energy from a borehole, and applications thereof

US 08547791	Vu et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Cung Khac Vu (Houston, Texas); Dipen N. Sinha (Los Alamos, New Mexico); Cristian Pantea (Los Alamos, New Mexico); Kurt T. Nihei (Oakland, California); Denis P. Schmitt (Katy, Texas); Christopher Skelt (Houston, Texas)
ASSIGNEE(S)	Chevron U.S.A. Inc. (San Ramon, California); Los Alamos National Security LLC (Los Alamos, New Mexico)
INVENTOR(S)	Cung Khac Vu (Houston, Texas); Dipen N. Sinha (Los Alamos, New Mexico); Cristian Pantea (Los Alamos, New Mexico); Kurt T. Nihei (Oakland, California); Denis P. Schmitt (Katy, Texas); Christopher Skelt (Houston, Texas)
ABSTRACT	In some aspects of the invention, a method of generating a beam of acoustic energy in a borehole is disclosed. The method includes generating a first broad-band acoustic pulse at a first broad-band frequency range having a first central frequency and a first bandwidth spread; generating a second broad-band acoustic pulse at a second broad-band frequency range different than the first frequency range having a second central frequency and a second bandwidth spread, wherein the first acoustic pulse and second acoustic pulse are generated by at least one transducer arranged on a tool located within the borehole; and transmitting the first and the second broad-band acoustic pulses into an acoustically non-linear medium, wherein the composition of the non-linear medium produces a collimated pulse by a non-linear mixing of the first and second acoustic pulses, wherein the collimated pulse has a frequency equal to the difference in frequencies between the first central frequency and the second central frequency and a bandwidth spread equal to the sum of the first bandwidth spread and the second bandwidth spread.
FILED	Thursday, June 03, 2010
APPL NO	12/793420
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Communications, electrical: Acoustic wave systems and devices 367/32
VIEW PATENT	@ USPTO: Full Text PDF

08548636 — Engineered setpoints for autonomous distributed sensors and actuators

US 08548636	Edmunds
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Thomas A. Edmunds (Pleasanton, California)
ASSIGNEE(S)	Lawrence Livermore National Secuirty, LLC. (Livermore, California)
INVENTOR(S)	Thomas A. Edmunds (Pleasanton, California)
ABSTRACT	Loads on an electric power system are configured with under-frequency relays in which the frequency setpoints and delay times for reclosure are uniformly distributed. If demand exceeds supply in the system, frequency will decrease. The decrease in frequency will actuate relays and reduce load to the point where demand will meet the available supply. After its engineered delay time, each relay will attempt to close contact and reestablish the load.
FILED	Friday, September 25, 2009
APPL NO	12/566869
ART UNIT	2121 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Generic control systems or specific applications 7/295
VIEW PATENT	@ USPTO: Full Text PDF

08548745 — Visual-servoing optical microscopy

US 08548745	Callahan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Daniel E. Callahan (Martinez, California); Bahram Parvin (Herculez, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Daniel E. Callahan (Martinez, California); Bahram Parvin (Herculez, California)
ABSTRACT	The present invention provides methods and devices for the knowledge-based discovery and optimization of differences between cell types. In particular, the present invention provides visual servoing optical microscopy, as well as analysis methods. The present invention provides means for the close monitoring of hundreds of individual, living cells over time; quantification of dynamic physiological responses in multiple channels; real-time digital image segmentation and analysis; intelligent, repetitive computer-applied cell stress and cell stimulation; and the ability to return to the same field of cells for long-term studies and observation. The present invention further provides means to optimize culture conditions for specific subpopulations of cells.
FILED	Friday, May 13, 2011
APPL NO	13/107601
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

08548746 — Methods for monitoring multiple gene expression

US 08548746	Berka et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Randy Berka (Davis, California); Elena Bachkirova (Davis, California); Michael Rey (Davis, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Randy Berka (Davis, California); Elena Bachkirova (Davis, California); Michael Rey (Davis, California)
ABSTRACT	The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing Trichoderma reesei ESTs or SSH clones, or a combination thereof. The present invention also relates to computer readable media and substrates containing such array features for monitoring expression of a plurality of genes in filamentous fungal cells.
FILED	Wednesday, April 04, 2012
APPL NO	13/439547
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/19
VIEW PATENT	@ USPTO: Full Text PDF

08549196 — Hardware support for software controlled fast multiplexing of performance counters

US 08549196	Salapura et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Valentina Salapura (Yorktown Heights, New York); Robert W. Wisniewski (Yorktown Heights, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Valentina Salapura (Yorktown Heights, New York); Robert W. Wisniewski (Yorktown Heights, New York)
ABSTRACT	Performance counters may be operable to collect one or more counts of one or more selected activities, and registers may be operable to store a set of performance counter configurations. A state machine may be operable to automatically select a register from the registers for reconfiguring the one or more performance counters in response to receiving a first signal. The state machine may be further operable to reconfigure the one or more performance counters based on a configuration specified in the selected register. The state machine yet further may be operable to copy data in selected one or more of the performance counters to a memory location, or to copy data from the memory location to the counters, in response to receiving a second signal. The state machine may be operable to store or restore the counter values and state machine configuration in response to a context switch event.
FILED	Friday, August 03, 2012
APPL NO	13/566528
ART UNIT	2181 — Computer Architecture and I/O
CURRENT CPC	Electrical computers and digital data processing systems: Input/output 710/62
VIEW PATENT	@ USPTO: Full Text PDF

08549363 — Reliability and performance of a system-on-a-chip by predictive wear-out based activation of functional components

US 08549363	Cher et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Chen-Yong Cher (Port Chester, New York); Paul W. Coteus (Yorktown Heights, New York); Alan Gara (Mount Kisco, New York); Eren Kursun (Ossining, New York); David P. Paulsen (Dodge Center, Minnesota); Brian A. Schuelke (Rochester, Minnesota); John E. Sheets, II (Zumbrota, Minnesota); Shurong Tian (Mount Kisco, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Chen-Yong Cher (Port Chester, New York); Paul W. Coteus (Yorktown Heights, New York); Alan Gara (Mount Kisco, New York); Eren Kursun (Ossining, New York); David P. Paulsen (Dodge Center, Minnesota); Brian A. Schuelke (Rochester, Minnesota); John E. Sheets, II (Zumbrota, Minnesota); Shurong Tian (Mount Kisco, New York)
ABSTRACT	A processor-implemented method for determining aging of a processing unit in a processor the method comprising: calculating an effective aging profile for the processing unit wherein the effective aging profile quantifies the effects of aging on the processing unit; combining the effective aging profile with process variation data, actual workload data and operating conditions data for the processing unit; and determining aging through an aging sensor of the processing unit using the effective aging profile, the process variation data, the actual workload data, architectural characteristics and redundancy data, and the operating conditions data for the processing unit.
FILED	Friday, March 19, 2010
APPL NO	12/727967
ART UNIT	2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Error detection/correction and fault detection/recovery 714/47.300
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

08544280 — Continuous detonation wave engine with quenching structure

US 08544280	Lu et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Frank K. Lu (Arlington, Texas); Nathan L. Dunn (Arlington, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Frank K. Lu (Arlington, Texas); Nathan L. Dunn (Arlington, Texas)
ABSTRACT	A continuous detonation wave engine (CDWE) is disclosed. An example embodiment includes a generally annular combustion chamber dimensioned to allow a fuel mixture to detonate, a mixing chamber, and a fuel mixture channel that provides for fluid communication between the mixing chamber and the combustion chamber. At least part of the fuel mixture channel features a quenching structure dimensioned to substantially prevent detonation from spreading from the combustion chamber via the fuel mixture channel to the mixing chamber. Other embodiments are described and claimed.
FILED	Friday, August 21, 2009
APPL NO	12/545309
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/772
VIEW PATENT	@ USPTO: Full Text PDF

08545142 — Deformation machining systems and methods

US 08545142	Smith et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Kevin Scott Smith (Huntersville, North Carolina); Bethany A. Woody (Charlotte, North Carolina); John C. Ziegert (Seneca, South Carolina); Jian Cao (Wilmette, Illinois)
ASSIGNEE(S)	University of North Carolina at Charlotte (Charlotte, North Carolina); Clemson University (Clemson, South Carolina); Northwestern University (Evanston, Illinois)
INVENTOR(S)	Kevin Scott Smith (Huntersville, North Carolina); Bethany A. Woody (Charlotte, North Carolina); John C. Ziegert (Seneca, South Carolina); Jian Cao (Wilmette, Illinois)
ABSTRACT	The present invention relates generally to deformation machining systems and methods that combine, in a single machine tool setup, the machining of thin structures and single point incremental forming (SPIF), such that novel part geometries and enhanced material properties may be obtained that are not achievable using conventional machining or forming systems and methods, individually or collectively. Important to many applications, lighter weight parts may be produced at lower cost using a conventional 3-axis computer numerically controlled (CNC) machine tool or the like, instead of the conventional 5-axis CNC machine tool or the like that is typically required.
FILED	Friday, March 06, 2009
APPL NO	12/399703
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Gear cutting, milling, or planing 49/80
VIEW PATENT	@ USPTO: Full Text PDF

08545168 — Two-dimensional array of turbines

US 08545168	Dabiri et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	John Oluseun Dabiri (Pasadena, California); Robert W. Whittlesey (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	John Oluseun Dabiri (Pasadena, California); Robert W. Whittlesey (Pasadena, California)
ABSTRACT	Arrangements of turbines are described. The turbines are staggered or aligned in the downwind direction.
FILED	Tuesday, December 22, 2009
APPL NO	12/644667
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Rotary kinetic fluid motors or pumps 415/66
VIEW PATENT	@ USPTO: Full Text PDF

08545543 — Methods and apparatus for microstructure lightguides

US 08545543	Zorzos et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA) NIH Office of the Director (NIHOD) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Anthony Zorzos (Cambridge, Massachusetts); Clifton Fonstad (Arlington, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts); Jacob Bernstein (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Anthony Zorzos (Cambridge, Massachusetts); Clifton Fonstad (Arlington, Massachusetts); Edward Boyden (Chestnut Hill, Massachusetts); Jacob Bernstein (Cambridge, Massachusetts)
ABSTRACT	This invention may be implemented as a microstructure probe for delivering light of variable color and/or power, via a set of integrated lightguides, from an optical source (or set of sources) to regions spatially arranged 3-dimensionally, with a length scale of microns to millimeters. In exemplary embodiments of this invention, a microstructure probe comprises many lightguides and is adapted to be inserted into neural or other tissue. The lightguides run in parallel along at least a portion of the axis of the probe. The probe may deliver light to many points along the axis of insertion of the probe. This invention may be implemented as an array of two or more such probes (each of which comprises multiple lightguides). This array may be used to deliver light to neural tissue in a complex 3D pattern.
FILED	Monday, July 26, 2010
APPL NO	12/843587
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/89
VIEW PATENT	@ USPTO: Full Text PDF

08545559 — Modified metal materials, surface modifications to improve cell interactions and antimicrobial properties, and methods for modifying metal surface properties

US 08545559	Bandyopadhyay et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical and Transport Systems (CTS)
APPLICANT(S)	Amit Bandyopadhyay (Pullman, Washington); Susmita Bose (Pullman, Washington)
ASSIGNEE(S)	Washington State University (Pullman, Washington)
INVENTOR(S)	Amit Bandyopadhyay (Pullman, Washington); Susmita Bose (Pullman, Washington)
ABSTRACT	The present disclosure is directed to modified metal materials for implantation and/or bone replacement, and to methods for modifying surface properties of metal substrates for enhancing cellular adhesion (tissue integration) and providing antimicrobial properties. Some embodiments comprise surface coatings for metal implants, such as titanium-based materials, using (1) electrochemical processing and/or oxidation methods, and/or (2) laser processing, in order to enhance bone cell-materials interactions and achieve improved antimicrobial properties. One embodiment comprises the modification of a metal surface by growth of in situ nanotubes via anodization, followed by electrodeposition of silver on the nanotubes. Other embodiments include the use of LENS™ processing to coat a metal surface with calcium-based bioceramic composition layers. These surface treatment methods can be applied as a post-processing operation to metallic implants such as hip, knee and spinal devices as well as screws, pins and plates.
FILED	Monday, October 06, 2008
APPL NO	12/246455
ART UNIT	3738 — Semiconductors/Memory
CURRENT CPC	Prosthesis 623/16.110
VIEW PATENT	@ USPTO: Full Text PDF

08545627 — Zirconium and hafnium boride alloy templates on silicon for nitride integration applications

US 08545627	Kouvetakis et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	John Kouvetakis (Mesa, Arizona); Radek Roucka (Tempe, Arizona)
ASSIGNEE(S)	Arizona Board of Regents (Scottsdale, Arizona)
INVENTOR(S)	John Kouvetakis (Mesa, Arizona); Radek Roucka (Tempe, Arizona)
ABSTRACT	Semiconductor structures are provided comprising a substrate and a epitaxial layer formed over the substrate, wherein the epitaxial layer comprises B; and one or more element selected from the group consisting of Zr, Hf and Al and has a thickness greater than 50 nm. Further, methods for integrating Group III nitrides onto a substrate comprising, forming an epitaxial buffer layer of a diboride of Zr, Hf, Al, or mixtures thereof, over a substrate; and forming a Group III nitride layer over the buffer layer, are provided which serve to thermally decouple the buffer layer from the underlying substrate, thereby greatly reducing the strain induced in the semiconductor structures upon fabrication and/or operation.
FILED	Tuesday, April 12, 2011
APPL NO	13/085115
ART UNIT	2829 — Semiconductors/Memory
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/108
VIEW PATENT	@ USPTO: Full Text PDF

08545773 — Versatile multichannel capillary biosensor system

US 08545773	Su et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR) National Science Foundation (NSF)
APPLICANT(S)	Xiao-Li Su (Fayetteville, Arkansas); Zungzhong Ye (Hangzhou, China PRC); Qian Sun (Fayetteville, Arkansas); Yanbin Li (Fayetteville, Arkansas)
ASSIGNEE(S)	The Board of Trustees of the University of Arkansas (Little Rock, Arkansas); BioDetection Instruments, LLC (Fayetteville, Arkansas)
INVENTOR(S)	Xiao-Li Su (Fayetteville, Arkansas); Zungzhong Ye (Hangzhou, China PRC); Qian Sun (Fayetteville, Arkansas); Yanbin Li (Fayetteville, Arkansas)
ABSTRACT	The multichannel capillary biosensor system includes a selecting valve system for selection of the sample or a reagent. The selecting valve system is connected to a second valve system accommodating a sensing channel and a first bypass channel. The second valve system is connected to a directing valve system having at least two positions, with a first position being connected to a second bypass channel and a second position being connected to a detector for detecting the analyte. The device has a pump connected at one end to the second bypass channel and the detector and at a second end to a waste vessel. The device also has a control system for controlling the device. The analyte can be selected from the group of microorganisms, macromolecules, and small molecules.
FILED	Thursday, July 24, 2008
APPL NO	12/670467
ART UNIT	1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/537
VIEW PATENT	@ USPTO: Full Text PDF

08545791 — Alkyne-assisted nanostructure growth

US 08545791	Plata et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Desiree L. Plata (Holyoke, Massachusetts); Philip S. Gschwend (Lexington, Massachusetts); Anastasios John Hart (Ann Arbor, Michigan); Eric R. Meshot (Ann Arbor, Michigan); Christopher M. Reddy (Falmouth, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); University of Michigan, The Board of Regents Acting For and On Behalf of the C/O Technology Management Office (Ann Arbor, Michigan); Woods Hole Oceanographic Institute (Woods Hole, Massachusetts)
INVENTOR(S)	Desiree L. Plata (Holyoke, Massachusetts); Philip S. Gschwend (Lexington, Massachusetts); Anastasios John Hart (Ann Arbor, Michigan); Eric R. Meshot (Ann Arbor, Michigan); Christopher M. Reddy (Falmouth, Massachusetts)
ABSTRACT	The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.
FILED	Thursday, June 17, 2010
APPL NO	12/817818
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemistry of inorganic compounds 423/447.300
VIEW PATENT	@ USPTO: Full Text PDF

08546071 — High-throughput in vitro translation (cell-lysate based) assay for detecting quorum sensing signals

US 08546071	Decho et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Emerging Frontiers (EF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Alan W. Decho (Columbia, South Carolina); Tomohiro Kawaguchi (Columbia, South Carolina); Yung-pin Chen (Columbia, South Carolina)
ASSIGNEE(S)	University of South Carolina (Columbia, South Carolina)
INVENTOR(S)	Alan W. Decho (Columbia, South Carolina); Tomohiro Kawaguchi (Columbia, South Carolina); Yung-pin Chen (Columbia, South Carolina)
ABSTRACT	A cell-lysate extract based assay reagent for detecting quorum sensing signals is generally provided, along with methods of making and using the same. The assay reagent generally includes a cell-lysate extract formed from a biosensor bacterium (e.g., Agrobacterium tumefaciens NTL4 (pCF218)(pCF372)) and a detecting substrate (e.g., an absorbance-based or luminescence-based substrate). The cell-lysate extract can be prepared by (1) disrupting the cell membranes of the biosensor bacterium to release the cellular components into a solution, (2) centrifuging the resulting solution, and (3) removing the resulting supernatant solution.
FILED	Monday, July 28, 2008
APPL NO	12/180857
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/4
VIEW PATENT	@ USPTO: Full Text PDF

08546081 — Methods and compositions for assaying a sample for an aggregant

US 08546081	Bazan et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Singapore, Singapore)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Guillermo C. Bazan (Santa Barbara, California); Bin Liu (Singapore, Singapore)
ABSTRACT	This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.
FILED	Monday, February 06, 2012
APPL NO	13/367358
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
VIEW PATENT	@ USPTO: Full Text PDF

08546105 — Engineering intracellular sialylation pathways

US 08546105	Jarvis et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF)
APPLICANT(S)	Donald Jarvis (Laramie, Wyoming); Michael J. Betenbaugh (Baltimore, Maryland); Shawn Lawrence (Valley Cottage, New York); Yuan C. Lee (Timonium, Maryland); Timothy A. Coleman (Derwood, Maryland)
ASSIGNEE(S)	The University of Wyoming (Laramie, Wyoming); The John Hopkins University (Baltimore, Maryland); Human Genome Sciences, Inc. (Rockville, Maryland)
INVENTOR(S)	Donald Jarvis (Laramie, Wyoming); Michael J. Betenbaugh (Baltimore, Maryland); Shawn Lawrence (Valley Cottage, New York); Yuan C. Lee (Timonium, Maryland); Timothy A. Coleman (Derwood, Maryland)
ABSTRACT	Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using recombinant DNA technology and substrate feeding approaches to enable the production of sialylated glycoproteins in cells of interest. These carbohydrate engineering efforts encompass the implementation of new carbohydrate bioassays, the examination of a selection of insect cell lines and the use of bioinformatics to identify gene sequences for critical processing enzymes. The compositions comprise cells of interest producing sialylated glycoproteins. The methods and compositions are useful for heterologous expression of glycoproteins.
FILED	Monday, August 09, 2010
APPL NO	12/806292
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/69.100
VIEW PATENT	@ USPTO: Full Text PDF

08546488 — Cleavable block copolymers, functionalized nanoporous thin films and related methods of preparation

US 08546488	Thayumanavan et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Sankaran Thayumanavan (Amerst, Massachusetts); Akamol Klaikherd (Amherst, Massachusetts); Suhrit Ghosh (Kolkata, India)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Sankaran Thayumanavan (Amerst, Massachusetts); Akamol Klaikherd (Amherst, Massachusetts); Suhrit Ghosh (Kolkata, India)
ABSTRACT	Cleavable, disulfide-coupled block copolymers as can be used in the preparation of nanoporous thin films, micellar configurations and related structures.
FILED	Friday, May 25, 2012
APPL NO	13/506933
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 525/92.J00
VIEW PATENT	@ USPTO: Full Text PDF

08546513 — Catalytic polymerization of polymers containing electrophiic linkages using nucleophilic reagents

US 08546513	Hedrick et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	James L. Hedrick (Pleasanton, California); Russell C. Pratt (Oakland, California); Robert M. Waymouth (Palo Alto, California)
ABSTRACT	The disclosure relates to methods and materials useful for polymerizing a monomer. In one embodiment, for example, the disclosure provides a method for polymerizing a monomer containing a plurality of electrophilic groups, wherein the method comprises contacting the monomer with a nucleophilic reagent in the presence of a guanidine-containing catalyst. The methods and materials of the disclosure find utility, for example, in the field of materials science.
FILED	Monday, January 07, 2013
APPL NO	13/735904
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Synthetic resins or natural rubbers 528/274
VIEW PATENT	@ USPTO: Full Text PDF

08547441 — System and methods for de-blurring motion blurred images

US 08547441	Ben-Ezra et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Moshe Ben-Ezra (Princeton, New Jersey); Shree K. Nayar (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Moshe Ben-Ezra (Princeton, New Jersey); Shree K. Nayar (New York, New York)
ABSTRACT	Systems and methods for providing a substantially de-blurred image of a scene from a motion blurred image of the scene are disclosed. An exemplary system includes a primary detector for sensing the motion blurred image and generating primary image information representing the blurred image, a secondary detector for sensing two or more secondary images of the scene and for generating secondary image information representing the two or more secondary images, and a processor for determining motion information from the secondary image information, estimating a point spread function for the motion blurred image from the motion information, and applying the estimated point spread function to the primary image information to generate information representing the substantially de-blurred image.
FILED	Friday, July 29, 2011
APPL NO	13/194643
ART UNIT	2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Television 348/208.400
VIEW PATENT	@ USPTO: Full Text PDF

08547475 — Imaging arrangements and methods therefor

US 08547475	Ng et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior Univeristy (Palo Alto, California)
INVENTOR(S)	Yi-Ren Ng (San Mateo, California); Patrick M. Hanrahan (Portola Valley, California); Mark A. Horowitz (Menlo Park, California); Marc S. Levoy (Stanford, California)
ABSTRACT	Image data is processed to facilitate focusing and/or optical correction. According to an example embodiment of the present invention, an imaging arrangement collects light data corresponding to light passing through a particular focal plane. The light data is collected using an approach that facilitates the determination of the direction from which various portions of the light incident upon a portion of the focal plane emanate from. Using this directional information in connection with value of the light as detected by photosensors, an image represented by the light is selectively focused and/or corrected.
FILED	Monday, December 17, 2012
APPL NO	13/717397
ART UNIT	2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Television 348/349
VIEW PATENT	@ USPTO: Full Text PDF

08548238 — Method for partitioning combinatorial graphs

US 08548238	Tolliver et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	David Allen Tolliver (Pittsburgh, Pennsylvania); Gary L. Miller (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S)	David Allen Tolliver (Pittsburgh, Pennsylvania); Gary L. Miller (Pittsburgh, Pennsylvania)
ABSTRACT	A method of partitioning a weighted combinatorial graph representative of a dataset consists of the steps of generating a generalized Laplacian matrix corresponding to the combinatorial graph, computing the eigenstructure of the generalized Laplacian matrix, determining if an end criterion is satisfied using the eigenstructure, and if the end criterion is not satisfied, calculating new values for at least some of the plurality of weighting factors using the eigenstructure, updating the combinatorial graph with the new values for at least some of the weighting factors, and returning to the generating step.
FILED	Friday, May 02, 2008
APPL NO	12/150994
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/173
VIEW PATENT	@ USPTO: Full Text PDF

08549208 — Cache memory having enhanced performance and security features

US 08549208	Lee et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Ruby B. Lee (Princeton, New Jersey); Zhenghong Wang (San Jose, California)
ASSIGNEE(S)	Teleputers, LLC (Princeton, New Jersey)
INVENTOR(S)	Ruby B. Lee (Princeton, New Jersey); Zhenghong Wang (San Jose, California)
ABSTRACT	A cache memory having enhanced performance and security feature is provided. The cache memory includes a data array storing a plurality of data elements, a tag array storing a plurality of tags corresponding to the plurality of data elements, and an address decoder which permits dynamic memory-to-cache mapping to provide enhanced security of the data elements, as well as enhanced performance. The address decoder receives a context identifier and a plurality of index bits of an address passed to the cache memory, and determines whether a matching value in a line number register exists. The line number registers allow for dynamic memory-to-cache mapping, and their contents can be modified as desired. Methods for accessing and replacing data in a cache memory are also provided, wherein a plurality of index bits and a plurality of tag bits at the cache memory are received. The plurality of index bits are processed to determine whether a matching index exists in the cache memory and the plurality of tag bits are processed to determine whether a matching tag exists in the cache memory, and a data line is retrieved from the cache memory if both a matching tag and a matching index exist in the cache memory. A random line in the cache memory can be replaced with a data line from a main memory, or evicted without replacement, based on the combination of index and tag misses, security contexts and protection bits. User-defined and/or vendor-defined replacement procedures can be utilized to replace data lines in the cache memory.
FILED	Tuesday, December 08, 2009
APPL NO	12/633500
ART UNIT	2188 — Computer Architecture and I/O
CURRENT CPC	Electrical computers and digital processing systems: Memory 711/3
VIEW PATENT	@ USPTO: Full Text PDF

08549499 — Parallel programming using possible parallel regions and its language profiling compiler, run-time system and debugging support

US 08549499	Ding et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Chen Ding (Rochester, New York); Xipeng Shen (Williamsburg, Virginia); Ruke Huang (Edmonds, Washington)
ASSIGNEE(S)	University of Rochester (Rochester, New York)
INVENTOR(S)	Chen Ding (Rochester, New York); Xipeng Shen (Williamsburg, Virginia); Ruke Huang (Edmonds, Washington)
ABSTRACT	A method of dynamic parallelization for programs in systems having at least two processors includes examining computer code of a program to be performed by the system, determining a largest possible parallel region in the computer code, classifying data to be used by the program based on a usage pattern and initiating multiple, concurrent processes to perform the program. The multiple, concurrent processes ensure a baseline performance that is at least as efficient as a sequential performance of the computer code.
FILED	Monday, June 18, 2007
APPL NO	11/812368
ART UNIT	2192 — Interprocess Communication and Software Development
CURRENT CPC	Data processing: Software development, installation, and management 717/149
VIEW PATENT	@ USPTO: Full Text PDF

08549646 — Methods, media and systems for responding to a denial of service attack

US 08549646	Stavrou et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Angelos Stavrou (New York, New York); Angelos D. Keromytis (New York, New York); Jason Nieh (New York, New York); Vishal Misra (New York, New York); Daniel Rubenstein (New York, New York)
ASSIGNEE(S)	The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S)	Angelos Stavrou (New York, New York); Angelos D. Keromytis (New York, New York); Jason Nieh (New York, New York); Vishal Misra (New York, New York); Daniel Rubenstein (New York, New York)
ABSTRACT	Methods, media and systems for responding to a Denial of Service (DoS) attack are provided. In some embodiments, a method includes detecting a DoS attack, migrating one or more processes that provide a service to an unaffected system; authenticating users that are authorized to use the service; and routing traffic generated by authenticated users to the unaffected system.
FILED	Friday, October 20, 2006
APPL NO	11/584312
ART UNIT	2433 — Cryptography and Security
CURRENT CPC	Information security 726/24
VIEW PATENT	@ USPTO: Full Text PDF

08549660 — Cantilever-based optical fiber probe interfacial force microscope for partial immersion in liquid

US 08549660	Kim
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Byung Kim (Boise, Idaho)
ASSIGNEE(S)	Boise State University (Boise, Idaho)
INVENTOR(S)	Byung Kim (Boise, Idaho)
ABSTRACT	An apparatus may comprise an optical detector configured to detect an optical beam reflected from a cantilever. The apparatus may further comprise an optical fiber probe suspended from the cantilever and a piezotube configured to move a sample substance in proximity to the optical fiber probe. The cantilever may be configured to deflect in response to an interfacial force between the sample substance and the optical fiber probe. The apparatus may further comprise a feedback controller communicatively coupled to the optical detector and a semiconductive circuit element abutting the cantilever. In response to detecting movement of the optical beam reflected from the cantilever, the feedback controller may apply a voltage to the semiconductive circuit element, which may reduce deflection of the cantilever. The voltage applied by the feedback controller may indicate a strength of the interfacial force between the sample substance and the optical fiber probe.
FILED	Friday, April 09, 2010
APPL NO	12/757542
ART UNIT	2881 — Optics
CURRENT CPC	Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/15
VIEW PATENT	@ USPTO: Full Text PDF

Department of Commerce (DOC)

08545629 — Method and apparatus for producing large, single-crystals of aluminum nitride

US 08545629	Schowalter et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR) Missile Defense Agency (MDA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (Setauket, New York); Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Joseph A. Smart (Mooresville, North Carolina)
ASSIGNEE(S)	Crystal IS, Inc. (Green Island, New York)
INVENTOR(S)	Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (Setauket, New York); Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Joseph A. Smart (Mooresville, North Carolina)
ABSTRACT	Bulk single crystals of AlN having a diameter greater than about 25 mm and dislocation densities of about 10,000 cm⁻²or less and high-quality AlN substrates having surfaces of any desired crystallographic orientation fabricated from these bulk crystals.
FILED	Tuesday, May 09, 2006
APPL NO	11/431090
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/952
VIEW PATENT	@ USPTO: Full Text PDF

08545709 — Critical dimension control during template formation

US 08545709	Brooks et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Cynthia B. Brooks (Austin, Texas); Dwayne L. LaBrake (Cedar Park, Texas); Niyaz Khusnatdinov (Round Rock, Texas); Michael N. Miller (Austin, Texas); Sidlgata V. Sreenivasan (Austin, Texas); David James Lentz (Leander, Texas); Frank Y. Xu (Round Rock, Texas)
ASSIGNEE(S)	Molecular Imprints, Inc. (Austin, Texas)
INVENTOR(S)	Cynthia B. Brooks (Austin, Texas); Dwayne L. LaBrake (Cedar Park, Texas); Niyaz Khusnatdinov (Round Rock, Texas); Michael N. Miller (Austin, Texas); Sidlgata V. Sreenivasan (Austin, Texas); David James Lentz (Leander, Texas); Frank Y. Xu (Round Rock, Texas)
ABSTRACT	Thickness of a residual layer may be altered to control critical dimension of features in a patterned layer provided by an imprint lithography process. The thickness of the residual layer may be directly proportional or inversely proportional to the critical dimension of features. Dispensing techniques and material selection may also provide control of the critical dimension of features in the patterned layer.
FILED	Friday, April 06, 2012
APPL NO	13/441500
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Etching a substrate: Processes 216/41
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

08545629 — Method and apparatus for producing large, single-crystals of aluminum nitride

US 08545629	Schowalter et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) Air Force Research Laboratory (AFRL) Department of the Navy (DON) Office of Naval Research (ONR) Missile Defense Agency (MDA) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (Setauket, New York); Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Joseph A. Smart (Mooresville, North Carolina)
ASSIGNEE(S)	Crystal IS, Inc. (Green Island, New York)
INVENTOR(S)	Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York); J. Carlos Rojo (Setauket, New York); Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Joseph A. Smart (Mooresville, North Carolina)
ABSTRACT	Bulk single crystals of AlN having a diameter greater than about 25 mm and dislocation densities of about 10,000 cm⁻²or less and high-quality AlN substrates having surfaces of any desired crystallographic orientation fabricated from these bulk crystals.
FILED	Tuesday, May 09, 2006
APPL NO	11/431090
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/952
VIEW PATENT	@ USPTO: Full Text PDF

08545692 — Apparatus and method for electrochemical modification of concentrations of liquid streams

US 08545692	James et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Patrick Ismail James (Madison, Wisconsin); George Stejic (Arlington, Virginia)
ASSIGNEE(S)
INVENTOR(S)	Patrick Ismail James (Madison, Wisconsin); George Stejic (Arlington, Virginia)
ABSTRACT	An apparatus and a method for electrochemical modification of liquid streams using at least one anode and cathode assemblies arranged to contain liquid electrolytes anolyte and catholyte, a plurality of electrically conducting anode and cathode particulates forming anode and cathode particulate beds, and current feeder and current collector devices in contact with the particulate bed, where the anode particulates and cathode particulates are in motion substantially independent of bulk electrolytes flow.
FILED	Friday, May 27, 2011
APPL NO	13/117769
ART UNIT	1756 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/753
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

08545991 — Low thermal conductivity misfit layer compounds with layer to layer disorder

US 08545991	Johnson et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) U.S. State Government State of Oregon
APPLICANT(S)	David C. Johnson (Eugene, Oregon); Ngoc T. Nguyen (Eugene, Oregon); Qiyin Lin (Darien, Illinois); Colby L. Heideman (Springfield, Oregon); Clay Mortensen (Portland, Oregon)
ASSIGNEE(S)	State of Oregon Acting by and Through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon)
INVENTOR(S)	David C. Johnson (Eugene, Oregon); Ngoc T. Nguyen (Eugene, Oregon); Qiyin Lin (Darien, Illinois); Colby L. Heideman (Springfield, Oregon); Clay Mortensen (Portland, Oregon)
ABSTRACT	Compositions comprise an alternating plurality of ordered layers of a first composition MX and a second composition TX₂, wherein M is one of Sn, Pb, Sb, Bi, or a rare earth metal, X is S or Se and T is Ti, V, Cr, Nb, or Ta. In some examples, the alternating plurality of ordered layers conforms to a substrate. In typical examples, each of the ordered layers of the first composition has a common thickness and/or each of the ordered layers of the first material has a common composition. In some examples, each of the ordered layers of the second composition has a common thickness and/or a common composition.
FILED	Monday, January 25, 2010
APPL NO	12/693376
ART UNIT	1784 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/635
VIEW PATENT	@ USPTO: Full Text PDF

08548734 — System and method for real-time travel path prediction and automatic incident alerts

US 08548734	Barbeau et al.
FUNDED BY	Department of Transportation (USDOT) U.S. State Government State of Florida Florida Department of Transportation (FDOT)
APPLICANT(S)	Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida)
ABSTRACT	A path prediction method that uses a commuter's travel patterns to predict their route and destination, and transmit road advisories via a GPS-enabled device. Once the user's location data is transmitted via a GPS-enabled device it is then catalogued and stored in a GIS database. The user's current travel path is then compared to their path history and statistics and a destination is determined based on related spatial and time properties. A warning is then automatically delivered to the user if there is an accident along their predicted path, without requiring any request or input form the user.
FILED	Friday, September 14, 2007
APPL NO	11/855694
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/411
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

08548734 — System and method for real-time travel path prediction and automatic incident alerts

US 08548734	Barbeau et al.
FUNDED BY	Department of Transportation (USDOT) U.S. State Government State of Florida Florida Department of Transportation (FDOT)
APPLICANT(S)	Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida)
ABSTRACT	A path prediction method that uses a commuter's travel patterns to predict their route and destination, and transmit road advisories via a GPS-enabled device. Once the user's location data is transmitted via a GPS-enabled device it is then catalogued and stored in a GIS database. The user's current travel path is then compared to their path history and statistics and a destination is determined based on related spatial and time properties. A warning is then automatically delivered to the user if there is an accident along their predicted path, without requiring any request or input form the user.
FILED	Friday, September 14, 2007
APPL NO	11/855694
ART UNIT	3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/411
VIEW PATENT	@ USPTO: Full Text PDF

Department of Veterans Affairs (DVA)

08546134 — Method for isolating nuclei

US 08546134	Nagata
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Takako Nagata (Washington, District of Columbia)
ASSIGNEE(S)	The George Washington University (Washington, District of Columbia); The United States of America as Represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S)	Takako Nagata (Washington, District of Columbia)
ABSTRACT	This invention relates to methods of isolating cell nuclei from the other cell components in cell samples, e.g., cell samples from cell cultures or tissue samples. The method does not comprise ultracentrifugation or super-centrifugation rather the method comprises centrifuging cell samples in a table-top conventional centrifuge or microfuge. The method also comprises the use of buffers that are substantially devoid of protease inhibitor or enzyme treatments. The methods facilitate separation of nuclei from nuclear outer membranes leaving the cellular structures and inner membranes of nuclei intact. The method also provides for rapid and consistent results.
FILED	Monday, December 06, 2010
APPL NO	12/960688
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/317.100
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

08549496 — Method, apparatus and computer program product for automatically generating a computer program using consume, simplify and produce semantics with normalize, transpose and distribute operations

US 08549496	Cooke et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC)
APPLICANT(S)	Daniel E. Cooke (Lubbock, Texas); J. Nelson Rushton (Lubbock, Texas); Brad Nemanich (Lubbock, Texas)
ASSIGNEE(S)	Texas Tech University System (Lubbock, Texas)
INVENTOR(S)	Daniel E. Cooke (Lubbock, Texas); J. Nelson Rushton (Lubbock, Texas); Brad Nemanich (Lubbock, Texas)
ABSTRACT	A code generator and multi-core framework are executable in a computer system to implement methods as disclosed herein, including a method for the code generator to automatically generate multi-threaded source code from functional specifications, and for the multi-core framework, which is a run time component, to generate multi-threaded task object code from the multi-threaded source code and to execute the multi-threaded task object code on respective processor cores. The methods provide transparency to the programmer, and during execution, provide automatic identification of processing parallelisms. The methods implement Consume-Simplify-Produce and Normalize-Transpose-Distribute operations to reduce complex expression sets in a functional specification to simplified expression sets operable in parallel processing environments through the generated multi-threaded task object code. The result is a code generator which compiles transparent declarative code into multi-threaded code and that in the process identifies and assigns parallel processing paths to improve overall processing performance.
FILED	Wednesday, February 24, 2010
APPL NO	12/711614
ART UNIT	2191 — Interprocess Communication and Software Development
CURRENT CPC	Data processing: Software development, installation, and management 717/146
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

08548931 — System and method for electronic transaction verification

US 08548931	Bonnell et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	Clayton Bonnell (Fairfax, Virginia); Ronald Garey (Mitchelville, Maryland); Bradley Reck (Sterling, Virginia); Gregory Crabb (Broadlands, Virginia)
ASSIGNEE(S)	United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	Clayton Bonnell (Fairfax, Virginia); Ronald Garey (Mitchelville, Maryland); Bradley Reck (Sterling, Virginia); Gregory Crabb (Broadlands, Virginia)
ABSTRACT	A system and method for authenticating a physical address submitted in an online communication is disclosed. An online communication comprising a physical address to be verified is received. A verification identification (VID) is requested and received. A transaction verification document (TVD) comprising an indicia indicative of the VID is generated. An electronic copy of the TVD is transmitted. Verification data produced in response to dispatch of a physical embodiment of the TVD is received, wherein the physical embodiment is generated from the electronic copy. The physical address is authenticated based at least in part on the verification data.
FILED	Monday, July 02, 2012
APPL NO	13/540265
ART UNIT	3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC	Data processing: Financial, business practice, management, or cost/price determination 75/330
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

08545625 — Materials for dental and biomedical application

US 08545625	Wen et al.
FUNDED BY
APPLICANT(S)	Hai Bo Wen (Warsaw, Indiana); Janet Moradian-Oldak (Los Angeles, California)
ASSIGNEE(S)	University of Southern California (Los Angeles, California)
INVENTOR(S)	Hai Bo Wen (Warsaw, Indiana); Janet Moradian-Oldak (Los Angeles, California)
ABSTRACT	The invention provides novel dental enamel inspired materials for biomedical and dental applications. The materials are apatite-like calcium phosphate complexes and may comprise apatite, octacalcium phosphate crystals, or mixtures thereof. In one embodiment, the materials (calcium phosphate coatings) are mixtures of crystals of apatite and its precursor, octacalcium phosphate, nucleated on a titanium surface. They are prepared using a chemical process leading to the formation of biological apatite which is similar to that found in natural bone and teeth. In one embodiment, the materials are prepared by placing a titanium substrate in a supersaturated calcifying solution containing native or purified recombinant amelogenins. The presence of the amelogenins modulates apatite crystal growth to mimic in vivo apatite crystal formation. Applications for the materials include, without limitation, dental tissue (enamel, dentin, cementum) replacement, orthopeadic implants for bone repair, and coatings for improving the biocompatibility and bone regeneration capability of currently available implants or medical devices made of metallic, polymeric, ceramic or composite materials.
FILED	Tuesday, September 12, 2006
APPL NO	11/518984
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/75
VIEW PATENT	@ USPTO: Full Text PDF

08545986 — Composite insulated conductor

US 08545986	Pater
FUNDED BY
APPLICANT(S)	Ruth H. Pater (Yorktown, Virginia)
ASSIGNEE(S)	United States of America as represented by the Administrator of the National Aeronautics and Spacing Administration (Washington, District of Columbia)
INVENTOR(S)	Ruth H. Pater (Yorktown, Virginia)
ABSTRACT	A composite conductor includes a conductor that has a high temperature polyimide insulation formed around it. This polyimide layer may include reinforcing fibers such as, for instance, glass fibers. The insulation layer may further include grading layers. The conductor is placed inside an earth layer. The composite conductor may be protected with a stainless steel enclosure.
FILED	Thursday, March 06, 2008
APPL NO	12/043276
ART UNIT	1786 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/435
VIEW PATENT	@ USPTO: Full Text PDF

08546785 — Memristive device

US 08546785	Yang et al.
FUNDED BY
APPLICANT(S)	Jianhua Yang (Palo Alto, California); Feng Miao (Mountain View, California); Wei Wu (Palo Alto, California); Shih-Yuan Wang (Palo Alto, California); R. Stanley Williams (Portola Valley, California)
ASSIGNEE(S)	Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S)	Jianhua Yang (Palo Alto, California); Feng Miao (Mountain View, California); Wei Wu (Palo Alto, California); Shih-Yuan Wang (Palo Alto, California); R. Stanley Williams (Portola Valley, California)
ABSTRACT	A memristive device includes a first electrode and a second electrode crossing the first electrode at a non-zero angle. An active region is disposed between the first and second electrodes. The active region has defects therein. Graphene or graphite is disposed between the active region and the first electrode and/or between the active region and the second electrode.
FILED	Wednesday, March 31, 2010
APPL NO	12/751977
ART UNIT	2829 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/5
VIEW PATENT	@ USPTO: Full Text PDF

08547531 — Imaging device

US 08547531	Krainak
FUNDED BY
APPLICANT(S)	Michael A. Krainak (Fulton, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics Space Administration (Washington, District of Columbia)
INVENTOR(S)	Michael A. Krainak (Fulton, Maryland)
ABSTRACT	Disclosed is an apparatus and method for imaging a target area. Light is emitted from a device and separated into individual rays of light. These rays are then directed to a target area where they are reflected and returned to a receiving device. The time of flight for the individual rays of light is calculated to determine the range and shape of objects in the target area.
FILED	Wednesday, September 01, 2010
APPL NO	12/873373
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Optics: Measuring and testing 356/4.10
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 01, 2013.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20131001.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital