FedInvent™ Patents

Patent Details for Tuesday, October 08, 2013 

This page was updated on Monday, March 27, 2023 at 03:51 AM GMT

Department of Health and Human Services (HHS) 

US 08549933 Shih et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Wan Y. Shih (Bryn Mawr, Pennsylvania);  Wei-Heng Shih (Bryn Mawr, Pennsylvania);  Anna Markidou (Souni-Limassol, Cyprus);  Steven T. Szweczyk (Springfield, Pennsylvania);  Hakki Yegingil (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Wan Y. Shih (Bryn Mawr, Pennsylvania);  Wei-Heng Shih (Bryn Mawr, Pennsylvania);  Anna Markidou (Souni-Limassol, Cyprus);  Steven T. Szweczyk (Springfield, Pennsylvania);  Hakki Yegingil (Philadelphia, Pennsylvania)
ABSTRACT A PEFS (Piezoelectric Finger Sensor) acts as an “electronic finger” capable of accurately and non-destructively measuring both the Young's compression modulus and shear modulus of tissues with gentle touches to the surface. The PEFS measures both the Young's compression modulus and shear modulus variations in tissue generating a less than one-millimeter spatial resolution up to a depth of several centimeters. This offers great potential for in-vivo early detection of diseases. A portable hand-held device is also disclosed. The PEF offers superior sensitivity.
FILED Friday, October 07, 2011
APPL NO 13/268225
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/862.639
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08550119 Unger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Marc A. Unger (South San Francisco, California);  Hou-Pu Chou (Foster City, California);  Todd A. Thorsen (Pasadena, California);  Axel Scherer (Laguna Beach, California);  Stephen R. Quake (San Marino, California);  Markus Enzelberger (Pasadena, California);  Mark L. Adams (Pasadena, California);  Carl L. Hansen (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Marc A. Unger (South San Francisco, California);  Hou-Pu Chou (Foster City, California);  Todd A. Thorsen (Pasadena, California);  Axel Scherer (Laguna Beach, California);  Stephen R. Quake (San Marino, California);  Markus Enzelberger (Pasadena, California);  Mark L. Adams (Pasadena, California);  Carl L. Hansen (Pasadena, California)
ABSTRACT A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.
FILED Wednesday, October 31, 2007
APPL NO 11/932552
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Fluid handling
137/829
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08550974 Jarvik
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Robert Jarvik (New York, New York)
ASSIGNEE(S)
INVENTOR(S) Robert Jarvik (New York, New York)
ABSTRACT Highly miniaturized electromechanical medical implants for certain applications cannot be fit into the available anatomic space unless their diameter can be made small enough. With devices such as rotary blood pumps or linear actuators, using rotary or linear electric motors, a thin motor stator that provides sufficient power must be encased in a corrosion resistant hermetically sealed enclosure into which electric wires must pass. Hermetic feedthroughs of the prior art are not structurally suited to maximal miniaturization with optimal electrical properties because of the need for welding of ferrules or other support components. The sub-miniature medical implants having the robust feedthrough of the present invention integrate the feedthrough wires, insulators, and sealing within a radially extending flange that is part of the end wall of the motor enclosure. This permits the largest feedthrough wire and thickest insulator to be built into the limited available space.
FILED Thursday, November 13, 2008
APPL NO 12/291682
ART UNIT 3766 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Surgery
6/16
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US 08551271 Ok et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Jerry Ok (Canyon Country, California);  Robert J. Greenberg (Los Angeles, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Jerry Ok (Canyon Country, California);  Robert J. Greenberg (Los Angeles, California)
ABSTRACT A method for fabricating a hermetically sealed electrical feedthrough. The method provides a ceramic sheet and forming at least one via hole in the ceramic sheet, inserting a conductive thickfilm paste into the via hole, laminating the ceramic sheet that has a paste filled via hole between an upper ceramic sheet and a lower ceramic sheet to form an integral ceramic substrate, firing the laminated ceramic substrate to sinter the ceramic substrate and cause the paste filled via hole to form a metalized via while the laminated ceramic substrate form a hermetic seal around the metalized via. The upper ceramic sheet and the lower ceramic sheet are removed from the fired ceramic substrate to expose the upper and lower surface of the metalized via.
FILED Thursday, October 25, 2007
APPL NO 11/924408
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/89.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551322 Schoenfisch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Mark H. Schoenfisch (Chapel Hill, North Carolina);  Jae Ho Shin (Chapel Hill, North Carolina)
ASSIGNEE(S) University of North Carolina at Chapel Hill (, None)
INVENTOR(S) Mark H. Schoenfisch (Chapel Hill, North Carolina);  Jae Ho Shin (Chapel Hill, North Carolina)
ABSTRACT The presently disclosed subject matter relates to sensors for measuring an amount of a gaseous species in a sample. The sensors comprise a gas permeable polysiloxane network membrane, comprising both alkyl and fluorinated alkyl groups. In some embodiments, the polysiloxane network can be formed from the co-condensation of a mixture of an alkylalkoxysilane and a fluorosilane. The presently disclosed subject matter also relates to methods of making the sensors, methods of selectively measuring an amount of a gaseous species, such as nitric oxide, in a sample, and to compositions comprising the polysiloxane networks.
FILED Friday, August 24, 2007
APPL NO 12/374932
ART UNIT 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/781
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US 08551333 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Adam Yuh Lin (Irvine, California);  Tak Sing Wong (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Adam Yuh Lin (Irvine, California);  Tak Sing Wong (Los Angeles, California)
ABSTRACT A microfluidic device for manipulating particles in a fluid has a device body that defines a main channel therein, in which the main channel has an inlet and an outlet. The device body further defines a particulate diverting channel therein, the particulate diverting channel being in fluid connection with the main channel between the inlet and the outlet of the main channel and having a particulate outlet. The microfluidic device also has a plurality of microparticles arranged proximate or in the main channel between the inlet of the main channel and the fluid connection of the particulate diverting channel to the main channel. The plurality of microparticles each comprises a material in a composition thereof having a magnetic susceptibility suitable to cause concentration of magnetic field lines of an applied magnetic field while in operation. A microfluidic particle-manipulation system has a microfluidic particle-manipulation device and a magnet disposed proximate the microfluidic particle-manipulation device.
FILED Monday, April 07, 2008
APPL NO 12/594179
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/222
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US 08551425 Goldkorn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Amir Goldkorn (Beverly Hills, California);  Yu-Chong Tai (Pasadena, California);  Tong Xu (South Pasadena, California);  Bo Lu (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California);  Univeristy of Southern California (Los Angeles, California)
INVENTOR(S) Amir Goldkorn (Beverly Hills, California);  Yu-Chong Tai (Pasadena, California);  Tong Xu (South Pasadena, California);  Bo Lu (Pasadena, California)
ABSTRACT The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.
FILED Thursday, May 20, 2010
APPL NO 12/784446
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/534
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US 08551448 VanBrocklin et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Henry F. VanBrocklin (Walnut Creek, California);  James P. O'Neil (San Leandro, California);  Andrew R. Gibbs (Pleasant Hill, California);  Nandanan Erathodiyil (Singapore, Singapore)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Henry F. VanBrocklin (Walnut Creek, California);  James P. O'Neil (San Leandro, California);  Andrew R. Gibbs (Pleasant Hill, California);  Nandanan Erathodiyil (Singapore, Singapore)
ABSTRACT The present invention provides rotenone analogs and methods of making and using them. Labeled with single photon and positron emitting isotopes, the rotenone analogs of the present invention are useful in, for example, clinical imaging applications as tracers to measure cardiac blood flow and detect regions of ischemia.
FILED Tuesday, November 18, 2008
APPL NO 12/273509
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.810
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551453 Raymond et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Kenneth N. Raymond (Berkeley, California);  Stephane Petoud (Pittsburgh, Pennsylvania);  Jide Xu (Berkeley, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kenneth N. Raymond (Berkeley, California);  Stephane Petoud (Pittsburgh, Pennsylvania);  Jide Xu (Berkeley, California)
ABSTRACT The present invention provides luminescent lanthanide metal chelates comprising a metal ion of the lanthanide series and a complexing agent comprising at least one phthalamidyl moiety. Also provided are probes incorporating the phthalamidyl ligands of the invention and methods utilizing the ligands of the invention and probes comprising the ligands of the invention.
FILED Wednesday, December 29, 2004
APPL NO 10/585178
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.600
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US 08551467 Sullivan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Benjamin Sullivan (San Diego, California);  Tannin A. Schmidt (Calbary, California);  David A. Sullivan (Boston, Massachusetts)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Schepens Eye Research Institute (Boston, Massachusetts)
INVENTOR(S) Benjamin Sullivan (San Diego, California);  Tannin A. Schmidt (Calbary, California);  David A. Sullivan (Boston, Massachusetts)
ABSTRACT An ophthalmic composition, and methods of use thereof, including for treating ocular boundary deficiency, symptoms associated therewith, or undesired condition that is associated with or causes ocular boundary deficiency at the ocular surface or for the treatment or care of ophthalmic devices. The ophthalmic composition comprises a human PRG4 protein, a lubricant fragment, homolog, or isoform thereof, suspended in an ophthalmically acceptable balanced salt solution. The ophthalmic composition may also comprise one or more ophthalmically acceptable agents.
FILED Monday, July 02, 2012
APPL NO 13/539986
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/78.40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551477 Croft et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Michael Croft (San Diego, California);  Shahram Salek-Ardakani (San Diego, California)
ASSIGNEE(S) La Jolla Institute for Allergy and Immunology (La Jolla, California)
INVENTOR(S) Michael Croft (San Diego, California);  Shahram Salek-Ardakani (San Diego, California)
ABSTRACT T cell memory can persist in the absence of antigen. However, some memory cells by default are subject to signals accompanying periodic antigen exposure. OX40 is essential to the extent and persistence of Th2 memory when antigen is re-encountered. In an animal model of allergic asthma, inhibiting OX40/OX40L signaling during the secondary response to inhaled antigen suppressed lung inflammation. Inhibiting OX40 at the time of memory cell reactivation reduced the longevity of memory with further inflammation prevented upon tertiary encounter with antigen.
FILED Monday, December 19, 2011
APPL NO 13/329811
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551480 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Chien-Hsing Chang (Downingtown, Pennsylvania);  David M. Goldenberg (Mendham, New Jersey);  Edmund A. Rossi (Woodland Park, New Jersey)
ASSIGNEE(S) Immunomedics, Inc. (, None);  IBC Pharmaceuticals, Inc. (Morris Plains, New Jersey)
INVENTOR(S) Chien-Hsing Chang (Downingtown, Pennsylvania);  David M. Goldenberg (Mendham, New Jersey);  Edmund A. Rossi (Woodland Park, New Jersey)
ABSTRACT The present invention concerns methods and compositions for forming immunotoxin complexes having a high efficacy and low systemic toxicity. In preferred embodiments, the toxin moiety is a ranpirnase (Rap), such as Rap(Q). In more preferred embodiments, the immunotoxin is made using dock-and-lock (DNL) technology. The immunotoxin exhibits improved pharmacokinetics, with a longer serum half-life and significantly greater efficacy compared to toxin alone, antibody alone, unconjugated toxin plus antibody or even other types of toxin-antibody constructs. In a most preferred embodiment the construct comprises an anti-Trop-2 antibody conjugated to Rap, although other combinations of antibodies, antibody fragments and toxins may be used to form the subject immunotoxins. The immunotoxins are of use to treat a variety of diseases, such as cancer, autoimmune disease or immune dysfunction.
FILED Monday, August 30, 2010
APPL NO 12/871345
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/134.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551481 Pardoll et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Drew M Pardoll (Brookeville, Maryland);  Ching-Tai Huang (Taipei, Taiwan);  Jonathan Powell (Baltimore, Maryland);  Charles Drake (Baltimore, Maryland);  Dario A Vignali (Germantown, Tennessee);  Creg J Workman (Memphis, Tennessee)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee)
INVENTOR(S) Drew M Pardoll (Brookeville, Maryland);  Ching-Tai Huang (Taipei, Taiwan);  Jonathan Powell (Baltimore, Maryland);  Charles Drake (Baltimore, Maryland);  Dario A Vignali (Germantown, Tennessee);  Creg J Workman (Memphis, Tennessee)
ABSTRACT Regulatory T cells (Treg) limit autoimmunity but can also attenuate the magnitude of anti-pathogen and anti-tumor immunity. Understanding the mechanism of Treg function and therapeutic manipulation of Treg in vivo requires identification of Treg selective receptors. A comparative analysis of gene expression arrays from antigen specific CD4+ T cells differentiating to either an effector/memory or a regulatory phenotype revealed Treg selective expression of LAG-3 (CD223), a CD4-related molecule that binds MHC class II. LAG-3 expression on CD4+ T cells correlates with the cells' in vitro suppressor activity, and ectopic expression of LAG-3 on CD4 T cells confers suppressor activity on the T cells. Antibodies to LAG-3 inhibit suppression both in vitro and in vivo. LAG-3 marks regulatory T cell populations and contributes to their suppressor activity.
FILED Thursday, October 22, 2009
APPL NO 12/578887
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/139.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551489 Moussa et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Omar Moussa (Charleston, South Carolina);  Dennis K. Watson (Charleston, South Carolina);  Perry V. Halushka (Charleston, South Carolina)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Omar Moussa (Charleston, South Carolina);  Dennis K. Watson (Charleston, South Carolina);  Perry V. Halushka (Charleston, South Carolina)
ABSTRACT Methods for the treatment of cancers involving dysregulation of thromboxane receptor β (TP-β) are provided, including in certain aspects methods for diagnosing such cancers. Specific cancers included are genitourinary cancers, gastrointestinal cancers and leukemias.
FILED Friday, January 02, 2009
APPL NO 12/811321
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/174.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551536 Gladwin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Mark T. Gladwin (Pittsburg, Pennsylvania);  Daniel B. Kim-Shapiro (Winston-Salem, North Carolina);  Rakesh P. Patel (Hoover, Alabama);  Jeffrey Kerby (Birmingham, Alabama)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  University of Alabama at Birmingham (Birmingham, Alabama);  Wake Forest University (Winston-Salem, North Carolina)
INVENTOR(S) Mark T. Gladwin (Pittsburg, Pennsylvania);  Daniel B. Kim-Shapiro (Winston-Salem, North Carolina);  Rakesh P. Patel (Hoover, Alabama);  Jeffrey Kerby (Birmingham, Alabama)
ABSTRACT This disclosure relates to methods of using nitrite to detoxify stroma-free hemoglobin based blood substitutes. In particular, methods are described for using a blood substitute comprised of about equimolar amounts of nitrite and hemoglobin (e.g., nitrite-metHb) to treat, prevent, or ameliorate diseases of the blood in a subject, or as a blood replacement in a subject.
FILED Friday, August 29, 2008
APPL NO 12/675347
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/718
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551568 Messersmith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Phillip B. Messersmith (Clarendon Hills, Illinois);  Haeshin Lee (Chicago, Illinois);  Yuhan Lee (Daejeon, South Korea);  Zhongqiang Liu (Evanston, Illinois);  Lesley Hamming (Durham, North Carolina)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Phillip B. Messersmith (Clarendon Hills, Illinois);  Haeshin Lee (Chicago, Illinois);  Yuhan Lee (Daejeon, South Korea);  Zhongqiang Liu (Evanston, Illinois);  Lesley Hamming (Durham, North Carolina)
ABSTRACT The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.
FILED Tuesday, September 18, 2012
APPL NO 13/622136
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Coating processes
427/352
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US 08551599 Hua et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Zhishan Hua (Raleigh, North Carolina);  Erdogan Gulari (Ann Arbor, Michigan);  Mark A. Burns (Ann Arbor, Michigan);  Rohit Pal (Fishkill, New York);  Onnop Srivannavit (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Zhishan Hua (Raleigh, North Carolina);  Erdogan Gulari (Ann Arbor, Michigan);  Mark A. Burns (Ann Arbor, Michigan);  Rohit Pal (Fishkill, New York);  Onnop Srivannavit (Ann Arbor, Michigan)
ABSTRACT A microactuator may be configured by activating a source of electromagnetic radiation to heat and melt a selected set of phase-change plugs embedded in a substrate of the microactuator, pressurizing a common pressure chamber adjacent to each of the plugs to deform the melted plugs, and deactivating the source of electromagnetic radiation to cool and solidify the melted plugs.
FILED Monday, August 31, 2009
APPL NO 12/551071
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/138
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US 08551698 Brown et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) James F. Brown (Clifton, Virginia);  Jonathan E. Silver (Bethesda, Maryland)
ASSIGNEE(S) Applied Biosystems, LLC (Carlsbad, California);  The United States Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) James F. Brown (Clifton, Virginia);  Jonathan E. Silver (Bethesda, Maryland)
ABSTRACT A method comprising loading a sample into a microfluidic device which comprises plural sample chambers, subdividing the sample into a plurality of sample portions, such that respective sample portions are positioned in each of a plurality of the sample chambers, and subjecting the sample portions loaded into the respective sample chambers to at least a first amplification step. Each of the sample chambers has a respective volume such that if a sample portion positioned in the sample chamber comprises at least one molecule of a target nucleic acid, the target nucleic acid would attain a detectable concentration in the sample chamber after a single round of amplification.
FILED Monday, August 13, 2007
APPL NO 11/837608
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551699 Bussemakers et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Marion J. G. Bussemakers (Nijmegen, Netherlands);  William B. Isaacs (Glyndon, Maryland)
ASSIGNEE(S) Stichting Katholieke Universiteit, more particularly The University of Medical Centre Nijmegen (Nijmegen, Netherlands);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Marion J. G. Bussemakers (Nijmegen, Netherlands);  William B. Isaacs (Glyndon, Maryland)
ABSTRACT The present invention relates, in general, to a prostate-specific antigen, PCA3. In particular, the present invention relates to nucleic acid molecules coding for the PCA3 protein; purified PCA3 proteins and polypeptides; recombinant nucleic acid molecules; cells containing the recombinant nucleic acid molecules; antibodies having binding affinity specifically to PCA3 proteins and polypeptides; hybridomas containing the antibodies; nucleic acid probes for the detection of nucleic acids encoding PCA3 proteins; a method of detecting nucleic acids encoding PCA3 proteins or polypeptides in a sample; kits containing nucleic acid probes or antibodies; bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess, or prognose a mammal afflicted with prostate cancer; therapeutic uses; and methods of preventing prostate cancer in an animal.
FILED Friday, October 30, 2009
APPL NO 12/609483
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551700 Gordon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Gavin J. Gordon (West Newbury, Massachusetts);  Roderick V. Jensen (Pelham, Massachusetts);  Steven R. Gullans (Natick, Massachusetts);  Li-Li Hsiao (Jamaica Plain, Massachusetts);  Raphael Bueno (Brookline, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Wesleyan University (Middletown, Connecticut)
INVENTOR(S) Gavin J. Gordon (West Newbury, Massachusetts);  Roderick V. Jensen (Pelham, Massachusetts);  Steven R. Gullans (Natick, Massachusetts);  Li-Li Hsiao (Jamaica Plain, Massachusetts);  Raphael Bueno (Brookline, Massachusetts)
ABSTRACT The invention provides methods for diagnosing biological states or conditions based on ratios of gene expression data from tissue samples, such as cancer tissue samples. The invention also provides sets of genes that are expressed differentially in malignant pleural mesothelioma. These sets of genes can be used to discriminate between normal and malignant tissues, and between classes of malignant tissues. Accordingly, diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression also are provided.
FILED Monday, July 12, 2010
APPL NO 12/834316
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551714 Jovanovich et al.
FUNDED BY
Department of Homeland Security (DHS)
Homeland Security Advanced Research Projects Agency (HSARPA)
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Stevan Bogdan Jovanovich (Livermore, California);  Iuliu Ioan Blaga (Fremont, California)
ASSIGNEE(S) IntegenX Inc. (Pleasanton, California)
INVENTOR(S) Stevan Bogdan Jovanovich (Livermore, California);  Iuliu Ioan Blaga (Fremont, California)
ABSTRACT Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.
FILED Monday, February 06, 2012
APPL NO 13/367326
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551720 Cao
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Deliang Cao (Chatham, Illinois)
ASSIGNEE(S) The Board of Trustees of Southern Illinois University (Springfield, Illinois)
INVENTOR(S) Deliang Cao (Chatham, Illinois)
ABSTRACT Provided herein are methods and materials for diagnosing a bowel disease in a subject by detecting the presence or absence of a bowel disease marker. A bowel disease marker has been identified as AKR1B10 and may be useful in identifying subjects at risk for bowel disease, predicting bowel disease progression, and assessing a subject's response to therapy.
FILED Friday, October 24, 2008
APPL NO 12/739371
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551726 Morimoto et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Richard I. Morimoto (Evanston, Illinois);  Sandy Westerheide (Evanston, Illinois);  Julius Anckar (Turku, Finland);  Lea Sistonen (Turku, Finland);  Barbara Calamini (Chapel Hill, North Carolina)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Richard I. Morimoto (Evanston, Illinois);  Sandy Westerheide (Evanston, Illinois);  Julius Anckar (Turku, Finland);  Lea Sistonen (Turku, Finland);  Barbara Calamini (Chapel Hill, North Carolina)
ABSTRACT The present invention is directed to methods of modulating HSF1 activity comprising modifying the acetylation of the DNA binding domain of the HSF1.
FILED Tuesday, June 07, 2011
APPL NO 13/155170
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/18
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551739 Shuman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Stewart Shuman (New York, New York)
ASSIGNEE(S) Memorial Sloan-Kettering Cancer Center (New York, New York)
INVENTOR(S) Stewart Shuman (New York, New York)
ABSTRACT This invention provides a modified vaccinia topoisomerase enzyme containing an affinity tag which is capable of facilitating purification of protein-DNA complexes away from unbound DNA. This invention further provides a modified sequence specific topoisomerase enzyme. This invention provides a method of ligating duplex DNAs, a method of molecular cloning of DNA, a method of synthesizing polynucleotides, and a method of gene targeting. Lastly, this invention provides a recombinant DNA molecule composed of segments of DNA which have been joined ex vivo by the use of a sequence specific topoisomerase and which has the capacity to transform a suitable host cell comprising a DNA sequence encoding polypeptide activity.
FILED Monday, August 20, 2007
APPL NO 11/894817
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551756 Smith et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Gale Smith (Rockville, Maryland);  Peter Pushko (Frederick, Maryland)
ASSIGNEE(S) Novavax, Inc. (Rockville, Maryland)
INVENTOR(S) Gale Smith (Rockville, Maryland);  Peter Pushko (Frederick, Maryland)
ABSTRACT This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
FILED Tuesday, January 19, 2010
APPL NO 12/689826
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/235.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551768 Kolpashchikov
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Dmitry Kolpashchikov (Winter Park, Florida)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Dmitry Kolpashchikov (Winter Park, Florida)
ABSTRACT A probe that changes solution color in the presence of only one of the two DNA sequences, which differ by a single nucleotide, is reported. The probe consists of two oligodeoxyribonucleotides, which form a hydrogen peroxidase-like DNA enzyme when hybridized to the abutting fragments of the complementary analyte. The active peroxidase catalyses oxidation of colorless substrates to the colored products. The probe allows visual detection of a mutation in Alzheimer's disease-related DNA.
FILED Friday, November 20, 2009
APPL NO 13/130536
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/287.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551772 Iadonato et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Shawn P Iadonato (Seattle, Washington);  Charles L Magness (Seattle, Washington);  Gary Rosenberg (Danbury, Connecticut);  Christina A Scherer (Seattle, Washington);  Thierry Guillaudeux (Rennes, France)
ASSIGNEE(S) Kineta Two, LLC (Seattle, Washington)
INVENTOR(S) Shawn P Iadonato (Seattle, Washington);  Charles L Magness (Seattle, Washington);  Gary Rosenberg (Danbury, Connecticut);  Christina A Scherer (Seattle, Washington);  Thierry Guillaudeux (Rennes, France)
ABSTRACT A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided.
FILED Tuesday, November 22, 2011
APPL NO 13/302081
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551776 Wang
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Zhao Yi Wang (Bellevue, Nebraska)
ASSIGNEE(S) Creighton University (Omaha, Nebraska)
INVENTOR(S) Zhao Yi Wang (Bellevue, Nebraska)
ABSTRACT The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-α36 activity. The invention further provides methods for identifying agents that bind to such polypeptides, methods for detecting such polypeptides, and methods for altering the activity of such polypeptides. Also provided are antibodies that specifically bind to an amino acid sequence depicted at SEQ ID NO:1, or an immunogenic fragment thereof, and methods for making and using such antibodies.
FILED Tuesday, August 07, 2012
APPL NO 13/568144
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551780 Agrawal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Deepak Kumar Agrawal (Tampa, Florida);  Warren Jackson Pledger (Odessa, Florida);  Jonathan A. Kluft (Tampa, Florida);  Asha Agrawal (Tampa, Florida)
ASSIGNEE(S) H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida);  University of South Florida (Tampa, Florida);  Proteacel, LLC (Tampa, Florida)
INVENTOR(S) Deepak Kumar Agrawal (Tampa, Florida);  Warren Jackson Pledger (Odessa, Florida);  Jonathan A. Kluft (Tampa, Florida);  Asha Agrawal (Tampa, Florida)
ABSTRACT The subject invention concerns an electroporation buffer that allows for enhanced transfection efficiency and cell viability of cells during application of an electric current. Buffers of the invention provide for maximum transfer of target particles into cells while maintaining the health and growth potential of the cell population. Compositions of the invention comprise electroporation buffers of approximately physiological ionic strength and pH, and having serum or purified proteins, such as serum albumin, added thereto. The subject invention is suitable for use with any cell type. The subject invention also concerns methods of electroporation using an electroporation buffer of the invention.
FILED Monday, February 02, 2009
APPL NO 12/364409
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551781 Rome et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) Leonard H. Rome (Tarzana, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Glen R. Nemerow (La Jolla, California);  Cheng-Yu Lai (La Jolla, California);  Christopher M. Wiethoff (Downers Grove, Illinois);  Mu Ri Han (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Leonard H. Rome (Tarzana, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Glen R. Nemerow (La Jolla, California);  Cheng-Yu Lai (La Jolla, California);  Christopher M. Wiethoff (Downers Grove, Illinois);  Mu Ri Han (Los Angeles, California)
ABSTRACT The invention relates to compositions of vault complexes containing recombinant membrane lytic proteins, such as an adenovirus protein VI lytic domain, and methods of using the vault complexes to facilitate delivery and entry of a biomolecule into a cell or subject.
FILED Friday, November 19, 2010
APPL NO 12/950994
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551782 Zon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Leonard I. Zon (Wellesley, Massachusetts);  Trista E. North (Newton Center, Massachusetts);  Wolfram Goessling (Chestnut Hill, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Leonard I. Zon (Wellesley, Massachusetts);  Trista E. North (Newton Center, Massachusetts);  Wolfram Goessling (Chestnut Hill, Massachusetts)
ABSTRACT The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that either increase HSC numbers or decrease HSC numbers as desired by a particular indication. For example, HSC modulators found to increase HSC numbers include prostaglandin E2 (PGE2) and agents that stimulate the PGE2 pathway. Conversely, HSC modulators that prevent PGE2 synthesis decrease HSC numbers. HCS modulators may be used in vitro, in vivo, or ex vivo.
FILED Tuesday, March 27, 2012
APPL NO 13/431534
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551936 Kwak et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Larry W. Kwak (Houston, Texas);  Bira Arya (Baltimore, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Larry W. Kwak (Houston, Texas);  Bira Arya (Baltimore, Maryland)
ABSTRACT The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a defensin fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection.
FILED Tuesday, November 22, 2011
APPL NO 13/303081
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551949 Toll et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Lawrence R. Toll (Redwood City, California);  David C. Yeomans (Sunnyvale, California);  Martin S. Angst (Palo Alto, California);  Daniel I. Jacobs (Mountain View, California)
ASSIGNEE(S) Nocicepta LLC (Wilmington, Delaware)
INVENTOR(S) Lawrence R. Toll (Redwood City, California);  David C. Yeomans (Sunnyvale, California);  Martin S. Angst (Palo Alto, California);  Daniel I. Jacobs (Mountain View, California)
ABSTRACT The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.
FILED Tuesday, July 27, 2010
APPL NO 12/844721
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/18.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551964 Ross et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) David Ross (Boulder, Colorado);  David Siegel (Denver, Colorado);  Wenchang Guo (Elk Grove, California);  Christopher J. Moody (Leeds, United Kingdom);  Christopher S. P. McErlean (Eden's Landing, Australia)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) David Ross (Boulder, Colorado);  David Siegel (Denver, Colorado);  Wenchang Guo (Elk Grove, California);  Christopher J. Moody (Leeds, United Kingdom);  Christopher S. P. McErlean (Eden's Landing, Australia)
ABSTRACT The invention provides 19-substituted geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents useful for the treatment of, and/or the amelioration of symptoms of, cancer and other proliferative tissue disorders.
FILED Friday, August 22, 2008
APPL NO 12/673996
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/34
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551969 Pagano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Michele Pagano (New York, New York);  Luca Busino (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Michele Pagano (New York, New York);  Luca Busino (New York, New York)
ABSTRACT Cdc25A is herein identified as a substrate for β-TrCP1- or β-TrCP2-mediated ubiquitination and subsequent degradation via the ubiquitin-proteasome pathway. In particular, it has been found that interfering with β-TrCP expression or function, or increasing β-TrCP degradation, leads to accumulation of Cdc25A in a cell. Since degradation of Cdc25A is a key feature of the response to DNA damage, leading to a stall in the cell cycle during which the cell can repair the damage, Cdc25A accumulation can abolish this response, thereby sensitizing the cell to DNA damage. Described herein are assays for identifying β-TrCP inhibitors, and method of using such inhibitors for modulating Cdc25A degradation, sensitization of tumor cells, and as adjuvants in cancer therapy based on DNA damaging agents.
FILED Tuesday, October 14, 2008
APPL NO 12/251082
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551976 Franz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Katherine J. Franz (Durham, North Carolina);  Filip Kielar (Malá Morávka, Czech Republic)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Katherine J. Franz (Durham, North Carolina);  Filip Kielar (Malá Morávka, Czech Republic)
ABSTRACT The present invention provides compounds of Formula I along with compositions containing the same and methods of use thereof in treating oxidative stress.
FILED Wednesday, August 01, 2012
APPL NO 13/564081
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/64
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551996 Stehouwer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Jeff Stehouwer (Atlanta, Georgia);  Mark Goodman (Atlanta, Georgia);  Clint Kilts (Little Rock, Arkansas);  Charles Nemeroff (Coconut Grove, Florida)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Jeff Stehouwer (Atlanta, Georgia);  Mark Goodman (Atlanta, Georgia);  Clint Kilts (Little Rock, Arkansas);  Charles Nemeroff (Coconut Grove, Florida)
ABSTRACT Briefly described, embodiments of this disclosure include compounds as described herein, labeled compounds as described herein, pharmaceutical composition including compounds described herein, methods of imaging, method of forming a compound as described herein, and the like. In particular, embodiments of the disclosure include a series of triamino-pyridine derivatives and labeled triamino-pyridine derivatives, methods of synthesizing these compounds, intermediate compounds, methods of treatment using these compounds, methods of imaging, diagnosing, localizing, monitoring, and/or assessing a condition (e.g., corticotropin releasing factor type-1 (CRF1)) and/or related biological events, using triamino-pyridine derivatives, and the like. In addition, the present disclosure includes compositions (e.g., labeled triamino-pyridine derivatives that are ligands for the CRF1 receptor) used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging or SPECT imaging).
FILED Friday, March 12, 2010
APPL NO 13/201485
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/249
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551997 Srivastava et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Satish K. Srivastava (Galveston, Texas);  Kota V. Ramana (Galveston, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Satish K. Srivastava (Galveston, Texas);  Kota V. Ramana (Galveston, Texas)
ABSTRACT Provided herein are methods of treating a pathophysiological state or symptoms thereof resulting from aldose reductase-mediated signaling in a cytotoxic pathway in a subject using an inhibitor of aldose reductase. Particularly, specific inhibitors may be a small-interfering RNA (siRNA) or may be inhibitors of glutathione-aldehyde binding to aldose reductase which are designed via at least computer modeling of the ternary AR:NADPH:DCEG structure. Also, methods of treating a cancer or suppressing metastasis thereof using the siRNAs and aldose reductase inhibitors are provided.
FILED Friday, June 29, 2007
APPL NO 12/308915
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/252.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552014 Gangjee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Aleem Gangjee (Allison Park, Pennsylvania);  Larry H. Matherly (Farmington Hills, Michigan)
ASSIGNEE(S) Duquesne University of The Holy Ghost (Pittsburgh, Pennsylvania);  Wayne State University (Detroit, Michigan)
INVENTOR(S) Aleem Gangjee (Allison Park, Pennsylvania);  Larry H. Matherly (Farmington Hills, Michigan)
ABSTRACT A method for treating cancer tumors, particularly ovarian cancer tumors, is described, where fused cyclic pyrimidine having a cancer treating ability is selectively delivered to an FR expressing cancerous tumor.
FILED Monday, July 30, 2012
APPL NO 13/561657
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/265.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552018 Hurley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Laurence H. Hurley (Tucson, Arizona);  Daruka Mahadevan (Tucson, Arizona);  David J. Bearss (Cedar Hills, Utah);  Hariprasad Vankayalapati (Draper, Utah);  Sridevi Bashyam (Bangalore, India);  Steven L. Warner (Sandy, Utah);  James Welsh (Oro Valley, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona);  Astex Pharmaceutials, Inc. (Dublin, California)
INVENTOR(S) Laurence H. Hurley (Tucson, Arizona);  Daruka Mahadevan (Tucson, Arizona);  David J. Bearss (Cedar Hills, Utah);  Hariprasad Vankayalapati (Draper, Utah);  Sridevi Bashyam (Bangalore, India);  Steven L. Warner (Sandy, Utah);  James Welsh (Oro Valley, Arizona)
ABSTRACT Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure:
including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from:
and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
FILED Friday, March 18, 2011
APPL NO 13/051790
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/267
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552050 Cantley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Lewis C. Cantley (Cambridge, Massachusetts);  Matthew G. Vander Heiden (Somerville, Massachusetts);  Heather R. Christofk (Carlsbad, California)
ASSIGNEE(S) Beth Israel Deaconess Medical Center (Boston, Massachusetts)
INVENTOR(S) Lewis C. Cantley (Cambridge, Massachusetts);  Matthew G. Vander Heiden (Somerville, Massachusetts);  Heather R. Christofk (Carlsbad, California)
ABSTRACT The invention described herein features methods, compositions, and kits for the use of activators of PKM2 for the treatment, prevention, or amelioration of diseases related to PKM2 function, including, e.g., cancer, diabetes, atherosclerosis, restenosis, obesity, autoimmune disorders, and proliferative disorders.
FILED Monday, August 18, 2008
APPL NO 12/672827
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/407
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552059 Andreasson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Katrin Andreasson (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Katrin Andreasson (Stanford, California)
ABSTRACT The present invention provides compositions and methods for treating an ischemic episode using misoprostol alone or in combination with anti-thrombotic agents.
FILED Tuesday, September 18, 2012
APPL NO 13/621977
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/530
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552061 Hochberg
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Richard Hochberg (Guilford, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Richard Hochberg (Guilford, Connecticut)
ABSTRACT The present invention relates to antiandrogenic compounds which may be administered for the treatment of androgen excess in the skin and by way of consequence, the treatment of acne, baldness or hirsuitism in subject or patient. These compounds have the general chemical structure (I, II, III or IV).
FILED Friday, May 02, 2008
APPL NO 12/450862
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/542
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552067 Verkman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Alan S. Verkman (San Francisco, California);  Nitin D. Sonawane (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alan S. Verkman (San Francisco, California);  Nitin D. Sonawane (San Francisco, California)
ABSTRACT Provided herein are bioactive agents comprising a compound that inhibits the ion transport activity of a cystic fibrosis transmembrane conductance regulator (CFTR) and that is linked to a macromolecule that interacts with a cell that expresses CFTR. The bioactive agents described herein are useful for treating diseases, disorders, and sequelae of diseases, disorders, and conditions that are associated with aberrantly increased CFTR activity, for example, secretory diarrhea.
FILED Wednesday, December 19, 2007
APPL NO 11/960521
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/639
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552100 Song et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Jie Song (Shrewsbury, Massachusetts);  Eduardo Saiz (Berkeley, California);  Carolyn R. Bertozzi (Berkeley, California);  Antoni P. Tomsia (Pinole, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jie Song (Shrewsbury, Massachusetts);  Eduardo Saiz (Berkeley, California);  Carolyn R. Bertozzi (Berkeley, California);  Antoni P. Tomsia (Pinole, California)
ABSTRACT A composite having a flexible hydrogel polymer formed by mixing an organic phase with an inorganic composition, the organic phase selected from the group consisting of a hydrogel monomer, a crosslinker, a radical initiator, and/or a solvent. A polymerization mixture is formed and polymerized into a desired shape and size.
FILED Wednesday, February 22, 2006
APPL NO 11/817016
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
524/417
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552169 Dietrich et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Jeffrey A. Dietrich (San Francisco, California);  Jay D. Keasling (Berkeley, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jeffrey A. Dietrich (San Francisco, California);  Jay D. Keasling (Berkeley, California)
ABSTRACT The present invention provides for a system comprising a BmoR transcription factor, a σ54-RNA polymerase, and a pBMO promoter operatively linked to a reporter gene, wherein the pBMO promoter is capable of expression of the reporter gene with an activated form of the BmoR and the σ54-RNA polymerase.
FILED Monday, April 26, 2010
APPL NO 12/767649
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552171 Tuschl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Thomas Tuschl (Goettingen, Germany);  Phillip D. Zamore (Northborough, Massachusetts);  Phillip A. Sharp (Newton, Massachusetts);  David P. Bartel (Brookline, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts);  Whitehead Insititute for Biomedical Research (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  Max-Planck-Gesellschaft zur Föderung der Wissenschaften E.V. (Munich, Germany)
INVENTOR(S) Thomas Tuschl (Goettingen, Germany);  Phillip D. Zamore (Northborough, Massachusetts);  Phillip A. Sharp (Newton, Massachusetts);  David P. Bartel (Brookline, Massachusetts)
ABSTRACT The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications.
FILED Monday, October 04, 2010
APPL NO 12/897740
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552176 Thorson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Jon S. Thorson (Lexington, Kentucky);  Randal D. Goff (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Jon S. Thorson (Lexington, Kentucky);  Randal D. Goff (Madison, Wisconsin)
ABSTRACT A library of glycosylated chlorambucil analogs which are useful as anti-tumor and/or anti-metastatic agents is disclosed. The glycosylated chlorambucil analogs have the general formula
wherein
represents a reducing sugar moiety.
FILED Monday, October 17, 2011
APPL NO 13/274814
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Organic compounds
536/29.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552208 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Richard E. Lee (Cordova, Tennessee);  Julian Gregston Hurdle (Germantown, Tennessee);  Raghunandan Yendapally (Longmeadow, Massachusetts)
ASSIGNEE(S) University of Tennesseee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Richard E. Lee (Cordova, Tennessee);  Julian Gregston Hurdle (Germantown, Tennessee);  Raghunandan Yendapally (Longmeadow, Massachusetts)
ABSTRACT Tetramic acid analogues of Formula I and Formula II have antibacterial activity, primarily against gram-positive bacteria, and are iron chelators.
FILED Monday, September 08, 2008
APPL NO 12/231915
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
548/544
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552242 Hoveyda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Amir H. Hoveyda (Lincoln, Massachusetts);  Simon J. Meek (Newtonville, Massachusetts);  Robert V. O'Brien (Brighton, Massachusetts);  Josep Llaveria Cros (Tarragona, Spain);  Richard R. Schrock (Winchester, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S) Amir H. Hoveyda (Lincoln, Massachusetts);  Simon J. Meek (Newtonville, Massachusetts);  Robert V. O'Brien (Brighton, Massachusetts);  Josep Llaveria Cros (Tarragona, Spain);  Richard R. Schrock (Winchester, Massachusetts)
ABSTRACT The present invention generally relates to methods for performing metathesis reactions, including cross-metathesis reactions. Methods described herein exhibit enhanced activity and stereoselectivity, relative to known methods, and are useful in the synthesis of a large assortment of biologically and therapeutically significant agents.
FILED Tuesday, February 08, 2011
APPL NO 13/023400
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Chemistry of hydrocarbon compounds
585/646
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552254 Wiles et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Michael V. Wiles (Mount Desert, Maine);  Robert Taft (Southwest Harbor, Maine);  Eva M. Eicher (Seal Cove, Maine);  Shannon Byers (Lamoine, Maine)
ASSIGNEE(S) The Jackson Laboratory (Bar Harbor, Maine)
INVENTOR(S) Michael V. Wiles (Mount Desert, Maine);  Robert Taft (Southwest Harbor, Maine);  Eva M. Eicher (Seal Cove, Maine);  Shannon Byers (Lamoine, Maine)
ABSTRACT The present invention provides novel methods of maintaining genetic stability of non-human animal inbred strains. In the methods, pedigree-tracked cryopreserved embryos or gametes or pre-gametes derived from a foundation colony are produced and used to re-establish the foundation colony at appropriate intervals.
FILED Monday, October 26, 2009
APPL NO 12/606047
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/21
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08553219 Patil et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Chetan A. Patil (Nashville, Tennessee);  Anita Mahadevan-Jansen (Nashville, Tennessee);  Antonius Gerardus Johannes Maria Van Leeuwen (Bussum, Netherlands);  Jeroen Kalkman (Utrecht, Netherlands)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee);  Academisch Medisch Centrum Bu de Universiteit van Amsterdam (Amsterdam, Netherlands)
INVENTOR(S) Chetan A. Patil (Nashville, Tennessee);  Anita Mahadevan-Jansen (Nashville, Tennessee);  Antonius Gerardus Johannes Maria Van Leeuwen (Bussum, Netherlands);  Jeroen Kalkman (Utrecht, Netherlands)
ABSTRACT An apparatus includes first and second light sources for respectively generating broadband and monochromatic lights, a beamsplitter optically coupled to the first light source for splitting the broadband light into a reference light and a sample light, a reference arm optically coupled to the beamsplitter for receiving the reference light and returning the received reference light into the beamsplitter, a sample arm optically coupled to the beamsplitter and the second light source for combining the sample and monochromatic lights, delivering the combined light to the target of interest, collecting a backscattering light and a Raman scattering light generated from interaction of the combined light with the target of interest, returning the backscattering light into the beamsplitter so as to generate an interference signal between the returned backscattering light and the returned reference light in the beamsplitter, and directing the Raman scattering light in an output optical path.
FILED Monday, January 24, 2011
APPL NO 13/012529
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/301
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08553337 Webb et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Watt W. Webb (Ithaca, New York);  Chris Xu (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Watt W. Webb (Ithaca, New York);  Chris Xu (Ithaca, New York)
ABSTRACT Embodiments of the invention include an optical system and an optical system module, coupled to a distal end of a fluorescence emission endoscope apparatus, an optical waveguide-based fluorescence emission endoscopy system, and a method for remotely-controlled, multi-magnification imaging of a target or fluorescence emission collection from a target with a fluorescence emission endoscope apparatus. An exemplary system includes an objective lens disposed in a distal end of an endoscope apparatus. The lens is adapted to transmit both a visible target illumination and a fluorescence-emission-inducing target illumination as well as fluorescence-emission and visible light from the target. The system can thus simultaneously provide low magnification, large field of view imaging and high magnification, high-resolution multiphoton imaging with a single lens system.
FILED Wednesday, November 12, 2008
APPL NO 12/742562
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/722
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08554305 Tailor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Dharmesh R. Tailor (Voorhees, New Jersey);  James E. Baumgardner (Folsom, Pennsylvania);  Ravinder Reddy (Gladwyne, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Dharmesh R. Tailor (Voorhees, New Jersey);  James E. Baumgardner (Folsom, Pennsylvania);  Ravinder Reddy (Gladwyne, Pennsylvania)
ABSTRACT Prior approaches have delivered 17O2 to a subject by inhalation, but the relationship between local signal changes and metabolism has been complicated by H217O created in non-cerebral tissues. During a brief pulse of 17O2 inhalation, this arterial input function for H217O is negligible due to convective transport delays. Additional delays in the arterial input function due to restricted diffusion of water makes pulsed inhalation of 17O2 even more effective. Accordingly, ventilator system are provided to deliver 17O2 as a brief pulse to a subject. Subsequent MR imaging demonstrates delayed appearance of H217O in the cerebral ventricles, suggesting that the arterial input function of H217O is delayed by restricted water diffusion in addition to convective transit delays. Delivery as a brief pulse therefore offers significant advantages in relating MR signal changes directly to metabolism.
FILED Friday, July 18, 2008
APPL NO 12/669854
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Surgery
6/420
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08554328 Faraji et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Second Sight Medical Products, Inc. (San Fernando, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Boozarjomehr Faraji (Valencia, California);  Kevin Jun Ha (Los Angeles, California);  Neil Hamilton Talbot (La Cresenta, California);  James Singleton Little (Newhall, California);  Robert J. Greenberg (Los Angeles, California)
ABSTRACT The present invention is a non-destructive method of inspecting a bond, particularly a braze bond, in a hermetic package. The invention involves a unique hermetic package design adapted for ultrasonic inspection and a method of inspecting the package. This package and non-destructive inspection process are particularly useful in implantable neural stimulators such as visual prostheses.
FILED Tuesday, January 29, 2013
APPL NO 13/752636
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/54
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08554488 Wigler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Michael H. Wigler (Cold Spring Harbor, New York);  Lakshmi Muthuswamy (Toronto, Canada);  Jonathan Sebat (San Diego, California)
ASSIGNEE(S) Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
INVENTOR(S) Michael H. Wigler (Cold Spring Harbor, New York);  Lakshmi Muthuswamy (Toronto, Canada);  Jonathan Sebat (San Diego, California)
ABSTRACT The present invention provides methods and compositions related to genomic profiling, and in particular, to assigning probabilistic measure of clinical outcome for a patient having a disease or a tumor using segmented genomic profiles such as those produced by representational oligonucleotide microarray analysis (ROMA).
FILED Thursday, December 14, 2006
APPL NO 11/639712
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 1/6886 (20130101)

Electric Digital Data Processing
G06F 19/18 (20130101)
G06F 19/34 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08554490 Tang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Mathematical Sciences (DMS)
APPLICANT(S) Dalin Tang (Shrewsbury, Massachusetts);  Zhongzhao Teng (Lianjiang, China PRC)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Dalin Tang (Shrewsbury, Massachusetts);  Zhongzhao Teng (Lianjiang, China PRC)
ABSTRACT A computer system and method are disclosed for automatically generating a vascular model of a blood vessel to support, for example, identification of mechanical factors corresponding to the blood vessel. The method includes interpolating data points corresponding to a contour of the blood vessel; generating a structural model representing three-dimensional structural characteristics of the blood vessel based on interpolated contours; generating a fluid model representing three-dimensional characteristics of fluid flow within the vessel; and generating a vascular model based on the structural model and the fluid model. The method may also include performing a mechanical analysis of the vascular model to identify a mechanical factor associated with the vessel, for example, a factor associated with a potential plaque rupture within the vessel. Embodiments of the invention are applicable to the diagnosis, assessment, or treatment of cardiovascular diseases.
FILED Thursday, February 18, 2010
APPL NO 13/201946
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08554509 Crisco, III et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Joseph J. Crisco, III (Providence, Rhode Island);  Richard M. Greenwald (Norwich, Vermont)
ASSIGNEE(S) Riddell, Inc. (Rosemont, Illinois)
INVENTOR(S) Joseph J. Crisco, III (Providence, Rhode Island);  Richard M. Greenwald (Norwich, Vermont)
ABSTRACT A system and method for determining the magnitude of linear and rotational acceleration of and direction of impact to a body part. In one version, protective sports equipment is worn by a player engaged in a sporting activity. The equipment includes a padding assembly that resides against the player during the sporting activity; a band removably positioned within the padding assembly, the band including a control unit having a plurality of sensing devices, a processor and a wireless transmitter that collectively interact to transmit data detected by the sensing devices, the control unit further having an encoder that encodes data from the sensing devices with a unique identifier prior to transmission.
FILED Wednesday, November 24, 2004
APPL NO 10/997832
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/141
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE44533 Timmins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Graham Timmins (Albuquerque, New Mexico);  Vojo P. Deretic (Placitas, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico)
INVENTOR(S) Graham Timmins (Albuquerque, New Mexico);  Vojo P. Deretic (Placitas, New Mexico)
ABSTRACT The present invention relates to methods for detecting P aeruginosa infection and bacterial burden in the lungs of patients who are at risk for P. aeruginosa infections, especially including patients with Cystic Fibrosis (CF). The present method provides numerous tests (breath, blood, urine) which are readily administered to a patient that will sensitively and specifically detect the presence and extent of lung infection P. aeruginosa (both mucoid and non-mucoid), and allow monitoring of bacterial load as a parameter in monitoring treatment.
FILED Wednesday, May 09, 2012
APPL NO 13/467514
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Surgery
6/532
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 08549920 Maguire et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Jason M. Maguire (Middletown, Rhode Island);  Gregory H. Ames (Wakefield, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jason M. Maguire (Middletown, Rhode Island);  Gregory H. Ames (Wakefield, Rhode Island)
ABSTRACT An accelerometer has a substantially linear strain sensor with a transducer joined to the strain sensor. The transducer has a base that provides rigidity perpendicular to a preferred measurement direction. A plurality of outer flaps are joined to the base supporting the strain sensor. The outer flaps are capable of translating acceleration in the predefined direction to strain in the strain sensor. Two centermost flaps are positioned on either side of the center line of the transducer. Struts are joined between a lower portion of one the centermost flap and an uppermost portion of the nearest outer flap. The struts enhance strain by linking outer flap motion to the centermost flaps. Bridges are joined between each two adjacent outer flaps supporting the strain sensor.
FILED Tuesday, September 22, 2009
APPL NO 12/291048
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring and testing
073/514.160
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08550001 Rastegar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Jahangir S. Rastegar (Stony Brook, New York);  Richard T. Murray (Patchogue, New York);  Jacques Fischer (Sound Beach, New York)
ASSIGNEE(S) Omnitek Partners LLC (Ronkonkoma, New York)
INVENTOR(S) Jahangir S. Rastegar (Stony Brook, New York);  Richard T. Murray (Patchogue, New York);  Jacques Fischer (Sound Beach, New York)
ABSTRACT An inertial igniter including: a body having a base and three or more posts, each post having a hole; a locking ball corresponding to each post, wherein a portion of the locking balls are disposed in the hole; a striker mass movably disposed relative to the posts and having a surface corresponding to the posts, the striker mass further having a concave portion corresponding to the locking balls, wherein a second portion of each locking ball is disposed in a corresponding concave portion for retaining the striker mass relative to the posts; a collar movable relative to the posts; and a biasing element for biasing the collar in a first position which retains the striker mass, the biasing element permitting movement of the collar to a second position to release the striker mass relative to the posts upon a predetermined acceleration profile.
FILED Tuesday, July 13, 2010
APPL NO 12/835709
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/216
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08550004 Woo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Timothy Woo (Flushing, New York);  Leon Moy (Montclair, New Jersey);  Bishara Elmasri (Landing, New Jersey);  Christina Morales (Mine Hill, New Jersey);  Alan N. Cohen (Wharton, New Jersey);  Daniel Lee Prillaman (Montclair, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Timothy Woo (Flushing, New York);  Leon Moy (Montclair, New Jersey);  Bishara Elmasri (Landing, New Jersey);  Christina Morales (Mine Hill, New Jersey);  Alan N. Cohen (Wharton, New Jersey);  Daniel Lee Prillaman (Montclair, New Jersey)
ABSTRACT An IM type steel cartridge whose base contains a central bore there through—within which bore is a steel base plug holding a primer cup, the base plug being held in place by a low melt, 220 to 250 degree F. melt eutectic solder—wherein, if the cartridge is subjected to an unforeseen thermal or kinetic event, the solder will melt, the base plug ejected, and the propellant will vent rather than explode. The solder bond between the base plug and the cartridge case within which it is held is capable of resisting the from about 72,000, to up to 90,000 psi, force generated within the firing chamber of the weapon by the ignition and firing of the cartridge.
FILED Monday, June 04, 2012
APPL NO 13/487688
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/430
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08550038 Marlenee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Alyssa Marlenee (St. Louis Park, Minnesota);  Arthur J. Punyko (St. Paul, Minnesota);  Leo T. Steffl (Minneapolis, Minnesota);  Michael A. Fedewa (Isanti, Minnesota);  Lee Midlo (Isanti, Minnesota);  Daniel Woody (Troy, Michigan)
ASSIGNEE(S) Cummins Power Generation IP, Inc. (Minneapolis, Minnesota)
INVENTOR(S) Alyssa Marlenee (St. Louis Park, Minnesota);  Arthur J. Punyko (St. Paul, Minnesota);  Leo T. Steffl (Minneapolis, Minnesota);  Michael A. Fedewa (Isanti, Minnesota);  Lee Midlo (Isanti, Minnesota);  Daniel Woody (Troy, Michigan)
ABSTRACT A system includes a genset having an engine, an AC generator, and a radiator thermally coupled to the engine. The system includes an electric variable speed fan having an outlet flow, where the outlet flow passes at least partially through the radiator. The system includes a controller structured to functionally execute certain operations for cooling the genset. The controller interprets a genset identification parameter and selects a cooling algorithm from a predetermined set of cooling algorithms according to the genset identification parameter. The controller further interprets genset operating conditions according to the cooling algorithm, and provides a cooling fan command in response to the genset operating conditions and the cooling algorithm. The electric variable speed fan is responsive to the cooling fan command.
FILED Tuesday, October 05, 2010
APPL NO 12/924774
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Internal-combustion engines
123/41.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08550145 Wood et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
APPLICANT(S) Thomas D. Wood (Houghton, Michigan);  Neil Anderson (Calumet, Michigan);  Andrew Halonen (Calumet, Michigan)
ASSIGNEE(S) Century, Inc. (Traverse City, Michigan)
INVENTOR(S) Thomas D. Wood (Houghton, Michigan);  Neil Anderson (Calumet, Michigan);  Andrew Halonen (Calumet, Michigan)
ABSTRACT A method of forming a metal matrix composite (MMC),such as a brake drum, by impregnating a preform, which is formed of ceramic particles and ceramic fibers, with a support element, such as a metal. The MMC has a wear surface defined by both the preform and the support element.
FILED Tuesday, September 13, 2011
APPL NO 13/231374
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal founding
164/97
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US 08550702 Campbell et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Levi A. Campbell (Poughkeepsie, New York);  Thomas C. Long (Poughkeepsie, New York);  Robert B. Schlak (Hyde Park, New York);  Peter A. Wendling (Poughkeepsie, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Levi A. Campbell (Poughkeepsie, New York);  Thomas C. Long (Poughkeepsie, New York);  Robert B. Schlak (Hyde Park, New York);  Peter A. Wendling (Poughkeepsie, New York)
ABSTRACT A calibrated airflow sensor and monitoring method are provided. The monitoring method which includes: providing an airflow sensor positioned within an electronic system to be at least partially air-cooled, the airflow sensor including at least one temperature sensor and a heater associated with one temperature sensor of the at least one temperature sensor; calibrating, with the airflow sensor positioned within the electronic system, a duty cycle for use in powering the heater associated with the one temperature sensor; and providing a controller configured to use the calibrated duty cycle in powering the heater of the temperature sensor during airflow monitoring of the electronic system, and to obtain a hot temperature (Thot) reading from the one temperature sensor having the associated heater, and to determine, based at least in part on the hot temperature (Thot) reading, whether to issue an airflow warning.
FILED Monday, October 31, 2011
APPL NO 13/285014
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Thermal measuring and testing
374/1
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US 08550750 Evans et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Corps of Engineers (USACE)
Environmental Security Technology Certification Program (ESTCP)
APPLICANT(S) Patrick J. Evans (Seattle, Washington);  Karl Hopfensperger (Birmingham, Alabama)
ASSIGNEE(S) CDM Smith Inc. (Cambridge, Massachusetts)
INVENTOR(S) Patrick J. Evans (Seattle, Washington);  Karl Hopfensperger (Birmingham, Alabama)
ABSTRACT A method is provided for stimulating anaerobic degradation of a subsurface contaminant, comprising the steps of vaporizing liquefied petroleum gas (LPG) to form a treating gas and directing the treating gas to at least one subsurface injection site that includes the subsurface contaminant; wherein the treating gas stimulates anaerobic degradation of at least a portion of the subsurface contaminant.
FILED Thursday, May 07, 2009
APPL NO 12/991037
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Hydraulic and earth engineering
45/128.750
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US 08551268 Yalamanchili et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Rao Yalamanchili (Flanders, New Jersey);  John Hirlinger (Hackettstown, New Jersey);  Christopher Csernica (Port Murray, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Rao Yalamanchili (Flanders, New Jersey);  John Hirlinger (Hackettstown, New Jersey);  Christopher Csernica (Port Murray, New Jersey)
ABSTRACT Improved electric primer compositions, structures, and methods that are compatible with existing munitions and in particular an exemplary electric primer composition including carbon nanotubes along with energetic primer mixture(s) and an exemplary primer structure including layers of energetic materials wherein a layer exhibiting the most energetic character is positioned proximate to a primer button. Alternative embodiments include both conductive and non-conductive layers.
FILED Tuesday, August 14, 2012
APPL NO 13/550751
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosive and thermic compositions or charges
149/109.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551287 Zaldivar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) Rafael J. Zaldivar (Huntington Beach, California);  James P. Nokes (Torrance, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Rafael J. Zaldivar (Huntington Beach, California);  James P. Nokes (Torrance, California)
ABSTRACT A hybrid adhesive incorporating cyanate ester and/or epoxy materials and utilizing atmospheric plasma treatment provides stronger, more reliable joints in structural composite parts.
FILED Sunday, October 03, 2010
APPL NO 12/896905
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/330
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US 08551407 Friedrich et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Craig Friedrich (Houghton, Michigan);  Donald Lueking (Houghton, Michigan);  Mark Griep (Houghton, Michigan)
ASSIGNEE(S) Michigan Technological University (Houghton, Michigan)
INVENTOR(S) Craig Friedrich (Houghton, Michigan);  Donald Lueking (Houghton, Michigan);  Mark Griep (Houghton, Michigan)
ABSTRACT A sensor comprising a membrane containing bacteriorhodopsin. In one embodiment, the sensor comprises a layer of purple membrane between a first and a second electrode, wherein the electrodes are connected to a circuit such that a signal is produced when a charge is transferred across the membrane. In another embodiment, the sensor comprises a field effect transistor with a layer of purple membrane deposited on the gate. The layer of purple membrane may be further functionalized by adding fluorophores to the layer of purple membrane. The fluorophores may be deposited adjacent to the layer of purple membrane, or the fluorophores may be attached to the layer of purple membrane with linkages. The fluorophores or linkages between the fluorophores and the purple membrane may be functionalized with receptors to produce sensors for targeted chemical or biological species.
FILED Monday, December 01, 2008
APPL NO 12/325718
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/82.60
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US 08551441 Srinivasan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Raghavan Srinivasan (Xenia, Ohio);  Jonathan E. Spowart (Dayton, Ohio);  Nicholas Gothard (Beavercreek, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Raghavan Srinivasan (Xenia, Ohio);  Jonathan E. Spowart (Dayton, Ohio);  Nicholas Gothard (Beavercreek, Ohio)
ABSTRACT New methods for improving thermoelectric properties of bismuth telluride based materials are described. Constrained deformation, such as by canned/sandwich, or encapsulated, rolling and plane strain channel die compression, particularly at temperatures above 80% of the melting point of the material on an absolute temperature scale, changes the crystallographic texture and grain size to desirably increase the values of both the thermoelectric power factor and the thermoelectric figure of merit ZT for the material.
FILED Friday, May 11, 2012
APPL NO 13/470170
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/508
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551489 Moussa et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Omar Moussa (Charleston, South Carolina);  Dennis K. Watson (Charleston, South Carolina);  Perry V. Halushka (Charleston, South Carolina)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Omar Moussa (Charleston, South Carolina);  Dennis K. Watson (Charleston, South Carolina);  Perry V. Halushka (Charleston, South Carolina)
ABSTRACT Methods for the treatment of cancers involving dysregulation of thromboxane receptor β (TP-β) are provided, including in certain aspects methods for diagnosing such cancers. Specific cancers included are genitourinary cancers, gastrointestinal cancers and leukemias.
FILED Friday, January 02, 2009
APPL NO 12/811321
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/174.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551513 Jung et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Steven B. Jung (Rolla, Missouri);  Delbert E. Day (Rolla, Missouri)
ABSTRACT A scaffold for implantation into a mammal to facilitate vessel growth in repair, regeneration, and/or proliferation of bodily tissue, where the scaffold is based on a borate, silicate, or phosphate, glass-former and is biodegradable upon implantation in mammals. The scaffold includes one or more trace elements from the group consisting of Cu, F, Fe, Mn, Mo, Ni, Si, Sr, and Zn which are released into the host to support vessel growth. A method involves implantation of such scaffolds.
FILED Monday, October 01, 2012
APPL NO 13/632701
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/423
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551566 Fedynyshyn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Theodore H. Fedynyshyn (Sudbury, Massachusetts);  Richard Kingsborough (North Chelmsford, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Theodore H. Fedynyshyn (Sudbury, Massachusetts);  Richard Kingsborough (North Chelmsford, Massachusetts)
ABSTRACT Methods of directing assembly of materials using a surface-modified substrate are disclosed. A modified surface is created on a substrate by applying a first surface agent to the substrate. Energy is applied to the modified surface to form an imaged surface having an imaged portion and a non-imaged portion. The imaged portion is characterized by a surface energy that is different from the surface energy of the non-imaged portion. For example, the applied energy can remove at least a portion of an attached surface agent from the imaged portion to modify the surface energy. In some preferred embodiments the energy also modifies the surface agent without causing oxidation. To avoid oxidation, for example, the surface modification and/or energy appliement can take place in a low oxygen environment (e.g., having an oxygen content lower than that present in about 0.01 Torr of air). The imaged surface can then be exposed to a self assembling material, such as a block copolymer, such that the surface can direct assembly of the self assembling material by preferential attachment of certain moieties of the block copolymer to imaged or non-imaged portions of the surface in order to form a selected pattern.
FILED Wednesday, February 17, 2010
APPL NO 12/707129
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating processes
427/264
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US 08551714 Jovanovich et al.
FUNDED BY
Department of Homeland Security (DHS)
Homeland Security Advanced Research Projects Agency (HSARPA)
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Stevan Bogdan Jovanovich (Livermore, California);  Iuliu Ioan Blaga (Fremont, California)
ASSIGNEE(S) IntegenX Inc. (Pleasanton, California)
INVENTOR(S) Stevan Bogdan Jovanovich (Livermore, California);  Iuliu Ioan Blaga (Fremont, California)
ABSTRACT Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.
FILED Monday, February 06, 2012
APPL NO 13/367326
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08551868 Holme et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Timothy P. Holme (Menlo Park, California);  Andrei Iancu (Stanford, California);  Hee Joon Jung (Palo Alto, California);  Michael C Langston (Los Altos Hills, California);  Munekazu Motoyama (Kumamoto, Japan);  Friedrich B. Prinz (Woodside, California);  Takane Usui (Palo Alto, California);  Hitoshi Iwadate (Palo Alto, California);  Neil Dasgupta (San Francisco, California);  Cheng-Chieh Chao (Mountain View, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior Universit (Palo Alto, California);  Honda Patents and Technologies North America, LLC (Raymond, Ohio)
INVENTOR(S) Timothy P. Holme (Menlo Park, California);  Andrei Iancu (Stanford, California);  Hee Joon Jung (Palo Alto, California);  Michael C Langston (Los Altos Hills, California);  Munekazu Motoyama (Kumamoto, Japan);  Friedrich B. Prinz (Woodside, California);  Takane Usui (Palo Alto, California);  Hitoshi Iwadate (Palo Alto, California);  Neil Dasgupta (San Francisco, California);  Cheng-Chieh Chao (Mountain View, California)
ABSTRACT A method of fabricating quantum confinements is provided. The method includes depositing, using a deposition apparatus, a material layer on a substrate, where the depositing includes irradiating the layer, before a cycle, during a cycle, and/or after a cycle of the deposition to alter nucleation of quantum confinements in the material layer to control a size and/or a shape of the quantum confinements. The quantum confinements can include quantum wells, nanowires, or quantum dots. The irradiation can be in-situ or ex-situ with respect to the deposition apparatus. The irradiation can include irradiation by photons, electrons, or ions. The deposition is can include atomic layer deposition, chemical vapor deposition, MOCVD, molecular beam epitaxy, evaporation, sputtering, or pulsed-laser deposition.
FILED Thursday, March 24, 2011
APPL NO 13/065582
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/478
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552044 Owens
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Jeffery R. Owens (Panama City, Florida)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Jeffery R. Owens (Panama City, Florida)
ABSTRACT The present invention relates to coatings for disease control. More particularly, the present invention relates to coatings that are effective against toxins, precursors to these coatings and methods of forming the coatings.
FILED Wednesday, August 19, 2009
APPL NO 12/543576
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/393
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552131 Gleason et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Karen K. Gleason (Cambridge, Massachusetts);  Jingjing Xu (Cambridge, Massachusetts)
ABSTRACT Disclosed is a substantially alternating copolymer that is conformal, hard, flexible, and has low oxygen permeability. Also disclosed is an iCVD-based method of coating a substrate with the substantially alternating copolymer.
FILED Tuesday, February 12, 2013
APPL NO 13/764940
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
526/271
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552282 Garcia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Felipe A. Garcia (Panama City, Florida);  Gregory A. Reitmeyer (Panama City, Florida);  Robert C. Woodall (Panama City, Florida)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Felipe A. Garcia (Panama City, Florida);  Gregory A. Reitmeyer (Panama City, Florida);  Robert C. Woodall (Panama City, Florida)
ABSTRACT A system for reducing the operational efficiency of a watercraft's propulsion system includes a self-propelled and variable-speed unmanned underwater vehicle (UUV) that has at least one homing device adapted to direct the UUV towards an origin of a targeted watercraft's propulsion wake. At least one rod is coupled to a forward end of the UUV and extends forward therefrom at least when the UUV is in proximity to the origin of the targeted watercraft's propulsion wake. At this point, the UUV is directed and accelerated to drive the rod into the targeted watercraft's propulsor.
FILED Monday, April 11, 2011
APPL NO 13/066231
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships
114/23
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552410 Capasso et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Federico Capasso (Cambridge, Massachusetts);  Nanfang Yu (Cambridge, Massachusetts);  Romain Blanchard (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Federico Capasso (Cambridge, Massachusetts);  Nanfang Yu (Cambridge, Massachusetts);  Romain Blanchard (Cambridge, Massachusetts)
ABSTRACT A radiation-emitting device (e.g., a laser) includes an active region configured to generate a radiation emission linearly polarized along a first polarization direction and a device facet covered by an insulating layer and a metal layer on the insulating layer. The metal layer defines an aperture through which the radiation emission from the active region can be transmitted and coupled into surface plasmons on the outer side of the metal layer. The long axis of the aperture is non-orthogonal to the first polarization direction, and a sequential series of features are defined in or on the device facet or in the metal layer and spaced apart from the aperture, wherein the series of features are configured to manipulate the surface plasmons and to scatter surface plasmons into the far field with a second polarization direction distinct from the first polarization direction.
FILED Thursday, September 01, 2011
APPL NO 13/223409
ART UNIT 2881 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552435 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Qingchun Zhang (Cary, North Carolina);  Anant Agarwal (Chapel Hill, North Carolina)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Qingchun Zhang (Cary, North Carolina);  Anant Agarwal (Chapel Hill, North Carolina)
ABSTRACT Electronic device structures that compensate for non-uniform etching on a semiconductor wafer and methods of fabricating the same are disclosed. In one embodiment, the electronic device includes a number of layers including a semiconductor base layer of a first doping type formed of a desired semiconductor material, a semiconductor buffer layer on the base layer that is also formed of the desired semiconductor material, and one or more contact layers of a second doping type on the buffer layer. The one or more contact layers are etched to form a second contact region of the electronic device. The buffer layer reduces damage to the semiconductor base layer during fabrication of the electronic device. Preferably, a thickness of the semiconductor buffer layer is selected to compensate for over-etching due to non-uniform etching on a semiconductor wafer on which the electronic device is fabricated.
FILED Wednesday, July 21, 2010
APPL NO 12/840583
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/77
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552621 Piazza et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Gianluca Piazza (Philadelphia, Pennsylvania);  Nipun Sinha (Philadelphia, Pennsylvania);  Timothy S. Jones (Fort Worth, Texas);  Zhijun Guo (Philadelphia, Pennsylvania);  Graham E. Wabiszewski (Philadelphia, Pennsylvania);  Robert Carpick (Philadelphia, Pennsylvania);  Andre Dehon (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees Of The University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Gianluca Piazza (Philadelphia, Pennsylvania);  Nipun Sinha (Philadelphia, Pennsylvania);  Timothy S. Jones (Fort Worth, Texas);  Zhijun Guo (Philadelphia, Pennsylvania);  Graham E. Wabiszewski (Philadelphia, Pennsylvania);  Robert Carpick (Philadelphia, Pennsylvania);  Andre Dehon (Philadelphia, Pennsylvania)
ABSTRACT Systems and methods for operating piezoelectric switches are disclosed. A piezoelectric switching system includes a first actuator, a second actuator, and a bias voltage source. The first actuator has a first body electrode, a first gate electrode, and a first contact region. The second actuator has a second body electrode, a second gate electrode, and a second contact region. The first and second contact regions are separated by a gap. The bias voltage source applies a bias voltage to the body electrodes. The bias voltage is lower in magnitude than an actuation voltage for the switch. The gate electrodes receive a switching voltage. The switching voltage causes at least one of the first and second actuators to bend, thereby closing the gap such that the second contact region electrically contacts the first contact region. The difference between the switching voltage and the bias voltage exceeds the actuation voltage of the switch.
FILED Monday, November 29, 2010
APPL NO 12/955285
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electric Switches; Relays; Selectors; Emergency Protective Devices
H01H 57/00 (20130101)
H01H 2057/006 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/094 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552708 de Rochemont
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
United States Marine Corps (USMC)
U.S. Marine Corps
Marine Corps Systems Command (MARCORSYSCOM)
APPLICANT(S) L. Pierre de Rochemont (Austin, Texas)
ASSIGNEE(S)
INVENTOR(S) L. Pierre de Rochemont (Austin, Texas)
ABSTRACT A monolithic DC to DC converter, provides a semiconductor substrate, a surface FET formed on the semiconductor substrate that modulates currents across a surface of the semiconductor substrate, and a toroidal inductor with a magnetic core formed on the substrate around the FET and having a first winding connected to the FET.
FILED Thursday, June 02, 2011
APPL NO 13/152222
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Electricity: Power supply or regulation systems
323/355
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08553237 Kominsky
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Daniel Kominsky (Christiansburg, Virginia)
ASSIGNEE(S) Prime Photonics, LC (Blacksburg, Virginia)
INVENTOR(S) Daniel Kominsky (Christiansburg, Virginia)
ABSTRACT The sensor comprises a beam of electromagnetic radiation projecting across a gap between the stationary member and the translating member, a reference detector having a reference FOV and a signal detector having a signal FOV. The sensor is to be mounted on the stationary member. The electromagnetic radiation beam, the reference FOV and the signal FOV intersect in a volume including the gap, and the gap is calculated from the reflected electromagnetic radiation received by the reference and signal detectors. The gap can be determined from a ratio between a rise time in the signal pulse and a rise time in the reference pulse, or a ratio between a fall time in the signal pulse and a fall time in the reference pulse, or a ratio between a delay time in the signal pulse and a delay time in the reference pulse, among other features.
FILED Tuesday, January 10, 2012
APPL NO 13/347299
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/625
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US 08553690 Arroyo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Jesse P. Arroyo (Rochester, Minnesota);  Timothy R. Block (Rochester, Minnesota);  Leonardo Letourneaut (Rochester, Minnesota);  Timothy J. Schimke (Stewartville, Minnesota)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Jesse P. Arroyo (Rochester, Minnesota);  Timothy R. Block (Rochester, Minnesota);  Leonardo Letourneaut (Rochester, Minnesota);  Timothy J. Schimke (Stewartville, Minnesota)
ABSTRACT Processing multicast messages in a data processing system that includes compute nodes, each of which includes a communications controller, the communications controllers operatively coupled for data communications amongst the compute nodes, each compute node in the data processing system executing at least one logical partition, the data processing system including a hypervisor, where multicast messages are processed by receiving, by more than one of the communications controllers, a multicast message; responsive to receipt of the multicast message, signaling, by one of the communications controllers, an interrupt in the hypervisor without signaling an interrupt by any other communications controller; determining, by the hypervisor, that the message received by the interrupt signaling communications controller is a multicast message; and providing, by the hypervisor, the multicast message to at least one logical partition configured to receive multicast messages.
FILED Wednesday, December 15, 2010
APPL NO 12/968580
ART UNIT 2469 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/390
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US 08553817 Dinh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Vincent V. Dinh (San Diego, California);  Daniel W. Tam (San Diego, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Vincent V. Dinh (San Diego, California);  Daniel W. Tam (San Diego, California)
ABSTRACT Systems and methods are disclosed for removing interference in a time-harmonic received composite signal, comprising, sampling an in-band interfering signal from a stationary transmitter at a stationary receiver; sampling a composite signal having the in-band interfering signal and an in-band desired signal from a stationary transmitter at the receiver, deriving at least one of a phase and time difference from the composite signal and sampled in-band interfering signal, applying the derived at least one of phase and time difference to the sampled in-band interfering signal to estimate a synchronized current in-band interfering signal, and generating the un-interfered, in-band desired signal by subtracting the synchronized current in-band interfering signal from a current composite signal.
FILED Tuesday, March 01, 2011
APPL NO 13/038177
ART UNIT 2631 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/346
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US 08553937 Jelinek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Research, Development and Engineering Command (RDECOM)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Jan Jelinek (Plymouth, Minnesota);  Sharath Venkatesha (Golden Valley, Minnesota);  Vincent Jacobson (Eden Prairie, Minnesota)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Jan Jelinek (Plymouth, Minnesota);  Sharath Venkatesha (Golden Valley, Minnesota);  Vincent Jacobson (Eden Prairie, Minnesota)
ABSTRACT An apparatus includes a video sensing device, a velocity vector estimator (VVE) coupled to the video sensing device, a controller coupled to the velocity vector estimator, and an orthogonal transfer charge-coupled device (OTCCD) coupled to the controller. The video sensing device transmits a plurality of image frames to the velocity vector estimator. The controller receives a location of an object in a current frame, stores locations of the object in one or more previous frames, predicts a motion trajectory and the predicted location of the object on it in a subsequent frame as a function of the locations of the object in the current frame and the one or more previous frames, and transmits the predicted location of the object to the OTCCD. The OTCCD shifts its image array of pixels as a function of the predicted location of the object.
FILED Thursday, October 20, 2011
APPL NO 13/277621
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/103
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US 08553989 Owechko et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Yuri Owechko (Newbury Park, California);  Swarup Medasani (Thousand Oaks, California);  Jim Nelson (Sumner, Washington)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Yuri Owechko (Newbury Park, California);  Swarup Medasani (Thousand Oaks, California);  Jim Nelson (Sumner, Washington)
ABSTRACT The present invention relates to a method for three-dimensional (3D) object recognition using region of interest geometric features. The method includes acts of receiving an implicit geometry representation regarding a three-dimensional (3D) object of interest. A region of interest (ROI) is centered on the implicit geometry representation such that there is at least one intersection area between the ROI and the implicit geometry representation. Object shape features are calculated that reflect a location of the ROI with respect to the implicit geometry representation. The object shape features are assembled into a feature vector. A classification confidence value is generated with respect to a particular object classification. Finally, the 3D object of interest is classified as a particular object upon the output of a statistical classifier reaching a predetermined threshold.
FILED Tuesday, April 27, 2010
APPL NO 12/799618
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/224
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US 08554031 Astratov
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Vasily N. Astratov (Charlotte, North Carolina)
ASSIGNEE(S) University of North Carolina at Charlotte (Charlotte, North Carolina)
INVENTOR(S) Vasily N. Astratov (Charlotte, North Carolina)
ABSTRACT The present invention provides an optical microprobe device and method for focusing multimodal radiation with wavelength-scale spatial resolution and delivering the focused radiation to a specimen, including: a radiation source; and one or more of a plurality of optically transparent or semitransparent spheres and a plurality of optically transparent or semitransparent cylinders optically coupled to the radiation source; wherein the one or more of the plurality of optically transparent or semitransparent spheres and the plurality of optically transparent or semitransparent cylinders periodically focus radiation optically transmitted from the radiation source such that radiation ultimately transmitted to the specimen has predetermined characteristics. Preferably, the spheres or cylinders are assembled inside one of a hollow waveguide, a hollow-core photonic crystal fiber, a capillary tube, and integrated in a multimode fiber. Alternatively, the spheres or cylinders are assembled on a substrate. Optionally, the optical microprobe device also includes one or more of a waveguide, an optical fiber, a lens, and an optical structure disposed between the radiation source and the spheres or cylinders. Optionally, the spheres or cylinders are made from optically nonlinear or active materials that permit efficient nonlinear frequency generation and low-threshold lasing using the optical microprobe device.
FILED Tuesday, June 08, 2010
APPL NO 13/321965
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/35
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US 08554085 Yap et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Daniel Yap (Newbury Park, California);  Keyvan Sayyah (Santa Monica, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Daniel Yap (Newbury Park, California);  Keyvan Sayyah (Santa Monica, California)
ABSTRACT A spread spectrum waveform generator has a photonic oscillator and an optical heterodyne synthesizer. The photonic oscillator is a multi-tone optical comb generator for generating a series of RF comb lines on an optical carrier. The optical heterodyne synthesizer includes first and second phase-locked lasers, where the first laser feeds the multi-tone optical comb generator and the second laser is a single tone laser whose output light provides a frequency translation reference. At least one photodetector is provided for heterodyning the frequency translation reference with the optical output of the photonic oscillator to generate a spread spectrum waveform. A receiver pre-processor may be provided to operate on the spread spectrum waveform.
FILED Tuesday, December 01, 2009
APPL NO 12/628783
ART UNIT 2634 — Digital Communications
CURRENT CPC
Transmission
H04B 10/505 (20130101) Original (OR) Class
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US 08554488 Wigler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Michael H. Wigler (Cold Spring Harbor, New York);  Lakshmi Muthuswamy (Toronto, Canada);  Jonathan Sebat (San Diego, California)
ASSIGNEE(S) Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
INVENTOR(S) Michael H. Wigler (Cold Spring Harbor, New York);  Lakshmi Muthuswamy (Toronto, Canada);  Jonathan Sebat (San Diego, California)
ABSTRACT The present invention provides methods and compositions related to genomic profiling, and in particular, to assigning probabilistic measure of clinical outcome for a patient having a disease or a tumor using segmented genomic profiles such as those produced by representational oligonucleotide microarray analysis (ROMA).
FILED Thursday, December 14, 2006
APPL NO 11/639712
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 1/6886 (20130101)

Electric Digital Data Processing
G06F 19/18 (20130101)
G06F 19/34 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08554533 Cutts et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Andrew Cutts (Henniker, New Hampshire);  Robert Schmidt (Chicago, Illinois)
ASSIGNEE(S) Norwich University Applied Research Institutes (Northfield, Vermont)
INVENTOR(S) Andrew Cutts (Henniker, New Hampshire);  Robert Schmidt (Chicago, Illinois)
ABSTRACT Methods and apparatus for advancing time in a distributed business process simulation are disclosed. The methods and apparatus simulate an interdependent business process, such as a financial transaction system, in a secure distributed manner. Each business entity that is part of the interdependent business process models itself on a local client device at any chosen level of detail. A simulation server connects the separate client based simulations into one large simulation. Details of each local simulation may be hidden from other simulation participants. However, interruptions in business flow caused by simulated disruptions introduced at the simulation server and/or a client device are propagated to all of the effected simulation participants via the simulation server. In addition, simulation time may be warped from one breakpoint to another breakpoint thereby facilitating an efficient ratio of simulation time to real time.
FILED Friday, November 18, 2011
APPL NO 13/299521
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/22
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US 08554796 Narain et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Sanjai Narain (Madison, New Jersey);  Gary Levin (Bedminster, New Jersey)
ASSIGNEE(S) TT Government Solutions, Inc. (Basking Ridge, New Jersey)
INVENTOR(S) Sanjai Narain (Madison, New Jersey);  Gary Levin (Bedminster, New Jersey)
ABSTRACT A method is provided for analyzing the semantic content of network configuration files, comprising the steps of accessing configuration files associated with corresponding network components, the files containing commands that define the configuration of those components; transforming the commands into a structural database based, at least in part, on a non-grammatical analysis of the commands, wherein the structure of the commands is represented as the structural database; and constructing a semantic database of the configuration files by querying the structural database.
FILED Friday, July 16, 2010
APPL NO 12/837642
ART UNIT 2167 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/791
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US 08554816 Olson
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S) John V. Olson (Fairbanks, Alaska)
ASSIGNEE(S) University of Alaska Fairbanks (Fairbanks, Alaska)
INVENTOR(S) John V. Olson (Fairbanks, Alaska)
ABSTRACT Embodiments described herein describe the construction of frequency domain estimates of generalized power density and the filters that can be constructed from those estimates. Using the concept of the Stokes vector representation of the spectral matrix in an M-dimensional vector space, a generalization of the process in which the spectral matrix may be represented by a set of trace-orthogonal matrices that are based upon a particular signal state can be produced. One aspect of the process is as follows: given a particular signal, represented as by a state vector in the space, a complete, orthonormal set of vectors can be produced that includes the signal of interest. Then, a generalized set of matrices is constructed, based upon the developed vectors, that are trace-orthogonal and which serve as a basis set for the expansion of the spectral matrix. The coefficients of this expansion form a generalized Stokes vector that represents the power in the spectral matrix associated with the various state vectors. Filters that serve to extract or suppress information about a particular state may then be constructed using the components of the generalized Stokes vectors. The effectiveness of an embodiment this filter is demonstrated using acoustic data from a microphone array.
FILED Thursday, August 26, 2010
APPL NO 12/869342
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers: Arithmetic processing and calculating
78/308
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US 08555013 Vick et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Christopher A. Vick (San Jose, California);  Michael H. Paleczny (San Jose, California);  Jay R. Freeman (Palo Alto, California);  Olaf Manczak (Hayward, California);  Phyllis E. Gustafson (Pleasanton, California);  Yuguang Wu (Santa Clara, California)
ASSIGNEE(S) Oracle America, Inc. (Redwood City, California)
INVENTOR(S) Christopher A. Vick (San Jose, California);  Michael H. Paleczny (San Jose, California);  Jay R. Freeman (Palo Alto, California);  Olaf Manczak (Hayward, California);  Phyllis E. Gustafson (Pleasanton, California);  Yuguang Wu (Santa Clara, California)
ABSTRACT A method for memory protection in a multiprocessor system, involving receiving a request at a first carrier to perform a memory operation at a memory address, wherein the first carrier receives the request from a processor, determining by the first carrier whether the processor is permitted to access memory at the memory address using a carrier identification (ID) of a second carrier, wherein the second carrier is associated with a memory controller used to access the memory, and sending the request to the second carrier, if the processor is permitted to access the memory.
FILED Wednesday, June 22, 2005
APPL NO 11/158774
ART UNIT 2189 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/163
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US 08555119 Chang et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Leland Chang (New York, New York);  Jente B. Kuang (Austin, Texas);  Robert K. Montoye (New York, New York);  Hung C. Ngo (Austin, Texas);  Kevin J. Nowka (Georgetown, Texas)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Leland Chang (New York, New York);  Jente B. Kuang (Austin, Texas);  Robert K. Montoye (New York, New York);  Hung C. Ngo (Austin, Texas);  Kevin J. Nowka (Georgetown, Texas)
ABSTRACT A test structure for characterizing a production static random access memory (SRAM) array. The test structure includes a characterization circuit having multiple memory cell columns connected in series to form a ring configuration. The characterization circuit is fabricated on a wafer substrate in common with and proximate to a production SRAM array. The characterization circuit preferably includes SRAM cells having a circuit topology substantially identical to the circuit topology of memory cells within the production SRAM array. In one embodiment, the test structure is utilized for characterizing a multi-port memory array and includes multiple memory cell columns connected in series to form a ring oscillator characterization circuit. Each cell column in the characterization circuit includes multiple SRAM cells each having a latching node and multiple data path access nodes. Selection control circuitry selectively enables the multiple data path access nodes for the SRAM cells within the characterization circuit.
FILED Monday, April 30, 2012
APPL NO 13/459932
ART UNIT 2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/718
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US 08555240 Bouillet et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New York);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New York);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ABSTRACT A method, including: providing a computer menu from which a processing goal can be created, wherein the menu includes a plurality of facets, and wherein each facet includes at least one tag; receiving a processing goal, wherein the processing goal includes a plurality of tags selected from the menu; executing at least one application that includes a plurality of components arranged in a processing graph to produce information that satisfies the processing goal; and outputting the information.
FILED Wednesday, October 15, 2008
APPL NO 12/252132
ART UNIT 2198 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Data processing: Software development, installation, and management
717/101
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US 08555354 Iasso
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
APPLICANT(S) Anthony S. Iasso (Haymarket, Virginia)
ASSIGNEE(S) Anthony S. Iasso (Haymarkey, Virginia)
INVENTOR(S) Anthony S. Iasso (Haymarket, Virginia)
ABSTRACT A watchlisting module is configured to securely and efficiently create, modify, manage, and store a watchlist. The watchlisting module is configured to generate a watchlist consisting of watchlist entries. Each watchlist entry encapsulates information about an entity to be associated with the watchlist. The watchlist entry includes information about the entity including a unique identifier for the watchlist, a unique identifier of the watchlist entry, a unique identifier for the entity, and access control information for membership process related to the watchlist. The watchlist entry also includes a State Lock. Watchlisting module is configured to utilize the State Lock to secure and verify a watchlist entry.
FILED Thursday, February 21, 2008
APPL NO 12/918581
ART UNIT 2438 — Cryptography and Security
CURRENT CPC
Information security
726/5
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Department of Energy (DOE) 

US 08549846 Gonze et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Eugene V. Gonze (Pinckney, Michigan);  Frank Ament (Troy, Michigan)
ASSIGNEE(S) GM Global Technology Operations LLC (, None)
INVENTOR(S) Eugene V. Gonze (Pinckney, Michigan);  Frank Ament (Troy, Michigan)
ABSTRACT An exhaust system that processes exhaust generated by an engine is provided. The system includes: a particulate filter (PF) that filters particulates from the exhaust wherein an upstream end of the PF receives exhaust from the engine; and a grid of electrically resistive material that is applied to an exterior upstream surface of the PF and that selectively heats exhaust passing through the grid to initiate combustion of particulates within the PF.
FILED Wednesday, November 08, 2006
APPL NO 11/557715
ART UNIT 3748 — SELECT * FROM codes_techcenter;
CURRENT CPC
Power plants
060/297
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US 08550283 Morgan et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) James W. Morgan (LaGrange, Illinois);  Donald E. Preuss (Hinsdale, Illinois);  Daniel M. Nestor (New Lenox, Illinois)
ASSIGNEE(S) Uchicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) James W. Morgan (LaGrange, Illinois);  Donald E. Preuss (Hinsdale, Illinois);  Daniel M. Nestor (New Lenox, Illinois)
ABSTRACT A lid system for a shielding cask is provided, the system comprising a plurality of contiguous panels, each panel is axially actuated by a first lift piston located laterally from the casks' longitudinal principal axis, and rotated about the cask by a ‘hinge’ piston at approximately 90 degrees along an arc from the first piston, the arc formed by a portion of the lip of the cask.
FILED Monday, August 08, 2011
APPL NO 13/205520
ART UNIT 3788 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Receptacles
220/260
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US 08550467 Dietle et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Lannie Laroy Dietle (Houston, Texas);  John Erick Schroeder (Houston, Texas)
ASSIGNEE(S) Kalsi Engineering, Inc. (Sugar Land, Texas)
INVENTOR(S) Lannie Laroy Dietle (Houston, Texas);  John Erick Schroeder (Houston, Texas)
ABSTRACT The present invention is a generally circular rotary seal that establishes sealing between relatively rotatable machine components for lubricant retention and environmental exclusion, and incorporates seal geometry that interacts with the lubricant during relative rotation to distribute a lubricant film within the dynamic sealing interface. The features of a variable inlet size, a variable dynamic lip flank slope, and a reduction in the magnitude and circumferentially oriented portion of the lubricant side interfacial contact pressure zone at the narrowest part of the lip, individually or in combination thereof, serve to maximize interfacial lubrication in severe operating conditions, and also serve to minimize lubricant shear area, seal torque, seal volume, and wear, while ensuring retrofitability into the seal grooves of existing equipment.
FILED Tuesday, September 02, 2008
APPL NO 12/231348
ART UNIT 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Seal for a joint or juncture
277/559
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08550792 Solovyeva et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Lyudmila Mikhaylovna Solovyeva (Ann Arbor, Michigan);  Kyle S. Jansson (St. Louis Park, Minnesota);  Alaa AbdelAzim Elmoursi (Troy, Michigan);  Dong Zhu (Farmington Hills, Michigan);  Robert Milner (Warren, Michigan);  Earl Eugene Daugherty (Greenwood, South Carolina);  Clifton Baxter Higdon (Birmingham, Michigan);  Kamel Abdel-Khalik Elagamy (Livonia, Michigan);  Aaron Michael Hicks (Eden Prairie, Minnesota)
ASSIGNEE(S) Eaton Corporation (Cleveland, Ohio)
INVENTOR(S) Lyudmila Mikhaylovna Solovyeva (Ann Arbor, Michigan);  Kyle S. Jansson (St. Louis Park, Minnesota);  Alaa AbdelAzim Elmoursi (Troy, Michigan);  Dong Zhu (Farmington Hills, Michigan);  Robert Milner (Warren, Michigan);  Earl Eugene Daugherty (Greenwood, South Carolina);  Clifton Baxter Higdon (Birmingham, Michigan);  Kamel Abdel-Khalik Elagamy (Livonia, Michigan);  Aaron Michael Hicks (Eden Prairie, Minnesota)
ABSTRACT A device configured for converting energy includes a first surface, a second surface configured for moving with respect to the first surface during operation of the device, and a coating disposed on at least one of the first surface and the second surface. The coating includes a first layer of a ceramic alloy represented by the general formula AlMgB14—X, wherein X is present in an amount of from 0 to 70 parts by weight based on 100 parts by weight of the ceramic alloy and is a doping agent selected from the group of Group IV elements and borides and nitrides thereof, and a second layer disposed on the first layer and including carbon in a gradient concentration. The coating has a hardness of from 10 to 20 GPa and a coefficient of friction of less than or equal to 0.12.
FILED Monday, June 29, 2009
APPL NO 12/493885
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Pumps
417/310
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US 08551361 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Yuanqiang Li (Plainsboro, New Jersey);  Michael Dennis Romanelli (North Plainfield, New Jersey);  Yongchi Tian (Princeton Junction, New Jersey)
ASSIGNEE(S) Lightscape Materials, Inc. (Princeton, New Jersey)
INVENTOR(S) Yuanqiang Li (Plainsboro, New Jersey);  Michael Dennis Romanelli (North Plainfield, New Jersey);  Yongchi Tian (Princeton Junction, New Jersey)
ABSTRACT Disclosed herein is a novel family of oxycarbidonitride phosphor compositions and light emitting devices incorporating the same. Within the sextant system of M—Al—Si—O—N—C—Ln and quintuplet system of M—Si—O—N—C—Ln (M=alkaline earth element, Ln=rare earth element), the phosphors are composed of either one single crystalline phase or two crystalline phases with high chemical and thermal stability. In certain embodiments, the disclosed phosphor of silicon oxycarbidonitrides emits green light at wavelength between 530-550 nm. In further embodiments, the disclosed phosphor compositions emit blue-green to yellow light in a wavelength range of 450-650 nm under near-UV and blue light excitation.
FILED Friday, March 11, 2011
APPL NO 13/046388
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compositions
252/301.4F0
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US 08551448 VanBrocklin et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Henry F. VanBrocklin (Walnut Creek, California);  James P. O'Neil (San Leandro, California);  Andrew R. Gibbs (Pleasant Hill, California);  Nandanan Erathodiyil (Singapore, Singapore)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Henry F. VanBrocklin (Walnut Creek, California);  James P. O'Neil (San Leandro, California);  Andrew R. Gibbs (Pleasant Hill, California);  Nandanan Erathodiyil (Singapore, Singapore)
ABSTRACT The present invention provides rotenone analogs and methods of making and using them. Labeled with single photon and positron emitting isotopes, the rotenone analogs of the present invention are useful in, for example, clinical imaging applications as tracers to measure cardiac blood flow and detect regions of ischemia.
FILED Tuesday, November 18, 2008
APPL NO 12/273509
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.810
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US 08551453 Raymond et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Kenneth N. Raymond (Berkeley, California);  Stephane Petoud (Pittsburgh, Pennsylvania);  Jide Xu (Berkeley, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Kenneth N. Raymond (Berkeley, California);  Stephane Petoud (Pittsburgh, Pennsylvania);  Jide Xu (Berkeley, California)
ABSTRACT The present invention provides luminescent lanthanide metal chelates comprising a metal ion of the lanthanide series and a complexing agent comprising at least one phthalamidyl moiety. Also provided are probes incorporating the phthalamidyl ligands of the invention and methods utilizing the ligands of the invention and probes comprising the ligands of the invention.
FILED Wednesday, December 29, 2004
APPL NO 10/585178
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.600
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US 08551607 Chu et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Henry S. Chu (Idaho Falls, Idaho);  Thomas M. Lillo (Idaho Falls, Idaho);  Kevin M. McHugh (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Henry S. Chu (Idaho Falls, Idaho);  Thomas M. Lillo (Idaho Falls, Idaho);  Kevin M. McHugh (Idaho Falls, Idaho)
ABSTRACT An armor system and method involves providing a core material and a stream of atomized coating material that comprises a liquid fraction and a solid fraction. An initial layer is deposited on the core material by positioning the core material in the stream of atomized coating material wherein the solid fraction of the stream of atomized coating material is less than the liquid fraction of the stream of atomized coating material on a weight basis. An outer layer is then deposited on the initial layer by positioning the core material in the stream of atomized coating material wherein the solid fraction of the stream of atomized coating material is greater than the liquid fraction of the stream of atomized coating material on a weight basis.
FILED Wednesday, September 29, 2010
APPL NO 12/893192
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/212
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US 08551617 Taboada-Serrano et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Patricia Taboada-Serrano (La Paz, Bolivia);  Constantino Tsouris (Oak Ridge, Tennessee);  Cristian I. Contescu (Knoxville, Tennessee);  Joanna McFarlane (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Patricia Taboada-Serrano (La Paz, Bolivia);  Constantino Tsouris (Oak Ridge, Tennessee);  Cristian I. Contescu (Knoxville, Tennessee);  Joanna McFarlane (Oak Ridge, Tennessee)
ABSTRACT The present invention provides magnetically responsive activated carbon, and a method of forming magnetically responsive activated carbon. The method of forming magnetically responsive activated carbon typically includes providing activated carbon in a solution containing ions of ferrite forming elements, wherein at least one of the ferrite forming elements has an oxidation state of +3 and at least a second of the ferrite forming elements has an oxidation state of +2, and increasing pH of the solution to precipitate particles of ferrite that bond to the activated carbon, wherein the activated carbon having the ferrite particles bonded thereto have a positive magnetic susceptibility. The present invention also provides a method of filtering waste water using magnetic activated carbon.
FILED Thursday, December 18, 2008
APPL NO 12/338442
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/403
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US 08551650 Kung et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Harold H. Kung (Wilmette, Illinois);  Xin Zhao (Evanston, Illinois);  Cary M. Hayner (Evanston, Illinois);  Mayfair C. Kung (Wilmette, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Harold H. Kung (Wilmette, Illinois);  Xin Zhao (Evanston, Illinois);  Cary M. Hayner (Evanston, Illinois);  Mayfair C. Kung (Wilmette, Illinois)
ABSTRACT Graphene-based storage materials for high-power battery applications are provided. The storage materials are composed of vertical stacks of graphene sheets and have reduced resistance for Li ion transport. This reduced resistance is achieved by incorporating a random distribution of structural defects into the stacked graphene sheets, whereby the structural defects facilitate the diffusion of Li ions into the interior of the storage materials.
FILED Thursday, May 12, 2011
APPL NO 13/106210
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/188
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US 08551661 Amine et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Khalil Amine (Oakbrook, Illinois);  Jaekook Kim (Naperville, Illinois);  Donald R. Vissers (Naperville, Illinois)
ASSIGNEE(S) Uchicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Khalil Amine (Oakbrook, Illinois);  Jaekook Kim (Naperville, Illinois);  Donald R. Vissers (Naperville, Illinois)
ABSTRACT The present invention relates to non-aqueous electrolytes having stabilization additives and electrochemical devices containing the same. Thus the present invention provides electrolytes containing an alkali metal salt, a polar aprotic solvent, a first additive that is a substituted or unsubstituted organoamine, substituted or unsubstituted alkane, substituted or unsubstituted alkene, or substituted or unsubstituted aryl compound, and/or a second additive that is a metal (chelato)borate. When used in electrochemical devices with, e.g., lithium manganese oxide spinel electrodes, the new electrolytes provide batteries with improved calendar and cycle life.
FILED Thursday, May 26, 2011
APPL NO 13/116559
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/322
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US 08551917 Unkefer et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S) Pat J. Unkefer (Los Alamos, New Mexico);  Rodolfo A. Martinez (Santa Fe, New Mexico);  Thomas J. Knight (Raymond, Maine)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Pat J. Unkefer (Los Alamos, New Mexico);  Rodolfo A. Martinez (Santa Fe, New Mexico);  Thomas J. Knight (Raymond, Maine)
ABSTRACT The present invention describes a composition including a mixture of L- and D-pyroglutamate stereoisomers in a ratio of L to D of from about 80:20 to about 97:3, and, a carrier medium for application of the L- and D-pyroglutamate stereoisomers to a target plant. The composition can also be used as a germination medium and may be incorporated into a seed coat for assisting in germination. The present invention further describes a method of increasing the agronomic performance of a target plant by treating a target plant with a composition including a mixture of L- and D-pyroglutamate stereoisomers in a ratio of L to D of from about 80:20 to about 97:3 and a carrier medium for said L- and D-pyroglutamate stereoisomers.
FILED Monday, November 07, 2005
APPL NO 11/269417
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Plant protecting and regulating compositions
54/138
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US 08552100 Song et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Jie Song (Shrewsbury, Massachusetts);  Eduardo Saiz (Berkeley, California);  Carolyn R. Bertozzi (Berkeley, California);  Antoni P. Tomsia (Pinole, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jie Song (Shrewsbury, Massachusetts);  Eduardo Saiz (Berkeley, California);  Carolyn R. Bertozzi (Berkeley, California);  Antoni P. Tomsia (Pinole, California)
ABSTRACT A composite having a flexible hydrogel polymer formed by mixing an organic phase with an inorganic composition, the organic phase selected from the group consisting of a hydrogel monomer, a crosslinker, a radical initiator, and/or a solvent. A polymerization mixture is formed and polymerized into a desired shape and size.
FILED Wednesday, February 22, 2006
APPL NO 11/817016
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
524/417
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US 08552144 Javier et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Anna Esmeralda K. Javier (Berkeley, California);  Nitash Pervez Balsara (El Cerrito, California);  Shrayesh Naran Patel (Berkeley, California);  Daniel T. Hallinan, Jr. (Walnut Creek, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Anna Esmeralda K. Javier (Berkeley, California);  Nitash Pervez Balsara (El Cerrito, California);  Shrayesh Naran Patel (Berkeley, California);  Daniel T. Hallinan, Jr. (Walnut Creek, California)
ABSTRACT Redox reactions that occur at the electrodes of batteries require transport of both ions and electrons to the active centers. Reported is the synthesis of a block copolymer that exhibits simultaneous electronic and ionic conduction. A combination of Grignard metathesis polymerization and click reaction was used successively to synthesize the block copolymer containing regioregular poly(3-hexylthiophene) (P3HT) and poly(ethylene oxide) (PEO) segments. The P3HT-PEO/LiTFSI mixture was then used to make a lithium battery cathode with LiFePO4 as the only other component. All-solid lithium batteries of the cathode described above, a solid electrolyte and a lithium foil as the anode showed capacities within experimental error of the theoretical capacity of the battery. The ability of P3HT-PEO to serve all of the transport and binding functions required in a lithium battery electrode is thus demonstrated.
FILED Thursday, March 22, 2012
APPL NO 13/427640
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
528/380
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US 08552169 Dietrich et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Jeffrey A. Dietrich (San Francisco, California);  Jay D. Keasling (Berkeley, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jeffrey A. Dietrich (San Francisco, California);  Jay D. Keasling (Berkeley, California)
ABSTRACT The present invention provides for a system comprising a BmoR transcription factor, a σ54-RNA polymerase, and a pBMO promoter operatively linked to a reporter gene, wherein the pBMO promoter is capable of expression of the reporter gene with an activated form of the BmoR and the σ54-RNA polymerase.
FILED Monday, April 26, 2010
APPL NO 12/767649
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.100
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US 08552288 Xavier
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Grace Xavier (Fremont, California)
ASSIGNEE(S) SunPower Corporation (San Jose, California)
INVENTOR(S) Grace Xavier (Fremont, California)
ABSTRACT Photovoltaic modules with adhesion promoters and methods for fabricating photovoltaic modules with adhesion promoters are described. A photovoltaic module includes a solar cell including a first surface and a second surface, the second surface including a plurality of interspaced back-side contacts. A first glass layer is coupled to the first surface by a first encapsulating layer. A second glass layer is coupled to the second surface by a second encapsulating layer. At least a portion of the second encapsulating layer is bonded directly to the plurality of interspaced back-side contacts by an adhesion promoter.
FILED Monday, October 12, 2009
APPL NO 12/577622
ART UNIT 1758 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/259
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US 08552299 Rogers et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Materials Sciences and Engineering Division (MSE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) John A. Rogers (Champaign, Illinois);  Yonggang Huang (Glencoe, Illinois);  Heung Cho Ko (Urbana, Illinois);  Mark Stoykovich (Dover, New Hampshire);  Won Mook Choi (Champaign, Illinois);  Jizhou Song (Miami, Florida);  Jong Hyun Ahn (Gyeonggi-do, South Korea);  Dae Hyeong Kim (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) John A. Rogers (Champaign, Illinois);  Yonggang Huang (Glencoe, Illinois);  Heung Cho Ko (Urbana, Illinois);  Mark Stoykovich (Dover, New Hampshire);  Won Mook Choi (Champaign, Illinois);  Jizhou Song (Miami, Florida);  Jong Hyun Ahn (Gyeonggi-do, South Korea);  Dae Hyeong Kim (Champaign, Illinois)
ABSTRACT Disclosed herein are stretchable, foldable and optionally printable, processes for making devices and devices such as semiconductors, electronic circuits and components thereof that are capable of providing good performance when stretched, compressed, flexed or otherwise deformed. Strain isolation layers provide good strain isolation to functional device layers. Multilayer devices are constructed to position a neutral mechanical surface coincident or proximate to a functional layer having a material that is susceptible to strain-induced failure. Neutral mechanical surfaces are positioned by one or more layers having a property that is spatially inhomogeneous, such as by patterning any of the layers of the multilayer device.
FILED Thursday, March 05, 2009
APPL NO 12/398811
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Conductors and insulators
174/254
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US 08552370 Schultz et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Larry Joe Schultz (Los Alamos, New Mexico);  Alexei Vasilievich Klimenko (Maynard, Massachusetts);  Andrew Mcleod Fraser (Los Alamos, New Mexico);  Christopher Morris (Los Alamos, New Mexico);  John Christopher Orum (Los Alamos, New Mexico);  Konstantin N. Borozdin (Los Alamos, New Mexico);  Michael James Sossong (Los Alamos, New Mexico);  Nicolas W. Hengartner (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Larry Joe Schultz (Los Alamos, New Mexico);  Alexei Vasilievich Klimenko (Maynard, Massachusetts);  Andrew Mcleod Fraser (Los Alamos, New Mexico);  Christopher Morris (Los Alamos, New Mexico);  John Christopher Orum (Los Alamos, New Mexico);  Konstantin N. Borozdin (Los Alamos, New Mexico);  Michael James Sossong (Los Alamos, New Mexico);  Nicolas W. Hengartner (Los Alamos, New Mexico)
ABSTRACT Systems and methods for charged particle detection including statistical reconstruction of object volume scattering density profiles from charged particle tomographic data to determine the probability distribution of charged particle scattering using a statistical multiple scattering model and determine a substantially maximum likelihood estimate of object volume scattering density using expectation maximization (ML/EM) algorithm to reconstruct the object volume scattering density. The presence of and/or type of object occupying the volume of interest can be identified from the reconstructed volume scattering density profile. The charged particle tomographic data can be cosmic ray muon tomographic data from a muon tracker for scanning packages, containers, vehicles or cargo. The method can be implemented using a computer program which is executable on a computer.
FILED Wednesday, October 24, 2007
APPL NO 11/977409
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/201 (20130101) Original (OR) Class
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US 08552391 Terenetska et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Iryna P. Terenetska (Kiev, Ukraine);  Tetiana M. Orlova (Kiev, Ukraine);  Eugene K. Kirilenko (Kiev, Ukraine);  Grygory A Galich (Kiev, Ukraine);  Anna M. Eremneko (Kiev, Ukraine)
ASSIGNEE(S) Lawrence Livermore National Security, LLC. (Livermore, California)
INVENTOR(S) Iryna P. Terenetska (Kiev, Ukraine);  Tetiana M. Orlova (Kiev, Ukraine);  Eugene K. Kirilenko (Kiev, Ukraine);  Grygory A Galich (Kiev, Ukraine);  Anna M. Eremneko (Kiev, Ukraine)
ABSTRACT A matrix with a biologically active substance is exposed to UV radiation. The biologically active substance is selected to initiate photoconversions originating vitamin D synthesis. An optical parameter of the biologically active substance is being changed under UV irradiation. Change of the optical parameter is measured, thus measuring the amount of UV radiation that has caused the vitamin D synthesis occurred through photoconversion. Measuring occurs by way of a dosimeter.
FILED Tuesday, March 23, 2010
APPL NO 13/148804
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/370.70
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US 08552419 Jen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Kwan-Yue Jen (Kenmore, Washington);  Fei Huang (Guangzhou, China PRC);  Hin-Lap Yip (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Kwan-Yue Jen (Kenmore, Washington);  Fei Huang (Guangzhou, China PRC);  Hin-Lap Yip (Seattle, Washington)
ABSTRACT Cross-conjugated donor-acceptor polymers, methods for their preparation, devices that include polymers, and methods for the preparation and use of the devices.
FILED Thursday, July 28, 2011
APPL NO 13/192961
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Active solid-state devices
257/40
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US 08552429 Luke et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Paul N. Luke (Castro Valley, California);  Craig S. Tindall (San Ramon, California);  Mark Amman (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Paul N. Luke (Castro Valley, California);  Craig S. Tindall (San Ramon, California);  Mark Amman (San Francisco, California)
ABSTRACT A non-contact charge sensor includes a semiconductor detector having a first surface and an opposing second surface. The detector includes a high resistivity electrode layer on the first surface and a low resistivity electrode on the high resistivity electrode layer. A portion of the low resistivity first surface electrode is deleted to expose the high resistivity electrode layer in a portion of the area. A low resistivity electrode layer is disposed on the second surface of the semiconductor detector. A voltage applied between the first surface low resistivity electrode and the second surface low resistivity electrode causes a free charge to drift toward the first or second surface according to a polarity of the free charge and the voltage. A charge sensitive preamplifier coupled to a non-contact electrode disposed at a distance from the exposed high resistivity electrode layer outputs a signal in response to movement of free charge within the detector.
FILED Thursday, October 22, 2009
APPL NO 12/604173
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/52
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US 08553384 Darmann
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Francis Anthony Darmann (Chatswood, Australia)
ASSIGNEE(S) Zenergy Power Pty Ltd (Wollongong, Australia)
INVENTOR(S) Francis Anthony Darmann (Chatswood, Australia)
ABSTRACT A fault current limiter (FCL) includes a series of high permeability posts for collectively define a core for the FCL. A DC coil, for the purposes of saturating a portion of the high permeability posts, surrounds the complete structure outside of an enclosure in the form of a vessel. The vessel contains a dielectric insulation medium. AC coils, for transporting AC current, are wound on insulating formers and electrically interconnected to each other in a manner such that the senses of the magnetic field produced by each AC coil in the corresponding high permeability core are opposing. There are insulation barriers between phases to improve dielectric withstand properties of the dielectric medium.
FILED Tuesday, August 23, 2011
APPL NO 13/215647
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/93.500
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US 08553414 Chinthavali
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Madhu Sudhan Chinthavali (Knoxville, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Madhu Sudhan Chinthavali (Knoxville, Tennessee)
ABSTRACT The present invention provides a modular circuit card configuration for distributing heat among a plurality of circuit cards. Each circuit card includes a housing adapted to dissipate heat in response to gas flow over the housing. In one aspect, a gas-cooled inverter includes a plurality of inverter circuit cards, and a plurality of circuit card housings, each of which encloses one of the plurality of inverter cards.
FILED Tuesday, December 06, 2011
APPL NO 13/312548
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/697
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US 08553495 Johnson et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Paul A. Johnson (Santa Fe, New Mexico);  James A. Tencate (Los Alamos, New Mexico);  Pierre-Yves Le Bas (Los Alamos, New Mexico);  Robert Guyer (Reno, Nevada);  Cung Khac Vu (Houston, Texas);  Christopher Skelt (Houston, Texas)
ASSIGNEE(S) Chevron U.S.A. Inc. (San Ramon, California)
INVENTOR(S) Paul A. Johnson (Santa Fe, New Mexico);  James A. Tencate (Los Alamos, New Mexico);  Pierre-Yves Le Bas (Los Alamos, New Mexico);  Robert Guyer (Reno, Nevada);  Cung Khac Vu (Houston, Texas);  Christopher Skelt (Houston, Texas)
ABSTRACT In some aspects of the disclosure, a method and an apparatus is disclosed for investigating material surrounding the borehole. The method includes generating within a borehole an intermittent low frequency vibration that propagates as a tube wave longitudinally to the borehole and induces a nonlinear response in one or more features in the material that are substantially perpendicular to a longitudinal axis of the borehole; generating within the borehole a sequence of high frequency pulses directed such that they travel longitudinally to the borehole within the surrounding material; and receiving, at one or more receivers positionable in the borehole, a signal that includes components from the low frequency vibration and the sequence of high frequency pulses during intermittent generation of the low frequency vibration, to investigate the material surrounding the borehole.
FILED Wednesday, September 29, 2010
APPL NO 12/893573
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/35
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US 08554407 Meisner
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Gregory P. Meisner (Ann Arbor, Michigan)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S) Gregory P. Meisner (Ann Arbor, Michigan)
ABSTRACT Implementing an optimized waste heat recovery system includes calculating a temperature and a rate of change in temperature of a heat exchanger of a waste heat recovery system, and predicting a temperature and a rate of change in temperature of a material flowing through a channel of the waste heat recovery system. Upon determining the rate of change in the temperature of the material is predicted to be higher than the rate of change in the temperature of the heat exchanger, the optimized waste heat recovery system calculates a valve position and timing for the channel that is configurable for achieving a rate of material flow that is determined to produce and maintain a defined threshold temperature of the heat exchanger, and actuates the valve according to the calculated valve position and calculated timing.
FILED Wednesday, September 28, 2011
APPL NO 13/247502
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/36
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US 08554771 Stork
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Christopher Stork (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Christopher Stork (Albuquerque, New Mexico)
ABSTRACT A fast and efficient technique for hierarchical clustering of samples in a dataset includes compressing the dataset to reduce a number of variables within each of the samples of the dataset. A nearest neighbor matrix is generated to identify nearest neighbor pairs between the samples based on differences between the variables of the samples. The samples are arranged into a hierarchy that groups the samples based on the nearest neighbor matrix. The hierarchy is rendered to a display to graphically illustrate similarities or differences between the samples.
FILED Monday, December 14, 2009
APPL NO 12/636898
ART UNIT 2158 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/737
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National Science Foundation (NSF) 

US 08549915 Schofield et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Adam Schofield (Irvine, California);  Alexander Trusov (Irvine, California);  Andrei Shkel (Irvine, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Adam Schofield (Irvine, California);  Alexander Trusov (Irvine, California);  Andrei Shkel (Irvine, California)
ABSTRACT A z-axis gyroscope design is presented with a 2-degree of freedom (DOF) sense mode allowing interchangeable operation in either precision (mode-matched) or robust (wide-bandwidth) modes. This is accomplished using a complete 2-DOF coupled system which allows for the specification of the sense mode resonant frequencies and coupling independent of frequency. By decoupling the frame connecting the sense system to a central anchor, x-y symmetry is preserved while enabling a fully coupled 2-DOF sense mode providing control over both the bandwidth and the amount of coupling independent of operational frequency. The robust mode corresponds to operation between the 2-DOF sense mode resonant frequencies providing a response gain and bandwidth controlled by frequency spacing. Precision mode of operation, however, relies on mode-matching the drive to the second, anti-phase sense mode resonant frequency which can be designed to provide a gain advantage over a similar 1-DOF system.
FILED Friday, October 23, 2009
APPL NO 12/605178
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/504.120
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US 08549925 Tai et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Yu-Chong Tai (Pasadena, California);  Po-Jui Chen (Cupertino, California);  Damien C. Rodger (South Pasadena, California);  Mark S. Humayun (Glendale, California)
ABSTRACT A variable capacitor, a microfabricated implantable pressure sensor including a variable capacitor and an inductor, and related pressure measurement and implantation methods. The inductor may have a fixed or variable inductance. A variable capacitor and pressure sensors include a flexible member that is disposed on a substrate and defines a chamber. Capacitor elements extend indirectly from the flexible member. Sufficient fluidic pressure applied to an exterior surface of the flexible member causes the flexible member to move or deform, thus causing the capacitance and/or inductance to change. Resulting changes in resonant frequency or impedance can be detected to determine pressure, e.g., intraocular pressure.
FILED Monday, November 19, 2012
APPL NO 13/680762
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/754
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US 08550372 Shedd et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Timothy A. Shedd (Madison, Wisconsin);  Adam G. Pautsch (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Timothy A. Shedd (Madison, Wisconsin);  Adam G. Pautsch (Madison, Wisconsin)
ABSTRACT A cooling system and method that significantly improves spray evaporative cooling by using arrays of slot or plane sprays to create coverage of the entire heated surface to be cooled without allowing interaction between plumes that are spraying from the nozzles. The sprays are directed at an angle to the surface to take advantage of the high droplet momentum possessed by the spray to direct a flow of coolant fluid across the surface toward desired draining points, thereby enabling drainage regardless of the orientation of the unit.
FILED Wednesday, March 02, 2005
APPL NO 11/070683
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Fluid sprinkling, spraying, and diffusing
239/11
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US 08550698 Pfeffer et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Robert Pfeffer (Scottsdale, Arizona);  Jose A. Quevedo (Brick, New Jersey);  Juergen Flesch (Rayong, Thailand)
ASSIGNEE(S) Orion Engineered Carbons GmbH (Frankfurt am Main, Germany);  New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) Robert Pfeffer (Scottsdale, Arizona);  Jose A. Quevedo (Brick, New Jersey);  Juergen Flesch (Rayong, Thailand)
ABSTRACT Methods and systems for enhancing fluidization of nanoparticle and/or nanoagglomerates and for mixing and blending nanoparticle/nanoagglomerate systems at the nanoscale are provided. A fluidization chamber is provided with a fluidizing medium (e.g., a fluidizing gas) directed in a first fluidizing direction, e.g., upward into and through a bed containing a volume of nanoparticles and/or nanopowders. A second source of air/gas flow is provided with respect to the fluidization chamber, the secondary air/gas flow generally being oppositely (or substantially oppositely) directed relative to the fluidizing medium. Turbulence created by the secondary gas flow, e.g., a jet from a micro jet nozzle, is advantageously effective to aerate the agglomerates and the shear generated by the jet is advantageously effective to break apart nanoagglomerates and/or reduce the tendency for nanoagglomerates to form or reform. A downwardly directed source of secondary gas flow located near the main gas distributor leads to full fluidization of the entire amount of powder in the column. In addition, the oppositely directed fluid flow facilitates powder circulation within the fluidization chamber, thereby enhancing fluidization and mixing/blending results.
FILED Friday, November 09, 2007
APPL NO 11/937787
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Agitating
366/348
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US 08551390 Jun et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Ho-Wook Jun (Hoover, Alabama);  Ajay Tambralli (Birmingham, Alabama);  Bryan Adam Blakeney (Gulfport, Mississippi);  Derrick Dean (Montgomery, Alabama)
ASSIGNEE(S) The UAB Foundation (Birmingham, Alabama)
INVENTOR(S) Ho-Wook Jun (Hoover, Alabama);  Ajay Tambralli (Birmingham, Alabama);  Bryan Adam Blakeney (Gulfport, Mississippi);  Derrick Dean (Montgomery, Alabama)
ABSTRACT Embodiments of the present disclosure provide electrospinning devices, methods of use, uncompressed fibrous mesh, and the like, are disclosed.
FILED Thursday, April 07, 2011
APPL NO 13/081820
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/465
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US 08551396 Shivaram et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Bellave S. Shivaram (Charlottesville, Virginia);  Adam B. Phillips (Toledo, Ohio)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Bellave S. Shivaram (Charlottesville, Virginia);  Adam B. Phillips (Toledo, Ohio)
ABSTRACT Provided herein are materials that can achieve up to 14% hydrogen absorption by weight in ambient conditions, which is a marked improvement over the hydrogen absorption values found in the prior art. Further provided are experimental conditions necessary to produce these materials. In order to produce the hydrogen storage material, a transition metal (or Lithium) is vaporized in a pi bond gas in conditions that permit only a few bonding collisions to occur between the vaporized transition metal atoms and pi bond gas molecules before the resulting bonded material is collected.
FILED Friday, April 18, 2008
APPL NO 12/595978
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Alloys or metallic compositions
420/8
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US 08551599 Hua et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Zhishan Hua (Raleigh, North Carolina);  Erdogan Gulari (Ann Arbor, Michigan);  Mark A. Burns (Ann Arbor, Michigan);  Rohit Pal (Fishkill, New York);  Onnop Srivannavit (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Zhishan Hua (Raleigh, North Carolina);  Erdogan Gulari (Ann Arbor, Michigan);  Mark A. Burns (Ann Arbor, Michigan);  Rohit Pal (Fishkill, New York);  Onnop Srivannavit (Ann Arbor, Michigan)
ABSTRACT A microactuator may be configured by activating a source of electromagnetic radiation to heat and melt a selected set of phase-change plugs embedded in a substrate of the microactuator, pressurizing a common pressure chamber adjacent to each of the plugs to deform the melted plugs, and deactivating the source of electromagnetic radiation to cool and solidify the melted plugs.
FILED Monday, August 31, 2009
APPL NO 12/551071
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/138
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US 08551725 Leadbetter et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Jared Leadbetter (Altadena, California);  Jean J. Huang (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jared Leadbetter (Altadena, California);  Jean J. Huang (Pasadena, California)
ABSTRACT Screening assays that allow for the identification of agents that increase acyl homoserine lactone (AHL) acylase expression and/or AHL acylase activity in γ-proteobacteria such as Pseudomonas aeruginosa. Such agents are useful, for example, for inhibiting quorum sensing activity of such bacteria by increasing degradation of long chain, but not short chain, AHLs and, therefore, can be useful for treating infections by such bacteria.
FILED Thursday, January 24, 2008
APPL NO 12/019593
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/18
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US 08551730 Azucena et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) Oscar Azucena (Santa Cruz, California);  Joel Kubby (Santa Cruz, California);  Jian Cao (Stanford, California);  William Sullivan (Santa Cruz, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Oscar Azucena (Santa Cruz, California);  Joel Kubby (Santa Cruz, California);  Jian Cao (Stanford, California);  William Sullivan (Santa Cruz, California)
ABSTRACT Methods of microscopic imaging of biological tissue using adaptive optics technology to improve the image focus and sharpness. Wavefront measurements are taken by using a novel method of seeding biological tissue by using a fluorescent microsphere as a “guide star” as a natural point-source reference. The current methods are capable of improving the Strehl ratio of modern biological microscopes as much as 15 times.
FILED Saturday, October 24, 2009
APPL NO 12/605325
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/40.500
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US 08551781 Rome et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) Leonard H. Rome (Tarzana, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Glen R. Nemerow (La Jolla, California);  Cheng-Yu Lai (La Jolla, California);  Christopher M. Wiethoff (Downers Grove, Illinois);  Mu Ri Han (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Leonard H. Rome (Tarzana, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Glen R. Nemerow (La Jolla, California);  Cheng-Yu Lai (La Jolla, California);  Christopher M. Wiethoff (Downers Grove, Illinois);  Mu Ri Han (Los Angeles, California)
ABSTRACT The invention relates to compositions of vault complexes containing recombinant membrane lytic proteins, such as an adenovirus protein VI lytic domain, and methods of using the vault complexes to facilitate delivery and entry of a biomolecule into a cell or subject.
FILED Friday, November 19, 2010
APPL NO 12/950994
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
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US 08551919 Bais et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
APPLICANT(S) Harsh Bais (Newark, Delaware);  Thimmaraju Rudrappa (Hyderabad, India)
ASSIGNEE(S) University of Delaware (Newark, Delaware)
INVENTOR(S) Harsh Bais (Newark, Delaware);  Thimmaraju Rudrappa (Hyderabad, India)
ABSTRACT A method for promoting the health of a plant comprises administering malic acid to the plant or the soil in an amount effective to recruit plant growth promoting rhizobacteria (PGPR) to the plant. Administration of malic acid promotes biofilm formation of PGPR on the plant's roots, thereby restricting entry of a foliar pathogen through stomatal pores present in the leaves. Another method for promoting the health of a plant comprises administering acetoin to the plant or the soil in an amount effective to increase pathogen resistance in aerial parts of the plant.
FILED Monday, April 12, 2010
APPL NO 12/758361
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Plant protecting and regulating compositions
54/307
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US 08552118 Kennedy et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Joseph P. Kennedy (Akron, Ohio);  Yongmoon Kwon (Copley, Ohio);  Subramanyam Ummadisetty (Hattiesburg, Mississippi)
ASSIGNEE(S) The University of Akron (Akron, Ohio)
INVENTOR(S) Joseph P. Kennedy (Akron, Ohio);  Yongmoon Kwon (Copley, Ohio);  Subramanyam Ummadisetty (Hattiesburg, Mississippi)
ABSTRACT The present invention generally relates to alcohol-terminated polyisobutylene (PIB) compounds, and to a process for making such compounds. In one embodiment, the present invention relates to primary alcohol-terminated polyisobutylene compounds, and to a process for making such compounds. In still another embodiment, the present invention relates to polyisobutylene compounds that can be used to synthesize polyurethanes, to polyurethane compounds made via the use of such polyisobutylene compounds, and to processes for making such compounds. In yet another embodiment, the present invention relates to primary alcohol-terminated polyisobutylene compounds having two or more primary alcohol termini and to a process for making such compounds. In yet another embodiment, the present invention relates to primary terminated polyisobutylene compounds having two or more primary termini selected from amine groups or methacrylate groups.
FILED Friday, November 30, 2007
APPL NO 12/516270
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
525/244
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US 08552131 Gleason et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Karen K. Gleason (Cambridge, Massachusetts);  Jingjing Xu (Cambridge, Massachusetts)
ABSTRACT Disclosed is a substantially alternating copolymer that is conformal, hard, flexible, and has low oxygen permeability. Also disclosed is an iCVD-based method of coating a substrate with the substantially alternating copolymer.
FILED Tuesday, February 12, 2013
APPL NO 13/764940
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
526/271
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US 08552143 Puskas et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Judit E. Puskas (Akron, Ohio);  Emily Q. Rosenthal (Akron, Ohio)
ASSIGNEE(S) The University of Akron (Akron, Ohio)
INVENTOR(S) Judit E. Puskas (Akron, Ohio);  Emily Q. Rosenthal (Akron, Ohio)
ABSTRACT High molecular weight disulfide polymers are synthesized in aqueous media by exposing dithiol compounds to a mild oxidizing environment in the presence of a tertiary amine catalyst. The unique oxidizing system polymerizes monomers through the formation of sulfur-sulfur bonds between dithiol compounds. The same oxidizing system may be used to make disulfide-crosslinked gels from compounds containing multiple thiol groups. The oxidizing system is comprised of oxygen at atmospheric concentration and dilute hydrogen peroxide. A filler such as carbon black may be incorporated into the polymer or cross-linked gel during polymerization. A polydisulfide polymer is provided having a weight average molecular weight of greater than about 100,000 g/mol and a polydispersity index of about 2 or less. A tetrathiol composition results from a reaction of a diacrylate with a trithiol. The tetrathiol composition may be subjected to an oxidizing environment with a tertiary amine catalyst to provide a polytetrathiol polymer network.
FILED Friday, March 04, 2011
APPL NO 13/041304
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
528/374
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US 08552299 Rogers et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Materials Sciences and Engineering Division (MSE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) John A. Rogers (Champaign, Illinois);  Yonggang Huang (Glencoe, Illinois);  Heung Cho Ko (Urbana, Illinois);  Mark Stoykovich (Dover, New Hampshire);  Won Mook Choi (Champaign, Illinois);  Jizhou Song (Miami, Florida);  Jong Hyun Ahn (Gyeonggi-do, South Korea);  Dae Hyeong Kim (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) John A. Rogers (Champaign, Illinois);  Yonggang Huang (Glencoe, Illinois);  Heung Cho Ko (Urbana, Illinois);  Mark Stoykovich (Dover, New Hampshire);  Won Mook Choi (Champaign, Illinois);  Jizhou Song (Miami, Florida);  Jong Hyun Ahn (Gyeonggi-do, South Korea);  Dae Hyeong Kim (Champaign, Illinois)
ABSTRACT Disclosed herein are stretchable, foldable and optionally printable, processes for making devices and devices such as semiconductors, electronic circuits and components thereof that are capable of providing good performance when stretched, compressed, flexed or otherwise deformed. Strain isolation layers provide good strain isolation to functional device layers. Multilayer devices are constructed to position a neutral mechanical surface coincident or proximate to a functional layer having a material that is susceptible to strain-induced failure. Neutral mechanical surfaces are positioned by one or more layers having a property that is spatially inhomogeneous, such as by patterning any of the layers of the multilayer device.
FILED Thursday, March 05, 2009
APPL NO 12/398811
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Conductors and insulators
174/254
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US 08552759 Wessels et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Bruce W. Wessels (Wilmette, Illinois);  Nikhil Rangaraju (Elkgrove Village, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Bruce W. Wessels (Wilmette, Illinois);  Nikhil Rangaraju (Elkgrove Village, Illinois)
ABSTRACT In one aspect, the invention relates to programmable logic that utilizes one or more of magnetic diodes. By changing magnetic fields generated in the magnetic diodes due to input signals, the programmable logic can be changed from one logic gate to another logic gate. The unique feature leads to field reprogrammable logic devices in which simple instructions can be used to construct a whole new set of logic gates.
FILED Wednesday, June 20, 2012
APPL NO 13/528505
ART UNIT 2819 — Semiconductors/Memory
CURRENT CPC
Electronic digital logic circuitry
326/38
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US 08553333 Chang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Chemical and Transport Systems (CTS)
U.S. State Government
State of Oregon
APPLICANT(S) Chih-hung Chang (Corvallis, Oregon);  Seung-Yeol Han (Corvallis, Oregon);  Brian K. Paul (Corvallis, Oregon)
ASSIGNEE(S) State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Chih-hung Chang (Corvallis, Oregon);  Seung-Yeol Han (Corvallis, Oregon);  Brian K. Paul (Corvallis, Oregon)
ABSTRACT Embodiments of the present system and method are useful for chemical deposition, particularly continuous deposition of anti-reflective films. Disclosed systems typically comprise a micromixer and a microchannel applicator. A deposition material or materials is applied to a substrate to form a nanostructured, anti-reflective coating. Uniform and highly oriented surface morphologies of films deposited using disclosed embodiments are clearly improved compared to films deposited by a conventional batch process. In some embodiments, a scratch-resistant, anti-reflective coating is applied to a polycarbonate substrate, such as a lens. In certain embodiments, an anti-reflective coating is applied to a surface of a solar catalytic microreactor suitable for performing endothermic reactions, where energy is provided to the reactor by absorption of solar radiation. The composition and morphology of the material deposited on a substrate can be tailored. The process can be used at low temperatures as a post-deposition, high-temperature annealing step is obviated.
FILED Friday, July 22, 2011
APPL NO 13/189411
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/619
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US 08553838 Sommer et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Edward J. Sommer (Nashville, Tennessee);  Robert H. Parrish (Nashville, Tennessee);  David B. Spencer (Bedford, Massachusetts);  Charles E. Roos (Nashville, Tennessee)
ASSIGNEE(S) Sprectramet, LLC (Bedford, Massachusetts)
INVENTOR(S) Edward J. Sommer (Nashville, Tennessee);  Robert H. Parrish (Nashville, Tennessee);  David B. Spencer (Bedford, Massachusetts);  Charles E. Roos (Nashville, Tennessee)
ABSTRACT A system and process for classifying a piece of material of unknown composition at high speeds, where the system connected to a power supply. The piece is irradiated with first x-rays from an x-ray source, causing the piece to fluoresce x-rays. The fluoresced x-rays are detected with an x-ray detector, and the piece of material is classified from the detected fluoresced x-rays. Detecting and classifying may be cumulatively performed in less than one second. An x-ray fluorescence spectrum of the piece of material may be determined from the detected fluoresced x-rays, and the detection of the fluoresced x-rays may be conditioned such that accurate determination of the x-ray fluorescence spectrum is not significantly compromised, slowed or complicated by extraneous x-rays. The piece of material may be classified by recognizing the spectral pattern of the determined x-ray fluorescence spectrum. The piece of material may be flattened prior to irradiation and detection. The x-ray source may irradiate the first x-rays at a high intensity, and the x-ray source may be an x-ray tube.
FILED Tuesday, May 24, 2011
APPL NO 13/114223
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/45
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US 08554031 Astratov
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Vasily N. Astratov (Charlotte, North Carolina)
ASSIGNEE(S) University of North Carolina at Charlotte (Charlotte, North Carolina)
INVENTOR(S) Vasily N. Astratov (Charlotte, North Carolina)
ABSTRACT The present invention provides an optical microprobe device and method for focusing multimodal radiation with wavelength-scale spatial resolution and delivering the focused radiation to a specimen, including: a radiation source; and one or more of a plurality of optically transparent or semitransparent spheres and a plurality of optically transparent or semitransparent cylinders optically coupled to the radiation source; wherein the one or more of the plurality of optically transparent or semitransparent spheres and the plurality of optically transparent or semitransparent cylinders periodically focus radiation optically transmitted from the radiation source such that radiation ultimately transmitted to the specimen has predetermined characteristics. Preferably, the spheres or cylinders are assembled inside one of a hollow waveguide, a hollow-core photonic crystal fiber, a capillary tube, and integrated in a multimode fiber. Alternatively, the spheres or cylinders are assembled on a substrate. Optionally, the optical microprobe device also includes one or more of a waveguide, an optical fiber, a lens, and an optical structure disposed between the radiation source and the spheres or cylinders. Optionally, the spheres or cylinders are made from optically nonlinear or active materials that permit efficient nonlinear frequency generation and low-threshold lasing using the optical microprobe device.
FILED Tuesday, June 08, 2010
APPL NO 13/321965
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/35
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US 08554490 Tang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Mathematical Sciences (DMS)
APPLICANT(S) Dalin Tang (Shrewsbury, Massachusetts);  Zhongzhao Teng (Lianjiang, China PRC)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Dalin Tang (Shrewsbury, Massachusetts);  Zhongzhao Teng (Lianjiang, China PRC)
ABSTRACT A computer system and method are disclosed for automatically generating a vascular model of a blood vessel to support, for example, identification of mechanical factors corresponding to the blood vessel. The method includes interpolating data points corresponding to a contour of the blood vessel; generating a structural model representing three-dimensional structural characteristics of the blood vessel based on interpolated contours; generating a fluid model representing three-dimensional characteristics of fluid flow within the vessel; and generating a vascular model based on the structural model and the fluid model. The method may also include performing a mechanical analysis of the vascular model to identify a mechanical factor associated with the vessel, for example, a factor associated with a potential plaque rupture within the vessel. Embodiments of the invention are applicable to the diagnosis, assessment, or treatment of cardiovascular diseases.
FILED Thursday, February 18, 2010
APPL NO 13/201946
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
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National Aeronautics and Space Administration (NASA) 

US 08549856 Cepedarizo et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Juan Cepedarizo (Long Beach, California);  Gam B. Ganapathi (La Cresenta, California)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Juan Cepedarizo (Long Beach, California);  Gam B. Ganapathi (La Cresenta, California)
ABSTRACT A method of assembling an energy harvesting system is provided. The method includes coupling at least one energy storage device in flow communication with at least one apparatus that is configured to generate thermal energy and to transfer the thermal energy into at least one fluid stream. The energy storage device is configured to store the fluid stream. Moreover, the method includes coupling at least one fluid transfer device downstream from the energy storage device. The fluid transfer device receives the fluid stream from the energy storage device. A bladeless turbine is coupled in flow communication with the fluid transfer device, wherein the bladeless turbine receives the fluid stream to generate power.
FILED Tuesday, October 12, 2010
APPL NO 12/902883
ART UNIT 3748 — SELECT * FROM codes_techcenter;
CURRENT CPC
Power plants
060/616
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US 08550468 Richard
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) James A. Richard (Grant, Alabama)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) James A. Richard (Grant, Alabama)
ABSTRACT In some implementations, apparatus and methods are provided through which a dynamic cryogenic seal is manufactured. In some implementations, the seal includes a retainer and a spring-seal assembly, the assembly being comprised of a main spring housing and fluorine-containing polymer seals. In some implementations, either a radial seal, or an axial (or “piston seal”) is provided. In some implementations, methods of manufacturing the dynamic cryogenic seal are also provided. In some implementations, the methods include assembling the components while either heated or cooled, taking advantage of thermal expansion and contraction, such that there is a strong interference fit between the components at room temperature. In some implementations, this process ensures that the weaker fluorine-containing polymer seal is forced to expand and contract with the stronger retainer and spring and is under constant preload. In some implementations, the fluorine-containing polymer is therefore fluidized and retained, and can not lift off.
FILED Monday, September 15, 2008
APPL NO 12/210843
ART UNIT 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Seal for a joint or juncture
277/605
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US 08551333 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Adam Yuh Lin (Irvine, California);  Tak Sing Wong (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Adam Yuh Lin (Irvine, California);  Tak Sing Wong (Los Angeles, California)
ABSTRACT A microfluidic device for manipulating particles in a fluid has a device body that defines a main channel therein, in which the main channel has an inlet and an outlet. The device body further defines a particulate diverting channel therein, the particulate diverting channel being in fluid connection with the main channel between the inlet and the outlet of the main channel and having a particulate outlet. The microfluidic device also has a plurality of microparticles arranged proximate or in the main channel between the inlet of the main channel and the fluid connection of the particulate diverting channel to the main channel. The plurality of microparticles each comprises a material in a composition thereof having a magnetic susceptibility suitable to cause concentration of magnetic field lines of an applied magnetic field while in operation. A microfluidic particle-manipulation system has a microfluidic particle-manipulation device and a magnet disposed proximate the microfluidic particle-manipulation device.
FILED Monday, April 07, 2008
APPL NO 12/594179
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/222
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US 08551670 Mittelsteadt et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Cortney K. Mittelsteadt (Wayland, Massachusetts);  William A. Braff (Somerville, Massachusetts)
ASSIGNEE(S) Giner Electrochemical Systems, LLC (Newton, Massachusetts)
INVENTOR(S) Cortney K. Mittelsteadt (Wayland, Massachusetts);  William A. Braff (Somerville, Massachusetts)
ABSTRACT An electrochemical device and methods of using the same. In one embodiment, the electrochemical device may be used as a fuel cell and/or as an electrolyzer and includes a membrane electrode assembly (MEA), an anodic gas diffusion medium in contact with the anode of the MEA, a cathodic gas diffusion medium in contact with the cathode, a first bipolar plate in contact with the anodic gas diffusion medium, and a second bipolar plate in contact with the cathodic gas diffusion medium. Each of the bipolar plates includes an electrically-conductive, chemically-inert, non-porous, liquid-permeable, substantially gas-impermeable membrane in contact with its respective gas diffusion medium, as well as a fluid chamber and a non-porous an electrically-conductive plate.
FILED Wednesday, December 17, 2008
APPL NO 12/317068
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/483
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US 08552396 Frolik et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Goddard Space Flight Center (GSFC)
APPLICANT(S) Jeff Frolik (Essex Junction, Vermont);  Christian Skalka (Burlington, Vermont)
ASSIGNEE(S) The University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S) Jeff Frolik (Essex Junction, Vermont);  Christian Skalka (Burlington, Vermont)
ABSTRACT A ground-based system that provides quasi real-time measurement and collection of snow-water equivalent (SWE) data in remote settings is provided. The disclosed invention is significantly less expensive and easier to deploy than current methods and less susceptible to terrain and snow bridging effects. Embodiments of the invention include remote data recovery solutions. Compared to current infrastructure using existing SWE technology, the disclosed invention allows more SWE sites to be installed for similar cost and effort, in a greater variety of terrain; thus, enabling data collection at improved spatial resolutions. The invention integrates a novel computational architecture with new sensor technologies. The invention's computational architecture is based on wireless sensor networks, comprised of programmable, low-cost, low-powered nodes capable of sophisticated sensor control and remote data communication. The invention also includes measuring attenuation of electromagnetic radiation, an approach that is immune to snow bridging and significantly reduces sensor footprints.
FILED Friday, September 25, 2009
APPL NO 12/566797
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/393
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National Security Agency (NSA) 

US 08552783 Rylov
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Sergey V. Rylov (White Plains, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Sergey V. Rylov (White Plains, New York)
ABSTRACT A programmable delay generator and a cascaded interpolator are provided. The programmable delay generator includes a first delay line and a second delay line, each having a respective plurality of stages of the same number. Each stage of the first line includes a respective delay buffer and has one signal input and one signal output. Each stage of the second line includes a respective selecting element and has two signal inputs, one select input for selecting one of the two signal inputs, and one signal output. The first line and the second line are configured in parallel, are interconnected, and have a same signal propagation direction. Each delay step provided by each stage of the second line is equal to a difference between a delay through one stage of the first line and a delay through one stage of the second line.
FILED Friday, June 10, 2011
APPL NO 13/158079
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Miscellaneous active electrical nonlinear devices, circuits, and systems
327/276
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US 08554536 Adelman et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Steven P. Adelman (Portland, Oregon);  Thomas R. Lehnert (Herndon, Virginia)
ASSIGNEE(S) Verizon Patent and Licensing Inc. (Basking Ridge, New Jersey)
INVENTOR(S) Steven P. Adelman (Portland, Oregon);  Thomas R. Lehnert (Herndon, Virginia)
ABSTRACT A system, method and computer program product are provided for creation of a network training environment that simulates a large network as a training target and using simulation and virtual network technologies together with actual network resources to teach computer network exploitation and computer network attack techniques in training exercises for persons responsible for safeguarding networks and for probing and attacking others' networks. The system, method, and computer program product further support integration of real hosts for more realistic exercises.
FILED Thursday, December 21, 2006
APPL NO 11/614675
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/27
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US 08555240 Bouillet et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New York);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Eric Bouillet (Englewood, New Jersey);  Mark D. Feblowitz (Winchester, Massachusetts);  Zhen Liu (Tarrytown, New York);  Anand Ranganathan (Stamford, Connecticut);  Anton V. Riabov (Ossining, New York)
ABSTRACT A method, including: providing a computer menu from which a processing goal can be created, wherein the menu includes a plurality of facets, and wherein each facet includes at least one tag; receiving a processing goal, wherein the processing goal includes a plurality of tags selected from the menu; executing at least one application that includes a plurality of components arranged in a processing graph to produce information that satisfies the processing goal; and outputting the information.
FILED Wednesday, October 15, 2008
APPL NO 12/252132
ART UNIT 2198 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Data processing: Software development, installation, and management
717/101
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Department of Agriculture (USDA) 

US 08551705 Robl et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) James M Robl (Belchertown, Massachusetts);  Pedro Moreira (Sunderland, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) James M Robl (Belchertown, Massachusetts);  Pedro Moreira (Sunderland, Massachusetts)
ABSTRACT Methods for propagating haploid genomes of male or female origina and genetic screening and modification thereof are provided. These haploid genomes may be used to produce haploid embryos, and embryonic stem-like cells and differentiated cells. Also, these haploid genomes and cells containing, may be used as nuclear transfer donors to produce diploid nuclear transfer units. These diploid NT units e.g., human NT units, may be used to obtain pluripotent cells and differentiated cells and tissues.
FILED Friday, January 28, 2011
APPL NO 13/015968
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.120
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US 08552081 Boyles et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) David A. Boyles (Rapid City, South Dakota);  Mohammad S. Al-Omar (Rapid City, South Dakota)
ASSIGNEE(S) South Dakota School of Mines and Technology (Rapid City, South Dakota)
INVENTOR(S) David A. Boyles (Rapid City, South Dakota);  Mohammad S. Al-Omar (Rapid City, South Dakota)
ABSTRACT The present invention is a high modulus bio-based polymer plastic composition or mixture and methods of preparing the same. The composition is formed from the reaction of a bio-based epoxidized triglyceride oil, an energy activated catalyst and a bio-based non-aromatic cross-linking compound to form a structural polymer plastic. The bio-based epoxidized triglyceride oil is selected from a bio-based epoxidized triglyceride or a bio-based acrylated epoxidized triglyceride. The non-aromatic cross-linking compound is selected from itaconic acid or itaconic anhydride, and the energy activated catalyst is activated by UV radiation or heat.
FILED Wednesday, June 04, 2008
APPL NO 12/133272
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
522/24
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U.S. State Government 

US 08552167 Chang et al.
FUNDED BY
U.S. State Government
State of Arizona
APPLICANT(S) Yung Chang (Tempe, Arizona);  Hao Yan (Chandler, Arizona)
ASSIGNEE(S) Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Yung Chang (Tempe, Arizona);  Hao Yan (Chandler, Arizona)
ABSTRACT The present invention provides compositions comprising a ligand-nucleic acid nanostructure that promote tumor cell-specific killing and methods of using the compositions. Specially, the invention provides aptamer-nucleic acid nanostructures for treating tumors in a mammal. The methods of making the compositions are also provided.
FILED Thursday, October 07, 2010
APPL NO 13/392735
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
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US 08553333 Chang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Chemical and Transport Systems (CTS)
U.S. State Government
State of Oregon
APPLICANT(S) Chih-hung Chang (Corvallis, Oregon);  Seung-Yeol Han (Corvallis, Oregon);  Brian K. Paul (Corvallis, Oregon)
ASSIGNEE(S) State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Chih-hung Chang (Corvallis, Oregon);  Seung-Yeol Han (Corvallis, Oregon);  Brian K. Paul (Corvallis, Oregon)
ABSTRACT Embodiments of the present system and method are useful for chemical deposition, particularly continuous deposition of anti-reflective films. Disclosed systems typically comprise a micromixer and a microchannel applicator. A deposition material or materials is applied to a substrate to form a nanostructured, anti-reflective coating. Uniform and highly oriented surface morphologies of films deposited using disclosed embodiments are clearly improved compared to films deposited by a conventional batch process. In some embodiments, a scratch-resistant, anti-reflective coating is applied to a polycarbonate substrate, such as a lens. In certain embodiments, an anti-reflective coating is applied to a surface of a solar catalytic microreactor suitable for performing endothermic reactions, where energy is provided to the reactor by absorption of solar radiation. The composition and morphology of the material deposited on a substrate can be tailored. The process can be used at low temperatures as a post-deposition, high-temperature annealing step is obviated.
FILED Friday, July 22, 2011
APPL NO 13/189411
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/619
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Central Intelligence Agency (CIA) 

US 08555130 Baptist et al.
FUNDED BY
Central Intelligence Agency (CIA)
APPLICANT(S) Andrew Baptist (Chicago, Illinois);  Ilya Volvovski (Chicago, Illinois);  Wesley Leggette (Oak Park, Illinois);  Greg Dhuse (Chicago, Illinois);  Jason K. Resch (Chicago, Illinois)
ASSIGNEE(S) Cleversafe, Inc. (Chicago, Illinois)
INVENTOR(S) Andrew Baptist (Chicago, Illinois);  Ilya Volvovski (Chicago, Illinois);  Wesley Leggette (Oak Park, Illinois);  Greg Dhuse (Chicago, Illinois);  Jason K. Resch (Chicago, Illinois)
ABSTRACT A method begins by a processing module receiving a write request that includes a batch of encoded data slices and a corresponding batch of slice names, wherein the batch of encoded data slices includes encoded data slices that have slices names that have a common data object storage name, a common slice storage name, and a different data segment storage name. The method continues with the processing module determining whether a storage file exists based on the common data object storage name. The method continues with the processing module creating the storage file based on the common data object storage name when the storage file does not exist. The method continues with the processing module storing the batch of encoded data slices in the storage file based on the corresponding batch of slice names.
FILED Tuesday, October 04, 2011
APPL NO 13/252340
ART UNIT 2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/752
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Department of Commerce (DOC) 

US 08554009 Zong et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S) Yuqin Zong (Gaithersburg, Maryland);  Steven W. Brown (Washington Grove, Maryland);  Keith R. Lykke (Gaithersburg, Maryland);  Yoshihiro Ohno (North Potomac, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of Commerce (NIST) (Washington, District of Columbia)
INVENTOR(S) Yuqin Zong (Gaithersburg, Maryland);  Steven W. Brown (Washington Grove, Maryland);  Keith R. Lykke (Gaithersburg, Maryland);  Yoshihiro Ohno (North Potomac, Maryland)
ABSTRACT A simple matrix method and computer program product for stray-light correction in imaging instruments is provided. The stray-light correction method includes receiving raw signals from an imaging instrument and characterizing the imaging instrument for a set of point spread functions. For high resolution imaging instruments, the raw signals may be compressed to reduce the size of the correction matrix. Based on stray-light distribution functions derived from the point spread functions, a correction matrix is derived. This fast correction is performed by a matrix multiplication to the measured raw signals, and may reduce stray-light errors by more than one order of magnitude. Using the stray-light corrected instrument, significant reductions may be made in overall measurement uncertainties in radiometry, colorimetry, photometry and other applications. Because the PSFs may include other types of undesired responses, the stray-light correction also eliminates other types of errors, e.g., interreflection between a CCD and the detector window.
FILED Wednesday, August 13, 2008
APPL NO 12/228495
ART UNIT 2877 — Optics
CURRENT CPC
Image analysis
382/274
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Department of Homeland Security (DHS) 

US 08551714 Jovanovich et al.
FUNDED BY
Department of Homeland Security (DHS)
Homeland Security Advanced Research Projects Agency (HSARPA)
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Stevan Bogdan Jovanovich (Livermore, California);  Iuliu Ioan Blaga (Fremont, California)
ASSIGNEE(S) IntegenX Inc. (Pleasanton, California)
INVENTOR(S) Stevan Bogdan Jovanovich (Livermore, California);  Iuliu Ioan Blaga (Fremont, California)
ABSTRACT Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such as DNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.
FILED Monday, February 06, 2012
APPL NO 13/367326
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
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National Geospatial Intelligence Agency (NGA) 

US 08553989 Owechko et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Yuri Owechko (Newbury Park, California);  Swarup Medasani (Thousand Oaks, California);  Jim Nelson (Sumner, Washington)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Yuri Owechko (Newbury Park, California);  Swarup Medasani (Thousand Oaks, California);  Jim Nelson (Sumner, Washington)
ABSTRACT The present invention relates to a method for three-dimensional (3D) object recognition using region of interest geometric features. The method includes acts of receiving an implicit geometry representation regarding a three-dimensional (3D) object of interest. A region of interest (ROI) is centered on the implicit geometry representation such that there is at least one intersection area between the ROI and the implicit geometry representation. Object shape features are calculated that reflect a location of the ROI with respect to the implicit geometry representation. The object shape features are assembled into a feature vector. A classification confidence value is generated with respect to a particular object classification. Finally, the 3D object of interest is classified as a particular object upon the output of a statistical classifier reaching a predetermined threshold.
FILED Tuesday, April 27, 2010
APPL NO 12/799618
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/224
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Office of the Director of National Intelligence (ODNI) 

US 08553937 Jelinek et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Research, Development and Engineering Command (RDECOM)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Jan Jelinek (Plymouth, Minnesota);  Sharath Venkatesha (Golden Valley, Minnesota);  Vincent Jacobson (Eden Prairie, Minnesota)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Jan Jelinek (Plymouth, Minnesota);  Sharath Venkatesha (Golden Valley, Minnesota);  Vincent Jacobson (Eden Prairie, Minnesota)
ABSTRACT An apparatus includes a video sensing device, a velocity vector estimator (VVE) coupled to the video sensing device, a controller coupled to the velocity vector estimator, and an orthogonal transfer charge-coupled device (OTCCD) coupled to the controller. The video sensing device transmits a plurality of image frames to the velocity vector estimator. The controller receives a location of an object in a current frame, stores locations of the object in one or more previous frames, predicts a motion trajectory and the predicted location of the object on it in a subsequent frame as a function of the locations of the object in the current frame and the one or more previous frames, and transmits the predicted location of the object to the OTCCD. The OTCCD shifts its image array of pixels as a function of the predicted location of the object.
FILED Thursday, October 20, 2011
APPL NO 13/277621
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/103
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U.S. Agency for International Development (USAID) 

US 08552064 Doncel
FUNDED BY
U.S. Agency for International Development (USAID)
APPLICANT(S) Gustavo F. Doncel (Norfolk, Virginia)
ASSIGNEE(S) Eastern Virginia Medical School (Norfolk, Virginia)
INVENTOR(S) Gustavo F. Doncel (Norfolk, Virginia)
ABSTRACT The present invention is directed to methods of inhibiting STDs by topically administering suramin or a derivative thereof to actual or potential sites of infection, and methods of preventing pregnancy by topically applying suramin or a derivative thereof intravaginally. Suramin compositions that include an antimicrobial agent and/or a sperm-function inhibitor are also provided and may advantageously be used in the methods of the invention. A method of simultaneously inhibiting STDs and preventing pregnancy is also provided. Devices impregnated or coated with the topical suramin compositions are further disclosed and may be used to apply the compositions described herein.
FILED Friday, December 19, 2008
APPL NO 12/340339
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/577
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 08553945 Zimmerman
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) Robert S. Zimmerman (South Riding, Virginia)
ASSIGNEE(S) The United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Robert S. Zimmerman (South Riding, Virginia)
ABSTRACT Methods and systems for evaluating an imager that produces bi-chrome images from a scanner or a digital imaging device, the bi-chrome images having pixels of a first and second color. In one embodiment, a method for evaluating an imager includes generating an image that contains pixels of a first color and a second color. The image may be analyzed to determine information about particles of the first and second color. The particles may be described as contiguous pixels of the same color, and the particle information may relate to the size and quantity of the particles of each color. The method may further include determining if the image is unacceptable based on the particle information compared to predefined objective criteria.
FILED Friday, September 14, 2012
APPL NO 13/618879
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/112
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08552625 Butler et al.
FUNDED BY
APPLICANT(S) Image Acoustics, Inc. (Cohasset, Massachusetts)
ASSIGNEE(S) Image Acoustics, Inc. (Cohasset, Massachusetts)
INVENTOR(S) John L. Butler (Cohasset, Massachusetts);  Alexander L. Butler (Weymouth, Massachusetts)
ABSTRACT An electro-mechanical transducer provides a very low frequency wide band response by using a quad configuration of piezoelectric cantilevers, providing additive output between the resonant frequencies of the cantilevers and achieves this at great depths under free flooded or oil filled conditions.
FILED Tuesday, September 25, 2012
APPL NO 13/626138
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/0926 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08552905 Jin et al.
FUNDED BY
APPLICANT(S) Michael Y. Jin (San Gabriel, California);  Eric N. Boe (Long Beach, California)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Michael Y. Jin (San Gabriel, California);  Eric N. Boe (Long Beach, California)
ABSTRACT The technology described herein includes a system and/or a method of automated layout of beams. The method includes generating a plurality of boundary positions along boundaries of an image frame. The method further includes determining a start location for a first beam within the plurality of boundary positions based on at least one of a mapping priority, direction of movement of a beam platform, and speed of movement of the beam platform. The method further includes modifying the plurality of boundary positions based on the start location. The method further includes determining a second location for a second beam within the modified plurality of boundary positions based on at least one of a mapping priority, direction of movement of a beam platform, and speed of movement of the beam platform. The method further includes modifying the modified plurality of boundary positions based on the second location.
FILED Friday, February 25, 2011
APPL NO 13/034995
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications: Directive radio wave systems and devices
342/73
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08553455 Tiwari et al.
FUNDED BY
APPLICANT(S) Sandip Tiwari (Ithaca, New York);  Chung Woo Kim (Suwon-si, South Korea)
ASSIGNEE(S) Cornell Research Foundation, Inc. (Ithaca, New York);  Samsung Electronics Co., Ltd. (Gyeonggi-do, South Korea)
INVENTOR(S) Sandip Tiwari (Ithaca, New York);  Chung Woo Kim (Suwon-si, South Korea)
ABSTRACT Mechanical devices having bistable positions are utilized to form switches and memory devices. The devices are actuatable to different positions and may be coupled to a transistor device in various configurations to provide memory devices. Actuation mechanisms include electrostatic methods and heat. In one form, the mechanical device forms a gate for a field effect transistor. In a further form, the device may be a switch that may be coupled to the transistor in various manners to affect its electrical characteristics when on and off. The memory switch in one embodiment comprises side walls formed with tensile or compressive films. A cross point switch is formed from a plurality of intersecting conductive rows and columns of conductors. Actuatable switches are positioned between each intersection of the rows and columns such that each intersection is independently addressable.
FILED Wednesday, September 27, 2006
APPL NO 11/528712
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/174
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08554087 Osterberg
FUNDED BY
APPLICANT(S) Ulf Osterberg (Etna, New Hampshire)
ASSIGNEE(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Ulf Osterberg (Etna, New Hampshire)
ABSTRACT A method for imaging objects through turbid media includes generating a repetitive pulsed light beam under control of a pulse shaper, propagating the light beam through turbid media, and receiving and imaging the light beam at a sensor. Propagation through turbid media causes scattering of the light, and the sensor captures scattered pulses to produce an image. The pulse shaper controls pulse width, frequency, repetition rate and chirp of the generated light pulses according to a feedback signal received from the sensor, to improve image quality. A system for imaging objects through turbid media includes a laser for generating a light beam; a pulse shaper for controlling said light beam, and a sensor, in communication with the pulse shaper, for capturing the image of said light beam through a turbid medium. Pulse width is less than 250 femtoseconds to reduce attenuation of the light beam through the turbid medium.
FILED Friday, September 14, 2007
APPL NO 12/441859
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical communications
398/199
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 08, 2013.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20131008.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital