FedInvent™ Patents
Patent Details for Tuesday, October 29, 2013
This page was updated on Monday, March 27, 2023 at 03:52 AM GMT
Department of Defense (DOD)
| US 08567077 | Wernig et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael C. Wernig (Delta, Pennsylvania); David J. Irwin (Sparks, Maryland); Carol Acoraci (Timonium, Maryland) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Michael C. Wernig (Delta, Pennsylvania); David J. Irwin (Sparks, Maryland); Joseph H. Acoraci (Phoenix, Maryland) |
| ABSTRACT | A system and processes for aligning an antenna boresight from a position which is internal to a structure on which the antenna is mounted is described. The system includes a laser tracking system and a plurality of targets disposed on a surface of the antenna. |
| FILED | Thursday, October 20, 2011 |
| APPL NO | 13/277604 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Geometrical instruments 033/286 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567107 | Bascue et al. |
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| FUNDED BY |
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| APPLICANT(S) | Clyde H. Bascue (Niskayuna, New York); Paul Watson (Niskayuna, New York) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Clyde H. Bascue (Niskayuna, New York); Paul Watson (Niskayuna, New York) |
| ABSTRACT | A chamber cleaning brush for a gun chamber may include a generally cylindrical body; at least three groups of bristles spaced axially apart along the body; and a pivot ring disposed on the body between two of the groups of bristles. The body may include a larger diameter portion and a smaller diameter portion with at least one group of bristles disposed on the larger diameter portion and at least two groups of bristles disposed on the smaller diameter portion. |
| FILED | Friday, November 14, 2008 |
| APPL NO | 12/271074 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/95 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567247 | Shkel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Andrei M. Shkel (Irvine, California); Alexander A. Trusov (Irvine, California); Igor P. Prikhodko (Westminster, California); Sergei A. Zotov (Irvine, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andrei M. Shkel (Irvine, California); Alexander A. Trusov (Irvine, California); Igor P. Prikhodko (Westminster, California); Sergei A. Zotov (Irvine, California) |
| ABSTRACT | A vibratory sensor is fabricated as a three-dimensional batch-micromachined shell adapted to vibrate and support elastic wave propagation and wave precession in the shell or membrane and at least one driving electrode and preferably a plurality of driving electrodes directly or indirectly coupled to the shell to excite and sustain the elastic waves in the shell. The pattern of elastic waves is determined by the configuration of the driving electrode(s). At least one sensing electrode and preferably a plurality of sensing electrodes are provided to detect the precession of the elastic wave pattern in the shell. The rotation of the shell induces precession of the elastic wave pattern in the shell which is usable to measure the rotation angle or rate of the vibratory sensor. |
| FILED | Wednesday, September 29, 2010 |
| APPL NO | 12/893691 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567292 | Park et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bruce J. Park (Camarillo, California); Michael A. Torres (Newbury Park, California); Mark A. Doty (Port Hueneme, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Bruce J. Park (Camarillo, California); Michael A. Torres (Newbury Park, California); Mark A. Doty (Port Hueneme, California) |
| ABSTRACT | A tool for loosening and/or unscrewing a screw in an object. The tool includes a frame dimensioned and configured to receive (or be mounted on) an object having at least one screw removably embedded therein. |
| FILED | Friday, March 26, 2010 |
| APPL NO | 12/732447 |
| ART UNIT | 3727 — Printing/Measuring and Testing |
| CURRENT CPC | Tools 081/462 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567300 | Cler |
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| FUNDED BY |
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| APPLICANT(S) | Daniel L. Cler (Coatesville, Pennsylvania) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel L. Cler (Coatesville, Pennsylvania) |
| ABSTRACT | A bore evacuator for a gun tube may include a time-delayed discharge valve. The time-delayed discharge valve may open substantially simultaneously with the opening of the breech of the gun tube. Gas discharged from the bore evacuator may evacuate the bore of the gun tube. The time delay of the time-delayed discharge valve may be activated by gas pressure in the bore evacuator. The bore evacuator may include a pressure-regulating valve for regulating the maximum pressure in the bore evacuator. |
| FILED | Monday, November 22, 2010 |
| APPL NO | 12/951102 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/1.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567332 | Bassler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Christopher C. Bassler (Arlington, Virginia); Allan Scott Percival (Gaithersburg, Maryland); Martin J. Dipper (Annapolis, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher C. Bassler (Arlington, Virginia); Allan Scott Percival (Gaithersburg, Maryland); Martin J. Dipper (Annapolis, Maryland) |
| ABSTRACT | An advanced bilge keel design for improved ship roll damping performance. The advanced bilge keel design includes curved upper and bottom surfaces and improved free end edge design for providing passive roll stabilization and improved energy dissipation. |
| FILED | Monday, June 27, 2011 |
| APPL NO | 13/169888 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/142 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567403 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ryan P. Lu (San Diego, California); Christopher K. Huynh (Rosemead, California); Ayax D. Ramirez (Chula Vista, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ryan P. Lu (San Diego, California); Christopher K. Huynh (Rosemead, California); Ayax D. Ramirez (Chula Vista, California) |
| ABSTRACT | A system includes an ultraviolet light source, such as light-emitting diodes, disposed between a first ionic grid and a second ionic grid. The first and the second ionic grids have opposite ionic charges and a plurality of silver nanoparticles disposed thereon. The ultraviolet light source is configured to emit, onto the first and the second ionic grids, ultraviolet radiation having a wavelength of between about 100 nm and about 280 nm. A biochemical detector may be located adjacent to the first ionic grid on a side of the first ionic grid opposite the ultraviolet light source. The ultraviolet light source, first ionic grid, and second ionic grid may be located within a housing connected to a gas mask, and a membrane filter may be disposed between the gas mask and housing. The housing may include a power source connected to the ultraviolet light source. |
| FILED | Thursday, May 05, 2011 |
| APPL NO | 13/101747 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery 128/205.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567713 | Cookerly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Al Cookerly (Brownsburg, Indiana); Andrew D. Copeland (Greenwood, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Al Cookerly (Brownsburg, Indiana); Andrew D. Copeland (Greenwood, Indiana) |
| ABSTRACT | A multi-plate clutch is provided to couple a drive shaft from a gas turbine engine with a driven shaft of a lift fan. When disengaged the plates of the clutch can be physically separated. Plates of one shaft are coupled to the shaft with individual energy members that return the plates to a disengaged position. The plates of the other shaft can be coupled together with a travel member and/or lug key and energy devices between at least some of the plates. |
| FILED | Thursday, December 10, 2009 |
| APPL NO | 12/635525 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/60 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567723 | Etzkorn et al. |
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| FUNDED BY |
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| APPLICANT(S) | Karen M. Etzkorn (Edwardsville, Illinois); Eric P. Oman (Lake Saint Louis, Missouri); Dallas S. Scholes (Buckley, Washington) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Karen M. Etzkorn (Edwardsville, Illinois); Eric P. Oman (Lake Saint Louis, Missouri); Dallas S. Scholes (Buckley, Washington) |
| ABSTRACT | An aerial identification and fuel inventory control system is disclosed. An RFID transponder mounted on a refueling aircraft transmits an identifier identifying the refueling aircraft in proximity to a fuel delivery aircraft. Substantially just prior to a start of fueling the refueling aircraft, the identifier is automatically logged in the fuel inventory control system. Upon completion of the fueling, a quantity of off-loaded fuel associated with the identifier is automatically logged in the fuel inventory control system. A fueling report may be automatically generated. |
| FILED | Wednesday, November 18, 2009 |
| APPL NO | 12/620599 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeronautics and astronautics 244/135.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567744 | Marn et al. |
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| FUNDED BY |
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| APPLICANT(S) | William H. Marn (San Diego, California); Brandon J. Wiedemeier (San Diego, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William H. Marn (San Diego, California); Brandon J. Wiedemeier (San Diego, California) |
| ABSTRACT | A reusable device for detachably mounting an object to a platform includes a breakaway plate that is mounted to the object and a mounting bracket that is fixed to the platform. The breakaway plate is formed with a circumferential groove, and an o-ring is placed in the groove. A tooth ring having a slight gap is positioned over the o-ring. As a retaining ring is placed over the o-ring and tooth ring and fastened to the mounting bracket, the tooth ring compresses, which causes the o-ring to compress and engage the tooth ring at a breakaway force of the object. When an applied force that is greater than the breakaway force is applied to the object, the o-ring pops out to separate the object and platform. The o-ring durometer is chosen according to the magnitude of breakaway force that is desired by the user. |
| FILED | Tuesday, January 03, 2012 |
| APPL NO | 13/342348 |
| ART UNIT | 3631 — Static Structures, Supports and Furniture |
| CURRENT CPC | Supports 248/548 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567745 | Wong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joey Wong (Enfield, Connecticut); Constantino V. Loffredo (Newington, Connecticut); Fernando K. Grant (South Windsor, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Joey Wong (Enfield, Connecticut); Constantino V. Loffredo (Newington, Connecticut); Fernando K. Grant (South Windsor, Connecticut) |
| ABSTRACT | A flanged apparatus includes an apparatus body and a flanged mount, which includes a support pylon, a first mounting flange and a second mounting flange. The support pylon includes a first pylon segment, a second pylon segment and a routing notch. The first pylon segment is cantilevered from the apparatus body, and extends to the first mounting flange. The second pylon segment is cantilevered from the first pylon support, and extends from the first mounting flange to the second mounting flange. The routing notch extends vertically between the first pylon segment and the second pylon segment. The first mounting flange and the second mounting flange extend laterally from the support pylon, and the first mounting flange is separated from the second mounting flange by a longitudinal distance and a vertical distance. |
| FILED | Thursday, December 15, 2011 |
| APPL NO | 13/327355 |
| ART UNIT | 3632 — Static Structures, Supports and Furniture |
| CURRENT CPC | Supports 248/554 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567872 | Carr |
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| FUNDED BY |
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| APPLICANT(S) | Jonathan J. Carr (Vienna, Virginia) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Jonathan J. Carr (Vienna, Virginia) |
| ABSTRACT | An apparatus for grinding material includes a grinder bit including a drum and a plurality of grinders, at least a portion of the grinders disposed longitudinally in a first helical pattern along the outer surface of the drum. The apparatus further includes a plurality of cleats, at least a portion of the cleats disposed longitudinally in a second helical pattern along the outer surface of the drum. The second helical pattern is offset from the first helical pattern. |
| FILED | Friday, September 19, 2008 |
| APPL NO | 12/233726 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Mining or in situ disintegration of hard material 299/39.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567969 | Thomas et al. |
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| FUNDED BY |
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| APPLICANT(S) | John A. Thomas (Tucson, Arizona); Thomas H. Lind (Tucson, Arizona); Ronald L. Roncone (Vail, Arizona); Gary H. Johnson (Tucson, Arizona) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | John A. Thomas (Tucson, Arizona); Thomas H. Lind (Tucson, Arizona); Ronald L. Roncone (Vail, Arizona); Gary H. Johnson (Tucson, Arizona) |
| ABSTRACT | Optical systems configured to withstand operation in high acceleration and varying temperature environments, and methods of assembling the same. In one example, an imaging optical apparatus includes a primary minor made of an unreinforced polymer, a secondary mirror made of the unreinforced polymer and optically coupled to the primary minor, a field lens optically coupled to the secondary minor, and a strut having a plurality of cross-struts and mounting features configured to mount the primary minor, the secondary mirror and the field lens. In some examples, the imaging optical apparatus further includes an outer retainer disposed behind the primary minor and coupled to the strut, and an inner retainer disposed behind the field lens and coupled to the strut, the outer and inner retainers configured to structurally support the primary minor and the field lens and to accommodate deflections of the primary minor. |
| FILED | Friday, February 10, 2012 |
| APPL NO | 13/370543 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/850 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568026 | Gregory et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wireless Sensor Technologies, LLC (Encinitas, California) |
| ASSIGNEE(S) | Wireless Sensor Technologies, LLC (Encinitas, California) |
| INVENTOR(S) | Otto J. Gregory (Wakefield, Rhode Island); John R. Conkle (Encinitas, California); Thomas J. Birnbaum (Santa Cruz, California) |
| ABSTRACT | A temperature measurement system capable of operating in harsh environments including a temperature sensor having an antenna, diode, and dielectric layer disposed on the object of interest is provided, wherein the antenna includes a buried portion that extends through and is electrically coupled to the object of interest, and an exposed portion disposed upon an outer surface of the dielectric layer and the diode is coupled between the object of interest and the exposed portion of the antenna. The antenna is configured to receive interrogating signals from a transmitter, and to transmit response signals corresponding to the resonant frequency of the temperature sensor and its harmonics, which are indicative of the measured temperature of the object of interest. A receiver detects the response signals and correlates the frequency to a known temperature response of the dielectric material. Methods of making and using the temperature measurement system are also provided. |
| FILED | Monday, January 07, 2013 |
| APPL NO | 13/735906 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Thermal measuring and testing 374/152 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568039 | Owen, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joseph McLellan Owen, III (Derry, New Hampshire); David Paul Kelly (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Joseph McLellan Owen, III (Derry, New Hampshire); David Paul Kelly (Nashua, New Hampshire) |
| ABSTRACT | A fiber-optic connector for connecting an optical fiber to other optical assemblies is disclosed. The fiber-optic connector includes a top plate having a window of similar refractive index and transmission index as the material of an optic fiber to be contained within the fiber-optic connector. The fiber-optic connector also includes a ferrule connected to the top plate via multiple spring-loaded screws. The ferrule includes an interface and an insert. The insert is capable of firmly gripping an optical fiber. In order to reduce Fresnel reflection losses of the fiber-optic connector, the window is pre-coated with an anti-reflective surface on the side opposite an optic fiber to be contained within the fiber-optic connector. |
| FILED | Monday, June 21, 2010 |
| APPL NO | 12/819421 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/62 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568076 | Harris et al. |
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| FUNDED BY |
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| APPLICANT(S) | Donald B. Harris (Arlington, Virginia); Robert J. Galway (Virginia Beach, Virginia); Brandon Z. Lukert (Virginia Beach, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Donald B. Harris (Arlington, Virginia); Robert J. Galway (Virginia Beach, Virginia); Brandon Z. Lukert (Virginia Beach, Virginia) |
| ABSTRACT | An apparatus for securing and fueling a surface water vessel at a floating receptacle that is towed by a parent ship. The surface water vessel may be a manned or an unmanned surface vehicle, for example. According to the invention, the surface water vessel includes a retractable probe for securing the water vessel to the floating receptacle and also for receiving fuel from the parent ship via the floating receptacle. The floating receptacle has first and second arms pivotally attached to a mounting block, forming a substantially V-shape having an adjustable apex angle. |
| FILED | Thursday, June 21, 2012 |
| APPL NO | 13/529049 |
| ART UNIT | 3617 — Optics |
| CURRENT CPC | Material or article handling 414/137.900 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568121 | Khoshnevis |
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| FUNDED BY |
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| APPLICANT(S) | Behrokh Khoshnevis (Marina del Rey, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Behrokh Khoshnevis (Marina del Rey, California) |
| ABSTRACT | An extrusion construction system may include an extrusion nozzle configured to extrude construction material through an outlet onto an external surface, the extrusion nozzle including an excess flow port disposed substantially adjacent an edge of the outlet, an imaging device coupled to the extrusion nozzle, and a controller configured to adjust the rate of material flow through the extrusion nozzle in response to receiving one or more images captured by the imaging device showing excess material being extruded through the excess flow port. |
| FILED | Monday, November 24, 2008 |
| APPL NO | 12/277176 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Plastic article or earthenware shaping or treating: Apparatus 425/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568145 | Jastrzembski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tiffany S Jastrzembski (Centerville, Ohio); Stuart M Rogers (Dayton, Ohio); Kevin A Gluck (Beavercreek, Ohio); Michael A Krusmark (Phoenix, Arizona) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Tiffany S Jastrzembski (Centerville, Ohio); Stuart M Rogers (Dayton, Ohio); Kevin A Gluck (Beavercreek, Ohio); Michael A Krusmark (Phoenix, Arizona) |
| ABSTRACT | A method, apparatus and program product are provided for optimizing a training regimen to achieve performance goals. Historical training data is provided. At least one training regimen is defined. A training objective is selected for at least one training regimen to optimize. The training regimen is optimized by computing an initial training regimen solution and computing a neighbor solution at a distance from the initial training regimen solution. The neighbor solution is compared to the initial training regimen solution. If the neighbor solution is determined to be a better solution than the initial training regimen solution, the initial training regimen solution is replaced with the neighbor solution. The distance is updated per a schedule to compute a next neighbor solution. |
| FILED | Friday, August 19, 2011 |
| APPL NO | 13/213127 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Education and demonstration 434/219 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568315 | Currie et al. |
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| FUNDED BY |
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| APPLICANT(S) | John F. Currie (Bethesda, Maryland); Makarand Paranjape (Arlington, Virginia); Carl C. Peck (Rockville, Maryland); Robert White (Fairfax, Virginia); Thomas W. Schneider (Gaithersburg, Maryland) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia); Science Applications International Corporation (McLean, Virginia) |
| INVENTOR(S) | John F. Currie (Bethesda, Maryland); Makarand Paranjape (Arlington, Virginia); Carl C. Peck (Rockville, Maryland); Robert White (Fairfax, Virginia); Thomas W. Schneider (Gaithersburg, Maryland) |
| ABSTRACT | The present invention pertains to a system and method for transdermal sampling, comprising: at least one sampler for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject; at least one detector system for identifying and quantifying said at least one analyte; and at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector. |
| FILED | Wednesday, April 13, 2011 |
| APPL NO | 13/085775 |
| ART UNIT | 3777 — Amusement and Education Devices |
| CURRENT CPC | Surgery 6/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568417 | Petrzelka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joseph Petrzelka (Cambridge, Massachusetts); Manas Menon (Boston, Massachusetts); Suresh Agarwal (Hopkinton, Massachusetts); Dimitris Chatzigeorgiou (Somerville, Massachusetts); Michelle Lustrino (Cambridge, Massachusetts); Clara Stefanov-Wagner (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Charles River Engineering Solutions and Technologies, LLC (Marina del Rey, California) |
| INVENTOR(S) | Joseph Petrzelka (Cambridge, Massachusetts); Manas Menon (Boston, Massachusetts); Suresh Agarwal (Hopkinton, Massachusetts); Dimitris Chatzigeorgiou (Somerville, Massachusetts); Michelle Lustrino (Cambridge, Massachusetts); Clara Stefanov-Wagner (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed are embodiments of an articulating tool having a head that articulates and is capable of maintaining an angle for drilling or placing a fastener into a bone. The articulating tool includes a housing, an articulating head, a rotatable drive shaft, and a driver tip connected to the distal shaft portion. The articulating tool may be constructed and arranged to move between a first position and a second position, wherein in the first position and the second position the articulating head and the rotatable drive shaft are at different angles with respect to the longitudinal axis of the housing. |
| FILED | Monday, September 20, 2010 |
| APPL NO | 12/886474 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery 66/80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568542 | Yamamoto et al. |
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| FUNDED BY |
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| APPLICANT(S) | Christina M. Yamamoto (Bloomington, Indiana); Robert G. Shortridge (Bloomfield, Indiana) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christina M. Yamamoto (Bloomington, Indiana); Robert G. Shortridge (Bloomfield, Indiana) |
| ABSTRACT | Perchlorate-free flare compositions are disclosed which, when burned, produce yellow smoke and flames. Methods of producing the compositions are also disclosed. |
| FILED | Friday, December 12, 2008 |
| APPL NO | 12/334101 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568681 | Kouvetakis et al. |
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| FUNDED BY |
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| APPLICANT(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-xSiHx, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
| FILED | Tuesday, July 12, 2011 |
| APPL NO | 13/180961 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568686 | Morse et al. |
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| FUNDED BY |
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| APPLICANT(S) | Daniel E. Morse (Santa Barbara, California); Birgit Schwenzer (Goleta, California); John R. Gomm (Santa Barbara, California); Kristian M. Roth (Bothell, Washington); Brandon Heiken (Goleta, California); Richard Brutchey (Santa Barbara, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel E. Morse (Santa Barbara, California); Birgit Schwenzer (Goleta, California); John R. Gomm (Santa Barbara, California); Kristian M. Roth (Bothell, Washington); Brandon Heiken (Goleta, California); Richard Brutchey (Santa Barbara, California) |
| ABSTRACT | A method for the fabrication of nanostructured semiconducting, photoconductive, photovoltaic, optoelectronic and electrical battery thin films and materials at low temperature, with no molecular template and no organic contaminants. High-quality metal oxide semiconductor, photovoltaic and optoelectronic materials can be fabricated with nanometer-scale dimensions and high dopant densities through the use of low-temperature biologically inspired synthesis routes, without the use of any biological or biochemical templates. |
| FILED | Wednesday, April 18, 2007 |
| APPL NO | 11/737087 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/592.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568832 | Nanna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael E. Nanna (Moorhead, Minnesota); Gordon P. Bierwagen (Fargo, North Dakota); Dante Battocchi (Fargo, North Dakota) |
| ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
| INVENTOR(S) | Michael E. Nanna (Moorhead, Minnesota); Gordon P. Bierwagen (Fargo, North Dakota); Dante Battocchi (Fargo, North Dakota) |
| ABSTRACT | Disclosed are methods of treating a metal to improve the metal's corrosion resistance. The method includes applying, to the surface of the metal, a coating which comprises magnesium powder and a binder. The present invention also relates to a coating composition that includes magnesium powder and a silane modified epoxy isocyanate hybrid polymer or prepolymer. The inventors have found that corrosion resistance (as determined by Prohesion™ exposure in accordance with ASTM D5894-96, which is hereby incorporated by reference) in excess of 3,000 hours on 2024 T-3 aluminum alloy can be achieved with the methods and coating compositions of the present invention. |
| FILED | Thursday, October 07, 2004 |
| APPL NO | 10/579148 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 5/00 (20130101) Original (OR) Class B05D 7/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568877 | Ferrari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugarland, Texas); Ciro Chiappini (Austin, Texas); Jean Raymond Fakhoury (Round Rock, Texas) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugarland, Texas); Ciro Chiappini (Austin, Texas); Jean Raymond Fakhoury (Round Rock, Texas) |
| ABSTRACT | Disclosed are a variety of porous and non-porous wire-like structures of microscopic and nanoscopic scale. For instance, disclosed are structures that comprise a porous object that comprises: (i) a first region; and (ii) a second region adjacent to the first region along an axis of the object, where the first region has at least one porous property different from that of the second region. Also disclosed are structures that include: (i) a high resistivity silicon; and (ii) a cross-section that is substantially perpendicular to an axis of the object. Also disclosed are methods of making and using such structures. For instance, the present invention provides methods of making a porous object by: (i) obtaining an etchable substrate; (ii) forming on a surface of the substrate a patterned porosification assisting metal layer that has at least one opening; and (iii) subsequently exposing the substrate to a first etching solution and a second etching solution to form respectively a first region and a second region of a porous object. |
| FILED | Wednesday, March 09, 2011 |
| APPL NO | 13/044250 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568984 | Su et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ying-Hsiu Su (Audubon, Pennsylvania); Benjamin Song (Audubon, Pennsylvania); Janet Song (Audubon, Pennsylvania); Timothy M. Block (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | Philadelphia Health and Education Corporation (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ying-Hsiu Su (Audubon, Pennsylvania); Benjamin Song (Audubon, Pennsylvania); Janet Song (Audubon, Pennsylvania); Timothy M. Block (Doylestown, Pennsylvania) |
| ABSTRACT | Provided are methods of diagnosing and/or determining treatment of non-urinary tract cancers by detecting biomarkers, and aberrant methylation in said biomarkers, in human urine samples. |
| FILED | Friday, February 18, 2011 |
| APPL NO | 13/030888 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568998 | Mani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sendurai Mani (Cambridge, Massachusetts); Jing Yang (Cambridge, Massachusetts); Robert A. Weinberg (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Sendurai Mani (Cambridge, Massachusetts); Jing Yang (Cambridge, Massachusetts); Robert A. Weinberg (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating, diagnosing, and assisting in the diagnosis of metastasis in an individual, or of determining the metastatic potential of a tumor. The invention further relates to methods of identifying agents which inhibit metastasis. |
| FILED | Thursday, December 01, 2011 |
| APPL NO | 13/309067 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569121 | Haensch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wilfried Ernst-August Haensch (Somers, New York); Zihong Liu (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Wilfried Ernst-August Haensch (Somers, New York); Zihong Liu (Yorktown Heights, New York) |
| ABSTRACT | Transistor devices having a self-aligned gate structure on transparent substrates and techniques for fabrication thereof are provided. In one aspect, a method of fabricating a transistor device includes the following steps. A channel material is formed on a transparent substrate. Source and drain electrodes are formed in contact with the channel material. A dielectric layer is deposited on the channel material. A photoresist is deposited on the dielectric layer and developed using UV light exposure through the transparent substrate. A gate metal(s) is deposited on the exposed portions of the dielectric layer and the undeveloped portions of the photoresist. The undeveloped portions of the photoresist are removed along with portions of the gate metal over the source and drain regions to form a gate of the device on the dielectric layer over the channel material which is self-aligned to the source and drain electrodes. |
| FILED | Tuesday, November 01, 2011 |
| APPL NO | 13/286394 |
| ART UNIT | 2896 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569226 | Krauland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric Mark Krauland (Lebanon, New Hampshire); Stephen Kottmann (Cambridge, Massachusetts); Roberto Juan Barbero (Cambridge, Massachusetts); Angela Belcher (Lexington, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Eric Mark Krauland (Lebanon, New Hampshire); Stephen Kottmann (Cambridge, Massachusetts); Roberto Juan Barbero (Cambridge, Massachusetts); Angela Belcher (Lexington, Massachusetts) |
| ABSTRACT | A dodecamer peptide, and its modified variant, having a repeating glycine-lysine sequence was created and found to bind with high affinity to oxide surfaces and certain activated polymeric surfaces. Reversible binding characteristics of the peptides were demonstrated. The peptides were integrated with proteins, cells and fusion proteins to provide attachment of the proteins, cells and fusion proteins to solid material structures. The peptides can be used to functionalize surfaces of components within mechanical, in mechanical, biomechanical, micro fluidic, electronic, bioelectronic, bio-optical, and biochemical devices. Experiments were carried out to assess functionalization and reusability of a suspended mass resonator's cantilever. |
| FILED | Friday, September 19, 2008 |
| APPL NO | 12/678911 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569399 | Keller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Teddy M Keller (Fairfax Station, Virginia); Matthew Laskoski (Springfield, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Teddy M Keller (Fairfax Station, Virginia); Matthew Laskoski (Springfield, Virginia) |
| ABSTRACT | Disclosed herein is a composition having a thermoset polymer and a plurality of hollow microsphere homogenously dispersed in the composition. The polymer is a cyanate ester thermoset, a phthalonitrile thermoset, a crosslinked acetylene thermoset, or a hydrosilation thermoset. Also disclosed herein is a method of: providing a thermosetting compound; adding microspheres to the thermosetting compound; and mixing the thermosetting compound while initiating crosslinking of the thermosetting compound. |
| FILED | Thursday, September 13, 2012 |
| APPL NO | 13/613152 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 523/218 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569468 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fanqing Frank Chen (Moraga, California); Gang L. Liu (Berkeley, California); Luke P. Lee (Orinda, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Fanqing Frank Chen (Moraga, California); Gang L. Liu (Berkeley, California); Luke P. Lee (Orinda, California) |
| ABSTRACT | This invention provides a nanoplasmonic molecular ruler, which can perform label-free and real-time monitoring of nucleic acid (e.g., DNA) length changes and perform nucleic acid footprinting. In various embodiments the ruler comprises a nucleic acid attached to a nanoparticle, such that changes in the nucleic acid length are detectable using surface plasmon resonance. The nanoplasmonic ruler provides a fast and convenient platform for mapping nucleic acid-protein interactions, for nuclease activity monitoring, and for other footprinting related methods. |
| FILED | Friday, September 14, 2007 |
| APPL NO | 12/440579 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569670 | Carlucci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donald Carlucci (Sparta, New Jersey); David Geissler (Mount Arlington, New Jersey); John Thomas (Morris Plains, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Donald Carlucci (Sparta, New Jersey); David Geissler (Mount Arlington, New Jersey); John Thomas (Morris Plains, New Jersey) |
| ABSTRACT | An advance is made in the art according to an aspect of the present invention disclosure directed to a pressure-activated, inertially locking base and fin mechanism for projectiles. Operationally, a base housing of a projectile contains both the fins, held within slots within the base, and a plunger. Which plunger has plurality of channels communicating with a chamber within base and which plunger is initially situated flush with the base. Upon firing the chamber is pressurized by the high-pressure firing gases being forced through the channels. When the projectile exits the barrel, the chamber's pressure vents through the channels, but, not fast enough to avoid a pressure differential that forces the plunger out of the base, causing a set of spring arms to flex upward and deploy the fins. When fully deployed, the fins are locked in place, in the deployed position, by a spring loaded pin. |
| FILED | Monday, May 21, 2012 |
| APPL NO | 13/476451 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/3.280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569680 | Luke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Geoffrey P. Luke (Austin, Texas); Cameron H. G. Wright (Laramie, Wyoming); Steven F. Barrett (Laramie, Wyoming) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Geoffrey P. Luke (Austin, Texas); Cameron H. G. Wright (Laramie, Wyoming); Steven F. Barrett (Laramie, Wyoming) |
| ABSTRACT | A multi-aperture passive light sensor and method for detecting motion and edges of an object are described. The sensor may include at least two focusing lenses mounted on a spherical surface for focusing light from the object into the ends of optical fibers, the optical axis for each lens diverging at an angle from that of adjacent lenses depending on the intended application. Each lens is located closer to the end of its associated optical fiber, which is disposed coaxially to the optical axis of the lens, than the natural focal plane of the lens, thereby blurring the light received from the object. Light exiting the fibers is detected by photosensors located at the opposite end of each optical fiber, and voltage differences between the voltages generated in response to the light intensity impinging on the photosensors are used to detect motion and edges of the object. |
| FILED | Tuesday, December 21, 2010 |
| APPL NO | 12/975139 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/221 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569695 | Zewail et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ahmed H. Zewail (Pasadena, California); David J. Flannigan (Temple City, California); Brett Barwick (Berlin, Connecticut) |
| ABSTRACT | A method of obtaining PINEM images includes providing femtosecond optical pulse, generating electron pulses, and directing the electron pulses towards a sample. The method also includes overlapping the femtosecond optical pulses and the electron pulses spatially and temporally at the sample and transferring energy from the femtosecond optical pulses to the electron pulses. The method further includes detecting electron pulses having an energy greater than a zero loss value, providing imaging in space and time. |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/863742 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569705 | Baltz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nathan T. Baltz (Boulder, Colorado); J. D. Sheldon Danielson (Boulder, Colorado) |
| ASSIGNEE(S) | TauTheta Instruments LLC (Fort Collins, Colorado) |
| INVENTOR(S) | Nathan T. Baltz (Boulder, Colorado); J. D. Sheldon Danielson (Boulder, Colorado) |
| ABSTRACT | Methods and apparatus for system identification operate by computing phase and amplitude using linear filters. By digitally processing the linearly filtered signals or data, the phase and amplitude based on measurements of the input and output of a system, are determined. |
| FILED | Friday, September 03, 2010 |
| APPL NO | 12/875917 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/362 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569720 | Rigney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nickolas S. Rigney (Redlands, California); Daniel C. Anderson (Loma Linda, California); David A. Lesyna (Redlands, California); Daniel W. Miller (Oriental, North Carolina); Michael F. Moyers (Colton, California); Chieh C. Cheng (Redlands, California); Michael A. Baumann (Riverside, California) |
| ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
| INVENTOR(S) | Nickolas S. Rigney (Redlands, California); Daniel C. Anderson (Loma Linda, California); David A. Lesyna (Redlands, California); Daniel W. Miller (Oriental, North Carolina); Michael F. Moyers (Colton, California); Chieh C. Cheng (Redlands, California); Michael A. Baumann (Riverside, California) |
| ABSTRACT | A patient alignment system for a radiation therapy system. The alignment system includes multiple external measurement devices which obtain position measurements of components of the radiation therapy system which are movable and/or are subject to flex or other positional variations. The alignment system employs the external measurements to provide corrective positioning feedback to more precisely register the patient and align them with a radiation beam. The alignment system can be provided as an integral part of a radiation therapy system or can be added as an upgrade to existing radiation therapy systems. |
| FILED | Friday, August 24, 2012 |
| APPL NO | 13/594630 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/492.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569739 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Seheon Kim (Pasadena, California); Axel Scherer (Woodstock, Vermont); Jingqing Huang (Pasadena, California); Dong Yoon Oh (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Seheon Kim (Pasadena, California); Axel Scherer (Woodstock, Vermont); Jingqing Huang (Pasadena, California); Dong Yoon Oh (Pasadena, California) |
| ABSTRACT | A method of etching active quantum nanostructures provides the step of laterally etching of an intermediate active quantum nanostructure layer interposed between cladding layers. The lateral etching can be carried out on at least one side of the intermediate active quantum nanostructure layer selectively, with respect to the cladding layers to define at least one lateral recess or spacing in the intermediate active quantum nanostructure layer and respective lateral protrusions of cladding layers protruding with respect to the intermediate active quantum nanostructure layer. This method can be applied to create devices including active quantum nanostructures such as, for example, three-dimensional photonic crystals, a photonic crystal double-slab and a photonic crystal laser. |
| FILED | Thursday, December 08, 2011 |
| APPL NO | 13/314688 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569741 | Scherer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Axel Scherer (Laguna Beach, California); Sameer Walavalkar (Los Angeles, California); Michael D. Henry (Altadena, California); Andrew P. Homyk (South Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Axel Scherer (Laguna Beach, California); Sameer Walavalkar (Los Angeles, California); Michael D. Henry (Altadena, California); Andrew P. Homyk (South Pasadena, California) |
| ABSTRACT | Methods for fabricating passivated silicon nanowires and an electronic arrangement thus obtained are described. Such arrangements may comprise a metal-oxide-semiconductor (MOS) structure such that the arrangements may be utilized for MOS field-effect transistors (MOSFETs) or opto-electronic switches. |
| FILED | Monday, October 31, 2011 |
| APPL NO | 13/286008 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569941 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wanli Yang (El Cerrito, California); Jason D. Fabbri (San Francisco, California); Nicholas A. Melosh (Menlo Park, California); Zahid Hussain (Orinda, California); Zhi-Xun Shen (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wanli Yang (El Cerrito, California); Jason D. Fabbri (San Francisco, California); Nicholas A. Melosh (Menlo Park, California); Zahid Hussain (Orinda, California); Zhi-Xun Shen (Stanford, California) |
| ABSTRACT | Provided are electron emitters based upon diamondoid monolayers, preferably self-assembled higher diamondoid monolayers. High intensity electron emission has been demonstrated employing such diamondoid monolayers, particularly when the monolayers are comprised of higher diamondoids. The application of such diamondoid monolayers can alter the band structure of substrates, as well as emit monochromatic electrons, and the high intensity electron emissions can also greatly improve the efficiency of field-effect electron emitters as applied to industrial and commercial applications. |
| FILED | Monday, April 09, 2012 |
| APPL NO | 13/442563 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570079 | Ferriss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark Ferriss (Tarrytown, New York); Alexander V. Rylyakov (Mount Kisco, New York); Jose A. Tierno (Stamford, Connecticut) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Mark Ferriss (Tarrytown, New York); Alexander V. Rylyakov (Mount Kisco, New York); Jose A. Tierno (Stamford, Connecticut) |
| ABSTRACT | There is provided a method for reducing lock time in a phase locked loop. The method includes detecting a saturation condition on a path within the phase locked loop. The method further includes temporarily applying saturation compensation along the path when the saturation condition is detected. |
| FILED | Wednesday, September 07, 2011 |
| APPL NO | 13/226557 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/156 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570227 | Mileski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul M. Mileski (Mystic, Connecticut) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul M. Mileski (Mystic, Connecticut) |
| ABSTRACT | A transmit antenna system includes active transmit electronics. A transistor has its gate coupled to a pulse generator for receiving the voltage pulses produced thereby. A coupled inductor is coupled to the transistor's drain. A tuning capacitor is coupled to the coupled inductor. An antenna is coupled to the coupled inductor and tuning capacitor. A choke inductor is coupled to the coupled inductor and a direct current voltage source. During each of the voltage pulses of the pulse generator, a resonant circuit is defined where parameters of the resonant circuit include resistance and capacitance of the antenna, capacitance of the tuning capacitor, inductance of the coupled inductor, and capacitance of the transistor. The resonant circuit is configured such that a resonant frequency thereof is equal to the pulse frequency of the pulse generator. |
| FILED | Thursday, September 15, 2011 |
| APPL NO | 13/233339 |
| ART UNIT | 2821 — Semiconductors/Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/722 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570656 | Weissman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Weissman (Brewster, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Weissman (Brewster, New York) |
| ABSTRACT | The embodiments herein describe how if a narrow wave length notch of light is used to illuminate or create an image source then the beam-splitter is only required to transmit over the narrow wavelength notch. If the concave mirror only reflects the same wavelength notch then all other wavelengths will pass through the mirror and be reflected by the beam-splitter. Each of the embodiments uses a method of optical design wherein certain portions or elements of the optical system are used for multiple purposes and/or transmit certain paths of light transmission in multiple directions. This use of multiple purposes and multiple paths produces embodiments of the invention that are smaller and more robust. |
| FILED | Sunday, April 04, 2010 |
| APPL NO | 12/753899 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/631 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570785 | Perner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederick Perner (Santa Barbara, California) |
| ASSIGNEE(S) | Hewlett-Packard Development Company (Houston, Texas) |
| INVENTOR(S) | Frederick Perner (Santa Barbara, California) |
| ABSTRACT | A method for reading a memory element within a crossbar array includes switching a column line connected to a target memory element of the crossbar array to connected to an input of a current mirror; applying an error voltage to unselected rows of the crossbar array; applying a sense voltage to a row line connected to the target memory element; and measuring an output current of the current mirror. |
| FILED | Wednesday, May 26, 2010 |
| APPL NO | 12/788161 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/148 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571080 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robin K. Huang (N. Billerica, Massachusetts); Reuel P. Swint (Billerica, Massachusetts); Joseph P. Donnelly (Carlisle, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robin K. Huang (N. Billerica, Massachusetts); Reuel P. Swint (Billerica, Massachusetts); Joseph P. Donnelly (Carlisle, Massachusetts) |
| ABSTRACT | A slab-coupled optical waveguide laser (SCOWL) is provided that includes an upper and lower waveguide region for guiding a laser mode. The upper waveguide region is positioned in the interior regions of the SCOWL. The lower waveguide region also guides the laser mode. The lower waveguide region is positioned in an area underneath the upper waveguide region. An active region is positioned between the upper waveguide region and the lower waveguide region. The active region is arranged so etching into the SCOWL is permitted to define one or more ridge structures leaving the active region unetched. |
| FILED | Wednesday, December 02, 2009 |
| APPL NO | 12/629572 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/45.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571154 | Lackey |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raymond J. Lackey (Bohemia, New York) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Raymond J. Lackey (Bohemia, New York) |
| ABSTRACT | An adaptive time delay control system is provided for matching the propagation time delay between two samples of a signal traveling through two independent paths so that they can be coherently combined for additional signal processing functions such as cosite interference cancellers, adaptive interference cancellers and adaptive beam formers. The adaptive time delay control system and associated method advantageously provide improved continuous matching of the two channels over a wider adjustment range while preserving both convergence speed over the full range and minimum jitter upon convergence by using composite autocorrelation functions to control (adjusting) a matching time delay in one channel. |
| FILED | Thursday, April 19, 2012 |
| APPL NO | 13/450999 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/347 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571214 | Lima et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Luisa Lima (Oporto, Portugal); Steluta Gheorghiu (Corbera de Llobregat, Spain); Joao Barros (Oporto, Portugal); Muriel Medard (Belmont, Massachusetts); Alberto Lopez Toledo (Brooklyn, New York); Joao Vilela (Coimbra, Portugal) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Luisa Lima (Oporto, Portugal); Steluta Gheorghiu (Corbera de Llobregat, Spain); Joao Barros (Oporto, Portugal); Muriel Medard (Belmont, Massachusetts); Alberto Lopez Toledo (Brooklyn, New York); Joao Vilela (Coimbra, Portugal) |
| ABSTRACT | Described herein is a method and system for hierarchical wireless video with network coding which limits encryption operations to a critical set of network coding coefficients in combination with multi-resolution video coding. Such a method and system achieves hierarchical fidelity levels, robustness against wireless packet loss and efficient security by exploiting the algebraic structure of network coding. |
| FILED | Friday, March 25, 2011 |
| APPL NO | 13/071674 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Cryptography 380/212 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571332 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Neeraj Kumar (New York, New York); Peter N Belhumeur (New York, New York); Shree K Nayar (New York, New York); Alexander C Berg (Stony Brook, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Neeraj Kumar (New York, New York); Peter N Belhumeur (New York, New York); Shree K Nayar (New York, New York); Alexander C Berg (Stony Brook, New York) |
| ABSTRACT | Methods, systems, and media for automatically classifying face images are provided. In some embodiments, features of the face image to be classified for an attribute are selected, wherein each of the features corresponds to a different region of the face image and specifies one or more of a type of pixel data to be evaluated for the region, a normalization to be applied for the region, and an aggregation to be applied for the region. The face image is classified with respect to the attribute based on the features of the image, and the attribute and a confidence value are assigned to the face image based on the classifying. A query is received from a user, and the attribute is identified as corresponding to the query. The face image is determined as corresponding to the attribute, and the face image is identified to the user as corresponding to the query. |
| FILED | Thursday, March 19, 2009 |
| APPL NO | 12/933639 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/224 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571362 | Dong |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Po Dong (Arcadia, California) |
| ASSIGNEE(S) | Mellanox Technologies Ltd. (Monterey Park, California) |
| INVENTOR(S) | Po Dong (Arcadia, California) |
| ABSTRACT | An optical device includes a first region interfaced with a second region. The first region includes one or more surfaces that are formed using electron-beam lithography and the second region includes one or more surfaces that are formed using photolithography. A component crosses the interface and includes a first portion located in the first region and a second portion located in the second region. The component includes a light-signal carrying region that constrains light signals. The first portion includes a first taper that expands the light-signal carrying region as the component approaches the interface and the second portion includes a second taper that expands the light-signal carrying region as the component approaches the interface. |
| FILED | Monday, March 30, 2009 |
| APPL NO | 12/384094 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/31 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571371 | Gibson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel J. Gibson (Cheverly, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Frederic H. Kung (Alexandria, Virginia); Pablo C Pureza (Burke, Virginia); Robert E Miklos (La Plata, Maryland); Guillermo R. Villalobos (Springfield, Virginia); Leslie Brandon Shaw (Woodbridge, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Daniel J. Gibson (Cheverly, Maryland); Jasbinder S. Sanghera (Ashburn, Virginia); Frederic H. Kung (Alexandria, Virginia); Pablo C Pureza (Burke, Virginia); Robert E Miklos (La Plata, Maryland); Guillermo R. Villalobos (Springfield, Virginia); Leslie Brandon Shaw (Woodbridge, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina) |
| ABSTRACT | A method and apparatus for making a substantially void-free preform for a microstructured optical fiber using a one-step process is provided. A preform is prepared from specialty glasses using a direct extrusion method. A die for use with the direct extrusion method is also provided, and a method for drawing the preform into a HC-PBG fiber for use in transmitting infra-red wavelength light is also provided. The preform comprises an outer jacket made of solid glass, a cladding having a plurality of air holes arranged in a desired pattern within the jacket, and a core which is hollow. |
| FILED | Wednesday, June 15, 2011 |
| APPL NO | 13/160760 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/125 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571373 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiaolong Wang (Austin, Texas); Ray T Chen (Austin, Texas); Harish Subbaraman (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaolong Wang (Austin, Texas); Ray T Chen (Austin, Texas); Harish Subbaraman (Austin, Texas) |
| ABSTRACT | An active device for dynamic control of lightwave transmission properties has at least one photonic crystal waveguide that has anti-reflection photonic crystal waveguides with gradually changed group refractive indices at both input and output side. An alternating voltage or current signal applied to two electrically conductive regions changes the refractive indices of the photonic crystal materials, introducing a certain degree of blue-shift or red-shift of the transmission spectrum of the photonic crystal waveguide. The output lightwave with frequency close to the band-edge of the photonic crystal waveguide is controlled by the input electric signal. Devices having one or more such active photonic crystal waveguides may be utilized as an electro-optic modulator, an optical switch, or a tunable optical filter. |
| FILED | Monday, May 23, 2011 |
| APPL NO | 13/068830 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/129 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571421 | Willis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John C. Willis (Rochester, Minnesota); Ruth A. Betcher (Rochester, Minnesota) |
| ASSIGNEE(S) | FTL Systems, Inc. (Rochester, Minnesota) |
| INVENTOR(S) | John C. Willis (Rochester, Minnesota); Ruth A. Betcher (Rochester, Minnesota) |
| ABSTRACT | An apparatus is disclosed for the optical generation of clock signals with tunable frequency and low jitter. A laser source serves as both the carrier used to transmit the clock signal for use by other optical, electronic or hybrid circuit elements and the original modulation time base. A fraction of the original laser source undergoes one or more stages of frequency division before being recombined as a modulation signal with the remaining laser beam. Transmission of the resulting signal via single mode fiber and dividers retains the low jitter properties of the modulated signal. By starting with a clock signal of optical frequency then dividing downward in frequency, comparatively high frequency clocks may be generated, notably in the GigaHertz and TeraHertz frequency ranges. |
| FILED | Monday, September 22, 2008 |
| APPL NO | 12/679259 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Optical communications 398/201 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571727 | Patera |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Russell Paul Patera (Torrance, California) |
| ABSTRACT | An improved method for launch vehicle guidance is disclosed. A pre-computed energy-angular momentum (E-J) curve to place a launch vehicle into a target orbit is received and stored. An energy, angular momentum, radial distance, velocity magnitude, and flight path angle of the launch vehicle are computed from state vector data while the launch vehicle is traveling to the target orbit. The pre-computed E-J curve and the computed energy, angular momentum, radial distance, velocity magnitude, and flight path angle of the launch vehicle are used to determine pitch and pitch rate of the launch vehicle. |
| FILED | Wednesday, February 06, 2013 |
| APPL NO | 13/760189 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572018 | Mishra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bhubaneswar Mishra (Great Neck, New York); Marco Antoniotti (Baldwin Place, New York); Naren Ramakrishnan (Blacksburg, Virginia) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Bhubaneswar Mishra (Great Neck, New York); Marco Antoniotti (Baldwin Place, New York); Naren Ramakrishnan (Blacksburg, Virginia) |
| ABSTRACT | A method, system and software arrangement in accordance with an exemplary embodiment of the present invention are provided to extract descriptive narrative from numerical experimental data augmented with ontological controlled vocabulary. One exemplary application of such system, method and software arrangement is in organizing gene-expression time course data in terms of biological processes that may be activated and deactivated as the biological system responds to its normal or perturbed environment. The present invention may also have biological applications to drug-or-vaccine discovery, understanding behavior of a cell in an altered diseased state (e.g., cancer, neuro-degeneration or auto-immune disease, etc.), genetically modifying a natural wild-type organism, genetic-engineering, etc. Other exemplary applications may include understanding neural behavior, market behavior of a population of users interacting on the Internet, etc. |
| FILED | Monday, June 21, 2010 |
| APPL NO | 12/803195 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/55 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572144 | Vigoda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Benjamin Vigoda (Winchester, Massachusetts); Jeffrey Bernstein (Middleton, Massachusetts); Alexander Alexeyev (Beverly, Massachusetts) |
| ASSIGNEE(S) | Analog Devices, Inc. (Norwood, Massachusetts) |
| INVENTOR(S) | Benjamin Vigoda (Winchester, Massachusetts); Jeffrey Bernstein (Middleton, Massachusetts); Alexander Alexeyev (Beverly, Massachusetts) |
| ABSTRACT | A circuit includes a signal processing circuit for accepting an input and for generating a set of outputs. The input is provided in an input range that has a set of representative values, and each output represents a measure of an association of the input with one or more of the representative values. The signal processing circuit includes a group of output sections, each output section being responsive to the input of the signal processing circuit. Each output section includes one or more sigmoid generators. Each sigmoid generator is responsive to an input of the output section to generate an output that represents a sigmoid function of the input of the output section. Each output section also includes a circuitry for combining the outputs of the one or more sigmoid generators to form one of the set of outputs of the signal processing circuit. An input transformation circuit is coupled to the plurality of output sections. The input transformation circuit is configurable to transform the input of the signal processing circuit for controlling a mapping characteristic from the input to the set of outputs. |
| FILED | Tuesday, March 02, 2010 |
| APPL NO | 12/716113 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/274 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572590 | Lethin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard A. Lethin (New York, New York); Allen K. Leung (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | Richard A. Lethin (New York, New York); Allen K. Leung (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York) |
| ABSTRACT | Methods, apparatus and computer software product for source code optimization are provided. In an exemplary embodiment, a first custom computing apparatus is used to optimize the execution of source code on a second computing apparatus. In this embodiment, the first custom computing apparatus contains a memory, a storage medium and at least one processor with at least one multi-stage execution unit. The second computing apparatus contains at least two multi-stage execution units that avow for parallel execution of tasks. The first custom computing apparatus optimizes the code for both parallelism and locality of operations on the second computing apparatus. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims. |
| FILED | Wednesday, September 16, 2009 |
| APPL NO | 12/561152 |
| ART UNIT | 2197 — Cryptography and Security |
| CURRENT CPC | Data processing: Software development, installation, and management 717/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572595 | Lethin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard A. Lethin (New York, New York); Allen K. Leung (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | Richard A. Lethin (New York, New York); Allen K. Leung (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York) |
| ABSTRACT | Computer-executed transformation of source code enables optimization of the code for one or more of parallelism, locality, and memory footprint of operations represented in the source code on a computing apparatus. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules that allow a reader to quickly ascertain the subject matter of the disclosure contained herein. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims. |
| FILED | Friday, August 05, 2011 |
| APPL NO | 13/204517 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/155 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572735 | Ghosh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anup K. Ghosh (Centreville, Virginia); Yih Huang (Fairfax, Virginia); Arun Sood (Clifton, Virginia) |
| ASSIGNEE(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Anup K. Ghosh (Centreville, Virginia); Yih Huang (Fairfax, Virginia); Arun Sood (Clifton, Virginia) |
| ABSTRACT | An attack resistant continuous network service trustworthiness controller comprising: state estimation module(s), response selection module(s), actuation module(s), and client dispatcher communication module(s) for maintaining the availability and integrity of online server(s). The state estimation module(s) are configured to generate state estimate(s) for online server(s) using behavior data obtained using sensor module(s). The response selection module(s) are configured to determine corrective action(s) to maintain the availability and integrity of online server(s) when state estimate(s) indicate that the integrity of an online server(s) is compromised. The actuation module(s) are configured to activate actuator(s) based upon the corrective action(s). Client dispatcher communication module(s) are configured to communicate online server availability information to a client dispatcher. |
| FILED | Monday, March 31, 2008 |
| APPL NO | 12/059454 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Information security 726/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 08568692 | Banaszak-Holl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark Banaszak-Holl (Ann Arbor, Michigan); Joseph Wallace (Indianapolis, Indiana); Blake Erickson (Ann Arbor, Michigan); Clifford M. Les (Birmingham, Michigan); Bradford G. Orr (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Mark Banaszak-Holl (Ann Arbor, Michigan); Joseph Wallace (Indianapolis, Indiana); Blake Erickson (Ann Arbor, Michigan); Clifford M. Les (Birmingham, Michigan); Bradford G. Orr (Ann Arbor, Michigan) |
| ABSTRACT | Methods and systems for diagnosing a bone disease related to collagen pathology in a subject are provided. These include providing a bone sample from the subject and determining a quantitative collagen morphology value of the bone sample. A reference value is provided from a non-affected control subject where the reference value is a quantitative collagen morphology value from the same type of bone sample obtained from a population of non-affected control subjects. The quantitative collagen morphology value of the subject's bone sample is compared to the reference value. If the collagen morphology value is altered versus the reference value, the subject is diagnosed as having a collagen related bone disease. The collagen morphology value can include mean fibril spacings and distributions of the fibril spacings taken from a subject's bone sample. |
| FILED | Friday, July 30, 2010 |
| APPL NO | 12/847408 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568694 | Kuppusamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Periannan Kuppusamy (New Albany, Ohio); Ramasamy P. Pandian (Columbus, Ohio); Narasimham L. Parinandi (Upper Arlington, Ohio); Jay L. Zweier (Blacklick, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Periannan Kuppusamy (New Albany, Ohio); Ramasamy P. Pandian (Columbus, Ohio); Narasimham L. Parinandi (Upper Arlington, Ohio); Jay L. Zweier (Blacklick, Ohio) |
| ABSTRACT | A new class of micro- and nano-particulate paramagnetic spin probes especially useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro. |
| FILED | Friday, January 15, 2010 |
| APPL NO | 12/688767 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568708 | Cheong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Ian Cheong (Singapore, Singapore); Shibin Zhou (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ABSTRACT | Clostridium novyi is an obligate anaerobe that can infect hypoxic regions within experimental tumors. We found that mice bearing large, established tumors were often cured when treated with C. novyi plus a single dose of liposomal doxorubicin. The secreted factor responsible for this phenomenon was identified and, surprisingly, proved to be a member of the lipase family. The gene encoding this protein, called liposomase, has the potential to be incorporated into diverse therapeutic methods to deliver specifically a variety of chemotherapeutic agents to tumors. |
| FILED | Monday, December 03, 2012 |
| APPL NO | 13/692064 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568716 | Franano |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | F. Nicholas Franano (Kansas City, Missouri) |
| ASSIGNEE(S) | Proteon Therapeutics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | F. Nicholas Franano (Kansas City, Missouri) |
| ABSTRACT | The invention provides methods for treating an obstructed biological conduit that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes prophylactically dilating a section of conduit to minimize the risk of obstruction formation. |
| FILED | Friday, June 16, 2006 |
| APPL NO | 11/454554 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.640 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568734 | Masignani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vega Masignani (Siena, Italy); Maria Scarselli (Sliena, Italy); Barbara Capecchi (Siena, Italy); Victoria Sharma (Orinda, California); Susan W Barnett (San Francisco, California); Indresh K. Srivastava (Benicia, California); Rino Rappuoli (Castelnuovo Berardenga, Italy) |
| ASSIGNEE(S) | Novartis Vaccines and Diagnostics Inc. (Emeryville, California) |
| INVENTOR(S) | Vega Masignani (Siena, Italy); Maria Scarselli (Sliena, Italy); Barbara Capecchi (Siena, Italy); Victoria Sharma (Orinda, California); Susan W Barnett (San Francisco, California); Indresh K. Srivastava (Benicia, California); Rino Rappuoli (Castelnuovo Berardenga, Italy) |
| ABSTRACT | Fusion proteins comprising CD4 minimal modules that bind to HIV Env polypeptides in a non-CD4 backbone are described. Also described are complexes of these fusion proteins with Env as well as methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided. |
| FILED | Wednesday, March 21, 2012 |
| APPL NO | 13/426295 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/192.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568737 | Gardella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas J. Gardella (Needham, Massachusetts); John T. Potts, Jr. (Newton, Massachusetts); Masaru Shimizu (Shizuoka, Japan); Fumihiko Ichikawa (Tokyo, Japan); Harald Juppner (Lexington, Massachusetts); Makoto Okazaki (Shizuoka, Japan) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Chugai Pharmaceutical Co., Ltd. (Tokyo, Japan) |
| INVENTOR(S) | Thomas J. Gardella (Needham, Massachusetts); John T. Potts, Jr. (Newton, Massachusetts); Masaru Shimizu (Shizuoka, Japan); Fumihiko Ichikawa (Tokyo, Japan); Harald Juppner (Lexington, Massachusetts); Makoto Okazaki (Shizuoka, Japan) |
| ABSTRACT | The present invention provides screening methods for GPCRs based on the discovery that the affinity of a receptor agonist for a GPCR (such as the parathyroid hormone receptor) when not bound to a G-protein is correlated with the length of time over which the agonist is effective, independently of its pharmacokinetic properties. The invention also provides PTH- and PTHrP-derived polypeptides. |
| FILED | Friday, August 01, 2008 |
| APPL NO | 12/671429 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/198.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568739 | Pletnev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander G. Pletnev (Gaithersburg, Maryland); Brian R. Murphy (Bethesda, Maryland); Amber R. Engel (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Alexander G. Pletnev (Gaithersburg, Maryland); Brian R. Murphy (Bethesda, Maryland); Amber R. Engel (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed herein are chimeric TBEV/DEN4 flaviviruses including a first nucleic acid molecule including a 5′ non-coding region (NCR) from a DEN4 virus, a nucleic acid encoding a C protein and non-structural proteins from a DEN4 virus, and a 3′ NCR from a DEN4 virus, wherein nonstructural protein NS4B includes a phenylalanine at amino acid position 112, nonstructural protein NS5 includes an alanine at amino acid position 654 and an alanine at amino acid position 655, and the 3′ NCR includes a deletion of nucleotides 10478-10507. The chimeric construct also includes a second nucleic acid molecule, which is operably linked to the first nucleic acid molecule, encoding a prM protein and an E protein from a TBEV, wherein the E protein includes an amino acid substitution that differs from the wild type TBEV at amino acid position 315 and a tryptophan at amino acid position 240. Also disclosed are methods of eliciting an immune response using the disclosed TBEV/DEN4 chimeric flaviviruses and immunogenic compositions including the disclosed chimeric flaviviruses and a pharmaceutically acceptable carrier. |
| FILED | Friday, May 28, 2010 |
| APPL NO | 13/322317 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/205.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568756 | Bassler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bonnie Bassler (Princeton, New Jersey); Lee Swem (San Carlos, California) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Bonnie Bassler (Princeton, New Jersey); Lee Swem (San Carlos, California) |
| ABSTRACT | Methods are provided for identifying molecules that can be used to positively and negatively manipulate quorum-sensing-mediated communication to control bacterial behavior. Small-molecule antagonists that disrupt quorum-sensing-mediated activities are identified. Methods are provided for disrupting detection of acyl-homoserine lactone autoinducer in Gram-negative bacteria by contacting the bacteria with the antagonists. Methods of inhibiting quorum sensing-mediated activity in Gram-negative bacteria are provided wherein the activity is pathogenicity, bioluminescence, siderophore production, type III secretion, or metalloprotease production. |
| FILED | Tuesday, June 02, 2009 |
| APPL NO | 12/995476 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/405 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568766 | Anantharamaiah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gattadahalli M. Anantharamaiah (Birmingham, Alabama); Alan M. Fogelman (Beverly Hills, California); Mohamad Navab (Los Angeles, California); Martin Rudolf (Lubeck, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gattadahalli M. Anantharamaiah (Birmingham, Alabama); Alan M. Fogelman (Beverly Hills, California); Mohamad Navab (Los Angeles, California); Martin Rudolf (Lubeck, Germany) |
| ABSTRACT | This invention provides novel active agents (e.g. peptides, small organic molecules, amino acid pairs, etc.) peptides that ameliorate one or more symptoms of eye disease and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The agents are highly stable and readily administered via an oral route or via intraocular injection. |
| FILED | Thursday, February 07, 2008 |
| APPL NO | 12/027728 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/429 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568769 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter X. Ma (Ann Arbor, Michigan); Guobao Wei (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Peter X. Ma (Ann Arbor, Michigan); Guobao Wei (Ann Arbor, Michigan) |
| ABSTRACT | Porous materials and methods for forming them are disclosed. One method for immobilizing micro-particles and/or nano-particles onto internal pore surfaces and/or external pore surfaces of porous materials includes suspending the micro-particles and/or nano-particles in a liquid adapted to swell, soften, and/or deform either the porous materials and/or the particles, thereby forming a liquid-particle suspension. The method further includes adding the suspension to the porous materials; and removing the liquid, thereby forming the porous materials having the micro-particles and/or nano-particles immobilized on the internal pore surfaces and/or the external pore surfaces. |
| FILED | Thursday, August 02, 2012 |
| APPL NO | 13/564874 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/443 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568786 | Simone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric Simone (Philadelphia, Pennsylvania); Vladimir R. Muzykantov (Warwick, Pennsylvania); Thomas D. Dziubla (Lexington, Kentucky) |
| ASSIGNEE(S) | The Trustees of the Universtiy of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Eric Simone (Philadelphia, Pennsylvania); Vladimir R. Muzykantov (Warwick, Pennsylvania); Thomas D. Dziubla (Lexington, Kentucky) |
| ABSTRACT | A method of controlling a physical characteristic of polymeric nanocarrier-encapsulated protein particles includes altering or selecting a weight percentage of a hydrophobic polymer block in a total amphiphilic diblock copolymer of a primary emulsion of a double emulsion, freeze-thaw technique. The primary emulsion is formed using a freeze-thaw cycle of the amphiphilic diblock copolymer and a protein having a molecular weight of up to or equal to 300,000 Da. Selection of the hydrophobic polymer block percentage alters one or more characteristics of the resulting nanoparticles, such as shape. Thus, as one aspect, a method of producing filamentous polymeric nanocarrier-encapsulated protein (i.e., active enzyme) particles involves forming a primary emulsion using a freeze-thaw cycle of (i) an amphiphilic diblock copolymer, which has a molecular weight of about 10,000 to about 100,000 Da and comprises a conjugate of the hydrophobic polymer block and a hydrophilic polymer block, wherein the amphiphilic diblock copolymer comprises greater than 81% to about 95% by weight of the hydrophobic polymer block; and a protein having a molecular weight of up to or equal to about 300,000 Da. Various compositions comprising such filamentous-shaped nanocarrier particles, and methods of use for diagnosis and therapy are disclosed. |
| FILED | Monday, October 27, 2008 |
| APPL NO | 12/739584 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/497 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568877 | Ferrari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugarland, Texas); Ciro Chiappini (Austin, Texas); Jean Raymond Fakhoury (Round Rock, Texas) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugarland, Texas); Ciro Chiappini (Austin, Texas); Jean Raymond Fakhoury (Round Rock, Texas) |
| ABSTRACT | Disclosed are a variety of porous and non-porous wire-like structures of microscopic and nanoscopic scale. For instance, disclosed are structures that comprise a porous object that comprises: (i) a first region; and (ii) a second region adjacent to the first region along an axis of the object, where the first region has at least one porous property different from that of the second region. Also disclosed are structures that include: (i) a high resistivity silicon; and (ii) a cross-section that is substantially perpendicular to an axis of the object. Also disclosed are methods of making and using such structures. For instance, the present invention provides methods of making a porous object by: (i) obtaining an etchable substrate; (ii) forming on a surface of the substrate a patterned porosification assisting metal layer that has at least one opening; and (iii) subsequently exposing the substrate to a first etching solution and a second etching solution to form respectively a first region and a second region of a porous object. |
| FILED | Wednesday, March 09, 2011 |
| APPL NO | 13/044250 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568878 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. Wilson (Campbell, California); Jung-Sub Wi (Tsukuba, Japan); Shan X. Wang (Portola Valley, California); Edward S. Barnard (Redwood City, California); Mark L. Brongersma (Menlo Park, California); Mary Tang (San Francisco, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Robert J. Wilson (Campbell, California); Jung-Sub Wi (Tsukuba, Japan); Shan X. Wang (Portola Valley, California); Edward S. Barnard (Redwood City, California); Mark L. Brongersma (Menlo Park, California); Mary Tang (San Francisco, California) |
| ABSTRACT | A Raman-active nanoparticle is provided that includes a dish-shape plasmonically active metal base, and a plasmonically active metal pillar disposed on the plasmonically active metal base, where the plasmonically active metal pillar is disposed within the dish-shape plasmonically active metal base and normal to a bottom of the dish-shape plasmonically active metal base, where a circular gap is disposed between the dish-shape plasmonically active metal pillar and inner walls of the dish-shape plasmonically active metal base. In one embodiment a Raman-active nanoparticle is provided that includes a dish-shape base having a dielectric material, an electrically conductive layer disposed on the inner surface of the dish-shape base, and an electrically conductive pillar disposed on the conductive layer, and within the dish-shape and perpendicular to a bottom of the dish-shape base, where a circular gap is disposed between the conductive pillar and inner walls of the dish-shape base. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/066248 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568968 | Lenz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Heinz-Josef Lenz (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Heinz-Josef Lenz (Los Angeles, California) |
| ABSTRACT | The invention provides compositions and methods for identifying a gender-specific cancer patient suitable for treatment with various treatment regimens available to cancer patients. After determining if a patient is suitable for therapy, the invention also provides methods for treating these patients. |
| FILED | Monday, April 12, 2010 |
| APPL NO | 12/758763 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568969 | Kahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Barbara B. Kahn (Cambridge, Massachusetts); Qin Yang (Brookline, Massachusetts); Tim Graham (Newton Center, Massachusetts); Odile Peroni (Brookline, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Barbara B. Kahn (Cambridge, Massachusetts); Qin Yang (Brookline, Massachusetts); Tim Graham (Newton Center, Massachusetts); Odile Peroni (Brookline, Massachusetts) |
| ABSTRACT | Methods for screening molecules that modulate the activity of Retinol Binding Protein 4 (RBP4) and their use in treatment of insulin resistance are described. Also described are methods of diagnosing insulin resistance and related conditions by detecting modulation of RBP4 activity. |
| FILED | Tuesday, May 22, 2012 |
| APPL NO | 13/477790 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568974 | Willman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cheryl L. Willman (Albuquerque, New Mexico); Richard Harvey (Placitas, New Mexico); George S. Davidson (Albuquerque, New Mexico); Xuefei Wang (Albuquerque, New Mexico); Susan R Atlas (Albuquerque, New Mexico); Edward J. Bedrick (Albuquerque, New Mexico); Iming L. Chen (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico); Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Cheryl L. Willman (Albuquerque, New Mexico); Richard Harvey (Placitas, New Mexico); George S. Davidson (Albuquerque, New Mexico); Xuefei Wang (Albuquerque, New Mexico); Susan R Atlas (Albuquerque, New Mexico); Edward J. Bedrick (Albuquerque, New Mexico); Iming L. Chen (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to the identification of genetic markers patients with high risk B-precursor acute lymphoblastic leukemia (B-ALL) and associated methods and their relationship to therapeutic outcome. The present invention also relates to diagnostic, prognostic and related methods using these genetic markers, as well as kits which provide microchips and/or immunoreagents for performing analysis on leukemia patients. |
| FILED | Friday, November 14, 2008 |
| APPL NO | 12/734542 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568977 | Takafuji et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vivian Takafuji (Springfield, Virginia); Xin Wei Wang (Rockville, Maryland); Paul K. Goldsmith (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Vivian Takafuji (Springfield, Virginia); Xin Wei Wang (Rockville, Maryland); Paul K. Goldsmith (Rockville, Maryland) |
| ABSTRACT | Based on the observation of the cooperation of osteopontin (OPN) and matrixmetalloproteinase-9 (MMP-9) in the promotion of the metastatic phenotype, therapies and diagnostic assays are disclosed for the treatment of a tumor that overexpresses OPN, such as hepatocellular carcinoma (HCC), for example metastatic HCC. In one example, methods of treating a tumor include administration of an agent that reduces cellular invasion resulting from the interaction between a fragment of OPN (OPN-5kD) generated by MMP-9 cleavage and CD44 receptor. Examples of such agents include fragments of OPN-5kD and antibodies specific for OPN-5kD. Therapeutic compositions are also provided that include such agents. Also provided are methods of diagnosing or prognosing a tumor, for example by detecting expression of OPN-5kD peptide or OPN-c mRNA in a biological sample obtained from the subject. Also provided are antibodies that specifically bind OPN-5kD. |
| FILED | Monday, July 16, 2012 |
| APPL NO | 13/549633 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568980 | Ozelius et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Laurie Ozelius (White Plains, New York); Susan Bressman (Englewood, New Jersey) |
| ASSIGNEE(S) | Mount Sinai School of Medicine (New York, New York); Beth Israel Medical Center (New York, New York) |
| INVENTOR(S) | Laurie Ozelius (White Plains, New York); Susan Bressman (Englewood, New Jersey) |
| ABSTRACT | The invention relates generally to the THAP1 gene and mutations in this gene, as well as the THAP1 protein and mutations in this protein, that are associated with dystonia. The invention relates to the identification, isolation, cloning and characterization of the DNA sequence corresponding to the wild type and mutant THAP1 genes, as well as isolation and characterization of their transcripts and gene products. The invention further relates to methods and kits useful for detecting mutations in THAP1 that are associated with dystonia, as well as to methods and kits useful for diagnosing dystonia. The present invention also relates to therapies for treating dystonia, including gene therapeutics and protein/antibody based therapeutics. |
| FILED | Wednesday, January 27, 2010 |
| APPL NO | 12/694908 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568981 | Lindstrom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen Lindstrom (Doraville, Georgia); Alexander Klimov (Atlanta, Georgia); Nancy Cox (Atlanta, Georgia); Lamorris Loftin (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Stephen Lindstrom (Doraville, Georgia); Alexander Klimov (Atlanta, Georgia); Nancy Cox (Atlanta, Georgia); Lamorris Loftin (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed. |
| FILED | Friday, July 20, 2012 |
| APPL NO | 13/554782 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568984 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ying-Hsiu Su (Audubon, Pennsylvania); Benjamin Song (Audubon, Pennsylvania); Janet Song (Audubon, Pennsylvania); Timothy M. Block (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | Philadelphia Health and Education Corporation (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ying-Hsiu Su (Audubon, Pennsylvania); Benjamin Song (Audubon, Pennsylvania); Janet Song (Audubon, Pennsylvania); Timothy M. Block (Doylestown, Pennsylvania) |
| ABSTRACT | Provided are methods of diagnosing and/or determining treatment of non-urinary tract cancers by detecting biomarkers, and aberrant methylation in said biomarkers, in human urine samples. |
| FILED | Friday, February 18, 2011 |
| APPL NO | 13/030888 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568990 | Zuker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles S. Zuker (San Diego, California); Jon Elliot Adler (Pacific Beach, California); Juergen Lindemeier (Werl, Germany) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Charles S. Zuker (San Diego, California); Jon Elliot Adler (Pacific Beach, California); Juergen Lindemeier (Werl, Germany) |
| ABSTRACT | The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors. |
| FILED | Friday, November 04, 2011 |
| APPL NO | 13/290026 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568995 | Lopes-Virella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Maria F. Lopes-Virella (Charleston, South Carolina); Gabriel T. Virella (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC Foundation for Research Development (Charleston, South Carolina); Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Maria F. Lopes-Virella (Charleston, South Carolina); Gabriel T. Virella (Charleston, South Carolina) |
| ABSTRACT | The present invention relates to the analysis of modified LDL in the context of immune complexes. In particular, ox-LDL and AGE-LDL are shown to predict the development of coronary artery disease and other micro- and macrovascular disorders, particularly in the context of diabetes. |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/885020 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568996 | Enghild et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jan Johannes Enghild (Aarhus, Denmark); Naftali Kaminski (Pittsburgh, Pennsylvania); Tim D. Oury (Wexford, Pennsylvania); Laura Voeghtly (Tarentum, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jan Johannes Enghild (Aarhus, Denmark); Naftali Kaminski (Pittsburgh, Pennsylvania); Tim D. Oury (Wexford, Pennsylvania); Laura Voeghtly (Tarentum, Pennsylvania) |
| ABSTRACT | A method is provided along with related reagent kits for aiding the diagnosis of IPF or other interstitial lung diseases, as well as for potential monitoring of disease progression or therapeutic response to treatment. |
| FILED | Friday, October 02, 2009 |
| APPL NO | 13/121142 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568998 | Mani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sendurai Mani (Cambridge, Massachusetts); Jing Yang (Cambridge, Massachusetts); Robert A. Weinberg (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Sendurai Mani (Cambridge, Massachusetts); Jing Yang (Cambridge, Massachusetts); Robert A. Weinberg (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating, diagnosing, and assisting in the diagnosis of metastasis in an individual, or of determining the metastatic potential of a tumor. The invention further relates to methods of identifying agents which inhibit metastasis. |
| FILED | Thursday, December 01, 2011 |
| APPL NO | 13/309067 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569002 | Lum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Lum (Dallas, Texas); Ozlem Kulak (Dallas, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Lawrence Lum (Dallas, Texas); Ozlem Kulak (Dallas, Texas) |
| ABSTRACT | Inhibitors of luciferase enzymes are disclosed and find use in multiplexed assays using multiple luciferases and multiple inhibitors, in both in vitro and in vivo embodiments. |
| FILED | Wednesday, October 20, 2010 |
| APPL NO | 12/908754 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569015 | Rasochova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lada L. Rasochova (Del Mar, California); Philip P. Dao (Lausanne, Switzerland); Jamie P. Phelps (Aurora, Colorado) |
| ASSIGNEE(S) | Pfenex Inc. (San Diego, California) |
| INVENTOR(S) | Lada L. Rasochova (Del Mar, California); Philip P. Dao (Lausanne, Switzerland); Jamie P. Phelps (Aurora, Colorado) |
| ABSTRACT | An optimized synthetic polynucleotide encoding a Bacillus anthracis protective antigen and an anthrax vaccine based on the encoded protective antigen. Furthermore, heterologous expression in a host Pseudomonas fluorescens bacteria of an optimized polynucleotide sequence encoding a Bacillus anthracis protective antigen. |
| FILED | Wednesday, May 30, 2007 |
| APPL NO | 11/809100 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569052 | Federspiel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William J. Federspiel (Pittsburgh, Pennsylvania); Brian J. Frankowski (Imperial, Pennsylvania); Tatsuro Yoshida (West Newton, Massachusetts); Paul J. Vernucci (Billerica, Massachusetts) |
| ASSIGNEE(S) | New Health Sciences, Inc. (Bethesda, Maryland); University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | William J. Federspiel (Pittsburgh, Pennsylvania); Brian J. Frankowski (Imperial, Pennsylvania); Tatsuro Yoshida (West Newton, Massachusetts); Paul J. Vernucci (Billerica, Massachusetts) |
| ABSTRACT | An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells. |
| FILED | Wednesday, May 25, 2011 |
| APPL NO | 13/115532 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569074 | Zand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Martin S. Zand (Rochester, New York); Alicia D. Henn (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Martin S. Zand (Rochester, New York); Alicia D. Henn (Rochester, New York) |
| ABSTRACT | A method of quantifying analyte secreted by a cell or released from a drug delivery vehicle, typically by ELISpot or fluorispot assay is described. Quantification is possible through the use of an analyte-releasing reagent that includes a bead and the analyte releasably bound to the bead, or a container pre-spotted with analyte released from the reagent. The reagent or pre-spotted containers can be used to provide a standard curve for release of the analyte. By detecting analyte secreted by one or more cells or drug released by a drug delivery vehicle, and comparing the detected analyte to the standard curve, it is possible to quantify the amount of analyte released by the one or more cells or drug released by the drug delivery vehicle. Kits and reagents for practicing the methods of the present invention are also disclosed. |
| FILED | Monday, April 30, 2007 |
| APPL NO | 12/298626 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569225 | Gilkeson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gary Gilkeson (Charleston, South Carolina); Stephen Tomlinson (Mount Pleasant, South Carolina); V. Michael Holers (Denver, Colorado); Baerbel Rohrer (Mount Pleasant, South Carolina) |
| ASSIGNEE(S) | MUSC Foundation for Research Development (Charleston, South Carolina); The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Gary Gilkeson (Charleston, South Carolina); Stephen Tomlinson (Mount Pleasant, South Carolina); V. Michael Holers (Denver, Colorado); Baerbel Rohrer (Mount Pleasant, South Carolina) |
| ABSTRACT | The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion. |
| FILED | Tuesday, May 18, 2010 |
| APPL NO | 12/782526 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569229 | Grunstein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael M. Grunstein (Merion Station, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michael M. Grunstein (Merion Station, Pennsylvania) |
| ABSTRACT | Compositions and methods for the treatment of asthma and inflammatory ocular disorders are disclosed. |
| FILED | Monday, August 09, 2010 |
| APPL NO | 12/852711 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569242 | Akassoglou |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Katerina Akassoglou (San Francisco, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Katerina Akassoglou (San Francisco, California) |
| ABSTRACT | The invention herein related to methods and compositions for treating nervous system disorders. The methods comprise administration of antibodies directed towards peptides that bind to receptors important in disease progression, thus attenuating the disease. |
| FILED | Tuesday, December 27, 2011 |
| APPL NO | 13/337504 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569245 | Luesch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hendrik Luesch (Gainesville, Florida); Valerie J. Paul (Fort Pierce, Florida); Jason C. Kwan (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Smithsonian Institution (Washington, District of Columbia) |
| INVENTOR(S) | Hendrik Luesch (Gainesville, Florida); Valerie J. Paul (Fort Pierce, Florida); Jason C. Kwan (Salt Lake City, Utah) |
| ABSTRACT | This invention relates to grassystatins A, B and C, and their isolated or purified forms. The compounds of the invention are useful as aspartic protease, gamma secretase, or metalloprotease inhibitors. Methods of using the compounds and compositions thereof are also disclosed. |
| FILED | Saturday, June 26, 2010 |
| APPL NO | 13/380775 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/20.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569276 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hyun K. Kim (Bellingham, Washington); Richard P. Blye (Highland, Maryland); Pemmaraju N. Rao (San Antonio, Texas); James W. Cessac (Floresville, Texas); Carmie K. Acosta (San Antonio, Texas) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Hyun K. Kim (Bellingham, Washington); Richard P. Blye (Highland, Maryland); Pemmaraju N. Rao (San Antonio, Texas); James W. Cessac (Floresville, Texas); Carmie K. Acosta (San Antonio, Texas) |
| ABSTRACT | The present invention relates, inter alia, to compounds having the general formula: in which R1, R2, R3, R4 and X are as defined by the present specification. In addition to providing the compounds of Formula I, the present invention provides methods wherein the compounds of Formula I are advantageously used, inter alia, to antagonize endogenous progesterone; to induce menses; to treat endometriosis; to treat dysmenorrhea; to treat endocrine hormone-dependent tumors; to treat meningiomas; to treat uterine leiomyomas; to treat uterine fibroids; to inhibit uterine endometrial proliferation; to induce cervical ripening; to induce labor; and for contraception. |
| FILED | Monday, February 28, 2005 |
| APPL NO | 11/069817 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/179 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569280 | von Andrian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ulrich H. von Andrian (Brookline, Massachusetts); Irina Mazo (Chestnut Hill, Massachusetts); Jean-Marc Gauguet (Jamaica Plain, Massachusetts) |
| ASSIGNEE(S) | Immune Disease Institute (Boston, Massachusetts) |
| INVENTOR(S) | Ulrich H. von Andrian (Brookline, Massachusetts); Irina Mazo (Chestnut Hill, Massachusetts); Jean-Marc Gauguet (Jamaica Plain, Massachusetts) |
| ABSTRACT | Methods for treating multiple myeloma with inhibitors of CXCR4, such as AMD3100 and anti-CXCR4 antibodies, are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma. |
| FILED | Wednesday, September 22, 2010 |
| APPL NO | 12/888001 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569308 | Conn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | P. Jeffrey Conn (Brentwood, Tennessee); Craig W. Lindsley (Brentwood, Tennessee); Kyle A. Emmitte (Spring Hill, Tennessee); Charles David Weaver (Franklin, Tennessee); Alice L. Rodriguez (Nashville, Tennessee); Andrew S. Felts (Nashville, Tennessee); Carrie K. Jones (Nashville, Tennessee); Brittney S. Bates (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | P. Jeffrey Conn (Brentwood, Tennessee); Craig W. Lindsley (Brentwood, Tennessee); Kyle A. Emmitte (Spring Hill, Tennessee); Charles David Weaver (Franklin, Tennessee); Alice L. Rodriguez (Nashville, Tennessee); Andrew S. Felts (Nashville, Tennessee); Carrie K. Jones (Nashville, Tennessee); Brittney S. Bates (Nashville, Tennessee) |
| ABSTRACT | Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/885245 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/255.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569321 | Ware et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Roy W. Ware (Raleigh, North Carolina); Merrick R. Almond (Apex, North Carolina); Bernhard M. Lampert (Rougemont, North Carolina) |
| ASSIGNEE(S) | Chimerix, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Roy W. Ware (Raleigh, North Carolina); Merrick R. Almond (Apex, North Carolina); Bernhard M. Lampert (Rougemont, North Carolina) |
| ABSTRACT | The disclosure describes methods of synthesis of phosphonate ester derivatives. Preferred methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of phosphonate ester derivatives without the use of chromatographic purification methods and in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of phosphonate ester derivatives. |
| FILED | Wednesday, August 31, 2011 |
| APPL NO | 13/223249 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/274 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569356 | Ostrov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David A. Ostrov (Gainesville, Florida); Brian K. Law (Gainesville, Florida); Patrick Corsino (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | David A. Ostrov (Gainesville, Florida); Brian K. Law (Gainesville, Florida); Patrick Corsino (Gainesville, Florida) |
| ABSTRACT | The invention relates to cyclin dependent kinase inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions for treating cell proliferative disorders, especially cancer. |
| FILED | Wednesday, October 25, 2006 |
| APPL NO | 12/084184 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/432 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569360 | Bottaro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donald P. Bottaro (Kensington, Maryland); Megan Peach (Ashburn, Virginia); Marc Nicklaus (Catonsville, Maryland); Nelly Tan (El Monte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald P. Bottaro (Kensington, Maryland); Megan Peach (Ashburn, Virginia); Marc Nicklaus (Catonsville, Maryland); Nelly Tan (El Monte, California) |
| ABSTRACT | Derivatives and analogs of inhibitors of receptor tyrosine kinase c-Met obtained by virtual screening, pharmaceutical compositions containing derivatives and analogs of c-Met inhibitors are provided. Methods of making derivatives and analogs of c-Met inhibitors and methods of use thereof are provided. Formula (I) |
| FILED | Tuesday, March 31, 2009 |
| APPL NO | 12/935646 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/454 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569377 | Simard |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | J. Marc Simard (Baltimore, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Department of Veteran Affairs (Washington, District of Columbia); University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | J. Marc Simard (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed to therapeutic compositions targeting the NCCa-ATP channel of an astrocyte, neuron or capillary endothelial cell and methods of using same. More specifically, antagonists of the NCCa-ATP channel are contemplated. The compositions are used to prevent cell death and to treat secondary damage associated with spinal cord injury. |
| FILED | Thursday, December 09, 2010 |
| APPL NO | 12/964018 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/592 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569450 | Pass et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kenneth A. Pass (Glenmont, New York); Barbara Lindau-Shepard (Albany, New York); David K. Janik (Deer Park, New York) |
| ASSIGNEE(S) | Health Research Inc. (Menands, New York) |
| INVENTOR(S) | Kenneth A. Pass (Glenmont, New York); Barbara Lindau-Shepard (Albany, New York); David K. Janik (Deer Park, New York) |
| ABSTRACT | The present invention relates to novel CD3 epsilon peptides, antibodies against the novel CD3 epsilon peptides. The invention also relates to methods of identifying an immunodeficiency (such as severe combined immunodeficiency (SCID) or a T cell immunodeficiency) in a patient, which may involve antibodies against CD3 epsilon peptides. |
| FILED | Thursday, March 03, 2011 |
| APPL NO | 13/039722 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569457 | Raines et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ronald T. Raines (Madison, Wisconsin); George N. Phillips, Jr. (Madison, Wisconsin); R. Jeremy Johnson (Middleton, Wisconsin); Jason G. McCoy (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); George N. Phillips, Jr. (Madison, Wisconsin); R. Jeremy Johnson (Middleton, Wisconsin); Jason G. McCoy (Madison, Wisconsin) |
| ABSTRACT | Cytotoxic variants of human ribonuclease 1 (RNase 1) identified through analysis of the interaction between RNase 1 and the human ribonuclease inhibitor (hRI) as defined by the three dimensional (3-D) atomic structure of the RNase1 hRI complex are disclosed. Also disclosed is the 3-D structure of the hRI·RNase 1 complex and methods for designing the RNase 1 variants. |
| FILED | Friday, September 14, 2012 |
| APPL NO | 13/619192 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569468 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fanqing Frank Chen (Moraga, California); Gang L. Liu (Berkeley, California); Luke P. Lee (Orinda, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Fanqing Frank Chen (Moraga, California); Gang L. Liu (Berkeley, California); Luke P. Lee (Orinda, California) |
| ABSTRACT | This invention provides a nanoplasmonic molecular ruler, which can perform label-free and real-time monitoring of nucleic acid (e.g., DNA) length changes and perform nucleic acid footprinting. In various embodiments the ruler comprises a nucleic acid attached to a nanoparticle, such that changes in the nucleic acid length are detectable using surface plasmon resonance. The nanoplasmonic ruler provides a fast and convenient platform for mapping nucleic acid-protein interactions, for nuclease activity monitoring, and for other footprinting related methods. |
| FILED | Friday, September 14, 2007 |
| APPL NO | 12/440579 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569471 | Phillips et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | M. Ian Phillips (Claremont, California); Yao Liang Tang (Claremont, California) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | M. Ian Phillips (Claremont, California); Yao Liang Tang (Claremont, California) |
| ABSTRACT | The invention relates to methods and compositions for selectively directing stem cells to a target tissue within a subject using a system that employs one or more vectors that contain a gene switch/biosensor, a tissue-specific promoter, a gene encoding a stem cell-attracting chemokine, and a gene amplification system. In one embodiment, a stem cell-attracting chemokine is expressed in damaged tissue using a stimulus-responsive vector system. The stimulus can be a physiological stimulus associated with cell injury, such as hypoxia or elevated glucose levels, for example. Expression of the chemokine increases the trafficking of stem cells to the damaged tissue. |
| FILED | Friday, November 18, 2011 |
| APPL NO | 13/299991 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569482 | Kuppusamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Periannan Kuppusamy (Columbus, Ohio); Vijay Kutala (Columbus, Ohio); Jay L. Zweier (Columbus, Ohio); Pawel Kwiatkowski (Dublin, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Periannan Kuppusamy (Columbus, Ohio); Vijay Kutala (Columbus, Ohio); Jay L. Zweier (Columbus, Ohio); Pawel Kwiatkowski (Dublin, Ohio) |
| ABSTRACT | A new class of micro- and nano-particulate paramagnetic spin probes useful for magnetic resonance imaging techniques, including electron paramagnetic resonance (EPR) and magnetic resonance imaging (MRI). The probes are lithium phthalocyanine derivative compounds. Also provided are suspensions and emulsions comprising lithium phthalocyanine derivative probes. Also provided are noninvasive methods for measuring noninvasive methods of measuring oxygen concentration, oxygen partial pressure, oxygen metabolism, and nitric oxide concentration in a specific tissue, organ, or cell in vivo or in vitro. |
| FILED | Tuesday, November 29, 2011 |
| APPL NO | 13/306565 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/139 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569536 | King |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | S. Bruce King (Walnut Cove, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | S. Bruce King (Walnut Cove, North Carolina) |
| ABSTRACT | Active compounds of Formula I are described: wherein: R1 and R2 are each independently C1-C4 alkyl; or R1 and R2 together form a C2-C7 alkylene chain; and Z is a non-steroidal anti-inflammatory drug (NSAID); along with pharmaceutically acceptable salts and prodrug thereof, and methods of using the same. |
| FILED | Monday, August 20, 2012 |
| APPL NO | 13/589422 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 560/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569542 | Serhan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles N. Serhan (Needham, Massachusetts); Bruce D. Levy (West Roxbury, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Charles N. Serhan (Needham, Massachusetts); Bruce D. Levy (West Roxbury, Massachusetts) |
| ABSTRACT | The present invention is generally drawn to novel isolated therapeutic agents, termed resolvins, generated from the interaction between a dietary omega-3 polyunsaturated fatty acid (PUFA) such as eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), cyclooxygenase-II (COX-2) and an analgesic, such as aspirin (ASA). Surprisingly, careful isolation of compounds generated from the combination of components in an appropriate environment provide di- and tri-hydroxy EPA or DHA compounds having unique structural and physiological properties. The present invention therefore provides for many new useful therapeutic di- or tri-hydroxy derivatives of EPA or DHA (resolvins) that diminish, prevent, or eliminate inflammation or PMN migration, for example. The present invention also provides methods of use, methods of preparation, and packaged pharmaceuticals for use as medicaments for the compounds disclosed throughout the specification. |
| FILED | Saturday, January 15, 2011 |
| APPL NO | 13/007600 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 562/598 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569573 | Grompe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Markus Grompe (Portland, Oregon); Hisaya Azuma (Tokyo, Japan); Muhsen Al-Dhalimy (Beaverton, Oregon); Mark A. Kay (Los Altos, California) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Markus Grompe (Portland, Oregon); Hisaya Azuma (Tokyo, Japan); Muhsen Al-Dhalimy (Beaverton, Oregon); Mark A. Kay (Los Altos, California) |
| ABSTRACT | Described herein is a method of expanding human hepatocytes in vivo using an immunodeficient mouse which is further deficient in fumarylacetoacetate hydrolase (Fah). The method comprises transplanting human hepatocytes into the immunodeficient and Fah-deficient mice, allowing the hepatocytes to expand and collecting the expanded human hepatocytes. The method also allows serial transplantation of the human hepatocytes into secondary, tertiary, quaternary or additional mice. Also provided are mutant mice comprising homozygous deletions or point mutations in the Fah, Rag2 and Il2rg genes. |
| FILED | Thursday, June 05, 2008 |
| APPL NO | 12/663219 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569680 | Luke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Geoffrey P. Luke (Austin, Texas); Cameron H. G. Wright (Laramie, Wyoming); Steven F. Barrett (Laramie, Wyoming) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Geoffrey P. Luke (Austin, Texas); Cameron H. G. Wright (Laramie, Wyoming); Steven F. Barrett (Laramie, Wyoming) |
| ABSTRACT | A multi-aperture passive light sensor and method for detecting motion and edges of an object are described. The sensor may include at least two focusing lenses mounted on a spherical surface for focusing light from the object into the ends of optical fibers, the optical axis for each lens diverging at an angle from that of adjacent lenses depending on the intended application. Each lens is located closer to the end of its associated optical fiber, which is disposed coaxially to the optical axis of the lens, than the natural focal plane of the lens, thereby blurring the light received from the object. Light exiting the fibers is detected by photosensors located at the opposite end of each optical fiber, and voltage differences between the voltages generated in response to the light intensity impinging on the photosensors are used to detect motion and edges of the object. |
| FILED | Tuesday, December 21, 2010 |
| APPL NO | 12/975139 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/221 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569695 | Zewail et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ahmed H. Zewail (Pasadena, California); David J. Flannigan (Temple City, California); Brett Barwick (Berlin, Connecticut) |
| ABSTRACT | A method of obtaining PINEM images includes providing femtosecond optical pulse, generating electron pulses, and directing the electron pulses towards a sample. The method also includes overlapping the femtosecond optical pulses and the electron pulses spatially and temporally at the sample and transferring energy from the femtosecond optical pulses to the electron pulses. The method further includes detecting electron pulses having an energy greater than a zero loss value, providing imaging in space and time. |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/863742 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570649 | Truong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thai V. Truong (Pasadena, California); John M. Choi (Tujunga, California); Scott E. Fraser (LaCanada, California); Willy Supatto (Paris, France); David S. Koos (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Thai V. Truong (Pasadena, California); John M. Choi (Tujunga, California); Scott E. Fraser (LaCanada, California); Willy Supatto (Paris, France); David S. Koos (Pasadena, California) |
| ABSTRACT | An apparatus for and method of performing light sheet microscopy (LISH) and light scanning microscopy (RAPS) in a single device are provided. The dual-mode imaging microscope allows for the use of both LISH and RAPS in a single instrument. This dual-mode device will allow researchers to have access to both types of microscopy, allowing access to the widest possible selection of samples. In addition, the device will reduce the high costs and space requirements associated with owning two different microscopes (LISH and RAPS). |
| FILED | Friday, October 29, 2010 |
| APPL NO | 12/916124 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/385 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571177 | Thorne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert E. Thorne (Ithaca, New York); Benjamin Apker (Barton, New York); Eric Hunt (Interlaken, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Robert E. Thorne (Ithaca, New York); Benjamin Apker (Barton, New York); Eric Hunt (Interlaken, New York) |
| ABSTRACT | A goniometer base for X-ray crystallography comprises a magnetic steel part with a cylindrical hole, a compliant cylindrical part that is inserted into this hole, and a cylindrical tube that is press-fit into the hole and holds the compliant part in place, such that when a crystal mounting tool is inserted through the concentric holes in each part, it is positively gripped and held in place at both T=300 K and T=100 K. |
| FILED | Tuesday, March 01, 2011 |
| APPL NO | 13/037715 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/73 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571278 | Sonka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Milan Sonka (Coralville, Iowa); Xiaodong Wu (Iowa City, Iowa); Yin Yin (Iowa City, Iowa); Xiangmin Zhang (Morgan Hill, California) |
| ASSIGNEE(S) | The University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Milan Sonka (Coralville, Iowa); Xiaodong Wu (Iowa City, Iowa); Yin Yin (Iowa City, Iowa); Xiangmin Zhang (Morgan Hill, California) |
| ABSTRACT | A system and methods for the efficient segmentation of globally optimal surfaces representing object boundaries in volumetric datasets is provided. An optical surface detection system and methods are provided that are capable of simultaneously detecting multiple interacting surfaces in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations. The present invention includes surface segmentation using a layered graph-theoretic approach that optimally segments multiple interacting surfaces of a single object using a pre-segmentation step, after which the segmentation of all desired surfaces of the object are performed simultaneously in a single optimization process. |
| FILED | Thursday, November 13, 2008 |
| APPL NO | 12/291803 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571293 | Ernst et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Queen's Medical Center (Honolulu, Hawaii); The University of Hawaii (Honolulu, Hawaii); The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | The Queen's Medical Center (Honolulu, Hawaii); The University of Hawaii (Honolulu, Hawaii); The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Thomas Michael Ernst (Honolulu, Hawaii); Thomas Edmund Prieto (Grafton, Wisconsin); Brian Stewart Randall Armstrong (Shorewood, Wisconsin) |
| ABSTRACT | This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time. |
| FILED | Monday, January 07, 2013 |
| APPL NO | 13/735907 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571668 | McClure et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kelly H. McClure (Simi Valley, California); Arup Roy (Valencia, California); Sumit Yadav (Los Angeles, California); Pishoy Maksy (Sherman Oaks, California); Peter Meilstrup (Seattle, Washington) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Kelly H. McClure (Simi Valley, California); Arup Roy (Valencia, California); Sumit Yadav (Los Angeles, California); Pishoy Maksy (Sherman Oaks, California); Peter Meilstrup (Seattle, Washington) |
| ABSTRACT | The present invention is a method of neural stimulation and more specifically an improved method of providing flexible video/image possessing in a visual prosthesis by providing downloadable video filters. In a visual prosthesis, the input video image will, for the foreseeable future, be higher resolution than the output stimulation of the retina, optic nerve or visual cortex. This is due to limits of electrode array technology and the rapid advancement of video camera technology. It is therefore, advantageous to apply video processing algorithms (filters) to help provide the most useful information to the lower resolution electrode array. Different filters are more effective in different environments and for different subjects. Furthermore, filters will continue to improve over time. Examples of situation dependent filters include reverse image, contrast increasing, edge detection, segmentation using chromatic information and motion detection. Filters loaded in the video processing unit may be selected dynamically to suit the situation or the user's preference. It is therefore advantageous to provide flexibility in applying filters. However, it is also important to maintain the security necessary for a medical device. The present invention provides for an external (not implanted) video processing unit with downloadable video filters. |
| FILED | Thursday, October 25, 2007 |
| APPL NO | 11/923813 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08571670 — Mimicking neural coding in retinal ganglion cells with short pulse electrical stimulation
| US 08571670 | Fried et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shelley Fried (Berkeley, California); Frank Werblin (Berkeley, California); Matthew J. McMahon (Los Angeles, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Shelley Fried (Berkeley, California); Frank Werblin (Berkeley, California); Matthew J. McMahon (Los Angeles, California) |
| ABSTRACT | A method, device and system for stimulating visual tissue, typically in the retina or visual cortex, to achieve an artificial percept of light or image. The method includes providing stimulating electrodes suitable for placement in proximity to the visual tissue and generating a series of short-duration stimulation signals having a duration of less than about 0.5 milliseconds each. The short-duration stimulation signals are applied through the stimulating electrodes with varying frequencies that are substantially matched to a spiking range of frequencies of at least one ganglion cell for perceiving brightness or image. |
| FILED | Thursday, June 28, 2012 |
| APPL NO | 13/536817 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571671 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Samip Shah (Lake Forest, California); Amy Chu Peishuan Hines (Monterey Park, California); Dao Min Zhou (Saugus, California); Robert J. Greenberg (Los Angeles, California); Mark S. Humayun (Glendale, California); James D. Weiland (Valencia, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Samip Shah (Lake Forest, California); Amy Chu Peishuan Hines (Monterey Park, California); Dao Min Zhou (Saugus, California); Robert J. Greenberg (Los Angeles, California); Mark S. Humayun (Glendale, California); James D. Weiland (Valencia, California) |
| ABSTRACT | A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance. |
| FILED | Monday, July 02, 2012 |
| APPL NO | 13/540137 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571672 | Ok et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Second Sight Medical Products, Inc. (San Fernando, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Jerry Ok (Canyon Country, California); Robert J Greenberg (Los Angeles, California); Neil Hamilton Talbot (La Cresenta, California); James S Little (Newhall, California); Rongqing Dai (Valencia, California); Jordan Matthew Neysmith (Pasadena, California); Kelly H McClure (Simi Valley, California) |
| ABSTRACT | An implantable device including a first electrically non-conductive substrate with a plurality of electrically conductive vias. The device also includes a flip-chip multiplexer circuit attached to the first substrate using conductive bumps, the circuit being electrically connected to at least a subset of the of the electrically conductive vias. Another flip-chip driver circuit is attached to the flip-chip multiplexer circuit using conductive bumps while a second electrically non-conductive substrate is attached to the flip-chip driver circuit, also using conductive bumps. Discrete passives are attached to the second electrically non-conductive substrate and a cover is bonded to the first substrate. The cover, the first substrate, and the electrically conductive vias form a hermetic package. |
| FILED | Friday, March 01, 2013 |
| APPL NO | 13/783225 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08567223 | Golovashchenko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sergey Fedorovich Golovashchenko (Beverly Hills, Michigan); John Joseph Francis Bonnen (Milford, Michigan) |
| ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| INVENTOR(S) | Sergey Fedorovich Golovashchenko (Beverly Hills, Michigan); John Joseph Francis Bonnen (Milford, Michigan) |
| ABSTRACT | An electro-hydraulic forming tool having one or more electrodes for forming parts with sharp corners. The electrodes may be moved and sequentially discharged several times to form various areas of the tube. Alternatively, a plurality of electrodes may be provided that are provided within an insulating tube that defines a charge area opening. The insulating tube is moved to locate the charge area opening adjacent one of the electrodes to form spaced locations on a preform. In other embodiments, a filament wire is provided in a cartridge or supported by an insulative support. |
| FILED | Monday, September 21, 2009 |
| APPL NO | 12/563191 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal deforming 072/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567249 | Grossman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffrey C. Grossman (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey C. Grossman (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | An embodiment of a nanomechanical frequency detector includes a support structure and a plurality of elongated nanostructures coupled to the support structure. Each of the elongated nanostructures has a particular resonant frequency. The plurality of elongated nanostructures has a range of resonant frequencies. An embodiment of a method of identifying an object includes introducing the object to the nanomechanical resonance detector. A resonant response by at least one of the elongated nanostructures of the nanomechanical resonance detector indicates a vibrational mode of the object. An embodiment of a method of identifying a molecular species of the present invention includes introducing the molecular species to the nanomechanical resonance detector. A resonant response by at least one of the elongated nanostructures of the nanomechanical resonance detector indicates a vibrational mode of the molecular species. |
| FILED | Tuesday, August 18, 2009 |
| APPL NO | 12/543359 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/579 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08567355 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul Sai Keat Wang (Peoria Heights, Illinois); Darryl Baldwin (Lafayette, Indiana); Myoungjin Kim (Peoria, Illinois) |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Paul Sai Keat Wang (Peoria Heights, Illinois); Darryl Baldwin (Lafayette, Indiana); Myoungjin Kim (Peoria, Illinois) |
| ABSTRACT | An integrated control system for use with an engine connected to a generator providing electrical power to a switchgear is disclosed. The engine receives gas produced by a gasifier. The control system includes an electronic controller associated with the gasifier, engine, generator, and switchgear. A gas flow sensor monitors a gas flow from the gasifier to the engine through an engine gas control valve and provides a gas flow signal to the electronic controller. A gas oversupply sensor monitors a gas oversupply from the gasifier and provides an oversupply signal indicative of gas not provided to the engine. A power output sensor monitors a power output of the switchgear and provide a power output signal. The electronic controller changes gas production of the gasifier and the power output rating of the switchgear based on the gas flow signal, the oversupply signal, and the power output signal. |
| FILED | Wednesday, December 22, 2010 |
| APPL NO | 12/976811 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Internal-combustion engines 123/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568027 | Ivanov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ilia N. Ivanov (Knoxville, Tennessee); David Bruce Geohegan (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ilia N. Ivanov (Knoxville, Tennessee); David Bruce Geohegan (Knoxville, Tennessee) |
| ABSTRACT | The present invention, in one embodiment, provides a method of measuring pressure or temperature using a sensor including a sensor element composed of a plurality of carbon nanotubes. In one example, the resistance of the plurality of carbon nanotubes is measured in response to the application of temperature or pressure. The changes in resistance are then recorded and correlated to temperature or pressure. In one embodiment, the present invention provides for independent measurement of pressure or temperature using the sensors disclosed herein. |
| FILED | Wednesday, August 26, 2009 |
| APPL NO | 12/547562 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Thermal measuring and testing 374/185 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568318 | Huang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lianjie Huang (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Lianjie Huang (Los Alamos, New Mexico) |
| ABSTRACT | Methods for enhancing ultrasonic reflection imaging are taught utilizing a split-step Fourier propagator in which the reconstruction is based on recursive inward continuation of ultrasonic wavefields in the frequency-space and frequency-wave number domains. The inward continuation within each extrapolation interval consists of two steps. In the first step, a phase-shift term is applied to the data in the frequency-wave number domain for propagation in a reference medium. The second step consists of applying another phase-shift term to data in the frequency-space domain to approximately compensate for ultrasonic scattering effects of heterogeneities within the tissue being imaged (e.g., breast tissue). Results from various data input to the method indicate significant improvements are provided in both image quality and resolution. |
| FILED | Tuesday, February 19, 2008 |
| APPL NO | 12/033841 |
| ART UNIT | 3737 — Amusement and Education Devices |
| CURRENT CPC | Surgery 6/437 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568508 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Haorong Wang (Foster City, California); Yujiang Song (Albuquerque, New Mexico); John A. Shelnutt (Tijeras, New Mexico); Craig J. Medforth (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Haorong Wang (Foster City, California); Yujiang Song (Albuquerque, New Mexico); John A. Shelnutt (Tijeras, New Mexico); Craig J. Medforth (Albuquerque, New Mexico) |
| ABSTRACT | Metal nanostructures formed by photocatalytic interfacial synthesis using a porphyrin-stabilized emulsion template and the method for making the nanostructures. Catalyst-seeded emulsion droplets are employed as templates for hollow-nanoshell growth. The hollow metal nanospheres may be formed with or without inclusions of other materials. |
| FILED | Tuesday, October 05, 2010 |
| APPL NO | 12/897835 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568572 | Anders et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andre Anders (El Cerrito, California); Joakim Andersson (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andre Anders (El Cerrito, California); Joakim Andersson (Berkeley, California) |
| ABSTRACT | A method and apparatus are described for very low pressure high powered magnetron sputtering of a coating onto a substrate. By the method of this invention, both substrate and coating target material are placed into an evacuable chamber, and the chamber pumped to vacuum. Thereafter a series of high impulse voltage pulses are applied to the target. Nearly simultaneously with each pulse, in one embodiment, a small cathodic arc source of the same material as the target is pulsed, triggering a plasma plume proximate to the surface of the target to thereby initiate the magnetron sputtering process. In another embodiment the plasma plume is generated using a pulsed laser aimed to strike an ablation target material positioned near the magnetron target surface. |
| FILED | Thursday, June 10, 2010 |
| APPL NO | 12/797829 |
| ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/192.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568582 | Glatzmaier |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gregory C. Glatzmaier (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Gregory C. Glatzmaier (Golden, Colorado) |
| ABSTRACT | Systems and methods for selectively removing hydrogen gas from a hydrogen-containing fluid volume are disclosed. An exemplary system includes a proton exchange membrane (PEM) selectively permeable to hydrogen by exclusively conducting hydrogen ions. The system also includes metal deposited as layers onto opposite sides or faces of the PEM to form a membrane-electrode assembly (MEA), each layer functioning as an electrode so that the MEA functions as an electrochemical cell in which the ionic conductors are hydrogen ions, and the MEA functioning as a hydrogen selective membrane (HSM) when located at the boundary between a hydrogen-containing fluid volume and a second fluid. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 13/262220 |
| ART UNIT | 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/637 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568686 | Morse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Daniel E. Morse (Santa Barbara, California); Birgit Schwenzer (Goleta, California); John R. Gomm (Santa Barbara, California); Kristian M. Roth (Bothell, Washington); Brandon Heiken (Goleta, California); Richard Brutchey (Santa Barbara, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel E. Morse (Santa Barbara, California); Birgit Schwenzer (Goleta, California); John R. Gomm (Santa Barbara, California); Kristian M. Roth (Bothell, Washington); Brandon Heiken (Goleta, California); Richard Brutchey (Santa Barbara, California) |
| ABSTRACT | A method for the fabrication of nanostructured semiconducting, photoconductive, photovoltaic, optoelectronic and electrical battery thin films and materials at low temperature, with no molecular template and no organic contaminants. High-quality metal oxide semiconductor, photovoltaic and optoelectronic materials can be fabricated with nanometer-scale dimensions and high dopant densities through the use of low-temperature biologically inspired synthesis routes, without the use of any biological or biochemical templates. |
| FILED | Wednesday, April 18, 2007 |
| APPL NO | 11/737087 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/592.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568690 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yi Lu (Champaign, Illinois); Mehmet Veysel Yigit (Malden, Massachusetts); Debapriya Mazumdar (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Yi Lu (Champaign, Illinois); Mehmet Veysel Yigit (Malden, Massachusetts); Debapriya Mazumdar (Urbana, Illinois) |
| ABSTRACT | The present invention provides an MRI contrast agent, comprising: MRI contrast agent particles, and oligonucleotides, attached to the particles. |
| FILED | Tuesday, July 29, 2008 |
| APPL NO | 12/182018 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568828 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiaonan Li (Evergreen, Colorado); Timothy A. Gessert (Conifer, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Xiaonan Li (Evergreen, Colorado); Timothy A. Gessert (Conifer, Colorado) |
| ABSTRACT | A tin-cadmium oxide film having an amorphous structure and a ratio of tin atoms to cadmium atoms of between 1:1 and 3:1. The tin-cadmium oxide film may have an optical band gap of between 2.7 eV and 3.35 eV. The film may also have a charge carrier concentration of between 1×1020 cm−3 and 2×1020 cm−3. The tin cadmium oxide film may also exhibit a Hall mobility of between 40 cm2V−1 s−1 and 60 cm2V−1 s−1. Also disclosed is a method of producing an amorphous tin-cadmium oxide film as described and devices using same. |
| FILED | Friday, February 12, 2010 |
| APPL NO | 12/705465 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/255.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568914 | Pol et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vilas G. Pol (Willowbrook, Illinois); Swati V. Pol (Willowbrook, Illinois); Michael M. Thackeray (Naperville, Illinois) |
| ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Vilas G. Pol (Willowbrook, Illinois); Swati V. Pol (Willowbrook, Illinois); Michael M. Thackeray (Naperville, Illinois) |
| ABSTRACT | A lithium- or lithium-ion electrochemical cell of the present invention comprises a lithium-containing cathode, an anode, and a non-aqueous lithium-containing electrolyte therebetween; wherein one or more of the anode and the cathode comprises at least one particulate carbon-containing material selected from the group consisting of one or more carbon-coated metal oxide or metal phosphate particles, carbon-containing metals that alloy with Li, carbon-containing metalloids that alloy with Li, or rounded carbon particles such as carbon spheres, prolate-shaped spheroids, oblate-shaped spheroids, and carbon nanotubes. In a preferred embodiment, the particulate carbon material is prepared by reacting one or more solid, solvent-free chemical precursor materials comprising the elements making up the material in an enclosed autogenic pressure reactor in which the precursor materials are dissociated and reacted at elevated temperature, thereby creating self-generated pressure within the reactor. |
| FILED | Friday, October 29, 2010 |
| APPL NO | 12/915395 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/156 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569023 | Katz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a polyketide synthase (PKS) capable of synthesizing a dicarboxylic acid (diacid). Such diacids include diketide-diacids and triketide-diacids. The invention includes recombinant nucleic acid encoding the PKS, and host cells comprising the PKS. The invention also includes methods for producing the diacids. |
| FILED | Monday, March 30, 2009 |
| APPL NO | 12/922204 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/142 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569030 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brady D. Lee (Idaho Falls, Idaho); Deborah T. Newby (Idaho Falls, Idaho); Jeffrey A. Lacey (Idaho Falls, Idaho); David N. Thompson (Idaho Falls, Idaho); Vicki S. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Francisco F. Roberto (Idaho Falls, Idaho); David W. Reed (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Brady D. Lee (Idaho Falls, Idaho); Deborah T. Newby (Idaho Falls, Idaho); Jeffrey A. Lacey (Idaho Falls, Idaho); David N. Thompson (Idaho Falls, Idaho); Vicki S. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Francisco F. Roberto (Idaho Falls, Idaho); David W. Reed (Idaho Falls, Idaho) |
| ABSTRACT | Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering recombination inside or outside of a cell using isolated and/or purified polypeptides and/or nucleic acid sequences from Alicyclobacillus acidocaldarius. |
| FILED | Thursday, September 06, 2012 |
| APPL NO | 13/604979 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569031 | Novick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Codexis, Inc. (Redwood City, California) |
| ASSIGNEE(S) | Codexis, Inc. (Redwood City, California) |
| INVENTOR(S) | Scott J. Novick (Palo Alto, California); Oscar Alvizo (Fremont, California) |
| ABSTRACT | The present disclosure relates to chemically modified carbonic anhydrase polypeptides and soluble compositions, homogenous liquid formulations comprising them. The chemically modified carbonic anhydrase polypeptides have improved properties relative to the same carbonic anhydrase polypeptide that is not chemically modified including the improved properties of increased activity and/or stability in the presence of amine compounds, ammonia, or carbonate ion. The present disclosure also provides methods of preparing the chemically modified polypeptides and methods of using the chemically modified polypeptides for accelerating the absorption of carbon dioxide from a gas stream into a solution as well as for the release of the absorbed carbon dioxide for further treatment and/or sequestering. |
| FILED | Thursday, December 20, 2012 |
| APPL NO | 13/721648 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/188 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569041 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George M. Church (Brookline, Massachusetts); Harris H. Wang (Cambridge, Massachusetts); Farren J. Isaacs (Brookline, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Harris H. Wang (Cambridge, Massachusetts); Farren J. Isaacs (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to automated methods of introducing multiple nucleic acid sequences into one or more target cells. |
| FILED | Monday, March 05, 2012 |
| APPL NO | 13/411712 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/285.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569391 | Warren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott Warren (Washington, District of Columbia); Ulrich Wiesner (Ithaca, New York); Francis J. DiSalvo, Jr. (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Scott Warren (Washington, District of Columbia); Ulrich Wiesner (Ithaca, New York); Francis J. DiSalvo, Jr. (Ithaca, New York) |
| ABSTRACT | The invention provides mesostructured materials and methods of preparing mesostructured materials including metal-rich mesostructured nanoparticle-block copolymer hybrids, porous metal-nonmetal nanocomposite mesostructures, and ordered metal mesostructures with uniform pores. The nanoparticles can be metal, metal alloy, metal mixture, intermetallic, metal-carbon, metal-ceramic, semiconductor-carbon, semiconductor-ceramic, insulator-carbon or insulator-ceramic nanoparticles, or combinations thereof. A block copolymer/ligand-stabilized nanoparticle solution is cast, resulting in the formation of a metal-rich (or semiconductor-rich or insulator-rich) mesostructured nanoparticle-block copolymer hybrid. The hybrid is heated to an elevated temperature, resulting in the formation of an ordered porous nanocomposite mesostructure. A nonmetal component (e.g., carbon or ceramic) is then removed to produce an ordered mesostructure with ordered and large uniform pores. |
| FILED | Tuesday, January 13, 2009 |
| APPL NO | 12/812714 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/153 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569458 | Caimi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | E I du Pont de Nemours and Company (Wilmington, Delaware); Eileen Stieglitz (Wynnewood, Pennsylvania) |
| ASSIGNEE(S) | E I du Pont de Nemours and Company (Wilmington, Delaware) |
| INVENTOR(S) | Perry G. Caimi (Kennett Square, Pennsylvania); William D Hitz (Wilmington, Delaware); Paul V Viitanen (West Chester, Pennsylvania); Barry Stieglitz (Wynnewood, Pennsylvania) |
| ABSTRACT | Xylose-utilizing, ethanol producing strains of Zymomonas mobilis with improved performance in medium comprising biomass hydrolysate were isolated using an adaptation process. Independently isolated strains were found to have independent mutations in the same coding region. Mutation in this coding may be engineered to confer the improved phenotype. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/795148 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569468 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fanqing Frank Chen (Moraga, California); Gang L. Liu (Berkeley, California); Luke P. Lee (Orinda, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Fanqing Frank Chen (Moraga, California); Gang L. Liu (Berkeley, California); Luke P. Lee (Orinda, California) |
| ABSTRACT | This invention provides a nanoplasmonic molecular ruler, which can perform label-free and real-time monitoring of nucleic acid (e.g., DNA) length changes and perform nucleic acid footprinting. In various embodiments the ruler comprises a nucleic acid attached to a nanoparticle, such that changes in the nucleic acid length are detectable using surface plasmon resonance. The nanoplasmonic ruler provides a fast and convenient platform for mapping nucleic acid-protein interactions, for nuclease activity monitoring, and for other footprinting related methods. |
| FILED | Friday, September 14, 2007 |
| APPL NO | 12/440579 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569581 | Maiyuran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Suchindra Maiyuran (Gold River, California); Randall Kramer (Lincoln, California); Paul Harris (Carnation, Washington) |
| ASSIGNEE(S) | Novozymes, Inc (Davis, California) |
| INVENTOR(S) | Suchindra Maiyuran (Gold River, California); Randall Kramer (Lincoln, California); Paul Harris (Carnation, Washington) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Thursday, September 16, 2010 |
| APPL NO | 12/883549 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/284 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569677 | Gessner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oliver Gessner (Albany, California); Oleg A. Kornilov (Berlin, Germany); Russell B. Wilcox (El Cerrito, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Oliver Gessner (Albany, California); Oleg A. Kornilov (Berlin, Germany); Russell B. Wilcox (El Cerrito, California) |
| ABSTRACT | The invention provides for a device comprising an apparatus comprising (a) a transmission grating capable of diffracting a photon beam into a diffracted photon output, and (b) an image detector capable of detecting the diffracted photon output. The device is useful for measuring the spatial profile and diffraction pattern of a photon beam, such as a vacuum ultraviolet (VUV) beam. |
| FILED | Monday, July 26, 2010 |
| APPL NO | 12/843773 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569678 | Goldberg |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth A. Goldberg (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth A. Goldberg (Berkeley, California) |
| ABSTRACT | A novel micron-scale lens, a microlens, is engineered to concentrate light efficiently onto an area of interest, such as a small, light-sensitive detector element in an integrated electronic device. Existing microlens designs imitate the form of large-scale lenses and are less effective at small sizes. The microlenses described herein have been designed to accommodate diffraction effects, which dominate the behavior of light at small length scales. Thus a new class of light-concentrating optical elements with much higher relative performance has been created. Furthermore, the new designs are much easier to fabricate than previous designs. |
| FILED | Wednesday, March 04, 2009 |
| APPL NO | 12/921126 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/216 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569701 | Reda |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ibrahim Reda (Aurora, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Ibrahim Reda (Aurora, Colorado) |
| ABSTRACT | Implementations of the present disclosure involve an apparatus and method to measure the long-wave irradiance of the atmosphere or long-wave source. The apparatus may involve a thermopile, a concentrator and temperature controller. The incoming long-wave irradiance may be reflected from the concentrator to a thermopile receiver located at the bottom of the concentrator to receive the reflected long-wave irradiance. In addition, the thermopile may be thermally connected to a temperature controller to control the device temperature. Through use of the apparatus, the long-wave irradiance of the atmosphere may be calculated from several measurements provided by the apparatus. In addition, the apparatus may provide an international standard of pyrgeometers' calibration that is traceable back to the International System of Units (SI) rather than to a blackbody atmospheric simulator. |
| FILED | Wednesday, March 16, 2011 |
| APPL NO | 13/049275 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/353 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569708 | Stradins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pauls Stradins (Golden, Colorado); Howard M. Branz (Boulder, Colorado); Qi Wang (Littleton, Colorado); Harold R. McHugh (Santa Ynez, California) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Pauls Stradins (Golden, Colorado); Howard M. Branz (Boulder, Colorado); Qi Wang (Littleton, Colorado); Harold R. McHugh (Santa Ynez, California) |
| ABSTRACT | An apparatus (200) for detecting slow or thermal neutrons (160) including an alpha particle-detecting layer (240) that is a hydrogenated amorphous silicon p-i-n diode structure. The apparatus includes a bottom metal contact (220) and a top metal contact (250) with the diode structure (240) positioned between the two contacts (220, 250) to facilitate detection of alpha particles (170). The apparatus (200) includes a neutron conversion layer (230) formed of a material containing boron-10 isotopes. The top contact (250) is pixilated with each contact pixel extending to or proximate to an edge of the apparatus to facilitate electrical contacting. The contact pixels have elongated bodies to allow them to extend across the apparatus surface (242) with each pixel having a small surface area to match capacitance based upon a current spike detecting circuit or amplifier connected to each pixel. The neutron conversion layer (860) may be deposited on the contact pixels (830) such as with use of inkjet printing of nanoparticle ink. |
| FILED | Friday, January 30, 2009 |
| APPL NO | 13/146780 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/370.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569848 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chih-Wei Chang (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chih-Wei Chang (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | Disclosed are methods and devices in which certain types of nanotubes (e.g., carbon nanotubes and boron nitride nanotubes conduct heat with high efficiency and are therefore useful in electronic-type devices. |
| FILED | Monday, July 20, 2009 |
| APPL NO | 12/505586 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/414 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569941 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wanli Yang (El Cerrito, California); Jason D. Fabbri (San Francisco, California); Nicholas A. Melosh (Menlo Park, California); Zahid Hussain (Orinda, California); Zhi-Xun Shen (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wanli Yang (El Cerrito, California); Jason D. Fabbri (San Francisco, California); Nicholas A. Melosh (Menlo Park, California); Zahid Hussain (Orinda, California); Zhi-Xun Shen (Stanford, California) |
| ABSTRACT | Provided are electron emitters based upon diamondoid monolayers, preferably self-assembled higher diamondoid monolayers. High intensity electron emission has been demonstrated employing such diamondoid monolayers, particularly when the monolayers are comprised of higher diamondoids. The application of such diamondoid monolayers can alter the band structure of substrates, as well as emit monochromatic electrons, and the high intensity electron emissions can also greatly improve the efficiency of field-effect electron emitters as applied to industrial and commercial applications. |
| FILED | Monday, April 09, 2012 |
| APPL NO | 13/442563 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570035 | Wemmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Wemmer (Berkeley, California); Alexander Pines (Berkeley, California); Louis Bouchard (Los Angeles, California); Shoujun Xu (Houston, Texas); Elad Harel (Chicago, Illinois); Dmitry Budker (El Cerrito, California); Thomas Lowery (Berkeley, California); Micah Ledbetter (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David Wemmer (Berkeley, California); Alexander Pines (Berkeley, California); Louis Bouchard (Los Angeles, California); Shoujun Xu (Houston, Texas); Elad Harel (Chicago, Illinois); Dmitry Budker (El Cerrito, California); Thomas Lowery (Berkeley, California); Micah Ledbetter (Oakland, California) |
| ABSTRACT | A novel approach to magnetic resonance imaging is disclosed. Blood flowing through a living system is prepolarized, and then encoded. The polarization can be achieved using permanent or superconducting magnets. The polarization may be carried out upstream of the region to be encoded or at the place of encoding. In the case of an MRI of a brain, polarization of flowing blood can be effected by placing a magnet over a section of the body such as the heart upstream of the head. Alternatively, polarization and encoding can be effected at the same location. Detection occurs at a remote location, using a separate detection device such as an optical atomic magnetometer, or an inductive Faraday coil. The detector may be placed on the surface of the skin next to a blood vessel such as a jugular vein carrying blood away from the encoded region. |
| FILED | Friday, December 12, 2008 |
| APPL NO | 12/747488 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570042 | Pines et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Pines (Berkeley, California); Jeffrey Paulsen (Berkeley, California); Louis S. Bouchard (Berkeley, California); Bernhard Blumich (Roetgen, Germany) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander Pines (Berkeley, California); Jeffrey Paulsen (Berkeley, California); Louis S. Bouchard (Berkeley, California); Bernhard Blumich (Roetgen, Germany) |
| ABSTRACT | System and methods for designing and using single-sided magnet assemblies for magnetic resonance imaging (MRI) are disclosed. The single-sided magnet assemblies can include an array of permanent magnets disposed at selected positions. At least one of the permanent magnets can be configured to rotate about an axis of rotation in the range of at least +/−10 degrees and can include a magnetization having a vector component perpendicular to the axis of rotation. The single-sided magnet assemblies can further include a magnet frame that is configured to hold the permanent magnets in place while allowing the at least one of the permanent magnets to rotate about the axis of rotation. |
| FILED | Friday, August 29, 2008 |
| APPL NO | 12/675604 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/319 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570511 | Wang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jian Wang (Setauket, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Jian Wang (Setauket, New York) |
| ABSTRACT | A mobility spectrometer to measure a nanometer particle size distribution is disclosed. The mobility spectrometer includes a conduit and a detector. The conduit is configured to receive and provide fluid communication of a fluid stream having a charged nanometer particle mixture. The conduit includes a separator section configured to generate an electrical field of two dimensions transverse to a dimension associated with the flow of the charged nanometer particle mixture through the separator section to spatially separate charged nanometer particles of the charged nanometer particle mixture in said two dimensions. The detector is disposed downstream of the conduit to detect concentration and position of the spatially-separated nanometer particles. |
| FILED | Wednesday, September 08, 2010 |
| APPL NO | 12/877677 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/335 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571368 | Rinzler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles C. Rinzler (Denver, Colorado); Mark S. Zediker (Castle Rock, Colorado) |
| ASSIGNEE(S) | Foro Energy, Inc. (Littleton, Colorado) |
| INVENTOR(S) | Charles C. Rinzler (Denver, Colorado); Mark S. Zediker (Castle Rock, Colorado) |
| ABSTRACT | There are provided optical fiber configurations that provide for the delivery of laser energy, and in particular, the transmission and delivery of high power laser energy over great distances. These configurations further are hardened to protect the optical fibers from the stresses and conditions of an intended application. The configurations provide means for determining the additional fiber length (AFL) need to obtain the benefits of such additional fiber, while avoiding bending losses. |
| FILED | Wednesday, July 21, 2010 |
| APPL NO | 12/840978 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/109 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08571640 — Catheter based mid-infrared reflectance and reflectance generated absorption spectroscopy
| US 08571640 | Holman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hoi-Ying N Holman (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Hoi-Ying N Holman (Oakland, California) |
| ABSTRACT | A method of characterizing conditions in a tissue, by (a) providing a catheter that has a light source that emits light in selected wavenumbers within the range of mid-IR spectrum; (b) directing the light from the catheter to an area of tissue at a location inside a blood vessel of a subject; (c) collecting light reflected from the location and generating a reflectance spectra; and (d) comparing the reflectance spectra to a reference spectra of normal tissue, whereby a location having an increased number of absorbance peaks at said selected wavenumbers indicates a tissue inside the blood vessel containing a physiological marker for atherosclerosis. |
| FILED | Friday, December 10, 2004 |
| APPL NO | 10/582422 |
| ART UNIT | 3777 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Surgery 6/476 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571803 | Hill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colin C. Hill (Somerville, Massachusetts); Bruce W. Church (Lawrence, Massachusetts); Paul D. McDonagh (Winchester, Massachusetts); Iya G. Khalil (Boston, Massachusetts); Thomas A. Neyarapally (Boston, Massachusetts); Zachary W. Pitluk (New Haven, Connecticut) |
| ASSIGNEE(S) | Gene Network Sciences, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Colin C. Hill (Somerville, Massachusetts); Bruce W. Church (Lawrence, Massachusetts); Paul D. McDonagh (Winchester, Massachusetts); Iya G. Khalil (Boston, Massachusetts); Thomas A. Neyarapally (Boston, Massachusetts); Zachary W. Pitluk (New Haven, Connecticut) |
| ABSTRACT | The systems and methods described herein utilize a probabilistic modeling framework for reverse engineering an ensemble of causal models, from data and then forward simulating the ensemble of models to analyze and predict the behavior of the network. In certain embodiments, the systems and methods described herein include data-driven techniques for developing causal models for biological networks. Causal network models include computational representations of the causal relationships between independent variables such as a compound of interest and dependent variables such as measured DNA alterations, changes in mRNA, protein, and metabolites to phenotypic readouts of efficacy and toxicity. |
| FILED | Thursday, November 15, 2007 |
| APPL NO | 11/985618 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571834 | Gara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan Gara (Yorktown Heights, New York); David L. Satterfield (Yorktown Heights, New York); Robert E. Walkup (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alan Gara (Yorktown Heights, New York); David L. Satterfield (Yorktown Heights, New York); Robert E. Walkup (Yorktown Heights, New York) |
| ABSTRACT | Methods, systems and computer program products are disclosed for measuring a performance of a program running on a processing unit of a processing system. In one embodiment, the method comprises informing a logic unit of each instruction in the program that is executed by the processing unit, assigning a weight to each instruction, assigning the instructions to a plurality of groups, and analyzing the plurality of groups to measure one or more metrics. In one embodiment, each instruction includes an operating code portion, and the assigning includes assigning the instructions to the groups based on the operating code portions of the instructions. In an embodiment, each type of instruction is assigned to a respective one of the plurality of groups. These groups may be combined into a plurality of sets of the groups. |
| FILED | Friday, January 15, 2010 |
| APPL NO | 12/688773 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/186 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571847 | Cher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chen-Yong Cher (Port Chester, New York); Paul W. Coteus (Yorktown Heights, New York); Alan Gara (Mount Kisco, New York); Eren Kursun (Ossining, New York); David P. Paulsen (Dodge Center, Minnesota); Brian A. Schuelke (Rochester, Minnesota); John E. Sheets, II (Zumbrota, Minnesota); Shurong Tian (Mount Kisco, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Chen-Yong Cher (Port Chester, New York); Paul W. Coteus (Yorktown Heights, New York); Alan Gara (Mount Kisco, New York); Eren Kursun (Ossining, New York); David P. Paulsen (Dodge Center, Minnesota); Brian A. Schuelke (Rochester, Minnesota); John E. Sheets, II (Zumbrota, Minnesota); Shurong Tian (Mount Kisco, New York) |
| ABSTRACT | A processor-implemented method for improving efficiency of a static core turn-off in a multi-core processor with variation, the method comprising: conducting via a simulation a turn-off analysis of the multi-core processor at the multi-core processor's design stage, wherein the turn-off analysis of the multi-core processor at the multi-core processor's design stage includes a first output corresponding to a first multi-core processor core to turn off; conducting a turn-off analysis of the multi-core processor at the multi-core processor's testing stage, wherein the turn-off analysis of the multi-core processor at the multi-core processor's testing stage includes a second output corresponding to a second multi-core processor core to turn off; comparing the first output and the second output to determine if the first output is referring to the same core to turn off as the second output; outputting a third output corresponding to the first multi-core processor core if the first output and the second output are both referring to the same core to turn off. |
| FILED | Friday, March 19, 2010 |
| APPL NO | 12/727984 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572586 | Eichenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexandre E. Eichenberger (Chappaqua, New York); Michael K. Gschwind (Chappaqua, New York); John A. Gunnels (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alexandre E. Eichenberger (Chappaqua, New York); Michael K. Gschwind (Chappaqua, New York); John A. Gunnels (Yorktown Heights, New York) |
| ABSTRACT | Mechanisms for optimizing scalar code executed on a single instruction multiple data (SIMD) engine are provided. Placement of vector operation-splat operations may be determined based on an identification of scalar and SIMD operations in an original code representation. The original code representation may be modified to insert the vector operation-splat operations based on the determined placement of vector operation-splat operations to generate a first modified code representation. Placement of separate splat operations may be determined based on identification of scalar and SIMD operations in the first modified code representation. The first modified code representation may be modified to insert or delete separate splat operations based on the determined placement of the separate splat operations to generate a second modified code representation. SIMD code may be output based on the second modified code representation for execution by the SIMD engine. |
| FILED | Monday, July 23, 2012 |
| APPL NO | 13/555435 |
| ART UNIT | 2198 — Cryptography and Security |
| CURRENT CPC | Data processing: Software development, installation, and management 717/136 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572629 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ABSTRACT | Data communications in a parallel active messaging interface (‘PAMI’) of a parallel computer, the parallel computer including a plurality of compute nodes that execute a parallel application, the PAMI composed of data communications endpoints, each endpoint including a specification of data communications parameters for a thread of execution on a compute node, including specifications of a client, a context, and a task, the compute nodes and the endpoints coupled for data communications through the PAMI and through data communications resources, including receiving in an origin endpoint of the PAMI a data communications instruction, the instruction characterized by an instruction type, the instruction specifying a transmission of transfer data from the origin endpoint to a target endpoint and transmitting, in accordance with the instruction type, the transfer data from the origin endpoint to the target endpoint. |
| FILED | Thursday, December 09, 2010 |
| APPL NO | 12/963694 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/313 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08567249 | Grossman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey C. Grossman (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeffrey C. Grossman (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | An embodiment of a nanomechanical frequency detector includes a support structure and a plurality of elongated nanostructures coupled to the support structure. Each of the elongated nanostructures has a particular resonant frequency. The plurality of elongated nanostructures has a range of resonant frequencies. An embodiment of a method of identifying an object includes introducing the object to the nanomechanical resonance detector. A resonant response by at least one of the elongated nanostructures of the nanomechanical resonance detector indicates a vibrational mode of the object. An embodiment of a method of identifying a molecular species of the present invention includes introducing the molecular species to the nanomechanical resonance detector. A resonant response by at least one of the elongated nanostructures of the nanomechanical resonance detector indicates a vibrational mode of the molecular species. |
| FILED | Tuesday, August 18, 2009 |
| APPL NO | 12/543359 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/579 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568587 | Olesik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susan V. Olesik (Dublin, Ohio); Jonathan E. Clark (Nashville, Tennessee); Jeremy K. Steach (Kingsport, Tennessee); Joseph W. Zewe (Marion Center, Pennsylvania) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Susan V. Olesik (Dublin, Ohio); Jonathan E. Clark (Nashville, Tennessee); Jeremy K. Steach (Kingsport, Tennessee); Joseph W. Zewe (Marion Center, Pennsylvania) |
| ABSTRACT | A supported nanofiber medium useful for segregating chemical species is provided by selecting a polymer, selecting a substrate; and electrospinning the polymer to form a nanofiber medium on the supporting substrate. When the substrate is a planar surface, the nanofiber medium will be a mat suitable for conducting chromatographic separation. When the substrate is a filament, the nanofiber medium is an annular mat suitable for solid phase microextraction. The nanofiber media formed may be selectively cross-linked and at least partially carbonized to carbon nanofibers. The nanofiber medium is supported on the substrate without the use of binder material. |
| FILED | Friday, March 11, 2011 |
| APPL NO | 13/046552 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/198.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568611 | Ceder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gerbrand Ceder (Wellesley, Massachusetts); ByoungWoo Kang (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Gerbrand Ceder (Wellesley, Massachusetts); ByoungWoo Kang (Cambridge, Massachusetts) |
| ABSTRACT | The present invention generally relates to unique coatings for use with energy storage particles, such as lithium oxide energy storage materials. The invention provides unique coatings for particles, unique particle/coating combinations, and unique methods for making coatings and/or coated particles. In one aspect of the invention, a particle is formed having a core and a coating. The particle may comprise a core having a material such as LiFePO4, and a coating. The particle may be formed, in some embodiments, by using a non-stoichiometric combination of salts or other precursors, and sintering the same to form particles. LiFePO4 may form as the core of the particle, while the remaining materials may form a coating around the LiFePO4. Typically, the LiFePO4 is crystalline while the coating is generally amorphous, and in some instances, the coating may prevent large crystals of LiFePO4 from forming. However, in other embodiments, a coating may be applied to a particle after formation of the particle to form a core/coating structure. The particles disclosed herein may have a relatively high energy capacity, and thus may find use in batteries and other energy storage devices. Other aspects of the invention relate to devices comprising such particles, methods of making such particles, kits for making such particles, methods of promoting the making or use of such particles, and the like. |
| FILED | Friday, January 25, 2008 |
| APPL NO | 12/449116 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/182.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568681 | Kouvetakis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-xSiHx, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
| FILED | Tuesday, July 12, 2011 |
| APPL NO | 13/180961 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568690 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yi Lu (Champaign, Illinois); Mehmet Veysel Yigit (Malden, Massachusetts); Debapriya Mazumdar (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Yi Lu (Champaign, Illinois); Mehmet Veysel Yigit (Malden, Massachusetts); Debapriya Mazumdar (Urbana, Illinois) |
| ABSTRACT | The present invention provides an MRI contrast agent, comprising: MRI contrast agent particles, and oligonucleotides, attached to the particles. |
| FILED | Tuesday, July 29, 2008 |
| APPL NO | 12/182018 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568756 | Bassler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bonnie Bassler (Princeton, New Jersey); Lee Swem (San Carlos, California) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Bonnie Bassler (Princeton, New Jersey); Lee Swem (San Carlos, California) |
| ABSTRACT | Methods are provided for identifying molecules that can be used to positively and negatively manipulate quorum-sensing-mediated communication to control bacterial behavior. Small-molecule antagonists that disrupt quorum-sensing-mediated activities are identified. Methods are provided for disrupting detection of acyl-homoserine lactone autoinducer in Gram-negative bacteria by contacting the bacteria with the antagonists. Methods of inhibiting quorum sensing-mediated activity in Gram-negative bacteria are provided wherein the activity is pathogenicity, bioluminescence, siderophore production, type III secretion, or metalloprotease production. |
| FILED | Tuesday, June 02, 2009 |
| APPL NO | 12/995476 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/405 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568871 | Jiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jun Jiao (Beaverton, Oregon); Haiyan Li (Portland, Oregon) |
| ASSIGNEE(S) | State of Oregon acting by and through the State Board of Higher Education on behalf of Portland State University (Portland, Oregon) |
| INVENTOR(S) | Jun Jiao (Beaverton, Oregon); Haiyan Li (Portland, Oregon) |
| ABSTRACT | Disclosed is a method for nanostructure synthesis that includes growing nanostructures on a layered structure compound at a low temperature using a solution containing a solvent and at least one precursor. The method can include synthesizing and assembling nanowires in essentially the same method step. Disclosed nanostructures and nanowires are substantially uniform in diameter and single crystal. Nanowires can intersect to form networks and can be covalently bonded at points of intersection. Disclosed nanowire networks can be substantially uniform and can form an ordered network. Nanowire networks can be used to fabricate electronic and optical devices. |
| FILED | Tuesday, October 28, 2008 |
| APPL NO | 12/290287 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/332 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569023 | Katz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Leonard Katz (Oakland, California); Jeffrey L Fortman (San Francisco, California); Jay D Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a polyketide synthase (PKS) capable of synthesizing a dicarboxylic acid (diacid). Such diacids include diketide-diacids and triketide-diacids. The invention includes recombinant nucleic acid encoding the PKS, and host cells comprising the PKS. The invention also includes methods for producing the diacids. |
| FILED | Monday, March 30, 2009 |
| APPL NO | 12/922204 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/142 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569043 | Abbott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nicholas L. Abbott (Madison, Wisconsin); Brian H. Clare (Madison, Wisconsin); Paul J. Bertics (Oregon, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nicholas L. Abbott (Madison, Wisconsin); Brian H. Clare (Madison, Wisconsin); Paul J. Bertics (Oregon, Wisconsin) |
| ABSTRACT | A method for differentiating between a post-translationally modified peptide and a peptide contained in a sample, comprising: (a) contacting the sample with a peptide attachment surface to create a peptidized surface, wherein the sample includes at least one functional group; (b) contacting the peptidized surface with a recognition reagent that selectively binds or forms a complex with the post-translationally modified peptide in the sample to provide an incubated surface; and (c) contacting a liquid crystal with the incubated surface and detecting presence of post-translationally modified peptide in the sample with the liquid crystal. |
| FILED | Thursday, July 15, 2010 |
| APPL NO | 12/837471 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569391 | Warren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott Warren (Washington, District of Columbia); Ulrich Wiesner (Ithaca, New York); Francis J. DiSalvo, Jr. (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Scott Warren (Washington, District of Columbia); Ulrich Wiesner (Ithaca, New York); Francis J. DiSalvo, Jr. (Ithaca, New York) |
| ABSTRACT | The invention provides mesostructured materials and methods of preparing mesostructured materials including metal-rich mesostructured nanoparticle-block copolymer hybrids, porous metal-nonmetal nanocomposite mesostructures, and ordered metal mesostructures with uniform pores. The nanoparticles can be metal, metal alloy, metal mixture, intermetallic, metal-carbon, metal-ceramic, semiconductor-carbon, semiconductor-ceramic, insulator-carbon or insulator-ceramic nanoparticles, or combinations thereof. A block copolymer/ligand-stabilized nanoparticle solution is cast, resulting in the formation of a metal-rich (or semiconductor-rich or insulator-rich) mesostructured nanoparticle-block copolymer hybrid. The hybrid is heated to an elevated temperature, resulting in the formation of an ordered porous nanocomposite mesostructure. A nonmetal component (e.g., carbon or ceramic) is then removed to produce an ordered mesostructure with ordered and large uniform pores. |
| FILED | Tuesday, January 13, 2009 |
| APPL NO | 12/812714 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/153 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569695 | Zewail et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ahmed H. Zewail (Pasadena, California); David J. Flannigan (Temple City, California); Brett Barwick (Berlin, Connecticut) |
| ABSTRACT | A method of obtaining PINEM images includes providing femtosecond optical pulse, generating electron pulses, and directing the electron pulses towards a sample. The method also includes overlapping the femtosecond optical pulses and the electron pulses spatially and temporally at the sample and transferring energy from the femtosecond optical pulses to the electron pulses. The method further includes detecting electron pulses having an energy greater than a zero loss value, providing imaging in space and time. |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/863742 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569737 | Tansu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nelson Tansu (Bethlehem, Pennsylvania); Xiaohang Li (Atlanta, Georgia); Hongping Zhao (Cleveland Heights, Ohio); Guangyu Liu (Bethlehem, Pennsylvania); James Foster Gilchrist (Pasadena, California); Pisist Kumnorkaew (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Nelson Tansu (Bethlehem, Pennsylvania); Xiaohang Li (Atlanta, Georgia); Hongping Zhao (Cleveland Heights, Ohio); Guangyu Liu (Bethlehem, Pennsylvania); James Foster Gilchrist (Pasadena, California); Pisist Kumnorkaew (Bethlehem, Pennsylvania) |
| ABSTRACT | A III-Nitride semiconductor LED provides broadband light emission, across all or most of the visible light wavelength spectrum, and a method for producing same. The LED includes a polarization field management template that has a three-dimensional patterned surface. The surface may be patterned with an array of hemispherical cavities, which may be formed by growing the template around a temporary template layer of spherical or other crystals. The method involves growing a quantum well layer on the patterned surface. The topographical variations in the patterned surface of the template cause corresponding topographical variations in the quantum well layer. These variations in spatial orientation of portions of the quantum well layer cause the polarization field of the quantum well layer to vary across the surface of the LED, which leads to energy transition shifting that provides “white” light emission across a broad wavelength spectrum. |
| FILED | Thursday, December 08, 2011 |
| APPL NO | 13/314685 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569741 | Scherer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Axel Scherer (Laguna Beach, California); Sameer Walavalkar (Los Angeles, California); Michael D. Henry (Altadena, California); Andrew P. Homyk (South Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Axel Scherer (Laguna Beach, California); Sameer Walavalkar (Los Angeles, California); Michael D. Henry (Altadena, California); Andrew P. Homyk (South Pasadena, California) |
| ABSTRACT | Methods for fabricating passivated silicon nanowires and an electronic arrangement thus obtained are described. Such arrangements may comprise a metal-oxide-semiconductor (MOS) structure such that the arrangements may be utilized for MOS field-effect transistors (MOSFETs) or opto-electronic switches. |
| FILED | Monday, October 31, 2011 |
| APPL NO | 13/286008 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569834 | Fonash et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen J. Fonash (State College, Pennsylvania); Yinghui Shan (State College, Pennsylvania); Somasundaram Ashok (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J. Fonash (State College, Pennsylvania); Yinghui Shan (State College, Pennsylvania); Somasundaram Ashok (University Park, Pennsylvania) |
| ABSTRACT | A gated microelectronic device is provided that has a source with a source ohmic contact with the source characterized by a source dopant type and concentration. A drain with a drain ohmic contact with the drain characterized by a drain dopant type and concentration. An intermediate channel portion characterized by a channel portion dopant type and concentration. An insulative dielectric is in contact with the channel portion and overlaid in turn by a gate. A gate contact applies a gate voltage bias to control charge carrier accumulation and depletion in the underlying channel portion. This channel portion has a dimension normal to the gate which is fully depleted in the off-state. The dopant type is the same across the source, drain and the channel portion of the device. The device on-state current is determined by the doping and, unlike a MOSFET, is not directly proportional to device capacitance. |
| FILED | Monday, April 14, 2008 |
| APPL NO | 12/102398 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/348 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569848 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chih-Wei Chang (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Chih-Wei Chang (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | Disclosed are methods and devices in which certain types of nanotubes (e.g., carbon nanotubes and boron nitride nanotubes conduct heat with high efficiency and are therefore useful in electronic-type devices. |
| FILED | Monday, July 20, 2009 |
| APPL NO | 12/505586 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/414 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569941 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wanli Yang (El Cerrito, California); Jason D. Fabbri (San Francisco, California); Nicholas A. Melosh (Menlo Park, California); Zahid Hussain (Orinda, California); Zhi-Xun Shen (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wanli Yang (El Cerrito, California); Jason D. Fabbri (San Francisco, California); Nicholas A. Melosh (Menlo Park, California); Zahid Hussain (Orinda, California); Zhi-Xun Shen (Stanford, California) |
| ABSTRACT | Provided are electron emitters based upon diamondoid monolayers, preferably self-assembled higher diamondoid monolayers. High intensity electron emission has been demonstrated employing such diamondoid monolayers, particularly when the monolayers are comprised of higher diamondoids. The application of such diamondoid monolayers can alter the band structure of substrates, as well as emit monochromatic electrons, and the high intensity electron emissions can also greatly improve the efficiency of field-effect electron emitters as applied to industrial and commercial applications. |
| FILED | Monday, April 09, 2012 |
| APPL NO | 13/442563 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/311 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570524 | Wan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xiaoke Wan (Gainesville, Florida); Jian Ge (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Xiaoke Wan (Gainesville, Florida); Jian Ge (Gainesville, Florida) |
| ABSTRACT | Calibration of an arbitrary spectrometer can use a stable monolithic interferometer as a wavelength calibration standard. Light from a polychromatic light source is input to the monolithic interferometer where it undergoes interference based on the optical path difference (OPD) of the interferometer. The resulting wavelength-modulated output beam is analyzed by a reference spectrometer to generate reference data. The output beam from the interferometer can be provided to an arbitrary spectral instrument. Wavelength calibration of the arbitrary spectral instrument may then be performed based on a comparison of the spectral instrument output with the reference data. By appropriate choice of materials for the monolithic interferometer, a highly stable structure can be fabricated that has a wide field and/or is thermally compensated. Because the interferometer is stable, the one-time generated reference data can be used over an extended period of time without re-characterization. |
| FILED | Tuesday, August 03, 2010 |
| APPL NO | 12/849046 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/451 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570649 | Truong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thai V. Truong (Pasadena, California); John M. Choi (Tujunga, California); Scott E. Fraser (LaCanada, California); Willy Supatto (Paris, France); David S. Koos (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Thai V. Truong (Pasadena, California); John M. Choi (Tujunga, California); Scott E. Fraser (LaCanada, California); Willy Supatto (Paris, France); David S. Koos (Pasadena, California) |
| ABSTRACT | An apparatus for and method of performing light sheet microscopy (LISH) and light scanning microscopy (RAPS) in a single device are provided. The dual-mode imaging microscope allows for the use of both LISH and RAPS in a single instrument. This dual-mode device will allow researchers to have access to both types of microscopy, allowing access to the widest possible selection of samples. In addition, the device will reduce the high costs and space requirements associated with owning two different microscopes (LISH and RAPS). |
| FILED | Friday, October 29, 2010 |
| APPL NO | 12/916124 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/385 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571040 | Seetharaman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Srinivasan Seetharaman (Mountain View, California); Apurv Bhartia (Austin, Texas); Sourabh Jain (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Deutsche Telekom AG (Bonn, Germany) |
| INVENTOR(S) | Srinivasan Seetharaman (Mountain View, California); Apurv Bhartia (Austin, Texas); Sourabh Jain (Minneapolis, Minnesota) |
| ABSTRACT | A method and apparatus for communicating over a network is provided. The method includes obtaining building block codes, where the building blocks codes are capable of being used together to provide an end-to-end service. The building block codes are sent to each appropriate building block controller, where each building block controller is associated with a corresponding network node. Upon receiving a first packet of a connection for the first end-to-end service, a determination as to which network nodes of the plurality of network nodes should be used as network hops for the connection, and as to, for each network node that should be used as a network hop for the connection, which building block codes should be used by the building block controller corresponding to the network node. These determinations are communicated to each of the appropriate building block controllers. |
| FILED | Monday, March 01, 2010 |
| APPL NO | 12/714766 |
| ART UNIT | 2467 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571171 | Tischenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oleg Tischenko (München, Germany); Yuan Xu (Eugene, Oregon); Christoph Hoeschen (Hebertshausen, Germany) |
| ASSIGNEE(S) | Helmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH) (Neuherberg, Germany); State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Oleg Tischenko (München, Germany); Yuan Xu (Eugene, Oregon); Christoph Hoeschen (Hebertshausen, Germany) |
| ABSTRACT | A method of reconstructing a tomographic image of a region of investigation with reduced artifacts, said method comprises the steps of (a) reconstructing a first partial image and a second partial image of the region of investigation from first and second projection profiles each of which including projection data collected at first and second different groups of parallel projection lines, resp., wherein the first and second projection profiles are provided such that streak aliasing artifacts in the first and second partial images have different spatial phases, and (b) generating the tomographic image of the region of investigation by superimposing the first and second partial images. Preferably, the first and second projection profiles are constructed such that streak aliasing artifacts in the first and second partial images have opposite spatial phases relative to each other. Furthermore, an imaging method and an imaging device for imaging a region of investigation in an object are described. |
| FILED | Friday, December 04, 2009 |
| APPL NO | 13/132841 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571328 | Shechtman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elya Shechtman (Seattle, Washington); Dan Goldman (Seattle, Washington); Connelly Barnes (Corvallis, Oregon); Adam Finkelstein (Princeton, New Jersey) |
| ASSIGNEE(S) | Adobe Systems Incorporated (San Jose, California) |
| INVENTOR(S) | Elya Shechtman (Seattle, Washington); Dan Goldman (Seattle, Washington); Connelly Barnes (Corvallis, Oregon); Adam Finkelstein (Princeton, New Jersey) |
| ABSTRACT | Determining correspondence between image regions can include: selecting first and second regions of visual content including pixels in a computer system, the first region comprising a first patch to be mapped to the second region; selecting at least two heuristics for use in mapping the first patch to the second region, the heuristics selected from the group consisting of: (i) nearby-pixel mapping evaluation; (ii) random-perturbation mapping evaluation; (iii) evaluation of multiple mapping candidates identified in an iterative search process; and (iv) enrichment to increase a collection of mapping candidates; and identifying, using the selected heuristics, at least one patch in the second region for the first patch. |
| FILED | Monday, August 16, 2010 |
| APPL NO | 12/857294 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/218 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571351 | Yang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tianzhi Yang (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tianzhi Yang (New York, New York) |
| ABSTRACT | A computer implemented method for evaluating a one-to-one mapping between a first spatial point set and a second spatial point set in nD comprising the steps of receiving a first and a second spatial point sets and a one-to-one mapping between the two spatial point sets; defining a spatial agent; generating multiple mapped (n+1)-combinations in the first point set; computing multiple affine transformations that transform the multiple mapped (n+1)-combinations to correspondents in the second point set; applying the multiple affine transformations to the spatial agent to generate multiple transformed spatial agents; and computing a distance measure using the multiple transformed spatial agents. |
| FILED | Sunday, June 03, 2012 |
| APPL NO | 13/487219 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/294 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572018 | Mishra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bhubaneswar Mishra (Great Neck, New York); Marco Antoniotti (Baldwin Place, New York); Naren Ramakrishnan (Blacksburg, Virginia) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Bhubaneswar Mishra (Great Neck, New York); Marco Antoniotti (Baldwin Place, New York); Naren Ramakrishnan (Blacksburg, Virginia) |
| ABSTRACT | A method, system and software arrangement in accordance with an exemplary embodiment of the present invention are provided to extract descriptive narrative from numerical experimental data augmented with ontological controlled vocabulary. One exemplary application of such system, method and software arrangement is in organizing gene-expression time course data in terms of biological processes that may be activated and deactivated as the biological system responds to its normal or perturbed environment. The present invention may also have biological applications to drug-or-vaccine discovery, understanding behavior of a cell in an altered diseased state (e.g., cancer, neuro-degeneration or auto-immune disease, etc.), genetically modifying a natural wild-type organism, genetic-engineering, etc. Other exemplary applications may include understanding neural behavior, market behavior of a population of users interacting on the Internet, etc. |
| FILED | Monday, June 21, 2010 |
| APPL NO | 12/803195 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/55 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572385 | Papamanthou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charalampos Papamanthou (Berkeley, California); Roberto Tamassia (Providence, Rhode Island); Nikolaos Triandopoulos (Arlington, Massachusetts) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island); Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Charalampos Papamanthou (Berkeley, California); Roberto Tamassia (Providence, Rhode Island); Nikolaos Triandopoulos (Arlington, Massachusetts) |
| ABSTRACT | A system and method for cryptographically checking the correctness of outsourced set operations performed by an untrusted server over a dynamic collection of sets that are owned (and updated) by a trusted source is disclosed. The system and method provides new authentication mechanisms that allow any entity to publicly verify a proof attesting the correctness of primitive set operations such as intersection, union, subset and set difference. Based on a novel extension of the security properties of bilinear-map accumulators as well as on a primitive called accumulation tree, the system and method achieves optimal verification and proof complexity, as well as optimal update complexity, while incurring no extra asymptotic space overhead. The method provides an efficient proof construction, adding a logarithmic overhead to the computation of the answer of a set-operation query. Applications of interest include efficient verification of keyword search and database queries. |
| FILED | Friday, July 29, 2011 |
| APPL NO | 13/194702 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/171 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572746 | Markopoulou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Athina Markopoulou (Irvine, California); Fabio Soldo (Irvine, California); Anh Le (Irvine, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Athina Markopoulou (Irvine, California); Fabio Soldo (Irvine, California); Anh Le (Irvine, California) |
| ABSTRACT | A method is provided for determining a rating of a likelihood of a victim system receiving malicious traffic from an attacker system at a point in time. The method comprises: generating a first forecast from a time series model based on past history of attacks by the attacker system; generating a second forecast from a victim neighborhood model based on similarity between the victim system and peer victim systems; generating a third forecast from a joint attacker-victim neighborhood model based on correlation between a group of attacker systems including the attacker system and a group of victim systems including the victim system; and determining the rating of the likelihood of the victim system receiving malicious traffic from the attacker system at the point in time based on the first forecast, the second forecast, and the third forecast. |
| FILED | Thursday, January 21, 2010 |
| APPL NO | 12/691631 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Information security 726/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08568877 | Ferrari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugarland, Texas); Ciro Chiappini (Austin, Texas); Jean Raymond Fakhoury (Round Rock, Texas) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugarland, Texas); Ciro Chiappini (Austin, Texas); Jean Raymond Fakhoury (Round Rock, Texas) |
| ABSTRACT | Disclosed are a variety of porous and non-porous wire-like structures of microscopic and nanoscopic scale. For instance, disclosed are structures that comprise a porous object that comprises: (i) a first region; and (ii) a second region adjacent to the first region along an axis of the object, where the first region has at least one porous property different from that of the second region. Also disclosed are structures that include: (i) a high resistivity silicon; and (ii) a cross-section that is substantially perpendicular to an axis of the object. Also disclosed are methods of making and using such structures. For instance, the present invention provides methods of making a porous object by: (i) obtaining an etchable substrate; (ii) forming on a surface of the substrate a patterned porosification assisting metal layer that has at least one opening; and (iii) subsequently exposing the substrate to a first etching solution and a second etching solution to form respectively a first region and a second region of a porous object. |
| FILED | Wednesday, March 09, 2011 |
| APPL NO | 13/044250 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569740 | Kochergin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladimir Kochergin (Christiansburg, Virginia) |
| ASSIGNEE(S) | MicroXact Inc. (Christiansburg, Virginia) |
| INVENTOR(S) | Vladimir Kochergin (Christiansburg, Virginia) |
| ABSTRACT | Growth of thermoelectric materials in the form of quantum well superlattices on three-dimensionally structured substrates provide the means to achieve high conversion efficiency of the thermoelectric module combined with inexpensiveness of fabrication and compatibility with large scale production. Thermoelectric devices utilizing thermoelectric materials in the form of quantum well semiconductor superlattices grown on three-dimensionally structured substrates provide improved thermoelectric characteristics that can be used for power generation, cooling and other applications. |
| FILED | Tuesday, January 12, 2010 |
| APPL NO | 12/686349 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570047 | Davies et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francis J. Davies (Friendswood, Texas); Jason R. Graika (Bloomington, Minnesota) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Francis J. Davies (Friendswood, Texas); Jason R. Graika (Bloomington, Minnesota) |
| ABSTRACT | A battery monitoring system utilizes a plurality of transformers interconnected with a battery having a plurality of battery cells. Windings of the transformers are driven with an excitation waveform whereupon signals are responsively detected, which indicate a health of the battery. In one embodiment, excitation windings and sense windings are separately provided for the plurality of transformers such that the excitation waveform is applied to the excitation windings and the signals are detected on the sense windings. In one embodiment, the number of sense windings and/or excitation windings is varied to permit location of underperforming battery cells utilizing a peak voltage detector. |
| FILED | Thursday, August 12, 2010 |
| APPL NO | 12/855384 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/434 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08570460 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mingxia Gu (Beachwood, Ohio); Liubov Kreminska (Kent, Ohio); Andrii Golovin (Kent, Ohio); Oleg D. Lavrentovich (Kent, Ohio) |
| ASSIGNEE(S) | Kent State University (Kent, Ohio) |
| INVENTOR(S) | Mingxia Gu (Beachwood, Ohio); Liubov Kreminska (Kent, Ohio); Andrii Golovin (Kent, Ohio); Oleg D. Lavrentovich (Kent, Ohio) |
| ABSTRACT | A liquid crystalline optical medium includes polymer stabilized liquid crystal material. The polymer stabilized liquid crystal material includes a short pitch cholesteric liquid crystal material stabilized by a polymer material. The effective phase retardation of the polarization independent liquid crystal optical medium can be controlled by external (for example, electric and magnetic) fields. |
| FILED | Tuesday, December 19, 2006 |
| APPL NO | 11/641463 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Liquid crystal cells, elements and systems 349/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571615 | Hays |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles C. Hays (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Charles C. Hays (Pasadena, California) |
| ABSTRACT | A superconducting metallic glass transition-edge sensor (MGTES) and a method for fabricating the MGTES are provided. A single-layer superconducting amorphous metal alloy is deposited on a substrate. The single-layer superconducting amorphous metal alloy is an absorber for the MGTES and is electrically connected to a circuit configured for readout and biasing to sense electromagnetic radiation. |
| FILED | Monday, September 12, 2011 |
| APPL NO | 13/230653 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/191 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571838 | McCloud |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter L. McCloud (Shoreacres, Texas) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Peter L. McCloud (Shoreacres, Texas) |
| ABSTRACT | A method, apparatus, and computer program product for modeling heat radiated by a structure. The flow of a fluid over a surface of a model of the structure is simulated. The surface has a plurality of surface elements. Heat radiated by the plurality of surface elements in response to the fluid flowing over the surface of the model of the structure is identified. An effect of heat radiated by at least a portion of the plurality of surface elements on each other is identified. A model of the heat radiated by the structure is created using the heat radiated by the plurality of surface elements and the effect of the heat radiated by at least a portion of the plurality of surface elements on each other. |
| FILED | Wednesday, August 04, 2010 |
| APPL NO | 12/850229 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08568714 | Donovan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David M. Donovan (Baltimore, Maryland); Stephen C. Becker (Baltimore, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | David M. Donovan (Baltimore, Maryland); Stephen C. Becker (Baltimore, Maryland) |
| ABSTRACT | Multi-drug resistant superbugs are a persistent problem in modern health care. LysK is a staphylococcal bacteriophage endolysin from the phage K. It is a peptidoglycan hydrolase enzyme that can lyse many staphylococcal strains and thus is a potent antimicrobial against S. aureus, including MRSA. Lysostaphin is a bacteriocin secreted by S. simulans to kill S. aureus, and has been shown to also be a potent antimicrobial for many antibiotic resistant strains of S. aureus. This study describes optimal reaction conditions for the recombinant His-tagged LysK protein, compares its MIC and antimicrobial activity to lysostaphin and demonstrates synergy when the two are used in combination against the MRSA USA300. |
| FILED | Thursday, May 21, 2009 |
| APPL NO | 12/470466 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569465 | Ralph et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Ralph (Madison, Wisconsin); John H. Grabber (Mazomanie, Wisconsin); Ronald D. Hatfield (Madison, Wisconsin); Fachuang Lu (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | John Ralph (Madison, Wisconsin); John H. Grabber (Mazomanie, Wisconsin); Ronald D. Hatfield (Madison, Wisconsin); Fachuang Lu (Madison, Wisconsin) |
| ABSTRACT | Described is an isolated lignified plant cell wall including lignin, wherein the lignin includes a ferulate residue incorporated therein, such as from coniferyl ferulate and/or sinapyl ferulate. Also described is a method to make the isolated lignified plant cell wall, and the lignin produced by the method. |
| FILED | Tuesday, July 06, 2010 |
| APPL NO | 12/830905 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569574 | Khatib et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hasan Khatib (Madison, Wisconsin); Ricky L. Monson (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hasan Khatib (Madison, Wisconsin); Ricky L. Monson (Madison, Wisconsin) |
| ABSTRACT | Single nucleotide polymorphic sites at positions 3117, 12195, 13244, 13319, and 13516 of the bovine STAT5 gene are associated with improved fertilization rate and/or improved embryo survival rate. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods. |
| FILED | Friday, November 07, 2008 |
| APPL NO | 12/267076 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569578 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiaohong Wang (Ithaca, New York); Shunwen Lu (Fargo, North Dakota) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Xiaohong Wang (Ithaca, New York); Shunwen Lu (Fargo, North Dakota) |
| ABSTRACT | Plant CLAVATA3/ESR-related (CLE) peptides have diverse roles in plant growth and development. We have isolated and characterized the function of five new CLE genes from the potato cyst nematode Globodera rostochiensis. Unlike typical plant CLEs that contain a single CLE motif, four of the five Gr-CLE genes encode CLE proteins with multiple CLE motifs. These Gr-CLEs were found to be specifically expressed within the dorsal esophageal gland cell of nematode parasitic stages, suggesting a role for their encoded proteins in plant parasitism. Overexpression of Gr-CLEs in Arabidopsis mimicked overexpression of plant CLEs and Gr-CLE proteins could rescue the Arabidopsis clv3-2 mutant phenotype when expressed within meristems. A short root phenotype was observed when synthetic GrCLE peptides were exogenously applied to roots of Arabidopsis or potato similar to the overexpression of Gr-CLEs in Arabidopsis and potato hairy roots. These results reveal that G. rostochiensis CLEs with either single or multiple CLE motifs function similarly to plant CLEs and that CLE signaling components are conserved in both Arabidopsis and potato roots. Transgenic potato hairy roots expressing Gr-CLE-1 or Gr-CLE-4 dsRNA were generated. There was an approximately 50% reduction in the average number of cysts per root in the Gr-CLE-1 or Gr-CLE-4 dsRNA transgenic lines when compared with the infected control lines, indicating that silencing nematode CLE genes through host-derived RNAi may generate novel resistance against potato cyst nematodes in transgenic potatoes. |
| FILED | Friday, July 30, 2010 |
| APPL NO | 12/847053 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/279 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569579 | Hill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John H. Hill (Ames, Iowa); Chunquan Zhang (Ames, Iowa); Steve Whitham (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | John H. Hill (Ames, Iowa); Chunquan Zhang (Ames, Iowa); Steve Whitham (Ames, Iowa) |
| ABSTRACT | The invention provides Bean pod mottle virus (BPMV) vectors useful for expression of heterologous proteins in plants such as soybean. The BPMV vectors are also useful for virus-induced gene silencing. The vectors of the invention include modifications of BPMV RNA1 sequences so that infection with the vectors produces only moderate symptoms. The vectors also comprise novel RNA2 vectors which specifically provide for non-translated VIGS constructs and further which do not require in frame insertion of heterologous sequences to be expressed. |
| FILED | Thursday, November 18, 2010 |
| APPL NO | 12/927579 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08569705 | Baltz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nathan T. Baltz (Boulder, Colorado); J. D. Sheldon Danielson (Boulder, Colorado) |
| ASSIGNEE(S) | TauTheta Instruments LLC (Fort Collins, Colorado) |
| INVENTOR(S) | Nathan T. Baltz (Boulder, Colorado); J. D. Sheldon Danielson (Boulder, Colorado) |
| ABSTRACT | Methods and apparatus for system identification operate by computing phase and amplitude using linear filters. By digitally processing the linearly filtered signals or data, the phase and amplitude based on measurements of the input and output of a system, are determined. |
| FILED | Friday, September 03, 2010 |
| APPL NO | 12/875917 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/362 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571177 | Thorne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert E. Thorne (Ithaca, New York); Benjamin Apker (Barton, New York); Eric Hunt (Interlaken, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Robert E. Thorne (Ithaca, New York); Benjamin Apker (Barton, New York); Eric Hunt (Interlaken, New York) |
| ABSTRACT | A goniometer base for X-ray crystallography comprises a magnetic steel part with a cylindrical hole, a compliant cylindrical part that is inserted into this hole, and a cylindrical tube that is press-fit into the hole and holds the compliant part in place, such that when a crystal mounting tool is inserted through the concentric holes in each part, it is positively gripped and held in place at both T=300 K and T=100 K. |
| FILED | Tuesday, March 01, 2011 |
| APPL NO | 13/037715 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/73 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572590 | Lethin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard A. Lethin (New York, New York); Allen K. Leung (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | Richard A. Lethin (New York, New York); Allen K. Leung (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York) |
| ABSTRACT | Methods, apparatus and computer software product for source code optimization are provided. In an exemplary embodiment, a first custom computing apparatus is used to optimize the execution of source code on a second computing apparatus. In this embodiment, the first custom computing apparatus contains a memory, a storage medium and at least one processor with at least one multi-stage execution unit. The second computing apparatus contains at least two multi-stage execution units that avow for parallel execution of tasks. The first custom computing apparatus optimizes the code for both parallelism and locality of operations on the second computing apparatus. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims. |
| FILED | Wednesday, September 16, 2009 |
| APPL NO | 12/561152 |
| ART UNIT | 2197 — Cryptography and Security |
| CURRENT CPC | Data processing: Software development, installation, and management 717/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08568681 | Kouvetakis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-xSiHx, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
| FILED | Tuesday, July 12, 2011 |
| APPL NO | 13/180961 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568871 | Jiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jun Jiao (Beaverton, Oregon); Haiyan Li (Portland, Oregon) |
| ASSIGNEE(S) | State of Oregon acting by and through the State Board of Higher Education on behalf of Portland State University (Portland, Oregon) |
| INVENTOR(S) | Jun Jiao (Beaverton, Oregon); Haiyan Li (Portland, Oregon) |
| ABSTRACT | Disclosed is a method for nanostructure synthesis that includes growing nanostructures on a layered structure compound at a low temperature using a solution containing a solvent and at least one precursor. The method can include synthesizing and assembling nanowires in essentially the same method step. Disclosed nanostructures and nanowires are substantially uniform in diameter and single crystal. Nanowires can intersect to form networks and can be covalently bonded at points of intersection. Disclosed nanowire networks can be substantially uniform and can form an ordered network. Nanowire networks can be used to fabricate electronic and optical devices. |
| FILED | Tuesday, October 28, 2008 |
| APPL NO | 12/290287 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/332 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571171 | Tischenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oleg Tischenko (München, Germany); Yuan Xu (Eugene, Oregon); Christoph Hoeschen (Hebertshausen, Germany) |
| ASSIGNEE(S) | Helmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH) (Neuherberg, Germany); State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Oleg Tischenko (München, Germany); Yuan Xu (Eugene, Oregon); Christoph Hoeschen (Hebertshausen, Germany) |
| ABSTRACT | A method of reconstructing a tomographic image of a region of investigation with reduced artifacts, said method comprises the steps of (a) reconstructing a first partial image and a second partial image of the region of investigation from first and second projection profiles each of which including projection data collected at first and second different groups of parallel projection lines, resp., wherein the first and second projection profiles are provided such that streak aliasing artifacts in the first and second partial images have different spatial phases, and (b) generating the tomographic image of the region of investigation by superimposing the first and second partial images. Preferably, the first and second projection profiles are constructed such that streak aliasing artifacts in the first and second partial images have opposite spatial phases relative to each other. Furthermore, an imaging method and an imaging device for imaging a region of investigation in an object are described. |
| FILED | Friday, December 04, 2009 |
| APPL NO | 13/132841 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | X-ray or gamma ray systems or devices 378/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08567247 | Shkel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrei M. Shkel (Irvine, California); Alexander A. Trusov (Irvine, California); Igor P. Prikhodko (Westminster, California); Sergei A. Zotov (Irvine, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andrei M. Shkel (Irvine, California); Alexander A. Trusov (Irvine, California); Igor P. Prikhodko (Westminster, California); Sergei A. Zotov (Irvine, California) |
| ABSTRACT | A vibratory sensor is fabricated as a three-dimensional batch-micromachined shell adapted to vibrate and support elastic wave propagation and wave precession in the shell or membrane and at least one driving electrode and preferably a plurality of driving electrodes directly or indirectly coupled to the shell to excite and sustain the elastic waves in the shell. The pattern of elastic waves is determined by the configuration of the driving electrode(s). At least one sensing electrode and preferably a plurality of sensing electrodes are provided to detect the precession of the elastic wave pattern in the shell. The rotation of the shell induces precession of the elastic wave pattern in the shell which is usable to measure the rotation angle or rate of the vibratory sensor. |
| FILED | Wednesday, September 29, 2010 |
| APPL NO | 12/893691 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571892 | Averill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard Francis Averill (Seymour, Connecticut); Jon Eisenhandler (Bristol, Connecticut); Norbert Israel Goldfield (Northampton, Massachusetts) |
| ASSIGNEE(S) | 3M Innovative Properties Company (Saint Paul, Minnesota) |
| INVENTOR(S) | Richard Francis Averill (Seymour, Connecticut); Jon Eisenhandler (Bristol, Connecticut); Norbert Israel Goldfield (Northampton, Massachusetts) |
| ABSTRACT | A method of creating a classification system for rating the nature and severity of health care requirements, including obtaining a set of medical disease codes, categorizing the medical disease codes into major disease categories, and categorizing the medical disease codes in each major disease category into episode disease categories based on severity. |
| FILED | Monday, August 21, 2006 |
| APPL NO | 11/465901 |
| ART UNIT | 3684 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08568995 | Lopes-Virella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Maria F. Lopes-Virella (Charleston, South Carolina); Gabriel T. Virella (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC Foundation for Research Development (Charleston, South Carolina); Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Maria F. Lopes-Virella (Charleston, South Carolina); Gabriel T. Virella (Charleston, South Carolina) |
| ABSTRACT | The present invention relates to the analysis of modified LDL in the context of immune complexes. In particular, ox-LDL and AGE-LDL are shown to predict the development of coronary artery disease and other micro- and macrovascular disorders, particularly in the context of diabetes. |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/885020 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569377 | Simard |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | J. Marc Simard (Baltimore, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Department of Veteran Affairs (Washington, District of Columbia); University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | J. Marc Simard (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed to therapeutic compositions targeting the NCCa-ATP channel of an astrocyte, neuron or capillary endothelial cell and methods of using same. More specifically, antagonists of the NCCa-ATP channel are contemplated. The compositions are used to prevent cell death and to treat secondary damage associated with spinal cord injury. |
| FILED | Thursday, December 09, 2010 |
| APPL NO | 12/964018 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/592 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08569874 | Colgan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Evan G. Colgan (Chestnut Ridge, New York); Monty M. Denneau (Puddingdale, New York); Sampath Purushothaman (Yorktown Heights, New York); Klmberley A. Kelly (Pleasant Valley, New York); Roy R. Yu (Poughkeepsie, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Evan G. Colgan (Chestnut Ridge, New York); Monty M. Denneau (Puddingdale, New York); Sampath Purushothaman (Yorktown Heights, New York); Klmberley A. Kelly (Pleasant Valley, New York); Roy R. Yu (Poughkeepsie, New York) |
| ABSTRACT | A chip stack structure includes a logic chip having an active device surface, and memory slices of a memory unit vertically aligned such that a surface of the memory slices is oriented perpendicular to the active device surface of the logic chip. The chip stack structure also includes wiring patterned on an upper surface of the memory slices, the wiring electrically connecting memory leads of the memory slices to logic grids corresponding to logic grid connections of the logic chip. |
| FILED | Wednesday, March 09, 2011 |
| APPL NO | 13/043749 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/686 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08572107 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wei Fan (Hawthorne, New York); Jing Gao (Urbana, Illinois); Srinivasan Parthasarathy (Hawthorne, New York); Deepak Turaga (Hawthorne, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Wei Fan (Hawthorne, New York); Jing Gao (Urbana, Illinois); Srinivasan Parthasarathy (Hawthorne, New York); Deepak Turaga (Hawthorne, New York) |
| ABSTRACT | A horizontal anomaly detection method includes receiving at plurality of objects described in a plurality of information sources, wherein each individual information source captures a plurality of similarity relationships between the objects, combining the information sources to determine a similarity matrix whose entries represent quantitative scores of similarity between pairs of the objects, and identifying at least one horizontal anomaly of the objects within the similarity matrix, wherein the horizontal anomalies are anomalous relationships across the plurality of information sources. |
| FILED | Friday, December 09, 2011 |
| APPL NO | 13/316178 |
| ART UNIT | 2156 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/758 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 08569691 | Cambron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott Cambron (Louisville, Kentucky); Thomas J. Roussel (Louisville, Kentucky); Robert S. Keynton (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation (Louisville, Kentucky) |
| INVENTOR(S) | Scott Cambron (Louisville, Kentucky); Thomas J. Roussel (Louisville, Kentucky); Robert S. Keynton (Louisville, Kentucky) |
| ABSTRACT | An interchangeable preconcentrator assembly for delivering an analyte to an analysis instrument. The assembly includes a housing defining an inner chamber. An inlet is in fluid communication with the inner chamber, an outlet is in fluid communication with the inner chamber for delivering fluid to the inlet of the analysis instrument, and an exhaust outlet is in fluid communication with the inner chamber. A plurality of removable preconcentrator packages are disposed within the inner chamber. Each of the removable preconcentrator packages including a microscale preconcentrator. A fluid flow path is defined between the inlet and the inner chamber. A first fluid flow path is defined between the preconcentrators and the exhaust outlet, and a second fluid flow path is defined between the preconcentrators and the outlet. A selectably operable valve directs fluid flow from the inner chamber into either the first fluid flow path or the second fluid flow path. |
| FILED | Tuesday, November 23, 2010 |
| APPL NO | 12/953108 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08569428 | Dorgan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John R. Dorgan (Golden, Colorado); Birgit Braun (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John R. Dorgan (Golden, Colorado); Birgit Braun (Golden, Colorado) |
| ABSTRACT | The invention provides methods of producing composite polymers by combining fillers with polymers in the presence of pre-formed high molecular weight polymer. Monomer polymerization can be initiated through the addition of initiators or by reactive chemical groups on the surface of the fibers. The composite materials formed possess superior mechanical properties compared to similar polymer composites made by either purely mechanical mixing or solely polymerization of monomers in the presence of the fillers. |
| FILED | Monday, June 08, 2009 |
| APPL NO | 12/480599 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 525/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 08568681 | Kouvetakis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | John Kouvetakis (Mesa, Arizona); Cole J. Ritter (Phoenix, Arizona); John Tolle (Gilbert, Arizona) |
| ABSTRACT | A method is provided for synthesizing silicon-germanium hydride compounds of the formula (H3Ge)4-xSiHx, wherein x=0, 1, 2 or 3. The method includes combining a silane triflate with a compound having a GeH3 ligand under conditions whereby the silicon-germanium hydride is formed. The compound having the GeH3 ligand is selected from the group consisting of KGeH3, NaGeH3 and MR3GeH3, wherein M is a Group IV element and R is an organic ligand. The silane triflate can be HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x. The method can be used to synthesize trisilane, (H3Si)2SiH2, and the iso-tetrasilane analog, (H3Si)3SiH, by combining a silane triflate with a compound comprising a SiH3 ligand under conditions whereby the silicon hydride is formed. The silane triflate can include HxSi(OSO2CF3)4-x or HxSi(OSO2C4F9)4-x wherein x=1 or 2. A method for synthesizing (H3Ge)2SiH2 includes combining H3GeSiH2(OSO2CF3) with KGeH3 under conditions whereby (H3Ge)2SiH2 is formed. |
| FILED | Tuesday, July 12, 2011 |
| APPL NO | 13/180961 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Smithsonian Institution (SI)
| US 08569245 | Luesch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hendrik Luesch (Gainesville, Florida); Valerie J. Paul (Fort Pierce, Florida); Jason C. Kwan (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Smithsonian Institution (Washington, District of Columbia) |
| INVENTOR(S) | Hendrik Luesch (Gainesville, Florida); Valerie J. Paul (Fort Pierce, Florida); Jason C. Kwan (Salt Lake City, Utah) |
| ABSTRACT | This invention relates to grassystatins A, B and C, and their isolated or purified forms. The compounds of the invention are useful as aspartic protease, gamma secretase, or metalloprotease inhibitors. Methods of using the compounds and compositions thereof are also disclosed. |
| FILED | Saturday, June 26, 2010 |
| APPL NO | 13/380775 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/20.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08567041 | Roper |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher S. Roper (Pacific Palisades, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Christopher S. Roper (Pacific Palisades, California) |
| ABSTRACT | A heated resonator includes a base substrate, a piezoelectric piece having a thickness and a top side and a bottom side, a first electrode on the top side, a second electrode opposite the first electrode on the bottom side, an anchor connected between the piezoelectric piece and the base substrate, and a heater on the piezoelectric material. A thermal resistor region in the piezoelectric piece is between the heater and the anchor. |
| FILED | Wednesday, June 15, 2011 |
| APPL NO | 13/161118 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/594 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568524 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bowen Li (Chassell, Michigan); Ralph Hodek (Chassell, Michigan); Domenic Popko (Lake Linden, Michigan); Jiann-Yang Hwang (Chassell, Michigan) |
| ASSIGNEE(S) | Michigan Technology University (Houghton, Michigan) |
| INVENTOR(S) | Bowen Li (Chassell, Michigan); Ralph Hodek (Chassell, Michigan); Domenic Popko (Lake Linden, Michigan); Jiann-Yang Hwang (Chassell, Michigan) |
| ABSTRACT | Provided are compositions comprising stamp sand granules embedded in asphalt, where the stamp sand granules comprise a silane coating. Additionally provided are methods of making a silane-coated stamp sand, the methods comprising combining stamp sand granules and a silane solution to form a mixture and drying the mixture. Additionally provided are methods of covering a surface, the methods comprising combining silane-coated particles and asphalt to provide a mixture and distributing the mixture on the surface. |
| FILED | Friday, March 25, 2011 |
| APPL NO | 13/072267 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compositions: Coating or plastic 16/281.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08568736 | Gardella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas J. Gardella (Needham, Massachusetts); Henry M. Kronenberg (Belmont, Massachusetts); John T. Potts, Jr. (Newton, Massachusetts); Harald T. Juppner (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Thomas J. Gardella (Needham, Massachusetts); Henry M. Kronenberg (Belmont, Massachusetts); John T. Potts, Jr. (Newton, Massachusetts); Harald T. Juppner (Cambridge, Massachusetts) |
| ABSTRACT | Novel parathyroid hormone (PTH) polypeptide derivatives are disclosed, as are pharmaceutical compositions containing said polypeptides, and synthetic and recombinant methods for producing said polypeptides. Also disclosed are methods for treating mammalian conditions characterized by decreases in bone mass using therapeutically effective pharmaceutical compositions containing said polypeptides. Also disclosed are methods for screening candidate compounds of the invention for antagonistic or agonistic effects on parathyroid hormone receptor action. Also disclosed are diagnostic and therapeutic methods of said compounds. |
| FILED | Friday, March 21, 2008 |
| APPL NO | 12/053149 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/198.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569028 | Jin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xixuan Jin (Greenville, Mississippi); Daniel B. Custis (Van Wert, Ohio) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Xixuan Jin (Greenville, Mississippi); Daniel B. Custis (Van Wert, Ohio) |
| ABSTRACT | A method for encapsulation of microparticles (e.g., fungal conidia), involving (i) suspending microparticles in an aqueous solution containing at least one sugar to form an aqueous suspension wherein the concentration of said sugar is about 0.1 to 10% w/v, and (ii) spray drying said aqueous suspension with a spray dryer, wherein the inlet temperature of said spray dryer is about 40° C. to about 140° C. and the outlet temperature of said spray dryer is about 20° C. to about 80° C. |
| FILED | Wednesday, June 09, 2010 |
| APPL NO | 12/797087 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/178 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08569675 | Yap et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Yap (Newbury Park, California); Monica Minden (Calabasas, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Daniel Yap (Newbury Park, California); Monica Minden (Calabasas, California) |
| ABSTRACT | The invention is a Demodulator for an Optical Analog Pulse Position Modulated signal suitable for inclusion in receivers for Free Space Optical communication systems. In one embodiment the Demodulator may use the pulse position modulated optical information signal and the clock signal with different wavelengths. By proper biasing of a Semiconductor Optical Amplifier and selection of wavelengths for the information signal and the clock signal, the performance of the Demodulator is made insensitive to noise in the received signals. |
| FILED | Thursday, March 10, 2011 |
| APPL NO | 13/045072 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/214.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08571835 | Farrow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Reginald Conway Farrow (Somerset, New Jersey); Gordon Albert Thomas (Princeton, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Reginald Conway Farrow (Somerset, New Jersey); Gordon Albert Thomas (Princeton, New Jersey) |
| ABSTRACT | A vibration-powered impact recording device that harvests power from vibrations that affect the device is provided. The recording device is affixed to an object and includes a vibration limit detection and recordation system. The system can include a suitable part that is fixed to the object, and a mass (or other suitable part) that is less firmly attached, with the relative motion between the two parts producing an electrical voltage. The electrical voltage can be used to power an information storage unit that records the details of the impact and optionally other sensors which record other parameters such as temperature, humidity etc. at the time of impact. |
| FILED | Wednesday, June 02, 2010 |
| APPL NO | 12/792372 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/187 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, October 29, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20131029.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page