FedInvent™ Patents
Patent Details for Tuesday, December 10, 2013
This page was updated on Monday, March 27, 2023 at 03:54 AM GMT
Department of Health and Human Services (HHS)
US 08602994 | Zheng et al. |
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APPLICANT(S) | Yi Zheng (Cold Spring, Minnesota); Aiping Yao (St. Cloud, Minnesota); James F. Greenleaf (Rochester, Minnesota); Shigao Chen (Rochester, Minnesota); Matthew W. Urban (Rochester, Minnesota) |
ASSIGNEE(S) | MAYO Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Yi Zheng (Cold Spring, Minnesota); Aiping Yao (St. Cloud, Minnesota); James F. Greenleaf (Rochester, Minnesota); Shigao Chen (Rochester, Minnesota); Matthew W. Urban (Rochester, Minnesota) |
ABSTRACT | A method for measuring a mechanical property of a subject includes using an ultrasound transducer to apply ultrasonic vibration pulses to a location in a subject in order to induce shear waves at multiple prescribed orthogonal frequencies in the subject. The ultrasound transducer is directed by an excitation signal that is composed of multiple orthogonal basis functions, each having a given frequency component corresponding to the prescribed orthogonal frequencies. The power level of each orthogonal basis function is independently adjustable. The excitation signal can be sparsely sampled, or portions of the excitation signal can be removed in order to improve tissue vibration and to provide for the interleaving ultrasonic vibration and detection pulses. Ultrasonic detection pulses are applied to at least one motion detection point, from which echo signals are received. From the received echo signals, a motion signal is determined, from which mechanical properties of the subject are calculated. |
FILED | Tuesday, March 09, 2010 |
APPL NO | 13/254227 |
ART UNIT | 3768 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Surgery 6/438 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08602998 | Conrad et al. |
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APPLICANT(S) | Kirk P Conrad (Cranberry Twp., Pennsylvania); Sanjeev G Shroff (Pittsburg, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Kirk P Conrad (Cranberry Twp., Pennsylvania); Sanjeev G Shroff (Pittsburg, Pennsylvania) |
ABSTRACT | The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness. |
FILED | Thursday, January 06, 2011 |
APPL NO | 12/985714 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/485 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603416 | Beebe et al. |
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APPLICANT(S) | David J. Beebe (Monona, Wisconsin); Scott M. Barry (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Scott M. Barry (Madison, Wisconsin) |
ABSTRACT | A device and method are provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a phase-gate zone for receiving an isolation buffer therein. An output zone receives a reagent therein. A force is movable between a first position adjacent the input zone and a second position adjacent the output zone. The force urges the fraction-bound solid phase substrate from the input zone, through the phase-gate zone and into the output zone. |
FILED | Friday, February 26, 2010 |
APPL NO | 12/713950 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/527 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603435 | Miao et al. |
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APPLICANT(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Albuquerque, New Mexico) |
ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. The present invention represents a step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
FILED | Monday, January 12, 2009 |
APPL NO | 12/811946 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603457 | Yu et al. |
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APPLICANT(S) | Yi-Tao Yu (Pittsford, New York); Xinliang Zhao (Rochester, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Yi-Tao Yu (Pittsford, New York); Xinliang Zhao (Rochester, New York) |
ABSTRACT | Methods for affecting mRNA expression or translation through the modification of pre-mRNA or mRNA transcripts are described. In one embodiment of the methods of the present invention, the branch point adenosine of a pre-mRNA transcript is 2′-O-methylated to block splicing and subsequent expression of the protein encoded by the transcript. In another embodiment, a uridine residue in a nonsense stop codon may be modified to pseudouridine, causing the translation machinery to read through the nonsense stop codon and translate a full length protein. |
FILED | Friday, December 01, 2006 |
APPL NO | 11/606995 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603468 | Zhang et al. |
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APPLICANT(S) | Pei Zhang (Rockville, Maryland); Marian Major (Alexandria, Virginia); Stephen Feinstone (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Pei Zhang (Rockville, Maryland); Marian Major (Alexandria, Virginia); Stephen Feinstone (Washington, District of Columbia) |
ABSTRACT | Aspects of the present invention concern compositions that induce and/or improve an immune response to hepatitis C virus (HCV). Methods of making and using compositions that include epitopes of the HCV E2 structural protein involved in promoting or inhibiting neutralization of HCV are provided. |
FILED | Tuesday, November 04, 2008 |
APPL NO | 12/741612 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603472 | Zaghouani et al. |
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APPLICANT(S) | Habib Zaghouani (Columbia, Missouri); Renu Jain (Columbia, Missouri) |
ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
INVENTOR(S) | Habib Zaghouani (Columbia, Missouri); Renu Jain (Columbia, Missouri) |
ABSTRACT | The present invention relates generally to methods and compositions for treatment of, including reversing, pre-diabetes. More specifically, the present invention relates to the administration of a fusion protein comprising at least one immunoglobulin having one or more diabetogenic epitopes including, inter alia, GAD2, inserted within a variable region thereof, for treating or reversing pre-diabetes in a subject. |
FILED | Monday, June 19, 2006 |
APPL NO | 11/425084 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603485 | McNeel et al. |
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APPLICANT(S) | Douglas G. McNeel (Madison, Wisconsin); William J. Burlingham (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Douglas G. McNeel (Madison, Wisconsin); William J. Burlingham (Madison, Wisconsin) |
ABSTRACT | The present invention relates to antigen-specific immune regulatory response. Methods for detecting an antigen-specific immune regulatory response, methods for selecting candidate vaccine recipients, and methods for improved vaccination strategies are presented. |
FILED | Thursday, January 05, 2012 |
APPL NO | 13/343975 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603490 | Ruprecht |
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APPLICANT(S) | Ruth M. Ruprecht (Boston, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Ruth M. Ruprecht (Boston, Massachusetts) |
ABSTRACT | The invention provides methods and compositions for raising an immune response in a subject by administering an HIV antigen. The HIV antigens include HIV clade C polynucleotides and polypeptides. The invention also provides for recombinant HIV viral particles and compositions. |
FILED | Monday, September 29, 2008 |
APPL NO | 12/286159 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/208.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603522 | Bartels et al. |
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APPLICANT(S) | Stephen Paul Bartels (Pittsford, New York); Cara Larraine Baustian (Palisades, New York); George Edwin Bunce (Blacksburg, Virginia); Leon Ellenbogen (New City, New York); Frederick L. Ferris, III (Columbia, Massachusetts); Jin Kinoshita (El Macero, California); James Cecil Smith, Jr. (Glenn Dale, Maryland); David A. Souerwine (Pittsford, New York) |
ASSIGNEE(S) | Bausch and Lomb Incorporated (Rochester, New York) |
INVENTOR(S) | Stephen Paul Bartels (Pittsford, New York); Cara Larraine Baustian (Palisades, New York); George Edwin Bunce (Blacksburg, Virginia); Leon Ellenbogen (New City, New York); Frederick L. Ferris, III (Columbia, Massachusetts); Jin Kinoshita (El Macero, California); James Cecil Smith, Jr. (Glenn Dale, Maryland); David A. Souerwine (Pittsford, New York) |
ABSTRACT | A daily nutritional or dietary supplement composition that strengthens and promotes retinal health through the prevention, stabilization, reversal and/or treatment of visual acuity loss by reducing the risk of developing late stage or advanced age-related macular degeneration in persons with early age-related macular degeneration. The ingredients of the daily nutritional or dietary supplement composition include vitamin C, vitamin E, lutein, zinc and copper. The ingredients are preferably provided in a tablet form suitable for oral ingestion. |
FILED | Thursday, January 13, 2005 |
APPL NO | 11/034656 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/464 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603529 | Zion et al. |
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APPLICANT(S) | Todd C. Zion (Marblehead, Massachusetts); Thomas M. Lancaster (Stoneham, Massachusetts) |
ASSIGNEE(S) | Smartcells, Inc. (Rahway, New Jersey) |
INVENTOR(S) | Todd C. Zion (Marblehead, Massachusetts); Thomas M. Lancaster (Stoneham, Massachusetts) |
ABSTRACT | In one aspect, the disclosure provides cross-linked materials that include multivalent polynucleotide aptamers that bind a target molecule; and conjugates that include two or more separate affinity ligands bound to a conjugate framework, wherein the two or more affinity ligands compete with the target molecule for binding with the aptamers and wherein conjugates are cross-linked within the material as a result of non-covalent interactions between aptamers and affinity ligands on different conjugates. These materials are designed to release amounts of conjugate in response to desired concentrations of the target molecule. Depending on the end application, in various embodiments, the conjugates may also include a drug and/or a detectable label. The drug, detectable label and affinity ligands may be covalently or non-covalently bound to the conjugate framework. |
FILED | Wednesday, January 27, 2010 |
APPL NO | 13/145531 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603532 | Lippard et al. |
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APPLICANT(S) | Stephen J. Lippard (Cambridge, Massachusetts); Shanta Dhar (Athens, Georgia); Omid C. Farokhzad (Chestnut Hill, Massachusetts); Frank X. Gu (Waterloo, Canada); Nagesh Kolishetti (Athens, Georgia) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Stephen J. Lippard (Cambridge, Massachusetts); Shanta Dhar (Athens, Georgia); Omid C. Farokhzad (Chestnut Hill, Massachusetts); Frank X. Gu (Waterloo, Canada); Nagesh Kolishetti (Athens, Georgia) |
ABSTRACT | The present invention provides compositions, preparations, formulations, kits, and methods useful for treating subjects having cancer or at risk of developing cancer. Some embodiments of the invention may comprise a composition comprising a plurality of particles comprising a platinum(IV) therapeutically active precursor. |
FILED | Tuesday, October 20, 2009 |
APPL NO | 13/122615 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5107 (20130101) Original (OR) Class A61K 9/5115 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603734 | Zhang et al. |
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APPLICANT(S) | Hui Zhang (Baltimore, Maryland); Yan Li (Middle River, Maryland); Lori J. Sokoll (Owings Mills, Maryland); Zhen Zhang (Dayton, Maryland); Daniel W. Chan (Clarksville, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Hui Zhang (Baltimore, Maryland); Yan Li (Middle River, Maryland); Lori J. Sokoll (Owings Mills, Maryland); Zhen Zhang (Dayton, Maryland); Daniel W. Chan (Clarksville, Maryland) |
ABSTRACT | The instant invention provides methods and compositions for the detection of prostate cancer is a subject. In one embodiment, a method of detecting prostate cancer in a subject comprises the steps of (a) detecting the presence of at least one biomarker listed in Table 1 in a serum sample, wherein the presence of the biomarker in the serum sample is indicative of prostate cancer. |
FILED | Wednesday, June 04, 2008 |
APPL NO | 12/663191 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603736 | Petropoulos |
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APPLICANT(S) | Christos J. Petropoulos (Half Moon Bay, California) |
ASSIGNEE(S) | Monogram Biosciences, Inc. (South San Francisco, California) |
INVENTOR(S) | Christos J. Petropoulos (Half Moon Bay, California) |
ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is resistance to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor. |
FILED | Monday, June 06, 2005 |
APPL NO | 11/146879 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603738 | Condeelis et al. |
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APPLICANT(S) | John S. Condeelis (Bronx, New York); Sumanta Goswami (Larchmont, New York); Frank Gertler (Boston, New York); Paola Nisticò (Rome, Italy) |
ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York); Massachusetts Institute of Technology (Cambridge, Massachusetts); IFO-Regina Elena Cancer Institute (Rome, Italy) |
INVENTOR(S) | John S. Condeelis (Bronx, New York); Sumanta Goswami (Larchmont, New York); Frank Gertler (Boston, New York); Paola Nisticò (Rome, Italy) |
ABSTRACT | Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena. |
FILED | Friday, July 31, 2009 |
APPL NO | 12/462324 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603744 | Croce et al. |
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APPLICANT(S) | Carlo M. Croce (Columbus, Ohio); George A. Calin (Pearland, Texas); Stefano Volinia (Ferrara, Italy) |
ASSIGNEE(S) | The Ohio State University (Columbus, Ohio) |
INVENTOR(S) | Carlo M. Croce (Columbus, Ohio); George A. Calin (Pearland, Texas); Stefano Volinia (Ferrara, Italy) |
ABSTRACT | The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis. |
FILED | Tuesday, February 28, 2012 |
APPL NO | 13/406605 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603745 | Grody et al. |
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APPLICANT(S) | Wayne W. Grody (Pacific Palisades, California); Michael R. Jarvis (Los Angeles, California); Ramaswamy K. Iyer (Gahanna, Ohio); Laurina O. Williams (Lawrenceville, Georgia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services, Center for Disease Control and Prevention (Atlanta, Georgia); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Wayne W. Grody (Pacific Palisades, California); Michael R. Jarvis (Los Angeles, California); Ramaswamy K. Iyer (Gahanna, Ohio); Laurina O. Williams (Lawrenceville, Georgia) |
ABSTRACT | Disclosed are artificial compositions that can be used as positive controls in a genetic testing assay, such as a diagnostic assay for a particular genetic disease. Such controls can be used to confirm the presence or absence of a particular mutation. Also provided are methods of generating such compositions, and methods of their use. |
FILED | Friday, March 11, 2005 |
APPL NO | 10/598589 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603749 | Gillevet |
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APPLICANT(S) | Patrick M. Gillevet (Oakton, Virginia) |
ASSIGNEE(S) | Biospherex, LLC (Potomac Falls, Virginia) |
INVENTOR(S) | Patrick M. Gillevet (Oakton, Virginia) |
ABSTRACT | Embodiments of the invention herein described relate to multiplex polynucleotide sequence analysis without the use of size separation methods or blotting. In certain particulars the invention relates to multiplex sequencing using massively parallel sequencing methods, such as pyrosequencing methods and sequencing by synthesis. The invention provides increased throughput, increased accuracy of enumerating sample components, and the ability to analyze greater numbers of samples simultaneously or serially on presently available systems, as well as others yet to be developed. In certain of its embodiments the invention relates to the analysis of complex microbial communities, particularly to in-depth analysis thereof in large numbers of samples. |
FILED | Thursday, November 15, 2007 |
APPL NO | 12/515262 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603752 | Hood et al. |
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APPLICANT(S) | Leroy Hood (Seattle, Washington); Biaoyang Lin (Bothell, Washington) |
ASSIGNEE(S) | Institute for Systems Biology (Seattle, Washington) |
INVENTOR(S) | Leroy Hood (Seattle, Washington); Biaoyang Lin (Bothell, Washington) |
ABSTRACT | The present invention relates generally to methods for identifying drug side effects by detecting perturbations in organ-specific molecular blood fingerprints. The invention further relates to methods for identifying drug-specific organ-specific molecular blood fingerprints. As such, the present invention provides compositions comprising organ-specific proteins, detection reagents for detecting such proteins, and panels and arrays for determining organ-specific molecular blood fingerprints. |
FILED | Tuesday, February 08, 2011 |
APPL NO | 13/023366 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603764 | Wang et al. |
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APPLICANT(S) | Bingcheng Wang (Solon, Ohio); Hui Miao (Rocky River, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Bingcheng Wang (Solon, Ohio); Hui Miao (Rocky River, Ohio) |
ABSTRACT | A method of detecting malignant progression of neoplastic cells in an animal includes obtaining a sample of neoplastic cells from the animal, determining a level of S897-EphA2 phosphorylation in the neoplastic cells of the samplem, and comparing the determined level of S897-EphA2 phosphorylation in the sample to a control value, wherein an increased level of S897-EphA2 phosphorylation compared to the control value is indicative of malignant progression of the neoplastic cell in the animal. |
FILED | Monday, June 07, 2010 |
APPL NO | 12/795142 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603784 | Brown et al. |
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APPLICANT(S) | Kevin Edward Brown (Kensington, Maryland); Ning Zhi (Rockville, Maryland); Peter Tijssen (Pointe-Claire, Canada); Zoltan Zadori (Montreal, Canada) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Institut National de Rechesche Scientifique (Quebec, Canada) |
INVENTOR(S) | Kevin Edward Brown (Kensington, Maryland); Ning Zhi (Rockville, Maryland); Peter Tijssen (Pointe-Claire, Canada); Zoltan Zadori (Montreal, Canada) |
ABSTRACT | The invention relates to infectious clones of parvovirus B19, methods of cloning infectious B19 clones, and methods of cloning viral genomes that have secondary DNA structures that are unstable in bacterial cells. A B19 infectious clone and methods of producing B19 infectious clones are useful for producing infectious virus. Infectious virus is useful for identifying and developing therapeutically effective compositions for treatment and/or prevention of human parvovirus B19 infections. |
FILED | Tuesday, September 29, 2009 |
APPL NO | 12/569848 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.330 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603808 | Fischer et al. |
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APPLICANT(S) | Laurent Bernard Fischer (Sainte Foy les Lyon, France); Jesus G. Valenzuela (Gaithersburg, Maryland); Jose Ribeiro (Rockville, Maryland); Shaden Kamhawi (Rockville, Maryland) |
ASSIGNEE(S) | Merial Limited (Duluth, Georgia); The United States of America As Represented by The Secretary of the Department of Health and Human Services (Rockville, Maryland) |
INVENTOR(S) | Laurent Bernard Fischer (Sainte Foy les Lyon, France); Jesus G. Valenzuela (Gaithersburg, Maryland); Jose Ribeiro (Rockville, Maryland); Shaden Kamhawi (Rockville, Maryland) |
ABSTRACT | The present invention provides vectors that contain and express in vivo or in vitro sand fly Lu. longipalpis salivary antigens that elicit an immune response in animal or human against Leishmania, vaccine compositions comprising said vectors and/or Lu. longipalpis salivary polypeptides, methods of vaccination against Leishmania, and kits for use with such methods and compositions. |
FILED | Wednesday, May 06, 2009 |
APPL NO | 12/436398 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603817 | LaFlamme et al. |
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APPLICANT(S) | Michael A. LaFlamme (Seattle, Washington); Wei-Zhong Zhu (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Michael A. LaFlamme (Seattle, Washington); Wei-Zhong Zhu (Seattle, Washington) |
ABSTRACT | The present invention is directed to methods of producing cardiomyocytes having a nodal/pacemaker phenotype and cardiomyocytes having an atrial/ventricular phenotype. Isolated populations of nodal/pacemaker and atrial/ventricular cardiomyocytes are also disclosed. Methods of treating a subject having cardiac arrhythmia and a subject in need of cardiac tissue repair using the isolated populations of nodal/pacemaker cardiomyocytes and atrial/ventricular cardiomyocytes, respectively, are also disclosed. |
FILED | Tuesday, November 03, 2009 |
APPL NO | 12/611569 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603818 | Hochedlinger et al. |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Konrad Hochedlinger (Boston, Massachusetts); Matthias Stadtfeld (New York, New York) |
ABSTRACT | In general, iPS cells are produced by delivery of stem cell-associated genes into adult somatic cells (e.g., fibroblasts). Described herein are methods for enhancing the efficiency and rate of induced pluripotent stem cell production by treating somatic cells with a transforming growth factor-beta receptor (TGFβR) inhibitor. Also described herein are iPS cell compositions made according to the methods described herein and iPS cell compositions comprising an iPS cell in an admixture with a TGFβR inhibitor. Further described herein are kits for producing iPS cells using a TGFβR inhibitor. |
FILED | Tuesday, September 25, 2012 |
APPL NO | 13/626575 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603819 | Allon et al. |
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FUNDED BY |
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APPLICANT(S) | Aliza Apple Allon (San Francisco, California); Jeffrey Charles Lotz (San Mateo, California); Richard Alan Schneider (San Francisco, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Aliza Apple Allon (San Francisco, California); Jeffrey Charles Lotz (San Mateo, California); Richard Alan Schneider (San Francisco, California) |
ABSTRACT | The present disclosure provides compositions comprising musculoskeletal cells and mesenchymal stem cells in discrete regions. The present disclosure provides systems comprising a subject composition; and methods of using a subject composition to generate cartilage, bone, tendon, muscle, intervertebral disc, or other musculoskeletal tissues. |
FILED | Friday, May 22, 2009 |
APPL NO | 12/993668 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/393 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603823 | Stafford et al. |
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FUNDED BY |
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APPLICANT(S) | Darrel W. Stafford (Carrborro, North Carolina); Tao Li (San Diego, California) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Darrel W. Stafford (Carrborro, North Carolina); Tao Li (San Diego, California) |
ABSTRACT | The present invention relates to methods and compositions for improving the productivity of recombinant vitamin K dependent protein expression in host cells. |
FILED | Wednesday, November 04, 2009 |
APPL NO | 12/612154 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603832 | Whitesides et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Whitesides (Newton, Massachusetts); Scott T. Phillips (Cambridge, Massachusetts); Andreas W. Martinez (Cambridge, Massachusetts); Manish J. Butte (Boston, Massachusetts); Amy Wong (Saratoga, California); Samuel W. Thomas (Boston, Massachusetts); Hayat Sindi (Cambridge, United Kingdom); Sarah J. Vella (Ontario, Canada); Emanuel Carrilho (Chestnut Hill, Massachusetts); Katherine A. Mirica (Waltham, Massachusetts); Yanyan Liu (Cambridge, Massachusetts) |
ABSTRACT | Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region. |
FILED | Friday, December 28, 2012 |
APPL NO | 13/730028 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603966 | Wimley et al. |
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FUNDED BY |
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APPLICANT(S) | William C. Wimley (Mandeville, Louisiana); Jessica R. Marks (Austin, Texas) |
ASSIGNEE(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
INVENTOR(S) | William C. Wimley (Mandeville, Louisiana); Jessica R. Marks (Austin, Texas) |
ABSTRACT | Described herein are compounds that comprise amino acids and their pharmaceutical compositions. Methods used to administer the compounds are described. Screening methods including those for determining translocation and leakage are also provided. |
FILED | Saturday, February 27, 2010 |
APPL NO | 13/203490 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603971 | Szeto et al. |
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FUNDED BY |
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APPLICANT(S) | Hazel H. Szeto (New York, New York); Shaoyi Liu (Palisades Park, New Jersey); Sunghee Cho (Scarsdale, New York) |
ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
INVENTOR(S) | Hazel H. Szeto (New York, New York); Shaoyi Liu (Palisades Park, New Jersey); Sunghee Cho (Scarsdale, New York) |
ABSTRACT | The invention provides a method for treating one or more complications of diabetes in a mammal. The method comprises administering to a mammal in need thereof an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3 pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 2a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1. |
FILED | Wednesday, August 04, 2010 |
APPL NO | 12/850079 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/6.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603974 | Moyle |
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FUNDED BY |
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APPLICANT(S) | William R. Moyle (Piscataway, New Jersey) |
ASSIGNEE(S) | |
INVENTOR(S) | William R. Moyle (Piscataway, New Jersey) |
ABSTRACT | This invention relates to the field of glycoprotein hormone analogs and their uses as agonists, antagonists, targeting vectors, and immunogens. In particular, this invention describes a method for stabilizing a heterodimer that permits the preparation of functional glycoprotein hormone analogs. The analogs of present invention comprise at least one alpha subunit polypeptide and at least one beta subunit polypeptide, wherein the seatbelt region of the beta subunit is linked to the alpha subunit. The invention also provides for a beta subunit polypeptide wherein the C-terminal amino acid is from residue 10 to residue 20 of the seatbelt region. |
FILED | Tuesday, May 24, 2011 |
APPL NO | 13/114861 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/9.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603978 | Strober et al. |
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FUNDED BY |
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APPLICANT(S) | Warren Strober (Bethesda, Maryland); Ivan Fuss (Kensington, Maryland); Atsushi Kitani (Rockville, Maryland); Peter Mannon (Birmingham, Alabama); Tomohiro Watanabe (Kyoto, Japan) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Humand Services (Washington, District of Columbia) |
INVENTOR(S) | Warren Strober (Bethesda, Maryland); Ivan Fuss (Kensington, Maryland); Atsushi Kitani (Rockville, Maryland); Peter Mannon (Birmingham, Alabama); Tomohiro Watanabe (Kyoto, Japan) |
ABSTRACT | The present invention provides a method of treating or preventing inflammation in a subject comprising administering to the subject an effective amount of a muramyl dipeptide (MDP). |
FILED | Friday, November 30, 2007 |
APPL NO | 12/516633 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603987 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Kyung Jin Kim (Cupertino, California); Wei-meng Zhao (Palo Alto, California); Hangil Park (San Francisco, California); Maximiliano Vasquez (Palo Alto, California) |
ASSIGNEE(S) | Galaxy Biotech, LLC (Cupertino, California) |
INVENTOR(S) | Kyung Jin Kim (Cupertino, California); Wei-meng Zhao (Palo Alto, California); Hangil Park (San Francisco, California); Maximiliano Vasquez (Palo Alto, California) |
ABSTRACT | The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient. |
FILED | Friday, October 28, 2011 |
APPL NO | 13/284838 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603992 | Ma et al. |
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FUNDED BY |
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APPLICANT(S) | Jianjie Ma (Belle Mead, New Jersey); Noah Weisleder (Elizabeth, New Jersey) |
ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey) |
INVENTOR(S) | Jianjie Ma (Belle Mead, New Jersey); Noah Weisleder (Elizabeth, New Jersey) |
ABSTRACT | Disclosed herein are compositions and methods for treatment of muscle dysfunction (including sarcopenia) and other diseases involving skeletal muscle, including age-related muscle dysfunction. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the treatment of skeletal muscle disorder, including those related to thr normal aging process. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with altered intracellular Ca2+ regulation and disrupted membrane structure that occurs when the expression levels of MG29 are reduced. |
FILED | Thursday, July 16, 2009 |
APPL NO | 12/504331 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603993 | Ma et al. |
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FUNDED BY |
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APPLICANT(S) | Jianjie Ma (Belle Mead, New Jersey); Noah Weisleder (Elizabeth, New Jersey); Hua Zhu (Piscataway, New Jersey); Peihui Lin (Piscataway, New Jersey) |
ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey) |
INVENTOR(S) | Jianjie Ma (Belle Mead, New Jersey); Noah Weisleder (Elizabeth, New Jersey); Hua Zhu (Piscataway, New Jersey); Peihui Lin (Piscataway, New Jersey) |
ABSTRACT | Disclosed herein are compositions and methods for treatment of muscle dysfunction, including diabetes. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the treatment of skeletal muscle disorders. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with altered intracellular Ca2+ regulation and disrupted membrane structure that occurs when the expression levels of MG29 are reduced. |
FILED | Friday, June 04, 2010 |
APPL NO | 12/794006 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603994 | Dawson et al. |
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FUNDED BY |
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APPLICANT(S) | Ted M. Dawson (Baltimore, Maryland); Valina L. Dawson (Baltimore, Maryland); Han Seok Ko (Lutherville Timonium, Maryland); Jooho Shin (Ellicott City, Maryland) |
ASSIGNEE(S) | Valted, LLC (Baltimore, Maryland) |
INVENTOR(S) | Ted M. Dawson (Baltimore, Maryland); Valina L. Dawson (Baltimore, Maryland); Han Seok Ko (Lutherville Timonium, Maryland); Jooho Shin (Ellicott City, Maryland) |
ABSTRACT | Parkinson's disease is caused by the preferential loss of substantia nigra dopamine neurons. A Parkin Interacting Substrate, PARIS (ZNF746) is identified. The levels of PARIS are regulated by the ubiquitin proteasome system via binding to and ubiquitination by the E3 ubiquitin ligase, parkin. PARIS is a KRAB and zinc finger protein that accumulates in models of parkin inactivation and in human brain Parkinson's disease patients. PARIS represses the expression of the transcriptional co-activator, PGC-1α and the PGC-1α target gene, NRF-1 by binding to insulin response sequences in the PGC-1α promoter. Conditional knockout of parkin in adult animals leads to progressive loss of dopamine (DA) neurons that is PARIS dependent. Overexpression of PARIS causes selective loss of DA neurons in the substantia nigra, which is reversed by either parkin or PGC-1α co-expression. The identification of PARIS provides a molecular mechanism for neurodegeneration due to parkin inactivation. |
FILED | Friday, November 11, 2011 |
APPL NO | 13/294909 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603996 | Galloway et al. |
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FUNDED BY |
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APPLICANT(S) | Katie Galloway (Pasadena, California); Christina D. Smolke (Pasadena, California); Maung Nyan Win (San Gabriel, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Katie Galloway (Pasadena, California); Christina D. Smolke (Pasadena, California); Maung Nyan Win (San Gabriel, California) |
ABSTRACT | An extensible RNA-based framework for engineering ligand-controlled gene regulatory systems, called ribozyme switches, that exhibit tunable regulation, design modularity, and target specificity is provided. These switch platforms typically contain a sensor domain, comprised of an aptamer sequence, and an actuator domain, comprised of a hammerhead ribozyme sequence. A variety of modes of standardized information transmission between these domains can be employed, and this application demonstrates a mechanism that allows for the reliable and modular assembly of functioning synthetic hammerhead ribozyme switches and regulation of ribozyme activity in response to various effectors. In some embodiments aptamer-regulated cis-acting hammerhead ribozymes are provided. |
FILED | Tuesday, March 13, 2012 |
APPL NO | 13/418507 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604004 | Kahne et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel Kahne (Brookline, Massachusetts); Suzanne Walker Kahne (Brookline, Massachusetts); Masaatsu Adachi (Nagoya, Japan); Emma Doud (Cambridge, Massachusetts); Shinichiro Fuse (Gumma, Japan); Xiaonan Lin (Mendota Heights, Minnesota); Yi Zhang (San Diego, California); Hirokazu Tsukamoto (Cambridge, Massachusetts); Bohdan Ostash (L'viv, Ukraine) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Daniel Kahne (Brookline, Massachusetts); Suzanne Walker Kahne (Brookline, Massachusetts); Masaatsu Adachi (Nagoya, Japan); Emma Doud (Cambridge, Massachusetts); Shinichiro Fuse (Gumma, Japan); Xiaonan Lin (Mendota Heights, Minnesota); Yi Zhang (San Diego, California); Hirokazu Tsukamoto (Cambridge, Massachusetts); Bohdan Ostash (L'viv, Ukraine) |
ABSTRACT | The present invention provides novel moenomycin analogs as well as pharmaceutical compositions thereof, methods of synthesis, and methods of use in treating an infection by administering an inventive compound to a subject in need thereof. The moenomycin analogs may be prepared synthetically, biosynthetically, or semi-synthetically. The analogs are particularly useful in treating or preventing infections caused by Gram-positive organisms. Certain inventive compounds may have a broader spectrum of coverage, which includes Gram-negative organisms. |
FILED | Friday, October 03, 2008 |
APPL NO | 12/681052 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/61 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604011 | Mellon |
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FUNDED BY |
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APPLICANT(S) | Synthia Mellon (San Francisco, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Synthia Mellon (San Francisco, California) |
ABSTRACT | In one aspect the present invention provides neuroactive steroids for use in the treatment of nervous system disorders, degenerative brain diseases and congenital storage diseases. In a second aspect the invention provides neuroactive steroids in combination with a Liver X Receptor (LXR) ligand to effect treatment of a nervous system condition. |
FILED | Tuesday, September 27, 2005 |
APPL NO | 11/576125 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/177 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604018 | Kahn et al. |
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FUNDED BY |
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APPLICANT(S) | Michael Kahn (Altadena, California); Masakatsu Eguchi (Bellevue, Washington) |
ASSIGNEE(S) | Institute for Chemical Genomics (Altadena, California) |
INVENTOR(S) | Michael Kahn (Altadena, California); Masakatsu Eguchi (Bellevue, Washington) |
ABSTRACT | The invention provides α-helix mimetic structures and a chemical library relating thereto. The compounds, pharmaceutical compositions comprising the compounds, and methods of the invention using the compounds, relate to the treatment of diseases including fibrosis, such as pulmonary fibrosis. |
FILED | Monday, March 28, 2011 |
APPL NO | 13/073176 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/211.90 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604074 | McKnight et al. |
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FUNDED BY |
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APPLICANT(S) | Steven L. McKnight (Dallas, Texas); Andrew A. Pieper (Plano, Texas); Joseph M. Ready (Carrollton, Texas); Jef K. De Brabander (Flower Mound, Texas) |
ASSIGNEE(S) | Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Steven L. McKnight (Dallas, Texas); Andrew A. Pieper (Plano, Texas); Joseph M. Ready (Carrollton, Texas); Jef K. De Brabander (Flower Mound, Texas) |
ABSTRACT | This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death. |
FILED | Monday, January 11, 2010 |
APPL NO | 12/685652 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/411 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604075 | Gallagher et al. |
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FUNDED BY |
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APPLICANT(S) | Michela Gallagher (Baltimore, Maryland); Rebecca Haberman (Baltimore, Maryland); Ming Teng Koh (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Michela Gallagher (Baltimore, Maryland); Rebecca Haberman (Baltimore, Maryland); Ming Teng Koh (Baltimore, Maryland) |
ABSTRACT | This invention relates to treating age-related cognitive impairment. This invention in particular relates to the use of inhibitors of synaptic vesicle protein 2A (SV2A), such as levetiracetam, seletracetam, and brivaracetam, in improving cognitive function in subjects that exhibit age-related cognitive impairment or are at risk thereof, including, without limitation, subjects having or at risk for Mild Cognitive Impairment (MCI), Age-related Cognitive Decline (ARCD) or Age-Associated Memory Impairment (AAMI). |
FILED | Wednesday, November 02, 2011 |
APPL NO | 13/287531 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/424 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604098 | Boydston et al. |
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FUNDED BY |
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APPLICANT(S) | Andrew J. Boydston (Seattle, Washington); Robert H. Grubbs (South Pasadena, California); Chris Daeffler (Pasadena, California); Nebojsa Momcilovic (Vienna, Virginia) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Andrew J. Boydston (Seattle, Washington); Robert H. Grubbs (South Pasadena, California); Chris Daeffler (Pasadena, California); Nebojsa Momcilovic (Vienna, Virginia) |
ABSTRACT | Compositions and methods for adjustable lenses are provided. In some embodiments, the lenses contain a lens matrix material, a masking compound, and a prepolymer. The lens matrix material provides structure to the lens. The masking compound is capable of blocking polymerization or crosslinking of the prepolymer, until photoisomerization of the compound is triggered, and the compound is converted from a first isomer to a second isomer having a different absorption profile. The prepolymer is a composition that can undergo a polymerization or crosslinking reaction upon photoinitiation to alter one or more of the properties of the lenses. |
FILED | Wednesday, July 06, 2011 |
APPL NO | 13/177483 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 522/99 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604163 | Ryazanov et al. |
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FUNDED BY |
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APPLICANT(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey) |
ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Bruswick, New Jersey) |
INVENTOR(S) | Alexey G. Ryazanov (Princeton, New Jersey); Benjamin E. Turk (New Haven, Connecticut) |
ABSTRACT | Assays for identifying novel compounds for inhibiting eEF2 kinase and consequence peptides employed therein. |
FILED | Monday, January 07, 2013 |
APPL NO | 13/735253 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604168 | Ney et al. |
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FUNDED BY |
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APPLICANT(S) | Denise M. Ney (Brooklyn, Wisconsin); Mark R. Etzel (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Denise M. Ney (Brooklyn, Wisconsin); Mark R. Etzel (Madison, Wisconsin) |
ABSTRACT | Medical foods containing glycomacroprotein and additional supplemented amounts of arginine, leucine, and optionally other amino acids, such as tyrosine, are disclosed. The medical foods can be used to provide the complete protein requirements for patients having metabolic disorders such as phenylketonuria. |
FILED | Friday, June 11, 2010 |
APPL NO | 12/813988 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/360 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604176 | Smolke et al. |
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FUNDED BY |
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APPLICANT(S) | Christina D. Smolke (Menlo Park, California); Stephanie J. Culler (Placentia, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Stephanie J. Culler (Placentia, California) |
ABSTRACT | The invention described herein relates to an RNA-based control device that senses the presence and/or concentration of at least one protein ligand, preferably through its protein-binding aptamer domain, and regulates a target gene expression through alternative splicing of the target gene in which the RNA-based control device is integrated. The device has uses in therapeutic as well as diagnostic applications. |
FILED | Wednesday, November 10, 2010 |
APPL NO | 12/943350 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604178 | Bottje et al. |
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FUNDED BY |
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APPLICANT(S) | Walter Bottje (Fayetteville, Arkansas); Billy Hargis (Fayetteville, Arkansas); Luc Berghman (College Station, Texas); Young Min Kwon (Springdale, Arkansas); Kimberly Cole (Raymond, Ohio); Mandy Cox (Fayetteville, Arkansas); Sherryll Layton (Fayetteville, Arkansas) |
ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas); The Texas A and M University of System (TAMU, College Station, Texas) |
INVENTOR(S) | Walter Bottje (Fayetteville, Arkansas); Billy Hargis (Fayetteville, Arkansas); Luc Berghman (College Station, Texas); Young Min Kwon (Springdale, Arkansas); Kimberly Cole (Raymond, Ohio); Mandy Cox (Fayetteville, Arkansas); Sherryll Layton (Fayetteville, Arkansas) |
ABSTRACT | Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD 154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed. |
FILED | Tuesday, September 18, 2007 |
APPL NO | 12/441851 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604216 | Bergeron, Jr. |
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FUNDED BY |
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APPLICANT(S) | Raymond J. Bergeron, Jr. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Raymond J. Bergeron, Jr. (Gainesville, Florida) |
ABSTRACT | Compounds represented by structural formulas such as Structural Formula (I): are highly efficient in clearing excess iron from an organism. The invention also discloses methods of treating conditions such as metal overload, oxidative stress, and neoplastic and preneoplastic conditions. |
FILED | Thursday, March 02, 2006 |
APPL NO | 11/367042 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 548/201 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604229 | Van Dyke et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas E. Van Dyke (West Roxbury, Massachusetts); Nicos A. Petasis (Hacienda Heights, California); Charles N. Serhan (Needham, Massachusetts) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California); Trustees of Boston University (Boston, Massachusetts); Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Thomas E. Van Dyke (West Roxbury, Massachusetts); Nicos A. Petasis (Hacienda Heights, California); Charles N. Serhan (Needham, Massachusetts) |
ABSTRACT | This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond the oral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both. |
FILED | Monday, January 09, 2012 |
APPL NO | 13/346543 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Organic compounds 554/218 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604787 | Posse |
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FUNDED BY |
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APPLICANT(S) | Stefan Posse (Albuquerque, New Mexico) |
ASSIGNEE(S) | Stefan Posse (Albuquerque, New Mexico) |
INVENTOR(S) | Stefan Posse (Albuquerque, New Mexico) |
ABSTRACT | Disclosed are MR Spectroscopy and MR Spectroscopic Imaging (MRSI) methods comprising the sequential steps of water suppression, spatial prelocalization and spatial-spectral encoding, wherein the water suppression is modified to additionally measure and correct the frequency drift, the change in magnetic field inhomogeneity in the volume of interest, and the object movement. By inserting between the water suppression RF pulse and the dephasing gradient pulses either a phase sensitive MRI encoding module, or a 1D, 2D or 3D high-speed MRSI encoding module with simultaneous acquisition of the decaying water signal it is possible to measure frequency drift, magnetic field inhomogeneity and object movement. This information is used to dynamically change the synthesizer frequency of the scanner, the shim settings and to rotate the encoded k-space. In the preferred implementation this information is computed in real-time during the ongoing scan and via feedback loop downloaded to the acquisition control unit to update the aforementioned parameters before the subsequent data acquisition. |
FILED | Wednesday, January 26, 2011 |
APPL NO | 12/931196 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/309 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605952 | Boushey et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation, Inc. (West Lafayette, Indiana) |
INVENTOR(S) | Carol Boushey (West Lafayette, Indiana); Edward John Delp (West Lafayette, Indiana); David Scott Ebert (West Lafayette, Indiana); Kyle DelMar Lutes (West Lafayette, Indiana); Deborah Kerr (Bentley, Australia) |
ABSTRACT | The present system and method provides a more precise way to record food and beverage intake than traditional methods. The present disclosure provides custom software for use in mobile computing devices that include a digital camera. Photos captured by mobile digital devices are analyzed with image processing and comparisons to certain databases to allow a user to discretely record foods eaten. Specifically, the user captures images of the meal or snack before and after eating. The foods pictured are identified. Image processing software may identify the food or provide choices for the user. Once a food is identified and volume of the food is estimated, nutrient databases are used for calculating final portion sizes and nutrient totals. |
FILED | Thursday, December 27, 2012 |
APPL NO | 13/728414 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Image analysis 382/110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605975 | Pan et al. |
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FUNDED BY |
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APPLICANT(S) | Xiaochuan M. Pan (Chicago, Illinois); Emil Sidky (Chicago, Illinois); Chien-min Kao (Wilmette, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Xiaochuan M. Pan (Chicago, Illinois); Emil Sidky (Chicago, Illinois); Chien-min Kao (Wilmette, Illinois) |
ABSTRACT | A system and method are provided for reconstructing images from limited or incomplete data, such as few view data or limited angle data or truncated data (including exterior and interior data) generated from divergent beams. In one aspect of the invention, the method and apparatus iteratively constrains the variation of an estimated image in order to reconstruct the image. As one example, a divergent beam maybe used to generate data (“actual data”). As discussed above, the actual data may be less than sufficient to exactly reconstruct the image by conventional techniques, such as FBP. In order to reconstruct an image, a first estimated image may be generated. Estimated data may be generated from the first estimated image, and compared with the actual data. The comparison of the estimated data with the actual data may include determining a difference between the estimated and actual data. The comparison may then be used to generate a new estimated image. For example, the first estimated image may be combined with an image generated from the difference data to generate a new estimated image. In order to generate the image for the next iteration, the variation of the new estimated image may be constrained. For example, the variation of the new estimated image may be at least partly constrained in order to lessen or reducing the total variation of the image. |
FILED | Monday, February 12, 2007 |
APPL NO | 12/223946 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image analysis 382/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605980 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Xin Li (Beaverton, Oregon); Charles S. Springer, Jr. (Portland, Oregon); William D. Rooney (Lake Oswego, Oregon); Wei Huang (Lake Oswego, Oregon); Jingang Xu (Hillsboro, Oregon); Ian J. Tagge (Portland, Oregon) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Xin Li (Beaverton, Oregon); Charles S. Springer, Jr. (Portland, Oregon); William D. Rooney (Lake Oswego, Oregon); Wei Huang (Lake Oswego, Oregon); Jingang Xu (Hillsboro, Oregon); Ian J. Tagge (Portland, Oregon) |
ABSTRACT | Embodiments provide a Magnetic Resonance Imaging (MRI) technique and optionally software—collectively referred to as the “shutter-speed” model—to analyze image data of cancer patients. Embodiments provide a minimally invasive, yet precisely accurate, approach to determining whether tumors are malignant or benign by distinguishing the characteristics of contrast reagent activity in benign and malignant tumors. Exemplary embodiments provide MRI measured biomarkers for tumor malignancy determination, effectively eliminating or limiting the false positives suffered by existing MRI techniques. |
FILED | Thursday, May 07, 2009 |
APPL NO | 13/125485 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image analysis 382/133 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606360 | Butson et al. |
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FUNDED BY |
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APPLICANT(S) | Christopher R. Butson (Wauwatosa, Wisconsin); Christopher B. Maks (Yardley, Pennsylvania); Cameron C. McIntyre (Cleveland, Ohio) |
ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Christopher R. Butson (Wauwatosa, Wisconsin); Christopher B. Maks (Yardley, Pennsylvania); Cameron C. McIntyre (Cleveland, Ohio) |
ABSTRACT | This document discloses, among other things, systems and methods for determining volume of activation for spinal cord stimulation (“SCS”) using a finite element model (FEM) circuit to determine a FEM of an implanted electrode and a spinal cord in which the electrode is implanted, a Fourier FEM solver circuit to calculate a potential distribution in the spinal cord using information from the FEM circuit and a capacitive component of at least one of the implanted electrode and the spinal cord, and a volume of activation (VOA) circuit to predict a VOA using the potential distribution and a neuron model. |
FILED | Friday, April 30, 2010 |
APPL NO | 12/662722 |
ART UNIT | 3766 — Digital Communications |
CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 08601790 | Fuller |
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FUNDED BY |
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APPLICANT(S) | Jerome K. Fuller (Van Nuys, California) |
ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
INVENTOR(S) | Jerome K. Fuller (Van Nuys, California) |
ABSTRACT | A hybrid rocket motor is manufactured by photopolymerizing the solid fuel grain in a stereolithography method, wherein fuel grains in a plastic matrix are deposited in layers for building a solid fuel rocket body in three dimensions for improved performance and for a compact design, the hybrid rocket motor including buried radial channels for defining a desired burn profile including the oxidizer to fuel burn ratio. |
FILED | Thursday, February 28, 2008 |
APPL NO | 12/074001 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Power plants 060/251 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08601928 | Martinez et al. |
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FUNDED BY |
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APPLICANT(S) | Martin A. Martinez (Phoenix, Arizona); Patrick Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California) |
ASSIGNEE(S) | Engineering Science Analysis Corp. (Tempe, Arizona) |
INVENTOR(S) | Martin A. Martinez (Phoenix, Arizona); Patrick Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California) |
ABSTRACT | A method and device for impeding the progress of a swimmer or a diver included a plurality of tendrils that can be launched into the path of a target and entangle the target. |
FILED | Tuesday, July 20, 2010 |
APPL NO | 12/839930 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/1.340 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08601970 | Dorsky |
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FUNDED BY |
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APPLICANT(S) | Jason M. Dorsky (Brooklyn, New York) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jason M. Dorsky (Brooklyn, New York) |
ABSTRACT | A tethered buoy housing and deployment system includes a housing for disposition in a vessel, a tether for interconnecting a portion of the housing and a buoy, a reel mounted in the housing and rotatable to unwind the tether, means for maintaining tension on the tether as the tether is unwound, and a platform and linkage assembly adapted to support the buoy and move the buoy between a vertical disposition for storage in the housing and an angled disposition for release of the buoy into an external fluid stream. |
FILED | Monday, June 13, 2011 |
APPL NO | 13/159083 |
ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ships 114/328 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08602554 | Lau et al. |
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FUNDED BY |
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APPLICANT(S) | Kenneth H. Lau (La Crescenta, California); Ronald L. Williams (Fall Brook, California) |
ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
INVENTOR(S) | Kenneth H. Lau (La Crescenta, California); Ronald L. Williams (Fall Brook, California) |
ABSTRACT | A filter or lens for common optical apparatus includes a clear center portion and an attenuating peripheral portion where the peripheral portion attenuates off-axis images and passes on-axis images with high signal to noise ratios yet not completely blocking the off-axis images, which lens is well suited for reducing off-axis glare in the optical apparatus that may be handheld optical apparatus such as binoculars, telescopes, cameras, and eyeglasses. |
FILED | Thursday, April 16, 2009 |
APPL NO | 12/386282 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/159.630 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603229 | Tatarchuk et al. |
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FUNDED BY |
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APPLICANT(S) | Bruce Tatarchuk (Auburn, Alabama); Ryan A. Sothen (Auburn, Alabama) |
ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
INVENTOR(S) | Bruce Tatarchuk (Auburn, Alabama); Ryan A. Sothen (Auburn, Alabama) |
ABSTRACT | Multi-Element Structured Arrays (MESAs) present an effective approach to utilizing high pressure drop media that previously were cost prohibitive for use in a traditional filter element. The operational velocity is significantly slowed by the incorporation of numerous elements; thus, eliminating the Darcian flow resistances of the media. The MESAs are readily fitted with two or more replaceable “filter elements” that are able to employ commercially available media, microfibrous entrapped catalyst/sorbent media, unique multilayers and more. A model capable of estimating pressure drop for flow through a pleated filter is able to be used as a design tool to predict minimum initial pressure drop, maximum filtration area, and preferred media properties with respect to permeability versus thickness thus allowing the filtration system's dirt holding capacity, filtration efficiency and operational energy cost and filtration operational and total ownership costs such as blower energy, filter procurement and shipping, maintenance personnel, filter disposal, inventory and storage, cost of money and more to be improved. |
FILED | Monday, November 03, 2008 |
APPL NO | 12/290847 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Apparatus 096/134 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603243 | VanMil et al. |
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FUNDED BY |
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APPLICANT(S) | Brenda L VanMil (Alexandria, Virginia); Kok-Keong Lew (Hillsboro, Oregon); Rachael L Myers-Ward (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); David Kurt Gaskill (Alexandria, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Brenda L VanMil (Alexandria, Virginia); Kok-Keong Lew (Hillsboro, Oregon); Rachael L Myers-Ward (Alexandria, Virginia); Charles R. Eddy, Jr. (Columbia, Maryland); David Kurt Gaskill (Alexandria, Virginia) |
ABSTRACT | A method of: supplying sources of carbon and silicon into a chemical vapor deposition chamber; collecting exhaust gases from the chamber; performing mass spectrometry on the exhaust gases; and correlating a partial pressure of a carbon species in the exhaust gases to a carbon:silicon ratio in the chamber. |
FILED | Thursday, July 31, 2008 |
APPL NO | 12/183465 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/86 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603313 | Allaway et al. |
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FUNDED BY |
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APPLICANT(S) | Michael J. Allaway (Pittsburgh, Pennsylvania); Michael J. Pawlik (Glenshaw, Pennsylvania); James E. Poole (Gibsonia, Pennsylvania); Edward E. Abbott (Canandaigua, New York) |
ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
INVENTOR(S) | Michael J. Allaway (Pittsburgh, Pennsylvania); Michael J. Pawlik (Glenshaw, Pennsylvania); James E. Poole (Gibsonia, Pennsylvania); Edward E. Abbott (Canandaigua, New York) |
ABSTRACT | An electrode assembly for use in electrophoretically depositing an electrodepositable coating composition onto a conductive substrate having a hollowed interior region therewithin includes a first counter electrode and an electrode assembly comprising a second counter electrode and a deployable primary electrode which are introduced within the hollowed out interior region during the electrodeposition process to provide a deposited electrodeposition coating on inner and outer surfaces. |
FILED | Friday, August 05, 2011 |
APPL NO | 13/198801 |
ART UNIT | 1759 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Chemistry: Electrical and wave energy 24/479 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603337 | Yelvington et al. |
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FUNDED BY |
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APPLICANT(S) | Paul E. Yelvington (Rockledge, Florida); Robert A. Damitz (Satellite Beach, Florida); Samantha J. Roman (Jacksonville, Florida); Ian T. McCarrell (Green Bay, Wisconsin) |
ASSIGNEE(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
INVENTOR(S) | Paul E. Yelvington (Rockledge, Florida); Robert A. Damitz (Satellite Beach, Florida); Samantha J. Roman (Jacksonville, Florida); Ian T. McCarrell (Green Bay, Wisconsin) |
ABSTRACT | A water heater and purifier has a membrane element and employs an exothermic and pressure-generating chemical reaction. The exothermic reaction heats water, and the gaseous reaction products pressurize an enclosure and force water through a membrane filter for purification. Disinfection of the water is achieved using heat, filtration, and optionally a chemical disinfectant. |
FILED | Thursday, October 21, 2010 |
APPL NO | 12/908895 |
ART UNIT | 3742 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Liquid purification or separation 210/261 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603381 | Berggren et al. |
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FUNDED BY |
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APPLICANT(S) | Karl K. Berggren (Arlington, Massachusetts); Stefan Harrer (Erding, Germany); Giovanni A. Salvatore (Spinete, Italy); Joel K. Yang (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Insitute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Karl K. Berggren (Arlington, Massachusetts); Stefan Harrer (Erding, Germany); Giovanni A. Salvatore (Spinete, Italy); Joel K. Yang (Cambridge, Massachusetts) |
ABSTRACT | In a method for imprinting a layer of material, a nanotemplate is impressed into a material layer, and the nanotemplate is maintained impressed in the material layer until a geometric trench corresponding to geometry of the nanotemplate is formed in the layer, and the nanotemplate is then removed from the material layer. A nanotemplate geometric trench is repeatedly formed in the material layer by nanotemplate impressions in the layer, until a final desired imprint pattern is produced in the layer. Each nanotemplate geometric trench is characterized by an extent that is a fraction of an extent of the final desired imprint pattern. The material layer is maintained in a condition for accepting nanotemplate impressions continuously throughout the nanotemplate impression repetition. |
FILED | Tuesday, October 03, 2006 |
APPL NO | 11/542474 |
ART UNIT | 1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/294 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603395 | Fries et al. |
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FUNDED BY |
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APPLICANT(S) | David P Fries (St. Petersburg, Florida); Michelle L Janowiak (Clearwater, Florida); George Steimle (St. Petersburg, Florida); Heather A Broadbent (St. Petersburg, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | David P Fries (St. Petersburg, Florida); Michelle L Janowiak (Clearwater, Florida); George Steimle (St. Petersburg, Florida); Heather A Broadbent (St. Petersburg, Florida) |
ABSTRACT | A self-propelled apparatus for analyzing a component contained in a fluid medium. The self-propelled apparatus uses kinetic energy of the apparatus to drive a fluid under analysis through the apparatus. This is accomplished by use of a conveyance system that is attached to the analytical system of the apparatus. A sensor system is used to analyze the component collected within the confines of an analysis chamber, a part of the analysis system. The invention also includes a method of using the analytical apparatus. |
FILED | Tuesday, November 10, 2009 |
APPL NO | 12/615800 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/68.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603416 | Beebe et al. |
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FUNDED BY |
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APPLICANT(S) | David J. Beebe (Monona, Wisconsin); Scott M. Barry (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Scott M. Barry (Madison, Wisconsin) |
ABSTRACT | A device and method are provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a phase-gate zone for receiving an isolation buffer therein. An output zone receives a reagent therein. A force is movable between a first position adjacent the input zone and a second position adjacent the output zone. The force urges the fraction-bound solid phase substrate from the input zone, through the phase-gate zone and into the output zone. |
FILED | Friday, February 26, 2010 |
APPL NO | 12/713950 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/527 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603452 | Koob |
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FUNDED BY |
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APPLICANT(S) | Thomas J. Koob (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Thomas J. Koob (Tampa, Florida) |
ABSTRACT | The invention comprises a biological hydrogel that is chemically stabilized with non-covalent or covalent cross-links. The biological hydrogel is used to coat surfaces of materials for submersion in marine water. Molecular dissolution at the marine water-hydrogel surface prevents attachment of fouling organisms. The rate of dissolution can be controlled by both the concentration of the biopolymer in the hydrogel and the nature and concentration of cross-linker used. Additional components, either molecular or particulate, can be added to the biological hydrogel before or after cross-linking for enhanced properties. |
FILED | Friday, May 02, 2008 |
APPL NO | 12/114106 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.90 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603485 | McNeel et al. |
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FUNDED BY |
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APPLICANT(S) | Douglas G. McNeel (Madison, Wisconsin); William J. Burlingham (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Douglas G. McNeel (Madison, Wisconsin); William J. Burlingham (Madison, Wisconsin) |
ABSTRACT | The present invention relates to antigen-specific immune regulatory response. Methods for detecting an antigen-specific immune regulatory response, methods for selecting candidate vaccine recipients, and methods for improved vaccination strategies are presented. |
FILED | Thursday, January 05, 2012 |
APPL NO | 13/343975 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603543 | Stucky et al. |
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FUNDED BY |
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APPLICANT(S) | Galen Stucky (Santa Barbara, California); Sarah Baker (Pleasanton, California); April Sawvel (Santa Barbara, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Galen Stucky (Santa Barbara, California); Sarah Baker (Pleasanton, California); April Sawvel (Santa Barbara, California) |
ABSTRACT | The present invention relates to hemostatic compositions comprising a mesocellular oxide foam and, optionally, a biologically active agent such as a procoagulant, as well as devices and methods of use to promote blood clotting. |
FILED | Wednesday, May 02, 2012 |
APPL NO | 13/462627 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/684 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603573 | Rappe et al. |
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FUNDED BY |
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APPLICANT(S) | Andrew M. Rappe (Penn Valley, Pennsylvania); Alexie Michelle Kolpak (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Andrew M. Rappe (Penn Valley, Pennsylvania); Alexie Michelle Kolpak (Philadelphia, Pennsylvania) |
ABSTRACT | Disclosed herein are perovskite ferroelectric thin-film. Also disclosed are methods of controlling the properties of ferroelectric thin films. These films can be used in a variety materials and devices, such as catalysts and storage media, respectively. |
FILED | Monday, December 03, 2007 |
APPL NO | 12/517163 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating processes 427/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603606 | Stuke et al. |
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FUNDED BY |
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APPLICANT(S) | Michael Josef Stuke (Palo Alto, California); Zhiyong Li (Redwood City, California); Shih-Yuan Wang (Palo Alto, California); Fung Suong Ou (Palo Alto, California); Min Hu (Sunnyvale, California); Wei Wu (Palo Alto, California); Lars Helge Thylen (Huddinge, Sweden) |
ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
INVENTOR(S) | Michael Josef Stuke (Palo Alto, California); Zhiyong Li (Redwood City, California); Shih-Yuan Wang (Palo Alto, California); Fung Suong Ou (Palo Alto, California); Min Hu (Sunnyvale, California); Wei Wu (Palo Alto, California); Lars Helge Thylen (Huddinge, Sweden) |
ABSTRACT | A device for Surface Enhanced Raman Scattering (SERS). The device includes a plurality of nanostructures protruding from a surface of a substrate, a SERS active metal disposed on a portion of said plurality of nanostructures, and a low friction film disposed over the plurality of nanostructures and the SERS active metal. The low friction film is to prevent adhesion between the plurality of nanostructures. |
FILED | Friday, October 29, 2010 |
APPL NO | 12/916239 |
ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/141 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603623 | Demirel et al. |
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FUNDED BY |
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APPLICANT(S) | Melik C. Demirel (State College, Pennsylvania); Alok K Singh (Springfield, Virginia); Walter J Dressick (Waldorf, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Melik C. Demirel (State College, Pennsylvania); Alok K Singh (Springfield, Virginia); Walter J Dressick (Waldorf, Maryland) |
ABSTRACT | A spatially organized polymer nanostructured thin film and a ligand adsorbate attached to the polymer nanostructured thin film and, optionally, an additional material or materials attached to the ligand adsorbate. A method for forming a structure by: providing a spatially organized polymer nanostructured thin film and a ligand adsorbate, and adsorbing the ligand adsorbate onto the thin film and, optionally, binding additional material or materials to the ligand adsorbate. |
FILED | Thursday, April 24, 2008 |
APPL NO | 12/108549 |
ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/319.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603797 | March et al. |
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FUNDED BY |
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APPLICANT(S) | John C. March (Ithaca, New York); Matthew S. Russell (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | John C. March (Ithaca, New York); Matthew S. Russell (Ithaca, New York) |
ABSTRACT | This disclosure provides methods and compositions for targeted mutagenesis of specific genes in a bacterial strain. By inducibly over-expressing error-prone polymerases such as Pol IV or Pol V in conjunction with nickase in a bacterial strain, and housing the targeted gene(s) on an episome or plasmid which contains one or more nickase recognition sequences, the targeted gene(s) can be selectively mutated at rates significantly greater than genes contained on the chromosome. The methods disclosed herein are useful for engineering desirable bacterial phenotypes and novel strains, including for example strains useful for treating or degrading waste and/or environmental contaminants, for optimizing bioprocesses, and for converting low-value feed-stock into value-added products. |
FILED | Thursday, March 17, 2011 |
APPL NO | 13/634995 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603834 | Puleo et al. |
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FUNDED BY |
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APPLICANT(S) | Christopher Michael Puleo (Glenville, New York); Christopher Fred Keimel (Schenectady, New York); Craig Patrick Galligan (Cropseyville, New York) |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Christopher Michael Puleo (Glenville, New York); Christopher Fred Keimel (Schenectady, New York); Craig Patrick Galligan (Cropseyville, New York) |
ABSTRACT | A method of actuating a valve, comprises operatively coupling the valve with an electroosmotic pump; flowing a fluid through the electroosmotic pump; and generating a fluidic pressure of at least 0.75 PSI to actuate the valve, wherein the electroosmotic pump comprises one or more thin, porous, positive electroosmotic membranes and one or more thin porous, negative electroosmotic membranes; a plurality of electrodes comprising cathodes and anodes, and a power source; wherein each of the positive and negative electroosmotic membranes are disposed alternatively and wherein at least one of the cathodes is disposed on one side of one of the membranes and at least one of the anodes is disposed on the other side of the membrane and wherein at least one of the cathodes or anodes is disposed between a positive and a negative electroosmotic membrane. |
FILED | Wednesday, January 25, 2012 |
APPL NO | 13/357729 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/180 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603949 | Arnold et al. |
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FUNDED BY |
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APPLICANT(S) | Frances H. Arnold (La Cañada, California); Christopher R. Otey (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Frances H. Arnold (La Cañada, California); Christopher R. Otey (Pasadena, California) |
ABSTRACT | The present disclosure teaches that the recombination of homologous sequences of P450 enzymes, with the aid of SCHEMA to predict a resulting protein structure, is able to generate libraries of chimeras with significant functional diversity. Additionally, the members of these libraries demonstrate superior or unexpected new properties, which correlate with other factors that are observable in the library. Thus, the making of libraries of optimized P450 enzymes, the analysis of libraries to identify an optimized subset, and the optimized chimeras with improved or altered functionalities are all taught in the present disclosure. |
FILED | Tuesday, June 15, 2004 |
APPL NO | 10/869813 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/24 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603996 | Galloway et al. |
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FUNDED BY |
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APPLICANT(S) | Katie Galloway (Pasadena, California); Christina D. Smolke (Pasadena, California); Maung Nyan Win (San Gabriel, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Katie Galloway (Pasadena, California); Christina D. Smolke (Pasadena, California); Maung Nyan Win (San Gabriel, California) |
ABSTRACT | An extensible RNA-based framework for engineering ligand-controlled gene regulatory systems, called ribozyme switches, that exhibit tunable regulation, design modularity, and target specificity is provided. These switch platforms typically contain a sensor domain, comprised of an aptamer sequence, and an actuator domain, comprised of a hammerhead ribozyme sequence. A variety of modes of standardized information transmission between these domains can be employed, and this application demonstrates a mechanism that allows for the reliable and modular assembly of functioning synthetic hammerhead ribozyme switches and regulation of ribozyme activity in response to various effectors. In some embodiments aptamer-regulated cis-acting hammerhead ribozymes are provided. |
FILED | Tuesday, March 13, 2012 |
APPL NO | 13/418507 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604152 | Webster et al. |
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FUNDED BY |
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APPLICANT(S) | Dean C. Webster (Fargo, North Dakota); Abdullah Ekin (Imperial, Pennsylvania); Stacy Sommer (Hudson, Wisconsin) |
ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
INVENTOR(S) | Dean C. Webster (Fargo, North Dakota); Abdullah Ekin (Imperial, Pennsylvania); Stacy Sommer (Hudson, Wisconsin) |
ABSTRACT | A polymeric material, prepared by reacting a mixture comprising a polyorganosiloxane having one or more isocyanate-reactive functional groups, polyisocyanate, and polyol, is provided. The isocyanate-reactive functional groups, typically one or two, are attached to only a single end of the polyorganosiloxane chains. The polymeric material may be used to form coatings on a substrate and to inhibit fouling on surfaces exposed to aqueous conditions. |
FILED | Thursday, September 13, 2012 |
APPL NO | 13/615247 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 528/38 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604158 | Beaujuge et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Pierre M. Beaujuge (Thuwal, Saudi Arabia); Stefan M. Ellinger (Visp, Switzerland); John R. Reynolds (Dunwoody, Georgia) |
ABSTRACT | Green to transmissive soluble electrochromic polymers are conjugated polymers having a plurality of repeating units where repeating units are a plurality of substituted dioxyheterocycle based donor groups coupled to an acceptor group. The conjugated polymer absorbs radiation within a first band of the visible spectrum and a second band of the visible spectrum when in a neutral state resulting in a green color and is transmissive when in an oxidized state. The polymers are soluble allowing processing of films and coatings from solution. |
FILED | Monday, February 25, 2013 |
APPL NO | 13/776236 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 528/377 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604184 | Mullis et al. |
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FUNDED BY |
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APPLICANT(S) | Kary B. Mullis (Corona del Mar, California); Jeevalatha Vivekananda (San Antonio, Texas); Johnathan Lloyd Kiel (Universal City, Texas); Ronald M. Cook (Novato, California) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Kary B. Mullis (Corona del Mar, California); Jeevalatha Vivekananda (San Antonio, Texas); Johnathan Lloyd Kiel (Universal City, Texas); Ronald M. Cook (Novato, California) |
ABSTRACT | Methods and compositions for immediately immunizing an individual against any molecule or compound are provided. The present invention is directed to an immunity linker with at least two sites; (1) at least one first binding site that binds to an immune response component in an individual, and (2) at least one second binding site that binds specifically to a desired compound or molecule, the target. The second binding sites are preferably thiolated aptamers that have the benefit of increased stability, resistance to degradation and longer circulating half life. Methods of making and using pharmaceutical compositions including immunity linker molecules having a thiolated aptamer are also provided. |
FILED | Wednesday, May 05, 2010 |
APPL NO | 12/774194 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/24.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604572 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Jian-Ping Wang (Shoreview, Minnesota); Md. Tofizur Rahman (Falcon Heights, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Md. Tofizur Rahman (Falcon Heights, Minnesota) |
ABSTRACT | A magnetic tunnel junction device comprises a fixed magnetic layer having a first side and a second side, the fixed magnetic layer having a magnetic anisotropy that is out of the film plane of the fixed magnetic layer; a stack of a plurality of bilayers adjacent to the first side of the fixed magnetic layer, each bilayer comprising a first layer comprising at least one of cobalt, iron, a CoFeB alloy, or a CoB alloy and a second layer in contact with the first layer, the second layer comprising palladium or platinum, wherein the plurality of bilayers has a magnetic anisotropy that is out of the film plane of each of the bilayers, wherein the fixed magnetic layer is exchange coupled to the stack of the plurality of bilayers, and a tunnel barrier layer in contact with the second side of the fixed magnetic layer. |
FILED | Tuesday, June 14, 2011 |
APPL NO | 13/160306 |
ART UNIT | 2892 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/421 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604664 | Chiang et al. |
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FUNDED BY |
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APPLICANT(S) | Yet-Ming Chiang (Framingham, Massachusetts); Michael J. Cima (Winchester, Massachusetts); Timothy E. Chin (San Jose, California) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Yet-Ming Chiang (Framingham, Massachusetts); Michael J. Cima (Winchester, Massachusetts); Timothy E. Chin (San Jose, California) |
ABSTRACT | The present invention provides systems, devices, and related methods, involving electrochemical actuation. In some cases, application of a voltage or current to a system or device of the invention may generate a volumetric or dimensional change, which may produce mechanical work. For example, at least a portion of the system may be constructed and arranged to be displaced from a first orientation to a second orientation. Systems such as these may be useful in various applications, including pumps (e.g., infusion pumps) and drug delivery devices, for example. |
FILED | Thursday, July 05, 2012 |
APPL NO | 13/542179 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/311 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604670 | Mahameed et al. |
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FUNDED BY |
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APPLICANT(S) | Rashed Mahameed (Umm Al-Fahem, Israel); Nipun Sinha (Philadelphia, Pennsylvania); Gianluca Piazza (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Rashed Mahameed (Umm Al-Fahem, Israel); Nipun Sinha (Philadelphia, Pennsylvania); Gianluca Piazza (Philadelphia, Pennsylvania) |
ABSTRACT | Piezoelectric switches and methods of forming piezoelectric switches. The piezoelectric switch includes first and second cantilever beam actuators. The second cantilever beam actuator has a projection that overlaps the first cantilever beam actuator in a contact region. The projection is mechanically separated from the first cantilever beam actuator by a nanogap such that the first and second cantilever beam actuators are electrically isolated from each other. Each of the first and second cantilever beam actuators includes a piezoelectric actuation layer. |
FILED | Monday, June 01, 2009 |
APPL NO | 12/994301 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Electrical generator or motor structure 310/330 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604676 | Finkel et al. |
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FUNDED BY |
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APPLICANT(S) | Peter Finkel (Downington, Pennsylvania); Ahmed H. Amin (North Attleboro, Massachusetts); Kim C. Benjamin (Portsmouth, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Peter Finkel (Downington, Pennsylvania); Ahmed H. Amin (North Attleboro, Massachusetts); Kim C. Benjamin (Portsmouth, Rhode Island) |
ABSTRACT | A piezoelectric transducer includes a single crystal piezoelectric material having a phase transition from one crystalline phase to a second crystalline phase at a predetermined stress level. A pre-stress is applied to the single crystal piezoelectric material so that the material is maintained near its phase transition point. An electrical field source is joined to the material such that, in cooperation with the pre-stress, an increase or decrease in the electrical field causes a crystalline phase transition in the single crystal piezoelectric material. Crystalline phase transition induces strain larger by an order of magnitude than that caused by the non-phase transition piezoelectric effect. |
FILED | Tuesday, March 22, 2011 |
APPL NO | 13/053577 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/187 (20130101) Original (OR) Class H01L 41/1876 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604681 | Ready et al. |
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FUNDED BY |
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APPLICANT(S) | William Judson Ready (Atlanta, Georgia); Mitchell L. R. Walker, II (Mableton, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | William Judson Ready (Atlanta, Georgia); Mitchell L. R. Walker, II (Mableton, Georgia) |
ABSTRACT | Described herein are improved ion thruster components and ion thrusters made from such components. Further described are methods of making and using the improved ion thruster components and ion thrusters made therefrom. An improved cathode includes an emitter formed from a plurality of vertically aligned carbon nanotubes. An ion thruster can include the improved cathode. |
FILED | Thursday, March 05, 2009 |
APPL NO | 12/921109 |
ART UNIT | 2879 — Optics |
CURRENT CPC | Electric lamp and discharge devices 313/311 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604951 | Sze et al. |
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FUNDED BY |
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APPLICANT(S) | Vivienne Sze (Toronto, Canada); Anantha P. Chandrakasan (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Vivienne Sze (Toronto, Canada); Anantha P. Chandrakasan (Belmont, Massachusetts) |
ABSTRACT | A system and method is provided for ordering intervals rLPS and rMPS of a range to increase speed of binary symbol decoding in a binary arithmetic decoder. The method comprises the steps of: placing rLPS at a bottom of the range; enabling subtraction for rMPS to occur in parallel with comparison of rLPS and offset; and, reducing time that it takes to decode a bin. A method is also provided for performing context selection for a given syntax element, comprising the steps of: first, comparing information regarding properties of neighboring pixels with a threshold; second, adding results of threshold comparison of neighboring pixels, to provide a secondary result; and using the secondary result to select a context. |
FILED | Wednesday, October 05, 2011 |
APPL NO | 13/253915 |
ART UNIT | 2819 — Semiconductors/Memory |
CURRENT CPC | Coded data generation or conversion 341/107 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604966 | Luk-Paszyc et al. |
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FUNDED BY |
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APPLICANT(S) | Jerzy W. Luk-Paszyc (Vorhees, New Jersey); Jonathan A. Boardman (Mt. Laurel, New Jersey) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Jerzy W. Luk-Paszyc (Vorhees, New Jersey); Jonathan A. Boardman (Mt. Laurel, New Jersey) |
ABSTRACT | A method determines the atmospheric refraction of a radar beam by utilizing a stabilized optical telescope directed toward a star near the radar target location. This allows measuring the target refraction as observed from ships at sea without a-priori knowledge of the local refraction index or weather conditions in the target area. The telescope may employ an infra-red (IR) sensor and is capable of imaging stars. The atmospheric refraction of the star light is determined by pointing the telescope based on star ephemeris data, and measuring the star image deviation from the center of the telescope's field-of-view (FOV). The corresponding refraction of the radar beam can be determined by employing a conversion factor relating the IR-to-RF atmospheric propagation characteristics. This conversion factor can be obtained by dedicated tracking measurements. |
FILED | Monday, July 11, 2011 |
APPL NO | 13/180397 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/52 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605004 | Legare |
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FUNDED BY |
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APPLICANT(S) | David J. Legare (Ava, New York) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | David J. Legare (Ava, New York) |
ABSTRACT | A dynamically-reconfigurable antenna having a microstrip patchwork radiating surface wherein individual radiating patches can be connected to and disconnected from each other via photoconductive interconnections between the radiating patches. Commands from software alternately turn light from light emitting sources on or off, the light or lack thereof being channeled from an underside layer of the antenna so as to enable or disable the photoconductive interconnections. The resultant connection or disconnection of the radiating patches will vary the antenna's frequency, bandwidth, and beam pointing. |
FILED | Tuesday, January 24, 2012 |
APPL NO | 13/385469 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Radio wave antennas 343/906 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605081 | Holler et al. |
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FUNDED BY |
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APPLICANT(S) | Wesley A. Holler (Austin, Texas); Gary Anthony McElroy, Jr. (Austin, Texas); Michael E. Weiblen (Black Hawk, Colorado); Thomas Lawrence Burnett, III (Austin, Texas); Mark E. Lucente (Austin, Texas) |
ASSIGNEE(S) | Zebra Imaging, Inc. (Austin, Texas) |
INVENTOR(S) | Wesley A. Holler (Austin, Texas); Gary Anthony McElroy, Jr. (Austin, Texas); Michael E. Weiblen (Black Hawk, Colorado); Thomas Lawrence Burnett, III (Austin, Texas); Mark E. Lucente (Austin, Texas) |
ABSTRACT | Methods and systems for rendering hogels, including notifying one or more rendering nodes that all rendering is complete in response to determining that each of the one or more rendering nodes completes rendering of corresponding one or more subsets of hogel data from 3D data, the rendering nodes being configured to convert the 3D data to the one or more subsets of hogel data. |
FILED | Monday, August 24, 2009 |
APPL NO | 12/546049 |
ART UNIT | 2628 — Selective Visual Display Systems |
CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605108 | Debevec et al. |
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FUNDED BY |
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APPLICANT(S) | Paul E. Debevec (Marina Del Rey, California); Timothy S. Hawkins (Marina Del Rey, California); Chris D. X. N. Tchou (Kirkland, Washington) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Paul E. Debevec (Marina Del Rey, California); Timothy S. Hawkins (Marina Del Rey, California); Chris D. X. N. Tchou (Kirkland, Washington) |
ABSTRACT | A high dynamic range image editing system for editing an image file having pixels spanning a first range of light intensity levels in an image editing system that only displays differences in the light intensity levels of pixels within a second range of light intensity levels that is less than the first range of light intensity levels, without reducing the range of light intensity levels in the image file. |
FILED | Monday, June 13, 2011 |
APPL NO | 13/159156 |
ART UNIT | 2679 — Selective Visual Display Systems |
CURRENT CPC | Computer graphics processing and selective visual display systems 345/589 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605349 | Maraviglia et al. |
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FUNDED BY |
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APPLICANT(S) | Carlos G. Maraviglia (Bethesda, Maryland); Michael Michelizzi (Fort Washington, Maryland); Kevin Cox (Pomfret, Maryland); Thomas Geiger (Huntingtown, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Carlos G. Maraviglia (Bethesda, Maryland); Michael Michelizzi (Fort Washington, Maryland); Kevin Cox (Pomfret, Maryland); Thomas Geiger (Huntingtown, Maryland) |
ABSTRACT | An optical scanning system includes a frame having a central axis along which is mounted a first elevation mirror for receiving an incident light and reflecting the incident light along a first optical path, a telescope for receiving the reflected incident light and outputting an output light, a visible linear array imager for receiving the output light from the telescope, and a folding mirror positioned to receive part of the output light from the telescope and directing it to a linear array infrared imager. The optical scanning system scans large areas of sky using multiple linear sensors in order to detect, identify and track low and slow flying manned and unmanned aircraft as well as to surveil large areas of terrain. |
FILED | Wednesday, September 21, 2011 |
APPL NO | 13/238635 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/212.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605351 | Wang |
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FUNDED BY |
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APPLICANT(S) | Andrew Wang (San Diego, California) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Andrew Wang (San Diego, California) |
ABSTRACT | The visible spectrum modulator makes use of thin film conductive oxides and air gaps to reflect colors of certain wavelengths, achieving transparency due to the transparent nature of conductive oxides and via electrostatic pull-in to reduce the air gaps. |
FILED | Wednesday, June 27, 2012 |
APPL NO | 13/534049 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical: Systems and elements 359/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605355 | Lundquist et al. |
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FUNDED BY |
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APPLICANT(S) | Paul B. Lundquist (Vail, Arizona); Samvel Sarkisyan (Tucson, Arizona); Eric A. Wilson (Tucson, Arizona); Raymond M. Copenhaver (Tucson, Arizona); Hector Martin (Oro Valley, Arizona); Steven McCahon (Tucson, Arizona) |
ASSIGNEE(S) | Applied Energetics (Tucson, Arizona) |
INVENTOR(S) | Paul B. Lundquist (Vail, Arizona); Samvel Sarkisyan (Tucson, Arizona); Eric A. Wilson (Tucson, Arizona); Raymond M. Copenhaver (Tucson, Arizona); Hector Martin (Oro Valley, Arizona); Steven McCahon (Tucson, Arizona) |
ABSTRACT | Presented herein is a multipass optical amplifier including a thin-disk gain medium, a first reflective element optically coupled to the gain medium, a first parabolic reflector in optical communication with the gain medium and the first reflective element, a second parabolic reflector in optical communication with the first parabolic reflector, and a second reflective element in optical communication with the second parabolic reflector. The amplifier also includes a pump source, a signal beam source, and a chamber having first and second regions configured about the multipass optical amplifier with a port that extracts gas from the chamber. The first region includes the first parabolic reflector, the gain medium, and the first reflective element. The second region of the chamber includes the second reflective element and the second parabolic reflector. An input optic propagates the signal beam through the amplifier to impinge the gain medium multiple times for gain. |
FILED | Wednesday, November 24, 2010 |
APPL NO | 12/954387 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Optical: Systems and elements 359/333 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605549 | DiCecco |
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FUNDED BY |
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APPLICANT(S) | John DiCecco (Wakefield, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | John DiCecco (Wakefield, Rhode Island) |
ABSTRACT | Creating a georeference model from input bathymetric data includes defining a search limit grid and establishing a geometric model. An iterative RANSAC process is used to fit bathymetric data calculate the geometric model for each cell of the grid. Points that are too far away from the geometric model are removed, and geometric models are recalculated. The compiled geometric models are used as the georeference model. In further embodiments, the georeference model can be smoothed to remove boundaries between cells. Other embodiments provide for using the georeference model for navigation and data transmission. |
FILED | Wednesday, May 23, 2012 |
APPL NO | 13/478709 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/88 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605703 | Pratt et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas G. Pratt (Covington, Georgia); Brett T. Walkenhorst (Douglasville, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Thomas G. Pratt (Covington, Georgia); Brett T. Walkenhorst (Douglasville, Georgia) |
ABSTRACT | A method for mitigating interference for a received wireless signal comprises at least three steps. The method comprises receiving a wireless signal with a receiver device. The wireless signal includes at least an interference signal and a desired signal. The method further comprises breaking the received wireless signal into sub-bands; and filtering the received wireless signal with a polarization filter, in order to separate the interference signal from the desired signal. |
FILED | Wednesday, January 30, 2008 |
APPL NO | 12/525297 |
ART UNIT | 2478 — Multiplex and VoIP |
CURRENT CPC | Multiplex communications 370/342 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605853 | Schultz et al. |
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FUNDED BY |
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APPLICANT(S) | Kenneth I. Schultz (Lexington, Massachusetts); Brian Tyrrell (Brookline, New Hampshire); Michael W. Kelly (North Reading, Massachusetts); Curtis Colonero (Shrewsbury, Massachusetts); Lawrence M. Candell (Arlington, Massachusetts); Daniel Mooney (Dracut, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Kenneth I. Schultz (Lexington, Massachusetts); Brian Tyrrell (Brookline, New Hampshire); Michael W. Kelly (North Reading, Massachusetts); Curtis Colonero (Shrewsbury, Massachusetts); Lawrence M. Candell (Arlington, Massachusetts); Daniel Mooney (Dracut, Massachusetts) |
ABSTRACT | Digital focal plane arrays (DFPAs) with multiple counters per unit cell can be used to convert analog signals to digital data and to filter the digital data. Exemplary DFPAs include two-dimensional arrays of unit cells, where each unit cell is coupled to a corresponding photodetector in a photodetector array. Each unit cell converts photocurrent from its photodetector to a digital pulse train that is coupled to multiple counters in the unit cell. Each counter in each unit cell can be independently controlled to filter the pulse train by counting up or down and/or by transferring data as desired. For example, a unit cell may perform in-phase/quadrature filtering of homodyne- or heterodyne-detected photocurrent with two counters: a first counter toggled between increment and decrement modes with an in-phase signal and a second counter toggled between increment and decrement modes with a quadrature signal. |
FILED | Thursday, September 08, 2011 |
APPL NO | 13/228367 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Electrical pulse counters, pulse dividers, or shift registers: Circuits and systems 377/118 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606055 | Lipson et al. |
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FUNDED BY |
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APPLICANT(S) | Michal Lipson (Ithaca, New York); Sasikanth Manipatruni (Niskayuna, New York); Hugo Leonardo Rocha de Lira (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Michal Lipson (Ithaca, New York); Sasikanth Manipatruni (Niskayuna, New York); Hugo Leonardo Rocha de Lira (Ithaca, New York) |
ABSTRACT | An optical switch structure and a method for fabricating the optical switch structure provide at least two ring waveguides located and formed supported over a substrate. At least one of the at least two ring waveguides includes at least one PIN diode integral with the ring waveguide as a tuning component for an optical switch device that derives from the optical switch structure. The PIN diode includes different doped silicon slab regions internal to and external to the ring waveguide, and an intrinsic region there between that includes the ring waveguide. The method uses two photolithographic process steps, and also preferably a silicon-on-insulator substrate, to provide the ring waveguides formed of a monocrystalline silicon semiconductor material. |
FILED | Thursday, November 04, 2010 |
APPL NO | 12/939482 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606113 | Koka et al. |
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FUNDED BY |
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APPLICANT(S) | Pranay Koka (Austin, Texas); Michael O. McCracken (Austin, Texas); Herbert D. Schwetman, Jr. (Austin, Texas); Xuexhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
ASSIGNEE(S) | Oracle International Corporation (Redwood Shores, California) |
INVENTOR(S) | Pranay Koka (Austin, Texas); Michael O. McCracken (Austin, Texas); Herbert D. Schwetman, Jr. (Austin, Texas); Xuexhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
ABSTRACT | In a multi-chip module (MCM), integrated circuits are coupled by optical waveguides. These integrated circuits receive optical signals from a set of tunable light sources. Moreover, a given integrated circuit includes: a transmitter that modulates at least one of the optical signals when transmitting information to at least another of the integrated circuits; and a receiver that receives at least one modulated optical signal having a given carrier wavelength associated with the given integrated circuit when receiving information from at least the other of the integrated circuits. Furthermore, control logic in the MCM provides a control signal to the set of tunable light sources to specify carrier wavelengths in the optical signals output by the set of tunable light sources, thereby defining routing of at least the one of the optical signals in the MCM during communication between at least a pair of the integrated circuits. |
FILED | Monday, July 11, 2011 |
APPL NO | 13/180340 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Transmission H04B 10/801 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606346 | Parel et al. |
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FUNDED BY |
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APPLICANT(S) | Jean-Marie Parel (Miami Shores, Florida); Fabrice Manns (Coral Gables, Florida); David S. Robinson (Kansas City, Missouri); Peter Milne (Miami, Florida); David B. Denham (Miami, Florida); Xochitl Gonzalez-Cirre (Madrid, Spain) |
ASSIGNEE(S) | University of Miami (Miami, Florida) |
INVENTOR(S) | Jean-Marie Parel (Miami Shores, Florida); Fabrice Manns (Coral Gables, Florida); David S. Robinson (Kansas City, Missouri); Peter Milne (Miami, Florida); David B. Denham (Miami, Florida); Xochitl Gonzalez-Cirre (Madrid, Spain) |
ABSTRACT | A method of thermally inducing and monitoring changes to localized regions of tissue by illuminating a volume of tissue with a first beam of X-rays, detecting portions of the first beam that passed through the volume, generating a first image signal from the portions of the first beam detected, applying heat to at least a localized region of tissue within the volume after the illuminating and detecting, illuminating the volume with a second beam of X-rays, detecting portions of the second beam that passed through the volume during the illuminating with the second beam, generating a second image signal from the portions of the second beam detected, and generating a difference image signal based upon a comparison of the first and second image signals. The difference image signal provides information of changes in X-ray attenuation by localized regions of tissue within the volume due to the application of heat. |
FILED | Friday, November 04, 2011 |
APPL NO | 13/289709 |
ART UNIT | 3777 — Digital Communications |
CURRENT CPC | Surgery 6/407 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606372 | Harris et al. |
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FUNDED BY |
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APPLICANT(S) | Robert J. Harris (Haslet, Texas); Christopher D. Pylant (Arlington, Texas); Christopher M. Stimek (Fort Worth, Texas); Peter C Gardner (Fort Worth, Texas); Matthew C Ragsdale (Arlington, Texas) |
ASSIGNEE(S) | Williams Pyro, Inc. (Fort Worth, Texas) |
INVENTOR(S) | Robert J. Harris (Haslet, Texas); Christopher D. Pylant (Arlington, Texas); Christopher M. Stimek (Fort Worth, Texas); Peter C Gardner (Fort Worth, Texas); Matthew C Ragsdale (Arlington, Texas) |
ABSTRACT | A system and method of dynamic distributed control with network topology discovery and load discovery in an isolated distribution grid is provided. Source modules connect to AC generators and output high voltage DC power on ports. Load modules receive the high voltage DC power on connected ports and convert the DC power to AC power. Loads are connected to AC outlets on load modules. A source module discovers the connected network topology through a series of states following the reading of a configuration file and creates an adjacency map. Each module has a microprocessor. Each microprocessor runs load discovery algorithms using its adjacency map as input. Load changes are detected and adjacency maps are amended to maintain consistency across all adjacency maps. Priority is afforded to desired loads when demand exceeds capacity. |
FILED | Friday, April 15, 2011 |
APPL NO | 13/088093 |
ART UNIT | 2121 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Generic control systems or specific applications 7/7 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606541 | Platt et al. |
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FUNDED BY |
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APPLICANT(S) | Michael J. Platt (Easton, New Hampshire); John J. Jagodnik (Mine Hill, New Jersey) |
ASSIGNEE(S) | Mechanical Solutions, Inc. (Whippany, New Jersey) |
INVENTOR(S) | Michael J. Platt (Easton, New Hampshire); John J. Jagodnik (Mine Hill, New Jersey) |
ABSTRACT | A method and apparatus for measuring the vibration of rotating blades, such as turbines, compressors, fans, or pumps, including sensing the return signal from projected energy and/or field changes from a plurality of sensors mounted on the machine housing. One or more of the sensors has a narrow field of measurement and the data is processed to provide the referenced time of arrival of each blade, and therefore the blade tip deflection due to vibration. One or more of the sensors has a wide field of measurement, providing a time history of the approaching and receding blades, and the data is processed to provide frequency content and relative magnitudes of the active mode(s) of blade vibration. By combining the overall tip deflection magnitude with the relative magnitudes of the active modes, the total vibratory stress state of the blade can be determined. |
FILED | Monday, June 07, 2010 |
APPL NO | 12/795124 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606724 | Cheng et al. |
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FUNDED BY |
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APPLICANT(S) | Pau-Chen Cheng (Yorktown Heights, New York); John Andrew Clark (York, United Kingdom); Yow Tzu Lim (York, United Kingdom); Pankaj Rohatgi (New Rochelle, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Pau-Chen Cheng (Yorktown Heights, New York); John Andrew Clark (York, United Kingdom); Yow Tzu Lim (York, United Kingdom); Pankaj Rohatgi (New Rochelle, New York) |
ABSTRACT | A method for constructing a classifier which maps an input vector to one of a plurality of pre-defined classes, the method steps includes receiving a set of training examples as input, wherein each training example is an exemplary input vector belonging to one of the pre-defined classes, learning a plurality of functions, wherein each function maps the exemplary input vectors to a numerical value, and determining a class for the input vector by combining numerical outputs of the functions determined for the input vector. |
FILED | Thursday, November 06, 2008 |
APPL NO | 12/266198 |
ART UNIT | 2122 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Artificial intelligence 76/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606838 | Kenefic et al. |
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FUNDED BY |
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APPLICANT(S) | Richard J. Kenefic (Fort Wayne, Indiana); David W. Shin (Fort Wayne, Indiana); Saad Karim (Cary, North Carolina) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Richard J. Kenefic (Fort Wayne, Indiana); David W. Shin (Fort Wayne, Indiana); Saad Karim (Cary, North Carolina) |
ABSTRACT | Disclosed is an efficient and configurable apparatus and method for sample rate conversion using interpolation. The apparatus and method employ a configuration file to change the conversion coefficients, sampling rate, and interpolation algorithm without having to recompile control software and/or reprogram the controlled device. In some embodiments, the interpolation employs polynomial interpolation, which may include Lagrange interpolation. In some embodiments, the interpolation method is selected to minimize the loop delay in teleoperation applications. |
FILED | Wednesday, November 10, 2010 |
APPL NO | 12/943228 |
ART UNIT | 2193 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08607049 | Clement et al. |
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FUNDED BY |
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APPLICANT(S) | Russel E. Clement (El Cajon, California); Stephen L. Childress (San Diego, California); Sarah M. Lauff (San Diego, California); Anton Yen (San Diego, California); Joel T. Baumbaugh (San Diego, California) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Russel E. Clement (El Cajon, California); Stephen L. Childress (San Diego, California); Sarah M. Lauff (San Diego, California); Anton Yen (San Diego, California); Joel T. Baumbaugh (San Diego, California) |
ABSTRACT | In one embodiment, a wireless bridge for wireless to TCP/IP based communication is provided. The wireless bridge can be with reduced functional devices (RFDs) in a star topology network acting as a network access device (NAD). Another embodiment can be with fully functional devices (FFDs) in a peer-to-peer topology network also capable of operating as a NAD. The network address device includes a processor with memory; a radio frequency transceiver front end communicating with the processor; an antenna coupled to the front end; and a power source providing power to the processor and front end wherein the processor with memory contains computer instructions for executing IEEE 802.15.4 standard compliant operations; transmitting a network access device announcement (NADA) message representative of the initiation of passive network discovery to multiple end devices; determining whether a receiving/designated end device is network compliant; establishing communication with the compliant designated end device; and forwarding the NADA message to the designated end device. |
FILED | Tuesday, August 02, 2011 |
APPL NO | 13/195916 |
ART UNIT | 2436 — Cryptography and Security |
CURRENT CPC | Electrical computers and digital processing systems: Support 713/168 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08607199 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Chulho Kim (Poughkeepsie, New York); Hanhong Xue (Wappingers Falls, New York); Tsai-Yang Jea (Poughkeepsie, New York); Hung Q. Thai (New York, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Chulho Kim (Poughkeepsie, New York); Hanhong Xue (Wappingers Falls, New York); Tsai-Yang Jea (Poughkeepsie, New York); Hung Q. Thai (New York, New York) |
ABSTRACT | A technique for debugging code during runtime includes providing, from an outside process, a trigger to a daemon. In this case, the trigger is associated with a registered callback function. The trigger is then provided, from the daemon, to one or more designated tasks of a job. The registered callback function (that is associated with the trigger) is then executed by the one or more designated tasks. Execution results of the executed registered callback function are then returned (from the one or more designated tasks) to the daemon. |
FILED | Wednesday, December 16, 2009 |
APPL NO | 12/639459 |
ART UNIT | 2192 — Interprocess Communication and Software Development |
CURRENT CPC | Data processing: Software development, installation, and management 717/124 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08607240 | Brandt et al. |
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FUNDED BY |
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APPLICANT(S) | Scott A. Brandt (San Jose, California); Richard A. Golding (San Francisco, California); Theodore M Wong (Mountain View, California) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Scott A. Brandt (San Jose, California); Richard A. Golding (San Francisco, California); Theodore M Wong (Mountain View, California) |
ABSTRACT | A method for implementation within a scheduler for a processor is described. The method includes receiving a plurality of jobs from an earliest deadline first (EDF) schedule, wherein the scheduler implements an EDF scheduling model. The method also includes receiving a separate job from a source other than the EDF schedule. The separate job has a fixed scheduling requirement with a specific execution time. The method also includes determining an amount of available utilization capacity of the processor and inserting the separate job into an execution plan of the processor with the plurality of jobs from the EDF schedule in response to a determination that the available utilization capacity of the processor is sufficient to execute the separate job according to the fixed scheduling requirement associated with the separate job. |
FILED | Friday, August 24, 2012 |
APPL NO | 13/594468 |
ART UNIT | 2195 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 08601878 | Cotrell et al. |
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FUNDED BY |
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APPLICANT(S) | Jason Cotrell (Golden, Colorado); Scott Hughes (Golden, Colorado); Sandy Butterfield (Golden, Colorado); Scott Lambert (Boulder, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Jason Cotrell (Golden, Colorado); Scott Hughes (Golden, Colorado); Sandy Butterfield (Golden, Colorado); Scott Lambert (Boulder, Colorado) |
ABSTRACT | A system (1100) for fatigue testing wind turbine blades (1102) through forced or resonant excitation of the base (1104) of a blade (1102). The system (1100) includes a test stand (1112) and a restoring spring assembly (1120) mounted on the test stand (1112). The restoring spring assembly (1120) includes a primary spring element (1124) that extends outward from the test stand (1112) to a blade mounting plate (1130) configured to receive a base (1104) of blade (1102). During fatigue testing, a supported base (1104) of a blade (1102) may be pivotally mounted to the test stand (1112) via the restoring spring assembly (1120). The system (1100) may include an excitation input assembly (1140) that is interconnected with the blade mounting plate (1130) to selectively apply flapwise, edgewise, and/or pitch excitation forces. The restoring spring assembly (1120) may include at least one tuning spring member (1127) positioned adjacent to the primary spring element (1124) used to tune the spring constant or stiffness of the primary spring element (1124) in one of the excitation directions. |
FILED | Friday, May 01, 2009 |
APPL NO | 12/990069 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Wind Motors F03D 11/045 (20130101) F03D 11/0091 (20130101) Original (OR) Class Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2250/42 (20130101) F05B 2260/83 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/06 (20130101) G01M 7/027 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/02 (20130101) G01N 3/32 (20130101) G01N 2203/0035 (20130101) G01N 2203/0073 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08602002 | Brennan |
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FUNDED BY |
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APPLICANT(S) | Daniel G. Brennan (Brighton, Michigan) |
ASSIGNEE(S) | GM Global Technology Operations LLC (, None) |
INVENTOR(S) | Daniel G. Brennan (Brighton, Michigan) |
ABSTRACT | A control system for an engine includes a knock control module and a valve control module. The knock control module adjusts a period that one or more of an intake valve and an exhaust valve of a cylinder are open based on engine knock corresponding to the cylinder. The valve control module, based on the adjusted period, controls the one or more of the intake valve and the exhaust valve using one or more hydraulic actuators. |
FILED | Thursday, August 05, 2010 |
APPL NO | 12/850930 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Internal-combustion engines 123/435 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08602007 | Wu |
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FUNDED BY |
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APPLICANT(S) | Ko-Jen Wu (Troy, Michigan) |
ASSIGNEE(S) | Gm Global Technology Operations LLC (Detroit, Michigan) |
INVENTOR(S) | Ko-Jen Wu (Troy, Michigan) |
ABSTRACT | An intake system for an internal combustion engine comprises an exhaust driven turbocharger configured to deliver compressed intake charge, comprising exhaust gas from the exhaust system and ambient air, through an intake charge conduit and to cylinders of the internal combustion engine. An intake charge cooler is in fluid communication with the intake charge conduit. A cooling system, independent of the cooling system for the internal combustion engine, is in fluid communication with the intake charge cooler through a cooling system conduit. A coolant pump delivers a low temperature cooling medium from the cooling system to and through the intake charge cooler for the transfer of heat from the compressed intake charge thereto. A low temperature cooler receives the heated cooling medium through the cooling system conduit for the transfer of heat therefrom. |
FILED | Friday, September 17, 2010 |
APPL NO | 12/884686 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Internal-combustion engines 123/568.120 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08602084 | Hayes et al. |
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FUNDED BY |
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APPLICANT(S) | Joel Ryan Hayes (Chandler, Arizona); Gregory Walker Nyce (Pleasanton, California); Jushua David Kuntz (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Joel Ryan Hayes (Chandler, Arizona); Gregory Walker Nyce (Pleasanton, California); Jushua David Kuntz (Livermore, California) |
ABSTRACT | A method of producing nanoporous material includes the steps of providing a liquid, providing nanoparticles, producing a slurry of the liquid and the nanoparticles, removing the liquid from the slurry, and producing monolith. |
FILED | Thursday, June 14, 2012 |
APPL NO | 13/523695 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Metal founding 164/97 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08602607 | Arik et al. |
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FUNDED BY |
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APPLICANT(S) | Mehmet Arik (Niskayuna, New York); Stanton Earl Weaver (Niskayuna, New York); Glenn Howard Kuenzler (East Cleveland, Ohio); Charles Franklin Wolfe, Jr. (Niskayuna, New York); Rajdeep Sharma (Clifton Park, New York) |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Mehmet Arik (Niskayuna, New York); Stanton Earl Weaver (Niskayuna, New York); Glenn Howard Kuenzler (East Cleveland, Ohio); Charles Franklin Wolfe, Jr. (Niskayuna, New York); Rajdeep Sharma (Clifton Park, New York) |
ABSTRACT | Lighting systems having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system includes a plurality of synthetic jets. The synthetic jets are arranged within the lighting system such that they are secured at contact points. |
FILED | Thursday, October 21, 2010 |
APPL NO | 12/908948 |
ART UNIT | 2885 — Optics |
CURRENT CPC | Illumination 362/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08602737 | Garcia-Crespo |
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FUNDED BY |
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APPLICANT(S) | Andres Jose Garcia-Crespo (Greenville, South Carolina) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Andres Jose Garcia-Crespo (Greenville, South Carolina) |
ABSTRACT | A sealing device for sealing a gap between a dovetail of a bucket assembly and a rotor wheel is disclosed. The sealing device includes a cover plate configured to cover the gap and a retention member protruding from the cover plate and configured to engage the dovetail. The sealing device provides a seal against the gap when the bucket assembly is subjected to a centrifugal force. |
FILED | Friday, June 25, 2010 |
APPL NO | 12/823483 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Fluid reaction surfaces 416/204.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603199 | Steele et al. |
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FUNDED BY |
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APPLICANT(S) | Philip H. Steele (Starkville, Mississippi); Charles U. Pittman, Jr. (Starkville, Mississippi); Leonard L. Ingram, Jr. (Starkville, Mississippi); Sanjeev Gajjela (Starkville, Mississippi); Zhijun Zhang (Harbin, China PRC); Priyanka Bhattacharya (Knoxville, Tennessee) |
ASSIGNEE(S) | Mississippi State University (Mississippi State, Mississippi) |
INVENTOR(S) | Philip H. Steele (Starkville, Mississippi); Charles U. Pittman, Jr. (Starkville, Mississippi); Leonard L. Ingram, Jr. (Starkville, Mississippi); Sanjeev Gajjela (Starkville, Mississippi); Zhijun Zhang (Harbin, China PRC); Priyanka Bhattacharya (Knoxville, Tennessee) |
ABSTRACT | This invention relates to a method and device to produce esterified, olefinated/esterified, or thermochemolytic reacted bio-oils as fuels. The olefinated/esterified product may be utilized as a biocrude for input to a refinery, either alone or in combination with petroleum crude oils. The bio-oil esterification reaction is catalyzed by addition of alcohol and acid catalyst. The olefination/esterification reaction is catalyzed by addition of resin acid or other heterogeneous catalyst to catalyze olefins added to previously etherified bio-oil; the olefins and alcohol may also be simultaneously combined and catalyzed by addition of resin acid or other heterogeneous catalyst to produce the olefinated/esterified product. |
FILED | Friday, October 01, 2010 |
APPL NO | 12/896741 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Fuel and related compositions 044/310 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603213 | Anderson et al. |
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FUNDED BY |
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APPLICANT(S) | Iver E. Anderson (Ames, Iowa); Joel Rieken (Ankeny, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Iver E. Anderson (Ames, Iowa); Joel Rieken (Ankeny, Iowa) |
ABSTRACT | A method of making dispersion-strengthened alloy particles involves melting an alloy having a corrosion and/or oxidation resistance-imparting alloying element, a dispersoid-forming element, and a matrix metal wherein the dispersoid-forming element exhibits a greater tendency to react with an introduced reactive species than does the alloying element and wherein one or more atomizing parameters is/are modified to controllably reduce the amount of the reactive species, such as oxygen, introduced into the atomized particles so as to reduce anneal times and improve reaction (conversion) to the desired strengthening dispersoids in the matrix. The atomized alloy particles are solidified as solidified alloy particles or as a solidified deposit of alloy particles. Bodies made from the dispersion strengthened alloy particles, deposit thereof, exhibit enhanced fatigue and creep resistance and reduced wear as well as enhanced corrosion and/or oxidation resistance at high temperatures by virtue of the presence of the corrosion and/or oxidation resistance imparting alloying element in solid solution in the particle alloy matrix. |
FILED | Monday, February 25, 2008 |
APPL NO | 12/072298 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/255 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603435 | Miao et al. |
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FUNDED BY |
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APPLICANT(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Albuquerque, New Mexico) |
ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. The present invention represents a step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
FILED | Monday, January 12, 2009 |
APPL NO | 12/811946 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.690 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603573 | Rappe et al. |
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FUNDED BY |
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APPLICANT(S) | Andrew M. Rappe (Penn Valley, Pennsylvania); Alexie Michelle Kolpak (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Andrew M. Rappe (Penn Valley, Pennsylvania); Alexie Michelle Kolpak (Philadelphia, Pennsylvania) |
ABSTRACT | Disclosed herein are perovskite ferroelectric thin-film. Also disclosed are methods of controlling the properties of ferroelectric thin films. These films can be used in a variety materials and devices, such as catalysts and storage media, respectively. |
FILED | Monday, December 03, 2007 |
APPL NO | 12/517163 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating processes 427/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604002 | Walters et al. |
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FUNDED BY |
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APPLICANT(S) | Kent Walters (Notre Dame, Indiana); John G. Duman (Niles, Michigan); Anthony S. Serianni (Notre Dame, Indiana) |
ASSIGNEE(S) | University of Notre Dame Du Lac (Norte Dame, Indiana) |
INVENTOR(S) | Kent Walters (Notre Dame, Indiana); John G. Duman (Niles, Michigan); Anthony S. Serianni (Notre Dame, Indiana) |
ABSTRACT | The invention provides an antifreeze glycolipid compounds and composition comprising a polysaccharide moiety of Formula I: wherein |
FILED | Thursday, June 23, 2011 |
APPL NO | 13/135065 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604098 | Boydston et al. |
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FUNDED BY |
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APPLICANT(S) | Andrew J. Boydston (Seattle, Washington); Robert H. Grubbs (South Pasadena, California); Chris Daeffler (Pasadena, California); Nebojsa Momcilovic (Vienna, Virginia) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Andrew J. Boydston (Seattle, Washington); Robert H. Grubbs (South Pasadena, California); Chris Daeffler (Pasadena, California); Nebojsa Momcilovic (Vienna, Virginia) |
ABSTRACT | Compositions and methods for adjustable lenses are provided. In some embodiments, the lenses contain a lens matrix material, a masking compound, and a prepolymer. The lens matrix material provides structure to the lens. The masking compound is capable of blocking polymerization or crosslinking of the prepolymer, until photoisomerization of the compound is triggered, and the compound is converted from a first isomer to a second isomer having a different absorption profile. The prepolymer is a composition that can undergo a polymerization or crosslinking reaction upon photoinitiation to alter one or more of the properties of the lenses. |
FILED | Wednesday, July 06, 2011 |
APPL NO | 13/177483 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 522/99 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604276 | Stewart et al. |
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FUNDED BY |
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APPLICANT(S) | C. Neal Stewart (Knoxville, Tennessee); David George James Mann (Knoxville, Tennessee) |
ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | C. Neal Stewart (Knoxville, Tennessee); David George James Mann (Knoxville, Tennessee) |
ABSTRACT | The subject application provides polynucleotides, compositions thereof and methods for regulating gene expression in a plant. Polynucleotides disclosed herein comprise novel sequences for a promoter isolated from Panicum virgatum (switchgrass) that initiates transcription of an operably linked nucleotide sequence. Thus, various embodiments of the invention comprise the nucleotide sequence of SEQ ID NO: 2 or fragments thereof comprising nucleotides 1 to 692 of SEQ ID NO: 2 that are capable of driving the expression of an operably linked nucleic acid sequence. |
FILED | Wednesday, June 09, 2010 |
APPL NO | 12/797248 |
ART UNIT | 1638 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/278 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604423 | Enke et al. |
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FUNDED BY |
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APPLICANT(S) | Christie G. Enke (Placitas, New Mexico); Steven J. Ray (Bloomington, Indiana); Alexander W. Graham (Bloomington, Indiana); Gary M. Hieftje (Bloomington, Indiana); Elise Dennis (Bloomington, Indiana); Charles J. Barinaga (West Richland, Washington); David W. Koppenaal (Richland, Washington) |
ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Christie G. Enke (Placitas, New Mexico); Steven J. Ray (Bloomington, Indiana); Alexander W. Graham (Bloomington, Indiana); Gary M. Hieftje (Bloomington, Indiana); Elise Dennis (Bloomington, Indiana); Charles J. Barinaga (West Richland, Washington); David W. Koppenaal (Richland, Washington) |
ABSTRACT | Novel methods and instrumentation for mass spectrometry are described. Zoom-time of flight mass spectrometry (Zoom-TOF) allows increased mass resolution over a pre-determined specific range of masses. Methods for retrofitting traditional time-of-flight (TOF) and distance of flight (DOF) mass spectrometers are described, as well as novel instruments capable of performing Zoom-TOF analyses. |
FILED | Tuesday, April 05, 2011 |
APPL NO | 13/639257 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/287 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604440 | Frisch et al. |
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FUNDED BY |
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APPLICANT(S) | Henry Frisch (Chicago, Illinois); Jean-Francois Genat (Boulogne-Billancourt, France); Hervé Grabas (Chicago, Illinois); Chien-Min Kao (Wilmette, Illinois); Chin-Tu Chen (Lisle, Illinois); Heejong Kim (Chicago, Illinois); Fukun Tang (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Downers Grove, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Henry Frisch (Chicago, Illinois); Jean-Francois Genat (Boulogne-Billancourt, France); Hervé Grabas (Chicago, Illinois); Chien-Min Kao (Wilmette, Illinois); Chin-Tu Chen (Lisle, Illinois); Heejong Kim (Chicago, Illinois); Fukun Tang (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Downers Grove, Illinois) |
ABSTRACT | Large-area, flat-panel photo-detectors with sub-nanosecond time resolution based on microchannel plates are provided. The large-area, flat-panel photo-detectors enable the economic construction of sampling calorimeters with, for example, enhanced capability to measure local energy deposition, depth-of-interaction, time-of-flight, and/or directionality of showers. In certain embodiments, sub-nanosecond timing resolution supplies correlated position and time measurements over large areas. The use of thin flat-panel viewing radiators on both sides of a radiation-creating medium allows simultaneous measurement of Cherenkov and scintillation radiation in each layer of the calorimeter. The detectors may be used in a variety of applications including, for example, medical imaging, security, and particle and nuclear physics. |
FILED | Wednesday, March 09, 2011 |
APPL NO | 13/044442 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/367 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604441 | Mao et al. |
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FUNDED BY |
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APPLICANT(S) | Samuel S. Mao (Castro Valley, California); Dale L. Perry (Hercules, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Samuel S. Mao (Castro Valley, California); Dale L. Perry (Hercules, California) |
ABSTRACT | Room temperature operating solid state hand held neutron detectors integrate one or more relatively thin layers of a high neutron interaction cross-section element or materials with semiconductor detectors. The high neutron interaction cross-section element (e.g., Gd, B or Li) or materials comprising at least one high neutron interaction cross-section element can be in the form of unstructured layers or micro- or nano-structured arrays. Such architecture provides high efficiency neutron detector devices by capturing substantially more carriers produced from high energy α-particles or γ-photons generated by neutron interaction. |
FILED | Thursday, July 23, 2009 |
APPL NO | 12/999909 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/390.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604580 | Mazur et al. |
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FUNDED BY |
|
APPLICANT(S) | Eric Mazur (Concord, Massachusetts); James Edward Carey (Newton, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Eric Mazur (Concord, Massachusetts); James Edward Carey (Newton, Massachusetts) |
ABSTRACT | In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction with an underlying portion of the substrate. A plurality of electrical contacts allow application of a reverse bias voltage to the junction in order to facilitate generation of an electrical signal, e.g., a photocurrent, in response to irradiation of the surface layer. The photodetector exhibits a responsivity greater than about 1 A/W for incident wavelengths in a range of about 250 nm to about 1050 nm, and a responsivity greater than about 0.1 A/W for longer wavelengths, e.g., up to about 3.5 microns. |
FILED | Thursday, October 06, 2011 |
APPL NO | 13/267618 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/436 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604641 | Walker |
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FUNDED BY |
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APPLICANT(S) | Howard Andrew Walker (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Howard Andrew Walker (Golden, Colorado) |
ABSTRACT | A system, method and/or apparatus for the delivery of energy at a site, at least a portion of the energy being delivered by at least one or more of a plurality of renewable energy technologies, the system and method including calculating the load required by the site for the period; calculating the amount of renewable energy for the period, including obtaining a capacity and a percentage of the period for the renewable energy to be delivered; comparing the total load to the renewable energy available; and, implementing one or both of additional and alternative renewable energy sources for delivery of energy to the site. |
FILED | Friday, February 13, 2009 |
APPL NO | 12/808510 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electrical transmission or interconnection systems 37/72 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605438 | Koplow |
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FUNDED BY |
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APPLICANT(S) | Jeffrey P. Koplow (San Ramon, California) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Jeffrey P. Koplow (San Ramon, California) |
ABSTRACT | Systems and methods for a forced-convection heat exchanger are provided. In one embodiment, heat is transferred to or from a thermal load in thermal contact with a heat conducting structure, across a narrow air gap, to a rotating heat transfer structure immersed in a surrounding medium such as air. |
FILED | Friday, August 13, 2010 |
APPL NO | 12/856440 |
ART UNIT | 2835 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/707 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606091 | John et al. |
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FUNDED BY |
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APPLICANT(S) | Randy Carl John (Houston, Texas); Harold J. Vinegar (Bellaire, Texas) |
ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
INVENTOR(S) | Randy Carl John (Houston, Texas); Harold J. Vinegar (Bellaire, Texas) |
ABSTRACT | A system for heating a hydrocarbon containing formation includes a heater having an elongated ferromagnetic metal heater section. The heater is located in an opening in a formation. The heater section is configured to heat the hydrocarbon containing formation. The exposed ferromagnetic metal has a sulfidation rate that goes down with increasing temperature of the heater, when the heater is in a selected temperature range. |
FILED | Friday, October 20, 2006 |
APPL NO | 11/584801 |
ART UNIT | 3742 — Optics |
CURRENT CPC | Electric resistance heating devices 392/301 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 08602999 | Young et al. |
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FUNDED BY |
|
APPLICANT(S) | Darrin J. Young (Salt Lake City, Utah); Wen H. Ko (Cleveland Heights, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Darrin J. Young (Salt Lake City, Utah); Wen H. Ko (Cleveland Heights, Ohio) |
ABSTRACT | An implantable flat blood pressure sensing cuff structure and an implantable blood pressure monitoring device use a first portion of the cuff structure that comprises a sidewall that extends from a surface and contains a pressure sensor, and a second portion of the cuff structure that is configured to overlie and be removably relative to the first portion. The first and second portions of the cuff structure are configured to provide an aperture extending transversely through the cuff structure for receiving a blood vessel therein generally sandwiched between the first portion and the second portion when the second portion is positioned on the first portion such that the pressure sensor is operative to detect vessel expansion and contraction. |
FILED | Thursday, September 16, 2010 |
APPL NO | 12/884037 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603254 | Bagwell et al. |
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FUNDED BY |
|
APPLICANT(S) | Roger B. Bagwell (Bellefonte, Pennsylvania); Paul L. Frankhouser (Miami Beach, Florida); Maureen L. Mulvihill (Bellefonte, Pennsylvania); Josue R. Crespo (Cabo Rojo, Puerto Rico); Brian M. Park (Bellefonte, Pennsylvania); Dana B. Mallen (Yardley, Pennsylvania); Gabriela Hernandez Meza (Philadelphia, Pennsylvania); Debora L. Demers (State College, Pennsylvania) |
ASSIGNEE(S) | Actuated Medical, Inc. (Bellefonte, Pennsylvania) |
INVENTOR(S) | Roger B. Bagwell (Bellefonte, Pennsylvania); Paul L. Frankhouser (Miami Beach, Florida); Maureen L. Mulvihill (Bellefonte, Pennsylvania); Josue R. Crespo (Cabo Rojo, Puerto Rico); Brian M. Park (Bellefonte, Pennsylvania); Dana B. Mallen (Yardley, Pennsylvania); Gabriela Hernandez Meza (Philadelphia, Pennsylvania); Debora L. Demers (State College, Pennsylvania) |
ABSTRACT | A method for the in situ clearing of blockages in artificial tubes completely or partially disposed within a living being is described. The method includes coupling a first end of a releasably-securable flexible clearing member to a controller, inserting a second working end of the flexible clearing member into an opening in the artificial tube, energizing the controller such that said flexible clearing member experiences repetitive motion, and positioning the flexible clearing member such that the second working end of the flexible clearing member comes into repetitive contact with the blockage for clearing the blockage therein. The controller remains outside of the living being and the flexible clearing member clears the blockage when positioned within a straight portion or within a curved portion of the artificial tube. |
FILED | Thursday, August 09, 2012 |
APPL NO | 13/571127 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Cleaning and liquid contact with solids 134/8 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603326 | Painter et al. |
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FUNDED BY |
|
APPLICANT(S) | Paul Painter (Boalsburg, Pennsylvania); Phil Williams (State College, Pennsylvania); Ehren Mannebach (Fond du Lac, Wisconsin); Aron Lupinsky (State College, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Paul Painter (Boalsburg, Pennsylvania); Phil Williams (State College, Pennsylvania); Ehren Mannebach (Fond du Lac, Wisconsin); Aron Lupinsky (State College, Pennsylvania) |
ABSTRACT | Systems, methods and compositions for the separation and recovery of hydrocarbons from particulate matter are herein disclosed. According to one embodiment, a method includes contacting particulate matter with at least one ionic liquid. The particulate matter contains at least one hydrocarbon and at least one solid particulate. When the particulate matter is contacted with the ionic liquid, the hydrocarbon dissociates from the solid particulate to form a multiphase system. |
FILED | Wednesday, August 11, 2010 |
APPL NO | 12/854553 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Mineral oils: Processes and products 28/390 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603327 | Painter et al. |
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FUNDED BY |
|
APPLICANT(S) | Paul Painter (Boalsburg, Pennsylvania); Phil Williams (State College, Pennsylvania); Ehren Mannebach (Fond du Lac, Wisconsin); Aron Lupinsky (State College, Pennsylvania) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Paul Painter (Boalsburg, Pennsylvania); Phil Williams (State College, Pennsylvania); Ehren Mannebach (Fond du Lac, Wisconsin); Aron Lupinsky (State College, Pennsylvania) |
ABSTRACT | Systems, methods and compositions for the separation and recovery of hydrocarbons from particulate matter are herein disclosed. According to one embodiment, a method includes contacting particulate matter with at least one analogue ionic liquid. The particulate matter contains at least one hydrocarbon and at least one solid particulate. When the particulate matter is contacted with the analogue ionic liquid, the hydrocarbon dissociates from the solid particulate to form a multiphase system. |
FILED | Tuesday, October 04, 2011 |
APPL NO | 13/252523 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Mineral oils: Processes and products 28/390 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603573 | Rappe et al. |
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FUNDED BY |
|
APPLICANT(S) | Andrew M. Rappe (Penn Valley, Pennsylvania); Alexie Michelle Kolpak (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Andrew M. Rappe (Penn Valley, Pennsylvania); Alexie Michelle Kolpak (Philadelphia, Pennsylvania) |
ABSTRACT | Disclosed herein are perovskite ferroelectric thin-film. Also disclosed are methods of controlling the properties of ferroelectric thin films. These films can be used in a variety materials and devices, such as catalysts and storage media, respectively. |
FILED | Monday, December 03, 2007 |
APPL NO | 12/517163 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating processes 427/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603662 | Sastry et al. |
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FUNDED BY |
|
APPLICANT(S) | Ann Marie Sastry (Ann Arbor, Michigan); Fabio Albano (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Ann Marie Sastry (Ann Arbor, Michigan); Fabio Albano (Ann Arbor, Michigan) |
ABSTRACT | A battery includes a first portion including a substrate having formed thereon a current collector and an anode electrode material. A second portion is formed on a substrate and includes a current collector and a cathode electrode material. The first portion is joined to the second portion and a separator is disposed between the first portion and the second portion as joined to separate the anode electrode material from the cathode electrode material. An electrolyte is placed in contact with the anode electrode material, the cathode electrode material and the separator. |
FILED | Wednesday, June 20, 2012 |
APPL NO | 13/528055 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/129 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603705 | Aiyar et al. |
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FUNDED BY |
|
APPLICANT(S) | Avishek Aiyar (Atlanta, Georgia); Rakesh Nambiar (Wilmington, Delaware); David Collard (Atlanta, Georgia); Elsa Reichmanis (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Avishek Aiyar (Atlanta, Georgia); Rakesh Nambiar (Wilmington, Delaware); David Collard (Atlanta, Georgia); Elsa Reichmanis (Atlanta, Georgia) |
ABSTRACT | Described herein are improved methods of forming polymer films, the polymer films formed thereby, and electronic devices formed form the polymer films. The methods generally include contacting a polymer with a solvent to at least partially solvate the polymer in the solvent, exposing the at least partially solvated polymer and solvent to ultrasonic energy for a duration effective to form a plurality of ordered assemblies of the polymer in the solvent, and forming a solid film of the polymer, wherein the solid film comprises the plurality of ordered assemblies of the polymer. |
FILED | Thursday, March 31, 2011 |
APPL NO | 13/077896 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603832 | Whitesides et al. |
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FUNDED BY |
|
APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Whitesides (Newton, Massachusetts); Scott T. Phillips (Cambridge, Massachusetts); Andreas W. Martinez (Cambridge, Massachusetts); Manish J. Butte (Boston, Massachusetts); Amy Wong (Saratoga, California); Samuel W. Thomas (Boston, Massachusetts); Hayat Sindi (Cambridge, United Kingdom); Sarah J. Vella (Ontario, Canada); Emanuel Carrilho (Chestnut Hill, Massachusetts); Katherine A. Mirica (Waltham, Massachusetts); Yanyan Liu (Cambridge, Massachusetts) |
ABSTRACT | Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region. |
FILED | Friday, December 28, 2012 |
APPL NO | 13/730028 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/169 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603945 | Knoth et al. |
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FUNDED BY |
|
APPLICANT(S) | Colleen Marie Knoth (Costa Mesa, California); Thomas Eulgem (Riverside, California); Thomas Girke (Riverside, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Colleen Marie Knoth (Costa Mesa, California); Thomas Eulgem (Riverside, California); Thomas Girke (Riverside, California) |
ABSTRACT | This disclosure relates to methods and compositions for modulating disease resistance in plants and transgenic plants. |
FILED | Thursday, July 23, 2009 |
APPL NO | 13/055363 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Plant protecting and regulating compositions 54/100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604002 | Walters et al. |
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FUNDED BY |
|
APPLICANT(S) | Kent Walters (Notre Dame, Indiana); John G. Duman (Niles, Michigan); Anthony S. Serianni (Notre Dame, Indiana) |
ASSIGNEE(S) | University of Notre Dame Du Lac (Norte Dame, Indiana) |
INVENTOR(S) | Kent Walters (Notre Dame, Indiana); John G. Duman (Niles, Michigan); Anthony S. Serianni (Notre Dame, Indiana) |
ABSTRACT | The invention provides an antifreeze glycolipid compounds and composition comprising a polysaccharide moiety of Formula I: wherein |
FILED | Thursday, June 23, 2011 |
APPL NO | 13/135065 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604141 | Grubbs et al. |
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FUNDED BY |
|
APPLICANT(S) | Robert H. Grubbs (S. Pasadena, California); Peter Schwab (East Hanover, New Jersey); Sonbinh T. Nguyen (Evanston, Illinois) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Robert H. Grubbs (S. Pasadena, California); Peter Schwab (East Hanover, New Jersey); Sonbinh T. Nguyen (Evanston, Illinois) |
ABSTRACT | Ruthenium and osmium carbene compounds that are stable in the presence of a variety of functional groups and can be used to catalyze olefin metathesis reactions on unstrained cyclic and acyclic olefins are disclosed. Also disclosed are methods of making the carbene compounds. The carbene compounds are of the formula where M is Os or Ru; R1 is hydrogen; R is selected from the group consisting of hydrogen, substituted or unsubstituted alkyl, and substituted or unsubstituted aryl; X and X1 are independently selected from any anionic ligand; and L and L1 are independently selected from any neutral electron donor. The ruthenium and osmium carbene compounds of the present invention may be synthesized using diazo compounds, by neutral electron donor ligand exchange, by cross metathesis, using acetylene, using cumulated olefins, and in a one-pot method using diazo compounds and neutral electron donors. The ruthenium and osmium carbene compounds of the present invention may be used to catalyze olefin metathesis reactions including, but not limited to, ROMP, RCM, depolymerization of unsaturated polymers, synthesis of telechelic polymers, and olefin synthesis. |
FILED | Tuesday, April 24, 2012 |
APPL NO | 13/454244 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Synthetic resins or natural rubbers 526/92 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604213 | Dimagno |
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FUNDED BY |
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APPLICANT(S) | Stephen Dimagno (Lincoln, Nebraska) |
ASSIGNEE(S) | Nutech Ventures (Lincoln, Nebraska) |
INVENTOR(S) | Stephen Dimagno (Lincoln, Nebraska) |
ABSTRACT | This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds. |
FILED | Tuesday, October 20, 2009 |
APPL NO | 13/125209 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/330 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604440 | Frisch et al. |
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FUNDED BY |
|
APPLICANT(S) | Henry Frisch (Chicago, Illinois); Jean-Francois Genat (Boulogne-Billancourt, France); Hervé Grabas (Chicago, Illinois); Chien-Min Kao (Wilmette, Illinois); Chin-Tu Chen (Lisle, Illinois); Heejong Kim (Chicago, Illinois); Fukun Tang (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Downers Grove, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Henry Frisch (Chicago, Illinois); Jean-Francois Genat (Boulogne-Billancourt, France); Hervé Grabas (Chicago, Illinois); Chien-Min Kao (Wilmette, Illinois); Chin-Tu Chen (Lisle, Illinois); Heejong Kim (Chicago, Illinois); Fukun Tang (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Downers Grove, Illinois) |
ABSTRACT | Large-area, flat-panel photo-detectors with sub-nanosecond time resolution based on microchannel plates are provided. The large-area, flat-panel photo-detectors enable the economic construction of sampling calorimeters with, for example, enhanced capability to measure local energy deposition, depth-of-interaction, time-of-flight, and/or directionality of showers. In certain embodiments, sub-nanosecond timing resolution supplies correlated position and time measurements over large areas. The use of thin flat-panel viewing radiators on both sides of a radiation-creating medium allows simultaneous measurement of Cherenkov and scintillation radiation in each layer of the calorimeter. The detectors may be used in a variety of applications including, for example, medical imaging, security, and particle and nuclear physics. |
FILED | Wednesday, March 09, 2011 |
APPL NO | 13/044442 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/367 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605280 | Heck et al. |
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FUNDED BY |
|
APPLICANT(S) | Kimberly Nadia Heck (Houston, Texas); Nancy Jean Halas (Houston, Texas); Michael Sha-Nang Wong (Houston, Texas) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
INVENTOR(S) | Kimberly Nadia Heck (Houston, Texas); Nancy Jean Halas (Houston, Texas); Michael Sha-Nang Wong (Houston, Texas) |
ABSTRACT | The invention relates to a multimetallic nanoshell sensor which comprises a core that is less conductive that a first metallic layer and having a catalytically active second metallic layer partially or completely surrounding the first metallic layer. The sensor can be used in any surface enhanced spectroscopic applications. |
FILED | Thursday, November 06, 2008 |
APPL NO | 12/741586 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/301 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605516 | Moore et al. |
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FUNDED BY |
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APPLICANT(S) | Christopher D. Moore (Pasadena, California); Sean J. Keller (San Diego, California); Alain J. Martin (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Christopher D. Moore (Pasadena, California); Sean J. Keller (San Diego, California); Alain J. Martin (Pasadena, California) |
ABSTRACT | A random access memory (RAM) cell provides a control section and a storage section coupled to the storage section. The storage section includes complementary metal-oxide semiconductor (CMOS) transistors and the storage section is read by precharging the control section to a virtual drain voltage. |
FILED | Thursday, January 07, 2010 |
APPL NO | 12/683989 |
ART UNIT | 2824 — Semiconductors/Memory |
CURRENT CPC | Static information storage and retrieval 365/188 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606055 | Lipson et al. |
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FUNDED BY |
|
APPLICANT(S) | Michal Lipson (Ithaca, New York); Sasikanth Manipatruni (Niskayuna, New York); Hugo Leonardo Rocha de Lira (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Michal Lipson (Ithaca, New York); Sasikanth Manipatruni (Niskayuna, New York); Hugo Leonardo Rocha de Lira (Ithaca, New York) |
ABSTRACT | An optical switch structure and a method for fabricating the optical switch structure provide at least two ring waveguides located and formed supported over a substrate. At least one of the at least two ring waveguides includes at least one PIN diode integral with the ring waveguide as a tuning component for an optical switch device that derives from the optical switch structure. The PIN diode includes different doped silicon slab regions internal to and external to the ring waveguide, and an intrinsic region there between that includes the ring waveguide. The method uses two photolithographic process steps, and also preferably a silicon-on-insulator substrate, to provide the ring waveguides formed of a monocrystalline silicon semiconductor material. |
FILED | Thursday, November 04, 2010 |
APPL NO | 12/939482 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 08603566 | McClements et al. |
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FUNDED BY |
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APPLICANT(S) | David Julian McClements (Northampton, Massachusetts); Eric Andrew Decker (Sunderland, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | David Julian McClements (Northampton, Massachusetts); Eric Andrew Decker (Sunderland, Massachusetts) |
ABSTRACT | The present invention provides stabilized oil-in-water emulsions with an extended range of chemical, thermal and/or mechanical stabilities, and method(s) for their preparation. Such preparations provide an environmentally-protective biopolymer component exhibiting improved adherence to the dispersed phase, reducing or eliminating dissociation therefrom under such conditions, for use in the context of a range of food, pharmaceutical, personal care, health care, cosmetic and other end-use applications. |
FILED | Monday, December 22, 2008 |
APPL NO | 12/809185 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Food or edible material: Processes, compositions, and products 426/601 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603748 | Fratamico et al. |
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FUNDED BY |
|
APPLICANT(S) | Pina Fratamico (Elkins Park, Pennsylvania); Susumu Kawasaki (Tsukuba, Japan); Shinichi Kawamoto (Tsukuba, Japan) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Pina Fratamico (Elkins Park, Pennsylvania); Susumu Kawasaki (Tsukuba, Japan); Shinichi Kawamoto (Tsukuba, Japan) |
ABSTRACT | The phylogeny of twelve Campylobacter species was determined based on partial (1020-bp) gyrB gene sequences. Methods have been described for detection and speciation of Campylobacter, including 16S rRNA sequence analysis. However, gyrB provides a better resolution than the 16S rDNA gene for Campylobacter species with interspecies sequence similarities ranging from 58.3 to 89.2% compared to those reported for the 16S rRNA gene (ranging from 89 to 99%). A universal primer set, designed to amplify a 960-bp fragment of the gyrB gene in Campylobacter spp., was developed and used for (PCR-RFLP) of 19 strains representing twelve Campylobacter species and resulted in unique digest patterns for all twelve Campylobacter species. PCR assays for amplification of regions of the gyrB gene specific for each Campylobacter species were also developed. Using these PCR and PCR-RFLP methods results in unambiguous identification of the majority of Campylobacter species. |
FILED | Friday, February 08, 2008 |
APPL NO | 12/069268 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08604239 | Kim |
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FUNDED BY |
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APPLICANT(S) | Moon Kim (Starkville, Mississippi) |
ASSIGNEE(S) | Mississippi State University Research and Technology Corporation (Mississippi State, Mississippi) |
INVENTOR(S) | Moon Kim (Starkville, Mississippi) |
ABSTRACT | The present invention provides manufacturing of and the use of novel diethylene tricarbamide and its condensation reaction products formed by reacting with formaldehyde as wood composite binder resins and in other applications. These resins have thermosetting capabilities and therefore usefulness as binders for wood and other materials with superior resin properties of low cost, colorlessness, exceptionally good binding, and fast curing characteristics, as well as very low formaldehyde emissions. The synthesized novel starting material for the thermosetting resins of the present invention is diethylene tricarbamide. |
FILED | Friday, April 27, 2012 |
APPL NO | 13/506567 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Organic compounds 564/61 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP24072 | Banuelos et al. |
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FUNDED BY |
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APPLICANT(S) | Gary Banuelos (Fresno, California); John Leonard Freeman (Fresno, California); John Diener (Five Points, California) |
ASSIGNEE(S) | California State University, Fresno (Fresno, California); Red Rock Ranch, LLC (Five Points, California); USDA (Washington, District of Columbia) |
INVENTOR(S) | Gary Banuelos (Fresno, California); John Leonard Freeman (Fresno, California); John Diener (Five Points, California) |
ABSTRACT | A new and distinctly salt and boron tolerant cultivar of prickly pear (Opuntia ficus-indica), named ‘Seleno-Purple,’ is particularly distinguishable by its ability to tolerate and grow in high concentration of salt, boron and selenium-laden soil. The cultigen was originally discovered by stringent selection of randomly harvested cladodes (modified stems) and potentially from isolation of a single unique cladode or sport that exhibited high levels of salt and boron tolerance necessary for survival, and then propagated into the ‘Seleno-Purple’ cultivar. The cladodes were originally randomly harvested from different individual plants and screened from within a naturally segregating wild population or accession. The ‘Seleno-Purple’ cultivar has yellow flowers, mature green cladodes without glochids, and purple fruit. When grown in a saline/selenium-laden soil, the spineless ‘Seleno-Purple’ cultivar absorbs high concentrations of natural-occurring selenium, volatilizes selenium, and produces edible cladodes and fruit enriched with potential anti-carcinogenic forms of organic selenium. |
FILED | Wednesday, March 21, 2012 |
APPL NO | 13/506029 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/156 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP24073 | Cummins et al. |
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FUNDED BY |
|
APPLICANT(S) | James Cummins (Geneva, New York); Herbert Sanders Aldwinckle (Geneva, New York); Terence Lee Robinson (Geneva, New York); Gennaro Fazio (Geneva, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | James Cummins (Geneva, New York); Herbert Sanders Aldwinckle (Geneva, New York); Terence Lee Robinson (Geneva, New York); Gennaro Fazio (Geneva, New York) |
ABSTRACT | A new and distinct variety of apple tree Malus domestica×Malus robusta hybrid ‘G.969’ is described herein. The new variety is resistant to fire blight (Erwinia amylovora) and crown rot (Phytophthora cactorum). The ‘G.969’ rootstock is useful in that it can be propagated clonally and used as a semi-dwarfing rootstock or root system for apple trees as well as for interstems of apple trees. |
FILED | Tuesday, October 19, 2010 |
APPL NO | 12/925309 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/174 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 08603205 | Fedorov et al. |
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FUNDED BY |
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APPLICANT(S) | Andrei G. Fedorov (Atlanta, Georgia); Mark Varaday (Atlanta, Georgia); F. Levent Degertekin (Decatur, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Andrei G. Fedorov (Atlanta, Georgia); Mark Varaday (Atlanta, Georgia); F. Levent Degertekin (Decatur, Georgia) |
ABSTRACT | Fuel processors, methods of using fuel processors, and the like, are disclosed. |
FILED | Tuesday, February 01, 2011 |
APPL NO | 13/018614 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Gas: Heating and illuminating 048/197.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603285 | Baron |
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FUNDED BY |
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APPLICANT(S) | Richard L. Baron (La Crescenta, California) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Richard L. Baron (La Crescenta, California) |
ABSTRACT | Disclosed herein is a method of making a mirror support comprising a composite, the composite comprising a plurality of carbon nanotubes, wherein at least two of the plurality of carbon nanotubes are bonded to each other through a bridging moiety bound to each of the two carbon nanotubes, and a laminate comprising the composite. |
FILED | Friday, March 05, 2010 |
APPL NO | 12/718206 |
ART UNIT | 1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/272.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603400 | Hays et al. |
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FUNDED BY |
|
APPLICANT(S) | Charles C. Hays (Pasadena, California); Sri R. Narayan (Arcadia, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Charles C. Hays (Pasadena, California); Sri R. Narayan (Arcadia, California) |
ABSTRACT | A series of binary and ternary Pt-alloys, that promote the important reactions for catalysis at an alloy surface; oxygen reduction, hydrogen oxidation, and hydrogen and oxygen evolution. The first two of these reactions are essential when applying the alloy for use in a PEMFC. |
FILED | Thursday, May 20, 2010 |
APPL NO | 12/784466 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/170 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08605262 | Campbell et al. |
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FUNDED BY |
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APPLICANT(S) | Joel F. Campbell (Poquoson, Virginia); Narasimha S. Prasad (Yorktown, Virginia); Fenton W. Harrison (Windsor, Virginia); Michael A. Flood (Hampton, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Joel F. Campbell (Poquoson, Virginia); Narasimha S. Prasad (Yorktown, Virginia); Fenton W. Harrison (Windsor, Virginia); Michael A. Flood (Hampton, Virginia) |
ABSTRACT | A continuous wave Light Detection and Ranging (CW LiDAR) system utilizes two or more laser frequencies and time or range shifted pseudorandom noise (PN) codes to discriminate between the laser frequencies. The performance of these codes can be improved by subtracting out the bias before processing. The CW LiDAR system may be mounted to an artificial satellite orbiting the earth, and the relative strength of the return signal for each frequency can be utilized to determine the concentration of selected gases or other substances in the atmosphere. |
FILED | Thursday, June 23, 2011 |
APPL NO | 13/167093 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Optics: Measuring and testing 356/5.90 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606541 | Platt et al. |
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FUNDED BY |
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APPLICANT(S) | Michael J. Platt (Easton, New Hampshire); John J. Jagodnik (Mine Hill, New Jersey) |
ASSIGNEE(S) | Mechanical Solutions, Inc. (Whippany, New Jersey) |
INVENTOR(S) | Michael J. Platt (Easton, New Hampshire); John J. Jagodnik (Mine Hill, New Jersey) |
ABSTRACT | A method and apparatus for measuring the vibration of rotating blades, such as turbines, compressors, fans, or pumps, including sensing the return signal from projected energy and/or field changes from a plurality of sensors mounted on the machine housing. One or more of the sensors has a narrow field of measurement and the data is processed to provide the referenced time of arrival of each blade, and therefore the blade tip deflection due to vibration. One or more of the sensors has a wide field of measurement, providing a time history of the approaching and receding blades, and the data is processed to provide frequency content and relative magnitudes of the active mode(s) of blade vibration. By combining the overall tip deflection magnitude with the relative magnitudes of the active modes, the total vibratory stress state of the blade can be determined. |
FILED | Monday, June 07, 2010 |
APPL NO | 12/795124 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 1/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 08603534 | Zale et al. |
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FUNDED BY |
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APPLICANT(S) | BIND Therapeutics, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | BIND Therapeutics, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Stephen E. Zale (Hopkinton, Massachusetts); Greg Troiano (Pembroke, Massachusetts); Mir Mukkaram Ali (Woburn, Massachusetts); Jeff Hrkach (Lexington, Massachusetts); James Wright (Lexington, Massachusetts) |
ABSTRACT | The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic)acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles. |
FILED | Tuesday, May 28, 2013 |
APPL NO | 13/903249 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/436 (20130101) Acyclic or Carbocyclic Compounds C07C 59/08 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606066 | Delaney et al. |
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FUNDED BY |
|
APPLICANT(S) | mBio Diagnostics, Inc. (Boulder, Colorado) |
ASSIGNEE(S) | MBio Diagnostics, Inc. (Boulder, Colorado) |
INVENTOR(S) | Marie J. Delaney (Boulder, Colorado); Kevin D. Moll (Boulder, Colorado) |
ABSTRACT | An apparatus for illuminating a sample includes a planar waveguide. The planar waveguide includes a first substrate, including a first outer surface and a first inner surface, and a second substrate, including a second outer surface and a second inner surface. The first and second inner surfaces of the first and second substrates, respectively, are spaced apart from each other and partly define a volume for confining the sample therein. The apparatus also includes a light source for providing light directed toward the planar waveguide, such that the light is optically coupled to and contained within the planar waveguide between the outer surfaces of the first and second substrates, while illuminating at least a portion of the sample confined within the volume. |
FILED | Tuesday, December 04, 2012 |
APPL NO | 13/693810 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/129 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08606781 | Chi et al. |
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FUNDED BY |
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APPLICANT(S) | Ed Chi (Palo Alto, California); Fabio Gasparetti (Rome, Italy) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Ed Chi (Palo Alto, California); Fabio Gasparetti (Rome, Italy) |
ABSTRACT | Techniques are presented to provide personalized search results to a user. A user history optionally classified into projects or tasks is determined. A profile for the user is determined by identifying keywords, concepts or other user and/or task specific descriptors within user history documents. A proximal neighborhood based on the user's history and adjustable crawling parameters is determined. The adjustable crawling parameters define which documents linked to documents in the user history are included within the proximal neighborhood. A user query is determined and used to search the set of documents within the proximal neighborhood. The results are then ranked based on the user profile information. The ranked results are optionally displayed to the user. |
FILED | Tuesday, August 09, 2005 |
APPL NO | 11/200557 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/734 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 08603462 | Westenfelder |
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FUNDED BY |
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APPLICANT(S) | Christof Westenfelder (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah); United States of America Department of Veteran's Affairs. (Washington, District of Columbia) |
INVENTOR(S) | Christof Westenfelder (Salt Lake City, Utah) |
ABSTRACT | Methods for the treatment of acute renal failure, multi-organ failure, early dysfunction of kidney transplant, chronic renal failure, organ dysfunction, and wound healing are provided. The methods include delivering a therapeutic amount of hematopoietic stem cells, non-hematopoietic, mesenchymal stem cells, hemangioblasts, and pre-differentiated cells to a patient in need thereof. |
FILED | Wednesday, March 31, 2004 |
APPL NO | 10/551317 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603758 | Acevedo-Duncan et al. |
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FUNDED BY |
|
APPLICANT(S) | Mildred Acevedo-Duncan (Plant City, Florida); Hla Y. Win (Tampa, Florida); Raoul Salup (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Mildred Acevedo-Duncan (Plant City, Florida); Hla Y. Win (Tampa, Florida); Raoul Salup (Tampa, Florida) |
ABSTRACT | A method of detecting prostate tumorigenesis in a subject, the method including the steps of (a) obtaining a sample from the prostate of the human subject, (b) detecting quantitatively or semi-quantitatively in the sample a level of expression for PKC-ι and (c) comparing the expression level in (b) to a level of expression in a normal control, wherein overexpression of PKC-ι, with respect to the control, indicates the presence of prostate cancer in the subject. The present invention is based upon the discovery that PKC-ι levels are elevated during prostate tumorigenesis. Furthermore, the proliferation rate of the tumor correlates with the level of PKC-ι. The invention also provides methods of treating prostate cancer by administering to the subject a compound that inhibits the expression of PKC-ι. The compound can be a small interfering RNA (siRNA) molecule. |
FILED | Monday, June 25, 2012 |
APPL NO | 13/532364 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 08601928 | Martinez et al. |
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FUNDED BY |
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APPLICANT(S) | Martin A. Martinez (Phoenix, Arizona); Patrick Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California) |
ASSIGNEE(S) | Engineering Science Analysis Corp. (Tempe, Arizona) |
INVENTOR(S) | Martin A. Martinez (Phoenix, Arizona); Patrick Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California) |
ABSTRACT | A method and device for impeding the progress of a swimmer or a diver included a plurality of tendrils that can be launched into the path of a target and entangle the target. |
FILED | Tuesday, July 20, 2010 |
APPL NO | 12/839930 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/1.340 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08603736 | Petropoulos |
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FUNDED BY |
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APPLICANT(S) | Christos J. Petropoulos (Half Moon Bay, California) |
ASSIGNEE(S) | Monogram Biosciences, Inc. (South San Francisco, California) |
INVENTOR(S) | Christos J. Petropoulos (Half Moon Bay, California) |
ABSTRACT | The invention provides a method for determining whether a human immunodeficiency virus is resistance to a viral entry inhibitor. The methods are particularly useful for determining resistance to inhibitors that act by a non-competitive mechanism. In certain aspects, the methods comprise determining whether an HIV population is resistant to an HIV entry inhibitor, comprising determining a log-sigmoid inhibition curve comprising data points for entry of the HIV population in the presence of varying concentrations of the HIV entry inhibitor, wherein if the entry of the HIV population cannot be completely inhibited by the HIV entry inhibitor, the HIV population is resistant to the HIV entry inhibitor. |
FILED | Monday, June 06, 2005 |
APPL NO | 11/146879 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 08604446 | Ditto |
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FUNDED BY |
|
APPLICANT(S) | Jeffrey J. Ditto (Eugene, Oregon) |
ASSIGNEE(S) | The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon) |
INVENTOR(S) | Jeffrey J. Ditto (Eugene, Oregon) |
ABSTRACT | Cryogenic manipulation of a material sample with an in situ probe is enabled with a novel cooled probe design. A material sample mounted on a cryo-stage in a vacuum chamber is cooled to a cryogenic temperature. In addition, a nano-manipulator probe inside the sample chamber is also cooled to cryogenic temperature. A specific sample site is milled in the chamber using a focused ion beam and attached to the cooled probe by vapor deposition. After releasing the sample, the sample site is attached to a destination surface such as a transmission electron microscope (TEM) grid and the probe is then detached from the sample using the focused ion beam. |
FILED | Wednesday, August 08, 2012 |
APPL NO | 13/570127 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Radiant energy 250/443.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP24072 | Banuelos et al. |
---|---|
FUNDED BY |
|
APPLICANT(S) | Gary Banuelos (Fresno, California); John Leonard Freeman (Fresno, California); John Diener (Five Points, California) |
ASSIGNEE(S) | California State University, Fresno (Fresno, California); Red Rock Ranch, LLC (Five Points, California); USDA (Washington, District of Columbia) |
INVENTOR(S) | Gary Banuelos (Fresno, California); John Leonard Freeman (Fresno, California); John Diener (Five Points, California) |
ABSTRACT | A new and distinctly salt and boron tolerant cultivar of prickly pear (Opuntia ficus-indica), named ‘Seleno-Purple,’ is particularly distinguishable by its ability to tolerate and grow in high concentration of salt, boron and selenium-laden soil. The cultigen was originally discovered by stringent selection of randomly harvested cladodes (modified stems) and potentially from isolation of a single unique cladode or sport that exhibited high levels of salt and boron tolerance necessary for survival, and then propagated into the ‘Seleno-Purple’ cultivar. The cladodes were originally randomly harvested from different individual plants and screened from within a naturally segregating wild population or accession. The ‘Seleno-Purple’ cultivar has yellow flowers, mature green cladodes without glochids, and purple fruit. When grown in a saline/selenium-laden soil, the spineless ‘Seleno-Purple’ cultivar absorbs high concentrations of natural-occurring selenium, volatilizes selenium, and produces edible cladodes and fruit enriched with potential anti-carcinogenic forms of organic selenium. |
FILED | Wednesday, March 21, 2012 |
APPL NO | 13/506029 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/156 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 08601928 | Martinez et al. |
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FUNDED BY |
|
APPLICANT(S) | Martin A. Martinez (Phoenix, Arizona); Patrick Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California) |
ASSIGNEE(S) | Engineering Science Analysis Corp. (Tempe, Arizona) |
INVENTOR(S) | Martin A. Martinez (Phoenix, Arizona); Patrick Barnhill (Phoenix, Arizona); Steven A. Floyd (Petaluma, California) |
ABSTRACT | A method and device for impeding the progress of a swimmer or a diver included a plurality of tendrils that can be launched into the path of a target and entangle the target. |
FILED | Tuesday, July 20, 2010 |
APPL NO | 12/839930 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/1.340 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 08604965 | Jennings et al. |
---|---|
FUNDED BY |
|
APPLICANT(S) | Richard Earl Jennings (Fredricksburg, Virginia); Thomas Lee Pagano (Egg Harbor Township, New Jersey) |
ASSIGNEE(S) | Federal Aviation Administration/Department of Transportation (Washington, District of Columbia) |
INVENTOR(S) | Richard Earl Jennings (Fredricksburg, Virginia); Thomas Lee Pagano (Egg Harbor Township, New Jersey) |
ABSTRACT | An apparatus and method to generate and detect virtual targets. Position information for one or more virtual targets is calculated onboard a vehicle from real position information obtained from GPS satellites or other external or internal sources. This virtual position information is coded, mixed with a carrier frequency, amplified, and radiated to a nearby test vehicle, such as an aircraft. The amplitude of the radiated signal is adjusted such that the signal containing the virtual position information is received by the test aircraft only. The radiated signal thus adjusted is below the detection threshold of any aircraft further away. The test aircraft decodes the signal and interprets the decoded virtual position information as real aircraft in its vicinity. The coded signals may be structured to comply with the requirements of the FAA's ADS-B system. The apparatus may be mounted on the test aircraft itself, or on a nearby aircraft. |
FILED | Tuesday, February 08, 2011 |
APPL NO | 12/929672 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Communications: Directive radio wave systems and devices 342/37 |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
US 08603080 | Fried et al. |
---|---|
FUNDED BY |
|
APPLICANT(S) | Nathaniel M. Fried (Concord, North Carolina); Christopher M. Cilip (Maple Grove, Minnesota) |
ASSIGNEE(S) | University of North Carolina at Charlotte (Charlotte, North Carolina) |
INVENTOR(S) | Nathaniel M. Fried (Concord, North Carolina); Christopher M. Cilip (Maple Grove, Minnesota) |
ABSTRACT | The present invention presents novel methods for performing noninvasive vasectomies in animals, including humans, and vasectomy clamps for use in such procedures. The invention further presents an apparatus for use in noninvasive male sterilization procedures. More specifically, the invention presents the application of lasers for noninvasive thermal coagulation and occlusion of the vas. Non-contact cooling of the tissue surface, for example, via cryogen or other cooling spray, prevents scrotal skin burns during the procedure. Both the laser radiation and cooling spray are delivered in a non-contact mode to the tissue. This procedure also preserves the surgical field-of-view, potentially allowing the urologist to visually monitor the skin surface during subsurface heating of the vas and preventing the formation of scrotal skin burns. |
FILED | Monday, July 29, 2013 |
APPL NO | 13/952955 |
ART UNIT | 3769 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 66/10 |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 08605954 | Zimmerman |
---|---|
FUNDED BY |
|
APPLICANT(S) | Robert S. Zimmerman (South Riding, Virginia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Robert S. Zimmerman (South Riding, Virginia) |
ABSTRACT | Methods and systems for evaluating an imager that produces bi-chrome images from a scanner or a digital imaging device. The bi-chrome images have pixels of a first and second color. A method of evaluating an imager includes generating an image with a hand-held imaging device, the image having pixels of a first color and a second color. The image is analyzed to determine information about particles of the first and second color contained in the image. Each particle comprises contiguous pixels of the same color. The particle information is information on particle size and count of particles of the first and second colors. The image is determined to be acceptable or unacceptable based on predetermined objective criteria and the particle information. |
FILED | Friday, September 14, 2012 |
APPL NO | 13/620125 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image analysis 382/112 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 10, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20131210.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page