FedInvent™ Patents
Patent Details for Tuesday, December 31, 2013
This page was updated on Monday, March 27, 2023 at 03:54 AM GMT
Department of Health and Human Services (HHS)
| US 08616532 | Yeates |
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| FUNDED BY |
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| APPLICANT(S) | Donovan B. Yeates (Escondido, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donovan B. Yeates (Escondido, California) |
| ABSTRACT | A flow conditioner for generating and diluting an aerosol with a first inlet adapted to receive a first volume flow of pressurized gas. A second inlet is adapted to receive a second dilution gas volume flow and a third inlet adapted to receive a fluid to be converted into an aerosol. A nozzle is connected to the first and third inlet and has a nozzle orifice for outputting a first aerosol. A first dilution gas flow partitioner has a first set of openings penetrating the first dilution gas flow partitioner and a second dilution gas flow partitioner that is spaced apart from the first dilution gas partitioner and has a second set of openings penetrating the second dilution gas flow partitioner. The nozzle orifice is positioned in the proximity of the second dilution gas flow partitioner. |
| FILED | Friday, September 24, 2010 |
| APPL NO | 12/890376 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas and liquid contact apparatus 261/78.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616702 | Abrámoff |
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| FUNDED BY |
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| APPLICANT(S) | Michael Abrámoff (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Michael Abrámoff (Iowa City, Iowa) |
| ABSTRACT | Provided is a hybrid laser ophthalmoscope comprising a laser light source, a LED light source, and a holographic diffuser, wherein the holographic diffuser is configured to shape a beam of light into a Maxwellian ring. |
| FILED | Thursday, February 25, 2010 |
| APPL NO | 13/203168 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617147 | Knox et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wayne H. Knox (Pittsford, New York); Krystel R. Huxlin (Rush, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Wayne H. Knox (Pittsford, New York); Krystel R. Huxlin (Rush, New York) |
| ABSTRACT | A method for providing vision correction to a patient. The method includes: (a) measuring the degree of vision correction needed by the patient and determining the location and shape of refractive structures that need to be positioned within the cornea to partially correct a patient's vision; (b) directing and focusing femtosecond laser pulses in the blue spectral region within the cornea at an intensity high enough to change the refractive index of the cornea within a focal region, but not high enough to damage the cornea or to affect cornea tissue outside of the focal region; and (c) scanning the laser pulses across a volume of the cornea or the lens to provide the focal region with refractive structures in the cornea or the lens. Again, the refractive structures are characterized by a change in refractive index, and exhibit little or no scattering loss. |
| FILED | Friday, October 01, 2010 |
| APPL NO | 12/895978 |
| ART UNIT | 3769 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Surgery 66/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617516 | Wickline et al. |
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| FUNDED BY |
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| APPLICANT(S) | Samuel A. Wickline (St. Louis, Missouri); Hua Pan (St. Louis, Missouri); Neelesh R. Soman (St. Louis, Missouri); Gregory M. Lanza (St. Louis, Missouri); Paul H. Schlesinger (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Samuel A. Wickline (St. Louis, Missouri); Hua Pan (St. Louis, Missouri); Neelesh R. Soman (St. Louis, Missouri); Gregory M. Lanza (St. Louis, Missouri); Paul H. Schlesinger (St. Louis, Missouri) |
| ABSTRACT | The present invention provides a substantially non-lytic, non-cytotoxic anchor peptide that is capable of stably inserting into lipid membranes. In particular, the invention provides nanoparticles comprising stably inserted anchor peptides, which may be conjugated to a variety of different cargo complexes. |
| FILED | Friday, October 22, 2010 |
| APPL NO | 12/910385 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.690 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617521 | Hallahan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dennis E. Hallahan (St. Louis, Missouri); Raymond Mernaugh (St. Louis, Missouri) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Dennis E. Hallahan (St. Louis, Missouri); Raymond Mernaugh (St. Louis, Missouri) |
| ABSTRACT | A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor. |
| FILED | Monday, August 01, 2011 |
| APPL NO | 13/195570 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.341 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617531 | Cox et al. |
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| FUNDED BY |
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| APPLICANT(S) | George N. Cox (Louisville, Colorado); Mary S. Rosendahl (Broomfield, Colorado) |
| ASSIGNEE(S) | Bolder Biotechnology, Inc. (Boulder, Colorado) |
| INVENTOR(S) | George N. Cox (Louisville, Colorado); Mary S. Rosendahl (Broomfield, Colorado) |
| ABSTRACT | Disclosed is a method for refolding a protein or peptide that does not contain essential disulfides and that contains at least one free cysteine residue. Also disclosed are polymer IFN-γ conjugates that have been created by the chemical coupling of polymers such as polyethylene glycol moieties to IFN-γ, particularly via a free cysteine in the protein. Also disclosed are analogs of bioactive peptides that may be used to create longer acting versions of the peptides, including analogs of glucagon, glucagon-like peptide-1 (GLP-1), GLP-2, Gastric inhibitory peptide (GIP), PYY, exendin, ghrelin, gastrin, amylin, and oxyntomodulin. |
| FILED | Friday, December 14, 2007 |
| APPL NO | 12/519203 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/85.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617534 | Sussman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mark A. Sussman (San Diego, California); John A. Muraski (San Clemente, California) |
| ASSIGNEE(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
| INVENTOR(S) | Mark A. Sussman (San Diego, California); John A. Muraski (San Clemente, California) |
| ABSTRACT | The invention provides compositions (e.g., pharmaceutical compositions) comprising nucleic acids encoding the serine/threonine kinase PIM-1, and methods for making and using them; including methods for inducing cellular proliferation, and protecting cardiac cells from hypoxia and cellular apoptosis. The invention provides compositions (e.g., pharmaceutical compositions) comprising nucleic acids encoding PIM-1, and methods for enhancing the regenerative potential of stem cells in the heart. |
| FILED | Friday, November 14, 2008 |
| APPL NO | 12/742871 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617536 | Murray et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joseph A. Murray (Rochester, Minnesota); Eric V. Marietta (Rochester, Minnesota); Susan H. Barton (Reston, Virginia); Veena Taneja (Rochester, Minnesota); Ashutosh Mangalam (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Joseph A. Murray (Rochester, Minnesota); Eric V. Marietta (Rochester, Minnesota); Susan H. Barton (Reston, Virginia); Veena Taneja (Rochester, Minnesota); Ashutosh Mangalam (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials related to Prevotella histicola preparations. For example, Prevotella histicola preparations in the form of an oral medicament or dietary supplement (e.g., a pill, tablet, capsule) are provided. In addition, methods and materials for using a Prevotella histicola preparation provided herein as an anti-inflammatory agent are provided. |
| FILED | Wednesday, October 27, 2010 |
| APPL NO | 13/505169 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617547 | Chinnaiyan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arul Chinnaiyan (Plymouth, Michigan); David Beer (Chelsea, Michigan); Guoan Chen (Ann Arbor, Michigan); Xiaoju Wang (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Arul Chinnaiyan (Plymouth, Michigan); David Beer (Chelsea, Michigan); Guoan Chen (Ann Arbor, Michigan); Xiaoju Wang (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer. |
| FILED | Thursday, September 10, 2009 |
| APPL NO | 12/556831 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617548 | Casey |
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| FUNDED BY |
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| APPLICANT(S) | Leslie S. Casey (New York, New York) |
| ASSIGNEE(S) | Elusys Therapeutics, Inc. (Pine Brook, New Jersey) |
| INVENTOR(S) | Leslie S. Casey (New York, New York) |
| ABSTRACT | The present invention provides an antibody which binds to B. anthracis with toxin, formulations for administration of such antibodies intramuscularly, and methods of administering such antibodies prophylactically or therapeutically. |
| FILED | Wednesday, March 30, 2011 |
| APPL NO | 13/076082 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617557 | Penichet et al. |
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| FUNDED BY |
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| APPLICANT(S) | Manuel L. Penichet (Los Angeles, California); Rosendo Luria-Perez (Culver City, California); Gustavo Helguera (Buenos Aires, Arkansas) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Manuel L. Penichet (Los Angeles, California); Rosendo Luria-Perez (Culver City, California); Gustavo Helguera (Buenos Aires, Arkansas) |
| ABSTRACT | Disclosed herein are polypeptides which comprise all or part of an antibody linked to all or part of a cytokine. The cytokine sequences of the polypeptides have a modified heparin binding region which disrupts, inhibits, or reduces the ability of the cytokine to bind a heparin compound as compared to a corresponding cytokine having an unmodified heparin binding region. Also disclosed are methods of treating cancer, inducing cell proliferation, and reducing the non-specific binding and/or non-specific localization of the polypeptides. |
| FILED | Friday, March 11, 2011 |
| APPL NO | 13/581369 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/178.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617563 | Bednar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Maria M. Bednar (Durham, North Carolina); Ine Jorgensen (Durham, North Carolina); Dewey G. McCafferty (Chapel Hill, North Carolina); Raphael H. Valdivia (Carrboro, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Maria M. Bednar (Durham, North Carolina); Ine Jorgensen (Durham, North Carolina); Dewey G. McCafferty (Chapel Hill, North Carolina); Raphael H. Valdivia (Carrboro, North Carolina) |
| ABSTRACT | An antichlamydial agent comprising an inhibitor of Chlamydial Protease-like Activity Factor (CPAF). The inhibitor of CPAF can comprise a CPAF inhibitory segment and can optionally include one or more additional residues or domains. Also provided are compositions comprising an inhibitor of CPAF, methods of identifying an inhibitor of CPAF, and methods of treating a Chlamydia infection in a subject comprising administering an inhibitor of CPAF or a composition comprising an inhibitor of CPAF to the subject. |
| FILED | Monday, January 30, 2012 |
| APPL NO | 13/361706 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617573 | Chapman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Edwin Raymond Chapman (Madison, Wisconsin); Min Dong (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Edwin Raymond Chapman (Madison, Wisconsin); Min Dong (Madison, Wisconsin) |
| ABSTRACT | It is disclosed here that synaptotagmin I (syt I) and synaptotagmin II (syt II) are the cellular receptors for botulinum neurotoxin B (BoNT/B) that mediate the cellular entry and toxicity of BoNT/B. The BoNT/B binding domains of syt I and II are also disclosed. While syt I needs gangliosides for BoNT/B binding, syt II can bind to BoNT/B in the absence of gangliosides. Various nucleic acids and polypeptides that relate to the BoNT/B binding domain of syt I or II are disclosed. Further disclosed are methods of reducing BoNT/B toxicity, methods of identifying agents that can block the binding between BoNT/B and syt I or II, methods of identifying agents that can bind to the BoNT/B binding domain of syt I or II, methods of detecting BoNT/B or Clostridium botulinum and kits for use thereof. |
| FILED | Wednesday, October 26, 2011 |
| APPL NO | 13/281501 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/247.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617592 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shaoyi Jiang (Redmond, Washington); Zhiqiang Cao (Somerville, Massachusetts); Hong Xue (Pleasanton, California); Lei Zhang (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Zhiqiang Cao (Somerville, Massachusetts); Hong Xue (Pleasanton, California); Lei Zhang (Seattle, Washington) |
| ABSTRACT | Zwitterionic block copolymers and zwitterionic conjugates that advantageously self-assemble into particles, particles assembled from the zwitterionic block copolymers and zwitterionic conjugates, pharmaceutical compositions that include the self-assembled particles, and methods for delivering therapeutic and diagnostic agents using the particles. |
| FILED | Thursday, May 03, 2012 |
| APPL NO | 13/463662 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617704 | Piascik et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jeffrey Robert Piascik (Raleigh, North Carolina); Jeffrey Yates Thompson (Davie, Florida); Sonia Grego (Chapel Hill, North Carolina); Brian R. Stoner (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina); Nova Southeastern University (Ft. Lauderdale, Florida) |
| INVENTOR(S) | Jeffrey Robert Piascik (Raleigh, North Carolina); Jeffrey Yates Thompson (Davie, Florida); Sonia Grego (Chapel Hill, North Carolina); Brian R. Stoner (Chapel Hill, North Carolina) |
| ABSTRACT | A coated medical implant, such as a coated dental component, is provided, the coated medical implant including a substrate surface formed of a material comprising available hydroxyl groups and a silicon oxide coating layer chemisorbed on the substrate surface. A method for the preparation of such coated implants is also provided, the method involving application of the silicon oxide coating layer to the substrate surface by chemical vapor deposition. A dental structure is also provided, which includes a first dental component having a substrate surface formed of a material comprising available hydroxyl groups; a silicon oxide coating layer chemisorbed on the substrate surface; a silane coupling agent overlying and covalently attached to the silicon oxide layer; a dental cement overlying and coupled to the silane coupling agent; and a second dental component having a surface bonded to the dental cement. |
| FILED | Friday, October 14, 2011 |
| APPL NO | 13/273528 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/336 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617813 | Ko et al. |
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| FUNDED BY |
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| APPLICANT(S) | Minoru S. H. Ko (Cockeysville, Maryland); Geppino Falco (Rotondi, Italy); Sung-Lim Lee (Gyeongsan, South Korea); Manuela Monti (Baltimore, Maryland); Ilaria Stanghellini (Baltimore, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Minoru S. H. Ko (Cockeysville, Maryland); Geppino Falco (Rotondi, Italy); Sung-Lim Lee (Gyeongsan, South Korea); Manuela Monti (Baltimore, Maryland); Ilaria Stanghellini (Baltimore, Maryland) |
| ABSTRACT | Described herein is Zscan4, a gene exhibiting 2-cell embryonic stage and embryonic stem cell specific expression. Identification of nine Zscan4 co-expressed genes is also described. Inhibition of Zscan4 expression inhibits the 2-cell to 4-cell embryonic transition and prevents blastocyst implantation, expansion and outgrowth. Provided herein are methods of inhibiting differentiation of a stem cell, promoting blastocyst outgrowth of embryonic stem cells and identifying a subpopulation of stem cells expressing Zscan4. Further described is the identification of Trim43 as a gene exhibiting morula-specific expression. Also provided are isolated expression vectors comprising a Zscan4 promoter, or a Trim43 promoter operably linked to a heterologous polypeptide and uses thereof. Further provided are transgenic animals comprising transgenes encoding marker proteins operably linked to Zscan4 and Trim43 promoters. |
| FILED | Wednesday, December 21, 2011 |
| APPL NO | 13/332800 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617815 | Khetani et al. |
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| FUNDED BY |
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| APPLICANT(S) | Salman R. Khetani (Cambridge, Massachusetts); Sangeeta N. Bhatia (Lexington, Massachusetts) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Salman R. Khetani (Cambridge, Massachusetts); Sangeeta N. Bhatia (Lexington, Massachusetts) |
| ABSTRACT | This invention relates to methods to stabilize and/or improve the function of parenchymal cells. Also provided are systems of co-cultures of hepatocyte-stabilizing non-parenchymal cells used in bioreactor microenvironments to identify hepatic stabilizing factors by gene-expression profiling. |
| FILED | Thursday, August 04, 2005 |
| APPL NO | 11/658980 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617818 | Tsichlis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Philip N. Tsichlis (Winchester, Massachusetts); Christos Polytarchou (Boston, Massachusetts); Dimitrios Iliopoulos (Brighton, Massachusetts) |
| ASSIGNEE(S) | Tufts Medical Center (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Philip N. Tsichlis (Winchester, Massachusetts); Christos Polytarchou (Boston, Massachusetts); Dimitrios Iliopoulos (Brighton, Massachusetts) |
| ABSTRACT | MicroRNA (miRNA) profiling of cells showed unique miRNA signatures for each of three Akt isoforms. Among differentially regulated miRNA species, the miR-200 family was downregulated in Akt2-expressing cells. Akt1 knockdown inhibited expression of miR-200 and promoted TGFβ-induced epithelial-mesenchymal-transition (EMT) and a stem cell like phenotype. Carcinomas developing in MMTV-cErb2/Akt1−/− mice exhibited increased invasiveness because of EMT induced by miR-200 downregulation. EMT was found to be controlled by miRNA species that are regulated by the balance between Akt1 and Akt2, rather than overall Akt levels. |
| FILED | Friday, September 30, 2011 |
| APPL NO | 13/249477 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.140 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617823 | Rubin-Bejerano et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ifat Rubin-Bejerano (Belmont, Massachusetts); Gerald R. Fink (Chesnut Hill, Massachusetts) |
| ASSIGNEE(S) | Immunexcite, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Ifat Rubin-Bejerano (Belmont, Massachusetts); Gerald R. Fink (Chesnut Hill, Massachusetts) |
| ABSTRACT | The invention is directed to β1-6 glucans, compositions, diagnostic kits, and devices comprising the same, and methods of use thereof in modulating immune response and treating, delaying progression of, reducing the incidence or severity of cancer, infection, inflammation, and autoimmune diseases. The β1-6 glucans of certain embodiments of the invention are enriched for O-acetylated groups and/or conjugated to a solid support or linked to a targeting moiety. The β1-6 glucans of certain embodiments of the invention recruit immunoglobulin G antibodies to mediate complement and neutrophil killing. The conjugated β1-6 glucans of certain embodiments of the invention are targeted to cells to stimulate the immune response at the target location by activating complement-mediated lysis and recruitment of neutrophils. |
| FILED | Wednesday, April 29, 2009 |
| APPL NO | 12/990066 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617831 | Bottaro et al. |
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| FUNDED BY |
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| APPLICANT(S) | Donald P. Bottaro (Kensington, Maryland); Gagani P. Athauda (Miramar, Florida); Teresa Lynn Burgess (Ventura, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Amgen, Inc. (Thousand Oaks, California) |
| INVENTOR(S) | Donald P. Bottaro (Kensington, Maryland); Gagani P. Athauda (Miramar, Florida); Teresa Lynn Burgess (Ventura, California) |
| ABSTRACT | Methods for measuring c-Met levels in urine and blood samples are provided. Methods for diagnosis and prognosis evaluation for cancer are also provided. |
| FILED | Wednesday, September 26, 2012 |
| APPL NO | 13/627595 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617832 | Sundstrom |
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| FUNDED BY |
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| APPLICANT(S) | Paula Sundstrom (Lebanon, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Paula Sundstrom (Lebanon, New Hampshire) |
| ABSTRACT | The present invention features a method for identifying an agent that inhibits Candida albicans-mediated differentiation of keratinocytes. Agents identified by the screening assay of the invention find application in the prevention and treatment of candidiasis. |
| FILED | Friday, August 13, 2010 |
| APPL NO | 13/391722 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617833 | Wang |
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| FUNDED BY |
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| APPLICANT(S) | Zhao Yi Wang (Bellevue, Nebraska) |
| ASSIGNEE(S) | Creighton University (Omaha, Nebraska) |
| INVENTOR(S) | Zhao Yi Wang (Bellevue, Nebraska) |
| ABSTRACT | The present invention provides isolated polypeptides having an amino acid sequence having at least 70% identity to SEQ ID NO:20, wherein the polypeptide has ER-α36 activity. The invention further provides methods for identifying agents that bind to such polypeptides, methods for detecting such polypeptides, and methods for altering the activity of such polypeptides. Also provided are antibodies that specifically bind to an amino acid sequence depicted at SEQ ID NO:1, or an immunogenic fragment thereof, and methods for making and using such antibodies. |
| FILED | Tuesday, August 07, 2012 |
| APPL NO | 13/568145 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617838 | Latz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eicke Latz (Worcester, Massachusetts); Brian G. Monks (Sudbury, Massachusetts); Douglas T. Golenbock (Wellesley, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Eicke Latz (Worcester, Massachusetts); Brian G. Monks (Sudbury, Massachusetts); Douglas T. Golenbock (Wellesley, Massachusetts) |
| ABSTRACT | The invention includes fusion polypeptides including a first fluorescent protein, e.g., a FRET donor protein, a second fluorescent protein, e.g., a FRET acceptor protein, and, linked to at least one of the fluorescent (e.g., FRET donor or FRET acceptor) proteins, an Fc-region of an immunoglobulin. The polypeptide can be immobilized with respect to a surface via the Fc-region even in the absence of antibodies to either the FRET donor protein or FRET acceptor protein, and can be used as a calibration standard for fluorescence resonance energy transfer includes a polypeptide. |
| FILED | Tuesday, September 20, 2005 |
| APPL NO | 11/575363 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617877 | Marban et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eduardo Marban (Beverly Hills, California); Jennifer E. Van Eyk (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Eduardo Marban (Beverly Hills, California); Jennifer E. Van Eyk (Baltimore, Maryland) |
| ABSTRACT | The invention relates to secreted proteins from cardiac stem cells (cardiospheres and cardiosphere-derived cells) or myocytes for diagnostic and/or therapeutic use. |
| FILED | Monday, November 03, 2008 |
| APPL NO | 12/740887 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617888 | Jin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shouguang Jin (Gainesville, Florida); Candace Bichsel (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Shouguang Jin (Gainesville, Florida); Candace Bichsel (Gainesville, Florida) |
| ABSTRACT | A modified P. aeruginosa type III secretion system has been developed that efficiently delivers selected proteins into a host cell. In one example, a functional nuclear Cre Recombinase is injected into embryonic stem (ES) cells and can be used to induce pluripotent stem (iPS) cells. This method of in vitro lineage directed differentiation prevents insertional mutagenesis and provides a route to selected stem cell renewal and cell-based therapies. |
| FILED | Friday, July 23, 2010 |
| APPL NO | 12/842448 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617889 | Anversa |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Piero Anversa (Boston, Massachusetts) |
| ASSIGNEE(S) | New York Medical College (Valhalla, New York) |
| INVENTOR(S) | Piero Anversa (Boston, Massachusetts) |
| ABSTRACT | Methods, compositions, and kits for repairing damaged myocardium and/or myocardial cells including the administration of cytokines, variants of cytokines, cardiac stem cells, or combinations thereof are disclosed and claimed. In addition, methods, compositions, and kits for forming coronary vasculature including the administration of cytokines, variants of cytokines, cardiac stem cells, or combinations thereof are described. In particular, administration of variants of hepatocyte growth factor, such as NK1, 1K1, and HP11, are useful for the repair and/or regeneration of damaged myocardium or formation of coronary vasculature. Methods of activating cardiac stem cells in vitro are also disclosed. |
| FILED | Tuesday, July 17, 2012 |
| APPL NO | 13/551436 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617892 | Borden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark A. Borden (Boulder, Colorado); Eric G. Lima (Patterson, New York); Clark T. Hung (Ardsley, New York); Shashank Ramesh Sirsi (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Mark A. Borden (Boulder, Colorado); Eric G. Lima (Patterson, New York); Clark T. Hung (Ardsley, New York); Shashank Ramesh Sirsi (New York, New York) |
| ABSTRACT | A hydrogel tissue engineering scaffold having microbubbles dispersed therein is disclosed. Also, a system for cell culturing including a controller and actuator to apply dynamic deformational loading to a hydrogel is disclosed. Also disclosed are methods for producing hydrogels with microbubbles and for culturing cells using hydrogels with microbubbles. |
| FILED | Tuesday, August 31, 2010 |
| APPL NO | 13/393273 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/397 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617899 | De Bruyker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dirk De Bruyker (Palo Alto, California); Ali Asgar Saleem Bhagat (Cincinnati, Ohio); Alan G. Bell (Mountain View, California); Michael I. Recht (Mountain View, California); Francisco E. Torres (San Jose, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Dirk De Bruyker (Palo Alto, California); Ali Asgar Saleem Bhagat (Cincinnati, Ohio); Alan G. Bell (Mountain View, California); Michael I. Recht (Mountain View, California); Francisco E. Torres (San Jose, California) |
| ABSTRACT | A method and device for merging and mixing at least two separate and distinct fluid drops on a substrate, includes a drop merging area on the surface, where a first magnetic material is placed at a first location. A first drop of fluid is then placed at the first location on the surface, resulting in the first magnetic material being at least partially positioned within the first drop of fluid. A second drop of fluid is then placed at a second location on the surface of the drop merging area. A magnetic field is applied by a varying magnetic field generator to at least a portion of the drop merge area of the substrate, which includes at least the first location on the substrate. The varying magnetic field will act on the first magnetic material to move the first magnetic material within the first drop of fluid, causing a stirring of the fluid. A drop merging force from a drop merging mechanism is applied to at least one of the first drop of fluid and the second drop of fluid within the drop merge area. This causes at least one of the first drop of fluid and the second drop of fluid to move toward the other and make contact. The internal stirring of the fluid in the first drop of fluid by the movement of the magnetic material enhances the mixing of the constituents of the first drop of fluid and the constituents of the second drop of fluid. |
| FILED | Thursday, February 14, 2008 |
| APPL NO | 12/031519 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/147 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618049 | Kent et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stephen B. H. Kent (San francisco, California); Youhei Soma (Tokyo, Japan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen B. H. Kent (San francisco, California); Youhei Soma (Tokyo, Japan) |
| ABSTRACT | Compositions and methods related to ester insulin or derivatives thereof are provided. The compositions include GluA4-ThrB30 ester insulin, in which side chains of GluA4 and ThrB30 of native human insulin or an insulin analogue such as insulin lispro are covalently linked via a single ester bond. The ester insulin is efficiently folded, forming the desired disulfides. The ThrB30-GluA4 ester bond can be cleaved in vitro or in vivo to give the desired folded insulin with full biological activity. The ester insulin is readily prepared by total chemical synthesis, and amendable to cost-effective, large scale manufacturing. Also provided are pharmaceutical compositions and kits for use in practicing the subject methods. Also provided are methods of using the subject compositions and kits in the treatment of a variety of different disease conditions, particularly glucose metabolic disorders such as diabetes and obesity. |
| FILED | Tuesday, September 07, 2010 |
| APPL NO | 13/394646 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/6.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618061 | Szeto |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hazel Szeto (New York, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Hazel Szeto (New York, New York) |
| ABSTRACT | The invention provides a method for reducing oxidative damage in a mammal, a removed organ, or a cell in need thereof. The method comprises administering an effective amount of an aromatic cationic peptide. The aromatic cationic peptide has (a) at least one net positive charge; (b) a minimum of three amino acids; (c) a maximum of about twenty amino acids, (d) a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3 pm is the largest number that is less than or equal to r+1; (e) a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 3a or 2a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1; and (f) at least one tyrosine or tryptophan amino acid. |
| FILED | Monday, July 26, 2010 |
| APPL NO | 12/843333 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618063 | Brady et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Scott Thomas Brady (Chicago, Illinois); Gerardo Andres Morfini (Chicago, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Scott Thomas Brady (Chicago, Illinois); Gerardo Andres Morfini (Chicago, Illinois) |
| ABSTRACT | The present invention relates to methods for restoring fast axonal transport in a cell which expresses a pathological synuclein protein and for treating a synucleinopathy using a Protein Kinase C mu or Src-Family Tyrosine Kinase inhibitor. |
| FILED | Wednesday, April 09, 2008 |
| APPL NO | 12/099947 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/20.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618068 | Perrine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susan P Perrine (Weston, Massachusetts); Douglas V Faller (Weston, Massachusetts); Ronald J Berenson (Mercer Island, Washington) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); Hemaquest Pharmaceuticals, Inc. (Seattle, Washington) |
| INVENTOR(S) | Susan P Perrine (Weston, Massachusetts); Douglas V Faller (Weston, Massachusetts); Ronald J Berenson (Mercer Island, Washington) |
| ABSTRACT | Disclosed herein are methods and low dose regimens for increasing fetal hemoglobin levels in patients with red blood cell disorders, such as beta thalassemia, sickle cell disease, other anemias, or blood loss. Fetal and total hemoglobin levels and red blood cell counts are increased by administering 2,2-dimethylbutyrate (DMB) alone or in combination with hydroxyurea, decitabine or an HDAC inhibitor. Treatment can be continued for at least two weeks. |
| FILED | Wednesday, December 08, 2010 |
| APPL NO | 12/963490 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/43 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618073 | Deshmukh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mohanish Deshmukh (Chapel Hill, North Carolina); Adam Kole (Chapel Hill, North Carolina); Vijay Swahari (Cary, North Carolina); Scott Hammond (Pittsboro, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Mohanish Deshmukh (Chapel Hill, North Carolina); Adam Kole (Chapel Hill, North Carolina); Vijay Swahari (Cary, North Carolina); Scott Hammond (Pittsboro, North Carolina) |
| ABSTRACT | The present invention relates to the regulation of apoptosis and expression of the BH3-only family of genes by miR-29. The invention further relates to the use of miR-29 to protect cells from apoptosis and to treat disorders associated with apoptosis. |
| FILED | Friday, July 22, 2011 |
| APPL NO | 13/811003 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618082 | Mukhtar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hasan Mukhtar (Fitchburg, Wisconsin); Mohammad Saleem Bhat (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hasan Mukhtar (Fitchburg, Wisconsin); Mohammad Saleem Bhat (Madison, Wisconsin) |
| ABSTRACT | The present invention provides methods for the prevention, treatment and/or alleviation of skin disorders and skin cancers and prevention, treatment and/or alleviation of prostate cancer and pancreatic cancer by administering a Lupeol-derived anti-tumor compound. The invention further provides pharmaceutical and nutraceutical compositions containing Lupeol-derived anti-tumor compounds. |
| FILED | Wednesday, March 02, 2005 |
| APPL NO | 10/906691 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/169 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618088 | Wen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rong Wen (Bala Cynwyd, Pennsylvania); Zhijun Luo (Chestnut Hill, Massachusetts); Alan M. Laties (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Rong Wen (Bala Cynwyd, Pennsylvania); Zhijun Luo (Chestnut Hill, Massachusetts); Alan M. Laties (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for inhibiting unwanted angiogenesis, particularly those of ocular tissues. The treatment, inhibition, and/or prevention of choroidal neovasculature (CNV) is provided, along with an animal model for CNV and imaging techniques that permit the screening of potential agents as anti-angiogenesis and anti-CNV agents. |
| FILED | Thursday, March 29, 2012 |
| APPL NO | 13/433739 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/185 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618090 | Desai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanjay A. Desai (Potomac, Maryland); Ajay D. Pillai (Andhra Pradesh, India) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Sanjay A. Desai (Potomac, Maryland); Ajay D. Pillai (Andhra Pradesh, India) |
| ABSTRACT | Disclosed are inhibitors of the plasmodial surface anion channel (PSAC) inhibitors and the use thereof in treating or preventing malaria in an animal such as a human, comprising administering an effective amount of an inhibitor or a combination of inhibitors. An example of such an inhibitor is a compound of formula I, Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 to R7 are as described herein. |
| FILED | Wednesday, July 15, 2009 |
| APPL NO | 13/055104 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/211.40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618162 | Carlier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul Carlier (Blacksburg, Virginia); Jeffrey Bloomquist (Blacksburg, Virginia); Sally Paulson (Blacksburg, Virginia); Eric Wong (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Paul Carlier (Blacksburg, Virginia); Jeffrey Bloomquist (Blacksburg, Virginia); Sally Paulson (Blacksburg, Virginia); Eric Wong (Blacksburg, Virginia) |
| ABSTRACT | The present invention includes insecticidal carbamates that are useful, for example, for the control of insects, such as mosquitoes, which can be used in applications where exposure to and/or contact with humans is likely. The insecticides of the present invention include phenyl N-methyl carbamates and compositions comprising them that exhibit species-selective inhibition of acetylcholinesterase (AChE) and are preferably toxic to mosquitoes but not humans. Of particular interest are compounds of Formula (I) and Formula (II): Compounds of Formula (I) and Formula (II) are especially suitable for insecticide treated nets and indoor residual spraying for mosquito control. |
| FILED | Thursday, January 26, 2012 |
| APPL NO | 13/358586 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618248 | Gygi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven P. Gygi (Foxborough, Massachusetts); Judit Villen (Boston, Massachusetts); Sean Beausoleil (Merrimack, New Hampshire) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Steven P. Gygi (Foxborough, Massachusetts); Judit Villen (Boston, Massachusetts); Sean Beausoleil (Merrimack, New Hampshire) |
| ABSTRACT | The present invention relates to phosphopeptide compositions and anti-phosphopeptide antibody compositions. Also provided are methods of identifying phosphorylation sites in phosphorylated peptides and phosphorylation site motifs. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 11/980279 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618251 | Ravetch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey V. Ravetch (New York, New York); Rene G. Ott (Vienna, Austria) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Jeffrey V. Ravetch (New York, New York); Rene G. Ott (Vienna, Austria) |
| ABSTRACT | The present invention provides reagents, methods and systems for predicting the inhibitory activity of an antibody or variant thereof comprising: determining a binding affinity of the antibody or variant thereof to a Fc activating receptor; determining a binding affinity of the antibody or variant thereof to a Fc inhibitory receptor, and calculating the ratio of said activating binding affinity to said inhibitory binding affinity (A/I ratio), wherein the magnitude of said ratio is less than one (1). |
| FILED | Tuesday, November 09, 2010 |
| APPL NO | 12/942824 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618256 | Cox |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George N. Cox (Louisville, Colorado) |
| ASSIGNEE(S) | Bolder Biotechnology (Boulder, Colorado) |
| INVENTOR(S) | George N. Cox (Louisville, Colorado) |
| ABSTRACT | The growth hormone supergene family comprises greater than 20 structurally related cytokines and growth factors. A general method is provided for creating site-specific, biologically active conjugates of these proteins. The method involves adding cysteine residues to non-essential regions of the proteins or substituting cysteine residues for non-essential amino acids in the proteins using site-directed mutagenesis and then covalently coupling a cysteine-reactive polymer or other type of cysteine-reactive moiety to the proteins via the added cysteine residue. Disclosed herein are preferred sites for adding cysteine residues or introducing cysteine substitutions into the proteins, and the proteins and protein derivatives produced thereby. |
| FILED | Friday, May 13, 2011 |
| APPL NO | 13/107021 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/351 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618267 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | L. David Williams (Fremont, California); Michael S. Hershfield (Durham, North Carolina); Susan J. Kelly (Chapel Hill, North Carolina); Mark G. P. Saifer (San Carlos, California); Merry R. Sherman (San Carlos, California) |
| ASSIGNEE(S) | Mountain View Pharmaceuticals, Inc. (Menlo Park, California); Duke University (Durham, North Carolina) |
| INVENTOR(S) | L. David Williams (Fremont, California); Michael S. Hershfield (Durham, North Carolina); Susan J. Kelly (Chapel Hill, North Carolina); Mark G. P. Saifer (San Carlos, California); Merry R. Sherman (San Carlos, California) |
| ABSTRACT | A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/083152 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/412 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618269 | Thorson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jon Thorson (Middleton, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Jon Thorson (Middleton, Wisconsin) |
| ABSTRACT | The present invention provides glycorandomized structures and combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. The glycosyltransferase may be one that is associated with or involved in production of natural secondary metabolites, or one which is putatively associated with or involved in production of natural secondary metabolites. The glycosyltransferase may show significant flexibility with respect to its NDP-sugar donors and/or its aglycons. NDP-sugar donors may be commercially available, or may be produced by utilizing mutant or wild type nucleotidyltransferases significant flexibility with respect to their substrates. |
| FILED | Tuesday, April 17, 2012 |
| APPL NO | 13/448811 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Organic compounds 536/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618281 | Lindsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jonathan S. Lindsey (Raleigh, North Carolina); Lianhe Yu (Highpoint, North Carolina); Patchanita Thamyongkit (Bangkok, Thailand); Anil D. Bhise (Pune, India) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Jonathan S. Lindsey (Raleigh, North Carolina); Lianhe Yu (Highpoint, North Carolina); Patchanita Thamyongkit (Bangkok, Thailand); Anil D. Bhise (Pune, India) |
| ABSTRACT | A method of making a compound of Formula I′ comprises reacting a compound of the formula DLCHO, with a compound of the formula to produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices. |
| FILED | Friday, August 31, 2012 |
| APPL NO | 13/600808 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/145 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618352 | Welsh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael J. Welsh (Riverside, Iowa); Christopher S. Rogers (North Liberty, Iowa); Randall Prather (Rocheport, Missouri); John Engelhardt (Iowa City, Iowa); Ziying Yan (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Michael J. Welsh (Riverside, Iowa); Christopher S. Rogers (North Liberty, Iowa); Randall Prather (Rocheport, Missouri); John Engelhardt (Iowa City, Iowa); Ziying Yan (Iowa City, Iowa) |
| ABSTRACT | The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of making and using such animal models in the identification and characterization of therapies for the diseases and conditions. |
| FILED | Wednesday, September 17, 2008 |
| APPL NO | 12/283980 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618475 | Clemmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David E. Clemmer (Bloomington, Indiana); Stormy L. Koeniger (Evanston, Illinois); Stephen J. Valentine (Bloomington, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | David E. Clemmer (Bloomington, Indiana); Stormy L. Koeniger (Evanston, Illinois); Stephen J. Valentine (Bloomington, Indiana) |
| ABSTRACT | An ion mobility spectrometer comprises a drift tube defining a drift tube inlet configured to receive ions and a drift tube outlet. The drift tube is configured to separate ions in time as a function of ion mobility. The drift tube defines a first ion activation region between the drift tube inlet and the drift tube outlet. The first ion activation region is configured to selectively induce structural changes in at least some of the ions. |
| FILED | Wednesday, March 02, 2011 |
| APPL NO | 13/038544 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618510 | Palmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Amy E. Palmer (Boulder, Colorado); Ralph Jimenez (Boulder, Colorado); Kevin Dean (Lafayette, Colorado); Jennifer Lubbeck (Boulder, Colorado); Lloyd M. Davis (Tullahoma, Tennessee) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado); University of Tennessee Research Foundation (Knoxville, Tennessee); National Institute of Standards and Technology (Gaithersburg, Maryland) |
| INVENTOR(S) | Amy E. Palmer (Boulder, Colorado); Ralph Jimenez (Boulder, Colorado); Kevin Dean (Lafayette, Colorado); Jennifer Lubbeck (Boulder, Colorado); Lloyd M. Davis (Tullahoma, Tennessee) |
| ABSTRACT | Devices and methods for screening emissive properties of a cell, such as the resistance to photobleaching or other photophysical property. In one example, a device may include a microfluidic reservoir having at least an input channel for receiving the cell, a main channel fluidly coupled with the input channel, at least a first output channel and a second output channel, the first and second output channels fluidly coupled with the main channel; and a multibeam interrogation section generating a plurality of light beams impinging upon the main channel of the microfluidic reservoir. As a cell passes from the input channel through the main channel of the microfluidic reservoir, the cell is exposed to the plurality of light beams thereby generating emissions that are received by a signal processing section. A cell trapping section selectively diverts the cell to the second output channel if the cell contains desired emissive properties. |
| FILED | Saturday, January 28, 2012 |
| APPL NO | 13/360706 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/461.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619237 | Hillman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Matthew B. Bouchard (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Matthew B. Bouchard (New York, New York) |
| ABSTRACT | Laser-Scanning Intersecting Plane Tomography (L-SIPT) can provide a non-contact imaging geometry that can allow high speed volumetric scanning, such as of non-scattering to moderately scattering tissues. The L-SIPT imaging apparatus can include a first lens, located and configured to receive from a sample light received from different depths of the sample. A first light redirector can be located and configured to receive via the first lens and to redirect light received from the different depths of the sample to provide redirected light to a light detector capable of detecting individual measurements of light at different locations along a first direction. A second light redirector can be located and configured to redirect light received from a light source to provide redirected light to the sample, wherein the second light redirector is in a specified spatial relationship to the first light redirector, and wherein the first and second light redirectors are configured to be adjusted during a scan of the sample so as to provide the specified spatial relationship during the scan. |
| FILED | Monday, December 06, 2010 |
| APPL NO | 12/961074 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619264 | Garty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Guy Garty (Dobbs Ferry, New York); David J. Brenner (New York, New York); Gerhard Randers-Pehrson (Ossining, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Guy Garty (Dobbs Ferry, New York); David J. Brenner (New York, New York); Gerhard Randers-Pehrson (Ossining, New York) |
| ABSTRACT | In an apparatus and system for focusing optics an objective lens is configured to collect light from a region of an object to be imaged, said region having a feature with a known geometric characteristic, wherein the geometric characteristic is known before the feature is imaged by the optical device. A focusing sensor is configured to observe a shape of the feature and a splitter is configured to split the collected light into a first portion and a second portion, and directing said first portion through a weak cylindrical lens to the focusing sensor. A processor is configured to analyze the observed shape and determine whether the observed shape of the feature has a predetermined relationship to the known geometric characteristic and a mechanism is configured to autofocus the optical device by moving at least one of the objective lens and the object to be imaged in response to the analysis and determination of the processor. In some embodiments, the feature can be a fluorescent bead. In some embodiments, the splitting step can be accomplished with a dichroic mirror. In other embodiments, the splitting step can be accomplished with a partial mirror. In some embodiments, the known geometric characteristic of the feature can be substantially spherical, the observed shape can be an oval, and the predetermined relationship can be an allowable aspect ratio of the oval. In some embodiments, the allowable aspect ratio can be approximately one. |
| FILED | Wednesday, January 12, 2011 |
| APPL NO | 13/004923 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620404 | Mistretta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles A. Mistretta (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Charles A. Mistretta (Madison, Wisconsin) |
| ABSTRACT | A system and method for generating time-resolved 3D medical images of a subject includes acquiring a time series of two-dimensional (2D) data sets from a portion of the subject using a magnetic resonance imaging (MRI) system and reconstructing the time series of 2D data sets into a 2D time series of images of the subject having a given frame rate. The process also includes acquiring a time-independent, 3D volume of the portion of the subject and combining the 2D time series of images of the subject with the time-independent 3D volume of the subject to generate a set of time-dependent 3D volume images of the portion of the subject at the given frame rate. |
| FILED | Tuesday, July 26, 2011 |
| APPL NO | 13/191388 |
| ART UNIT | 3768 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery 6/410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620410 | Frangioni |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John V. Frangioni (Wayland, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | John V. Frangioni (Wayland, Massachusetts) |
| ABSTRACT | A medical imaging system provides simultaneous rendering of visible light and fluorescent images. The system may employ dyes in a small-molecule form that remain in a subject's blood stream for several minutes, allowing real-time imaging of the subject's circulatory system superimposed upon a conventional, visible light image of the subject. The system may provide an excitation light source to excite the fluorescent substance and a visible light source for general illumination within the same optical guide used to capture images. The system may be configured for use in open surgical procedures by providing an operating area that is closed to ambient light. The systems described herein provide two or more diagnostic imaging channels for capture of multiple, concurrent diagnostic images and may be used where a visible light image may be usefully supplemented by two or more images that are independently marked for functional interest. |
| FILED | Tuesday, July 03, 2007 |
| APPL NO | 12/307204 |
| ART UNIT | 3777 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery 6/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620441 | Greenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. Greenberg (Los Angeles, California); Matthew J. McMahon (Los Angeles, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert J. Greenberg (Los Angeles, California); Matthew J. McMahon (Los Angeles, California) |
| ABSTRACT | In order to generate the smallest phosphenes possible, it is advantageous to selectively stimulate smaller cells. By hyperpolarizing the somas of the large cells selectively with sub-threshold anodic ‘pre-pulse’ stimuli (making them more difficult to stimulate) and then selectively depolarize the smaller cells one can selectively stimulate smaller cells. Alternatively, one can hyperpolarize the dendrites of the cells with larger dendritic fields by applying sub-threshold anodic currents on surrounding electrodes and then depolarizing the smaller cells in the center. Further, one can manipulate the phases of an individual biphasic wave to affect selective stimulation resulting in more focal responses. It is possible to increase resolution with the ‘pre-pulse’ described above. One can also effect resolution by modifying the pulse order of the cathodic and anodic phases. Further, one can isolate the effect of the phases by separating them in time (long inter-phase interval) or by making one of the phases long and low amplitude—always keeping equal total charge for the two phases. As an example, one can preferentially stimulate smaller ganglion cells by providing a longer sub-threshold anodic pulse balanced with a shorter supra-threshold cathodic pulse. Preferentially stimulating the smaller ganglion cells will allow stimulation of different brightness levels while maintaining high spatial resolution. |
| FILED | Tuesday, June 15, 2010 |
| APPL NO | 12/815988 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620442 | Horsager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan Matthew Horsager (Los Angeles, California); Geoffrey M. Boynton (Seattle, Washington); Ione Fine (Seattle, Washington); Robert J. Greenberg (Los Angeles, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Alan Matthew Horsager (Los Angeles, California); Geoffrey M. Boynton (Seattle, Washington); Ione Fine (Seattle, Washington); Robert J. Greenberg (Los Angeles, California) |
| ABSTRACT | The present invention is a method of stimulating visual neurons to create the perception of light. A visual prosthesis electrically stimulating the retina with implanted electrodes exhibits interaction between electrodes stimulated closely together in both space and time. The method of the present invention includes determining a minimum distance at which spatiotemporal interactions occur, determining a minimum time at which spatiotemporal interactions occur, and avoiding stimulation of electrodes within the minimum distance during the minimum time. The minimum are ideally established for each individual patient. Alternatively, approximate minimums have been established by the applicants at 2 mm and 1.8 μsec. |
| FILED | Thursday, January 27, 2011 |
| APPL NO | 13/014968 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620443 | Roy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arup Roy (Valencia, California); Robert J. Greenberg (Los Angeles, California) |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Arup Roy (Valencia, California); Robert J. Greenberg (Los Angeles, California) |
| ABSTRACT | Stimulation inputs are provided to a visual prosthesis implant. The images captured by a video decoder are received and digitized to provide a plurality of video frames; integrity of the video frames is checked, the checked video frames are filtered, and the filtered video frames are converted to stimulation inputs. A similar system is also disclosed. |
| FILED | Friday, June 29, 2012 |
| APPL NO | 13/538987 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620457 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiangsheng Zheng (Birmingham, Alabama); Michael E. Benser (Birmingham, Alabama); Raymond E. Ideker (Birmingham, Alabama); Gregory P. Walcott (Wilsonville, Alabama); Steven D. Girouard (Woodbury, Minnesota) |
| ASSIGNEE(S) | UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Xiangsheng Zheng (Birmingham, Alabama); Michael E. Benser (Birmingham, Alabama); Raymond E. Ideker (Birmingham, Alabama); Gregory P. Walcott (Wilsonville, Alabama); Steven D. Girouard (Woodbury, Minnesota) |
| ABSTRACT | An implantable system for the defibrillation of the atria of a patient's heart comprises (a) a first catheter configured for insertion into the right atrium of the heart, preferably without extending into the right ventricle of the heart; a first atrial defibrillation electrode carried by the first catheter and positioned at the atrial septum of the heart (i.e., an atrial septum electrode); (b) a second atrial defibrillation electrode which together with the first atrial defibrillation electrode provides a pair of atrial defibrillation electrodes that are configured for orientation in or about the patient's heart to effect atrial defibrillation, and (c) a pulse generator operatively associated with the pair of atrial defibrillation electrodes for delivering a first atrial defibrillation pulse to the heart of the patient. The second electrode may be configured for positioning through the coronary sinus ostium and in the coronary sinus or a vein on the surface of the left ventricle, such as the great vein. An additional electrode configured for positioning in the superior vena cava, right atrium (including the right atrial appendage, or the right ventricle may also be included, and the pulse generator may be configured or programmed for concurrently delivering a first defibrillation pulse through the additional electrode and the atrial septum electrode, and a second defibrillation pulse through the atrial septum electrode and the second electrode. Electrode assemblies and methods useful for carrying out the invention are also disclosed. |
| FILED | Tuesday, January 17, 2006 |
| APPL NO | 11/333503 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/122 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620592 | Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Javed Khan (Derwood, Maryland); Markus Ringner (Lund, Sweden); Carsten Peterson (Lund, Sweden); Paul Meltzer (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Javed Khan (Derwood, Maryland); Markus Ringner (Lund, Sweden); Carsten Peterson (Lund, Sweden); Paul Meltzer (Rockville, Maryland) |
| ABSTRACT | A method of diagnosing, predicting, or prognosticating about a disease that includes obtaining experimental data, wherein the experimental data is high dimensional data, filtering the data, reducing the dimensionality of the data through use of one or more methods, training a supervised pattern recognition method, ranking individual data points from the data, wherein the ranking is dependent on the outcome of the supervised pattern recognition method, choosing multiple data points from the data, wherein the choice is based on the relative ranking of the individual data points, and using the multiple data points to determine if an unknown set of experimental data indicates a diseased condition, a predilection for a diseased condition, or a prognosis about a diseased condition. |
| FILED | Monday, October 31, 2011 |
| APPL NO | 13/285687 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08616070 | Kudo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rance Tetsuo Kudo (Newbury Park, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rance Tetsuo Kudo (Newbury Park, California) |
| ABSTRACT | Methods of/for testing fire fighting vehicle foam delivery systems using an environmentally benign fluid. Systems and methods test the foam delivery systems' piping, valves, pump, proportioner, educator, and nozzles while minimizing the release of Aqueous Film Forming Foam to the environment. The testing system complies with the National Fire Protection Association. |
| FILED | Monday, September 12, 2011 |
| APPL NO | 13/229960 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/861 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616071 | Kudo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rance Tetsuo Kudo (Newbury Park, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rance Tetsuo Kudo (Newbury Park, California) |
| ABSTRACT | Systems of/for testing fire fighting vehicle arm delivery systems using an environmentally benign fluid. Systems test the foam delivery systems' piping, values, pump, proportioner, educator, and nozzles while minimizing the release of Aqueous Film Forming Foam to the environment. The testing system complies with the National Fire Protection Association. |
| FILED | Monday, September 12, 2011 |
| APPL NO | 13/230597 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/861 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616129 | Barrow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ryan Barrow (Swan Point, Maryland); James Mackie-Smith (Hughesville, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ryan Barrow (Swan Point, Maryland); James Mackie-Smith (Hughesville, Maryland) |
| ABSTRACT | A cartridge useful as an activator of other systems, and related method of manufacture. The cartridge's casing includes a fuse delimited by placing a plate at each end staked to the casing for fixing the fuse. This configuration permits precise control of the length of the fuse during manufacture, eliminates the need for separate structures in the casing to aid fuse location, and simplifies manufacture and assembly. This configuration supports the fuse lessening stresses that can lead to fractures. A portion of the casing is thinned by a preselected amount to permit fracturing of the casing to launch the projectile. The projectile may be attached to the cartridge casing more simply, e.g. by screw threading. |
| FILED | Friday, August 19, 2011 |
| APPL NO | 13/137477 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/464 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616328 | Daraio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institue of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Chiara Daraio (Pasadena, California); Fernando Fraternali (Avellino, Italy) |
| ABSTRACT | A tensegrity apparatus having multiple tensegrity units for the transmission of solitary waves with adjustable profiles into a material or structure, and the detection of such waves from a material or structure. |
| FILED | Thursday, February 21, 2013 |
| APPL NO | 13/772904 |
| ART UNIT | 2832 — Fluid Handling and Dispensing |
| CURRENT CPC | Acoustics 181/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616329 | Welter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Air Force (Washington D.C., Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | John T Welter (Fairborn, Ohio); Shamachary Sathish (Bellbrook, Ohio); Daniel Christensen (Omaha, Nebraska); Jason D Heebl (El Segundo, California); Philip Brodrick (Cincinnati, Ohio); Matthew R Cherry (Dayton, Ohio) |
| ABSTRACT | A broadband acoustic lens and method of designing same is provided for focusing an incident acoustic wave. The broadband lens includes a plurality of concentric rings, where each concentric ring of the plurality of concentric rings has a ring width, and a plurality of gaps, where each gap of the plurality of gaps has a spacing. The concentric rings are separated by a spacing corresponding to a gap of the plurality of gaps. The widths of the plurality of concentric rings and the spacings of the plurality of gaps are arranged such that the incident acoustic wave is focused to a spot within a sub-wavelength of the incident acoustic wave in air. The arrangement of the widths of the plurality of concentric rings and spacings of the plurality of gaps is aperiodic. |
| FILED | Tuesday, October 30, 2012 |
| APPL NO | 13/663674 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Acoustics 181/176 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616496 | Hardy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian S. Hardy (El Segundo, California); Jerome K. Fuller (Van Nuys, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Brian S. Hardy (El Segundo, California); Jerome K. Fuller (Van Nuys, California) |
| ABSTRACT | Embodiments of the invention relate to systems and methods for a self-deploying vehicle drag device. In one embodiment, a drag device for a vehicle can be provided. The drag device can include a chute body, wherein the chute body is connected to the vehicle. The drag device can also include at least one collapsible member mounted to the chute body, wherein the at least one collapsible member and chute body are maintained in respective compressed configurations until deployed. Furthermore, the drag device can include at least one device adapted to release the chute body from the vehicle, wherein the chute body and the at least one collapsible member are deployed in expanded configurations with respect to the vehicle. |
| FILED | Wednesday, August 03, 2011 |
| APPL NO | 13/197333 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/113 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616721 | Woodall, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert C. Woodall, Jr. (Panama City, Florida) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert C. Woodall, Jr. (Panama City, Florida) |
| ABSTRACT | A solar awning system is provided with a spool housing containing a sheet of flexible solar light array material rolled into a spool within the spool housing. The spool is rotatably mounted for spooling and unspooling the flexible sheet to and from the spool housing. The spool housing may be attached to a wall or other object or mounted on supports to quickly provide a shaded and lighted region at a desired location. The flexible sheet is quickly retracted into the spool housing to pack up, whereupon the spool housing protects the flexible solar light array material for subsequent use. |
| FILED | Friday, November 04, 2011 |
| APPL NO | 13/373246 |
| ART UNIT | 2885 — Optics |
| CURRENT CPC | Illumination 362/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616832 | Smoke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jason Smoke (Phoenix, Arizona); Bradley Reed Tucker (Chandler, Arizona); Bob Mitlin (Scottsdale, Arizona); Dan Crites (Mesa, Arizona); Rajiv Rana (Phoenix, Arizona); Alexander MirzaMoghadam (Phoenix, Arizona) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Jason Smoke (Phoenix, Arizona); Bradley Reed Tucker (Chandler, Arizona); Bob Mitlin (Scottsdale, Arizona); Dan Crites (Mesa, Arizona); Rajiv Rana (Phoenix, Arizona); Alexander MirzaMoghadam (Phoenix, Arizona) |
| ABSTRACT | A gas turbine engine assembly includes a housing including an annular duct wall that at least partially defines a mainstream hot gas flow path; a stator assembly with a stator vane extending into the mainstream gas flow; and a turbine rotor assembly upstream of the stator assembly and defining a turbine cavity with the stator assembly. The turbine rotor assembly includes a rotor disk having a forward side and an aft side, a rotor platform positioned on a periphery of the rotor disk, the rotor platform defining an aft flow discourager, a rotor blade mounted on the rotor platform extending into the mainstream gas flow, and an aft seal plate mounted on the aft side of the rotor disk. The aft seal plate has a radius such that the aft seal plate protects the rotor disk from hot gas ingestion. |
| FILED | Monday, November 30, 2009 |
| APPL NO | 12/627609 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616852 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wangen Lin (South Glastonbury, Connecticut); Robert W. Jackson (Simsbury, Connecticut); Andrew L. Haynes (Glastonbury, Connecticut); John E. Matz (Natick, Massachusetts); Adam Quagliaroli (Windsor Locks, Connecticut); Samuel T. Davidson (Suffield, Connecticut); Herbert A. Chin (Portland, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Wangen Lin (South Glastonbury, Connecticut); Robert W. Jackson (Simsbury, Connecticut); Andrew L. Haynes (Glastonbury, Connecticut); John E. Matz (Natick, Massachusetts); Adam Quagliaroli (Windsor Locks, Connecticut); Samuel T. Davidson (Suffield, Connecticut); Herbert A. Chin (Portland, Connecticut) |
| ABSTRACT | A method of repairing a rotor blade, for example on an integrally bladed rotor, includes preparing a surface on a damaged area of the blade. The blade has first and second airfoil surfaces adjoining the prepared surface that are spaced apart a distance. An edge of a patch abuts the prepared surface to provide a weld interface defining a welding plane. First and second cover sheets respectively overlap the first and second airfoil surfaces. The first and second cover sheets adjoin the edge and the first and second airfoil surfaces. The blade, patch and first and second cover sheets are welded along the welding plane providing a welded joint at the weld interface. The first and second cover sheets are substantially unsecured to the first and second airfoil surfaces subsequent to the welding operation. |
| FILED | Wednesday, November 25, 2009 |
| APPL NO | 12/625654 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/229.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616854 | Mahan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vance A. Mahan (Martinsville, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Vance A. Mahan (Martinsville, Indiana) |
| ABSTRACT | A nose cone assembly for a gas turbine engine is disclosed herein. The nose cone assembly includes a spinner body having an outer surface and extending axially between an upstream portion generally tapering to a truncated first end and a base portion generally cylindrical in cross-section at a second end. The nose cone assembly also includes a flange positioned radially inward of the outer surface and axially adjacent to the base portion. The nose cone assembly also includes a plurality of first apertures defined in the flange for removably connecting the spinner body to a fan of a gas turbine engine. The nose cone assembly also includes a second aperture defined in the spinner body through which all of the plurality of first apertures can be accessed for attaching or removing the nose cone assembly from the fan. |
| FILED | Thursday, March 05, 2009 |
| APPL NO | 12/398439 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Fluid reaction surfaces 416/245.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616858 | Rosner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jason E. Rosner (Southington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Jason E. Rosner (Southington, Connecticut) |
| ABSTRACT | A hydraulic system, including fluid flow generated by a primary pump and a secondary pump, utilizes a regulator control assembly to control fluid flow from each of the primary and secondary pumps such that a desired fluid flow and pressure is maintained at the outlet for varying actuator demands. The regulator control assembly controls the transition from using only the primary pump, to using both the primary and secondary pumps to provide a desired fluid flow and pressure through the outlet to the actuator. |
| FILED | Friday, September 09, 2011 |
| APPL NO | 13/229029 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Pumps 417/304 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617326 | Schneider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stefan Schneider (Palmdale, California); Tommy W. Hawkins (Lancaster, California); Michael S. Rosander (Lancaster, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Stefan Schneider (Palmdale, California); Tommy W. Hawkins (Lancaster, California); Michael S. Rosander (Lancaster, California) |
| ABSTRACT | Advanced bipropellant fuels with fast ignition upon mixing with storable oxidizer (N2O4, nitric acid) have been synthesized and demonstrated. The bipropellant fuels are based upon salts containing dicyanamide or tricyanomethanide anions and employ at least two hydrazine functionalities in the cations. |
| FILED | Friday, September 25, 2009 |
| APPL NO | 12/567136 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617328 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ming-Wan Young (Basking Ridge, New Jersey); Costas G. Gogos (Wyckoff, New Jersey); Niloufar Faridi (Melville, New York); Linjie Zhu (Livingston, New Jersey); Peter Bonnett (Succasunna, New Jersey); Howard Shimm (Budd Lake, New Jersey); Elbert Caravaca (Budd Lake, New Jersey); Joseph Palk, Jr. (Ledgewood, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ming-Wan Young (Basking Ridge, New Jersey); Costas G. Gogos (Wyckoff, New Jersey); Niloufar Faridi (Melville, New York); Linjie Zhu (Livingston, New Jersey); Peter Bonnett (Succasunna, New Jersey); Howard Shimm (Budd Lake, New Jersey); Elbert Caravaca (Budd Lake, New Jersey); Joseph Palk, Jr. (Ledgewood, New Jersey) |
| ABSTRACT | An economical, low residue, mortar increment propellant container manufactured of foamed celluloid, which is composed of 50 to 84% nitrocellulose, having a nitrogen content of from about 10.5 to about 13.5%, and about 15 to about 50% camphor. The burn rate of the foamed celluloid can be enhanced by the addition of energetic additives, such as energetic plasticizers. |
| FILED | Friday, June 12, 2009 |
| APPL NO | 12/483420 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/19.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617407 | Hantschel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Hantschel (Menlo Park, California); Noble M. Johnson (Menlo Park, California); Peter Kiesel (Palo Alto, California); Christian G. Van de Walle (Santa Barbara, California); William S. Wong (San Carlos, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Thomas Hantschel (Menlo Park, California); Noble M. Johnson (Menlo Park, California); Peter Kiesel (Palo Alto, California); Christian G. Van de Walle (Santa Barbara, California); William S. Wong (San Carlos, California) |
| ABSTRACT | Systems and methods may provide electrical contacts to an array of substantially vertically aligned nanorods. The nanorod array may be fabricated on top of a conducting layer that serves as a bottom contact to the nanorods. A top metal contact may be applied to a plurality of nanorods of the nanorod array. The contacts may allow I/V (current/voltage) characteristics of the nanorods to be measured. |
| FILED | Monday, April 28, 2008 |
| APPL NO | 12/110899 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Etching a substrate: Processes 216/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617456 | Pechenik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexander Pechenik (Getzville, New York); Wesley P. Hoffman (Palmdale, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Alexander Pechenik (Getzville, New York); Wesley P. Hoffman (Palmdale, California) |
| ABSTRACT | This invention describes a novel type of materials named by the inventors as Interface-Defined nano-Laminates (IDnL), and a new method for fabricating these materials from ceramic, metallic, and other powders. The laminate layer thickness in IDnL is smaller than that of ordinary laminates, but greater than that of superlattices. IDnL are fundamentally different from ordinary laminates in that their properties are defined by interfaces, and not by the properties of the bulk materials comprising individual layers. In contrast to superlattice materials, IDnL can be made thermally stable, due to the wide selection of interface-defining materials, which allows judicial use of equilibrium phase diagrams, and the “entropic stabilization” approach discovered by the authors; and in addition IDnL can be manufactured inexpensively in bulk, industrial quantities and large sizes by the techniques revealed in this invention. The degree of interface coherency in an IDnLs can be varied to optimize material properties. |
| FILED | Wednesday, December 29, 2010 |
| APPL NO | 12/980831 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/650 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617484 | Leung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kimberly Leung (San Diego, California); Charles Ringer (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kimberly Leung (San Diego, California); Charles Ringer (San Diego, California) |
| ABSTRACT | Sensors, such as optical sensors and other sensors used in an aqueous environment are protected from biological contamination by applying a biocide behind a shutter. The shutter is capable of covering a subject portion of the sensor or surrounding mounting surface adjacent the sensor in at least a semi-sealing manner. A well or reservoir forms a chamber in the shutter that is capable of holding a biocide having a limited water solubility and a low environmental toxicity in the aqueous environment, for example, anhydrous iodine crystals. The reservoir is in communication with the portion of the sensor while positioned against the portion of the sensor or surrounding mounting surface adjacent the sensor. |
| FILED | Tuesday, March 30, 2010 |
| APPL NO | 12/749850 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617513 | Ying et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jackie Y. Ying (Winchester, Massachusetts); Javier García-Martínez (Alicante, Spain) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jackie Y. Ying (Winchester, Massachusetts); Javier García-Martínez (Alicante, Spain) |
| ABSTRACT | One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for organic compounds and degradation catalysts for polymers. |
| FILED | Monday, July 20, 2009 |
| APPL NO | 12/505843 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/716 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617547 | Chinnaiyan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arul Chinnaiyan (Plymouth, Michigan); David Beer (Chelsea, Michigan); Guoan Chen (Ann Arbor, Michigan); Xiaoju Wang (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Arul Chinnaiyan (Plymouth, Michigan); David Beer (Chelsea, Michigan); Guoan Chen (Ann Arbor, Michigan); Xiaoju Wang (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer. |
| FILED | Thursday, September 10, 2009 |
| APPL NO | 12/556831 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617548 | Casey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leslie S. Casey (New York, New York) |
| ASSIGNEE(S) | Elusys Therapeutics, Inc. (Pine Brook, New Jersey) |
| INVENTOR(S) | Leslie S. Casey (New York, New York) |
| ABSTRACT | The present invention provides an antibody which binds to B. anthracis with toxin, formulations for administration of such antibodies intramuscularly, and methods of administering such antibodies prophylactically or therapeutically. |
| FILED | Wednesday, March 30, 2011 |
| APPL NO | 13/076082 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617592 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shaoyi Jiang (Redmond, Washington); Zhiqiang Cao (Somerville, Massachusetts); Hong Xue (Pleasanton, California); Lei Zhang (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Zhiqiang Cao (Somerville, Massachusetts); Hong Xue (Pleasanton, California); Lei Zhang (Seattle, Washington) |
| ABSTRACT | Zwitterionic block copolymers and zwitterionic conjugates that advantageously self-assemble into particles, particles assembled from the zwitterionic block copolymers and zwitterionic conjugates, pharmaceutical compositions that include the self-assembled particles, and methods for delivering therapeutic and diagnostic agents using the particles. |
| FILED | Thursday, May 03, 2012 |
| APPL NO | 13/463662 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617661 | Newkirk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph William Newkirk (Rolla, Missouri); Fuewen Frank Liou (Rolla, Missouri); Romy Francis (Bensalem, Pennsylvania) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Joseph William Newkirk (Rolla, Missouri); Fuewen Frank Liou (Rolla, Missouri); Romy Francis (Bensalem, Pennsylvania) |
| ABSTRACT | A method for fabricating a direct metal deposition (DMD) structure having substantially fully forged structural qualities is provided. In various embodiments, the method includes depositing a layer of metallic material onto an existing metallic structure having a microstructure that provides the existing metallic structure with substantially fully forged structural qualities. The DMD layer has a microstructure that provides the DMD layer with non-forged structural qualities. The method additionally includes applying a friction stir process to the deposited DMD layer utilizing a friction stir device such that the deposited DMD layer and at least a DMD affected zone of the existing metallic structure are friction stirred to refine and homogenize the microstructure of the deposited DMD layer and at least the DMD affected zone of the existing metallic structure, thereby producing a non-forged aggregate structure having a microstructure that provides the aggregate structure substantially fully forged structural qualities. |
| FILED | Tuesday, May 25, 2010 |
| APPL NO | 12/787075 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617689 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kuan-Neng Chen (White Plains, New York); Bruce K. Furman (Poughquag, New York); Sampath Purushothaman (Yorktown Heights, New York); David L. Rath (Stormville, New York); Anna W. Topol (Wappingers Falls, New York); Cornelia K. Tsang (Mohegan Lake, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Kuan-Neng Chen (White Plains, New York); Bruce K. Furman (Poughquag, New York); Sampath Purushothaman (Yorktown Heights, New York); David L. Rath (Stormville, New York); Anna W. Topol (Wappingers Falls, New York); Cornelia K. Tsang (Mohegan Lake, New York) |
| ABSTRACT | Bonding of substrates including metal-dielectric patterns on a surface with the metal raised above the dielectric, as well as related structures, are disclosed. One method includes providing a first substrate having a metal-dielectric pattern on a surface thereof; providing a second substrate having a metal-dielectric pattern on a surface thereof; performing a process resulting in the metal being raised above the dielectric; cleaning the metal; and bonding the first substrate to the second substrate. A related structure is also disclosed. The bonding of raised metal provides a strong bonding medium, and good electrical and thermal connections enabling creation of three dimensional integrated structures with enhanced functionality. |
| FILED | Tuesday, April 10, 2012 |
| APPL NO | 13/443418 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617707 | Krauss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Todd D. Krauss (Penfield, New York); Christopher Evans (Rochester, New York); Li Guo (Rockville, Maryland); Jeffrey J. Peterson (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Todd D. Krauss (Penfield, New York); Christopher Evans (Rochester, New York); Li Guo (Rockville, Maryland); Jeffrey J. Peterson (Rochester, New York) |
| ABSTRACT | Disclosed herein are magic size nanoclusters comprising lead and one or more chalcogens. The disclosed magic size nanoclusters have both spectrally narrow fluorescence and ultra-high quantum efficiencies. Further disclosed herein is a method for preparing PbS, PbSe, and PbTe magic size nanoclusters. The yield of magic size nanoclusters can be increased by using anion sources enriched for secondary phosphines. The use of enriched secondary phosphine anion sources also increases the yield of quantum nanostructures. |
| FILED | Tuesday, March 24, 2009 |
| APPL NO | 12/988992 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617839 | Ewert |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Matt Ewert (St. Petersburg, Florida) |
| ABSTRACT | The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4. |
| FILED | Tuesday, March 05, 2013 |
| APPL NO | 13/725944 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617927 | Margomenos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexandros D. Margomenos (Pasadena, California); Miroslav Micovic (Thousand Oaks, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Alexandros D. Margomenos (Pasadena, California); Miroslav Micovic (Thousand Oaks, California) |
| ABSTRACT | A method and apparatus for mounting microelectronic chips to a thermal heat sink. The chips are arranged in a desired configuration with their active faces all facing a common direction and with their active faces defining a common planar surface for all of said chips. A metallic material is applied to the chip, preferably by electroplating to backsides of the chips, the metallic material being electro-formed thereon and making void-free contact with the backsides of the chips. |
| FILED | Tuesday, November 29, 2011 |
| APPL NO | 13/306827 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/112 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618009 | Schanze et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kirk S. Schanze (Gainesville, Florida); Motokatsu Ogawa (Sherman Oaks, California); Jonathan R. Sommer (Gainesville, Florida); David G. Whitten (Albuquerque, New Mexico); Thomas Corbitt (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Kirk S. Schanze (Gainesville, Florida); Motokatsu Ogawa (Sherman Oaks, California); Jonathan R. Sommer (Gainesville, Florida); David G. Whitten (Albuquerque, New Mexico); Thomas Corbitt (Albuquerque, New Mexico) |
| ABSTRACT | Hollow conjugated polyelectrolyte (HCPE) microcapsules contain at least one conjugated polyelectrolyte and at least one other polyelectrolyte of complementary charge and the microcapsule has a hollow core. The conjugated polyelectrolyte is a polymer with a multiplicity of charged repeating units where a portion of the charged repeating units form a pi-conjugated sequence. The complementary polyelectrolyte is a polymer with a complementary charged repeating unit to the charged repeating units of the conjugated polyelectrolyte. The HCPE microcapsules can be formed by successively coating a sacrificial core with alternating layers of complementary polyelectrolytes, at least one of which is a conjugated polyelectrolyte. The sacrificial core can be removed to form the hollow center of a HCPE microcapsule. The HCPE microcapsules can be contacted with a medium containing microbes where the HCPE microcapsules associate with the microbes and efficiently kill the microbes when irradiated with light or other electromagnetic radiation. |
| FILED | Monday, November 09, 2009 |
| APPL NO | 13/128571 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618241 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baoquan Chen (Bothell, Washington); Danliang Jin (Bothell, Washington); Guomin Yu (Bothell, Washington); Hui Chen (Kirkland, Washington); Diyun Huang (Watertown, Massachusetts) |
| ASSIGNEE(S) | GigOptix, Inc. (San Jose, California) |
| INVENTOR(S) | Baoquan Chen (Bothell, Washington); Danliang Jin (Bothell, Washington); Guomin Yu (Bothell, Washington); Hui Chen (Kirkland, Washington); Diyun Huang (Watertown, Massachusetts) |
| ABSTRACT | According to an embodiment, an electro-optic polymer comprises a host polymer and a guest nonlinear optical chromophore having the structure D-π-A, wherein: D is a donor, π is a π-bridge, and A is an acceptor; a bulky substituent group is covalently attached to at least one of D, π, or A; and the bulky substituent group has at least one non-covalent interaction with part of the host polymer that impedes chromophore depoling. |
| FILED | Friday, December 03, 2010 |
| APPL NO | 12/959898 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618330 | Snow |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arthur W Snow (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Arthur W Snow (Alexandria, Virginia) |
| ABSTRACT | A hexafluorodimethylcarbinol terminated compound, method of making it, and a composition of matter are disclosed. The compound may have the formula (CF3)2C(OH)-L-M-R. The substructure L may be selected from an optionally substituted propenylene group (—CH2CH═CH—) and trimethylene group (—CH2CH2CH2—). The substructure M may be selected from a substituted or unsubstituted methylene chain, a substituted or unsubstituted oxyalkylene chain, and a silicon-containing chain or combination thereof. In one embodiment, M may be selected from —(CH2)n—, —(OCH2CH2)m—, and —(Si(CH3)2O)p—Si(CH3)2—(CH2)q—, wherein n is at least 1, e.g., n is up to 10, m can be at least 1, e.g., m is up to 10, p can be 0 and in one embodiment is from 1 to 10, and wherein q can be 1 and in one embodiment is from 1 to 12. The substructure R represents one of a halogen, —SH, —SZ, —S—S-M-L-C(CF3)2(OH), wherein Z represents a thiol protecting group. |
| FILED | Thursday, August 27, 2009 |
| APPL NO | 12/549177 |
| ART UNIT | 4154 — Organic Chemistry |
| CURRENT CPC | Organic compounds 568/65 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618485 | Lockhart |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Patric K. Lockhart (Middletown, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Patric K. Lockhart (Middletown, Rhode Island) |
| ABSTRACT | A method for detecting suspended discontinuity densities in a material is provided. The method includes transmitting terahertz electromagnetic radiation toward a surface of the material. This radiation is received at an expected location after interacting with the material. The power level of the received radiation is measured and deviation from the expected value is used to determine a suspended discontinuity density gradient in the material. The method can be used with either reflected radiation or transmitted radiation. Embodiments of the method can calculate the index of refraction in the material and correlate this with the suspended discontinuity density of the material. |
| FILED | Friday, September 23, 2011 |
| APPL NO | 13/242441 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/341.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618552 | Powell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Adrian Powell (Cary, North Carolina); Mark Brady (Carrboro, North Carolina); Robert Tyler Leonard (Raleigh, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Adrian Powell (Cary, North Carolina); Mark Brady (Carrboro, North Carolina); Robert Tyler Leonard (Raleigh, North Carolina) |
| ABSTRACT | A high quality single crystal wafer of SiC is disclosed having a diameter of at least about 100 mm and a micropipe density of less than about 25 cm−2. |
| FILED | Thursday, November 15, 2007 |
| APPL NO | 11/940423 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/77 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618553 | Carter, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Calvin H. Carter, Jr. (Durham, North Carolina); Jason R. Jenny (Wake Forest, North Carolina); David P. Malta (Raleigh, North Carolina); Hudson M. Hobgood (Pittsboro, North Carolina); Valeri F. Tsvetkov (Durham, North Carolina); Mrinal K. Das (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Calvin H. Carter, Jr. (Durham, North Carolina); Jason R. Jenny (Wake Forest, North Carolina); David P. Malta (Raleigh, North Carolina); Hudson M. Hobgood (Pittsboro, North Carolina); Valeri F. Tsvetkov (Durham, North Carolina); Mrinal K. Das (Durham, North Carolina) |
| ABSTRACT | A process is described for producing silicon carbide crystals having increased minority carrier lifetimes. The process includes the steps of heating and slowly cooling a silicon carbide crystal having a first concentration of minority carrier recombination centers such that the resultant concentration of minority carrier recombination centers is lower than the first concentration. |
| FILED | Monday, August 30, 2010 |
| APPL NO | 12/871095 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/77 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618736 | Dayton, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James A. Dayton, Jr. (Cleveland, Ohio); Carol L. Kory (Westlake, Ohio) |
| ASSIGNEE(S) | Manhattan Technologies Ltd. (Richmond Heights, Ohio) |
| INVENTOR(S) | James A. Dayton, Jr. (Cleveland, Ohio); Carol L. Kory (Westlake, Ohio) |
| ABSTRACT | Disclosed herein is a class of mm and sub mm wavelength amplifiers and oscillators operating with miniature helical slow wave circuits manufactured using micro fabrication technology. The helices are supported by diamond dielectric support rods. Diamond is the best possible thermal conductor, and it can be bonded to the helix. The electron beam is transmitted, not through the center of the helix, but around the outside. In some configurations the RF power produced may be radiated directly from the slow wave circuit. The method of fabrication, which is applicable above 60 GHz, is compatible with mass production. |
| FILED | Thursday, March 22, 2012 |
| APPL NO | 13/427258 |
| ART UNIT | 2821 — Electrical Circuits and Systems |
| CURRENT CPC | Electric lamp and discharge devices: Systems 315/39.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618966 | Kanter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gregory S. Kanter (Chicago, Illinois); Daniel Reilly (Chicago, Illinois) |
| ASSIGNEE(S) | Nucript LLC (Evanston, Illinois) |
| INVENTOR(S) | Gregory S. Kanter (Chicago, Illinois); Daniel Reilly (Chicago, Illinois) |
| ABSTRACT | A method of digitizing an analog electrical signal combines optical and electronic techniques in order to improve the resolution, sampling rate, input frequency range, or flexibility. It implements an optical interferometric modulator, which modulates an input optical signal by the input electrical signal combined with a calibration signal. A set of two or more photoreceivers receiving the output optical signals from the optical modulator produce output electrical signals, which are digitized and processed in a DSP to produce a digitized version of the electrical input signal, and a digitized calibration signal value is used to optimize the input electrical signal digitization. The method and the device can be used in many fields including instrumentation, communications, and imaging. |
| FILED | Monday, February 20, 2012 |
| APPL NO | 13/400324 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Coded data generation or conversion 341/137 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619237 | Hillman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Matthew B. Bouchard (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Matthew B. Bouchard (New York, New York) |
| ABSTRACT | Laser-Scanning Intersecting Plane Tomography (L-SIPT) can provide a non-contact imaging geometry that can allow high speed volumetric scanning, such as of non-scattering to moderately scattering tissues. The L-SIPT imaging apparatus can include a first lens, located and configured to receive from a sample light received from different depths of the sample. A first light redirector can be located and configured to receive via the first lens and to redirect light received from the different depths of the sample to provide redirected light to a light detector capable of detecting individual measurements of light at different locations along a first direction. A second light redirector can be located and configured to redirect light received from a light source to provide redirected light to the sample, wherein the second light redirector is in a specified spatial relationship to the first light redirector, and wherein the first and second light redirectors are configured to be adjusted during a scan of the sample so as to provide the specified spatial relationship during the scan. |
| FILED | Monday, December 06, 2010 |
| APPL NO | 12/961074 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619261 | Parks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Allen D. Parks (Spotsylvania, Virginia); Scott E. Spence (Fredericksburg, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Allen D. Parks (Spotsylvania, Virginia); Scott E. Spence (Fredericksburg, Virginia) |
| ABSTRACT | A quantum dynamical non-locality device is provided for establishing a photon traveling along a path in a binary state. The device includes twin Mach-Zehnder interferometer (MZI), a shutter and a detector. The twin MZI includes first and second right-isosceles triangle prisms, corresponding first and second trombone mirrors, and corresponding first and second spacers. The prisms join at a beam-splitter interface. The mirrors reflect the photon by an offset substantially perpendicular to photon's travel direction. The spacers are respectively disposed between their respective prisms and mirrors to produce corresponding spatial gaps. The path through the prisms includes traversing spacers and gaps. The detector detects a quantum state of the photon after passing the prisms and the mirrors. The shutter switches to one of disposed within and removed therefrom the first gap. The shutter shifts said quantum state of the photon. |
| FILED | Wednesday, August 24, 2011 |
| APPL NO | 13/199507 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619356 | Weyburne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Weyburne (Maynard, Massachusetts); David Bliss (Arlington, Massachusetts); Candace Lynch (Chelmsford, Massachusetts) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | David Weyburne (Maynard, Massachusetts); David Bliss (Arlington, Massachusetts); Candace Lynch (Chelmsford, Massachusetts) |
| ABSTRACT | A new method for making a nonlinear optical structure for frequency conversion and for using that structure for frequency conversion is described. The nonlinear optical structure is made by depositing alternating contiguous layers of gallium arsenide and aluminum gallium arsenide onto a gallium arsenide substrate. Optical frequency conversion is performed by transmitting a pump laser beam through the structure. The new method is easier to perform than prior art methods. |
| FILED | Wednesday, March 07, 2012 |
| APPL NO | 13/414370 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/332 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619358 | Kimerling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lionel C. Kimerling (Concord, Massachusetts); Harry Atwater (South Pasadena, California); Mark L. Brongersma (Redwood City, California); Luca Dal Negro (Cambridge, Massachusetts); Thomas L Koch (Califon, New Jersey); Philippe Fauchet (Pittsford, New York); Michal Lipson (Ithaca, New York); Jurgen Michel (Arlington, Massachusetts); Carlos Angulo Barrios (Madrid, Spain) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); University of Rochester (Rochester, New York); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Lionel C. Kimerling (Concord, Massachusetts); Harry Atwater (South Pasadena, California); Mark L. Brongersma (Redwood City, California); Luca Dal Negro (Cambridge, Massachusetts); Thomas L Koch (Califon, New Jersey); Philippe Fauchet (Pittsford, New York); Michal Lipson (Ithaca, New York); Jurgen Michel (Arlington, Massachusetts); Carlos Angulo Barrios (Madrid, Spain) |
| ABSTRACT | An optical amplifier on a silicon platform includes a first doped device layer and a second doped device layer. A gain medium is positioned between the first and second doped device layers. The gain medium comprises extrinsic gain materials so as to substantially confine in the gain medium a light signal and allow the optical amplifier to be electrically or optically pumped. |
| FILED | Tuesday, November 03, 2009 |
| APPL NO | 12/611435 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/344 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619417 | Helton |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Justin R. Helton (Fredericksburg, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Justin R. Helton (Fredericksburg, Virginia) |
| ABSTRACT | A computer docking station is provided having an enclosure unit, a cable-to-panel connector, a dock cover, an electrical connector that includes an open box configuration; and a cable-to-panel component. The enclosure unit connects to the docking station. The dock cover is disposed inside the enclosure unit. The electrical connector is also disposed inside the enclosure unit and connects to the dock cover. The electrical connector comprises connectors to enable electrical connections to peripheral devices, a mounting plate positioned over the enclosure unit, a docking connector operatively connected to the dock cover and extending through the mounting plate, and a plurality of gaskets connected to the mounting plate. |
| FILED | Tuesday, November 08, 2011 |
| APPL NO | 13/373243 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/679.410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619792 | Gallimore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ian Gallimore (Palmyra, Pennsylvania); Jared Scott Marmen (Bel Air, Maryland) |
| ASSIGNEE(S) | Coherent Technical Services, Inc. (Lexington Park, Maryland) |
| INVENTOR(S) | Ian Gallimore (Palmyra, Pennsylvania); Jared Scott Marmen (Bel Air, Maryland) |
| ABSTRACT | System and methods for an interface alteration device that recognizes in incoming data whether certain predefined conditions exist based on condition evaluation rules, and, as appropriate, alters certain portions of the incoming data based on alteration rules. Transmission tolerance levels also define how transmission of data is to be performed so that the destination node to which the altered and/or unaltered data is transmitted will be unaware that alteration has occurred to the data stream. |
| FILED | Tuesday, January 13, 2009 |
| APPL NO | 12/352728 |
| ART UNIT | 2477 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619832 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Qing Hu (Wellesley, Massachusetts); Alan Wei Min Lee (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Qing Hu (Wellesley, Massachusetts); Alan Wei Min Lee (Boston, Massachusetts) |
| ABSTRACT | Terahertz quantum cascade (QC) devices are disclosed that can operate, e.g., in a range of about 1 THz to about 10 THz. In some embodiments, QC lasers are disclosed in which an optical element (e.g., a lens) is coupled to an output facet of the laser's active region to enhance coupling of the lasing radiation from the active region to an external environment. In other embodiments, terahertz amplifier and tunable terahertz QC lasers are disclosed. |
| FILED | Friday, May 08, 2009 |
| APPL NO | 12/437818 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/50.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620069 | Pinkus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan R. Pinkus (Bellbrook, Ohio); David W. Dommett (Beavercreek, Ohio); Harry Lee Task (Tucson, Arizona) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Alan R. Pinkus (Bellbrook, Ohio); David W. Dommett (Beavercreek, Ohio); Harry Lee Task (Tucson, Arizona) |
| ABSTRACT | A method, apparatus and program product are presented for detecting an image. Ring contour images are created by blurring the image, posterizing the blurred image at a plurality of levels and creating the ring contour images from each of the posterized images. Convex hull images are created by creating a plurality of corner images from corners within the image located by at least two different corner algorithms, finding a bounding rectangle that encompasses the ring contour images, cropping the corner images using the bounding rectangle, applying a threshold to the cropped corner images, and creating the convex hull images by generating a convex hull from the corners in each of the cropped corner images. A plurality of triangles is created by fitting a triangle with an orientation to the ring contour images and the convex hull images. Finally the orientation of the triangle is determined from the plurality of triangles. |
| FILED | Friday, February 11, 2011 |
| APPL NO | 13/025570 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/165 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620082 | Cobb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James T. Cobb (Panama City, Florida); Gerald J. Dobeck (Panama City, Florida) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James T. Cobb (Panama City, Florida); Gerald J. Dobeck (Panama City, Florida) |
| ABSTRACT | Systems and methods for sonar image feature extraction, which fit a parameterized statistical model to sonar image data to extract features that describe image textures for follow-on pattern classification tasks. The systems and methods estimate the parameters of an assumed statistical model from the pixel values in the sonar images. The parameters of the distribution can then be used as features in a discriminant classifier to perform tasks such as texture segmentation or environmental characterization. The systems and methods divide a sonar image into separate overlapping cells. The ACF parameters of each cell are sequentially estimated using various methods. Based on the ACF parameters obtained, each cell is assigned a label via a pattern classification algorithm. The labeled image can be used in target recognition, environmental characterization and texture segmentation. |
| FILED | Friday, April 01, 2011 |
| APPL NO | 13/066230 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/181 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620089 | Korah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thommen Korah (Marina Del Rey, California); Swarup S. Medasani (Thousand Oaks, California); Yuri Owechko (Newbury Park, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Thommen Korah (Marina Del Rey, California); Swarup S. Medasani (Thousand Oaks, California); Yuri Owechko (Newbury Park, California) |
| ABSTRACT | A method of recognizing features in a 3D environment includes using a sensor that collects a plurality of sensed data points, populating a strip histogram grid having a plurality of strips, each strip having a dx dimension and a dy dimension, by assigning each sensed data point to a strip in the strip histogram grid that has x, y and z dimensions that encompass the spatial coordinate information of the respective assigned sensed data point, and estimating the local ground plane for a strip in the strip histogram grid by using information on each sensed data point assigned to that strip and surrounding strips in the strip histogram grid. Further methods include extracting smooth surfaces, building segmentation, top down segmentation and bottom up segmentation. |
| FILED | Tuesday, December 22, 2009 |
| APPL NO | 12/644349 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/195 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620093 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lam Huy Nguyen (Laurel, Maryland); Trac D Tran (Columbia, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Lam Huy Nguyen (Laurel, Maryland); Trac D Tran (Columbia, Maryland) |
| ABSTRACT | A system and method for detecting changes by comparing images which cover the same physical area but are collected at different times, the system comprising: at least one input for inputting an image of a target area; the image of the target area having signatures representing outstanding features; at least one processor operating to divide the image of a target area into a plurality of target subimages; at least one memory comprising reference data comprising reference subimages taken at or near the target area at various times, the at least one processor operating to determine a sparse image representation from the reference data; the sparse image representation of the target data being a linear combination of reference data from corresponding reference subimages stored in the at least one memory; the at least one processor operating to compare the target image to the sparse image representation and to match signatures from the target image to the sparse image representation to register the images and perform change detection. |
| FILED | Tuesday, October 19, 2010 |
| APPL NO | 12/907496 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/218 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620166 | Guha |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Saikat Guha (Everett, Massachusetts) |
| ASSIGNEE(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| INVENTOR(S) | Saikat Guha (Everett, Massachusetts) |
| ABSTRACT | An optical receiver may include a unitary transformation operator to receive an n-symbol optical codeword associated with a codebook, and to perform a unitary transformation on the received optical codeword to generate a transformed optical codeword, where the unitary transformation is based on the codebook. The optical receiver may further include n optical detectors, where a particular one of the n optical detectors is to detect a particular optical symbol of the transformed optical codeword, and to determine whether the particular optical symbol corresponds to a first optical symbol or a second optical symbol. The optical receiver may also include a decoder to construct a codeword based on the determinations, and to decode the constructed codeword into a message using the codebook. The optical receiver may attain superadditive capacity, and, with an optimal code, may attain the Holevo limit to reliable communication data rates. |
| FILED | Wednesday, November 30, 2011 |
| APPL NO | 13/307439 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Optical communications 398/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620464 | Weiland |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher J. Weiland (King George, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher J. Weiland (King George, Virginia) |
| ABSTRACT | A visual automated score system (VASS) is provided to enable computerized accuracy assessment of weapons systems through video photography. Images are fed into a computer which tracks the intended target, detects impact points and then provides human operators with an automatically computed miss distance based on the cross-correlation of at least two video images. The VASS may then provide feedback to the weapons system to correct and direct gunfire. |
| FILED | Tuesday, February 07, 2012 |
| APPL NO | 13/385473 |
| ART UNIT | 3717 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/92 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620620 | Yuen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Keith Ng Yuen (Pasadena, California); Alex Phi Bao Long Nguyen (Oxnard, California); David George Omoto (Camarillo, California); Jacob B. Oliver (Port Hueneme, California); Michael Anthony Antonio Pascual (Camarillo, California); Sean Xiao-Yun Hong (Ventura, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Keith Ng Yuen (Pasadena, California); Alex Phi Bao Long Nguyen (Oxnard, California); David George Omoto (Camarillo, California); Jacob B. Oliver (Port Hueneme, California); Michael Anthony Antonio Pascual (Camarillo, California); Sean Xiao-Yun Hong (Ventura, California) |
| ABSTRACT | A method(s) of testing AN/ULQ-21 (Hydra) Circuit Card Assembly(ies) (CCAs), which involve providing software to perform automated tests on Hydra CCAs that make up the Hydra Countermeasures Set and employ commercial off the shelf equipment (such as signal generators, spectrum analyzer, Data Acquisition Device(s), oscillators, etc. as applicable depending on the test and CCA being evaluated). |
| FILED | Thursday, September 30, 2010 |
| APPL NO | 12/895718 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620660 | Yen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anton Yen (San Diego, California); Irina Gorodnitsky (San Diego, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Anton Yen (San Diego, California); Irina Gorodnitsky (San Diego, California) |
| ABSTRACT | Improved oscillator-based source modeling methods for estimating model parameters, for evaluating model quality for restoring the input from the model parameters, and for improving performance over known in the art methods are disclosed. An application of these innovations to speech coding is described. The improved oscillator model is derived from the information contained in the current input signal as well as from some form of data history, often the restored versions of the earlier processed data. Operations can be performed in real time, and compression can be achieved at a user-specified level of performance and, in some cases, without information loss. The new model can be combined with methods in the existing art in order to complement the properties of these methods, to improve overall performance. The present invention is effective for very low bit-rate coding/compression and decoding/decompression of digital signals, including digitized speech and audio signals. |
| FILED | Friday, October 29, 2010 |
| APPL NO | 12/915989 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/258 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620961 | Ittycheriah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Abraham Ittycheriah (Brookfield, Connecticut); Hongyan Jing (White Plains, New York); Nandakishore Kambhatla (White Plains, New York); Xiaoqiang Luo (Ardsley, New York); Salim E. Roukos (Scarsdale, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Abraham Ittycheriah (Brookfield, Connecticut); Hongyan Jing (White Plains, New York); Nandakishore Kambhatla (White Plains, New York); Xiaoqiang Luo (Ardsley, New York); Salim E. Roukos (Scarsdale, New York) |
| ABSTRACT | A Bell Tree data structure is provided to model the process of chaining the mentions, from one or more documents, into entities, tracking the entire process; where the data structure is used in an entity tracking process that produces multiple results ranked by a product of probability scores. |
| FILED | Monday, May 05, 2008 |
| APPL NO | 12/115321 |
| ART UNIT | 2155 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Database and file management or data structures 77/797 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08621238 | Kimball |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William B Kimball (Dayton, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | William B Kimball (Dayton, Ohio) |
| ABSTRACT | An apparatus, method and program product are provided for securing a computer system. A digital signature of an application is checked, which is loaded into a memory of the computer system configured to contain memory pages. In response to finding a valid digital signature, memory pages containing instructions of the application are set as executable and memory pages other than those containing instructions of the application are set as non-executable. Instructions in executable memory pages are executed. Instructions in non-executable memory pages are prevented from being executed. A page fault is generated in response to an attempt to execute an instruction in a non-executable memory page. In response to the page fault, an exception list of a sequence of instructions is checked for the attempted instruction in the non-executable memory page and if on the list, the page is set to executable and the attempted instruction executed. |
| FILED | Tuesday, July 26, 2011 |
| APPL NO | 13/190520 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08621277 | Carey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James E. Carey (Rochester, Minnesota); Matthew W. Markland (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | James E. Carey (Rochester, Minnesota); Matthew W. Markland (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota) |
| ABSTRACT | Methods, systems and products are provided for dynamic administration of component event reporting in a distributed processing system including receiving, by an events analyzer from an events queue, a plurality of events from one or more components of the distributed processing system; determining, by the events analyzer in dependence upon the received events and one or more event analysis rules, to change the event reporting rules of one or more components; and instructing, by the events analyzer, the one or more components to change the event reporting rules. |
| FILED | Monday, December 06, 2010 |
| APPL NO | 12/960990 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08621610 | Oberheide et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jon Oberheide (Troy, Michigan); Evan Cooke (Cambridge, Massachusetts); Farnam Jahanian (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Jon Oberheide (Troy, Michigan); Evan Cooke (Cambridge, Massachusetts); Farnam Jahanian (Ann Arbor, Michigan) |
| ABSTRACT | A system is provided for detecting, analyzing and quarantining unwanted files in a network environment. A host agent residing on a computing device in the network environment detects a new file introduced to the computing device and sends the new file to a network service for analysis. The network service is accessible to computing devices in the network environment. An architecture for the network service may include: a request dispatcher configured to receive a candidate file for inspection from a given computing device in the network environment and distribute the candidate file to one or more of a plurality of detection engines, where the detection engines operate in parallel to analyze the candidate file and output a report regarding the candidate file; and a result aggregator configured to receive reports from each of the detection engines regarding the candidate file and aggregates the reports in accordance with an aggregation algorithm. |
| FILED | Tuesday, August 05, 2008 |
| APPL NO | 12/186014 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Information security 726/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08615812 | Wójtowicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marek A. Wójtowicz (East Hartford, Connecticut); Eric P. Rubenstein (Longmeadow, Massachusetts); Michael A. Serio (Sturbridge, Massachusetts); Joseph E. Cosgrove (Columbia, Connecticut) |
| ASSIGNEE(S) | Advanced Fuel Research, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Marek A. Wójtowicz (East Hartford, Connecticut); Eric P. Rubenstein (Longmeadow, Massachusetts); Michael A. Serio (Sturbridge, Massachusetts); Joseph E. Cosgrove (Columbia, Connecticut) |
| ABSTRACT | High-strength porous carbon and a method of its manufacture are described for multifunctional applications, such as ballistic protection, structural components, ultracapacitor electrodes, gas storage, and radiation shielding. The carbon is produced from a polymer precursor via carbonization, and optionally by surface activation and post-treatment. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 12/798218 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparel 02/2.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08615941 | Botkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SunPower Corporation (San Jose, California) |
| ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
| INVENTOR(S) | Jonathan Botkin (El Cerrito, California); Simon Graves (Berkeley, California); Matt Danning (Oakland, California); Matthew Culligan (Berkeley, California) |
| ABSTRACT | A PV module kit for non-penetrating rooftop installation, including a plurality of PV modules and a plurality of connectors. Each of the PV modules includes a PV laminate and a frame forming a mounting region assembled thereto. The connectors include a male connector having a male fastener extending from a head, and a female connector having a female fastener assembled within a head. The heads are entirely formed of plastic. The kit provides a mounted array state including a junction at which the mounting region of at least two of the PV modules are aligned and interconnected by engagement of the male connector with the female connector. The so-formed junction is substantially electrically insulated. The plurality of connectors can further include a spacer connector including a head forming a bore sized to slidably receive the male fastener, with all of the connector heads being identical. |
| FILED | Friday, September 21, 2012 |
| APPL NO | 13/624521 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Static structures 052/173.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08615988 | Gonze et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eugene V. Gonze (Pinckney, Michigan); Frank Ament (Troy, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (, None) |
| INVENTOR(S) | Eugene V. Gonze (Pinckney, Michigan); Frank Ament (Troy, Michigan) |
| ABSTRACT | An exhaust system that processes exhaust generated by an engine includes a diesel particulate filter (DPF) that is disposed downstream of the engine and that filters particulates from the exhaust. An electrical heater is disposed upstream of the DPF and selectively heats the exhaust to initiate combustion of the particulates within the exhaust as it passes therethrough. Heat generated by combustion of the particulates induces combustion of particulates within the DPF. |
| FILED | Tuesday, August 23, 2005 |
| APPL NO | 11/209427 |
| ART UNIT | 3748 — Static Structures, Supports and Furniture |
| CURRENT CPC | Power plants 060/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616002 | Kraemer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gilbert Otto Kraemer (Greer, South Carolina); Balachandar Varatharajan (Loveland, Ohio); Andrei Tristan Evulet (Clifton Park, New York); Ertan Yilmaz (Glenville, New York); Benjamin Paul Lacy (Greer, South Carolina) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Gilbert Otto Kraemer (Greer, South Carolina); Balachandar Varatharajan (Loveland, Ohio); Andrei Tristan Evulet (Clifton Park, New York); Ertan Yilmaz (Glenville, New York); Benjamin Paul Lacy (Greer, South Carolina) |
| ABSTRACT | Methods and systems are provided for premixing combustion fuel and air within gas turbines. In one embodiment, a combustor includes an upstream mixing panel configured to direct compressed air and combustion fuel through a premixing zone to form a fuel-air mixture. The combustor also includes a downstream mixing panel configured to mix additional combustion fuel with the fuel-air mixture to form a combustion mixture. |
| FILED | Thursday, July 23, 2009 |
| APPL NO | 12/508545 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/737 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616044 | Yashchuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Valeriy V. Yashchuk (Richmond, California); Wayne R. McKinney (Concord, California); Peter Z. Takacs (Riverhead, New York) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Valeriy V. Yashchuk (Richmond, California); Wayne R. McKinney (Concord, California); Peter Z. Takacs (Riverhead, New York) |
| ABSTRACT | The present invention provides for test surfaces and methods for calibration of surface profilometers, including interferometric and atomic force microscopes. Calibration is performed using a specially designed test surface, or the Binary Pseudo-random (BPR) grating (array). Utilizing the BPR grating (array) to measure the power spectral density (PSD) spectrum, the profilometer is calibrated by determining the instrumental modulation transfer function (IMTF). |
| FILED | Friday, March 20, 2009 |
| APPL NO | 12/408508 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/1.890 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616177 | Reitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolf Deneys Reitz (Madison, Wisconsin); Reed M. Hanson (Madison, Wisconsin); Derek A. Splitter (Madison, Wisconsin); Sage L. Kokjohn (Fitchburg, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Rolf Deneys Reitz (Madison, Wisconsin); Reed M. Hanson (Madison, Wisconsin); Derek A. Splitter (Madison, Wisconsin); Sage L. Kokjohn (Fitchburg, Wisconsin) |
| ABSTRACT | A compression ignition engine uses two or more fuel charges having two or more reactivities to control the timing and duration of combustion. In a preferred implementation, a lower-reactivity fuel charge is injected or otherwise introduced into the combustion chamber, preferably sufficiently early that it becomes at least substantially homogeneously dispersed within the chamber before a subsequent injection is made. One or more subsequent injections of higher-reactivity fuel charges are then made, and these preferably distribute the higher-reactivity matter within the lower-reactivity chamber space such that combustion begins in the higher-reactivity regions, and with the lower-reactivity regions following thereafter. By appropriately choosing the reactivities of the charges, their relative amounts, and their timing, combustion can be tailored to achieve optimal power output (and thus fuel efficiency), at controlled temperatures (and thus controlled NOx), and with controlled equivalence ratios (and thus controlled soot). |
| FILED | Thursday, February 11, 2010 |
| APPL NO | 12/703808 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/304 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616237 | Jansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John F. Jansen (Knoxville, Tennessee); Lonnie J. Love (Knoxville, Tennessee); Randall F. Lind (Loudon, Tennessee); Bradley S. Richardson (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | John F. Jansen (Knoxville, Tennessee); Lonnie J. Love (Knoxville, Tennessee); Randall F. Lind (Loudon, Tennessee); Bradley S. Richardson (Knoxville, Tennessee) |
| ABSTRACT | A mesofluidic scale digital valve system includes a first mesofluidic scale valve having a valve body including a bore, wherein the valve body is configured to cooperate with a solenoid disposed substantially adjacent to the valve body to translate a poppet carried within the bore. The mesofluidic scale digital valve system also includes a second mesofluidic scale valve disposed substantially perpendicular to the first mesofluidic scale valve. The mesofluidic scale digital valve system further includes a control element in communication with the solenoid, wherein the control element is configured to maintain the solenoid in an energized state for a fixed period of time to provide a desired flow rate through an orifice of the second mesofluidic valve. |
| FILED | Thursday, February 03, 2011 |
| APPL NO | 13/020626 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/624.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616404 | Starck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Starck (Grand Rapids, Michigan); Lou Wordelman (Grand Rapids, Michigan); Paul S. Blanton (Aiken, South Carolina); Kurt R. Eberl (Aiken, South Carolina) |
| ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina); Paragon D and E (Grand Rapids, Michigan) |
| INVENTOR(S) | Robert Starck (Grand Rapids, Michigan); Lou Wordelman (Grand Rapids, Michigan); Paul S. Blanton (Aiken, South Carolina); Kurt R. Eberl (Aiken, South Carolina) |
| ABSTRACT | A shipping container for enclosing a material container containing nuclear and/or other hazardous material. The shipping container can include a body having an open top and a lid assembly for closing the open top. The body can include a liner arranged in spaced relationship with the body to define a space therebetween. The lid assembly and the body can together define a storage chamber in which the material container is housed. The lid assembly can have a lid top and a lid liner coupled to the lid top to define a space therebetween. The space in the lid assembly can also include one or more reinforcing members to increase the compression strength of the lid assembly. The spaces in the body and lid assembly can be filled with a liner material, such as foam, to increase stiffness. |
| FILED | Thursday, June 02, 2011 |
| APPL NO | 13/151733 |
| ART UNIT | 3788 — Electrical Circuits and Systems |
| CURRENT CPC | Receptacles 220/592.250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617372 | West et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Lawrence West (Oak Ridge, Tennessee); Frederick Charles Montgomery (Oak Ridge, Tennessee); Timothy R. Armstrong (Clinton, Tennessee); Robert J. Warmack (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | David Lawrence West (Oak Ridge, Tennessee); Frederick Charles Montgomery (Oak Ridge, Tennessee); Timothy R. Armstrong (Clinton, Tennessee); Robert J. Warmack (Knoxville, Tennessee) |
| ABSTRACT | An array-type sensor that senses NH3 includes non-Nernstian sensing elements constructed from metal and/or metal-oxide electrodes on an O2 ion conducting substrate. In one example sensor, one electrode may be made of platinum, another electrode may be made of manganese (III) oxide (Mn2O3), and another electrode may be made of tungsten trioxide (WO3). Some sensing elements may further include an electrode made of La0.6Sr0.4Co0.2Fe0.8O3 and another electrode made of LaCr0.95Mg0.05O3. |
| FILED | Friday, March 11, 2011 |
| APPL NO | 13/046412 |
| ART UNIT | 1756 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/421 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617499 | Siriwardane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ranjani V. Siriwardane (Morgantown, West Virginia); James C. Fisher, II (Morgantown, West Virginia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Ranjani V. Siriwardane (Morgantown, West Virginia); James C. Fisher, II (Morgantown, West Virginia) |
| ABSTRACT | The disclosure utilizes a hydroxide sorbent for humidification and CO2 removal from a gaseous stream comprised of CO and CO2 prior to entry into a water-gas-shift reactor, in order to decrease CO2 concentration and increase H2O concentration and shift the water-gas shift reaction toward the forward reaction products CO2 and H2. The hydroxide sorbent may be utilized for absorption of CO2 exiting the water-gas shift reactor, producing an enriched H2 stream. The disclosure further provides for regeneration of the hydroxide sorbent at temperature approximating water-gas shift conditions, and for utilizing H2O product liberated as a result of the CO2 absorption. |
| FILED | Wednesday, September 22, 2010 |
| APPL NO | 12/887827 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/225 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617765 | Roelofs |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark Gerrit Roelofs (Earleville, Maryland) |
| ASSIGNEE(S) | E I du Pont de Nemours and Company (Wilmington, Delaware) |
| INVENTOR(S) | Mark Gerrit Roelofs (Earleville, Maryland) |
| ABSTRACT | Ionomeric polymers that are chemically stabilized and contain inorganic fillers are prepared, and show reduced degradation. The ionomers care useful in membranes and electrochemical cells. |
| FILED | Thursday, December 21, 2006 |
| APPL NO | 12/158098 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/494 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617856 | Pfleger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian F. Pfleger (Madison, Wisconsin); Rebecca M. Lennen (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Rebecca M. Lennen (Madison, Wisconsin) |
| ABSTRACT | Described are hosts for overproducing a fatty acid product such as a fatty acid. The hosts include an exogenous nucleic acid encoding a thioesterase and, optionally, an exogenous nucleic acid encoding an acetyl-CoA carboxylase, wherein an acyl-CoA synthetase in the hosts are functionally deleted. The hosts preferably include the nucleic acid encoding the thioesterase at an intermediate copy number. The hosts are preferably recombinantly stable and growth-competent at 37° C. Methods of producing a fatty acid product comprising culturing such hosts at 37° C. are also described. |
| FILED | Tuesday, January 04, 2011 |
| APPL NO | 12/984343 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617869 | Culver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James N. Culver (Potomac, Maryland); Michael Harris (Lafayette, Indiana); Elizabeth Royston (Columbia, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | James N. Culver (Potomac, Maryland); Michael Harris (Lafayette, Indiana); Elizabeth Royston (Columbia, Maryland) |
| ABSTRACT | The present invention relates to high content surface areas containing nickel and/or cobalt metallic compounds assembled on a modified Tobacco mosaic virus (TMV) template, wherein the modified TMV template is engineered to encode unique placement of cysteine residues that self-assemble onto gold patterned surfaces in a substantially aligned fashion, producing a >10 fold increase in surface area. Deposition of ionic metals onto the surface assembled virus templates produce uniform metal coatings for the fabrication of oriented high surface area materials. |
| FILED | Friday, December 28, 2007 |
| APPL NO | 12/520968 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617909 | Batres et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Max Batres (Santa Barbara, California); James Ibbetson (Santa Barbara, California); Ting Li (Ventura, California); Adam W. Saxler (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Goleta, California) |
| INVENTOR(S) | Max Batres (Santa Barbara, California); James Ibbetson (Santa Barbara, California); Ting Li (Ventura, California); Adam W. Saxler (Durham, North Carolina) |
| ABSTRACT | The surface morphology of an LED light emitting surface is changed by applying a reactive ion etch (RIE) process to the light emitting surface. Etched features, such as truncated pyramids, may be formed on the emitting surface, prior to the RIE process, by cutting into the surface using a saw blade or a masked etching technique. Sidewall cuts may also be made in the emitting surface prior to the RIE process. A light absorbing damaged layer of material associated with saw cutting is removed by the RIE process. The surface morphology created by the RIE process may be emulated using different, various combinations of non-RIE processes such as grit sanding and deposition of a roughened layer of material or particles followed by dry etching. |
| FILED | Wednesday, April 01, 2009 |
| APPL NO | 12/384277 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618495 | De Geronimo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gianluigi De Geronimo (Syosset, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Gianluigi De Geronimo (Syosset, New York) |
| ABSTRACT | A method and apparatus for pulse pile-up rejection are disclosed. The apparatus comprises a delay value application constituent configured to receive a threshold-crossing time value, and provide an adjustable value according to a delay value and the threshold-crossing time value; and a comparison constituent configured to receive a peak-occurrence time value and the adjustable value, compare the peak-occurrence time value with the adjustable value, indicate pulse acceptance if the peak-occurrence time value is less than or equal to the adjustable value, and indicate pulse rejection if the peak-occurrence time value is greater than the adjustable value. |
| FILED | Monday, May 02, 2011 |
| APPL NO | 13/098949 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/395 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618708 | Van Dam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeremy Daniel Van Dam (West Coxsackie, New York); James Pellegrino Alexander (Ballston Lake, New York); Murtuza Yusuf Lokhandwalla (Canton, Michigan) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Jeremy Daniel Van Dam (West Coxsackie, New York); James Pellegrino Alexander (Ballston Lake, New York); Murtuza Yusuf Lokhandwalla (Canton, Michigan) |
| ABSTRACT | In one embodiment, an apparatus includes a rotor shaft, at least one pole segment, at least one pole tip segment and at least one permanent magnet pair. The at least one pole segment is mechanically coupled to the rotor shaft. Each permanent magnet pair is disposed between the at least one pole segment and respective pole tip segment. The apparatus further includes at least one mechanical member that mechanically restrains the at least one pole tip segment to at least one of the rotor shaft or the at least one pole segment. |
| FILED | Friday, July 29, 2011 |
| APPL NO | 13/194047 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/156.530 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618976 | Paglieroni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David W. Paglieroni (Pleasanton, California); Jeffrey E. Mast (Loveland, Colorado); N. Reginald Beer (Pleasanton, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | David W. Paglieroni (Pleasanton, California); Jeffrey E. Mast (Loveland, Colorado); N. Reginald Beer (Pleasanton, California) |
| ABSTRACT | A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object. |
| FILED | Friday, August 26, 2011 |
| APPL NO | 13/219482 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620410 | Frangioni |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John V. Frangioni (Wayland, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | John V. Frangioni (Wayland, Massachusetts) |
| ABSTRACT | A medical imaging system provides simultaneous rendering of visible light and fluorescent images. The system may employ dyes in a small-molecule form that remain in a subject's blood stream for several minutes, allowing real-time imaging of the subject's circulatory system superimposed upon a conventional, visible light image of the subject. The system may provide an excitation light source to excite the fluorescent substance and a visible light source for general illumination within the same optical guide used to capture images. The system may be configured for use in open surgical procedures by providing an operating area that is closed to ambient light. The systems described herein provide two or more diagnostic imaging channels for capture of multiple, concurrent diagnostic images and may be used where a visible light image may be usefully supplemented by two or more images that are independently marked for functional interest. |
| FILED | Tuesday, July 03, 2007 |
| APPL NO | 12/307204 |
| ART UNIT | 3777 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery 6/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620614 | Battiste |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard L. Battiste (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Richard L. Battiste (Oak Ridge, Tennessee) |
| ABSTRACT | Methods and apparatus are described for characterizing the temporal-spatial properties of a dynamic fluid front within a mold space while the mold space is being filled with fluid. A method includes providing a mold defining a mold space and having one or more openings into the mold space; heating a plurality of temperature sensors that extend into the mold space; injecting a fluid into the mold space through the openings, the fluid experiencing a dynamic fluid front while filling the mold space with the fluid; and characterizing temporal-spatial properties of the dynamic fluid front by monitoring a temperature of each of the plurality of heated temperature sensors while the mold space is being filled with the fluid. An apparatus includes a mold defining a mold space; one or more openings for introducing a fluid into the mold space and filling the mold space with the fluid, the fluid experiencing a dynamic fluid front while filling the mold space; a plurality of heated temperature sensors extending into the mold space; and a computer coupled to the plurality of heated temperature sensors for characterizing the temporal-spatial properties of the dynamic fluid front. |
| FILED | Friday, November 30, 2007 |
| APPL NO | 11/998597 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08621167 | Gara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan Gara (Mount Kisco, New York); Valentina Salapura (Chappaqua, New York); Robert W. Wisniewski (Ossining, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alan Gara (Mount Kisco, New York); Valentina Salapura (Chappaqua, New York); Robert W. Wisniewski (Ossining, New York) |
| ABSTRACT | A device for copying performance counter data includes hardware path that connects a direct memory access (DMA) unit to a plurality of hardware performance counters and a memory device. Software prepares an injection packet for the DMA unit to perform copying, while the software can perform other tasks. In one aspect, the software that prepares the injection packet runs on a processing core other than the core that gathers the hardware performance counter data. |
| FILED | Friday, April 13, 2012 |
| APPL NO | 13/446467 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/162 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08621446 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ABSTRACT | Compiling software for a hierarchical distributed processing system including providing to one or more compiling nodes software to be compiled, wherein at least a portion of the software to be compiled is to be executed by one or more other nodes; compiling, by the compiling node, the software; maintaining, by the compiling node, any compiled software to be executed on the compiling node; selecting, by the compiling node, one or more nodes in a next tier of the hierarchy of the distributed processing system in dependence upon whether any compiled software is for the selected node or the selected node's descendants; sending to the selected node only the compiled software to be executed by the selected node or selected node's descendant. |
| FILED | Thursday, April 29, 2010 |
| APPL NO | 12/770353 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/149 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08621478 | Ahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Ahn (Yorktown Heights, New York); Luis H. Ceze (Urbana, Illinois); Dong Chen (Croton On Hudson, New York); Alan Gara (Mount Kisco, New York); Philip Heidelberger (Cortlandt Manor, New York); Martin Ohmacht (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Daniel Ahn (Yorktown Heights, New York); Luis H. Ceze (Urbana, Illinois); Dong Chen (Croton On Hudson, New York); Alan Gara (Mount Kisco, New York); Philip Heidelberger (Cortlandt Manor, New York); Martin Ohmacht (Yorktown Heights, New York) |
| ABSTRACT | A multiprocessor system supports multiple concurrent modes of speculative execution. Speculation identification numbers (IDs) are allocated to speculative threads from a pool of available numbers. The pool is divided into domains, with each domain being assigned to a mode of speculation. Modes of speculation include TM, TLS, and rollback. Allocation of the IDs is carried out with respect to a central state table and using hardware pointers. The IDs are used for writing different versions of speculative results in different ways of a set in a cache memory. |
| FILED | Tuesday, January 18, 2011 |
| APPL NO | 13/008502 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/104 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08615812 | Wójtowicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marek A. Wójtowicz (East Hartford, Connecticut); Eric P. Rubenstein (Longmeadow, Massachusetts); Michael A. Serio (Sturbridge, Massachusetts); Joseph E. Cosgrove (Columbia, Connecticut) |
| ASSIGNEE(S) | Advanced Fuel Research, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Marek A. Wójtowicz (East Hartford, Connecticut); Eric P. Rubenstein (Longmeadow, Massachusetts); Michael A. Serio (Sturbridge, Massachusetts); Joseph E. Cosgrove (Columbia, Connecticut) |
| ABSTRACT | High-strength porous carbon and a method of its manufacture are described for multifunctional applications, such as ballistic protection, structural components, ultracapacitor electrodes, gas storage, and radiation shielding. The carbon is produced from a polymer precursor via carbonization, and optionally by surface activation and post-treatment. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 12/798218 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparel 02/2.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616328 | Daraio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institue of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Chiara Daraio (Pasadena, California); Fernando Fraternali (Avellino, Italy) |
| ABSTRACT | A tensegrity apparatus having multiple tensegrity units for the transmission of solitary waves with adjustable profiles into a material or structure, and the detection of such waves from a material or structure. |
| FILED | Thursday, February 21, 2013 |
| APPL NO | 13/772904 |
| ART UNIT | 2832 — Fluid Handling and Dispensing |
| CURRENT CPC | Acoustics 181/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08616712 | Rolland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jannick P. Rolland (Pittsford, New York); Kyle Fuerschbach (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Jannick P. Rolland (Pittsford, New York); Kyle Fuerschbach (Rochester, New York) |
| ABSTRACT | A new family of truly nonsymmetric optical systems that exploit a new fabrication degree of freedom enabled by the introduction of slow-servos to diamond machining; surfaces whose departure from a sphere varies both radially and azimuthally in the aperture, and associated design method. |
| FILED | Monday, March 26, 2012 |
| APPL NO | 13/429771 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/858 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617522 | Sharma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Parvesh Sharma (Gainesville, Florida); Brij M. Moudgil (Gainesville, Florida); Glenn A. Walter (Newberry, Florida); Stephen R. Grobmyer (Shaker Heights, Ohio); Swadeshmukul Santra (Orlando, Florida); Huabei Jiang (Gainesville, Florida); Scott Chang Brown (Hockessin, Delaware); Edward W. Scott (Gainesville, Florida); Qizhi Zhang (Gainesville, Florida); Niclas Bengtsson (Lake Forest Park, Washington) |
| ABSTRACT | Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging. |
| FILED | Friday, December 28, 2012 |
| APPL NO | 13/729815 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617592 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shaoyi Jiang (Redmond, Washington); Zhiqiang Cao (Somerville, Massachusetts); Hong Xue (Pleasanton, California); Lei Zhang (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Shaoyi Jiang (Redmond, Washington); Zhiqiang Cao (Somerville, Massachusetts); Hong Xue (Pleasanton, California); Lei Zhang (Seattle, Washington) |
| ABSTRACT | Zwitterionic block copolymers and zwitterionic conjugates that advantageously self-assemble into particles, particles assembled from the zwitterionic block copolymers and zwitterionic conjugates, pharmaceutical compositions that include the self-assembled particles, and methods for delivering therapeutic and diagnostic agents using the particles. |
| FILED | Thursday, May 03, 2012 |
| APPL NO | 13/463662 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617707 | Krauss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Todd D. Krauss (Penfield, New York); Christopher Evans (Rochester, New York); Li Guo (Rockville, Maryland); Jeffrey J. Peterson (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Todd D. Krauss (Penfield, New York); Christopher Evans (Rochester, New York); Li Guo (Rockville, Maryland); Jeffrey J. Peterson (Rochester, New York) |
| ABSTRACT | Disclosed herein are magic size nanoclusters comprising lead and one or more chalcogens. The disclosed magic size nanoclusters have both spectrally narrow fluorescence and ultra-high quantum efficiencies. Further disclosed herein is a method for preparing PbS, PbSe, and PbTe magic size nanoclusters. The yield of magic size nanoclusters can be increased by using anion sources enriched for secondary phosphines. The use of enriched secondary phosphine anion sources also increases the yield of quantum nanostructures. |
| FILED | Tuesday, March 24, 2009 |
| APPL NO | 12/988992 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/402 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617798 | Mason et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas G. Mason (Los Angeles, California); Carlos J. Hernandez (San Leandro, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Thomas G. Mason (Los Angeles, California); Carlos J. Hernandez (San Leandro, California) |
| ABSTRACT | A method of producing particles includes providing a substrate structure that comprises a solid substrate; forming a target structure on said substrate structure, said target structure comprising a radiation-reactive material; forming a spatially patterned beam of radiation using a patterned mask; exposing at least a portion of the target structure to the spatially patterned beam of radiation to which the radiation-reactive material reacts while leaving other portions of the target structure unexposed to the radiation; removing substantially all of one of the exposed or the unexposed patterned portions of the target structure to provide a plurality of non-contiguous structures that include at least a portion of the radiation-reactive material; and separating the plurality of non-contiguous structures comprising the radiation-reactive material from the substrate structure into a fluid material. Each non-contiguous structure of the radiation-reactive material provides at least a portion of a separate particle after the separation. |
| FILED | Friday, August 17, 2007 |
| APPL NO | 12/377773 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617814 | Bazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (San Diego, California); Shu Wang (Beijing, China PRC) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (San Diego, California); Shu Wang (Beijing, China PRC) |
| ABSTRACT | Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor polynucleotide complementary to the target polynucleotide. The sensor polynucleotide comprises a signaling chromophore to receive energy from the excited multichromophore and increase emission in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided. |
| FILED | Monday, July 09, 2012 |
| APPL NO | 13/544303 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617885 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chengcheng Zhang (Arlington, Massachusetts); Harvey Lodish (Brookline, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Chengcheng Zhang (Arlington, Massachusetts); Harvey Lodish (Brookline, Massachusetts) |
| ABSTRACT | Hematopoietic stem cells and methods for ex vivo expansion of hematopoietic stem cells are provided. The methods comprise culturing the cells in a media containing an effective amount insulin-like growth factor(IGF), fibroblast growth factor (FGF), thrombopoietin (TPO), and stem cell factor (SCF), under conditions sufficient for expansion of said cells. Methods for identifying expanded hematopoeitc stem cells and kits for ex vivo expansion of hematopoietic stem cells are also provided. |
| FILED | Tuesday, July 06, 2010 |
| APPL NO | 12/830709 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618327 | Blackwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Helen E. Blackwell (Middleton, Wisconsin); Matthew D. Bowman (Vernon, Connecticut); Jennifer C. O'Neill (Madison, Wisconsin); Joseph R. Stringer (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Helen E. Blackwell (Middleton, Wisconsin); Matthew D. Bowman (Vernon, Connecticut); Jennifer C. O'Neill (Madison, Wisconsin); Joseph R. Stringer (Madison, Wisconsin) |
| ABSTRACT | The present invention relates generally to compounds providing antibacterial therapeutic agents and preparations, and related methods of using and making antibacterial compounds. Antibacterial compounds of the present invention include chalcone, alkylpyrimidine, aminopyrimidine and cyanopyridine compounds and derivatives thereof exhibiting minimum inhibitory concentrations (MIC) similar to or less than conventional antibacterial compounds in wide use. For example, the present invention provides chalcone and cyanopyridine compounds, and derivatives thereof, exhibiting high antibacterial activities having multiple electron withdrawing group substituents, such as halogens and fluorinated alkyl groups, and optionally having hydroxyl and/or alkoxyl groups substituents. |
| FILED | Friday, July 06, 2012 |
| APPL NO | 13/543572 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/442 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618470 | Dantus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marcos Dantus (Okemos, Michigan); Vadim V. Lozovoy (Holt, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Marcos Dantus (Okemos, Michigan); Vadim V. Lozovoy (Holt, Michigan) |
| ABSTRACT | Enantiomers are characterized, identified, synthesized and/or modified with a shaped laser pulse. In another aspect of the present invention, binary shaping and circular polarization are employed with a laser pulse. A further aspect of the present invention provides a quarter-wave plate in combination with one or more pulse shapers. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 12/085878 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618475 | Clemmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David E. Clemmer (Bloomington, Indiana); Stormy L. Koeniger (Evanston, Illinois); Stephen J. Valentine (Bloomington, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | David E. Clemmer (Bloomington, Indiana); Stormy L. Koeniger (Evanston, Illinois); Stephen J. Valentine (Bloomington, Indiana) |
| ABSTRACT | An ion mobility spectrometer comprises a drift tube defining a drift tube inlet configured to receive ions and a drift tube outlet. The drift tube is configured to separate ions in time as a function of ion mobility. The drift tube defines a first ion activation region between the drift tube inlet and the drift tube outlet. The first ion activation region is configured to selectively induce structural changes in at least some of the ions. |
| FILED | Wednesday, March 02, 2011 |
| APPL NO | 13/038544 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618595 | Korgel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian A. Korgel (Round Rock, Texas); Keith P. Johnston (Austin, Texas); Katherine Brosh (Austin, Texas); Paul Thurk (Austin, Texas) |
| ASSIGNEE(S) | Merck Patent GmbH (Frankfurter, Germany) |
| INVENTOR(S) | Brian A. Korgel (Round Rock, Texas); Keith P. Johnston (Austin, Texas); Katherine Brosh (Austin, Texas); Paul Thurk (Austin, Texas) |
| ABSTRACT | A method for the production of a robust, chemically stable, crystalline, passivated nanoparticle and composition containing the same, that emit light with high efficiencies and size-tunable and excitation energy tunable color. The methods include the thermal degradation of a precursor molecule in the presence of a capping agent at high temperature and elevated pressure. A particular composition prepared by the methods is a passivated silicon nanoparticle composition displaying discrete optical transitions. |
| FILED | Thursday, May 05, 2005 |
| APPL NO | 11/122223 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Active solid-state devices 257/315 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618612 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chongwu Zhou (Arcadia, California); Koungmin Ryu (Los Angeles, California); Alexander Badmaev (Pasadena, California); Chuan Wang (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Chongwu Zhou (Arcadia, California); Koungmin Ryu (Los Angeles, California); Alexander Badmaev (Pasadena, California); Chuan Wang (Los Angeles, California) |
| ABSTRACT | Techniques, apparatus and systems are described for wafer-scale processing of aligned nanotube devices and integrated circuits. In one aspect, a method can include growing aligned nanotubes on at least one of a wafer-scale quartz substrate or a wafer-scale sapphire substrate. The method can include transferring the grown aligned nanotubes onto a target substrate. Also, the method can include fabricating at least one device based on the transferred nanotubes. |
| FILED | Friday, April 13, 2012 |
| APPL NO | 13/447105 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/369 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618914 | Bachman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark Bachman (Irvine, California); Yang Zhang (Irvine, California); Scott McLaughlin (Irvine, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mark Bachman (Irvine, California); Yang Zhang (Irvine, California); Scott McLaughlin (Irvine, California) |
| ABSTRACT | An apparatus provides environmental monitoring of an item and includes an RFID tag, and a passive switch for sensing an environmental parameter to which the item is subjected, and coupled to the RFID tag so that a measurement of the sensed environmental parameter can be stored, the RFID tag for providing remote readout of the sensed environmental parameter. A method provides environmental monitoring of an item and includes the steps of sensing an environmental parameter to which the item is subjected with activation of a passive switch, storing a measurement of the sensed environmental parameter upon the event of activation of the passive switch, and providing remote readout of the measurement of the sensed environmental parameter with an RFID tag. |
| FILED | Tuesday, January 04, 2011 |
| APPL NO | 12/984451 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Communications: Electrical 340/10.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619832 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Qing Hu (Wellesley, Massachusetts); Alan Wei Min Lee (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Qing Hu (Wellesley, Massachusetts); Alan Wei Min Lee (Boston, Massachusetts) |
| ABSTRACT | Terahertz quantum cascade (QC) devices are disclosed that can operate, e.g., in a range of about 1 THz to about 10 THz. In some embodiments, QC lasers are disclosed in which an optical element (e.g., a lens) is coupled to an output facet of the laser's active region to enhance coupling of the lasing radiation from the active region to an external environment. In other embodiments, terahertz amplifier and tunable terahertz QC lasers are disclosed. |
| FILED | Friday, May 08, 2009 |
| APPL NO | 12/437818 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/50.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620065 | Piestun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rafael Piestun (Boulder, Colorado); Sean Albert Quirin (Longmont, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Rafael Piestun (Boulder, Colorado); Sean Albert Quirin (Longmont, Colorado) |
| ABSTRACT | Embodiments include methods, systems, and/or devices that may be used to image, obtain three-dimensional information from a scence, and/or locate multiple small particles and/or objects in three dimensions. A point spread function (PSF) with a predefined three dimensional shape may be implemented to obtain high Fisher information in 3D. The PSF may be generated via a phase mask, an amplitude mask, a hologram, or a diffractive optical element. The small particles may be imaged using the 3D PSF. The images may be used to find the precise location of the object using an estimation algorithm such as maximum likelihood estimation (MLE), expectation maximization, or Bayesian methods, for example. Calibration measurements can be used to improve the theoretical model of the optical system. Fiduciary particles/targets can also be used to compensate for drift and other type of movement of the sample relative to the detector. |
| FILED | Monday, April 11, 2011 |
| APPL NO | 13/084345 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/154 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620254 | Molnar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alyosha Molnar (Ithaca, New York); Caroline Andrews (San Francisco, California) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Alyosha Molnar (Ithaca, New York); Caroline Andrews (San Francisco, California) |
| ABSTRACT | The present invention is directed to a wireless communications device that includes an antenna configured to receive an RF signal from an ambient environment. The antenna is characterized by an antenna impedance and the RF signal is characterized by a predetermined frequency. A passive mixer assembly is coupled to the antenna without an RF matching network. The passive mixer assembly is characterized by a passive mixer impedance presented to the antenna. The passive mixer assembly includes a plurality of baseband mixer ports. The passive mixer assembly is configured to downconvert the RF signal and provide a plurality of baseband signals. Each baseband signal of the plurality of baseband signals is directed out of a corresponding port of the plurality of baseband mixer ports and characterized by a predetermined phase of a plurality of predetermined phases. A baseband low noise amplifier (baseband-LNA) assembly is coupled to the passive mixer assembly. The baseband-LNA assembly includes a baseband-LNA input portion configured to receive the plurality of baseband signals from the passive mixer assembly. The baseband-LNA assembly is configured to provide a plurality of amplified baseband signals from a baseband-LNA output portion. A baseband feedback network is coupled between the baseband-LNA output portion and the baseband-LNA input portion. The baseband feedback network includes a plurality of first adjustable resistive components. The plurality of first adjustable resistive components is selectively adjustable such that the passive mixer impedance is substantially matched to the antenna impedance at the predetermined RF frequency. |
| FILED | Thursday, February 03, 2011 |
| APPL NO | 13/576528 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08620591 | Wegerich |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephan W. Wegerich (Geneva, Illinois) |
| ASSIGNEE(S) | Venture Gain LLC (Naperville, Illinois) |
| INVENTOR(S) | Stephan W. Wegerich (Geneva, Illinois) |
| ABSTRACT | Ambulatory or in-hospital monitoring of patients is provided with early warning and prioritization, enabling proactive intervention and amelioration of both costs and risks of health care. Multivariate physiological parameters are estimated by empirical model to remove normal variation. Residuals are tested using a multivariate probability density function to provide a multivariate health index for prioritizing medical effort. |
| FILED | Tuesday, January 04, 2011 |
| APPL NO | 12/984400 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08615812 | Wójtowicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marek A. Wójtowicz (East Hartford, Connecticut); Eric P. Rubenstein (Longmeadow, Massachusetts); Michael A. Serio (Sturbridge, Massachusetts); Joseph E. Cosgrove (Columbia, Connecticut) |
| ASSIGNEE(S) | Advanced Fuel Research, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Marek A. Wójtowicz (East Hartford, Connecticut); Eric P. Rubenstein (Longmeadow, Massachusetts); Michael A. Serio (Sturbridge, Massachusetts); Joseph E. Cosgrove (Columbia, Connecticut) |
| ABSTRACT | High-strength porous carbon and a method of its manufacture are described for multifunctional applications, such as ballistic protection, structural components, ultracapacitor electrodes, gas storage, and radiation shielding. The carbon is produced from a polymer precursor via carbonization, and optionally by surface activation and post-treatment. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 12/798218 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparel 02/2.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617819 | Swager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy M. Swager (Newton, Massachusetts); Peter H. Seeberger (Zurich, Switzerland); Juan Zheng (Cambridge, Massachusetts); Matthew D. Disney (Williamsville, New York) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Peter H. Seeberger (Zurich, Switzerland); Juan Zheng (Cambridge, Massachusetts); Matthew D. Disney (Williamsville, New York) |
| ABSTRACT | The present invention generally relates to organic polymers able to participate in an analyte-recognition process, where an analyte facilitates an energy transfer between an energy donor and an energy acceptor. Certain embodiments of the invention make use of fluorescent conjugated polymers, such as poly(phenylene ethynylene)s and other polymers comprising pi-conjugated backbones. For example, one aspect of the invention provides a fluorescent conjugated polymer and an indicator that can interact with each other in the presence of an analyte to produce an emissive signal. In some cases, the interaction may include energy exchange mechanisms, such as Dexter energy transfer or the strong coupling effect. The interaction of the conjugated polymer and the indicator, in some instances, may be facilitated through specific interactions, such as a protein/carbohydrate interaction, a ligand/receptor interaction, etc. Another aspect of the invention provides for the detection of biological entities, for example, pathogenic bacteria such as E. coli, or viruses such as influenza virus. In some cases, biological recognition elements may be used to determine the biological entity, for instance, carbohydrates that can be used to specifically interact with at least part of the biological entity, such as a protein in the cell membrane of a bacterium. Still other aspects of the invention involve articles, devices, and kits using any of the above-described systems. |
| FILED | Monday, September 19, 2005 |
| APPL NO | 11/230308 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618762 | Reiland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew J. Reiland (Oxford, Michigan); Myron A. Diftler (Houston, Texas) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan); The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Matthew J. Reiland (Oxford, Michigan); Myron A. Diftler (Houston, Texas) |
| ABSTRACT | A tendon tensioning system includes a tendon having a proximal end and a distal end, an actuator, and a motor controller. The actuator may include a drive screw and a motor, and may be coupled with the proximal end of the tendon and configured to apply a tension through the tendon in response to an electrical current. The motor controller may be electrically coupled with the actuator, and configured to provide an electrical current having a first amplitude to the actuator until a stall tension is achieved through the tendon; provide a pulse current to the actuator following the achievement of the stall tension, where the amplitude of the pulse current is greater than the first amplitude, and return the motor to a steady state holding current following the conclusion of the pulse current. |
| FILED | Thursday, January 27, 2011 |
| APPL NO | 13/014901 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Motive power systems 318/568.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618933 | Jensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott L. Jensen (Carrier, Mississippi); George J. Drouant (Mandeville, Louisiana) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Scott L. Jensen (Carrier, Mississippi); George J. Drouant (Mandeville, Louisiana) |
| ABSTRACT | A monitoring system is disclosed, which includes a base station and at least one sensor unit that is separate from the base station. The at least one sensor unit resides in a dormant state until it is awakened by the triggering of a vibration-sensitive switch. Once awakened, the sensor may take a measurement, and then transmit to the base station the measurement. Once data is transmitted from the sensor to the base station, the sensor may return to its dormant state. There may be various sensors for each base station and the various sensors may optionally measure different quantities, such as current, voltage, single-axis and/or three-axis magnetic fields. |
| FILED | Tuesday, October 02, 2007 |
| APPL NO | 11/866042 |
| ART UNIT | 2682 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Communications: Electrical 340/539.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619832 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Qing Hu (Wellesley, Massachusetts); Alan Wei Min Lee (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Qing Hu (Wellesley, Massachusetts); Alan Wei Min Lee (Boston, Massachusetts) |
| ABSTRACT | Terahertz quantum cascade (QC) devices are disclosed that can operate, e.g., in a range of about 1 THz to about 10 THz. In some embodiments, QC lasers are disclosed in which an optical element (e.g., a lens) is coupled to an output facet of the laser's active region to enhance coupling of the lasing radiation from the active region to an external environment. In other embodiments, terahertz amplifier and tunable terahertz QC lasers are disclosed. |
| FILED | Friday, May 08, 2009 |
| APPL NO | 12/437818 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/50.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08617395 | Offeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard D Offeman (Pinole, California); Charles N Ludvik (Moraga, California) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Richard D Offeman (Pinole, California); Charles N Ludvik (Moraga, California) |
| ABSTRACT | The present invention is a technique to fabricate thin-film composite perm-selective membranes by a transfer method. The composite membranes are useful in separating liquid, vapor or gaseous mixtures by selective permeation and reduce mass transfer resistance of the support layer. Selectivity and flux are improved by reduction of the mass transfer resistance of the support layer. |
| FILED | Monday, November 08, 2010 |
| APPL NO | 12/941776 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/640 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617812 | Richt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Juergen A. Richt (Manhattan, Kansas) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Juergen A. Richt (Manhattan, Kansas) |
| ABSTRACT | A specific, non-synonymous SNP in the Prnp gene encoding the bovine prion protein affects the susceptibility of bovine animals to bovine spongiform encephalopathy (BSE). Depending on the number of octapeptide repeat units present in the Prnp gene, the position of the SNP is either nucleotide 631 of exon 3 (codon 211) when the Prnp gene comprises six octapeptide repeat region sequences, nucleotide 607 of exon 3 (codon 203) when the Prnp gene comprises five octapeptide repeat region sequences, or nucleotide 655 of exon 3 (codon 219) when the Prnp gene comprises seven octapeptide repeat region sequences. Alleles of the bovine Prnp wherein the SNP at these positions is lysine (K) at the corresponding amino acids (i.e., 211, 203 or 219) in the bovine prion protein are all indicative of increased susceptibility to BSE in comparison to alleles which encode glutamic acid (E) at the same position. This SNP may be used as a marker for selecting bovines susceptible to BSE for disposal and/or removal from breeding, the human food and animal feed supplies. |
| FILED | Thursday, December 16, 2010 |
| APPL NO | 12/969744 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618271 | Obendorf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ralph L. Obendorf (Ithaca, New York); Ueda Takashi (Fort Myers, Florida) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Ralph L. Obendorf (Ithaca, New York); Ueda Takashi (Fort Myers, Florida) |
| ABSTRACT | The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described. The method includes providing a fagopyritol synthase, providing a substrate comprising a galactosyl donor and a galactosyl acceptor, and combining the fagopyritol synthase with the substrate under conditions effective produce a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor. |
| FILED | Friday, May 21, 2010 |
| APPL NO | 12/785097 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618353 | Kindiger |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Bryan K. Kindiger (El Reno, Oklahoma) |
| ABSTRACT | Dihaploid homozygous Fescue species may be produced by interspecific hybridization of Fescue with novel ryegrass, Lolium multiflorus, lines, that induce genome loss. Plants that are dihaploid homozygous Lolium and amphidiploids are also produced. |
| FILED | Monday, December 03, 2012 |
| APPL NO | 13/692074 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/269 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08617608 | Zale et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BIND Therapeutics, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | BIND Therapeutics, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Stephen E. Zale (Hopkinton, Massachusetts); Greg Troiano (Pembroke, Massachusetts); Mir Mukkaram Ali (Woburn, Massachusetts); Jeff Hrkach (Lexington, Massachusetts); James Wright (Lexington, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles. |
| FILED | Tuesday, May 28, 2013 |
| APPL NO | 13/903549 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/337 (20130101) Acyclic or Carbocyclic Compounds C07C 59/08 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08617997 | Chitnis |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ashay Chitnis (Goleta, California) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Ashay Chitnis (Goleta, California) |
| ABSTRACT | The present invention is directed to post-deposition, wet etch processes for patterning AuSn solder material and devices fabricated using such processes. The processes can be applied to uniform AuSn layers to generate submicron patterning of thin AuSn layers having a wide variety of features. The use of multiple etching steps that alternate between different mixes of chemicals enables the etch to proceed effectively, and the same or similar processes can be used to etch under bump metallization. The processes are simple, cost-effective, do not contaminate equipment or tools, and are compatible with standard cleanroom fabrication processes. |
| FILED | Tuesday, August 21, 2007 |
| APPL NO | 11/894917 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/714 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08618510 | Palmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amy E. Palmer (Boulder, Colorado); Ralph Jimenez (Boulder, Colorado); Kevin Dean (Lafayette, Colorado); Jennifer Lubbeck (Boulder, Colorado); Lloyd M. Davis (Tullahoma, Tennessee) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado); University of Tennessee Research Foundation (Knoxville, Tennessee); National Institute of Standards and Technology (Gaithersburg, Maryland) |
| INVENTOR(S) | Amy E. Palmer (Boulder, Colorado); Ralph Jimenez (Boulder, Colorado); Kevin Dean (Lafayette, Colorado); Jennifer Lubbeck (Boulder, Colorado); Lloyd M. Davis (Tullahoma, Tennessee) |
| ABSTRACT | Devices and methods for screening emissive properties of a cell, such as the resistance to photobleaching or other photophysical property. In one example, a device may include a microfluidic reservoir having at least an input channel for receiving the cell, a main channel fluidly coupled with the input channel, at least a first output channel and a second output channel, the first and second output channels fluidly coupled with the main channel; and a multibeam interrogation section generating a plurality of light beams impinging upon the main channel of the microfluidic reservoir. As a cell passes from the input channel through the main channel of the microfluidic reservoir, the cell is exposed to the plurality of light beams thereby generating emissions that are received by a signal processing section. A cell trapping section selectively diverts the cell to the second output channel if the cell contains desired emissive properties. |
| FILED | Saturday, January 28, 2012 |
| APPL NO | 13/360706 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/461.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 08618162 | Carlier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Carlier (Blacksburg, Virginia); Jeffrey Bloomquist (Blacksburg, Virginia); Sally Paulson (Blacksburg, Virginia); Eric Wong (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Paul Carlier (Blacksburg, Virginia); Jeffrey Bloomquist (Blacksburg, Virginia); Sally Paulson (Blacksburg, Virginia); Eric Wong (Blacksburg, Virginia) |
| ABSTRACT | The present invention includes insecticidal carbamates that are useful, for example, for the control of insects, such as mosquitoes, which can be used in applications where exposure to and/or contact with humans is likely. The insecticides of the present invention include phenyl N-methyl carbamates and compositions comprising them that exhibit species-selective inhibition of acetylcholinesterase (AChE) and are preferably toxic to mosquitoes but not humans. Of particular interest are compounds of Formula (I) and Formula (II): Compounds of Formula (I) and Formula (II) are especially suitable for insecticide treated nets and indoor residual spraying for mosquito control. |
| FILED | Thursday, January 26, 2012 |
| APPL NO | 13/358586 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619237 | Hillman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Matthew B. Bouchard (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth Marjorie Clare Hillman (New York, New York); Matthew B. Bouchard (New York, New York) |
| ABSTRACT | Laser-Scanning Intersecting Plane Tomography (L-SIPT) can provide a non-contact imaging geometry that can allow high speed volumetric scanning, such as of non-scattering to moderately scattering tissues. The L-SIPT imaging apparatus can include a first lens, located and configured to receive from a sample light received from different depths of the sample. A first light redirector can be located and configured to receive via the first lens and to redirect light received from the different depths of the sample to provide redirected light to a light detector capable of detecting individual measurements of light at different locations along a first direction. A second light redirector can be located and configured to redirect light received from a light source to provide redirected light to the sample, wherein the second light redirector is in a specified spatial relationship to the first light redirector, and wherein the first and second light redirectors are configured to be adjusted during a scan of the sample so as to provide the specified spatial relationship during the scan. |
| FILED | Monday, December 06, 2010 |
| APPL NO | 12/961074 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08617549 | Sierks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Sierks (Ft. McDowell, Arizona); Shanta Boddapati (Tempe, Arizona); Srinath Kasturirangan (Germantown, Maryland) |
| ASSIGNEE(S) | Arizona Board of Regents, A Body Corporate of the State of Arizona, Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Michael Sierks (Ft. McDowell, Arizona); Shanta Boddapati (Tempe, Arizona); Srinath Kasturirangan (Germantown, Maryland) |
| ABSTRACT | The present invention provides for the treatment of Alzheimer's disease. More specifically, a recombinant bispecific antibody fragment that simultaneously blocks beta-secretase activity while also promoting alpha-secretase activity, comprising a first portion and a second portion, wherein the first portion blocks beta secretase activity and the second portion promotes alpha-secretase activity. |
| FILED | Wednesday, September 08, 2010 |
| APPL NO | 13/395011 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/136.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08619447 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bingsen Wang (Okemos, Michigan); Craig R. Bush (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Bingsen Wang (Okemos, Michigan); Craig R. Bush (Tempe, Arizona) |
| ABSTRACT | Some embodiments include an apparatus. The apparatus includes a DC source port having a first DC source terminal and a second DC source terminal. Further, the apparatus includes a first switch, a second switch, and a third switch having first terminals coupled together, and the apparatus includes a fourth switch between the first switch and the second DC source terminal, a fifth switch between the second switch and the second DC source terminal, and a sixth switch between the third switch and the second DC source terminal. Also, the apparatus includes a first inductor coupled between the first DC source terminal and the first terminals of the first, second, and third switches, and a power grid port having a first power grid terminal and a second power grid terminal. Other related systems and methods are also disclosed. |
| FILED | Wednesday, March 30, 2011 |
| APPL NO | 13/075579 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electric power conversion systems 363/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 08621610 | Oberheide et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jon Oberheide (Troy, Michigan); Evan Cooke (Cambridge, Massachusetts); Farnam Jahanian (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Jon Oberheide (Troy, Michigan); Evan Cooke (Cambridge, Massachusetts); Farnam Jahanian (Ann Arbor, Michigan) |
| ABSTRACT | A system is provided for detecting, analyzing and quarantining unwanted files in a network environment. A host agent residing on a computing device in the network environment detects a new file introduced to the computing device and sends the new file to a network service for analysis. The network service is accessible to computing devices in the network environment. An architecture for the network service may include: a request dispatcher configured to receive a candidate file for inspection from a given computing device in the network environment and distribute the candidate file to one or more of a plurality of detection engines, where the detection engines operate in parallel to analyze the candidate file and output a report regarding the candidate file; and a result aggregator configured to receive reports from each of the detection engines regarding the candidate file and aggregates the reports in accordance with an aggregation algorithm. |
| FILED | Tuesday, August 05, 2008 |
| APPL NO | 12/186014 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Information security 726/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 08620089 | Korah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thommen Korah (Marina Del Rey, California); Swarup S. Medasani (Thousand Oaks, California); Yuri Owechko (Newbury Park, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Thommen Korah (Marina Del Rey, California); Swarup S. Medasani (Thousand Oaks, California); Yuri Owechko (Newbury Park, California) |
| ABSTRACT | A method of recognizing features in a 3D environment includes using a sensor that collects a plurality of sensed data points, populating a strip histogram grid having a plurality of strips, each strip having a dx dimension and a dy dimension, by assigning each sensed data point to a strip in the strip histogram grid that has x, y and z dimensions that encompass the spatial coordinate information of the respective assigned sensed data point, and estimating the local ground plane for a strip in the strip histogram grid by using information on each sensed data point assigned to that strip and surrounding strips in the strip histogram grid. Further methods include extracting smooth surfaces, building segmentation, top down segmentation and bottom up segmentation. |
| FILED | Tuesday, December 22, 2009 |
| APPL NO | 12/644349 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/195 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 08618241 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baoquan Chen (Bothell, Washington); Danliang Jin (Bothell, Washington); Guomin Yu (Bothell, Washington); Hui Chen (Kirkland, Washington); Diyun Huang (Watertown, Massachusetts) |
| ASSIGNEE(S) | GigOptix, Inc. (San Jose, California) |
| INVENTOR(S) | Baoquan Chen (Bothell, Washington); Danliang Jin (Bothell, Washington); Guomin Yu (Bothell, Washington); Hui Chen (Kirkland, Washington); Diyun Huang (Watertown, Massachusetts) |
| ABSTRACT | According to an embodiment, an electro-optic polymer comprises a host polymer and a guest nonlinear optical chromophore having the structure D-π-A, wherein: D is a donor, π is a π-bridge, and A is an acceptor; a bulky substituent group is covalently attached to at least one of D, π, or A; and the bulky substituent group has at least one non-covalent interaction with part of the host polymer that impedes chromophore depoling. |
| FILED | Friday, December 03, 2010 |
| APPL NO | 12/959898 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08620961 | Ittycheriah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Abraham Ittycheriah (Brookfield, Connecticut); Hongyan Jing (White Plains, New York); Nandakishore Kambhatla (White Plains, New York); Xiaoqiang Luo (Ardsley, New York); Salim E. Roukos (Scarsdale, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Abraham Ittycheriah (Brookfield, Connecticut); Hongyan Jing (White Plains, New York); Nandakishore Kambhatla (White Plains, New York); Xiaoqiang Luo (Ardsley, New York); Salim E. Roukos (Scarsdale, New York) |
| ABSTRACT | A Bell Tree data structure is provided to model the process of chaining the mentions, from one or more documents, into entities, tracking the entire process; where the data structure is used in an entity tracking process that produces multiple results ranked by a product of probability scores. |
| FILED | Monday, May 05, 2008 |
| APPL NO | 12/115321 |
| ART UNIT | 2155 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Database and file management or data structures 77/797 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08618914 | Bachman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark Bachman (Irvine, California); Yang Zhang (Irvine, California); Scott McLaughlin (Irvine, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mark Bachman (Irvine, California); Yang Zhang (Irvine, California); Scott McLaughlin (Irvine, California) |
| ABSTRACT | An apparatus provides environmental monitoring of an item and includes an RFID tag, and a passive switch for sensing an environmental parameter to which the item is subjected, and coupled to the RFID tag so that a measurement of the sensed environmental parameter can be stored, the RFID tag for providing remote readout of the sensed environmental parameter. A method provides environmental monitoring of an item and includes the steps of sensing an environmental parameter to which the item is subjected with activation of a passive switch, storing a measurement of the sensed environmental parameter upon the event of activation of the passive switch, and providing remote readout of the measurement of the sensed environmental parameter with an RFID tag. |
| FILED | Tuesday, January 04, 2011 |
| APPL NO | 12/984451 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Communications: Electrical 340/10.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 31, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
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FUNDED BY
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Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
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ART UNIT
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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