FedInvent™ Patents
Patent Details for Tuesday, January 14, 2014
This page was updated on Monday, March 27, 2023 at 03:55 AM GMT
Department of Health and Human Services (HHS)
US 08628649 | Lindsay et al. |
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FUNDED BY |
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APPLICANT(S) | Stuart Lindsay (Phoenix, Arizona); Jin He (Mesa, Arizona); Peiming Zhang (Gilbert, Arizona); Kevin Reinhart (Chandler, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents Acting for and On Behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Stuart Lindsay (Phoenix, Arizona); Jin He (Mesa, Arizona); Peiming Zhang (Gilbert, Arizona); Kevin Reinhart (Chandler, Arizona) |
ABSTRACT | The present invention is directed to systems, devices and methods for identifying biopolymers, such as strands of DNA, as they pass through a constriction such as a carbon nanotube nanopore. More particularly, the invention is directed to such systems, devices and methods in which a newly translocated portion of the biopolymer forms a temporary electrical circuit between the nanotube nanopore and a second electrode, which may also be a nanotube. Further, the invention is directed to such systems, devices and methods in which the constriction is provided with a functionalized unit which, together with a newly translocated portion of the biopolymer, forms a temporary electrical circuit that can be used to characterize that portion of the biopolymer. |
FILED | Wednesday, March 18, 2009 |
APPL NO | 12/920809 |
ART UNIT | 1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Electrical and wave energy 24/452 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628701 | Mandal et al. |
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APPLICANT(S) | Tarun K. Mandal (Kenner, Louisiana); Richard Graves (Arabi, Louisiana) |
ASSIGNEE(S) | Xavier University of Louisiana (New Orleans, Louisiana) |
INVENTOR(S) | Tarun K. Mandal (Kenner, Louisiana); Richard Graves (Arabi, Louisiana) |
ABSTRACT | A method of preparing micro-capsules. The active ingredient, preferably provided in the form of an acid salt dissolved in a basic aqueous solution, is emulsified into a polymer solution, preferably PLGA in a relatively volatile solvent such as dichloromethane, to create a water in oil emulsion. This emulsion is further emulsified into an aqueous solution having a pH of a between about 7.4 and 8.0 and most preferably between about 7.8 and 8.0 to create a water in oil in water solution. The polymer solvent is allowed to evaporate, causing the emulsified active ingredient and surrounding polymer matrix to precipitate, thereby forming the micro-capsules. The micro-capsules are separated from the suspension, washed and freeze dried. The method has a very high encapsulation efficiency, even at high loading rates. Additionally, the dissolution rate of the micro-particles produced by the method is very steady over a long period of time. |
FILED | Tuesday, October 31, 2006 |
APPL NO | 11/591028 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/4.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628753 | Murthy et al. |
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APPLICANT(S) | Niren Murthy (Atlanta, Georgia); W. Robert Taylor (Stone Mountain, Georgia); Kousik Kundu (Atlanta, Georgia); Sarah F. Knight (Atlanta, Georgia); Sungmun Lee (Dunwoody, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Niren Murthy (Atlanta, Georgia); W. Robert Taylor (Stone Mountain, Georgia); Kousik Kundu (Atlanta, Georgia); Sarah F. Knight (Atlanta, Georgia); Sungmun Lee (Dunwoody, Georgia) |
ABSTRACT | Reduced dyes, such as hydrocyanines, deuterocyanines, and/or other deuterated dyes capable of detecting one or more reactive oxygen species are described herein. The reduced dyes exhibit little or no fluorescence due to the disrupted π conjugation. However, upon reaction with ROS, the reduced dyes are oxidized, regenerating the extended π conjugation and causing a substantial increase in fluorescence intensity. In many case, the oxidized dye is generally membrane impermeable. However, upon reduction, many of the reduced dyes are membrane permeable. Thus, reduced dyes can accumulate in cells and/or tissue to amplify the signal. Once inside the cell or tissue, the reduced dye is reoxidized upon reaction with ROS, and the oxidized dye again becomes membrane impermeable, trapping the dye within the cell. The reduced dyes can be used to image ROS, such as hydroxide radical and superoxide, in serum, cell cultures, tissue explants, and in vivo. |
FILED | Tuesday, September 28, 2010 |
APPL NO | 12/892379 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628767 | Parker et al. |
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APPLICANT(S) | William B. Parker (Birmingham, Alabama); Eric J. Sorscher (Birmingham, Alabama) |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); Southern Research Institute (Birmingham, Alabama) |
INVENTOR(S) | William B. Parker (Birmingham, Alabama); Eric J. Sorscher (Birmingham, Alabama) |
ABSTRACT | A process for inhibiting a mammalian cancerous cell or virally infected cell includes providing a Trichomonas vaginalis purine nucleoside phosphorylase enzyme or a tail mutant purine nucleoside phosphorylase enzyme in proximity to the mammalian cancerous cell or the virally infected cell and exposing the enzyme to a purine nucleoside phosphorylase enzyme cleavable substrate to yield a cytotoxic purine analog. The process includes introducing to the cell a vector containing the phosphorylase enzyme, or a DNA sequence coding for the same and delivering to the cell an effective amount of the substrate such as 9-(β-D-arabinofuranosyl)-2-fluoroadenine (F-araA). |
FILED | Monday, August 17, 2009 |
APPL NO | 13/059178 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628769 | Nelsestuen |
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APPLICANT(S) | Gary L. Nelsestuen (St. Paul, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Gary L. Nelsestuen (St. Paul, Minnesota) |
ABSTRACT | The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described. |
FILED | Monday, December 19, 2011 |
APPL NO | 13/329829 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.640 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628778 | Kim et al. |
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APPLICANT(S) | Kyung Jin Kim (Cupertino, California); Hangil Park (San Francisco, California); Lihong Wang (Palo Alto, California); Maximiliano Vasquez (Palo Alto, California) |
ASSIGNEE(S) | Galaxy Biotech, LLC (Sunnyvale, California) |
INVENTOR(S) | Kyung Jin Kim (Cupertino, California); Hangil Park (San Francisco, California); Lihong Wang (Palo Alto, California); Maximiliano Vasquez (Palo Alto, California) |
ABSTRACT | The present invention is directed toward a humanized neutralizing monoclonal antibody to hepatocyte growth factor, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient. |
FILED | Tuesday, September 29, 2009 |
APPL NO | 12/569463 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/145.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628780 | Valenzuela et al. |
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APPLICANT(S) | Jesus G. Valenzuela (Rockville, Maryland); Jose M. C. Ribeiro (Rockville, Maryland); Aldina Barral (Bahia, Brazil); Manoel Netto (Bahia, Brazil); Claudia Brodskyn (Bahia, Brazil); Regis Gomes (Bahia, Brazil) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Fundação Oswaldo Cruz (FIOCRUZ) (, Brazil) |
INVENTOR(S) | Jesus G. Valenzuela (Rockville, Maryland); Jose M. C. Ribeiro (Rockville, Maryland); Aldina Barral (Bahia, Brazil); Manoel Netto (Bahia, Brazil); Claudia Brodskyn (Bahia, Brazil); Regis Gomes (Bahia, Brazil) |
ABSTRACT | Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed. |
FILED | Wednesday, January 07, 2009 |
APPL NO | 12/350179 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628782 | Berkower |
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FUNDED BY |
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APPLICANT(S) | Ira Berkower (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as Represented by the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Ira Berkower (Washington, District of Columbia) |
ABSTRACT | Disclosed herein are isolated immunogens including variant gp120 polypeptides. In an example, a variant gp120 polypeptide includes a deletion of at least 8 consecutive residues of the fourth conserved loop (C4) between residues 419 and 434 of gp120 according to HXB2 numbering. Also provided are isolated nucleic acid molecules encoding the disclosed isolated immunogens. In an example, an isolated nucleic acid molecule further includes a nucleic acid molecule encoding a hepatitis B surface antigen or a variant thereof. Compositions including the isolated immunogens including variant gp120 polypeptides are also disclosed. In some examples, a composition further includes a carrier protein, such as a hepatitis B surface antigen or a variant thereof (natural or recombinant). Viral-like particles are also provided including any of the disclosed isolated immunogens or compositions. Also disclosed are uses of these variant gp120 polypeptides and nucleic acids encoding variant polypeptides, such as to induce an immune response to HIV-1. |
FILED | Friday, February 26, 2010 |
APPL NO | 12/714085 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/188.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628917 | Bakaletz et al. |
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FUNDED BY |
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APPLICANT(S) | Lauren O. Bakaletz (Hilliard, Ohio); Robert S. Munson, Jr. (Columbus, Ohio); David W. Dyer (Oklahoma City, Oklahoma) |
ASSIGNEE(S) | Nationwide Children's Hospital, Inc. (Columbus, Ohio); The Board of Regents of the University of Oklahoma (Columbus, Ohio); Children's Hosptial Inc. (Columbus, Ohio) |
INVENTOR(S) | Lauren O. Bakaletz (Hilliard, Ohio); Robert S. Munson, Jr. (Columbus, Ohio); David W. Dyer (Oklahoma City, Oklahoma) |
ABSTRACT | The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx. |
FILED | Thursday, July 19, 2012 |
APPL NO | 13/553006 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628935 | Hazen |
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FUNDED BY |
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APPLICANT(S) | Stanley L. Hazen (Pepper Pike, Ohio) |
ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Stanley L. Hazen (Pepper Pike, Ohio) |
ABSTRACT | Provided herein are methods for assessing the risk a test subject with heart failure has of experiencing a major adverse cardiac event, requiring revascularization, requiring a heart transplant, requiring unscheduled hospitalization for heart failure, progression of heart failure status, or any combination thereof. Also provided herein are methods for assessing the risk a test subject has of developing heart failure. The present methods comprise determining the levels of paraoxonase 1 activity in the serum, non-chelated plasma, or both in the test subject and comparing the level of PON1 activity in the test subject's sample with a control or baseline value based on levels of PON1 activity in serum, non-chelated plasma, or both samples from a population of control subjects. Also provided herein are kits useful in assessing such risks. |
FILED | Thursday, August 19, 2010 |
APPL NO | 13/390965 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628962 | Freed et al. |
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APPLICANT(S) | William J. Freed (Bowie, Maryland); Tandis Vazin (Walnut Creek, California) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | William J. Freed (Bowie, Maryland); Tandis Vazin (Walnut Creek, California) |
ABSTRACT | Methods for differentiating stem cells are disclosed herein. These methods can be used to generate neurons, including, but not limited to, dopaminergic neurons. The disclosed methods include culturing stem cells in the absence of fibroblast growth factor-2 to generate embryoid bodies and culturing the embryoid bodies in the presence of an effective amount of at least one of stromal cell-derived factor 1, pleiotrophin, insulin-like growth factor 2, and ephrin B1 on an extracellular matrix for a period of time sufficient to produce dopaminergic neuronal cells. The differentiated cells can be used to study pharmaceutical agents that affect dopaminergic neurons and can be used in the treatment of neurodegenerative disorders such as Parkinson's disease. |
FILED | Wednesday, November 18, 2009 |
APPL NO | 13/129661 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628964 | Lelkes et al. |
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APPLICANT(S) | Peter I. Lelkes (Cherry Hill, New Jersey); Mark J. Mondrinos (Landsdowne, Pennsylvania); Christine M. Finck (Glastonbury, Connecticut) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Peter I. Lelkes (Cherry Hill, New Jersey); Mark J. Mondrinos (Landsdowne, Pennsylvania); Christine M. Finck (Glastonbury, Connecticut) |
ABSTRACT | Isolated mixed populations of fetal pulmonary cells, engineered three-dimensional tissue constructs of these cells, and uses thereof in identifying therapeutic agents which augment, repair, and/or replace dysfunctional native lung and to perform in vitro studies such as pharmaceutical screening, models for lung development and disease and characterization of chemical or mechanical injury are provided. |
FILED | Thursday, October 11, 2007 |
APPL NO | 11/870723 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/395 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628974 | Chen et al. |
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APPLICANT(S) | Xiaoyu Chen (Westlake Village, California); Michael S. Westphall (Fitchburg, Wisconsin); Lloyd M. Smith (Madison, Wisconsin); Brian L. Frey (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Xiaoyu Chen (Westlake Village, California); Michael S. Westphall (Fitchburg, Wisconsin); Lloyd M. Smith (Madison, Wisconsin); Brian L. Frey (Madison, Wisconsin) |
ABSTRACT | A fast and sensitive method and device for protein sequencing are disclosed. The method uses a combination of Edman degradation chemistry and mass spectrometry to sequence proteins and polypeptides. A peptide degradation reaction is performed on a polypeptide or protein ion reactant in the gas phase. The reaction yields a first ion product corresponding to a first amino acid residue of the polypeptide or protein reactant and a polypeptide or protein fragment ion. The mass-to-charge ratio for the first ion product, or the polypeptide or protein fragment ion, or both, is then determined. The first amino acid residue of the polypeptide or protein reactant is then identified from the mass-to-charge ratio so determined. |
FILED | Friday, July 15, 2005 |
APPL NO | 11/568536 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/89 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628977 | Adamec et al. |
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APPLICANT(S) | Jiri Adamec (West Lafayette, Indiana); Wen-Chu Yang (West Lafayette, Indiana); Fred E. Regnier (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Jiri Adamec (West Lafayette, Indiana); Wen-Chu Yang (West Lafayette, Indiana); Fred E. Regnier (West Lafayette, Indiana) |
ABSTRACT | Reagents and methods are provided that permit simultaneous analysis of multiple diverse small molecule analytes present in a complex mixture. Samples are labeled with chemically identical but isotopically distinct forms of the labeling reagent, and analyzed using mass spectrometry. A single reagent simultaneously derivatizes multiple small molecule analytes having different reactive functional groups. |
FILED | Friday, May 01, 2009 |
APPL NO | 12/990560 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629107 | Schiemann et al. |
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APPLICANT(S) | William P. Schiemann (Denver, Colorado); Allan R. Albig (Denver, Colorado) |
ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
INVENTOR(S) | William P. Schiemann (Denver, Colorado); Allan R. Albig (Denver, Colorado) |
ABSTRACT | Disclosed is a panel of biomarkers associated with angiogenesis, and the use of such biomarkers (genes, proteins, homologues and analogs thereof) to regulate angiogenesis. Methods for identifying compounds useful for regulating angiogenesis and conditions related thereto are disclosed. |
FILED | Friday, March 09, 2012 |
APPL NO | 13/417033 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629114 | Walz |
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APPLICANT(S) | Andreas Walz (Pasadena, California) |
ASSIGNEE(S) | Ophidion Inc. (Pasadena, California) |
INVENTOR(S) | Andreas Walz (Pasadena, California) |
ABSTRACT | Compositions and methods are provided including a transporter peptide derived from the loop2 domain of the neuronally-derived lynx1 protein which can be conjugated to an effector agent to form a transporter-effector complex for transport of the therapeutic effector agent to a target that is found across the blood brain barrier. |
FILED | Sunday, June 03, 2012 |
APPL NO | 13/487238 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629116 | Bowen et al. |
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APPLICANT(S) | William S. Bowen (Hamilton, Montana); Jay T. Evans (Hamilton, Montana); Melinda M. Hutton (Hamilton, Montana); David A. Johnson (Hamilton, Montana); Laurie A. Minns (Shoreline, Washington) |
ASSIGNEE(S) | GlaxoSmithKline Biologicals S.A. (Rixensart, Belgium) |
INVENTOR(S) | William S. Bowen (Hamilton, Montana); Jay T. Evans (Hamilton, Montana); Melinda M. Hutton (Hamilton, Montana); David A. Johnson (Hamilton, Montana); Laurie A. Minns (Shoreline, Washington) |
ABSTRACT | The use of a selected aminoalkyl glusoaminide 4-phosphate (AGP) CRX-547 to induce a TRIF biased response in a human system, which results in reduced levels of MyD88-dependent cytokines relative to the MyD88-dependent cytokines induced by its diastereomer AGP CRX-527. |
FILED | Wednesday, December 23, 2009 |
APPL NO | 13/140930 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/25 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629119 | Olson et al. |
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APPLICANT(S) | Eric Olson (Dallas, Texas); Eva van Rooij (Boulder, Colorado) |
ASSIGNEE(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Eric Olson (Dallas, Texas); Eva van Rooij (Boulder, Colorado) |
ABSTRACT | The present invention provides a method of treating or preventing cardiac disorders in a subject in need thereof by inhibiting the expression or function of both miR-499 and miR-208 in the heart cells of the subject. In particular, specific protocols for administering inhibitors of the two miRNAs that achieve efficient, long-term suppression are disclosed. In addition, the invention provides a method for treating or preventing musculoskeletal disorders in a subject in need thereof by increasing the expression or activity of both miR-208 and miR-499 in skeletal muscle cells of the subject. |
FILED | Thursday, February 04, 2010 |
APPL NO | 13/147784 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629141 | Wang et al. |
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APPLICANT(S) | Shaomeng Wang (Saline, Michigan); Wei Sun (Ann Arbor, Michigan); Angelo Aguilar (Ann Arbor, Michigan); Carlos Garcia-Echeverria (Paris, France) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Sanofi (Paris, France) |
INVENTOR(S) | Shaomeng Wang (Saline, Michigan); Wei Sun (Ann Arbor, Michigan); Angelo Aguilar (Ann Arbor, Michigan); Carlos Garcia-Echeverria (Paris, France) |
ABSTRACT | Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases. |
FILED | Friday, May 11, 2012 |
APPL NO | 13/469928 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/232.800 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629170 | Hruby et al. |
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APPLICANT(S) | Dennis E. Hruby (Albany, Oregon); Tove Bolken (N. Keizer, Oregon); Sean M. Amberg (Corvallis, Oregon); Dongcheng Dai (Corvallis, Oregon) |
ASSIGNEE(S) | Siga Technologies, Inc. (New York, New York) |
INVENTOR(S) | Dennis E. Hruby (Albany, Oregon); Tove Bolken (N. Keizer, Oregon); Sean M. Amberg (Corvallis, Oregon); Dongcheng Dai (Corvallis, Oregon) |
ABSTRACT | Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever). |
FILED | Tuesday, October 26, 2010 |
APPL NO | 12/912325 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/394 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629174 | Cavalieri et al. |
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FUNDED BY |
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APPLICANT(S) | Ercole L. Cavalieri (Waterloo, Nebraska); Eleanor G. Rogan (Omaha, Nebraska) |
ASSIGNEE(S) | Prevention L.L.C. (Waterloo, Nebraska) |
INVENTOR(S) | Ercole L. Cavalieri (Waterloo, Nebraska); Eleanor G. Rogan (Omaha, Nebraska) |
ABSTRACT | The present invention relates to methods for preventing the development of cancer or neurodegenerative diseases by administering N-Acetylcysteine (NAC), melatonin, or a combination thereof. The present invention also relates to methods for diagnosing cancer and/or neurdegenerative disease by detecting or determining the amount of dopamine metabolites, 4-CE, 2-CE, methylation of CE or CE-Q conjugates. |
FILED | Friday, July 31, 2009 |
APPL NO | 12/533883 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/418 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629177 | Castor et al. |
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FUNDED BY |
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APPLICANT(S) | Trevor Percival Castor (Arlington, Massachusetts); Geoffrey Purdum (North Attleboro, Massachusetts) |
ASSIGNEE(S) | Aphios Corporation (Woburn, Massachusetts) |
INVENTOR(S) | Trevor Percival Castor (Arlington, Massachusetts); Geoffrey Purdum (North Attleboro, Massachusetts) |
ABSTRACT | Embodiments of the present invention are directed to articles of manufacture and methods of making such articles having utility for the delivery of cannabinoids as a therapeutic. One embodiment of the present invention directed to the article of manufacture comprises a lyophilized particle or sphere having a diameter of about 100 to 500 nanometers having a shell and comprising a biodegradable polymer containing a cannabinoid. A featured cannabinoid is delta-9-tetrahydrocannabinol (delta-9-THC). |
FILED | Tuesday, August 23, 2011 |
APPL NO | 13/216077 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/454 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629253 | Schimmel et al. |
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FUNDED BY |
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APPLICANT(S) | Paul Schimmel (La Jolla, California); Keisuke Wakasugi (Shizuoka, Japan) |
ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
INVENTOR(S) | Paul Schimmel (La Jolla, California); Keisuke Wakasugi (Shizuoka, Japan) |
ABSTRACT | Nucleic acids encoding tRNA synthetase polypeptides useful for regulating angiogenesis are disclosed. Methods of making and using such nucleic acids are also disclosed. |
FILED | Tuesday, October 31, 2006 |
APPL NO | 11/590434 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629260 | Valenzuela et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Jesus G. Valenzuela (Gaithersburg, Maryland); Yasmine Belkaid (Garrett Park, Maryland); Shaden Kamhawi (Rockville, Maryland); David Sacks (Silver Spring, Maryland); Jose M.C. Ribeiro (Rockville, Maryland) |
ABSTRACT | The present disclosure provides methods of selecting and uses of anti-arthropod vector vaccines to prevent Leishmaniasis. The present disclosure also provides compositions for vaccines to prevent Leishmaniasis. |
FILED | Tuesday, December 11, 2012 |
APPL NO | 13/711167 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Organic compounds 536/23.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629283 | Shaw et al. |
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FUNDED BY |
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APPLICANT(S) | Megan L. Shaw (New York, New York); Hans-Heinrich Hoffmann (New York, New York); Adolfo Garcia-Sastre (New York, New York); Peter Palese (New York, New York) |
ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
INVENTOR(S) | Megan L. Shaw (New York, New York); Hans-Heinrich Hoffmann (New York, New York); Adolfo Garcia-Sastre (New York, New York); Peter Palese (New York, New York) |
ABSTRACT | The present invention relates to compounds that modulate the replication of negative-sense, single-stranded RNA viruses, such as influenza virus, and the use of such compounds. The invention relates to methods for increasing the titer of negative-sense, single-stranded RNA viruses, such as influenza virus, in substrates for virus propagation (e.g., tissue culture). The invention also relates to the use of compounds that decrease virus replication as antiviral agents. The invention further relates to methods for identifying compounds that modulate the replication of negative-sense, single-stranded RNA viruses, in particular, influenza virus. |
FILED | Friday, March 06, 2009 |
APPL NO | 12/921077 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 271/113 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629981 | Martini et al. |
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FUNDED BY |
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APPLICANT(S) | Joerg Martini (San Francisco, California); Peter Kiesel (Palo Alto, California); Malte Huck (Munich, Germany); Marshall W. Bern (San Carlos, California); Noble M. Johnson (Menlo Park, California); Michael Bassler (Mainz, Germany); Markus Beck (Munich, Germany) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Joerg Martini (San Francisco, California); Peter Kiesel (Palo Alto, California); Malte Huck (Munich, Germany); Marshall W. Bern (San Carlos, California); Noble M. Johnson (Menlo Park, California); Michael Bassler (Mainz, Germany); Markus Beck (Munich, Germany) |
ABSTRACT | A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions. Time-varying waveforms from sensing results can be compared to obtain spectral differences. |
FILED | Friday, May 20, 2011 |
APPL NO | 13/113021 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/417 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630627 | Davitz et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey Davitz (Danville, California); Sugato Basu (Redwood City, California); Jiye Yu (Menlo Park, California); David Gutelius (Menlo Park, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Jeffrey Davitz (Danville, California); Sugato Basu (Redwood City, California); Jiye Yu (Menlo Park, California); David Gutelius (Menlo Park, California) |
ABSTRACT | In one embodiment, the present invention is a method and apparatus for knowledge generation and deployment in a distributed network. In one embodiment, a method for processing messages in a social network includes receiving a new message from a first node in the network, the new message including a query, providing the first node with an answer to the query, if the answer is located in a repository, and initiating generation of the answer, if the answer is not located in the repository. |
FILED | Tuesday, February 06, 2007 |
APPL NO | 11/671943 |
ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Telecommunications 455/414.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630721 | Gantz |
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FUNDED BY |
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APPLICANT(S) | Bruce J. Gantz (Iowa City, Iowa) |
ASSIGNEE(S) | The University of Iowa (Iowa City, Iowa) |
INVENTOR(S) | Bruce J. Gantz (Iowa City, Iowa) |
ABSTRACT | An electrode array which is able to be inserted to a desired depth within the cochlea to provide useful percepts for the recipient which will also preferably not cause damage to the sensitive structures of the cochlea. The electrode array is insertable through an opening in the cochlea and into at least the basal region of the cochlea and comprises an elongate carrier having a proximal end, a distal end, and a plurality of electrodes supported by the carrier at respective spaced locations thereon in a region between the proximal end and the distal end. A stabilising collar extends outwardly from the elongate carrier at or adjacent a proximal end thereof and has an abutment surface adapted to abut a portion of the cochlea surface around the cochleostomy and at least substantially prevent movement of the carrier following completion of insertion of the array into the cochlea. |
FILED | Thursday, January 26, 2012 |
APPL NO | 13/358629 |
ART UNIT | 3766 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Surgery: Light, thermal, and electrical application 67/137 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630810 | Clermont et al. |
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FUNDED BY |
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APPLICANT(S) | Gilles Clermont (Fombell, Pennsylvania); Patricia A. Hebda (Sarver, Pennsylvania); Yee Key Li (Pittsburgh, Pennsylvania); Qi Mi (Pittsburgh, Pennsylvania); David L. Steed (Pittsburgh, Pennsylvania); Joshua Thomas Sullivan (Butler, Pennsylvania); Katherine Verdolini Abbott (Cheswick, Pennsylvania); Yoram Vodovotz (Sewickley, Pennsylvania); Ivan Petrov Yotov (Pittsburgh, Pennsylvania); Gary An (Chicago, Illinois) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Gilles Clermont (Fombell, Pennsylvania); Patricia A. Hebda (Sarver, Pennsylvania); Yee Key Li (Pittsburgh, Pennsylvania); Qi Mi (Pittsburgh, Pennsylvania); David L. Steed (Pittsburgh, Pennsylvania); Joshua Thomas Sullivan (Butler, Pennsylvania); Katherine Verdolini Abbott (Cheswick, Pennsylvania); Yoram Vodovotz (Sewickley, Pennsylvania); Ivan Petrov Yotov (Pittsburgh, Pennsylvania); Gary An (Chicago, Illinois) |
ABSTRACT | Provided are methods of simulating tissue healing. The methods comprise using a mechanistic computer model of the interrelated effects of inflammation, tissue damage or dysfunction and tissue healing to predict an outcome of healing of damaged tissue in vivo, thereby predicting the outcome of healing of damaged tissue in vivo. Implementations of these methods on a computing device also are provided. Non-limiting examples of diseases and/or conditions that are amenable to simulation according to the methods described herein include: a diabetes, diabetic foot ulcers, necrotizing enterocolitis, ulcerative colitis, Crohn's disease, inflammatory bowel disease, restenosis (post-angioplasty or stent implantation), incisional wounding, excisional wounding, surgery, accidental trauma, pressure ulcer, stasis ulcer, tendon rupture, vocal fold phonotrauma, otitis media and pancreatitis. |
FILED | Monday, March 19, 2012 |
APPL NO | 13/423714 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630966 | Gage et al. |
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FUNDED BY |
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APPLICANT(S) | Fred H. Gage (La Jolla, California); James Bradley Aimone (San Diego, California); Janet Wiles (St. Lucia, Australia) |
ASSIGNEE(S) | Salk Institute for Biological Studies (LaJolla, California) |
INVENTOR(S) | Fred H. Gage (La Jolla, California); James Bradley Aimone (San Diego, California); Janet Wiles (St. Lucia, Australia) |
ABSTRACT | An apparatus, article and method containing an artificial neural network that, after training, produces new trainable nodes such that input data representative of a first event and input data representative of a second event both activate a subset of the new trainable nodes. The artificial neural network can generate an output that is influenced by the input data of both events. In various embodiments, the new trainable nodes are sequentially produced and show decreasing trainability over time such that, at a particular point in time, newer produced nodes are more trainable than earlier produced nodes. The artificial neural network can be included in various embodiments of methods, apparatus and articles for use in predicting or profiling events. |
FILED | Wednesday, January 27, 2010 |
APPL NO | 12/657748 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/082 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 08627673 | Hill et al. |
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FUNDED BY |
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APPLICANT(S) | James W. Hill (Tampa, Florida); Christopher G. Preston (St. Petersburg, Florida); Michael D. Max (St. Pete Beach, Florida) |
ASSIGNEE(S) | Water Generating Systems LLC (Arlington, Virginia) |
INVENTOR(S) | James W. Hill (Tampa, Florida); Christopher G. Preston (St. Petersburg, Florida); Michael D. Max (St. Pete Beach, Florida) |
ABSTRACT | An atmospheric water harvester includes a cooling member over which humid air flows to condense moisture from the atmosphere. The cooling member may be the evaporator of a conventional, gas vapor-based refrigeration circuit. If a gas vapor-based refrigeration circuit is used, the compressor of the circuit may be variable speed. A fan or impeller used to move air through the system may also be variable speed. A preferred embodiment includes a variable flow geometry thermal economizer section configured such that, to varying degrees, the incoming air may be pre-cooled, before it passes over the cooling member, by heat exchange with colder air that has already flowed over the cooling member. |
FILED | Tuesday, March 25, 2008 |
APPL NO | 12/054690 |
ART UNIT | 3744 — SELECT * FROM codes_techcenter; |
CURRENT CPC | Refrigeration 062/291 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08627750 | Ortiz |
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FUNDED BY |
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APPLICANT(S) | Steven A. Ortiz (Lake Elsinore, California) |
ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
INVENTOR(S) | Steven A. Ortiz (Lake Elsinore, California) |
ABSTRACT | A vacuum shroud is provided for receiving nuts separated from frangible collar fasteners by use of a powered offset ratchet head. The shroud comprises of an offset ratchet head receiving portion and a nut receiving portion. The offset ratchet head receiving portion defines an aperture formed to receive and engage the offset ratchet head. The nut receiving portion defines a nut receiving aperture and a nut discharge port. The nut receiving aperture is disposed adjacent to the offset ratchet head receiving aperture, to receive nuts discharged from the offset ratchet head when the ratchet head is disposed in the ratchet head receiving aperture. The shroud may further define a conduit extending from the nut receiving portion to the nut discharge port. The nut discharge port is engageable to a vacuum source to draw nuts received in the nut receiving portion out of the nut discharge port. |
FILED | Tuesday, August 16, 2011 |
APPL NO | 13/211099 |
ART UNIT | 3727 — Printing/Measuring and Testing |
CURRENT CPC | Tools 081/180.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08627770 | Severson |
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FUNDED BY |
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APPLICANT(S) | Gregg J. Severson (Credit River Township, Minnesota) |
ASSIGNEE(S) | BAE Systems Land and Armaments, L.P. (Santa Clara, California) |
INVENTOR(S) | Gregg J. Severson (Credit River Township, Minnesota) |
ABSTRACT | A cartridge assembly for large bore gun systems having an integrated retention assembly for maintaining propellant charges within the cartridge case. The cartridge case having an interior space for receiving propellant charges and an open proximate end through which the propellant charges can be fed. An insulating sleeve defining an interior channel is affixed to the cartridge case and extends out of the proximate end of the cartridge case. The interior channel serves as a chute through which propellant charges can be fed. After the propellant charges are loaded, the insulating sleeve is crimped closed to retain the propellant charges within the cartridge case. A closure plug can be inserted into the proximate end of the cartridge case after the insulating sleeve is crimped closed. |
FILED | Tuesday, June 07, 2011 |
APPL NO | 13/155014 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition and explosives 12/464 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08627771 | Gold |
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FUNDED BY |
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APPLICANT(S) | Vladimir M. Gold (Hillside, New Jersey) |
ASSIGNEE(S) | The United States of America as Reperesented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Vladimir M. Gold (Hillside, New Jersey) |
ABSTRACT | A fragmenting warhead is provided having an outer cylindrically shaped hollow steel shell which can be selectively detonated into different fragment types and sizes. The warhead has a plastic liner within said shell, and a core of explosive. There are a number of insulated wire grids of high electrical resistance which will heat when an electrical current is provided thereto located in intimate thermal contact with the explosive, each grid corresponding to a fragment type and size for selection by providing electrical current to that selected grid. Heat flux is caused when an electrical current runs through a particular grid and this selectively melts explosive in the near vicinity of such grid, then a detonation of the explosive core will result in a fragmentation type and pattern corresponding to that grid type and pattern. An ignition propellant train may also be selectively associated with wires on the grids to further selectively detonate the explosive. The plastic liner serves not only as electrical insulation, but also increases grid structural integrity, ease of manufacturing, thermal insulation, and IM qualities of the warhead. |
FILED | Wednesday, March 14, 2012 |
APPL NO | 13/419801 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ammunition and explosives 12/494 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628055 | Shannon et al. |
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FUNDED BY |
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APPLICANT(S) | Mark A. Shannon (Champaign, Illinois); Byunghoon Bae (Savoy, Illinois); Richard I. Masel (Champaign, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Mark A. Shannon (Champaign, Illinois); Byunghoon Bae (Savoy, Illinois); Richard I. Masel (Champaign, Illinois) |
ABSTRACT | A bi-directional electrostatic microvalve includes a membrane electrode that is controlled by application of voltage to fixed electrodes disposed on either side of the membrane electrode. Dielectric insulating layers separate the electrodes. One of the fixed electrodes defines a microcavity. Microfluidic channels formed into the electrodes provide fluid to the microcavity. A central pad defined in the microcavity places a portion of the second electrode close to the membrane electrode to provide a quick actuation while the microcavity reduces film squeezing pressure of the membrane electrode. In preferred embodiment microvalves, low surface energy and low surface charge trapping coatings, such as fluorocarbon films made from cross-linked carbon di-fluoride monomers or surface monolayers made from fluorocarbon terminated silanol compounds coatings coat the electrode low bulk charge trapping dielectric layers limit charge trapping and other problems and increase device lifetime operation. |
FILED | Tuesday, May 01, 2007 |
APPL NO | 11/797197 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Valves and valve actuation 251/129.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628462 | Berka et al. |
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FUNDED BY |
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APPLICANT(S) | Chris Berka (Carlsbad, California); Djordje Popovic (Carlsbad, California); Gene Davis (Carlsbad, California); Matthew A. Yanagi (Carlsbad, California) |
ASSIGNEE(S) | Advanced Brain Monitoring, Inc. (Carlsbad, California) |
INVENTOR(S) | Chris Berka (Carlsbad, California); Djordje Popovic (Carlsbad, California); Gene Davis (Carlsbad, California); Matthew A. Yanagi (Carlsbad, California) |
ABSTRACT | Systems and methods for optimizing the sleep and post-sleep performance of individuals regardless of their environment and time available for sleep are provided. The systems and methods take into account factors that determine the effects of a sleep episode on dexterity, cognitive functions and the subjective feeling of fatigue after sleeping: duration and sleep architecture of the sleep episode, point on the circadian cycle at which the episode occurred, the amount of sleep debt accumulated prior to the episode and the subject's susceptibility to sleep deprivation. The systems and methods include monitoring of sleep architecture over a longer period of time, measurement of accumulated sleep debt and assessment and/or tailoring of the sleep architecture for each subsequent sleep episode, determining a desired sleep state in which the subject should be in, and generating sensory stimuli for guiding the subject to the desired sleep state. |
FILED | Tuesday, October 06, 2009 |
APPL NO | 12/574631 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/27 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628512 | Kochanek et al. |
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FUNDED BY |
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APPLICANT(S) | Patrick M Kochanek (Pittsburgh, Pennsylvania); Xianren Wu (Pittsburgh, Pennsylvania); Samuel Aaron Tisherman (Pittsburgh, Pennsylvania); S. William Stezoski (Pittsburgh, Pennsylvania); Lyn Yaffe (Woodfield, Maryland) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Patrick M Kochanek (Pittsburgh, Pennsylvania); Xianren Wu (Pittsburgh, Pennsylvania); Samuel Aaron Tisherman (Pittsburgh, Pennsylvania); S. William Stezoski (Pittsburgh, Pennsylvania); Lyn Yaffe (Woodfield, Maryland) |
ABSTRACT | Provided are methods for inducing preservation in a patient and resuscitating that patient. At least three hours of preservation, with successful resuscitation, are realized using the methods described herein. The methods involve flushing a patient with an oxygenated, cold-flush solution, such as normal saline, having an energy source. The patient may be cooled to deep or profound hypothermia to induce preservation. The patient may be resuscitated by warming to from about 33° C. to about 36° C., and then may be slowly warmed over a 24 to 72 hour period to normothermia. Kits for inducing preservation also are provided. |
FILED | Friday, October 08, 2010 |
APPL NO | 12/900917 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Surgery 64/507 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628625 | Witten |
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FUNDED BY |
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APPLICANT(S) | Mark L. Witten (Tucson, Arizona) |
ASSIGNEE(S) | |
INVENTOR(S) | Mark L. Witten (Tucson, Arizona) |
ABSTRACT | A method that uses an L-α-dipalmitoleoyl-phosphatidylcholine (DPPC) surfactant based device that reacts with a substance in a known manner, to detect a substance of interest or to extract a substance of interest from a material is provided. The principles of the present invention are particularly useful in detecting/measuring a substance that is harmful to a human, and also to extracting NACL from saltwater. |
FILED | Monday, October 01, 2007 |
APPL NO | 12/681035 |
ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Cleaning and liquid contact with solids 134/18 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628727 | Van Duyne et al. |
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FUNDED BY |
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APPLICANT(S) | Richard P. Van Duyne (Wilmette, Illinois); Xiaoyu Zhang (Urbana, Illinois); Jing Zhao (Evanston, Illinois); Alyson V. Whitney (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); George C. Schatz (Evanston, Illinois); Peter C. Stair (Northbrook, Illinois); Shengli Zou (Oviedo, Florida); Matthew Young (Allen, Michigan); Olga Lyandres (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Richard P. Van Duyne (Wilmette, Illinois); Xiaoyu Zhang (Urbana, Illinois); Jing Zhao (Evanston, Illinois); Alyson V. Whitney (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); George C. Schatz (Evanston, Illinois); Peter C. Stair (Northbrook, Illinois); Shengli Zou (Oviedo, Florida); Matthew Young (Allen, Michigan); Olga Lyandres (Chicago, Illinois) |
ABSTRACT | The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax). |
FILED | Tuesday, August 28, 2007 |
APPL NO | 11/846352 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/402 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628955 | Kiel et al. |
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FUNDED BY |
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APPLICANT(S) | Johnathan L. Kiel (Brooks City-Base, Texas); Amanda Tijerina (San Antonio, Texas); Eric A. Holwitt (Brooks City-Base, Texas); Jill Parker (Brooks City-Base, Texas); Mark A. Sloan (Spring Branch, Texas); Melanie Woitaske (La Vernia, Texas); Maomian Fan (San Antonio, Texas) |
ASSIGNEE(S) | |
INVENTOR(S) | Johnathan L. Kiel (Brooks City-Base, Texas); Amanda Tijerina (San Antonio, Texas); Eric A. Holwitt (Brooks City-Base, Texas); Jill Parker (Brooks City-Base, Texas); Mark A. Sloan (Spring Branch, Texas); Melanie Woitaske (La Vernia, Texas); Maomian Fan (San Antonio, Texas) |
ABSTRACT | Embodiments herein report compositions, systems and methods for making and using plasmid vectors and nanotube complexes. In certain embodiments, compositions, systems and methods herein include making plasmid vectors having aptamer inserts. In some embodiments, methods disclosed herein may be used to rapidly generate large quantities of plasmid vectors having aptamer inserts directed to a particular target agent. Other aspects concern plasmid constructs associated with organic semiconductors. Yet other aspects concern complexes of nanotubes associated with dsDNA aptamers and tracking molecules. |
FILED | Wednesday, June 02, 2010 |
APPL NO | 12/792492 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628972 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | William C. Tang (Irvine, California); Yu-Hsiang Hsu (Pasadena, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | William C. Tang (Irvine, California); Yu-Hsiang Hsu (Pasadena, California) |
ABSTRACT | A device for identifying infection by the malaria parasite includes a microfluidic device having an inlet and an outlet and a diagnostic channel interposed between the inlet and the outlet. The diagnostic channel includes a contact surface and a sample pump configured to pump a RBC-containing sample into the inlet. The contact surface may be at least one of hydrophilic and roughened. Malaria infected RBCs (miRBCs) interact with the contact surface and become immobilized thereon whereas non-infected RBCs continue to flow downstream in the diagnostic channel. |
FILED | Tuesday, January 10, 2012 |
APPL NO | 13/347551 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/63 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629210 | Webster et al. |
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FUNDED BY |
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APPLICANT(S) | Dean C. Webster (Fargo, North Dakota); Robert J. Pieper (West Bend, Wisconsin); Mohammed J. Nasrullah (Fargo, North Dakota) |
ASSIGNEE(S) | NDSU Research Foundation (Fargo, North Dakota) |
INVENTOR(S) | Dean C. Webster (Fargo, North Dakota); Robert J. Pieper (West Bend, Wisconsin); Mohammed J. Nasrullah (Fargo, North Dakota) |
ABSTRACT | A zwitterionic/amphiphilic pentablock copolymer was prepared using atom transfer radical polymerization (ATRP). The pentablock copolymer is prepared for the atom transfer radical polymerization of a PDMS-PEO-Br macroinitiator and SBMA. The pentablock copolymer is incorporated into a polyurethane coating composition which is useful for antifouling and/or fouling release applications. |
FILED | Friday, October 09, 2009 |
APPL NO | 13/123323 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 524/505 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629389 | Barrows |
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FUNDED BY |
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APPLICANT(S) | Geoffrey Louis Barrows (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Geoffrey Louis Barrows (Washington, District of Columbia) |
ABSTRACT | A monolithic camera configured for a predetermined environment can be made in the following manner. The camera is formed from an integrated circuit that has a light sensitive portion that can sense light from the predetermined environment. Two or more opaque masks are disposed within the oxide layer above the light sensitive pixel array of the image sensor. These opaque masks may be formed from the “metal” layers typically used for signal routing in image sensor integrated circuits. The opaque masks contain arrays of holes arranged so that for each pixel there is a clear path for light to reach the pixel from a corresponding part of the visual field. Each pixel is associated with a different set of holes that allows a different region of the predetermined environment to be observed. |
FILED | Tuesday, March 15, 2011 |
APPL NO | 13/048379 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14643 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
08629398 — Detection beyond the standard radiation noise limit using spectrally selective absorption
US 08629398 | Talghader et al. |
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FUNDED BY |
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APPLICANT(S) | Joseph J. Talghader (Edina, Minnesota); Ryan P. Shea (St. Paul, Minnesota); Anand S. Gawarikar (Minneapolis, Minnesota) |
ASSIGNEE(S) | The Regents of the University of Minnesota (St. Paul, Minnesota) |
INVENTOR(S) | Joseph J. Talghader (Edina, Minnesota); Ryan P. Shea (St. Paul, Minnesota); Anand S. Gawarikar (Minneapolis, Minnesota) |
ABSTRACT | High sensitivity thermal detectors that perform beyond the blackbody radiation noise limit are described. Thermal detectors, as described herein, use spectrally selective materials that absorb strongly in the wavelength region of the desired signal but only weakly or not at all in the primary thermal emission band. Exemplary devices that can be made in accordance with the present invention include microbolometers containing semiconductors that absorb in the MWIR and/or THz range but not the LWIR. |
FILED | Friday, May 29, 2009 |
APPL NO | 12/996704 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/338.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629423 | Kislov |
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FUNDED BY |
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APPLICANT(S) | Nikolai Kislov (Tampa, Florida) |
ASSIGNEE(S) | |
INVENTOR(S) | Nikolai Kislov (Tampa, Florida) |
ABSTRACT | In the present invention, one or more inventive designs and techniques allow formation of high speed complementary metal oxide semiconductor (CMOS) process compatible tunneling devices that are formed on low dielectric loss sheet-substrates (such as silicon or germanium for infrared or quartz and sapphire for visible or near infrared) having the first and the second smooth planar surfaces and an intermediate surface in the form of a hole, or slit, or a side edge, which extends between and connects the first and second surfaces, so that deposited from opposite sides of the sheet-substrate the first metal layer followed by its oxidation or nanometer thickness tunneling dielectric coating and the second metal layer have an overlapped coupled area within the intermediate surface, thus forming a non-planar metal-insulator-metal (MIM) tunneling junction of low capacitance and high cut-off frequency, which is capable to operate at room temperature at terahertz, infrared, and even optical frequencies. Also included are methods of preparation of the non-planar MIM tunneling devices of the present invention as well as examples of practical applicability for manufacturing the devices for both reception and generation of terahertz, infrared, and optical radiation. |
FILED | Wednesday, June 10, 2009 |
APPL NO | 12/455967 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629480 | Nayfeh et al. |
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FUNDED BY |
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APPLICANT(S) | Osama M. Nayfeh (Adelphi, Maryland); Madan Dubey (South River, New Jersey) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Osama M. Nayfeh (Adelphi, Maryland); Madan Dubey (South River, New Jersey) |
ABSTRACT | A hetero-junction tunneling transistor having a first layer of p++ silicon germanium which forms a source for the transistor at one end. A second layer of n+ silicon material is deposited so that a portion of the second layer overlies the first layer and forms the drain for the transistor. An insulating layer and metallic gate for the transistor is deposited on top of the second layer so that the gate is aligned with the overlying portions of the first and second layers. The gate voltage controls the conduction between the source and the drain and the conduction between the first and second layers occurs by vertical tunneling between the layers. |
FILED | Thursday, May 24, 2012 |
APPL NO | 13/479392 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/192 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629600 | Symko et al. |
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FUNDED BY |
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APPLICANT(S) | Orest G. Symko (Salt Lake City, Utah); Ivan A. Rodriguez (Salt Lake City, Utah); Ryan Behunin (Salt Lake City, Utah); Marie Urry (Centerville, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Orest G. Symko (Salt Lake City, Utah); Ivan A. Rodriguez (Salt Lake City, Utah); Ryan Behunin (Salt Lake City, Utah); Marie Urry (Centerville, Utah) |
ABSTRACT | A thermoacoustic energy converter for converting heat energy to electricity includes an annular resonator with a regenerator disposed therein. An electro-mechanical transducer is coupled to the annular resonator and in fluid communication with the working fluid. When heat is applied to one end of the annular resonator, a traveling acoustic wave is generated in the annular resonator causing vibrations in the working fluid that actuate the electro-mechanical transducer to generate electricity. |
FILED | Monday, May 10, 2010 |
APPL NO | 12/777095 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/113 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629701 | Ferriss et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Mark A. Ferriss (Tarrytown, New York); Arun Natarajan (White Plains, New York); Benjamin Parker (Peekskill, New York); Alexander Rylyakov (Mount Kisco, New York); Jose A. Tierno (Palo Alto, California); Soner Yaldiz (Pittsburgh, New York) |
ABSTRACT | A method and system for compensating for offsets when measuring parameters of a phase-locked loop (PLL). In one embodiment, a proportional path in the PLL is temporarily shut off, a measurement is made of a real time-to-zero crossing in the PLL to measure a defined parameter of the PLL, the proportional path is switched on, and the defined loop parameter is adjusted based on this measurement. In one embodiment, the real time-to-zero crossing is measured after introducing a phase step into the PLL between a reference signal and an output signal of the PLL. In an embodiment, two phase steps, having opposite polarities, are successively introduced into the PLL, and the time-to-crossing measurements resulting from these two phase steps may be averaged, and this average is used to determine a loop parameter. |
FILED | Monday, July 22, 2013 |
APPL NO | 13/947664 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/156 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629729 | Hoppensteadt et al. |
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FUNDED BY |
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APPLICANT(S) | Frank C. Hoppensteadt (Carefree, Arizona); Andrew D. Kent (New York, New York); Ferran Macià Bros (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Frank C. Hoppensteadt (Carefree, Arizona); Andrew D. Kent (New York, New York); Ferran Macià Bros (New York, New York) |
ABSTRACT | A nano-oscillator magnetic wave propagation system has a group of aggregated spin-torque nano-oscillators (ASTNOs), which share a magnetic propagation material. Each of the group of ASTNOs is disposed about an emanating point in the magnetic propagation material. During a non-wave propagation state of the nano-oscillator magnetic wave propagation system, the magnetic propagation material receives a polarizing magnetic field. During a wave propagation state of the nano-oscillator magnetic wave propagation system, each of the group of ASTNOs initiates spin waves through the magnetic propagation material, such that a portion of the spin waves initiated from each of the group of ASTNOs combine to produce an aggregation of spin waves emanating from the emanating point. The aggregation of spin waves may provide a sharper wave front than wave fronts of the individual spin waves initiated from each of the group of ASTNOs. |
FILED | Thursday, July 21, 2011 |
APPL NO | 13/187724 |
ART UNIT | 2817 — Semiconductors/Memory |
CURRENT CPC | Oscillators 331/94.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629975 | Dierking et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew P. Dierking (Springfield, Ohio); Bradley D. Duncan (Dayton, Ohio) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Matthew P. Dierking (Springfield, Ohio); Bradley D. Duncan (Dayton, Ohio) |
ABSTRACT | A multi-function, range-Doppler, synthetic aperture and micro-Doppler, coherent laser radar system having improved spatial resolution and immunity to undesired platform motion utilizing two or more simultaneous, spatially offset transceiver apertures. |
FILED | Wednesday, August 18, 2010 |
APPL NO | 12/858680 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Optics: Measuring and testing 356/4.10 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629978 | Estevadeordal et al. |
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FUNDED BY |
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APPLICANT(S) | Jordi Estevadeordal (Saratoga Springs, New York); Christopher Marks (Waynesville, Ohio); Rolf Sondergaard (Beavercreek, Ohio); James M. Wolff (Huber Heights, Ohio) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Jordi Estevadeordal (Saratoga Springs, New York); Christopher Marks (Waynesville, Ohio); Rolf Sondergaard (Beavercreek, Ohio); James M. Wolff (Huber Heights, Ohio) |
ABSTRACT | Three-dimensional surface illumination using curved laser sheets is described for optical flow measurements over conformal curved surfaces. The illumination method is applicable to many different optical-based flow visualization and measurement techniques, particularly for particle image velocimetry. An alignment sheet increases the accuracy of determining the position and movement of particles used in optical-base fluid flow techniques. |
FILED | Wednesday, January 05, 2011 |
APPL NO | 12/985160 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Optics: Measuring and testing 356/28 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630308 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Xiaodong Wang (New York, New York); Alberto Lopez Toledo (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Xiaodong Wang (New York, New York); Alberto Lopez Toledo (New York, New York) |
ABSTRACT | Methods and apparatuses for detecting deviations from legitimate operation on a wireless network. The method includes detecting a sequence of observable events related to operation of an entity in the wireless network, and determining from the detected sequence of observable events for a particular entity in the wireless network what number of idle slots occurred between two consecutive observable events to provide a first output. The method further includes obtaining a second output corresponding to the number of idle slots between two consecutive observable events for legitimate operation of any entity in the wireless network using the network transmission protocol, and comparing a function of the first output with a function of the second output to determine whether or not the particular entity is deviating from legitimate operation of the network transmission protocol. |
FILED | Thursday, April 26, 2007 |
APPL NO | 11/796499 |
ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Multiplex communications 370/458 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630519 | Sorin et al. |
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FUNDED BY |
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APPLICANT(S) | Fabien Sorin (Paris, France); Guillaume Lestoquoy (Cambridge, Massachusetts); Sylvain Danto (Clemson, Massachusetts); Yoel Fink (Brookline, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Fabien Sorin (Paris, France); Guillaume Lestoquoy (Cambridge, Massachusetts); Sylvain Danto (Clemson, Massachusetts); Yoel Fink (Brookline, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts) |
ABSTRACT | Photodetecting fiber. The fiber detects and localizes an incident optical beam. A semiconducting core is in intimate contact with a material forming a resistive channel that breaks axial symmetry. The resistive channel has a resistivity between that of metals and the semiconducting core, enabling the imposition of non-uniform, convex electric potential distributions along the fiber axis allowing photo-current measurements along the fiber. |
FILED | Wednesday, October 05, 2011 |
APPL NO | 13/253200 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical waveguides 385/101 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630627 | Davitz et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey Davitz (Danville, California); Sugato Basu (Redwood City, California); Jiye Yu (Menlo Park, California); David Gutelius (Menlo Park, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Jeffrey Davitz (Danville, California); Sugato Basu (Redwood City, California); Jiye Yu (Menlo Park, California); David Gutelius (Menlo Park, California) |
ABSTRACT | In one embodiment, the present invention is a method and apparatus for knowledge generation and deployment in a distributed network. In one embodiment, a method for processing messages in a social network includes receiving a new message from a first node in the network, the new message including a query, providing the first node with an answer to the query, if the answer is located in a repository, and initiating generation of the answer, if the answer is not located in the repository. |
FILED | Tuesday, February 06, 2007 |
APPL NO | 11/671943 |
ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Telecommunications 455/414.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630807 | Edman et al. |
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FUNDED BY |
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APPLICANT(S) | Carl F. Edman (San Diego, California); Michael J. Heller (Encinitas, California); Rachel Formosa (San Diego, California); Christian Gurtner (La Jolla, California) |
ASSIGNEE(S) | Gamida For Life B.V. (Rotterdam, Netherlands) |
INVENTOR(S) | Carl F. Edman (San Diego, California); Michael J. Heller (Encinitas, California); Rachel Formosa (San Diego, California); Christian Gurtner (La Jolla, California) |
ABSTRACT | Methods are provided for the fabrication of microscale, including micron and sub-micron scale, including nanoscale, devices. Electronic transport of movable component devices is utilized through a fluidic medium to effect transport to a desired target location on a substrate or motherboard. Forces include electrophoretic force, electroosmotic force, electrostatic force and/or dielectrophoretic force. In the preferred embodiment, free field electroosmotic forces are utilized either alone, or in conjunction with, other forces. These forces may be used singly or in combination, as well as in conjunction with yet other forces, such as fluidic forces, mechanical forces or thermal convective forces. Transport may be effected through the use of driving electrodes so as to transport the component device to yet other connection electrodes. In certain embodiments, the component devices may be attached to the target device using a solder reflow step. |
FILED | Tuesday, April 11, 2006 |
APPL NO | 11/401713 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630837 | Green et al. |
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FUNDED BY |
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APPLICANT(S) | Harley S. Green (El Segundo, California); Joshua D. Train (Chantilly, Virginia) |
ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
INVENTOR(S) | Harley S. Green (El Segundo, California); Joshua D. Train (Chantilly, Virginia) |
ABSTRACT | Systems and methods for emulating the reception of a multicast message considering simulated host channel characteristics. Methods, according to various embodiments, may comprise executing a plurality of host applications subscribing to a first multicast group address. The methods may also comprise executing a plurality of sockets. The methods may also comprise receiving a data packet indicating the first multicast group address. The data packet may be modified according to a first channel impairment condition to generate a first impaired data packet, which may be directed to a first host application selected from the plurality of host applications via a first socket selected from the plurality of sockets. The first socket may correspond to the first host. The data packet may be modified according to a second channel impairment condition to generate a second impaired data packet directed to a second host application via a second socket. |
FILED | Thursday, June 17, 2010 |
APPL NO | 12/802954 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/23 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08631031 | Kepner |
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FUNDED BY |
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APPLICANT(S) | Jeremy V. Kepner (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Jeremy V. Kepner (Cambridge, Massachusetts) |
ABSTRACT | An associative array stores data in a matrix form responsive to linear algebra operations. A set of associative arrays employed for representing data are each composable, such that operations performed on them generate a result that is also an associative array responsive to linear algebra operations. An algebraic engine implements standard linear algebra computations for performing database operations. In contrast to conventional relational models, the associative arrays are not bound by a rigid schema and transaction atomicity, which tend to impose transactional overhead. The associative arrays store only non-null entries as tuples. The tuples, are responsive to linear algebra operations, which employ simpler coding constructs than conventional relational SQL or other access mechanisms. The associative arrays and algebraic engine enjoy relaxed consistency, which recognizes that many queries seek information that is malleable over time, and need not rely on global consistency or transaction atomicity in order to retrieve useful results. |
FILED | Wednesday, January 19, 2011 |
APPL NO | 13/009100 |
ART UNIT | 2157 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/769 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08631248 | Cowan et al. |
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FUNDED BY |
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APPLICANT(S) | Stanley Crispin Cowan (Portland, Oregon); Seth Richard Arnold (Lake Oswego, Oregon); Steven Michael Beattie (Portland, Oregon); Perry Michael Wagle (Hillsboro, Oregon) |
ASSIGNEE(S) | Apple Inc. (Cupertino, California) |
INVENTOR(S) | Stanley Crispin Cowan (Portland, Oregon); Seth Richard Arnold (Lake Oswego, Oregon); Steven Michael Beattie (Portland, Oregon); Perry Michael Wagle (Hillsboro, Oregon) |
ABSTRACT | To protect computer programs against security attacks that attempt to corrupt pointers within the address space of the program, the value of a pointer is encrypted each time the pointer is initialized or modified, and then the value is decrypted before use, i.e., each time the pointer is read. Preferably, the encrypting and decrypting steps are effected by instructions generated by a compiler during compilation of the program. One convenient method of implementing the encrypting and decrypting steps is by XOR'ing the pointer with a predetermined encryption key value, which could be specially selected or selected at random. |
FILED | Wednesday, October 31, 2007 |
APPL NO | 11/932517 |
ART UNIT | 2493 — Cryptography and Security |
CURRENT CPC | Electrical computers and digital processing systems: Support 713/190 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 08627654 | Roos et al. |
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FUNDED BY |
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APPLICANT(S) | Bryan Nathaniel Roos (West Bloomfield, Michigan); Eugene V. Gonze (Pinckney, Michigan); Halim G. Santoso (Novi, Michigan); Brian L. Spohn (Holly, Michigan) |
ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
INVENTOR(S) | Bryan Nathaniel Roos (West Bloomfield, Michigan); Eugene V. Gonze (Pinckney, Michigan); Halim G. Santoso (Novi, Michigan); Brian L. Spohn (Holly, Michigan) |
ABSTRACT | A method of treating emissions from an internal combustion engine of a hybrid vehicle includes directing a flow of air created by the internal combustion engine when the internal combustion engine is spinning but not being fueled through a hydrocarbon absorber to collect hydrocarbons within the flow of air. When the hydrocarbon absorber is full and unable to collect additional hydrocarbons, the flow of air is directed through an electrically heated catalyst to treat the flow of air and remove the hydrocarbons. When the hydrocarbon absorber is not full and able to collect additional hydrocarbons, the flow of air is directed through a bypass path that bypasses the electrically heated catalyst to conserve the thermal energy stored within the electrically heated catalyst. |
FILED | Tuesday, August 02, 2011 |
APPL NO | 13/196263 |
ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
CURRENT CPC | Power plants 060/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08627901 | Underwood et al. |
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FUNDED BY |
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APPLICANT(S) | Lance D. Underwood (Morrison, Colorado); Ryan J. Norton (Lone Tree, Colorado); Ryan P. McKay (Littleton, Colorado); David R. Mesnard (Boulder, Colorado); Jason D. Fraze (Littleton, Colorado); Mark S. Zediker (Castle Rock, Colorado); Brian O. Faircloth (Evergreen, Colorado) |
ASSIGNEE(S) | Foro Energy, Inc. (Littleton, Colorado) |
INVENTOR(S) | Lance D. Underwood (Morrison, Colorado); Ryan J. Norton (Lone Tree, Colorado); Ryan P. McKay (Littleton, Colorado); David R. Mesnard (Boulder, Colorado); Jason D. Fraze (Littleton, Colorado); Mark S. Zediker (Castle Rock, Colorado); Brian O. Faircloth (Evergreen, Colorado) |
ABSTRACT | There is provided for laser bottom hole assembly for providing a high power laser beam having greater than 5 kW of power for a laser mechanical drilling process to advance a borehole. This assembly utilizes a reverse Moineau motor type power section and provides a self-regulating system that addresses fluid flows relating to motive force, cooling and removal of cuttings. |
FILED | Friday, October 01, 2010 |
APPL NO | 12/896021 |
ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Boring or penetrating the earth 175/16 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628603 | Martin et al. |
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FUNDED BY |
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APPLICANT(S) | Christopher L. Martin (Grand Forks, North Dakota); Ye Zhuang (Grand Forks, North Dakota) |
ASSIGNEE(S) | Energy and Enviromental Research Center Foundation (Grand Forks, North Dakota) |
INVENTOR(S) | Christopher L. Martin (Grand Forks, North Dakota); Ye Zhuang (Grand Forks, North Dakota) |
ABSTRACT | A method for treating a process gas with a liquid comprises contacting a process gas with a hygroscopic working fluid in order to remove a constituent from the process gas. A system for treating a process gas with a liquid comprises a hygroscopic working fluid comprising a component adapted to absorb or react with a constituent of a process gas, and a liquid-gas contactor for contacting the working fluid and the process gas, wherein the constituent is removed from the process gas within the liquid-gas contactor. |
FILED | Friday, September 23, 2011 |
APPL NO | 13/241624 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/188 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628614 | Stoddard |
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FUNDED BY |
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APPLICANT(S) | Nathan G. Stoddard (Frederick, Maryland) |
ASSIGNEE(S) | AMG IdealCast Solar Corporation (Wayne, Pennsylvania) |
INVENTOR(S) | Nathan G. Stoddard (Frederick, Maryland) |
ABSTRACT | Methods and apparatuses are provided for casting silicon for photovoltaic cells and other applications. With such methods and apparatuses, a cast body of monocrystalline silicon may be formed that is free of, or substantially free of, radially-distributed impurities and defects and having at least two dimensions that are each at least about 35 cm is provided. |
FILED | Wednesday, October 19, 2011 |
APPL NO | 13/276700 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/81 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628705 | Dai et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Sheng Dai (Knoxville, Tennessee); Georges A. Guiochon (Farragut, Tennessee); Chengdu Liang (Knoxville, Tennessee) |
ABSTRACT | A carbon monolith includes a robust carbon monolith characterized by a skeleton size of at least 100 nm, and a hierarchical pore structure having macropores and mesopores. |
FILED | Tuesday, January 15, 2013 |
APPL NO | 13/741745 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/49 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628727 | Van Duyne et al. |
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FUNDED BY |
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APPLICANT(S) | Richard P. Van Duyne (Wilmette, Illinois); Xiaoyu Zhang (Urbana, Illinois); Jing Zhao (Evanston, Illinois); Alyson V. Whitney (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); George C. Schatz (Evanston, Illinois); Peter C. Stair (Northbrook, Illinois); Shengli Zou (Oviedo, Florida); Matthew Young (Allen, Michigan); Olga Lyandres (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Richard P. Van Duyne (Wilmette, Illinois); Xiaoyu Zhang (Urbana, Illinois); Jing Zhao (Evanston, Illinois); Alyson V. Whitney (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); George C. Schatz (Evanston, Illinois); Peter C. Stair (Northbrook, Illinois); Shengli Zou (Oviedo, Florida); Matthew Young (Allen, Michigan); Olga Lyandres (Chicago, Illinois) |
ABSTRACT | The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax). |
FILED | Tuesday, August 28, 2007 |
APPL NO | 11/846352 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/402 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628871 | Frey et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew H. Frey (Cottage Grove, Minnesota); Daniel M. Pierpont (North St. Paul, Minnesota); Steven J. Hamrock (Stillwater, Minnesota) |
ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
INVENTOR(S) | Matthew H. Frey (Cottage Grove, Minnesota); Daniel M. Pierpont (North St. Paul, Minnesota); Steven J. Hamrock (Stillwater, Minnesota) |
ABSTRACT | A fuel cell membrane electrode assembly is provided comprising a polymer electrolyte membrane which comprises a polymer that comprises bound anionic functional groups, wherein the polymer electrolyte membrane additionally comprises cerium cations. In another aspect, a fuel cell membrane electrode assembly is provided comprising a polymer electrolyte membrane which comprises a polymer that comprises bound anionic functional groups, wherein at least a portion of the anionic functional groups are in acid form and at least a portion of the anionic functional groups are neutralized by cerium cations. In another aspect, a polymer electrolyte membrane is provided which comprises a polymer that comprises bound anionic functional groups, wherein the polymer electrolyte membrane additionally comprises cerium cations, and wherein the amount of cerium cations present is between 0.001 and 0.5 charge equivalents based on the molar amount of acid functional groups present in the polymer electrolyte, more typically between 0.005 and 0.2, more typically between 0.01 and 0.1, and more typically between 0.02 and 0.05. |
FILED | Friday, October 28, 2005 |
APPL NO | 11/262268 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/33 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628880 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Liyu Li (Richland, Washington); Soowhan Kim (Richland, Washington); Zhenguo Yang (Richland, Washington); Wei Wang (Richland, Washington); Jianlu Zhang (Richland, Washington); Baowei Chen (Richland, Washington); Zimin Nie (Richland, Washington); Guanguang Xia (Pasco, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Liyu Li (Richland, Washington); Soowhan Kim (Richland, Washington); Zhenguo Yang (Richland, Washington); Wei Wang (Richland, Washington); Jianlu Zhang (Richland, Washington); Baowei Chen (Richland, Washington); Zimin Nie (Richland, Washington); Guanguang Xia (Pasco, Washington) |
ABSTRACT | Redox flow battery systems having a supporting solution that contains Cl− ions can exhibit improved performance and characteristics. Furthermore, a supporting solution having mixed SO42− and Cl− ions can provide increased energy density and improved stability and solubility of one or more of the ionic species in the catholyte and/or anolyte. According to one example, a vanadium-based redox flow battery system is characterized by an anolyte having V2+ and V3+ in a supporting solution and a catholyte having V4+ and V5+ in a supporting solution. The supporting solution can contain Cl− ions or a mixture of SO42− and Cl− ions. |
FILED | Tuesday, September 28, 2010 |
APPL NO | 12/892693 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/199 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628891 | Brown et al. |
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FUNDED BY |
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APPLICANT(S) | Michael Brown (Cambridge, Massachusetts); Norman F. Bessette, II (Middleboro, Massachusetts); Anthony F. Litka (Hanover, Massachusetts); Douglas S. Schmidt (Walpole, Massachusetts) |
ASSIGNEE(S) | Acumentrics Corporation (Westwood, Massachusetts) |
INVENTOR(S) | Michael Brown (Cambridge, Massachusetts); Norman F. Bessette, II (Middleboro, Massachusetts); Anthony F. Litka (Hanover, Massachusetts); Douglas S. Schmidt (Walpole, Massachusetts) |
ABSTRACT | A system and method for electrically interconnecting a plurality of fuel cells to provide dense packing of the fuel cells. Each one of a plurality of fuel cells has a plurality of discrete electrical connection points along an outer surface. Electrical connections are made directly between the discrete electrical connection points of adjacent fuel cells so that the fuel cells can be packed more densely. Fuel cells have at least one outer electrode and at least one discrete interconnection to an inner electrode, wherein the outer electrode is one of a cathode and an anode and wherein the inner electrode is the other of the cathode and the anode. In tubular solid oxide fuel cells the discrete electrical connection points are spaced along the length of the fuel cell. |
FILED | Thursday, December 14, 2006 |
APPL NO | 11/639361 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/466 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628970 | Schabron et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Wyoming Research Corporation d/b/a Western Research Institute (Laramie, Wyoming) |
ASSIGNEE(S) | The University of Wyoming Research Corporation (Laramie, Wyoming) |
INVENTOR(S) | John F. Schabron (Laramie, Wyoming); Joseph F. Rovani, Jr. (Laramie, Wyoming) |
ABSTRACT | Disclosed herein is a method involving the steps of (a) precipitating an amount of asphaltenes from a liquid sample of a first hydrocarbon-containing feedstock having solvated asphaltenes therein with one or more first solvents in a column; (b) determining one or more solubility characteristics of the precipitated asphaltenes; (c) analyzing the one or more solubility characteristics of the precipitated asphaltenes; and (d) correlating a measurement of feedstock reactivity for the first hydrocarbon-containing feedstock sample with a mathematical parameter derived from the results of analyzing the one or more solubility characteristics of the precipitated asphaltenes. Determined parameters and processabilities for a plurality of feedstocks can be used to generate a mathematical relationship between parameter and processability; this relationship can be used to estimate the processability for hydroprocessing for a feedstock of unknown processability. |
FILED | Tuesday, June 04, 2013 |
APPL NO | 13/909780 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/29 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628977 | Adamec et al. |
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FUNDED BY |
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APPLICANT(S) | Jiri Adamec (West Lafayette, Indiana); Wen-Chu Yang (West Lafayette, Indiana); Fred E. Regnier (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Jiri Adamec (West Lafayette, Indiana); Wen-Chu Yang (West Lafayette, Indiana); Fred E. Regnier (West Lafayette, Indiana) |
ABSTRACT | Reagents and methods are provided that permit simultaneous analysis of multiple diverse small molecule analytes present in a complex mixture. Samples are labeled with chemically identical but isotopically distinct forms of the labeling reagent, and analyzed using mass spectrometry. A single reagent simultaneously derivatizes multiple small molecule analytes having different reactive functional groups. |
FILED | Friday, May 01, 2009 |
APPL NO | 12/990560 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629076 | Worsley et al. |
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FUNDED BY |
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APPLICANT(S) | Marcus A. Worsley (Hayward, California); Joshua D. Kuntz (Livermore, California); Theodore F. Baumann (Discover Bay, California); Joe H. Satcher, Jr. (Patterson, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Marcus A. Worsley (Hayward, California); Joshua D. Kuntz (Livermore, California); Theodore F. Baumann (Discover Bay, California); Joe H. Satcher, Jr. (Patterson, California) |
ABSTRACT | A metal oxide-carbon composite includes a carbon aerogel with an oxide overcoat. The metal oxide-carbon composite is made by providing a carbon aerogel, immersing the carbon aerogel in a metal oxide sol under a vacuum, raising the carbon aerogel with the metal oxide sol to atmospheric pressure, curing the carbon aerogel with the metal oxide sol at room temperature, and drying the carbon aerogel with the metal oxide sol to produce the metal oxide-carbon composite. The step of providing a carbon aerogel can provide an activated carbon aerogel or provide a carbon aerogel with carbon nanotubes that make the carbon aerogel mechanically robust. Carbon aerogels can be coated with sol-gel silica and the silica can be converted to silicon carbide, improving the thermal stability of the carbon aerogel. |
FILED | Friday, March 18, 2011 |
APPL NO | 13/051915 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629098 | Fahmy et al. |
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FUNDED BY |
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APPLICANT(S) | Tarek Fahmy (New Haven, Connecticut); Erin Steenblock (Janesville, Wisconsin) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Tarek Fahmy (New Haven, Connecticut); Erin Steenblock (Janesville, Wisconsin) |
ABSTRACT | Modular aAPCs and methods of their manufacture and use are provided. The modular aAPCs are constructed from polymeric microparticles. The aAPCs include encapsulated cytokines and coupling agents which modularly couple functional elements including T cell receptor activators, co-stimulatory molecules and adhesion molecules to the particle. The ability of these aAPCs to release cytokines in a controlled manner, coupled with their modular nature and ease of ligand attachment, results in an ideal, tunable APC capable of stimulating and expanding primary T cells. |
FILED | Wednesday, January 14, 2009 |
APPL NO | 12/812304 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629121 | Konowalchuk et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas W. Konowalchuk (Newport, Oregon) |
ASSIGNEE(S) | World Force Technologies, LLC (Newport, Oregon) |
INVENTOR(S) | Thomas W. Konowalchuk (Newport, Oregon); Jack Konowalchuk (Newport, Oregon) |
ABSTRACT | This invention provides a high molecular weight polysaccharide capable of binding to and inhibiting virus and related pharmaceutical formulations and methods of inhibiting viral infectivity and/or pathogenicity, as well as immunogenic compositions. The invention further includes methods of inhibiting the growth of cancer cells and of ameliorating a symptom of aging. Additionally, the invention provides methods of detecting and/or quantifying and/or isolating viruses. |
FILED | Tuesday, January 26, 2010 |
APPL NO | 12/694226 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629239 | Semrau et al. |
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FUNDED BY |
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APPLICANT(S) | Jeremy D. Semrau (Ann Arbor, Michigan); Warren Gallagher (Eau Claire, Wisconsin); Sukhwan Yoon (Ann Arbor, Michigan); Jeongdae Im (Ann Arbor, Michigan); Alan A. DiSpirito (Ames, Iowa); Sung-Woo Lee (Hillsboro, Oregon); Scott Hartsel (Eau Claire, Wisconsin); Marcus T. McEllistrem (Eau Claire, Wisconsin) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); The Regents of the University of Michigan (Ann Arbor, Michigan); WiSys Technology Foundation (Madison, Wisconsin) |
INVENTOR(S) | Jeremy D. Semrau (Ann Arbor, Michigan); Warren Gallagher (Eau Claire, Wisconsin); Sukhwan Yoon (Ann Arbor, Michigan); Jeongdae Im (Ann Arbor, Michigan); Alan A. DiSpirito (Ames, Iowa); Sung-Woo Lee (Hillsboro, Oregon); Scott Hartsel (Eau Claire, Wisconsin); Marcus T. McEllistrem (Eau Claire, Wisconsin) |
ABSTRACT | The present disclosures provides isolated or purified compounds, each of which bind to a metal atom. Generally, the compounds are small in size (e.g, molecular weight of less than about 1 kDa) and peptidic in nature, inasmuch as the compounds comprise amino acids. In some embodiments, the compound comprises a structure of Formula I: M1-P1-M2-P2 wherein each of P1 and P2 is a peptide comprising at least two amino acids, M1 is a first metal binding moiety comprising a substituted imidazolone ring, M2 is a second metal binding moiety comprising a substituted oxazolone ring, and wherein M1 and M2 bind to a single metal atom. Also provided are related complexes, conjugates, cells which synthesize the compounds of the present disclosures, substantially homogenous cultures thereof, kits and compositions, and methods of making or using the materials of the present disclosures. |
FILED | Thursday, August 04, 2011 |
APPL NO | 13/198669 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629255 | Brown et al. |
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FUNDED BY |
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APPLICANT(S) | Steven Brown (Knoxville, Tennessee); Adam Guss (Knoxville, Tennessee); Shihui Yang (Knoxville, Tennessee); Tatiana Karpinets (Louisville, Tennessee); Lee Lynd (Meriden, New Hampshire); Xiongjun Shao (White River Junction, Vermont) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Steven Brown (Knoxville, Tennessee); Adam Guss (Knoxville, Tennessee); Shihui Yang (Knoxville, Tennessee); Tatiana Karpinets (Louisville, Tennessee); Lee Lynd (Meriden, New Hampshire); Xiongjun Shao (White River Junction, Vermont) |
ABSTRACT | The present invention provides isolated nucleic acid molecules which encode a mutant acetaldehyde-CoA/alcohol dehydrogenase or mutant alcohol dehydrogenase and confer enhanced tolerance to ethanol. The invention also provides related expression vectors, genetically engineered microorganisms having enhanced tolerance to ethanol, as well as methods of making and using such genetically modified microorganisms for production of biofuels based on fermentation of biomass materials. |
FILED | Friday, May 20, 2011 |
APPL NO | 13/112641 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Organic compounds 536/23.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629325 | Morant |
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FUNDED BY |
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APPLICANT(S) | Marc Morant (Copenhagen, Denmark) |
ASSIGNEE(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes, Inc. (Davis, California) |
INVENTOR(S) | Marc Morant (Copenhagen, Denmark) |
ABSTRACT | The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
FILED | Tuesday, August 30, 2011 |
APPL NO | 13/818208 |
ART UNIT | 1638 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/284 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08631086 | Blocksome et al. |
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FUNDED BY |
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APPLICANT(S) | Michael A. Blocksome (Rochester, Minnesota); Dong Chen (Croton On Hudson, New York); Thomas Gooding (Rochester, Minnesota); Philip Heidelberger (Cortlandt Manor, New York); Jeff Parker (Rochester, Minnesota) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Michael A. Blocksome (Rochester, Minnesota); Dong Chen (Croton On Hudson, New York); Thomas Gooding (Rochester, Minnesota); Philip Heidelberger (Cortlandt Manor, New York); Jeff Parker (Rochester, Minnesota) |
ABSTRACT | Embodiments of the invention may be used to manage message queues in a parallel computing environment to prevent message queue deadlock. A direct memory access controller of a compute node may determine when a messaging queue is full. In response, the DMA may generate an interrupt. An interrupt handler may stop the DMA and swap all descriptors from the full messaging queue into a larger queue (or enlarge the original queue). The interrupt handler then restarts the DMA. Alternatively, the interrupt handler stops the DMA, allocates a memory block to hold queue data, and then moves descriptors from the full messaging queue into the allocated memory block. The interrupt handler then restarts the DMA. During a normal messaging advance cycle, a messaging manager attempts to inject the descriptors in the memory block into other messaging queues until the descriptors have all been processed. |
FILED | Tuesday, September 30, 2008 |
APPL NO | 12/241514 |
ART UNIT | 2451 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/212 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 08627658 | McBride et al. |
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FUNDED BY |
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APPLICANT(S) | Troy O. McBride (Norwich, Vermont); Benjamin R. Bollinger (Windsor, Vermont); Michael Izenson (Hanover, New Hampshire); Weibo Chen (Hanover, New Hampshire); Patrick Magari (Plainfield, New Hampshire); Benjamin Cameron (Hanover, New Hampshire); Robert Cook (West Lebanon, New Hampshire); Horst Richter (Norwich, Vermont) |
ASSIGNEE(S) | SustainX, Inc. (Seabrook, New Hampshire) |
INVENTOR(S) | Troy O. McBride (Norwich, Vermont); Benjamin R. Bollinger (Windsor, Vermont); Michael Izenson (Hanover, New Hampshire); Weibo Chen (Hanover, New Hampshire); Patrick Magari (Plainfield, New Hampshire); Benjamin Cameron (Hanover, New Hampshire); Robert Cook (West Lebanon, New Hampshire); Horst Richter (Norwich, Vermont) |
ABSTRACT | The invention relates to systems and methods for rapidly and isothermally expanding and compressing gas in energy storage and recovery systems that use open-air hydraulic-pneumatic cylinder assemblies, such as an accumulator and an intensifier in communication with a high-pressure gas storage reservoir on a gas-side of the circuits and a combination fluid motor/pump, coupled to a combination electric generator/motor on the fluid side of the circuits. The systems use heat transfer subsystems in communication with at least one of the cylinder assemblies or reservoir to thermally condition the gas being expanded or compressed. |
FILED | Monday, January 24, 2011 |
APPL NO | 13/012610 |
ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
CURRENT CPC | Power plants 060/511 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628599 | Earthman et al. |
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FUNDED BY |
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APPLICANT(S) | James C. Earthman (Irvine, California); Farghalli A. Mohamed (Huntington Beach, California); Rahul K. Mishra (Cockeysville, Maryland); Indranil Roy (Liberal, Kansas) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | James C. Earthman (Irvine, California); Farghalli A. Mohamed (Huntington Beach, California); Rahul K. Mishra (Cockeysville, Maryland); Indranil Roy (Liberal, Kansas) |
ABSTRACT | Thermal stability of cryomilled Al+1% diamantane was investigated in the temperature range of 423 to 773K. Diamantane is a nanosized hydrocarbon molecule with a 14 carbon atom diamond cubic framework that is terminated by hydrogen atoms. Following the cryomilling of the Al powders and diamantane cages, the average grain size characterized using transmission electron microscopy (TEM) and X-ray diffraction (XRD). The as-cryomilled grain sized was found to be of the order of 22 nm, essentially the same as that for Al cryomilled without diamantane. To determine thermal stability, the powders were sealed in glass tubes in an Ar atmosphere to avoid oxidation and contamination and annealed at different temperatures between 423 and 773K for different holding times. Following these treatments, the grain size of cryomilled Al+1% diamantane was consistently less than that for cryomilled Al by about a factor of two. Preliminary investigations indicate that the grain growth exponent n decreased with increasing temperature, reaching a value of approximately 35 at 423 K. Such a high value of n suggests the operation of strong pinning forces on boundaries during annealing treatment. The thermal stability data were found to be consistent with Burke's model based on drag forces exerted by dispersion particles. |
FILED | Thursday, September 04, 2008 |
APPL NO | 12/204763 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/252 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628727 | Van Duyne et al. |
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FUNDED BY |
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APPLICANT(S) | Richard P. Van Duyne (Wilmette, Illinois); Xiaoyu Zhang (Urbana, Illinois); Jing Zhao (Evanston, Illinois); Alyson V. Whitney (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); George C. Schatz (Evanston, Illinois); Peter C. Stair (Northbrook, Illinois); Shengli Zou (Oviedo, Florida); Matthew Young (Allen, Michigan); Olga Lyandres (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Richard P. Van Duyne (Wilmette, Illinois); Xiaoyu Zhang (Urbana, Illinois); Jing Zhao (Evanston, Illinois); Alyson V. Whitney (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); George C. Schatz (Evanston, Illinois); Peter C. Stair (Northbrook, Illinois); Shengli Zou (Oviedo, Florida); Matthew Young (Allen, Michigan); Olga Lyandres (Chicago, Illinois) |
ABSTRACT | The present invention relates to compositions, devices and methods for detecting microorganisms (e.g., anthrax). In particular, the present invention provides portable, surface-enhanced Raman biosensors, and associated substrates, and methods of using the same, for use in rapidly detecting and identifying microorganisms (e.g., anthrax). |
FILED | Tuesday, August 28, 2007 |
APPL NO | 11/846352 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/402 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628753 | Murthy et al. |
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FUNDED BY |
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APPLICANT(S) | Niren Murthy (Atlanta, Georgia); W. Robert Taylor (Stone Mountain, Georgia); Kousik Kundu (Atlanta, Georgia); Sarah F. Knight (Atlanta, Georgia); Sungmun Lee (Dunwoody, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Niren Murthy (Atlanta, Georgia); W. Robert Taylor (Stone Mountain, Georgia); Kousik Kundu (Atlanta, Georgia); Sarah F. Knight (Atlanta, Georgia); Sungmun Lee (Dunwoody, Georgia) |
ABSTRACT | Reduced dyes, such as hydrocyanines, deuterocyanines, and/or other deuterated dyes capable of detecting one or more reactive oxygen species are described herein. The reduced dyes exhibit little or no fluorescence due to the disrupted π conjugation. However, upon reaction with ROS, the reduced dyes are oxidized, regenerating the extended π conjugation and causing a substantial increase in fluorescence intensity. In many case, the oxidized dye is generally membrane impermeable. However, upon reduction, many of the reduced dyes are membrane permeable. Thus, reduced dyes can accumulate in cells and/or tissue to amplify the signal. Once inside the cell or tissue, the reduced dye is reoxidized upon reaction with ROS, and the oxidized dye again becomes membrane impermeable, trapping the dye within the cell. The reduced dyes can be used to image ROS, such as hydroxide radical and superoxide, in serum, cell cultures, tissue explants, and in vivo. |
FILED | Tuesday, September 28, 2010 |
APPL NO | 12/892379 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628977 | Adamec et al. |
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FUNDED BY |
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APPLICANT(S) | Jiri Adamec (West Lafayette, Indiana); Wen-Chu Yang (West Lafayette, Indiana); Fred E. Regnier (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Jiri Adamec (West Lafayette, Indiana); Wen-Chu Yang (West Lafayette, Indiana); Fred E. Regnier (West Lafayette, Indiana) |
ABSTRACT | Reagents and methods are provided that permit simultaneous analysis of multiple diverse small molecule analytes present in a complex mixture. Samples are labeled with chemically identical but isotopically distinct forms of the labeling reagent, and analyzed using mass spectrometry. A single reagent simultaneously derivatizes multiple small molecule analytes having different reactive functional groups. |
FILED | Friday, May 01, 2009 |
APPL NO | 12/990560 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629251 | Benning et al. |
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FUNDED BY |
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APPLICANT(S) | Christoph Benning (East Lansing, Michigan); Zhen Wang (East Lansing, Michigan) |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Christoph Benning (East Lansing, Michigan); Zhen Wang (East Lansing, Michigan) |
ABSTRACT | The present invention is related to the field of phospholipid detection. In particular, certain embodiments provide the detection of phosphatidic acid. For example, certain proteins are capable of binding phosphatidic acid and can be used as a diagnostic and/or research tool to identify and quantitate phosphatidic acid. Phosphatidic acid may be in or from cells and tissues isolated from plants, animals and humans. For example, a trigalactosyldiacylglycerol-2 (TGD2) protein may be fused with a fluorescent probe to monitor and measure phosphatidic acid in vitro as well as in vivo. In other embodiments, a trigalactosyldiacylglycerol-4 (TGD4) protein may be fused with a fluorescent probe to monitor and measure phosphatidic acid in vitro as well as in vivo. In additional embodiments, a fragment comprising either a truncated TGD2 or TGD4 phosphatidic acid binding region protein may be used to monitor or measure phosphatidic acid. |
FILED | Friday, January 13, 2012 |
APPL NO | 13/350287 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/395 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629312 | Kraus |
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FUNDED BY |
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APPLICANT(S) | George A. Kraus (Ames, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | George A. Kraus (Ames, Iowa) |
ABSTRACT | The present invention provides a method to produce olefins by the decarboxylation of organic carboxylic acids in the presence of an organopalladium catalyst. |
FILED | Wednesday, March 16, 2011 |
APPL NO | 13/639209 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry of hydrocarbon compounds 585/638 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629329 | Amasino et al. |
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FUNDED BY |
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APPLICANT(S) | Richard M. Amasino (Madison, Wisconsin); Scott Woody (Windsor, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Richard M. Amasino (Madison, Wisconsin); Scott Woody (Windsor, Wisconsin) |
ABSTRACT | The invention provides Brassica rapa plants and seeds thereof that are self-compatible, rapid-cycling and lack inbreeding depression. For instance, the invention provides plants and seeds of the Brassica rapa line designated B3. The invention thus relates to plants, seeds and tissue cultures of Brassica rapa plants that are self-compatible, rapid-cycling and lack inbreeding depression, such as Brassica rapa line B3, and methods to produce and propagate said plants by crossing such a Brassica rapa plant with itself, or another Brassica rapa plant. The invention further relates to seeds and plants produced by such crossing. Educational materials, such as a kit comprising said Brassica rapa plants are also provided by the invention. |
FILED | Monday, May 17, 2010 |
APPL NO | 12/781705 |
ART UNIT | 1638 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/306 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630308 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Xiaodong Wang (New York, New York); Alberto Lopez Toledo (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Xiaodong Wang (New York, New York); Alberto Lopez Toledo (New York, New York) |
ABSTRACT | Methods and apparatuses for detecting deviations from legitimate operation on a wireless network. The method includes detecting a sequence of observable events related to operation of an entity in the wireless network, and determining from the detected sequence of observable events for a particular entity in the wireless network what number of idle slots occurred between two consecutive observable events to provide a first output. The method further includes obtaining a second output corresponding to the number of idle slots between two consecutive observable events for legitimate operation of any entity in the wireless network using the network transmission protocol, and comparing a function of the first output with a function of the second output to determine whether or not the particular entity is deviating from legitimate operation of the network transmission protocol. |
FILED | Thursday, April 26, 2007 |
APPL NO | 11/796499 |
ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Multiplex communications 370/458 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630519 | Sorin et al. |
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FUNDED BY |
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APPLICANT(S) | Fabien Sorin (Paris, France); Guillaume Lestoquoy (Cambridge, Massachusetts); Sylvain Danto (Clemson, Massachusetts); Yoel Fink (Brookline, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Fabien Sorin (Paris, France); Guillaume Lestoquoy (Cambridge, Massachusetts); Sylvain Danto (Clemson, Massachusetts); Yoel Fink (Brookline, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts) |
ABSTRACT | Photodetecting fiber. The fiber detects and localizes an incident optical beam. A semiconducting core is in intimate contact with a material forming a resistive channel that breaks axial symmetry. The resistive channel has a resistivity between that of metals and the semiconducting core, enabling the imposition of non-uniform, convex electric potential distributions along the fiber axis allowing photo-current measurements along the fiber. |
FILED | Wednesday, October 05, 2011 |
APPL NO | 13/253200 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Optical waveguides 385/101 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630966 | Gage et al. |
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FUNDED BY |
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APPLICANT(S) | Fred H. Gage (La Jolla, California); James Bradley Aimone (San Diego, California); Janet Wiles (St. Lucia, Australia) |
ASSIGNEE(S) | Salk Institute for Biological Studies (LaJolla, California) |
INVENTOR(S) | Fred H. Gage (La Jolla, California); James Bradley Aimone (San Diego, California); Janet Wiles (St. Lucia, Australia) |
ABSTRACT | An apparatus, article and method containing an artificial neural network that, after training, produces new trainable nodes such that input data representative of a first event and input data representative of a second event both activate a subset of the new trainable nodes. The artificial neural network can generate an output that is influenced by the input data of both events. In various embodiments, the new trainable nodes are sequentially produced and show decreasing trainability over time such that, at a particular point in time, newer produced nodes are more trainable than earlier produced nodes. The artificial neural network can be included in various embodiments of methods, apparatus and articles for use in predicting or profiling events. |
FILED | Wednesday, January 27, 2010 |
APPL NO | 12/657748 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/082 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630975 | Guo et al. |
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FUNDED BY |
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APPLICANT(S) | Zhen Guo (Warrington, Pennsylvania); Mark Zhang (Vernon, Connecticut) |
ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
INVENTOR(S) | Zhen Guo (Warrington, Pennsylvania); Mark Zhang (Vernon, Connecticut) |
ABSTRACT | In a corpus of scientific articles such as a digital library, documents are connected by citations and one document plays two different roles in the corpus: document itself and a citation of other documents. A Bernoulli Process Topic (BPT) model is provided which models the corpus at two levels: document level and citation level. In the BPT model, each document has two different representations in the latent topic space associated with its roles. Moreover, the multi-level hierarchical structure of the citation network is captured by a generative process involving a Bernoulli process. The distribution parameters of the BPT model are estimated by a variational approximation approach. |
FILED | Friday, December 02, 2011 |
APPL NO | 13/310098 |
ART UNIT | 2163 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/608 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08631035 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Chen Li (Irvine, California); Shengyue Ji (Irvine, California); Guoliang Li (Beijing, China PRC); Jiannan Wang (Beijing, China PRC); Jianhua Feng (Beijing, China PRC) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Chen Li (Irvine, California); Shengyue Ji (Irvine, California); Guoliang Li (Beijing, China PRC); Jiannan Wang (Beijing, China PRC); Jianhua Feng (Beijing, China PRC) |
ABSTRACT | A method to support efficient, interactive, and fuzzy search on text data includes an interactive, fuzzy search on structured data used in applications such as query relaxation, autocomplete, and spell checking, where inconsistencies and errors exist in user queries as well as data. It utilizes techniques to efficiently and interactively answer fuzzy queries on structured data to allow users to efficiently search for information interactively, and they can find records and documents even if these records and documents are slightly different from the user keywords. |
FILED | Monday, November 14, 2011 |
APPL NO | 13/295767 |
ART UNIT | 2167 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/780 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08631044 | Jebara et al. |
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FUNDED BY |
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APPLICANT(S) | Tony Jebara (New York, New York); Bert Huang (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Tony Jebara (New York, New York); Bert Huang (New York, New York) |
ABSTRACT | A method, system, computer program product and computer readable media for matching using degree distribution information are disclosed. An embodiment of the method can include performing b-matching on a graph data structure expanded using degree distribution information in order to identify neighbors of a selected input node. The b-matching can be performed using belief propagation. The belief propagation method is adapted to use a compressed message update rule and to be suitable for use with distributed processing systems. An embodiment can also include enhancing a matching result by applying degree distribution information to a first matching result to generate a second matching result. Embodiments for online advertisement/search term matching, product recommendation, dating service and social network matching, auction buyer/seller matching and resource allocation, among other, are disclosed. |
FILED | Friday, December 11, 2009 |
APPL NO | 13/133932 |
ART UNIT | 2164 — Data Bases & File Management |
CURRENT CPC | Data processing: Database and file management or data structures 77/798 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08631290 | Zandian et al. |
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FUNDED BY |
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APPLICANT(S) | Bardia Zandian (Los Angeles, California); Murali Annavaram (Los Angeles, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Bardia Zandian (Los Angeles, California); Murali Annavaram (Los Angeles, California) |
ABSTRACT | An automated guardband compensation system automatically compensates for degradation in the guardband of a clocked data processing circuit while that circuit is connected within a data processing system. A control circuit automatically and repeatedly requests: a switching circuit to switch a critical path within the clocked data processing circuit out of a data processing pathway within the data processing system while the clocked data processing circuit is connected within the data processing system; a guardband test circuit to test the guardband of the critical path while the critical path is switched out of the data processing pathway; a guardband compensation circuit to increase the guardband when the results of the test indicate a material degradation in the guardband; and a switching circuit to switch the critical path back into the data processing pathway after the test. |
FILED | Thursday, December 15, 2011 |
APPL NO | 13/327561 |
ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/731 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08631484 | Stavrou et al. |
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FUNDED BY |
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APPLICANT(S) | Angelos Stavrou (New York, New York); Angelos D. Keromytis (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Angelos Stavrou (New York, New York); Angelos D. Keromytis (New York, New York) |
ABSTRACT | Systems and methods for inhibiting attacks with a network are provided. In some embodiments, methods for inhibiting attacks by forwarding packets through a plurality of intermediate nodes when being transmitted from a source node to a destination node are provided, the methods comprising: receiving a packet at one of the plurality of intermediate nodes; determining at the selected intermediate node whether the packet has been sent to the correct one of the plurality of intermediate nodes based on a pseudo random function; and forwarding the packet to the destination node, based on the determining. In some embodiments an intermediate node is selected based on a pseudo random function. In some embodiments, systems and methods for establishing access to a multi-path network are provided. |
FILED | Friday, March 14, 2008 |
APPL NO | 12/048533 |
ART UNIT | 2435 — Cryptography and Security |
CURRENT CPC | Information security 726/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 08627724 | Papadopoulos et al. |
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FUNDED BY |
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APPLICANT(S) | George Papadopoulos (Nesconset, New York); Nicholas Tiliakos (Huntington Station, New York); Gabriel Benel (New York, New York); Clint Thomson (Smithfield, Utah) |
ASSIGNEE(S) | Alliant Techsystems Inc. (Minneapolis, Minnesota) |
INVENTOR(S) | George Papadopoulos (Nesconset, New York); Nicholas Tiliakos (Huntington Station, New York); Gabriel Benel (New York, New York); Clint Thomson (Smithfield, Utah) |
ABSTRACT | A non-intrusive sensor for in-situ measurement of recession rate of heat shield ablatives. An ultrasonic wave source is carried in the housing. A microphone is also carried in the housing, for collecting the reflected ultrasonic waves from an interface surface of the ablative material. A time phasing control circuit is also included for time-phasing the ultrasonic wave source so that the waves reflected from the interface surface of the ablative material focus on the microphone, to maximize the acoustic pressure detected by the microphone and to mitigate acoustic velocity variation effects through the material through a de-coupling process that involves a software algorithm. A software circuit for computing the location off of which the ultrasonic waves scattered to focus back at the microphone is also included, so that the recession rate of the heat shield ablative may be monitored in real-time through the scan-focus approach. |
FILED | Thursday, September 01, 2011 |
APPL NO | 13/224214 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/598 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628238 | Fesmire et al. |
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FUNDED BY |
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APPLICANT(S) | James E. Fesmire (Titusville, Florida); Adam G. Dokos (Titusville, Florida) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | James E. Fesmire (Titusville, Florida); Adam G. Dokos (Titusville, Florida) |
ABSTRACT | A multi-purpose, cylindrical thermal insulation test apparatus is used for testing insulation materials and systems of materials using a liquid boil-off calorimeter system for absolute measurement of the effective thermal conductivity (k-value) and heat flux of a specimen material at a fixed environmental condition (cold-side temperature, warm-side temperature, vacuum pressure level, and residual gas composition). The apparatus includes an inner vessel for receiving a liquid with a normal boiling point below ambient temperature, such as liquid nitrogen, enclosed within a vacuum chamber. A cold mass assembly, including the upper and lower guard chambers and a middle test vessel, is suspended from a lid of the vacuum canister. Each of the three chambers is filled and vented through a single feedthrough. All fluid and instrumentation feedthroughs are mounted and suspended from a top domed lid to allow easy removal of the cold mass. A lift mechanism allows manipulation of the cold mass assembly and insulation test article. |
FILED | Friday, June 11, 2010 |
APPL NO | 12/813864 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Thermal measuring and testing 374/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628333 | Prinzel, III et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence J. Prinzel, III (Hampton, Virginia); Alan T. Pope (Poquoson, Virginia); Olafur S. Palsson (Chapel Hill, North Carolina); Marsha J. Turner (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Lawrence J. Prinzel, III (Hampton, Virginia); Alan T. Pope (Poquoson, Virginia); Olafur S. Palsson (Chapel Hill, North Carolina); Marsha J. Turner (Chapel Hill, North Carolina) |
ABSTRACT | The invention is an apparatus and method of biofeedback training for attaining a physiological state optimally consistent with the successful performance of a task, wherein the probability of successfully completing the task is made is inversely proportional to a physiological difference value, computed as the absolute value of the difference between at least one physiological signal optimally consistent with the successful performance of the task and at least one corresponding measured physiological signal of a trainee performing the task. The probability of successfully completing the task is made inversely proportional to the physiological difference value by making one or more measurable physical attributes of the environment in which the task is performed, and upon which completion of the task depends, vary in inverse proportion to the physiological difference value. |
FILED | Friday, May 13, 2005 |
APPL NO | 11/129756 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Education and demonstration 434/247 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628517 | Beebe et al. |
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FUNDED BY |
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APPLICANT(S) | David J. Beebe (Monona, Wisconsin); Michael J. MacDonald (Madison, Wisconsin); David T. Eddington (Madison, Wisconsin); Glennys A. Mensing (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Michael J. MacDonald (Madison, Wisconsin); David T. Eddington (Madison, Wisconsin); Glennys A. Mensing (Madison, Wisconsin) |
ABSTRACT | A microfluidic device is provided for delivering a drug to an individual. The microfluidic device includes a body that defines a reservoir for receiving the drug therein. A valve interconnects the reservoir to an output needle that is insertable into the skin of an individual. A pressure source urges the drug from the reservoir toward the needle. The valve is movable between a closed position preventing the flow of the drug from the reservoir to the output needle and an open position allowing for the flow of the drug from the reservoir to the output needle in response to a predetermined condition in the physiological fluids of the individual. |
FILED | Wednesday, June 23, 2010 |
APPL NO | 12/821743 |
ART UNIT | 3767 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Surgery 64/890.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629262 | Bailey et al. |
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FUNDED BY |
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APPLICANT(S) | Susan M. Bailey (Severance, Colorado); F. Andrew Ray (Fort Collins, Colorado); Edwin H. Goodwin (Los Alamos, New Mexico); Joel S. Bedford (Fort Collins, Colorado); Michael N. Cornforth (Houston, Texas) |
ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Susan M. Bailey (Severance, Colorado); F. Andrew Ray (Fort Collins, Colorado); Edwin H. Goodwin (Los Alamos, New Mexico); Joel S. Bedford (Fort Collins, Colorado); Michael N. Cornforth (Houston, Texas) |
ABSTRACT | A method and a kit for the identification of chromosomal inversions are described. Single-stranded sister chromatids are generated, for example by CO-FISH. A plurality of non-repetitive, labeled probes of relatively small size are hybridized to portions of only one of a pair of single-stranded sister chromatids. If no inversion exists, all of the probes will hybridize to a first chromatid. If an inversion has occurred, these marker probes will be detected on the sister chromatid at the same location as the inversion on the first chromatid. |
FILED | Monday, November 14, 2011 |
APPL NO | 13/295585 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/24.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08630830 | DiStefano, III et al. |
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FUNDED BY |
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APPLICANT(S) | Frank James DiStefano, III (Houston, Texas); Craig A. Wobick (Seabrook, Texas); Kirt Auldwin Chapman (Webster, Texas); Peter L. McCloud (Shoreacres, Texas) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Frank James DiStefano, III (Houston, Texas); Craig A. Wobick (Seabrook, Texas); Kirt Auldwin Chapman (Webster, Texas); Peter L. McCloud (Shoreacres, Texas) |
ABSTRACT | A thermal fluid system modeler including a plurality of individual components. A solution vector is configured and ordered as a function of one or more inlet dependencies of the plurality of individual components. A fluid flow simulator simulates thermal energy being communicated with the flowing fluid and between first and second components of the plurality of individual components. The simulation extends from an initial time to a later time step and bounds heat transfer to be substantially between the flowing fluid, walls of tubes formed in each of the individual components of the plurality, and between adjacent tubes. Component parameters of the solution vector are updated with simulation results for each of the plurality of individual components of the simulation. |
FILED | Monday, October 11, 2010 |
APPL NO | 12/901850 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/9 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 08628764 | Slininger et al. |
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FUNDED BY |
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APPLICANT(S) | Patricia J. Slininger (Metamora, Illinois); David A. Schisler (Morton, Illinois) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Patricia J. Slininger (Metamora, Illinois); David A. Schisler (Morton, Illinois) |
ABSTRACT | Bacterial compositions effective for inhibiting fungal diseases of potatoes and/or potato sprouting are produced by co-culture of two or more of Pseudomonas fluorescens (NRRL B-21133), Pseudomonas fluorescens biovar (NRRL B-21053), Pseudomonas fluorescens (NRRL B-21102) and Enterobacter cloacae (NRRL B-21050). Compositions produced by co-culture of these bacteria together in the same culture medium are significantly more effective for inhibiting fungi-induced diseases of potatoes and/or inhibiting sprouting of potatoes, than blends or mixtures of the same bacteria cultured separately. |
FILED | Wednesday, August 29, 2012 |
APPL NO | 13/597834 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629249 | Oliver et al. |
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FUNDED BY |
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APPLICANT(S) | Stephen P. Oliver (Maryville, Tennessee); Raul A. Almeida (Knoxville, Texas); Douglas A. Luther (Louisville, Tennessee); Hee-Myung Park (Suwon-si, South Korea) |
ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Stephen P. Oliver (Maryville, Tennessee); Raul A. Almeida (Knoxville, Texas); Douglas A. Luther (Louisville, Tennessee); Hee-Myung Park (Suwon-si, South Korea) |
ABSTRACT | A polypeptide, designated as “Streptococcus uberis Adhesion Molecule” (SUAM), and fragments of SUAM, prevent internalization and adherence of Streptococcus uberis and other streptococcal pathogens to cells. The SUAM polypeptide and fragments may be used diagnostically and therapeutically. Nucleic acid sequences encoding the SUAM polypeptide and fragments are included in the invention. |
FILED | Monday, June 07, 2010 |
APPL NO | 12/802422 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.900 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629681 | Trabelsi et al. |
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FUNDED BY |
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APPLICANT(S) | Samir Trabelsi (Athens, Georgia); Stuart O. Nelson (Athens, Georgia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Samir Trabelsi (Athens, Georgia); Stuart O. Nelson (Athens, Georgia) |
ABSTRACT | A microwave sensor and algorithm for instantaneous and nondestructive determination of bulk density and moisture content in granular or particulate materials at a single microwave frequency, especially agricultural commodities, which uses an inexpensive microwave circuit for determining the real and imaginary parts of relative complex permittivity using an algorithm for phase correction. |
FILED | Tuesday, May 18, 2010 |
APPL NO | 12/782079 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/639 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 08628747 | Zachariah et al. |
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FUNDED BY |
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APPLICANT(S) | Michael R. Zachariah (Potomac, Maryland); Soo H. Kim (Miryang-si, South Korea) |
ASSIGNEE(S) | University of Maryland College Park (College Park, Maryland) |
INVENTOR(S) | Michael R. Zachariah (Potomac, Maryland); Soo H. Kim (Miryang-si, South Korea) |
ABSTRACT | Carbon nanotube structures are formed by providing metal composite particles including a catalyst metal and a non-catalyst metal, where the catalyst metal catalyzes the decomposition of a hydrocarbon compound and the formation of carbon nanotube structures on surfaces of the particles. The metal composite particles are combined with the hydrocarbon compound in a heated environment so as to form carbon nanotube structures on the surfaces of the metal composite particles. The metal composite particles can be include iron and aluminum at varying amounts. The carbon nanotubes formed on the metal particles can remain on the metal particles or, alternatively, be removed from the metal particles for use in different applications. |
FILED | Friday, December 21, 2007 |
APPL NO | 11/962130 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/447.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629427 | Banerjee et al. |
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FUNDED BY |
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APPLICANT(S) | Sanjay K. Banerjee (Austin, Texas); Leonard Franklin Register, II (Round Rock, Texas); Allan MacDonald (Austin, Texas); Bhagawan R. Sahu (Austin, Texas); Priyamvada Jadaun (Austin, Texas); Jiwon Chang (Austin, Texas) |
ASSIGNEE(S) | Texas A and M University (College Station, Texas) |
INVENTOR(S) | Sanjay K. Banerjee (Austin, Texas); Leonard Franklin Register, II (Round Rock, Texas); Allan MacDonald (Austin, Texas); Bhagawan R. Sahu (Austin, Texas); Priyamvada Jadaun (Austin, Texas); Jiwon Chang (Austin, Texas) |
ABSTRACT | A Topological INsulator-based field-effect transistor (TINFET) is disclosed. The TINFET includes a first and second gate dielectric layers separated by a topological insulator (TI) layer. A first gate contact is connected to the first gate dielectric layer on the surface that is opposite the TI layer. A second gate contact may be connected to the second gate dielectric layer on the surface that is opposite the TI layer. A first TI surface contact is connected to one surface of the TI layer, and a second TI surface contact is connected to the second surface of the TI layer. |
FILED | Friday, April 29, 2011 |
APPL NO | 13/097405 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/20 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08629783 | Mitchell et al. |
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FUNDED BY |
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APPLICANT(S) | David J. Mitchell (Oviedo, Florida); Anand A. Kulkarni (Oviedo, Florida); Ramesh Subramanian (Oviedo, Florida); Edward R. Roesch (Orlando, Florida); Rod Waits (Sunnyvale, California); Roberto Schupbach (Fayetteville, Arkansas); John R. Fraley (Fayetteville, Arkansas); Alexander B. Lostetter (Fayetteville, Arkansas); Brice McPherson (Fayetteville, Arkansas); Bryon Western (West Fork, Arkansas) |
ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida); Arkansas Power Electronics International, Inc. (Fayetteville, Arkansas) |
INVENTOR(S) | David J. Mitchell (Oviedo, Florida); Anand A. Kulkarni (Oviedo, Florida); Ramesh Subramanian (Oviedo, Florida); Edward R. Roesch (Orlando, Florida); Rod Waits (Sunnyvale, California); Roberto Schupbach (Fayetteville, Arkansas); John R. Fraley (Fayetteville, Arkansas); Alexander B. Lostetter (Fayetteville, Arkansas); Brice McPherson (Fayetteville, Arkansas); Bryon Western (West Fork, Arkansas) |
ABSTRACT | In a telemetry system for use in an engine, a circuit structure (34) affixed to a moving part (20) of the engine is disposed for amplifying information sensed about a condition of the part and transmitting the sensed information to a receiver external to the engine. The circuit structure is adapted for the high temperature environment of the engine and includes a differential amplifier (102, 111) having an input for receiving a signal from a sensor (101, 110) disposed on the part. A voltage controlled oscillator (104, 115) with an input coupled to the output of the amplifier produces an oscillatory signal having a frequency representative of the sensed condition. A buffer (105, 116) with an input coupled to the output of the oscillator buffers the oscillatory signal, which is then coupled to an antenna (26) for transmitting the information to the receiver. |
FILED | Tuesday, June 19, 2012 |
APPL NO | 13/526933 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Electrical 340/870.70 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
US 08631063 | Helal et al. |
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FUNDED BY |
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APPLICANT(S) | Abdelsalam Helal (Gainesville, Florida); Jeffrey Craig King (Gainesville, Florida); Raja Bose (Gainesville, Florida); Steven Lee Pickles (Wellington, Florida); James A. Russo (Clermont, Florida); Steve Vander Ploeg (Hillsboro, Oregon); Hicham Mahmoud El Zabadani (Dubai, Arab Emirates); Ahmad Hassan El Kouche (Kingston, Canada) |
ASSIGNEE(S) | |
INVENTOR(S) | Abdelsalam Helal (Gainesville, Florida); Jeffrey Craig King (Gainesville, Florida); Raja Bose (Gainesville, Florida); Steven Lee Pickles (Wellington, Florida); James A. Russo (Clermont, Florida); Steve Vander Ploeg (Hillsboro, Oregon); Hicham Mahmoud El Zabadani (Dubai, Arab Emirates); Ahmad Hassan El Kouche (Kingston, Canada) |
ABSTRACT | A system includes a hardware platform, at least one driver, a plurality of devices connected to the hardware platform, a middleware interface, and a plurality of software services. Each of the plurality of devices is selected from the group consisting of sensors and actuators. The plurality of software services is generated by the at least one driver, wherein a software service associates with a device, and wherein each of the software services complies with the middleware interface. A method for interfacing a plurality of devices to a hardware platform includes communicably connecting each of the plurality of devices to the hardware platform, converting each of the plurality of devices into a programmable software service using a driver, and programming each of the software services to comply with a middleware interface. |
FILED | Friday, January 07, 2011 |
APPL NO | 12/986301 |
ART UNIT | 2448 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/201 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 08629098 | Fahmy et al. |
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FUNDED BY |
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APPLICANT(S) | Tarek Fahmy (New Haven, Connecticut); Erin Steenblock (Janesville, Wisconsin) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Tarek Fahmy (New Haven, Connecticut); Erin Steenblock (Janesville, Wisconsin) |
ABSTRACT | Modular aAPCs and methods of their manufacture and use are provided. The modular aAPCs are constructed from polymeric microparticles. The aAPCs include encapsulated cytokines and coupling agents which modularly couple functional elements including T cell receptor activators, co-stimulatory molecules and adhesion molecules to the particle. The ability of these aAPCs to release cytokines in a controlled manner, coupled with their modular nature and ease of ligand attachment, results in an ideal, tunable APC capable of stimulating and expanding primary T cells. |
FILED | Wednesday, January 14, 2009 |
APPL NO | 12/812304 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 08628781 | Sanders |
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FUNDED BY |
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APPLICANT(S) | Paul W. Sanders (Birmingham, Alabama) |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); The United States of America, as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Paul W. Sanders (Birmingham, Alabama) |
ABSTRACT | Provided herein are polypeptides comprising or consisting essentially of a QSYDNTLSGSYVF (SEQ ID NO:1) or LSADSSGSYLYVF (SEQ ID NO:2) amino acid sequence. Also provided herein are methods of treating or preventing cast nephropathy in a subject. The methods comprise identifying a subject with or at risk of developing cast nephropathy and administering to the subject any of the polypeptides disclosed herein. |
FILED | Friday, April 01, 2011 |
APPL NO | 13/639002 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 08630627 | Davitz et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey Davitz (Danville, California); Sugato Basu (Redwood City, California); Jiye Yu (Menlo Park, California); David Gutelius (Menlo Park, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Jeffrey Davitz (Danville, California); Sugato Basu (Redwood City, California); Jiye Yu (Menlo Park, California); David Gutelius (Menlo Park, California) |
ABSTRACT | In one embodiment, the present invention is a method and apparatus for knowledge generation and deployment in a distributed network. In one embodiment, a method for processing messages in a social network includes receiving a new message from a first node in the network, the new message including a query, providing the first node with an answer to the query, if the answer is located in a repository, and initiating generation of the answer, if the answer is not located in the repository. |
FILED | Tuesday, February 06, 2007 |
APPL NO | 11/671943 |
ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Telecommunications 455/414.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 08628462 | Berka et al. |
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FUNDED BY |
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APPLICANT(S) | Chris Berka (Carlsbad, California); Djordje Popovic (Carlsbad, California); Gene Davis (Carlsbad, California); Matthew A. Yanagi (Carlsbad, California) |
ASSIGNEE(S) | Advanced Brain Monitoring, Inc. (Carlsbad, California) |
INVENTOR(S) | Chris Berka (Carlsbad, California); Djordje Popovic (Carlsbad, California); Gene Davis (Carlsbad, California); Matthew A. Yanagi (Carlsbad, California) |
ABSTRACT | Systems and methods for optimizing the sleep and post-sleep performance of individuals regardless of their environment and time available for sleep are provided. The systems and methods take into account factors that determine the effects of a sleep episode on dexterity, cognitive functions and the subjective feeling of fatigue after sleeping: duration and sleep architecture of the sleep episode, point on the circadian cycle at which the episode occurred, the amount of sleep debt accumulated prior to the episode and the subject's susceptibility to sleep deprivation. The systems and methods include monitoring of sleep architecture over a longer period of time, measurement of accumulated sleep debt and assessment and/or tailoring of the sleep architecture for each subsequent sleep episode, determining a desired sleep state in which the subject should be in, and generating sensory stimuli for guiding the subject to the desired sleep state. |
FILED | Tuesday, October 06, 2009 |
APPL NO | 12/574631 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Surgery 6/27 |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 08630466 | Hoeschen et al. |
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FUNDED BY |
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APPLICANT(S) | Christoph Hoeschen (Hebertshausen, Germany); Oleg Tischenko (München, Germany); Yuan Xu (Eugene, Oregon) |
ASSIGNEE(S) | State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon (Eugene, Oregon); Helmholtz Zentrum Munchen Deutsches Forschungszentrum fur Gesundheit und Umwelt (GmbH) (Neuherberg, Germany) |
INVENTOR(S) | Christoph Hoeschen (Hebertshausen, Germany); Oleg Tischenko (München, Germany); Yuan Xu (Eugene, Oregon) |
ABSTRACT | An image processing method for providing a digitized image as an approximation of an image function ƒ, wherein the digitized image comprises a plurality of pixels with a predetermined pixel size, comprises the steps of providing the image function ƒ from Radon data comprising a plurality of projection functions measured corresponding to a plurality of predetermined projection directions (v), and determining pixel values from the image function, the pixel values representing the digitized image to be obtained, wherein the pixel values are determined in dependence on at least two image function values within the pixel size of the respective pixel. Furthermore, an imaging method and an imaging device using the image processing method are described. |
FILED | Friday, February 08, 2008 |
APPL NO | 12/527188 |
ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Image analysis 382/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 08629365 | Avant et al. |
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FUNDED BY |
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APPLICANT(S) | Oscar Lee Avant (Silver Spring, Maryland); Margaret Boldt (Monrovia, legal representative, Maryland); Bruce A. Brandt (Gainesville, Virginia); Jay David Fadely (Palmetto, Florida); Michael Ray Little (Fairfax, Virginia); Simon Franklin Reidel (Rockville, Maryland) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Oscar Lee Avant (Silver Spring, Maryland); Ralph William Boldt, Jr. (Monrovia, Maryland); Margaret Boldt (Monrovia, legal representative, Maryland); Bruce A. Brandt (Gainesville, Virginia); Jay David Fadely (Palmetto, Florida); Michael Ray Little (Fairfax, Virginia); Simon Franklin Reidel (Rockville, Maryland) |
ABSTRACT | Apparatus and methods consistent with the present invention provide for identifying and processing mail using an identification code on a mailpiece as a redundant source of identification information in a mail sorting system. In one embodiment, this information is stored in a temporary database and used for the identification and processing of mail in a Remote Bar Code System (RBCS). In this embodiment, the identification code enables the automation of mail sorting and other processing tasks, reducing costs and delays in mail delivery services. In another embodiment, the identification and processing of mail occurs in and identification Code Sorting (ICS) system. In this embodiment, a long-term database allows for mail sorting and other processing tasks on a national or global level. |
FILED | Wednesday, June 20, 2012 |
APPL NO | 13/527628 |
ART UNIT | 3653 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Classifying, separating, and assorting solids 29/584 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 08627867 | Lahood et al. |
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FUNDED BY |
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APPLICANT(S) | John Lahood (North Andover, Massachusetts); Edward Hardy (Milford, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | John Lahood (North Andover, Massachusetts); Edward Hardy (Milford, New Hampshire) |
ABSTRACT | The system contains a lamination press. The first cavity is formed in a chassis. A film assembly is fitted within the chassis. A buffer mounts over the film assembly and within the chassis. A tool set is shaped to fit within the first cavity. The tool set and chassis are positioned within the lamination press to confer heat and pressure from the lamination press to the film assembly and chassis. |
FILED | Tuesday, April 21, 2009 |
APPL NO | 12/427317 |
ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/358 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08628146 | Baltazar-Lopez et al. |
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FUNDED BY |
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APPLICANT(S) | Martin E. Baltazar-Lopez (Auburn, Alabama); Steve R. Best (Montgomery, Alabama) |
ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
INVENTOR(S) | Martin E. Baltazar-Lopez (Auburn, Alabama); Steve R. Best (Montgomery, Alabama) |
ABSTRACT | A method, system and apparatus for plasma blasting comprises a solid object having a borehole, a blast probe comprising a high voltage electrode and a ground electrode separated by a dielectric separator, wherein the high voltage electrode and the dielectric separator constitute an adjustable probe tip, and an adjustment unit coupled to the adjustable probe tip, wherein the adjustment unit is configured to selectively extend or retract the adjustable probe tip relative to the ground electrode and a blasting media, wherein at least a portion of the high voltage electrode and the ground electrode are submerged in the blast media. The blasting media comprises a thixotropic or electro-rheological fluid. The adjustable tip permits fine-tuning of the blast. The property of instantaneous high viscosity of thixotropic and electro-rheological fluids is advantageously used to seal the cavity containing the blasting probe thereby increasing the blasting pressure making the whole system more efficient. |
FILED | Wednesday, March 17, 2010 |
APPL NO | 12/726038 |
ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Mining or in situ disintegration of hard material 299/14 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 14, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140114.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page