FedInvent™ Patents
Patent Details for Tuesday, April 01, 2014
This page was updated on Monday, March 27, 2023 at 03:58 AM GMT
Department of Health and Human Services (HHS)
| US 08684946 | Sims et al. |
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| FUNDED BY |
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| APPLICANT(S) | Janene Sims (Trussville, Alabama); Robert N. Kleinstein (Birmingham, Alabama) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Janene Sims (Trussville, Alabama); Robert N. Kleinstein (Birmingham, Alabama) |
| ABSTRACT | The present disclosure describes a psychophysical test to assess the cone photoreceptor pathway by determining the sensitivity of the cone photoreceptors. The test may be used to determine of a subject is suffering from, or is likely to suffer from, a disease state involving the fovea, parafovea, macula, neurological pathways used by these area to communicate with the visual processing centers in the brain and cone photoreceptors and/or ganglion cells. The present disclosure also describes an apparatus for such testing purposes. Using the novel cone photoreceptor sensitivity test and apparatus, the present disclosure shows that cone photoreceptor sensitivity in subjects with primary open angle glaucoma was decreased as compared to a control group (p=0.04). This cone photoreceptor sensitivity test is shown to have excellent repeatability, can be administered in a short time, does not require extensive subject instruction and meets other limitations required for application in a clinical setting. |
| FILED | Tuesday, December 19, 2006 |
| APPL NO | 11/641169 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/558 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685216 | De Bruyker et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dirk De Bruyker (Palo Alto, California); Michael I. Recht (Mountain View, California); Jürgen H. Daniel (Mountain View, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Dirk De Bruyker (Palo Alto, California); Michael I. Recht (Mountain View, California); Jürgen H. Daniel (Mountain View, California) |
| ABSTRACT | An apparatus for merging and mixing two droplets using electrostatic forces includes a substrate on which are disposed a first originating electrode, a center electrode, and a second originating electrode. The electrodes are disposed such that a first gap is formed between the first originating electrode and the center electrode and a second gap is formed between the second originating electrode and the center electrode. A dielectric material surrounds the electrodes on the substrate. A first droplet is deposited asymmetrically across the first gap, and a second droplet is deposited asymmetrically across the second gap. Voltage potentials are placed across the first gap and second gap, respectively, whereby each droplet is moved toward the other such that they collide together, causing the droplets to merge and mix, and causing oscillations within the collided droplet. |
| FILED | Tuesday, December 21, 2004 |
| APPL NO | 11/018757 |
| ART UNIT | 1758 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/547 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685344 | Sudarsan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arjun Sudarsan (Cary, North Carolina); Michael G. Pollack (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina); Vijay Srinivasan (Durham, North Carolina) |
| ASSIGNEE(S) | Advanced Liquid Logic, Inc. (Morrisville, North Carolina) |
| INVENTOR(S) | Arjun Sudarsan (Cary, North Carolina); Michael G. Pollack (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina); Vijay Srinivasan (Durham, North Carolina) |
| ABSTRACT | The present invention relates to surface assisted fluid loading and droplet dispensing on a droplet micro actuator. A droplet actuator is provided and includes one or more electrodes configured for conducting one or more droplet operations on a droplet operations surface of the substrate. The droplet actuator further includes a wettable surface defining a path from a fluid reservoir into a locus which is sufficiently near to one or more of the electrodes that activation of the one or more electrodes results in a droplet operation. Methods and systems are also provided. |
| FILED | Tuesday, January 22, 2008 |
| APPL NO | 12/523776 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/504 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685372 | Tsien et al. |
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| FUNDED BY |
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| APPLICANT(S) | Roger Y. Tsien (La Jolla, California); Quyen T. Nguyen (Del Mar, California); Michael Whitney (San Diego, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Y. Tsien (La Jolla, California); Quyen T. Nguyen (Del Mar, California); Michael Whitney (San Diego, California) |
| ABSTRACT | The present invention provides methods for guiding preservation of neurons or nerves during surgery by administering a fluorescently-labeled peptide or aptamer that specifically binds to the neurons or nerves. The invention further provides targeting molecules of fluorescently-labeled peptides or aptamers that specifically bind to neurons or nerves and for compositions thereof. |
| FILED | Thursday, April 15, 2010 |
| APPL NO | 13/264512 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685384 | Podack et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eckhard R. Podack (Coconut Grove, Florida); Julie Spielman (Miami, Florida); Koichi Yamazaki (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Eckhard R. Podack (Coconut Grove, Florida); Julie Spielman (Miami, Florida); Koichi Yamazaki (Miami, Florida) |
| ABSTRACT | The present invention relates to methods for purifying immunogenic, prophylactically and therapeutically effective complexes of modified heat shock proteins noncovalently associated with antigenic peptides of cancer or infected cells. The claimed methods comprise the constructing of a nucleotide sequence encoding a secretable modified heat shock protein, expressing the sequence in an appropriate host cell, recovering the immunogenic complexes from the cell culture and the cells, and purifying the immunogenic complexes by affinity chromatography. Large amounts of such immunogenic complexes can be obtained by large-scale culturing of host cells containing the genetic sequence. The complexes can be used as a vaccine to elicit specific immune responses against cancer or infected cells, and to treat or prevent cancer or infectious diseases. |
| FILED | Tuesday, July 24, 2007 |
| APPL NO | 11/878460 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685385 | Chancellor et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael B. Chancellor (Pittsburg, Pennsylvania); Johnny Huard (Pittsburgh, Pennsylvania); Christopher C. Capelli (Kenosha, Wisconsin); Zhuqing Qu (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Univeristy of Pittsburgh of the Commonwelath System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Michael B. Chancellor (Pittsburg, Pennsylvania); Johnny Huard (Pittsburgh, Pennsylvania); Christopher C. Capelli (Kenosha, Wisconsin); Zhuqing Qu (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for dermatological conditions, gastroesophageal reflux, vesico-ureteral reflux, urinary incontinence, fecal incontinence, heart failure, and myocardial infarction. |
| FILED | Wednesday, March 02, 2011 |
| APPL NO | 13/038827 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685392 | Helmerhorst et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eva J. Helmerhorst (Chestnut Hill, Massachusetts); Frank G. Oppenheim (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Eva J. Helmerhorst (Chestnut Hill, Massachusetts); Frank G. Oppenheim (Chestnut Hill, Massachusetts) |
| ABSTRACT | The invention relates to glutamine endopeptidase enzymes from Rothia spp. bacteria that are naturally associated with the oral cavity, formulations comprising the glutamine endopeptidase enzymes and the use thereof for the treatment, prevention of allergic reaction and diagnosis of gluten allergy related diseases such as Celiac Sprue, gluten allergy and/or dermatitis herpetiformis. |
| FILED | Thursday, October 07, 2010 |
| APPL NO | 13/500670 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.630 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685396 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Zhaochun Chen (Potomac, Maryland); Stephen Leppla (Bethesda, Maryland); Mahtab Moayeri (Bethesda, Maryland); Suzanne U. Emerson (Gaithersburg, Maryland); Robert H. Purcell (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Zhaochun Chen (Potomac, Maryland); Stephen Leppla (Bethesda, Maryland); Mahtab Moayeri (Bethesda, Maryland); Suzanne U. Emerson (Gaithersburg, Maryland); Robert H. Purcell (Gaithersburg, Maryland) |
| ABSTRACT | The present invention relates to monoclonal antibodies that bind or neutralize anthrax protective antigen (PA) toxin. The invention provides such antibodies, fragments of such antibodies retaining anthrax PA toxin-binding ability, fully human or humanized antibodies retaining anthrax PA toxin-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention. |
| FILED | Wednesday, December 21, 2005 |
| APPL NO | 11/793735 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/133.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685400 | Keane et al. |
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| FUNDED BY |
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| APPLICANT(S) | Robert W. Keane (Miami, Florida); W. Dalton Dietrich (Miami, Florida); Juan Pablo De Rivero Vaccari (Miami, Florida); Helen M. Bramlett (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Robert W. Keane (Miami, Florida); W. Dalton Dietrich (Miami, Florida); Juan Pablo De Rivero Vaccari (Miami, Florida); Helen M. Bramlett (Miami, Florida) |
| ABSTRACT | Compositions and methods for reducing inflammation in the central nervous system (CNS) of a mammal that has been subjected to a stroke, traumatic injury to the CNS such as traumatic brain injury (TBI), spinal cord injury (SCI), or having an autoimmune or CNS disease have been developed. The compositions and methods described herein include antibodies that specifically bind to at least one component (e.g., ASC, NALP1) in a mammalian inflammasome (e.g., the NALP1 inflammasome) and have use as treatments for SCI, TBI, stroke, and autoimmune and CNS diseases in a mammal. In a rodent model of SCI, therapeutic neutralization of ASC using a polyclonal antibody that specifically binds to ASC inhibited the inflammasome, reduced caspase-1 activation, XIAP cleavage, and interleukin processing, resulting in significant tissue sparing and functional improvement. Additionally, in a rodent model of TBI, neutralization of ASC after TBI reduced caspase-1 activation and XIAP cleavage. Further, in a rodent thromboembolic stroke model, neutralization of NLRP1 resulted in reduced histopathological damage in mice and reduced cytokine activation, suggesting that the inflammasome complex forms in the brain after stroke and is a therapeutic target for reducing the detrimental consequences of post-stroke inflammation. |
| FILED | Wednesday, July 30, 2008 |
| APPL NO | 12/182886 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/139.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685403 | Takada et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yoshikazu Takada (Davis, California); Jun Saegusa (Kobe, Japan) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yoshikazu Takada (Davis, California); Jun Saegusa (Kobe, Japan) |
| ABSTRACT | Interaction between insulin-like growth factor 1 (IGFI) and integrin is involved in integrin-mediated cellular signaling, such as enhanced proliferation of cells expressing integrins, especially integrin alpha v beta 3, alpha 6 beta. 1 and alpha 6. beta. 4. A method for inhibiting integrin signaling by using an inhibitor of IGFI-integrin binding is disclosed A method for identifying inhibitors of IGFI-integrin binding is also described. Further disclosed are polypeptides, nucleic acids, and corresponding compositions for inhibiting integrin signaling. |
| FILED | Friday, January 29, 2010 |
| APPL NO | 13/146907 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685404 | Loftis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jennifer Loftis (Portland, Oregon); Marilyn Huckans (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jennifer Loftis (Portland, Oregon); Marilyn Huckans (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
| ABSTRACT | Methods are provided for the treatment of subjects with cognitive or neuropsychiatric impairment induced by substance addiction and for increasing cognitive function in a subject with substance addiction. In some embodiments, the methods include administering to the subject a therapeutically effective amount of a major histocompatibility complex (MHC) molecule including covalently linked first, second, and third domains; wherein the first domain is an MHC class II β1 domain and the second domain is an MHC class II α1 domain; or wherein the first domain is an MHC class I α1 domain and the second domain is an MHC class I α2 domain; and wherein the third domain is covalently linked to the first domain and comprises an antigen of the central or peripheral nervous system. |
| FILED | Monday, January 30, 2012 |
| APPL NO | 13/361720 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685411 | Dormitzer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Philip R. Dormitzer (Cambridge, Massachusetts); Stephen C. Harrison (Cambridge, Massachusetts); Harry B. Greenberg (Palo Alto, California); Joshua Yoder (Newtown, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States of America as represented by the National Institutes of Health (NIH) (Washington, District of Columbia); The United States of America as represented by the Dept. of Health and Human Services (DHHS) (Washington, District of Columbia) |
| INVENTOR(S) | Philip R. Dormitzer (Cambridge, Massachusetts); Stephen C. Harrison (Cambridge, Massachusetts); Harry B. Greenberg (Palo Alto, California); Joshua Yoder (Newtown, Massachusetts) |
| ABSTRACT | The present invention relates to novel recombinant polypeptide antigens that may comprise subunit vaccines against rotavirus infection. Further, the present invention relates to methods for use of said antigens in the diagnosis, treatment and prevention of rotavirus infection. |
| FILED | Wednesday, January 03, 2007 |
| APPL NO | 11/649191 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/215.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685416 | Klinman et al. |
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| APPLICANT(S) | Dennis Klinman (Potomac, Maryland); Hidekazu Shirota (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Dennis Klinman (Potomac, Maryland); Hidekazu Shirota (Rockville, Maryland) |
| ABSTRACT | Methods for inducing an immune response to a tumor in a subject are disclosed herein. These methods include selecting a subject with a tumor and administering a therapeutically effective amount of apoptotic tumor cells conjugated to a CpG oligodexoynucleotide (ODN) to the subject. In some embodiments, the CpG ODN is a K-type or a D-type CpG ODN. Methods for treating a tumor in a subject are also disclosed herein. These methods include selecting a subject with a tumor and administering a therapeutically effective amount of apoptotic tumor cells conjugated to a CpG oligodexoynucleotide (ODN) to the subject. In some embodiments, the tumor cells are autologous. In additional embodiments, the tumor is a lymphoma, cervical cancer, prostate cancer, breast cancer, colon cancer or a lung cancer. |
| FILED | Tuesday, March 01, 2011 |
| APPL NO | 13/581999 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/277.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685634 | Boruch |
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| FUNDED BY |
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| APPLICANT(S) | Alan V. Boruch (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alan V. Boruch (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are compositions and methods useful for preparing neural scaffolds. The scaffolds comprise tissue taken from the spinal cord and/or dura mater of vertebrate and can be processed to form gels or sheets. Methods of treating patient with CNS injury are also presented. |
| FILED | Friday, March 05, 2010 |
| APPL NO | 12/718227 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685637 | Ostermeier et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | G. Charles Ostermeier (Frederick, Maryland); Jane S. Farley (Ellsworth, Maine); Robert Taft (Southwest Harbor, Maine); Michael V. Wiles (Mount Desert, Maine) |
| ABSTRACT | Described herein are kits for use in cryopreserving mammalian sperm including a composition that comprises a cryoprotectant; a membrane protectant that stabilizes or assists in stabilization of membranes of sperm; and monothioglycerol. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 13/723721 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685638 | Bhatia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sangeeta N. Bhatia (Lexington, Massachusetts); Christopher Flaim (San Diego, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sangeeta N. Bhatia (Lexington, Massachusetts); Christopher Flaim (San Diego, California) |
| ABSTRACT | Provided is a microarray platform for the culture of cells atop combinatorial matrix mixtures; enabling the study of differentiation in response to a multitude of microenvironments in parallel. |
| FILED | Thursday, January 19, 2006 |
| APPL NO | 11/336131 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685658 | Golemis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Erica A. Golemis (Oreland, Pennsylvania); Elena N. Pugacheva (Morgantown, West Virginia) |
| ASSIGNEE(S) | Fox Chase Cancer Center (Jenkintown, Pennsylvania) |
| INVENTOR(S) | Erica A. Golemis (Oreland, Pennsylvania); Elena N. Pugacheva (Morgantown, West Virginia) |
| ABSTRACT | Compositions and methods are provided for identifying agents which have efficacy for the treatment of disorders related to aberrant cilial structure and function, including polycystic kidney disease. |
| FILED | Tuesday, July 17, 2007 |
| APPL NO | 12/374209 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685659 | Zetter et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bruce R. Zetter (Wayland, Massachusetts); Adam S. Feldman (Brookline, Massachusetts); W. Scott McDougal (Manchester, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Bruce R. Zetter (Wayland, Massachusetts); Adam S. Feldman (Brookline, Massachusetts); W. Scott McDougal (Manchester, Massachusetts) |
| ABSTRACT | The present invention is based on the discovery that three proteins, Cystatin B, Chaperonin 10, and Profilin are present in the urine of patients with bladder cancer, a cancer of epithelial origin. Accordingly, the present invention is directed to methods for prognostic evaluation of cancers of epithelial origin and to methods for facilitating diagnosis of cancers of epithelial origin by monitoring the presence of these markers in biological samples. The invention is also directed to markers for therapeutic efficacy. |
| FILED | Monday, January 30, 2006 |
| APPL NO | 11/814939 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685660 | Vogelstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); D. Williams Parsons (Bellaire, Texas); Xiaosong Zhang (Baltimore, Maryland); Jimmy Cheng-Ho Lin (Baltimore, Maryland); Rebecca J. Leary (Baltimore, Maryland); Philipp Angenendt (Hamburg, Germany); Nickolas Papadopoulos (Towson, Maryland); Victor Velculescu (Dayton, Maryland); Giovanni Parmigiani (Boston, Massachusetts); Rachel Karchin (Towson, Maryland); Sian Jones (Baltimore, Maryland); Hai Yan (Chapel Hill, North Carolina); Darell Bigner (Mebane, North Carolina); Chien-Tsun Kuan (Cary, North Carolina); Gregory J. Riggins (White Hall, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); D. Williams Parsons (Bellaire, Texas); Xiaosong Zhang (Baltimore, Maryland); Jimmy Cheng-Ho Lin (Baltimore, Maryland); Rebecca J. Leary (Baltimore, Maryland); Philipp Angenendt (Hamburg, Germany); Nickolas Papadopoulos (Towson, Maryland); Victor Velculescu (Dayton, Maryland); Giovanni Parmigiani (Boston, Massachusetts); Rachel Karchin (Towson, Maryland); Sian Jones (Baltimore, Maryland); Hai Yan (Chapel Hill, North Carolina); Darell Bigner (Mebane, North Carolina); Chien-Tsun Kuan (Cary, North Carolina); Gregory J. Riggins (White Hall, Maryland) |
| ABSTRACT | We found mutations of the R132 residue of isocitrate dehydrogenase 1 (IDH1) in the majority of grade II and III astrocytomas and oligodendrogliomas as well as in glioblastomas that develop from these lower grade lesions. Those tumors without mutations in IDH1 often had mutations at the analogous R172 residue of the closely related IDH2 gene. These findings have important implications for the pathogenesis and diagnosis of malignant gliomas. |
| FILED | Thursday, September 03, 2009 |
| APPL NO | 13/060191 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685666 | Cao |
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| FUNDED BY |
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| APPLICANT(S) | Deliang Cao (Chatham, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of Southern Illinois University (Springfield, Illinois) |
| INVENTOR(S) | Deliang Cao (Chatham, Illinois) |
| ABSTRACT | This invention provides antibodies immunologically specific for human ARL-1 (also referred to AKR1B10), a species of the aldo-keto reductase superfamily of proteins. The invention also provides methods of making and methods of using said antibodies. |
| FILED | Monday, January 31, 2011 |
| APPL NO | 13/017618 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/40.520 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685668 | Minea et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Radu O. Minea (Arcadia, California); Francis S. Markland, Jr. (Manhattan Beach, California) |
| ABSTRACT | This invention relates to methods of expressing eukaryotic proteins in prokaryotic hosts, particularly eukaryotic proteins that require formation of disulfide bridges for biological activity. Various approaches are used including fusion to thioredoxin, cytoplasmic expression of disulfide isomerases, deficiencies in thioredoxin and/or glutathione reductases, deficiencies in proteases, and the like. The method is applicable to express monomeric and dimeric forms of the eukaryotic protein with biological activity such as monomeric and dimeric forms of a disintegrin or a disintegrin domain. Included are the vectors, host cells expressing the proteins, the expressed proteins and methods of using the proteins. |
| FILED | Tuesday, November 20, 2012 |
| APPL NO | 13/682470 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685722 | Chiorini et al. |
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| FUNDED BY |
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| APPLICANT(S) | John A. Chiorini (Dayton, Maryland); Michael Schmidt (Kensington, Maryland); Ioannis Bossis (Columbia, Maryland); Giovanni Di Pasquale (Kensington, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | John A. Chiorini (Dayton, Maryland); Michael Schmidt (Kensington, Maryland); Ioannis Bossis (Columbia, Maryland); Giovanni Di Pasquale (Kensington, Maryland) |
| ABSTRACT | The present invention provides a bovine adeno-associated virus (BAAV) virus and vectors and particles derived therefrom. In addition, the present invention provides methods of delivering a nucleic acid to a cell using the BAAV vectors and particles. |
| FILED | Tuesday, March 06, 2012 |
| APPL NO | 13/413321 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685727 | Chaudhuri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aadel Chaudhuri (Santa Clara, California); Alex Steven So (Los Angeles, California); David Baltimore (Pasadena, California); Ryan M. O'Connell (Salt Lake City, Utah) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Aadel Chaudhuri (Santa Clara, California); Alex Steven So (Los Angeles, California); David Baltimore (Pasadena, California); Ryan M. O'Connell (Salt Lake City, Utah) |
| ABSTRACT | The present disclosure relates to regulation of macrophage activation by delivering of miRNAs, for example miR-125b or anti-miR-125b, to macrophages. For example, in some embodiments, macrophage activation can be elevated or reduced by administering miR-125b or anti-miR-125b oligonucleotides. Also disclosed are methods for promoting T cell activation and method for treating various disorders such as tumor and autoimmune diseases. |
| FILED | Monday, June 18, 2012 |
| APPL NO | 13/526347 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685729 | Clark et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Douglas S. Clark (Orinda, California); Timothy Whitehead (Berkeley, California); Frank T. Robb (Gaithersburg, Maryland); Pongpan Laksanalamai (Baltimore, Maryland); Anchalee Jiemjit (Baltimore, Maryland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Douglas S. Clark (Orinda, California); Timothy Whitehead (Berkeley, California); Frank T. Robb (Gaithersburg, Maryland); Pongpan Laksanalamai (Baltimore, Maryland); Anchalee Jiemjit (Baltimore, Maryland) |
| ABSTRACT | The invention provides methods and compositions for increasing tolerance of microorganisms to toxic agents, such as solvents; and for increasing production of solvents from solvent-generating microorganisms. The methods comprise engineering a microorganism of interest to express a heterologous heat-shock protein/chaperone, e.g., Group II chaperonin or a prefoldin such as γ-prefoldin, where the heterologous protein is from an extremophile, such as an archaean. |
| FILED | Tuesday, February 26, 2008 |
| APPL NO | 12/528620 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685730 | Odorico et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jon Odorico (Madison, Wisconsin); Xiaofang Xu (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Jon Odorico (Madison, Wisconsin); Xiaofang Xu (Madison, Wisconsin) |
| ABSTRACT | Methods and devices for culturing human pluripotent stem cells to produce cells of the pancreatic lineage are disclosed. The methods include steps of culturing the stem cells under conditions that induce the expression of mesendoderm/primitive streak and definitive endoderm markers in a chemically defined medium including an effective amount of i) fibroblast growth factor, ii) Activin A, and iii) bone morphogenetic protein. The methods further include the steps of culturing cells under conditions favoring the formation of at least one of intact embryoid bodies and pancreatic progenitor PDX1+Ins− cells. |
| FILED | Friday, June 08, 2012 |
| APPL NO | 13/492244 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685740 | Rabinovitch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nathan Rabinovitch (Denver, Colorado); Erwin Gelfand (Englewood, Colorado) |
| ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
| INVENTOR(S) | Nathan Rabinovitch (Denver, Colorado); Erwin Gelfand (Englewood, Colorado) |
| ABSTRACT | The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and the subject's level of eosinophilic airway inflammation and identifying a subject with a high ratio of CysLT levels to eosinophilic airway inflammation as susceptible to treatment with the leukotriene modifier. Also discussed is a method of treatment of subjects who are susceptible to treatment that includes administering a leukotriene modifier to such a subject. |
| FILED | Monday, March 16, 2009 |
| APPL NO | 12/404984 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/71 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08685743 — Real-time, single-step bioassay using nanoplasmonic resonator with ultra-high sensitivity
| US 08685743 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ABSTRACT | A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/772118 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685754 | Pollack et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael G. Pollack (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina); Vijay Srinivasan (Durham, North Carolina); Richard B. Fair (Durham, North Carolina) |
| ASSIGNEE(S) | Advanced Liquid Logic, Inc. (Morrisville, North Carolina); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael G. Pollack (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina); Vijay Srinivasan (Durham, North Carolina); Richard B. Fair (Durham, North Carolina) |
| ABSTRACT | Droplet actuator devices and methods for immunoassays and washing are provided. According to one embodiment, a method of providing a droplet in contact with a surface of a super paramagnetic bead with a reduced concentration of a substance is provided and includes: (a) providing a super paramagnetic bead in contact with a droplet comprising a starting concentration and starting quantity of the substance and having a starting volume; (b) conducting one or more droplet operations to merge a wash droplet with the droplet provided in step (a) to yield a combined droplet; and (c) conducting one or more droplet operations to divide the combined droplet to yield a set of droplets. The set of droplets includes: (i) a droplet in contact with the super paramagnetic bead having a decreased concentration of the substance relative to the starting concentration; and (ii) a droplet which is separated from the super paramagnetic bead. |
| FILED | Thursday, February 26, 2009 |
| APPL NO | 12/393534 |
| ART UNIT | 1677 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/526 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685755 | Ferrari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugar Land, Texas); Ennio Tasciotti (Houston, Texas); Ali Bouamrani (Grenoble, France); Ye Hu (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugar Land, Texas); Ennio Tasciotti (Houston, Texas); Ali Bouamrani (Grenoble, France); Ye Hu (Austin, Texas) |
| ABSTRACT | A new fractionation device shows desirable features for exploratory screening and biomarker discovery. The constituent MSCs may be tailored for desired pore sizes and surface properties and for the sequestration and enrichment of extremely low abundant protein and peptides in desired ranges of the mass/charge spectrum. The MSCs are effective in yielding reproducible extracts from complex biological samples as small as 10 μl in a time as short as 30 minutes. They are inexpensive to manufacture, and allow for scaled up production to attain the simultaneous processing of a large number of samples. The MSCs are multiplexed, label-free diagnostic tools with the potential of biological recognition moiety modification for enhanced specificity. The MSCs may store, protect and stabilize biological fluids, enabling the simplified and cost-effective collection and transportation of clinical samples. The MSC-based device may serve as a diagnostic tool to complement histopathology, imaging, and other conventional clinical techniques. The MSCs mediated identification of disease-specific protein signatures may help in the selection of personalized therapeutic combinations, in the real-time assessment of therapeutic efficacy and toxicity, and in the rational modulation of therapy based on the changes in the protein networks associated with the prognosis and the drug resistance of the disease. |
| FILED | Tuesday, July 20, 2010 |
| APPL NO | 12/839606 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/527 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685921 | Du |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiaoping Du (Willowbrook, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Xiaoping Du (Willowbrook, Illinois) |
| ABSTRACT | Provided herein are compounds that inhibit a binding interaction between a β integrin and a G protein subunit, as well as compositions, e.g., pharmaceutical compositions, comprising the same, and related kits. In some embodiments, the compound is an antibody or antibody analog, and, in other embodiments, the compound is a peptide or peptide analog. Also provided are methods of using the compounds, including methods of treating or preventing a medical condition, such as stroke, heart attack, cancer, or inflammation. |
| FILED | Saturday, September 15, 2012 |
| APPL NO | 13/621064 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685925 | Tymianski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael Tymianski (Toronto, Canada) |
| ASSIGNEE(S) | Nono Inc. (Ontario, Canada) |
| INVENTOR(S) | Michael Tymianski (Toronto, Canada) |
| ABSTRACT | The invention provides methods of treating stroke and related conditions exacerbated by fever and/or hyperglycemia by administering peptides or peptidomimetics that inhibit binding of NMDAR 2B to PSD-95 to a patient. |
| FILED | Tuesday, July 10, 2007 |
| APPL NO | 12/307581 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685929 | Albertson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donna G. Albertson (Lafayette, California); Daniel Pinkel (Walnut Creek, California); Colin Collins (San Rafael, California); Joe W. Gray (San Francisco, California); Bauke Ylstra (San Francisco, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Donna G. Albertson (Lafayette, California); Daniel Pinkel (Walnut Creek, California); Colin Collins (San Rafael, California); Joe W. Gray (San Francisco, California); Bauke Ylstra (San Francisco, California) |
| ABSTRACT | This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer (e.g., breast cancer). Using this information, this invention provides methods of detecting a predisposition to cancer in an animal. The methods involve (i) providing a biological sample from an animal (e.g. a human patient); (ii) detecting the level of CYP24 within the biological sample; and (iii) comparing the level of CYP24 with a level of CYP24 in a control sample taken from a normal, cancer-free tissue where an increased level of CYP24 in the biological sample compared to the level of CYP24 in the control sample indicates the presence of said cancer in said animal. |
| FILED | Tuesday, April 10, 2012 |
| APPL NO | 13/443639 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685936 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Charles D. Smith (Mount Pleasant, South Carolina); Yan Zhuang (Hershey, Pennsylvania); Lynn W. Maines (Hummelstown, Pennsylvania) |
| ASSIGNEE(S) | Apogee Biotechnology Corporation (Hershey, Pennsylvania) |
| INVENTOR(S) | Charles D. Smith (Mount Pleasant, South Carolina); Yan Zhuang (Hershey, Pennsylvania); Lynn W. Maines (Hummelstown, Pennsylvania) |
| ABSTRACT | The invention relates to prodrugs of hydroxyl-substituted adamantane compounds, pharmaceutical compositions thereof, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease. |
| FILED | Friday, March 12, 2010 |
| APPL NO | 13/255813 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685938 | Goronzy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jorg J Goronzy (Palo Alto, California); Cornelia Weyand (Palo Alto, California); Mingcan Yu (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jorg J Goronzy (Palo Alto, California); Cornelia Weyand (Palo Alto, California); Mingcan Yu (Palo Alto, California) |
| ABSTRACT | The present invention provides methods for restoring or enhancing T cell mediated immune response in individuals of middle and advanced age. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/082790 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685939 | Wei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wei-Zen Wei (Grosse Pointe Farms, Michigan); Gen Sheng Wu (Troy, Michigan); Marie P. Piechocki (Fraser, Michigan); Richard F. Jones (Fayetteville, New York) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Wei-Zen Wei (Grosse Pointe Farms, Michigan); Gen Sheng Wu (Troy, Michigan); Marie P. Piechocki (Fraser, Michigan); Richard F. Jones (Fayetteville, New York) |
| ABSTRACT | The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host. |
| FILED | Friday, November 06, 2009 |
| APPL NO | 13/128046 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685941 | Turkson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Turkson (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | James Turkson (Orlando, Florida) |
| ABSTRACT | Disclosed herein are compositions comprising a drug combination that comprises ZD and S3I-201, Das and S3I-201, ZD and AG490, or Das and AG490. The disclosed drug combinations target two or more functional elements such as EGFR or Src and Stat3 or Jaks in pancreatic cancer cells. Also disclosed herein are methods of using the disclosed compositions to cytotoxically affect pancreatic cancer cells and methods of making the disclosed compositions. |
| FILED | Monday, November 30, 2009 |
| APPL NO | 13/131840 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/49 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685946 | Hutvágner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | György Hutvágner (Worcester, Massachusetts); Phillip D. Zamore (Northboro, Massachusetts) |
| ASSIGNEE(S) | Universiy of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | György Hutvágner (Worcester, Massachusetts); Phillip D. Zamore (Northboro, Massachusetts) |
| ABSTRACT | The present invention relates to the discovery of a method for inhibiting RNA silencing in a target sequence-specific manner. RNA silencing requires a set of conserved cellular factors to suppress expression of gene-encoded polypeptide. The invention provides compositions for sequence-specific inactivation of the RISC component of the RNA silencing pathway, and methods of use thereof. The RISC inactivators of the present invention enable a variety of methods for identifying and characterizing miRNAs and siRNAs, RISC-associated factors, and agents capable of modulating RNA silencing. Therapeutic methods and compositions incorporating RISC inactivators and therapeutic agents identified through use of RISC inactivators are also featured. |
| FILED | Friday, November 26, 2004 |
| APPL NO | 10/998364 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/55 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685951 | Basnakian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexei G. Basnakian (Little Rock, Arkansas); Richard B. Walker (North Little Rock, Arkansas); John R. J. Sorenson deceased (Little Rock, Arkansas); Anne S. Martin (Tallahassee, Florida) |
| ASSIGNEE(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Alexei G. Basnakian (Little Rock, Arkansas); Richard B. Walker (North Little Rock, Arkansas); John R. J. Sorenson deceased (Little Rock, Arkansas) |
| ABSTRACT | The present invention provides compositions and methods for cytoprotection. In particular, it provides zinc chelate compositions comprising at least one zinc ion and at least one aminothiol ligand. |
| FILED | Wednesday, March 26, 2008 |
| APPL NO | 12/055790 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/181 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685954 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth C. Anderson (Wellesley, Massachusetts); Teru Hideshima (Brookline, Massachusetts); Constantine S. Mitsiades (Boston, Massachusetts); Nicholas Mitsiades (Roxbury, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kenneth C. Anderson (Wellesley, Massachusetts); Teru Hideshima (Brookline, Massachusetts); Constantine S. Mitsiades (Boston, Massachusetts); Nicholas Mitsiades (Roxbury, Massachusetts) |
| ABSTRACT | The present invention relates to therapeutic compositions for treating cancer or preventing the growth of cancer cells, e.g., tumor growth, in a subject. The present invention also relates to methods for treating cancer, e.g., inhibiting tumor growth, in a subject who has become resistant to treatment, by administering to a subject an effective amount of a proteasome inhibitor and an effective amount of a therapeutic agent, e.g., a chemotherapeutic agent. The present invention further relates to methods for purging bone marrow, i.e., removing cancer cells from bone marrow, by exposing the bone marrow cells to a proteasome inhibitor and a therapeutic agent, e.g., a chemotherapeutic agent. |
| FILED | Friday, September 23, 2011 |
| APPL NO | 13/242209 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685956 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hong-Hsing Liu (Santa Clara, California); Gary Allen Peltz (Redwood City, California); Guochun Liao (Belmont, California); Timothy Alan Garrow (Mahomet, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois); The Board of Trustees of The Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Hong-Hsing Liu (Santa Clara, California); Gary Allen Peltz (Redwood City, California); Guochun Liao (Belmont, California); Timothy Alan Garrow (Mahomet, Illinois) |
| ABSTRACT | The present disclosure relates generally to a pharmaceutical compositions and methods of reducing acetaminophen-induced liver toxicity. The disclosure includes pharmaceutical compositions including acetaminophen and one or more components selected from S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof. The disclosure also relates to methods of reducing acetaminophen-induced liver toxicity in a subject by administering or co-administering one or more of S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof, with acetaminophen to a subject. |
| FILED | Thursday, September 16, 2010 |
| APPL NO | 13/395736 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685963 | Landry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donald W. Landry (New York, New York); Shi Xian Deng (White Plains, New York); Gangli Gong (Little Neck, New York); Yuli Xie (New York, New York); Yidong Liu (New York, New York); K. Alison Rinderspacher (Bronx, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the city of New York (New York, New York) |
| INVENTOR(S) | Donald W. Landry (New York, New York); Shi Xian Deng (White Plains, New York); Gangli Gong (Little Neck, New York); Yuli Xie (New York, New York); Yidong Liu (New York, New York); K. Alison Rinderspacher (Bronx, New York) |
| ABSTRACT | The present invention relates to compounds with activity as BACE1 and NFκB modulators, and methods for treating, preventing, or ameliorating neurodegenerative diseases, such as Alzheimer's disease. The present invention is also directed to the treatment of diseases related to dysfunction of cell proliferation, the immune system and/or inflammation using such compounds or pharmaceutical compositions containing such candidate compounds. |
| FILED | Tuesday, April 26, 2011 |
| APPL NO | 13/094504 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/224.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685966 | Blagg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian S. J. Blagg (Lawrence, Kansas); Adam S. Duerfeldt (San Diego, California) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Brian S. J. Blagg (Lawrence, Kansas); Adam S. Duerfeldt (San Diego, California) |
| ABSTRACT | The present disclosure provides a series of compounds which exhibit isoform selective inhibition of GRP94, a homologue of Hsp90 that is localized to the endoplasmic recticulum. Through GRP94 inhibition, these compounds are likely to manifest anti-cancer, anti-inflammatory, anti-metastasis, and immunosuppressive activities, as well as utility in the treatment of neurodegenerative diseases, and diabetes. |
| FILED | Friday, April 06, 2012 |
| APPL NO | 13/441568 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/230.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685978 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Richard E. Lee (Cordova, Tennessee); Jianjun Qi (Houston, Texas); Julian G. Hurdle (Euless, Texas); Bernd Meibohm (Germantown, Tennessee); Vnr Pavan Kumar Vaddady (Memphis, Tennessee); Rakesh (Cordova, Tennessee); Jiuyu Liu (Bartlett, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Richard E. Lee (Cordova, Tennessee); Jianjun Qi (Houston, Texas); Julian G. Hurdle (Euless, Texas); Bernd Meibohm (Germantown, Tennessee); Vnr Pavan Kumar Vaddady (Memphis, Tennessee); Rakesh (Cordova, Tennessee); Jiuyu Liu (Bartlett, Tennessee) |
| ABSTRACT | Novel 3′-deoxy-3′-acylaminospectinomycin compounds are described. Also described are methods of using the 3′-deoxy-3-acylaminospectinomycin compounds and other spectinomycin analogs in treating tuberculosis and in treating microbial infections. |
| FILED | Monday, July 26, 2010 |
| APPL NO | 12/843551 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/252.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686003 | Millan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jose Luis Millan (La Jolla, California); Eduard Sergienko (La Jolla, California) |
| ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| INVENTOR(S) | Jose Luis Millan (La Jolla, California); Eduard Sergienko (La Jolla, California) |
| ABSTRACT | Disclosed herein are compounds that are tissue-nonspecific alkaline phosphatase inhibitors. The disclosed compounds are used to treat, prevent, or abate vascular calcification, arterial calcification and other cardiovascular diseases. |
| FILED | Wednesday, December 07, 2011 |
| APPL NO | 13/313756 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/313 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686008 | McCurdy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher R. McCurdy (Oxford, Mississippi); Christophe Mesangeau (Oxford, Mississippi); Rae Reiko Matsumoto (Morgantown, West Virginia); Jacques Henri Poupaert (Brussels, Belgium); Bonnie Ann Avery (Oxford, Mississippi); Ahmed Hassan Amin Abdelazeem (Oxford, Mississippi) |
| ASSIGNEE(S) | The University of Mississippi (University, Michigan); L'Universite Catholique de Louvain (Louvain-la-Neuve, Belgium) |
| INVENTOR(S) | Christopher R. McCurdy (Oxford, Mississippi); Christophe Mesangeau (Oxford, Mississippi); Rae Reiko Matsumoto (Morgantown, West Virginia); Jacques Henri Poupaert (Brussels, Belgium); Bonnie Ann Avery (Oxford, Mississippi); Ahmed Hassan Amin Abdelazeem (Oxford, Mississippi) |
| ABSTRACT | Compounds having the general formula II, III, or IV wherein R1 can be a radical of an optionally substituted C-4 to C-7 N-containing heterocycle or a radical of an optionally substituted cyclic or acyclic tertiary amine or isoindoline-1,3-dione: R2,3,4,5,6 can each independently be any one or combinations of the following moieties, cyano, nitro, acyl, alkyl, amido, azido, isothiocyanate, isocyanate, optionally substituted anilino, halogens, ethers, sulfonamides, thioacyl, nitro, aromatic, heterocyclic, olefinic, acetylene, deuterium, or tritium; Y can be either CH, CH2, O, S, OCH2, N—R, N—Ar, C—R, C—Ar; Z can be either H, O, S, S—R or NR. R groups can be either H, aryls, alkyls, or cycloalkyls; “n” can be 1 to 5 carbons in length and stereoisomers, functional analogs, and pharmaceutically acceptable salts thereof and wherein the moiety bridging R1 and N can be a substituted alkylene, optionally substituted alkenylene or optionally substituted alkynylene and where the alkylene group can include an inserted C3-C5 cycloalkyl group, aromatic, and hetercocyclic group; wherein X′ is halogen, or C1-C4 haloalyl; wherein the Rx is a C1-C5 straight chain or branched chain alkyl or a C1-C4 straight chain or branched chain haloalkyl. |
| FILED | Friday, May 21, 2010 |
| APPL NO | 12/785217 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/367 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686012 | Olson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Eric N. Olson (Dallas, Texas); Douglas Frantz (Boerne, Texas); Jenny Hsieh (Irving, Texas); Steven L. McKnight (Dallas, Texas); Jay Schneider (Coppell, Texas) |
| ABSTRACT | The present invention relates to screens for compounds that can induce stem cell differentiation. In addition, isoxazoles and sulfonyl hydrazones are identified as general classes of compounds that can induce differentiation of stem cells into cells of neuronal and cardiac fate, respectively. |
| FILED | Monday, November 12, 2012 |
| APPL NO | 13/674710 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/372 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686016 | Reilly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karlyne Reilly (Potomac, Maryland); Thomas Turbyville (Frederick, Maryland); John A. Beutler (Union Bridge, Maryland); David Wiemer (Iowa City, Iowa) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Karlyne Reilly (Potomac, Maryland); Thomas Turbyville (Frederick, Maryland); John A. Beutler (Union Bridge, Maryland); David Wiemer (Iowa City, Iowa) |
| ABSTRACT | Disclosed is a method for preventing or treating an undesirable condition in a subject carrying cells homozygous null for the neurofibromatosis type 1 gene or subjects that are haploinsufficient for the neurofibromatosis type 1 gene, the method comprising administering to a subject in need thereof an effective amount of a schweinfurthin or schweinfurthin analog or derivative, or a pharmaceutically acceptable salt, prodrug, hydrate, or solvate thereof. Also disclosed is a new schweinfurthin compound of the formula. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 13/266841 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/388 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686038 | Yang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tianxin Yang (Salt Lake City, Utah) |
| ASSIGNEE(S) | The Univsersity of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Tianxin Yang (Salt Lake City, Utah) |
| ABSTRACT | The present invention relates to methods of treating the side effects of a toxic medical therapy using nitrated lipids. In particular, the methods comprise the use of nitrated fatty acids or esters thereof to treat side effects, including organ system damage, caused by chemotherapy, radiotherapy, and the administration of other toxic agents. |
| FILED | Thursday, June 18, 2009 |
| APPL NO | 12/996848 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/560 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686041 | Ilan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yaron Ilan (Jerusalem, Israel); Ehud Zigmond (Jerusalem, Israel); Richard B. Silverman (Northbrook, Illinois); Hejun Lu (Shanghai, China PRC) |
| ASSIGNEE(S) | Hadasit Medical Research Services and Development, Ltd. (Jerusalem, Israel); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Yaron Ilan (Jerusalem, Israel); Ehud Zigmond (Jerusalem, Israel); Richard B. Silverman (Northbrook, Illinois); Hejun Lu (Shanghai, China PRC) |
| ABSTRACT | The invention relates to inhibition of ornithine aminotransferase (OAT) for suppression of tumor cells proliferation. More particularly, the invention relates to methods of treatment of proliferative disorders by the selective inhibition of OAT, and further provides the use of OAT inhibitors, specifically, 5-amino-1,3-hexadienyl-carboxylic acid (Gabaculine), and Gabaculine analogue 8, for compositions and methods for the treatment of proliferative disorders such as hepatocellular carcinoma. The invention further provides methods and kits for the diagnosis of a pathologic proliferative disorder in a mammalian subject, based on determining the level of OAT expressed in a biological sample obtained from a subject. |
| FILED | Thursday, May 31, 2012 |
| APPL NO | 13/484392 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/573 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686045 | Longo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ABSTRACT | Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. |
| FILED | Thursday, June 08, 2006 |
| APPL NO | 11/449381 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/616 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686046 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevin R. Lynch (Charlottesville, Virginia); Timothy L. Macdonald (Charlottesville, Virginia); Yugesh Kharel (Charlottesville, Virginia); Thomas P. Mathews (San Diego, Virginia); Brian R. Wamhoff (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Kevin R. Lynch (Charlottesville, Virginia); Timothy L. Macdonald (Charlottesville, Virginia); Yugesh Kharel (Charlottesville, Virginia); Thomas P. Mathews (San Diego, Virginia); Brian R. Wamhoff (Charlottesville, Virginia) |
| ABSTRACT | Amidine analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumor cells. |
| FILED | Saturday, October 02, 2010 |
| APPL NO | 12/896881 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/617 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686115 | Cho |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wonhwa Cho (Lisle, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Wonhwa Cho (Lisle, Illinois) |
| ABSTRACT | Provided herein are fluorescent lipid binding proteins (FLBPs). The FLBPs comprise a lipid binding domain linked to a fluorophore, whrereby the fluorophore's fluorescence emission undergoes a spectral change upon lipid binding. the fluorophore is selected from the group consisting of 2-dimethylamino-6-acyl-naphthalene (DAN) and RED fluorophore and the lipid binding protein is selected from the group consisting of ENTH domain of epsin 1, C2 domain of bovine lactadherin, C 1B domain of protein kinase C-gamma, C2 domain of cytosolic phospholipase A2-beta, and PH domain of Bruton's tyrosine kinase PH. |
| FILED | Friday, November 05, 2010 |
| APPL NO | 13/508381 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686146 | Cushman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark S. Cushman (West Lafayette, Indiana); Evgeny A. Kiselev (West Lafayette, Indiana); Andrew E. Morrell (San Diego, California) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Mark S. Cushman (West Lafayette, Indiana); Evgeny A. Kiselev (West Lafayette, Indiana); Andrew E. Morrell (San Diego, California) |
| ABSTRACT | The invention described herein pertains to substituted azaindenoisoquinoline compounds, in particular 7-, 8-, 9-, and 10-azaindenoisoquinoline compounds, which are inhibitors of topoisomerase I, processes and intermediates for their syntheses, pharmaceutical compositions of the compounds, and methods of using them in the treatment of cancer. |
| FILED | Friday, July 13, 2012 |
| APPL NO | 13/548579 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/48 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686359 | Zewail |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ahmed H. Zewail (Pasadena, California) |
| ABSTRACT | The present invention relates to methods and systems for 4D ultrafast electron microscopy (UEM)—in situ imaging with ultrafast time resolution in TEM. Single electron imaging is used as a component of the 4D UEM technique to provide high spatial and temporal resolution unavailable using conventional techniques. Other embodiments of the present invention relate to methods and systems for convergent beam UEM, focusing the electron beams onto the specimen to measure structural characteristics in three dimensions as a function of time. Additionally, embodiments provide not only 4D imaging of specimens, but characterization of electron energy, performing time resolved electron energy loss spectroscopy (EELS). |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/864113 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686727 | Reddy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ravinder Reddy (Gladwyne, Pennsylvania); Hari Hariharan (Mount Laurel, New Jersey); Mohammad Haris (Philadelphia, Pennsylvania); Kejia Cai (Elkins Park, Pennsylvania); Anup Singh (Philadelphia, Pennsylvania); Feliks Kogan (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ravinder Reddy (Gladwyne, Pennsylvania); Hari Hariharan (Mount Laurel, New Jersey); Mohammad Haris (Philadelphia, Pennsylvania); Kejia Cai (Elkins Park, Pennsylvania); Anup Singh (Philadelphia, Pennsylvania); Feliks Kogan (Philadelphia, Pennsylvania) |
| ABSTRACT | The CEST effect for various neurotransmitters and energy metabolites in the brain and muscles and various endogenous metabolites in the liver, brain, and myocardium are imaged using MR imaging to illustrate a unique CEST effect that may be used to monitor the concentration of the metabolite and hence to characterize and monitor various disease states in the body correlated to the concentration of that metabolite. By adjusting the timing, amplitude, and length of the RF pulse as well as other parameters of the CEST pulse sequence to address the unique chemical shifts and exchange rates of the target, new targets with unique characteristics may be acquired using CEST MR imaging. |
| FILED | Wednesday, July 20, 2011 |
| APPL NO | 13/186981 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687869 | Liang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerome Z. Liang (Stony Brook, New York); Zigang Wang (Knoxville, Tennessee) |
| ASSIGNEE(S) | The Research Foundation of State of University of New York (New York, New York) |
| INVENTOR(S) | Jerome Z. Liang (Stony Brook, New York); Zigang Wang (Knoxville, Tennessee) |
| ABSTRACT | A method for reconstructing an image from emission data includes generating a compressed point-spread function matrix, generating an accumulated attenuation factor; and performing at least one image projection operation on an image matrix of the emission data using the compressed point-spread function matrix and the accumulated attenuation factor. The image projection operation can include rotating an image matrix and an exponential attenuation map to align with a selected viewing angle. An accumulated attenuation image is then generated from the rotated image matrix and rotated exponential attenuation map and a projection image is generated for each voxel by multiplying the accumulated attenuation image and point spread function matrix for each voxel. The rotating and multiplying operations can be performed on a graphics processing unit, which may be found in a commercially available video processing card, which are specifically designed to efficiently perform such operations. |
| FILED | Thursday, November 30, 2006 |
| APPL NO | 12/095662 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Image analysis 382/131 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08683755 | Spence et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian R Spence (Solvang, California); Stephen F White (Ventura, California) |
| ASSIGNEE(S) | Deployable Space Systems, Inc. (Goleta, California) |
| INVENTOR(S) | Brian R Spence (Solvang, California); Stephen F White (Ventura, California) |
| ABSTRACT | A directionally-controlled roll-out elastically deployable solar array structure is disclosed. The structure includes one or more longitudinal elastic roll out booms that may be closed section or open section to allow for efficient rolled packaging onto a lateral mandrel. A flexible photovoltaic blanket is attached to a tip structure and to a lateral base support structure, but remains uncoupled from the longitudinal booms. The solar array system may be stowed simultaneously into a rolled package comprised of the roll out booms and the flexible planar blanket together, or onto independent rolls. Alternatively, the system may be stowed by rolling the booms, and accordion Z-folding the hinged flexible photovoltaic blanket into a flat stack. Structural deployment is motivated by the elastic strain energy of the roll out booms, and several methods of deployment direction control are provided to ensure a known, controlled, and unidirectional deployment path of the elastically unrolling booms. |
| FILED | Thursday, January 20, 2011 |
| APPL NO | 13/010739 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Static structures 052/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08683862 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew Wang (San Diego, California); Paul D. Swanson (Santee, California); Richard L. Waters (San Diego, California); Maxwell Mayekawa Kerber (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Wang (San Diego, California); Paul D. Swanson (Santee, California); Richard L. Waters (San Diego, California); Maxwell Mayekawa Kerber (San Diego, California) |
| ABSTRACT | An oscillation apparatus comprising: a frame; a first proof mass coupled to the frame via a spring; a driving circuit operatively coupled to the first proof mass and the frame, wherein the driving circuit is configured to induce oscillatory motion of the first proof mass relative to the frame at a resonant frequency in a first direction; a first electron-tunneling position switch operatively coupled to the first proof mass such that the first position switch is configured to pass through a closed state during each oscillation of the proof mass, wherein the position switch comprises first and second single-atom-thick tunneling electrodes; and a sensing circuit coupled to the position switch, the sensing circuit configured to output a signal whenever the position switch passes through the closed state. |
| FILED | Thursday, November 03, 2011 |
| APPL NO | 13/288841 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684040 | Bernitsas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael M. Bernitsas (Saline, Michigan); Kamaldev Raghavan (Houston, Texas) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Michael M. Bernitsas (Saline, Michigan); Kamaldev Raghavan (Houston, Texas) |
| ABSTRACT | Roughness is added to the surface of a bluff body in a relative motion with respect to a fluid. The amount, size, and distribution of roughness on the body surface is controlled passively or actively to modify the flow around the body and subsequently the Vortex Induced Forces and Motion (VIFM). The added roughness, when designed and implemented appropriately, affects in a predetermined way the boundary layer, the separation of the boundary layer, the level of turbulence, the wake, the drag and lift forces, and consequently the Vortex Induced Motion (VIM), and the fluid-structure interaction. The goal of surface roughness control is to decrease/suppress Vortex Induced Forces and Motion. Suppression is required when fluid-structure interaction becomes destructive as in VIM of flexible cylinders or rigid cylinders on elastic support, such as underwater pipelines, marine risers, tubes in heat exchangers, nuclear fuel rods, cooling towers, SPAR offshore platforms. |
| FILED | Thursday, May 22, 2008 |
| APPL NO | 12/125409 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/808 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684101 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alfred David Johnson (San Leandro, California); Roger Graham Gilbertson (Novato, California); Valery Martynov (San Francisco, California) |
| ASSIGNEE(S) | TiNi Alloy Company (Berkeley, California) |
| INVENTOR(S) | Alfred David Johnson (San Leandro, California); Roger Graham Gilbertson (Novato, California); Valery Martynov (San Francisco, California) |
| ABSTRACT | A temperature-activated valve for a conventional fire sprinkler utilizing a hyperelastic single-crystal shape memory alloy is described. The shape-memory element expands as it is heated, forcing a bolt to break, thereby opening the sprinkler valve. The devices described are less susceptible to accidental breakage than conventional actuators, and have fewer moving parts. Transition temperature of the shape memory alloy can be tuned to a narrow range. |
| FILED | Thursday, January 24, 2008 |
| APPL NO | 12/019553 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fire extinguishers 169/37 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684187 | Buschmann |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne E. Buschmann (Boulder, Colorado) |
| ASSIGNEE(S) | Eltron Research and Development, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Wayne E. Buschmann (Boulder, Colorado) |
| ABSTRACT | A polyamide membrane including reaction product of an anhydrous solution comprising an anhydrous solvent, at least one polyfunctional secondary amine and a pre-polymer deposition catalyst, and an anhydrous, organic solvent solution comprising a polyfunctional aromatic amine-reactive reactant having one ring. A composite semipermeable membrane including the polyamide membrane on a porous support. |
| FILED | Monday, March 05, 2012 |
| APPL NO | 13/412538 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/500.380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684189 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liang Chen (Cambridge, Massachusetts); Lev E. Bromberg (Swampscott, Massachusetts); Trevor Alan Hatton (Sudbury, Massachusetts); Gregory C. Rutledge (Newton, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Liang Chen (Cambridge, Massachusetts); Lev E. Bromberg (Swampscott, Massachusetts); Trevor Alan Hatton (Sudbury, Massachusetts); Gregory C. Rutledge (Newton, Massachusetts) |
| ABSTRACT | Described is the application of layer-by-layer (LbL) electrostatic assembly techniques to electrospun nanofibers in order to fabricate novel, breathable electrospun fiber-based chemical and biological detoxifying protective fabrics and filters. The combination of layer-by-layer electrostatic assembly and electrospinning technique allows one to take advantage of high specific surface area, light weight and breathability of electrospun fiber mats while simultaneously providing the versatility to incorporate different functional polyelectrolytes to achieve multifunctional coatings for both chemical and biological protection together. The functionalized fiber mats can be incorporated into breathable chemical and biological protective fabrics, filters and masks. In addition, LbL electrostatic coating of porous non-woven materials provides the versatility to generate multifunctional polymer-based membrane materials for other applications. |
| FILED | Wednesday, July 21, 2010 |
| APPL NO | 12/840916 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/501 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684684 | Clements et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey Donald Clements (Mason, Ohio); Vidhu Shekhar Pandey (West Chester, Ohio); Ching-Pang Lee (Cincinnati, Ohio) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jeffrey Donald Clements (Mason, Ohio); Vidhu Shekhar Pandey (West Chester, Ohio); Ching-Pang Lee (Cincinnati, Ohio) |
| ABSTRACT | A turbine apparatus includes: A first nozzle comprising an array of first vanes each including a concave pressure side, a convex suction side, and leading and trailing edges; A rotor downstream from the first nozzle comprising a plurality of blades carried by a rotatable disk; and a second nozzle disposed downstream from the rotor comprising an array of second vanes each including a concave pressure side, a convex suction side, and leading and trailing edges; wherein the first and second vanes of the first and second nozzles are circumferentially clocked relative to each other such that, in a predetermined operating condition, wakes discharged from the first vanes are aligned in a circumferential direction with the leading edges of the second vanes, wherein a stacking axis of the first vanes is nonlinear. An inner band of the first nozzle is contoured in a non-axisymmetric shape. |
| FILED | Tuesday, August 31, 2010 |
| APPL NO | 12/872770 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684738 | Wade |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christian Patrick Wade (Stafford, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washingotn, District of Columbia) |
| INVENTOR(S) | Christian Patrick Wade (Stafford, Virginia) |
| ABSTRACT | The present invention is a firearm sight training tool, and, more specifically, relates to a method and tool for training a shooter to properly align a firearm's sights relative to a target, which through its implementation and use may provide for a more efficient and low cost means of training a firearm user to properly align a firearm's sights relative to the firearm user's target of interest. |
| FILED | Thursday, November 10, 2011 |
| APPL NO | 13/293168 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Education and demonstration 434/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685108 | Miller |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph A. Miller (Fredericksburg, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Joseph A. Miller (Fredericksburg, Virginia) |
| ABSTRACT | A modular prosthetic foot includes an ankle component; a forefoot component having a circular part with a rounded top surface and at least one flat side surface, the circular part being connected to a rear part of the forefoot component; a forefoot cushion bumper positioned around the circular part; and a heel component. |
| FILED | Tuesday, April 03, 2012 |
| APPL NO | 13/437994 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Prosthesis 623/53 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685183 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ormco Corporation (Orange, California) |
| ASSIGNEE(S) | Ormco Corporation (Orange, California) |
| INVENTOR(S) | Alfred D. Johnson (San Leandro, California); Walter A. Bachmann (Pacifica, California) |
| ABSTRACT | Metal ingots for forming single-crystal shape-memory alloys (SMAs) may be fabricated with high reliability and control by alloying thin layers of material together. In this method, a reactive layer (e.g., aluminum) is provided in thin flat layers between layers of other materials (e.g., copper and layers of nickel). When the stacked layers are vacuum heated in a crucible to the melting temperature of the reactive layer, it becomes reactive and chemically bonds to the other layers, and may form eutectics that, as the temperature is further increased, melt homogeneously and congruently at temperatures below the melting temperatures of copper and nickel. Oxidation and evaporation are greatly reduced compared to other methods of alloying, and loss of material from turbulence is minimized. |
| FILED | Tuesday, January 08, 2013 |
| APPL NO | 13/736671 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Metal treatment 148/522 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685186 | Sengupta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CFD Research Corporation (Huntsville, Alabama) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Debasis Sengupta (Madison, Alabama) |
| ABSTRACT | A group of tertiary amine azides are useful as hypergolic fuels for hypergolic bipropellant mixtures. The fuels provide higher density impulses than monomethyl hydrazine (MMH) but are less toxic and have lower vapor pressures that MMH. In addition, the fuels have shorter ignition delay times than dimethylaminoethylazide (DMAZ) and other potential reduced toxicity replacements for MMH. |
| FILED | Wednesday, January 23, 2013 |
| APPL NO | 13/748480 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685201 | O'Rourke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shawn O'Rourke (Tempe, Arizona); Douglas Loy (Chandler, Arizona); Hanqing Jiang (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Shawn O'Rourke (Tempe, Arizona); Douglas Loy (Chandler, Arizona); Hanqing Jiang (Chandler, Arizona) |
| ABSTRACT | Methods are described for addressing the bowing and/or warping of flexible substrates, attached to a rigid carrier, which occurs as a result of the thermal challenges of semiconductor processing. In particular, viscoelastic adhesives are provided which can bond a flexible substrate to a rigid carrier and mediate the thermal mismatch which often is present due to the distinctly different materials properties of most flexible substrates, such as plastic films, with respect to rigid carriers, such as silicon wafers. Assemblies are also provided which are produced according to the methods described herein. |
| FILED | Monday, April 06, 2009 |
| APPL NO | 12/921896 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685266 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emily R. Parker (Goleta, California); Brian J. Thibeault (Santa Barbara, California); Marco F. Aimi (Menands, New York); Masa P. Rao (Santa Barbara, California); Noel C. MacDonald (Santa Barbara, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Emily R. Parker (Goleta, California); Brian J. Thibeault (Santa Barbara, California); Marco F. Aimi (Menands, New York); Masa P. Rao (Santa Barbara, California); Noel C. MacDonald (Santa Barbara, California) |
| ABSTRACT | Monocyclic chlorine based inductively coupled plasma deep etching processes for the rapid micromachining of titanium substrates and titanium devices so produced are disclosed. The method parameters are adjustable to simultaneously vary etch rate, mask selectivity, and surface roughness and can be applied to titanium substrates having a wide variety of thicknesses to produce high aspect ratio features, smooth sidewalls, and smooth surfaces. The titanium microdevices so produced exhibit beneficially high fracture toughness, biocompatibility and are robust and able to withstand harsh environments making them useful in a wide variety of applications including microelectronics, micromechanical devices, MEMS, and biological devices that may be used in vivo. |
| FILED | Monday, October 02, 2006 |
| APPL NO | 11/537743 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Etching a substrate: Processes 216/67 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685273 | Aifer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Edward H Aifer (Arlington, Virginia); Sergey I Maximenko (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Edward H Aifer (Arlington, Virginia); Sergey I Maximenko (Alexandria, Virginia) |
| ABSTRACT | This disclosure involves a formula, mixing procedure, etching technique and application of an etchant for revealing defects in T2SL's grown lattice matched to (100) GaSb. The etching agent comprises a (2.5:4.5:16.5:280) solution by volume or (1%:2%:9%:88%) by weight, of HF:H2O2:H2SO4:H2O. The etchant is made by mixing (49%) hydrofluoric aqueous solution with (30%) water-based peroxide, followed by sulfuric acid, and diluted with de-ionized H2O (DI-water). |
| FILED | Tuesday, November 06, 2012 |
| APPL NO | 13/669663 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Compositions 252/79.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685286 | Svoboda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vojtech Svoboda (Huntsville, Alabama); Jianjun Wei (Huntsville, Alabama); Sameer Singhal (Huntsville, Alabama) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Vojtech Svoboda (Huntsville, Alabama); Jianjun Wei (Huntsville, Alabama); Sameer Singhal (Huntsville, Alabama) |
| ABSTRACT | The present disclosure provides an electrode including an electrically conductive ink deposited thereon comprising: a nano-scale conducting material; a binding agent; and an enzyme; wherein said ink is essentially solvent free. In one embodiment, the ink includes at least one of a mediator, a cross-linking agent and a substrate as well. In one further embodiment, the electrode provided herein is used in a battery, fuel cell or sensor. |
| FILED | Wednesday, June 08, 2011 |
| APPL NO | 13/155752 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685400 | Keane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert W. Keane (Miami, Florida); W. Dalton Dietrich (Miami, Florida); Juan Pablo De Rivero Vaccari (Miami, Florida); Helen M. Bramlett (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Robert W. Keane (Miami, Florida); W. Dalton Dietrich (Miami, Florida); Juan Pablo De Rivero Vaccari (Miami, Florida); Helen M. Bramlett (Miami, Florida) |
| ABSTRACT | Compositions and methods for reducing inflammation in the central nervous system (CNS) of a mammal that has been subjected to a stroke, traumatic injury to the CNS such as traumatic brain injury (TBI), spinal cord injury (SCI), or having an autoimmune or CNS disease have been developed. The compositions and methods described herein include antibodies that specifically bind to at least one component (e.g., ASC, NALP1) in a mammalian inflammasome (e.g., the NALP1 inflammasome) and have use as treatments for SCI, TBI, stroke, and autoimmune and CNS diseases in a mammal. In a rodent model of SCI, therapeutic neutralization of ASC using a polyclonal antibody that specifically binds to ASC inhibited the inflammasome, reduced caspase-1 activation, XIAP cleavage, and interleukin processing, resulting in significant tissue sparing and functional improvement. Additionally, in a rodent model of TBI, neutralization of ASC after TBI reduced caspase-1 activation and XIAP cleavage. Further, in a rodent thromboembolic stroke model, neutralization of NLRP1 resulted in reduced histopathological damage in mice and reduced cytokine activation, suggesting that the inflammasome complex forms in the brain after stroke and is a therapeutic target for reducing the detrimental consequences of post-stroke inflammation. |
| FILED | Wednesday, July 30, 2008 |
| APPL NO | 12/182886 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/139.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685649 | Dauner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Allison Dauner (Rockville, Maryland); Subhamoy Pal (Silver Spring, Maryland); Shuenn-Jue Wu (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Allison Dauner (Rockville, Maryland); Subhamoy Pal (Silver Spring, Maryland); Shuenn-Jue Wu (Rockville, Maryland) |
| ABSTRACT | The invention relates to a reverse transcription loop-mediated isothermal amplification (LAMP) assay for the detection of dengue virus. The assay is capable of simultaneous detection of dengue 1-4 serotypes in a single reaction. |
| FILED | Thursday, June 09, 2011 |
| APPL NO | 13/156435 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685666 | Cao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Deliang Cao (Chatham, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of Southern Illinois University (Springfield, Illinois) |
| INVENTOR(S) | Deliang Cao (Chatham, Illinois) |
| ABSTRACT | This invention provides antibodies immunologically specific for human ARL-1 (also referred to AKR1B10), a species of the aldo-keto reductase superfamily of proteins. The invention also provides methods of making and methods of using said antibodies. |
| FILED | Monday, January 31, 2011 |
| APPL NO | 13/017618 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/40.520 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685668 | Minea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Radu O. Minea (Arcadia, California); Francis S. Markland, Jr. (Manhattan Beach, California) |
| ABSTRACT | This invention relates to methods of expressing eukaryotic proteins in prokaryotic hosts, particularly eukaryotic proteins that require formation of disulfide bridges for biological activity. Various approaches are used including fusion to thioredoxin, cytoplasmic expression of disulfide isomerases, deficiencies in thioredoxin and/or glutathione reductases, deficiencies in proteases, and the like. The method is applicable to express monomeric and dimeric forms of the eukaryotic protein with biological activity such as monomeric and dimeric forms of a disintegrin or a disintegrin domain. Included are the vectors, host cells expressing the proteins, the expressed proteins and methods of using the proteins. |
| FILED | Tuesday, November 20, 2012 |
| APPL NO | 13/682470 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08685743 — Real-time, single-step bioassay using nanoplasmonic resonator with ultra-high sensitivity
| US 08685743 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ABSTRACT | A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/772118 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685841 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jiatao Zhang (Beijing, China PRC); Yun Tang (Cambridge, Massachusetts); Min Ouyang (Kensington, Maryland) |
| ASSIGNEE(S) | University of Maryland College Park (College Park, Maryland) |
| INVENTOR(S) | Jiatao Zhang (Beijing, China PRC); Yun Tang (Cambridge, Massachusetts); Min Ouyang (Kensington, Maryland) |
| ABSTRACT | The present invention is directed to a novel synthetic method for producing nanoscale heterostructures, and particularly nanoscale heterostructure particles, rods and sheets, that comprise a metal core and a monocrystalline semiconductor shell with substantial lattice mismatches between them. More specifically, the invention concerns the use of controlled soft acid-base coordination reactions between molecular complexes and colloidal nanostructures to drive the nanoscale monocrystalline growth of the semiconductor shell with a lattice structure incommensurate with that of the core. The invention also relates to more complex hybrid core-shell structures that exhibit azimuthal and radial nano-tailoring of structures. The invention is additionally directed to the use of such compositions in semiconductor devices. |
| FILED | Friday, March 23, 2012 |
| APPL NO | 13/428516 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685892 | Coates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John D. Coates (Walnut Creek, California); Mark L. Heinnickel (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | John D. Coates (Walnut Creek, California); Mark L. Heinnickel (Berkeley, California) |
| ABSTRACT | The present invention relates to methods, compositions and systems for detecting perchlorate in a sample. Compositions useful for detecting perchlorate in a sample include those comprising a perchlorate reductase, a reductant and an electron shuttle. In an exemplary embodiment, the composition comprises perchlorate reductase from Dechloromonas agitata, reduced nicotinamide adenine dinucleotide and N-methylphenazinium methylsulfate. The present invention also provides for methods of using the compositions disclosed herein, as well as systems thereof. In some exemplary embodiments, the methods comprise a concentration step, in which, for example, the sample is contacted with a cationic solid phase extraction column. Employing this step provides certain advantages such as a lowered detection limit and the removal of contaminants. |
| FILED | Tuesday, September 01, 2009 |
| APPL NO | 13/062052 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685939 | Wei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wei-Zen Wei (Grosse Pointe Farms, Michigan); Gen Sheng Wu (Troy, Michigan); Marie P. Piechocki (Fraser, Michigan); Richard F. Jones (Fayetteville, New York) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Wei-Zen Wei (Grosse Pointe Farms, Michigan); Gen Sheng Wu (Troy, Michigan); Marie P. Piechocki (Fraser, Michigan); Richard F. Jones (Fayetteville, New York) |
| ABSTRACT | The invention provides therapeutics and methods to induce a mammalian host, including a human, to produce antibodies, which agonize death receptors and cause the apoptotic death of target cells within the host's body. The therapeutics are vaccine compositions, including genetic vaccines encoding death receptor antigens of the tumor necrosis factor receptor family. Also provided are means and methods for overcoming host immunological tolerance to death receptors. The vaccines are useful against cancer cells and other death receptor bearing target cells within the host, and can be used in both therapeutic and prophylactic settings. The vaccines are also useful for diagnostic testing of the immunocompetence of a host. |
| FILED | Friday, November 06, 2009 |
| APPL NO | 13/128046 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686050 | Sadar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | British Columbia Cancer Agency Branch (Vancouver, Canada); The University of British Columbia (Vancouver, Canada) |
| ASSIGNEE(S) | The University of British Columbia (Vancouver, Canada); British Columbia Cancer Agency Branch (Vancouver, Canada) |
| INVENTOR(S) | Marianne D. Sadar (West Vancouver, Canada); Nasrin R. Mawji (Burnaby, Canada); Jun Wang (New Westminster, Canada); Raymond J. Andersen (Vancouver, Canada); David E. Williams (Vancouver, Canada); Mike Leblanc (Vancouver, Canada) |
| ABSTRACT | This invention provides compound having a structure of Formula I or Formula II Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided. |
| FILED | Friday, April 19, 2013 |
| APPL NO | 13/866933 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/721 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686054 | Elabd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yossef A. Elabd (Philadelphia, Pennsylvania); Giuseppe R. Palmese (Hainsport, New Jersey) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yossef A. Elabd (Philadelphia, Pennsylvania); Giuseppe R. Palmese (Hainsport, New Jersey) |
| ABSTRACT | A new class of membranes for use in protective clothing. More specifically, the present invention relates to a polymer-polymer membrane with an ionic polymer located within the nanopores of a porous polymer host membrane. A method for making the polymer-polymer membranes involves filling porous polymers with ionic polymers. The porous polymers may be fabricated by a template synthesis which involves sorption. The ionic polymers may be filled in the nanopores of the porous polymer by plasma-induced graft copolymerization of the ionic polymer with the porous polymeric host membrane. |
| FILED | Tuesday, April 10, 2012 |
| APPL NO | 13/443552 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686218 | Romaine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | C. Peter Romaine (State College, Pennsylvania); Carl David Schlagnhaufer (Julian, Pennsylvania); Benjamin Michael Woolston (Long Valley, New Jersey) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | C. Peter Romaine (State College, Pennsylvania); Carl David Schlagnhaufer (Julian, Pennsylvania); Benjamin Michael Woolston (Long Valley, New Jersey) |
| ABSTRACT | Disclosed is a new technology that enables the transgenic modification of a mushroom-forming fungus to confer a transgenic genotype and/or phenotype. According to the invention herein, one can manipulate the fruiting body of a fungus conferring an altered phenotype, but a wild-type genotype. The fruiting body itself is devoid of any cognate transgene, and Applicants have discovered a new mechanism of protein synthesis and accumulation in fungi and a technique to independently control the genotype and phenotype of the fruiting body. |
| FILED | Tuesday, April 12, 2011 |
| APPL NO | 13/640131 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686329 | Barry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William D. Barry (Billerica, Massachusetts); Michael J. Krueger (Bedford, New Hampshire); Amy Pietrzak (Londonderry, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | William D. Barry (Billerica, Massachusetts); Michael J. Krueger (Bedford, New Hampshire); Amy Pietrzak (Londonderry, New Hampshire) |
| ABSTRACT | A compact, purely mechanical wing deployment assisting mechanism uses torsion springs and lever arms to apply a deploying force to a guidance wing during its initial deployment through a wing slot in a rocket or missile, thereby assisting the wing to burst through a cover seal protecting the wing slot. The wings are then fully deployed by centrifugal force. Various embodiments include two “extreme duty” springs and two lever arms per wing, working in parallel. Embodiments provide a total of at least 24 pounds of force per wing at the end of a spring travel of 0.30 inches. In some embodiments, the entire mechanism weighs less than 0.5 pounds and/or occupies less than 2.5 cubic inches per wing. In embodiments, an assembled group, including two springs and two lever arms, is located between each pair of wings, whereby each assembled group applies one lever arm to each adjoining wing. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/378183 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/3.270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686351 | Ouyang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); Robert Graham Cooks (West Lafayette, Indiana); Sandilya Venkata Garimella (West Lafayette, Indiana); Jason David Harper (Lafayette, Indiana); Nicholas Alan Charipar (Batavia, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device. |
| FILED | Tuesday, July 09, 2013 |
| APPL NO | 13/937913 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686359 | Zewail |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ahmed H. Zewail (Pasadena, California) |
| ABSTRACT | The present invention relates to methods and systems for 4D ultrafast electron microscopy (UEM)—in situ imaging with ultrafast time resolution in TEM. Single electron imaging is used as a component of the 4D UEM technique to provide high spatial and temporal resolution unavailable using conventional techniques. Other embodiments of the present invention relate to methods and systems for convergent beam UEM, focusing the electron beams onto the specimen to measure structural characteristics in three dimensions as a function of time. Additionally, embodiments provide not only 4D imaging of specimens, but characterization of electron energy, performing time resolved electron energy loss spectroscopy (EELS). |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/864113 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686375 | Blick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert H. Blick (Madison, Wisconsin); Lloyd M. Smith (Madison, Wisconsin); Michael Westphall (Fichburg, Wisconsin); Hua Qin (Suzhou, China PRC) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Robert H. Blick (Madison, Wisconsin); Lloyd M. Smith (Madison, Wisconsin); Michael Westphall (Fichburg, Wisconsin); Hua Qin (Suzhou, China PRC) |
| ABSTRACT | An active detector and methods for detecting molecules, including large molecules such as proteins and oligonucleotides, at or near room temperature based on the generation of electrons via field emission (FE) and/or secondary electron emission (SEE). The detector comprises a semiconductor membrane having an external surface that is contacted by one or more molecules, and an internal surface having a thin metallic layer or other type of electron emitting layer. The kinetic energy of molecules contacting the semiconductor membrane is transferred through the membrane and induces the emission of electrons from the emitting layer. An electron detector, which optionally includes means for electron amplification, is positioned to detect the emitted electrons. |
| FILED | Monday, September 24, 2012 |
| APPL NO | 13/625731 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/397 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686576 | Smith |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexander Paul Smith (Wharton, New Jersey) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Alexander Paul Smith (Wharton, New Jersey) |
| ABSTRACT | A linear induction generator for use in a weapon system comprising a matrix of coils, a matrix of magnets, a spindle assembly, a matrix of coils, and a dust cover there over. This generator is mounted onto a weapon receiver of the weapon system to generate raw electric current. The raw current is then rectified and delivered to either a battery or directly to the electronic devices. |
| FILED | Wednesday, December 28, 2011 |
| APPL NO | 13/338548 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Prime-mover dynamo plants 290/1.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686712 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shalabh Gupta (Los Angeles, California); Bahram Jalali (Los Angeles, California); Ali Motafakker-Fard (Revere, Massachusetts) |
| ABSTRACT | A time-stretched enhanced recording scope (TiSER) is described using time stretch analog-to-digital conversion in a real-time burst mode. A chirped optical signal is modulated in response to receiving segments of an input signal. The optical signal with its modulated input signal, is stretched through an optical medium and digitized to represent the waveform segment. TiSER provides ultra-fast real-time sampling within short segment bursts of the original input signal while providing an ability to detect non-repetitive events. Methods and apparatus are also described for providing real-time information about inter-symbol information (ISI), rapidly determining bit-error rates (BER), performing time-domain reflectometry (TDR), generating eye diagrams for serial data, facilitating digital correction of data, clock recovery, optical carrier phase recovery, and otherwise increasing the speed and/or accuracy of a diverse range of high-speed signal measurement and processing activities. |
| FILED | Tuesday, April 02, 2013 |
| APPL NO | 13/855564 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/96 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686715 | Hagerty |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James D. Hagerty (Tiverton, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James D. Hagerty (Tiverton, Rhode Island) |
| ABSTRACT | The invention is a method, described with the appropriate auxiliary electronic circuitry, for compensating the effect of the earth's magnetic field on Giant Magneto-Impedance magnetic sensors. The method as taught is an alternate way of cancelling out the effect of the very large residual earth's magnetic field using an impedance-tuning circuit (i.e. electrical compensation) rather than the usual magnetic type of compensation. |
| FILED | Monday, October 31, 2011 |
| APPL NO | 13/373250 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686766 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Kanon Liu (Arcadia, California); Bryan W. Kean (Denver, Colorado); James F. Asbrock (Oceanside, California) |
| ABSTRACT | According to one embodiment, a circuit comprises a Capacitive Trans-Impedance Amplifier (CTIA) configured to receive a current pulse at an input and convert the current pulse to a voltage step. The voltage step is directed to a first signal path and a second signal path. When the voltage step exceeds a first threshold, the first signal path directs an enable pulse to the second signal path. The second signal path generates an output pulse when the voltage step exceeds a second threshold and the enable pulse is enabled. The second signal path comprises a first, a second, and a third amplifier to increase detection of the voltage step by the second signal path. |
| FILED | Monday, February 11, 2013 |
| APPL NO | 13/764483 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/142 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686892 | McCleary |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brent McCleary (Chino Hills, California) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Brent McCleary (Chino Hills, California) |
| ABSTRACT | A method of reducing cross-range streaking in a radar image includes determining a number of on-pixels in each line of at least a portion of the radar image, determining which lines have a determined number of on-pixels that exceeds a threshold number, and removing the on-pixels of lines having the determined number of on-pixels exceeding the threshold number. |
| FILED | Friday, August 05, 2011 |
| APPL NO | 13/204497 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/25.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686896 | Schuman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Harvey K. Schuman (Cazenovia, New York); Anthony M. Davis (Milwaukee, Wisconsin); Donald M. McPherson (Pompey, New York); Michael Robinson (Drexel Hill, Pennsylvania); David R. Hagenmayer (Liverpool, New York); John G. Wiley (Marietta, New York) |
| ASSIGNEE(S) | SRC, Inc. (North Syracuse, New York) |
| INVENTOR(S) | Harvey K. Schuman (Cazenovia, New York); Anthony M. Davis (Milwaukee, Wisconsin); Donald M. McPherson (Pompey, New York); Michael Robinson (Drexel Hill, Pennsylvania); David R. Hagenmayer (Liverpool, New York); John G. Wiley (Marietta, New York) |
| ABSTRACT | A method for determining beamformer scattering parameters for a plurality of phased array radar antenna subarrays that each include a radiating (e.g., dipole) component and a beamformer component provides for obtaining for the plurality of phased array radar antenna subarrays a plurality of electromagnetic measurements at a plurality of ports. Analogous electromagnetic measurements are obtained for a reference subarray including a radiating component but absent a beamformer component. The plurality of phased array radar antenna subarray electromagnetic measurements and the reference subarray electromagnetic measurements provide a plurality of beamformer scattering parameter values for the plurality of phased array radar antenna subarrays that may be used in modeling and calibrating a phased array radar apparatus that may be assembled from the plurality of phased array radar antenna subarrays. |
| FILED | Friday, February 11, 2011 |
| APPL NO | 13/025652 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686920 | Sarabandi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kamal Sarabandi (Ann Arbor, Michigan); Young Jun Song (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Kamal Sarabandi (Ann Arbor, Michigan); Young Jun Song (Ann Arbor, Michigan) |
| ABSTRACT | A radio repeater system is provided that utilizes miniaturized antennas and a meta-material channel isolator. The radio repeater is comprised of: a receive antenna configured to receive a signal at a desired channel frequency; a transmit antenna configured to transmit the signal at the channel frequency; an amplifier electrically connected between the receive antenna and the transmit antenna; and an array of resonating circuits disposed spatially between the receive antenna and the transmit antenna. Each resonating circuit is designed to resonant at the channel frequency and thereby suppress propagation of surface waves between the antennas. |
| FILED | Wednesday, May 25, 2011 |
| APPL NO | 13/115377 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/893 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687111 | McKaughan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen V. McKaughan (Arlington, Massachusetts); Philip A. Rombult (Boxford, Massachusetts); Robert J. Campbell, Jr. (Manchester, New Hampshire) |
| ASSIGNEE(S) | FLIR Systems, Inc. (Wilsonville, Oregon) |
| INVENTOR(S) | Stephen V. McKaughan (Arlington, Massachusetts); Philip A. Rombult (Boxford, Massachusetts); Robert J. Campbell, Jr. (Manchester, New Hampshire) |
| ABSTRACT | A compact optical payload for an unmanned aircraft includes two infrared cameras for wide and narrow field viewing, a daylight color camera, a laser pointer and a laser range finder. |
| FILED | Monday, May 11, 2009 |
| APPL NO | 12/463858 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Television 348/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687333 | Gosse |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James A. Gosse (Storrs, Connecticut) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| INVENTOR(S) | James A. Gosse (Storrs, Connecticut) |
| ABSTRACT | An overcurrent protection circuit for a high side solenoid switch includes a primary bias circuit and a secondary bias circuit. The secondary bias circuit is operable to alter a source to gate bias voltage of the high side solenoid switch during an overcurrent. |
| FILED | Thursday, June 16, 2011 |
| APPL NO | 13/161567 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/87 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687689 | Baraniuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard Baraniuk (Houston, Texas); Dror Z. Baron (Houston, Texas); Marco F. Duarte (Houston, Texas); Mohamed Elnozahi (Houston, Texas); Michael B. Wakin (Ann Arbor, Michigan); Mark A. Davenport (Houston, Texas); Jason N. Laska (Houston, Texas); Joel A. Tropp (Ann Arbor, Michigan); Yehia Massoud (Houston, Texas); Sami Kirolos (Houston, Texas); Tamer Ragheb (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard Baraniuk (Houston, Texas); Dror Z. Baron (Houston, Texas); Marco F. Duarte (Houston, Texas); Mohamed Elnozahi (Houston, Texas); Michael B. Wakin (Ann Arbor, Michigan); Mark A. Davenport (Houston, Texas); Jason N. Laska (Houston, Texas); Joel A. Tropp (Ann Arbor, Michigan); Yehia Massoud (Houston, Texas); Sami Kirolos (Houston, Texas); Tamer Ragheb (Houston, Texas) |
| ABSTRACT | A typical data acquisition system takes periodic samples of a signal, image, or other data, often at the so-called Nyquist/Shannon sampling rate of two times the data bandwidth in order to ensure that no information is lost. In applications involving wideband signals, the Nyquist/Shannon sampling rate is very high, even though the signals may have a simple underlying structure. Recent developments in mathematics and signal processing have uncovered a solution to this Nyquist/Shannon sampling rate bottlenck for signals that are sparse or compressible in some representation. We demonstrate and reduce to practice methods to extract information directly from an analog or digital signal based on altering our notion of sampling to replace uniform time samples with more general linear functionals. One embodiment of our invention is a low-rate analog-to-information converter that can replace the high-rate analog-to-digital converter in certain applications involving wideband signals. Another embodiment is an encoding scheme for wideband discrete-time signals that condenses their information content. |
| FILED | Wednesday, October 25, 2006 |
| APPL NO | 12/091340 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Pulse or digital communications 375/240.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687849 | Haanpaa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Douglas Haanpaa (Dexter, Michigan); Charles J. Cohen (Ann Arbor, Michigan); Glenn J. Beach (Brooklyn, Michigan); Charles J. Jacobus (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Cybernet Systems Corporation (Ann Arbor, Michigan) |
| INVENTOR(S) | Douglas Haanpaa (Dexter, Michigan); Charles J. Cohen (Ann Arbor, Michigan); Glenn J. Beach (Brooklyn, Michigan); Charles J. Jacobus (Ann Arbor, Michigan) |
| ABSTRACT | A system for performing object identification combines pose determination, EO/IR sensor data, and novel computer graphics rendering techniques. A first module extracts the orientation and distance of a target in a truth chip given that the target type is known. A second module identifies the vehicle within a truth chip given the known distance and elevation angle from camera to target. Image matching is based on synthetic image and truth chip image comparison, where the synthetic image is rotated and moved through a 3-Dimensional space. It is assumed that the object is positioned on relatively flat ground and that the camera roll angle stays near zero. This leaves three dimensions of motion (distance, heading, and pitch angle) to define the space in which the synthetic target is moved. A graphical user interface (GUI) front end allows the user to manually adjust the orientation of the target within the synthetic images. |
| FILED | Tuesday, April 03, 2012 |
| APPL NO | 13/438397 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688036 | Parkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John W. Parkins (Ithaca, New York); Mike Bartos (Groton, New York) |
| ASSIGNEE(S) | Red Tail Hawk Corporation (Ithaca, New York) |
| INVENTOR(S) | John W. Parkins (Ithaca, New York); Mike Bartos (Groton, New York) |
| ABSTRACT | A wireless communications headset system for double hearing protection systems that eliminates the problems associated with typical wireless communications systems. The system employs a magnetic-field coupled wireless link from a loop transmitter to a magnetic field receiver. Current through the transmitter wire loops generates magnetic flux which passes through a communications earplug. The earplug has a receiver for converting the magnetic flux to electrical voltage, and this voltage is used to drive a speaker within the earplug. The transmitter can be easily installed into aviation headsets. The loop transmitter has an open center sized so that it fits around the pinna of the human ear enabling a close position to the communications earplug. This close position is advantageous if an efficient system is desired. |
| FILED | Friday, August 10, 2007 |
| APPL NO | 11/837129 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/41.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688427 | Baker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Baker (Seattle, Washington); Alexandre Zangellini (Seattle, Washington); Justin Siegel (Seattle, Washington); Jennifer St. Clair (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | David Baker (Seattle, Washington); Alexandre Zangellini (Seattle, Washington); Justin Siegel (Seattle, Washington); Jennifer St. Clair (Seattle, Washington) |
| ABSTRACT | The present invention provides enzyme catalysts for Diels-Alder reactions, including intermolecular Diels-Alder reactions, as well as protein scaffolds for making such enzyme catalysts. In other aspects, the invention provides methods of making the enzyme catalysts, including by de novo computational design. The present invention thereby provides enzyme catalysts capable of catalyzing a desired Diels-Alder reaction, including with a specified or desired stereo-selectivity. |
| FILED | Thursday, November 19, 2009 |
| APPL NO | 13/130260 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688619 | Ezick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Ezick (Canonsburg, Pennsylvania); Richard Lethin (New York, New York); Nicolas Vasilache (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs (New York, New York) |
| INVENTOR(S) | James Ezick (Canonsburg, Pennsylvania); Richard Lethin (New York, New York); Nicolas Vasilache (New York, New York) |
| ABSTRACT | Methods, apparatus, and computer software product for making a decision based on the semantics of formal logic are provided. In an exemplary embodiment, two custom computing apparatuses are used to resolve the satisfiability of a logical formula and provide an example. In this embodiment, the two custom computing apparatuses operate in concert to explore the space of possible satisfying examples. This Abstract is provided for the sole purpose of complying with the Abstract requirement rules. This Abstract is submitted with the explicit understanding that it will not be used to interpret or to limit the scope or the meaning of the claims. |
| FILED | Monday, March 08, 2010 |
| APPL NO | 12/719750 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688759 | Mody |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Apurva N. Mody (Lowell, Massachusetts) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Apurva N. Mody (Lowell, Massachusetts) |
| ABSTRACT | An algorithm system to detect a broad class of signals in Gaussian noise using higher-order statistics. The algorithm system detects a number of different signal types. The signals may be in the base-band or the pass-band, single-carrier or multi-carrier, frequency hopping or non-hopping, broad-pulse or narrow-pulse etc. In a typical setting this algorithm system provides an error rate of 3/100 at a signal to noise ratio of 0 dB. This algorithm system gives the time frequency detection ratio that may be used to determine if the detected signal falls in Class Single-Carrier of Class Multi-Carrier. Additionally this algorithm system may be used for a number of different applications such as multiple signal identification, finding the basis functions of the received signal and the like. |
| FILED | Tuesday, December 22, 2009 |
| APPL NO | 12/644513 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/404 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688769 | Atkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Mark G. Atkins (Arvada, Colorado); James E. Carey (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota) |
| ABSTRACT | Methods, apparatuses, and computer program products for selected alert delivery in a distributed processing system are provided. Embodiments include receiving a plurality of events from one or more event producing components of the distributed processing system; creating, by an incident analyzer, in dependence upon the events a truth space representing events that make one or more conditional event processing rules true, the truth space including a set of truth points, each truth point including a set of events and a set of event locations; creating, by the incident analyzer, in dependence upon the truth space one or more alerts including assigning one of the locations of the truth space to one or more of the alerts; and sending, by the incident analyzer, the alerts to at least one component of the distributed processing system. |
| FILED | Thursday, January 10, 2013 |
| APPL NO | 13/738043 |
| ART UNIT | 2447 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/201 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688791 | Sheth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amit Sheth (Dayton, Ohio); Karthik Gomadam (San Jose, California); Meenakshi Nagarajan (San Jose, California) |
| ASSIGNEE(S) | Wright State University (Dayton, Ohio) |
| INVENTOR(S) | Amit Sheth (Dayton, Ohio); Karthik Gomadam (San Jose, California); Meenakshi Nagarajan (San Jose, California) |
| ABSTRACT | The present invention generally relates to methods and systems for analysis of real-time user-generated text messages. The methods and systems allow analysis to be performed using term associations and geographical and temporal constraints. |
| FILED | Wednesday, February 16, 2011 |
| APPL NO | 13/028397 |
| ART UNIT | 2479 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688795 | Hill |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David T. Hill (Bedford, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David T. Hill (Bedford, Indiana) |
| ABSTRACT | A computer implemented system for generating an output message stream from multiple input streams in which particular messages are prioritized. |
| FILED | Tuesday, May 31, 2011 |
| APPL NO | 13/149853 |
| ART UNIT | 2413 — Multiplex and VoIP |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/207 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688833 | Nishimoto |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daron L. Nishimoto (Kihei, Hawaii) |
| ASSIGNEE(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Daron L. Nishimoto (Kihei, Hawaii) |
| ABSTRACT | A worldwide network of Autonomous Robotic Telescope Systems (ARTS) tracks and analyzes space objects (satellites, shuttle, space debris, etc.) and astronomical objects (asteroids, comets, supernovas, etc.), and includes the ability to automatically schedule observations using remote, programmable or Internet controllable information networks. The system works with commercial off-the-shelf (COTS) items that include telescopes, mounts, cameras (e.g. CCD), software and computers. The telescope systems operate autonomously and remotely over Internet lines. Automatic scheduling is achieved by programming the slave telescope control computer. Satellite propagators and two line elements necessary for satellite tracking are provided on several Internet sites. Strategically placing these small portable telescope systems around the world enables users to acquire worldwide space object coverage and to be geographically diverse. This is also a cost effective way to provide necessary data to users. |
| FILED | Friday, November 08, 2002 |
| APPL NO | 10/290527 |
| ART UNIT | 2442 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/225 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688850 | Branson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Zhen Liu (Tarrytown, New York); Fan Ye (Ossining, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Zhen Liu (Tarrytown, New York); Fan Ye (Ossining, New York) |
| ABSTRACT | A cooperative data stream processing system is provided that utilizes a plurality of independent, autonomous and potentially heterogeneous sites in a cooperative arrangement to process user-defined inquiries over dynamic, continuous streams of data. The system derives jobs from the inquiries and these jobs are executed on the various distributed sites by executing applications containing processing elements on these sites. Therefore, components of a given job can be executed simultaneously and in parallel on a plurality of sites within in the system. The sites associated with a given job execution have the need to share data, both primal and derived. A tunnel mechanism is provided that establishes tunnels between pairs of sites within the system. Each tunnel includes either a sink processing element on an originating site and a source processing element on a destination site or a gateway processing element on each site and a network connection between the sink and source processing elements. The sink and source processing elements are in communication with application processing elements on their respective sites and facilitate the exchange of data between these application processing elements. Tunnels can be establish on demand or in accordance with a prescribed plan and can be job specific of generic to any job executing on a given pair of sites. |
| FILED | Friday, May 11, 2007 |
| APPL NO | 11/747694 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08689050 | Carey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | James E. Carey (Rochester, Minnesota); Matthew W. Markland (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota) |
| ABSTRACT | Restarting event and alert analysis after a shutdown in a distributed processing system includes identifying a shutdown condition of the distributed processing system; and determining whether the shutdown was a planned shutdown or an unplanned shutdown; if the shutdown was planned, storing an identification of the last event in an event log that was injected in an event queue at the time of the planned shutdown and restarting event and alert analysis using the next event identified in the event log; if the shutdown was unplanned, identifying a previously configured restart mode; selecting an identification of a restart event in the event log according to the previously configured restart mode; and restarting event and alert analysis using the restart event identified in the event log. |
| FILED | Thursday, November 08, 2012 |
| APPL NO | 13/672044 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08683801 | Ernst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy C. Ernst (Columbus, Indiana); Christopher R. Nelson (Columbus, Indiana); James A. Zigan (Versailles, Indiana) |
| ASSIGNEE(S) | Cummins Intellectual Properties, Inc. (Minneapolis, Minnesota) |
| INVENTOR(S) | Timothy C. Ernst (Columbus, Indiana); Christopher R. Nelson (Columbus, Indiana); James A. Zigan (Versailles, Indiana) |
| ABSTRACT | The disclosure provides a waste heat recovery system and method in which pressure in a Rankine cycle (RC) system of the WHR system is regulated by diverting working fluid from entering an inlet of an energy conversion device of the RC system. In the system, an inlet of a controllable bypass valve is fluidly coupled to a working fluid path upstream of an energy conversion device of the RC system, and an outlet of the bypass valve is fluidly coupled to the working fluid path upstream of the condenser of the RC system such that working fluid passing through the bypass valve bypasses the energy conversion device and increases the pressure in a condenser. A controller determines the temperature and pressure of the working fluid and controls the bypass valve to regulate pressure in the condenser. |
| FILED | Saturday, August 13, 2011 |
| APPL NO | 13/209398 |
| ART UNIT | 3748 — Static Structures, Supports and Furniture |
| CURRENT CPC | Power plants 060/615 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684040 | Bernitsas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael M. Bernitsas (Saline, Michigan); Kamaldev Raghavan (Houston, Texas) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Michael M. Bernitsas (Saline, Michigan); Kamaldev Raghavan (Houston, Texas) |
| ABSTRACT | Roughness is added to the surface of a bluff body in a relative motion with respect to a fluid. The amount, size, and distribution of roughness on the body surface is controlled passively or actively to modify the flow around the body and subsequently the Vortex Induced Forces and Motion (VIFM). The added roughness, when designed and implemented appropriately, affects in a predetermined way the boundary layer, the separation of the boundary layer, the level of turbulence, the wake, the drag and lift forces, and consequently the Vortex Induced Motion (VIM), and the fluid-structure interaction. The goal of surface roughness control is to decrease/suppress Vortex Induced Forces and Motion. Suppression is required when fluid-structure interaction becomes destructive as in VIM of flexible cylinders or rigid cylinders on elastic support, such as underwater pipelines, marine risers, tubes in heat exchangers, nuclear fuel rods, cooling towers, SPAR offshore platforms. |
| FILED | Thursday, May 22, 2008 |
| APPL NO | 12/125409 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/808 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684187 | Buschmann |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne E. Buschmann (Boulder, Colorado) |
| ASSIGNEE(S) | Eltron Research and Development, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Wayne E. Buschmann (Boulder, Colorado) |
| ABSTRACT | A polyamide membrane including reaction product of an anhydrous solution comprising an anhydrous solvent, at least one polyfunctional secondary amine and a pre-polymer deposition catalyst, and an anhydrous, organic solvent solution comprising a polyfunctional aromatic amine-reactive reactant having one ring. A composite semipermeable membrane including the polyamide membrane on a porous support. |
| FILED | Monday, March 05, 2012 |
| APPL NO | 13/412538 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/500.380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684592 | Miller, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Algenol Biofuels Inc. (Bonita Springs, Florida) |
| ASSIGNEE(S) | Algenol Biofuels Inc. (Fort Myers, Florida) |
| INVENTOR(S) | Harlan Miller, III (Fort Myers, Florida); George Meichel (Fort Myers, Florida); Edward Legere (Lake Worth, Florida); Edwin Malkiel (Naples, Florida); Robert Paul Woods (Naples, Florida); Oliver Ashley (Fort Myers, Florida); Joseph Katz (Baltimore, Maryland); Jason Ward (Fort Myers, Florida); Paul Petersen (West Palm Beach, Florida) |
| ABSTRACT | The invention provides a mixing system comprising a magnetically coupled drive system and a foil for cultivating algae, or cyanobacteria, in an open or enclosed vessel. The invention provides effective mixing, low energy usage, low capital expenditure, and ease of drive system component maintenance while maintaining the integrity of a sealed mixing vessel. |
| FILED | Tuesday, February 12, 2013 |
| APPL NO | 13/765580 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Agitating 366/273 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684666 | Marra |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John J. Marra (Winter Springs, Florida) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | John J. Marra (Winter Springs, Florida) |
| ABSTRACT | A low pressure cooling system for a turbine engine for directing cooling fluids at low pressure, such as at ambient pressure, through at least one cooling fluid supply channel and into a cooling fluid mixing chamber positioned immediately downstream from a row of turbine blades extending radially outward from a rotor assembly to prevent ingestion of hot gases into internal aspects of the rotor assembly. The low pressure cooling system may also include at least one bleed channel that may extend through the rotor assembly and exhaust cooling fluids into the cooling fluid mixing chamber to seal a gap between rotational turbine blades and a downstream, stationary turbine component. Use of ambient pressure cooling fluids by the low pressure cooling system results in tremendous efficiencies by eliminating the need for pressurized cooling fluids for sealing this gap. |
| FILED | Tuesday, April 12, 2011 |
| APPL NO | 13/084618 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684668 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Russell B Jones (North Palm Beach, Florida); Judson J Krueger (Jupiter, Florida); William L Plank (Tequesta, Florida) |
| ASSIGNEE(S) | Florida Turbine Technologies, Inc. (Jupiter, Florida) |
| INVENTOR(S) | Russell B Jones (North Palm Beach, Florida); Judson J Krueger (Jupiter, Florida); William L Plank (Tequesta, Florida) |
| ABSTRACT | A sequential impingement cooling insert for a turbine stator vane that forms a double impingement for the pressure and suction sides of the vane or a triple impingement. The insert is formed from a sheet metal formed in a zigzag shape that forms a series of alternating impingement cooling channels with return air channels, where pressure side and suction side impingement cooling plates are secured over the zigzag shaped main piece. Another embodiment includes the insert formed from one or two blocks of material in which the impingement channels and return air channels are machined into each block. |
| FILED | Monday, November 26, 2012 |
| APPL NO | 13/685053 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684673 | Salazar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Santiago Salazar (Orlando, Florida); Andrew Gisch (Annandale, Virginia) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | Santiago Salazar (Orlando, Florida); Andrew Gisch (Annandale, Virginia) |
| ABSTRACT | A seal structure for a gas turbine engine, the seal structure including first and second components located adjacent to each other and forming a barrier between high and low pressure zones. A seal cavity is defined in the first and second components, the seal cavity extending to either side of an elongated gap extending generally in a first direction between the first and second components. A seal member is positioned within the seal cavity and spans across the elongated gap. The seal member includes first and second side edges extending into each of the components in a second direction transverse to the first direction, and opposing longitudinal edges extending between the side edges generally parallel to the first direction. The side edges include a groove formed therein for effecting a reduction of gas flow around the seal member at the side edges. |
| FILED | Wednesday, June 02, 2010 |
| APPL NO | 12/791968 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/139 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08684692 | Mayer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clinton A. Mayer (Tequesta, Florida); Christian X. Campbell (Oviedo, Florida); Andrew Whalley (Jupiter, Florida); John J. Marra (Winter Springs, Florida) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | Clinton A. Mayer (Tequesta, Florida); Christian X. Campbell (Oviedo, Florida); Andrew Whalley (Jupiter, Florida); John J. Marra (Winter Springs, Florida) |
| ABSTRACT | A turbine blade assembly in a turbine engine. The turbine blade assembly includes a turbine blade and a first snubber structure. The turbine blade includes an internal cooling passage containing cooling air. The first snubber structure extends outwardly from a sidewall of the turbine blade and includes a hollow interior portion that receives cooling air from the internal cooling passage of the turbine blade. |
| FILED | Wednesday, February 09, 2011 |
| APPL NO | 13/023651 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/97.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685000 | Buckley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Patrick R. Buckley (New York, New York); Duncan J. Maitland (Pleasant Hill, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Patrick R. Buckley (New York, New York); Duncan J. Maitland (Pleasant Hill, California) |
| ABSTRACT | A shape memory material with integrated actuation using embedded particles. One embodiment provides a shape memory material apparatus comprising a shape memory material body and magnetic pieces in the shape memory material body. Another embodiment provides a method of actuating a device to perform an activity on a subject comprising the steps of positioning a shape memory material body in a desired position with regard to the subject, the shape memory material body capable of being formed in a specific primary shape, reformed into a secondary stable shape, and controllably actuated to recover the specific primary shape; including pieces in the shape memory material body; and actuating the shape memory material body using the pieces causing the shape memory material body to be controllably actuated to recover the specific primary shape and perform the activity on the subject. |
| FILED | Monday, April 30, 2012 |
| APPL NO | 13/460596 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/530 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685118 | Murphy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy A. Murphy (Derby, Kansas); Michael J. Tupy (Crystal, Minnesota); Timothy W. Abraham (Minnetonka, Minnesota); Andy Shafer (Minnetonka, Minnesota) |
| ASSIGNEE(S) | Elevance Renewable Sciences, Inc. (Bolingbrook, Illinois) |
| INVENTOR(S) | Timothy A. Murphy (Derby, Kansas); Michael J. Tupy (Crystal, Minnesota); Timothy W. Abraham (Minnetonka, Minnesota); Andy Shafer (Minnetonka, Minnesota) |
| ABSTRACT | A wax comprises a metathesis product and/or a product that resembles, at least in part, a product which may be formed from a metathesis reaction. The wax may be used to form articles, for example, candles (container candles, votive candles, and/or a pillar candles), crayons, fire logs, or tarts. The wax commonly includes other components in addition to the metathesis product. |
| FILED | Tuesday, January 10, 2006 |
| APPL NO | 11/795052 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fuel and related compositions 044/308 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685162 | Kellerman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter L. Kellerman (Essex, Massachusetts); Gregory D. Thronson (Groveland, Massachusetts); Dawei Sun (Nashua, New Hampshire) |
| ASSIGNEE(S) | Varian Semiconductor Equipment Associates, Inc. (Gloucester, Massachusetts) |
| INVENTOR(S) | Peter L. Kellerman (Essex, Massachusetts); Gregory D. Thronson (Groveland, Massachusetts); Dawei Sun (Nashua, New Hampshire) |
| ABSTRACT | In one embodiment, a sheet production apparatus comprises a vessel configured to hold a melt of a material. A cooling plate is disposed proximate the melt and is configured to form a sheet of the material on the melt. A first gas jet is configured to direct a gas toward an edge of the vessel. A sheet of a material is translated horizontally on a surface of the melt and the sheet is removed from the melt. The first gas jet may be directed at the meniscus and may stabilize this meniscus or increase local pressure within the meniscus. |
| FILED | Tuesday, March 01, 2011 |
| APPL NO | 13/037789 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 9/00 (20130101) Original (OR) Class C30B 15/00 (20130101) C30B 15/002 (20130101) C30B 15/06 (20130101) C30B 15/22 (20130101) C30B 15/24 (20130101) C30B 15/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685281 | Bingham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dennis N. Bingham (Idaho Falls, Idaho); Kerry M. Kllingler (Idaho Falls, Idaho); Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Bradley C. Benefiel (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Dennis N. Bingham (Idaho Falls, Idaho); Kerry M. Kllingler (Idaho Falls, Idaho); Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Bradley C. Benefiel (Idaho Falls, Idaho) |
| ABSTRACT | The production of gasses and, more particularly, to systems and methods for the production of syngas and fuel gasses including the production of hydrogen are set forth. In one embodiment system and method includes a reactor having a molten pool of a material comprising sodium carbonate. A supply of conditioned water is in communication with the reactor. A supply of carbon containing material is also in communication with the reactor. In one particular embodiment, the carbon containing material may include vacuum residuum (VR). The water and VR may be kept at desired temperatures and pressures compatible with the process that is to take place in the reactor. When introduced into the reactor, the water, the VR and the molten pool may be homogenously mixed in an environment in which chemical reactions take place including the production of hydrogen and other gasses. |
| FILED | Thursday, July 21, 2011 |
| APPL NO | 13/188167 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compositions 252/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685287 | Worsley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marcus A. Worsley (Hayward, California); Theodore F. Baumann (Discovery Bay, California); Joe H. Satcher, Jr. (Patterson, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Marcus A. Worsley (Hayward, California); Theodore F. Baumann (Discovery Bay, California); Joe H. Satcher, Jr. (Patterson, California) |
| ABSTRACT | A method of making a mechanically robust, electrically conductive ultralow-density carbon nanotube-based aerogel, including the steps of dispersing nanotubes in an aqueous media or other media to form a suspension, adding reactants and catalyst to the suspension to create a reaction mixture, curing the reaction mixture to form a wet gel, drying the wet gel to produce a dry gel, and pyrolyzing the dry gel to produce the mechanically robust, electrically conductive ultralow-density carbon nanotube-based aerogel. The aerogel is mechanically robust, electrically conductive, and ultralow-density, and is made of a porous carbon material having 5 to 95% by weight carbon nanotubes and 5 to 95% carbon binder. |
| FILED | Tuesday, January 05, 2010 |
| APPL NO | 12/652616 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/510 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685364 | Davis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Benjamin L. Davis (Los Alamos, New Mexico); Brian D. Rekken (Los Alamos, New Mexico) |
| ABSTRACT | Liquid compositions of ammonia borane and a suitably chosen amine borane material were prepared and subjected to conditions suitable for their thermal decomposition in a closed system that resulted in hydrogen and a liquid reaction product. |
| FILED | Tuesday, March 26, 2013 |
| APPL NO | 13/850959 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/648.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685549 | Goyal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amit Goyal (Knoxville, Tennessee); Junsoo Shin (Brentwood, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Amit Goyal (Knoxville, Tennessee); Junsoo Shin (Brentwood, Tennessee) |
| ABSTRACT | A nanocomposite article that includes a single-crystal or single-crystal-like substrate and heteroepitaxial, phase-separated layer supported by a surface of the substrate and a method of making the same are described. The heteroepitaxial layer can include a continuous, non-magnetic, crystalline, matrix phase, and an ordered, magnetic magnetic phase disposed within the matrix phase. The ordered magnetic phase can include a plurality of self-assembled crystalline nanostructures of a magnetic material. The phase-separated layer and the single crystal substrate can be separated by a buffer layer. An electronic storage device that includes a read-write head and a nanocomposite article with a data storage density of 0.75 Tb/in2 is also described. |
| FILED | Tuesday, November 30, 2010 |
| APPL NO | 12/956598 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Stock material or miscellaneous articles 428/846.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685599 | Adams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David P. Adams (Albuquerque, New Mexico); Joel Patrick McDonald (Midland, Michigan); Bradley Howell Jared (Albuquerque, New Mexico); V. Carter Hodges (Albuquerque, New Mexico); Deidre Hirschfeld (Socorro, New Mexico); Dianna S. Blair (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | David P. Adams (Albuquerque, New Mexico); Joel Patrick McDonald (Midland, Michigan); Bradley Howell Jared (Albuquerque, New Mexico); V. Carter Hodges (Albuquerque, New Mexico); Deidre Hirschfeld (Socorro, New Mexico); Dianna S. Blair (Albuquerque, New Mexico) |
| ABSTRACT | A method of pulsed laser intrinsic marking can provide a unique identifier to detect tampering or counterfeiting. |
| FILED | Thursday, February 23, 2012 |
| APPL NO | 13/403117 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685667 | Waldo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Geoffrey S. Waldo (Santa Fe, New Mexico); Stephanie Cabantous (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Geoffrey S. Waldo (Santa Fe, New Mexico); Stephanie Cabantous (Los Alamos, New Mexico) |
| ABSTRACT | The invention provides a protein labeling and detection system based on self-complementing fragments of fluorescent and chromophoric proteins. The system of the invention is exemplified with various combinations of self-complementing fragments derived from Aequorea victoria Green Fluorescent Protein (GFP), which are used to detect and quantify protein solubility in multiple assay formats, both in vitro and in vivo. |
| FILED | Friday, May 27, 2011 |
| APPL NO | 13/118174 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685685 | Retsina et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | API Intellectual Property Holdings, LLC (Atlanta, Georgia) |
| ASSIGNEE(S) | API Intellectual Property Holdings, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Theodora Retsina (Altanta, Georgia); Vesa Pylkkanen (Atlanta, Georgia) |
| ABSTRACT | This invention provides processes and apparatus to convert biomass, including wood and agricultural residues, into low-ash biomass pellets for combustion, alone or in combination with another solid fuel. Some embodiments provide processes for producing hemicellulosic sugars and low-ash biomass from cellulosic biomass, comprising providing an aqueous extraction solution with acetic acid; extracting the feedstock to produce an extract liquor containing soluble ash, hemicellulosic oligomers, acetic acid, dissolved lignin, and cellulose-rich solids; dewatering and drying the cellulose-rich, lignin-rich solids to produce a low-ash biomass; hydrolyzing the hemicellulosic oligomers to produce fermentable hemicellulosic sugars, wherein additional acetic acid is generated; removing a vapor stream comprising vaporized acetic acid from the extract; recycling the vapor or its condensate to provide some starting acetic acid for the extraction solution; and recovering fermentable hemicellulosic sugars. The disclosed processes can produce clean power from biomass. Co-products include fermentation products such as ethanol, fertilizers, and lignin. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 13/829237 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/165 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08685743 — Real-time, single-step bioassay using nanoplasmonic resonator with ultra-high sensitivity
| US 08685743 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ABSTRACT | A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/772118 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685767 | Tansu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nelson Tansu (Bethlehem, Pennsylvania); Hongping Zhao (Bethlehem, Pennsylvania); Jing Zhang (Bethlehem, Pennsylvania); Guangyu Liu (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Nelson Tansu (Bethlehem, Pennsylvania); Hongping Zhao (Bethlehem, Pennsylvania); Jing Zhang (Bethlehem, Pennsylvania); Guangyu Liu (Bethlehem, Pennsylvania) |
| ABSTRACT | A double-metallic deposition process is used whereby adjacent layers of different metals are deposited on a substrate. The surface plasmon frequency of a base layer of a first metal is tuned by the surface plasmon frequency of a second layer of a second metal formed thereon. The amount of tuning is dependent upon the thickness of the metallic layers, and thus tuning can be achieved by varying the thicknesses of one or both of the metallic layers. In a preferred embodiment directed to enhanced LED technology in the green spectrum regime, a double-metallic Au/Ag layer comprising a base layer of gold (Au) followed by a second layer of silver (Ag) formed thereon is deposited on top of InGaN/GaN quantum wells (QWs) on a sapphire/GaN substrate. |
| FILED | Wednesday, December 08, 2010 |
| APPL NO | 12/963117 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685781 | Semonin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Octavi Escala Semonin (Eugene, Oregon); Joseph M. Luther (Boulder, Colorado); Matthew C. Beard (Arvada, Colorado); Hsiang-Yu Chen (Chungli, China PRC) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Octavi Escala Semonin (Eugene, Oregon); Joseph M. Luther (Boulder, Colorado); Matthew C. Beard (Arvada, Colorado); Hsiang-Yu Chen (Chungli, China PRC) |
| ABSTRACT | A method of forming an optoelectronic device. The method includes providing a deposition surface and contacting the deposition surface with a ligand exchange chemical and contacting the deposition surface with a quantum dot (QD) colloid. This initial process is repeated over one or more cycles to form an initial QD film on the deposition surface. The method further includes subsequently contacting the QD film with a secondary treatment chemical and optionally contacting the surface with additional QDs to form an enhanced QD layer exhibiting multiple exciton generation (MEG) upon absorption of high energy photons by the QD active layer. Devices having an enhanced QD active layer as described above are also disclosed. |
| FILED | Wednesday, July 20, 2011 |
| APPL NO | 13/187276 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/82 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685878 | Stamenkovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vojislav Stamenkovic (Naperville, Illinois); Nenad M. Markovic (Hinsdale, Illinois); Chao Wang (Chicago, Illinois); Hideo Daimon (Osaka, Japan); Shouheng Sun (Providence, Rhode Island) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Vojislav Stamenkovic (Naperville, Illinois); Nenad M. Markovic (Hinsdale, Illinois); Chao Wang (Chicago, Illinois); Hideo Daimon (Osaka, Japan); Shouheng Sun (Providence, Rhode Island) |
| ABSTRACT | A multimetallic nanoscale catalyst having a core portion enveloped by a shell portion and exhibiting high catalytic activity and improved catalytic durability. In various embodiments, the core/shell nanoparticles comprise a gold particle coated with a catalytically active platinum bimetallic material. The shape of the nanoparticles is substantially defined by the particle shape of the core portion. The nanoparticles may be dispersed on a high surface area substrate for use as a catalyst and is characterized by no significant loss in surface area and specific activity following extended potential cycling. |
| FILED | Monday, April 23, 2012 |
| APPL NO | 13/453782 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686083 | Garn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Troy G. Garn (Idaho Falls, Idaho); Jack D. Law (Pocatello, Idaho); Mitchell R. Greenhalgh (Iona, Idaho); Rhonda Tranter (Mena, Arizona) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Troy G. Garn (Idaho Falls, Idaho); Jack D. Law (Pocatello, Idaho); Mitchell R. Greenhalgh (Iona, Idaho); Troy J. Tranter (Mena, Arizona) |
| ABSTRACT | A composite media including at least one crystalline aluminosilicate material in polyacrylonitrile. A method of forming a composite media is also disclosed. The method comprises dissolving polyacrylonitrile in an organic solvent to form a matrix solution. At least one crystalline aluminosilicate material is combined with the matrix solution to form a composite media solution. The organic solvent present in the composite media solution is diluted. The composite media solution is solidified. In addition, a method of processing a fluid stream is disclosed. The method comprises providing a beads of a composite media comprising at least one crystalline aluminosilicate material dispersed in a polyacrylonitrile matrix. The beads of the composite media are contacted with a fluid stream comprising at least one constituent. The at least one constituent is substantially removed from the fluid stream. |
| FILED | Tuesday, November 08, 2011 |
| APPL NO | 13/291214 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 524/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686172 | Hupp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evansville, Indiana) |
| INVENTOR(S) | Joseph T. Hupp (Northfield, Illinois); Omar K. Farha (Morton Grove, Illinois) |
| ABSTRACT | A method for the treatment of solvent-containing MOF material to increase its internal surface area involves introducing a liquid into the MOF in which liquid the solvent is miscible, subjecting the MOF to supercritical conditions for a time to form supercritical fluid, and releasing the supercritical conditions to remove the supercritcal fluid from the MOF. Prior to introducing the liquid into the MOF, occluded reaction solvent, such as DEF or DMF, in the MOF can be exchanged for the miscible solvent. |
| FILED | Friday, April 19, 2013 |
| APPL NO | 13/866194 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 556/121 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686358 | Ginger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Ginger (Seattle, Washington); Rajiv Giridharagopal (Seattle, Washington); David Moore (Seattle, Washington); Glennis Rayermann (Seattle, Washington); Obadiah Reid (Denver, Colorado) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | David Ginger (Seattle, Washington); Rajiv Giridharagopal (Seattle, Washington); David Moore (Seattle, Washington); Glennis Rayermann (Seattle, Washington); Obadiah Reid (Denver, Colorado) |
| ABSTRACT | Methods and apparatus are provided herein for time-resolved analysis of the effect of a perturbation (e.g., a light or voltage pulse) on a sample. By operating in the time domain, the provided method enables sub-microsecond time-resolved measurement of transient, or time-varying, forces acting on a cantilever. |
| FILED | Wednesday, September 14, 2011 |
| APPL NO | 13/232859 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/306 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686362 | Bakhtiari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sasan Bakhtiari (Darien, Illinois); Nachappa Gopalsami (Naperville, Illinois); Thomas W. Elmer (Westmont, Illinois); Apostolos C. Raptis (Downers Grove, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Sasan Bakhtiari (Darien, Illinois); Nachappa Gopalsami (Naperville, Illinois); Thomas W. Elmer (Westmont, Illinois); Apostolos C. Raptis (Downers Grove, Illinois) |
| ABSTRACT | A millimeter wavelength (MMW) measurement system for remote detection of object characteristics and methods for detecting such characteristics. The MMW measurement system comprises a front-end and an optional signal conditioning component. The MMW front-end includes an oscillator, a transceiver portion, and an antenna for focusing a detection component comprising micrometer level wavelength electromagnetic radiation onto the object. A portion of the electromagnetic radiation reflected by the object is received by the MMW measurement system, which is indicative of a displacement of the object. The MMW system may be configured to detect micrometer level displacement of the object disposed tens of meters from the MMW measurement system. In various embodiments the object may be a natural object, including a human, and the displacement may be indicative of a heart rate and/or a respiratory function. |
| FILED | Thursday, April 29, 2010 |
| APPL NO | 12/770438 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686363 | Timlin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerilyn A. Timlin (Albuquerque, New Mexico); Jesse S. Aaron (Salt Lake City, Utah) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Jerilyn A. Timlin (Albuquerque, New Mexico); Jesse S. Aaron (Salt Lake City, Utah) |
| ABSTRACT | A hyperspectral stimulated emission depletion (“STED”) microscope system for high-resolution imaging of samples labeled with multiple fluorophores (e.g., two to ten fluorophores). The hyperspectral STED microscope includes a light source, optical systems configured for generating an excitation light beam and a depletion light beam, optical systems configured for focusing the excitation and depletion light beams on a sample, and systems for collecting and processing data generated by interaction of the excitation and depletion light beams with the sample. Hyperspectral STED data may be analyzed using multivariate curve resolution analysis techniques to deconvolute emission from the multiple fluorophores. The hyperspectral STED microscope described herein can be used for multi-color, subdiffraction imaging of samples (e.g., materials and biological materials) and for analyzing a tissue by Förster Resonance Energy Transfer (“FRET”). |
| FILED | Monday, September 10, 2012 |
| APPL NO | 13/609057 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/339.70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686429 | Bergmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Bergmann (Chapel Hill, North Carolina); Matthew Donofrio (Raleigh, North Carolina); Sten Heikman (Goleta, California); Kevin S. Schneider (Cary, North Carolina); Kevin W. Haberern (Cary, North Carolina); John A. Edmond (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Michael Bergmann (Chapel Hill, North Carolina); Matthew Donofrio (Raleigh, North Carolina); Sten Heikman (Goleta, California); Kevin S. Schneider (Cary, North Carolina); Kevin W. Haberern (Cary, North Carolina); John A. Edmond (Durham, North Carolina) |
| ABSTRACT | Embodiments of the present invention are generally related to LED chips having improved overall emission by reducing the light-absorbing effects of barrier layers adjacent mirror contacts. In one embodiment, a LED chip comprises one or more LEDs, with each LED having an active region, a first contact under the active region having a highly reflective mirror, and a barrier layer adjacent the mirror. The barrier layer is smaller than the mirror such that it does not extend beyond the periphery of the mirror. In another possible embodiment, an insulator is further provided, with the insulator adjacent the barrier layer and adjacent portions of the mirror not contacted by the active region or by the barrier layer. In yet another embodiment, a second contact is provided on the active region. In a further embodiment, the barrier layer is smaller than the mirror such that the periphery of the mirror is at least 40% free of the barrier layer, and the second contact is below the first contact and accessible from the bottom of the chip. |
| FILED | Friday, June 24, 2011 |
| APPL NO | 13/168689 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/76 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686460 | Raffetto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark Raffetto (Santa Barbara, California); Jayesh Bharathan (Cary, North Carolina); Kevin Haberern (Cary, North Carolina); Michael Bergmann (Chapel Hill, North Carolina); David Emerson (Chapel Hill, North Carolina); James Ibbetson (Santa Barbara, California); Ting Li (Ventura, California) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Mark Raffetto (Santa Barbara, California); Jayesh Bharathan (Cary, North Carolina); Kevin Haberern (Cary, North Carolina); Michael Bergmann (Chapel Hill, North Carolina); David Emerson (Chapel Hill, North Carolina); James Ibbetson (Santa Barbara, California); Ting Li (Ventura, California) |
| ABSTRACT | A flip-chip semiconductor based Light Emitting Device (LED) can include an n-type semiconductor substrate and an n-type GaN epi-layer on the substrate. A p-type GaN epi-layer can be on the n-type GaN epi-layer and a metal ohmic contact p-electrode can be on the p-type GaN epi-layer, where the metal ohmic contact p-electrode can have an average thickness less than about 25 Å. A reflector can be on the metal ohmic contact p-electrode and a metal stack can be on the reflector. An n-electrode can be on the substrate opposite the n-type GaN epi-layer and a bonding pad can be on the n-electrode. |
| FILED | Wednesday, October 12, 2011 |
| APPL NO | 13/271865 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686627 | Vardeny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zeev Valentine Vardeny (Salt Lake City, Utah); Chuanzhen Liu (Beijing, China PRC); Vladimir Kamaev (Saratov Region, Russian Federation) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Zeev Valentine Vardeny (Salt Lake City, Utah); Chuanzhen Liu (Beijing, China PRC); Vladimir Kamaev (Saratov Region, Russian Federation) |
| ABSTRACT | An organic light emitting diode (OLED) uses a π-conjugated polymer emissive layer (MEH-PPV) sandwiched between two semitransparent electrodes. The preferred embodiment utilizes an optically thin gold film anode, whereas the cathode was in the form of an optically thick aluminum (Al) film with patterned periodic subwavelength 2D hole array that showed anomalous transmission in the spectral range of the polymer photoluminescence band. At similar current densities we obtained a seven-fold electroluminescence efficiency enhancement with the patterned Al device compared with a control device based on unperforated Al electrode. |
| FILED | Friday, April 14, 2006 |
| APPL NO | 11/404646 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/504 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686804 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Batelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Stephen Fulton Smith (Loudon, Tennessee); James Anthony Moore (Powell, Tennessee) |
| ABSTRACT | An orthogonally referenced integrated ensemble for navigation and timing includes a dual-polyhedral oscillator array, including an outer sensing array of oscillators and an inner clock array of oscillators situated inside the outer sensing array. The outer sensing array includes a first pair of sensing oscillators situated along a first axis of the outer sensing array, a second pair of sensing oscillators situated along a second axis of the outer sensing array, and a third pair of sensing oscillators situated along a third axis of the outer sensing array. The inner clock array of oscillators includes a first pair of clock oscillators situated along a first axis of the inner clock array, a second pair of clock oscillators situated along a second axis of the inner clock array, and a third pair of clock oscillators situated along a third axis of the inner clock array. |
| FILED | Friday, January 18, 2013 |
| APPL NO | 13/745438 |
| ART UNIT | 2843 — Electrical Circuits and Systems |
| CURRENT CPC | Oscillators 331/162 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686910 | Ives et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | R. Lawrence Ives (San Mateo, California); Yosuke M. Mizuhara (Palo Alto, California) |
| ASSIGNEE(S) | Calabazas Creek Research, Inc. (San Mateo, California) |
| INVENTOR(S) | R. Lawrence Ives (San Mateo, California); Yosuke M. Mizuhara (Palo Alto, California) |
| ABSTRACT | A load for traveling microwave energy has an absorptive volume defined by cylindrical body enclosed by a first end cap and a second end cap. The first end cap has an aperture for the passage of an input waveguide with a rotating part that is coupled to a reflective mirror. The inner surfaces of the absorptive volume consist of a resistive material or are coated with a coating which absorbs a fraction of incident RF energy, and the remainder of the RF energy reflects. The angle of the reflector and end caps is selected such that reflected RF energy dissipates an increasing percentage of the remaining RF energy at each reflection, and the reflected RF energy which returns to the rotating mirror is directed to the back surface of the rotating reflector, and is not coupled to the input waveguide. Additionally, the reflector may have a surface which generates a more uniform power distribution function axially and laterally, to increase the power handling capability of the RF load. The input waveguide may be corrugated for HE11 mode input energy. |
| FILED | Monday, April 12, 2010 |
| APPL NO | 12/758614 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/772 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687261 | Gillaspie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dane T. Gillaspie (Fremont, California); Douglas G. Weir (Northfield, Minnesota) |
| ASSIGNEE(S) | SAGE Electrochromics, Inc. (Faribault, Minnesota); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Dane T. Gillaspie (Fremont, California); Douglas G. Weir (Northfield, Minnesota) |
| ABSTRACT | An electrochromic device comprising a counter electrode layer comprised of lithium metal oxide which provides a high transmission in the fully intercalated state and which is capable of long-term stability, is disclosed. Methods of making an electrochromic device comprising such a counter electrode are also disclosed. |
| FILED | Friday, July 20, 2012 |
| APPL NO | 13/554144 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687270 | Manes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth R. Manes (Brentwood, California); Mary L. Spaeth (Brentwood, California); Alvin C. Erlandson (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Kenneth R. Manes (Brentwood, California); Mary L. Spaeth (Brentwood, California); Alvin C. Erlandson (Livermore, California) |
| ABSTRACT | A main amplifier system includes a first reflector operable to receive input light through a first aperture and direct the input light along an optical path. The input light is characterized by a first polarization. The main amplifier system also includes a first polarizer operable to reflect light characterized by the first polarization state. The main amplifier system further includes a first and second set of amplifier modules. Each of the first and second set of amplifier modules includes an entrance window, a quarter wave plate, a plurality of amplifier slablets arrayed substantially parallel to each other, and an exit window. The main amplifier system additionally includes a set of mirrors operable to reflect light exiting the first set of amplifier modules to enter the second set of amplifier modules and a second polarizer operable to reflect light characterized by a second polarization state. |
| FILED | Friday, March 25, 2011 |
| APPL NO | 13/072581 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/346 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687364 | Chainer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy J. Chainer (Putnam Valley, New York); Patrick A. Coico (Fishkill, New York); David P. Graybill (Staatsburg, New York); Madhusudan K. Iyengar (Woodstock, New York); Vinod Kamath (Raleigh, North Carolina); Bejoy J. Kochuparambil (Apex, North Carolina); Roger R. Schmidt (Poughkeepsie, New York); Mark E. Steinke (Durham, North Carolina) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); Patrick A. Coico (Fishkill, New York); David P. Graybill (Staatsburg, New York); Madhusudan K. Iyengar (Woodstock, New York); Vinod Kamath (Raleigh, North Carolina); Bejoy J. Kochuparambil (Apex, North Carolina); Roger R. Schmidt (Poughkeepsie, New York); Mark E. Steinke (Durham, North Carolina) |
| ABSTRACT | A cooling apparatus for an electronics rack is provided which includes an air-to-liquid heat exchanger, one or more coolant-cooled structures and a tube. The heat exchanger, which is associated with the electronics rack and disposed to cool air passing through the rack, includes a plurality of distinct, coolant-carrying tube sections, each tube section having a coolant inlet and a coolant outlet, one of which is coupled in fluid communication with a coolant loop to facilitate flow of coolant through the tube section. The coolant-cooled structure(s) is in thermal contact with an electronic component(s) of the rack, and facilitates transfer of heat from the component(s) to the coolant. The tube connects in fluid communication one coolant-cooled structure and the other of the coolant inlet or outlet of the one tube section, and facilitates flow of coolant directly between that coolant-carrying tube section of the heat exchanger and the coolant-cooled structure. |
| FILED | Friday, October 28, 2011 |
| APPL NO | 13/283933 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/694 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687665 | Tauke-Pedretti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anna Tauke-Pedretti (Albuquerque, New Mexico); Erik J. Skogen (Albuquerque, New Mexico); Gregory A. Vawter (Corrales, New Mexico); Weng W. Chow (Cedar Crest, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Anna Tauke-Pedretti (Albuquerque, New Mexico); Erik J. Skogen (Albuquerque, New Mexico); Gregory A. Vawter (Corrales, New Mexico); Weng W. Chow (Cedar Crest, New Mexico) |
| ABSTRACT | Semiconductor light-emitting devices; methods of forming semi-conductor light emitting devices, and methods of operating semi-conductor light emitting devices are provided. A semiconductor light-emitting device includes a first laser section monolithically integrated with a second laser section on a common substrate. Each laser section has a phase section, a gain section and at least one distributed Bragg reflector (DBR) structure. The first laser section and the second laser section are optically coupled to permit optical feedback therebetween. Each phase section is configured to independently tune a respective one of the first laser section and second laser section relative to each other. |
| FILED | Thursday, September 15, 2011 |
| APPL NO | 13/233221 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/97 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687674 | Brocato |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert W. Brocato (Sandia Park, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Robert W. Brocato (Sandia Park, New Mexico) |
| ABSTRACT | A surface acoustic wave (SAW) correlator spread-spectrum (SS) receiver is disclosed which utilizes a first demodulation stage with a chip length n and a second demodulation stage with a chip length m to decode a transmitted SS signal having a code length l=n×m which can be very long (e.g. up to 2000 chips or more). The first demodulation stage utilizes a pair of SAW correlators which demodulate the SS signal to generate an appropriate code sequence at an intermediate frequency which can then be fed into the second demodulation stage which can be formed from another SAW correlator, or by a digital correlator. A compound SAW correlator comprising two input transducers and a single output transducer is also disclosed which can be used to form the SAW correlator SS receiver, or for use in processing long code length signals. |
| FILED | Thursday, October 06, 2005 |
| APPL NO | 11/245358 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/151 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688903 | Hemmert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Karl Scott Hemmert (Albuquerque, New Mexico); Keith D. Underwood (Powell, Tennessee) |
| ABSTRACT | An associative list processing unit and method comprising employing a plurality of prioritized cell blocks and permitting inserts to occur in a single clock cycle if all of the cell blocks are not full. |
| FILED | Thursday, December 13, 2012 |
| APPL NO | 13/714098 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Memory 711/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08685185 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chunlei Guo (Rochester, New York); Anatoliy Y. Vorobyev (St. Catharines, Canada) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Chunlei Guo (Rochester, New York); Anatoliy Y. Vorobyev (St. Catharines, Canada) |
| ABSTRACT | Embodiments of the present invention are generally directed to materials processing methods using femtosecond duration laser pulses, and to the altered materials obtained by such methods. The resulting nanostructured (with or without macro- and micro-structuring) materials have a variety of applications, including, for example, aesthetic applications for jewelry or ornamentation; biomedical applications related to biocompatibility; catalysis applications; and modification of, for example, the optical and hydrophilic properties of materials including selective coloring. |
| FILED | Wednesday, October 05, 2011 |
| APPL NO | 13/253173 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Metal treatment 148/565 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685706 | Paulsen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven R. Paulsen (Kimberly, Idaho) |
| ASSIGNEE(S) | Living Earth, LLC (Kimberly, Idaho) |
| INVENTOR(S) | Steven R. Paulsen (Kimberly, Idaho) |
| ABSTRACT | The present invention relates to a process for restoring disturbed arid land soil crust. According to the process, site-sourced biological soil crusts (BSC) serve as sources for liquid suspension inoculants onto degraded arid lands. The BSC are gathered from near the disturbed site, and organisms from them are cultured, replicated and multiplied many times, preferably off-site. Then, this inoculant resulting from the indigenous population is distributed live and active in a liquid suspension over the entire area of the disturbed site. |
| FILED | Tuesday, November 09, 2010 |
| APPL NO | 12/942963 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/257.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685729 | Clark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Douglas S. Clark (Orinda, California); Timothy Whitehead (Berkeley, California); Frank T. Robb (Gaithersburg, Maryland); Pongpan Laksanalamai (Baltimore, Maryland); Anchalee Jiemjit (Baltimore, Maryland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Douglas S. Clark (Orinda, California); Timothy Whitehead (Berkeley, California); Frank T. Robb (Gaithersburg, Maryland); Pongpan Laksanalamai (Baltimore, Maryland); Anchalee Jiemjit (Baltimore, Maryland) |
| ABSTRACT | The invention provides methods and compositions for increasing tolerance of microorganisms to toxic agents, such as solvents; and for increasing production of solvents from solvent-generating microorganisms. The methods comprise engineering a microorganism of interest to express a heterologous heat-shock protein/chaperone, e.g., Group II chaperonin or a prefoldin such as γ-prefoldin, where the heterologous protein is from an extremophile, such as an archaean. |
| FILED | Tuesday, February 26, 2008 |
| APPL NO | 12/528620 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08685743 — Real-time, single-step bioassay using nanoplasmonic resonator with ultra-high sensitivity
| US 08685743 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ABSTRACT | A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/772118 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685767 | Tansu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nelson Tansu (Bethlehem, Pennsylvania); Hongping Zhao (Bethlehem, Pennsylvania); Jing Zhang (Bethlehem, Pennsylvania); Guangyu Liu (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Nelson Tansu (Bethlehem, Pennsylvania); Hongping Zhao (Bethlehem, Pennsylvania); Jing Zhang (Bethlehem, Pennsylvania); Guangyu Liu (Bethlehem, Pennsylvania) |
| ABSTRACT | A double-metallic deposition process is used whereby adjacent layers of different metals are deposited on a substrate. The surface plasmon frequency of a base layer of a first metal is tuned by the surface plasmon frequency of a second layer of a second metal formed thereon. The amount of tuning is dependent upon the thickness of the metallic layers, and thus tuning can be achieved by varying the thicknesses of one or both of the metallic layers. In a preferred embodiment directed to enhanced LED technology in the green spectrum regime, a double-metallic Au/Ag layer comprising a base layer of gold (Au) followed by a second layer of silver (Ag) formed thereon is deposited on top of InGaN/GaN quantum wells (QWs) on a sapphire/GaN substrate. |
| FILED | Wednesday, December 08, 2010 |
| APPL NO | 12/963117 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/29 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685841 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jiatao Zhang (Beijing, China PRC); Yun Tang (Cambridge, Massachusetts); Min Ouyang (Kensington, Maryland) |
| ASSIGNEE(S) | University of Maryland College Park (College Park, Maryland) |
| INVENTOR(S) | Jiatao Zhang (Beijing, China PRC); Yun Tang (Cambridge, Massachusetts); Min Ouyang (Kensington, Maryland) |
| ABSTRACT | The present invention is directed to a novel synthetic method for producing nanoscale heterostructures, and particularly nanoscale heterostructure particles, rods and sheets, that comprise a metal core and a monocrystalline semiconductor shell with substantial lattice mismatches between them. More specifically, the invention concerns the use of controlled soft acid-base coordination reactions between molecular complexes and colloidal nanostructures to drive the nanoscale monocrystalline growth of the semiconductor shell with a lattice structure incommensurate with that of the core. The invention also relates to more complex hybrid core-shell structures that exhibit azimuthal and radial nano-tailoring of structures. The invention is additionally directed to the use of such compositions in semiconductor devices. |
| FILED | Friday, March 23, 2012 |
| APPL NO | 13/428516 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/478 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686358 | Ginger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Ginger (Seattle, Washington); Rajiv Giridharagopal (Seattle, Washington); David Moore (Seattle, Washington); Glennis Rayermann (Seattle, Washington); Obadiah Reid (Denver, Colorado) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | David Ginger (Seattle, Washington); Rajiv Giridharagopal (Seattle, Washington); David Moore (Seattle, Washington); Glennis Rayermann (Seattle, Washington); Obadiah Reid (Denver, Colorado) |
| ABSTRACT | Methods and apparatus are provided herein for time-resolved analysis of the effect of a perturbation (e.g., a light or voltage pulse) on a sample. By operating in the time domain, the provided method enables sub-microsecond time-resolved measurement of transient, or time-varying, forces acting on a cantilever. |
| FILED | Wednesday, September 14, 2011 |
| APPL NO | 13/232859 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/306 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686359 | Zewail |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ahmed H. Zewail (Pasadena, California) |
| ABSTRACT | The present invention relates to methods and systems for 4D ultrafast electron microscopy (UEM)—in situ imaging with ultrafast time resolution in TEM. Single electron imaging is used as a component of the 4D UEM technique to provide high spatial and temporal resolution unavailable using conventional techniques. Other embodiments of the present invention relate to methods and systems for convergent beam UEM, focusing the electron beams onto the specimen to measure structural characteristics in three dimensions as a function of time. Additionally, embodiments provide not only 4D imaging of specimens, but characterization of electron energy, performing time resolved electron energy loss spectroscopy (EELS). |
| FILED | Tuesday, April 16, 2013 |
| APPL NO | 13/864113 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686627 | Vardeny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zeev Valentine Vardeny (Salt Lake City, Utah); Chuanzhen Liu (Beijing, China PRC); Vladimir Kamaev (Saratov Region, Russian Federation) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Zeev Valentine Vardeny (Salt Lake City, Utah); Chuanzhen Liu (Beijing, China PRC); Vladimir Kamaev (Saratov Region, Russian Federation) |
| ABSTRACT | An organic light emitting diode (OLED) uses a π-conjugated polymer emissive layer (MEH-PPV) sandwiched between two semitransparent electrodes. The preferred embodiment utilizes an optically thin gold film anode, whereas the cathode was in the form of an optically thick aluminum (Al) film with patterned periodic subwavelength 2D hole array that showed anomalous transmission in the spectral range of the polymer photoluminescence band. At similar current densities we obtained a seven-fold electroluminescence efficiency enhancement with the patterned Al device compared with a control device based on unperforated Al electrode. |
| FILED | Friday, April 14, 2006 |
| APPL NO | 11/404646 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric lamp and discharge devices 313/504 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686721 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian J. Anderson (Mt. Airy, Maryland); Lars P. Dyrud (Crownsville, Maryland); Jonathan T. Fentzke (Crownsville, Maryland); Robin J. Barnes (Elkridge, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Brian J. Anderson (Mt. Airy, Maryland); Lars P. Dyrud (Crownsville, Maryland); Jonathan T. Fentzke (Crownsville, Maryland); Robin J. Barnes (Elkridge, Maryland) |
| ABSTRACT | A system, method and computer-readable medium for mapping magnetic activity for a current linking a planet's space environment to an ionosphere of the planet are disclosed. Magnetic field measurements of the current are obtained from a plurality of satellites orbiting the planet. A residual magnetic field is determined from the obtained magnetic field measurements. The determined residual magnetic field is arranged to create a time series for a selected location of a planet-centered coordinate system. The magnetic activity is mapped using the created time series for the selected location. |
| FILED | Thursday, April 19, 2012 |
| APPL NO | 13/450851 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/244 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687689 | Baraniuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard Baraniuk (Houston, Texas); Dror Z. Baron (Houston, Texas); Marco F. Duarte (Houston, Texas); Mohamed Elnozahi (Houston, Texas); Michael B. Wakin (Ann Arbor, Michigan); Mark A. Davenport (Houston, Texas); Jason N. Laska (Houston, Texas); Joel A. Tropp (Ann Arbor, Michigan); Yehia Massoud (Houston, Texas); Sami Kirolos (Houston, Texas); Tamer Ragheb (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Richard Baraniuk (Houston, Texas); Dror Z. Baron (Houston, Texas); Marco F. Duarte (Houston, Texas); Mohamed Elnozahi (Houston, Texas); Michael B. Wakin (Ann Arbor, Michigan); Mark A. Davenport (Houston, Texas); Jason N. Laska (Houston, Texas); Joel A. Tropp (Ann Arbor, Michigan); Yehia Massoud (Houston, Texas); Sami Kirolos (Houston, Texas); Tamer Ragheb (Houston, Texas) |
| ABSTRACT | A typical data acquisition system takes periodic samples of a signal, image, or other data, often at the so-called Nyquist/Shannon sampling rate of two times the data bandwidth in order to ensure that no information is lost. In applications involving wideband signals, the Nyquist/Shannon sampling rate is very high, even though the signals may have a simple underlying structure. Recent developments in mathematics and signal processing have uncovered a solution to this Nyquist/Shannon sampling rate bottlenck for signals that are sparse or compressible in some representation. We demonstrate and reduce to practice methods to extract information directly from an analog or digital signal based on altering our notion of sampling to replace uniform time samples with more general linear functionals. One embodiment of our invention is a low-rate analog-to-information converter that can replace the high-rate analog-to-digital converter in certain applications involving wideband signals. Another embodiment is an encoding scheme for wideband discrete-time signals that condenses their information content. |
| FILED | Wednesday, October 25, 2006 |
| APPL NO | 12/091340 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Pulse or digital communications 375/240.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688375 | Funk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Benjamin E. Funk (Silver Spring, Maryland); Amrit Bandyopadhyay (Greenbelt, Maryland); Eric A. Kohn (Washington, District of Columbia); Neil Goldsman (Takoma Park, Maryland); Carole A. Teolis (Glendale, Maryland); Gilmer L. Blankenship (Washington, District of Columbia) |
| ASSIGNEE(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
| INVENTOR(S) | Benjamin E. Funk (Silver Spring, Maryland); Amrit Bandyopadhyay (Greenbelt, Maryland); Eric A. Kohn (Washington, District of Columbia); Neil Goldsman (Takoma Park, Maryland); Carole A. Teolis (Glendale, Maryland); Gilmer L. Blankenship (Washington, District of Columbia) |
| ABSTRACT | The present invention is directed to methods and systems for locating and monitoring the status of people and moveable assets, such as first responders, including firefighters and other public service personnel, and their equipment both indoors and out. The invention can provide for locating and monitoring the status of people and assets in environments where GPS systems do not operate, or where operation is impaired or otherwise limited. The system and method uses inertial navigation to determine the location, motion and orientation of the personnel or assets and communicates with an external monitoring station to receive requests for location, motion orientation and status information and to transmit the location, motion orientation and status information to the monitoring station. The system and method can include storing the location, motion and orientation data as well as status data, in the event that the communication system is unable to communicate with and transmit information to the monitoring station, the system will wait until communication is restored and transmit the status information to the monitoring station to update the location, motion orientation and status information for the person or asset. |
| FILED | Thursday, May 31, 2007 |
| APPL NO | 11/756412 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/495 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688434 | Birnbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence A. Birnbaum (Evanston, Illinois); Kristian J. Hammond (Chicago, Illinois); Nicholas D. Allen (Chicago, Illinois); John R. Templon (Chicago, Illinois) |
| ASSIGNEE(S) | Narrative Science Inc. (Chicago, Illinois) |
| INVENTOR(S) | Lawrence A. Birnbaum (Evanston, Illinois); Kristian J. Hammond (Chicago, Illinois); Nicholas D. Allen (Chicago, Illinois); John R. Templon (Chicago, Illinois) |
| ABSTRACT | A system and method for automatically generating a narrative story receives data and information pertaining to a domain event. The received data and information and/or one or more derived features are then used to identify a plurality of angles for the narrative story. The plurality of angles is then filtered, for example through use of parameters that specify a focus for the narrative story, length of the narrative story, etc. Points associated with the filtered plurality of angles are then assembled and the narrative story is rendered using the filtered plurality of angles and the assembled points. |
| FILED | Thursday, May 13, 2010 |
| APPL NO | 12/779636 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688617 | Morgan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew A. Morgan (Earlysville, Virginia); James R. Fisher (Crozet, Virginia) |
| ASSIGNEE(S) | Associated Universities, Inc. (Washington, District of Columbia) |
| INVENTOR(S) | Matthew A. Morgan (Earlysville, Virginia); James R. Fisher (Crozet, Virginia) |
| ABSTRACT | Methods, systems, and devices using an algorithm that consists of scoring the bits in the data stream with a periodicity of N, where N is the word-length in bits, and then selecting as the most significant bit the one which receives the highest score after some large number of samples are disclosed. The condition under which bit bk receives a point depends on the binary format. |
| FILED | Wednesday, July 20, 2011 |
| APPL NO | 13/186739 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/52 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688791 | Sheth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amit Sheth (Dayton, Ohio); Karthik Gomadam (San Jose, California); Meenakshi Nagarajan (San Jose, California) |
| ASSIGNEE(S) | Wright State University (Dayton, Ohio) |
| INVENTOR(S) | Amit Sheth (Dayton, Ohio); Karthik Gomadam (San Jose, California); Meenakshi Nagarajan (San Jose, California) |
| ABSTRACT | The present invention generally relates to methods and systems for analysis of real-time user-generated text messages. The methods and systems allow analysis to be performed using term associations and geographical and temporal constraints. |
| FILED | Wednesday, February 16, 2011 |
| APPL NO | 13/028397 |
| ART UNIT | 2479 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08689282 | Oprea et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alina M. Oprea (Arlington, Massachusetts); Yinqian Zhang (Chapel Hill, North Carolina); Vijay Ganti (Lexington, Massachusetts); John P. Field (Chatham, New Jersey); Ari Juels (Brookline, Massachusetts); Michael Kendrick Reiter (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | EMC Corporation (Hopkinton, Massachusetts); University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Alina M. Oprea (Arlington, Massachusetts); Yinqian Zhang (Chapel Hill, North Carolina); Vijay Ganti (Lexington, Massachusetts); John P. Field (Chatham, New Jersey); Ari Juels (Brookline, Massachusetts); Michael Kendrick Reiter (Chapel Hill, North Carolina) |
| ABSTRACT | Cloud infrastructure of a cloud service provider comprises a processing platform implementing a security policy enforcement framework. The security policy enforcement framework comprises a policy analyzer that is configured to identify at least one security policy associated with at least one tenant of the cloud service provider, to analyze the security policy against configuration information characterizing the cloud infrastructure of the cloud service provider, and to control execution of one or more applications of said at least one tenant within the cloud infrastructure in accordance with the security policy, based at least in part on one or more results of the analysis of the security policy. The security policy enforcement framework may be implemented in a platform-as-a-service (PaaS) layer of the cloud infrastructure, and may comprise a runtime controller, an operating system controller, a hypervisor controller and a PaaS controller. |
| FILED | Friday, December 23, 2011 |
| APPL NO | 13/336692 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Information security 726/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08683807 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Travis L. Turner (Yorktown, Virginia); Roberto J. Cano (Yorktown, Virginia); Richard J. Silox (Poquoson, Virginia); Ralph D. Buehrle (Williamsburg, Virginia); Christopher M. Cagle (Yorktown, Virginia); Randolph H. Cabell (Hampton, Virginia); George C. Hilton (Hampton, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Travis L. Turner (Yorktown, Virginia); Roberto J. Cano (Yorktown, Virginia); Richard J. Silox (Poquoson, Virginia); Ralph D. Buehrle (Williamsburg, Virginia); Christopher M. Cagle (Yorktown, Virginia); Randolph H. Cabell (Hampton, Virginia); George C. Hilton (Hampton, Virginia) |
| ABSTRACT | A jet engine exhaust nozzle flow effector is a chevron formed with a radius of curvature with surfaces of the flow effector being defined and opposing one another. At least one shape memory alloy (SMA) member is embedded in the chevron closer to one of the chevron's opposing surfaces and substantially spanning from at least a portion of the chevron's root to the chevron's tip. |
| FILED | Thursday, April 28, 2011 |
| APPL NO | 13/096305 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/771 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685237 | Littman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Howard Littman (Niskayuna, New York); Joel L. Plawsky (Albany, New York); John D. Paccione (Voorheesville, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Howard Littman (Niskayuna, New York); Joel L. Plawsky (Albany, New York); John D. Paccione (Voorheesville, New York) |
| ABSTRACT | An improved draft tube spout fluid bed (DTSFB) mixing, handling, conveying, and treating apparatus and systems, and methods for operating are provided. The apparatus and systems can accept particulate material and pneumatically or hydraulically conveying the material to mix and/or treat the material. In addition to conveying apparatus, a collection and separation apparatus adapted to receive the conveyed particulate material is also provided. The collection apparatus may include an impaction plate against which the conveyed material is directed to improve mixing and/or treatment. The improved apparatus are characterized by means of controlling the operation of the pneumatic or hydraulic transfer to enhance the mixing and/or reacting by controlling the flow of fluids, for example, air, into and out of the apparatus. The disclosed apparatus may be used to mix particulate material, for example, mortar; react fluids with particulate material; coat particulate material, or simply convey particulate material. |
| FILED | Friday, November 06, 2009 |
| APPL NO | 12/614165 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/153 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685257 | Beringer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Durwood Mace Beringer (Suffield, Connecticut); John W. Steele (New Hartford, Connecticut); Timothy A. Nalette (West Stafford, Connecticut) |
| ASSIGNEE(S) | Hamilton Sundstrand Space Systems International, Inc. (Windsor Locks, Connecticut) |
| INVENTOR(S) | Durwood Mace Beringer (Suffield, Connecticut); John W. Steele (New Hartford, Connecticut); Timothy A. Nalette (West Stafford, Connecticut) |
| ABSTRACT | A method for controlling microbial growth in potable water stored in a vessel having a metallic surface includes heating the metallic surface to a temperature between about 480° C. (900° F.) and about 870° C. (1600° F.), exposing the metallic surface to oxygen during heating to oxidize potential reduction sites on the metallic surface and charging potable water containing silver ions to the vessel. A vessel having a metallic surface is prepared for long-term storage of potable water containing silver ions by heating the metallic surface to a temperature between about 480° C. (900° F.) and about 870° C. (1600° F.) and exposing the metallic surface to oxygen during heating to oxidize electropositive metals on the metallic surface or by treating the metallic surface with an aqueous solution containing on oxidizing agent to oxidize potential reduction sites on the metallic surface. |
| FILED | Thursday, December 10, 2009 |
| APPL NO | 12/635102 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/764 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685268 | Yee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Karl Y. Yee (Pasadena, California); Andrew P. Homyk (South Pasadena, California) |
| ABSTRACT | Disclosed herein is a textured substrate comprising a base comprising silicon, the base having a plurality of needle like structures depending away from the base, wherein at least one of the needle like structures has a depth of greater than or equal to about 50 micrometers determined perpendicular to the base, and wherein at least one of the needle like structures has a width of less than or equal to about 50 micrometers determined parallel to the base. An anode and a lithium ion battery comprising the textured substrate, and a method of producing the textured substrate are also disclosed. |
| FILED | Thursday, May 16, 2013 |
| APPL NO | 13/895499 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Etching a substrate: Processes 216/79 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685576 | Burke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth Alan Burke (Chardon, Ohio) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Alan Burke (Chardon, Ohio) |
| ABSTRACT | The present invention relates to an electrically conductive membrane that can be configured to be used in fuel cell systems to act as a hydrophilic water separator internal to the fuel cell, or as a water separator used with water vapor fed electrolysis cells, or as a water separator used with water vapor fed electrolysis cells, or as a capillary structure in a thin head pipe evaporator, or as a hydrophobic gas diffusion layer covering the fuel cell electrode surface in a fuel cell. |
| FILED | Tuesday, September 25, 2007 |
| APPL NO | 11/860661 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/414 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685728 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yufang Shi (Belle Mead, New Jersey); Guangwen Ren (Piscataway, New Jersey); Liying Zhang (Belle Mead, New Jersey) |
| ASSIGNEE(S) | Rutgers The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Yufang Shi (Belle Mead, New Jersey); Guangwen Ren (Piscataway, New Jersey); Liying Zhang (Belle Mead, New Jersey) |
| ABSTRACT | The present invention relates to a composition and methods of treatment for inflammation comprising of adult stem cells and inflammatory cytokines. The invention further relates to the treatment of inflammation associated with autoimmune disorders, allergies, sepsis, cancer as well as to preventing, reducing or treating transplant rejection and/or graft-versus-host disease (GvHD). |
| FILED | Friday, January 30, 2009 |
| APPL NO | 12/362847 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/372 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08685743 — Real-time, single-step bioassay using nanoplasmonic resonator with ultra-high sensitivity
| US 08685743 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiang Zhang (Alamo, California); Jonathan A. Ellman (Guilford, Connecticut); Fanqing Frank Chen (Moraga, California); Kai-Hang Su (Seoul, South Korea); Qi-Huo Wei (Kent, Ohio); Cheng Sun (Evanston, Illinois) |
| ABSTRACT | A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/772118 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685755 | Ferrari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugar Land, Texas); Ennio Tasciotti (Houston, Texas); Ali Bouamrani (Grenoble, France); Ye Hu (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Mauro Ferrari (Houston, Texas); Xuewu Liu (Sugar Land, Texas); Ennio Tasciotti (Houston, Texas); Ali Bouamrani (Grenoble, France); Ye Hu (Austin, Texas) |
| ABSTRACT | A new fractionation device shows desirable features for exploratory screening and biomarker discovery. The constituent MSCs may be tailored for desired pore sizes and surface properties and for the sequestration and enrichment of extremely low abundant protein and peptides in desired ranges of the mass/charge spectrum. The MSCs are effective in yielding reproducible extracts from complex biological samples as small as 10 μl in a time as short as 30 minutes. They are inexpensive to manufacture, and allow for scaled up production to attain the simultaneous processing of a large number of samples. The MSCs are multiplexed, label-free diagnostic tools with the potential of biological recognition moiety modification for enhanced specificity. The MSCs may store, protect and stabilize biological fluids, enabling the simplified and cost-effective collection and transportation of clinical samples. The MSC-based device may serve as a diagnostic tool to complement histopathology, imaging, and other conventional clinical techniques. The MSCs mediated identification of disease-specific protein signatures may help in the selection of personalized therapeutic combinations, in the real-time assessment of therapeutic efficacy and toxicity, and in the rational modulation of therapy based on the changes in the protein networks associated with the prognosis and the drug resistance of the disease. |
| FILED | Tuesday, July 20, 2010 |
| APPL NO | 12/839606 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/527 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687742 | Racette |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul E. Racette (Edgewater, Maryland) |
| ASSIGNEE(S) | The United Sates of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Paul E. Racette (Edgewater, Maryland) |
| ABSTRACT | An ensemble detector uses calibrated noise references to produce ensemble sets of data from which properties of non-stationary processes may be extracted. The ensemble detector comprising: a receiver; a switching device coupled to the receiver, the switching device configured to selectively connect each of a plurality of reference noise signals to the receiver; and a gain modulation circuit coupled to the receiver and configured to vary a gain of the receiver based on a forcing signal; whereby the switching device selectively connects each of the plurality of reference noise signals to the receiver to produce an output signal derived from the plurality of reference noise signals and the forcing signal. |
| FILED | Tuesday, June 07, 2011 |
| APPL NO | 13/154599 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/340 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688065 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence E. Young (La Canada, California); Dmitry Turbiner (Pasadena, California); Stephan X. Esterhuizen (Los Angeles, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lawrence E. Young (La Canada, California); Dmitry Turbiner (Pasadena, California); Stephan X. Esterhuizen (Los Angeles, California) |
| ABSTRACT | An electromagnetic signal receiver and methods for determining the noise level and signal power in a signal of interest while the receiver is operating. In some embodiments, the signal of interest is a GPS signal. The receiver includes a noise source that provides a noise signal of known power during intervals while the signal of interest is observed. By measuring a signal-to-noise ratio for the signal of interest and the noise power in the signal of interest, the noise level and signal power of the signal of interest can be computed. Various methods of making the measurements and computing the power of the signal of interest are described. Applications of the system and method are described. |
| FILED | Friday, August 31, 2012 |
| APPL NO | 13/601581 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 17/004 (20130101) Original (OR) Class Wireless Communication Networks H04W 24/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08689083 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thuy V. Nguyen (Dallas, Texas); Aria Nosratinia (Plano, Texas); Dariush Divsalar (Pacific Palisades, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Thuy V. Nguyen (Dallas, Texas); Aria Nosratinia (Plano, Texas); Dariush Divsalar (Pacific Palisades, California) |
| ABSTRACT | Digital communication coding methods resulting in rate-compatible low density parity-check (LDPC) codes built from protographs. Described digital coding methods start with a desired code rate and a selection of the numbers of variable nodes and check nodes to be used in the protograph. Constraints are set to satisfy a linear minimum distance growth property for the protograph. All possible edges in the graph are searched for the minimum iterative decoding threshold and the protograph with the lowest iterative decoding threshold is selected. Protographs designed in this manner are used in decode and forward relay channels. |
| FILED | Friday, June 10, 2011 |
| APPL NO | 13/158263 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/774 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08685201 | O'Rourke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shawn O'Rourke (Tempe, Arizona); Douglas Loy (Chandler, Arizona); Hanqing Jiang (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Shawn O'Rourke (Tempe, Arizona); Douglas Loy (Chandler, Arizona); Hanqing Jiang (Chandler, Arizona) |
| ABSTRACT | Methods are described for addressing the bowing and/or warping of flexible substrates, attached to a rigid carrier, which occurs as a result of the thermal challenges of semiconductor processing. In particular, viscoelastic adhesives are provided which can bond a flexible substrate to a rigid carrier and mediate the thermal mismatch which often is present due to the distinctly different materials properties of most flexible substrates, such as plastic films, with respect to rigid carriers, such as silicon wafers. Assemblies are also provided which are produced according to the methods described herein. |
| FILED | Monday, April 06, 2009 |
| APPL NO | 12/921896 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685237 | Littman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Howard Littman (Niskayuna, New York); Joel L. Plawsky (Albany, New York); John D. Paccione (Voorheesville, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Howard Littman (Niskayuna, New York); Joel L. Plawsky (Albany, New York); John D. Paccione (Voorheesville, New York) |
| ABSTRACT | An improved draft tube spout fluid bed (DTSFB) mixing, handling, conveying, and treating apparatus and systems, and methods for operating are provided. The apparatus and systems can accept particulate material and pneumatically or hydraulically conveying the material to mix and/or treat the material. In addition to conveying apparatus, a collection and separation apparatus adapted to receive the conveyed particulate material is also provided. The collection apparatus may include an impaction plate against which the conveyed material is directed to improve mixing and/or treatment. The improved apparatus are characterized by means of controlling the operation of the pneumatic or hydraulic transfer to enhance the mixing and/or reacting by controlling the flow of fluids, for example, air, into and out of the apparatus. The disclosed apparatus may be used to mix particulate material, for example, mortar; react fluids with particulate material; coat particulate material, or simply convey particulate material. |
| FILED | Friday, November 06, 2009 |
| APPL NO | 12/614165 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/153 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685747 | Zenhausern et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederic Zenhausern (Fountain Hills, Arizona); Ralf Lenigk (Chandler, Arizona); James Kinder (Bellevue, Washington); Jianing Yang (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, A body corporate of the State of Arizona Acting for and on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Frederic Zenhausern (Fountain Hills, Arizona); Ralf Lenigk (Chandler, Arizona); James Kinder (Bellevue, Washington); Jianing Yang (Tempe, Arizona) |
| ABSTRACT | Methods, apparatuses, and systems for collecting samples using hybrid porous materials that include an organic material and an inorganic material. A method for sample collection includes contacting a hybrid porous material and a biological sample to the porous material. The hybrid porous material includes an inorganic material and an organic material. The method includes placing the porous material with the attached sample in a liquid medium, wherein the sample is separated from the porous material in the liquid medium to form a separated sample, and collecting the separated sample in the medium. |
| FILED | Friday, August 14, 2009 |
| APPL NO | 13/121031 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/174 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685894 | Chaput et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Chaput (Phoenix, Arizona); Stuart Lindsay (Phoenix, Arizona); Hao Yan (Chandler, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, A body Corporate of the State of Arizona Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | John Chaput (Phoenix, Arizona); Stuart Lindsay (Phoenix, Arizona); Hao Yan (Chandler, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | The present invention provides finite, addressable, and self-assembling nucleic acid tiling arrays, and methods for their use. |
| FILED | Wednesday, May 23, 2007 |
| APPL NO | 12/301884 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08687759 | Reyes, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jose N. Reyes, Jr. (Corvallis, Oregon); John T. Groome (Corvallis, Oregon) |
| ASSIGNEE(S) | The State of Oregon Acting by and Through the State Board of Higher Education on Behalf of Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Jose N. Reyes, Jr. (Corvallis, Oregon); John T. Groome (Corvallis, Oregon) |
| ABSTRACT | A power module assembly includes a reactor core immersed in a coolant and a reactor vessel housing the coolant and the reactor core. An internal dry containment vessel submerged in liquid substantially surrounds the reactor vessel in a gaseous environment. During an over-pressurization event the reactor vessel is configured to release the coolant into the containment vessel and remove a decay heat of the reactor core through condensation of the coolant on an inner surface of the containment vessel. |
| FILED | Thursday, November 15, 2007 |
| APPL NO | 11/941024 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/347 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08685404 | Loftis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jennifer Loftis (Portland, Oregon); Marilyn Huckans (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jennifer Loftis (Portland, Oregon); Marilyn Huckans (Portland, Oregon); Arthur A. Vandenbark (Portland, Oregon) |
| ABSTRACT | Methods are provided for the treatment of subjects with cognitive or neuropsychiatric impairment induced by substance addiction and for increasing cognitive function in a subject with substance addiction. In some embodiments, the methods include administering to the subject a therapeutically effective amount of a major histocompatibility complex (MHC) molecule including covalently linked first, second, and third domains; wherein the first domain is an MHC class II β1 domain and the second domain is an MHC class II α1 domain; or wherein the first domain is an MHC class I α1 domain and the second domain is an MHC class I α2 domain; and wherein the third domain is covalently linked to the first domain and comprises an antigen of the central or peripheral nervous system. |
| FILED | Monday, January 30, 2012 |
| APPL NO | 13/361720 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685411 | Dormitzer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Philip R. Dormitzer (Cambridge, Massachusetts); Stephen C. Harrison (Cambridge, Massachusetts); Harry B. Greenberg (Palo Alto, California); Joshua Yoder (Newtown, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States of America as represented by the National Institutes of Health (NIH) (Washington, District of Columbia); The United States of America as represented by the Dept. of Health and Human Services (DHHS) (Washington, District of Columbia) |
| INVENTOR(S) | Philip R. Dormitzer (Cambridge, Massachusetts); Stephen C. Harrison (Cambridge, Massachusetts); Harry B. Greenberg (Palo Alto, California); Joshua Yoder (Newtown, Massachusetts) |
| ABSTRACT | The present invention relates to novel recombinant polypeptide antigens that may comprise subunit vaccines against rotavirus infection. Further, the present invention relates to methods for use of said antigens in the diagnosis, treatment and prevention of rotavirus infection. |
| FILED | Wednesday, January 03, 2007 |
| APPL NO | 11/649191 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/215.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685938 | Goronzy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jorg J Goronzy (Palo Alto, California); Cornelia Weyand (Palo Alto, California); Mingcan Yu (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jorg J Goronzy (Palo Alto, California); Cornelia Weyand (Palo Alto, California); Mingcan Yu (Palo Alto, California) |
| ABSTRACT | The present invention provides methods for restoring or enhancing T cell mediated immune response in individuals of middle and advanced age. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/082790 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686045 | Longo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Frank M. Longo (Menlo Park, California); Stephen M. Massa (Burlingame, California) |
| ABSTRACT | Methods and compounds for treating neurological and other disorders are provided. Included is the administering to a subject in need thereof an effective amount of a compound having binding and/or modulation specificity for a TrkB receptor molecule. |
| FILED | Thursday, June 08, 2006 |
| APPL NO | 11/449381 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/616 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08686764 | Bulzacchelli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | John F. Bulzacchelli (Yonkers, New York); Ankur Agrawal (White Plains, New York) |
| ABSTRACT | Circuits and methods are provided for generating clock signals and correcting duty cycle distortion in clock signals. A circuit for generating a clock signal includes a multiplexer circuit and an edge-triggered flip-flop circuit. The multiplexer circuit selectively outputs one of a plurality of input clock signals. The edge-triggered flip-flop detects a transitioning edge of the input clock signal that is selectively output from the multiplexer circuit, and in response to the detection, samples a logic level of a received data signal, and generates a transition of an output clock signal at an output port of the edge-triggered flip-flop. The multiplexer circuit selectively outputs one of the plurality of input clock signals to a clock signal port of the edge-triggered flip-flop, based on a logic level of the output clock signal at the output port of the edge-triggered flip-flop, which is input to a select control port of the multiplexer circuit. |
| FILED | Monday, July 22, 2013 |
| APPL NO | 13/947224 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688850 | Branson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Zhen Liu (Tarrytown, New York); Fan Ye (Ossining, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Zhen Liu (Tarrytown, New York); Fan Ye (Ossining, New York) |
| ABSTRACT | A cooperative data stream processing system is provided that utilizes a plurality of independent, autonomous and potentially heterogeneous sites in a cooperative arrangement to process user-defined inquiries over dynamic, continuous streams of data. The system derives jobs from the inquiries and these jobs are executed on the various distributed sites by executing applications containing processing elements on these sites. Therefore, components of a given job can be executed simultaneously and in parallel on a plurality of sites within in the system. The sites associated with a given job execution have the need to share data, both primal and derived. A tunnel mechanism is provided that establishes tunnels between pairs of sites within the system. Each tunnel includes either a sink processing element on an originating site and a source processing element on a destination site or a gateway processing element on each site and a network connection between the sink and source processing elements. The sink and source processing elements are in communication with application processing elements on their respective sites and facilitate the exchange of data between these application processing elements. Tunnels can be establish on demand or in accordance with a prescribed plan and can be job specific of generic to any job executing on a given pair of sites. |
| FILED | Friday, May 11, 2007 |
| APPL NO | 11/747694 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688979 | Partridge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Craig Partridge (El Cerrito, California); Walter Clark Milliken (Dover, New Hampshire); David Patrick Mankins (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Verizon Corporate Services Group Inc. (Basking Ridge, New Jersey); Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| INVENTOR(S) | Craig Partridge (El Cerrito, California); Walter Clark Milliken (Dover, New Hampshire); David Patrick Mankins (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments of the invention reduce the probability of success of a DOS attack on a node receiving packets by decreasing the probability of random collisions of packets sent by a malicious user with those sent by honest users. The probability of random collisions may be reduced in one class of embodiments of the invention by supplementing the identification field of the IP header of each transmitted packet with at least one bit from another field of the header. The probability of random collisions may be reduced in another class of embodiments of the invention by ensuring that packets sent from a transmitting IPsec node to a receiving IPsec node are not fragmented. |
| FILED | Friday, March 04, 2011 |
| APPL NO | 13/040905 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08684187 | Buschmann |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne E. Buschmann (Boulder, Colorado) |
| ASSIGNEE(S) | Eltron Research and Development, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Wayne E. Buschmann (Boulder, Colorado) |
| ABSTRACT | A polyamide membrane including reaction product of an anhydrous solution comprising an anhydrous solvent, at least one polyfunctional secondary amine and a pre-polymer deposition catalyst, and an anhydrous, organic solvent solution comprising a polyfunctional aromatic amine-reactive reactant having one ring. A composite semipermeable membrane including the polyamide membrane on a porous support. |
| FILED | Monday, March 05, 2012 |
| APPL NO | 13/412538 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/500.380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685286 | Svoboda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vojtech Svoboda (Huntsville, Alabama); Jianjun Wei (Huntsville, Alabama); Sameer Singhal (Huntsville, Alabama) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Vojtech Svoboda (Huntsville, Alabama); Jianjun Wei (Huntsville, Alabama); Sameer Singhal (Huntsville, Alabama) |
| ABSTRACT | The present disclosure provides an electrode including an electrically conductive ink deposited thereon comprising: a nano-scale conducting material; a binding agent; and an enzyme; wherein said ink is essentially solvent free. In one embodiment, the ink includes at least one of a mediator, a cross-linking agent and a substrate as well. In one further embodiment, the electrode provided herein is used in a battery, fuel cell or sensor. |
| FILED | Wednesday, June 08, 2011 |
| APPL NO | 13/155752 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688036 | Parkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John W. Parkins (Ithaca, New York); Mike Bartos (Groton, New York) |
| ASSIGNEE(S) | Red Tail Hawk Corporation (Ithaca, New York) |
| INVENTOR(S) | John W. Parkins (Ithaca, New York); Mike Bartos (Groton, New York) |
| ABSTRACT | A wireless communications headset system for double hearing protection systems that eliminates the problems associated with typical wireless communications systems. The system employs a magnetic-field coupled wireless link from a loop transmitter to a magnetic field receiver. Current through the transmitter wire loops generates magnetic flux which passes through a communications earplug. The earplug has a receiver for converting the magnetic flux to electrical voltage, and this voltage is used to drive a speaker within the earplug. The transmitter can be easily installed into aviation headsets. The loop transmitter has an open center sized so that it fits around the pinna of the human ear enabling a close position to the communications earplug. This close position is advantageous if an efficient system is desired. |
| FILED | Friday, August 10, 2007 |
| APPL NO | 11/837129 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/41.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08685672 | Grabber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John H. Grabber (Mazomanie, Wisconsin); John Ralph (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | John H. Grabber (Mazomanie, Wisconsin); John Ralph (Madison, Wisconsin) |
| ABSTRACT | A method of manufacturing modified lignin and the resulting non-natural modified lignin product in which a lignin-producing polymerization reaction is performed using a polymerizable monomer having the structure: wherein at least one of the polymerizable monomers is incorporated into the resulting lignin. |
| FILED | Tuesday, April 19, 2011 |
| APPL NO | 13/090206 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/72 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08686218 | Romaine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | C. Peter Romaine (State College, Pennsylvania); Carl David Schlagnhaufer (Julian, Pennsylvania); Benjamin Michael Woolston (Long Valley, New Jersey) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | C. Peter Romaine (State College, Pennsylvania); Carl David Schlagnhaufer (Julian, Pennsylvania); Benjamin Michael Woolston (Long Valley, New Jersey) |
| ABSTRACT | Disclosed is a new technology that enables the transgenic modification of a mushroom-forming fungus to confer a transgenic genotype and/or phenotype. According to the invention herein, one can manipulate the fruiting body of a fungus conferring an altered phenotype, but a wild-type genotype. The fruiting body itself is devoid of any cognate transgene, and Applicants have discovered a new mechanism of protein synthesis and accumulation in fungi and a technique to independently control the genotype and phenotype of the fruiting body. |
| FILED | Tuesday, April 12, 2011 |
| APPL NO | 13/640131 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 08686351 | Ouyang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); Robert Graham Cooks (West Lafayette, Indiana); Sandilya Venkata Garimella (West Lafayette, Indiana); Jason David Harper (Lafayette, Indiana); Nicholas Alan Charipar (Batavia, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for transferring ions for analysis. In certain embodiments, the invention provides a system for analyzing a sample including an ionizing source for converting molecules of a sample into gas phase ions in a region at about atmospheric pressure, an ion analysis device, and an ion transfer member operably coupled to a gas flow generating device, in which the gas flow generating device produces a laminar gas flow that transfers the gas phase ions through the ion transfer member to an inlet of the ion analysis device. |
| FILED | Tuesday, July 09, 2013 |
| APPL NO | 13/937913 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/282 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08688375 | Funk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Benjamin E. Funk (Silver Spring, Maryland); Amrit Bandyopadhyay (Greenbelt, Maryland); Eric A. Kohn (Washington, District of Columbia); Neil Goldsman (Takoma Park, Maryland); Carole A. Teolis (Glendale, Maryland); Gilmer L. Blankenship (Washington, District of Columbia) |
| ASSIGNEE(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
| INVENTOR(S) | Benjamin E. Funk (Silver Spring, Maryland); Amrit Bandyopadhyay (Greenbelt, Maryland); Eric A. Kohn (Washington, District of Columbia); Neil Goldsman (Takoma Park, Maryland); Carole A. Teolis (Glendale, Maryland); Gilmer L. Blankenship (Washington, District of Columbia) |
| ABSTRACT | The present invention is directed to methods and systems for locating and monitoring the status of people and moveable assets, such as first responders, including firefighters and other public service personnel, and their equipment both indoors and out. The invention can provide for locating and monitoring the status of people and assets in environments where GPS systems do not operate, or where operation is impaired or otherwise limited. The system and method uses inertial navigation to determine the location, motion and orientation of the personnel or assets and communicates with an external monitoring station to receive requests for location, motion orientation and status information and to transmit the location, motion orientation and status information to the monitoring station. The system and method can include storing the location, motion and orientation data as well as status data, in the event that the communication system is unable to communicate with and transmit information to the monitoring station, the system will wait until communication is restored and transmit the status information to the monitoring station to update the location, motion orientation and status information for the person or asset. |
| FILED | Thursday, May 31, 2007 |
| APPL NO | 11/756412 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/495 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08685340 | Hasan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leila Hasan (Brookline, Massachusetts); John Linton (Lincoln, Massachusetts); Colin J. H. Brenan (Marblehead, Massachusetts) |
| ASSIGNEE(S) | Life Technologies Corporation (Carlsbad, California) |
| INVENTOR(S) | Leila Hasan (Brookline, Massachusetts); John Linton (Lincoln, Massachusetts); Colin J. H. Brenan (Marblehead, Massachusetts) |
| ABSTRACT | A liquid dispenser for a microfluidic assay system is described. The dispenser includes at least one transfer pin for transferring a microfluidic sample of liquid to a target receptacle. A pin tip at one end of the transfer pin is structured to cooperate with an opening in the target receptacle. The tip uses capillary action to transfer the sample from the pin to the receptacle. |
| FILED | Thursday, April 17, 2008 |
| APPL NO | 12/148416 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 08685237 | Littman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Howard Littman (Niskayuna, New York); Joel L. Plawsky (Albany, New York); John D. Paccione (Voorheesville, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Howard Littman (Niskayuna, New York); Joel L. Plawsky (Albany, New York); John D. Paccione (Voorheesville, New York) |
| ABSTRACT | An improved draft tube spout fluid bed (DTSFB) mixing, handling, conveying, and treating apparatus and systems, and methods for operating are provided. The apparatus and systems can accept particulate material and pneumatically or hydraulically conveying the material to mix and/or treat the material. In addition to conveying apparatus, a collection and separation apparatus adapted to receive the conveyed particulate material is also provided. The collection apparatus may include an impaction plate against which the conveyed material is directed to improve mixing and/or treatment. The improved apparatus are characterized by means of controlling the operation of the pneumatic or hydraulic transfer to enhance the mixing and/or reacting by controlling the flow of fluids, for example, air, into and out of the apparatus. The disclosed apparatus may be used to mix particulate material, for example, mortar; react fluids with particulate material; coat particulate material, or simply convey particulate material. |
| FILED | Friday, November 06, 2009 |
| APPL NO | 12/614165 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Liquid purification or separation 210/153 |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 08688463 | Mills |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven E. Mills (Annandale, Virginia) |
| ASSIGNEE(S) | The United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Steven E. Mills (Annandale, Virginia) |
| ABSTRACT | Disclosed is a system, method, and medium for automatically analyzing response pieces. The system may scan the response piece, identify the response piece, and generate an image from the response piece. The system also processes the image. Processing the image may include determining response piece identification information and sending the response piece identification information to an accounting system to update an account associated with the response piece identification information. Processing the image may also include reading information from the response piece. |
| FILED | Wednesday, October 05, 2005 |
| APPL NO | 11/242924 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08685219 | Schlenoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph B. Schlenoff (Tallahassee, Florida); Timothy W. Graul (Groton, Connecticut) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Joseph B. Schlenoff (Tallahassee, Florida); Timothy W. Graul (Groton, Connecticut) |
| ABSTRACT | An apparatus for capillary zone electrophoresis includes a polyelectrolyte multilayer positioned in a capillary tube for analytical separations of macromolecules. The capillary comprises a passage defined by passage walls comprising fused silica and the polyelectrolyte multilayer positioned within the passage. The polyelectrolyte multilayer comprises layers with alternating charge. The apparatus includes a power supply having a positive electrode and a negative electrode for generating an electric field therebetween and a sensor positioned adjacent the passage for sensing macromolecules. |
| FILED | Thursday, October 18, 2007 |
| APPL NO | 11/874233 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08685406 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David H. Walker (Galveston, Texas); Sunil Thomas (Dickinson, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | David H. Walker (Galveston, Texas); Sunil Thomas (Dickinson, Texas) |
| ABSTRACT | The present invention provides an isolated and purified heat shock protein 60 (Hsp60) peptide having the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a vaccine against Ehrlichia comprising a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to an antibody directed against a peptide homologous to the amino acid sequence of SEQ ID NO:2. The instant invention is also directed to a method of determining whether a subject is infected with Ehrlichia, comprising the steps of: contacting a sample from a subject with the antibody described herein; and detecting a resulting antibody reaction, wherein a positive reaction indicates the subject is infected with Ehrlichia. |
| FILED | Wednesday, November 10, 2010 |
| APPL NO | 12/927220 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/190.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
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THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 01, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140401.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page