FedInvent™ Patents

Patent Details for Tuesday, April 08, 2014 

This page was updated on Monday, March 27, 2023 at 03:58 AM GMT

Department of Health and Human Services (HHS) 

US 08690865 Prausnitz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Mark R. Prausnitz (Atlanta, Georgia);  Mark G. Allen (Atlanta, Georgia);  Jung-Hwan Park (Smyrna, Georgia);  Yong-Kyu Yoon (Smyrna, Georgia);  Jin-Woo Park (Suwanee, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Mark R. Prausnitz (Atlanta, Georgia);  Mark G. Allen (Atlanta, Georgia);  Jung-Hwan Park (Smyrna, Georgia);  Yong-Kyu Yoon (Smyrna, Georgia);  Jin-Woo Park (Suwanee, Georgia)
ABSTRACT The present invention comprises methods and devices for thermal treatment of a barrier to increase the permeability of the barrier. One form of increasing the permeability of the barrier comprises forming micropores which may be used for administration of active agents across the barrier, or may be used for sampling or collecting fluids, or may be used for detecting, measuring or determining analytes, or may be used for monitoring of physiological or other conditions. Devices of the present invention may comprise microheaters that are activated by inductive or ohmic heating power supply components.
FILED Tuesday, May 31, 2005
APPL NO 11/597969
ART UNIT 3739 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
66/28
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691010 Hansen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Carl L. Hansen (Pasadena, California);  Morten Sommer (Copenhagen NV, Denmark);  Stephen R. Quake (San Marino, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Carl L. Hansen (Pasadena, California);  Morten Sommer (Copenhagen NV, Denmark);  Stephen R. Quake (San Marino, California)
ABSTRACT The use of microfluidic structures enables high throughput screening of protein crystallization. In one embodiment, an integrated combinatoric mixing chip allows for precise metering of reagents to rapidly create a large number of potential crystallization conditions, with possible crystal formations observed on chip. In an alternative embodiment, the microfluidic structures may be utilized to explore phase space conditions of a particular protein crystallizing agent combination, thereby identifying promising conditions and allowing for subsequent focused attempts to obtain crystal growth.
FILED Friday, April 15, 2011
APPL NO 13/087697
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/68
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691088 Ivanov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Alexander R. Ivanov (East Boston, Massachusetts);  Li Zang (Malden, Massachusetts);  Barry L. Karger (Newton, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Alexander R. Ivanov (East Boston, Massachusetts);  Li Zang (Malden, Massachusetts);  Barry L. Karger (Newton, Massachusetts)
ABSTRACT A method of preparing an ultra-nanoscale-LC monolithic separation medium for use in capillary columns, or channels in microfabricated devices (microchips), and capillaries prepared by the method are disclosed. The application of moderate positive pressure to both ends of the capillary during the monolith polymerization process permits the preparation of monolithic capillary columns having very low i.d., e.g., 25 μm and smaller, with enhanced mass transfer properties and low back pressures, and excellent column-to-column reproducibility of retention times.
FILED Friday, April 21, 2006
APPL NO 11/409415
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/198.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691151 Kovac et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Joseph Kovac (Fort Worth, Texas);  Joel Voldman (Belmont, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Joseph Kovac (Fort Worth, Texas);  Joel Voldman (Belmont, Massachusetts)
ABSTRACT This invention provides an apparatus for particle sorting, particle patterning, and methods of using the same. The sorting or patterning is opto-fluidics based, in that particles are applied to individual chambers in the device, detection and/or analysis of the particles is carried out, such that a cell or population whose removal or conveyance is desired is defined, and the cell or population is removed or conveyed via application of an optical force and flow-mediated conveyance or removal of the part.
FILED Monday, August 27, 2007
APPL NO 12/439650
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/73
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US 08691184 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Shaomeng Wang (Saline, Michigan);  Haibin Zhou (Ann Arbor, Michigan);  Jianfang Chen (Ann Arbor, Michigan);  Angelo Aguilar (Ann Arbor, Michigan);  Jennifer L. Meagher (Plymouth, Michigan);  Duxin Sun (Ann Arbor, Michigan);  Chao-Yie Yang (Ann Arbor, Michigan);  Liu Liu (Ann Arbor, Michigan);  Longchuan Bai (Ann Arbor, Michigan);  Donna McEachem (Ann Arbor, Michigan);  Jeanne Stuckey (Fenton, Michigan);  Xiaoqin Li (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Shaomeng Wang (Saline, Michigan);  Haibin Zhou (Ann Arbor, Michigan);  Jianfang Chen (Ann Arbor, Michigan);  Angelo Aguilar (Ann Arbor, Michigan);  Jennifer L. Meagher (Plymouth, Michigan);  Duxin Sun (Ann Arbor, Michigan);  Chao-Yie Yang (Ann Arbor, Michigan);  Liu Liu (Ann Arbor, Michigan);  Longchuan Bai (Ann Arbor, Michigan);  Donna McEachem (Ann Arbor, Michigan);  Jeanne Stuckey (Fenton, Michigan);  Xiaoqin Li (Ann Arbor, Michigan)
ABSTRACT Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed.
FILED Tuesday, January 24, 2012
APPL NO 13/356763
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691186 Pomper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Martin G. Pomper (Baltimore, Maryland);  Chetan Bettegowda (Charlotte, North Carolina);  Catherine Foss (Baltimore, Maryland);  Shibin Zhou (Owings Mills, Maryland);  Kenneth Kinzler (Baltimore, Maryland);  Bert Vogelstein (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Martin G. Pomper (Baltimore, Maryland);  Chetan Bettegowda (Charlotte, North Carolina);  Catherine Foss (Baltimore, Maryland);  Shibin Zhou (Owings Mills, Maryland);  Kenneth Kinzler (Baltimore, Maryland);  Bert Vogelstein (Baltimore, Maryland)
ABSTRACT The instant invention provides a method for diagnosing an infection in a subject by administering to the subject a compound suitable for imaging which binds to a thymidine kinase present in the infecting organism, and obtaining an image of the subject to determine the presence and location of the compound, wherein a localization of the compound is indicative that the subject has an infection.
FILED Tuesday, August 28, 2012
APPL NO 13/596632
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/1.890
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691188 Marchese et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Adriano Marchese (Westchester, Illinois);  Rohit Malik (Forest Park, Illinois)
ASSIGNEE(S) Loyola University Chicago (Maywood, Illinois)
INVENTOR(S) Adriano Marchese (Westchester, Illinois);  Rohit Malik (Forest Park, Illinois)
ABSTRACT Methods of utilizing the arrestin-2/sTAM-1 complex as a therapeutic target. The methods include treating cells of a living organism to mediate an interaction between arrestin-2 and STAM-1 adapter protein molecules, wherein the interaction is characterized by the arrestin-2 adapter protein molecule directly binding to the STAM-2 adapter protein molecule. Pharmacological agents can be identified for therapeutic uses by determining whether the pharmacological agent disrupts the interaction between the arrestin-2 and STAM-1 adapter protein molecules.
FILED Wednesday, May 25, 2011
APPL NO 13/115666
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.200
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US 08691203 Bettinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
APPLICANT(S) Christopher J. Bettinger (Palo Alto, California);  Joost P. Bruggeman (Schorl, Netherlands);  Lino Da Silva Ferreira (Coimbra, Portugal);  Jeffrey M. Karp (Chestnut Hill, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Christiaan Nijst (Amsterdam, Netherlands);  Andreas Zumbuehl (Nyon, Switzerland);  Jason Burdick (Philadelphia, Pennsylvania);  Sonia J. Kim (West Nyack, New York)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Christopher J. Bettinger (Palo Alto, California);  Joost P. Bruggeman (Schorl, Netherlands);  Lino Da Silva Ferreira (Coimbra, Portugal);  Jeffrey M. Karp (Chestnut Hill, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Christiaan Nijst (Amsterdam, Netherlands);  Andreas Zumbuehl (Nyon, Switzerland);  Jason Burdick (Philadelphia, Pennsylvania);  Sonia J. Kim (West Nyack, New York)
ABSTRACT The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers.
FILED Friday, March 23, 2012
APPL NO 13/428869
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/78.60
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691230 Baron et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Margaret H. Baron (New York, New York);  Sarah M. Farrington (Cambridge, Massachusetts);  Maria Belaoussoff (Cambridge, Massachusetts)
ASSIGNEE(S) The President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Margaret H. Baron (New York, New York);  Sarah M. Farrington (Cambridge, Massachusetts);  Maria Belaoussoff (Cambridge, Massachusetts)
ABSTRACT This application pertains to methods and compositions that modulate proliferation and/or differentiation of undifferentiated mesodermally-derived cells so as to have an effect on at least one of vascular growth and hematopoiesis.
FILED Wednesday, June 27, 2012
APPL NO 13/534833
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/139.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691276 Badylak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Stephen F. Badylak (Pittsburgh, Pennsylvania);  Donald Freytes (Pittsburgh, Pennsylvania)
ABSTRACT Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
FILED Monday, November 26, 2012
APPL NO 13/684830
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/484
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691501 Gordon et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Leslie B. Gordon (Foxboro, Massachusetts);  Francis S. Collins (Rockville, Maryland);  Thomas Glover (Ypsilanti, Michigan);  Michael W. Glynn (Darien, Connecticut);  Brian C. Capell (Rumson, New Jersey);  Adrienne D. Cox (Chapel Hill, North Carolina);  Channing J. Der (Chapel Hill, North Carolina)
ASSIGNEE(S) Progeria Research Foundation, Inc. (Peabody, Massachusetts);  The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  The Universitry of North Carolina at Chapel Hill (Chapel Hill, North Carolina);  The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Leslie B. Gordon (Foxboro, Massachusetts);  Francis S. Collins (Rockville, Maryland);  Thomas Glover (Ypsilanti, Michigan);  Michael W. Glynn (Darien, Connecticut);  Brian C. Capell (Rumson, New Jersey);  Adrienne D. Cox (Chapel Hill, North Carolina);  Channing J. Der (Chapel Hill, North Carolina)
ABSTRACT Although it can be farnesylated, mutant lamin A expressed in Hutchinson Gilford Progeria Syndrome cannot be defarnesylated; the characteristic mutation causes deletion of a cleavage site necessary for binding the protease ZMPSTE24 and effecting defarnesylation. The result is an aberrant farnesylated protein (“progerin”) that alters normal lamin A function as a dominant negative, and assumes its own aberrant function through its association with the nuclear membrane. Retention of farnesylation, and potentially other abnormal properties of progerin and other abnormal lamin gene protein products, produces disease. Farnesyltransferase inhibitors (FTIs) will inhibit formation of progerin, cause a decrease in lamin A protein, and/or an increase prelamin A protein. Decreasing the amount of aberrant protein improves cellular effects caused by and progerin expression. Similarly, treatment with FTIs should improve disease status in progeria and other laminopathies. In addition, elements of atherosclerosis and aging in non-laminopathy individuals will improve after treatment with FTIs.
FILED Monday, August 06, 2012
APPL NO 13/567432
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
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US 08691502 Kupper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Thomas S. Kupper (Weston, Massachusetts);  Luzheng Liu (Vernon Hills, Illinois);  Rachael A. Clark (Belmont, Massachusetts)
ASSIGNEE(S) TremRx, Inc. (Boston, Massachusetts)
INVENTOR(S) Thomas S. Kupper (Weston, Massachusetts);  Luzheng Liu (Vernon Hills, Illinois);  Rachael A. Clark (Belmont, Massachusetts)
ABSTRACT Attenuated, replication-deficient viruses such as vaccinia viruses are used to deliver an exogenous viral, bacterial, parasitic or tumor antigen to an epidermal tissue such as the skin, lungs or gastrointestinal tract, which has been mechanically disrupted, in an amount effective to elicit or stimulate a cell mediated immune response. The epidermal tissue may be mechanically disrupted by a device such as a scarification needle or an abrader device. The epidermis may be mechanically disrupted prior to, at the same time, or immediately after the administration of the vaccine. The vaccine can be used to induce immunity against a pathogen, such as a virus, bacteria, or parasite, or against a cancer in a subject that has or is at risk of developing cancer. In some embodiments a co-stimulatory molecule, a growth factor, an adjuvant and/or a cytokine is administered before, with or after the viral vaccine. In some embodiments, the co-stimulatory molecule is co-expressed with the antigen by the virus.
FILED Monday, May 02, 2011
APPL NO 13/099235
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/5
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US 08691519 Gan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The J. David Gladstone Institutes (San Francisco, California)
ASSIGNEE(S) The J. David Gladstone Institutes (San Francisco, California)
INVENTOR(S) Li Gan (Burlingame, California);  Lennart Mucke (San Francisco, California)
ABSTRACT The present invention provides methods for reducing the level of amyloid beta protein in a cell or tissue, the methods generally involving contacting the cell or tissue with an agent that reduces cystatin C levels and/or activity. The present invention provides methods for treating Alzheimer's disease (AD), and methods for treating cerebral angiopathy, in an individual, the methods generally involving administering to an individual having AD a therapeutically effective amount of an agent that reduces cystatin C levels and/or activity. The present invention further provides methods for identifying an agent that reduces cystatin C levels and/or activity.
FILED Tuesday, March 19, 2013
APPL NO 13/847092
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/23
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US 08691542 Guilak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Farshid Guilak (Durham, North Carolina);  Bradley T. Estes (Durham, North Carolina);  Franklin Thomas Moutos (Raleigh, North Carolina)
ASSIGNEE(S) Cytex Therapeutics, Inc. (Durham, North Carolina)
INVENTOR(S) Farshid Guilak (Durham, North Carolina);  Bradley T. Estes (Durham, North Carolina);  Franklin Thomas Moutos (Raleigh, North Carolina)
ABSTRACT The presently disclosed subject matter generally relates to methods and systems for facilitating the growth and differentiation of adipose-derived stem cells for laboratory and therapeutic applications. The cells can be employed alone or in conjunction with unique biologically-compatible scaffold structures to generate differentiated tissues and structures, both in vitro and in vivo. The presently disclosed subject matter further relates to methods of forming and using improved tissue engineered scaffolds that can be used as substrates to facilitate the growth and differentiation of cells.
FILED Monday, September 11, 2006
APPL NO 12/083619
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/180
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US 08691556 Brophy et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Colleen M. Brophy (Nashville, Tennessee);  Padmini Komalavilas (Nashville, Tennessee);  Joyce Cheung-Flynn (Nashville, Tennessee);  Kyle M. Hocking (Nashville, Tennessee);  Susan S. Eagle (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Colleen M. Brophy (Nashville, Tennessee);  Padmini Komalavilas (Nashville, Tennessee);  Joyce Cheung-Flynn (Nashville, Tennessee);  Kyle M. Hocking (Nashville, Tennessee);  Susan S. Eagle (Nashville, Tennessee)
ABSTRACT The leading cause of graft failure is the subsequent development of intimal hyperplasia, which represents a response to injury that is thought to involve smooth muscle proliferation, migration, phenotypic modulation, and extracellular matrix (ECM) deposition. Surgical techniques typically employed for vein harvest—stretching the vein, placing the vein in low pH, solutions, and the use of toxic surgical skin markers—are shown here to cause injury. The invention therefore provides for non-toxic surgical markers than also protect against stretch-induced loss of functional viability, along with other additives. Devices and compositions for reducing physical stress or protecting from the effects flowing therefrom, also are provided.
FILED Wednesday, December 08, 2010
APPL NO 12/963375
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/284.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691564 Benes
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Helen Benes (Little Rock, Arkansas)
ASSIGNEE(S) The Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S) Helen Benes (Little Rock, Arkansas)
ABSTRACT The present invention provides an insect expression system that may be used to provide biological control of pest insects and control transmission of infectious diseases transmitted to the human population by insects.
FILED Friday, June 22, 2012
APPL NO 13/531101
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
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US 08691567 Harper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Scott Harper (Iowa City, Iowa);  Beverly L. Davidson (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Scott Harper (Iowa City, Iowa);  Beverly L. Davidson (Iowa City, Iowa)
ABSTRACT The present invention is directed to nucleic acid molecules containing a loop sequence designed to circumvent exportin-5 mediated export, and methods using these novel molecules.
FILED Thursday, June 21, 2012
APPL NO 13/529925
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
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US 08691570 Kalinski
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Pawel Kalinski (Wexford, Pennsylvania)
ASSIGNEE(S)
INVENTOR(S) Pawel Kalinski (Wexford, Pennsylvania)
ABSTRACT The present invention discloses novel dendritic cell maturation-inducing cytokine cocktails, and methods for inducting type-1 polarized dendritic cells in serum-free conditions which enhance the desirable properties of DC1s generated in serum-supplemented cultures. The invention further discloses methods and systems using IFNγ and other ligands of the IFNγ receptor, in combination with IFNα (or other type I interferons), poly I:C, and other IFNα (and IFNβ) inducers to enhance the IL-12-producing properties of dendritic cells. More specifically, the present invention discloses type-1 polarized dendritic cells that have a unique combination of a fully-mature status and an elevated, instead of “exhausted”, ability to produce IL-12p70. allows for the generation of fully-mature DC1s in serum-free AIM-V medium. The invention discloses systems that use the foregoing products and methods to facilitate the clinical application of DC1-based vaccines and the identification of novel factors involved in the induction of Th1 and CTL responses by DC1.
FILED Friday, January 25, 2013
APPL NO 13/750850
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/372
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US 08691572 Feinberg
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Mark W. Feinberg (Newton, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Mark W. Feinberg (Newton, Massachusetts)
ABSTRACT The present invention provides methods and compositions for treating chronic inflammatory disease in a subject and associated pharmaceutical compositions, medical devices and systems.
FILED Monday, May 11, 2009
APPL NO 12/464037
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/375
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US 08691582 Halden
FUNDED BY
Department of Defense (DOD)
Environmental Security Technology Certification Program (ESTCP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Rolf U. Halden (Phoenix, Arizona)
ASSIGNEE(S) Arizona Board of Regents (Scottsdale, Arizona)
INVENTOR(S) Rolf U. Halden (Phoenix, Arizona)
ABSTRACT A method for in situ monitoring within a specified environment. The method includes locating a housing in a well, wherein a set of pumps and a plurality of test beds are inserted. Each of the set of pumps are controlled by signals from the control system to push water from each pump into one of the plurality of separate test beds where, after flowing through each of the test beds, effluent flows into an effluent storage device.
FILED Monday, November 19, 2012
APPL NO 13/681125
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/28
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US 08691585 O'Connor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) John F. O'Connor (New Rochelle, New York);  Galina I. Kovalevskaya (Bronx, New York);  Steven Birken (Dumont, New Jersey)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) John F. O'Connor (New Rochelle, New York);  Galina I. Kovalevskaya (Bronx, New York);  Steven Birken (Dumont, New Jersey)
ABSTRACT The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early pregnancy associated molecular isoforms of human chorionic gonadotropin (hCG) in a sample. The present invention also provides a diagnostic kit for determining the amount of early pregnancy associated hCG in a sample. The present invention additionally provides an antibody which specifically binds to an early pregnancy associated molecular isoform of human chorionic gonadotropin. Finally, the present invention provides methods for detecting trophoblast or non-trophoblast malignancy in a sample.
FILED Wednesday, June 01, 2011
APPL NO 13/150791
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/65
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US 08691588 Park et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) Seung-min Park (Albany, California);  Yun Suk Huh (Daejeon, South Korea);  David Erickson (Ithaca, New York);  Harold G. Craighead (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Seung-min Park (Albany, California);  Yun Suk Huh (Daejeon, South Korea);  David Erickson (Ithaca, New York);  Harold G. Craighead (Ithaca, New York)
ABSTRACT A method is provided for fabricating a nanochannel. The method comprises providing a microchannel and controlling collapse of the microchannel so that it collapses to form a nanochannel of desired dimensions. The method employs a collapsible, flexible material such as the elastomer polydimethylsiloxane (PDMS) to form the nanochannel. A master is provided that is configured to have geometric conditions that promote a desired frequency of microchannel collapse. A collapsible material having a stiffness that also promotes a desired frequency of microchannel collapse is molded on the master. The molded collapsible material is removed from the master and bonded to a base, thereby forming the microchannel, which then collapses (or is collapsed) to form the nanochannel of desired dimensions. Nanofluidic and microfluidic devices comprising complex nanochannel structures and micro to nanochannel transitions are also provided.
FILED Friday, August 20, 2010
APPL NO 13/391508
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/94
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US 08691592 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Zongyuan Chen (Claymont, Delaware);  Haim H. Bau (Swarthmore, Pennsylvania);  Michael Mauk (Greenville, Delaware);  Xianbo Qiu (Philadelphia, Pennsylvania);  Jason Kwa (Wellesley, Massachusetts)
ASSIGNEE(S) The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Zongyuan Chen (Claymont, Delaware);  Haim H. Bau (Swarthmore, Pennsylvania);  Michael Mauk (Greenville, Delaware);  Xianbo Qiu (Philadelphia, Pennsylvania);  Jason Kwa (Wellesley, Massachusetts)
ABSTRACT Disclosed are mechanically-actuated devices for transporting fluids within a microfluidic circuit and performing diagnostic operations on a sample. Also disclosed are related methods for performing sample analysis effected by the motion of an actuator proximate to a microfluidic system.
FILED Friday, December 14, 2007
APPL NO 12/515616
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/180
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US 08691729 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) David R. Liu (Lexington, Massachusetts);  Matthew William Kanan (Palo Alto, California);  Mary M. Rozenman (New York, New York)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Lexington, Massachusetts);  Matthew William Kanan (Palo Alto, California);  Mary M. Rozenman (New York, New York)
ABSTRACT A novel reaction discovery system that does not depend on DNA duplex formation is provided. The advantages of this system include exploring reactions conditions not possible where DNA hybridization is required. For example, the inventive reaction discovery system allows for reaction conditions using organic solvents, higher temperatures, and water-insoluble reagents, catalysts, and ligands. The invention also provides single-stranded oligonucleotide templates with substrate pairs covalently attached and methods of screening for reaction conditions that result in a direct covalent bond between the substrates. Kits are also provided for practicing this novel reaction discovery system.
FILED Wednesday, January 09, 2008
APPL NO 11/971642
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Combinatorial chemistry technology: Method, library, apparatus
56/11
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US 08691761 Rivier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Jean E. F. Rivier (La Jolla, California);  Judit Erchegyi (San Diego, California);  Jean Claude Reubi (Switzerland, Switzerland);  Helmut R. Maecke (Basel, Switzerland)
ASSIGNEE(S)
INVENTOR(S) Jean E. F. Rivier (La Jolla, California);  Judit Erchegyi (San Diego, California);  Jean Claude Reubi (Switzerland, Switzerland);  Helmut R. Maecke (Basel, Switzerland)
ABSTRACT The invention is directed to somatostatin analogs which are receptor antagonists of the somatostatin receptor, including receptor-selective antagonists, especially sst2-selective antagonists. Related compounds and compositions are included, including antagonists complexed with or conjugated to radioactive nuclides. The antagonists of the invention are useful in diagnosing and treating neoplastic and non-neoplastic mammalian diseases; such methods, and kits, are encompassed.
FILED Wednesday, April 16, 2008
APPL NO 12/104318
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691762 Buxbaum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Joseph Buxbaum (New York, New York);  Takeshi Sakurai (New York, New York);  Ozlem Gunal (New York, New York)
ASSIGNEE(S) Mount Sinai School of Medicine (New York, New York)
INVENTOR(S) Joseph Buxbaum (New York, New York);  Takeshi Sakurai (New York, New York);  Ozlem Gunal (New York, New York)
ABSTRACT Methods and assays are disclosed for treating subjects with 22q13 deletion syndrome or SHANK3 deletion or duplication, mutation or reduced expression, where the methods comprise administering to the subject insulin-like growth factor 1 (IGF-1), IGF-1-derived peptide or analog, growth hormone, an AMPAkine, a compound that directly or indirectly enhances glutamate neurotransmission, including by inhibiting inhibitory (most typically GABA) transmission, or an agent that activates the growth hormone receptor or the insulin-like growth factor 1 (IGF-1) receptor, or a downstream signaling pathway thereof.
FILED Wednesday, March 21, 2012
APPL NO 13/425633
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/8.600
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US 08691764 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Zhiquan Zhang (Durham, North Carolina);  Basil Rigas (Old Field, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Zhiquan Zhang (Durham, North Carolina);  Basil Rigas (Old Field, New York)
ABSTRACT The present invention provides a method for inhibiting NF-κB activity in a subject, the method comprising providing an agent capable of inducing expression of annexin 1, whereby said agent induces expression of annexin 1 and whereby said induced expression of annexin 1 inhibits NF-κB activity. Also provided are annexin 1 mimetics capable of binding to NF-κB and pharmaceutical compositions of such inducing and mimetic agents.
FILED Friday, March 28, 2008
APPL NO 12/593550
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/12.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691766 Fallon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Justin R. Fallon (Providence, Rhode Island);  Beth A. McKechnie (North Attleboro, Massachusetts);  Michael Rafii (San Diego, California);  Hilliary Creely (Providence, Rhode Island);  Mark A. Bowe (Damascus, Maryland);  Alison R. Amenta (Pawtucket, Rhode Island);  Mary Lynn Mercado (Robbinsville, New Jersey);  Hiroki Hagiwara (Tokyo, Japan)
ASSIGNEE(S) Brown University Research Foundation (Providence, Rhode Island)
INVENTOR(S) Justin R. Fallon (Providence, Rhode Island);  Beth A. McKechnie (North Attleboro, Massachusetts);  Michael Rafii (San Diego, California);  Hilliary Creely (Providence, Rhode Island);  Mark A. Bowe (Damascus, Maryland);  Alison R. Amenta (Pawtucket, Rhode Island);  Mary Lynn Mercado (Robbinsville, New Jersey);  Hiroki Hagiwara (Tokyo, Japan)
ABSTRACT The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders.
FILED Wednesday, February 08, 2012
APPL NO 13/368968
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/17.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691777 Arbiser
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Jack L. Arbiser (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Jack L. Arbiser (Atlanta, Georgia)
ABSTRACT The disclosure relates to methods of treating tuberous sclerosis in a subject, comprising administering a composition comprising an mTOR inhibitor and a tyrosine kinase inhibitor to a subject that is diagnosed with, suspected of, or exhibiting symptoms of cancer. In some embodiments, the cancer is tuberous sclerosis. In some embodiments, the mTOR inhibitor is sirolimus and the tyrosine kinase inhibitor is imatinib. In some embodiments, the disclosure relates to a composition comprising an mTOR inhibitor and a tyrosine kinase inhibitor. In some embodiments, the disclosure relates to a composition comprising sirolimus and imatinib.
FILED Wednesday, January 25, 2012
APPL NO 13/357920
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/31
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US 08691786 Rossi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) City of Hope (Duarte, California);  Integrated DNA Technologies, Inc. (Coralville, Iowa)
ASSIGNEE(S) City of Hope (Duarte, California);  Integrated DNA Technologies, Inc. (Coralville, Iowa)
INVENTOR(S) John J. Rossi (Alta Lorna, California);  Mark A. Behlke (Coralville, Iowa);  Dongho Kim (Los Angeles, California)
ABSTRACT The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as for treating diseases caused by the expression of the gene. More particularly, the invention is directed to compositions that contain double stranded RNA (“dsRNA”), and methods for preparing them, that are capable of reducing the expression of target genes in eukaryotic cells. The dsRNA has a first oligonucleotide sequence that is between 25 and about 30 nucleotides in length and a second oligonucleotide sequence that anneals to the first sequence under biological conditions. In addition, a region of one of the sequences of the dsRNA having a sequence length of at least 19 nucleotides is sufficiently complementary to a nucleotide sequence of the RNA produced from the target gene to trigger the destruction of the target RNA by the RNAi machinery.
FILED Thursday, January 24, 2013
APPL NO 13/749110
ART UNIT 1674 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 08691787 Iyer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Radhakrishnan P. Iyer (Shrewsbury, Massachusetts);  Seetharamaiyer Padmanabhan (Lexington, Massachusetts)
ASSIGNEE(S) Spring Bank Pharmaceuticals, Inc. (Milford, Massachusetts)
INVENTOR(S) Radhakrishnan P. Iyer (Shrewsbury, Massachusetts);  Seetharamaiyer Padmanabhan (Lexington, Massachusetts)
ABSTRACT The present invention discloses compounds of formula (I):
which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
FILED Monday, November 14, 2011
APPL NO 13/296221
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/48
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US 08691793 Prestwich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Glenn D. Prestwich (Salt Lake City, Utah);  Xiao Zheng Shu (Salt Lake City, Utah);  Yanchun Liu (Franklin, Tennessee)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Glenn D. Prestwich (Salt Lake City, Utah);  Xiao Zheng Shu (Salt Lake City, Utah);  Yanchun Liu (Franklin, Tennessee)
ABSTRACT Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking and methods of making and using thereof.
FILED Friday, July 15, 2011
APPL NO 13/184401
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/54
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US 08691799 Sebti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Said M. Sebti (Tampa, Florida);  Richard Jove (Duarte, California)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Said M. Sebti (Tampa, Florida);  Richard Jove (Duarte, California)
ABSTRACT The subject invention pertains to the treatment of tumors and cancerous tissues and the prevention of tumorigenesis and malignant transformation through the modulation of JAK/STAT3 intracellular signaling. The subject invention concerns pharmaceutical compositions containing cucurbitacin I, or a pharmaceutically acceptable salt or analog thereof. Another aspect of the invention concerns methods of inhibiting the growth of a tumor by administering a cucurbitacin I, or a pharmaceutically acceptable salt or analog thereof, to a patient, wherein the tumor is characterized by the constitutive activation of the JAK/STAT3 intracellular signaling pathway. The present invention further pertains to methods of moderating the JAK and/or STAT3 signaling pathways in vitro or in vivo using cucurbitacin I, or a pharmaceutically acceptable salt or analog thereof. Another aspect of the present invention concerns a method for screening candidate compounds for JAK and/or STAT3 inhibition and anti-tumor activity.
FILED Monday, August 15, 2011
APPL NO 13/209937
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/177
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US 08691801 Guzman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Esther A. Guzman (Fort Pierce, Florida);  Jacob D. Johnson (Silver Spring, Maryland);  Amy E. Wright (Fort Pierce, Florida)
ASSIGNEE(S) Florida Atlantic University Board of Trustees (Boca Raton, Florida)
INVENTOR(S) Esther A. Guzman (Fort Pierce, Florida);  Jacob D. Johnson (Silver Spring, Maryland);  Amy E. Wright (Fort Pierce, Florida)
ABSTRACT Manzamine compounds have been discovered to decrease cell dissociation and cell migration associated with the metastatic potential of cancer cells and a restoration of cancer cell susceptibility to agents, such as TRAIL, which can induce apoptosis. Specifically, Manzamine A has a formerly unrecognized utility in both blocking tumor cell invasion and tumor metastasis as well in restoring cancer cell susceptibility to standard chemotherapeutic agents which induce apoptosis and, therefore, has utility in treating cancer.
FILED Tuesday, July 17, 2012
APPL NO 13/550880
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/183
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US 08691830 Tavares et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) G1 Therapeutics, Inc. (Chapel Hill, North Carolina)
ASSIGNEE(S) G1 Therapeutics, Inc. (Chapel Hill, North Carolina)
INVENTOR(S) Francis X. Tavares (Durham, North Carolina);  Jay C. Strum (Hillsborough, North Carolina)
ABSTRACT Compounds of formulae I, II or III, and pharmaceutically acceptable salts thereof, are useful as CDK inhibitors.
FILED Wednesday, April 24, 2013
APPL NO 13/869594
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/265.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691861 Sinha et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Sukanto Sinha (San Francisco, California);  Tamie Jo Chilcote (San Francisco, California);  Joghee Raju Suresh (Bangalore, India);  Sriram Narasimhan (Bangalore, India)
ASSIGNEE(S) ActiveSite Pharmaceuticals, Inc. (San Francisco, California)
INVENTOR(S) Sukanto Sinha (San Francisco, California);  Tamie Jo Chilcote (San Francisco, California);  Joghee Raju Suresh (Bangalore, India);  Sriram Narasimhan (Bangalore, India)
ABSTRACT This invention provides new pharmaceutically useful compounds that are prodrugs of inhibitors of plasma kallikrein and methods and compositions for preventing or treating plasma kallikrein dependent diseases or conditions, such as diabetic macular edema or hemorrhagic stroke, by administering prodrugs of the formula:
FILED Thursday, April 12, 2012
APPL NO 13/445614
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/406
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691866 Iliopoulos et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Othon Iliopoulos (Cambridge, Massachusetts);  Michael Zimmer (Arlington, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Othon Iliopoulos (Cambridge, Massachusetts);  Michael Zimmer (Arlington, Massachusetts)
ABSTRACT The present invention is directed to HIF inhibitors and methods of preventing cell proliferation, reducing inflammation, and treating an angiogenic disease or disorders.
FILED Thursday, December 10, 2009
APPL NO 13/139058
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/438
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691876 Smith
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) FXS Ventures, LLC (Salem, New Hampshire)
ASSIGNEE(S) FXS Ventures, LLC (Salem, New Hampshire)
INVENTOR(S) Francis X. Smith (Salem, New Hampshire)
ABSTRACT The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula:
where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
FILED Thursday, April 25, 2013
APPL NO 13/870215
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/642
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691944 Clark et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Richard A. Clark (Poqnott, New York);  Xiang-Dong Ren (Malvern, Pennsylvania);  Fubao Lin (Stony Brook, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Richard A. Clark (Poqnott, New York);  Xiang-Dong Ren (Malvern, Pennsylvania);  Fubao Lin (Stony Brook, New York)
ABSTRACT Described herein are fragments of fibronectin and variants thereof that bind growth factors. Compositions containing such a fragment of fibronectin are therefore useful in sequestering growth factors, and complexes containing both a FN fragment and a bound, active growth factor can be used to deliver growth factors to a patient (e.g., to a wound on the patient's skin).
FILED Wednesday, October 04, 2006
APPL NO 12/089291
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691946 Sanford et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Isaac Gilliam Sanford (Durham, North Carolina);  Martyn Kerry Darby (Chapel Hill, North Carolina);  Jonathan Allen Hodges (Durham, North Carolina);  Shrikumar Ambujakshan Nair (Cary, North Carolina);  Yuchen Chen (Chapel Hill, North Carolina);  Paul Theodore Hamilton (Cary, North Carolina);  Ganesan Sathya (Cary, North Carolina);  Hanne Gron (Durham, North Carolina);  Michelle Steffen Jansen (Durham, North Carolina)
ASSIGNEE(S) Affinergy, LLC (Durham, North Carolina)
INVENTOR(S) Isaac Gilliam Sanford (Durham, North Carolina);  Martyn Kerry Darby (Chapel Hill, North Carolina);  Jonathan Allen Hodges (Durham, North Carolina);  Shrikumar Ambujakshan Nair (Cary, North Carolina);  Yuchen Chen (Chapel Hill, North Carolina);  Paul Theodore Hamilton (Cary, North Carolina);  Ganesan Sathya (Cary, North Carolina);  Hanne Gron (Durham, North Carolina);  Michelle Steffen Jansen (Durham, North Carolina)
ABSTRACT Compositions and methods for tissue repair are provided including cell binding peptides and growth factor binding peptides. The cell binding peptides bind to one or more of stem cells, fibroblasts, or endothelial cells. The growth factor binding peptides include platelet derived growth factor (PDGF) binding peptides and growth differentiation factor (GDF) binding peptides. The tissue for repair includes tendon, muscle, connective tissue, ligament, cardiac tissue, vascular tissue, or dermis. Implantable devices for tissue repair are provided to which the cell and growth factor binding peptides are attached, such as acellular extracellular matrix having attached binding peptide.
FILED Tuesday, May 17, 2011
APPL NO 13/109802
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691947 Xie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Zi-Jian Xie (Saline, Michigan);  Qiqi Ye (Toledo, Ohio);  Zhichuan Li (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Zi-Jian Xie (Saline, Michigan);  Qiqi Ye (Toledo, Ohio);  Zhichuan Li (Toledo, Ohio)
ABSTRACT This invention is based in part on the elucidation of new structural conformations and functions of the sodium/potassium adenosine triphosphate synthase (Na/K ATPase), and especially elucidation of new binding sites and interactions. The present invention provides practical applications of several surprising structural and functional relationships between Na/K ATPase and compounds which interact with Na/K ATPase. Disclosure of these structures and relationships provides insight and practical solutions to chemically affecting not only the Na/K ATPase interactions, but also regulators known to be upstream and downstream.
FILED Thursday, January 13, 2011
APPL NO 13/521871
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691948 Davidson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Beverly L. Davidson (Iowa City, Iowa);  Yong Hong Chen (Iowa City, Iowa)
ABSTRACT The present disclosure provides targeting peptides and vectors containing a sequence that encodes targeting peptides that deliver agents to the brain.
FILED Monday, October 15, 2012
APPL NO 13/652177
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/329
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US 08691960 Reitman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Zachary James Reitman (Durham, North Carolina);  Hai Yan (Chapel Hill, North Carolina);  Bryan Daehahn Choi (Durham, North Carolina);  John Howard Sampson (Durham, North Carolina)
ABSTRACT Described herein are compositions and methods for generating oxidoreductases for enantioselective reactions. Described herein are compositions and methods for generating neomorphic (R)-2-hydroxyacid dehydrogenases capable of enzymatically converting a 1-carboxy-2-ketoacid to a 1-carboxy-(R)-2-hydroxyacid, or the reverse reaction. Illustrative examples include (a) (R)-2-hydroxyadipate dehydrogenase and uses thereof for converting 2-oxoadipate to (R)-2-hydroxyadipate, or the reverse reaction; and (b) (R)-2-hydroxyglutarate dehydrogenase and uses thereof for converting 2-oxoglutarate to (R)-2-hydroxyglutarate, or the reverse reaction. Also described herein are compositions and methods for generating non-natural microbial organisms to enzymatically convert 2-oxoadipate to (E)-2-hexenedioate or adipate, or to enzymatically convert 2-oxoglutarate to (E)-2-pentenedioate or glutarate, or the respective reverse reactions.
FILED Wednesday, February 27, 2013
APPL NO 13/778167
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691961 Puffer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Bridget Puffer (Corning, New York);  Kimberly-Anne Mattia (Philadelphia, Pennsylvania)
ASSIGNEE(S) Integral Molecular, Inc. (Philadelphia, Pennsylvania)
INVENTOR(S) Bridget Puffer (Corning, New York);  Kimberly-Anne Mattia (Philadelphia, Pennsylvania)
ABSTRACT The present invention relates to the production and uses of flavivirus replicons and flavivirus particles and reporter virus particles. The present invention relates to the production and uses of chimeric and codon-optimized flavivirus virus replicons and flavivirus virus particles and reporter virus particles.
FILED Tuesday, November 09, 2010
APPL NO 12/942632
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.720
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691966 Kariko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Katalin Kariko (Rydal, Pennsylvania);  Drew Weissman (Wynnewood, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Katalin Kariko (Rydal, Pennsylvania);  Drew Weissman (Wynnewood, Pennsylvania)
ABSTRACT This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.
FILED Tuesday, August 14, 2012
APPL NO 13/585517
ART UNIT 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692052 Stevens et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sean Stevens (San Diego, California);  Andrew J. Murphy (Croton-on-Hudson, New York);  Richard Flavell (Guilford, Connecticut);  Elizabeth Eynon (New Haven, Connecticut);  Jorge Galan (New Haven, Connecticut);  Tim Willinger (New Haven, Connecticut);  Markus Manz (Zurich, Switzerland);  Anthony Rongvaux (New Haven, Connecticut);  George D. Yancopoulos (Yorktown Heights, New York)
ASSIGNEE(S) Regeneron Pharmaceuticals (Tarrytown, New York);  Yale University (New Haven, Connecticut);  Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland)
INVENTOR(S) Sean Stevens (San Diego, California);  Andrew J. Murphy (Croton-on-Hudson, New York);  Richard Flavell (Guilford, Connecticut);  Elizabeth Eynon (New Haven, Connecticut);  Jorge Galan (New Haven, Connecticut);  Tim Willinger (New Haven, Connecticut);  Markus Manz (Zurich, Switzerland);  Anthony Rongvaux (New Haven, Connecticut);  George D. Yancopoulos (Yorktown Heights, New York)
ABSTRACT A mouse with a humanization of the mIL-3 gene and the mGM-CSF gene, a knockout of a mRAG gene, and a knockout of a mII2rg subunit gene; and optionally a humanization of the TPO gene is described. A RAG/II2rg KO/hTPO knock-in mouse is described. A mouse engrafted with human hematopoietic stem cells (HSCs) that maintains a human immune cell (HIC) population derived from the HSCs and that is infectable by a human pathogen, e.g., S. typhi or M. tuberculosis is described. A mouse that models a human pathogen infection that is poorly modeled in mice is described, e.g., a mouse that models a human mycobacterial infection, wherein the mouse develops one or more granulomas comprising human immune cells. A mouse that comprises a human hematopoietic malignancy that originates from an early human hematopoietic cells is described, e.g., a myeloid leukemia or a myeloproliferative neoplasia.
FILED Friday, September 14, 2012
APPL NO 13/617472
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/18
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692187 Hunt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) Donald F. Hunt (Charlottesville, Virginia);  Joshua J. Coon (Madison, Wisconsin);  John Edward Philip Syka (Charlottesville, Virginia);  Jarod A. Marto (Wayland, Massachusetts)
ASSIGNEE(S) University of Virginia Patent Foundation (, None)
INVENTOR(S) Donald F. Hunt (Charlottesville, Virginia);  Joshua J. Coon (Madison, Wisconsin);  John Edward Philip Syka (Charlottesville, Virginia);  Jarod A. Marto (Wayland, Massachusetts)
ABSTRACT The present invention relates to a new method for fragmenting ions in a mass spectrometer through the use of electron transfer dissociation, and for performing sequence analysis of peptides and proteins by mass spectrometry. In the case of peptides, the invention promotes fragmentation along the peptide backbone and makes it possible to deduce the amino acid sequence of the sample, including modified amino acid residues, through the use of an RF field device.
FILED Friday, March 16, 2012
APPL NO 13/422812
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/282
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692998 Gratton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Enrico Gratton (San Clemente, California);  Alexander Dvornikov (Irvine, California);  Viera Crosignani (Pasadena, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Enrico Gratton (San Clemente, California);  Alexander Dvornikov (Irvine, California);  Viera Crosignani (Pasadena, California)
ABSTRACT An apparatus and method for in-depth fluorescence imaging using two-photon fluorescence imaging in turbid media. The apparatus includes a detector which can significantly enhance the use of a detection method that allows to efficiently collect scattered fluorescence photons from a wide area of the turbid sample. By using this detector it is possible to perform imaging of turbid samples, simulating brain tissue at depths up to 3 mm, where the two-photon induced fluorescence signal is too weak to be detected by previous means used in conventional two-photon microscopy. The detector separates the excitation and detection optics which allows a more efficient collection of fluorescence and enhancing the possible imaging depth.
FILED Wednesday, April 11, 2012
APPL NO 13/444696
ART UNIT 2453 — Computer Networks
CURRENT CPC
Optics: Measuring and testing
356/441
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US 08693629 Sgouros et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) George Sgouros (Ellicott City, Maryland);  Robert Hobbs (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) George Sgouros (Ellicott City, Maryland);  Robert Hobbs (Baltimore, Maryland)
ABSTRACT A computerized method and system for determining an optimum amount of Internal Radionuclide Therapy (IRT) and External Radiation Therapy (XRT) to administer, comprising: obtaining activity image information for an imaged object from a detector; running a Monte Carlo simulation for the activity image information to obtain absorbed dose-rate image information at multiple times; adding the absorbed dose-rate image information from each time to obtain IRT total absorbed dose image information; and utilizing the IRT total dose image information to obtain total dose image information that is equivalent to XRT dose image information in terms of dose-rate, wherein the IRT dose information is converted to equivalent XRT dose information without having to generate BED dose maps.
FILED Thursday, January 14, 2010
APPL NO 12/687670
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/65
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693742 Piestun et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Rafael Piestun (Golden, Colorado);  Sri Rama Prasanna Pavani (Pasadena, California);  Michael A. Thompson (Orange, California);  Julie S. Biteen (Menlo Park, California);  William E. Moerner (Los Altos, California)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Rafael Piestun (Golden, Colorado);  Sri Rama Prasanna Pavani (Pasadena, California);  Michael A. Thompson (Orange, California);  Julie S. Biteen (Menlo Park, California);  William E. Moerner (Los Altos, California)
ABSTRACT Embodiments of the present invention can resolve molecules beyond the optical diffraction limit in three dimensions. A double-helix point spread function can be used to in conjunction with a microscope to provide dual-lobed images of a molecule. Based on the rotation of the dual-lobed image, the axial position of the molecule can be estimated or determined. In some embodiments, the angular rotation of the dual-lobed imaged can be determined using a centroid fit calculation or by finding the midpoints of the centers of the two lobes. Regardless of the technique, the correspondence between the rotation and axial position can be utilized. A double-helix point spread function can also be used to determine the lateral positions of molecules and hence their three-dimensional location.
FILED Thursday, December 17, 2009
APPL NO 12/640834
ART UNIT 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693745 Izatt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Joseph A. Izatt (Raleigh, North Carolina);  Mingtao C. Zhao (Durham, North Carolina);  Anthony N. Kuo (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Joseph A. Izatt (Raleigh, North Carolina);  Mingtao C. Zhao (Durham, North Carolina);  Anthony N. Kuo (Durham, North Carolina)
ABSTRACT Methods and computer program products for quantitative three-dimensional (“3D”) image correction in optical coherence tomography. Using the methods and computer program products, index interface (refracting) surfaces from the raw optical coherence tomography (“OCT”) dataset from an OCT system can be segmented. Normal vectors or partial derivatives of the curvature at a refracting surface can be calculated to obtain a refracted image voxel. A new position of each desired refracted image voxel can be iteratively computed. New refracted corrected voxel positions to an even sampling grid can be interpolated to provide corrected image data. In some embodiments, clinical outputs from the corrected image data can be computed.
FILED Tuesday, May 04, 2010
APPL NO 12/799890
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694111 Roy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Arup Roy (Valencia, California);  Chunhong Zhou (Pasadena, California);  Kelly H. McClure (Simi Valley, California);  Matthew J. McMahon (Los Angeles, California);  Avraham I. Caspi (La Jolla, California);  Pishoy Maksy (Newport Beach, California);  Robert J. Greenberg (Los Angeles, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Arup Roy (Valencia, California);  Chunhong Zhou (Pasadena, California);  Kelly H. McClure (Simi Valley, California);  Matthew J. McMahon (Los Angeles, California);  Avraham I. Caspi (La Jolla, California);  Pishoy Maksy (Newport Beach, California);  Robert J. Greenberg (Los Angeles, California)
ABSTRACT A method of editing a video configuration file downloadable to or from a video processing unit of a fitting system for a visual prosthesis is shown. The visual prosthesis has a plurality of electrodes and the video configuration file defines mapping of a video signal captured from a camera of the visual prosthesis to an electrical signal for the electrodes. The editing controls a brightness map for an individual electrode or electrode groups, together with a temporal stimulation pattern to which an individual electrode or electrode groups are assigned. A related computer-operated system is also disclosed.
FILED Wednesday, May 02, 2012
APPL NO 13/462646
ART UNIT 3766 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/53
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694114 Churchill
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Tyler Hale Churchill (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Tyler Hale Churchill (Madison, Wisconsin)
ABSTRACT A hearing assistance device and method is presented. An electrode is configured to be disposed within a cochlea of a user. A processor is in communication with the electrode and is configured to stimulate the electrode. The processor is configured to receive an input audio signal, band-pass filter the input audio signal into a plurality of channel signals, apply a Hilbert transform to at least one of the plurality of channel signals to generate a transformed audio signal, and analyze the transformed audio signal to identify at least one positive-moving zero crossing of the transformed audio signal. Upon identifying the at least one positive-moving zero crossing of the transformed audio signal, the processor is configured to trigger an electric current pulse to be delivered to the electrode.
FILED Tuesday, February 21, 2012
APPL NO 13/400754
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/57
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694263 Wigler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Michael H Wigler (Cold Spring Harbor, New York);  John Healy (East Northport, New York);  Robert Lucito (East Meadow, New York)
ASSIGNEE(S) Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
INVENTOR(S) Michael H Wigler (Cold Spring Harbor, New York);  John Healy (East Northport, New York);  Robert Lucito (East Meadow, New York)
ABSTRACT The invention provides oligonucleotide probes that can be used to hybridize to a representation of nucleic acid sequences. Compositions containing the probes such as microarrays are also provided. The invention also provides methods of using these probes and compositions in therapeutic, diagnostic, and research applications. Systems and methods for using a word counting algorithm that can quickly and accurately count the number of times a particular string of characters (i.e., nucleotides) appears in a nucleotide sequence (e.g., a genome) are provided. This algorithm can be used to identify the oligonucleotide probes of the invention. The algorithm uses a transform of a genome and an auxiliary data structure to count the number of times a particular word occurs in the genome.
FILED Friday, May 21, 2004
APPL NO 10/851779
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694265 Porwancher
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Richard Porwancher (Princeton, New Jersey)
ASSIGNEE(S) Richard Porwancher (Princeton, New Jersey)
INVENTOR(S) Richard Porwancher (Princeton, New Jersey)
ABSTRACT A kit and test panel utilizing a multivariate diagnostic method based on optimizing diagnostic likelihood ratios through the effective use of multiple diagnostic tests is disclosed. The Neyman-Pearson Lemma provides a mathematical basis to produce optimal diagnostic results. The method can comprise identifying those tests optimal for inclusion in a diagnostic panel, weighting the result of each component test based on a multivariate algorithm described below, adjusting the algorithm's performance to satisfy predetermined specificity criteria, generating a likelihood ratio for a given patient's test results through said algorithm, providing a clinical algorithm that estimates the pretest probability of disease based on individual clinical signs and symptoms, combining the likelihood ratio and pretest probability of disease through Bayes' Theorem to generate a posttest probability of disease, interpreting that result as either positive or negative for disease based on a cutoff value, and treating a patient for disease if the posttest probability exceeds the cutoff value.
FILED Friday, July 15, 2011
APPL NO 13/184017
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694266 Mycek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Mary-Ann Mycek (Ann Arbor, Michigan);  Malavika Chandra (Lansdale, Pennsylvania);  James Scheiman (Sup Twp, Michigan);  Robert H. Wilson (Ann Arbor, Michigan);  Diane Simeone (Ann Arbor, Michigan);  Barbara McKenna (Ann Arbor, Michigan);  Jeremy Taylor (Ann Arbor, Michigan);  Oliver Lee (Ann Arbor, Michigan);  Leng-Chun Chen (Ann Arbor, Michigan);  William Lloyd (Wixom, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Mary-Ann Mycek (Ann Arbor, Michigan);  Malavika Chandra (Lansdale, Pennsylvania);  James Scheiman (Sup Twp, Michigan);  Robert H. Wilson (Ann Arbor, Michigan);  Diane Simeone (Ann Arbor, Michigan);  Barbara McKenna (Ann Arbor, Michigan);  Jeremy Taylor (Ann Arbor, Michigan);  Oliver Lee (Ann Arbor, Michigan);  Leng-Chun Chen (Ann Arbor, Michigan);  William Lloyd (Wixom, Michigan)
ABSTRACT Multimodal optical spectroscopy systems and methods produce a spectroscopic event to obtain spectroscopic response data from biological tissue, either ex vivo or in vivo, and compare the response data with a model configured to correlate the measured response data and the most probable attributes of the tissue, thus facilitating classification of the tissue based on those attributes.
FILED Wednesday, May 16, 2012
APPL NO 13/473471
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/27
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694355 Bui et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Hung Bui (Mountain View, California);  Steven Eker (East Palo Alto, California);  Daniel Elenius (San Mateo, California);  Melinda Gervasio (Mountain View, California);  Thomas J. Lee (San Francisco, California);  Mei Marker (Santa Clara, California);  David Morley (Camberwell, Australia);  Janet Murdock (Mountain View, California);  Karen Myers (Menlo Park, California);  Bart Peintner (Palo Alto, California);  Shahin Saadati (Santa Clara, California);  Eric Yeh (Alameda, California);  Neil Yorke-Smith (Mountain View, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Hung Bui (Mountain View, California);  Steven Eker (East Palo Alto, California);  Daniel Elenius (San Mateo, California);  Melinda Gervasio (Mountain View, California);  Thomas J. Lee (San Francisco, California);  Mei Marker (Santa Clara, California);  David Morley (Camberwell, Australia);  Janet Murdock (Mountain View, California);  Karen Myers (Menlo Park, California);  Bart Peintner (Palo Alto, California);  Shahin Saadati (Santa Clara, California);  Eric Yeh (Alameda, California);  Neil Yorke-Smith (Mountain View, California)
ABSTRACT The present invention relates to a method and apparatus for assisting with automated task management. In one embodiment, an apparatus for assisting a user in the execution of a task, where the task includes one or more workflows required to accomplish a goal defined by the user, includes a task learner for creating new workflows from user demonstrations, a workflow tracker for identifying and tracking the progress of a current workflow executing on a machine used by the user, a task assistance processor coupled to the workflow tracker, for generating a suggestion based on the progress of the current workflow, and a task executor coupled to the task assistance processor, for manipulating an application on the machine used by the user to carry out the suggestion.
FILED Monday, June 01, 2009
APPL NO 12/476020
ART UNIT 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/7.270
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 08689414 Cavallaro
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Paul V. Cavallaro (Raynham, Massachusetts)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Paul V. Cavallaro (Raynham, Massachusetts)
ABSTRACT Crimp-imbalanced protective fabric is accomplished by varying the levels of yarn crimp within and across a layer or layers of a multi-layer fabric armor system. The method includes developing a crimp in the yarn (utilized for producing a fiber layer) by pulling the yarn through a solution that substantially coats the yarn. The removable coating has a thickness that ensures a proper amount of crimp in the yarn. The tension in the yarn is controlled; the yarn is weaved; and a crimp is applied in the yarn. Once the crimp is applied, families of the crimped yarn are utilized as a layer or layered to produce a soft armor form.
FILED Tuesday, July 30, 2013
APPL NO 13/954274
ART UNIT 3765 — SELECT * FROM codes_techcenter;
CURRENT CPC
Textiles: Manufacturing
028/168
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08689601 Allam
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Mahdy A. Allam (Glastonbury, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Mahdy A. Allam (Glastonbury, Connecticut)
ABSTRACT An assembly includes a debris monitor mount, a motor, and a particle belt. The particle belt carries one or more metallic particles. The particle belt is driven by the motor. The particle belt extends proximate the debris monitor mount when driven by the motor.
FILED Thursday, June 30, 2011
APPL NO 13/173118
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/1.30
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08689631 Tally et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Charles Tally (San Diego, California);  Richard L. Waters (San Diego, California)
ASSIGNEE(S) The United States of America as represented by Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Charles Tally (San Diego, California);  Richard L. Waters (San Diego, California)
ABSTRACT A gyroscope comprising: a multi-layer substrate, comprising drive spring and sense spring layers; a rigid support structure formed from the substrate; a plurality of drive springs formed in each drive spring layer wherein each drive spring is operatively coupled to the support structure; a drive mass formed from at least one layer of the substrate, wherein the drive mass is coupled to the support structure via the drive springs; a drive mass driver operatively coupled to the drive mass and configured to cause movement of the drive mass with respect to the support structure; a plurality of sense springs formed in each sense spring layer, wherein each sense spring is operatively coupled to the drive mass; and a sense mass formed from at least one layer, wherein the sense mass is coupled to the drive mass via the sense springs.
FILED Thursday, June 23, 2011
APPL NO 13/167539
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/504.120
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08689648 Heff
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Allan Heff (Newton, Massachusetts)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Allan Heff (Newton, Massachusetts)
ABSTRACT Provided is an aerosol collector of reduced size having an aerosol inlet, an impactor plate containing several particle size-selecting nozzles therethrough, a replaceable collection layer and a fan having a power supply such as a battery pack, all of which fits a small container, attachable to, e.g., the lapel of the user, means to rotate the fan and move the aerosol through the sampler, so as to draw airborne particles through the inlet and through one or more nozzles, to impact the particles on the layer for analysis of same.
FILED Friday, February 06, 2009
APPL NO 12/322961
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/863.220
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08689668 Rider et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Aaron Rider (Susquehanna, Pennsylvania);  Taylor Hale (Sparta, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Aaron Rider (Susquehanna, Pennsylvania);  Taylor Hale (Sparta, New Jersey)
ABSTRACT An automatic crimping tool may be used to seat and crimp a projectile in a cartridge case. The tool may include a center sleeve having a blind bore at one end, an outer surface, a spring stop disposed on the outer surface, and at least one opening extending through a wall of the blind bore. The tool may include an outer sleeve having a through bore. The center sleeve may be reciprocably disposed in the through bore of the outer sleeve. The through bore may include a counter bore at one end and an enlarged portion located distal from the counter bore. A spring may be disposed between a flat portion of the counter bore and the spring stop. A retainer may bear against the spring stop to limit axial motion of the center sleeve. An inner sleeve may be disposed in the blind bore. The inner sleeve may be selectively translatable with the center sleeve. A second spring may be disposed between a closed end of the blind bore and the inner sleeve.
FILED Tuesday, December 20, 2011
APPL NO 13/331468
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosive-charge making
086/43
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US 08689714 Ramotowski
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Thomas S. Ramotowski (Tiverton, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Thomas S. Ramotowski (Tiverton, Rhode Island)
ABSTRACT An electrochemical engine for buoyancy is provided with the engine having a water-tight and gas-tight chamber containing a volume of seawater. The electrochemical buoyancy engine contributes electrons for reduction of hydrogen protons in the seawater using a sufficient voltage applied to an anode and a cathode disposed in the seawater. The generated hydrogen gas is held in the chamber to provide the desired buoyancy and can be vented to adjust the buoyancy.
FILED Thursday, August 26, 2010
APPL NO 12/868876
ART UNIT 3617 — Fluid Handling and Dispensing
CURRENT CPC
Ships
114/125
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US 08689726 Krogman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Kevin C. Krogman (Cambridge, Massachusetts);  Paula T. Hammond (Newton, Massachusetts);  Nicole S. Zacharia (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute Of Technology (Cambridge, Massachusetts)
INVENTOR(S) Kevin C. Krogman (Cambridge, Massachusetts);  Paula T. Hammond (Newton, Massachusetts);  Nicole S. Zacharia (Cambridge, Massachusetts)
ABSTRACT The present invention comprises an automated apparatus capable of spray depositing polyelectrolytes via the LbL mechanism with minimal or no human interaction. In certain embodiments, the apparatus sprays atomized polyelectrolytes onto a vertically oriented substrate. To counteract the effects of irregular spray patterns, the substrate is preferably slowly rotated about a central axis. In certain embodiments, the apparatus also includes a forced pathway for the droplets, such as a pathway created by using a vacuum. In this way, a thicker or three-dimensional substrate can be coated. In certain embodiments, the apparatus is designed so as to be scalable. Thus, through the use of multiple instantiations of the apparatus, a large or irregularly shaped substrate can be coated. Rolls of textile can therefore be coated using the apparatus. Additionally, the present invention includes a method to uniformly coat a substrate, such as a hydrophobic textile material, using aqueous solutions of polyelectrolytes.
FILED Friday, July 06, 2012
APPL NO 13/543105
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating apparatus
118/313
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US 08690331 Culjat et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Martin Culjat (Los Angeles, California);  Priyamvada Tewari (Los Angeles, California);  Jean L. Bourges (Paris, France);  Jean P. Hubschman (Los Angeles, California);  Rahul S. Singh (Palo Alto, California);  Zachary Taylor (Poway, California);  Warren S. Grundfest (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Martin Culjat (Los Angeles, California);  Priyamvada Tewari (Los Angeles, California);  Jean L. Bourges (Paris, France);  Jean P. Hubschman (Los Angeles, California);  Rahul S. Singh (Palo Alto, California);  Zachary Taylor (Poway, California);  Warren S. Grundfest (Los Angeles, California)
ABSTRACT A corneal hydration sensing system includes an illumination system configured to provide an illumination beam of terahertz radiation, an optical system arranged in an optical path of the illumination system to relay and direct at least a portion of the illumination beam of terahertz radiation onto a cornea of a subject and to receive at least a portion of terahertz radiation reflected from the cornea to provide a return beam of terahertz radiation, and a detection system arranged in an optical path of the return beam of terahertz radiation. The detection system is configured to provide a detection signal from detecting at least a portion of the return beam of terahertz radiation. The corneal hydration sensing system also includes a signal processing system configured to communicate with the detection system to receive the detection signal. The signal processing system processes the detection signal to provide a measure of an amount of hydration sensed in the cornea of the subject.
FILED Wednesday, August 29, 2012
APPL NO 13/597947
ART UNIT 2872 — Optics
CURRENT CPC
Optics: Eye examining, vision testing and correcting
351/221
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US 08690527 Matwey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Mark Matwey (Phoenix, Arizona);  David K. Jan (Fountain Hills, Arizona)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Mark Matwey (Phoenix, Arizona);  David K. Jan (Fountain Hills, Arizona)
ABSTRACT A flow discouraging system includes a stator assembly, a rotor assembly, and a plurality of fingers. The stator assembly includes one or more stationary components forming a side wall, the side wall including an annular groove defined by an outer axially-extending surface, an inner axially-extending surface, and a radial surface extending between the outer and inner axially-extending surfaces. The rotor assembly is disposed adjacent to and spaced apart from the stator assembly to form a portion of a cavity and includes an annular rim extending at least partially into the annular groove. The plurality of fingers is disposed in the annular groove and extends from the one or more stationary components the annular rim.
FILED Wednesday, June 30, 2010
APPL NO 12/827296
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/173.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08690617 Langenfeld et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) Christopher C. Langenfeld (Nashua, New Hampshire);  Christopher M. Werner (San Jose, California);  Ryan K. LaRocque (Pepperell, Massachusetts);  Thomas S. Schnellinger (North Andover, Massachusetts);  Stanley B. Smith, III (Raymond, New Hampshire)
ASSIGNEE(S) DEKA Products Limited Partnership (Manchester, New Hampshire)
INVENTOR(S) Christopher C. Langenfeld (Nashua, New Hampshire);  Christopher M. Werner (San Jose, California);  Ryan K. LaRocque (Pepperell, Massachusetts);  Thomas S. Schnellinger (North Andover, Massachusetts);  Stanley B. Smith, III (Raymond, New Hampshire)
ABSTRACT A swimming propulsion device. The swimming propulsion device includes a fuselage at least one propulsor pivotally connected to the fuselage, and in some embodiments, at least one stabilizer affixed to the fuselage. The device also includes a swimmer connection mechanism removably attached to the fuselage by a locking mechanism whereby the swimmer connection mechanism connects a swimmer to the device, and a control mechanism installed within the propulsor. A method for efficient swimming is also disclosed.
FILED Monday, March 28, 2011
APPL NO 13/073343
ART UNIT 3617 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Marine propulsion
440/21
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US 08690865 Prausnitz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Mark R. Prausnitz (Atlanta, Georgia);  Mark G. Allen (Atlanta, Georgia);  Jung-Hwan Park (Smyrna, Georgia);  Yong-Kyu Yoon (Smyrna, Georgia);  Jin-Woo Park (Suwanee, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Mark R. Prausnitz (Atlanta, Georgia);  Mark G. Allen (Atlanta, Georgia);  Jung-Hwan Park (Smyrna, Georgia);  Yong-Kyu Yoon (Smyrna, Georgia);  Jin-Woo Park (Suwanee, Georgia)
ABSTRACT The present invention comprises methods and devices for thermal treatment of a barrier to increase the permeability of the barrier. One form of increasing the permeability of the barrier comprises forming micropores which may be used for administration of active agents across the barrier, or may be used for sampling or collecting fluids, or may be used for detecting, measuring or determining analytes, or may be used for monitoring of physiological or other conditions. Devices of the present invention may comprise microheaters that are activated by inductive or ohmic heating power supply components.
FILED Tuesday, May 31, 2005
APPL NO 11/597969
ART UNIT 3739 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
66/28
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US 08691010 Hansen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Carl L. Hansen (Pasadena, California);  Morten Sommer (Copenhagen NV, Denmark);  Stephen R. Quake (San Marino, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Carl L. Hansen (Pasadena, California);  Morten Sommer (Copenhagen NV, Denmark);  Stephen R. Quake (San Marino, California)
ABSTRACT The use of microfluidic structures enables high throughput screening of protein crystallization. In one embodiment, an integrated combinatoric mixing chip allows for precise metering of reagents to rapidly create a large number of potential crystallization conditions, with possible crystal formations observed on chip. In an alternative embodiment, the microfluidic structures may be utilized to explore phase space conditions of a particular protein crystallizing agent combination, thereby identifying promising conditions and allowing for subsequent focused attempts to obtain crystal growth.
FILED Friday, April 15, 2011
APPL NO 13/087697
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/68
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US 08691011 Samuelson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Lars Samuelson (Malmö, Sweden);  Thomas Mårtensson (Lund, Sweden);  Werner Seifert (Sebnitz, Germany);  Anders Mikkelsen (Arlöv, Sweden);  Bernhard Mandl (Pfarrkirchen, Austria)
ASSIGNEE(S) QuNano AB (Lund, Sweden)
INVENTOR(S) Lars Samuelson (Malmö, Sweden);  Thomas Mårtensson (Lund, Sweden);  Werner Seifert (Sebnitz, Germany);  Anders Mikkelsen (Arlöv, Sweden);  Bernhard Mandl (Pfarrkirchen, Austria)
ABSTRACT The present invention relates to epitaxial growth of nanowires on a substrate. In particular the invention relates to growth of nanowires on an Si-substrate without using Au as a catalyst. In the method according to the invention an oxide template is provided on a passivated surface of the substrate. The oxide template defines a plurality of nucleation onset positions for subsequent nanowire growth. According to one embodiment a thin organic film is used to form the oxide template.
FILED Wednesday, March 07, 2007
APPL NO 12/224822
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/88
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US 08691104 Greer et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Harold F. Greer (Pasadena, California);  Julia R. Greer (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Harold F. Greer (Pasadena, California);  Julia R. Greer (Pasadena, California)
ABSTRACT A method of controlling wetting characteristics is described. Such method includes forming and configuring nanostructures on a surface where controlling of the wetting characteristics is desired. Surfaces and methods of fabricating such surfaces are also described.
FILED Friday, January 13, 2012
APPL NO 13/350734
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Etching a substrate: Processes
216/59
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US 08691116 Han et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Moon Gyu Han (Yongin-si, South Korea);  Jay K. Sperry (Pendleton, South Carolina);  Samuel T. Ingram (Seneca, South Carolina);  Stephen H. Foulger (Clemson, South Carolina)
ASSIGNEE(S) Clemson University (Clemson, South Carolina)
INVENTOR(S) Moon Gyu Han (Yongin-si, South Korea);  Jay K. Sperry (Pendleton, South Carolina);  Samuel T. Ingram (Seneca, South Carolina);  Stephen H. Foulger (Clemson, South Carolina)
ABSTRACT Disclosed are conductive polymer inks and methods for forming the inks. The disclosed inks include a dispersion of conductive core/shell nanoparticles. The core/shell nanoparticles include a polymeric core and a shell formed of a conducting polymer. The inks can include a dispersion of the core/shell nanoparticles in a liquid carrier, such as an alcohol. The disclosed inks can be formulated to high viscosities and can be utilized in high-speed printing processes including rotogravure and flexographic printing processes. Products encompassed by the disclosure include polymer devices such as sensors, OFETs, RFID tags, printed circuit board, electrochromic devices, non-volatile memory devices, photovoltaics, and the like.
FILED Friday, March 23, 2007
APPL NO 12/293826
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions
252/500
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US 08691178 Forrest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Communications-Electronics Command (CECOM)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Stephen R. Forrest (Ann Arbor, Michigan);  Jeramy D. Zimmerman (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Jeramy D. Zimmerman (Ann Arbor, Michigan)
ABSTRACT A method of processing bundles of carbon nanotubes (CNTs). Bundles of CNTs are put into a solution and unbundled using sonication and one or more surfactants that break apart and disperse at least some of the bundles into the solution such that it contains individual semiconducting CNTs, individual metallic CNTs, and remaining CNT bundles. The individual CNTs are separated from each other using agarose bead column separation using sodium dodecyl sulfate as a surfactant. Remaining CNT bundles are then separated out by performing density-gradient ultracentrifugation.
FILED Friday, June 03, 2011
APPL NO 13/153382
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/447.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691371 Kim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Tae Won Kim (San Jose, California);  Min Yan (Ballston Lake, New York);  Ahmet Gun Erlat (Clifton Park, New York);  Thomas Bert Gorczyca (Schenectady, New York);  Christian Maria Anton Heller (Albany, New York);  Paul Alan McConnelee (Schenectady, New York);  Marc Schaepkens (Medina, Ohio)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Tae Won Kim (San Jose, California);  Min Yan (Ballston Lake, New York);  Ahmet Gun Erlat (Clifton Park, New York);  Thomas Bert Gorczyca (Schenectady, New York);  Christian Maria Anton Heller (Albany, New York);  Paul Alan McConnelee (Schenectady, New York);  Marc Schaepkens (Medina, Ohio)
ABSTRACT A barrier coating for a composite article is provided. The barrier coating includes an organic zone; an inorganic zone; and an interface zone between the organic zone and the inorganic zone.
FILED Thursday, July 26, 2007
APPL NO 11/828543
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/216
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US 08691582 Halden
FUNDED BY
Department of Defense (DOD)
Environmental Security Technology Certification Program (ESTCP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Rolf U. Halden (Phoenix, Arizona)
ASSIGNEE(S) Arizona Board of Regents (Scottsdale, Arizona)
INVENTOR(S) Rolf U. Halden (Phoenix, Arizona)
ABSTRACT A method for in situ monitoring within a specified environment. The method includes locating a housing in a well, wherein a set of pumps and a plurality of test beds are inserted. Each of the set of pumps are controlled by signals from the control system to push water from each pump into one of the plurality of separate test beds where, after flowing through each of the test beds, effluent flows into an effluent storage device.
FILED Monday, November 19, 2012
APPL NO 13/681125
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/28
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US 08691586 Bayley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) John Hagen Pryce Bayley (Oxford, United Kingdom);  Matthew Holden (Oxford, United Kingdom);  Andrew John Heron (Oxford, United Kingdom);  David Needham (Durham, North Carolina)
ASSIGNEE(S) ISIS Innovation Limited (Oxford, United Kingdom)
INVENTOR(S) John Hagen Pryce Bayley (Oxford, United Kingdom);  Matthew Holden (Oxford, United Kingdom);  Andrew John Heron (Oxford, United Kingdom);  David Needham (Durham, North Carolina)
ABSTRACT A method of forming bilayers of amphipathic molecules uses droplets of aqueous solution in a hydrophobic medium such as oil. A layer of amphipathic molecules such as a lipid is formed around the surfaces of the droplets. This may be achieved by providing the lipid in the oil and leaving the droplets for a time sufficient to form the layer. The droplets are brought into contact with one another so that a bilayer of the amphipathic molecules is formed as an interface between the contacting droplets. The bilayers may be used for a wide range of studies. The technique has numerous advantages including providing a long lifetime for the bilayers, allowing study of small volumes and allowing the construction of chains and networks of droplets with bilayers in between to study complex systems.
FILED Friday, September 07, 2012
APPL NO 13/607337
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/71
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US 08691591 Walt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Trustees of Tufts College, Tufts University (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) David R. Walt (Lexington, Massachusetts);  Todd A. Dickinson (San Diego, California)
ABSTRACT Disclosed herein are compositions and methods for combining the output obtained from redundant sensor elements in a sensor array.
FILED Monday, March 25, 2013
APPL NO 13/850154
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Analytical and immunological testing
436/164
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US 08691729 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) David R. Liu (Lexington, Massachusetts);  Matthew William Kanan (Palo Alto, California);  Mary M. Rozenman (New York, New York)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Lexington, Massachusetts);  Matthew William Kanan (Palo Alto, California);  Mary M. Rozenman (New York, New York)
ABSTRACT A novel reaction discovery system that does not depend on DNA duplex formation is provided. The advantages of this system include exploring reactions conditions not possible where DNA hybridization is required. For example, the inventive reaction discovery system allows for reaction conditions using organic solvents, higher temperatures, and water-insoluble reagents, catalysts, and ligands. The invention also provides single-stranded oligonucleotide templates with substrate pairs covalently attached and methods of screening for reaction conditions that result in a direct covalent bond between the substrates. Kits are also provided for practicing this novel reaction discovery system.
FILED Wednesday, January 09, 2008
APPL NO 11/971642
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Combinatorial chemistry technology: Method, library, apparatus
56/11
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US 08691768 Fields et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Howard L. Fields (Berkeley, California);  Jennifer M. Mitchell (Berkeley, California);  Elyssa B. Margolis (Berkeley, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Howard L. Fields (Berkeley, California);  Jennifer M. Mitchell (Berkeley, California);  Elyssa B. Margolis (Berkeley, California)
ABSTRACT The present invention provides methods of treating or preventing a substance-related disorder using selective delta opioid receptor-1 (DOP-R1) agonists, delta opioid receptor-2 (DOP-R2) antagonists, and/or mu opioid receptor (MOP-R) antagonists, or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof. The methods provided herein further comprise administering a therapeutically effective amount of a combination of a DOP-R1 agonist and a DOP-R2 antagonist. The methods also comprise administering a therapeutically effective amount of a combination of a DOP-R1 agonist and an MOP-R antagonist. The methods provided herein further comprise administering a therapeutically effective amount of a combination of a DOP-R1 agonist and a DOP-R2 antagonist and a MOP-R antagonist. The invention also relates to compositions containing the same. The invention also relates to methods of determining delta opioid receptor specificity of candidate agents.
FILED Friday, May 01, 2009
APPL NO 12/990487
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/17.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691859 Bavari et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
APPLICANT(S) Sina Bavari (Frederick, Maryland);  Rekha G. Panchal (Frederick, Maryland);  Rick Gussio (Frederick, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Sina Bavari (Frederick, Maryland);  Rekha G. Panchal (Frederick, Maryland);  Rick Gussio (Frederick, Maryland)
ABSTRACT Disclosed herein are methods of inhibiting, reducing or preventing growth of or destroying bacteria of at least one bacterial strain which comprises contacting the bacteria with the compounds disclosed herein. Also disclosed are methods of treating, inhibiting or preventing an infection or intoxication caused by bacteria of at least one bacterial strain in a subject and pharmaceutical and cosmetic compositions comprising the compounds disclosed herein.
FILED Friday, August 11, 2006
APPL NO 11/464001
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/394
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692171 Miller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Gerald F Miller (Bedford, Indiana);  James Stewart (Bloomington, Indiana)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gerald F Miller (Bedford, Indiana);  James Stewart (Bloomington, Indiana)
ABSTRACT An unmanned aerial vehicle including a controller operating in a search mode of operation where a receiver of an acquisition sensor searches for a target and causes flight control surfaces to guide the vehicle in a downward spiral path, a terminal mode of operation where the acquisition sensor detects a target and causes flight control surfaces to direct the vehicle toward the target, and an activation mode of operation where a trigger sensor detects a target within a predetermined distance to the vehicle and the controller activates a responder.
FILED Thursday, September 20, 2012
APPL NO 13/623551
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/3.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692176 Kelly et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Michael Kelly (North Reading, Massachusetts);  Brian Tyrrell (Brookline, New Hampshire);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Kenneth Schultz (Lexington, Massachusetts);  James Wey (Arlington, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Michael Kelly (North Reading, Massachusetts);  Brian Tyrrell (Brookline, New Hampshire);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Kenneth Schultz (Lexington, Massachusetts);  James Wey (Arlington, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ABSTRACT A digital focal plane array includes an all-digital readout integrated circuit in combination with a detector array. The readout circuit includes unit cell electronics, orthogonal transfer structures, and data handling structures. The unit cell electronics include an analog to digital converter. Orthogonal transfer structures enable the orthogonal transfer of data among the unit cells. Data handling structures may be configured to operate the digital focal plane array as a data encryptor/decipherer. Data encrypted and deciphered by the digital focal plane array need not be image data.
FILED Friday, November 18, 2011
APPL NO 13/299995
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/208.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692293 Khan et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) M. Asif Khan (Irmo, South Carolina);  Vinod Adivarahan (Columbia, South Carolina);  Qhalid Fareed (Richardson, Texas);  Grigory Simin (Columbia, South Carolina);  Naveen Tipimeni (Plano, Texas)
ABSTRACT Methods of achieving high breakdown voltages in semiconductor devices by suppressing the surface flashover using high dielectric strength insulating encapsulation material are generally described. In one embodiment of the present invention, surface flashover in AlGaN/GaN heterostructure field-effect transistors (HFETs) is suppressed by using high dielectric strength insulating encapsulation material. Surface flashover in as-fabricated III-Nitride based HFETs limits the operating voltages at levels well below the breakdown voltages of GaN.
FILED Monday, November 05, 2012
APPL NO 13/668564
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/194
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692396 Lai et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) William W. Lai (Ridgecrest, California);  Alfred J. Baca (Ridgecrest, California);  M. Joseph Roberts (Ridgecrest, California);  Lawrence C. Baldwin (Ridgecrest, California);  Michael T. Owens (Ridgecrest, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) William W. Lai (Ridgecrest, California);  Alfred J. Baca (Ridgecrest, California);  M. Joseph Roberts (Ridgecrest, California);  Lawrence C. Baldwin (Ridgecrest, California);  Michael T. Owens (Ridgecrest, California)
ABSTRACT A hybrid system for harvesting magnetic and electrical energy includes a substrate, at least one permanent magnet, and at least one coil of wire equal in number to the permanent magnet. Each permanent magnet is configured to fit in the substrate. Each coil of wire is configured to fit circumferentially around a respective permanent magnet. Each coil of wire is configured to fit in the substrate.
FILED Wednesday, June 13, 2012
APPL NO 13/495278
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Prime-mover dynamo plants
290/1.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692397 Lai et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Secretary of the Navy (China Lake, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) William W. Lai (Ridgecrest, California);  Alfred J. Baca (Ridgecrest, California);  M. Joseph Roberts (Ridgecrest, California);  Lawrence C. Baldwin (Ridgecrest, California);  Michael T. Owens (Escondido, California)
ABSTRACT A mechanism for the conversion of vertical motion to translational or rotational motion includes a substrate, at least one permanent magnet, at least one coil of wire, at least one inelastic material, at least one elastic material, and at least one pivot point. The coil of wire is a solenoid.
FILED Wednesday, December 26, 2012
APPL NO 13/727254
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Prime-mover dynamo plants
290/1.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692575 Gershenfeld et al.
FUNDED BY
Department of Defense (DOD)
Defense MicroElectronics Activity (DMEA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Neil Gershenfeld (Somerville, Massachusetts);  Kailiang Chen (Cambridge, Massachusetts);  David Allen Dalrymple (Columbia, Maryland)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Neil Gershenfeld (Somerville, Massachusetts);  Kailiang Chen (Cambridge, Massachusetts);  David Allen Dalrymple (Columbia, Maryland)
ABSTRACT A family of self-timed, charge-conserving asynchronous logic elements that interact with their nearest neighbors permits design and implementation of circuits that are asynchronous at the bit level. The elements pass information by means of state tokens, rather than voltages. Each cell is self-timed, so no hardware non-local connections are needed. An asynchronous logic element comprises a set of edges for asynchronous communication with at least one neighboring cell, the edges receiving state tokens from neighboring logic elements and transferring output state tokens to neighboring logic elements, and circuitry configured to perform, when the circuitry inputs contain valid tokens and the circuitry outputs are empty, a logic operation utilizing received tokens as inputs, thereby producing an output token reflecting the result of the logic operation.
FILED Tuesday, October 11, 2011
APPL NO 13/271179
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electronic digital logic circuitry
326/38
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692691 Fung et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Yau L. Fung (Fairfax, Virginia);  Andrew J. Hill (Springfield, Virginia);  Paul W. Bachelder (Fairfax, Virginia);  Robert B. Mayer (Alexandria, Virginia);  Blaine C. Froeschl (Clifton, Virginia);  Alden K. Lum (Vienna, Virginia);  Miguel P. Snyder (Fairfax, Virginia);  Kim W. D. Larsen (Alexandria, Virginia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Yau L. Fung (Fairfax, Virginia);  Andrew J. Hill (Springfield, Virginia);  Paul W. Bachelder (Fairfax, Virginia);  Robert B. Mayer (Alexandria, Virginia);  Blaine C. Froeschl (Clifton, Virginia);  Alden K. Lum (Vienna, Virginia);  Miguel P. Snyder (Fairfax, Virginia);  Kim W. D. Larsen (Alexandria, Virginia)
ABSTRACT An infrared laser landing marker system provides a capability to mark a boundary line of varying lengths with near infrared lasers, e.g., of the order 8xx nm. This system can be either directly operated or remotely operated via satellite communications and is compatible with currently fielded night vision goggles. Two modules, placed at either end of boundary, self align to each other and then proceed to mark a boundary edge of a landing zone with an infrared laser line.
FILED Thursday, May 10, 2012
APPL NO 13/468248
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Communications: Electrical
340/947
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692717 Friedman
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Robert Friedman (Las Vegas, Nevada)
ASSIGNEE(S) Noninvasive Medical Technologies, Inc. (Las Vegas, Nevada)
INVENTOR(S) Robert Friedman (Las Vegas, Nevada)
ABSTRACT An antenna includes an antenna layer, a ground layer and a dielectric layer between the antenna layer and the ground layer. The antenna layer and the ground layer form a figure in the shape of two identical mirror image triangles joined together at a longest side of each one of the triangles where each side of each triangle is a different length.
FILED Monday, March 23, 2009
APPL NO 12/383356
ART UNIT 3737 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Communications: Radio wave antennas
343/700.MS0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692729 Ball et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Thomas A. Ball (Bloomington, Indiana);  Jeffrey M. Snow (Bloomington, Indiana)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Thomas A. Ball (Bloomington, Indiana);  Jeffrey M. Snow (Bloomington, Indiana)
ABSTRACT An apparatus, method of propagating a signal and method of manufacture for an antenna structure comprising a section which is positioned or formed in relation to a portion of the antenna structure, such that a portion of the electromagnetic (EM) field that is emitted from the antenna structure is partially slowed or phase shifted thereby resulting in an improvement of the horizontal gain of the EM field.
FILED Friday, March 25, 2011
APPL NO 13/072403
ART UNIT 2876 — Optics
CURRENT CPC
Communications: Radio wave antennas
343/753
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693183 Alameda et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Patti Alameda (Budd Lake, New Jersey);  David J. Rychalsky (East Brunswick, New Jersey);  James Ireland (Lake Hopatcong, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Patti Alameda (Budd Lake, New Jersey);  David J. Rychalsky (East Brunswick, New Jersey);  James Ireland (Lake Hopatcong, New Jersey)
ABSTRACT An adapter for a ruggedized personal digital assistant (RPDA) may include a generally L-shaped housing with first and second legs. The first leg may have a generally tubular shape and may include a protruding ridge that is slidable in a stylus groove of the RPDA. The first leg may include a connector for a multi-function cable and an opening for a communication cable. The second leg may include a power connector for engaging the power-in port of the RPDA and a serial data connector for engaging the serial data port of the RPDA. A multi-function cable assembly may be disposed in the first leg and may connect to the multi-function cable connector. Inside the first leg, the multi-function cable assembly may split into a plurality of cables for connecting to the RPDA.
FILED Wednesday, November 17, 2010
APPL NO 12/947993
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/679.410
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693288 O'Brien, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Francis J. O'Brien, Jr. (Newport, Rhode Island);  Aimee M. Ross (New Bedford, Massachusetts)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Francis J. O'Brien, Jr. (Newport, Rhode Island);  Aimee M. Ross (New Bedford, Massachusetts)
ABSTRACT A method is provided for characterizing data sets containing data points. The method can characterize the data sets as random or as non-random. In the method, a convex hull envelope is constructed which contains the data points and passes through at least four non-coplanar data points. The convex hull envelope is partitioned into cells. The method classifies the data set as a sized sample. Based on the classification, a predetermined set of tests is selected for operating on the data set.
FILED Tuesday, October 04, 2011
APPL NO 13/317035
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/135
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693345 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Seoung Bum Lee (Lexington, Massachusetts);  Gowri Shankar Rajappan (Somerville, Massachusetts)
ASSIGNEE(S) Mayflower Communications Company, Inc. (Burlington, Massachusetts)
INVENTOR(S) Seoung Bum Lee (Lexington, Massachusetts);  Gowri Shankar Rajappan (Somerville, Massachusetts)
ABSTRACT System and method for topology management of dynamic ad hoc wireless communication networks. The network nodes are organized in a multi-level hierarchical architecture whereby the nodes at each level are managed by nodes at the next higher level. In a three-layer network, leaf nodes populate the lowest level, cluster head nodes the intermediate level, and regional head nodes the highest level. Priority-based backbone tree paths are constructed by selecting and connecting high capability nodes, such that the unselected nodes are one-hop away from a connected node. In a two backbone tree path construction, a primary backbone tree path carries the high priority traffic and a secondary backbone tree path carries the lower priority traffic. The connectivities of the backbone tree paths are maintained dynamically. So also are high priority traffic flows using the Dynamic Priority Threshold mechanism with High Fidelity Monitoring and traffic siphoning via unutilized network resources.
FILED Wednesday, October 12, 2011
APPL NO 13/317214
ART UNIT 2475 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Multiplex communications
370/241
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693365 Phillips et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Brian E. Phillips (Crownsville, Maryland);  Murali Tummala (Monterey, California);  John McEachen (Carmel, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brian E. Phillips (Crownsville, Maryland);  Murali Tummala (Monterey, California);  John McEachen (Carmel, California)
ABSTRACT Embodiments in accordance with the invention provide a state-based channel selection method to improve the rate of successful transmissions for a multi-channel wireless network. Channels are monitored for performance, and, based upon performance, are placed in channel state vectors having increasing levels of desirability. The higher the state vector in which a channel is placed, the more desirable the channel is considered for selection. The channel in the highest state vector is considered for selection first. A channel not in the highest desirable state vector is eligible for selection when a channel is unavailable from higher desirable state vectors. Channels not in the highest desirable state vector, but also not in the lowest undesirable state vector, are monitored for improvement to move into higher desirable state vectors as they improve.
FILED Monday, June 04, 2012
APPL NO 13/487494
ART UNIT 2478 — Multiplex and VoIP
CURRENT CPC
Wireless Communication Networks
H04W 28/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693452 Lauff et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Sarah M. Lauff (San Diego, California);  Ayax D. Ramirez (Chula Vista, California);  Russel E. Clement (El Cajon, California);  Joel T. Baumbaugh (San Diego, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Sarah M. Lauff (San Diego, California);  Ayax D. Ramirez (Chula Vista, California);  Russel E. Clement (El Cajon, California);  Joel T. Baumbaugh (San Diego, California)
ABSTRACT Physiological conditions of a plurality of individuals are monitored by using signals provided by sensors on each individual. Each individual has, positioned in close proximity to the individual, one or more sensors for sensing a physiological condition of the individual. A control module is capable of communicating with an external communication station and with the sensors. A wireless networked communication link is established between the control module and the external communication station. Indications of the physiological conditions for a plurality of individuals or physiological conditions derived from the physiological sensors, are transmitted on the wireless networked communication link to the external communication station.
FILED Wednesday, June 29, 2011
APPL NO 13/172497
ART UNIT 2471 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/338
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693509 Bowers et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) John E. Bowers (Santa Barbara, California);  Daoxin Dai (Hangzhou, China PRC)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) John E. Bowers (Santa Barbara, California);  Daoxin Dai (Hangzhou, China PRC)
ABSTRACT Loss modulated silicon evanescent lasers are disclosed. A loss-modulated semiconductor laser device in accordance with one or more embodiments of the present invention comprises a semiconductor-on-insulator (SOI) structure resident on a first substrate, the SOI structure comprising a waveguide in a semiconductor layer of the SOI structure, and a semiconductor structure bonded to the semiconductor layer of the SOI structure, wherein at least one region in the semiconductor layer of the SOI structure controls a photon lifetime in the semiconductor laser device.
FILED Wednesday, June 30, 2010
APPL NO 12/827776
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693631 Lee
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Susanne Madeline Lee (Cohoes, New York)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Susanne Madeline Lee (Cohoes, New York)
ABSTRACT A craser device, imaging system utilizing a craser device, and a method of imaging. The craser device includes a gain medium with excited gain medium atoms that emit x-ray and/or gamma-ray photons, a transmission medium abutting the gain medium, and a reflecting mirror comprising one or more lower refractive index layers and abutting the transmission medium. The transmission medium has a higher refractive index than the gain medium and at least one of the materials in the reflecting mirror. The x-ray and/or gamma-ray photons are confined to the transmission medium via total internal reflection and interact multiple times with the excited gain medium atoms through evanescent waves producing amplified stimulated emission leading to formation of a high intensity incoherent or coherent x-ray and/or gamma-ray beam.
FILED Monday, August 29, 2011
APPL NO 13/220466
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/82
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693720 Parkins
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) John W. Parkins (Ithaca, New York)
ASSIGNEE(S) Red Tail Hawk Corporation (Itaca, New York)
INVENTOR(S) John W. Parkins (Ithaca, New York)
ABSTRACT An improved wireless communications earplug for use with a magnetic field transmitter. The wireless earplug has a receiver made of a coil of wire on a magnetic bobbin, mounted in close proximity or in contact with a magnetic case of a speaker. The magnetic case of the speaker serves to increase the magnetic flux through the receiver and improves the efficiency of the earplug. The speaker is acoustically coupled to an eartip, and the earplug may be molded into a custom earplug body.
FILED Thursday, July 08, 2010
APPL NO 12/832363
ART UNIT 2654 — Audio Signals
CURRENT CPC
Electrical audio signal processing systems and devices
381/331
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693810 Suarez et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) John Suarez (Princeton, New Jersey);  Konstantin Kravtsov (Moscow, Russian Federation);  Paul R. Prucnal (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) John Suarez (Princeton, New Jersey);  Konstantin Kravtsov (Moscow, Russian Federation);  Paul R. Prucnal (Princeton, New Jersey)
ABSTRACT A system and method for cancellation of RF interference in the optical domain. The system and method utilize two Mach-Zehnder electrooptic modulators biased for parallel counter-phase modulation. The method of signal subtraction is referred to as incoherent optical subtraction, since two independent laser sources serve as the optical carrier waves. The system has produced the broadband cancellation result while simultaneously recovering a 50 dBm signal which was initially “buried” under the broadband interference. The cancellation depths achieved by the system are due to the accurate channel tracking and precise time delays attainable with modern optical devices—unattainable with state-of-the-art electronic devices at the time of this writing.
FILED Thursday, November 05, 2009
APPL NO 12/613512
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693837 Tischler et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Jonathan R. Tischler (Sharon, Massachusetts);  Michael Scott Bradley (Cambridge, Massachusetts);  Vladimir Bulovic (Lexington, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jonathan R. Tischler (Sharon, Massachusetts);  Michael Scott Bradley (Cambridge, Massachusetts);  Vladimir Bulovic (Lexington, Massachusetts)
ABSTRACT An optical fiber including a surface including a non-covalent multilayer including a light-absorbing material can be used to develop fluorescence microscopy with a lateral resolution of about 5 nm and possibly lower. The non-covalent multilayer can be a highly absorptive thin film, for example a film based on J-aggregates, which can be used with conventional Near-Field Scanning Optical Microscopy.
FILED Wednesday, March 19, 2008
APPL NO 12/531960
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/141
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693875 Banwell et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Thomas Banwell (Howell, New Jersey);  Anjali Agarwal (Matawan, New Jersey);  Paul Toliver (Tinton Falls, New Jersey);  Ted K. Woodward (Holmdel, New Jersey)
ASSIGNEE(S) Applied Communications Sciences (Basking Ridge, New Jersey)
INVENTOR(S) Thomas Banwell (Howell, New Jersey);  Anjali Agarwal (Matawan, New Jersey);  Paul Toliver (Tinton Falls, New Jersey);  Ted K. Woodward (Holmdel, New Jersey)
ABSTRACT A system and method for optimizing an optical RF photonic link system is presented. The system comprises a modulator subsystem in which nonlinear response is compensated by an envelope precompensation method and employs an optical filter to suppress optical carriers and extract modulated sidebands, an optical amplifier, and an array of photodetectors, each having a plurality of pairs of diodes. The modulator subsystem performs optical filtering on the signal, the signal is amplified by the optical amplifier and sent to the array of photodetectors. The optical amplifier can be an erbium doped fiber amplifier, or a phase sensitive amplifier. The optical power can be delivered to each diode of the array of photodetectors via a photonic integrated circuit.
FILED Thursday, November 19, 2009
APPL NO 12/621863
ART UNIT 2637 — Optical Communications
CURRENT CPC
Optical communications
398/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693893 Johnson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) David M. S. Johnson (Somerville, Massachusetts);  Jason M. Hogan (Palo Alto, California);  Sheng-wey Chiow (Palo Alto, California);  Mark A. Kasevich (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) David M. S. Johnson (Somerville, Massachusetts);  Jason M. Hogan (Palo Alto, California);  Sheng-wey Chiow (Palo Alto, California);  Mark A. Kasevich (Palo Alto, California)
ABSTRACT Optical phase modulators are disposed in separate arms of an optical interferometer for forming short optical pulses. The optical phase modulators are driven by signals from an electrical nonlinear transmission line (NLTL). A time delay (typically on the order of the NLTL fall time) is introduced between the NLTL signals in the two arms of the interferometer. With this arrangement, the interferometer provides short optical pulses at its output. In one experiment, 70 ps switching was demonstrated using discrete LiNbO3 traveling wave electro-optic modulators and commercially available NLTLs capable of delivering a 35 ps falling edge. A preferable approach is to integrate the NLTLs with the phase modulators, to further improve bandwidth. This fast switch can be used for various applications, such as implementing an Optical Time Division Multiplexing (OTDM) network architecture, and providing arbitrary waveform generation (AWG) capability.
FILED Thursday, November 10, 2011
APPL NO 13/373355
ART UNIT 2634 — Digital Communications
CURRENT CPC
Optical communications
398/198
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694085 Reifman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Jaques Reifman (New Market, Maryland);  Maxim Y. Khitrov (Rockville, Maryland);  Andrew T. Reisner (Newtonville, Massachusetts);  Liangyou Chen (Hanover Park, Illinois);  Thomas McKenna (Frederick, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Jaques Reifman (New Market, Maryland);  Maxim Y. Khitrov (Rockville, Maryland);  Andrew T. Reisner (Newtonville, Massachusetts);  Liangyou Chen (Hanover Park, Illinois);  Thomas McKenna (Frederick, Maryland)
ABSTRACT A system is disclosed having a storage, a communications module for interacting with a medical measurement device, an analysis controller, and a test module that allows for the testing and evaluating of decision-support algorithms. A method for testing decision-support algorithms is disclosed having the steps of receiving into storage of a ruggedized, compact computer at least one decision-support algorithm; detecting with a communications module the initiation of a vital-sign monitoring session; receiving and storing vital-sign information into storage by the communications module; pushing the stored vital-sign information by an analysis controller to a test module running the stored at least one decision-support algorithm; and providing at least one output from the decision-support algorithm to at least one of a database and a display.
FILED Saturday, August 06, 2011
APPL NO 13/204657
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
6/523
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US 08694182 Cherepinsky
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Igor Cherepinsky (Sandy Hook, Connecticut)
ASSIGNEE(S) Sikorsky Aircraft Corporation (Stratford, Connecticut)
INVENTOR(S) Igor Cherepinsky (Sandy Hook, Connecticut)
ABSTRACT A flight control system includes an Acceleration and Attitude Command/Velocity Hold mode (AACVH) algorithm which blends attitude commands with acceleration commands. This blending determines a trim attitude for a given rotorcraft flight condition.
FILED Tuesday, April 03, 2007
APPL NO 11/695707
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/7
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694355 Bui et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Hung Bui (Mountain View, California);  Steven Eker (East Palo Alto, California);  Daniel Elenius (San Mateo, California);  Melinda Gervasio (Mountain View, California);  Thomas J. Lee (San Francisco, California);  Mei Marker (Santa Clara, California);  David Morley (Camberwell, Australia);  Janet Murdock (Mountain View, California);  Karen Myers (Menlo Park, California);  Bart Peintner (Palo Alto, California);  Shahin Saadati (Santa Clara, California);  Eric Yeh (Alameda, California);  Neil Yorke-Smith (Mountain View, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Hung Bui (Mountain View, California);  Steven Eker (East Palo Alto, California);  Daniel Elenius (San Mateo, California);  Melinda Gervasio (Mountain View, California);  Thomas J. Lee (San Francisco, California);  Mei Marker (Santa Clara, California);  David Morley (Camberwell, Australia);  Janet Murdock (Mountain View, California);  Karen Myers (Menlo Park, California);  Bart Peintner (Palo Alto, California);  Shahin Saadati (Santa Clara, California);  Eric Yeh (Alameda, California);  Neil Yorke-Smith (Mountain View, California)
ABSTRACT The present invention relates to a method and apparatus for assisting with automated task management. In one embodiment, an apparatus for assisting a user in the execution of a task, where the task includes one or more workflows required to accomplish a goal defined by the user, includes a task learner for creating new workflows from user demonstrations, a workflow tracker for identifying and tracking the progress of a current workflow executing on a machine used by the user, a task assistance processor coupled to the workflow tracker, for generating a suggestion based on the progress of the current workflow, and a task executor coupled to the task assistance processor, for manipulating an application on the machine used by the user to carry out the suggestion.
FILED Monday, June 01, 2009
APPL NO 12/476020
ART UNIT 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/7.270
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US 08694979 Rosu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Marcel C. Rosu (Ossining, New York);  Hanghang Tong (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Marcel C. Rosu (Ossining, New York);  Hanghang Tong (Ossining, New York)
ABSTRACT An embodiment of the invention pertains to a weighted directed graph comprising multiple nodes and edges that each extends between two nodes. The embodiment includes processing edges to generate a forward and reverse edge corresponding to each edge. Forward and reverse edges are processed to generate indirect edges, each comprising two edge components, and extending between two nodes. One node associated with each forward edge, each reverse edge, and each indirect edge is selected to be the key node of its associated edge. All forward, reverse and indirect edges having a particular node as their respective key nodes are placed into a group. All edges of the group are then selectively processed to provide information pertaining to an egonet of the graph that has the particular node as its egonode.
FILED Tuesday, June 26, 2012
APPL NO 13/533697
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/156
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US 08694980 Rosu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Marcel C. Rosu (Ossining, New York);  Hanghang Tong (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Marcel C. Rosu (Ossining, New York);  Hanghang Tong (Ossining, New York)
ABSTRACT An embodiment of the invention pertains to a weighted directed graph comprising multiple nodes and edges that each extends between two nodes. The embodiment includes processing edges to generate a forward and reverse edge corresponding to each edge. Forward and reverse edges are processed to generate indirect edges, each comprising two edge components, and extending between two nodes. One node associated with each forward edge, each reverse edge, and each indirect edge is selected to be the key node of its associated edge. All forward, reverse and indirect edges having a particular node as their respective key nodes are placed into a group. All edges of the group are then selectively processed to provide information pertaining to an egonet of the graph that has the particular node as its egonode.
FILED Thursday, July 12, 2012
APPL NO 13/547656
ART UNIT 2191 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/156
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US 08695109 Schotland et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) John C. Schotland (Ann Arbor, Michigan);  Alexander A. Govyadinov (Warrington, Pennsylvania);  George Y. Panasyuk (Fairborn, Ohio)
ASSIGNEE(S) The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) John C. Schotland (Ann Arbor, Michigan);  Alexander A. Govyadinov (Warrington, Pennsylvania);  George Y. Panasyuk (Fairborn, Ohio)
ABSTRACT A system and method for optically imaging a sample. The method and system uses a controlled scatterer of light positioned in the near field of a sample. The extinguished power from an incident field, which illuminates both the sample and the controlled scatterer, is then measured as a function of the controlled scatterer position and is used to mathematically reconstruct an image of the sample.
FILED Tuesday, October 11, 2011
APPL NO 13/270700
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM]
850/30
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National Science Foundation (NSF) 

US 08690331 Culjat et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Martin Culjat (Los Angeles, California);  Priyamvada Tewari (Los Angeles, California);  Jean L. Bourges (Paris, France);  Jean P. Hubschman (Los Angeles, California);  Rahul S. Singh (Palo Alto, California);  Zachary Taylor (Poway, California);  Warren S. Grundfest (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Martin Culjat (Los Angeles, California);  Priyamvada Tewari (Los Angeles, California);  Jean L. Bourges (Paris, France);  Jean P. Hubschman (Los Angeles, California);  Rahul S. Singh (Palo Alto, California);  Zachary Taylor (Poway, California);  Warren S. Grundfest (Los Angeles, California)
ABSTRACT A corneal hydration sensing system includes an illumination system configured to provide an illumination beam of terahertz radiation, an optical system arranged in an optical path of the illumination system to relay and direct at least a portion of the illumination beam of terahertz radiation onto a cornea of a subject and to receive at least a portion of terahertz radiation reflected from the cornea to provide a return beam of terahertz radiation, and a detection system arranged in an optical path of the return beam of terahertz radiation. The detection system is configured to provide a detection signal from detecting at least a portion of the return beam of terahertz radiation. The corneal hydration sensing system also includes a signal processing system configured to communicate with the detection system to receive the detection signal. The signal processing system processes the detection signal to provide a measure of an amount of hydration sensed in the cornea of the subject.
FILED Wednesday, August 29, 2012
APPL NO 13/597947
ART UNIT 2872 — Optics
CURRENT CPC
Optics: Eye examining, vision testing and correcting
351/221
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US 08690861 Bagwell et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Roger B. Bagwell (Bellefonte, Pennsylvania);  Paul L. Frankhouser (Miami Beach, Florida);  Maureen L. Mulvihill (Bellefonte, Pennsylvania);  Josue R. Crespo (Cabo Rojo, Puerto Rico);  Brian M. Park (Bellefonte, Pennsylvania);  Dana B. Mallen (Yardley, Pennsylvania);  Gabriela Hernandez Meza (Philadelphia, Pennsylvania);  Debora L. Demers (State College, Pennsylvania)
ASSIGNEE(S) Actuated Medical, Inc. (Bellefonte, Pennsylvania)
INVENTOR(S) Roger B. Bagwell (Bellefonte, Pennsylvania);  Paul L. Frankhouser (Miami Beach, Florida);  Maureen L. Mulvihill (Bellefonte, Pennsylvania);  Josue R. Crespo (Cabo Rojo, Puerto Rico);  Brian M. Park (Bellefonte, Pennsylvania);  Dana B. Mallen (Yardley, Pennsylvania);  Gabriela Hernandez Meza (Philadelphia, Pennsylvania);  Debora L. Demers (State College, Pennsylvania)
ABSTRACT A device for the in situ clearing of blockages in a tube includes a controller and a clearing member. The controller can have a housing and an actuator for generating repetitive motion. The clearing member can be releasably coupled to the controller and suitable for insertion in the tube. The tube can be at least partially disposed within a living being. The controller can be located external to the living being. The clearing member can have a first end releasably coupled to the actuator, at least one flexible section which permits axial displacement of the clearing member, and a second end suitable for repetitively engaging and disrupting the blockage. The flexible section permits the clearing member to repetitively engage and disrupt the blockage within one of a straight and a curved portion of the artificial tube.
FILED Thursday, August 09, 2012
APPL NO 13/571104
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
64/540
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US 08691010 Hansen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Carl L. Hansen (Pasadena, California);  Morten Sommer (Copenhagen NV, Denmark);  Stephen R. Quake (San Marino, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Carl L. Hansen (Pasadena, California);  Morten Sommer (Copenhagen NV, Denmark);  Stephen R. Quake (San Marino, California)
ABSTRACT The use of microfluidic structures enables high throughput screening of protein crystallization. In one embodiment, an integrated combinatoric mixing chip allows for precise metering of reagents to rapidly create a large number of potential crystallization conditions, with possible crystal formations observed on chip. In an alternative embodiment, the microfluidic structures may be utilized to explore phase space conditions of a particular protein crystallizing agent combination, thereby identifying promising conditions and allowing for subsequent focused attempts to obtain crystal growth.
FILED Friday, April 15, 2011
APPL NO 13/087697
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/68
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US 08691116 Han et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Moon Gyu Han (Yongin-si, South Korea);  Jay K. Sperry (Pendleton, South Carolina);  Samuel T. Ingram (Seneca, South Carolina);  Stephen H. Foulger (Clemson, South Carolina)
ASSIGNEE(S) Clemson University (Clemson, South Carolina)
INVENTOR(S) Moon Gyu Han (Yongin-si, South Korea);  Jay K. Sperry (Pendleton, South Carolina);  Samuel T. Ingram (Seneca, South Carolina);  Stephen H. Foulger (Clemson, South Carolina)
ABSTRACT Disclosed are conductive polymer inks and methods for forming the inks. The disclosed inks include a dispersion of conductive core/shell nanoparticles. The core/shell nanoparticles include a polymeric core and a shell formed of a conducting polymer. The inks can include a dispersion of the core/shell nanoparticles in a liquid carrier, such as an alcohol. The disclosed inks can be formulated to high viscosities and can be utilized in high-speed printing processes including rotogravure and flexographic printing processes. Products encompassed by the disclosure include polymer devices such as sensors, OFETs, RFID tags, printed circuit board, electrochromic devices, non-volatile memory devices, photovoltaics, and the like.
FILED Friday, March 23, 2007
APPL NO 12/293826
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions
252/500
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US 08691177 Pfeifer et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Peter Pfeifer (Columbia, Missouri);  Galen J. Suppes (Columbia, Missouri);  Parag Shah (Ames, Iowa);  Jacob W. Burress (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Peter Pfeifer (Columbia, Missouri);  Galen J. Suppes (Columbia, Missouri);  Parag Shah (Ames, Iowa);  Jacob W. Burress (Columbia, Missouri)
ABSTRACT The present invention provides a high surface area porous carbon material and a process for making this material. In particular, the carbon material is derived from biomass and has large mesopore and micropore surfaces that promote improved adsorption of materials and gas storage capabilities.
FILED Friday, October 21, 2011
APPL NO 13/278754
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/445.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691178 Forrest et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Communications-Electronics Command (CECOM)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Stephen R. Forrest (Ann Arbor, Michigan);  Jeramy D. Zimmerman (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Jeramy D. Zimmerman (Ann Arbor, Michigan)
ABSTRACT A method of processing bundles of carbon nanotubes (CNTs). Bundles of CNTs are put into a solution and unbundled using sonication and one or more surfactants that break apart and disperse at least some of the bundles into the solution such that it contains individual semiconducting CNTs, individual metallic CNTs, and remaining CNT bundles. The individual CNTs are separated from each other using agarose bead column separation using sodium dodecyl sulfate as a surfactant. Remaining CNT bundles are then separated out by performing density-gradient ultracentrifugation.
FILED Friday, June 03, 2011
APPL NO 13/153382
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/447.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691203 Bettinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
APPLICANT(S) Christopher J. Bettinger (Palo Alto, California);  Joost P. Bruggeman (Schorl, Netherlands);  Lino Da Silva Ferreira (Coimbra, Portugal);  Jeffrey M. Karp (Chestnut Hill, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Christiaan Nijst (Amsterdam, Netherlands);  Andreas Zumbuehl (Nyon, Switzerland);  Jason Burdick (Philadelphia, Pennsylvania);  Sonia J. Kim (West Nyack, New York)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Christopher J. Bettinger (Palo Alto, California);  Joost P. Bruggeman (Schorl, Netherlands);  Lino Da Silva Ferreira (Coimbra, Portugal);  Jeffrey M. Karp (Chestnut Hill, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Christiaan Nijst (Amsterdam, Netherlands);  Andreas Zumbuehl (Nyon, Switzerland);  Jason Burdick (Philadelphia, Pennsylvania);  Sonia J. Kim (West Nyack, New York)
ABSTRACT The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers.
FILED Friday, March 23, 2012
APPL NO 13/428869
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/78.60
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691389 Fu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Peng Fei Fu (Midland, Michigan);  Lingjie Jay Guo (Ann Arbor, Michigan)
ASSIGNEE(S) Dow Corning Corporation (Midland, Michigan)
INVENTOR(S) Peng Fei Fu (Midland, Michigan);  Lingjie Jay Guo (Ann Arbor, Michigan)
ABSTRACT A method of nanopatterning includes the steps of providing the resist film (12) and forming the pattern in the resist film (12). The resist film (12) includes an organosilicone compound having at least two vinyl groups, an organosilicone crosslinker different from the organosilicone compound, a catalyst, and a catalyst inhibitor. The cured resist film (12) includes the reaction product of the organosilicone compound having at least two vinyl groups and the organosilicone crosslinker different from the organosilicone compound, in the presence of the catalyst and the catalyst inhibitor. The article (10) includes a substrate (14), and the cured resist film (12) is disposed on the substrate (14). Due to the presence of the catalyst inhibitor in the resist film (12), the resist film (12) may be manipulated for hours at room temperature without curing. At the same time, the resist film (12) cures in a sufficiently short period of time to be commercially valuable.
FILED Wednesday, November 30, 2005
APPL NO 11/916003
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Stock material or miscellaneous articles
428/447
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691552 Gonzalez et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Ramon Gonzalez (Houston, Texas);  Paul Campbell (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas);  Glycos Biotechnologies, Inc. (Houston, Texas)
INVENTOR(S) Ramon Gonzalez (Houston, Texas);  Paul Campbell (Houston, Texas)
ABSTRACT Glycerol or other reduced carbon sources may be used as a feedstock for the microbial production of chemical products under certain microaerobic conditions. For example, such production may occur under microaerobic or microrespiratory conditions in which electron acceptors are consumed in the reaction as quickly as they are added. In such reactions, the reaction product is at least as reduced as carbon source. Further, during such a reaction, at least some of the carbon source is used to generate cell mass. In addition, microorganisms with modified genomes are provided for carrying out the methods herein.
FILED Wednesday, October 28, 2009
APPL NO 13/126499
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691588 Park et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) Seung-min Park (Albany, California);  Yun Suk Huh (Daejeon, South Korea);  David Erickson (Ithaca, New York);  Harold G. Craighead (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Seung-min Park (Albany, California);  Yun Suk Huh (Daejeon, South Korea);  David Erickson (Ithaca, New York);  Harold G. Craighead (Ithaca, New York)
ABSTRACT A method is provided for fabricating a nanochannel. The method comprises providing a microchannel and controlling collapse of the microchannel so that it collapses to form a nanochannel of desired dimensions. The method employs a collapsible, flexible material such as the elastomer polydimethylsiloxane (PDMS) to form the nanochannel. A master is provided that is configured to have geometric conditions that promote a desired frequency of microchannel collapse. A collapsible material having a stiffness that also promotes a desired frequency of microchannel collapse is molded on the master. The molded collapsible material is removed from the master and bonded to a base, thereby forming the microchannel, which then collapses (or is collapsed) to form the nanochannel of desired dimensions. Nanofluidic and microfluidic devices comprising complex nanochannel structures and micro to nanochannel transitions are also provided.
FILED Friday, August 20, 2010
APPL NO 13/391508
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/94
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691972 Huang
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
U.S. State Government
State of Georgia
APPLICANT(S) Zhen Huang (Marietta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Zhen Huang (Marietta, Georgia)
ABSTRACT Disclosed are compounds of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer. Also disclosed are methods of preparing compound of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer. Further disclosed are methods of counducting drug discovery and research comprises applying the compound of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer in an investigation.
FILED Friday, July 20, 2012
APPL NO 13/553901
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Organic compounds
536/28.540
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692187 Hunt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) Donald F. Hunt (Charlottesville, Virginia);  Joshua J. Coon (Madison, Wisconsin);  John Edward Philip Syka (Charlottesville, Virginia);  Jarod A. Marto (Wayland, Massachusetts)
ASSIGNEE(S) University of Virginia Patent Foundation (, None)
INVENTOR(S) Donald F. Hunt (Charlottesville, Virginia);  Joshua J. Coon (Madison, Wisconsin);  John Edward Philip Syka (Charlottesville, Virginia);  Jarod A. Marto (Wayland, Massachusetts)
ABSTRACT The present invention relates to a new method for fragmenting ions in a mass spectrometer through the use of electron transfer dissociation, and for performing sequence analysis of peptides and proteins by mass spectrometry. In the case of peptides, the invention promotes fragmentation along the peptide backbone and makes it possible to deduce the amino acid sequence of the sample, including modified amino acid residues, through the use of an RF field device.
FILED Friday, March 16, 2012
APPL NO 13/422812
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/282
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692230 Zhou et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Chongwu Zhou (Arcadia, California);  Alexander Badmaev (Hillsboro, Oregon);  Chuan Wang (Albany, California);  Yuchi Che (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Chongwu Zhou (Arcadia, California);  Alexander Badmaev (Hillsboro, Oregon);  Chuan Wang (Albany, California);  Yuchi Che (Los Angeles, California)
ABSTRACT A high performance field-effect transistor includes a substrate, a nanomaterial thin film disposed on the substrate, a source electrode and a drain electrode formed on the nanomaterial thin film, and a channel area defined between the source electrode and the drain electrode. A unitary self-aligned gate electrode extends from the nanomaterial thin film in the channel area between the source electrode and the drain electrode, the gate electrode having an outer dielectric layer and including a foot region and a head region, the foot region in contact with a portion of the nanomaterial thin film in the channel area. A metal layer is disposed over the source electrode, the drain electrode, the head region of the gate electrode, and portions of the nanomaterial thin film proximate the source electrode and the drain electrode in the channel area.
FILED Monday, March 26, 2012
APPL NO 13/430457
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/29
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US 08692575 Gershenfeld et al.
FUNDED BY
Department of Defense (DOD)
Defense MicroElectronics Activity (DMEA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Neil Gershenfeld (Somerville, Massachusetts);  Kailiang Chen (Cambridge, Massachusetts);  David Allen Dalrymple (Columbia, Maryland)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Neil Gershenfeld (Somerville, Massachusetts);  Kailiang Chen (Cambridge, Massachusetts);  David Allen Dalrymple (Columbia, Maryland)
ABSTRACT A family of self-timed, charge-conserving asynchronous logic elements that interact with their nearest neighbors permits design and implementation of circuits that are asynchronous at the bit level. The elements pass information by means of state tokens, rather than voltages. Each cell is self-timed, so no hardware non-local connections are needed. An asynchronous logic element comprises a set of edges for asynchronous communication with at least one neighboring cell, the edges receiving state tokens from neighboring logic elements and transferring output state tokens to neighboring logic elements, and circuitry configured to perform, when the circuitry inputs contain valid tokens and the circuitry outputs are empty, a logic operation utilizing received tokens as inputs, thereby producing an output token reflecting the result of the logic operation.
FILED Tuesday, October 11, 2011
APPL NO 13/271179
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electronic digital logic circuitry
326/38
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US 08692716 Biris et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Alexandru S. Biris (Little Rock, Arkansas);  Hussain Al-Rizzo (Little Rock, Arkansas);  Taha Elwi (Little Rock, Arkansas);  Daniel Rucker (Hot Springs, Arkansas)
ASSIGNEE(S) Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S) Alexandru S. Biris (Little Rock, Arkansas);  Hussain Al-Rizzo (Little Rock, Arkansas);  Taha Elwi (Little Rock, Arkansas);  Daniel Rucker (Hot Springs, Arkansas)
ABSTRACT A method of fabricating an antenna. In one embodiment, the method includes the steps of providing a substrate treated with a plasma treatment, providing a nanoparticle ink comprising nanoparticles, painting the nanoparticle ink on the substrate to form an antenna member in which the nanoparticles are connected, determining a feed point of the antenna member, and attaching an feeding port onto the substrate at the feed point to establish a contact between the feeding port and the antenna member.
FILED Monday, February 16, 2009
APPL NO 12/371769
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Communications: Radio wave antennas
343/700.MS0
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693081 Heikenfeld et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Jason Heikenfeld (Cincinnati, Ohio);  Matthew Hagedon (Cincinnati, Ohio);  Kenneth Dean Andrew (Phoenix, Arizona)
ASSIGNEE(S) University of Cincinnati (Cincinnati, Ohio)
INVENTOR(S) Jason Heikenfeld (Cincinnati, Ohio);  Matthew Hagedon (Cincinnati, Ohio);  Kenneth Dean Andrew (Phoenix, Arizona)
ABSTRACT A device and method of making and using the same. The device includes first and second substrates that are spaced to define a fluid space. Polar and non-polar fluids occupy the fluid space. A first electrode, with a dielectric layer, is positioned on the first substrate and electrically coupled to at least one voltage source, which is configured to supply an electrical bias to the first electrode. The fluid space includes at least one fluid splitting structure that is configured to facilitate the movement of the non-polar fluid into a portion of the polar fluid. Fluid splitting structure assisted movement of the non-polar fluid splits the polar fluid.
FILED Thursday, September 29, 2011
APPL NO 13/248826
ART UNIT 2872 — Optics
CURRENT CPC
Optical: Systems and elements
359/290
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US 08693742 Piestun et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
APPLICANT(S) Rafael Piestun (Golden, Colorado);  Sri Rama Prasanna Pavani (Pasadena, California);  Michael A. Thompson (Orange, California);  Julie S. Biteen (Menlo Park, California);  William E. Moerner (Los Altos, California)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Rafael Piestun (Golden, Colorado);  Sri Rama Prasanna Pavani (Pasadena, California);  Michael A. Thompson (Orange, California);  Julie S. Biteen (Menlo Park, California);  William E. Moerner (Los Altos, California)
ABSTRACT Embodiments of the present invention can resolve molecules beyond the optical diffraction limit in three dimensions. A double-helix point spread function can be used to in conjunction with a microscope to provide dual-lobed images of a molecule. Based on the rotation of the dual-lobed image, the axial position of the molecule can be estimated or determined. In some embodiments, the angular rotation of the dual-lobed imaged can be determined using a centroid fit calculation or by finding the midpoints of the centers of the two lobes. Regardless of the technique, the correspondence between the rotation and axial position can be utilized. A double-helix point spread function can also be used to determine the lateral positions of molecules and hence their three-dimensional location.
FILED Thursday, December 17, 2009
APPL NO 12/640834
ART UNIT 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Image analysis
382/128
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US 08693762 Di Carlo et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Dino Di Carlo (Los Angeles, California);  Aydogan Ozcan (Los Angeles, California);  Bahram Jalali (Los Angeles, California);  Soojung Hur (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dino Di Carlo (Los Angeles, California);  Aydogan Ozcan (Los Angeles, California);  Bahram Jalali (Los Angeles, California);  Soojung Hur (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ABSTRACT A flow cytometry system includes an inertial particle focusing device including a plurality of substantially parallel microchannels formed in a substrate, each microchannel having a width to height ratio in the range of 2:3 to 1:4, an analyzer disposed adjacent the inertial particle focusing device such that the analyzer is configured to detect a characteristic of particles in the inertial particle focusing device, and a controller connected to the analyzer and configured to direct the detection of the characteristic of the particles.
FILED Tuesday, September 13, 2011
APPL NO 13/231570
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/133
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US 08694866 Tamo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Itzhak Tamo (Pasadena, California);  Zhiying Wang (Pasadena, California);  Jehoshua Bruck (La Canada, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Itzhak Tamo (Pasadena, California);  Zhiying Wang (Pasadena, California);  Jehoshua Bruck (La Canada, California)
ABSTRACT MDS (maximum distance separable) array codes are widely used in storage systems to protect data against erasures. The rebuilding ratio problem is addressed and efficient parity codes are proposed. A controller as disclosed is configured for receiving configuration data at the controller that indicates operating features of the array and determining a parity code for operation of the array according to a permutation, wherein the configuration data specifies the array as comprising nodes defined by A=(ai,j) with size rm×k for some integers k,m, and wherein for T={v0 , . . . , Vk-1} Zrm a subset of vectors of size k, where for each v=(v1, . . . , vm)∈T, gcd (v1, . . . , vm, r), where gcd is the greatest common divisor, such that for any l, 0≦l≦r−1, and v ∈T, the code values are determined by the permutation fvl:[0,rm−1]→[0,rm−1]by fvl(x)=x+lv.
FILED Thursday, March 15, 2012
APPL NO 13/421723
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/770
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US 08695109 Schotland et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) John C. Schotland (Ann Arbor, Michigan);  Alexander A. Govyadinov (Warrington, Pennsylvania);  George Y. Panasyuk (Fairborn, Ohio)
ASSIGNEE(S) The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) John C. Schotland (Ann Arbor, Michigan);  Alexander A. Govyadinov (Warrington, Pennsylvania);  George Y. Panasyuk (Fairborn, Ohio)
ABSTRACT A system and method for optically imaging a sample. The method and system uses a controlled scatterer of light positioned in the near field of a sample. The extinguished power from an incident field, which illuminates both the sample and the controlled scatterer, is then measured as a function of the controlled scatterer position and is used to mathematically reconstruct an image of the sample.
FILED Tuesday, October 11, 2011
APPL NO 13/270700
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM]
850/30
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 08689709 Vimalchand et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Pannalal Vimalchand (Birmingham, Alabama);  Guohai Liu (Birmingham, Alabama);  WanWang Peng (Birmingham, Alabama)
ASSIGNEE(S) Southern Company (Birmingham, Alabama)
INVENTOR(S) Pannalal Vimalchand (Birmingham, Alabama);  Guohai Liu (Birmingham, Alabama);  WanWang Peng (Birmingham, Alabama)
ABSTRACT A pressurized transport oxy-combustor with different configurations is disclosed. Substantially pure oxygen is fed to the transport oxy-combustor under pressure to combust fossil fuels, generating steam for power generation. The end product is the flue gas containing substantially pure CO2 after moisture condensation. The low excess oxygen necessary to achieve complete combustion in the combustor is scavenged by adding another fuel so that substantially all oxygen fed to the combustor is completely consumed. The capability to operate the transport oxy-combustor as a circulating fluidized bed combustor at very high solids circulation rates makes it unnecessary to use recycled CO2 or flue gas as a means to moderate and control the combustion temperature. The temperature in the combustor is effectively controlled by relatively cooler circulating solids that enter the combustion zone. A small amount of CO2 is recycled for aeration and to convey solids fuel to the combustor.
FILED Sunday, February 26, 2012
APPL NO 13/405312
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Furnaces
110/245
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US 08689767 Dec et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) John E. Dec (Livermore, California);  Yi Yang (Livermore, California);  Nicolas Dronniou (San Francisco, California)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) John E. Dec (Livermore, California);  Yi Yang (Livermore, California);  Nicolas Dronniou (San Francisco, California)
ABSTRACT A method for the operation of homogeneous charge compression ignition engines (HCCI) using gasoline or similar single-stage ignition fuels. Partial fuel stratification (PFS), intake pressure boosting and controlled BDC-intake temperatures, typically in the range of 95° C. to about 125° C., are used to reduce combustion pressure rise rates (PRR), and therefore, the knocking propensity of homogeneous charge compression ignition engines operating on gasoline or similar fuels.
FILED Monday, September 12, 2011
APPL NO 13/230320
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Internal-combustion engines
123/295
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US 08690988 Iwasaki
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Nu-Iron Technology, LLC (Charlotte, North Carolina)
ASSIGNEE(S) Nu-Iron Technology, LLC (Charlotte, North Carolina)
INVENTOR(S) Iwao Iwasaki (Tokyo, Japan)
ABSTRACT A method for use in production of metallic iron nodules comprising providing a reducible mixture into a hearth furnace for the production of metallic iron nodules, where the reducible mixture comprises a quantity of reducible iron bearing material, a quantity of first carbonaceous reducing material of a size less than about 28 mesh of an amount between about 65 percent and about 95 percent of a stoichiometric amount necessary for complete iron reduction of the reducible iron bearing material, and a quantity of second carbonaceous reducing material with an average particle size greater than average particle size of the first carbonaceous reducing material and a size between about 3 mesh and about 48 mesh of an amount between about 20 percent and about 60 percent of a stoichiometric amount of necessary for complete iron reduction of the reducible iron bearing material.
FILED Tuesday, October 16, 2012
APPL NO 13/653186
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures
075/503
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691129 Zhamu et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Aruna Zhamu (Centerville, Ohio);  Jinjun Shi (Columbus, Ohio);  Jiusheng Guo (Centerville, Ohio);  Bor Z. Jang (Centerville, Ohio)
ASSIGNEE(S) Nanotek Instruments, Inc. (Dayton, Ohio)
INVENTOR(S) Aruna Zhamu (Centerville, Ohio);  Jinjun Shi (Columbus, Ohio);  Jiusheng Guo (Centerville, Ohio);  Bor Z. Jang (Centerville, Ohio)
ABSTRACT A method of producing an electrically conductive composite composition, which is particularly useful for fuel cell bipolar plate applications. The method comprises: (a) providing a supply of expandable graphite powder; (b) providing a supply of a non-expandable powder component comprising a binder or matrix material; (c) blending the expandable graphite with the non-expandable powder component to form a powder mixture wherein the non-expandable powder component is in the amount of between 3% and 60% by weight based on the total weight of the powder mixture; (d) exposing the powder mixture to a temperature sufficient for exfoliating the expandable graphite to obtain a compressible mixture comprising expanded graphite worms and the non-expandable component; (e) compressing the compressible mixture at a pressure within the range of from about 5 psi to about 50,000 psi in predetermined directions into predetermined forms of cohered graphite composite compact; and (f) treating the so-formed cohered graphite composite to activate the binder or matrix material thereby promoting adhesion within the compact to produce the desired composite composition. Preferably, the non-expandable powder component further comprises an isotropy-promoting agent such as non-expandable graphite particles. Further preferably, step (e) comprises compressing the mixture in at least two directions. The method leads to composite plates with exceptionally high thickness-direction electrical conductivity.
FILED Tuesday, May 08, 2007
APPL NO 11/800730
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/105
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691170 Sobolevskiy et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Anatoly Sobolevskiy (Orlando, Florida);  Joseph A. Rossin (Columbus, Ohio)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) Anatoly Sobolevskiy (Orlando, Florida);  Joseph A. Rossin (Columbus, Ohio)
ABSTRACT A multi-stage selective catalytic reduction (SCR) unit (32) provides efficient reduction of NOx and other pollutants from about 50-550° C. in a power plant (19). Hydrogen (24) and ammonia (29) are variably supplied to the SCR unit depending on temperature. An upstream portion (34) of the SCR unit catalyzes NOx+NH3 reactions above about 200° C. A downstream portion (36) catalyzes NOx+H2 reactions below about 260° C., and catalyzes oxidation of NH3, CO, and VOCs with oxygen in the exhaust above about 200° C., efficiently removing NOx and other pollutants over a range of conditions with low slippage of NH3. An ammonia synthesis unit (28) may be connected to the SCR unit to provide NH3 as needed, avoiding transport and storage of ammonia or urea at the site. A carbonaceous gasification plant (18) on site may supply hydrogen and nitrogen to the ammonia synthesis unit, and hydrogen to the SCR unit.
FILED Friday, May 16, 2008
APPL NO 12/122093
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry of inorganic compounds
423/239.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691171 Katz et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) BASF SE (Ludwigshafen, Germany);  Research Triangle Institute (Research Triangle Park, North Carolina)
ASSIGNEE(S) BASF SE (, Germany);  Research Triangle Institute (Research Triangle Park, North Carolina)
INVENTOR(S) Torsten Katz (Neustadt, Germany);  Christian Riemann (Altrip, Germany);  Karsten Bartling (Neustadt, Germany);  Sean Taylor Rigby (Houston, Texas);  Luke James Ivor Coleman (Durham, North Carolina);  Marty Alan Lail (Raleigh, North Carolina)
ABSTRACT A process for removing sulphur oxides from a fluid stream, such as flue gas, comprising: providing a non-aqueous absorption liquid containing at least one hydrophobic amine, the liquid being incompletely miscible with water; treating the fluid stream in an absorption zone with the non-aqueous absorption liquid to transfer at least part of the sulphur oxides into the non-aqueous absorption liquid and to form a sulphur oxide-hydrophobic amine-complex; causing the non-aqueous absorption liquid to be in liquid-liquid contact with an aqueous liquid whereby at least part of the sulphur oxide-hydrophobic amine-complex is hydrolyzed to release the hydrophobic amine and sulphurous hydrolysis products, and at least part of the sulphurous hydrolysis products is transferred into the aqueous liquid; separating the aqueous liquid from the non-aqueous absorption liquid. The process mitigates absorbent degradation problems caused by sulphur dioxide and oxygen in flue gas.
FILED Friday, March 01, 2013
APPL NO 13/782290
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/242.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691180 Zettl et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Alex K. Zettl (Kensington, California);  Thomas D. Yuzvinsky (Berkeley, California);  Adam M. Fennimore (Berkeley, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alex K. Zettl (Kensington, California);  Thomas D. Yuzvinsky (Berkeley, California);  Adam M. Fennimore (Berkeley, California)
ABSTRACT A method for controlled deposition and orientation of molecular sized nanoelectromechanical systems (NEMS) on substrates is disclosed. The method comprised: forming a thin layer of polymer coating on a substrate; exposing a selected portion of the thin layer of polymer to alter a selected portion of the thin layer of polymer; forming a suspension of nanostructures in a solvent, wherein the solvent suspends the nanostructures and activates the nanostructures in the solvent for deposition; and flowing a suspension of nanostructures across the layer of polymer in a flow direction; thereby: depositing a nanostructure in the suspension of nanostructures only to the selected portion of the thin layer of polymer coating on the substrate to form a deposited nanostructure oriented in the flow direction. By selectively employing portions of the method above, complex NEMS may be built of simpler NEMSs components.
FILED Wednesday, August 23, 2006
APPL NO 11/466528
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/461
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691343 Seals et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Roland D Seals (Oak Ridge, Tennessee);  Edward B Ripley (Knoxville, Tennessee);  Russell L Hallman (Knoxville, Tennessee)
ASSIGNEE(S) Babcock and Wilcox Technical Services Y-12, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Roland D Seals (Oak Ridge, Tennessee);  Edward B Ripley (Knoxville, Tennessee);  Russell L Hallman (Knoxville, Tennessee)
ABSTRACT Composite structures having a reinforced material interjoined with a substrate and methods of creating a composite material interjoined with a substrate. In some embodiments the composite structure may be a line or a spot or formed by reinforced material interjoined with the substrate. The methods typically include disposing a precursor material comprising titanium diboride and/or titanium monoboride on at least a portion of the substrate and heating the precursor material and the at least a portion of the substrate in the presence of an oxidation preventative until at least a portion of the precursor material forms reinforced material interjoined with the substrate. The precursor material may be disposed on the substrate as a sheet or a tape or a slurry or a paste. Localized surface heating may be used to heat the precursor material. The reinforced material typically comprises a titanium boron compound, such as titanium monoboride, and preferably comprises β-titanium. The substrate is typically titanium-bearing, iron-bearing, or aluminum-bearing. A welding rod is provided as an embodiment. The welding rod includes a metal electrode and a precursor material is disposed adjacent at least a portion of the metal electrode. A material for use in forming a composite structure is provided. The material typically includes a precursor material that includes one or more materials selected from the following group: titanium diboride and titanium monoboride. The material also typically includes a flux.
FILED Friday, May 16, 2008
APPL NO 12/122024
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Coating processes
427/383.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691447 Pitts et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) J. Roland Pitts (Lakewood, Colorado);  Se-Hee Lee (Louisville, Colorado);  C. Edwin Tracy (Golden, Colorado);  Wenming Li (Milpitas, California)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) J. Roland Pitts (Lakewood, Colorado);  Se-Hee Lee (Louisville, Colorado);  C. Edwin Tracy (Golden, Colorado);  Wenming Li (Milpitas, California)
ABSTRACT Solid state, thin film, electrochemical devices (10) and methods of making the same are disclosed. An exemplary device 10 includes at least one electrode (14) and an electrolyte (16) deposited on the electrode (14). The electrolyte (16) includes at least two homogenous layers of discrete physical properties. The two homogenous layers comprise a first dense layer (15) and a second porous layer (16).
FILED Monday, February 25, 2008
APPL NO 12/293460
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0561 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 10/0565 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691525 Thompson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) David N. Thompson (Idaho Falls, Idaho);  William A. Apel (Jackson, Wyoming);  Vicki S. Thompson (Idaho Falls, Idaho);  Thomas E. Ward (PA Furnace, Pennsylvania)
ABSTRACT A genetically modified organism comprising: at least one nucleic acid sequence and/or at least one recombinant nucleic acid isolated from Alicyclobacillus acidocaldarius and encoding a polypeptide involved in at least partially degrading, cleaving, transporting, metabolizing, or removing polysaccharides, cellulose, lignocellulose, hemicellulose, lignin, starch, sugars, sugar oligomers, carbohydrates, complex carbohydrates, chitin, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups; and at least one nucleic acid sequence and/or at least one recombinant nucleic acid encoding a polypeptide involved in fermenting sugar molecules to a product. Additionally, enzymatic and/or proteinaceous extracts may be isolated from one or more genetically modified organisms. The extracts are utilized to convert biomass into a product. Further provided are methods of converting biomass into products comprising: placing the genetically modified organism and/or enzymatic extracts thereof in fluid contact with polysaccharides, cellulose, lignocellulose, hemicellulose, lignin, starch, sugars, sugar oligomers, carbohydrates, complex carbohydrates, chitin, heteroxylans, glycosides, and/or xylan-, glucan-, galactan-, or mannan-decorating groups.
FILED Friday, June 21, 2013
APPL NO 13/924149
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691539 Jantama et al.
FUNDED BY
Department of Energy (DOE)
Department of Agriculture (USDA)
APPLICANT(S) Kaemwich Jantama (Gainesville, Florida);  Mark John Haupt (Pace, Florida);  Xueli Zhang (Gainesville, Florida);  Jonathan C. Moore (Gainesville, Florida);  Keelnatham T. Shanmugam (Gainesville, Florida);  Lonnie O'Neal Ingram (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Kaemwich Jantama (Gainesville, Florida);  Mark John Haupt (Pace, Florida);  Xueli Zhang (Gainesville, Florida);  Jonathan C. Moore (Gainesville, Florida);  Keelnatham T. Shanmugam (Gainesville, Florida);  Lonnie O'Neal Ingram (Gainesville, Florida)
ABSTRACT Genetically engineered microorganisms have been constructed to produce succinate and malate in mineral salt media in pH-controlled batch fermentations without the addition of plasmids or foreign genes. The subject invention also provides methods of producing succinate and malate comprising the culture of genetically modified microorganisms.
FILED Wednesday, March 19, 2008
APPL NO 12/529826
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/145
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US 08691663 Wanlass
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Mark W. Wanlass (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Mark W. Wanlass (Golden, Colorado)
ABSTRACT A method of processing an epistructure or processing a semiconductor device including associating a conformal and flexible handle with the epistructure and removing the epistructure and handle as a unit from the parent substrate. The method further includes causing the epistructure and handle unit to conform to a shape that differs from the shape the epistructure otherwise inherently assumes upon removal from the parent substrate. A device prepared according to the disclosed methods.
FILED Friday, November 06, 2009
APPL NO 12/613863
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02035 (20130101)
H01L 31/0352 (20130101)
H01L 31/1892 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691919 Pratt
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) Russell Clayton Pratt (Foster City, California)
ASSIGNEE(S) Seeo, Inc. (Hayward, California)
INVENTOR(S) Russell Clayton Pratt (Foster City, California)
ABSTRACT A simple procedure is provided by which the hydroxyl termini of poly(ethylene oxide) can be appended with functional groups to a useful extent by reaction and precipitation. The polymer is dissolved in warmed toluene, treated with an excess of organic base and somewhat less of an excess of a reactive acylating reagent, reacted for several hours, then precipitated in isopropanol so that the product can be isolated as a solid, and salt byproducts are washed away. This procedure enables functionalization of the polymer while not requiring laborious purification steps such as solvent-solvent extraction or dialysis to remove undesirable side products.
FILED Saturday, October 01, 2011
APPL NO 13/251246
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
525/408
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US 08692548 Hoyt et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) David W. Hoyt (Richland, Washington);  Jesse A. Sears, Jr. (Kennewick, Washington);  Romulus V. F. Turcu (Richland, Washington);  Kevin M. Rosso (West Richland, Washington);  Jian Zhi Hu (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) David W. Hoyt (Richland, Washington);  Jesse A. Sears, Jr. (Kennewick, Washington);  Romulus V. F. Turcu (Richland, Washington);  Kevin M. Rosso (West Richland, Washington);  Jian Zhi Hu (Richland, Washington)
ABSTRACT A high-pressure magic angle spinning (MAS) rotor is detailed that includes a high-pressure sample cell that maintains high pressures exceeding 150 bar. The sample cell design minimizes pressure losses due to penetration over an extended period of time.
FILED Thursday, July 28, 2011
APPL NO 13/193172
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/307
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US 08692704 Perkins et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) David Nikolaus Perkins (Albuquerque, New Mexico);  Antonio I. Gonzales (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) David Nikolaus Perkins (Albuquerque, New Mexico);  Antonio I. Gonzales (Albuquerque, New Mexico)
ABSTRACT A set of co-registered coherent change detection (CCD) products is produced from a set of temporally separated synthetic aperture radar (SAR) images of a target scene. A plurality of transformations are determined, which transformations are respectively for transforming a plurality of the SAR images to a predetermined image coordinate system. The transformations are used to create, from a set of CCD products produced from the set of SAR images, a corresponding set of co-registered CCD products.
FILED Friday, September 23, 2011
APPL NO 13/242569
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications: Directive radio wave systems and devices
342/25.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693004 Chandler et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) David W. Chandler (Livermore, California);  Kevin E. Strecker (Oakland, California)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) David W. Chandler (Livermore, California);  Kevin E. Strecker (Oakland, California)
ABSTRACT In an embodiment, a dual-etalon cavity-ring-down frequency-comb spectrometer system is described. A broad band light source is split into two beams. One beam travels through a first etalon and a sample under test, while the other beam travels through a second etalon, and the two beams are recombined onto a single detector. If the free spectral ranges (“FSR”) of the two etalons are not identical, the interference pattern at the detector will consist of a series of beat frequencies. By monitoring these beat frequencies, optical frequencies where light is absorbed may be determined.
FILED Thursday, March 17, 2011
APPL NO 13/050430
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/454
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US 08693629 Sgouros et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) George Sgouros (Ellicott City, Maryland);  Robert Hobbs (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) George Sgouros (Ellicott City, Maryland);  Robert Hobbs (Baltimore, Maryland)
ABSTRACT A computerized method and system for determining an optimum amount of Internal Radionuclide Therapy (IRT) and External Radiation Therapy (XRT) to administer, comprising: obtaining activity image information for an imaged object from a detector; running a Monte Carlo simulation for the activity image information to obtain absorbed dose-rate image information at multiple times; adding the absorbed dose-rate image information from each time to obtain IRT total absorbed dose image information; and utilizing the IRT total dose image information to obtain total dose image information that is equivalent to XRT dose image information in terms of dose-rate, wherein the IRT dose information is converted to equivalent XRT dose information without having to generate BED dose maps.
FILED Thursday, January 14, 2010
APPL NO 12/687670
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/65
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US 08694409 Chassin et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) David P. Chassin (Pasco, Washington);  Robert G. Pratt (Kennewick, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) David P. Chassin (Pasco, Washington);  Robert G. Pratt (Kennewick, Washington)
ABSTRACT Disclosed herein are representative embodiments of methods, apparatus, and systems for distributing a resource (such as electricity) using a resource allocation system. In one exemplary embodiment, a plurality of requests for electricity are received from a plurality of end-use consumers. The requests indicate a requested quantity of electricity and a consumer-requested index value indicative of a maximum price a respective end-use consumer will pay for the requested quantity of electricity. A plurality of offers for supplying electricity are received from a plurality of resource suppliers. The offers indicate an offered quantity of electricity and a supplier-requested index value indicative of a minimum price for which a respective supplier will produce the offered quantity of electricity. A dispatched index value is computed at which electricity is to be supplied based at least in part on the consumer-requested index values and the supplier-requested index values.
FILED Tuesday, September 29, 2009
APPL NO 12/587009
ART UNIT 3695 — Business Methods - Finance/Banking/ Insurance
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/37
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694595 Blocksome
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Bussiness Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael A. Blocksome (Rochester, Minnesota)
ABSTRACT Methods, systems, and products are disclosed for data transfers between nodes in a parallel computer that include: receiving, by an origin DMA on an origin node, a buffer identifier for a buffer containing data for transfer to a target node; sending, by the origin DMA to the target node, a RTS message; transferring, by the origin DMA, a data portion to the target node using a memory FIFO operation that specifies one end of the buffer from which to begin transferring the data; receiving, by the origin DMA, an acknowledgement of the RTS message from the target node; and transferring, by the origin DMA in response to receiving the acknowledgement, any remaining data portion to the target node using a direct put operation that specifies the other end of the buffer from which to begin transferring the data, including initiating the direct put operation without invoking an origin processing core.
FILED Wednesday, November 07, 2012
APPL NO 13/671055
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/212
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National Aeronautics and Space Administration (NASA) 

US 08689556 Jones et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Jack A. Jones (Los Angeles, California);  Yi Chao (Pasadena, California);  Thomas I. Valdez (Covina, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Jack A. Jones (Los Angeles, California);  Yi Chao (Pasadena, California);  Thomas I. Valdez (Covina, California)
ABSTRACT An energy producing device, for example a submersible vehicle for descending or ascending to different depths within water or ocean, is disclosed. The vehicle comprises a temperature-responsive material to which a hydraulic fluid is associated. A pressurized storage compartment stores the fluid as soon as the temperature-responsive material changes density. The storage compartment is connected with a hydraulic motor, and a valve allows fluid passage from the storage compartment to the hydraulic motor. An energy storage component, e.g. a battery, is connected with the hydraulic motor and is charged by the hydraulic motor when the hydraulic fluid passes through the hydraulic motor. Upon passage in the hydraulic motor, the fluid is stored in a further storage compartment and is then sent back to the area of the temperature-responsive material.
FILED Tuesday, June 28, 2011
APPL NO 13/170400
ART UNIT 3748 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Power plants
060/641.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691068 Huang et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) Cunping Huang (Cocoa, Florida);  Ali T-Raissi (Melbourne, Florida);  Nazim Muradov (Melbourne, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Cunping Huang (Cocoa, Florida);  Ali T-Raissi (Melbourne, Florida);  Nazim Muradov (Melbourne, Florida)
ABSTRACT Two classes of hybrid/thermochemical water splitting processes for the production of hydrogen and oxygen have been proposed based on (1) metal sulfate-ammonia cycles (2) metal pyrosulfate-ammonia cycles. Methods and systems for a metal sulfate MSO4—NH3 cycle for producing H2 and O2 from a closed system including feeding an aqueous (NH3)4SO3 solution into a photoctalytic reactor to oxidize the aqueous (NH3)4SO3 into aqueous (NH3)2SO4 and reduce water to hydrogen, mixing the resulting aqueous (NH3)2SO4 with metal oxide (e.g. ZnO) to form a slurry, heating the slurry of aqueous (NH4)2SO4 and ZnO(s) in the low temperature reactor to produce a gaseous mixture of NH3 and H2O and solid ZnSO4(s), heating solid ZnSO4 at a high temperature reactor to produce a gaseous mixture of SO2 and O2 and solid product ZnO, mixing the gaseous mixture of SO2 and O2 with an NH3 and H2O stream in an absorber to form aqueous (NH4)2SO3 solution and separate O2 for aqueous solution, recycling the resultant solution back to the photoreactor and sending ZnO to mix with aqueous (NH4)2SO4 solution to close the water splitting cycle wherein gaseous H2 and O2 are the only products output from the closed ZnSO4—NH3 cycle.
FILED Saturday, November 08, 2008
APPL NO 12/267569
ART UNIT 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 17/504 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 1/003 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691104 Greer et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Harold F. Greer (Pasadena, California);  Julia R. Greer (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Harold F. Greer (Pasadena, California);  Julia R. Greer (Pasadena, California)
ABSTRACT A method of controlling wetting characteristics is described. Such method includes forming and configuring nanostructures on a surface where controlling of the wetting characteristics is desired. Surfaces and methods of fabricating such surfaces are also described.
FILED Friday, January 13, 2012
APPL NO 13/350734
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Etching a substrate: Processes
216/59
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US 08691385 Littman et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
Department of Transportation (USDOT)
U.S. State Government
State of New York
APPLICANT(S) Howard Littman (Niskayuna, New York);  Joel L. Plawsky (Albany, New York);  John D. Paccione (Voorheesville, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Howard Littman (Niskayuna, New York);  Joel L. Plawsky (Albany, New York);  John D. Paccione (Voorheesville, New York)
ABSTRACT Methods and apparatus for coating particulate material are provided. The apparatus includes a vessel having a top and a bottom, a vertically extending conduit having an inlet in the vessel and an outlet outside of the vessel, a first fluid inlet in the bottom of the vessel for introducing a transfer fluid, a second fluid inlet in the bottom of the vessel for introducing a coating fluid, and a fluid outlet from the vessel. The method includes steps of agitating a material, contacting the material with a coating material, and drying the coating material to produce a coated material. The invention may be adapted to coat aerogel beads, among other materials. A coated aerogel bead and an aerogel-based insulation material are also disclosed.
FILED Wednesday, July 18, 2012
APPL NO 13/552305
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/407
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US 08691612 Kim et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Hyun-Jung Kim (Poquoson, Virginia);  Sang Hyouk Choi (Poquoson, Virginia);  Glen C. King (Williamsburg, Virginia);  Yeonjoon Park (Yorktown, Virginia);  Kunik Lee (Troy, Michigan)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Hyun-Jung Kim (Poquoson, Virginia);  Sang Hyouk Choi (Poquoson, Virginia);  Glen C. King (Williamsburg, Virginia);  Yeonjoon Park (Yorktown, Virginia);  Kunik Lee (Troy, Michigan)
ABSTRACT Provided is a method of enhancing thermoelectric performance by surrounding crystalline semiconductors with nanoparticles by contacting a bismuth telluride material with a silver salt under a substantially inert atmosphere and a temperature approximately near the silver salt decomposition temperature; and recovering a metallic bismuth decorated material comprising silver telluride crystal grains.
FILED Monday, March 05, 2012
APPL NO 13/411793
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/54
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US 08692562 Woodard
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Marie Woodard (Hampton, Virginia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Stanley E. Woodard (Hampton, Virginia)
ABSTRACT A wireless in-plane strain and displacement sensor includes an electrical conductor fixedly coupled to a substrate subject to strain conditions. The electrical conductor is shaped between its ends for storage of an electric field and a magnetic field, and remains electrically unconnected to define an unconnected open-circuit having inductance and capacitance. In the presence of a time-varying magnetic field, the electrical conductor so-shaped resonates to generate harmonic electric and magnetic field responses. The sensor also includes at least one electrically unconnected electrode having an end and a free portion extending from the end thereof. The end of each electrode is fixedly coupled to the substrate and the free portion thereof remains unencumbered and spaced apart from a portion of the electrical conductor so-shaped. More specifically, at least some of the free portion is disposed at a location lying within the magnetic field response generated by the electrical conductor. A motion guidance structure is slidingly engaged with each electrode's free portion in order to maintain each free portion parallel to the electrical conductor so-shaped.
FILED Monday, August 01, 2011
APPL NO 13/195251
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/629
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692999 Olczak
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Eugene Olczak (Pittsford, New York)
ASSIGNEE(S) Exelis, Inc. (McLean, Virginia)
INVENTOR(S) Eugene Olczak (Pittsford, New York)
ABSTRACT A method of minimizing fringe print-through in a phase-shifting interferometer, includes the steps of: (a) determining multiple transfer functions of pixels in the phase-shifting interferometer; (b) computing a crosstalk term for each transfer function; and (c) displaying, to a user, a phase-difference map using the crosstalk terms computed in step (b). Determining a transfer function in step (a) includes measuring intensities of a reference beam and a test beam at the pixels, and measuring an optical path difference between the reference beam and the test beam at the pixels. Computing crosstalk terms in step (b) includes computing an N-dimensional vector, where N corresponds to the number of transfer functions, and the N-dimensional vector is obtained by minimizing a variance of a modulation function in phase shifted images.
FILED Thursday, June 23, 2011
APPL NO 13/167078
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693002 Campbell
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Joel F. Campbell (Poquoson, Virginia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Joel F. Campbell (Poquoson, Virginia)
ABSTRACT A Fourier transform spectrometer (FTS) data acquisition system includes an FTS spectrometer that receives a spectral signal and a laser signal. The system further includes a wideband detector, which is in communication with the FTS spectrometer and receives the spectral signal and laser signal from the FTS spectrometer. The wideband detector produces a composite signal comprising the laser signal and the spectral signal. The system further comprises a converter in communication with the wideband detector to receive and digitize the composite signal. The system further includes a signal processing unit that receives the composite signal from the converter. The signal processing unit further filters the laser signal and the spectral signal from the composite signal and demodulates the laser signal, to produce velocity corrected spectral data.
FILED Tuesday, December 21, 2010
APPL NO 12/974359
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/451
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US 08693828 Wollack et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Edward J. Wollack (Clarksville, Maryland);  Kongpop U-Yen (Arlington, Virginia);  David T. Chuss (Bowie, Maryland)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics Space Administration (Washington, District of Columbia)
INVENTOR(S) Edward J. Wollack (Clarksville, Maryland);  Kongpop U-Yen (Arlington, Virginia);  David T. Chuss (Bowie, Maryland)
ABSTRACT A waveguide structure for a dual polarization waveguide includes a first flange member, a second flange member, and a waveguide member disposed in each of the first flange member and second flange member. The first flange member and the second flange member are configured to be coupled together in a spaced-apart relationship separated by a gap. The first flange member has a substantially smooth surface, and the second flange member has an array of two-dimensional pillar structures formed therein.
FILED Tuesday, May 10, 2011
APPL NO 13/104538
ART UNIT 2883 — Optics
CURRENT CPC
Optical waveguides
385/50
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US 08693973 Chattopadhyay et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Goutam Chattopadhyay (Pasadena, California);  Erich T. Schlecht (Pasadena, California);  Choonsup Lee (La Palma, California);  Robert H. Lin (Chino, California);  John J. Gill (La Crescenta, California);  Seth Sin (Pasadena, California);  Imran Mehdi (South Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Goutam Chattopadhyay (Pasadena, California);  Erich T. Schlecht (Pasadena, California);  Choonsup Lee (La Palma, California);  Robert H. Lin (Chino, California);  John J. Gill (La Crescenta, California);  Seth Sin (Pasadena, California);  Imran Mehdi (South Pasadena, California)
ABSTRACT A coplanar waveguide (CPW) based subharmonic mixer working at 670 GHz using GaAs Schottky diodes. One example of the mixer has a LO input, an RF input and an IF output. Another possible mixer has a LO input, and IF input and an RF output. Each input or output is connected to a coplanar waveguide with a matching network. A pair of antiparallel diodes provides a signal at twice the LO frequency, which is then mixed with a second signal to provide signals having sum and difference frequencies. The output signal of interest is received after passing through a bandpass filter tuned to the frequency range of interest.
FILED Wednesday, May 02, 2012
APPL NO 13/462679
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Telecommunications
455/325
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US 08694183 Kelley
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Gary Wayne Kelley (Huntsville, Alabama)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Gary Wayne Kelley (Huntsville, Alabama)
ABSTRACT The present invention is a Partial Automated Alignment and Integration System (PAAIS) used to automate the alignment and integration of space vehicle components. A PAAIS includes ground support apparatuses, a track assembly with a plurality of energy-emitting components and an energy-receiving component containing a plurality of energy-receiving surfaces. Communication components and processors allow communication and feedback through PAAIS.
FILED Tuesday, December 06, 2011
APPL NO 13/312481
ART UNIT 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/13
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 08691219 Martin et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Phyllis A. W. Martin (Lanham, Maryland);  Ashaki D. S. Shropshire (Washington, District of Columbia);  Dawn E. Gundersen-Rindal (Silver Springs, Maryland);  Michael B. Blackburn (Woodbine, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Phyllis A. W. Martin (Lanham, Maryland);  Ashaki D. S. Shropshire (Washington, District of Columbia);  Dawn E. Gundersen-Rindal (Silver Springs, Maryland);  Michael B. Blackburn (Woodbine, Maryland)
ABSTRACT Chromobacterium subtsugae sp. nov., a new species of the genus Chromobacterium which possesses insecticidal activity, is described. The invention also relates to insecticidally-active metabolites obtained from the strain and to insecticidal compositions comprising cultures of the strain and/or supernatants, filtrates, and extracts obtained from the strain, and use thereof to control insect pests.
FILED Thursday, February 08, 2007
APPL NO 11/704565
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691539 Jantama et al.
FUNDED BY
Department of Energy (DOE)
Department of Agriculture (USDA)
APPLICANT(S) Kaemwich Jantama (Gainesville, Florida);  Mark John Haupt (Pace, Florida);  Xueli Zhang (Gainesville, Florida);  Jonathan C. Moore (Gainesville, Florida);  Keelnatham T. Shanmugam (Gainesville, Florida);  Lonnie O'Neal Ingram (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Kaemwich Jantama (Gainesville, Florida);  Mark John Haupt (Pace, Florida);  Xueli Zhang (Gainesville, Florida);  Jonathan C. Moore (Gainesville, Florida);  Keelnatham T. Shanmugam (Gainesville, Florida);  Lonnie O'Neal Ingram (Gainesville, Florida)
ABSTRACT Genetically engineered microorganisms have been constructed to produce succinate and malate in mineral salt media in pH-controlled batch fermentations without the addition of plasmids or foreign genes. The subject invention also provides methods of producing succinate and malate comprising the culture of genetically modified microorganisms.
FILED Wednesday, March 19, 2008
APPL NO 12/529826
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/145
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691552 Gonzalez et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Ramon Gonzalez (Houston, Texas);  Paul Campbell (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas);  Glycos Biotechnologies, Inc. (Houston, Texas)
INVENTOR(S) Ramon Gonzalez (Houston, Texas);  Paul Campbell (Houston, Texas)
ABSTRACT Glycerol or other reduced carbon sources may be used as a feedstock for the microbial production of chemical products under certain microaerobic conditions. For example, such production may occur under microaerobic or microrespiratory conditions in which electron acceptors are consumed in the reaction as quickly as they are added. In such reactions, the reaction product is at least as reduced as carbon source. Further, during such a reaction, at least some of the carbon source is used to generate cell mass. In addition, microorganisms with modified genomes are provided for carrying out the methods herein.
FILED Wednesday, October 28, 2009
APPL NO 13/126499
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/252.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691943 Lillehoj et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Hyun Soon Lillehoj (West Friendship, Maryland);  Sung Hyen Lee (Laurel, Maryland);  Yeong ho Hong (Geumjeong-dong Gunpo, South Korea)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Hyun Soon Lillehoj (West Friendship, Maryland);  Sung Hyen Lee (Laurel, Maryland);  Yeong ho Hong (Geumjeong-dong Gunpo, South Korea)
ABSTRACT NK-2 synthetic peptide derived from cationic core region of porcine NK-lysin has an antimicrobial and antitumor polypeptide that is considered to play a pivotal role in innate defense immunity. To evaluate the antimicrobial properties of synthetic chicken NK-lysin peptides, we investigated cytolytic activity against apicomplexan parasites like Eimeria sporozoites, Neospora tachyzoites and Cryptosporidum sporozoites. The chicken NK-2 (cNK-2) lytic peptide which corresponds to amino acid residues of porcine NK-2 peptide significantly disrupted Eimeria and Cryptosporidum sporozoites and Neospora tachyzoites. In contrast, no bactericidal activity was observed on E. coli BMH71-18. The cNK-2 lytic peptide is novel antimicrobial agent which can be used to intervene and treat economically costly infections in the animal industry.
FILED Thursday, March 24, 2011
APPL NO 13/071112
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/324
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692053 Hill et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Curtis B. Hill (Champaign, Illinois);  Glen L. Hartman (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Curtis B. Hill (Champaign, Illinois);  Glen L. Hartman (Urbana, Illinois)
ABSTRACT An Aphis glycines resistance Rag2 gene is provided herein, along with methods for identifying its presence using marker-assisted selection. A cultivar of G. max having resistance to Aphis glycines conferred by the Rag2 gene has been identified. The Rag2 gene, as well as the methods, aphid-resistant varieties, and markers disclosed herein may be used to breed new elite lines expressing soybean aphid resistance.
FILED Wednesday, January 12, 2011
APPL NO 13/005372
ART UNIT 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/266
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692064 Nguyen et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Henry T. Nguyen (Columbia, Missouri);  David A. Sleper (Columbia, Missouri);  James G. Shannon (Kennett, Missouri);  Tri D. Vuong (Columbia, Missouri);  Xiaolei Wu (Cary, North Carolina)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Henry T. Nguyen (Columbia, Missouri);  David A. Sleper (Columbia, Missouri);  James G. Shannon (Kennett, Missouri);  Tri D. Vuong (Columbia, Missouri);  Xiaolei Wu (Cary, North Carolina)
ABSTRACT Several QTLs that are genetically linked to resistance to soybean cyst nematode (SCN) are disclosed. These QTLs have been mapped to genomic regions on Chrs. 4, 8, 10, 11, 18, and 20 of soybean, G. max. Candidate genes underlying these QTLs as defined by the flanking markers, as well as genetic markers associated with these QTLs are also disclosed. These markers can be utilized for introgressing SCN resistance into non-resistant soybean germplasm. The unique resistance genes can be introduced into a non-resistant plant by marker-assisted selection (MAS) or by transgenic methods.
FILED Saturday, October 02, 2010
APPL NO 12/896864
ART UNIT 1661 — Plants
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/278
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 08691129 Zhamu et al.
FUNDED BY
Department of Energy (DOE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Aruna Zhamu (Centerville, Ohio);  Jinjun Shi (Columbus, Ohio);  Jiusheng Guo (Centerville, Ohio);  Bor Z. Jang (Centerville, Ohio)
ASSIGNEE(S) Nanotek Instruments, Inc. (Dayton, Ohio)
INVENTOR(S) Aruna Zhamu (Centerville, Ohio);  Jinjun Shi (Columbus, Ohio);  Jiusheng Guo (Centerville, Ohio);  Bor Z. Jang (Centerville, Ohio)
ABSTRACT A method of producing an electrically conductive composite composition, which is particularly useful for fuel cell bipolar plate applications. The method comprises: (a) providing a supply of expandable graphite powder; (b) providing a supply of a non-expandable powder component comprising a binder or matrix material; (c) blending the expandable graphite with the non-expandable powder component to form a powder mixture wherein the non-expandable powder component is in the amount of between 3% and 60% by weight based on the total weight of the powder mixture; (d) exposing the powder mixture to a temperature sufficient for exfoliating the expandable graphite to obtain a compressible mixture comprising expanded graphite worms and the non-expandable component; (e) compressing the compressible mixture at a pressure within the range of from about 5 psi to about 50,000 psi in predetermined directions into predetermined forms of cohered graphite composite compact; and (f) treating the so-formed cohered graphite composite to activate the binder or matrix material thereby promoting adhesion within the compact to produce the desired composite composition. Preferably, the non-expandable powder component further comprises an isotropy-promoting agent such as non-expandable graphite particles. Further preferably, step (e) comprises compressing the mixture in at least two directions. The method leads to composite plates with exceptionally high thickness-direction electrical conductivity.
FILED Tuesday, May 08, 2007
APPL NO 11/800730
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/105
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693582 Eliezer et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) XW LLC (Dallas, Texas)
ASSIGNEE(S) XW LLC (Dallas, Texas)
INVENTOR(S) Oren E. Eliezer (Plano, Texas);  Dennis I. Robbins (Richardson, Texas);  Thomas Jung (Dallas, Texas)
ABSTRACT A novel and useful multi-antenna receiver that receives, demodulates and decodes a broadcast signal, whose modulation and encoding of time and timing information allow for reliable and power-efficient operation. The multi-antenna receiver of the present invention is adapted to eliminate or substantially reduce the reception nulls that occur in receivers having a single antenna that is placed in a fixed position. Two or more antennas are employed whereby the receiver generates a combined signal based on a combination of the individual antenna signals or selects one of the antenna signals for input to the receiver based on desired criteria such as signal-to-noise-and-interference-ratio (SNIR). This results in greater robustness of the communication link by reducing or eliminating reception nulls and by rejecting interference through the selection of the antenna for which the signal-to-interference ratio is higher. The invention includes various antenna configurations that are adapted to reuse a single core for multiple antennas or to otherwise reduce size and/or cost.
FILED Monday, February 11, 2013
APPL NO 13/764049
ART UNIT 2633 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/320
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693720 Parkins
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) John W. Parkins (Ithaca, New York)
ASSIGNEE(S) Red Tail Hawk Corporation (Itaca, New York)
INVENTOR(S) John W. Parkins (Ithaca, New York)
ABSTRACT An improved wireless communications earplug for use with a magnetic field transmitter. The wireless earplug has a receiver made of a coil of wire on a magnetic bobbin, mounted in close proximity or in contact with a magnetic case of a speaker. The magnetic case of the speaker serves to increase the magnetic flux through the receiver and improves the efficiency of the earplug. The speaker is acoustically coupled to an eartip, and the earplug may be molded into a custom earplug body.
FILED Thursday, July 08, 2010
APPL NO 12/832363
ART UNIT 2654 — Audio Signals
CURRENT CPC
Electrical audio signal processing systems and devices
381/331
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 08692277 Slater, Jr. et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S) David B. Slater, Jr. (Raleigh, North Carolina);  Robert C. Glass (Chapel Hill, North Carolina);  Charles M. Swoboda (Morrisville, North Carolina);  Bernd Keller (Goleta, California);  James Ibbetson (Goleta, California);  Brian Thibeault (Santa Barbara, California);  Eric J. Tarsa (Goleta, California)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) David B. Slater, Jr. (Raleigh, North Carolina);  Robert C. Glass (Chapel Hill, North Carolina);  Charles M. Swoboda (Morrisville, North Carolina);  Bernd Keller (Goleta, California);  James Ibbetson (Goleta, California);  Brian Thibeault (Santa Barbara, California);  Eric J. Tarsa (Goleta, California)
ABSTRACT Light emitting diodes include a diode region comprising a gallium nitride-based n-type layer, an active region and a gallium nitride-based p-type layer. A substrate is provided on the gallium nitride-based n-type layer and optically matched to the diode region. The substrate has a first face remote from the gallium nitride-based n-type layer, a second face adjacent the gallium nitride-based n-type layer and a sidewall therebetween. At least a portion of the sidewall is beveled, so as to extend oblique to the first and second faces. A reflector may be provided on the gallium nitride-based p-type layer opposite the substrate. Moreover, the diode region may be wider than the second face of the substrate and may include a mesa remote from the first face that is narrower than the first face and the second face.
FILED Tuesday, July 13, 2010
APPL NO 12/835366
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/99
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08693582 Eliezer et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) XW LLC (Dallas, Texas)
ASSIGNEE(S) XW LLC (Dallas, Texas)
INVENTOR(S) Oren E. Eliezer (Plano, Texas);  Dennis I. Robbins (Richardson, Texas);  Thomas Jung (Dallas, Texas)
ABSTRACT A novel and useful multi-antenna receiver that receives, demodulates and decodes a broadcast signal, whose modulation and encoding of time and timing information allow for reliable and power-efficient operation. The multi-antenna receiver of the present invention is adapted to eliminate or substantially reduce the reception nulls that occur in receivers having a single antenna that is placed in a fixed position. Two or more antennas are employed whereby the receiver generates a combined signal based on a combination of the individual antenna signals or selects one of the antenna signals for input to the receiver based on desired criteria such as signal-to-noise-and-interference-ratio (SNIR). This results in greater robustness of the communication link by reducing or eliminating reception nulls and by rejecting interference through the selection of the antenna for which the signal-to-interference ratio is higher. The invention includes various antenna configurations that are adapted to reuse a single core for multiple antennas or to otherwise reduce size and/or cost.
FILED Monday, February 11, 2013
APPL NO 13/764049
ART UNIT 2633 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/320
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 08691556 Brophy et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Colleen M. Brophy (Nashville, Tennessee);  Padmini Komalavilas (Nashville, Tennessee);  Joyce Cheung-Flynn (Nashville, Tennessee);  Kyle M. Hocking (Nashville, Tennessee);  Susan S. Eagle (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Colleen M. Brophy (Nashville, Tennessee);  Padmini Komalavilas (Nashville, Tennessee);  Joyce Cheung-Flynn (Nashville, Tennessee);  Kyle M. Hocking (Nashville, Tennessee);  Susan S. Eagle (Nashville, Tennessee)
ABSTRACT The leading cause of graft failure is the subsequent development of intimal hyperplasia, which represents a response to injury that is thought to involve smooth muscle proliferation, migration, phenotypic modulation, and extracellular matrix (ECM) deposition. Surgical techniques typically employed for vein harvest—stretching the vein, placing the vein in low pH, solutions, and the use of toxic surgical skin markers—are shown here to cause injury. The invention therefore provides for non-toxic surgical markers than also protect against stretch-induced loss of functional viability, along with other additives. Devices and compositions for reducing physical stress or protecting from the effects flowing therefrom, also are provided.
FILED Wednesday, December 08, 2010
APPL NO 12/963375
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/284.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691942 Schally et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) Andrew V. Schally (Miami Beach, Florida);  Marta Zarandi (Miami Beach, Florida);  Jozsef L. Varga (Miami Beach, Florida);  Ren Zhi Cai (Miami, Florida)
ASSIGNEE(S) University of Miami (Miami, Florida);  U.S.A. Represented by the Dept. of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Andrew V. Schally (Miami Beach, Florida);  Marta Zarandi (Miami Beach, Florida);  Jozsef L. Varga (Miami Beach, Florida);  Ren Zhi Cai (Miami, Florida)
ABSTRACT There is provided a novel series of synthetic analogs of hGH-RH(1-29)NH2 (SEQ ID NO: 1) and hGH-RH(1-30)NH2. Of particular interest are those carrying PhAc, N-Me-Aib, Dca, Ac-Ada, Fer, Ac-Amc, Me-NH-Sub, PhAc-Ada, Ac-Ada-D-Phe, Ac-Ada-Phe, Dca-Ada, Dca-Amc, Nac-Ada, Ada-Ada, or CH3—(CH2)10—CO-Ada, at the N-Terminus and β-Ala, Amc, Apa, Ada, AE2A, AE4P, ε-Lys(α-NH2), Agm, Lys(Oct) or Ahx, at the C-terminus. These analogs inhibit the release of growth hormone from the pituitary in mammals as well as inhibit the proliferation of human cancers, and inhibit the hyperplastic and benign proliferative disorders of various organs, through a direct effect on the cancerous and non-malignant cells. The stronger inhibitory potencies of the new analogs, as compared to previously described ones, result from replacement of various amino acids.
FILED Saturday, September 25, 2010
APPL NO 12/890626
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/25 (20130101)

Peptides
C07K 14/60 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08689437 Dang et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Bing Dang (Chappaqua, New York);  David Hirsch Danovitch (Granby, Canada);  Mario John Interrante (New Paltz, New York);  John Ulrich Knickerbocker (Monroe, New York);  Michael Jay Shapiro (Austin, New York);  Van Thanh Truong (Brossard, Canada)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Bing Dang (Chappaqua, New York);  David Hirsch Danovitch (Granby, Canada);  Mario John Interrante (New Paltz, New York);  John Ulrich Knickerbocker (Monroe, New York);  Michael Jay Shapiro (Austin, New York);  Van Thanh Truong (Brossard, Canada)
ABSTRACT A method for forming an integrated circuit assembly comprises forming first solder bumps on a first die, and forming a first structure comprising the first die, the first solder bumps, a first flux, and a first substratum. The first die is placed upon the first substratum. The first solder bumps are between the first die and the first substratum. The first flux holds the first die substantially flat and onto the first substratum.
FILED Wednesday, June 24, 2009
APPL NO 12/490804
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/842
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692276 Doany et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Fuad E. Doany (Katonah, New York);  Christopher V. Jahnes (Saddle River, New Jersey);  Clint L. Schow (Ossining, New York);  Mehmet Soyuer (Stamford, Connecticut);  Alexander V. Rylyakov (Mount Kisco, New York)
ABSTRACT A silicon-on-insulator wafer is provided. The silicon-on-insulator wafer includes a silicon substrate having optical vias formed therein. In addition, an optically transparent oxide layer is disposed on the silicon substrate and the optically transparent oxide layer is in contact with the optical vias. Then, a complementary metal-oxide-semiconductor layer is formed over the optically transparent oxide layer.
FILED Monday, July 22, 2013
APPL NO 13/947906
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/98
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 08691385 Littman et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
Department of Transportation (USDOT)
U.S. State Government
State of New York
APPLICANT(S) Howard Littman (Niskayuna, New York);  Joel L. Plawsky (Albany, New York);  John D. Paccione (Voorheesville, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Howard Littman (Niskayuna, New York);  Joel L. Plawsky (Albany, New York);  John D. Paccione (Voorheesville, New York)
ABSTRACT Methods and apparatus for coating particulate material are provided. The apparatus includes a vessel having a top and a bottom, a vertically extending conduit having an inlet in the vessel and an outlet outside of the vessel, a first fluid inlet in the bottom of the vessel for introducing a transfer fluid, a second fluid inlet in the bottom of the vessel for introducing a coating fluid, and a fluid outlet from the vessel. The method includes steps of agitating a material, contacting the material with a coating material, and drying the coating material to produce a coated material. The invention may be adapted to coat aerogel beads, among other materials. A coated aerogel bead and an aerogel-based insulation material are also disclosed.
FILED Wednesday, July 18, 2012
APPL NO 13/552305
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/407
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08691972 Huang
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
U.S. State Government
State of Georgia
APPLICANT(S) Zhen Huang (Marietta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Zhen Huang (Marietta, Georgia)
ABSTRACT Disclosed are compounds of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer. Also disclosed are methods of preparing compound of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer. Further disclosed are methods of counducting drug discovery and research comprises applying the compound of formula (I), a derivative, or a tautomer thereof, or a pharmaceutically acceptable salt of said compound or said tautomer in an investigation.
FILED Friday, July 20, 2012
APPL NO 13/553901
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Organic compounds
536/28.540
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 08693735 Kielkopf et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) John F. Kielkopf (Louisville, Kentucky);  Jeffrey Hay (Louisville, Kentucky)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) John F. Kielkopf (Louisville, Kentucky);  Jeffrey Hay (Louisville, Kentucky)
ABSTRACT A non-contact sensing system for measuring and analyzing an object's position, motion, and/or resonance utilizes optical capturing of image features, data extraction, and signal processing to determine changes in the object's motion or position according to changes in signals, which are associated with the excitation of photons due to the object's motion.
FILED Thursday, March 01, 2012
APPL NO 13/410156
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/107
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 08691385 Littman et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
Department of Transportation (USDOT)
U.S. State Government
State of New York
APPLICANT(S) Howard Littman (Niskayuna, New York);  Joel L. Plawsky (Albany, New York);  John D. Paccione (Voorheesville, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Howard Littman (Niskayuna, New York);  Joel L. Plawsky (Albany, New York);  John D. Paccione (Voorheesville, New York)
ABSTRACT Methods and apparatus for coating particulate material are provided. The apparatus includes a vessel having a top and a bottom, a vertically extending conduit having an inlet in the vessel and an outlet outside of the vessel, a first fluid inlet in the bottom of the vessel for introducing a transfer fluid, a second fluid inlet in the bottom of the vessel for introducing a coating fluid, and a fluid outlet from the vessel. The method includes steps of agitating a material, contacting the material with a coating material, and drying the coating material to produce a coated material. The invention may be adapted to coat aerogel beads, among other materials. A coated aerogel bead and an aerogel-based insulation material are also disclosed.
FILED Wednesday, July 18, 2012
APPL NO 13/552305
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/407
VIEW PATENT @ USPTO:  Full Text   PDF 

Federal Reserve Bank (FED) 

US 08694424 Fraher et al.
FUNDED BY
Federal Reserve Bank (FED)
APPLICANT(S) Richard M. Fraher (Marietta, Georgia);  Larry Schulz (Atlanta, Georgia)
ASSIGNEE(S) Federal Reserve Bank of Atlanta (Atlanta, Georgia)
INVENTOR(S) Richard M. Fraher (Marietta, Georgia);  Larry Schulz (Atlanta, Georgia)
ABSTRACT Managing foreign payments using separate conduits for messaging and payments. An originating depository financial institution can create an F3X message designating a fixed amount of foreign currency to be credited to, or debited from, a receiving depository financial institution. The originating depository financial institution transmits the F3X message to a domestic gateway operator via an ACH network. The domestic gateway operator then forwards the F3X message to a foreign gateway operator. Separately, the originating depository financial institution transmits a payment to the foreign gateway operator either directly or via a correspondent financial institution. The foreign gateway operator matches the payment to the F3X message and transmits the payment to the receiving depository financial institution.
FILED Tuesday, December 18, 2007
APPL NO 12/002917
ART UNIT 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/39
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 08692176 Kelly et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Michael Kelly (North Reading, Massachusetts);  Brian Tyrrell (Brookline, New Hampshire);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Kenneth Schultz (Lexington, Massachusetts);  James Wey (Arlington, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Michael Kelly (North Reading, Massachusetts);  Brian Tyrrell (Brookline, New Hampshire);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Kenneth Schultz (Lexington, Massachusetts);  James Wey (Arlington, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ABSTRACT A digital focal plane array includes an all-digital readout integrated circuit in combination with a detector array. The readout circuit includes unit cell electronics, orthogonal transfer structures, and data handling structures. The unit cell electronics include an analog to digital converter. Orthogonal transfer structures enable the orthogonal transfer of data among the unit cells. Data handling structures may be configured to operate the digital focal plane array as a data encryptor/decipherer. Data encrypted and deciphered by the digital focal plane array need not be image data.
FILED Friday, November 18, 2011
APPL NO 13/299995
ART UNIT 2878 — Optics
CURRENT CPC
Radiant energy
250/208.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08691563 Pushko et al.
FUNDED BY
APPLICANT(S) Peter Pushko (Frederick, Maryland);  Igor Lukashevich (Cockeysville, Maryland)
ASSIGNEE(S) Medigen, Inc. (Frederick, Maryland)
INVENTOR(S) Peter Pushko (Frederick, Maryland);  Igor Lukashevich (Cockeysville, Maryland)
ABSTRACT Described herein are iDNA vectors and vaccines and methods for using the same. The iDNA generates live attenuated vaccines in eukaryotic cells in vitro or in vivo for pathogenic RNA viruses, particularly yellow fever virus and Venezuelan equine encephalitis virus. When iDNA is injected into the vaccine recipient, RNA of live attenuated virus is generated by in vivo transcription in the recipient's tissues. This initiates production of progeny attenuated viruses in the tissues of the vaccine recipient, as well as elicitation of an effective immune response protecting against wild-type, non-attenuated virus.
FILED Friday, July 17, 2009
APPL NO 13/054372
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08692529 Wyatt
FUNDED BY
APPLICANT(S) Michael A. Wyatt (Clearwater, Florida)
ASSIGNEE(S) Exelis, Inc. (McLean, Virginia)
INVENTOR(S) Michael A. Wyatt (Clearwater, Florida)
ABSTRACT A low dropout (LDO) voltage regulator includes a scaling amplifier for receiving a bandgap voltage, Vbg, and outputting a scaled Vbg. A reference MOSFET device is included for reducing the scaled Vbg by a first voltage Vgs formed across gate and source nodes of the reference MOSFET device. This forms a reduced level of the scaled Vbg. An RC network filters the reduced level of the scaled Vbg and outputs a filtered voltage. An output buffer is included for receiving and increasing the filtered voltage by a second voltage Vgs in order to recover the scaled Vbg. The scaled Vbg is used as the desired regulated voltage output. The second voltage Vgs, which is produced by the output buffer, is equal to the first voltage Vgs, which is produced by the reference MOSFET device.
FILED Monday, September 19, 2011
APPL NO 13/236012
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Power supply or regulation systems
323/274
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08694963 Hinchey et al.
FUNDED BY
APPLICANT(S) Michael G. Hinchey (Bowie, Maryland);  James L. Rash (Davidsonville, Maryland);  Joaquin Pena (Sevilla, Spain)
ASSIGNEE(S) The United States as represented by the Administrator of the National Aeronautics Space Administration (Washington, District of Columbia)
INVENTOR(S) Michael G. Hinchey (Bowie, Maryland);  James L. Rash (Davidsonville, Maryland);  Joaquin Pena (Sevilla, Spain)
ABSTRACT Systems, methods and apparatus are provided through which an evolutionary system is managed and viewed as a software product line. In some embodiments, the core architecture is a relatively unchanging part of the system, and each version of the system is viewed as a product from the product line. Each software product is generated from the core architecture with some agent-based additions. The result may be a multi-agent system software product line.
FILED Tuesday, November 29, 2011
APPL NO 13/305932
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/122
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 08, 2014.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140408.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital