FedInvent™ Patents
Patent Details for Tuesday, May 06, 2014
This page was updated on Monday, March 27, 2023 at 03:59 AM GMT
Department of Health and Human Services (HHS)
| US 08713948 | Larson et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Dale Larson (Waban, Massachusetts); Jeffrey Ruberti (Lexington, Massachusetts); John Slusarz (Hopedale, Massachusetts); Trevor Ehret (Syracuse, New York); Nicholas Goulas (Tewksbury, Massachusetts); Erin Rush (Middletown, Connecticut) |
| ABSTRACT | A drilling system including a motor that produces a sonic, linear oscillatory motion is provided for removing a frozen biological sample from a stored frozen specimen and methods of use thereof without thawing the remainder of the specimen. The stator and slider assembly is operated by a servo controller which can communicate and be programmed through a port of a PC equipped with software. |
| FILED | Thursday, May 23, 2013 |
| APPL NO | 13/901045 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration 062/62 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715436 | Bhatia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sangeeta N. Bhatia (La Jolla, California); Giovanni Vozzi (Eboli, Italy) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sangeeta N. Bhatia (La Jolla, California); Giovanni Vozzi (Eboli, Italy) |
| ABSTRACT | The invention is a series of soft lithographic methods for the microfabrication of biopolymer scaffolds for use in tissue engineering and the development of artificial organs. The methods present a wide range of possibilities to construct two- and three-dimensional scaffolds with desired characteristics according to the final application. The methods utilize an elastomer mold which the biopolymer scaffold is cast. The methods allow for the rapid and inexpensive production of biopolymer scaffolds with limited specialized equipment and user expertise. |
| FILED | Wednesday, December 31, 2003 |
| APPL NO | 10/750293 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/77 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715575 | Shih et al. |
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| APPLICANT(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Wan Y. Shih (Bryn Mawr, Pennsylvania); Huidong Li (Richland, Washington) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wei-Heng Shih (Bryn Mawr, Pennsylvania); Wan Y. Shih (Bryn Mawr, Pennsylvania); Huidong Li (Richland, Washington) |
| ABSTRACT | This invention relates to a method of making lead-free piezoelectric ceramic films. Specifically, the invention is directed to a method for fabricating lead-free piezoelectric free standing films having enhanced piezoelectric properties. The films may be used for a number of applications including incorporation in microelectronic devices such as energy harvesting devices and sensor technologies. |
| FILED | Wednesday, June 26, 2013 |
| APPL NO | 13/927962 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/82.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715621 | Swager et al. |
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| FUNDED BY |
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| APPLICANT(S) | Timothy Manning Swager (Newton, Massachusetts); Robert Guy Griffin (Newton, Massachusetts); Olesya Haze (Cambridge, Massachusetts); Bjorn Corzilius (Cambridge, Massachusetts); Albert A. Smith (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Manning Swager (Newton, Massachusetts); Robert Guy Griffin (Newton, Massachusetts); Olesya Haze (Cambridge, Massachusetts); Bjorn Corzilius (Cambridge, Massachusetts); Albert A. Smith (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides a variety of radicals, which are useful as polarizing compounds. Exemplary radicals are represented by compounds of Structural Formulae (I), (II), (III) and (IV) as described herein. |
| FILED | Thursday, March 15, 2012 |
| APPL NO | 13/421789 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715637 | Kotenko et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sergei Kotenko (East Brunswick, New Jersey); Grant F. Gallagher (East Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Sergei Kotenko (East Brunswick, New Jersey); Grant F. Gallagher (East Brunswick, New Jersey) |
| ABSTRACT | A novel IFN-α/β independent ligand receptor system which upon engagement leads, among other things, to the establishment of an anti-viral state is disclosed. Further disclosed are three closely positioned genes on human chromosome 19 that encode distinct but highly homologous proteins, designated IFN-λ1, IFN-λ2, IFN-λ3, based, inter alia, in their ability to induce antiviral protection. Expression of these proteins is induced upon viral infection. A receptor complex utilized by all three IFN-λ proteins for signaling is also disclosed. The receptor complex is generally composed of two subunits, a novel receptor designated IFN-λR1 or CRF2-12, and a second subunit, IL-10R2 or CRF2-4, which is also a shared receptor component for the IL-10 and IL-22 receptor complexes. The gene encoding IFN-λR1 is generally widely expressed, including many different cell types and tissues. Expression of these proteins is induced by immune events, including, for example, upon viral infection. Apoptotosis may also be induced under effective conditions. |
| FILED | Tuesday, October 05, 2010 |
| APPL NO | 12/898141 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/85.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715640 | Wang et al. |
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| APPLICANT(S) | Pin Wang (Pasadena, California); Lilli Yang (Pasadena, California); David Baltimore (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Pin Wang (Pasadena, California); Lilli Yang (Pasadena, California); David Baltimore (Pasadena, California) |
| ABSTRACT | Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers. |
| FILED | Friday, January 15, 2010 |
| APPL NO | 12/688689 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715649 | Dinarello et al. |
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| APPLICANT(S) | Charles A. Dinarello (Boulder, Colorado); Eli C. Lewis (Be'er Sheva, Israel) |
| ASSIGNEE(S) | The Regents of The University of Colorado, A Body Corporate (, None) |
| INVENTOR(S) | Charles A. Dinarello (Boulder, Colorado); Eli C. Lewis (Be'er Sheva, Israel) |
| ABSTRACT | Embodiments herein illustrate methods and compositions for treating medical disorders. In certain embodiments, compositions and methods relate to reducing, inhibiting or treating graft rejection, transplant rejection or diabetes in a subject. Other embodiments herein relate to compounds including naturally occurring and synthetic mutant compositions of alpha-1 antitrypsin, wherein the alpha-1 antitrypsin has no significant serine protease inhibitor activity. |
| FILED | Friday, January 30, 2009 |
| APPL NO | 12/322201 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.640 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715665 | Janne et al. |
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| APPLICANT(S) | Pasi A. Janne (Newton, Massachusetts); Jeffrey Engelman (Chestnut Hill, Massachusetts); Lewis C. Cantley (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Dana Farber Cancer Institute (Boston, Massachusetts); Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | Pasi A. Janne (Newton, Massachusetts); Jeffrey Engelman (Chestnut Hill, Massachusetts); Lewis C. Cantley (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are methods for treating cancer that is resistant to treatment with an anti-ErbB therapeutic agent and which is associated with an activating MET gene mutation or a MET gene amplification. The methods involve administering to a subject a combination of an anti-ErbB therapeutic and an anti-MET therapeutic. Also provided are methods for reducing ErbB mediated signaling or PI3 kinase mediated signaling in a cancer cell. |
| FILED | Friday, April 11, 2008 |
| APPL NO | 12/450826 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/143.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715675 | Schnitzer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jan E. Schnitzer (Encinitas, California); Philip Oh (San Diego, California) |
| ASSIGNEE(S) | Jan E. Schnitzer (San Diego, California) |
| INVENTOR(S) | Jan E. Schnitzer (Encinitas, California); Philip Oh (San Diego, California) |
| ABSTRACT | Methods of delivering an agent in a tissue-specific manner, by targeting annexin A1, a derivative of annexin A1, or a binding partner of annexin A1, are described. The methods can be used for detecting, imaging and/or treating neoplasia, angiogenesis or neovasculature, as well as for diagnostics and methods of assessing treatment efficacy. Antibodies to annexin A1 are also described, as are methods screening for agents altering annexin A1 activity. |
| FILED | Friday, April 23, 2010 |
| APPL NO | 12/766062 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/178.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715678 | Cosgrove et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael S. Cosgrove (Syracuse, New York); Anamika Patel (Syracuse, New York) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Michael S. Cosgrove (Syracuse, New York); Anamika Patel (Syracuse, New York) |
| ABSTRACT | Disclosed in this specification is a method for inhibiting the formation of vertebrate SET1 family core complexes. A guanidinium-containing molecule is used to competitively inhibit the binding of the N-SET region of a SET1 protein to WDR5, thus inhibiting the formation of the SET1 family core complex. The guanidinium-containing molecule may be, for example, an arginine-containing peptide. |
| FILED | Thursday, March 08, 2012 |
| APPL NO | 13/415474 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715686 | Kwong et al. |
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| APPLICANT(S) | Peter Kwong (Washington, District of Columbia); John Mascola (Rockville, Maryland); Gary Nabel (Washington, District of Columbia); Richard Wyatt (Rockville, Maryland); Barna Dey (Germantown, Maryland); Ling Xu (Potomac, Maryland); Tongqing Zhou (Boyds, Maryland); Joseph Sodroski (Boston, Massachusetts); Wen Yuan (Brighton, Massachusetts); Shi-Hua Xiang (Boston, Massachusetts) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Dana-Faber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); John Mascola (Rockville, Maryland); Gary Nabel (Washington, District of Columbia); Richard Wyatt (Rockville, Maryland); Barna Dey (Germantown, Maryland); Ling Xu (Potomac, Maryland); Tongqing Zhou (Boyds, Maryland); Joseph Sodroski (Boston, Massachusetts); Wen Yuan (Brighton, Massachusetts); Shi-Hua Xiang (Boston, Massachusetts) |
| ABSTRACT | Isolated immunogens including a HIV-1 gp120 polypeptide or immunogenic fragment thereof stabilized in a CD4 bound confirmation by crosslinked cysteines, and methods of their use are disclosed. The immunogens are useful, for example, for generating an immune response to HIV-1 gp120 in a subject. |
| FILED | Tuesday, August 14, 2012 |
| APPL NO | 13/585700 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/188.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715689 | Kinney et al. |
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| APPLICANT(S) | Claire Y. H. Kinney (Fort Collins, Colorado); Eric Thomas Beck (Whitefish Bay, Wisconsin); Richard M. Kinney (Fort Collins, Colorado) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Atlanta, Georgia) |
| INVENTOR(S) | Claire Y. H. Kinney (Fort Collins, Colorado); Eric Thomas Beck (Whitefish Bay, Wisconsin); Richard M. Kinney (Fort Collins, Colorado) |
| ABSTRACT | The disclosure provides chimeric West Nile/Dengue viruses comprising non-coding regions, non-structural proteins, and a C protein from a West Nile virus and prM and E proteins from a Dengue virus. Also disclosed are methods of using the chimeric viruses in diagnosis of Dengue viral infection, assessment of candidate Dengue virus vaccine efficacy, and production of Dengue prM and E proteins. |
| FILED | Monday, April 27, 2009 |
| APPL NO | 12/990322 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/202.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715736 | Sachdeva et al. |
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| APPLICANT(S) | Mandip Singh Sachdeva (Tallahassee, Florida); Ram Patlolla (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida Agricultural and Mechanical University (Tallahassee, Florida) |
| INVENTOR(S) | Mandip Singh Sachdeva (Tallahassee, Florida); Ram Patlolla (Tallahassee, Florida) |
| ABSTRACT | Methods and formulations for treating a condition of the skin by delivering therapeutic formulations to the skin that translocates active substances across the stratum corneum barrier to a targeted skin tissue. The methods and formulations comprise active substances encapsulated within surface modified nanostructured lipid carrier nanoparticles. |
| FILED | Thursday, April 30, 2009 |
| APPL NO | 12/433344 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/489 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715740 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Xiaoqin Wang (Winchester, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Xiaoqin Wang (Winchester, Massachusetts); David L. Kaplan (Concord, Massachusetts) |
| ABSTRACT | The present invention provides for methods of preparing silk nanoparticles and microparticles, methods of encapsulating an active agent into the silk nano- and microparticles and compositions comprising these silk particles. |
| FILED | Wednesday, September 29, 2010 |
| APPL NO | 13/496227 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/499 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715743 | Sutkowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | Natalie Sutkowski (Charleston, South Carolina); Semyon Rubinchik (Vernon Hills, Illinois) |
| ASSIGNEE(S) | MUSC Foundation for Research Development (Charleston, South Carolina) |
| INVENTOR(S) | Natalie Sutkowski (Charleston, South Carolina); Semyon Rubinchik (Vernon Hills, Illinois) |
| ABSTRACT | The present invention provides for methods of producing human monoclonal antibodies against a wide variety of antigens including bacterial and viral antigens, as well as tumor antigens, and various autoantigens. Also provided are the antibodies themselves, nucleic acids encoding such antibodies, cells producing such antibodies, and methods of using such antibodies for diagnostic assays and passive immunity against disease states such as infection and cancer. |
| FILED | Monday, August 04, 2008 |
| APPL NO | 12/671936 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/577 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715926 | Duerksen-Hughes et al. |
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| APPLICANT(S) | Penelope J. Duerksen-Hughes (Redlands, California); Maria Filippova (Riverside, California); Valeri Filippov (Riverside, California) |
| ASSIGNEE(S) | Loma Linda University (Loma Linda, California) |
| INVENTOR(S) | Penelope J. Duerksen-Hughes (Redlands, California); Maria Filippova (Riverside, California); Valeri Filippov (Riverside, California) |
| ABSTRACT | A method of detecting the presence of specific human papilloma virus and host cell biomarkers associated with head and neck tumors in biological samples, like saliva, blood or biopsy tissue, obtained from a subject. |
| FILED | Tuesday, November 24, 2009 |
| APPL NO | 13/130934 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715927 | Lloyd et al. |
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| APPLICANT(S) | R. Stephen Lloyd (Portland, Oregon); Irina G. Minko (Portland, Oregon); Amanda K. McCullough (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | R. Stephen Lloyd (Portland, Oregon); Irina G. Minko (Portland, Oregon); Amanda K. McCullough (Portland, Oregon) |
| ABSTRACT | Disclosed herein is the identification of human DNA polymerase κ (pol κ) as the polymerase that mediates repair of DNA containing interstrand cros slinks (ICLs). The mechanism of action of a number of chemotherapeutic and antimicrobial agents is the induction of ICLs. Thus, provided herein is a method of enhancing the efficacy of a chemotherapeutic or antimicrobial agent in a subject, including selecting a subject in need of treatment with an ICL -inducing agent and administering to the subject an ICL-inducing agent and a therapeutically effective amount of an inhibitor of pol κ. Also provided is a composition for treating a hyperproliferative disease, an autoimmune disease or an infectious disease, comprising an ICL-inducing agent and an amount of an inhibitor of pol κ sufficient to enhance the efficacy of the ICL-inducing agent. Further provided is a method of identifying a DNA polymerase inhibitor. |
| FILED | Wednesday, April 22, 2009 |
| APPL NO | 13/131936 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715928 | Libutti et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steven K. Libutti (North Potomac, Maryland); Mei He (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Steven K. Libutti (North Potomac, Maryland); Mei He (Rockville, Maryland) |
| ABSTRACT | A gene profiling signature for diagnosis and prognosis of cancer patients is disclosed herein. In one embodiment, the gene signature includes 32 or 79 cancer survival factor-associated genes. Thus, provided herein is a method of determining the prognosis of a subject with a tumor by detecting expression of five of more cancer survival factor-associated genes in a tumor sample and comparing expression of the five or more cancer survival factor-associated genes in the tumor sample to a control. In some examples, an increase in expression of ABCF1, CORO1C, DPP3, PREB, UBE3A, and PTDSS1 in a tumor sample compared to a control sample indicates poor prognosis. Also provided is a method of treating a patient diagnosed with cancer by administering a therapeutically effective amount of an agent that alters expression or activity of one or more of the disclosed cancer survival factor-associated genes. Further provided are arrays including probes or antibodies specific for a plurality of cancer survival factor-associated genes or proteins. |
| FILED | Friday, February 12, 2010 |
| APPL NO | 13/148851 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715934 | Diehl et al. |
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| FUNDED BY |
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| APPLICANT(S) | Frank Diehl (Schortens, Germany); Kenneth W. Kinzler (Bel Air, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Frank Diehl (Schortens, Germany); Kenneth W. Kinzler (Bel Air, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ABSTRACT | Modulation of the viscosity of the oil phase of a microemulsion used for amplification of DNA on a bead increases the homogeneity of product beads and the amount of amplified DNA per bead. Moreover the number of separate microemulsion populations that can be formed in parallel is increased using multi-well plates and mixer mill disruptor machines designed to lyse biological samples. |
| FILED | Tuesday, June 19, 2007 |
| APPL NO | 12/305825 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715940 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Nanuet, New York) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Nanuet, New York) |
| ABSTRACT | The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses, entirely from cloned cDNAs and in the absence of helper virus. |
| FILED | Thursday, October 04, 2001 |
| APPL NO | 09/971372 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715951 | Parhami-Seren et al. |
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| FUNDED BY |
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| APPLICANT(S) | Behnaz Parhami-Seren (So. Burlington, Vermont); Kenneth G. Mann (Grand Isle, Vermont); David N. Fass (Rochester, Minnesota) |
| ASSIGNEE(S) | The University of Vermont and State Agriculture College (Burlington, Vermont) |
| INVENTOR(S) | Behnaz Parhami-Seren (So. Burlington, Vermont); Kenneth G. Mann (Grand Isle, Vermont); David N. Fass (Rochester, Minnesota) |
| ABSTRACT | Disclosed are antibodies that selectively bind to blood coagulation factor FVIII, and highly sensitive immunological assays comprising these antibodies. Preferred assays can detect FVIII at about 3500-fold below the normal physiological levels, and have a wide array of applications including accurate monitoring of FVIII concentration in pharmaceutical products for treatment of blood coagulation disorders, and determination of FVIII levels in plasma of human patients, including those with blood coagulation disorders such as hemophilia. |
| FILED | Wednesday, July 18, 2012 |
| APPL NO | 13/552246 |
| ART UNIT | 1678 — Organic Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715964 | Felber et al. |
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| FUNDED BY |
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| APPLICANT(S) | Barbara K. Felber (Rockville, Maryland); George N. Pavlakis (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Barbara K. Felber (Rockville, Maryland); George N. Pavlakis (Rockville, Maryland) |
| ABSTRACT | The present invention provides methods of improving the levels and stability of expression of interleukin-12 family cytokine polypeptides by expressing the alpha and beta subunits of the polypeptides at their determined relative molar ratios that increase the levels and stability of expression of the heterodimer, e.g., in comparison to heterodimer expressed at an equimolar ratio. |
| FILED | Monday, May 11, 2009 |
| APPL NO | 12/992077 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/70.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715983 | Detamore et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael Detamore (Lawrence, Kansas); Stevin H. Gehrke (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Michael Detamore (Lawrence, Kansas); Stevin H. Gehrke (Lawrence, Kansas) |
| ABSTRACT | The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living cells, such as chondrocytes, encapsulated therein. In a preferred aspect, the physically cross-linked polymer is selected from the group consisting of thermally gelling polysaccharides and proteins, such as agarose or gelatin, and the chemically cross-linked or physically entangled polymer is synthesized from a water-soluble vinyl monomer, either as a homopolymer or copolymer, such as polyethylene glycol diacrylate (“PEG-DA”) and 2-hydroxyethyl methacrylate (“HEMA”). |
| FILED | Wednesday, September 05, 2012 |
| APPL NO | 13/603611 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/178 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716014 | Green et al. |
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| FUNDED BY |
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| APPLICANT(S) | Maurice Green (Wildwood, Missouri); Paul M. Loewenstein (Sain Louis, Missouri) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
| INVENTOR(S) | Maurice Green (Wildwood, Missouri); Paul M. Loewenstein (Sain Louis, Missouri) |
| ABSTRACT | The present invention relates to an improved cancer therapy comprising co-administration with the E1A 1-80 transcription-repression domain activity. In addition, E1A 1-80 can act as a monotherapy against cancers that express elevated HER2/Neu or in combination with anti-HER2/Neu, chemo- or radiotherapeutic treatments. |
| FILED | Wednesday, July 18, 2012 |
| APPL NO | 13/552407 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716015 | Pollack et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael G. Pollack (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina); Allen E. Eckhardt (Durham, North Carolina) |
| ASSIGNEE(S) | Advanced Liquid Logic, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Michael G. Pollack (Durham, North Carolina); Vamsee K. Pamula (Durham, North Carolina); Allen E. Eckhardt (Durham, North Carolina) |
| ABSTRACT | A method of inoculating a culture medium including providing a droplet including a single cell type on a droplet actuator and inoculating a culture medium with the droplet. A method of providing a metabolically useful substance to a cell culture, including providing a droplet actuator including a cell culture droplet loaded thereon, the sample droplet including cells and a cell culture medium, and a second droplet comprising a metabolically useful substance. The method also includes conducting one or more droplet operations to combine the cell culture droplet with the second droplet on the droplet actuator. Related methods, droplet actuators, and systems are also provided. |
| FILED | Monday, December 15, 2008 |
| APPL NO | 12/334575 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716017 | Parsons |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xuejun Huang Parsons (San Diego, California) |
| ASSIGNEE(S) | San Diego Regenerative Medicine Institute (San Diego, California) |
| INVENTOR(S) | Xuejun Huang Parsons (San Diego, California) |
| ABSTRACT | Pluripotent human embryonic stem cells (hESCs) hold great potential for restoring tissue and organ function, which has been hindered by inefficiency and instability of generating desired cell types through multi-lineage differentiation. This instant invention is based on the discovery that pluripotent hESCs maintained under defined culture conditions can be uniformly converted into a specific lineage by small molecule induction. Retinoic acid induces specification of neuroectoderm direct from the pluripotent state of hESCs and triggers progression to neuronal progenitors and neurons efficiently. Similarly, nicotinamide induces specification of cardiomesoderm direct from the pluripotent state of hESCs and triggers progression to cardiac precursors and cardiomyocytes efficiently. This technology provides a large supply of clinically-suitable human neuronal or cardiac therapeutic products for CNS or myocardium repair. This invention enables well-controlled efficient induction of pluripotent hESCs exclusively to a specific clinically-relevant lineage for tissue and organ engineering and regeneration, cell-based therapy, and drug discovery. |
| FILED | Tuesday, November 29, 2011 |
| APPL NO | 13/306114 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716021 | Aladjem et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mirit I. Aladjem (Potomac, Maryland); Cindy Tseng (Sandy Spring, Maryland); Haiqing Fu (Rockville, Maryland); Lixin Wang (Charlottesville, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Mirit I. Aladjem (Potomac, Maryland); Cindy Tseng (Sandy Spring, Maryland); Haiqing Fu (Rockville, Maryland); Lixin Wang (Charlottesville, Virginia) |
| ABSTRACT | Regulatory elements, specifically replicators and transgene constructs containing replicator nucleic acid sequences, are disclosed herein. Methods of using replicators and transgene constructs including replicators to inhibit, delay, or prevent gene silencing are also disclosed herein. |
| FILED | Thursday, September 07, 2006 |
| APPL NO | 12/066076 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/455 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716216 | Engelman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert W. Engelman (Tampa, Florida); William R. Gower (Seffner, Florida); Paul R. Sanberg (Spring Hill, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Robert W. Engelman (Tampa, Florida); William R. Gower (Seffner, Florida); Paul R. Sanberg (Spring Hill, Florida) |
| ABSTRACT | A composition of an immunosuppressant protein (HISP) which is achieved by the steps of obtaining supernatant from hNT neuronal cells; exposing the supernatant to preparative polyacrylamide gel; placing the active isoelectric fraction on a Blue Sepharose column to bind albumin; and collecting the free fraction containing the concentrated, isolated HISP. The HISP is anionic, has a molecular weight of 40-100 kDa, an isoelectric point of about 4.8 and is obtained from the supernatant of hNT cells. HISP can suppress proliferation of responder peripheral blood mononuclear cells in allogeneic mixed lymphocyte cultures; HISP can suppress T-cell proliferation and IL-2 production in response to phorbol 12-myristate 13-acetate (PMA), ionomycin and concanavalin-A. HISP does not act through the T-cell receptor-CD3 complex or via altered accessory signal cells. |
| FILED | Friday, May 09, 2008 |
| APPL NO | 12/118675 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716220 | Tezapsidis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nikolaos Tezapsidis (West Orange, New Jersey); Steven J. Greco (Carlstadt, New Jersey); Mark Smith (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikolaos Tezapsidis (West Orange, New Jersey); Steven J. Greco (Carlstadt, New Jersey); Mark Smith (Cleveland, Ohio) |
| ABSTRACT | The present disclosure provides compositions containing a leptin product and methods of clinical therapy and diagnostic methods for progressive cognitive disorders. According to one aspect, the described invention provides a method for treating a progressive cognitive disorder. According to another aspect, the described invention provides a method for improving resilience of cognitive function in a subject in need thereof. According to another aspect, the described invention provides a method for identifying an effective therapeutic agent for treating a progressive cognitive dysfunction disease or disorder that results from at least one of accumulation of Aβ, hyperphosphorylation of tau, or accumulation of neurofibrillary tangles. |
| FILED | Wednesday, November 04, 2009 |
| APPL NO | 12/612613 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/5.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716223 | Cunningham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Timothy J. Cunningham (Fort Washington, Pennsylvania); Lihua Yao (Wynnewood, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Timothy J. Cunningham (Fort Washington, Pennsylvania); Lihua Yao (Wynnewood, Pennsylvania) |
| ABSTRACT | A synthetic peptide sequence demonstrating neuroprotective and anti-inflammatory functions is disclosed. Methods of use for the synthetic peptide are also provided. |
| FILED | Tuesday, May 05, 2009 |
| APPL NO | 12/436066 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/8.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716229 | Stankovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Konstantina Stankovic (Boston, Massachusetts); Michael McKenna (Southborough, Massachusetts); Shyan-Yuan Kao (Needham, Massachusetts); Albert Edge (Brookline, Massachusetts) |
| ABSTRACT | Methods for treating neurodegeneration, e.g., sensorineural hearing loss, or a demyelinating disease, using bisphosphonates, ERK kinase inhibitors, and osteoprotegerin (OPG) proteins or nucleic acids. |
| FILED | Thursday, November 08, 2012 |
| APPL NO | 13/672535 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716232 | Feghali-Bostwick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carol A. Feghali-Bostwick (Pittsburgh, Pennsylvania); Yukie Yamaguchi (Kanagawa, Japan) |
| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Carol A. Feghali-Bostwick (Pittsburgh, Pennsylvania); Yukie Yamaguchi (Kanagawa, Japan) |
| ABSTRACT | C-terminal endostatin polypeptides are disclosed herein. Polynucleotides encoding these polypeptide, host cells transformed with the polynucleotides, and methods of using these polypeptides and polynucleotides are disclosed. Uses of these polypeptide, polynucleotides and expression vectors include the treatment of fibrosis in a subject. Thus, methods are provided for treating fibrosis, including fibrosis of the skin and/or the lung. |
| FILED | Wednesday, July 10, 2013 |
| APPL NO | 13/939058 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/18.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716233 | Aster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jon C. Aster (Lexington, Massachusetts); Stephen C. Blacklow (Cambridge, Massachusetts); A. Thomas Look (North Reading, Massachusetts); Adolfo A. Ferrando (New York, New York); Andrew P. Weng (Vancouver, Canada) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Jon C. Aster (Lexington, Massachusetts); Stephen C. Blacklow (Cambridge, Massachusetts); A. Thomas Look (North Reading, Massachusetts); Adolfo A. Ferrando (New York, New York); Andrew P. Weng (Vancouver, Canada) |
| ABSTRACT | The present invention is based upon the identification of regions within the NOTCH-1 receptor that, when mutated, lead to increase receptor signaling. The mutations are associated with uncontrolled cellular growth and this growth may be arrested using agents that interfere with NOTCH-1 activity, such as inhibitors of gamma-secretase. Assays for the NOTCH-1 mutations may be used diagnostically or as part of a treatment regimen for cancer patients. |
| FILED | Friday, May 22, 2009 |
| APPL NO | 12/453833 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716235 | Pollard |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Jeffrey W. Pollard (New York, New York) |
| ABSTRACT | Methods and compositions are provided for inhibiting metastasis of a tumor in a subject, or of inhibiting progression of a primary tumor in a subject which requires macrophages for progression. |
| FILED | Wednesday, April 10, 2013 |
| APPL NO | 13/860109 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716237 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jian-Dong Li (Pittsford, New York); Jae Hyang Lim (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Jian-Dong Li (Pittsford, New York); Jae Hyang Lim (Rochester, New York) |
| ABSTRACT | The present invention relates to a method for treatment or prevention of a hemorrhagic condition in a patient by administering plasminogen activator inhibitor-1 (“PAI-1”) and/or an inhibitor of deubiquitinating enzyme CYLD (“CYLD”) to a patient. Pharmaceutical compositions that include one or both of PAI-1 and an inhibitor of CYLD are also disclosed. |
| FILED | Tuesday, July 22, 2008 |
| APPL NO | 12/670778 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/20.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716243 | Zheng |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jie Zheng (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Childen's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Jie Zheng (Memphis, Tennessee) |
| ABSTRACT | Compositions and methods related to Wnt signaling regulation by Dickkopf (Dkk) polypeptides and Wnt-related diseases are disclosed. For example, compounds that bind a Dkk or LRP polypeptide are disclosed. Compounds that disrupt binding of a Dkk polypeptide to an LRP polypeptide are also disclosed. Methods for using the described compounds and compositions are also disclosed. |
| FILED | Friday, May 22, 2009 |
| APPL NO | 12/454758 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716254 | Xiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rong Xiang (San Diego, California); He Zhou (San Diego, California); Ralph A. Reisfeld (LaJolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Rong Xiang (San Diego, California); He Zhou (San Diego, California); Ralph A. Reisfeld (LaJolla, California) |
| ABSTRACT | A DNA vaccine suitable for eliciting an immune response against cancer cells comprises a DNA construct operably encoding a cancer-associated Inhibitor of Apoptosis-family protein and an immunoactive gene product, such as a cytokine or a ligand for a natural killer cell surface receptor, in a pharmaceutically acceptable carrier. A preferred cytokine is CCL21. Preferred ligands for a natural killer cell surface receptor include human MICA, human MICB, human ULBP1, human ULBP2, and human ULBP3. The cancer-associated Inhibitor of Apoptosis (IAP)-family protein is preferably a survivin protein or livin protein. Method of inhibiting tumor growth by administering the vaccine of the invention to a mammal is also described. |
| FILED | Wednesday, March 24, 2004 |
| APPL NO | 10/807897 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/00 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 2039/53 (20130101) A61K 2039/523 (20130101) A61K 2039/55522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716283 | Goguen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jon Goguen (Holden, Massachusetts); Ning Pan (Boylston, Massachusetts); Kyungae Lee (Newton, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jon Goguen (Holden, Massachusetts); Ning Pan (Boylston, Massachusetts); Kyungae Lee (Newton, Massachusetts) |
| ABSTRACT | The invention, in some aspects, relates to compounds and compositions useful for inhibiting Type III secretion systems in pathogenic bacteria, such as Yersinia Pestis. In some aspects, the invention relates to methods for discovering inhibitors of the Type III secretion system and uses of such inhibitors in the treatment and prevention of disease. |
| FILED | Wednesday, April 01, 2009 |
| APPL NO | 12/742043 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/235.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716299 | Mohapatra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Subhra Mohapatra (Tampa, Florida); W. Jack Pledger (Odessa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Subhra Mohapatra (Tampa, Florida); W. Jack Pledger (Odessa, Florida) |
| ABSTRACT | A treatment for prostate cancer using cyclin-dependent kinase inhibitors is provided. The effects of cyclin-dependent kinase inhibitors on the survival of prostate cancer cells was examined. Roscovitine, R-roscovitine, and CGP74514A were shown to induce the apoptosis of LNCaP and LNCaP-Rf cells, both of which express wild-type p53. The cyclin-dependent kinase inhibitors of the present invention induce the mitochondria-mediated apoptosis of prostate cancer cells by a dual mechanism: p53 accumulation and XIAP depletion. |
| FILED | Tuesday, December 20, 2005 |
| APPL NO | 11/306241 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/263.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716301 | Sitkovsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michail V. Sitkovsky (Bethesda, Maryland); Akio Ohta (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Michail V. Sitkovsky (Bethesda, Maryland); Akio Ohta (Rockville, Maryland) |
| ABSTRACT | A method is provided herein to increase an immune response to an antigen. The method includes administering an agent that inhibits extracellular adenosine or inhibits adenosine receptors. Also disclosed are methods to increase the efficacy of a vaccine and to increase an immune response to a tumor antigen or immune cell-mediated tumor destruction. |
| FILED | Friday, December 02, 2011 |
| APPL NO | 13/310264 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/263.340 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716306 | Wentland |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Mark P. Wentland (Watervliet, New York) |
| ABSTRACT | A compound of formula I is disclosed. Compounds of formula I are useful as analgesics, anti-inflammatory agents, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. |
| FILED | Friday, April 05, 2013 |
| APPL NO | 13/857588 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/289 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716315 | Figg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William D. Figg (Fairfax, Virginia); Kurt Eger (Leipzig, Germany); Uwe Teubert (Hameln, Germany); Michael Weiss (Bethesda, Maryland); Michael Guetschow (Bonn, Germany); Thomas Hecker (Erfurt, Germany); Sunna Hauschildt (Leipzig, Germany) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | William D. Figg (Fairfax, Virginia); Kurt Eger (Leipzig, Germany); Uwe Teubert (Hameln, Germany); Michael Weiss (Bethesda, Maryland); Michael Guetschow (Bonn, Germany); Thomas Hecker (Erfurt, Germany); Sunna Hauschildt (Leipzig, Germany) |
| ABSTRACT | A number of thalidomide metabolites having superior anti-angiogenic properties have now been isolated and identified. In addition, thalidomide analogs that mimic the effects of the isolated and identified active thalidomide metabolites, and variations of such thalidomide analogs, have been developed. Such thalidomide analog compounds show enhanced potency in the inhibition of undesirable angiogenesis without the undesirable effects of administration of thalidomide. |
| FILED | Thursday, July 19, 2007 |
| APPL NO | 11/880404 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716321 | Hirawat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Samit Hirawat (South Plainfield, New Jersey); Langdon Miller (Lebanon, New Jersey) |
| ASSIGNEE(S) | PTC Therapeutics, Inc. (South Plainfield, New Jersey) |
| INVENTOR(S) | Samit Hirawat (South Plainfield, New Jersey); Langdon Miller (Lebanon, New Jersey) |
| ABSTRACT | The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases associated with nonsense mutations. In particular, the invention relates to specific doses and dosing regimens for the use of 3-[5-(2-fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid in mammals having diseases associated with nonsense mutations. |
| FILED | Thursday, April 06, 2006 |
| APPL NO | 11/918114 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/364 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716343 | Mayo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kevin H. Mayo (Minneapolis, Minnesota); Thomas R. Hoye (St. Paul, Minnesota); Xuemei Chen (Voorheesville, New York) |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| INVENTOR(S) | Kevin H. Mayo (Minneapolis, Minnesota); Thomas R. Hoye (St. Paul, Minnesota); Xuemei Chen (Voorheesville, New York) |
| ABSTRACT | A class of topomimetic calixarene-based peptide mimetics is described. Calixarene-based peptide mimetics have various biological activities such as, for example, bactericidal activity, antiangiogenic activity, and/or antitumor activity. Methods of use and methods of designing calixarene-based peptide mimetics are described. |
| FILED | Tuesday, April 24, 2012 |
| APPL NO | 13/454525 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/569 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716344 | Mazitschek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ralph Mazitschek (Belmont, Massachusetts); James Elliot Bradner (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Ralph Mazitschek (Belmont, Massachusetts); James Elliot Bradner (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to compounds of the following formula wherein R3 is a fluorescent tag. Another aspect of the invention provides an assay for determining the inhibitory effect of a test compound on an HDAC protein comprising: incubating the HDAC protein with a substrate of the above formula in the presence of a test compound; and determining the activity of the HDAC protein. |
| FILED | Wednesday, August 11, 2010 |
| APPL NO | 13/389814 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 239/42 (20130101) C07D 401/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716422 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xianghui Liu (Metairie, Louisiana); Jingtao Zhang (Lansdale, Pennsylvania); David M. Lynn (Middleton, Wisconsin) |
| ABSTRACT | Materials and Methods for the generation of polyelectrolyte multilayers that can erode to release cationic components. The multilayers comprise layers that contain one or more cations and one or more charge-dynamic anionic polymers. Charge-dynamic anionic polymers contain side chains having removable functional groups. Removal of the functional groups results in a change in the net change in the charge of the polymer which can disrupt interactions between cations and the anionic polymers and facilitate release of cations. |
| FILED | Tuesday, October 23, 2012 |
| APPL NO | 13/658446 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Synthetic resins or natural rubbers 526/304 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716437 | Goldstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven A. Goldstein (Chicago, Illinois); Zoltan Takacs (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven A. Goldstein (Chicago, Illinois); Zoltan Takacs (Chicago, Illinois) |
| ABSTRACT | The disclosure relates to a method and system of screening for ligands which specifically bind to receptors. The method comprises expressing at least one receptor. The at least one receptor is contacted with a sample comprising at least one ligand. Whether the ligand selectively binds to the receptor is determined. |
| FILED | Friday, December 05, 2008 |
| APPL NO | 12/746410 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/324 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716438 | Agrawal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vineet Agrawal (Pittsburgh, Pennsylvania); Stephen F. Badylak (Pittsburgh, Pennsylvania); Scott Alan Johnson (Allison Park, Pennsylvania); Stephen Tottey (Swathmore, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Vineet Agrawal (Pittsburgh, Pennsylvania); Stephen F. Badylak (Pittsburgh, Pennsylvania); Scott Alan Johnson (Allison Park, Pennsylvania); Stephen Tottey (Swathmore, Pennsylvania) |
| ABSTRACT | Chemoattractant polypeptide compounds for progenitor cells and compositions and drug products comprising the compounds are provided herein. Methods for attracting progenitor cells to a location in or on a patient also are provided along with methods of growing and repairing bone. |
| FILED | Friday, October 08, 2010 |
| APPL NO | 13/500398 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716448 | Schellenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Willem Stemmer (Los Gatos, California); Chia-wei Wang (Milpitas, California); Benjamin Spink (San Carlos, California); Nathan Geething (Santa Clara, California); Wayne To (Fremont, California) |
| ASSIGNEE(S) | Amunix Operating Inc. (Mountain View, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Willem Stemmer (Los Gatos, California); Chia-wei Wang (Milpitas, California); Benjamin Spink (San Carlos, California); Nathan Geething (Santa Clara, California); Wayne To (Fremont, California) |
| ABSTRACT | The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. |
| FILED | Monday, August 02, 2010 |
| APPL NO | 12/806005 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/384 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716462 | Fire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew Fire (Washington, District of Columbia); Lia Gracey (Stanford, California); Weng-Onn Lui (Stockholm, Sweden) |
| ASSIGNEE(S) | Carnegie Institution of Washington (Washington, District of Columbia); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Andrew Fire (Washington, District of Columbia); Lia Gracey (Stanford, California); Weng-Onn Lui (Stockholm, Sweden) |
| ABSTRACT | The invention encompasses methods for improving the level and/or sustainability of expression for a target nucleic acid in a eukaryotic cell comprising: (a) modifying the target nucleic acid to introduce or to comprise signals that limit or constrain the positions of nucleosome cores, and (b) introducing the modified target nucleic acid into the eukaryotic cell, wherein the modified target nucleic acid has improved levels and/or sustainability of expression compared to original unmodified nucleic acid. |
| FILED | Monday, January 29, 2007 |
| APPL NO | 12/162243 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716472 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Benjamin L. Miller (Penfield, New York); Prakash B. Palde (Rochester, New York); Peter C. Gareiss (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Benjamin L. Miller (Penfield, New York); Prakash B. Palde (Rochester, New York); Peter C. Gareiss (Rochester, New York) |
| ABSTRACT | A tri-podal compound according to formula (I) wherein, each Z is the same and is a substituted or unsubstituted N-heteroaromatic single-, multiple-, or fused-ring; and each A is the same, and can represent a direct bond between the cyclohexane ring and Z, or a carboxamide group (—C(O)—N(H)—). Use of the compounds in combinatorial libraries, methods of making the tripodal compounds, sensor devices for detecting carbohydrate targets, and methods of using the tripodal compounds to detect carbohydrate targets in a sample are also disclosed. |
| FILED | Tuesday, October 16, 2007 |
| APPL NO | 12/526696 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/180 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716491 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Young-Tae Chang (New York, New York); Shenliang Wang (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Young-Tae Chang (New York, New York); Shenliang Wang (New York, New York) |
| ABSTRACT | The present invention is directed toward benzimidazolium dye compounds of formula (I) as follows: wherein, n is an integer from 2-10, m is an integer from 2-10, X1 and X2 are independently a halogen, Q is H or a resin, and R is (aromatic)o-(linker)p-with the linker being saturated or unsaturated C1-C5 hydrocarbons, each aromatic independently being a substituted or unsubstituted aromatic or heteroaromatic, o being 1 or 2, and p being 0 or 1. Methods of making and using these compounds are also disclosed. |
| FILED | Wednesday, July 18, 2007 |
| APPL NO | 11/779630 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/309.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08716530 — Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof
| US 08716530 | DeGrado et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William F. DeGrado (Moylan, Pennsylvania); Dahui Liu (Wynnewood, Pennsylvania); Gregory N. Tew (Amherst, Massachusetts); Michael L. Klein (Ocean City, New Jersey) |
| ASSIGNEE(S) | The Trustess of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | William F. DeGrado (Moylan, Pennsylvania); Dahui Liu (Wynnewood, Pennsylvania); Gregory N. Tew (Amherst, Massachusetts); Michael L. Klein (Ocean City, New Jersey) |
| ABSTRACT | The present invention discloses methods of use of facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, including, but not limited to, pharmaceutical uses of the polymers and oligomers as antimicrobial agents and as antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, compositions of the novel polymers and oligomers, including pharmaceutical compositions, and methods of designing and synthesizing the facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers. |
| FILED | Friday, February 03, 2012 |
| APPL NO | 13/365840 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/374 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716558 | Naleway et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John J. Naleway (Eugene, Oregon); Rachel A. Howard (Eugene, Oregon) |
| ASSIGNEE(S) | Marker Gene Technologies, Inc. (Eugene, Oregon) |
| INVENTOR(S) | John J. Naleway (Eugene, Oregon); Rachel A. Howard (Eugene, Oregon) |
| ABSTRACT | Novel pro-drugs and methods for their use to alter the growth and biological characteristics of living cells, tissues, or whole organisms are described. Such cells may include animal cells, plant cells and bacterial cells. The methods allow for selective activation of the pro-drugs at or near transformant host cells expressing a gene for an enzyme that activates the pro-drugs. Pro-drugs according to a preferred embodiment of the invention are conjugates of a bioactive compound and a chemical group that is capable of being cleaved from the bioactive compound by action of an enzyme. Methods according to this invention include, (a) introducing into targeted cells a gene encoding an enzyme and (b) administering a pro-drug, wherein the enzyme releases the pro-drug from conjugation. In a preferred embodiment of the invention, the gene encoding the enzyme is a marker gene. Methods according to a preferred embodiment of the invention include altering protein production in a plant cell such as altering glycosylation of a protein produced by the plant cell. |
| FILED | Monday, December 19, 2005 |
| APPL NO | 11/316114 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716669 | Miyaoka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert S. Miyaoka (Shoreline, Washington); Kyle Champley (Ballston Spa, New York); Lawrence MacDonald (Seattle, Washington); Thomas K. Lewellen (Port Ludlow, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Robert S. Miyaoka (Shoreline, Washington); Kyle Champley (Ballston Spa, New York); Lawrence MacDonald (Seattle, Washington); Thomas K. Lewellen (Port Ludlow, Washington) |
| ABSTRACT | A method for estimating a line or response in a positron emission tomography scanner having depth of interaction estimation capability. The method utilizes information from both detector modules detecting a coincident event. A joint probability density function combining factors accounting for intermediate Compton scattering interactions and/or a final interaction that may be either a Compton scattering interaction or photoelectric absorption is calculated. In a preferred embodiment, a Bayesian estimation scheme is used to integrate the PDF for all permutations of the measured signal pairs, and the permutation with the largest joint probability is selected to construct the estimated line of response. |
| FILED | Thursday, October 22, 2009 |
| APPL NO | 13/125966 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/363.30 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717021 | Bottomley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul A. Bottomley (Columbia, Maryland); John P. Stralka (Ellicott City, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Paul A. Bottomley (Columbia, Maryland); John P. Stralka (Ellicott City, Maryland) |
| ABSTRACT | Featured is a dosimeter device that measures SAR deposited by RF power deposition during MRI of a specimen. Such a dosimeter device includes a transducer that is configured to present a load to the MRI scanner in which the transducer is located and to provide an output representative of signals induced in the transducer. The transducer also is configured so that the presented load is substantially equivalent to another load which would be presented by the specimen during MRI of the specimen. Such a transducer also is configured so as to generate an MRI signal that is sufficient to allow the MRI scanner to adjust the RF power to a value substantially equal to that of the specimen. Also featured are methods for measuring SAR deposited by RF power deposition and apparatuses or system embodying such a dosimeter device. |
| FILED | Monday, September 08, 2008 |
| APPL NO | 12/677097 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717146 | Potyrailo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Harold Woodruff Tomlinson, Jr. (Ballston Spa, New York); William Guy Morris (Rexford, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Harold Woodruff Tomlinson, Jr. (Ballston Spa, New York); William Guy Morris (Rexford, New York) |
| ABSTRACT | An integrated interrogator for a RFID sensor is provided. The integrated interrogator comprises a digital reader in communication with the RFID sensor, an impedance reader in communication with the RFID sensor, and one or more controllers that coordinate actions of the digital reader and the impedance reader. |
| FILED | Wednesday, June 30, 2010 |
| APPL NO | 12/827611 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Communications: Electrical 340/10.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717574 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Changhuei Yang (Pasadena, California); Meng Cui (Ashburn, Virginia) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Changhuei Yang (Pasadena, California); Meng Cui (Ashburn, Virginia) |
| ABSTRACT | A detector of light transmitted through a turbid medium, comprising: one or more Digital Optical Phase Conjugation (DOPC) devices, wherein the DOPC devices include (1) a sensor for detecting input light that has been transmitted through the turbid medium and inputted on the sensor; and (2) a spatial light modulator (SLM) for outputting, in response to the input light detected by the sensor, output light that is an optical phase conjugate of the input light. |
| FILED | Wednesday, November 10, 2010 |
| APPL NO | 12/943857 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/457 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717673 | Selvin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul R. Selvin (Urbana, Illinois); Sang Hak Lee (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Paul R. Selvin (Urbana, Illinois); Sang Hak Lee (Urbana, Illinois) |
| ABSTRACT | An improved microscope stage mount with built-in fiduciary markers is used for fluorescence microscopy, and comprises: (a) an optically-transparent glass plate adapted for specimen mounting and microscope viewing and comprising a specimen mounting area; and (b) a defined and ordered, two-dimensional microscopic array of fiduciary markers, wherein the markers are polymeric pillars affixed to the plate about the specimen mounting area, wherein the markers provide a three-dimensional spatial reference for the specimen. |
| FILED | Saturday, May 28, 2011 |
| APPL NO | 13/118400 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/00 (20130101) G02B 21/34 (20130101) Original (OR) Class G02B 27/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718350 | Metzger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory Metzger (Stillwater, Minnesota); Stephen C. Schmechel (Saint Paul, Minnesota); Stephen Dankbar (Eagan, Minnesota); Jonathan Henriksen (Eden Praire, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Gregory Metzger (Stillwater, Minnesota); Stephen C. Schmechel (Saint Paul, Minnesota); Stephen Dankbar (Eagan, Minnesota); Jonathan Henriksen (Eden Praire, Minnesota) |
| ABSTRACT | A computerized method for immunohistochemistry analysis of tissue utilizes digital images of multiple adjacent tissue sections aligned within a computerized software and processed with an algorithm to quantify a two-dimensional IHC signature score for each respective slide image. In various embodiments, the IHC score is performed over several adjacent sections and further processed to produce a three-dimensional IHC quantification referred to as an IHC signature map. |
| FILED | Monday, April 09, 2012 |
| APPL NO | 13/442852 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718351 | So et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter T. c. So (Boston, Massachusetts); Bevin Engelward (Lexington, Massachusetts); Timothy Ragan (Somerville, Massachusetts); Karsten Bahlman (Cambridge, Massachusetts); Ki-Hean Kim (Belmont, Massachusetts); Lily Hsu Laiho (San Luis Obispo, California); Hayden Huang (New York, New York) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Peter T. c. So (Boston, Massachusetts); Bevin Engelward (Lexington, Massachusetts); Timothy Ragan (Somerville, Massachusetts); Karsten Bahlman (Cambridge, Massachusetts); Ki-Hean Kim (Belmont, Massachusetts); Lily Hsu Laiho (San Luis Obispo, California); Hayden Huang (New York, New York) |
| ABSTRACT | In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a microscope, determining volumetric imaging parameters, directing at least two photons into a region of interest, scanning the region of interest across a portion of the tissue, imaging a plurality of layers of the tissue in a plurality of volumes of the tissue in the region of interest, sectioning the portion of the tissue and imaging a second plurality of layers of the tissue in a second plurality of volumes of the tissue in the region of interest, detecting a fluorescence image of the tissue due to said excitation light; and processing three-dimensional data that is collected to create a three-dimensional image of the region of interest. |
| FILED | Wednesday, December 26, 2012 |
| APPL NO | 13/726931 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/133 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718363 | Desai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mukund Desai (Needham, Massachusetts); Rami Mangoubi (Newton, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Mukund Desai (Needham, Massachusetts); Rami Mangoubi (Newton, Massachusetts) |
| ABSTRACT | The invention relates to methods and systems for extracting information about a scene from a set of image data by interdependently smoothing the data, segmenting the imaged scene into coherent elements by determining edges, and estimating attributes present within the scene. These methods and systems include attribute estimation, adaptive neighborhood adjustment and preferential use of different images or imaging modalities for information extraction. |
| FILED | Friday, January 16, 2009 |
| APPL NO | 12/355567 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718743 | Izatt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph A. Izatt (Raleigh, North Carolina); Yuankai K. Tao (Durham, North Carolina); Anjul M. Davis (Little Falls, New Jersey) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Joseph A. Izatt (Raleigh, North Carolina); Yuankai K. Tao (Durham, North Carolina); Anjul M. Davis (Little Falls, New Jersey) |
| ABSTRACT | The present subject matter relates to in vivo volumetric bidirectional blood flow imaging using single-pass flow imaging spectral domain optical coherence tomography. This technique uses a modified Hilbert transform algorithm to separate moving and non-moving scatterers within a depth. The resulting reconstructed image maps the components of moving scatterers flowing into and out of the imaging axis onto opposite image halfplanes, enabling volumetric bidirectional flow mapping without manual segmentation. |
| FILED | Friday, April 24, 2009 |
| APPL NO | 12/386945 |
| ART UNIT | 3737 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery 6/407 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718755 | Gluckman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce Gluckman (Arlington, Virginia); Kristen Richardson (Fairfax, Virginia); Steven Weinstein (Washington, District of Columbia); Steven Schiff (Chevy Chase, Maryland) |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Bruce Gluckman (Arlington, Virginia); Kristen Richardson (Fairfax, Virginia); Steven Weinstein (Washington, District of Columbia); Steven Schiff (Chevy Chase, Maryland) |
| ABSTRACT | The present invention relates to methods and devices for determining the state of a neural system. In one embodiment, a plurality of stimuli to the system can be delivered to the system, and then the resulting respective responses can be analyzed to determine whether the system state is static, or whether it is undergoing dynamic changes. In another aspect of the invention, a single stimulus having a plurality of components can be administered, and the responses to each component can be contrasted and compared to determine the state of the neural system. In each case, this information can be used to predict the occurrence of neural perturbations or episodes associated with a change in the state of the neural system. |
| FILED | Monday, November 03, 2003 |
| APPL NO | 10/533421 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718951 | Mishra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bhubaneswar Mishra (New York, New York); Thomas Anantharaman (San Diego, California); Sang Lim (Millburn, New Jersey); Pierre Franquin (Westborough, Massachusetts) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Bhubaneswar Mishra (New York, New York); Thomas Anantharaman (San Diego, California); Sang Lim (Millburn, New Jersey); Pierre Franquin (Westborough, Massachusetts) |
| ABSTRACT | Methods, computer-accessible medium, and systems for generating a genome wide probe map and/or a genome wide haplotype sequence are provided. In particular, a genome wide probe map can be generated by obtaining a plurality of detectable oligonucleotide probes hybridized to at least one double stranded nucleic acid molecule cleaved with at least one restriction enzyme, and detecting the location of the detectable oligonucleotide probes. For example, genome wide haplotype sequence can be generated by analyzing at least one genome wide restriction map in conjunction with at least one genome wide probe map to determine distances between restriction sites of the genome wide restriction map(s) and locations of detectable oligonucleotide probes of the genome wide probe map(s) and defining a consensus map indicating restriction sites based on the genome wide restriction map(s) and/or locations of detectable oligonucleotide probes based on each of the genome wide probe map(s). |
| FILED | Friday, March 16, 2012 |
| APPL NO | 13/422703 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electric Digital Data Processing G06F 19/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719045 | Yoon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paula W. Yoon (Norcross, Georgia); Maren T. Scheuner (Manhattan Beach, California); Cynthia Jorgensen (Atlanta, Georgia); Muin J. Khoury (Atlanta, Georgia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia) |
| INVENTOR(S) | Paula W. Yoon (Norcross, Georgia); Maren T. Scheuner (Manhattan Beach, California); Cynthia Jorgensen (Atlanta, Georgia); Muin J. Khoury (Atlanta, Georgia) |
| ABSTRACT | Family health history information can be used to assess familial risk for common diseases and determine early detection and prevention medical strategies. Assessed familial risk of disease can then be used to determine recommendations for disease prevention and screening that are targeted to familial risk. Other factors can be included to generate personalized disease prevention recommendations. For example, personal health history information, personal health behavior information, or both can be collected and assessed to generate personalized disease prevention recommendations based on the information collected. Recommendations for disease prevention and screening based at least on familial risk can be used to provide a personalized disease prevention plan that encourages a person to make behavior changes that will reduce the risk of disease and utilize preventive health services. |
| FILED | Thursday, February 02, 2006 |
| APPL NO | 11/815445 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08713909 | Cunha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francisco J. Cunha (Avon, Connecticut); Timothy S. Snyder (Glastonbury, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Francisco J. Cunha (Avon, Connecticut); Timothy S. Snyder (Glastonbury, Connecticut) |
| ABSTRACT | A panel for use in a gas turbine engine exhaust case is disclosed. The panel has an airfoil section and a flow diverting structure adjacent a leading edge, wherein the flow diverting structure directs fluid flow into an area of the airfoil that lacks sufficient internal pressure for cooling fluid flow. |
| FILED | Wednesday, March 04, 2009 |
| APPL NO | 12/397442 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/204 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714069 | Woodall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert C. Woodall (Panama City, Florida); Gregory A. Reitmeyer (Panama City, Florida); Felipe A. Garcia (Panama City, Florida) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert C. Woodall (Panama City, Florida); Gregory A. Reitmeyer (Panama City, Florida); Felipe A. Garcia (Panama City, Florida) |
| ABSTRACT | A mine clearing system and method remotely deploys line charge from a remotely controlled two-wheeled vehicle. The wheels are connected together via a central hub shaft. Individual battery operated hub motors on each wheel communicate with a central controller and receiver mounted inside the hub shaft. The power source for the motors is contained within the hub shaft, with a battery recharge port located on the hub shaft. The line charge is wrapped around the central hub shaft. An operator uses a remote control console in communication with the receiver and central controller in the hub shaft to independently control each wheel of the vehicle. A camera can hang from a hub shaft bearing on the outside of one wheel so as to be gravitationally stabilized during vehicle movement. The camera can broadcast signals to a display at the remote control console. |
| FILED | Monday, November 05, 2012 |
| APPL NO | 13/669071 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714834 | Cowen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven J. Cowen (San Diego, California); Samuel R. Bona (La Mesa, California); Charles M. Ringer (San Diego, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven J. Cowen (San Diego, California); Samuel R. Bona (La Mesa, California); Charles M. Ringer (San Diego, California) |
| ABSTRACT | An optical coupler is used to transmit optical data across a temporary connection. A housing is configured with a transparent interface window and positioned in front of a receiving optical coupler so that optical signals pass through the transparent interface window for reception by receiving optical coupler. The receiving optical coupler has a capability of accepting alignment errors caused by aligning the housing with a mating housing in an aquatic environment. Alignment is achieved via an alignment mechanism that mechanical positions the mating optical coupling components with sufficient alignment accuracy to permit the optical coupler to receive and transmit signals. |
| FILED | Wednesday, November 30, 2011 |
| APPL NO | 13/307971 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714909 | Propheter-Hinckley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Tracy A. Propheter-Hinckley (Manchester, Connecticut) |
| ABSTRACT | A turbine engine component has an airfoil portion, which airfoil portion is bounded by a platform at one end. The platform has an as-cast open cavity bordered by at least one as-cast landing. A plate is welded to the at least one as-cast landing to cover and close the as-cast open cavity. A process for forming the turbine engine component is described. |
| FILED | Wednesday, December 22, 2010 |
| APPL NO | 12/975416 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714919 | Gibson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael E. Gibson (Greenwood, Indiana); James T. Erdmann (Indianapolis, Indiana) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Michael E. Gibson (Greenwood, Indiana); James T. Erdmann (Indianapolis, Indiana) |
| ABSTRACT | According to one embodiment, an inlet system comprises first and second incoming fluid ducts configured to be disposed outside of a vessel and to receive a first incoming fluid stream in a first direction through the first incoming fluid duct and a second fluid stream through the second incoming fluid duct in a second direction substantially parallel to the first direction. An internal fluid duct is configured to be disposed inside the vessel and to discharge internal fluid from the first and second incoming fluid streams in a third direction within the vessel substantially parallel to the first and second directions. The inlet system also comprises first and second fluid channels coupling the first and second incoming fluid ducts outside the vessel to the first internal fluid duct such that the first and second incoming fluid streams are communicated to the first internal fluid duct. |
| FILED | Friday, November 06, 2009 |
| APPL NO | 12/614161 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/184 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714927 | Jenne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Douglas C. Jenne (West Hartford, Connecticut); Matthew S. Gleiner (Vernon, Connecticut); Matthew A. Devore (Cromwell, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Douglas C. Jenne (West Hartford, Connecticut); Matthew S. Gleiner (Vernon, Connecticut); Matthew A. Devore (Cromwell, Connecticut) |
| ABSTRACT | A casting system for forming an airfoil portion of a turbine engine component is provided. The casting system includes a main body core for forming at least one internal cavity in the airfoil portion, a microcircuit skin core for forming a cooling microcircuit embedded in a wall of the airfoil portion, and a trailing edge core for forming a cooling passage in a trailing edge of the airfoil portion. The microcircuit skin core has at least one cut-back portion which is sized so as to provide said cooling microcircuit embedded in the wall with a length which allows heat-up of the trailing edge core from a gas path. |
| FILED | Tuesday, July 12, 2011 |
| APPL NO | 13/180819 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/97.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714932 | Noe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark E. Noe (Morrow, Ohio); Mark W. Marusko (Springboro, Ohio); Joshua B. Jamision (Liberty Township, Ohio); Suresh Subramanian (Mason, Ohio); Michael J. Verrilli (Loveland, Ohio); Paul Izon (Morrow, Ohio) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Mark E. Noe (Morrow, Ohio); Mark W. Marusko (Springboro, Ohio); Joshua B. Jamision (Liberty Township, Ohio); Suresh Subramanian (Mason, Ohio); Michael J. Verrilli (Loveland, Ohio); Paul Izon (Morrow, Ohio) |
| ABSTRACT | A method of making a ceramic matrix composite blade includes laying up at least one ply of the plurality of fibrous ceramic plies in a preselected arrangement to form an airfoil and dovetail preform, laying up at least one additional ply of the plurality of fibrous ceramic plies on the airfoil and dovetail preform in a second preselected arrangement to form an integral platform as part of the non-rigidized blade preform, rigidizing the blade preform to form a rigidized blade preform, and densifying the rigidized blade preform to form a ceramic matrix composite blade having an integral platform structure. A tool for making the ceramic matrix composite blade and a ceramic matrix composite blade are also disclosed. |
| FILED | Wednesday, December 31, 2008 |
| APPL NO | 12/347050 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Fluid reaction surfaces 416/241.B00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715370 | Cardenas-Valencia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andres M. Cardenas-Valencia (Tampa, Florida); Jay Dlutowski (Safety Harbor, Florida); Melynda C. Calves (Riverview, Florida); John Bumgarner (Anniston, Alabama); Larry Langebrake (St. Petersburg, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Andres M. Cardenas-Valencia (Tampa, Florida); Jay Dlutowski (Safety Harbor, Florida); Melynda C. Calves (Riverview, Florida); John Bumgarner (Anniston, Alabama); Larry Langebrake (St. Petersburg, Florida) |
| ABSTRACT | The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A method of fabricating a thin aluminum anode galvanic cell is provided, the method comprising, forming a recess in the silicon wafer, the recess having no more than three sidewalls, depositing a catalytic metal layer on a bottom surface of the recess, positioning a double-side sticky tape layer having a bottom side positioned to contact the no more than three sidewalls of the recess and positioning an aluminum foil layer to contact a top side of the double-side sticky tape layer and in overlying relation to the recess, thereby forming the galvanic cell. |
| FILED | Friday, August 30, 2013 |
| APPL NO | 14/015332 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Metal working 029/623.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715396 | Kippeny et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tadd C. Kippeny (Mount Airy, Maryland); Christopher S. Badorrek (Hagerstown, Maryland); Michael J. Bowers, II (Sykesville, Maryland); Christopher L. Rector (Lee's Summit, Missouri) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Tadd C. Kippeny (Mount Airy, Maryland); Christopher S. Badorrek (Hagerstown, Maryland); Michael J. Bowers, II (Sykesville, Maryland); Christopher L. Rector (Lee's Summit, Missouri) |
| ABSTRACT | A method for providing superadsorption of polar organic compounds using a material system is provided. The method can comprise enhancing adsorption by means of using high surface area and mass transfer rates and decreased reactivity at surface sites attractive to the polar compounds; and employing consequence management by maintaining a high rate of adsorptivity combined with high fidelity and accuracy of the material system. A modified superadsorbent material for air sampling applications comprising a superadsorbent material treated with a solution, thereby forming a treated superadsorbent material, wherein the treated superadsorbent material is substantially hydrophobic and is capable of adsorbing polar compounds. |
| FILED | Friday, August 24, 2012 |
| APPL NO | 13/593758 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation: Processes 095/143 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715653 | Turley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eva A. Turley (London, Canada); Mina J. Bissell (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eva A. Turley (London, Canada); Mina J. Bissell (Berkeley, California) |
| ABSTRACT | Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described. |
| FILED | Wednesday, November 21, 2007 |
| APPL NO | 12/515405 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715694 | Apt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Doris Apt (San Jose, California); Juha Punnonen (Belmont, California); Alice M. Brinkman (Tustin, California) |
| ASSIGNEE(S) | Altravax, Inc. (Fargo, North Dakota) |
| INVENTOR(S) | Doris Apt (San Jose, California); Juha Punnonen (Belmont, California); Alice M. Brinkman (Tustin, California) |
| ABSTRACT | The invention provides polypeptides and virus-like particles having, for example, an ability to induce an immune response to flaviviruses. The polypeptides can include C15, prM, and E polypeptide sequences. |
| FILED | Monday, April 16, 2012 |
| APPL NO | 13/448099 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/218.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715751 | Kubata et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bruno K. Kubata (Nairobi, Kenya); Samuel K. Martin (Burtonsville, Maryland); Wilbur K. Milhous (Germantown, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Bruno K. Kubata (Nairobi, Kenya); Samuel K. Martin (Burtonsville, Maryland); Wilbur K. Milhous (Germantown, Maryland) |
| ABSTRACT | The invention relates to the treatment of kintoplastid infections by administering a pharmaceutical composition containing an extract from the plant Artemisia annua. The invention also relates to isolated, semi-synthetic and synthetic artemisinins that show improved efficacy in treating kinetoplastid infections. This invention also relates to a method of treating kintoplastid infections with artelinic acid and artemisinins and where Artelinic acid is administered orally. |
| FILED | Thursday, July 16, 2009 |
| APPL NO | 12/460289 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/740 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715863 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhengcheng Zhang (Newhall, California); Phuong-Nghi Karen Lam (San Francisco, California); Mikito Nagata (Saugus, California); Hisashi Tsukamoto (Santa Clarita, California) |
| ASSIGNEE(S) | Quallion LLC (Sylmar, California) |
| INVENTOR(S) | Zhengcheng Zhang (Newhall, California); Phuong-Nghi Karen Lam (San Francisco, California); Mikito Nagata (Saugus, California); Hisashi Tsukamoto (Santa Clarita, California) |
| ABSTRACT | The battery includes an electrolyte activating one or more cathodes and one or more anodes. The electrolyte includes one or more salts in a solvent. The solvent includes one or more organic solvents and one or more silanes and/or one or more siloxanes. |
| FILED | Thursday, March 22, 2007 |
| APPL NO | 11/726632 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715867 | McNeilly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frank J. McNeilly (Portsmouth, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Frank J. McNeilly (Portsmouth, Rhode Island) |
| ABSTRACT | An anode/cathode system is disclosed for use in a Benthic microbial fuel cell. Carbon cloth forms at least a portion of the anode and is disposed on one side of a water oxygen impermeable layer, which can be weighted around a periphery thereof to hold the anode against a water-sediment interface. Carbon cloth flaps or strands can be attached to the other side of the impermeable layer to form the cathode. The anode and cathode can be divided into sections with each section having an electrical lead coupled thereto. The system is deployed onto the seafloor with the anode side in contact with the water-sediment interface. |
| FILED | Thursday, September 08, 2011 |
| APPL NO | 13/227698 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715923 | Blum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amy S Blum (Washington, District of Columbia); Banahalli R Ratna (Alexandria, Virginia); Kim Sapsford (Springfield, Virginia); Gary J Vora (Washington, District of Columbia); Carissa M Soto (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Amy S Blum (Washington, District of Columbia); Banahalli R Ratna (Alexandria, Virginia); Kim Sapsford (Springfield, Virginia); Gary J Vora (Washington, District of Columbia); Carissa M Soto (Alexandria, Virginia) |
| ABSTRACT | The present invention relates to compositions and methods for detecting analytes using detectably labeled fluorescent protein scaffolds. In certain embodiments of the invention, the scaffolds are viral particles in which the capsid viral structure provides a scaffold to attach detectably labeled fluorescent dyes and capture moieties that can be utilized to determine the presence of a desired analyte in a sample using any suitable method. The protein scaffold can contain amino acids carrying reactive groups (e.g., amines and thiols) that are spatially distributed on it with large enough separation to enable the attachment of a greater number of fluorescent label molecules without quenching. |
| FILED | Monday, August 01, 2005 |
| APPL NO | 11/574676 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715949 | Delehanty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James B Delehanty (Washington, District of Columbia); Brandy J White (Alexandria, Virginia); Baochuan Lin (Bethesda, Maryland); Frances S Ligler (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James B Delehanty (Washington, District of Columbia); Brandy J White (Alexandria, Virginia); Baochuan Lin (Bethesda, Maryland); Frances S Ligler (Potomac, Maryland) |
| ABSTRACT | A composition having: a proanthocyanidin; and a macromolecule, an assembly of macromolecules, a semi-solid, or a solid surface to which the proanthocyanidin is immobilized. |
| FILED | Thursday, August 02, 2007 |
| APPL NO | 11/832834 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.320 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715973 | Pfleger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian Frederick Pfleger (Madison, Wisconsin); Matthew Brett Begemann (Madison, Wisconsin) |
| ABSTRACT | Organic acid-tolerant microorganisms and methods of using same. The organic acid-tolerant microorganisms comprise modifications that reduce or ablate AcsA activity or AcsA homolog activity. The modifications increase tolerance of the microorganisms to such organic acids as 3-hydroxypropionic acid (3HP), acrylic acid, and propionic acid. Further modifications to the microorganisms such as increasing expression of malonyl-CoA reductase and/or acetyl-CoA carboxylase provide or increase the ability of the microorganisms to produce 3HP. Methods of generating an organic acid with the modified microorganisms are provided. Methods of using acsA or homologs thereof as counter-selectable markers include replacing acsA or homologs thereof in cells with genes of interest and selecting for the cells comprising the genes of interest with amounts of organic acids effective to inhibit growth of cells harboring acsA or the homologs. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/798835 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/141 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715988 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frances Arnold (Pasadena, California); Peter Meinhold (Pasadena, California); Matthew W. Peters (Pasadena, California); Rudi Fasan (Brea, California); Mike M. Y. Chen (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Frances Arnold (Pasadena, California); Peter Meinhold (Pasadena, California); Matthew W. Peters (Pasadena, California); Rudi Fasan (Brea, California); Mike M. Y. Chen (Pasadena, California) |
| ABSTRACT | This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable substrate with such cells. |
| FILED | Friday, April 06, 2007 |
| APPL NO | 11/697404 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716045 | Hersee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, North Carolina) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Stephen D Hersee (Albuquerque, New Mexico); Xin Wang (Albuquerque, New Mexico); Xinyu Sun (Albuquerque, New Mexico) |
| ABSTRACT | Exemplary embodiments provide semiconductor devices including high-quality (i.e., defect free) group III-N nanowires and uniform group III-N nanowire arrays as well as their scalable processes for manufacturing, where the position, orientation, cross-sectional features, length and the crystallinity of each nanowire can be precisely controlled. A pulsed growth mode can be used to fabricate the disclosed group III-N nanowires and/or nanowire arrays providing a uniform length of about 10 nm to about 1000 microns with constant cross-sectional features including an exemplary diameter of about 10-1000 nm. In addition, high-quality GaN substrate structures can be formed by coalescing the plurality of GaN nanowires and/or nanowire arrays to facilitate the fabrication of visible LEDs and lasers. Furthermore, core-shell nanowire/MQW active structures can be formed by a core-shell growth on the nonpolar sidewalls of each nanowire. |
| FILED | Friday, March 01, 2013 |
| APPL NO | 13/783219 |
| ART UNIT | 2823 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/413 (20130101) Original (OR) Class H01L 2221/1094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716254 | Xiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rong Xiang (San Diego, California); He Zhou (San Diego, California); Ralph A. Reisfeld (LaJolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Rong Xiang (San Diego, California); He Zhou (San Diego, California); Ralph A. Reisfeld (LaJolla, California) |
| ABSTRACT | A DNA vaccine suitable for eliciting an immune response against cancer cells comprises a DNA construct operably encoding a cancer-associated Inhibitor of Apoptosis-family protein and an immunoactive gene product, such as a cytokine or a ligand for a natural killer cell surface receptor, in a pharmaceutically acceptable carrier. A preferred cytokine is CCL21. Preferred ligands for a natural killer cell surface receptor include human MICA, human MICB, human ULBP1, human ULBP2, and human ULBP3. The cancer-associated Inhibitor of Apoptosis (IAP)-family protein is preferably a survivin protein or livin protein. Method of inhibiting tumor growth by administering the vaccine of the invention to a mammal is also described. |
| FILED | Wednesday, March 24, 2004 |
| APPL NO | 10/807897 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/00 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 2039/53 (20130101) A61K 2039/523 (20130101) A61K 2039/55522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716464 | Geisbert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas W. Geisbert (Albany, Texas); Amy C. H. Lee (Burnaby, Canada); Marjorie Robbins (Vancouver, Canada); Vandana Sood (Vancouver, Canada); Adam Judge (Vancouver, Canada); Lisa E. Hensley (Frederick, Maryland); Ian MacLachlan (Mission, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas W. Geisbert (Albany, Texas); Amy C. H. Lee (Burnaby, Canada); Marjorie Robbins (Vancouver, Canada); Vandana Sood (Vancouver, Canada); Adam Judge (Vancouver, Canada); Lisa E. Hensley (Frederick, Maryland); Ian MacLachlan (Mission, Canada) |
| ABSTRACT | The present invention provides compositions comprising therapeutic nucleic acids (e.g., interfering RNA such as siRNA) that target Ebola virus (EBOV) gene expression and methods of using such compositions to silence EBOV gene expression. More particularly, the invention provides unmodified and chemically modified interfering RNA which silence EBOV gene expression and methods of use thereof, e.g., for preventing or treating EBOV infections caused by one or more EBOV species such as Zaire EBOV. The invention also provides serum-stable nucleic acid-lipid particles comprising one or more interfering RNA molecules, a cationic lipid, and a non-cationic lipid, which can further comprise a conjugated lipid that inhibits aggregation of particles. Methods of silencing EBOV gene expression by administering one or more interfering RNA molecules to a mammalian subject are also provided. |
| FILED | Tuesday, July 20, 2010 |
| APPL NO | 12/840225 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716670 | Blackburn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brandon W. Blackburn (Idaho Falls, Idaho); Michael V. Hynes (Cambridge, Massachusetts); Anthony G. Galaitsis (Lexington, Massachusetts); Bernard Harris (Wayland, Massachusetts); Erik D. Johnson (Boston, Massachusetts); Bruce William Chignola (Marlborough, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Brandon W. Blackburn (Idaho Falls, Idaho); Michael V. Hynes (Cambridge, Massachusetts); Anthony G. Galaitsis (Lexington, Massachusetts); Bernard Harris (Wayland, Massachusetts); Erik D. Johnson (Boston, Massachusetts); Bruce William Chignola (Marlborough, Massachusetts) |
| ABSTRACT | Methods and apparatus for a detector system to detect gamma and neutron radiation. In one embodiment, a detector comprises a tank to hold a liquid, a plurality of tubes adjacent the tank to detect neutrons, and a plurality of photon detectors to detect Cherenkov light generated by gamma radiation in the liquid. The tank is configured to contain the liquid so that the liquid generates the Cherenkov light and moderates the neutrons. |
| FILED | Thursday, December 29, 2011 |
| APPL NO | 13/339571 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/390.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716685 | Bushmaker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Adam Wayne Bushmaker (Los Angeles, California); William T. Lotshaw (Rancho Palos Verdes, California) |
| ABSTRACT | A terahertz generating assembly generally includes a light emitting device that is configured to generate at least one pulsed light beam. A first dispersion member is positioned proximate to the light emitting device, wherein the first dispersion member is configured to facilitate a temporal dispersion of the light beam. A second dispersion member is positioned proximate to the first dispersion member and to the light emitting device, wherein the second dispersion member is configured to facilitate a spatial dispersion of the light beam. A lens is positioned proximate to each of the first and second dispersion members, wherein the lens is configured to focus the temporal and spatial dispersions to produce at least one moving spot of light. At least one waveguide is positioned proximate to the lens, wherein the waveguide is configured to apply a biased voltage to the spot of light to generate pulsed terahertz radiation. |
| FILED | Thursday, December 27, 2012 |
| APPL NO | 13/728688 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) H01S 5/0057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716798 | Fuller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nicholas C Fuller (North Hills, New York); Steve Koester (Minneapolis, Minnesota); Isaac Lauer (Mahopac, New York); Ying Zhang (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Nicholas C Fuller (North Hills, New York); Steve Koester (Minneapolis, Minnesota); Isaac Lauer (Mahopac, New York); Ying Zhang (Yorktown Heights, New York) |
| ABSTRACT | A method for fabricating recessed source and recessed drain regions of aggressively scaled CMOS devices. In this method a processing sequence of plasma etch, deposition, followed by plasma etch is used to controllably form recessed regions of the source and the drain in the channel of a thin body, much less than 40 nm, device to enable subsequent epitaxial growth of SiGe, SiC, or other materials, and a consequent increase in the device and ring oscillator performance. A Field Effect Transistor device is also provided, which includes: a buried oxide layer; a silicon layer above the buried oxide layer; an isotropically recessed source region; an isotropically recessed drain region; and a gate stack which includes a gate dielectric, a conductive material, and a spacer. |
| FILED | Thursday, May 13, 2010 |
| APPL NO | 12/779100 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/347 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717123 | Schreiber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adam W. Schreiber (Fredericksburg, Virginia); Louis F. DeChiaro, Jr. (Middletown, Delaware) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Adam W. Schreiber (Fredericksburg, Virginia); Louis F. DeChiaro, Jr. (Middletown, Delaware) |
| ABSTRACT | A coaxial mirror is provided for reflecting an electromagnetic signal. The mirror includes an outer pipe, an inner pipe, and first and second rods. The outer pipe extends between input and output ports, with closed initial and final terminals disposed at their respective ports. The inner pipe extends between a closed fore end and an open aft end. The inner pipe is coaxially disposed between the initial and final terminals within the outer pipe. The first rod, coaxially disposed within the outer pipe, extends from the input port to the fore end. The second rod, coaxially disposed within the inner pipe, extends from downstream of the fore end to the output port. Preferably, the first and second pipes are cylindrical tubes. Preferably, fluoropolymer fills the annular region between the inner and outer pipes, and fluoropolymer foam fills the inner pipe. Preferably, the first pipe has an electrically conductive inner surface, the second pipe has electrically conductive inner and outer surfaces, and the first and second rods have conductive surfaces. A first embodiment includes a conductor, coaxially disposed within the inner pipe, that extends from the fore end to the second rod. In a second embodiment, the second rod is hollow, and is preferably filled with the foam. |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/924026 |
| ART UNIT | 2843 — Printing/Measuring and Testing |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/202 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717351 | Wirtz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Matthew Wirtz (Ridgecrest, California); Frank Joseph Modlinski (Ridgecrest, California); Nathan Joseph Kielman (Ridgecrest, California); William Rodney Ditzler (Ridgecrest, California); David Daniel Schaeffer (Ridgecrest, California); An Vinh (Ridgecrest, California); Stephanie Stites (Ridgecrest, California); Patrick Robert Simpson (Ridgecrest, California); Brett Thomas Edwards (Ridgecrest, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Matthew Wirtz (Ridgecrest, California); Frank Joseph Modlinski (Ridgecrest, California); Nathan Joseph Kielman (Ridgecrest, California); William Rodney Ditzler (Ridgecrest, California); David Daniel Schaeffer (Ridgecrest, California); An Vinh (Ridgecrest, California); Stephanie Stites (Ridgecrest, California); Patrick Robert Simpson (Ridgecrest, California); Brett Thomas Edwards (Ridgecrest, California) |
| ABSTRACT | A PFI reader. |
| FILED | Wednesday, September 29, 2010 |
| APPL NO | 12/924794 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717384 | Wirtz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Matthew Wirtz (Ridgecrest, California); David Daniel Schaeffer (Ridgecrest, California); An Vinh (Ridgecrest, California); Stephanie Stites (Ridgecrest, California); Patrick Robert Simpson (Ridgecrest, California); Brett Thomas Edwards (Ridgecrest, California); Frank Joseph Modlinski (Ridgecrest, California); Nathan Joseph Kielman (Ridgecrest, California); William Rodney Ditzler (Ridgecrest, California) |
| ASSIGNEE(S) | The United State of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Matthew Wirtz (Ridgecrest, California); David Daniel Schaeffer (Ridgecrest, California); An Vinh (Ridgecrest, California); Stephanie Stites (Ridgecrest, California); Patrick Robert Simpson (Ridgecrest, California); Brett Thomas Edwards (Ridgecrest, California); Frank Joseph Modlinski (Ridgecrest, California); Nathan Joseph Kielman (Ridgecrest, California); William Rodney Ditzler (Ridgecrest, California) |
| ABSTRACT | An image file format article of manufacture for a PFI. |
| FILED | Tuesday, September 28, 2010 |
| APPL NO | 12/924801 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/629 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717551 | Baraniuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | InView Technology Corporation (Austin, Texas) |
| ASSIGNEE(S) | InView Technology Corporation (Austin, Texas) |
| INVENTOR(S) | Richard G. Baraniuk (Houston, Texas); Tyler H. Weston (Austin, Texas) |
| ABSTRACT | A system and method for searching an incident light field for atypical regions (e.g., hot spots or cool spots or spectrally distinctive regions) within the incident light field using a light modulator and a spectral sensing device. Once the atypical regions are identified, the light modulator may be used to mask the incident light field so that the spectral sensing device can make spatially-concentrated measurements of the wavelength spectrum of the atypical regions (or alternatively, the exterior of the atypical regions). Furthermore, in a compressive imaging mode, a sequence of spatial patterns may be supplied to the light modulator, and a corresponding sequence of wavelength spectra may be collected from the spectral sensing device. The wavelength spectra comprise a compressed representation of the incident light field over space and wavelength. The wavelength spectra may be used to reconstruct a multispectral (or hyperspectral) data cube. |
| FILED | Friday, September 28, 2012 |
| APPL NO | 13/631626 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/121 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717569 | Lo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yu-Hwa Lo (San Diego, California); Victor Jie Lien (San Diego, California); Chun Hao Randy Chen (Arcadia, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yu-Hwa Lo (San Diego, California); Victor Jie Lien (San Diego, California); Chun Hao Randy Chen (Arcadia, California) |
| ABSTRACT | A number of fluidic-photonic devices for allowing optical detection, systems employing such devices, and related methods of operation and fabrication of such devices are disclosed herein. In at least some embodiments, the devices can serve as flow cytometry devices and/or employ microfluidic channels. Also, in at least some embodiments, the devices are fluidic-photonic integrated circuit (FPIC) devices that employ both fluidic channels and one or more waveguides capable of receiving and/or delivering light, and that can be fabricated using polymeric materials. The fluidic-photonic devices in at least some embodiments are capable of functionality such as on-chip excitation, time-of-flight measurement, and can experience enhanced fluorescence detection sensitivity. In at least some embodiments, the devices employ detection waveguides that are joined by way of a waveguide demultiplexer. In additional embodiments, a variety of techniques can be used to process information received via the waveguides, including an iterative cross-correlation process. |
| FILED | Thursday, September 06, 2012 |
| APPL NO | 13/605925 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Optics: Measuring and testing 356/436 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717577 | Kokobun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Kokobun (Waipahu, Hawaii); Christopher E Saxer (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Daniel Kokobun (Waipahu, Hawaii); Christopher E Saxer (Chapel Hill, North Carolina) |
| ABSTRACT | The invention allows a shearography system to successfully sense ground/surface vibrations while moving at aircraft speeds and altitudes. This is done by effectively making stationary the apparent location of a coherent laser beam illuminating an area on the ground/surface, and also effectively making stationary the apparent location of the aperture of an optical receiver which acquires pairs of sequential images captured and used for shearography. A different laser is used for capturing each of the two images, and the distance between the two lasers is adjusted based on a number of operational parameters. The adjustment of the distance causes the apparent locations of the transmitter and a receiver sub-aperture to remain the same and permits the moving shearography to work. |
| FILED | Tuesday, January 24, 2012 |
| APPL NO | 13/357574 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/520 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717657 | Delfyett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter J. Delfyett (Orlando, Florida); Ibrahim T. Ozdur (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orldando, Florida) |
| INVENTOR(S) | Peter J. Delfyett (Orlando, Florida); Ibrahim T. Ozdur (Orlando, Florida) |
| ABSTRACT | An optoelectronic oscillator (OEO) is used to provide a continuous, high Q, modulated signal for a variety of purposes, including a carrier wave for communications, and radar emissions. The OEO of this invention replaces an RF filter in the conventional OEO with an interferometer, preferably a high finesse Fabry-Perot etalon as the mode selector, providing lower phase noise and higher RF frequency stability. |
| FILED | Friday, May 27, 2011 |
| APPL NO | 13/117271 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717692 | Miller |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kirk A. Miller (Dallas, Texas) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Kirk A. Miller (Dallas, Texas) |
| ABSTRACT | An optical switching system and method of selecting between one of several available in optic modules in an optical system is disclosed. In one example, the optical switching system comprises a focus cell assembly disposed in a plane, a rotatable field of view optic system having an axis, configured to rotate around the axis, the axis disposed in parallel to the plane of the focus cell, and a cam device mounted to the field of view optic system and configured to push the focus cell assembly away from the field of view optic system with each rotation of the field of view optic system. |
| FILED | Friday, December 30, 2011 |
| APPL NO | 13/340952 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/821 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717849 | Zarnetske et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael R. Zarnetske (Bristol, Rhode Island); Robert S. Janus (Hope, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael R. Zarnetske (Bristol, Rhode Island); Robert S. Janus (Hope, Rhode Island) |
| ABSTRACT | A slotted cylinder acoustic transducer assembly is provided that has a cylindrical housing shell and an electromechanical driver disposed within the shell. The driver is formed with a plurality of single crystal piezoelectric elements joined to the inner surface of the housing shell and arranged to form an electromechanical stack. Each piezoelectric element has a pair of sidewalls, wherein each sidewall provides an electrode having a predetermined polarity. Each single piezoelectric element has a tapering width between the sidewalls. The transducer assembly includes a plurality of electrically conductive members. Each conductive member is disposed between each pair of adjacent piezoelectric elements such that each electrically conductive member electrically contacts the electrodes of adjacent piezoelectric elements. |
| FILED | Friday, September 09, 2011 |
| APPL NO | 13/228680 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718111 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lin Zhu (Central, South Carolina); Yunsong Zhao (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University (Clemson, South Carolina) |
| INVENTOR(S) | Lin Zhu (Central, South Carolina); Yunsong Zhao (Clemson, South Carolina) |
| ABSTRACT | A diode laser includes a p-contact layer, a n-contact layer, and a wafer body disposed between the p-contact layer and the n-contact layer, the wafer body having a front end and a back end. The diode laser further includes a first grating comprising a plurality of grooves defined in the wafer body and extending between the front end and the back end at a first tilt angle, and a second grating comprising a plurality of grooves defined in the wafer body and extending between the front end and the back end at a second tilt angle, the second tilt angle opposite to the first tilt angle. A coupling region is defined in the wafer body by interleaving portions of the first grating and the second grating. The interleaving portions provide coherent coupling of laser beams flowing through the first grating and the second grating. |
| FILED | Wednesday, May 23, 2012 |
| APPL NO | 13/478392 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/00 (20130101) H01S 5/026 (20130101) Original (OR) Class H01S 5/0287 (20130101) H01S 5/1209 (20130101) H01S 5/1228 (20130101) H01S 5/1237 (20130101) H01S 5/18341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718185 | Giannakis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Saint Paul, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Georgios B. Giannakis (Minnetonka, Minnesota); Xiaoli Ma (Auburn Norcross, Georgia) |
| ABSTRACT | Techniques are described for carrier frequency offset (CFO) and channel estimation of orthogonal frequency division multiplexing (OFDM) transmissions over multiple-input multiple-output (MIMO) frequency-selective fading channels. A wireless transmitter forms blocks of symbols by inserting training symbols within two or more blocks of information-bearing symbols. The transmitter applies a hopping code to each of the blocks of symbols to insert a null subcarrier at a different position within each of the blocks of symbols, and a modulator outputs a wireless signal in accordance with the blocks of symbols. A receiver receives the wireless signal and estimates the CFO, and outputs a stream of estimated symbols based on the estimated CFO. |
| FILED | Tuesday, February 26, 2013 |
| APPL NO | 13/777993 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718219 | Bertozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Bertozzi (Lexington, Massachusetts); Robert J. Ledoux (Harvard, Massachusetts) |
| ASSIGNEE(S) | Passport Systems, Inc. (Billerica, Massachusetts) |
| INVENTOR(S) | William Bertozzi (Lexington, Massachusetts); Robert J. Ledoux (Harvard, Massachusetts) |
| ABSTRACT | Methods and systems for non-intrusively detecting the existence of fissile materials in a container via the measurement of energetic prompt neutrons are disclosed. The methods and systems use the unique nature of the prompt neutron energy spectrum from photo-fission arising from the emission of neutrons from almost fully accelerated fragments to unambiguously identify fissile material. The angular distribution of the prompt neutrons from photo-fission and the energy distribution correlated to neutron angle relative to the photon beam are used to distinguish odd-even from even-even nuclei undergoing photo-fission. The independence of the neutron yield curve (yield as a function of electron beam energy or photon energy) on neutron energy also is also used to distinguish photo-fission from other processes such as (γ, n). Different beam geometries are used to detect localized samples of fissile material and also fissile materials dispersed as small fragments or thin sheets over broad regions. These signals from photo-fission are unique and allow the detection of any material in the actinide region of the nuclear periodic table. |
| FILED | Friday, June 13, 2008 |
| APPL NO | 12/139050 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718421 | Morton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul A. Morton (West Friendship, Maryland); Jacob Khurgin (Baltimore, Maryland) |
| ASSIGNEE(S) | Morton Photonics (West Friendship, Maryland) |
| INVENTOR(S) | Paul A. Morton (West Friendship, Maryland); Jacob Khurgin (Baltimore, Maryland) |
| ABSTRACT | This invention provides an optical device comprising a large group of non-uniform resonators operating cumulatively as a ‘super-ring’ to provide a controllable group delay with large bandwidth. The super-ring tuning is performed by a single control. The device may include two super-rings, each includes a large number of resonators with a resonant frequencies centered around ω1 and ω2 respectively. The invention provides multiple ways to improve the delay duration, bandwidth and the tuning speed, and overcomes the issue of non-uniformity of resonance frequency for devices incorporating multiple optical resonators. |
| FILED | Thursday, March 10, 2011 |
| APPL NO | 13/044669 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718555 | Seidel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott Y. Seidel (Fairfax, Virginia); Michael R. Franceschini (Centerport, New York) |
| ASSIGNEE(S) | Powerwave Cognition, Inc. (Santa Ana, California) |
| INVENTOR(S) | Scott Y. Seidel (Fairfax, Virginia); Michael R. Franceschini (Centerport, New York) |
| ABSTRACT | Using bearer channels for wireless nodes includes initiating communication among the wireless nodes that include a node and one or more neighbor nodes. An adaptive channel operable to communicate messages between the node and the neighbor nodes is established. One or more bearer channels are selected. The one or more neighbor nodes are notified of the one or more selected bearer channels using the adaptive channel. The node and the neighbor nodes communicate over the bearer channels. |
| FILED | Friday, November 10, 2006 |
| APPL NO | 11/595542 |
| ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/41.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718753 | Chon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ki H. Chon (Worcester, Massachusetts); Jinseok Lee (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ki H. Chon (Worcester, Massachusetts); Jinseok Lee (Worcester, Massachusetts) |
| ABSTRACT | Technologies are provided herein for real-time detection of motion and noise (MN) artifacts in electrocardiogram signals recorded by electrocardiography devices. Specifically, the present disclosure provides techniques for increasing the accuracy of identifying paroxysmal atrial fibrillation (AF) rhythms, which are often measured via such devices. According to aspects of the present disclosure, a method for detecting MN artifacts in an electrocardiogram (ECG) recording includes receiving an ECG segment and decomposing the received ECG segment into a sum of intrinsic mode functions. The intrinsic mode functions associated with MN artifacts present within the ECG segment are then isolated. The method further includes determining randomness and variability characteristic values associated with the isolated intrinsic mode functions and comparing the randomness and variability characteristic values to threshold randomness and variability characteristic values. If the randomness and variability characteristic values exceed the threshold characteristic values, the ECG signal is determined to include MN artifacts. |
| FILED | Wednesday, October 12, 2011 |
| APPL NO | 13/823812 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 6/521 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718796 | Cevette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Cevette (Scottsdale, Arizona); Jan Stepanek (Scottsdale, Arizona); Anna Galea (Stow, Massachusetts) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education (Rochester, Minnesota); Research Vivonics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Michael Cevette (Scottsdale, Arizona); Jan Stepanek (Scottsdale, Arizona); Anna Galea (Stow, Massachusetts) |
| ABSTRACT | The present invention relates to systems and techniques for stimulating a user. For example, materials and methods for manipulating nystagmus and the related vestibular system with coupling of galvanic vestibular stimulation (GVS) and visual cueing are provided herein. Use of GVS within the present invention may be applied to simulation, alleviating motion sickness, and directional cueing of a user to a precise target location. |
| FILED | Thursday, March 04, 2010 |
| APPL NO | 12/660768 |
| ART UNIT | 3766 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/148 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718841 | Cherepinsky |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Igor Cherepinsky (Sandy Hook, Connecticut) |
| ASSIGNEE(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| INVENTOR(S) | Igor Cherepinsky (Sandy Hook, Connecticut) |
| ABSTRACT | A system for providing sideslip envelope protection includes a processor for obtaining values of a sideslip envelope indicative of operating conditions of the aircraft along an axis and for estimating a sideslip angle along the axis from at least one operating condition; and a comparer for comparing the sideslip angle with the sideslip envelope to generate an output value, where the processor determines a maximum yaw rate from the output value and scales the maximum yaw rate to generate a scaled yaw rate. |
| FILED | Tuesday, February 14, 2012 |
| APPL NO | 13/372863 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719317 | Crain |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Louis M. Crain (La Mesa, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Louis M. Crain (La Mesa, California) |
| ABSTRACT | Embodiments of the invention relate to converting infrared, radar, and photographic sensor data using an apparatus having a graphical user interface, a user-selection device, and an electronic processor configured to convert sensor data conversion computer program (abbreviated “computer program”) is associated with the electronic processor. A sensor standard definition file is consistent with a sensor standard (abbreviated “the standard”)and is configured for input to the computer program. The sensor standard definition file is a programmable external file defining specifies (elements used to communicate sensor data in the computer program) of the standard. The sensor standard definition file is editable and extendable to support changes in the standard. A sensor standard rules file, sensor external standard file, and sensor external data file are consistent with the standard and are operatively associated with the computer program. |
| FILED | Thursday, December 30, 2010 |
| APPL NO | 12/930910 |
| ART UNIT | 2166 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/813 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719943 | Noel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven E Noel (Dale City, Virginia); Sushil Jajodia (Oakton, Virginia); Eric B Robertson (Vienna, Virginia) |
| ASSIGNEE(S) | George Mason Intellectual Properties, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Steven E Noel (Dale City, Virginia); Sushil Jajodia (Oakton, Virginia); Eric B Robertson (Vienna, Virginia) |
| ABSTRACT | Disclosed is a system for correlating intrusion events using attack graph distances. The system includes an attack graph generator, an exploit distance calculator, an intrusion detector, an event report/exploit associator, an event graph creator, an event graph distance calculator, a correlation value calculator, and a coordinated attack analyzer. An attack graph is constructed for exploits and conditions in a network. The exploit distance calculator determines exploit distances for exploit pair(s). The intrusion detector generates event. Events are associated with exploits. Event graph distances are calculated. Correlation values are calculated for event pair(s) using event graph distances. The correlation values are analyzed using a correlation threshold to detect coordinated attacks. |
| FILED | Tuesday, May 08, 2012 |
| APPL NO | 13/466706 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Information security 726/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08713929 | McBride et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Troy O. McBride (Norwich, Vermont); Benjamin Bollinger (Windsor, Vermont) |
| ASSIGNEE(S) | Sustainx, Inc. (Seabrook, New Hampshire) |
| INVENTOR(S) | Troy O. McBride (Norwich, Vermont); Benjamin Bollinger (Windsor, Vermont) |
| ABSTRACT | The invention relates to methods and systems for the storage and recovery of energy using open-air hydraulic-pneumatic accumulator and intensifier arrangements that combine at least one accumulator and at least one intensifier in communication with a high-pressure gas storage reservoir on a gas-side of the circuits and a combination fluid motor/pump, coupled to a combination electric generator/motor on the fluid side of the circuits. |
| FILED | Tuesday, June 05, 2012 |
| APPL NO | 13/488787 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/410 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715345 | DeBoer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Charles DeBoer (Pasadena, California); Yu-Chong Tai (Pasadena, California); Mark Humayun (Glendale, California) |
| ABSTRACT | Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. The lenses can be made from silicone, fluorosilicone, and phenyl substituted silicone and be semipermeable to air. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens. |
| FILED | Wednesday, February 06, 2013 |
| APPL NO | 13/761024 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Prosthesis 623/6.130 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715718 | Moghe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Prabhas V. Moghe (Basking Ridge, New Jersey); Ram Sharma (Montville, New Jersey); Marian Pereira Guelakis (Cranford, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Prabhas V. Moghe (Basking Ridge, New Jersey); Ram Sharma (Montville, New Jersey); Marian Pereira Guelakis (Cranford, New Jersey) |
| ABSTRACT | Compositions, methods, and kits for repair and production of extracellular matrix are provided. In the broad aspect, the composition comprises a ligand of α5β1 integrin attached to a surface of a nanoparticle composed of a protein, with a proviso that the protein is not fibronectin. |
| FILED | Wednesday, July 11, 2007 |
| APPL NO | 12/373671 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/443 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715983 | Detamore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Detamore (Lawrence, Kansas); Stevin H. Gehrke (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Michael Detamore (Lawrence, Kansas); Stevin H. Gehrke (Lawrence, Kansas) |
| ABSTRACT | The present invention is directed to a hydrogel network comprised of a physically cross-linked polymer and a chemically cross-linked polymer or physically entangled copolymer containing living cells, such as chondrocytes, encapsulated therein. In a preferred aspect, the physically cross-linked polymer is selected from the group consisting of thermally gelling polysaccharides and proteins, such as agarose or gelatin, and the chemically cross-linked or physically entangled polymer is synthesized from a water-soluble vinyl monomer, either as a homopolymer or copolymer, such as polyethylene glycol diacrylate (“PEG-DA”) and 2-hydroxyethyl methacrylate (“HEMA”). |
| FILED | Wednesday, September 05, 2012 |
| APPL NO | 13/603611 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/178 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715988 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frances Arnold (Pasadena, California); Peter Meinhold (Pasadena, California); Matthew W. Peters (Pasadena, California); Rudi Fasan (Brea, California); Mike M. Y. Chen (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Frances Arnold (Pasadena, California); Peter Meinhold (Pasadena, California); Matthew W. Peters (Pasadena, California); Rudi Fasan (Brea, California); Mike M. Y. Chen (Pasadena, California) |
| ABSTRACT | This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable substrate with such cells. |
| FILED | Friday, April 06, 2007 |
| APPL NO | 11/697404 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716460 | Alfano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James R. Alfano (Lincoln, Nebraska); Alan Collmer (Ithaca, New York); Samuel W. Cartinhour (Ithaca, New York); David J. Schneider (Trumansburg, New York); Xiaoyan Tang (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas); The Board of Regents of the University of Nebraska (Lincoln, Nebraska); Cornell Research Foundation, Inc. (Ithaca, New York); The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | James R. Alfano (Lincoln, Nebraska); Alan Collmer (Ithaca, New York); Samuel W. Cartinhour (Ithaca, New York); David J. Schneider (Trumansburg, New York); Xiaoyan Tang (Manhattan, Kansas) |
| ABSTRACT | One aspect of the present invention relates to isolated nucleic acid molecules encoding avirulence proteins or polypeptides of Pseudomonas syringae pv. syringae DC 3000, or nucleic acid molecules which are complementary thereto. Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The various nucleic acid molecules and proteins of the present invention can be used to impart disease resistance to a plant, make a plant hypersusceptible to colonization by nonpathogenic bacteria, modify a metabolic pathway in a cell, cause eukaryotic cell death and treat a cancerous condition, as well as inhibit programmed cell death. |
| FILED | Wednesday, December 27, 2006 |
| APPL NO | 11/616609 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716558 | Naleway et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John J. Naleway (Eugene, Oregon); Rachel A. Howard (Eugene, Oregon) |
| ASSIGNEE(S) | Marker Gene Technologies, Inc. (Eugene, Oregon) |
| INVENTOR(S) | John J. Naleway (Eugene, Oregon); Rachel A. Howard (Eugene, Oregon) |
| ABSTRACT | Novel pro-drugs and methods for their use to alter the growth and biological characteristics of living cells, tissues, or whole organisms are described. Such cells may include animal cells, plant cells and bacterial cells. The methods allow for selective activation of the pro-drugs at or near transformant host cells expressing a gene for an enzyme that activates the pro-drugs. Pro-drugs according to a preferred embodiment of the invention are conjugates of a bioactive compound and a chemical group that is capable of being cleaved from the bioactive compound by action of an enzyme. Methods according to this invention include, (a) introducing into targeted cells a gene encoding an enzyme and (b) administering a pro-drug, wherein the enzyme releases the pro-drug from conjugation. In a preferred embodiment of the invention, the gene encoding the enzyme is a marker gene. Methods according to a preferred embodiment of the invention include altering protein production in a plant cell such as altering glycosylation of a protein produced by the plant cell. |
| FILED | Monday, December 19, 2005 |
| APPL NO | 11/316114 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716675 | Chetwani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nishant Chetwani (Mishawaka, Indiana); Catherine Cassou (Tiburon, California); David Go (South Bend, Indiana); Hsueh-Chia Chang (Granger, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (Notre Dame, Indiana) |
| INVENTOR(S) | Nishant Chetwani (Mishawaka, Indiana); Catherine Cassou (Tiburon, California); David Go (South Bend, Indiana); Hsueh-Chia Chang (Granger, Indiana) |
| ABSTRACT | An alternating current electrospray mass spectrometry device includes an electrospray device having at least one emitter providing a passageway for transmission of an analyte sample. At least one conductive element is in electrical communication with the at least one emitter. A power source generates an alternating current electric field to form a liquid cone at a tip of the emitter and ionizes the analyte sample present in the liquid cone. The frequency of the electric field entrains low mobility ions in the liquid cone. The AC electric field causes the emitter to discharge the liquid cone as a liquid aerosol drop, and a mass spectrometry device analyzes the ionized analyte sample to determine the composition of the contained analyte sample. |
| FILED | Wednesday, April 27, 2011 |
| APPL NO | 13/095288 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/424 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716688 | Strachan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Douglas R. Strachan (Lexington, Kentucky); Stephen L. Johnson (Lexington, Kentucky) |
| ASSIGNEE(S) | The University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Douglas R. Strachan (Lexington, Kentucky); Stephen L. Johnson (Lexington, Kentucky) |
| ABSTRACT | An electronic device includes a first electrode, a second electrode and a nanowire connected between the first and second electrodes to allow electric current flow. The nanowire is made from a conductive material exhibiting a variable resistance due to electromigration. The nanowire is repeatably switchable between two states. A voltage clamp operates through feedback control to maintain the voltage across the nanowire and prevent thermal runaway. |
| FILED | Friday, February 25, 2011 |
| APPL NO | 13/035582 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717046 | Jensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth J. Jensen (Berkeley, California); Alexander K. Zettl (Kensington, California); Jeffrey A. Weldon (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth J. Jensen (Berkeley, California); Alexander K. Zettl (Kensington, California); Jeffrey A. Weldon (Oakland, California) |
| ABSTRACT | A fully-functional radio receiver fabricated from a single nanotube is being disclosed. Simultaneously, a single nanotube can perform the functions of all major components of a radio: antenna, tunable band-pass filter, amplifier, and demodulator. A DC voltage source, as supplied by a battery, can power the radio. Using carrier waves in the commercially relevant 40-400 MHz range and both frequency and amplitude modulation techniques, successful music and voice reception has been demonstrated. Also disclosed are a radio transmitter and a mass sensor using a nanotube resonator device. |
| FILED | Wednesday, September 03, 2008 |
| APPL NO | 12/681760 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/708 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717489 | Ng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yi-Ren Ng (Stanford, California); Patrick M. Hanrahan (Portola Valley, California); Mark A. Horowitz (Menlo Park, California); Marc S. Levoy (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Yi-Ren Ng (Stanford, California); Patrick M. Hanrahan (Portola Valley, California); Mark A. Horowitz (Menlo Park, California); Marc S. Levoy (Stanford, California) |
| ABSTRACT | Various approaches to imaging involve selecting directional and spatial resolution. According to an example embodiment, images are computed using an imaging arrangement to facilitate selective directional and spatial aspects of the detection and processing of light data. Light passed through a main lens is directed to photosensors via a plurality of microlenses. The separation between the microlenses and photosensors is set to facilitate directional and/or spatial resolution in recorded light data, and facilitating refocusing power and/or image resolution in images computed from the recorded light data. In one implementation, the separation is varied between zero and one focal length of the microlenses to respectively facilitate spatial and directional resolution (with increasing directional resolution, hence refocusing power, as the separation approaches one focal length). |
| FILED | Thursday, July 05, 2012 |
| APPL NO | 13/542544 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Television 348/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717558 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Claire Gu (Santa Cruz, California); Yi Zhang (Santa Cruz, California); Chao Shi (Santa Cruz, California); Jin Z. Zhang (Santa Cruz, California); Leo Seballos (Saint Joseph, Minnesota) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Claire Gu (Santa Cruz, California); Yi Zhang (Santa Cruz, California); Chao Shi (Santa Cruz, California); Jin Z. Zhang (Santa Cruz, California); Leo Seballos (Saint Joseph, Minnesota) |
| ABSTRACT | The invention is drawn to a photonic crystal fiber that can be used with nanoparticles to detect and quantify components in a test sample. The invention further relates to methods of using the photonic crystal fiber for detecting chemical and biological analytes, and in use in optical communications. |
| FILED | Wednesday, October 29, 2008 |
| APPL NO | 12/733492 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717657 | Delfyett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter J. Delfyett (Orlando, Florida); Ibrahim T. Ozdur (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orldando, Florida) |
| INVENTOR(S) | Peter J. Delfyett (Orlando, Florida); Ibrahim T. Ozdur (Orlando, Florida) |
| ABSTRACT | An optoelectronic oscillator (OEO) is used to provide a continuous, high Q, modulated signal for a variety of purposes, including a carrier wave for communications, and radar emissions. The OEO of this invention replaces an RF filter in the conventional OEO with an interferometer, preferably a high finesse Fabry-Perot etalon as the mode selector, providing lower phase noise and higher RF frequency stability. |
| FILED | Friday, May 27, 2011 |
| APPL NO | 13/117271 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717669 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiushan Zhu (Tucson, Arizona); Axel Schulzgen (Winter Park, Florida); Nasser Peyghambarian (Tucson, Arizona) |
| ASSIGNEE(S) | The Arizona Board of Regents (Tucson, Arizona) |
| INVENTOR(S) | Xiushan Zhu (Tucson, Arizona); Axel Schulzgen (Winter Park, Florida); Nasser Peyghambarian (Tucson, Arizona) |
| ABSTRACT | A first optical fiber (12) having a first end and a second end is connected to a multimode second optical fiber (14) at the second end. The first optical fiber (12) outputs a substantially single mode optical beam at its second end. The multimode second optical fiber (14) converts light in the optical beam of single mode from the first optical fiber to light of multiple modes, and provides an output beam that has less diffractive spreading than that of a Gaussian beam. |
| FILED | Wednesday, October 14, 2009 |
| APPL NO | 13/124582 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/341.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717673 | Selvin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul R. Selvin (Urbana, Illinois); Sang Hak Lee (Urbana, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Paul R. Selvin (Urbana, Illinois); Sang Hak Lee (Urbana, Illinois) |
| ABSTRACT | An improved microscope stage mount with built-in fiduciary markers is used for fluorescence microscopy, and comprises: (a) an optically-transparent glass plate adapted for specimen mounting and microscope viewing and comprising a specimen mounting area; and (b) a defined and ordered, two-dimensional microscopic array of fiduciary markers, wherein the markers are polymeric pillars affixed to the plate about the specimen mounting area, wherein the markers provide a three-dimensional spatial reference for the specimen. |
| FILED | Saturday, May 28, 2011 |
| APPL NO | 13/118400 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/00 (20130101) G02B 21/34 (20130101) Original (OR) Class G02B 27/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718185 | Giannakis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Saint Paul, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Georgios B. Giannakis (Minnetonka, Minnesota); Xiaoli Ma (Auburn Norcross, Georgia) |
| ABSTRACT | Techniques are described for carrier frequency offset (CFO) and channel estimation of orthogonal frequency division multiplexing (OFDM) transmissions over multiple-input multiple-output (MIMO) frequency-selective fading channels. A wireless transmitter forms blocks of symbols by inserting training symbols within two or more blocks of information-bearing symbols. The transmitter applies a hopping code to each of the blocks of symbols to insert a null subcarrier at a different position within each of the blocks of symbols, and a modulator outputs a wireless signal in accordance with the blocks of symbols. A receiver receives the wireless signal and estimates the CFO, and outputs a stream of estimated symbols based on the estimated CFO. |
| FILED | Tuesday, February 26, 2013 |
| APPL NO | 13/777993 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Pulse or digital communications 375/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718375 | Ouyang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tom Yu Ouyang (Cambridge, Massachusetts); Randall Davis (Weston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Tom Yu Ouyang (Cambridge, Massachusetts); Randall Davis (Weston, Massachusetts) |
| ABSTRACT | Handwriting interpretation tools, such as optical character recognition (OCR), have improved over the years such that OCR is a common tool in business for interpreting typed text and sometimes handwritten text. OCR does not apply well to non-text-only diagrams, such as chemical structure diagrams. A method according to an embodiment of the present invention of interpreting a human-drawn sketch includes determining a local metric indicating whether a candidate symbol belongs to a certain classification based on a set of features. The set of features includes, as a feature, scores generated from feature images of the candidate symbol. Also included is determining a joint metric of multiple candidate symbols based on their respective classifications and interpreting the sketch as a function of the local and joint metrics. Sketches can be chemical composition, biological composition, electrical schematic, mechanical, or any other science- or engineering-based diagrams for which human-drawn symbols have well-known counterparts. |
| FILED | Friday, December 02, 2011 |
| APPL NO | 13/310182 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/187 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718416 | Ioppolo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tindaro Ioppolo (Dallas, Texas); Volkan Otugen (Dallas, Texas); Ulas Ayaz (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | Tindaro Ioppolo (Dallas, Texas); Volkan Otugen (Dallas, Texas); Ulas Ayaz (Dallas, Texas) |
| ABSTRACT | A novel micro-optical electric field sensor exploits morphology-dependent shifts of the optical modes of dielectric cavities to measure temporally- and spatially-resolved of electric field with extremely high sensitivity. The measurement principle is based on the electrostriction effect on the optical modes of dielectric micro-resonators (or micro-cavities) and exploits recent developments in optical fiber and switching technologies. The optical modes are commonly referred to as “whispering gallery modes” (WGM) or “morphology dependent resonances” (MDR). By monitoring the WGM shifts, the electric field causing the electrostriction effect can be determined. Different sensitivities and measurement ranges (maximum measured electric field) can be obtained by using different cavity geometries (for example solid or hollow spheres), polymeric materials (PMMA, PDMS, etc) as well as poling the dielectric material. |
| FILED | Wednesday, November 03, 2010 |
| APPL NO | 12/939168 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718748 | Reinhold |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ralph R. Reinhold (Elgin, Illinois) |
| ASSIGNEE(S) | Kaliber Imaging Inc. (Elgin, Illinois) |
| INVENTOR(S) | Ralph R. Reinhold (Elgin, Illinois) |
| ABSTRACT | A system and methods are provided relating generally to physical activity and more specifically to tools for monitoring and assessing physical activity by capturing images of a subject's movement including range of motion, gait, balance and activities of daily living at different time periods and comparing those images to stored data. |
| FILED | Wednesday, March 28, 2012 |
| APPL NO | 13/432516 |
| ART UNIT | 3777 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery 6/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719252 | Miranker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Paul Miranker (Austin, Texas); Juan Federico Sequeda (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Paul Miranker (Austin, Texas); Juan Federico Sequeda (Austin, Texas) |
| ABSTRACT | This invention is a system and method for integrating relational databases into a semantic web framework utilizing a simple mapping process and the SQL query optimizer present in the SQL database engine. |
| FILED | Friday, October 21, 2011 |
| APPL NO | 13/278907 |
| ART UNIT | 2157 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/713 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719796 | Rosu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Grigore Rosu (Champaign, Illinois); Patrick O. Meredith (Granite City, Illinois); Guo-fang Chen (Fuzhou, China PRC); Yamei Wu (Fuzhou, China PRC) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Grigore Rosu (Champaign, Illinois); Feng Chen (Urbana, Illinois); Patrick O. Meredith (Granite City, Illinois) |
| ABSTRACT | A program trace is obtained and events of the program trace are traversed. For each event identified in traversing the program trace, a trace slice of which the identified event is a part is identified based on the parameter instance of the identified event. For each trace slice of which the identified event is a part, the identified event is added to an end of a record of the trace slice. These parametric trace slices can be used in a variety of different manners, such as for monitoring, mining, and predicting. |
| FILED | Monday, January 24, 2011 |
| APPL NO | 13/012133 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719816 | Troung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thanh N. Troung (Salt Lake City, Utah); Thomas Cook (Salt Lake City, Utah); Manohar Nayak (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Thanh N. Troung (Salt Lake City, Utah); Thomas Cook (Salt Lake City, Utah); Manohar Nayak (Salt Lake City, Utah) |
| ABSTRACT | A system and method are configured to provide a virtual application desktop and communication channel. The system includes a virtual machine executing on an operating system within which multiple applications can concurrently execute. A plurality of applications can each have a protected namespace and be configured to execute using the virtual machine. Each of the plurality of applications can have a request box. A centralized communication engine can be configured to control communications between each request box. In addition, the centralized communication engine can be configured to retrieve, transfer and distribute data between the request boxes of the plurality of applications in response to requests from the plurality of applications. |
| FILED | Tuesday, March 13, 2007 |
| APPL NO | 11/685683 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08713914 | Schmieg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven J. Schmieg (Troy, Michigan); Michael B. Viola (Macomb Township, Michigan); Shi-Wai S. Cheng (Troy, Michigan); Patricia A. Mulawa (Clinton Township, Wisconsin); David L. Hilden (Shelby Township, Michigan); Thompson M. Sloane (Oxford, Michigan); Jong H. Lee (Rochester Hills, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Steven J. Schmieg (Troy, Michigan); Michael B. Viola (Macomb Township, Michigan); Shi-Wai S. Cheng (Troy, Michigan); Patricia A. Mulawa (Clinton Township, Wisconsin); David L. Hilden (Shelby Township, Michigan); Thompson M. Sloane (Oxford, Michigan); Jong H. Lee (Rochester Hills, Michigan) |
| ABSTRACT | A method for monitoring a hydrocarbon-selective catalytic reactor device of an exhaust aftertreatment system of an internal combustion engine operating lean of stoichiometry includes injecting a reductant into an exhaust gas feedstream upstream of the hydrocarbon-selective catalytic reactor device at a predetermined mass flowrate of the reductant, and determining a space velocity associated with a predetermined forward portion of the hydrocarbon-selective catalytic reactor device. When the space velocity exceeds a predetermined threshold space velocity, a temperature differential across the predetermined forward portion of the hydrocarbon-selective catalytic reactor device is determined, and a threshold temperature as a function of the space velocity and the mass flowrate of the reductant is determined. If the temperature differential across the predetermined forward portion of the hydrocarbon-selective catalytic reactor device is below the threshold temperature, operation of the engine is controlled to regenerate the hydrocarbon-selective catalytic reactor device. |
| FILED | Tuesday, September 29, 2009 |
| APPL NO | 12/568754 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/277 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714920 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christian X. Campbell (Oviedo, Florida); Jay A. Morrison (Oviedo, Florida); Allister W. James (Chuluota, Florida); Raymond G. Snider (Orlando, Florida); Daniel M. Eshak (Orlando, Florida); John J. Marra (Winter Springs, Florida); Brian J. Wessell (Orlando, Florida) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | Christian X. Campbell (Oviedo, Florida); Jay A. Morrison (Oviedo, Florida); Allister W. James (Chuluota, Florida); Raymond G. Snider (Orlando, Florida); Daniel M. Eshak (Orlando, Florida); John J. Marra (Winter Springs, Florida); Brian J. Wessell (Orlando, Florida) |
| ABSTRACT | A turbine airfoil (31) with an end portion (42) that tapers (44) toward the end (43) of the airfoil. A ridge (46) extends around the end portion. It has proximal (66) and distal (67) sides. A shroud platform (50) is bi-cast onto the end portion around the ridge without bonding. Cooling shrinks the platform into compression (62) on the end portion (42) of the airfoil. Gaps between the airfoil and platform are formed using a fugitive material (56) in the bi-casting stage. These gaps are designed in combination with the taper angle (44) to accommodate differential thermal expansion while maintaining a gas seal along the contact surfaces. The taper angle (44) may vary from lesser on the pressure side (36) to greater on the suction side (38) of the airfoil. A collar portion (52) of the platform provides sufficient contact area for connection stability. |
| FILED | Thursday, April 01, 2010 |
| APPL NO | 12/752460 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/191 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08714926 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ching-Pang Lee (Cincinnati, Ohio); John J. Marra (Winter Springs, Florida) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida); Mikro Systems, Inc. (Charlottesville, Virginia) |
| INVENTOR(S) | Ching-Pang Lee (Cincinnati, Ohio); John J. Marra (Winter Springs, Florida) |
| ABSTRACT | A mesh (35) of cooling channels (35A, 35B) with an array of cooling channel intersections (42) in a wall (21, 22) of a turbine component. A mixing chamber (42A-C) at each intersection is wider (W1, W2)) than a width (W) of each of the cooling channels connected to the mixing chamber. The mixing chamber promotes swirl, and slows the coolant for more efficient and uniform cooling. A series of cooling meshes (M1, M2) may be separated by mixing manifolds (44), which may have film cooling holes (46) and/or coolant refresher holes (48). |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/884486 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/187 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715392 | Liu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wei Liu (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Wei Liu (Richland, Washington) |
| ABSTRACT | Disclosed are membranes and methods for making the same, which membranes provide improved permeability, stability, and cost-effective manufacturability, for separating CO2 from gas streams such as flue gas streams. High CO2 permeation flux is achieved by immobilizing an ultra-thin, optionally catalyzed fluid layer onto a meso-porous modification layer on a thin, porous inorganic substrate such as a porous metallic substrate. The CO2-selective liquid fluid blocks non-selective pores, and allows for selective absorption of CO2 from gas mixtures such as flue gas mixtures and subsequent transport to the permeation side of the membrane. Carbon dioxide permeance levels are in the order of 1.0×10−6 mol/(m2sPa) or better. Methods for making such membranes allow commercial scale membrane manufacturing at highly cost-effective rates when compared to conventional commercial-scale CO2 separation processes and equipment for the same and such membranes are operable on an industrial use scale. |
| FILED | Friday, October 08, 2010 |
| APPL NO | 12/901119 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation: Processes 095/51 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715653 | Turley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eva A. Turley (London, Canada); Mina J. Bissell (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eva A. Turley (London, Canada); Mina J. Bissell (Berkeley, California) |
| ABSTRACT | Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described. |
| FILED | Wednesday, November 21, 2007 |
| APPL NO | 12/515405 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715882 | Sopchak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David A. Sopchak (Oakland, California); Jeffrey D. Morse (Westhampton, Massachusetts); Ravindra S. Upadhye (Pleasanton, California); Jack Kotovsky (Alameda, California); Robert T. Graff (Modesto, California) |
| ASSIGNEE(S) | Lawrene Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | David A. Sopchak (Oakland, California); Jeffrey D. Morse (Westhampton, Massachusetts); Ravindra S. Upadhye (Pleasanton, California); Jack Kotovsky (Alameda, California); Robert T. Graff (Modesto, California) |
| ABSTRACT | A phosphoric acid fuel cell according to one embodiment includes an array of microchannels defined by a porous electrolyte support structure extending between bottom and upper support layers, the microchannels including fuel and oxidant microchannels; fuel electrodes formed along some of the microchannels; and air electrodes formed along other of the microchannels. A method of making a phosphoric acid fuel cell according to one embodiment includes etching an array of microchannels in a substrate, thereby forming walls between the microchannels; processing the walls to make the walls porous, thereby forming a porous electrolyte support structure; forming anode electrodes along some of the walls; forming cathode electrodes along other of the walls; and filling the porous electrolyte support structure with a phosphoric acid electrolyte. Additional embodiments are also disclosed. |
| FILED | Thursday, July 01, 2010 |
| APPL NO | 12/829331 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715973 | Pfleger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian Frederick Pfleger (Madison, Wisconsin); Matthew Brett Begemann (Madison, Wisconsin) |
| ABSTRACT | Organic acid-tolerant microorganisms and methods of using same. The organic acid-tolerant microorganisms comprise modifications that reduce or ablate AcsA activity or AcsA homolog activity. The modifications increase tolerance of the microorganisms to such organic acids as 3-hydroxypropionic acid (3HP), acrylic acid, and propionic acid. Further modifications to the microorganisms such as increasing expression of malonyl-CoA reductase and/or acetyl-CoA carboxylase provide or increase the ability of the microorganisms to produce 3HP. Methods of generating an organic acid with the modified microorganisms are provided. Methods of using acsA or homologs thereof as counter-selectable markers include replacing acsA or homologs thereof in cells with genes of interest and selecting for the cells comprising the genes of interest with amounts of organic acids effective to inhibit growth of cells harboring acsA or the homologs. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/798835 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/141 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715994 | Morant |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes Inc. (Davis, California) |
| INVENTOR(S) | Marc Dominique Morant (Copenhagen, Denmark) |
| ABSTRACT | The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 13/678638 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715995 | Morant |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes A/S (Bagsvaerd, Denmark); Novozymes Inc. (Davis, California) |
| INVENTOR(S) | Marc Dominique Morant (Copenhagen, Denmark) |
| ABSTRACT | The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 13/678647 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715997 | Aehle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wolfgang Aehle (Leiden, Netherlands); Frits Goedegebuur (Leiden, Netherlands); Lydia Dankmeyer (Leiden, Netherlands); Colin Mitchinson (Half Moon Bay, California); Paulien Neefe (Leiden, Netherlands); Bradley Kelemen (Menlo Park, California); Robert Caldwell (Belmont, California); Pauline Teunissen (Leiden, Netherlands) |
| ASSIGNEE(S) | Danisco US Inc. (Palo Alto, California) |
| INVENTOR(S) | Wolfgang Aehle (Leiden, Netherlands); Frits Goedegebuur (Leiden, Netherlands); Lydia Dankmeyer (Leiden, Netherlands); Colin Mitchinson (Half Moon Bay, California); Paulien Neefe (Leiden, Netherlands); Bradley Kelemen (Menlo Park, California); Robert Caldwell (Belmont, California); Pauline Teunissen (Leiden, Netherlands) |
| ABSTRACT | Described herein are variants of H. jecorina CBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability. |
| FILED | Thursday, July 07, 2011 |
| APPL NO | 13/178227 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716002 | Yomano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lorraine P. Yomano (Gainesville, Florida); Sean W. York (Gainesville, Florida); Shengde Zhou (Dekalb, Illinois); Keelnatham Shanmugam (Gainesville, Florida); Lonnie O. Ingram (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Lorraine P. Yomano (Gainesville, Florida); Sean W. York (Gainesville, Florida); Shengde Zhou (Dekalb, Illinois); Keelnatham Shanmugam (Gainesville, Florida); Lonnie O. Ingram (Gainesville, Florida) |
| ABSTRACT | The invention provides recombinant bacteria, which comprise a full complement of heterologous ethanol production genes. Expression of the full complement of heterologous ethanol production genes causes the recombinant bacteria to produce ethanol as the primary fermentation product when grown in mineral salts medium, without the addition of complex nutrients. Methods for producing the recombinant bacteria and methods for producing ethanol using the recombinant bacteria are also disclosed. |
| FILED | Wednesday, August 08, 2007 |
| APPL NO | 12/375484 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716011 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brady D. Lee (Idaho Falls, Idaho); David N. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho); David W. Reed (Idaho Falls, Idaho); Jeffrey A. Lacey (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Brady D. Lee (Idaho Falls, Idaho); David N. Thompson (Idaho Falls, Idaho); William A. Apel (Jackson, Wyoming); Vicki S. Thompson (Idaho Falls, Idaho); David W. Reed (Idaho Falls, Idaho); Jeffrey A. Lacey (Idaho Falls, Idaho) |
| ABSTRACT | Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of modulating transcription or transcription or transcriptional control using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius. |
| FILED | Friday, February 20, 2009 |
| APPL NO | 12/380008 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716637 | Ripley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edward B. Ripley (Knoxville, Tennessee); Glenn L. Pfennigwerth (Knoxville, Tennessee) |
| ASSIGNEE(S) | Babcock and Wilcox Technical Services Y-12, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Edward B. Ripley (Knoxville, Tennessee); Glenn L. Pfennigwerth (Knoxville, Tennessee) |
| ABSTRACT | Systems for heat treating materials are presented. The systems typically involve a fluidized bed that contains granulated heat treating material. In some embodiments a fluid, such as an inert gas, is flowed through the granulated heat treating medium, which homogenizes the temperature of the heat treating medium. In some embodiments the fluid may be heated in a heating vessel and flowed into the process chamber where the fluid is then flowed through the granulated heat treating medium. In some embodiments the heat treating material may be liquid or granulated heat treating material and the heat treating material may be circulated through a heating vessel into a process chamber where the heat treating material contacts the material to be heat treated. Microwave energy may be used to provide the source of heat for heat treating systems. |
| FILED | Thursday, June 18, 2009 |
| APPL NO | 12/486823 |
| ART UNIT | 3742 — Organic Chemistry |
| CURRENT CPC | Electric heating 219/679 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717046 | Jensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth J. Jensen (Berkeley, California); Alexander K. Zettl (Kensington, California); Jeffrey A. Weldon (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth J. Jensen (Berkeley, California); Alexander K. Zettl (Kensington, California); Jeffrey A. Weldon (Oakland, California) |
| ABSTRACT | A fully-functional radio receiver fabricated from a single nanotube is being disclosed. Simultaneously, a single nanotube can perform the functions of all major components of a radio: antenna, tunable band-pass filter, amplifier, and demodulator. A DC voltage source, as supplied by a battery, can power the radio. Using carrier waves in the commercially relevant 40-400 MHz range and both frequency and amplitude modulation techniques, successful music and voice reception has been demonstrated. Also disclosed are a radio transmitter and a mass sensor using a nanotube resonator device. |
| FILED | Wednesday, September 03, 2008 |
| APPL NO | 12/681760 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/708 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717223 | Chambers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David H. Chambers (Livermore, California); David W. Paglieroni (Pleasanton, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | David H. Chambers (Livermore, California); David W. Paglieroni (Pleasanton, California) |
| ABSTRACT | The classification system represents a detected object with a feature vector derived from the return signals acquired by an array of N transceivers operating in multistatic mode. The classification system generates the feature vector by transforming the real-valued return signals into complex-valued spectra, using, for example, a Fast Fourier Transform. The classification system then generates a feature vector of singular values for each user-designated spectral sub-band by applying a singular value decomposition (SVD) to the N×N square complex-valued matrix formed from sub-band samples associated with all possible transmitter-receiver pairs. The resulting feature vector of singular values may be transformed into a feature vector of singular value likelihoods and then subjected to a multi-category linear or neural network classifier for object classification. |
| FILED | Friday, August 26, 2011 |
| APPL NO | 13/219435 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717564 | Bishop |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James K. B. Bishop (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James K. B. Bishop (Berkeley, California) |
| ABSTRACT | A robotic optical sedimentation recorder is described for the recordation of carbon flux in the oceans wherein both POC and PIC particles are captured at the open end of a submersible sampling platform, the captured particles allowed to drift down onto a collection plate where they can be imaged over time. The particles are imaged using three separate light sources, activated in sequence, one source being a back light, a second source being a side light to provide dark field illumination, and a third source comprising a cross polarized light source to illuminate birefringent particles. The recorder in one embodiment is attached to a buoyancy unit which is capable upon command for bringing the sedimentation recorder to a programmed depth below the ocean surface during recordation mode, and on command returning the unit to the ocean surface for transmission of recorded data and receipt of new instructions. The combined unit is provided with its own power source and is designed to operate autonomously in the ocean for extended periods of time. |
| FILED | Friday, November 07, 2008 |
| APPL NO | 12/742395 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/364 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717850 | Daley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tom M. Daley (Oakland, California); Ray D. Solbau (Crescent City, California); Ernest L. Majer (Orinda, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Tom M. Daley (Oakland, California); Ray D. Solbau (Crescent City, California); Ernest L. Majer (Orinda, California) |
| ABSTRACT | A piezoelectric borehole source capable of permanent or semipermanent insertion into a well for uninterrupted well operations is described. The source itself comprises a series of piezoelectric rings mounted to an insulative mandrel internally sized to fit over a section of well tubing, the rings encased in a protective housing and electrically connected to a power source. Providing an AC voltage to the rings will cause expansion and contraction sufficient to create a sonic pulse. The piezoelectric borehole source fits into a standard well, and allows for uninterrupted pass-through of production tubing, and other tubing and electrical cables. Testing using the source may be done at any time, even concurrent with well operations, during standard production. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 12/444136 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718218 | Policke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Babcock and Wilcox Technical Services Group, Inc. (Lynchburg, Virginia) |
| ASSIGNEE(S) | Babcock and Wilcox Technical Services Group, Inc. (Lynchburg, Virginia) |
| INVENTOR(S) | Timothy A Policke (Forest, Virginia); Erik T Nygaard (Lynchburg, Virginia) |
| ABSTRACT | The present invention relates generally to both a system and method for determining the composition of an off-gas from a solution nuclear reactor (e.g., an Aqueous Homogeneous Reactor (AHR)) and the composition of the fissioning solution from those measurements. In one embodiment, the present invention utilizes at least one quadrupole mass spectrometer (QMS) in a system and/or method designed to determine at least one or more of: (i) the rate of production of at least one gas and/or gas species from a nuclear reactor; (ii) the effect on pH by one or more nitrogen species; (iii) the rate of production of one or more fission gases; and/or (iv) the effect on pH of at least one gas and/or gas species other than one or more nitrogen species from a nuclear reactor. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/796461 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/156 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718416 | Ioppolo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tindaro Ioppolo (Dallas, Texas); Volkan Otugen (Dallas, Texas); Ulas Ayaz (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | Tindaro Ioppolo (Dallas, Texas); Volkan Otugen (Dallas, Texas); Ulas Ayaz (Dallas, Texas) |
| ABSTRACT | A novel micro-optical electric field sensor exploits morphology-dependent shifts of the optical modes of dielectric cavities to measure temporally- and spatially-resolved of electric field with extremely high sensitivity. The measurement principle is based on the electrostriction effect on the optical modes of dielectric micro-resonators (or micro-cavities) and exploits recent developments in optical fiber and switching technologies. The optical modes are commonly referred to as “whispering gallery modes” (WGM) or “morphology dependent resonances” (MDR). By monitoring the WGM shifts, the electric field causing the electrostriction effect can be determined. Different sensitivities and measurement ranges (maximum measured electric field) can be obtained by using different cavity geometries (for example solid or hollow spheres), polymeric materials (PMMA, PDMS, etc) as well as poling the dielectric material. |
| FILED | Wednesday, November 03, 2010 |
| APPL NO | 12/939168 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719925 | Berg |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael J. Berg (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael J. Berg (Albuquerque, New Mexico) |
| ABSTRACT | A monitoring device for monitoring transactions on a bus includes content-addressable memory (“CAM”) and a response policy unit. The CAM includes an input coupled to receive a bus transaction tag based on bus traffic on the bus. The CAM stores data tags associated with rules of a security policy to compare the bus transaction tag to the data tags. The CAM generates an output signal indicating whether one or more matches occurred. The response policy unit is coupled to the CAM to receive the output signal from the CAM and to execute a policy action in response to the output signal. |
| FILED | Tuesday, August 25, 2009 |
| APPL NO | 12/546740 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30985 (20130101) G06F 21/50 (20130101) G06F 21/55 (20130101) G06F 21/56 (20130101) G06F 21/70 (20130101) G06F 21/85 (20130101) G06F 21/554 (20130101) G06F 21/561 (20130101) G06F 21/567 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719961 | Kalinin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sergei V. Kalinin (Knoxville, Tennessee); Nina Balke (Knoxville, Tennessee); Amit Kumar (Oak Ridge, Tennessee); Nancy J. Dudney (Knoxville, Tennessee); Stephen Jesse (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Sergei V. Kalinin (Knoxville, Tennessee); Nina Balke (Knoxville, Tennessee); Amit Kumar (Oak Ridge, Tennessee); Nancy J. Dudney (Knoxville, Tennessee); Stephen Jesse (Knoxville, Tennessee) |
| ABSTRACT | A method and system for probing mobile ion diffusivity and electrochemical reactivity on a nanometer length scale of a free electrochemically active surface includes a control module that biases the surface of the material. An electrical excitation signal is applied to the material and induces the movement of mobile ions. An SPM probe in contact with the surface of the material detects the displacement of mobile ions at the surface of the material. A detector measures an electromechanical strain response at the surface of the material based on the movement and reactions of the mobile ions. The use of an SPM tip to detect local deformations allows highly reproducible measurements in an ambient environment without visible changes in surface structure. The measurements illustrate effective spatial resolution comparable with defect spacing and well below characteristic grain sizes of the material. |
| FILED | Tuesday, November 08, 2011 |
| APPL NO | 13/291480 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/51 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08715155 | Schrick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | F. Neal Schrick (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | F. Neal Schrick (Knoxville, Tennessee) |
| ABSTRACT | An embryo that is transferred into the uterus of a recipient female is protected from toxic effects of prostaglandin F2α by exposing the embryo, or an oocyte from which the embryo is produced, to a prostaglandin antagonist. |
| FILED | Tuesday, July 29, 2008 |
| APPL NO | 12/220978 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Surgery 6/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715763 | McHugh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tara H. McHugh (El Cerrito, California); Matthew D. de Bord (Manteca, California); Carl W. Olsen (Davis, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Department of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Tara H. McHugh (El Cerrito, California); Matthew D. de Bord (Manteca, California); Carl W. Olsen (Davis, California) |
| ABSTRACT | The present invention is directed to monolayer, bilayer, and multilayer films made from fruit, vegetable or a combination thereof, which films have the thinness, strength, flexibility, and crispness to serve as alternates or substitutes for seaweed-based films such as nori, while providing the nutrition and flavor of fruits and vegetables. The films are useful for wrapping around a multiplicity of foods, and can be used to provide wrapped foods, including for example fruit and vegetable wrapped sushi and onigiri. |
| FILED | Friday, October 28, 2011 |
| APPL NO | 13/284496 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Food or edible material: Processes, compositions, and products 426/575 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08716001 — Trichoderma strains that induce resistance to plant diseases and/or increase plant growth
| US 08716001 | Harman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gary E. Harman (Geneva, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Gary E. Harman (Geneva, New York) |
| ABSTRACT | A method for enhancing growth of plants comprising contacting a Trichoderma strain with the plant or a plant seed under conditions effective for the Trichoderma strain to colonize the roots of the plant or a plant grown from the plant seed, thereby creating a plant-Trichoderma system. The plant or plant seed is grown under conditions effective to sustain the plant-Trichoderma system in a planting medium and to enhance plant growth. The Trichoderma strain is selected from the group consisting of Trichoderma atroviride strain WW10TC4 (ATCC accession number PTA 9707), Trichoderma harzianum strain RR17Bc (ATCC accession number PTA 9708), Trichoderma harzianum strain F11 Bab (ATCC accession number PTA 9709), and combinations thereof. Methods of enhancing resistance of plants to abiotic stress, increasing nitrogen use efficacy in plants, reducing nitrous oxide emissions in air, reducing leaching of nitrates into soil and water, and enhancing sequestration of carbon from air are disclosed. |
| FILED | Monday, February 08, 2010 |
| APPL NO | 13/148255 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716002 | Yomano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lorraine P. Yomano (Gainesville, Florida); Sean W. York (Gainesville, Florida); Shengde Zhou (Dekalb, Illinois); Keelnatham Shanmugam (Gainesville, Florida); Lonnie O. Ingram (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Lorraine P. Yomano (Gainesville, Florida); Sean W. York (Gainesville, Florida); Shengde Zhou (Dekalb, Illinois); Keelnatham Shanmugam (Gainesville, Florida); Lonnie O. Ingram (Gainesville, Florida) |
| ABSTRACT | The invention provides recombinant bacteria, which comprise a full complement of heterologous ethanol production genes. Expression of the full complement of heterologous ethanol production genes causes the recombinant bacteria to produce ethanol as the primary fermentation product when grown in mineral salts medium, without the addition of complex nutrients. Methods for producing the recombinant bacteria and methods for producing ethanol using the recombinant bacteria are also disclosed. |
| FILED | Wednesday, August 08, 2007 |
| APPL NO | 12/375484 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716206 | Bredsguard |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biosynthetic Technologies, LLC (Irvine, California) |
| ASSIGNEE(S) | Biosynthetic Technologies, LLC (Irvine, California) |
| INVENTOR(S) | Jakob Bredsguard (Lake Forest, California) |
| ABSTRACT | Provided herein are compounds, including those of the Formula II in which n is an integer equal to or greater than 1; R2, is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R3, and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Also provided are compositions containing such compounds and methods of making both compounds and compositions thereof. |
| FILED | Thursday, April 18, 2013 |
| APPL NO | 13/865520 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Solid anti-friction devices, materials therefor, lubricant or separant compositions for moving solid surfaces, and miscellaneous mineral oil compositions 58/465 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716460 | Alfano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James R. Alfano (Lincoln, Nebraska); Alan Collmer (Ithaca, New York); Samuel W. Cartinhour (Ithaca, New York); David J. Schneider (Trumansburg, New York); Xiaoyan Tang (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas); The Board of Regents of the University of Nebraska (Lincoln, Nebraska); Cornell Research Foundation, Inc. (Ithaca, New York); The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | James R. Alfano (Lincoln, Nebraska); Alan Collmer (Ithaca, New York); Samuel W. Cartinhour (Ithaca, New York); David J. Schneider (Trumansburg, New York); Xiaoyan Tang (Manhattan, Kansas) |
| ABSTRACT | One aspect of the present invention relates to isolated nucleic acid molecules encoding avirulence proteins or polypeptides of Pseudomonas syringae pv. syringae DC 3000, or nucleic acid molecules which are complementary thereto. Expression vectors, host cells, and transgenic plants which include the DNA molecules of the present invention are also disclosed. Another aspect relates to the isolated proteins or polypeptides and compositions containing the same. The various nucleic acid molecules and proteins of the present invention can be used to impart disease resistance to a plant, make a plant hypersusceptible to colonization by nonpathogenic bacteria, modify a metabolic pathway in a cell, cause eukaryotic cell death and treat a cancerous condition, as well as inhibit programmed cell death. |
| FILED | Wednesday, December 27, 2006 |
| APPL NO | 11/616609 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/23.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP24422 | Freyre |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rosanna Freyre (Gainesville, Florida) |
| ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
| INVENTOR(S) | Rosanna Freyre (Gainesville, Florida) |
| ABSTRACT | ‘R10-102’ is a new Ruellia plant distinguished by having excellent landscape performance, violet flowers, and no fruiting, as disclosed. |
| FILED | Friday, June 08, 2012 |
| APPL NO | 13/507163 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/226 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP24431 | Deng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
| ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
| INVENTOR(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
| ABSTRACT | A new and distinct cultivar of Caladium named ‘UF-18-49’ is disclosed. ‘UF-18-49’ is uniquely characterized with large fancy leaves, a large red center, strong vigor, excellent sunburn tolerance, and demonstrated potential to produce attractive plants when grown in containers or outdoor landscapes. |
| FILED | Friday, August 10, 2012 |
| APPL NO | 13/508000 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP24432 | Deng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
| ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
| INVENTOR(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
| ABSTRACT | A new and distinct cultivar of Caladium named ‘UF-172’ is disclosed. ‘UF-172’ is uniquely characterized with large attractive pink blotches on leaf blades with red petioles, outstanding potential to produce tubers in field production, production of attractive pot plants when tubers are forced in containers, and production of attractive and sun-tolerant plants in outdoor sunny or shady landscapes. |
| FILED | Friday, August 10, 2012 |
| APPL NO | 13/507999 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08714491 | Simon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xavier D. Simon (Aliso Viejo, California); Michael J. Robinson (Huntington Beach, California); Thomas L. Andrews (Newport Beach, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Xavier D. Simon (Aliso Viejo, California); Michael J. Robinson (Huntington Beach, California); Thomas L. Andrews (Newport Beach, California) |
| ABSTRACT | The thermal protection system disclosed herein is suitable for use with a spacecraft such as a reentry module or vehicle, where the spacecraft has a convex surface to be protected. An embodiment of the thermal protection system includes a plurality of heat resistant panels, each having an outer surface configured for exposure to atmosphere, an inner surface opposite the outer surface and configured for attachment to the convex surface of the spacecraft, and a joint edge defined between the outer surface and the inner surface. The joint edges of adjacent ones of the heat resistant panels are configured to mate with each other to form staggered joints that run between the peak of the convex surface and the base section of the convex surface. |
| FILED | Friday, September 28, 2007 |
| APPL NO | 11/864619 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/159.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08715886 | Cable et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas L Cable (Olmsted Falls, Ohio); John A Setlock (Grafton, Ohio); Serene C Farmer (Sagamore Hills, Ohio) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Thomas L Cable (Olmsted Falls, Ohio); John A Setlock (Grafton, Ohio); Serene C Farmer (Sagamore Hills, Ohio) |
| ABSTRACT | The invention is a novel solid oxide fuel cell (SOFC) stack comprising individual bi-electrode supported fuel cells in which an electrolyte layer is supported between porous electrodes. The porous electrodes may be made from graded pore ceramic tape that has been created by the freeze cast method followed by freeze-drying. Each piece of graded pore tape later becomes a graded pore electrode scaffold that, subsequent to sintering, is made into either an anode or a cathode. The electrode scaffold comprising the anode includes a layer of liquid metal. The pores of the electrode scaffolds gradually increase in diameter as the layer extends away from the electrolyte layer. As a result of this diameter increase, any forces that would tend to pull the liquid metal away from the electrolyte are reduced while maintaining a diffusion path for the fuel. Advantageously, the fuel cell of the invention may utilize a hydrocarbon fuel without pre-processing to remove sulfur. |
| FILED | Tuesday, September 28, 2010 |
| APPL NO | 12/892339 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/535 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717012 | Wincheski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Russell A. Wincheski (Williamsburg, Virginia); John W. Simpson (Yorktown, Virginia) |
| ASSIGNEE(S) | The United States of America as respresented by the United States National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Russell A. Wincheski (Williamsburg, Virginia); John W. Simpson (Yorktown, Virginia) |
| ABSTRACT | An eddy current probe includes an excitation coil for coupling to a low-frequency alternating current (AC) source. A magnetoresistive sensor is centrally disposed within and at one end of the excitation coil to thereby define a sensing end of the probe. A tubular flux-focusing lens is disposed between the excitation coil and the magnetoresistive sensor. An excitation wire is spaced apart from the magnetoresistive sensor in a plane that is perpendicular to the sensor's axis of sensitivity and such that, when the sensing end of the eddy current probe is positioned adjacent to the surface of a structure, the excitation wire is disposed between the magnetoresistive sensor and the surface of the structure. The excitation wire is coupled to a high-frequency AC source. The excitation coil and flux-focusing lens can be omitted when only surface inspection is required. |
| FILED | Friday, April 27, 2012 |
| APPL NO | 13/457687 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/239 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717558 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Claire Gu (Santa Cruz, California); Yi Zhang (Santa Cruz, California); Chao Shi (Santa Cruz, California); Jin Z. Zhang (Santa Cruz, California); Leo Seballos (Saint Joseph, Minnesota) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Claire Gu (Santa Cruz, California); Yi Zhang (Santa Cruz, California); Chao Shi (Santa Cruz, California); Jin Z. Zhang (Santa Cruz, California); Leo Seballos (Saint Joseph, Minnesota) |
| ABSTRACT | The invention is drawn to a photonic crystal fiber that can be used with nanoparticles to detect and quantify components in a test sample. The invention further relates to methods of using the photonic crystal fiber for detecting chemical and biological analytes, and in use in optical communications. |
| FILED | Wednesday, October 29, 2008 |
| APPL NO | 12/733492 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08719796 | Rosu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Grigore Rosu (Champaign, Illinois); Patrick O. Meredith (Granite City, Illinois); Guo-fang Chen (Fuzhou, China PRC); Yamei Wu (Fuzhou, China PRC) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Grigore Rosu (Champaign, Illinois); Feng Chen (Urbana, Illinois); Patrick O. Meredith (Granite City, Illinois) |
| ABSTRACT | A program trace is obtained and events of the program trace are traversed. For each event identified in traversing the program trace, a trace slice of which the identified event is a part is identified based on the parameter instance of the identified event. For each trace slice of which the identified event is a part, the identified event is added to an end of a record of the trace slice. These parametric trace slices can be used in a variety of different manners, such as for monitoring, mining, and predicting. |
| FILED | Monday, January 24, 2011 |
| APPL NO | 13/012133 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Data processing: Software development, installation, and management 717/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08716220 | Tezapsidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nikolaos Tezapsidis (West Orange, New Jersey); Steven J. Greco (Carlstadt, New Jersey); Mark Smith (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikolaos Tezapsidis (West Orange, New Jersey); Steven J. Greco (Carlstadt, New Jersey); Mark Smith (Cleveland, Ohio) |
| ABSTRACT | The present disclosure provides compositions containing a leptin product and methods of clinical therapy and diagnostic methods for progressive cognitive disorders. According to one aspect, the described invention provides a method for treating a progressive cognitive disorder. According to another aspect, the described invention provides a method for improving resilience of cognitive function in a subject in need thereof. According to another aspect, the described invention provides a method for identifying an effective therapeutic agent for treating a progressive cognitive dysfunction disease or disorder that results from at least one of accumulation of Aβ, hyperphosphorylation of tau, or accumulation of neurofibrillary tangles. |
| FILED | Wednesday, November 04, 2009 |
| APPL NO | 12/612613 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/5.800 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716448 | Schellenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Willem Stemmer (Los Gatos, California); Chia-wei Wang (Milpitas, California); Benjamin Spink (San Carlos, California); Nathan Geething (Santa Clara, California); Wayne To (Fremont, California) |
| ASSIGNEE(S) | Amunix Operating Inc. (Mountain View, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Sunnyvale, California); Willem Stemmer (Los Gatos, California); Chia-wei Wang (Milpitas, California); Benjamin Spink (San Carlos, California); Nathan Geething (Santa Clara, California); Wayne To (Fremont, California) |
| ABSTRACT | The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions. |
| FILED | Monday, August 02, 2010 |
| APPL NO | 12/806005 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/384 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716558 | Naleway et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John J. Naleway (Eugene, Oregon); Rachel A. Howard (Eugene, Oregon) |
| ASSIGNEE(S) | Marker Gene Technologies, Inc. (Eugene, Oregon) |
| INVENTOR(S) | John J. Naleway (Eugene, Oregon); Rachel A. Howard (Eugene, Oregon) |
| ABSTRACT | Novel pro-drugs and methods for their use to alter the growth and biological characteristics of living cells, tissues, or whole organisms are described. Such cells may include animal cells, plant cells and bacterial cells. The methods allow for selective activation of the pro-drugs at or near transformant host cells expressing a gene for an enzyme that activates the pro-drugs. Pro-drugs according to a preferred embodiment of the invention are conjugates of a bioactive compound and a chemical group that is capable of being cleaved from the bioactive compound by action of an enzyme. Methods according to this invention include, (a) introducing into targeted cells a gene encoding an enzyme and (b) administering a pro-drug, wherein the enzyme releases the pro-drug from conjugation. In a preferred embodiment of the invention, the gene encoding the enzyme is a marker gene. Methods according to a preferred embodiment of the invention include altering protein production in a plant cell such as altering glycosylation of a protein produced by the plant cell. |
| FILED | Monday, December 19, 2005 |
| APPL NO | 11/316114 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718421 | Morton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul A. Morton (West Friendship, Maryland); Jacob Khurgin (Baltimore, Maryland) |
| ASSIGNEE(S) | Morton Photonics (West Friendship, Maryland) |
| INVENTOR(S) | Paul A. Morton (West Friendship, Maryland); Jacob Khurgin (Baltimore, Maryland) |
| ABSTRACT | This invention provides an optical device comprising a large group of non-uniform resonators operating cumulatively as a ‘super-ring’ to provide a controllable group delay with large bandwidth. The super-ring tuning is performed by a single control. The device may include two super-rings, each includes a large number of resonators with a resonant frequencies centered around ω1 and ω2 respectively. The invention provides multiple ways to improve the delay duration, bandwidth and the tuning speed, and overcomes the issue of non-uniformity of resonance frequency for devices incorporating multiple optical resonators. |
| FILED | Thursday, March 10, 2011 |
| APPL NO | 13/044669 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 08718671 | Barbeau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida) |
| ABSTRACT | A method of buffering location data on a mobile device. The method transmits location data packets via an unreliable protocol to a receiving device and buffers a copy of the location data packet. Periodically, the method also transmits a location data packet via a reliable protocol to the receiving device. When no acknowledgement is received from the receiving device, the location data sent via the reliable protocol is buffered to memory. Once an acknowledgement is received from the receiving device, all of the buffered location data is sent to the receiving device via an unreliable protocol. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/082722 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/456.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08718911 | McGuffin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tom McGuffin (Bellevue, Washington) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Tom McGuffin (Bellevue, Washington) |
| ABSTRACT | A system and method are provided for presenting a taxi route for an aircraft at an airport. The method, for example, includes, but is not limited to receiving, by a processor, the taxi route, translating, by the processor, the taxi route into a graphical representation, displaying, on an aircraft display, a map of the airport and the graphical representation, and displaying, a location of a hold short instruction on the aircraft display. |
| FILED | Friday, April 01, 2011 |
| APPL NO | 13/078715 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08716266 | Acevedo-Duncan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mildred E. Acevedo-Duncan (Plant City, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Mildred E. Acevedo-Duncan (Plant City, Florida) |
| ABSTRACT | The present invention pertains to use of PKC-iota inhibitors for treatment of glioma. In a specific embodiment, the treatment method comprises administering ICA-1 or a salt thereof to a subject with glioma. In another embodiment, the treatment method comprises contacting glioma cells with an effective amount of ICA-1 or a salt thereof. |
| FILED | Tuesday, September 04, 2012 |
| APPL NO | 13/602708 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/94 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08716436 | Zadina et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James E. Zadina (Metairie, Louisiana); Laszlo Hackler (Metairie, Louisiana) |
| ASSIGNEE(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana); U.S. Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | James E. Zadina (Metairie, Louisiana); Laszlo Hackler (Metairie, Louisiana) |
| ABSTRACT | The invention relates to cyclic peptide agonists that bind to the mu (morphine) opioid receptor and their use in the treatment of acute and/or chronic pain. Embodiments of the invention are directed to cyclic pentapeptide and hexapeptide analogs of endomorphin that have (i) a carboxy-terminal extension with an amidated hydrophilic amino acid and (ii) a substitution in amino acid position 2. These peptide analogs exhibit decreased tolerance relative to morphine, increased solubility compared to similar tetrapeptide analogs, while maintaining favorable or improved therapeutic ratios of analgesia to side effects. |
| FILED | Tuesday, May 22, 2012 |
| APPL NO | 13/477423 |
| ART UNIT | 1676 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/317 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Classified Government Agency
| US 08716651 | De Ruyter |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Howard M. De Ruyter (Torrance, California) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Howard M. De Ruyter (Torrance, California) |
| ABSTRACT | A calibration system for a detector includes a base member, a plurality of radiation sources fixedly attached to the base member, and a positioning mechanism attached to the base member. Each radiation source is maintained at a different temperature and is configured to emit electromagnetic radiation. The positioning mechanism includes a movable member having a single degree of freedom with respect to the base member, and a plurality of optical elements arranged on the movable member. Each optical element corresponds to one of the radiation sources and each optical element is configured to at least be movable between a calibration position and a non-calibration position. When the optical element is in the calibration position, the optical element is configured to receive the electromagnetic radiation from its corresponding radiation source and to reflect the electromagnetic radiation to a detector. |
| FILED | Thursday, August 18, 2011 |
| APPL NO | 13/212875 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08715591 | Gaitan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Gaitan (Gaithersburg, Maryland); Andreas Jahn (Zürich, Switzerland); Laurie E. Locascio (Gaithersburg, Maryland); Wyatt Vreeland (Gaithersburg, Maryland); Joseph E. Reiner (Fredericksburg, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Commerce, the National Institute of Standards and Technology (Washington, District of Columbia) |
| INVENTOR(S) | Michael Gaitan (Gaithersburg, Maryland); Andreas Jahn (Zürich, Switzerland); Laurie E. Locascio (Gaithersburg, Maryland); Wyatt Vreeland (Gaithersburg, Maryland); Joseph E. Reiner (Fredericksburg, Virginia) |
| ABSTRACT | An apparatus to create a homogenous liposome population without post-processing using laminar flow/diffusive mixing, and for reducing waste discharge of the therapeutic or compound to be encapsulated and delivered by the liposomes. |
| FILED | Monday, April 19, 2010 |
| APPL NO | 12/762794 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/502 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08718671 | Barbeau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida) |
| ABSTRACT | A method of buffering location data on a mobile device. The method transmits location data packets via an unreliable protocol to a receiving device and buffers a copy of the location data packet. Periodically, the method also transmits a location data packet via a reliable protocol to the receiving device. When no acknowledgement is received from the receiving device, the location data sent via the reliable protocol is buffered to memory. Once an acknowledgement is received from the receiving device, all of the buffered location data is sent to the receiving device via an unreliable protocol. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/082722 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/456.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08716029 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steve S. Kim (Dayton, Ohio); Zhifeng Kuang (Beavercreek, Ohio); Rajesh R. Naik (Dayton, Ohio); Barry L. Farmer (Xenia, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the United States (Washington, District of Columbia) |
| INVENTOR(S) | Steve S. Kim (Dayton, Ohio); Zhifeng Kuang (Beavercreek, Ohio); Rajesh R. Naik (Dayton, Ohio); Barry L. Farmer (Xenia, Ohio) |
| ABSTRACT | A biosensor that utilizes carbon nanotubes functionalized with a protein sequence. One domain of the multifunctional peptide sequence noncovalently binds to the surface of single-walled carbon nanotubes (SWNTs), while a second domain of the sequence recognizes and binds to a target molecule. The sequence of the peptide may be tailored to allow it to recognize and bind to specific target molecules, such as chemicals, biological materials, and explosives. The binding of the target molecule to the peptide may alter a material property of the SWNTs. |
| FILED | Monday, September 19, 2011 |
| APPL NO | 13/235561 |
| ART UNIT | 1677 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/501 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717108 | Rosadiuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul G. Rosadiuk (Gardena, California); Walid M. Al-Bondak (Los Angeles, California); Bruce A. Igawa (Trabuco Canyon, California); Bryce Smith (Los Angeles, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Paul G. Rosadiuk (Gardena, California); Walid M. Al-Bondak (Los Angeles, California); Bruce A. Igawa (Trabuco Canyon, California); Bryce Smith (Los Angeles, California) |
| ABSTRACT | A coaxial resonator device includes a substrate including a chip-and-wire circuit. A resonator is coupled to the substrate using a conductive epoxy. A system includes a resonator device. The resonator device includes a housing having one or more connectors, a resonator coupled to the housing a conductive epoxy, and a chip-and-wire circuit connecting the resonator to the one or more connectors. |
| FILED | Tuesday, April 12, 2011 |
| APPL NO | 13/085448 |
| ART UNIT | 2843 — Printing/Measuring and Testing |
| CURRENT CPC | Oscillators 331/68 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08717666 | Nguyen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Quant-Viet Nguyen (Richmond Heights, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Quant-Viet Nguyen (Richmond Heights, Ohio) |
| ABSTRACT | A compact source of polarization-entangled photons includes a laser source, producing a laser beam, a pair of nonlinear crystals, in optical contact with each other, with one of the pair of nonlinear crystals having an input face, with the laser beam incident on the input face, and another of the pair of nonlinear crystals rotated 90°, along an axis perpendicular to the input face, with respect to each other and a fiber coupling point, configured to receive a pair of single-mode fibers. Pairs of polarization-entangled photons are produced through spontaneous parametric down conversion of the laser beam and provided to the fiber coupling point. |
| FILED | Monday, May 23, 2011 |
| APPL NO | 13/113458 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Optical: Systems and elements 359/330 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 06, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140506.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page