FedInvent™ Patents

Patent Details for Tuesday, June 03, 2014

This page was updated on Monday, March 27, 2023 at 04:00 AM GMT

Department of Health and Human Services (HHS)

08740762 — Specific inhibition of cPLA₂enhances the efficacy of radiotherapy

US 08740762	Hallahan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Dennis E. Hallahan (Nashville, Tennessee); Eugenia M. Yazlovitskaya (Nolensville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	Dennis E. Hallahan (Nashville, Tennessee); Eugenia M. Yazlovitskaya (Nolensville, Tennessee)
ABSTRACT	A method for increasing the radiosensitivity of a target tissue in a subject is disclosed. In some embodiments, the methods includes administering a cytosolic phospholipase A2 (cPLA₂) antagonist to the subject, whereby the radiosensitivity of the target tissue is increased. Also disclosed are methods for suppressing tumor growth in a subject and methods for inhibiting tumor blood vessel growth.
FILED	Monday, April 07, 2008
APPL NO	12/098796
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/3
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08740826 — Musculoskeletal loading device

US 08740826	Leismer
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Jeffrey M. Leismer (Sheboygan, Wisconsin)
ASSIGNEE(S)
INVENTOR(S)	Jeffrey M. Leismer (Sheboygan, Wisconsin)
ABSTRACT	A device for non-invasively mechanically stimulating bone or muscle includes a vibrational energy generator for applying vibrational energy to a first end of a length of a tissue which includes bone and/or muscle. The vibrational energy is for inducing strain in at least one region within the length of tissue. A restraint is disposed opposite the first end of the length to resist translation of the length during operation of the device and to provide loading to the bone or muscle. A connecting structure couples the restraint to the vibrational energy generator. The device does not require gravity to operate and as a result is expected to have applications in space, such as with astronauts, with those having bone aliments such as bed-ridden patients, persons with osteoporosis or disuse atrophy, athletes, recovering bone cancer patients, and persons with musculoskeletal disorders.
FILED	Tuesday, February 16, 2010
APPL NO	12/658903
ART UNIT	3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC	Surgery: Kinesitherapy 61/49
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08740835 — Treatment of vascular occlusions using ultrasonic energy and microbubbles

US 08740835	Soltani et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Azita Soltani (Snohomish, Washington); Douglas R. Hansmann (Bainbridge Island, Washington)
ASSIGNEE(S)	Ekos Corporation (Bothell, Washington)
INVENTOR(S)	Azita Soltani (Snohomish, Washington); Douglas R. Hansmann (Bainbridge Island, Washington)
ABSTRACT	In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble-therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase.
FILED	Thursday, February 17, 2011
APPL NO	13/029962
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery 64/22
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08741277 — Soft tissue and bone augmentation and bulking utilizing muscle-derived progenitor cells, compositions and treatments thereof

US 08741277	Chancellor et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Michael B. Chancellor (Pittsburg, Pennsylvania); Johnny Huard (Pittsburgh, Pennsylvania); Christopher C. Capelli (Kenosha, Wisconsin); Zhuqing Qu (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Michael B. Chancellor (Pittsburg, Pennsylvania); Johnny Huard (Pittsburgh, Pennsylvania); Christopher C. Capelli (Kenosha, Wisconsin); Zhuqing Qu (Pittsburgh, Pennsylvania)
ABSTRACT	The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for dermatological conditions, gastroesophageal reflux, vesico-ureteral reflux, urinary incontinence, fecal incontinence, heart failure, and myocardial infarction.
FILED	Thursday, August 17, 2006
APPL NO	11/505735
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/93.100
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08741307 — Hybrid prokaryotic-eukaryotic tubulins and use thereof

US 08741307	Kull et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	F. Jon Kull (Enfield, New Hampshire); Jared C. Cochran (Bloomington, Indiana)
ASSIGNEE(S)	Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S)	F. Jon Kull (Enfield, New Hampshire); Jared C. Cochran (Bloomington, Indiana)
ABSTRACT	The present invention embraces hybrid Prosthecobacter-eukaryotic tubulin proteins and use thereof for identifying agents that modulate the activity of tubulin.
FILED	Monday, April 19, 2010
APPL NO	13/266582
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/192.100
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08741310 — Fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies

US 08741310	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Bing Chen (Chestnut Hill, Massachusetts); Gary H. Frey (Nashua, New Hampshire); Stephen C. Harrison (Brighton, Massachusetts)
ASSIGNEE(S)	Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Howard Hughes Medical Institute (Chevy Chase, Maryland)
INVENTOR(S)	Bing Chen (Chestnut Hill, Massachusetts); Gary H. Frey (Nashua, New Hampshire); Stephen C. Harrison (Brighton, Massachusetts)
ABSTRACT	Isolated, antigenic polypeptides including a prehairpin intermediate conformation of gp41 and vectors encoding such polypeptides are provided. Antibodies that bind to a prehairpin intermediate conformation of gp41 and methods of making antibodies a that bind to prehairpin intermediate conformation of gp41 are also provided. Vaccines against a prehairpin intermediate conformation of gp41, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided. Methods of screening compounds that bind to an isolated, prehairpin intermediate conformation of gp41 are further provided.
FILED	Friday, August 27, 2010
APPL NO	12/869967
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/208.100
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08741313 — Polypeptide vaccine and vaccination strategy against mycobacterium

US 08741313	Sable et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Suraj Sable (Atlanta, Georgia); Bonnie B. Plikaytis (Atlanta, Georgia); Thomas M. Shinnick (Atlanta, Georgia); Rama Rao Amara (Decatur, Georgia); Manl Cheruvu (Savannah, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Suraj Sable (Atlanta, Georgia); Bonnie B. Plikaytis (Atlanta, Georgia); Thomas M. Shinnick (Atlanta, Georgia); Rama Rao Amara (Decatur, Georgia); Manl Cheruvu (Savannah, Georgia)
ABSTRACT	A vaccine is provided wherein a polypeptide or combination of peptides from M. tuberculosis is administered to a subject to elicit an immune response. The polypeptide vaccine is administered as part of a prime-boost strategy with BCG vaccine to increase the immunoprotection in a subject such that prevention or elimination of disease is achieved. Finally, a pharmaceutical package is provided that encompasses a polypeptide vaccine for M. tuberculosis that when administered to a subject elicits immunoprotection.
FILED	Monday, January 12, 2009
APPL NO	12/812541
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/248.100
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08741317 — Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery

US 08741317	Uhrich et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Kathryn E. Uhrich (New Brunswick, New Jersey); Roselin Rosario-Meléndez (New Brunswick, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Kathryn E. Uhrich (New Brunswick, New Jersey); Roselin Rosario-Meléndez (New Brunswick, New Jersey)
ABSTRACT	The invention provides polymers and methods for their use. Specifically, certain embodiments of the present invention provide a polymer that comprises a plurality of salicylic acid-adipic (SA-Adipic) units of the following formula and a plurality of salicylic acid-diethylmalonic (SA-DEM) units of the following formula Certain embodiments of the invention also provide slow degrading microspheres comprising polymers described herein for undelayed and sustained drug delivery. Certain embodiments of the present invention provide methods for treating a chronic eye disease or arthritis in a patient, comprising administering to the patient a therapeutically effective amount of a polymer or microsphere as described herein.
FILED	Friday, August 19, 2011
APPL NO	13/213843
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/185 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 67/04 (20130101)
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08741561 — Gene sets for detection of ultraviolet A exposure and methods of use thereof

US 08741561	Terunuma et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Atsushi Terunuma (Rockville, Maryland); Elizabeth Falloon (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Atsushi Terunuma (Rockville, Maryland); Jonathan Vogel (Bethesda, Maryland)
ABSTRACT	Ultraviolet radiation (UVR) has profound effects on human skin. However, its effects on the global transcriptome in vivo have not been well characterized. In addition, the contribution of the UVA component of UVR has not been previously assessed in vivo. Disclosed herein is the identification of sets of genes that are either up-regulated or down-regulated in response to UVA exposure. The gene sets described herein can be used to accurately identify skin samples that have been exposed to UVA and to assess the ability of a sun protection product to block the effects of UVA.
FILED	Thursday, February 24, 2011
APPL NO	13/580832
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
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08741564 — Quantitative nuclease protection assay (QNPA) and sequencing (QNPS) improvements

US 08741564	Seligmann et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Bruce Seligmann (Tucson, Arizona); Debrah Thompson (Tucson, Arizona); Tom Vasicek (Minneapolis, Minnesota); Debra A. Gordon (Tucson, Arizona)
ASSIGNEE(S)	HTG Molecular Diagnostics, Inc. (Tucson, Arizona)
INVENTOR(S)	Bruce Seligmann (Tucson, Arizona); Debrah Thompson (Tucson, Arizona); Tom Vasicek (Minneapolis, Minnesota); Debra A. Gordon (Tucson, Arizona)
ABSTRACT	The present disclosure provides an improvement to quantitative Nuclease Protection Assay (qNPA) and quantitative Nuclease Protection Sequencing (qNPS) methods. The disclosed methods use nuclease protection probes (NPPs) that include 5′-end and/or 3-end flanking sequences, which provide a universal hybridization and/or amplification sequence. The disclosed methods can be used to sequence or detect target nucleic acid molecules, such as those present in fixed or insoluble samples.
FILED	Thursday, April 26, 2012
APPL NO	14/115032
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.100
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08741567 — Composition and methods related to modification of 5-hydroxymethylcytosine (5-hmC)

US 08741567	He et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Chuan He (Chicago, Illinois); Chunxiao Song (Chicago, Illinois)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois)
INVENTOR(S)	Chuan He (Chicago, Illinois); Chunxiao Song (Chicago, Illinois)
ABSTRACT	The present invention relates generally to the field of molecular biology. More particularly, it concerns methods and compositions for detecting, evaluating, and/or mapping 5-hydroxymethyl-modified cytosine bases within a nucleic acid molecule.
FILED	Wednesday, April 27, 2011
APPL NO	13/095505
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.110
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08741573 — Consensus coding sequences of human breast and colorectal cancers

US 08741573	Sjoblom et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Center for Research Resources (NCRR)
APPLICANT(S)	Tobias Sjoblom (Baltimore, Maryland); Sian Jones (Baltimore, Maryland); D. Williams Parsons (Baltimore, Maryland); Laura D. Wood (Baltimore, Maryland); Jimmy Lin (Baltimore, Maryland); Thomas Barber (Baltimore, Maryland); Diana Mandelker (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Victor E. Velculesu (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Tobias Sjoblom (Baltimore, Maryland); Sian Jones (Baltimore, Maryland); D. Williams Parsons (Baltimore, Maryland); Laura D. Wood (Baltimore, Maryland); Jimmy Lin (Baltimore, Maryland); Thomas Barber (Baltimore, Maryland); Diana Mandelker (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Victor E. Velculesu (Baltimore, Maryland)
ABSTRACT	Analysis of 13,023 genes in 11 breast and 11 colorectal cancers revealed that individual tumors accumulate an average of ˜90 mutant genes but that only a subset of these contribute to the neoplastic process. Using stringent criteria to delineate this subset, we identified 189 genes (average of 11 per tumor) that were mutated at significant frequency. The vast majority of these genes were not known to be genetically altered in tumors and are predicted to affect a wide range of cellular functions, including transcription, adhesion, and invasion. These data define the genetic landscape of two human cancer types, provide new targets for diagnostic and therapeutic intervention and monitoring.
FILED	Monday, August 13, 2007
APPL NO	12/377073
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.140
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08741574 — Gene expression signature of genomic instability in breast cancer

US 08741574	Ried et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Karl Thomas Ried (Bethesda, Maryland); Jens Habermann (Celle, Germany); Nancy Lan Guo (Morgantown, West Virginia); Gert Auer (Solna, Sweden)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); West Virginia University Research Corporation (Morgantown, West Virginia)
INVENTOR(S)	Karl Thomas Ried (Bethesda, Maryland); Jens Habermann (Celle, Germany); Nancy Lan Guo (Morgantown, West Virginia); Gert Auer (Solna, Sweden)
ABSTRACT	Methods of assessing genomic instability in breast cancer tissue by measuring the expression level of genes CDKN2A, SCYA18, STK15, NXF1, cDNA Dkfzp762M127, p28 KIAA0882, MYB, Human clone 23948, RERG, HNF3A, and ACADSB or a nucleic acid sequence comprising about 90% or greater sequence identity to SEQ ID NO: 21 in breast cancer tissue, an array suitable for use in such methods, and related methods and compositions.
FILED	Tuesday, September 15, 2009
APPL NO	13/119101
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.140
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08741584 — Follistatin-like protein-1 as a biomarker for inflammatory disorders

US 08741584	Hirsch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S)	Raphael Hirsch (Pittsburgh, Pennsylvania); David C. Wilson (Monroeville, Pennsylvania)
ABSTRACT	The present invention relates to methods and compositions for diagnosis of inflammatory disorders, and in non-limiting embodiments, of inflammatory disorders associated with elevated interleukin-1β (“IL-1β”), based on increased levels of follistatin-like protein 1 (“FSTL-1”). In particular non-limiting embodiments, the invention further provides for methods of identifying subjects with systemic onset juvenile idiopathic arthritis (“SOJIA”) who are at increased risk for developing macrophage activation syndrome (“MAS”) comprising detecting, in said subjects, hyper-increased levels of FSTL-1. In additional non-limiting embodiments, the invention provides for methods of identifying subjects with Kawasaki disease who are at increased risk of developing aortic aneurysms comprising detecting, in said subjects, hyper-increased levels of FSTL-1.
FILED	Monday, February 04, 2013
APPL NO	13/758405
ART UNIT	1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/7.100
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08741590 — Subcutaneous glucose electrode

US 08741590	Heller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Adam Heller (Austin, Texas); Michael V. Pishko (Austin, Texas)
ASSIGNEE(S)	Abbott Diabetes Care Inc. (Alameda, California)
INVENTOR(S)	Adam Heller (Austin, Texas); Michael V. Pishko (Austin, Texas)
ABSTRACT	A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode is preferably three or four-layered, with the layers serially deposited within a recess upon the tip of a polyamide insulated gold wire. A first glucose concentration-to-current transducing layer is overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited (third layer). An outer (fourth) layer is biocompatible.
FILED	Tuesday, April 03, 2007
APPL NO	11/695612
ART UNIT	1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/14
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08741591 — pH-insensitive glucose indicator protein

US 08741591	Ye et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Kaiming Ye (Fayetteville, Arkansas); Sha Jin (Fayetteville, Arkansas)
ASSIGNEE(S)	The Research Foundation for The State University of New York (Binghamton, New York)
INVENTOR(S)	Kaiming Ye (Fayetteville, Arkansas); Sha Jin (Fayetteville, Arkansas)
ABSTRACT	The present invention encompasses a glucose indicator protein, a biosensor comprising one or more glucose indicator proteins, and methods of use thereof.
FILED	Tuesday, October 12, 2010
APPL NO	12/902725
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/14
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08741592 — Methods of screening an agent for an activity in an isolated eye of a teleost

US 08741592	McGrath et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Phylonix Pharmaceuticals, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	Phylonix Pharmaceuticals, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Patricia McGrath (Cambridge, Massachusetts); Wen Lin Seng (Westborough, Massachusetts)
ABSTRACT	The present invention provides methods of screening an agent for an activity in an isolated organ, e.g., eye, from a teleost, e.g., zebrafish. Methods of isolating eyes from zebrafish are provided. Methods of screening an agent for an ocular activity in the isolated eye are provided. Methods of screening an agent for an ocular activity in a model of ocular disease or disorder are provided. Methods of screening an agent for an ocular activity in the isolated eye and for screening the agent for cell death and/or toxic activity in the eye or other organ or tissue are provided. The invention further provides high throughput methods of screening agents for an activity in isolated eyes of zebrafish in multi-well plates.
FILED	Friday, January 04, 2013
APPL NO	13/734271
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/18
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08741649 — Methods for enhancing genome stability and telomere elongation in embryonic stem cells

US 08741649	Ko et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Minoru S. H. Ko (Cockeysville, Maryland); Michal Zalzman (Baltimore, Maryland); Lioudmila V. Sharova (Pasadena, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S)	Minoru S. H. Ko (Cockeysville, Maryland); Michal Zalzman (Baltimore, Maryland); Lioudmila V. Sharova (Pasadena, Maryland)
ABSTRACT	The disclosure provides methods for increasing genome stability of an embryonic stem (ES) cell or induced pluripotent stem (iPS) cell, increasing telomere length in an ES or iPS cell, or both, for example by contacting an ES or iPS cell with an agent that increases expression of Zscan4 in the cell. Methods for increasing the genome stability in a population of ES or iPS cells, increasing telomere length in a population of ES or iPS cells, or both, are provided, for example by selecting Zscan4⁺ ES or iPS cells from the population of ES or iPS cells (which can include both Zscan4⁺ and Zscan4⁻ES or iPS cells). Therapeutic methods of using ES or iPS cells expressing Zscan4 are also provided. Further provided are methods of treating cancer by administering a Zscan4 polynucleotide or Zscan4 polypeptide. Also provided are methods of inducing differentiation of isolated ES or iPS cells into germ cells.
FILED	Thursday, September 02, 2010
APPL NO	13/393456
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/00 (20130101) C12N 5/0606 (20130101) Original (OR) Class C12N 15/00 (20130101)
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08741658 — Rapid method to measure cyanide in biological samples

US 08741658	Boss et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Gerry Boss (La Jolla, California); Vijay Sharma (La Jolla, California); Matthew Brenner (Irvine, California); Purnendu K. Dasgupta (Arlington, Texas); William Curt Blackledge (Carlsbad, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California); Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Gerry Boss (La Jolla, California); Vijay Sharma (La Jolla, California); Matthew Brenner (Irvine, California); Purnendu K. Dasgupta (Arlington, Texas); William Curt Blackledge (Carlsbad, California)
ABSTRACT	A method and devices analyze for the presence of cyanide in samples using colorimetric analysis of samples after contacting with cobinamide or monocyanocohinapmide.
FILED	Tuesday, March 15, 2011
APPL NO	13/634703
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/109
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08741662 — Albumin-bound protein/peptide complex as a biomarker for disease

US 08741662	Van Eyk et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Jennifer E. Van Eyk (Baltimore, Maryland); Rebekah Lynn Gundry (Baltimore, Maryland); Robert J. Cotter (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkin University (Baltimore, Maryland)
INVENTOR(S)	Jennifer E. Van Eyk (Baltimore, Maryland); Rebekah Lynn Gundry (Baltimore, Maryland); Robert J. Cotter (Baltimore, Maryland)
ABSTRACT	Methods and kits for diagnosis and prognosis using biomarkers comprising albumin-bound protein/peptide complex (ABPPC).
FILED	Thursday, June 14, 2007
APPL NO	12/304895
ART UNIT	1678 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/506
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08741663 — Enhanced detection sensitivity with piezoelectric sensors

US 08741663	Shih et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) U.S. State Government Commonwealth of Pennsylvania
APPLICANT(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (San Jose, California)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (San Jose, California)
ABSTRACT	A method for enhancing the detection sensitivity of a piezoelectric microcantilever sensor. The method may involve providing a piezoelectric microcantilever and inducing a change in the Young's modulus during detection of a species of interest. The change in the Young's modulus may be induced or enhanced by the application of a DC bias electric field to the piezoelectric layer that enhances non-180° polarization domain switching of the piezoelectric layer. The change in the Young's modulus may also result from binding of the species of interest to the piezoelectric microcantilever sensor or a combination of binding and application of a DC bias electric field Significantly enhanced detection sensitivity results from the changed Young's modulus of the piezoelectric layer.
FILED	Wednesday, March 04, 2009
APPL NO	12/921756
ART UNIT	1677 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/524
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08741832 — Pegylated albumin and uses thereof

US 08741832	Acharya et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Seetharama A. Acharya (Cresskill, New Jersey); Belur N. Manjula (Cresskill, New Jersey)
ASSIGNEE(S)	Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S)	Seetharama A. Acharya (Cresskill, New Jersey); Belur N. Manjula (Cresskill, New Jersey)
ABSTRACT	The present invention provides PEGylated hemoglobins and PEGylated albumins comprising polyethylene glycol (PEG) conjugated to hemoglobin or to albumin, wherein the PEG is a maleimide PEG, an alkylamide PEG, an iodoacetamide PEG, a p-nitro thio-phenyl PEG, a vinyl sulfone PEG, or a mixed disulfide PEG; and PEGylated albumins and PEGylated hemoglobins comprising polyethylene glycol (PEG) attached to a thiolated amino group of albumin or hemoglobin, wherein the amino group is thiolated using dithio sulfo succinimidyl propionate (DTSSP) or dithiosuccinimidyl propionate (DTSP) or dithiobispropionimidate. The invention also provides methods of preparing PEGylated hemoglobins and PEGylated albumins comprising a) reacting hemoglobin or albumin with a thiolating agent and with a PEGylating agent, and b) capping unPEGylated reactive thiols of hemoglobin or albumin with N-ethyl maleimide.
FILED	Friday, June 09, 2006
APPL NO	11/921064
ART UNIT	1676 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Original (OR) Class Peptides C07K 14/76 (20130101) C07K 14/805 (20130101)
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08741838 — Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors

US 08741838	Toback et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	F. Gary Toback (Chicago, Illinois); Terence E. Martin (Chicago, Illinois); Margaret M. Walsh-Reitz (River Forest, Illinois)
ASSIGNEE(S)	The University of Chicago (Chicago, Illinois)
INVENTOR(S)	F. Gary Toback (Chicago, Illinois); Terence E. Martin (Chicago, Illinois); Margaret M. Walsh-Reitz (River Forest, Illinois)
ABSTRACT	A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease, mucositis, and gastric ulcers.
FILED	Tuesday, March 08, 2011
APPL NO	13/042958
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/7.600
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08741840 — BMP-7 for use in treating neointimal hyperplasia

US 08741840	Hruska et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Keith Hruska (Creve Coeur, Missouri); Eric T. Choi (St. Louis, Missouri)
ASSIGNEE(S)	Washington University (St. Louis, Missouri)
INVENTOR(S)	Keith Hruska (Creve Coeur, Missouri); Eric T. Choi (St. Louis, Missouri)
ABSTRACT	The present invention relates to prevention and treatment of vascular sclerosis, vascular calcification (VC) and neointimal hyperplasia using a morphogen.
FILED	Friday, February 13, 2009
APPL NO	12/867562
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/8.800
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08741842 — Chimeric natriuretic polypeptides with unique pharmacologic profiles

US 08741842	Burnett, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	John C. Burnett, Jr. (Rochester, Minnesota); Candace Y. W. Lee (Saint-Léonard, Canada)
ASSIGNEE(S)	Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S)	John C. Burnett, Jr. (Rochester, Minnesota); Candace Y. W. Lee (Saint-Léonard, Canada)
ABSTRACT	This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.
FILED	Tuesday, June 16, 2009
APPL NO	13/002178
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/12.400
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08741849 — Kinase inhibitors and uses thereof

US 08741849	Panitch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Alyssa Panitch (West Lafayette, Indiana); Brandon Seal (Pleasant Grove, Utah); Brian Ward (Lebanon, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Alyssa Panitch (West Lafayette, Indiana); Brandon Seal (Pleasant Grove, Utah); Brian Ward (Lebanon, Indiana)
ABSTRACT	The present invention relates to kinase inhibiting compositions and uses thereof. The invention further provides isolated kinase inhibiting peptides and uses thereof for inhibiting hyperplasia, for inhibiting the growth of neoplasms, and for inducing programmed cell death in a cell population.
FILED	Thursday, August 07, 2008
APPL NO	12/188109
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/18.900
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08741860 — Modulation of T cell signaling threshold and T cell sensitivity to antigens

US 08741860	Li et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Qi-Jing Li (Mountain View, California); Chang-Zheng Chen (Stanford, California); Mark M. Davis (Atherton, California); Jacqueline Chau (San Jose, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Qi-Jing Li (Mountain View, California); Chang-Zheng Chen (Stanford, California); Mark M. Davis (Atherton, California); Jacqueline Chau (San Jose, California)
ABSTRACT	MicroRNAs (miRNAs) are a diverse and abundant class of ˜22-nucleotide (nt) endogenous regulatory RNAs that play a variety of roles in animal cells by controlling gene expression at the posttranscriptional level. Increased miR-181a expression in mature T cells is shown to cause a marked increase in T cell activation and augments T cell sensitivity to peptide antigens. Moreover, T cell blasts with higher miR-181a expression become reactive to antagonists. The effects of miR-181a on antigen discrimination are in part achieved by dampening the expression of multiple negative regulators in the T cell receptor (TCR) signaling pathway, including PTPN22 and the dual specificity phosphatases DUSP5 and DUSP6. This results in a reduction in the TCR signaling threshold, thus quantitatively and qualitatively enhancing T cell sensitivity to antigens.
FILED	Wednesday, June 02, 2010
APPL NO	12/792585
ART UNIT	1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44
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08741869 — Oligodeoxynucleotide and its use to induce an immune response

US 08741869	Klinman et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Uniformed Services University of the Health Sciences, an institution of higher learning within the Department of Defense (Washington, District of Columbia)
INVENTOR(S)	Dennis M. Klinman (Potomac, Maryland); Ken J. Ishii (Osaka, Japan); Daniela Verthelyi (Potomac, Maryland); James J. Mond (Silver Spring, Maryland)
ABSTRACT	A substantially pure or isolated oligodeoxynucleotide of at least 10 nucleotides is disclosed, wherein the oligodeoxynucleotide comprised a sequence represented by either formula: 5′ N₁N₂N₃T-CpG-WN₄N₅N₆3′ wherein the CpG motif is unmethylated, W is A or T, and N₁, N₂, N₃, N₄, N₅, and N₆are nucleotides, or the formula: 5′ RY-CpG-RY 3′ wherein the central CpG motif is unmethylated, R is A or G, and Y is C or T, as well as an oligodeoxynucleotide delivery complex and a pharmacological composition comprising the present inventive oligodeoxynucleotide, and a method of inducing an immune response by administering the present inventive oligodeoxynucleotide to a host. In some embodiments, the oligodeoxynucleotide includes the nucleic acid sequences set forth as SEQ ID NO: 137.
FILED	Tuesday, February 05, 2013
APPL NO	13/759922
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44.R00
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08741905 — Compounds and methods for treating autoimmune diseases

US 08741905	Wagner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Bridget Wagner (Medford, Massachusetts); Jeremy Duvall (Wakefield, Massachusetts); Danny Hung-Chieh Chou (Cambridge, Massachusetts)
ABSTRACT	The invention relates to a compound of Formula I:
FILED	Monday, May 06, 2013
APPL NO	13/887466
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/255.30
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08741937 — Gamma glutamyl transpeptidase inhibitors and methods of use

US 08741937	Hanigan
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Marie H. Hanigan (Edmond, Oklahoma)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S)	Marie H. Hanigan (Edmond, Oklahoma)
ABSTRACT	Compositions and methods for inhibiting human gamma-glutamyl transpeptidase (GGT) in vivo or in vitro and for inhibiting and killing neoplastic cancer cells, for example for the treatment, inhibition or prevention of tumors or malignant growths or other neoplasias in mammals, or sensitizing tumor to other therapies including radiation therapy. The GGT inhibitor compounds comprise a class of benzylthiadiazol benzenesulfoniamides. The compounds may also be used to treat a reversible airways obstruction in a mammal or a disease associated with reverse airways obstruction such as asthma, chronic obstructive pulmonary disease (COPD), allergic reaction, respiratory tract infection or upper respiratory tract disease. Other diseases or conditions which may be treated include, for example, degenerative diseases, renal diseases, liver diseases, cardiovascular disease and inner ear conditions or diseases.
FILED	Friday, March 23, 2012
APPL NO	13/428224
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/363
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08741942 — Inhibitors of cellular necrosis

US 08741942	Cuny et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Gregory D. Cuny (Somerville, Massachusetts); Prakash Jagtap (North Andover, Massachusetts); Junying Yuan (Newton, Massachusetts); Alexei Degterev (Brookline, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Gregory D. Cuny (Somerville, Massachusetts); Prakash Jagtap (North Andover, Massachusetts); Junying Yuan (Newton, Massachusetts); Alexei Degterev (Brookline, Massachusetts)
ABSTRACT	The present invention relates to compounds and pharmaceutical preparations and their use in therapy for preventing or treating trauma, ischemia, stroke and degenerative diseases associated with cell death. Methods and compositions of the invention are particularly useful for treating neurological disorders associated with cellular necrosis.
FILED	Tuesday, February 21, 2012
APPL NO	13/401561
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/397
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08741944 — Anti-infective agents against intracellular pathogens

US 08741944	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Ohio State University Research Foundation (Columbus, Ohio)
ASSIGNEE(S)	The Ohio State University Research Foundation (Columbus, Ohio)
INVENTOR(S)	Ching-Shih Chen (Upper Arlington, Ohio); Hao-Chieh Chiu (Columbus, Ohio); Dasheng Wang (Dublin, Ohio)
ABSTRACT	A new class of phosphoinositide-dependent kinase-1 (PDK-1) inhibitors of Formula I: wherein X wherein X is —CF₃, Ar is selected from and R is selected from where R′ is L-Lys, D-Lys, β-Ala, L-Lue, L-Ile, Phe, SO₂CH₂CH₂NH₂, SO₂NH₂, Asn, Glu or Gyl, and R″ is methyl, ethyl, allyl, CH₂CH₂OH, CH₂CN, CH₂CH₂CN, CH₂CONH₂,
FILED	Wednesday, April 24, 2013
APPL NO	13/869386
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/406
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08741947 — Biologically active macrolides, compositions, and uses thereof

US 08741947	Boyd et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Michael R. Boyd (Mobile, Alabama); Kirk R. Gustafson (Frederick, Maryland); Charles L. Cantrell (Longmont, Colorado)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Michael R. Boyd (Mobile, Alabama); Kirk R. Gustafson (Frederick, Maryland); Charles L. Cantrell (Longmont, Colorado)
ABSTRACT	The present invention provides a compound of the formula (I) or (II, wherein R¹is H, alkyl, alkenyl or aryl, R²is H, alkyl or aryl, R³is H, a alkyl, alkenyl or aryl, R⁴and R⁴-R⁸are independently R¹⁰, C(O)R¹⁰or SO₂R¹⁰, wherein R¹⁰is H, alkyl, alkenyl or aryl, and R⁹is R^9a, C(O)R^9aor SO₂R^9a, wherein R^9ais H, alkyl, alkenyl or aryl. R^9acan be unsubstituted or substituted with one or more oxo(═O), OR^9b, OC(O)R^9b, OSO₂R^9b, NHR^9b, NHC(O)R^9band NHSO₂R^9bgroups. R^9bis H, alkyl, alkenyl, or aryl. R^9bcan be unsubstituted or substituted with one or more groups such as oxo(═O), OR^9c, CO₂R^9c, CO₂R^9cand OC(O)R^9c. R^9cis H, or a unsubstituted or substituted alkyl, alkenyl or aryl. The present invention further provides a composition comprising at least one compound of the present invention and a pharmaceutically acceptable carrier, alone or in combination with at least one additional active agent. The present invention further provides a method of treating a condition treatable by the inhibition of vacuolar-type (H+)-ATPase and a method of treating cancer.
FILED	Friday, August 06, 2010
APPL NO	12/851691
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/449
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08741967 — Use of unsaturated sphingosine compounds as chemotherapeutic agents for the treatment of cancer

US 08741967	Saba et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Julie D. Saba (Oakland, California); Henrik Fyrst (Oakland, California); Robert Bittman (Roslyn Heights, New York)
ASSIGNEE(S)	Children's Hospital and Research Center at Oakland (Oakland, California); Research Foundation of the City University of New York (New York, New York)
INVENTOR(S)	Julie D. Saba (Oakland, California); Henrik Fyrst (Oakland, California); Robert Bittman (Roslyn Heights, New York)
ABSTRACT	The present invention is directed to unsaturated sphingosine compounds which are useful as therapeutic agents for the treatment of cancer and for the treatment of other diseases including diabetes and infection with intracellular bacteria. This invention is also directed to methods of using the compounds and pharmaceutical compositions comprising the compounds in treating these diseases.
FILED	Friday, December 12, 2008
APPL NO	12/747253
ART UNIT	1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 8/68 (20130101) Original (OR) Class A61K 31/133 (20130101)
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08742069 — Concentrated aqueous silk fibroin solution and use thereof

US 08742069	Kaplan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Dental and Craniofacial Research (NIDCR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea)
ABSTRACT	The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
FILED	Thursday, March 14, 2013
APPL NO	13/827304
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300
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08742084 — Bioreactive agents

US 08742084	Rothschild et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Kenneth J. Rothschild (Newton, Massachusetts); Sanjay M. Sonar (Thane, India); Jerzy Olejnik (Brookline, Massachusetts)
ASSIGNEE(S)	The Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	Kenneth J. Rothschild (Newton, Massachusetts); Sanjay M. Sonar (Thane, India); Jerzy Olejnik (Brookline, Massachusetts)
ABSTRACT	This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. The invention also relates to targets isolated with conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. The invention further relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and individual substances in a complex background of substances.
FILED	Friday, September 14, 2012
APPL NO	13/616499
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/23.100
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08742092 — RNA sequence-specific mediators of RNA interference

US 08742092	Tuschl et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Thomas Tuschl (Brooklyn, New York); Phillip A. Sharp (Newton, Massachusetts); Phillip D. Zamore (Northborough, Massachusetts); David P. Bartel (Brookline, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V. (Munich, Germany)
INVENTOR(S)	Thomas Tuschl (Brooklyn, New York); Phillip A. Sharp (Newton, Massachusetts); Phillip D. Zamore (Northborough, Massachusetts); David P. Bartel (Brookline, Massachusetts)
ABSTRACT	The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications.
FILED	Monday, October 04, 2010
APPL NO	12/897756
ART UNIT	1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/24.500
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08742141 — Inhibition and treatment of prostate cancer metastasis

US 08742141	Bergan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Raymond C. Bergan (Chicago, Illinois); Karl A. Scheidt (Evanston, Illinois)
ABSTRACT	The present invention provides compounds and methods of inhibiting and treating metastatic prostate cancer. The compounds include MEK4 inhibitors. In another aspect the invention provides methods of identifying inhibitors of metastatic prostate cancer by screening for inhibitors of MEK4.
FILED	Monday, July 01, 2013
APPL NO	13/932300
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Organic compounds 549/403
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08742333 — Method to perform beam-type collision-activated dissociation in the pre-existing ion injection pathway of a mass spectrometer

US 08742333	Coon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Joshua J. Coon (Middleton, Wisconsin); Graeme C. McAlister (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Joshua J. Coon (Middleton, Wisconsin); Graeme C. McAlister (Madison, Wisconsin)
ABSTRACT	Described herein are methods and systems related to the use of the pre-existing ion injection pathway of a mass spectrometer to perform beam-type collision-activated dissociation, as well as other dissociation methods. Following injection and selection of a particular ion type or population, that population can be fragmented using the pre-existing ion injection pathway or inlet of a mass spectrometer. This is achieved by transmitting the ions back along the ion injection pathway. As the ions pass into the higher pressure regions located in or near the atmospheric pressure inlet, the ions are fragmented and then trapped. Following fragmentation and trapping, the ions can either be re-injected into the primary ion selection device or sent on to a secondary mass analyzer.
FILED	Friday, September 16, 2011
APPL NO	13/234398
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/282
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08742754 — Method and system for diffusion tensor imaging

US 08742754	Hasan
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Khader M. Hasan (Houston, Texas)
ASSIGNEE(S)	Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S)	Khader M. Hasan (Houston, Texas)
ABSTRACT	Methods and systems for displaying microstructural integrity and/or connectivity of a region of interest (ROI) in a patient are disclosed. Methods and systems for tissue segmentation and atlas-based tissue segmentation in ROI of a patient using diffusion MRI data are also described. A method for studying microstructural integrity and/or connectivity of a region of interest (ROI) in a patient includes acquiring, via an imaging system, diffusion magnetic resonance (MRI) data in the ROI by using an Icosahedral Diffusion Tensor Encoding Scheme (IDTES); computing, via the imaging system, mean diffusivity (MD) and fractional anisotropy (FA) by using logarithm-moment algorithm (LMA); and displaying, on a display, the microstructural integrity and/or connectivity of ROI based on the computed MD and FA. The diffusion MRI data includes diffusion-weighted imaging (DWI) data or diffusion tensor imaging (DTI) data. In some cases, displaying the microstructural integrity and/or connectivity of ROI takes place in real time.
FILED	Wednesday, February 16, 2011
APPL NO	13/028286
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/307
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08744155 — Imaging or communications system utilizing multisample apodization and method

US 08744155	Walker et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	William F. Walker (Barboursville, Virginia); Drake A. Guenther (Annapolis, Maryland); Kevin Owen (Crozet, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	William F. Walker (Barboursville, Virginia); Drake A. Guenther (Annapolis, Maryland); Kevin Owen (Crozet, Virginia)
ABSTRACT	Methods, systems and system components for optimizing contrast resolution of an imaging or sensing system utilizing multiple channels of broadband data associated with an array of transducers. Channels or data are filtered by passing the channels of data through finite impulse response (FIR) filters on each channel. The filters each have multiple taps having tap weights pre-calculated as a function of distance of the array from an object that energy is being transmitted to or reflected from. The weights are pre-computed through a deterministic equation based on an a priori system model.
FILED	Monday, February 16, 2009
APPL NO	12/371911
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/131
VIEW PATENT	@ USPTO: Full Text PDF

08744164 — Automated analysis of images using bright field microscopy

US 08744164	Ozinsky et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Adrian Ozinsky (Seattle, Washington); Jyrki Juhani Selinummi (Nokia, Finland); Ilya Shmulevich (Seattle, Washington); Pekka Ruusuvuori (Pori, Finland)
ASSIGNEE(S)	Institute for Systems Biology (Seattle, Washington)
INVENTOR(S)	Adrian Ozinsky (Seattle, Washington); Jyrki Juhani Selinummi (Nokia, Finland); Ilya Shmulevich (Seattle, Washington); Pekka Ruusuvuori (Pori, Finland)
ABSTRACT	A system and method for automatically observing and counting cells without using a stain or a fluorescent material. The system includes an optical microscope having a sensor that provides an electrical signal representative of a field of view. The microscope is motorized so as to allow automatic change of focus. A sample containing cells to be analyzed is provided. No stain or fluorescent substance is used. When the microscope is operated in a deliberately out-of-focus condition, cells appear to have either a bright or a dark spot that can be used to report the number of cells in the sample. The intensity variation detected in images acquired in different focal planes is used to identify cell shapes using image analysis software such as CellProfiler. A result is reported in any convenient format, such as a false color image.
FILED	Monday, April 04, 2011
APPL NO	13/079776
ART UNIT	2487 — Recording and Compression
CURRENT CPC	Image analysis 382/133
VIEW PATENT	@ USPTO: Full Text PDF

08744571 — Method and system for the prediction of cardiac arrhythmias, myocardial ischemia, and other diseased condition of the heart associated with elevated sympathetic neural discharges

US 08744571	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Peng-Sheng Chen (Indianapolis, Indiana); Shengmei Zhou (Los Angeles, California)
ASSIGNEE(S)	Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S)	Peng-Sheng Chen (Indianapolis, Indiana); Shengmei Zhou (Los Angeles, California)
ABSTRACT	Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia, myocardial ischemia, congestive heart failure and other diseased conditions of the heart associated with elevated sympathetic neural discharges in a patient. The methods and systems comprise monitoring the sympathetic neural discharges of a patient from the stellate ganglia, the thoracic ganglia, or both, and detecting increases in the sympathetic neural discharges. The methods and systems may further comprise delivering therapy to the patient in response to a detected increase in the sympathetic neural discharge, such as delivering one or more pharmacological agents; stimulating myocardial hyperinnervation in the sinus node and right ventricle of the heart of the patient; and applying cardiac pacing, cardioversion or defibrillation shocks. Pharmacologic agents which may be used in connection with the delivery of include those which are known to exert anti-arrhythmic effect and anti-convulsant agents, such as phenytoin, carbamazepine, valproate, and phenobarbitone. Other pharmacologic agents may be used to treat impending myocardial ischemia and other diseased conditions of the heart associated with elevated sympathetic neural discharges.
FILED	Tuesday, April 06, 2010
APPL NO	12/755139
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/3
VIEW PATENT	@ USPTO: Full Text PDF

08744601 — Methods for optimization of biventricular pacing devices and systems useful therefor

US 08744601	Spotnitz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Henry M Spotnitz (New York, New York); Thomas A Quinn (Broomfield, Colorado); George Berberian (Merrillville, Indiana)
ASSIGNEE(S)	Medtronic, Inc. (Minneapolis, Minnesota)
INVENTOR(S)	Henry M Spotnitz (New York, New York); Thomas A Quinn (Broomfield, Colorado); George Berberian (Merrillville, Indiana)
ABSTRACT	The invention is directed to methods and devices for optimization of biventricular pacing in subjects suffering from heart failure. The invention provides for a method for selection of optimal parameters for permanent pacing, the method comprising: positioning one or more arrays of lead wires in the posterior pericardium of a subject, wherein the arrays are connected to a multiplexing switch, wherein the switch is connected to a computer processor and a biventricular pacemaker; from the computer processor, generating a randomized sequence of: (i) pacing sites (VPS), (ii) right ventricular-left ventricular delays (RLDs), (iii) heart rates (HR); (iv) atrioventricular delays (AVDs), (v) or any combination or permutation thereof; and determining cardiac output in real time, using aortic flow velocity, thereby allowing selection of optimal parameters for permanent pacing.
FILED	Tuesday, April 04, 2006
APPL NO	11/910532
ART UNIT	3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Surgery: Light, thermal, and electrical application 67/129
VIEW PATENT	@ USPTO: Full Text PDF

08744779 — Methods and apparatus for drug modeling and displaying drug models

US 08744779	Syroid et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Noah Syroid (Salt Lake City, Utah); Dwayne R. Westenskow (Salt Lake City, Utah); James Agutter (Salt Lake City, Utah); Talmage D. Egan (Salt Lake City, Utah); Kenward B. Johnson (Sandy, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Noah Syroid (Salt Lake City, Utah); Dwayne R. Westenskow (Salt Lake City, Utah); James Agutter (Salt Lake City, Utah); Talmage D. Egan (Salt Lake City, Utah); Kenward B. Johnson (Sandy, Utah)
ABSTRACT	Drug delivery models, displays, and systems may be configured to provide a clinician with readily intuitive information about the effects of one or more drugs on a subject. Interactive features may be included to provide a subject-specific model of the expected or predicted effects of one or more drugs on the subject. Additionally, interactive features that effect drug delivery to the subject may also be included. Drug delivery models, displays, and systems may be used in teaching, in advance of treatment, during treatment, or following treatment.
FILED	Friday, January 27, 2012
APPL NO	13/360642
ART UNIT	1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Electric Digital Data Processing G06F 19/3437 (20130101) Original (OR) Class G06F 19/3456 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of Defense (DOD)

08739390 — Method for microcontact printing of MEMS

US 08739390	Bulovic et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Vladimir Bulovic (Lexington, Massachusetts); Corinne Evelyn Packard (Somerville, Massachusetts); Jennifer Jong-Hua Yu (Palo Alto, California); Apoorva Murarka (Cambridge, Massachusetts); LeeAnn Kim (Somerville, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Carridge, Massachusetts)
INVENTOR(S)	Vladimir Bulovic (Lexington, Massachusetts); Corinne Evelyn Packard (Somerville, Massachusetts); Jennifer Jong-Hua Yu (Palo Alto, California); Apoorva Murarka (Cambridge, Massachusetts); LeeAnn Kim (Somerville, Massachusetts)
ABSTRACT	The embodiments disclosed herein are directed to fabrication methods useful for creating MEMS via microcontact printing by using small organic molecule release layers. The disclose method enables transfer of a continuous metal film onto a discontinuous platform to form a variable capacitor array. The variable capacitor array can produce mechanical motion under the application of a voltage. The methods disclosed herein eliminate masking and other traditional MEMS fabrication methodology. The methods disclosed herein can be used to form a substantially transparent MEMS having a PDMS layer interposed between an electrode and a graphene diaphragm.
FILED	Sunday, December 13, 2009
APPL NO	12/636757
ART UNIT	3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Metal working 029/622
VIEW PATENT	@ USPTO: Full Text PDF

08739508 — Shock cancellation mechanism for the control of unsteady interaction in contra-rotating high- and low-pressure turbines

US 08739508	Clark
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	John P. Clark (Dayton, Ohio)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	John P. Clark (Dayton, Ohio)
ABSTRACT	In a high pressure turbine used in combination with a contra-rotating low pressure turbine, in which the geometry of the inlet guide vane of the low pressure turbine induces a reflection of the incident shock wave from the high pressure turbine airfoil that propagates back upstream to impact the blade thereby denigrating both the performance of the high pressure turbine and its durability. The shock wave reflection is eliminated by fitting the downstream vanes with holes or indentations that allow jets of compressor bleed air to penetrate the boundary layer and induce a net velocity component across the main-flow direction in the near-wall region. This induced flow component acts to cancel the net flow component created by the moving shock from the upstream blade row thereby obviating the reflection that occurs naturally to cancel the flow.
FILED	Tuesday, September 29, 2009
APPL NO	12/569015
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/39.162
VIEW PATENT	@ USPTO: Full Text PDF

08739550 — Two stage combustor with reformer

US 08739550	Etemad et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Shahrokh Etemad (Trumbull, Connecticut); Benjamin D. Baird (Rocky Hill, Connecticut); Subir Roychoudhury (Madison, Connecticut); William C. Pfefferle (Madison, Connecticut)
ASSIGNEE(S)	Precision Combustion, Inc. (North Haven, Connecticut)
INVENTOR(S)	Shahrokh Etemad (Trumbull, Connecticut); Benjamin D. Baird (Rocky Hill, Connecticut); Subir Roychoudhury (Madison, Connecticut); William C. Pfefferle (Madison, Connecticut)
ABSTRACT	The present invention provides a combustor for an aerospace gas turbine engine comprising two stages wherein each stage defines an inlet and an exit. The second stage inlet is in fluid communication with the first stage exit such that a first flowpath is defined and it passes substantially through the second stage. A plurality of flow channel tubes is positioned within the second stage and each flow channel tube passes sealingly through a header plate positioned upstream of the second stage inlet thereby defining a second flowpath that also passes substantially through the second stage. The first flowpath exit and the second flowpath exit are positioned adjacent and proximate to one another to provide for the generation of microflames or microflame jets exiting the second stage from between and around the flow channel tube exits. The first stage of the combustor provides a gasifier and a reformer. The present invention also may comprise an igniter for further combustion of the reacted products or an external heat source for start-up. The second stage also may comprise a microflame combustor.
FILED	Thursday, September 30, 2010
APPL NO	12/924671
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Power plants 060/780
VIEW PATENT	@ USPTO: Full Text PDF

08739675 — Armor panel system to deflect incoming projectiles

US 08739675	Tunis et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	George C. Tunis (Berlin, Maryland); Scott Kendall (Berlin, Maryland); Stephen L. Kinnebrew (Crisfield, Maryland)
ASSIGNEE(S)	Hardwire, LLC (Pocomoke, Maryland)
INVENTOR(S)	George C. Tunis (Berlin, Maryland); Scott Kendall (Berlin, Maryland); Stephen L. Kinnebrew (Crisfield, Maryland)
ABSTRACT	An armor panel system has a projectile-deflecting section having an outwardly facing surface. The projectile-deflecting section is formed of a material arranged in parallel layers, the layers arranged at a non-parallel angle to the outer surface. The non-parallel angles deflect or rotate an incoming projectile.
FILED	Monday, October 20, 2008
APPL NO	12/288443
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0471 (20130101) Original (OR) Class F41H 5/0478 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08739677 — Boresight verification device

US 08739677	Robbins et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	James Travis Robbins (Dahlgren, Virginia); Luis J. Rodriguez (King George, Virginia); Danny L. Wilson (Spotsylvania, Virginia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	James Travis Robbins (Dahlgren, Virginia); Luis J. Rodriguez (King George, Virginia); Danny L. Wilson (Spotsylvania, Virginia)
ABSTRACT	A boresight verification device (BVD) comprised of a circular housing with a rear portion of smaller diameter and a front portion of larger diameter. The front portion securely holds a level. The circular housing also contains a plurality of spring plungers which grip the inside of a muzzle when BVD is inserted into a muzzle for use. A tooling ball provides a stable reference point.
FILED	Monday, December 05, 2011
APPL NO	13/374177
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Ordnance 089/41.190
VIEW PATENT	@ USPTO: Full Text PDF

08740102 — Gas turbine engine valve

US 08740102	Edwards
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	Daniel G. Edwards (Brownsburg, Indiana)
ASSIGNEE(S)	Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S)	Daniel G. Edwards (Brownsburg, Indiana)
ABSTRACT	A gas turbine engine valve is disclosed. In one form the valve includes two inlets in fluid communication with an outlet. The valve can include a spool having two lands capable of selectively closing either of the two inlets. The valve can include energy storage devices that initially position the spool within a valve housing. A temperature motor is provided to position the spool based upon a temperature of a mixture of working fluid from the two inlets. A working fluid flowing into the first inlet can be in fluid communication with a second end of the valve; and a working fluid flowing into the second inlet can be in fluid communication with a first end of the valve. A relatively high pressure condition at one or the other of the inlets can be used to alter a position of the valve.
FILED	Tuesday, November 24, 2009
APPL NO	12/625429
ART UNIT	3744 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Automatic temperature and humidity regulation 236/93.A00
VIEW PATENT	@ USPTO: Full Text PDF

08741196 — Method and apparatus for locating and drilling a hole in a composite

US 08741196	McCracken
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	John E. McCracken (Glen Mills, Pennsylvania)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	John E. McCracken (Glen Mills, Pennsylvania)
ABSTRACT	A body may be provided having first and second ends having threaded outer surfaces. A bore may extend between the first and second ends. A tool may be provided having a first outer mold-line surface, a second opposing surface, and a hole extending between the first and second opposing surfaces. The first end may be threadedly attached and sealed, at the second opposing surface, to an inner surface of the hole. A cap may be threadedly attached and sealed to the second end of the body. A composite may be consolidated against the first outer mold-line surface of the tool. The cap may be unthreadedly removed from the second end. A drill bit may be inserted into the bore, through the tool hole, and against the composite to drill a composite hole.
FILED	Thursday, October 01, 2009
APPL NO	12/571910
ART UNIT	1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Plastic and nonmetallic article shaping or treating: Processes 264/163
VIEW PATENT	@ USPTO: Full Text PDF

08741387 — Process and system for distributing particles for incorporation within a composite structure

US 08741387	Vontell et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Naval Air Systems Command (NAVAIR)
APPLICANT(S)	John H. Vontell (Manchester, Connecticut); John Putnam (Lindenhurst, Illinois)
ASSIGNEE(S)	United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S)	John H. Vontell (Manchester, Connecticut); John Putnam (Lindenhurst, Illinois)
ABSTRACT	A system and process is disclosed for binding particles to a carrier material in an isolated relationship for use in composite fabrication. A slurry comprising particles dispersed in fluid is created in particle suspension tanks, deposited as a uniform layer and filtered using reduced pressure applied to a filter belt to leave behind isolated particles, the reduced pressure further acting to overcome electrostatic and other forces of attraction between the particles until they can be permanently bound to the carrier with a binder or adhesive and collected on a take-up roll.
FILED	Friday, October 24, 2008
APPL NO	12/258214
ART UNIT	1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/294
VIEW PATENT	@ USPTO: Full Text PDF

08741432 — Fluoroalkylsilanated mesoporous metal oxide particles and methods of preparation thereof

US 08741432	Campos et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Raymond Campos (Lancaster, California); Timothy Haddad (Lancaster, California); Joseph M. Mabry (Lancaster, California); Andrew J. Guenthner (Lancaster, California)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Raymond Campos (Lancaster, California); Timothy Haddad (Lancaster, California); Joseph M. Mabry (Lancaster, California); Andrew J. Guenthner (Lancaster, California)
ABSTRACT	Coated particles comprise a core of fumed or precipitated inorganic metal oxide having a surface area of about 50 to about 500 square meters per gram and a shell consisting of an array of fluoroalkyl molecular chains at a density of at least 1 chain per square nanometer, joined to the core by covalent chemical bonds and with a total organic content of at least 9.9 percent by weight. These particles are formed by the chemical attachment of fluoroalkyl-alkylsilanes after exposure to an alkylamine and followed by an extraction to remove any organic material not covalently bound. The dense packing of molecular chains in the fluoroalkyl shell combined with a mesoporous structure imparts a very low surface energy, a very high specific surface area, and surface texture over a wide range of length scales. Such features are highly desirable for the creation of, for example, superhydrophobic and superoleophobic surfaces, separation media, and release films.
FILED	Wednesday, August 10, 2011
APPL NO	13/206994
ART UNIT	1788 — Miscellaneous Articles, Stock Material
CURRENT CPC	Stock material or miscellaneous articles 428/403
VIEW PATENT	@ USPTO: Full Text PDF

08741573 — Consensus coding sequences of human breast and colorectal cancers

US 08741573	Sjoblom et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Center for Research Resources (NCRR)
APPLICANT(S)	Tobias Sjoblom (Baltimore, Maryland); Sian Jones (Baltimore, Maryland); D. Williams Parsons (Baltimore, Maryland); Laura D. Wood (Baltimore, Maryland); Jimmy Lin (Baltimore, Maryland); Thomas Barber (Baltimore, Maryland); Diana Mandelker (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Victor E. Velculesu (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Tobias Sjoblom (Baltimore, Maryland); Sian Jones (Baltimore, Maryland); D. Williams Parsons (Baltimore, Maryland); Laura D. Wood (Baltimore, Maryland); Jimmy Lin (Baltimore, Maryland); Thomas Barber (Baltimore, Maryland); Diana Mandelker (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Victor E. Velculesu (Baltimore, Maryland)
ABSTRACT	Analysis of 13,023 genes in 11 breast and 11 colorectal cancers revealed that individual tumors accumulate an average of ˜90 mutant genes but that only a subset of these contribute to the neoplastic process. Using stringent criteria to delineate this subset, we identified 189 genes (average of 11 per tumor) that were mutated at significant frequency. The vast majority of these genes were not known to be genetically altered in tumors and are predicted to affect a wide range of cellular functions, including transcription, adhesion, and invasion. These data define the genetic landscape of two human cancer types, provide new targets for diagnostic and therapeutic intervention and monitoring.
FILED	Monday, August 13, 2007
APPL NO	12/377073
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/6.140
VIEW PATENT	@ USPTO: Full Text PDF

08741715 — Gate electrodes for millimeter-wave operation and methods of fabrication

US 08741715	Moore et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Marcia Moore (Santa Barbara, California); Sten Heikman (Goleta, California)
ASSIGNEE(S)	Cree, Inc. (Goleta, California)
INVENTOR(S)	Marcia Moore (Santa Barbara, California); Sten Heikman (Goleta, California)
ABSTRACT	A transistor device having a tiered gate electrode fabricated with methods using a triple layer resist structure. The triple layer resist stack is deposited on a semiconductor structure. An exposure pattern is written onto the resist stack using an e-beam writer, for example. The exposure dose is non-uniform across the device. Portions of the three resist layers are removed with a sequential development process, resulting in tiered resist structure. A conductive material is deposited to form the gate electrode. The resulting “Air-T” gate also has a three-tiered structure. The fabrication process is well-suited for the production of gates small enough for use in millimeter wave devices.
FILED	Wednesday, April 29, 2009
APPL NO	12/432478
ART UNIT	2893 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/270
VIEW PATENT	@ USPTO: Full Text PDF

08741832 — Pegylated albumin and uses thereof

US 08741832	Acharya et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Seetharama A. Acharya (Cresskill, New Jersey); Belur N. Manjula (Cresskill, New Jersey)
ASSIGNEE(S)	Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S)	Seetharama A. Acharya (Cresskill, New Jersey); Belur N. Manjula (Cresskill, New Jersey)
ABSTRACT	The present invention provides PEGylated hemoglobins and PEGylated albumins comprising polyethylene glycol (PEG) conjugated to hemoglobin or to albumin, wherein the PEG is a maleimide PEG, an alkylamide PEG, an iodoacetamide PEG, a p-nitro thio-phenyl PEG, a vinyl sulfone PEG, or a mixed disulfide PEG; and PEGylated albumins and PEGylated hemoglobins comprising polyethylene glycol (PEG) attached to a thiolated amino group of albumin or hemoglobin, wherein the amino group is thiolated using dithio sulfo succinimidyl propionate (DTSSP) or dithiosuccinimidyl propionate (DTSP) or dithiobispropionimidate. The invention also provides methods of preparing PEGylated hemoglobins and PEGylated albumins comprising a) reacting hemoglobin or albumin with a thiolating agent and with a PEGylating agent, and b) capping unPEGylated reactive thiols of hemoglobin or albumin with N-ethyl maleimide.
FILED	Friday, June 09, 2006
APPL NO	11/921064
ART UNIT	1676 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Original (OR) Class Peptides C07K 14/76 (20130101) C07K 14/805 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08741869 — Oligodeoxynucleotide and its use to induce an immune response

US 08741869	Klinman et al.
FUNDED BY	Department of Defense (DOD) Uniformed Services University of the Health Sciences (USUHS) Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Uniformed Services University of the Health Sciences, an institution of higher learning within the Department of Defense (Washington, District of Columbia)
INVENTOR(S)	Dennis M. Klinman (Potomac, Maryland); Ken J. Ishii (Osaka, Japan); Daniela Verthelyi (Potomac, Maryland); James J. Mond (Silver Spring, Maryland)
ABSTRACT	A substantially pure or isolated oligodeoxynucleotide of at least 10 nucleotides is disclosed, wherein the oligodeoxynucleotide comprised a sequence represented by either formula: 5′ N₁N₂N₃T-CpG-WN₄N₅N₆3′ wherein the CpG motif is unmethylated, W is A or T, and N₁, N₂, N₃, N₄, N₅, and N₆are nucleotides, or the formula: 5′ RY-CpG-RY 3′ wherein the central CpG motif is unmethylated, R is A or G, and Y is C or T, as well as an oligodeoxynucleotide delivery complex and a pharmacological composition comprising the present inventive oligodeoxynucleotide, and a method of inducing an immune response by administering the present inventive oligodeoxynucleotide to a host. In some embodiments, the oligodeoxynucleotide includes the nucleic acid sequences set forth as SEQ ID NO: 137.
FILED	Tuesday, February 05, 2013
APPL NO	13/759922
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 514/44.R00
VIEW PATENT	@ USPTO: Full Text PDF

08742069 — Concentrated aqueous silk fibroin solution and use thereof

US 08742069	Kaplan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Dental and Craniofacial Research (NIDCR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea)
ABSTRACT	The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
FILED	Thursday, March 14, 2013
APPL NO	13/827304
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300
VIEW PATENT	@ USPTO: Full Text PDF

08742084 — Bioreactive agents

US 08742084	Rothschild et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Kenneth J. Rothschild (Newton, Massachusetts); Sanjay M. Sonar (Thane, India); Jerzy Olejnik (Brookline, Massachusetts)
ASSIGNEE(S)	The Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S)	Kenneth J. Rothschild (Newton, Massachusetts); Sanjay M. Sonar (Thane, India); Jerzy Olejnik (Brookline, Massachusetts)
ABSTRACT	This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily fluids, and nascent proteins from translation reactions. The invention also relates to targets isolated with conjugates which may be useful as pharmaceutical agents or compositions that can be administered to humans and other mammals. The invention further relates to kits comprised of agents and conjugates that can be used for the detection of diseases, disorders and individual substances in a complex background of substances.
FILED	Friday, September 14, 2012
APPL NO	13/616499
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/23.100
VIEW PATENT	@ USPTO: Full Text PDF

08742087 — Mucin antigen vaccine

US 08742087	Tang et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	MicroVAX, LLC (Manassas, Virginia)
ASSIGNEE(S)	MicroVAX, LLC (Manassas, Virginia)
INVENTOR(S)	Yucheng Tang (San Diego, California); Albert Deisseroth (Potomac, Maryland)
ABSTRACT	Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the polypeptide comprising a secretory signal, a mucin antigen and CD40 ligand. Also provided are methods of generating an immune response against cells expressing a mucin by administering an effective amount of the vector. Further provided are methods of generating an immune response against cancer cells expressing a mucin in an individual by administering an effective amount of the vector. Still further provided are methods of overcoming anergy to a mucin self antigen by administering an effective amount of the vector.
FILED	Tuesday, July 23, 2013
APPL NO	13/948573
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Organic compounds 536/23.400
VIEW PATENT	@ USPTO: Full Text PDF

08742111 — Synthesis of intermediate anilino methyl esters used in the production of synthetic opioid analgesics

US 08742111	Walz et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Aberdeen Proving Ground (APG) Combat Capabilities Development Command (CCDC) Chemical Biological Center (CCDC CBC) Research, Development and Engineering Command (RDECOM) Edgewood Chemical Biological Center (ECBC)
APPLICANT(S)	U.S. Army Edgewood Chemical Biological Center (APG, Maryland)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Andrew J Walz (Baltimore, Maryland); Fu-Lian Hsu (Potomac, Maryland)
ABSTRACT	An improved process or method of synthesis of carfentanil and other potent opioid analgesics of the N-alkyl 4-substituted 4-piperidinylamide class which can be used as morphine substitutes.
FILED	Thursday, February 21, 2013
APPL NO	13/773094
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Organic compounds 546/20
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08742183 — Production of aviation fuel from biorenewable feedstocks

US 08742183	McCall et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Michael J. McCall (Geneva, Illinois); Terry L. Marker (Palos Heights, Illinois); Richard E. Marinangeli (Arlington Heights, Illinois); Joseph A. Kocal (Glenview, Illinois)
ASSIGNEE(S)	UOP LLC (Des Plaines, Illinois)
INVENTOR(S)	Michael J. McCall (Geneva, Illinois); Terry L. Marker (Palos Heights, Illinois); Richard E. Marinangeli (Arlington Heights, Illinois); Joseph A. Kocal (Glenview, Illinois)
ABSTRACT	A process has been developed for producing aviation fuel from renewable feedstocks such as plant oils and animal fats and oils. The process involves treating a renewable feedstock by hydrogenating and deoxygenating to provide n-paraffins having from about 8 to about 24 carbon atoms. At least some of the n-paraffins are isomerized to improve cold flow properties. At least a portion of the paraffins are selectively cracked to provide paraffins meeting specifications for different aviation fuels such as JP-8.
FILED	Friday, September 26, 2008
APPL NO	12/238945
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry of hydrocarbon compounds 585/240
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08742557 — Die mounting stress isolator

US 08742557	Eskridge
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Armament Research, Development and Engineering Center (ARDEC) U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)	Mark H. Eskridge (Renton, Washington)
ASSIGNEE(S)	Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S)	Mark H. Eskridge (Renton, Washington)
ABSTRACT	One method of the present invention includes preparing a die with traces and pads as desired for the intended use of the die. A MEMS device is mounted to the die. The die is then mounted to a substrate of the same material as the die. The substrate is then mounted to a package. The die and/or the substrate may be flip-chip mounted.
FILED	Tuesday, June 19, 2007
APPL NO	11/765322
ART UNIT	2899 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/678
VIEW PATENT	@ USPTO: Full Text PDF

08742628 — Solid state circuit breaker

US 08742628	Urciuoli
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Damian P. Urciuoli (Bowie, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Damian P. Urciuoli (Bowie, Maryland)
ABSTRACT	A solid state circuit breaker includes a first terminal; a second terminal; a first wide-band gap field effect transistor coupled to the first terminal; a second wide-band gap field effect transistor coupled to the second terminal, wherein the first wide-band gap field effect transistor and the second wide-band gap field effect transistor are common-source connected to one another; and a bi-directional snubber device coupled to the first wide-band gap field effect transistor and the second wide-band gap field effect transistor. Such a solid state circuit breaker may also include a gate drive circuit coupled to the first wide-band gap field effect transistor and the second wide-band gap field effect transistor, where the gate drive circuit may comprise a voltage regulation stage and a drive stage.
FILED	Wednesday, April 28, 2010
APPL NO	12/768898
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Electrical transmission or interconnection systems 37/112
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08742733 — Methods and apparatuses for elimination of torque pulsation in doubly fed induction generators using the field reconstruction method

US 08742733	Kiani et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Morgan M. Kiani (Arlington, Texas); Wei Wang (Dallas, Texas); Babak Fahimi (Arlington, Texas); Wei-Jen Lee (Colleyville, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Morgan M. Kiani (Arlington, Texas); Wei Wang (Dallas, Texas); Babak Fahimi (Arlington, Texas); Wei-Jen Lee (Colleyville, Texas)
ABSTRACT	Methods and apparatuses for substantially eliminating torque pulsation in a doubly fed induction machine are disclosed. An example method comprises: measuring a stator current of the doubly fed induction machine, measuring a rotor current of the doubly fed induction machine, calculating a total magnetic flux density in an airgap of the doubly fed induction machine, calculating a tangential force density, calculating an electromagnetic torque, repeating the calculation of the electromagnetic torque over one electrical cycle to estimate a torque pulsation, determining a new rotor current that substantially eliminates the torque pulsation by referencing a set of optimal rotor currents in a look-up table, and changing the rotor current in response to the determination. Other embodiments are described and claimed.
FILED	Friday, April 29, 2011
APPL NO	13/098273
ART UNIT	2833 — Electrical Circuits and Systems
CURRENT CPC	Electricity: Single generator systems 322/44
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08742794 — Analog logic automata

US 08742794	Gershenfeld et al.
FUNDED BY	Department of Defense (DOD) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Neil Gershenfeld (Somerville, Massachusetts); Kailiang Chen (Cambridge, Massachusetts); Jonathan Leu (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Neil Gershenfeld (Somerville, Massachusetts); Kailiang Chen (Cambridge, Massachusetts); Jonathan Leu (Cambridge, Massachusetts)
ABSTRACT	A distributed, reconfigurable statistical signal processing apparatus comprises an array of discrete-time analog signal processing circuitry for statistical signal processing based on a local message-passing algorithm and digital configuration circuitry for controlling the functional behavior of the array of analog circuitry. The input signal to the apparatus may be expressed as a probabilistic representation. The analog circuitry may comprise computational elements arranged in a network, with a receiving module that assigns probability values when an input signal arrives and communicates the probability values to one of the computational elements, the computational elements producing outputs based on the assigned probability values. The signal processing apparatus may be an analog logic automata cell or an array of cells, wherein each cell is able to communicate with all neighboring cells.
FILED	Monday, April 13, 2009
APPL NO	12/422491
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Miscellaneous active electrical nonlinear devices, circuits, and systems 327/34
VIEW PATENT	@ USPTO: Full Text PDF

08742797 — Double switched track-and-hold circuit

US 08742797	Hoskins
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Michael J. Hoskins (Monument, Colorado)
ASSIGNEE(S)	Hittite Microwave Corporation (Chelmsford, Massachusetts)
INVENTOR(S)	Michael J. Hoskins (Monument, Colorado)
ABSTRACT	A double switched track-and-hold circuit includes an input buffer having a first switched amplifier circuit for passing an input signal in a track mode and isolating the input signal from a buffer output in a hold mode, and a track-and-hold core circuit responsive to the input buffer and having a second switched amplifier circuit for tracking the input signal in a track mode and isolating the input signal from a track-and-hold output in a hold mode. The first and second switching amplifier circuits turn off approximately simultaneously during the hold mode to provide enhanced isolation.
FILED	Tuesday, August 17, 2010
APPL NO	12/806600
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Miscellaneous active electrical nonlinear devices, circuits, and systems 327/94
VIEW PATENT	@ USPTO: Full Text PDF

08743149 — Meteorology and oceanography geospatial analysis toolset

US 08743149	Dykes et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	James D. Dykes (Slidell, Louisiana); Philip J. Fanguy (Picayune, Mississippi); Thomas Gray (Gulfport, Mississippi)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	James D. Dykes (Slidell, Louisiana); Philip J. Fanguy (Picayune, Mississippi); Thomas Gray (Gulfport, Mississippi)
ABSTRACT	System and method for providing access to ArcMap netCDF utilities and adding support for observational data to ArcMap including, but not limited to, comparing observational data to model data in a graphical manner, and maintaining the security classifications for each layer in ArcMap so that the highest security classification of the data being viewed is known at all times.
FILED	Monday, November 04, 2013
APPL NO	14/071622
ART UNIT	2617 — Electrical Circuits and Systems
CURRENT CPC	Computer graphics processing and selective visual display systems 345/660
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08743373 — Metrology of optics with high aberrations

US 08743373	Gutin et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Department of the Navy (DON)
APPLICANT(S)	Mikhail Gutin (Albany, New York); Xu-Ming Wang (Albany, New York)
ASSIGNEE(S)	Applied Science Innovations, Inc. (Troy, New York)
INVENTOR(S)	Mikhail Gutin (Albany, New York); Xu-Ming Wang (Albany, New York)
ABSTRACT	An interferometry method and associated system and computerized media for testing samples under test including those with high aberrations, comprising: situating a sample under test between a tilt mirror and a reference mirror, the tilt mirror tiltable with at least one degree of freedom about at least one tilt mirror axis, and further translatable along an axial line defined by a direction of propagation of a test wavefront from a source thereof; propagating the test wavefront toward the tilt mirror; after the test wavefront has been reflected by the tilt mirror, further propagating the test wavefront toward a reference mirror; and deriving a substantially complete first-tilt-alignment wavefront metrology of the sample under test from a plurality of first-tilt-alignment interferograms taken with the tilt mirror held fixed at a first predetermined tilt mirror angle while discreetly varying a displacement between the sample under test and the reference mirror.
FILED	Sunday, September 04, 2011
APPL NO	13/225467
ART UNIT	2877 — Optics
CURRENT CPC	Optics: Measuring and testing 356/512
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08743654 — Reflectivity maps

US 08743654	Sammelmann
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Gary S. Sammelmann (Panama City, Florida)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Gary S. Sammelmann (Panama City, Florida)
ABSTRACT	Systems and methods for embedding three-dimensional targets in realistic sonar images are provided. An actual or synthetic sonar image is first created and a reflectivity map is produced therefrom. A direct path bottom reverberation is calculated to which texture is added by multiplying the signal from a given point on the bottom at coordinates (x,y) by the reflectivity map R(x,y) at that point and in which targets are embedded. Echoes from targets and other noise sources are superimposed on the direct path bottom reverberation to generate raw unbeamformed stave data. The stave data is beamformed to produce the desired complex image with the desired targets naturally embedded therein.
FILED	Monday, January 24, 2011
APPL NO	12/931636
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/9307 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

08743657 — Resolution analysis using vector components of a scattered acoustic intensity field

US 08743657	Barton, III et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Robert J. Barton, III (North Kingstown, Rhode Island); Kevin B. Smith (Fairfax, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert J. Barton, III (North Kingstown, Rhode Island); Kevin B. Smith (Fairfax, Virginia)
ABSTRACT	A target analysis method that includes the steps of: illuminating a target with acoustic waves; positioning a device at multiple acoustic vector sensing positions about the target in a scattered acoustic field of reflected waves to simultaneously measure acoustic pressure and particle velocity at each vector sensing position; converting using a Hilbert transform the measured acoustic pressures and particle velocities into a complex signal having active real and reactive imaginary vector component; computing respective active and reactive acoustic intensities at each vector components; and mapping field structure nulls being zero crossings of the active and reactive intensities to a bitmap representation of decomposed scattered target acoustic intensities of the target.
FILED	Friday, April 22, 2011
APPL NO	13/066734
ART UNIT	3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/89 (20130101) Original (OR) Class G01S 15/8902 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08743995 — Wireless communication throughput enhancement based on delayed channel gain information

US 08743995	Tse et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	David Ngar Ching Tse (Berkeley, California); Mohammad Ali Maddah-Ali (Piscataway, New Jersey)
ABSTRACT	Channel gain information is utilized for determining linear, or non-linear, combinations of transmitted symbols to increase symbol throughput. The base station recombines symbols directed to different receivers in response to the channel gain information. Channel gain information, which is subject to delay, has been previously utilized merely for predicting current channel gains prior at the time of transmission. The present invention, however, utilizes the channel gain information to increase coding efficiency even when the channel gain information is not utilized for predicting current channel gains. The method, apparatus and systems of the invention are applicable to any configuration of multiple wireless transmission to multiple receivers.
FILED	Monday, May 20, 2013
APPL NO	13/898328
ART UNIT	2634 — Digital Communications
CURRENT CPC	Pulse or digital communications 375/267
VIEW PATENT	@ USPTO: Full Text PDF

08744009 — Reducing transmitter-to-receiver non-linear distortion at a transmitter prior to estimating and cancelling known non-linear distortion at a receiver

US 08744009	Kleider et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	John Kleider (Decatur, Georgia); Anthony Smith (Salt Lake City, Utah)
ASSIGNEE(S)	General Dynamics C4 Systems, Inc. (Scottsdale, Arizona)
INVENTOR(S)	John Kleider (Decatur, Georgia); Anthony Smith (Salt Lake City, Utah)
ABSTRACT	A communication system is provided that includes a transmitter device and a receiver device. The transmitter device transmits input data as a transmitted signal having the known non-linear distortion (NLD) characteristic. The receiver receives a received signal that represents a channel affected version of the transmitted signal and that has the known NLD characteristic. The received signal includes power amplifier distortion (PAD) induced by the transmitter device's power amplifier. The receiver is designed to iteratively estimate, based on the known NLD characteristic, remaining PAD caused by the power amplifier, and to iteratively cancel estimated PAD to reduce PAD in the received signal.
FILED	Friday, September 25, 2009
APPL NO	12/567509
ART UNIT	2633 — Digital Communications
CURRENT CPC	Pulse or digital communications 375/316
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08744122 — System and method for object detection from a moving platform

US 08744122	Salgian et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Garbis Salgian (Princeton, New Jersey); John Benjamin Southall (Philadelphia, Pennsylvania); Sang-Hack Jung (Princeton, New Jersey); Vlad Branzoi (Princeton, New Jersey); Jiangjian Xiao (Plainsboro, New Jersey); Feng Han (Princeton, New Jersey); Supun Samarasekera (Montgomery, New Jersey); Rakesh Kumar (West Windsor, New Jersey); Jayan Eledath (Princeton, New Jersey)
ASSIGNEE(S)	SRI International (Menlo Park, California)
INVENTOR(S)	Garbis Salgian (Princeton, New Jersey); John Benjamin Southall (Philadelphia, Pennsylvania); Sang-Hack Jung (Princeton, New Jersey); Vlad Branzoi (Princeton, New Jersey); Jiangjian Xiao (Plainsboro, New Jersey); Feng Han (Princeton, New Jersey); Supun Samarasekera (Montgomery, New Jersey); Rakesh Kumar (West Windsor, New Jersey); Jayan Eledath (Princeton, New Jersey)
ABSTRACT	The present invention relates to a system and method for detecting one or more targets belonging to a first class (e.g., moving and/or stationary people), from a moving platform in a 3D-rich environment. The framework described here is implemented using a number of monocular or stereo cameras distributed around the vehicle to provide 360 degrees coverage. Furthermore, the framework described here utilizes numerous filters to reduce the number of false positive identifications of the targets.
FILED	Thursday, October 22, 2009
APPL NO	12/604298
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/103
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08744155 — Imaging or communications system utilizing multisample apodization and method

US 08744155	Walker et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	William F. Walker (Barboursville, Virginia); Drake A. Guenther (Annapolis, Maryland); Kevin Owen (Crozet, Virginia)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	William F. Walker (Barboursville, Virginia); Drake A. Guenther (Annapolis, Maryland); Kevin Owen (Crozet, Virginia)
ABSTRACT	Methods, systems and system components for optimizing contrast resolution of an imaging or sensing system utilizing multiple channels of broadband data associated with an array of transducers. Channels or data are filtered by passing the channels of data through finite impulse response (FIR) filters on each channel. The filters each have multiple taps having tap weights pre-calculated as a function of distance of the array from an object that energy is being transmitted to or reflected from. The weights are pre-computed through a deterministic equation based on an a priori system model.
FILED	Monday, February 16, 2009
APPL NO	12/371911
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/131
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08744185 — Efficient MCMC sampling with implicit shape representations

US 08744185	Chang et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	Jason Chang (Cambridge, Massachusetts); John William Fisher, III (Brookline, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Jason Chang (Cambridge, Massachusetts); John William Fisher, III (Brookline, Massachusetts)
ABSTRACT	In an approach for sampling a distribution of segmentations of an image, the segmentations are based on a level set function. For each sample of the distribution, the sampling includes the following, for each of multiple iterations: randomly selecting a set of locations of the level set function, determining a domain of allowed perturbations of the level set function at the selected set of locations, and randomly accepting a perturbation of the level set function according to a criterion corresponding to a biased distribution over the domain of allowed perturbations of the level set function, wherein the bias is selected to increase a probability of accepting the perturbation. The sampling also includes determining the sample of the distribution of segmentations according to a perturbed level set function determined in a final iteration of the multiple iterations for the sample.
FILED	Tuesday, April 17, 2012
APPL NO	13/448581
ART UNIT	2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/173
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08744215 — Methods and processes to aggregate multiple image feeds and dynamically select command reference frames

US 08744215	Handelman et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	David A. Handelman (Princeton, New Jersey); Haldun Komsuoglu (Philadelphia, Pennsylvania); Gordon H. Franken (New York, New York)
ASSIGNEE(S)	American Android Corp. (Highland, Maryland)
INVENTOR(S)	David A. Handelman (Princeton, New Jersey); Haldun Komsuoglu (Philadelphia, Pennsylvania); Gordon H. Franken (New York, New York)
ABSTRACT	Methods and systems to improve operator control of mobile robots are disclosed. The invention comprises in various embodiments the aggregation of multiple image feeds to improve operator situational awareness and the dynamic selection of command reference frames to improve operator intuitive control. The disclosed methods and systems reduce operator workload, reduce task completion times, and extend the capabilities of mobile manipulation systems.
FILED	Monday, June 27, 2011
APPL NO	13/169797
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/285
VIEW PATENT	@ USPTO: Full Text PDF

08744541 — Superconducting multi-bit digital mixer

US 08744541	Filippov et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Hypres, Inc. (Elmsford, New York)
ASSIGNEE(S)	Hypres, Inc. (Elmsford, New York)
INVENTOR(S)	Timur V. Filippov (Mahopac, New York); Alexander Kirichenko (Pleasantville, New York); Deepnarayan Gupta (Hawthorne, New York)
ABSTRACT	A superconducting multi-bit digital mixer, designed using rapid single flux quantum (RSFQ) logic, for multiplying two independent digital streams, at least one of these comprising a plurality of parallel bit lines, wherein the output is also a similar plurality of bit lines. In a preferred embodiment, one of the digital streams represents a local oscillator signal, and the other digital stream digital radio frequency input from an analog-to-digital converter. The multi-bit mixer comprises an array of bit-slices, with the local oscillator signal generated using shift registers. This multi-bit mixer is suitable for an integrated circuit with application to a broadband digital radio frequency receiver, a digital correlation receiver, or a digital radio frequency transmitter. A synchronous pulse distribution network is used to ensure proper operation at data rates of 20 GHz or above.
FILED	Tuesday, March 19, 2013
APPL NO	13/847023
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Superconductor technology: Apparatus, material, process 55/190
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08744783 — System and method for measuring power generated during legged locomotion

US 08744783	Templeman
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Robert E. Templeman (Bloomington, Indiana)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert E. Templeman (Bloomington, Indiana)
ABSTRACT	A system and method is provided for calculating power generated by a body during legged locomotion. The system includes at least one accelerometer to measure acceleration of the body during legged locomotion, at least one force sensor to measure a plurality of propulsive force impulses created by the body during legged locomotion, and a processor configured to calculate the power generated by the body during legged locomotion using output signals from both the at least one accelerometer and the at least one force sensor.
FILED	Thursday, August 27, 2009
APPL NO	12/548996
ART UNIT	2864 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/44
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08744992 — Method and system to predict a data value

US 08744992	Duchon
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Andrew P. Duchon (Newton, Massachusetts)
ASSIGNEE(S)	Aptima, Inc. (Woburn, Massachusetts)
INVENTOR(S)	Andrew P. Duchon (Newton, Massachusetts)
ABSTRACT	Embodiments of the present invention include methods and systems for predicting the likelihood of topics appearing in a set of data such as text. A number of latent variable methods are used to convert the data into a set of topics, topic values and topic profiles. A number of time-course methods are used to model how topic values change given previous topic profiles, or to find historical times with similar topic values and then projecting the topic profile forward from that historical time to predict the likelihood of the topics appearing. Embodiments include utilizing focus topics, such as valence topics, and data representing financial measures to predict the likelihood of topics. Methods and systems for modeling data and predicting the likelihood of topics over other dimensions are also contemplated.
FILED	Sunday, January 09, 2011
APPL NO	12/987147
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Data processing: Artificial intelligence 76/52
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08745185 — Method and apparatus for providing semantically aware network services

US 08745185	Salo
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Timothy J. Salo (Saint Paul, Minnesota)
ASSIGNEE(S)
INVENTOR(S)	Timothy J. Salo (Saint Paul, Minnesota)
ABSTRACT	A method and apparatus where network-layer devices use host-provided, detailed, per-packet, semantic information (DPPS information), which describes the content, meaning, importance, and/or other attributes of particular application data and is associated with each packet, to provide enhanced network services. In some embodiments of the above method, network-layer devices use DPPS information that includes QoS-related information to provide fine-grained, content-aware, and/or complex QoS assurances or similar services. In some embodiments, network-layer devices use DPPS information to provide network-based, application-protocol-independent, rate-adaptation services. In some embodiments, network-layer devices use DPPS information to provide highly efficient, application-protocol-independent, publish/subscribe dissemination services.
FILED	Friday, October 12, 2007
APPL NO	11/871157
ART UNIT	2458 — Computer Networks
CURRENT CPC	Electrical computers and digital processing systems: Multicomputer data transferring 79/223
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08745563 — Computationally efficient modeling and simulation of large scale systems

US 08745563	Jain et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) National Aeronautics and Space Administration (NASA) National Science Foundation (NSF)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Jitesh Jain (Rajasthan, India); Stephen F Cauley (West Lafayette, Indiana); Hong Li (He nan, China PRC); Cheng-Kok Koh (West Lafayette, Indiana); Vankataramanan Balakrishnan (West Lafayette, Indiana)
ABSTRACT	A system for simulating operation of a VLSI interconnect structure having capacitive and inductive coupling between nodes thereof, including a processor, and a memory, the processor configured to perform obtaining a matrix X and a matrix Y containing different combinations of passive circuit element values for the interconnect structure, the element values for each matrix including inductance L and inverse capacitance P, obtaining an adjacency matrix A associated with the interconnect structure, storing the matrices X, Y, and A in the memory, and performing numerical integration to solve first and second equations.
FILED	Monday, December 10, 2012
APPL NO	13/710145
ART UNIT	2851 — Printing/Measuring and Testing
CURRENT CPC	Computer-aided design and analysis of circuits and semiconductor masks 716/115
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08745718 — Delivery of authentication information to a RESTful service using token validation scheme

US 08745718	Dufel et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	Jericho Systems Corporation (Dallas, Texas)
ASSIGNEE(S)	Jericho Systems Corporation (Dallas, Texas)
INVENTOR(S)	Michael Dufel (Manitou Springs, Colorado); Vijayababu Subramanium (Columbia, South Carolina); Mizanul Chowdhury (Dorchester, Massachusetts)
ABSTRACT	Information useful for authenticating an entity is sent over a back channel during the authentication of an entity to a RESTful service. The delivery of the entity-related information is triggered by the validation of a service ticket received by the authentication component of the RESTful service.
FILED	Tuesday, October 02, 2012
APPL NO	13/633656
ART UNIT	2431 — Cryptography and Security
CURRENT CPC	Information security 726/9
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08745761 — Force feedback leveling of tip arrays for nanolithography

US 08745761	Mirkin et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Chad A. Mirkin (Wilmette, Illinois); Xing Liao (Evanston, Illinois); Adam B. Braunschweig (New York, New York)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Chad A. Mirkin (Wilmette, Illinois); Xing Liao (Evanston, Illinois); Adam B. Braunschweig (New York, New York)
ABSTRACT	A method of leveling a polymer pen array includes contacting a pen array with a surface and measuring a total force exerted on the surface by the pen array, the pen array being disposed at a first angle with respect to a first axis of the surface and a second angle with respect to a second axis of the surface; tilting one or both of the pen array and the surface to vary the first and second angles of the pen array with respect to the surface; measuring the total force exerted by the tilted pen array on the surface; and repeating the tilting and measuring steps until a global maximum of the total force exerted on the surface by the pen array is measured, thereby determining first and second angles which correspond to a leveled position of the pen array with respect to the surface.
FILED	Friday, December 03, 2010
APPL NO	12/960439
ART UNIT	2881 — Optics
CURRENT CPC	Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/55
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

08739603 — Apparatus for gas sorption measurement with integrated gas composition measurement device and gas mixing

US 08739603	Micklash, II et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	Wildcat Discovery Technologies, Inc. (San Diego, California)
ASSIGNEE(S)	Wildcat Discovery Technologies, Inc. (San Diego, California)
INVENTOR(S)	Kenneth James Micklash, II (Carmel, Indiana); Justin James Dutton (San Diego, California); Steven Kaye (San Diego, California)
ABSTRACT	An apparatus for testing of multiple material samples includes a gas delivery control system operatively connectable to the multiple material samples and configured to provide gas to the multiple material samples. Both a gas composition measurement device and pressure measurement devices are included in the apparatus. The apparatus includes multiple selectively openable and closable valves and a series of conduits configured to selectively connect the multiple material samples individually to the gas composition device and the pressure measurement devices by operation of the valves. A mixing system is selectively connectable to the series of conduits and is operable to cause forced mixing of the gas within the series of conduits to achieve a predetermined uniformity of gas composition within the series of conduits and passages.
FILED	Tuesday, December 18, 2012
APPL NO	13/718207
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/31.40
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08739773 — Oven rack having integral lubricious, dry porcelain surface

US 08739773	Ambrose et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	Jeffrey A. Ambrose (Evansville, Indiana); Gail Mackiewicz-Ludtka (Oak Ridge, Tennessee); Vinod K. Sikka (Oak Ridge, Tennessee); Jun Qu (Knoxville, Tennessee)
ASSIGNEE(S)	SSW Holding Company, Inc. (Fort Smith, Arkansas)
INVENTOR(S)	Jeffrey A. Ambrose (Evansville, Indiana); Gail Mackiewicz-Ludtka (Oak Ridge, Tennessee); Vinod K. Sikka (Oak Ridge, Tennessee); Jun Qu (Knoxville, Tennessee)
ABSTRACT	A lubricious glass-coated metal cooking article capable of withstanding repeated heating and cooling between room temperature and at least 500° F. without chipping or cracking the glass coating, wherein the glass coating includes about 0.1 to about 20% by weight of a homogeneously distributed dry refractory lubricant material having a particle size less than about 200 μm. The lubricant material is selected from the group consisting of carbon; graphite; boron nitride; cubic boron nitride; molybdenum (FV) sulfide; molybdenum sulfide; molybdenum (IV) selenide; molybdenum selenide, tungsten (IV) sulfide; tungsten disulfide; tungsten sulfide; silicon nitride (Si₃N₄); TiN; TiC; TiCN; TiO₂; TiAlN; CrN; SiC; diamond-like carbon; tungsten carbide (WC); zirconium oxide (ZrO₂); zirconium oxide and 0.1 to 40 weight % aluminum oxide; alumina-zirconia; antimony; antimony oxide; antimony trioxide; and mixtures thereof.
FILED	Thursday, May 24, 2007
APPL NO	12/301718
ART UNIT	3743 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Stoves and furnaces 126/337.R00
VIEW PATENT	@ USPTO: Full Text PDF

08740168 — Cryogenically cooled detector pin mount

US 08740168	Hunt, Jr. et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	William E. Hunt, Jr. (Fremont, California); Michael P. Chrisp (Danville, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC. (Livermore, California)
INVENTOR(S)	William E. Hunt, Jr. (Fremont, California); Michael P. Chrisp (Danville, California)
ABSTRACT	A focal plane assembly facilitates a molybdenum base plate being mounted to another plate made from aluminum. The molybdenum pin is an interference fit (press fit) in the aluminum base plate. An annular cut out area in the base plate forms two annular flexures.
FILED	Monday, March 14, 2011
APPL NO	13/046924
ART UNIT	3637 — Static Structures, Supports and Furniture
CURRENT CPC	Supports 248/346.10
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08740432 — Transmission of laser pulses with high output beam quality using step-index fibers having large cladding

US 08740432	Yalin et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Azer P. Yalin (Fort Collins, Colorado); Sachin Joshi (Fort Collins, Colorado)
ASSIGNEE(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S)	Azer P. Yalin (Fort Collins, Colorado); Sachin Joshi (Fort Collins, Colorado)
ABSTRACT	An apparatus and method for transmission of laser pulses with high output beam quality using large core step-index silica optical fibers having thick cladding, are described. The thick cladding suppresses diffusion of modal power to higher order modes at the core-cladding interface, thereby enabling higher beam quality, M², than are observed for large core, thin cladding optical fibers. For a given NA and core size, the thicker the cladding, the better the output beam quality. Mode coupling coefficients, D, has been found to scale approximately as the inverse square of the cladding dimension and the inverse square root of the wavelength. Output from a 2 m long silica optical fiber having a 100 μm core and a 660 μm cladding was found to be close to single mode, with an M²=1.6. Another thick cladding fiber (400 μm core and 720 μm clad) was used to transmit 1064 nm pulses of nanosecond duration with high beam quality to form gas sparks at the focused output (focused intensity of >100 GW/cm²), wherein the energy in the core was <6 mJ, and the duration of the laser pulses was about 6 ns. Extending the pulse duration provided the ability to increase the delivered pulse energy (>20 mJ delivered for 50 ns pulses) without damaging the silica fiber.
FILED	Thursday, August 25, 2011
APPL NO	13/218263
ART UNIT	2875 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/005 (20130101) Original (OR) Class G02B 6/028 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08740571 — Turbine bucket for use in gas turbine engines and methods for fabricating the same

US 08740571	Garcia-Crespo
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Andres Garcia-Crespo (Greenville, South Carolina)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Andres Garcia-Crespo (Greenville, South Carolina)
ABSTRACT	A turbine bucket for use with a turbine engine. The turbine bucket includes an airfoil that extends between a root end and a tip end. The airfoil includes an outer wall that defines a cavity that extends from the root end to the tip end. The outer wall includes a first ceramic matrix composite (CMC) substrate that extends a first distance from the root end to the tip end. An inner wall is positioned within the cavity. The inner wall includes a second CMC substrate that extends a second distance from the root end towards the tip end that is different than the first distance.
FILED	Monday, March 07, 2011
APPL NO	13/042034
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Fluid reaction surfaces 416/230
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08740573 — Adaptor assembly for coupling turbine blades to rotor disks

US 08740573	Delvaux et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	John McConnell Delvaux (Fountain Inn, South Carolina); Andres Jose Garcia-Crespo (Greenville, South Carolina); Kilmer Joseph Joyce (Jupiter, Florida); Allan Randall Tindell (Delray Beach, Florida)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	John McConnell Delvaux (Fountain Inn, South Carolina); Andres Jose Garcia-Crespo (Greenville, South Carolina); Kilmer Joseph Joyce (Jupiter, Florida); Allan Randall Tindell (Delray Beach, Florida)
ABSTRACT	An adaptor assembly for coupling a blade root of a turbine blade to a root slot of a rotor disk is disclosed. The adaptor assembly may generally include an adaptor body having a root configured to be received within the root slot. The adaptor body may also define a slot having an open end configured to receive the blade root. The adaptor body may further define a channel. The adaptor assembly may also include a plate having an outwardly extending foot. The foot may be configured to be received within the channel. Additionally, the plate may be configured to cover at least a portion of the open end of the slot when the foot is received within the channel.
FILED	Tuesday, April 26, 2011
APPL NO	13/094176
ART UNIT	3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Fluid reaction surfaces 416/248
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08740642 — Connector device for building integrated photovoltaic device

US 08740642	Keenihan et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	James R. Keenihan (Midland, Michigan); Joseph A. Langmaid (Caro, Michigan); Gerald K. Eurich (Merrill, Michigan); Michael J. Lesniak (Kawkawlin, Michigan); Michael H. Mazor (Midland, Michigan); Robert J. Cleereman (Midland, Michigan); Ryan S. Gaston (Midland, Michigan)
ASSIGNEE(S)	Dow Global Technologies LLC (Midland, Michigan)
INVENTOR(S)	James R. Keenihan (Midland, Michigan); Joseph A. Langmaid (Caro, Michigan); Gerald K. Eurich (Merrill, Michigan); Michael J. Lesniak (Kawkawlin, Michigan); Michael H. Mazor (Midland, Michigan); Robert J. Cleereman (Midland, Michigan); Ryan S. Gaston (Midland, Michigan)
ABSTRACT	The present invention is premised upon a connector device and method that can more easily electrically connect a plurality of PV devices or photovoltaic system components and/or locate these devices/components upon a building structure. It also may optionally provide some additional sub-components (e.g. at least one bypass diode and/or an indicator means) and may enhance the serviceability of the device.
FILED	Friday, May 01, 2009
APPL NO	12/989742
ART UNIT	2833 — Electrical Circuits and Systems
CURRENT CPC	Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/79 (20130101) Original (OR) Class
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08741060 — System and method for liquid silicon containment

US 08741060	Cliber et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	AMG IdealCast Solar Corporation (Wayne, Pennsylvania)
ASSIGNEE(S)	AMG IdealCast Solar Corporation (Wayne, Pennsylvania)
INVENTOR(S)	James A. Cliber (Emmitsburg, Maryland); Roger F. Clark (Knoxville, Maryland); Nathan G. Stoddard (Gettysburg, Pennsylvania); Paul Von Dollen (Frederick, Maryland)
ABSTRACT	This invention relates to a system and a method for liquid silicon containment, such as during the casting of high purity silicon used in solar cells or solar modules. The containment apparatus includes a shielding ember adapted to prevent breaching molten silicon from contacting structural elements or cooling elements of a casting device, and a volume adapted to hold a quantity of breaching molten silicon with the volume formed by a bottom and one or more sides.
FILED	Monday, April 01, 2013
APPL NO	13/854256
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/73
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08741079 — Electrical-assisted double side incremental forming and processes thereof

US 08741079	Roth et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	John Roth (Mckean, Pennsylvania); Jian Cao (Wilmette, Illinois)
ASSIGNEE(S)	The Penn State Research Foundation (University Park, Pennsylvania); Northwestern University (Evanston, Illinois)
INVENTOR(S)	John Roth (Mckean, Pennsylvania); Jian Cao (Wilmette, Illinois)
ABSTRACT	A process for forming a sheet metal component using an electric current passing through the component is provided. The process can include providing a double side incremental forming machine, the machine operable to perform a plurality of double side incremental deformations on the sheet metal component and also apply an electric direct current to the sheet metal component during at least part of the forming. The direct current can be applied before or after the forming has started and/or be terminated before or after the forming has stopped. The direct current can be applied to any portion of the sheet metal. The electrical assistance can reduce the magnitude of force required to produce a given amount of deformation, increase the amount of deformation exhibited before failure and/or reduce any springback typically exhibited by the sheet metal component.
FILED	Tuesday, August 30, 2011
APPL NO	13/221304
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Metal treatment 148/566
VIEW PATENT	@ USPTO: Full Text PDF

08741119 — Actinide ion sensor for pyroprocess monitoring

US 08741119	Jue et al.
FUNDED BY	Department of Energy (DOE) Office of Nuclear Energy (DOE-NE) Idaho National Laboratory (INL) Federally Funded Research and Development Center (FFRDC) Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S)	Jan-fong Jue (Idaho Falls, Idaho); Shelly X. Li (Idaho Falls, Idaho)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Jan-fong Jue (Idaho Falls, Idaho); Shelly X. Li (Idaho Falls, Idaho)
ABSTRACT	An apparatus for real-time, in-situ monitoring of actinide ion concentrations which comprises a working electrode, a reference electrode, a container, a working electrolyte, a separator, a reference electrolyte, and a voltmeter. The container holds the working electrolyte. The voltmeter is electrically connected to the working electrode and the reference electrode and measures the voltage between those electrodes. The working electrode contacts the working electrolyte. The working electrolyte comprises an actinide ion of interest. The reference electrode contacts the reference electrolyte. The reference electrolyte is separated from the working electrolyte by the separator. The separator contacts both the working electrolyte and the reference electrolyte. The separator is ionically conductive to the actinide ion of interest. The reference electrolyte comprises a known concentration of the actinide ion of interest. The separator comprises a beta double prime alumina exchanged with the actinide ion of interest.
FILED	Thursday, March 03, 2011
APPL NO	13/039451
ART UNIT	1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemistry: Electrical and wave energy 24/415
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08741174 — Reduced weight decontamination formulation for neutralization of chemical and biological warfare agents

US 08741174	Tucker
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Mark D. Tucker (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Mark D. Tucker (Albuquerque, New Mexico)
ABSTRACT	A reduced weight DF-200 decontamination formulation that is stable under high temperature storage conditions. The formulation can be pre-packed as an all-dry (i.e., no water) or nearly-dry (i.e., minimal water) three-part kit, with make-up water (the fourth part) being added later in the field at the point of use.
FILED	Wednesday, May 21, 2008
APPL NO	12/124191
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Compositions 252/186.410
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08741237 — Solvent extraction system for plutonium colloids and other oxide nano-particles

US 08741237	Soderholm et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Lynda Soderholm (Lemont, Illinois); Richard E. Wilson (Oak Park, Illinois); Renato Chiarizia (Elmhurst, Illinois); Suntharalingam Skanthakumar (Bolingbrook, Illinois)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Lynda Soderholm (Lemont, Illinois); Richard E. Wilson (Oak Park, Illinois); Renato Chiarizia (Elmhurst, Illinois); Suntharalingam Skanthakumar (Bolingbrook, Illinois)
ABSTRACT	The invention provides a method for extracting plutonium from spent nuclear fuel, the method comprising supplying plutonium in a first aqueous phase; contacting the plutonium aqueous phase with a mixture of a dielectric and a moiety having a first acidity so as to allow the plutonium to substantially extract into the mixture; and contacting the extracted plutonium with second a aqueous phase, wherein the second aqueous phase has a second acidity higher than the first acidity, so as to allow the extracted plutonium to extract into the second aqueous phase. The invented method facilitates isolation of plutonium polymer without the formation of crud or unwanted emulsions.
FILED	Monday, April 12, 2010
APPL NO	12/758106
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemistry of inorganic compounds 423/8
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08741258 — Production of hydrogen, liquid fuels, and chemicals from catalytic processing of bio-oils

US 08741258	Huber et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	George W. Huber (Belchertown, Massachusetts); Tushar P. Vispute (Tonawanda, New York); Kamalakanta Routray (Paducah, Kentucky)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	George W. Huber (Belchertown, Massachusetts); Tushar P. Vispute (Tonawanda, New York); Kamalakanta Routray (Paducah, Kentucky)
ABSTRACT	Disclosed herein is a method of generating hydrogen from a bio-oil, comprising hydrogenating a water-soluble fraction of the bio-oil with hydrogen in the presence of a hydrogenation catalyst, and reforming the water-soluble fraction by aqueous-phase reforming in the presence of a reforming catalyst, wherein hydrogen is generated by the reforming, and the amount of hydrogen generated is greater than that consumed by the hydrogenating. The method can further comprise hydrocracking or hydrotreating a lignin fraction of the bio-oil with hydrogen in the presence of a hydrocracking catalyst wherein the lignin fraction of bio-oil is obtained as a water-insoluble fraction from aqueous extraction of bio-oil. The hydrogen used in the hydrogenating and in the hydrocracking or hydrotreating can be generated by reforming the water-soluble fraction of bio-oil.
FILED	Friday, September 18, 2009
APPL NO	13/119750
ART UNIT	1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry of inorganic compounds 423/644
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08741386 — Atomic layer deposition of quaternary chalcogenides

US 08741386	Thimsen et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Elijah J. Thimsen (Chicago, Illinois); Shannon C. Riha (Park Ridge, Illinois); Alex B. F. Martinson (Woodridge, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Michael J. Pellin (Naperville, Illinois)
ASSIGNEE(S)	Uchicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Elijah J. Thimsen (Chicago, Illinois); Shannon C. Riha (Park Ridge, Illinois); Alex B. F. Martinson (Woodridge, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Michael J. Pellin (Naperville, Illinois)
ABSTRACT	Methods and systems are provided for synthesis and deposition of chalcogenides (including Cu₂ZnSnS₄). Binary compounds, such as metal sulfides, can be deposited by alternating exposures of the substrate to a metal cation precursor and a chalcogen anion precursor with purge steps between.
FILED	Friday, September 28, 2012
APPL NO	13/631135
ART UNIT	1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/255.700
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08741395 — Apparatus and method for carbon fiber surface treatment

US 08741395	Paulauskas et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	Felix L. Paulauskas (Knoxville, Tennessee); Daniel M. Sherman (Knoxville, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); Remaxco Technologies, LLC (Knoxville, Tennessee)
INVENTOR(S)	Felix L. Paulauskas (Knoxville, Tennessee); Daniel M. Sherman (Knoxville, Tennessee)
ABSTRACT	An apparatus and method for enhancing the surface energy and/or surface chemistry of carbon fibers involves exposing the fibers to direct or indirect contact with atmospheric pressure plasma generated using a background gas containing at least some oxygen or other reactive species. The fiber may be exposed directly to the plasma, provided that the plasma is nonfilamentary, or the fiber may be exposed indirectly through contact with gases exhausting from a plasma discharge maintained in a separate volume. In either case, the process is carried out at or near atmospheric pressure, thereby eliminating the need for vacuum equipment. The process may be further modified by moistening the fibers with selected oxygen-containing liquids before exposure to the plasma.
FILED	Monday, July 23, 2012
APPL NO	13/555476
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating processes 427/569
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08741491 — Ionic liquid containing sulfonate ions

US 08741491	Wolfe et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Derek Wolfe (Scottsdale, Arizona); Cody A. Friesen (Fort McDowell, Arizona); Paul Bryan Johnson (Phoenix, Arizona)
ASSIGNEE(S)	Fluidic, Inc. (Scottsdale, Arizona)
INVENTOR(S)	Derek Wolfe (Scottsdale, Arizona); Cody A. Friesen (Fort McDowell, Arizona); Paul Bryan Johnson (Phoenix, Arizona)
ABSTRACT	Embodiments are related to ionic liquids and more specifically to ionic liquids used in electrochemical metal-air cells in which the ionic liquid includes sulfonate ions as the anion.
FILED	Tuesday, April 17, 2012
APPL NO	13/448923
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Chemistry: Electrical current producing apparatus, product, and process 429/403
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08741654 — Compositions and methods for improved protein production

US 08741654	Bodie et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Elizabeth A. Bodie (San Carlos, California); Steve Sungjin Kim (Fremont, California)
ASSIGNEE(S)	Danisco US Inc. (Palo Alto, California)
INVENTOR(S)	Elizabeth A. Bodie (San Carlos, California); Steve Sungjin Kim (Fremont, California)
ABSTRACT	The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. 1, and are SEQ ID NOS.: 1-6, respectively. The present invention also provides host cells further comprising a nucleic acid encoding a desired heterologous protein such as an enzyme.
FILED	Tuesday, June 12, 2012
APPL NO	13/494889
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/484
VIEW PATENT	@ USPTO: Full Text PDF

08741657 — Nanocomposite thin films for optical gas sensing

US 08741657	Ohodnicki et al.
FUNDED BY	Department of Energy (DOE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)	U.S. Department of Energy (Washington, District of Columbia)
ASSIGNEE(S)	U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S)	Paul R. Ohodnicki (Alison Park, Pennsylvania); Thomas D. Brown (Finleyville, Pennsylvania)
ABSTRACT	The disclosure relates to a plasmon resonance-based method for gas sensing in a gas stream utilizing a gas sensing material. In an embodiment the gas stream has a temperature greater than about 500° C. The gas sensing material is comprised of gold nanoparticles having an average nanoparticle diameter of less than about 100 nanometers dispersed in an inert matrix having a bandgap greater than or equal to 5 eV, and an oxygen ion conductivity less than approximately 10⁻⁷S/cm at a temperature of 700° C. Exemplary inert matrix materials include SiO₂, Al₂O₃, and Si₃N₄as well as modifications to modify the effective refractive indices through combinations and/or doping of such materials. Changes in the chemical composition of the gas stream are detected by changes in the plasmon resonance peak. The method disclosed offers significant advantage over active and reducible matrix materials typically utilized, such as yttria-stabilized zirconia (YSZ) or TiO₂.
FILED	Monday, February 25, 2013
APPL NO	13/775447
ART UNIT	1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/102
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08741748 — Method to grow group III-nitrides on copper using passivation layers

US 08741748	Li et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Qiming Li (Albuquerque, New Mexico); George T. Wang (Albuquerque, New Mexico); Jeffrey T. Figiel (Albuquerque, New Mexico)
ABSTRACT	Group III-nitride epilayers can be grown directly on copper substrates using intermediate passivation layers. For example, single crystalline c-plane GaN can be grown on Cu (110) substrates with MOCVD. The growth relies on a low temperature AlN passivation layer to isolate any alloying reaction between Ga and Cu.
FILED	Friday, March 15, 2013
APPL NO	13/836594
ART UNIT	2894 — Semiconductors/Memory
CURRENT CPC	Semiconductor device manufacturing: Process 438/479
VIEW PATENT	@ USPTO: Full Text PDF

08741800 — Hydrothermal performance of catalyst supports

US 08741800	Elam et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Jeffrey W. Elam (Elmhurst, Illinois); Christopher L. Marshall (Naperville, Illinois); Joseph A. Libera (Clarendon Hills, Illinois); James A. Dumesic (Verona, Wisconsin); Yomaira J. Pagan-Torres (Madison, Wisconsin)
ASSIGNEE(S)	UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S)	Jeffrey W. Elam (Elmhurst, Illinois); Christopher L. Marshall (Naperville, Illinois); Joseph A. Libera (Clarendon Hills, Illinois); James A. Dumesic (Verona, Wisconsin); Yomaira J. Pagan-Torres (Madison, Wisconsin)
ABSTRACT	A high surface area catalyst with a mesoporous support structure and a thin conformal coating over the surface of the support structure. The high surface area catalyst support is adapted for carrying out a reaction in a reaction environment where the thin conformal coating protects the support structure within the reaction environment. In various embodiments, the support structure is a mesoporous silica catalytic support and the thin conformal coating comprises a layer of metal oxide resistant to the reaction environment which may be a hydrothermal environment.
FILED	Thursday, July 22, 2010
APPL NO	12/841805
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Catalyst, solid sorbent, or support therefor: Product or process of making 52/216
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08742107 — Process for manufacturing bis(2-methoxyethyl)-2,3,6,7-tetracyano-1,4,5,8,9,10-hexazaanthracene

US 08742107	Rasmussen et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Paul George Rasmussen (Ann Arbor, Michigan); Richard Graham Lawton (Ann Arbor, Michigan)
ASSIGNEE(S)	Vinazene, Inc. (Ann Arbor, Michigan)
INVENTOR(S)	Paul George Rasmussen (Ann Arbor, Michigan); Richard Graham Lawton (Ann Arbor, Michigan)
ABSTRACT	A process to manufacture substituted tetracyano-hexaazatricyclics with the substitutions occurring at the 9 and 10 hydrogens. The process begins with 2,3-dichloro-5,6-dicyanopyrazine, which is reacted to form the desired tetracyano-hexaazatricyclic. Different process embodiments enable different reaction paths to the desired tetracyano-hexaazatricyclic. Different tetracyano-hexaazatricyclic embodiments include bis(2-methoxyethyl)-2,3,6,7-tetracyano-1,4,5,8,9,10-hexazaanthracene and bis(2-methoxyethoxyethyl)-2,3,6,7-tetracyano-1,4,5,8,9,10-hexazaanthracene.
FILED	Sunday, December 02, 2012
APPL NO	13/691842
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Organic compounds 544/345
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08742152 — Preparation of metal-catecholate frameworks

US 08742152	Yaghi et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Omar M. Yaghi (Los Angeles, California); Felipe Gandara-Barragan (Los Angles, California); Zheng Lu (Knoxville, Tennessee); Shun Wan (Santa Monica, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Omar M. Yaghi (Los Angeles, California); Felipe Gandara-Barragan (Los Angles, California); Zheng Lu (Knoxville, Tennessee); Shun Wan (Santa Monica, California)
ABSTRACT	The disclosure provides for metal catecholate frameworks, and methods of use thereof, including gas separation, gas storage, catalysis, tunable conductors, supercapacitors, and sensors.
FILED	Wednesday, February 01, 2012
APPL NO	13/363792
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Organic compounds 556/113
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08742195 — Aluminum phosphate ceramics for waste storage

US 08742195	Wagh et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Arun Wagh (Naperville, Illinois); Martin D. Maloney (Evergreen, Colorado)
ASSIGNEE(S)	CH2M Hill, Inc. (Englewood, Colorado)
INVENTOR(S)	Arun Wagh (Naperville, Illinois); Martin D. Maloney (Evergreen, Colorado)
ABSTRACT	The present disclosure describes solid waste forms and methods of processing waste. In one particular implementation, the invention provides a method of processing waste that may be particularly suitable for processing hazardous waste. In this method, a waste component is combined with an aluminum oxide and an acidic phosphate component in a slurry. A molar ratio of aluminum to phosphorus in the slurry is greater than one. Water in the slurry may be evaporated while mixing the slurry at a temperature of about 140-200° C. The mixed slurry may be allowed to cure into a solid waste form. This solid waste form includes an anhydrous aluminum phosphate with at least a residual portion of the waste component bound therein.
FILED	Thursday, February 26, 2004
APPL NO	10/547100
ART UNIT	1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 25/36 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 12/02 (20130101) C04B 12/022 (20130101) C04B 14/303 (20130101) C04B 18/0463 (20130101) Original (OR) Class C04B 22/16 (20130101) C04B 28/342 (20130101) C04B 35/6309 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/304 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08742338 — Systems and methods for laser assisted sample transfer to solution for chemical analysis

US 08742338	Van Berkel et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S)	Gary J. Van Berkel (Clinton, Tennessee); Vilmos Kertesz (Knoxville, Tennessee); Olga S. Ovchinnikova (Knoxville, Tennessee)
ABSTRACT	Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing.
FILED	Wednesday, July 24, 2013
APPL NO	13/949777
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0463 (20130101) Original (OR) Class
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08742406 — Soft lithography microlens fabrication and array for enhanced light extraction from organic light emitting diodes (OLEDs)

US 08742406	Leung et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Ames Laboratory (AL) Federally Funded Research and Development Center (FFRDC) Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S)	Wai Y. Leung (Ames, Iowa); Joong-Mok Park (Ames, Iowa); Zhengqing Gan (Pleasant Hill, California); Kristen P. Constant (Ames, Iowa); Joseph Shinar (Ames, Iowa); Ruth Shinar (Ames, Iowa); Kai-Ming Ho (Ames, Iowa)
ASSIGNEE(S)	Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S)	Wai Y. Leung (Ames, Iowa); Joong-Mok Park (Ames, Iowa); Zhengqing Gan (Pleasant Hill, California); Kristen P. Constant (Ames, Iowa); Joseph Shinar (Ames, Iowa); Ruth Shinar (Ames, Iowa); Kai-Ming Ho (Ames, Iowa)
ABSTRACT	Provided are microlens arrays for use on the substrate of OLEDs to extract more light that is trapped in waveguided modes inside the devices and methods of manufacturing same. Light extraction with microlens arrays is not limited to the light emitting area, but is also efficient in extracting light from the whole microlens patterned area where waveguiding occurs. Large microlens array, compared to the size of the light emitting area, extract more light and result in over 100% enhancement. Such a microlens array is not limited to (O)LEDs of specific emission, configuration, pixel size, or pixel shape. It is suitable for all colors, including white, for microcavity OLEDs, and OLEDs fabricated directly on the (modified) microlens array.
FILED	Thursday, February 16, 2012
APPL NO	13/397749
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Active solid-state devices 257/40
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08742712 — Methods, systems and apparatus for controlling third harmonic voltage when operating a multi-phase machine in an overmodulation region

US 08742712	Perisic et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Milun Perisic (Torrance, California); Michael H Kinoshita (Redondo Beach, California); Ray M. Ransom (Big Bear City, California); Gabriel Gallegos-Lopez (Lomita, California)
ASSIGNEE(S)	GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S)	Milun Perisic (Torrance, California); Michael H Kinoshita (Redondo Beach, California); Ray M. Ransom (Big Bear City, California); Gabriel Gallegos-Lopez (Lomita, California)
ABSTRACT	Methods, system and apparatus are provided for controlling third harmonic voltages when operating a multi-phase machine in an overmodulation region. The multi-phase machine can be, for example, a five-phase machine in a vector controlled motor drive system that includes a five-phase PWM controlled inverter module that drives the five-phase machine. Techniques for overmodulating a reference voltage vector are provided. For example, when the reference voltage vector is determined to be within the overmodulation region, an angle of the reference voltage vector can be modified to generate a reference voltage overmodulation control angle, and a magnitude of the reference voltage vector can be modified, based on the reference voltage overmodulation control angle, to generate a modified magnitude of the reference voltage vector. By modifying the reference voltage vector, voltage command signals that control a five-phase inverter module can be optimized to increase output voltages generated by the five-phase inverter module.
FILED	Wednesday, January 26, 2011
APPL NO	13/014607
ART UNIT	2837 — Electrical Circuits and Systems
CURRENT CPC	Electricity: Motive power systems 318/599
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08743372 — Whispering-gallery-mode-based seismometer

US 08743372	Fourguette et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Dominique Claire Fourguette (Los Angeles, California); M. Volkan Otugen (Dallas, Texas); Liane Marie Larocque (Los Angeles, California); Greg Alan Ritter (Hamburg, Michigan); Jason Jeffrey Meeusen (Howell, Michigan); Tindaro Ioppolo (Dallas, Texas)
ASSIGNEE(S)	Michigan Aerospace Corporation (Ann Arbor, Michigan); Southern Methodist University (Dallas, Texas)
INVENTOR(S)	Dominique Claire Fourguette (Los Angeles, California); M. Volkan Otugen (Dallas, Texas); Liane Marie Larocque (Los Angeles, California); Greg Alan Ritter (Hamburg, Michigan); Jason Jeffrey Meeusen (Howell, Michigan); Tindaro Ioppolo (Dallas, Texas)
ABSTRACT	A whispering-gallery-mode-based seismometer provides for receiving laser light into an optical fiber, operatively coupling the laser light from the optical fiber into a whispering-gallery-mode-based optical resonator, operatively coupling a spring of a spring-mass assembly to a housing structure; and locating the whispering-gallery-mode-based optical resonator between the spring-mass assembly and the housing structure so as to provide for compressing the whispering-gallery-mode-based optical resonator between the spring-mass assembly and the housing structure responsive to a dynamic compression force from the spring-mass assembly responsive to a motion of the housing structure relative to an inertial frame of reference.
FILED	Tuesday, September 06, 2011
APPL NO	13/226466
ART UNIT	2886 — Optics
CURRENT CPC	Optics: Measuring and testing 356/480
VIEW PATENT	@ USPTO: Full Text PDF

08744036 — High power density liquid-cooled pebble-channel nuclear reactor

US 08744036	Peterson
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Per F. Peterson (Berkeley, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Per F. Peterson (Berkeley, California)
ABSTRACT	A high-temperature nuclear reactor, cooled by a liquid fluoride salt, is described. The reactor uses an annular fuel pebble comprised of an inert graphite center kernel, a TRISO fuel particles region, and a graphite outer shell, with an average pebble density lower than the density of the liquid salt so the pebbles float. The pebbles are introduced into a coolant entering the reactor and are carried into the bottom of the reactor core, where they form a pebble bed inside a plurality of vertical channels inside one or more replaceable Pebble Channel Assemblies (PCAs). Pebbles are removed through defueling chutes located at the top of each PCA. Each PCA also includes channels for insertion of neutron control and shutdown elements, and channels for insertion of core flux mapping and other instrumentation.
FILED	Monday, May 10, 2010
APPL NO	12/776599
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Nuclear Reactors G21C 3/30 (20130101) Original (OR) Class G21C 7/107 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08744791 — Automatic generation and analysis of solar cell IV curves

US 08744791	Kraft et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Steven M Kraft (Berkeley, California); Jason C. Jones (Berkeley, California)
ASSIGNEE(S)	SunPower Corporation (San Jose, California)
INVENTOR(S)	Steven M Kraft (Berkeley, California); Jason C. Jones (Berkeley, California)
ABSTRACT	A photovoltaic system includes multiple strings of solar panels and a device presenting a DC load to the strings of solar panels. Output currents of the strings of solar panels may be sensed and provided to a computer that generates current-voltage (IV) curves of the strings of solar panels. Output voltages of the string of solar panels may be sensed at the string or at the device presenting the DC load. The DC load may be varied. Output currents of the strings of solar panels responsive to the variation of the DC load are sensed to generate IV curves of the strings of solar panels. IV curves may be compared and analyzed to evaluate performance of and detect problems with a string of solar panels.
FILED	Tuesday, March 22, 2011
APPL NO	13/053770
ART UNIT	2862 — Printing/Measuring and Testing
CURRENT CPC	Data processing: Measuring, calibrating, or testing 72/65
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08745123 — Completion processing for data communications instructions

US 08745123	Blocksome et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Michael A. Blocksome (Rochester, Minnesota); Sameer Kumar (White Plains, New York); Jeffrey J. Parker (Rochester, Minnesota)
ABSTRACT	Completion processing of data communications instructions in a distributed computing environment, including receiving, in an active messaging interface (‘AMI’) data communications instructions, at least one instruction specifying a callback function; injecting into an injection FIFO buffer of a data communication adapter, an injection descriptor, each slot in the injection FIFO buffer having a corresponding slot in a pending callback list; listing in the pending callback list any callback function specified by an instruction, incrementing a pending callback counter for each listed callback function; transferring payload data as per each injection descriptor, incrementing a transfer counter upon completion of each transfer; determining from counter values whether the pending callback list presently includes callback functions whose data transfers have been completed; calling by the AMI any such callback functions from the pending callback list, decrementing the pending callback counter for each callback function called.
FILED	Friday, November 30, 2012
APPL NO	13/690168
ART UNIT	2457 — Computer Networks
CURRENT CPC	Electrical computers and digital processing systems: Multicomputer data transferring 79/201
VIEW PATENT	@ USPTO: Full Text PDF

National Science Foundation (NSF)

08739623 — Moisture sensors on conductive substrates

US 08739623	Chen et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	Zhi David Chen (Lexington, Kentucky); Ibrahim Yucedag (Duzce, Turkey)
ASSIGNEE(S)	The University of Kentucky Research Foundation (Lexinton, Kentucky)
INVENTOR(S)	Zhi David Chen (Lexington, Kentucky); Ibrahim Yucedag (Duzce, Turkey)
ABSTRACT	A moisture sensor includes a first electrode (a conductive substrate) having a first sensor portion and a first terminal portion as well as a second electrode having a second sensor portion and a second terminal portion. The moisture sensor also includes a layer of porous dielectric material sandwiched between the first sensor portion and the second sensor portion. Further the moisture sensor includes a layer of dense insulating material sandwiched between the first terminal portion and the second terminal portion. Leads are then connected to the two terminal portions.
FILED	Friday, March 09, 2012
APPL NO	13/416437
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/335.40
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08740618 — Braille module with compressible pin arrays

US 08740618	Shaw
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Keith N. Shaw (Gloucester, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Keith N. Shaw (Gloucester, Massachusetts)
ABSTRACT	A refreshable tactile reader apparatus for Braille text and graphics, utilizing a plurality of compressible tactile pins that can absorb strong downward forces. Such strong forces transmitted through tactile pins can damage pin actuation mechanisms. The physical enclosure of the reader provides open channels that allow the apparatus to be more easily cleaned than prior art enablements.
FILED	Friday, July 20, 2007
APPL NO	11/880360
ART UNIT	3715 — Amusement and Education Devices
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 21/003 (20130101) G09B 21/004 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

08741616 — Regio- and enantioselective alkane hydroxylation with modified cytochrome P450

US 08741616	Arnold et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	The California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Frances H. Arnold (La Canada, California); Matthew W. Peters (Pasadena, California); Peter Meinhold (Pasadena, California)
ABSTRACT	Cytochrome P450 BM-3 from Bacillus megaterium was engineered using a combination of directed evolution and site-directed mutagenesis to hydroxylate linear alkanes regio- and enantioselectively using atmospheric dioxygen as an oxidant. Mutant 9-10A-A328V hydroxylates octane primarily at the 2-positio to form S-2-octanol (40% ee). Another mutant, 1-12G, hydroxylates alkanes larger than hexane primarily at the 2-position, but forms R-2-alcohols (40-55% ee). These biocatalysts are highly active for alkane substrates and support thousands of product turnovers. These regio- and enantio-selectivities are retained in whole-cell biotransformations with E. coli, where the engineered P450s can be expressed at high levels and the expensive cofactor is supplied endogenously.
FILED	Friday, November 09, 2012
APPL NO	13/673977
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/189
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08741632 — One-step method for pretreating biomass using nanomixing

US 08741632	Lee et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Ilsoon Lee (Okemos, Michigan); Wei Wang (Lansing, Michigan); Shaowen Ji (East Lansing, Michigan)
ASSIGNEE(S)	Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Ilsoon Lee (Okemos, Michigan); Wei Wang (Lansing, Michigan); Shaowen Ji (East Lansing, Michigan)
ABSTRACT	Methods and devices for treatment of biomass comprised of crystalline structures are described that provide a combined mechanical, chemical and thermal effect (i.e., nano-hybrid pretreatment) to synergistically break down the crystalline structures. Such nano-hybrid mixing provides efficient, and cost-effective breakdown which enhances enzymatic accessibility to lignocellulosic materials. Methods and devices shown can be used to produce products such as pulp, chemicals, or biofuels.
FILED	Friday, July 29, 2011
APPL NO	13/194689
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Molecular biology and microbiology 435/289.100
VIEW PATENT	@ USPTO: Full Text PDF

08741801 — Catalytic platinum and its 3d-transition-metal alloy nanoparticles

US 08741801	Fang et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Jiye Fang (Vestal, New York); Jun Zhang (Binghamton, New York)
ASSIGNEE(S)	The Research Foundation for The State University of New York (Binghamton, New York)
INVENTOR(S)	Jiye Fang (Vestal, New York); Jun Zhang (Binghamton, New York)
ABSTRACT	Platinum (Pt)-based alloys are effective catalysts for oxygen reduction reaction (ORR) or fuel oxidation in proton exchange membrane fuel cells (PEMFCs). A wet-chemical approach for preparing monodisperse Pt₃Ni, Pt₃Co and Pt₃Fe nanocubes and Pt₃Ni nanoctahedra which are terminated with {100} and {111} facets, respectively, were developed. Such nanoscaled electrocatalysts supported on carbon black with controlled shape, e.g., octahedral configuration, is provided. ORR activity on the Pt₃Ni nanoctahedra is ˜5.1 fold higher than that of nanocubes with a similar size, and their C-supported samples are highly active with respect to commercial Pt/C.
FILED	Tuesday, November 23, 2010
APPL NO	12/953419
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Catalyst, solid sorbent, or support therefor: Product or process of making 52/326
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08742069 — Concentrated aqueous silk fibroin solution and use thereof

US 08742069	Kaplan et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute of Dental and Craniofacial Research (NIDCR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	David L. Kaplan (Concord, Massachusetts); Ung-Jin Kim (Daejeon, South Korea); Jaehyung Park (Decatur, Georgia); Hyoung-Joon Jin (Seoul, South Korea)
ABSTRACT	The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.
FILED	Thursday, March 14, 2013
APPL NO	13/827304
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300
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08742794 — Analog logic automata

US 08742794	Gershenfeld et al.
FUNDED BY	Department of Defense (DOD) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Neil Gershenfeld (Somerville, Massachusetts); Kailiang Chen (Cambridge, Massachusetts); Jonathan Leu (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Neil Gershenfeld (Somerville, Massachusetts); Kailiang Chen (Cambridge, Massachusetts); Jonathan Leu (Cambridge, Massachusetts)
ABSTRACT	A distributed, reconfigurable statistical signal processing apparatus comprises an array of discrete-time analog signal processing circuitry for statistical signal processing based on a local message-passing algorithm and digital configuration circuitry for controlling the functional behavior of the array of analog circuitry. The input signal to the apparatus may be expressed as a probabilistic representation. The analog circuitry may comprise computational elements arranged in a network, with a receiving module that assigns probability values when an input signal arrives and communicates the probability values to one of the computational elements, the computational elements producing outputs based on the assigned probability values. The signal processing apparatus may be an analog logic automata cell or an array of cells, wherein each cell is able to communicate with all neighboring cells.
FILED	Monday, April 13, 2009
APPL NO	12/422491
ART UNIT	2816 — Semiconductors/Memory
CURRENT CPC	Miscellaneous active electrical nonlinear devices, circuits, and systems 327/34
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08742851 — CMOS linear differential distributed amplifier and distributed active balun

US 08742851	Jahanian et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Electrical and Communications Systems (ECS)
APPLICANT(S)	Amin Jahanian (Irvine, California); Payam Heydari (Irvine, California)
ASSIGNEE(S)	The Regents of The University of California (Oakland, California)
INVENTOR(S)	Amin Jahanian (Irvine, California); Payam Heydari (Irvine, California)
ABSTRACT	A CMOS distributed amplifier with distributed active input balun is disclosed. Each g_mcell within the distributed amplifier employs dual-output two-stage topology that improves gain and linearity without adversely affecting bandwidth and power.
FILED	Thursday, May 31, 2012
APPL NO	13/485710
ART UNIT	2843 — Electrical Circuits and Systems
CURRENT CPC	Amplifiers 330/301
VIEW PATENT	@ USPTO: Full Text PDF

08743449 — Method and apparatus for providing high-fill-factor micromirror/micromirror arrays with surface mounting capability

US 08743449	Xie et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)	Huikai Xie (Gainesville, Florida); Kemiao Jia (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S)	Huikai Xie (Gainesville, Florida); Kemiao Jia (Gainesville, Florida)
ABSTRACT	Embodiments of the subject invention relate to micromirror devices and methods of fabricating a micromirror/micromirror array. According to an embodiment, micromirrors can be fabricated from a semiconductor substrate where after forming actuators and bonding pads on a front side of the semiconductor substrate, the device is flipped over to have a portion of the back side of the substrate removed and formed to become the mirror plate surface. The subject micromirrors can allow further miniaturization of endoscopes and other optical applications without sacrificing the optical aperture through their surface mounting capabilities.
FILED	Tuesday, June 01, 2010
APPL NO	13/148019
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 26/0841 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

08744214 — Navigating images using image based geometric alignment and object based controls

US 08744214	Snavely et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Microsoft Corporation (Redmond, Washington); University of Washington (Seattle, Washington)
ASSIGNEE(S)	Microsoft Corporation (Redmond, Washington); University of Washington (Seattle, Washington)
INVENTOR(S)	Keith Noah Snavely (Ithaca, New York); Steven Maxwell Seitz (Seattle, Washington); Richard Szeliski (Bellevue, Washington)
ABSTRACT	Over the past few years there has been a dramatic proliferation of digital cameras, and it has become increasingly easy to share large numbers of photographs with many other people. These trends have contributed to the availability of large databases of photographs. Effectively organizing, browsing, and visualizing such .seas. of images, as well as finding a particular image, can be difficult tasks. In this paper, we demonstrate that knowledge of where images were taken and where they were pointed makes it possible to visualize large sets of photographs in powerful, intuitive new ways. We present and evaluate a set of novel tools that use location and orientation information, derived semi-automatically using structure from motion, to enhance the experience of exploring such large collections of images.
FILED	Tuesday, May 21, 2013
APPL NO	13/898697
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image analysis 382/284
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08744770 — Path oracles for spatial networks

US 08744770	Samet et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Hanan Samet (College Park, Maryland); Jagan Sankaranarayanan (Santa Clara, California)
ASSIGNEE(S)	University of Maryland, College Park (College Park, Maryland)
INVENTOR(S)	Hanan Samet (College Park, Maryland); Jagan Sankaranarayanan (Santa Clara, California)
ABSTRACT	One embodiment of the invention is directed to a method including constructing a path-distance oracle that provides both an intermediate vertex of a shortest path between two vertices in a spatial network and an approximate distance between the two vertices. The constructing comprises decomposing the spatial network into a set of path-coherent pairs (PCPs) that satisfy at least one predefined property.
FILED	Friday, August 26, 2011
APPL NO	13/219163
ART UNIT	3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/00 (20130101) G01C 21/26 (20130101) G01C 21/3446 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/30241 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

08745563 — Computationally efficient modeling and simulation of large scale systems

US 08745563	Jain et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) National Aeronautics and Space Administration (NASA) National Science Foundation (NSF)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Jitesh Jain (Rajasthan, India); Stephen F Cauley (West Lafayette, Indiana); Hong Li (He nan, China PRC); Cheng-Kok Koh (West Lafayette, Indiana); Vankataramanan Balakrishnan (West Lafayette, Indiana)
ABSTRACT	A system for simulating operation of a VLSI interconnect structure having capacitive and inductive coupling between nodes thereof, including a processor, and a memory, the processor configured to perform obtaining a matrix X and a matrix Y containing different combinations of passive circuit element values for the interconnect structure, the element values for each matrix including inductance L and inverse capacitance P, obtaining an adjacency matrix A associated with the interconnect structure, storing the matrices X, Y, and A in the memory, and performing numerical integration to solve first and second equations.
FILED	Monday, December 10, 2012
APPL NO	13/710145
ART UNIT	2851 — Printing/Measuring and Testing
CURRENT CPC	Computer-aided design and analysis of circuits and semiconductor masks 716/115
VIEW PATENT	@ USPTO: Full Text PDF

08745761 — Force feedback leveling of tip arrays for nanolithography

US 08745761	Mirkin et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Engineering Education and Centers (EEC)
APPLICANT(S)	Chad A. Mirkin (Wilmette, Illinois); Xing Liao (Evanston, Illinois); Adam B. Braunschweig (New York, New York)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Chad A. Mirkin (Wilmette, Illinois); Xing Liao (Evanston, Illinois); Adam B. Braunschweig (New York, New York)
ABSTRACT	A method of leveling a polymer pen array includes contacting a pen array with a surface and measuring a total force exerted on the surface by the pen array, the pen array being disposed at a first angle with respect to a first axis of the surface and a second angle with respect to a second axis of the surface; tilting one or both of the pen array and the surface to vary the first and second angles of the pen array with respect to the surface; measuring the total force exerted by the tilted pen array on the surface; and repeating the tilting and measuring steps until a global maximum of the total force exerted on the surface by the pen array is measured, thereby determining first and second angles which correspond to a leveled position of the pen array with respect to the surface.
FILED	Friday, December 03, 2010
APPL NO	12/960439
ART UNIT	2881 — Optics
CURRENT CPC	Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/55
VIEW PATENT	@ USPTO: Full Text PDF

Department of Agriculture (USDA)

08741309 — Porcine reproductive and respiratory syndrome vaccine based on isolate JA-142

US 08741309	Mengeling et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	William L. Mengeling (Ames, Iowa); Ann Vorwald (Ames, Iowa); Kelly Lager (Neveda, Iowa); Mike Roof (Ames, Iowa); Kelly Burkhart (Radcliffe, Iowa); David E. Gorcyca (St. Joseph, Missouri)
ASSIGNEE(S)	The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia); Boehringer Ingelheim Vetmedica, Inc. (St. Joseph, Missouri)
INVENTOR(S)	William L. Mengeling (Ames, Iowa); Ann Vorwald (Ames, Iowa); Kelly Lager (Neveda, Iowa); Mike Roof (Ames, Iowa); Kelly Burkhart (Radcliffe, Iowa); David E. Gorcyca (St. Joseph, Missouri)
ABSTRACT	Substantially avirulent forms of atypical porcine reproductive and respiratory syndrome (PRRS) virus and corresponding vaccines are provided which result from cell culture passaging of virulent forms of PRRS. The resultant avirulent atypical PRRS virus is useful as a vaccine in that PRRS specific antibody response is elicited by inoculation of host animals, thereby conferring effective immunity against both previously known strains of PRRS virus and newly isolated atypical PRRS virus strains. The preferred passaging technique ensures that the virus remains in a logarithmic growth phase substantially throughout the process, which minimizes the time required to achieve attenuation. The present invention also provides diagnostic testing methods which can differentiate between animals infected with field strains and attenuated strains of PRRSV.
FILED	Monday, July 24, 2006
APPL NO	11/459542
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Drug, bio-affecting and body treating compositions 424/204.100
VIEW PATENT	@ USPTO: Full Text PDF

08742148 — Oligomerization of jojoba oil in super-critical CO₂for different applications

US 08742148	Liu et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Zengshe Liu (Morton, Illinois); Shailesh N. Shah (Sugar-Land, Texas)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Zengshe Liu (Morton, Illinois); Shailesh N. Shah (Sugar-Land, Texas)
ABSTRACT	Dimers of jojoba oil wax esters are prepared by reacting the wax esters in the presence of a catalytically effective amount of an acid catalyst in supercritical CO₂. In the reaction, the double bonds of the wax esters are opened and cross link or polymerize two wax esters as dimers. The jojoba ester dimers which are produced are of the formula: wherein R₁and R₁′ are independently selected from the group consisting of C15-C23 monounsaturated hydrocarbons, R₂and R₂′ are independently selected from the group consisting of C8-C14 saturated hydrocarbons, and R₃and R₃′ are independently selected from the group consisting of C6-C8 saturated hydrocarbons.
FILED	Tuesday, September 20, 2011
APPL NO	13/237072
ART UNIT	1672 — Organic Chemistry
CURRENT CPC	Organic compounds 554/26
VIEW PATENT	@ USPTO: Full Text PDF

08742305 — Methods and apparatuses for thermal treatment of foods and other biomaterials, and products obtained thereby

US 08742305	Simunovic et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Josip Simunovic (Raleigh, North Carolina); Kenneth R. Swartzel (Raleigh, North Carolina); Van-Den Truong (Raleigh, North Carolina); Gary Cartwright (Apex, North Carolina); Pablo Coronel (Cary, North Carolina); Kandiyan Puthalath Sandeep (Cary, North Carolina); David Parrott (Raleigh, North Carolina)
ASSIGNEE(S)	North Carolina State University (Raleigh, North Carolina); Industrial Microwave Systems, L.L.C. (Morrisville, North Carolina); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Josip Simunovic (Raleigh, North Carolina); Kenneth R. Swartzel (Raleigh, North Carolina); Van-Den Truong (Raleigh, North Carolina); Gary Cartwright (Apex, North Carolina); Pablo Coronel (Cary, North Carolina); Kandiyan Puthalath Sandeep (Cary, North Carolina); David Parrott (Raleigh, North Carolina)
ABSTRACT	Methods and apparatuses for thermally treating flowable materials using electromagnetic radiation, and foods and materials obtained thereby. Also provided are methods of continuous flow thermal treatment of biomaterials, apparatuses for performing the same, and products prepared using the methods and/or apparatuses.
FILED	Thursday, August 12, 2010
APPL NO	12/855338
ART UNIT	3742 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Electric heating 219/687
VIEW PATENT	@ USPTO: Full Text PDF

08742768 — Interrogation measurement system and method providing accurate permittivity measurements via ultra-wideband removal of spurious reflectors

US 08742768	Pelletier et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Mathew G. Pelletier (Idalou, Texas); Joseph A. Viera, Jr. (Manchester, New Hampshire); Gregory A. Holt (Brownfield, Texas); John D. Wanjura (Lubbock, Texas)
ASSIGNEE(S)	The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia); Microsemi Corporation (Alexandria, Virginia)
INVENTOR(S)	Mathew G. Pelletier (Idalou, Texas); Joseph A. Viera, Jr. (Manchester, New Hampshire); Gregory A. Holt (Brownfield, Texas); John D. Wanjura (Lubbock, Texas)
ABSTRACT	A method and apparatus for determining at least one property of a target material is disclosed. The method is constituted of: providing a time varying signal at comprising frequency content over a range of frequencies; transducing the provided signal so as to interact with the target material; receiving the provided time varying signal after interaction with the target material; mixing the received time varying signal with a portion of the provided time varying signal; determining the propagation delay associated with the target material of the received provided time varying signal at each of a plurality of frequencies within the range of frequencies; and determining at least one property of the target material responsive to the determined propagation delay at each of the plurality of frequencies.
FILED	Monday, August 22, 2011
APPL NO	13/214576
ART UNIT	2866 — Printing/Measuring and Testing
CURRENT CPC	Electricity: Measuring and testing 324/617
VIEW PATENT	@ USPTO: Full Text PDF

National Aeronautics and Space Administration (NASA)

08739620 — Liquid-sensing probe and methods for using the same

US 08739620	Haberbusch et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) John F. Kennedy Space Center (KSC)
APPLICANT(S)	Mark S. Haberbusch (Amherst, Ohio); Jacob C. Ickes (Fremont, Ohio); Adam Thurn (Clyde, Ohio); Branden J. Lawless (Mason, Ohio)
ASSIGNEE(S)	Sierra Lobo, Inc. (Fremont, Ohio)
INVENTOR(S)	Mark S. Haberbusch (Amherst, Ohio); Jacob C. Ickes (Fremont, Ohio); Adam Thurn (Clyde, Ohio); Branden J. Lawless (Mason, Ohio)
ABSTRACT	A sensor assembly includes a main body, a sensor, and a filler. The main body includes an outer surface having a continuously-variable radius of curvature in at least one portion. A sensor in thermal communication with a region of that surface having relatively low radius of curvature is disposed in the assembly recessed from the outer surface. Liquid droplets adhered to the outer surface in this region tend to migrate to a distant location having a higher radius of curvature. The main body has low thermal conductivity. The filler has a relatively higher thermal conductivity and, in embodiments, fills an opening in the outer surface of the main body, providing a thermally-conductive pathway between the sensor and the surrounding environment via the opening. A probe having a plurality of such sensors, and methods of detecting the presence of liquid and phase transitions in a predetermined space are also disclosed.
FILED	Friday, August 20, 2010
APPL NO	12/860394
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/295
VIEW PATENT	@ USPTO: Full Text PDF

08739638 — Star-shaped fluid flow tool for use in making differential measurements

US 08739638	England et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	John Dwight England (Arab, Alabama); Anthony R. Kelley (Sommerville, Alabama); Raymond J. Cronise (Huntsville, Alabama)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	John Dwight England (Arab, Alabama); Anthony R. Kelley (Sommerville, Alabama); Raymond J. Cronise (Huntsville, Alabama)
ABSTRACT	A fluid flow tool's plate-like structure has a ring portion defining a flow hole, a support portion extending radially away from the ring portion and adapted to be coupled to conduit wall, and extensions extending radially away from the ring portion such that a periphery of the plate-like structure is defined by the extensions and trough regions between adjacent extensions. One or more ports formed in the ring portion are in fluid communication with the flow hole. A first manifold in the plate-like structure is in fluid communication with each port communicating with the flow hole. One or more ports are formed in the periphery of the plate-like structure. A second manifold in the plate-like structure is in fluid communication with each port formed in the periphery. The first and second manifolds extend through the plate-like structure to terminate and be accessible at the conduit wall.
FILED	Tuesday, November 22, 2011
APPL NO	13/302817
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/861.650
VIEW PATENT	@ USPTO: Full Text PDF

08744224 — Tapered fiber bundle apparatus with monitoring capability

US 08744224	Wysocki
FUNDED BY	National Aeronautics and Space Administration (NASA) National Reconnaissance Office (NRO)
APPLICANT(S)	Paul F. Wysocki (Flemington, New Jersey)
ASSIGNEE(S)	Alcatel Lucent (Paris, France)
INVENTOR(S)	Paul F. Wysocki (Flemington, New Jersey)
ABSTRACT	Systems and methods for monitoring signals in an optical fiber amplifier system are provided. The optical amplifier system includes a tapered fiber bundle which couples optical energy into the cladding of an optical amplifier. A signal passing through the optical amplifier is amplified. To monitor the amplified signal, a single fiber of a tapered fiber bundle may be used as a monitor fiber. Alternatively, a monitor or coupler may be integrated into the tapered fiber bundle during manufacturing. The systems and methods disclosed allow for monitoring the amplified signal without increasing the length of the amplified signal's path, thus minimizing the introduction of additional non-linearities.
FILED	Tuesday, March 07, 2006
APPL NO	11/369364
ART UNIT	2874 — Optics
CURRENT CPC	Optical waveguides 385/43
VIEW PATENT	@ USPTO: Full Text PDF

08745563 — Computationally efficient modeling and simulation of large scale systems

US 08745563	Jain et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL) National Aeronautics and Space Administration (NASA) National Science Foundation (NSF)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Jitesh Jain (Rajasthan, India); Stephen F Cauley (West Lafayette, Indiana); Hong Li (He nan, China PRC); Cheng-Kok Koh (West Lafayette, Indiana); Vankataramanan Balakrishnan (West Lafayette, Indiana)
ABSTRACT	A system for simulating operation of a VLSI interconnect structure having capacitive and inductive coupling between nodes thereof, including a processor, and a memory, the processor configured to perform obtaining a matrix X and a matrix Y containing different combinations of passive circuit element values for the interconnect structure, the element values for each matrix including inductance L and inverse capacitance P, obtaining an adjacency matrix A associated with the interconnect structure, storing the matrices X, Y, and A in the memory, and performing numerical integration to solve first and second equations.
FILED	Monday, December 10, 2012
APPL NO	13/710145
ART UNIT	2851 — Printing/Measuring and Testing
CURRENT CPC	Computer-aided design and analysis of circuits and semiconductor masks 716/115
VIEW PATENT	@ USPTO: Full Text PDF

Department of Transportation (USDOT)

08739602 — Portable ultrafine particle sizer (PUPS) apparatus

US 08739602	Vize et al.
FUNDED BY	Department of Transportation (USDOT)
APPLICANT(S)	Andrew Vize (Wolcott, Vermont); Matthew Casari (Waterbury, Vermont); Britt Holmen (Burlington, Vermont); Jeff Frolik (Essex Junction, Vermont)
ASSIGNEE(S)	The University of Vermont and State Agricultural College (Burlington, Vermont)
INVENTOR(S)	Andrew Vize (Wolcott, Vermont); Matthew Casari (Waterbury, Vermont); Britt Holmen (Burlington, Vermont); Jeff Frolik (Essex Junction, Vermont)
ABSTRACT	The Portable Ultrafine Particle Sizer (PUPS) invention is provided. The PUPS is an instrument which can measure particle number concentration for particle sizes under 200 nanometers in-situ. The PUPS is a compact design for quick mounting on vehicles. Size discrimination is accomplished using a compact reverse Differential Mobility Analyzer (rDMA). Particle charging is accomplished using corona ionization. Concentration measurements are completed using a unique flexible printed circuit board electrode which can be removed for cleaning, disposal or chemical analysis of collected particles at the end of its in situ measurement life.
FILED	Wednesday, October 20, 2010
APPL NO	12/908280
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Measuring and testing 073/28.20
VIEW PATENT	@ USPTO: Full Text PDF

08744651 — Method of determining a maneuver performed by an aircraft

US 08744651	Bates et al.
FUNDED BY	Department of Transportation (USDOT) Federal Aviation Administration (FAA)
APPLICANT(S)	Preston R. Bates (Fort Worth, Texas); Mark W. Davis (Southbury, Connecticut); James Peter Cycon (Media, Pennsylvania); Payman Sadegh (Arlington, Virginia)
ASSIGNEE(S)	Sikorsky Aircraft Corporation (Stratford, Connecticut)
INVENTOR(S)	Preston R. Bates (Fort Worth, Texas); Mark W. Davis (Southbury, Connecticut); James Peter Cycon (Media, Pennsylvania); Payman Sadegh (Arlington, Virginia)
ABSTRACT	A method of determining a maneuver performed by an aircraft having sensors for monitoring motion data, the method including periodically sampling the sensors to electronically determine segments of motion data of the aircraft; aggregating sequences of the segments of the motion data; comparing the aggregated segments of motion data to models of particular maneuvers; and determining the maneuver performed by the aircraft.
FILED	Friday, February 18, 2011
APPL NO	13/030582
ART UNIT	3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC	Data processing: Vehicles, navigation, and relative location 71/14
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

08741663 — Enhanced detection sensitivity with piezoelectric sensors

US 08741663	Shih et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) U.S. State Government Commonwealth of Pennsylvania
APPLICANT(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (San Jose, California)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Wan Y. Shih (Bryn Mawr, Pennsylvania); Wei-Heng Shih (Bryn Mawr, Pennsylvania); Qing Zhu (San Jose, California)
ABSTRACT	A method for enhancing the detection sensitivity of a piezoelectric microcantilever sensor. The method may involve providing a piezoelectric microcantilever and inducing a change in the Young's modulus during detection of a species of interest. The change in the Young's modulus may be induced or enhanced by the application of a DC bias electric field to the piezoelectric layer that enhances non-180° polarization domain switching of the piezoelectric layer. The change in the Young's modulus may also result from binding of the species of interest to the piezoelectric microcantilever sensor or a combination of binding and application of a DC bias electric field Significantly enhanced detection sensitivity results from the changed Young's modulus of the piezoelectric layer.
FILED	Wednesday, March 04, 2009
APPL NO	12/921756
ART UNIT	1677 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemistry: Analytical and immunological testing 436/524
VIEW PATENT	@ USPTO: Full Text PDF

08743109 — System and methods for multi-dimensional rendering and display of full volumetric data sets

US 08743109	Blank et al.
FUNDED BY	U.S. State Government State of Ohio
APPLICANT(S)	James Blank (Kent, Ohio); Robert Clements (Stow, Ohio)
ASSIGNEE(S)	Kent State University (Kent, Ohio)
INVENTOR(S)	James Blank (Kent, Ohio); Robert Clements (Stow, Ohio)
ABSTRACT	A stand-alone platform and a method for the multi-dimensional rendering, display, manipulation, and analysis of full high resolution volumetric data sets. The systems and methods provide the ability to volumetrically render images with extremely high resolution in applications such as medical imaging procedures, digital microscopy such as in use of a confocal microscope, and other areas where extremely large data sets are produced from the imaging process. Certain embodiments of the system and methods produce left and right eye images of the rendered data, for viewing in parallax via a synchronized headset, and the ability to manipulate the data and display of image data easily and in real time.
FILED	Thursday, August 30, 2007
APPL NO	11/847919
ART UNIT	2614 — Electrical Circuits and Systems
CURRENT CPC	Computer graphics processing and selective visual display systems 345/419
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Department of Commerce (DOC)

08742334 — Spinning cell device for fast standardization in laser ablation inductively coupled plasma spectrometry

US 08742334	Molloy et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	John L. Molloy (Gaithersburg, Maryland); Naomi Bier (Houston, Texas); Fanny Claverie (Pau, France); Julien F. C. Malherbe (Pau, France)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Commerce, the National Institute of Standards and Technology (Washington, District of Columbia)
INVENTOR(S)	John L. Molloy (Gaithersburg, Maryland); Naomi Bier (Houston, Texas); Fanny Claverie (Pau, France); Julien F. C. Malherbe (Pau, France)
ABSTRACT	A spinning cell device is described for fast and convenient standardization and analysis of constituents and isotopes in solid samples by laser ablation inductively coupled plasma (LA-ICP) spectrometry. The method and apparatus for performing the method require the sample under test and a standard to be spun during ablation allowing the quasi-simultaneous ablation of both materials. The aerosols resulting from the ablation of sample and standard are mixed in the ablation cell allowing quantification of the ablated metals by the method of standard addition or isotope dilution. The relative proportion of standard verses sample ablated can be changed by altering the trajectory of the laser beam. The ablated aerosol is swept into an inductively coupled plasma by a carrier gas and analyzed by mass spectrometry.
FILED	Friday, April 19, 2013
APPL NO	13/867012
ART UNIT	2881 — Optics
CURRENT CPC	Radiant energy 250/282
VIEW PATENT	@ USPTO: Full Text PDF

Department of Education (ED)

08740818 — Method and apparatus for characterization of clot formation

US 08740818	Walker et al.
FUNDED BY	Department of Education (ED)
APPLICANT(S)	William F. Walker (Earlysville, Virginia); Michael B. Lawrence (Charlottesville, Virginia); Francesco Viola (Charlottesville, Virginia); Margaret Kramer Sande (Denver, Colorado)
ASSIGNEE(S)	Hemosonics, LLC (Charlottesville, Virginia)
INVENTOR(S)	William F. Walker (Earlysville, Virginia); Michael B. Lawrence (Charlottesville, Virginia); Francesco Viola (Charlottesville, Virginia); Margaret Kramer Sande (Denver, Colorado)
ABSTRACT	Methods, apparatus and systems for characterizing changes in at least one physical property of soft tissue. A series of acoustic pulses is generated and directed into the soft tissue such that at least one of the pulses is of sufficiently high intensity to induce physical displacement of the tissue. Waves reflected off the tissue, or a flexible member that moves with the tissue, are received and measured to estimate at least one characteristic of the physical displacement induced thereby. Repetition of the generating, receiving and estimating steps provides characterization of the at least one physical property over time. Methods, apparatus and systems for characterizing at least one physical property of blood, by generating a series of acoustic pulses and directing the series of pulses into the blood such that at least one of the pulses is of sufficiently high intensity to induce physical displacement of the blood. Acoustic pulses and/or optical waves reflected from the blood, or a flexible member in contact with the blood that moves with the blood, are received and measured to estimate at least one characteristic of the physical displacement induced thereby.
FILED	Thursday, October 21, 2010
APPL NO	12/909600
ART UNIT	3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Surgery 6/587
VIEW PATENT	@ USPTO: Full Text PDF

Environmental Protection Agency (EPA)

08741074 — Chemical conversion coatings for corrosion protection of copper and other alloys in contaminated water

US 08741074	Ding et al.
FUNDED BY	Environmental Protection Agency (EPA)
APPLICANT(S)	Hongbo Ding (Bridgewater, New Jersey); Jiong Liu (East Brunswick, New Jersey)
ASSIGNEE(S)	NEI Corporation (Somerset, New Jersey)
INVENTOR(S)	Hongbo Ding (Bridgewater, New Jersey); Jiong Liu (East Brunswick, New Jersey)
ABSTRACT	A non-chromate conversion coating for copper or other alloys. The conversion coating is composed of hydrotalcite-like compound (HTlcs). The conversion coating adheres well with the alloys, and provides excellent corrosion protection. In addition, corrosion inhibitive species were incorporated into the coating. The coating with inhibitors incorporated showed damage-responsive properties. The corrosion protection property of the conversion coating was further enhanced through applying a surface sealer. The coating has applicability in industrial heat exchangers that use reclaimed water.
FILED	Monday, January 31, 2011
APPL NO	13/017625
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Metal treatment 148/282
VIEW PATENT	@ USPTO: Full Text PDF

National Reconnaissance Office (NRO)

08744224 — Tapered fiber bundle apparatus with monitoring capability

US 08744224	Wysocki
FUNDED BY	National Aeronautics and Space Administration (NASA) National Reconnaissance Office (NRO)
APPLICANT(S)	Paul F. Wysocki (Flemington, New Jersey)
ASSIGNEE(S)	Alcatel Lucent (Paris, France)
INVENTOR(S)	Paul F. Wysocki (Flemington, New Jersey)
ABSTRACT	Systems and methods for monitoring signals in an optical fiber amplifier system are provided. The optical amplifier system includes a tapered fiber bundle which couples optical energy into the cladding of an optical amplifier. A signal passing through the optical amplifier is amplified. To monitor the amplified signal, a single fiber of a tapered fiber bundle may be used as a monitor fiber. Alternatively, a monitor or coupler may be integrated into the tapered fiber bundle during manufacturing. The systems and methods disclosed allow for monitoring the amplified signal without increasing the length of the amplified signal's path, thus minimizing the introduction of additional non-linearities.
FILED	Tuesday, March 07, 2006
APPL NO	11/369364
ART UNIT	2874 — Optics
CURRENT CPC	Optical waveguides 385/43
VIEW PATENT	@ USPTO: Full Text PDF

Small Business Administration (SBA)

08740618 — Braille module with compressible pin arrays

US 08740618	Shaw
FUNDED BY	National Science Foundation (NSF) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Keith N. Shaw (Gloucester, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Keith N. Shaw (Gloucester, Massachusetts)
ABSTRACT	A refreshable tactile reader apparatus for Braille text and graphics, utilizing a plurality of compressible tactile pins that can absorb strong downward forces. Such strong forces transmitted through tactile pins can damage pin actuation mechanisms. The physical enclosure of the reader provides open channels that allow the apparatus to be more easily cleaned than prior art enablements.
FILED	Friday, July 20, 2007
APPL NO	11/880360
ART UNIT	3715 — Amusement and Education Devices
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 21/003 (20130101) G09B 21/004 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

08742928 — Integrated document holder and RFID tag

US 08742928	Weller et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	John Charles Weller (Clear Brook, Virginia); Clayton Craig Bonnell (Fairfax, Virginia)
ASSIGNEE(S)	United States Postal Service (Washington, District of Columbia)
INVENTOR(S)	John Charles Weller (Clear Brook, Virginia); Clayton Craig Bonnell (Fairfax, Virginia)
ABSTRACT	An integrated document holder and RFID tag device is disclosed herein. The document holder may take the form of a shipping envelope which is affixed to an item and carries documents related to the item such as a packing list or shipping manifest. The device includes an RFID tag integrated into the shipping envelope which allows both the RFID tag and the shipping envelope to be affixed to the item in a single labor effort.
FILED	Monday, April 11, 2011
APPL NO	13/084487
ART UNIT	2684 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC	Communications: Electrical 340/572.100
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

08739343 — Fenders for pier protection against vessel collision

US 08739343	Voyiadjis et al.
FUNDED BY
APPLICANT(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S)	Board of Supervisors of Louisiana State University and Agricultural and Mechanics College (Baton Rouge, Louisiana)
INVENTOR(S)	George Z. Voyiadjis (Baton Rouge, Louisiana); Sherif El-Tawil (Ann Arbor, Michigan)
ABSTRACT	A system is disclosed for protecting supporting structures, such as those of a bridge or other such marine supporting structure, from the force of an impact of a vehicle/vessel. Such a system includes a plurality of modular components arranged in series and configured to dissipate the energy of the force through the progressive buckling of one or more of the modular components. Each modular component contains an energy dissipation unit that includes a plurality of adjacent cells. The energy of the force is dissipated in the buckling of the walls of the cells of the energy dissipation units through the formation of one or more plastic hinges and/or volume reduction of the cells.
FILED	Monday, June 03, 2013
APPL NO	13/908236
ART UNIT	3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC	Construction of Bridges, or Viaducts; Assembly of Bridges E01D 19/02 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

08741812 — Class of sterol ligands and their uses in regulation of cholesterol and gene expression

US 08741812	Javitt
FUNDED BY
APPLICANT(S)	Norman B. Javitt (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Norman B. Javitt (New York, New York)
ABSTRACT	This invention relates to novel physiological oxysteroids and oxysteroid hormones which are C27 modified sterols, particularly derivatives of intermediates in cholesterol synthesis, including lanosterol, zymosterol and desmosterol, including C27 diol and C27 acid derivatives, as well as related compounds and analogs thereof. The invention relates to treatment of cholesterol-related conditions by modulating the rate of cholesterol synthesis or cholesterol metabolism by administration of the oxysteroids, analogs or antagonists thereof. Methods are provided for ameliorating, treating or preventing macular degeneration by administering an agent which stimulates the expression or activity of steroid sulphotransferase (SLUT2), particularly SLUT2B1b, or which stimulates the expression or activity of CYP27A1 or sterol 27-hydroxylase. Assays for identification of analogs, antagonists or modulators of the oxysteroids or of sterol 27-hydroxylase are provided.
FILED	Thursday, August 25, 2005
APPL NO	11/212031
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 49/00 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

08742468 — Systems, methods and apparatus of a low conductance silicon micro-leak for mass spectrometer inlet

US 08742468	Harpold et al.
FUNDED BY
APPLICANT(S)	Dan N. Harpold (Beltsville, Maryland); Hasso B. Niemann (Columbia, Maryland); Brian G. Jamieson (Severna Park, Maryland); Bernard A. Lynch (San Antonio, Texas)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics Space Administration (Washington, District of Columbia)
INVENTOR(S)	Dan N. Harpold (Beltsville, Maryland); Hasso B. Niemann (Columbia, Maryland); Brian G. Jamieson (Severna Park, Maryland); Bernard A. Lynch (San Antonio, Texas)
ABSTRACT	Systems, methods and apparatus are provided through which in some embodiments a mass spectrometer micro-leak includes a number of channels fabricated by semiconductor processing tools and that includes a number of inlet holes that provide access to the channels.
FILED	Thursday, September 23, 2010
APPL NO	12/888973
ART UNIT	1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Active solid-state devices 257/241
VIEW PATENT	@ USPTO: Full Text PDF

08742965 — Inherently monotonic high resolution digital to analog converter

US 08742965	Cosand
FUNDED BY
APPLICANT(S)	Albert E. Cosand (Agoura Hills, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Albert E. Cosand (Agoura Hills, California)
ABSTRACT	Apparatus implementing a monotonic output digital to analog converter (DAC). A high resolution monotonic DAC may be built from a lower resolution DAC using weighting functions that combine the outputs of the lower resolution DAC such that monotonicity is maintained across major carry transitions. The lower resolution DAC should have a true output and a complementary output with a half LSB bias in the output. An extended resolution DAC may be built of; cascaded low resolution DACs; a low resolution DAC in a recursive arrangement with an intermediate storage of its output; or a low resolution DAC with weighting functions that adjust at each of several major carry transition.
FILED	Thursday, April 12, 2012
APPL NO	13/401979
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coded data generation or conversion 341/144
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 03, 2014.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140603.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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