FedInvent™ Patents

Patent Details for Tuesday, June 10, 2014 

This page was updated on Monday, March 27, 2023 at 04:01 AM GMT

Department of Health and Human Services (HHS) 

US 08746999 Davis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Mark E. Davis (Pasadena, California);  Akinleye Alabi (Cambridge, Massachusetts)
ABSTRACT Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems.
FILED Thursday, March 28, 2013
APPL NO 13/852397
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Typewriting machines
4/489
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747294 Lipari et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Christopher William Lipari (Jacksonville, Florida);  Annabelle Rodriguez (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Christopher William Lipari (Jacksonville, Florida);  Annabelle Rodriguez (Baltimore, Maryland)
ABSTRACT The present invention relates, e.g., to a method for predicting the embryonic progression of a preimplantation embryo, comprising measuring in the insemination medium (IM) in which an oocyte was fertilized and subsequently incubated in vitro, thereby generating a pre-implantation embryo, at 18-24 hrs post fertilization, the levels of nitric oxide metabolites (NOx) in the insemination medium (IM), wherein a level of NOx of at least about 1.3 μM indicates that the preimplantation embryo is likely to progress to the blastocyst stage by culture day (CD) 5.
FILED Friday, October 31, 2008
APPL NO 12/740800
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/435 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747382 D'Souza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Warren D'Souza (Timonium, Maryland);  Hao Zhang (Baltimore, Maryland);  Kathleen Malinowski (Annapolis, Maryland)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland);  University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Warren D'Souza (Timonium, Maryland);  Hao Zhang (Baltimore, Maryland);  Kathleen Malinowski (Annapolis, Maryland)
ABSTRACT One embodiment includes a method of predicting a position of a target site inside a body using surrogates is provided. The method includes transforming surrogate measurements and target positions into different representations by applying an operator, establishing a special relationship between the transformed surrogate measurements and the transformed target positions, and continuously predicting the target position from the transformed surrogate measurements and the established special relationship.
FILED Wednesday, June 29, 2011
APPL NO 13/172010
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
64/500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747669 Bonner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Alex G. Bonner (Lexington, Massachusetts);  Gaston de los Reyes (Somerville, Massachusetts)
ASSIGNEE(S) SPF Innovations, LLC (Somerville, Massachusetts)
INVENTOR(S) Alex G. Bonner (Lexington, Massachusetts);  Gaston de los Reyes (Somerville, Massachusetts)
ABSTRACT A separation module and method are disclosed for processing a liquid sample and providing high conversion by operating a single-pass tangential-flow process without a recirculation loop. In one embodiment, the separation module includes three reservoirs and has at least one long, thin channel with a large ratio of channel membrane area to: channel void volume; volume of a sample feed reservoir; and volume of the feed sample. In another embodiment, the separation module includes an external feed reservoir, an external retentate reservoir fluidly and a first vacuum source adapted to apply a first vacuum to the separation element disposed within the housing. The single-pass TFF separation element and single-pass process provides high conversion while operating with relatively low pressure sources. Certain embodiments disclosed herein can be used for the separation of blood.
FILED Sunday, August 15, 2010
APPL NO 12/856677
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/321.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747801 Bowers et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Michael J. Bowers (Nashville, Tennessee);  James R. McBride (Nashville, Tennessee);  Sandra J. Rosenthal (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Michael J. Bowers (Nashville, Tennessee);  James R. McBride (Nashville, Tennessee);  Sandra J. Rosenthal (Nashville, Tennessee)
ABSTRACT Disclosed herein are methods of preparing inorganic nanoparticles. In one aspect, the methods can comprise heating a reaction mixture comprising a C8 to C20 alkyl- or arylphosphonic acid and a source of cadmium or zinc to a temperature of greater than about 300° C.; adding to the reaction mixture an injection mixture comprising a C2 to C16 trialkyl- or triarylphosphine and a source of selenium, sulfur, or tellurium; and decreasing the temperature of the reaction mixture to less than about 300° C. Also disclosed herein are nanoparticles made from the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, November 16, 2012
APPL NO 13/679924
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/509
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747810 Mahmood et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Ashfaq Mahmood (Newton Center, Massachusetts);  Alun G. Jones (Newton Center, Massachusetts);  Naengnoi Limpa-Amara (Cambridge, Massachusetts);  Yijie Peng (Belmont, Massachusetts);  Zeynep Akgun (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Ashfaq Mahmood (Newton Center, Massachusetts);  Alun G. Jones (Newton Center, Massachusetts);  Naengnoi Limpa-Amara (Cambridge, Massachusetts);  Yijie Peng (Belmont, Massachusetts);  Zeynep Akgun (Boston, Massachusetts)
ABSTRACT The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled metal complexes, particularly tissues, organs, or tumors which express certain receptors to which the compounds or complexes of the invention have an affinity. The present invention also relates to methods of treating cancer, particularly those cancer lines which express certain receptors to which the compounds or complexes of the invention have an affinity. In yet another embodiment, the present invention provides methods of imaging and/or inhibiting receptors or neuroreceptors using compounds or complexes of the invention which have an affinity for the receptor or neuroreceptor to be imaged and/or inhibited.
FILED Tuesday, December 13, 2011
APPL NO 13/325051
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0002 (20130101) Original (OR) Class
A61K 51/02 (20130101)
A61K 51/04 (20130101)
A61K 2123/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747843 Giroir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Brett P. Giroir (Vienna, Virginia);  Monte S. Willis (Chapel Hill, North Carolina);  Vidal F. De La Cruz, Jr. (Phoenixville, Pennsylvania);  Thais M. Sielecki-Dzurdz (Kennett Square, Pennsylvania)
ASSIGNEE(S) Baxter International, Inc. (Deerfield, Illinois);  Baxter Healthcare SA (Glattpark, Opfikon, Switzerland);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Brett P. Giroir (Vienna, Virginia);  Monte S. Willis (Chapel Hill, North Carolina);  Vidal F. De La Cruz, Jr. (Phoenixville, Pennsylvania);  Thais M. Sielecki-Dzurdz (Kennett Square, Pennsylvania)
ABSTRACT One embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount of at least one anti-MIF antibody; and at least one pharmaceutically acceptable carrier. Another embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount at least one anti-CD74 antibody; and at least one pharmaceutically acceptable carrier. Another embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount of at least one anti-TNFR antibody; a therapeutically effective amount of at least one anti-MIF antibody; and at least one pharmaceutically acceptable carrier. Other embodiments of the present invention relate to methods of treating or preventing cardiac dysfunction, cardiodepression, burn injury-associated cardiac dysfunction, improving cardiac function in a subject following acute myocardial infarction, and identifying an MIF inhibitor.
FILED Wednesday, October 31, 2007
APPL NO 11/932909
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747844 Salvemini
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Daniela Salvemini (Chesterfield, Missouri)
ASSIGNEE(S) Saint Louis University (St. Louis, Missouri)
INVENTOR(S) Daniela Salvemini (Chesterfield, Missouri)
ABSTRACT The invention relates to methods for treating pain disorders including neuropathic and inflammatory pain and to methods to reduce or eliminate nociceptive tolerance induced by opiate analgesic use by administering an agent that suppresses or blocks S1P biological activity.
FILED Monday, July 25, 2011
APPL NO 13/189954
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
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US 08747846 Spellberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
U.S. Public Health Service (USPHS)
APPLICANT(S) Brad J. Spellberg (Rancho Palos Verdes, California);  Lin Lin (Rancho Palos Verdes, California);  Ashraf Ibrahim (Irvine, California);  Guanpingsheng Luo (Torrance, California)
ASSIGNEE(S) Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (Torrance, California)
INVENTOR(S) Brad J. Spellberg (Rancho Palos Verdes, California);  Lin Lin (Rancho Palos Verdes, California);  Ashraf Ibrahim (Irvine, California);  Guanpingsheng Luo (Torrance, California)
ABSTRACT The present invention provides vaccine compositions comprising OmpA, or antigenic fragments thereof, and related methods of active immunization against A. baumannii infection. The invention also provides antibodies and antigen-binding parts thereof that specifically bind to OmpA, and related methods of passive immunization against A. baumannii infection. The compositions and methods of the invention are useful for preventing or treating A. baumannii infections, including those caused by strains resistant to carbapenems and all other antibiotics except colistin or tigecycline, also referred to as extreme drug resistant (XDR) A. baumannii infections, and those resistant to every FDA approved antibiotic, also referred to as pan-drug resistant (PDR) A. baumannii infections.
FILED Friday, May 11, 2012
APPL NO 13/470177
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747860 Rosenberger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Carrie M. Rosenberger (San Francisco, California);  Alan A. Aderem (Seattle, Washington)
ASSIGNEE(S) Institute for Systems Biology (Seattle, Washington)
INVENTOR(S) Carrie M. Rosenberger (San Francisco, California);  Alan A. Aderem (Seattle, Washington)
ABSTRACT The invention is directed to an improved method to manufacture virus for use in vaccine by culturing infected cells that have been modified to overexpress miR-144. The invention is also directed to manipulating the activity or level of miR-144 in subjects in order to modulate the antiviral and immune response systems.
FILED Thursday, July 05, 2012
APPL NO 13/542581
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/204.100
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US 08747863 Robbins et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) John B. Robbins (New York, New York);  Rachel Schneerson (Bethesda, Maryland);  Joanna Kubler-Kielb (Bethesda, Maryland);  Christopher P. Mocca (Columbia, Maryland);  Evguenii Vinogradov (Ottawa, Canada)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  National Research Council of Canada (Ottawa, Canada)
INVENTOR(S) John B. Robbins (New York, New York);  Rachel Schneerson (Bethesda, Maryland);  Joanna Kubler-Kielb (Bethesda, Maryland);  Christopher P. Mocca (Columbia, Maryland);  Evguenii Vinogradov (Ottawa, Canada)
ABSTRACT Disclosed are immunogenic conjugates and therapeutic compositions that include such immunogenic conjugates. Also disclosed are methods of treating and/or inhibiting an Shigella sonnei infection. The disclosed immunogenic conjugates have the general structure:
Pr—Sr—O—N═C-Kdo-OS
wherein Pr is a carrier protein, Sr is an optional spacer moiety, Kdo is an 3-deoxy-D-manno-octulosonic acid or a derivative thereof, and OS is an oligosaccharide or polysaccharide obtained from S. sonnei. In specific examples, the immunogenic conjugates include the core oligosaccharide obtained from S. sonnei having the structure: wherein R is between 1 and 10 disaccharide repeat units. In specific examples, the disaccharide repeat unit included in the immunogenic conjugate has the structure:
α-L-AltNAcA-3-β-FucNAc4N-4-.
FILED Friday, August 14, 2009
APPL NO 13/059051
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/02 (20130101) Original (OR) Class
A61K 39/385 (20130101)
A61K 47/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747869 Irvine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Darrell J. Irvine (Arlington, Massachusetts);  Jaehyun Moon (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Darrell J. Irvine (Arlington, Massachusetts);  Jaehyun Moon (Cambridge, Massachusetts)
ABSTRACT The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
FILED Saturday, March 19, 2011
APPL NO 13/052067
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101) Original (OR) Class
A61K 9/1273 (20130101)
A61K 2039/55572 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747870 Gupta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Kavita Gupta (Salt Lake City, Utah);  Meredith R. Clark (Bethesda, Maryland);  Patrick F. Kiser (Chicago, Illinois);  Julie I. Jay (Salt Lake City, Utah)
ABSTRACT Described herein are polymeric compositions that comprise at least one polymer residue and at least one crosslinking moiety, wherein the polymer residue is crosslinked by the crosslinking moiety and wherein the crosslinking moiety is formed from a reaction between a boronic acid moiety and a hydroxamic acid moiety. Also, described are methods of making and using such polymeric compositions.
FILED Wednesday, January 16, 2013
APPL NO 13/742877
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/400
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US 08747905 Yoon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Young-Sup Yoon (Atlanta, Georgia);  Hyun-Jai Cho (Seoul, South Korea)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Young-Sup Yoon (Atlanta, Georgia);  Hyun-Jai Cho (Seoul, South Korea)
ABSTRACT As described below, the present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells.
FILED Monday, October 29, 2007
APPL NO 12/447180
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/577
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747907 Rzigalinski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Beverly A. Rzigalinski (Radford, Virginia);  Ariane M. Clark (Bradenton, Florida)
ASSIGNEE(S)
INVENTOR(S) Beverly A. Rzigalinski (Radford, Virginia);  Ariane M. Clark (Bradenton, Florida)
ABSTRACT The present invention provides cerium oxide nanoparticles for use both in therapeutic compositions in vivo and in research in vitro. The cerium oxide nanoparticles are of known range of sizes having biological properties that are reproducible and beneficial. Pharmaceutical and other compositions are provided, as are methods of treatment.
FILED Monday, July 02, 2012
APPL NO 13/539564
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/617
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US 08747924 Pasinetti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Complementary and Integrative Health (NCCIH)
APPLICANT(S) Giulio Maria Pasinetti (New York, New York);  Lap Ho (New York, New York);  Jun Wang (Flushing, New York)
ASSIGNEE(S) Icahn School of Medicine At Mount Sinai (New York, New York)
INVENTOR(S) Giulio Maria Pasinetti (New York, New York);  Lap Ho (New York, New York);  Jun Wang (Flushing, New York)
ABSTRACT The present invention provide a method for the prevention and treatment of a neurodegenerative disease including Alzheimer's Disease, Huntington's Disease, and Parkinson's Disease, using a grape seed extract or one or more compounds derived therefrom. In particular, the present invention provides a method to treat a patient diagnosed with, or at the risk of developing, a neurodegenerative disease by administering a pharmaceutical composition comprising a grape seed extract or one or more compounds derived therefrom to the patient in a therapeutic amount to reduce the accumulation, aggregation or deposition of amyloid beta or its oligomers, and/or to reduce the misfolding, accumulation and/or aggregation of tau proteins or other proteins.
FILED Tuesday, November 09, 2010
APPL NO 12/942785
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/766
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748085 Pai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Jeng-Hao Pai (Chapel Hill, North Carolina);  Yuli Wang (Cary, North Carolina);  Christopher E. Sims (Chapel Hill, North Carolina);  Mark Bachman (Irvine, California);  Nancy Allbritton (Chapel Hill, North Carolina);  Guann-Pyng Li (Irvine, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jeng-Hao Pai (Chapel Hill, North Carolina);  Yuli Wang (Cary, North Carolina);  Christopher E. Sims (Chapel Hill, North Carolina);  Mark Bachman (Irvine, California);  Nancy Allbritton (Chapel Hill, North Carolina);  Guann-Pyng Li (Irvine, California)
ABSTRACT Systems and methods directed to the use 1002F to build microdevices and biomedical devices. Through the addition of a photosensitizing agent, Epon epoxy resin 1002F can be linked in the presence of UV light, making it useful as a photoresist or as a micropatternable structural material. One embodiment comprises combining 1002F monomer resin with a solvent and a photoinitiator, placing the monomer solution on a surface, exposing the monomer solution to UV light through a mask to initiate linking, and stripping the unlinked polymer away. In another embodiment, 3-D structures are built using two or more layers of sensitized monomer films, each having different sensitivity to light, and the use of a mask containing opaque and semi-opaque regions.
FILED Friday, July 25, 2008
APPL NO 12/670349
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Radiation imagery chemistry: Process, composition, or product thereof
430/322
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748089 Kariko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Katalin Kariko (Rydal, Pennsylvania);  Drew Weissman (Wynnewood, Pennsylvania)
ABSTRACT This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.
FILED Friday, March 15, 2013
APPL NO 13/839155
ART UNIT 1674 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
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US 08748091 Timp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) Gregory Timp (South Bend, Indiana);  Winston Timp (Baltimore, Maryland);  Utkur Mirsaidov (Urbana, Illinois);  Aleksei Aksimentiev (Urbana, Illinois);  Jeffrey Comer (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The John Hopkins University (Baltimore, Maryland)
INVENTOR(S) Gregory Timp (South Bend, Indiana);  Winston Timp (Baltimore, Maryland);  Utkur Mirsaidov (Urbana, Illinois);  Aleksei Aksimentiev (Urbana, Illinois);  Jeffrey Comer (Urbana, Illinois)
ABSTRACT Methods of trapping a deformed portion of a double-stranded polynucleotide in a membrane nanopassage are provided. In an aspect, the membrane has a nanopassage that defines a confine region, wherein the membrane separates a first fluid compartment from a second fluid compartment, and the nanopassage is in fluid communication with the first and second compartments. A polynucleotide is provided to the first fluid compartment and optionally a threshold voltage for the membrane and the polynucleotide is determined. A driving voltage across the membrane that is greater than the threshold voltage is applied to force a portion of the polynucleotide sequence into the nanopassage confine region, and decreased to a holding voltage bias to trap the polynucleotide portion in the nanopassage confine region. In particular, at least one nucleotide base-pair is fixably positioned in the nanopassage confine volume. In further embodiments, any of the trapping methods are used to characterize or sequence double stranded DNA.
FILED Friday, December 17, 2010
APPL NO 12/971240
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4146 (20130101)
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US 08748096 Ranum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Laura P. W. Ranum (St. Paul, Minnesota);  Michael D. Koob (Roseville, Minnesota);  Kellie A. Benzow (Plymouth, Minnesota);  Melinda L. Moseley-Alldredge (St. Paul, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Laura P. W. Ranum (St. Paul, Minnesota);  Michael D. Koob (Roseville, Minnesota);  Kellie A. Benzow (Plymouth, Minnesota);  Melinda L. Moseley-Alldredge (St. Paul, Minnesota)
ABSTRACT The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
FILED Monday, August 20, 2012
APPL NO 13/589266
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748098 Hernando et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Eva Hernando (New York, New York);  Miguel Segura (New York, New York);  Douglas Hanniford (New York, New York);  Silvia Menendez (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Eva Hernando (New York, New York);  Miguel Segura (New York, New York);  Douglas Hanniford (New York, New York);  Silvia Menendez (New York, New York)
ABSTRACT Described herein are compositions and methods for the diagnosis, prognosis, prevention and treatment of melanoma or melanoma associated symptoms. The compositions are microRNA molecules associated with melanoma, as well as various nucleic acid molecules relating thereto or derived therefrom.
FILED Wednesday, August 08, 2012
APPL NO 13/569845
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748106 Singh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Bal Ram Singh (N. Dartmouth, Massachusetts);  Yu Zhou (New Bedford, Massachusetts)
ASSIGNEE(S) Bal Ram Singh (North Dartmouth, Massachusetts)
INVENTOR(S) Bal Ram Singh (N. Dartmouth, Massachusetts);  Yu Zhou (New Bedford, Massachusetts)
ABSTRACT This application is based, inter alia, on the discovery of a binding interaction between the Hn-33 hemagglutinin polypeptide of the type A Clostridium botulinum neurotoxin complex and synaptosomal proteins, including synaptotagmin II (Syt II). Methods of screening for compounds that modulate, e.g., increase or decrease, this interaction are provided. Also provided are compositions and methods for targeting compounds to neuronal and cancer cells by coupling the compounds to Hn-33 or biologically active Hn-33 variants.
FILED Tuesday, April 18, 2006
APPL NO 11/911889
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748113 Matsui et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) William Matsui (Baltimore, Maryland);  Richard J. Jones (Baltimore, Maryland);  Carol A. Huff (Ellicott City, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) William Matsui (Baltimore, Maryland);  Richard J. Jones (Baltimore, Maryland);  Carol A. Huff (Ellicott City, Maryland)
ABSTRACT Provided herein are compositions, methods, and kits useful for detecting whether a subject has or is likely to develop a cancer and for monitoring, staging and examining a cancer patient. Also provide herein are methods for screening compounds.
FILED Wednesday, November 12, 2008
APPL NO 12/743180
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748114 Staudt et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Louis M. Staudt (Silver Spring, Maryland);  Andreas Rosenwald (Bethesda, Maryland);  Wyndham Wilson (Washington, District of Columbia);  Todd S. Barry (Seattle, Washington);  Adrian Wiestner (Bethesda, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Louis M. Staudt (Silver Spring, Maryland);  Andreas Rosenwald (Bethesda, Maryland);  Wyndham Wilson (Washington, District of Columbia);  Todd S. Barry (Seattle, Washington);  Adrian Wiestner (Bethesda, Maryland)
ABSTRACT It has been surprisingly found that ZAP-70 expression, both at the protein and mRNA levels, is indicative of clinical subgroups of CLL/SLL patients. In particular, high ZAP-70 expression is indicative of Ig-unmutated CLL/SLL. Methods are provided for discriminating between clinical subgroups of CLL/SLL, by determining whether subjects overexpress ZAP-70 mRNA or protein.
FILED Tuesday, June 07, 2011
APPL NO 13/155198
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748116 Lee
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Brigham and Women s Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Richard T. Lee (Weston, Massachusetts)
ABSTRACT This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure.
FILED Thursday, March 07, 2013
APPL NO 13/788276
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748119 Gooch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Jennifer L. Gooch (Lilburn, Georgia);  Brian R. Roberts (Sandy Springs, Georgia);  Jan Pohl (Tucker, Georgia)
ABSTRACT One aspect of the present disclosure encompasses methods for determining a protein kinase or phosphatase activity in a biological sample, comprising: contacting in a reaction mix a first test sample and a fluorescently-labeled peptide substrate capable of being modified by a protein phosphatase or a protein kinase, contacting the reaction mix with a TiO2 matrix, thereby partitioning fluorescently-labeled phosphorylated peptide from fluorescently-labeled dephosphorylated peptide; and determining the fluorescence of the fluorescently-labeled dephosphorylated peptide, thereby determining a protein kinase or phosphatase activity.
FILED Thursday, December 06, 2012
APPL NO 13/706750
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/21
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748121 Blair et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Ian Blair (Wynnewood, Pennsylvania);  Clementina Mesaros (Philadelphia, Pennsylvania);  Wenying Jian (Princeton, New Jersey);  Seon Hwa Lee (Aoba-ku, Japan);  Tomoyuki Oe (Aoba-ku, Japan)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Ian Blair (Wynnewood, Pennsylvania);  Clementina Mesaros (Philadelphia, Pennsylvania);  Wenying Jian (Princeton, New Jersey);  Seon Hwa Lee (Aoba-ku, Japan);  Tomoyuki Oe (Aoba-ku, Japan)
ABSTRACT The invention relates to biomarkers of oxidative stress and their use. Specifically, the invention relates to thiadiazabicyclo-4-oxo-2(E)-nonenal-Glutathione adduct as a biomarker of oxidative stress and its diagnostic use.
FILED Tuesday, October 23, 2007
APPL NO 11/976316
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/29
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748165 Vangbo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Mattias Vangbo (Fremont, California);  William D. Nielsen (San Jose, California);  Iuliu I. Blaga (Fremont, California);  Michael Van Nguyen (San Diego, California);  Steven B. Jovanovich (Livermore, California)
ASSIGNEE(S) IntegenX Inc. (Pleasanton, California)
INVENTOR(S) Mattias Vangbo (Fremont, California);  William D. Nielsen (San Jose, California);  Iuliu I. Blaga (Fremont, California);  Michael Van Nguyen (San Diego, California);  Steven B. Jovanovich (Livermore, California)
ABSTRACT This invention provides a method for generating short tandem repeat (STR) profiles on each of a plurality of samples comprising, for each sample: a) isolating DNA from the sample; b) amplifying STR markers in the isolated DNA and c) analyzing the amplification product by electrophoresis.
FILED Tuesday, August 21, 2012
APPL NO 13/590965
ART UNIT 1775 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/287.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748168 Williams et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) James A. Williams (Lincoln, Nebraska);  Clague P. Hodgson (Omaha, Nebraska)
ASSIGNEE(S) Nature Technology Corp. (Lincoln, Nebraska)
INVENTOR(S) James A. Williams (Lincoln, Nebraska);  Clague P. Hodgson (Omaha, Nebraska)
ABSTRACT A general method and strains of bacteria are described, by means of which it is possible to dramatically purify plasmid DNA with respect to genomic DNA, and RNA. In one preferred embodiment, lysis and nuclease removal of host nucleic acids is an integral component of the fermentation/harvest process, and as such, achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs.
FILED Monday, August 15, 2005
APPL NO 11/573756
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748170 Finn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Olivera J. Finn (Pittsburgh, Pennsylvania);  Laura A. Vella-Geynisman (Chicago, Illinois)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Olivera J. Finn (Pittsburgh, Pennsylvania);  Laura A. Vella-Geynisman (Chicago, Illinois)
ABSTRACT In one embodiment, the invention provides a composition comprising one or more polypeptide(s), each of said polypeptide(s) comprising a sequence selected from the group consisting of KFRLLQETMYMTVSI (SEQ ID NO: 1), LQETMYMTVSIIDRF (SEQ ID NO: 2), and MYMTVSIIDRFM (SEQ ID NO: 3), or a combination of two or three such polypeptides, wherein each of said polypeptide(s) consist(s) of at most 24 amino acid residues, the composition also comprising a carrier. In another embodiment, the invention provides a composition comprising one or more bacterial or viral vectors comprising one or more nucleic acid molecule(s) encoding one or more polypeptide(s), each of said polypeptide(s) having a sequence selected from the group consisting of KFRLLQETMYMTVSI (SEQ ID NO: 1), LQETMYMTVSIIDRF (SEQ ID NO: 2), and MYMTVSIIDRFM (SEQ ID NO: 3), wherein each of said polypeptide(s) consist(s) of at most 24 amino acid residues.
FILED Monday, July 27, 2009
APPL NO 13/055907
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/320.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748171 Keller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Gordon M Keller (Toronto, Canada);  Valerie Kouskoff (Manchester, United Kingdom);  Atsushi Kubo (Nara, Japan);  Hans Joerg Fehling (Ulm, Germany)
ASSIGNEE(S) Mount Sinai School of Medicine (New York, New York)
INVENTOR(S) Gordon M Keller (Toronto, Canada);  Valerie Kouskoff (Manchester, United Kingdom);  Atsushi Kubo (Nara, Japan);  Hans Joerg Fehling (Ulm, Germany)
ABSTRACT The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
FILED Wednesday, July 14, 2010
APPL NO 12/836275
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748173 Kearney
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) John F. Kearney (Birmingham, Alabama)
ASSIGNEE(S) UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S) John F. Kearney (Birmingham, Alabama)
ABSTRACT The present invention provides monoclonal antibodies which are highly specific for Bacillus spores. Also provided are peptides derived from those monoclonal antibodies. Both the antibodies and peptides are highly specific and can discriminate between spores of potentially lethal organisms such as Bacillus anthracis and other harmless but closely related bacilli and provide a very powerful tool in the construction of detection instruments as counter measures.
FILED Friday, November 17, 2006
APPL NO 11/601133
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/340
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748192 Tian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
U.S. State Government
State of Arizona
APPLICANT(S) Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Yanqing Tian (Chandler, Arizona);  Weiwen Zhang (Chandler, Arizona);  Deirdre Meldrum (Phoenix, Arizona);  Hongguang Lu (Harbin, China PRC);  Yuguang Jin (Gilbert, Arizona);  Mark Holl (Tempe, Arizona)
ABSTRACT The present invention relates to an optical fluorescence dual sensor comprising a probe for sensing pH, a probe for sensing oxygen, an intra-reference probe and a matrix. The present invention also relates to methods of preparing an optical fluorescence dual sensor and methods of using them.
FILED Wednesday, October 24, 2012
APPL NO 13/659821
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Chemistry: Analytical and immunological testing
436/136
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748338 Luthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Richard G. Luthy (Stanford, California);  Eun Ah Kim (Menlo Park, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Richard G. Luthy (Stanford, California);  Eun Ah Kim (Menlo Park, California)
ABSTRACT A toxin immobilization particle and method of fabrication is provided that includes a polysulfide-rubber polymer coated activated carbon particle that provides enhanced toxin adsorption. A porous activated carbon particle have a size range up to 2 mm is used. The polysulfide-rubber polymer coated activated carbon particle includes a polymer-dose range of up to 1.64 grams of sulfur per gram of activated carbon particles, where the toxins can include mercury, PCBs, chlorinated pesticides or polycyclic aromatic hydrocarbons. The method of forming the toxin immobilization particle includes condensing a polymer in a sulfide mixture to form a polysulfide-rubber polymer compound and coating an activated carbon particle with the polysulfide-rubber polymer. The levels of sulfur loading in the toxin immobilization particles are controlled by the polymer dose during the coating process, where the polysulfide polymer coated activated carbon particle provides enhanced toxin adsorption.
FILED Friday, October 21, 2011
APPL NO 13/317555
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/402
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748354 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Howard Yuan-Hao Chang (Stanford, California);  Ci Chu (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Howard Yuan-Hao Chang (Stanford, California);  Ci Chu (Stanford, California)
ABSTRACT A method of sample analysis is provided. In certain cases, the method comprises: a) cross-linking the contents of a cell using a heat stable crosslinking agent to produce cross-linked ribonucleotide complexes; b) fragmenting the cross-linked ribonucleotide complexes to produce complexes comprising protein, RNA fragments and, optionally, genomic DNA fragments; c) contacting the complexes with a plurality of non-overlapping oligonucleotides comprise an affinity tag and that are complementary to a specific target RNA of the cell under high stringency conditions that include high temperature; d) isolating complexes that contain the oligonucleotides using the affinity tag to produce isolated complexes; e) enzymatically releasing the protein, RNA fragments and/or the genomic DNA fragments from the isolated complexes to produce a released component, without reversing the crosslinking; and f) analyzing the released component.
FILED Tuesday, August 07, 2012
APPL NO 13/569005
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Combinatorial chemistry technology: Method, library, apparatus
56/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748369 Epperly et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Michael W. Epperly (Pittsburgh, Pennsylvania);  Abhay Sudhir Gokhale (Galena, Ohio);  Joel S. Greenberger (Sawickley, Pennsylvania);  Peter Wipf (Pittsburgh, Pennsylvania);  Julianne Glowacki (Jamaica Plain, Massachusetts)
ASSIGNEE(S) University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Michael W. Epperly (Pittsburgh, Pennsylvania);  Abhay Sudhir Gokhale (Galena, Ohio);  Joel S. Greenberger (Sawickley, Pennsylvania);  Peter Wipf (Pittsburgh, Pennsylvania);  Julianne Glowacki (Jamaica Plain, Massachusetts)
ABSTRACT Provided herein are compositions and related methods useful for accelerating bone healing and growth. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity.
FILED Friday, June 04, 2010
APPL NO 13/320999
ART UNIT 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/1.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748372 Luban et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Jeremy Luban (New York, New York);  David Sayah (San Francisco, California)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Jeremy Luban (New York, New York);  David Sayah (San Francisco, California)
ABSTRACT The invention provides an isolated nucleic acid encoding a TRIM-cyclophilin A fusion sequence encoding a TRIMcyp fusion protein which is active as an anti-viral agent, and in particular an anti-HIV-1 agent. The invention provides for a nucleic acid encoding a polypeptide having both TRIM activity and cyclophilin activity. The invention provides for an isolated polynucleotide encoding a TRIM-cyclophilin fusion protein, or variants thereof retaining the TRIM and cyclophilin activities. The invention provides for compositions thereof, antibodies that specifically bind thereto, and vectors and host cells comprising the nucleic acid or polypeptide. In addition, the invention provides for methods for treating or preventing viral infection, or reducing viral load in a subject comprising administering the nucleic acid, polypeptide, vector, or composition to the subject in an amount effective to treat or prevent the viral infection.
FILED Tuesday, December 20, 2011
APPL NO 13/331363
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/3.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748373 Chai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Ning Chai (Philadelphia, Pennsylvania);  John M. Taylor (Cheltenham, Pennsylvania)
ASSIGNEE(S) Fox Chase Cancer Center (Philadelphia, Pennsylvania)
INVENTOR(S) Ning Chai (Philadelphia, Pennsylvania);  John M. Taylor (Cheltenham, Pennsylvania)
ABSTRACT A polypeptide comprising a preS1 region of hepatitis B virus (HBV), or a fragment thereof, and/or the preS2 region of HBV or a fragment thereof, and methods of use to inhibit virus infection are disclosed. A lentivirus comprising hepatitis B virus (HBV) envelope proteins, or a fragment thereof, and/or the L envelope protein of HBV and/or the M envelope protein of HBV or a fragment thereof, and/or the S envelope protein of HBV or a fragment thereof, and methods of use of this lentivirus HBV pseudovirus as a gene therapy to target hepatocytes for the administration of therapeutic agents are also disclosed.
FILED Wednesday, February 20, 2008
APPL NO 12/526759
ART UNIT 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/4.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748381 Polk et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) D. Brent Polk (Los Angeles, California);  Fang Yan (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) D. Brent Polk (Los Angeles, California);  Fang Yan (Nashville, Tennessee)
ABSTRACT The present invention provides therapeutic and prophylactic compositions for use in treating and preventing disorders involving epithelial cell apoptosis, such as gastrointestinal disorders (e.g., inflammatory bowel disease, Crohn's disease or ulcerative colitis) in a subject, such as a human patient.
FILED Wednesday, April 28, 2010
APPL NO 13/318010
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/16.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748385 O'Shea et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Kathy Sue O'Shea (Ann Arbor, Michigan);  Maria Morell (Granada, Spain)
ASSIGNEE(S) Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Kathy Sue O'Shea (Ann Arbor, Michigan);  Maria Morell (Granada, Spain)
ABSTRACT This disclosure describes a novel population of cerebellum-derived neural stem cells that can be isolated from the adult brain, expanded, and differentiated into neurons, astrocytes and oligodendrocytes. This disclosure also describes compositions and methods for producing oligodendrocytes. Oligodendrocytes can be produced in vitro (e.g., in culture) or in vivo (e.g., for therapy or in a non-human transgenic animal) using the compositions and methods described herein.
FILED Tuesday, June 08, 2010
APPL NO 13/375269
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/17.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748386 Sigurdsson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Einar M. Sigurdsson (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Einar M. Sigurdsson (New York, New York)
ABSTRACT The present invention relates to methods and compositions for treating, preventing, and diagnosing Alzheimer's Disease or other tauopathies in a subject by administering an immunogenic tau peptide or an antibody recognizing the immunogenic tau epitope under conditions effective to treat, prevent, or diagnose Alzheimer's Disease or other tauopathies. Also disclosed are methods of promoting clearance of aggregates from the brain of the subject and of slowing progression of tau-pathology related behavioral phenotype in a subject.
FILED Thursday, June 10, 2010
APPL NO 12/813297
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/17.800
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748390 Schlom et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Jeffrey Schlom (Potomac, Maryland);  Kwong-Yok Tsang (Bethesda, Maryland);  Ira Pastan (Potomac, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Jeffrey Schlom (Potomac, Maryland);  Kwong-Yok Tsang (Bethesda, Maryland);  Ira Pastan (Potomac, Maryland)
ABSTRACT The invention provides a peptide comprising a human cytolytic T lymphocyte (CTL) epitope from the human tumor-associated antigen (TAA) New Gene Expressed in Prostate (NGEP), which can be used in vaccine prevention or therapy of prostate cancer, as well as a nucleic acid encoding the peptide, a vector comprising the nucleic acid, a cell comprising the peptide, nucleic acid, or vector, and compositions thereof.
FILED Monday, April 19, 2010
APPL NO 13/265490
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/19.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748392 Cox, III
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) George N. Cox, III (Louisville, Colorado)
ASSIGNEE(S) Bolder BioTechnology Inc. (Boulder, Colorado)
INVENTOR(S) George N. Cox, III (Louisville, Colorado)
ABSTRACT Disclosed are cysteine variants of interleukin-11 (IL-11) and methods of making and using such proteins in therapeutic applications.
FILED Thursday, February 02, 2012
APPL NO 13/365158
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/21.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748393 Mochly-Rosen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Daria Mochly-Rosen (Menlo Park, California);  Xin Qi (Beachwood, Ohio);  Nir Qvit (Menlo Park, California)
ASSIGNEE(S) The Board of Trustees of The Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Daria Mochly-Rosen (Menlo Park, California);  Xin Qi (Beachwood, Ohio);  Nir Qvit (Menlo Park, California)
ABSTRACT The present disclosure provides peptides and constructs that inhibit mitochondrial fission, and compositions comprising the peptides or constructs. The present disclosure provides methods of reducing abnormal mitochondrial fission in a cell. Also provided are methods for designing and validating mitochondrial fission inhibitor constructs and peptides, including but not limited to, evaluating the effects of the constructs and peptides on dynamin 1-like protein (Drp1) guanosine triphosphate phosphatase (GTPase) activity, binding of Drp1 to mitochondrial fission 1 protein (Fis1), reduction of mitochondrial damage, reduction in cell death, inhibition of mitochondrial fragmentation in a cell under pathological conditions, and reduced loss of neurites in primary dopaminergic neurons in a Parkinsonism cell culture.
FILED Monday, May 14, 2012
APPL NO 13/471221
ART UNIT 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/16 (20130101) Original (OR) Class
A61K 51/08 (20130101)

Peptides
C07K 14/00 (20130101)
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748403 Kurt-Jones et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Evelyn A. Kurt-Jones (Belmont, Massachusetts);  Robert W. Finberg (Sudbury, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Evelyn A. Kurt-Jones (Belmont, Massachusetts);  Robert W. Finberg (Sudbury, Massachusetts)
ABSTRACT Toll-like receptor 2 (TLR2) has been found to mediate certain effects of HSV infection, particularly in neonates. Compounds that decrease TLR2 expression or activity are useful for ameliorating such deleterious effects.
FILED Friday, January 21, 2005
APPL NO 11/041065
ART UNIT 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748404 Steinman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Lawrence Steinman (Palo Alto, California);  Pedro Ruiz (Menlo Park, California);  Hideki Garren (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Lawrence Steinman (Palo Alto, California);  Pedro Ruiz (Menlo Park, California);  Hideki Garren (Palo Alto, California)
ABSTRACT A pro-inflammatory T cell response is specifically suppressed by the injection into a recipient of DNA encoding an autoantigen associated with autoimmune disease. The recipient may be further treating by co-vaccination with a DNA encoding a Th2 cytokine, particularly encoding IL4. In response to the vaccination, the proliferation of autoantigen-reactive T cells and the secretion of Th1 cytokines, including IL-2, IFN-γ and IL-15, are reduced.
FILED Monday, April 05, 2010
APPL NO 12/754555
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748405 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Hua Yu (Glendora, California);  Marcin Kortylewski (Monrovia, California);  Richard Jove (Glendora, California);  Piotr Marek Swiderski (San Dimas, California);  John J. Rossi (Alta Loma, California)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Hua Yu (Glendora, California);  Marcin Kortylewski (Monrovia, California);  Richard Jove (Glendora, California);  Piotr Marek Swiderski (San Dimas, California);  John J. Rossi (Alta Loma, California)
ABSTRACT The present invention relates to methods and compositions for the treatment of diseases, including cancer, infectious diseases and autoimmune diseases. The present invention also relates to methods and compositions for improving immune function. More particularly, the present invention relates to multifunctional molecules that are capable of being delivered to cells of interest for the treatment of diseases and for the improvement in immune function.
FILED Friday, September 09, 2011
APPL NO 13/229146
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.A00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748445 Chung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) W. Joon Chung (Birmingham, Alabama);  Harald Sontheimer (Birmingham, Alabama)
ASSIGNEE(S) The UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S) W. Joon Chung (Birmingham, Alabama);  Harald Sontheimer (Birmingham, Alabama)
ABSTRACT The present disclosure provides for method of treatment and/or prevention of disease states that require cystine for maintenance or progression of the disease state. In addition, methods for screening and identifying novel therapeutic agents useful in the treatment of such disease states are described. In one embodiment, the disease state is a cancer, such as, but not limited to, glioma. In this embodiment, methods for the treatment and prevention of glioma by inhibiting cystine uptake or decreasing intracellular cystine concentrations are provided. The present disclosure teaches that glioma cells are dependent on system Xc for cystine uptake. Pharmacological inhibition of system Xc causes a rapid depletion of intracellular glutathione, resulting in decreased cell growth. In contrast, non-malignant astrocytes and cortical neurons remain viable in the presence of Xc inhibitors and continue to take up cystine via alternate amino acid transporters.
FILED Thursday, October 27, 2005
APPL NO 11/791588
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/275
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748451 Kozikowski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of The University of Illinois (Urbana, Illinois)
INVENTOR(S) Alan Kozikowski (Chicago, Illinois);  Kyle Vincent Butler (Stanford, California);  Jay Hans Kalin (Chicago, Illinois)
ABSTRACT Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, traumatic brain injury, stroke, malaria, an autoimmune disease, autism, and inflammation, also are disclosed.
FILED Monday, April 22, 2013
APPL NO 13/867438
ART UNIT 1676 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/292
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748464 Verdin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Eric M. Verdin (San Francisco, California);  Melanie Ott (San Francisco, California);  Hye-Sook Kwon (San Mateo, California);  Hyungwook Lim (San Francisco, California)
ASSIGNEE(S) The J. David Gladstone Institutes (San Francisco, California)
INVENTOR(S) Eric M. Verdin (San Francisco, California);  Melanie Ott (San Francisco, California);  Hye-Sook Kwon (San Mateo, California);  Hyungwook Lim (San Francisco, California)
ABSTRACT The present disclosure provides a method of increasing an immune response in an individual, the method involving administering to an individual in need thereof an inhibitor of SIRT1. The present disclosure provides a method of reducing an immune response, e.g., to treat chronic immune hyperactivity, the method generally involving administering to an individual in need thereof an activator of SIRT1. The present disclosure provides a method of modulating activation and differentiation of CD4+ T cells.
FILED Friday, July 16, 2010
APPL NO 12/838247
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/366
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748469 Mautino et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Mario R. Mautino (Ankeny, Iowa);  Sanjeev Kumar (Ames, Iowa);  Firoz Jaipuri (Ames, Iowa);  Jesse Waldo (Ames, Iowa);  Tanay Kesharwani (Lake Katrine, New York);  Nicholas N. Vahanian (Polk City, Iowa);  Charles J. Link (Clive, Iowa)
ASSIGNEE(S) NewLink Genetics Corporation (Ames, Iowa);  Lankeanau Institute for Medical Research (Wynnewood, Pennsylvania)
INVENTOR(S) Mario R. Mautino (Ankeny, Iowa);  Sanjeev Kumar (Ames, Iowa);  Firoz Jaipuri (Ames, Iowa);  Jesse Waldo (Ames, Iowa);  Tanay Kesharwani (Lake Katrine, New York);  Nicholas N. Vahanian (Polk City, Iowa);  Charles J. Link (Clive, Iowa)
ABSTRACT Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R1, R4, and R5 are defined herein. Such compounds and compositions are useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine -2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease.
FILED Friday, April 24, 2009
APPL NO 12/988391
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/399
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748470 Lengyel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Ernst Lengyel (Chicago, Illinois);  Kristin Nieman (Westchester, Illinois);  Hilary Kenny (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Ernst Lengyel (Chicago, Illinois);  Kristin Nieman (Westchester, Illinois);  Hilary Kenny (Chicago, Illinois)
ABSTRACT The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins.
FILED Friday, March 16, 2012
APPL NO 13/422712
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/406
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748473 McKnight et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of the Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Steven L. McKnight (Dallas, Texas);  Andrew A. Pieper (Iowa City, Iowa);  Joseph M. Ready (Carrollton, Texas);  Jef K. De Brabander (Flower Mound, Texas)
ABSTRACT This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death.
FILED Monday, January 14, 2013
APPL NO 13/740876
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/403 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748480 Smrcka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Rochester (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Alan V. Smrcka (Rochester, New York);  Jose Font (Fairport, New York);  Tabetha Bonacci (Kimball, Minnesota)
ABSTRACT The present invention relates to methods for identifying agents which bind to specific amino acid residues of the protein interaction site of G protein β protein subunit. Compounds identified in accordance with the assay of the invention and methods for using the compound for modulating at least one activity of a G protein are also provided.
FILED Friday, September 28, 2012
APPL NO 13/630995
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/454
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748567 Narasimhaswamy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Manjunath Narasimhaswamy (El Paso, Texas);  Premlata Shankar (El Paso, Texas);  Priti Kumar (Hamden, Connecticut)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Manjunath Narasimhaswamy (El Paso, Texas);  Premlata Shankar (El Paso, Texas);  Priti Kumar (Hamden, Connecticut)
ABSTRACT The present invention provides compositions and methods useful for delivering agents to target cells or tissues, for example nerve cells and other cells in the central nervous system. The compositions and methods are useful for delivering agents across the blood-brain barrier. The present invention also provides methods of using the compositions provided by the present invention to deliver agents, for example therapeutic agents for the treatment of neurologically related disorders.
FILED Tuesday, May 22, 2007
APPL NO 12/301847
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748568 Goldfarb et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Mitchell Goldfarb (River Edge, New Jersey);  Dover Katarzyna (Riverdale, New York)
ASSIGNEE(S) Research Foundation of The City University of New York (New York, New York)
INVENTOR(S) Mitchell Goldfarb (River Edge, New Jersey);  Dover Katarzyna (Riverdale, New York)
ABSTRACT Isolated peptides are provided that are effective in inducing long-term inactivation of voltage-gated sodium channels (VGSCs) in mammalian cells. Such peptides are useful in reducing the action potentials of these excitable cells, for example, neurons, myocytes, and tonic muscle cells, in mammals in need thereof.
FILED Thursday, May 06, 2010
APPL NO 13/319016
ART UNIT 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/47 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748569 Stupp et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Samuel I. Stupp (Chicago, Illinois);  Joshua E. Goldberger (Columbus, Ohio);  Eric J. Berns (Chicago, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Samuel I. Stupp (Chicago, Illinois);  Joshua E. Goldberger (Columbus, Ohio);  Eric J. Berns (Chicago, Illinois)
ABSTRACT The present invention is directed to peptide amphiphile compounds, compositions and methods of use, wherein nanofiber bundling or epitope aggregation is inhibited. In certain embodiments, the peptide amphiphiles of the present invention have increased solubility and reduced nanofiber bundling. The molecules may be used in pharmaceutical applications, for example for in vivo administration to human patients, by increasing biological activity of the compositions toward neurite outgrowth and nerve regeneration.
FILED Monday, April 09, 2012
APPL NO 13/442210
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5169 (20130101)
A61K 38/00 (20130101) Original (OR) Class

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 2/00 (20130101)
C07K 2319/735 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/795 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748572 Nitto et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Takeaki Nitto (Saga, Japan);  Kimberly D. Dyer (Reston, Virginia);  Meggan Czapiga (Bethesda, Maryland);  Helene F. Rosenberg (Bethesda, Maryland);  Steven J. Siegel (Rockville, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Takeaki Nitto (Saga, Japan);  Kimberly D. Dyer (Reston, Virginia);  Meggan Czapiga (Bethesda, Maryland);  Helene F. Rosenberg (Bethesda, Maryland);  Steven J. Siegel (Rockville, Maryland)
ABSTRACT The present invention features isolated polypeptides that have bactericidal and angiogenic activities. The invention features isolated polypeptides comprising amino acid sequences of RNase A ribonucleases, fragments and variants thereof, pharmaceutical compositions, and methods for treatment of a subject.
FILED Friday, August 24, 2007
APPL NO 12/438700
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748591 Weaver et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Scott C. Weaver (Galveston, Texas);  Ilya Frolov (Galveston, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Scott C. Weaver (Galveston, Texas);  Ilya Frolov (Galveston, Texas)
ABSTRACT The present invention discloses a chimeric alphavirus comprising a Sindbis virus cDNA fragment, an Eastern equine encephalitis virus cDNA fragment, a Western equine encephalitis virus cDNA fragment or a combination thereof. The present also discloses the use of this chimeric alphavirus as vaccines and in serological and diagnostic assays.
FILED Thursday, April 17, 2008
APPL NO 12/148172
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.720
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748601 Taunton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Jack Taunton (San Francisco, California);  Michael Cohen (San Francisco, California);  Kevan Shokat (San Francisco, California);  Chao Zhang (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jack Taunton (San Francisco, California);  Michael Cohen (San Francisco, California);  Kevan Shokat (San Francisco, California);  Chao Zhang (San Francisco, California)
ABSTRACT Inhibition of protein kinases having one or more cysteine residues within the ATP binding site is effected by contacting the kinase, per se or in a cell or subject, with an inhibitory-effective amount of a compound having a heterocyclic core structure comprised of two or more fused rings containing at least one nitrogen ring atom, and an electrophilic substituent that is capable of reacting with a cysteine residue within the ATP binding site of a kinase. Preferred compounds include certain pyrrolopyrimidines and oxindoles having such an electrophilic substituent and optionally an aromatic or heteroaromatic substituent that is capable of interacting with a threonine or smaller residue located in the gatekeeper position of the kinase. Kinases lacking such cysteine residues may be engineered or modified so that they are capable of being inhibited by such compounds by replacing a valine or other amino acid residue within the ATP binding site by a cysteine residue.
FILED Tuesday, September 26, 2006
APPL NO 12/088059
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748608 Newman et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Amy Hauck Newman (Phoenix, Maryland);  Peter Grundt (Duluth, Minnesota);  George C. Cyriac (Severna Park, Maryland);  Robert Luedtke (Fort Worth, Texas);  Jianjing Cao (Ellicott City, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia);  The University of North Texas Health Science Center at Fort Worth (Fort Worth, Texas)
INVENTOR(S) Amy Hauck Newman (Phoenix, Maryland);  Peter Grundt (Duluth, Minnesota);  George C. Cyriac (Severna Park, Maryland);  Robert Luedtke (Fort Worth, Texas);  Jianjing Cao (Ellicott City, Maryland)
ABSTRACT Dopamine D3 receptor antagonists and partial agonists are known to modulate the reinforcing and drug-seeking effects induced by cocaine and other abused substances. By introducing functionality into the butylamide linking chain of the 4-phenylpiperazine class of ligands, improved D3 receptor affinity and selectivity, as well as water solubility, is achieved. A series of linking-chain derivatives are disclosed wherein functionality such as OH or OAc groups have been introduced into the linking chain. In general, these modifications are well tolerated at D3 receptors and achieve high selectivity over D2 and D4 receptors.
FILED Friday, June 15, 2007
APPL NO 12/664668
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Organic compounds
544/360
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748618 Bushweller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) John H. Bushweller (Charlottesville, Virginia);  Jolanta Grembecka (Ann Arbor, Michigan);  Anuradha Illendula (Charlottesville, Virginia);  Lauren Dixon (Ann Arbor, Michigan)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) John H. Bushweller (Charlottesville, Virginia);  Jolanta Grembecka (Ann Arbor, Michigan);  Anuradha Illendula (Charlottesville, Virginia);  Lauren Dixon (Ann Arbor, Michigan)
ABSTRACT This invention describes the development of targeted small molecule inhibitors of the inv(16) fusion, the causative agent in ˜12% of acute myeloid leukemia (AML). The inv(16) fusion results in expression of the CBFβ-SMMHC fusion protein in the blood cells of afflicted patients. The present invention provides compounds which inhibit the function of both CBFβ and the CBFβ-SMMHC fusion. These compounds block the growth of an inv(16) leukemia cell line as well as increase its apoptosis, while showing minimal effects against non inv(16) cell lines. As a mechanism to develop inhibitors with selectivity for the CBFβ-SMMHC fusion protein, the present invention further provides dimeric derivatives of these compounds which show both increased potency as well selectivity for CBFβ-SMMHC. These compounds show potent inhibition of an inv(16) leukemia cell line with minimal effects on non inv(16) cell lines. Analysis of the pharmacokinetics of the developed compounds has made it possible to improve the lifetime of the compound in the plasma of mice to a level commensurate with long-term treatment.
FILED Thursday, May 13, 2010
APPL NO 13/320123
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/256
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748623 Maeda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Dean Y. Maeda (Seattle, Washington);  John A. Zebala (Sammamish, Washington)
ASSIGNEE(S) Syntrix Biosystems, Inc. (Auburn, Washington)
INVENTOR(S) Dean Y. Maeda (Seattle, Washington);  John A. Zebala (Sammamish, Washington)
ABSTRACT There is disclosed pyridine-and pyrimidinecarboxamide compounds useful as pharmaceutical agents, synthesis processes, and pharmaceutical compositions which include pyridine-and pyrimidinecarboxamides compounds. More specifically, there is disclosed a genus of CXCR2 inhibitor compounds that are useful for treating a variety of inflammatory and neoplastic disorders.
FILED Wednesday, February 17, 2010
APPL NO 12/707647
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/297
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748632 Cosford et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Nicholas D. P. Cosford (La Jolla, California);  Dhanya Raveendra Panickar (La Jolla, California);  Shyama Sidique (La Jolla, California);  Svetlana Semenova (La Jolla, California);  Athinia Markou (La Jolla, California)
ASSIGNEE(S) Sanford-Burnham Medical Research Institute (La Jolla, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Nicholas D. P. Cosford (La Jolla, California);  Dhanya Raveendra Panickar (La Jolla, California);  Shyama Sidique (La Jolla, California);  Svetlana Semenova (La Jolla, California);  Athinia Markou (La Jolla, California)
ABSTRACT The disclosure provides compounds and compositions, and methods of using these compounds and compositions, as positive allosteric modulators of the metabotropic glutamate subtype 2 (mGlu2) receptor, and for treating CNS disorders associated with the mGlu2 receptor including schizophrenia, anxiety, addiction, e.g. cocaine addiction, nicotine addiction, and the like.
FILED Friday, March 18, 2011
APPL NO 13/051798
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4035 (20130101)

Heterocyclic Compounds
C07D 209/46 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748933 Bawendi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Moungi G. Bawendi (Cambridge, Massachusetts);  Sang-wook Kim (Brookline, Massachusetts);  John P. Zimmer (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Moungi G. Bawendi (Cambridge, Massachusetts);  Sang-wook Kim (Brookline, Massachusetts);  John P. Zimmer (Cambridge, Massachusetts)
ABSTRACT Semiconductor nanocrystals including III-V semiconductors can include a core including III-V alloy. The nanocrystal can include an overcoating including a II-VI semiconductor.
FILED Monday, March 12, 2012
APPL NO 13/417894
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/103
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750586 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Ruikang Wang (Portland, Oregon);  Lin An (Portland, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) Ruikang Wang (Portland, Oregon);  Lin An (Portland, Oregon)
ABSTRACT Embodiments provide methods and systems for quantitative imaging of blood perfusion in living tissue. A method provides for obtaining an optical microangiography (OMAG) image of a sample, wherein the image has an OMAG background sample; digitally reconstructing a homogeneous ideal static background tissue; replacing the OMAG background sample with the digitally reconstructed homogeneous ideal static background tissue; correlating two or more neighboring A-lines with the digitally reconstructed homogeneous ideal static background tissue; and measuring a phase difference between the two or more neighboring A-lines to quantify blood perfusion in the sample. Methods using digital reconstruction to reduce random phase noise in phase-resolved Doppler OCT are also provided.
FILED Tuesday, May 04, 2010
APPL NO 13/318737
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/130
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750642 Corum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Curtis A. Corum (Shoreview, Minnesota);  Djaudat S. Idiyatullin (New Brighton, Minnesota);  Steen Moeller (Golden Valley, Minnesota);  Michael G. Garwood (Medina, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Curtis A. Corum (Shoreview, Minnesota);  Djaudat S. Idiyatullin (New Brighton, Minnesota);  Steen Moeller (Golden Valley, Minnesota);  Michael G. Garwood (Medina, Minnesota)
ABSTRACT This document discloses, among other things, a method for removing a bullseye artifact from a radial image generated using magnetic resonance and using a swept frequency pulse.
FILED Friday, July 06, 2012
APPL NO 13/543706
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/275
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750652 Butte et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Manish J. Butte (Stanford, California);  John J. LeBlanc (North Andover, Massachusetts)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California);  The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Manish J. Butte (Stanford, California);  John J. LeBlanc (North Andover, Massachusetts)
ABSTRACT A microfluidic detection device is provided that includes a planar waveguide, or an ion-exchange planar waveguide, a microfluidic channel disposed on the planar waveguide, a light source, such as a laser, LED or incandescent light, directed through the planar waveguide, a labeled cell disposed in the microfluidic channel, where the labeled cell lies in an evanescent field extending from the planar waveguide, and a light detector disposed to receive light from the light source through the planar waveguide. The evanescent field interacts with the labeled cell, where the light through the planar waveguide is altered according to a presence of the labeled cell in the microfluidic channel.
FILED Wednesday, October 12, 2011
APPL NO 13/317180
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/12
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08752006 Tolle
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Gilman Tolle (San Francisco, California)
ASSIGNEE(S) Cisco Technology, Inc. (San Jose, California)
INVENTOR(S) Gilman Tolle (San Francisco, California)
ABSTRACT A system and method accepts source code for one or more procedures and, for those procedures flagged as being remotely callable, generates communication code and a description that allows the code to be remotely callable via a server using a variety of formats, such as conventional web services formats.
FILED Monday, July 02, 2007
APPL NO 11/824956
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/106
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08752071 Thomas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Philip J. Thomas (Lutterworth, United Kingdom);  Martin J. Gale (Eastleigh, United Kingdom)
ASSIGNEE(S) International Business Machines Corporation (New York, New York);  The United States of America as represented by National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS) (Washington, District of Columbia)
INVENTOR(S) Philip J. Thomas (Lutterworth, United Kingdom);  Martin J. Gale (Eastleigh, United Kingdom)
ABSTRACT A solution for managing messaging is provided in which an event related to a publisher is identified. In response to the event, a transaction is initiated for processing the event, the event is processed within the transaction, and the transaction is committed after the event is processed. During processing, data corresponding to the event is provided for use by a set of subscribers to the event, and data related to the set of subscribers is identified. In an embodiment, a message broker in a publication and subscribe messaging environment implements the solution in order to be capable of providing the data related to the set of subscribers to the publisher. Use of the transaction ensures that the data related to the set of subscribers accurately represents the set of subscribers at the time that the data corresponding to the event was provided.
FILED Friday, December 19, 2008
APPL NO 12/339749
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers and digital processing systems: Interprogram communication or interprocess communication
719/318
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 08745853 Grbic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Anthony Grbic (Ann Arbor, Michigan);  Carl Pfeiffer (Milford, Michigan);  Xin Xu (West Windsor, New Jersey);  Stephen Forrest (Ann Arbor, Michigan)
ASSIGNEE(S) Universal Display Corporation (Ewing, New Jersey);  The Regents of the University of Michigan, University of Michigan Office of Technology Transfer (Ann Arbor, Michigan)
INVENTOR(S) Anthony Grbic (Ann Arbor, Michigan);  Carl Pfeiffer (Milford, Michigan);  Xin Xu (West Windsor, New Jersey);  Stephen Forrest (Ann Arbor, Michigan)
ABSTRACT Disclosed herein is a method of fabricating an antenna in which a flexible stamp is formed from a first wafer, the first wafer transferring a pattern to the flexible stamp, in which an antenna substrate is shaped into a three-dimensional contour with a second mold, in which the flexible stamp is positioned in the second mold to deform the flexible stamp into the three-dimensional contour, and in which a metallic layer on the flexible stamp is cold welded to create a set of antenna traces on the antenna substrate in accordance with the pattern. The antenna traces may then be electroplated.
FILED Tuesday, July 05, 2011
APPL NO 13/176053
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08746120 Nolting et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Eugene Ellis Nolting (Columbia, Maryland);  William Bryan Maier, II (Marina, California);  Gene Morris (Seaside, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Eugene Ellis Nolting (Columbia, Maryland);  William Bryan Maier, II (Marina, California);  Gene Morris (Seaside, California)
ABSTRACT A device and method which combine electromagnetic acceleration with acceleration by high-pressure gases derived from chemical energy to achieve high slug speeds. In one embodiment the device includes a cylindrical metal tube having an outer diameter and an inner diameter and a central channel; at least one conductive coil surrounding the metal tube; a metal slug disposed within the central channel; a conducting central electrode, having a centrally formed cavity; a conducting rod having at least one cavity including a propellant, wherein a first portion of the conducting rod is attached to the metal slug at a connection point, a second portion of the conducting rod extends between the metal slug and the central electrode, and a third portion of the conducting rod extends within the cavity of the central electrode such that a space is formed between the end of the third portion and the back of the cavity within the central electrode; and an insulator disposed within the central channel and surrounding the conducting central electrode and the second portion of the conducting rod except at the connection point. When a current is applied to the metal tube, the central electrode, and the at least one conductive coil causes the conducting rod to break with resultant generation of a plasma which ignites the propellant such that the energy from the propellant and electromagnetic forces accelerate the slug to speeds greater than are achievable by the propellant alone.
FILED Friday, October 19, 2012
APPL NO 13/656464
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/8
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08746122 Roland et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Charles M. Roland (Waldorf, Maryland);  Daniel M. Fragiadakis (Alexandria, Virginia);  Raymond M. Gamache (Indian Head, Maryland)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Charles M. Roland (Waldorf, Maryland);  Daniel M. Fragiadakis (Alexandria, Virginia);  Raymond M. Gamache (Indian Head, Maryland)
ABSTRACT An armor system with a composite laminate having at least four alternating layers (two bi-layers) of a first material and a second material, the first material having a lower acoustic impedance than the second material. The first material is a viscoelastic polymer with a glass transition temperature less than the expected operational temperature range, and the second material can be a hard material such as steel, aluminum, or ceramic. The laminate can include many alternating layers of elastomer and hard material, and can be adhered or affixed to a thicker armor substrate. Additional protective elements such as corrugated metal-ceramic panels and armored glass cylinders can be added to improve resistance to armor piercing rounds, explosively formed penetrators, or other threats.
FILED Thursday, March 14, 2013
APPL NO 13/829977
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/36.20
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08746124 Cannon
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Joseph P. Cannon (Lenox, Michigan)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Joseph P. Cannon (Lenox, Michigan)
ABSTRACT Reactive armor that includes a casing having a plurality of walls, a back, and a cavity formed therebetween; a cover that closes the cavity and forms a strike face; a filler placed within the cavity, the filler comprising a disruptive material; and an explosive. To defeat projectile or projectile related threats, the reactive armor substantially, but not necessarily wholly, implements laterally oriented force mechanisms, erosion mechanisms, and bulking mechanisms, e.g., explosive forces, with respect to the strike face.
FILED Thursday, July 26, 2012
APPL NO 13/559405
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/36.170
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08746404 Allam
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Mahdy A. Allam (Glastonbury, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Mahdy A. Allam (Glastonbury, Connecticut)
ABSTRACT Gas turbine engines systems and methods involving oil flow management are provided. In this regard, a oil pressure analysis system for a gas turbine engine is operative to: receive information corresponding to measured oil pressure and rotational speed during a start up of the engine; correlate the information into data sets, each of the data sets containing a measured oil pressure and a corresponding rotational speed; and determine whether the oil flow valve is functioning properly based on the information contained in the data sets.
FILED Wednesday, July 30, 2008
APPL NO 12/182265
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Lubrication
184/6.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08746741 Gonzalez
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Rene′ G. Gonzalez (Southfield, Michigan)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Rene′ G. Gonzalez (Southfield, Michigan)
ABSTRACT A mechanism protecting vehicle occupants from floor oscillation during under-vehicle explosions comprises vehicle cab sidewalls, a cab floor, cab mounts having elastomeric bodies between the cab and vehicle frame members, a shield below the cab floor, first elastomeric isolators between the shield and frame, and second elastomeric isolators between the shield and sidewalls. The second isolators collapse by an amount equal to the combined collapse of the first isolators and cab mounts. Explosive loads to the shield follow paths to different floor zones, decreasing floor oscillation. A vehicle payload area is mounted to the frame separately from the cab. The payload area and cab move independently on the frame. The payload area mounts are stiffer and smaller than the cab mounts, so explosions under the vehicle tend to accelerate the payload area before the cab.
FILED Wednesday, November 14, 2012
APPL NO 13/677202
ART UNIT 3616 — Optics
CURRENT CPC
Land vehicles
280/784
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747041 Gonzalez
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Rene′ G. Gonzalez (Southfield, Michigan)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Rene′ G. Gonzalez (Southfield, Michigan)
ABSTRACT An improved nut-and-bolt assembly reduces tensile stress concentration on the bolt. The assembly has a specially designed nut with a tapered region extending from the nut crown and threaded with the first several bolt threads. The cross sectional area of the tapered region decreases linearly as a function of distance from the crown whereby the tapered region has a convex profile. Each of the bolt threads engaging the tapered region take up an approximately equal amount of longitudinal stress on the bolt.
FILED Tuesday, March 26, 2013
APPL NO 13/850608
ART UNIT 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Expanded, threaded, driven, headed, tool-deformed, or locked-threaded fastener
411/366.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747092 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Wei Zhang (Newtown, Pennsylvania);  Hua Tan (Princeton Junction, New Jersey);  Lin Hu (Livingston, New Jersey);  Stephen Y. Chou (Princeton, New Jersey)
ASSIGNEE(S) Nanonex Corporation (Monmouth Junction, New Jersey)
INVENTOR(S) Wei Zhang (Newtown, Pennsylvania);  Hua Tan (Princeton Junction, New Jersey);  Lin Hu (Livingston, New Jersey);  Stephen Y. Chou (Princeton, New Jersey)
ABSTRACT The invention disclosed apparatuses and methods to do nanoimprint lithography using a deformable mold. Generally, the apparatus has a chamber with a transparent section on its top wall, which is capable of vacuuming and pressurizing. The deformable mold fixed firmly onto a hollow mold holder around its full periphery is attached to top inner surface of the chamber and positioned underneath the transparent section. The central area of the mold is freely accessible from underneath through the opening of the mold holder. An enclosed volume referring to mold mini-chamber is formed between the mold/holder and top wall of the chamber. Inside chamber, a stage assembly is installed. A chuck to vacuumly hold a substrate is mounted on top of the stage assembly. At beginning of the imprinting, the substrate with a layer of resist is positioned underneath the mold at a predetermined gap between them. Then, the substrate is moved up to contact with the mold either under vacuum or under atmosphere. The substrate and mold may be pressed further by introducing higher pressure inside the chamber. After consolidating the resist, the substrate is separated from the mold by either direct pull-down enabled by stage movement or deforming the mold enabled by differential pressure between the mold mini-chamber and the bulk volume of the chamber, or mixing of both.
FILED Friday, January 21, 2011
APPL NO 13/011844
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic article or earthenware shaping or treating: Apparatus
425/150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747122 Banitt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Terry F. Banitt (Altura, Minnesota);  John L. Colbert (Byron, Minnesota);  Jason R. Eagle (Kasson, Minnesota);  Roger S. Krabbenhoft (Rochester, Minnesota)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Terry F. Banitt (Altura, Minnesota);  John L. Colbert (Byron, Minnesota);  Jason R. Eagle (Kasson, Minnesota);  Roger S. Krabbenhoft (Rochester, Minnesota)
ABSTRACT A method and apparatus are provided for implementing electrical connection of two large circuit cards through multiple discrete land grid array (LGA) sites. Each of the circuit cards includes a plurality of LGA sites. A first circuit card includes a plurality of LGA interposers locally aligned at the respective LGA sites of the first circuit card. A board-to-board connection hardware assembly connecting a second circuit card to the first circuit card includes a elongated carrier defining a cavity receiving a plurality of load springs coupled to an associated bearing block for loading and maintaining flatness of the LGA sites.
FILED Wednesday, June 23, 2010
APPL NO 12/821312
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electrical connectors
439/66
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747126 Corbett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Blaise L. Corbett (King George, Virginia);  David J. Griffiths (King George, Virginia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Blaise L. Corbett (King George, Virginia);  David J. Griffiths (King George, Virginia)
ABSTRACT An adapter is provided for electrically connecting an interior surface of a conduit and an external surface of a cable. The adapter includes a flat strip extending longitudinally from first to second ends with first and second transverse edges and composed of an electrically conductive and mechanically flexible material. The strip includes a longitudinal ribbon that forms a ring for wrapping around the cable by curling the first and second ends together in a direction transverse to the sheet, and a plurality of first and second incisions from the transverse edges towards the ribbon, the incisions being disposed at respective intervals that correspond to a longitudinally regular pattern. The first incisions form tapering tabs for bending in the direction transverse to the sheet to produce petals that extend radially inward from the ring to engage the cable. The second incisions form peripheral tabs for bending in an opposite direction transverse to the sheet to produce flanges that extend radially outward from the ring to engage the conduit.
FILED Thursday, October 10, 2013
APPL NO 14/051385
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Electrical connectors
439/98
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747631 Wei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Ronghua Wei (San Antonio, Texas);  Edward Langa (San Antonio, Texas);  Sabrina L. Lee (Schenectaday, New York)
ASSIGNEE(S) Southwest Research Institute (San Antonio, Texas)
INVENTOR(S) Ronghua Wei (San Antonio, Texas);  Edward Langa (San Antonio, Texas);  Sabrina L. Lee (Schenectaday, New York)
ABSTRACT The present disclosure relates to an apparatus and method utilizing double glow discharge for sputter cleaning of a selected surface. The surface may include the inner surface of a hollow substrate such as a tube which inner surface may then be coated via magnetron sputter deposition.
FILED Monday, March 15, 2010
APPL NO 12/723816
ART UNIT 1754 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemistry: Electrical and wave energy
24/192.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747656 Tonkovich et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Anna Lee Tonkovich (Dublin, Ohio);  Ravi Arora (New Albany, Ohio);  John Brophy (Bath, United Kingdom);  Francis P. Daly (Delaware, Ohio);  Soumitra Deshmukh (Dublin, Ohio);  Maddalena Fanelli (Columbus, Ohio);  Kai Tod Paul Jarosch (Bexley, Ohio);  Timothy J. LaPlante (Powell, Ohio);  Richard Q. Long (New Albany, Ohio);  Terry Mazanec (Solon, Ohio);  Daniel Francis Ryan (Brewster, Massachusetts);  Laura J. Silva (Dublin, Ohio);  Wayne W. Simmons (Dublin, Ohio);  Bruce Stangeland (Berkeley, California);  Yong Wang (Richland, Washington);  Thomas Yuschak (Lewis Center, Ohio);  Steven T. Perry (Galloway, Ohio);  Jeffrey Dale Marco (South Charleston, Ohio);  Michael Alan Marchiando (London, Ohio);  Robert Dwayne Litt (Westerville, Ohio)
ASSIGNEE(S) Velocys, Inc. (Plain City, Ohio)
INVENTOR(S) Anna Lee Tonkovich (Dublin, Ohio);  Ravi Arora (New Albany, Ohio);  John Brophy (Bath, United Kingdom);  Francis P. Daly (Delaware, Ohio);  Soumitra Deshmukh (Dublin, Ohio);  Maddalena Fanelli (Columbus, Ohio);  Kai Tod Paul Jarosch (Bexley, Ohio);  Timothy J. LaPlante (Powell, Ohio);  Richard Q. Long (New Albany, Ohio);  Terry Mazanec (Solon, Ohio);  Daniel Francis Ryan (Brewster, Massachusetts);  Laura J. Silva (Dublin, Ohio);  Wayne W. Simmons (Dublin, Ohio);  Bruce Stangeland (Berkeley, California);  Yong Wang (Richland, Washington);  Thomas Yuschak (Lewis Center, Ohio);  Steven T. Perry (Galloway, Ohio);  Jeffrey Dale Marco (South Charleston, Ohio);  Michael Alan Marchiando (London, Ohio);  Robert Dwayne Litt (Westerville, Ohio)
ABSTRACT This invention relates to a process for conducting a hydrocracking or a hydrotreating process in a microchannel reactor. This invention also relates to a process and apparatus for flowing a vapor and liquid into a plurality of microchannels in a microchannel processing unit.
FILED Friday, October 09, 2009
APPL NO 12/576458
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Mineral oils: Processes and products
28/113
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747730 Riehl
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) John Riehl (Hebron, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) John Riehl (Hebron, Connecticut)
ABSTRACT A method of forming a woven fiber structure for a molding process to produce a ceramic matrix composite, includes depositing a tackifier composition having a carrier solvent, a resin material, and an inorganic filler onto at least a portion of a woven fiber structure; drying the tackifier composition on woven fiber structure to remove at least a portion of the carrier solvent from the tackifier composition; and forming the dried woven fiber structure into a preform.
FILED Thursday, June 14, 2012
APPL NO 13/517880
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/589 (20130101)
C04B 35/806 (20130101)
C04B 35/6263 (20130101)
C04B 35/6286 (20130101)
C04B 35/62802 (20130101)
C04B 35/62847 (20130101)
C04B 35/62871 (20130101)
C04B 35/62886 (20130101)
C04B 68/63452 (20130101)
C04B 2235/524 (20130101)
C04B 2235/616 (20130101)
C04B 2235/5244 (20130101)
C04B 2235/5252 (20130101)
C04B 2235/5256 (20130101)

Compositions of Macromolecular Compounds
C08L 63/00 (20130101)
C08L 2205/02 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 163/00 (20130101) Original (OR) Class
C09J 163/00 (20130101)
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US 08747869 Irvine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Darrell J. Irvine (Arlington, Massachusetts);  Jaehyun Moon (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Darrell J. Irvine (Arlington, Massachusetts);  Jaehyun Moon (Cambridge, Massachusetts)
ABSTRACT The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents.
FILED Saturday, March 19, 2011
APPL NO 13/052067
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101) Original (OR) Class
A61K 9/1273 (20130101)
A61K 2039/55572 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747886 Amsden et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Jason J. Amsden (Eddington, Maine);  David L. Kaplan (Concord, Massachusetts);  Fiorenzo Omenetto (Wakefield, Massachusetts)
ASSIGNEE(S) Tufts University (Medford, Massachusetts)
INVENTOR(S) Jason J. Amsden (Eddington, Maine);  David L. Kaplan (Concord, Massachusetts);  Fiorenzo Omenetto (Wakefield, Massachusetts)
ABSTRACT The present invention provides for photonic nanoimprinted silk fibroin-based materials and methods for making same, comprising embossing silk fibroin-based films with photonic nanometer scale patterns. In addition, the invention provides for processes by which the silk fibroin-based films can be nanoimprinted at room temperature, by locally decreasing the glass transition temperature of the silk film. Such nanoimprinting process increases high throughput and improves potential for incorporation of silk-based photonics into biomedical and other optical devices.
FILED Friday, February 12, 2010
APPL NO 13/201380
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/443
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US 08748106 Singh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Bal Ram Singh (N. Dartmouth, Massachusetts);  Yu Zhou (New Bedford, Massachusetts)
ASSIGNEE(S) Bal Ram Singh (North Dartmouth, Massachusetts)
INVENTOR(S) Bal Ram Singh (N. Dartmouth, Massachusetts);  Yu Zhou (New Bedford, Massachusetts)
ABSTRACT This application is based, inter alia, on the discovery of a binding interaction between the Hn-33 hemagglutinin polypeptide of the type A Clostridium botulinum neurotoxin complex and synaptosomal proteins, including synaptotagmin II (Syt II). Methods of screening for compounds that modulate, e.g., increase or decrease, this interaction are provided. Also provided are compositions and methods for targeting compounds to neuronal and cancer cells by coupling the compounds to Hn-33 or biologically active Hn-33 variants.
FILED Tuesday, April 18, 2006
APPL NO 11/911889
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
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US 08748165 Vangbo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Mattias Vangbo (Fremont, California);  William D. Nielsen (San Jose, California);  Iuliu I. Blaga (Fremont, California);  Michael Van Nguyen (San Diego, California);  Steven B. Jovanovich (Livermore, California)
ASSIGNEE(S) IntegenX Inc. (Pleasanton, California)
INVENTOR(S) Mattias Vangbo (Fremont, California);  William D. Nielsen (San Jose, California);  Iuliu I. Blaga (Fremont, California);  Michael Van Nguyen (San Diego, California);  Steven B. Jovanovich (Livermore, California)
ABSTRACT This invention provides a method for generating short tandem repeat (STR) profiles on each of a plurality of samples comprising, for each sample: a) isolating DNA from the sample; b) amplifying STR markers in the isolated DNA and c) analyzing the amplification product by electrophoresis.
FILED Tuesday, August 21, 2012
APPL NO 13/590965
ART UNIT 1775 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/287.200
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US 08748180 Shuler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Construction Engineering Research Laboratory (CERL)
U.S. Army Corps of Engineers (USACE)
Engineer Research and Development Center (ERDC)
Construction Engineering Research Laboratory (CERL)
APPLICANT(S) Michael L. Shuler (Ithaca, New York);  Jong Hwan Sung (Seoul, South Korea)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Michael L. Shuler (Ithaca, New York);  Jong Hwan Sung (Seoul, South Korea)
ABSTRACT A microfluidic device for culturing cells, termed a microscale cell culture analog (μCCA), is provided. The microfluidic device allows multiple cell or tissue types to be cultured in a physiologically relevant environment, facilitates high-throughput operation and can be used for drug discovery. The microfluidic device uses gravity-induced fluidic flow, eliminating the need for a pump and preventing formation of air bubbles. Reciprocating motion between a pair of connected reservoirs is used to effect the gravity-induced flow in microfluidic channels. Bacterial contamination is reduced and high throughput enabled by eliminating a pump. The microfluidic device integrates a pharmacokinetic-pharmacodynamic (PK-PD) model to enable PK-PD analyses on-chip. This combined in vitro/in silico system enables prediction of drug toxicity in a more realistic manner than conventional in vitro systems.
FILED Thursday, July 29, 2010
APPL NO 13/387585
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/382
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US 08748181 Kuo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Po-Ling Kuo (Cambridge, Massachusetts);  Adam W. Feinberg (Cambridge, Massachusetts);  Kevin Kit Parker (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Po-Ling Kuo (Cambridge, Massachusetts);  Adam W. Feinberg (Cambridge, Massachusetts);  Kevin Kit Parker (Cambridge, Massachusetts)
ABSTRACT The present invention provides methods of generating and devices of patterned soft substrates, on which cells may be seeded, as well as methods of using these substrates. Devices containing these patterned soft substrates are also provided.
FILED Friday, May 22, 2009
APPL NO 12/994187
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/395
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US 08748331 Talley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Jeffrey W. Talley (South Bend, Indiana);  Steven Larson (Vicksburg, Mississippi);  Lawrence G. Wolfe (Saint Joseph, Michigan);  Brian D. Fisher (South Bend, Indiana)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Jeffrey W. Talley (South Bend, Indiana);  Steven Larson (Vicksburg, Mississippi);  Lawrence G. Wolfe (Saint Joseph, Michigan);  Brian D. Fisher (South Bend, Indiana)
ABSTRACT A method of manufacturing a remediation material uses a biogenic material as a substrate and involves preparing the surface of the substrate to enable a chemical reaction, and performing template-driven surface derivatization on the substrate to provide a net positive charge on the substrate. The remediation material may be placed into contact with surface water, ground water, soil, or sediment by at least one of a permeable reactive barrier, direct well injection, or direct introduction of the remediation material into soil or sediment, to remove contaminants from the surface water, ground water, soil, or sediment.
FILED Wednesday, October 01, 2008
APPL NO 12/243708
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/11
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US 08748407 Niu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The Research Foundation for the State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Li Niu (Loudonville, New York);  Zhen Huang (Latham, New York)
ABSTRACT The present invention relates to novel nucleic acid ligands or aptamers that demonstrate potent and selective inhibition of the open-channel conformation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors.
FILED Monday, February 25, 2013
APPL NO 13/775947
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748565 Brandt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Curtis R. Brandt (Stoughton, Wisconsin);  Hermann Bultmann (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Reseach Foundation (Madison, Wisconsin)
INVENTOR(S) Curtis R. Brandt (Stoughton, Wisconsin);  Hermann Bultmann (Madison, Wisconsin)
ABSTRACT This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and nonenveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections.
FILED Wednesday, April 02, 2008
APPL NO 12/061378
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
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US 08748566 Brandt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Curtis R. Brandt (Stoughton, Wisconsin);  Hermann Bultmann (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Curtis R. Brandt (Stoughton, Wisconsin);  Hermann Bultmann (Madison, Wisconsin)
ABSTRACT This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and nonenveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections.
FILED Friday, November 07, 2008
APPL NO 12/291325
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
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US 08748569 Stupp et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Samuel I. Stupp (Chicago, Illinois);  Joshua E. Goldberger (Columbus, Ohio);  Eric J. Berns (Chicago, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Samuel I. Stupp (Chicago, Illinois);  Joshua E. Goldberger (Columbus, Ohio);  Eric J. Berns (Chicago, Illinois)
ABSTRACT The present invention is directed to peptide amphiphile compounds, compositions and methods of use, wherein nanofiber bundling or epitope aggregation is inhibited. In certain embodiments, the peptide amphiphiles of the present invention have increased solubility and reduced nanofiber bundling. The molecules may be used in pharmaceutical applications, for example for in vivo administration to human patients, by increasing biological activity of the compositions toward neurite outgrowth and nerve regeneration.
FILED Monday, April 09, 2012
APPL NO 13/442210
ART UNIT 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5169 (20130101)
A61K 38/00 (20130101) Original (OR) Class

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 2/00 (20130101)
C07K 2319/735 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/795 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748639 Sleadd et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Bradley A. Sleadd (La Plata, Maryland);  John Fronabarger (Sun Lakes, Arizona)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Bradley A. Sleadd (La Plata, Maryland);  John Fronabarger (Sun Lakes, Arizona)
ABSTRACT The present disclosure sets forth the compound 3-azidopicric acid and a method of making the same. The method of producing 3-azidopicric acid is a two step reaction process of first reacting 3-aminopicric acid with sulfuric acid and sodium nitrite, and then reacting the result of the first step with phosphoric acid and sodium azide. Additionally described is a method of producing KDNP (4,6-dinitro-7-hydroxybenzofuroxan, potassium salt), by reacting 3-AzPA with potassium bicarbonate.
FILED Tuesday, April 26, 2011
APPL NO 13/094563
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
552/8
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US 08748919 Chua
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Christopher L. Chua (San Jose, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Christopher L. Chua (San Jose, California)
ABSTRACT A light emitting device includes a p-side, an n-side, and an active layer between the p-side and the n-side. The p-side includes a p-side contact, an electron blocking layer, a p-side separate confinement heterostructure (p-SCH), and a p-cladding/current spreading region disposed between the p-SCH and the p-side contact. The n-side includes an n-side contact, and an n-side separate confinement heterostructure (n-SCH). The active layer is configured to emit light in a wavelength range, wherein the p-side and the n-side have asymmetrical optical transmission properties with respect to the wavelength range emitted by the active layer.
FILED Thursday, April 28, 2011
APPL NO 13/096988
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/94
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US 08748950 Levy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Jeremy Levy (Pittsburgh, Pennsylvania);  Cheng Cen (Pittsburgh, Pennsylvania);  Patrick Irvin (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Jeremy Levy (Pittsburgh, Pennsylvania);  Cheng Cen (Pittsburgh, Pennsylvania);  Patrick Irvin (Pittsburgh, Pennsylvania)
ABSTRACT A reconfigurable device includes a first insulating layer, a second insulating layer, and a nanoscale quasi one- or zero-dimensional electron gas region disposed at an interface between the first and second insulating layers. The device is reconfigurable by applying an external electrical field to the electron gas, thereby changing the conductivity of the electron gas region. A method for forming and erasing nanoscale-conducting structures employs tools, such as the tip of a conducting atomic force microscope (AFM), to form local electric fields. The method allows both isolated and continuous conducting features to be formed with a length well below 5 nm.
FILED Wednesday, November 17, 2010
APPL NO 13/509538
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/288
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US 08749079 Dunn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Paul M. Dunn (West Kingston, Rhode Island);  Christopher J. Egan (South Kingston, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Paul M. Dunn (West Kingston, Rhode Island);  Christopher J. Egan (South Kingston, Rhode Island)
ABSTRACT A compact Wankel expander-alternator combination is provided. The combination includes a stationary outer housing that has embedded stator coils and a rotating inner housing having corresponding magnets disposed around the housing with the magnet/coil interaction generating power. Within the rotating housing, a three-sided rotor turns within a two lobed Wankel cavity, powered by working fluid acting on the rotor. The rotating housing and the rotor each circumscribe a stationary shaft. The shaft has an eccentric lobe about which the rotor turns on a bearing disposed between the rotor and the lobe. The rotating housing turns on bearings supported by the stationary shaft. The rotor and rotating housing are linked so that as the rotor turns in response to the working fluid force, the housing turns at a higher speed the speed ratio being preselected to achieve the desired output energy.
FILED Friday, April 01, 2011
APPL NO 13/078261
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Prime-mover dynamo plants
290/1.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749439 Rao et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Basrur Rama Rao (Lexington, Massachusetts);  Jeffrey Michael Elloian (Charlton, Massachusetts);  Eddie N. Rosario (Methuen, Massachusetts)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) Basrur Rama Rao (Lexington, Massachusetts);  Jeffrey Michael Elloian (Charlton, Massachusetts);  Eddie N. Rosario (Methuen, Massachusetts)
ABSTRACT Embodiments provide an integrated antenna system that enables dual-use operation (e.g., communications and navigation). In an embodiment, the integrated antenna system includes a sleeve monopole antenna system and stacked shorted annular ring (SAR) patch antenna system, which are compactly integrated to fit on a military handset or a smart phone. In an embodiment, the integrated antenna system enables communication in the 225-450 MHz Ultra-High Frequency (UHF) band and reception of various Global Navigation Satellite System (GNSS) bands.
FILED Monday, March 19, 2012
APPL NO 13/423982
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Communications: Radio wave antennas
343/725
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US 08749441 Fenn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Alan J. Fenn (Wayland, Massachusetts);  Peter T. Hurst (Cambridge, Massachusetts);  Jeffrey S. Herd (Rowley, Massachusetts);  Kenneth E. Kolodziej (Lexington, Massachusetts);  Leonard I. Parad (Acton, Massachusetts);  Hans Steyskal (Concord, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Alan J. Fenn (Wayland, Massachusetts);  Peter T. Hurst (Cambridge, Massachusetts);  Jeffrey S. Herd (Rowley, Massachusetts);  Kenneth E. Kolodziej (Lexington, Massachusetts);  Leonard I. Parad (Acton, Massachusetts);  Hans Steyskal (Concord, Massachusetts)
ABSTRACT Described is a simultaneous transmit and receive antenna system having a ring array of transmit antenna elements and a receive antenna element disposed on an axis that is perpendicular to and passing through the center of the ring array. Alternatively, the ring array includes receive elements and a transmit antenna element is disposed on the axis perpendicular to the ring array. Opposite antenna elements in the ring array differ in phase by 180° so that a radiation pattern null occurs at the antenna element at the center of the ring array. Also included are at least one ground plane and an electrically-conductive cylinder disposed on the perpendicular axis inside the ring array to provide a high degree of isolation between the transmit and receive antenna elements. The system may be configured for wireless communications, for example, according to WIFI IEEE standard 802.11 or WIMAX IEEE standard 802.16.
FILED Thursday, October 27, 2011
APPL NO 13/282700
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Communications: Radio wave antennas
343/793
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749545 Kelly et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) Ryan Edward George Kelly (Arlington, Virginia);  Felix Roach Hoots, Jr. (Clifton, Virginia)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Ryan Edward George Kelly (Arlington, Virginia);  Felix Roach Hoots, Jr. (Clifton, Virginia)
ABSTRACT Certain embodiments of the invention may include systems and methods visualizing space debris events. According to an example embodiment of the invention, a method is provided for visualizing positional probability of objects in space. The method includes receiving initial conditions of the objects, determining projected positions of the objects based, at least in part, on the initial conditions, determining a plurality of 2-dimensional (2D) boundaries around the projected positions; and assembling the plurality of 2D boundaries into a 3-dimensional (3D) representation of the positional probability of objects in space.
FILED Thursday, March 11, 2010
APPL NO 12/721912
ART UNIT 2614 — Electrical Circuits and Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/419
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US 08749640 Williams
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) Darin S. Williams (Tucson, Arizona)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Darin S. Williams (Tucson, Arizona)
ABSTRACT Blur-calibration of an imaging sensor includes moving a known target pattern across the field-of view (FOV) of the imaging sensor to present the target pattern across different frames at different pixel phases. The known target pattern comprises a plurality of point-like objects with fixed relative positions in which at least one point-like object has a different focus position. Frames of images of the moving target pattern as seen in the FOV of the imaging sensor are captured to sample point-like objects at different focus positions and generate a multi-focal image data output, which may be subsequently processed to generate data products at different focus positions from a high-resolution composite image generated from the captured frames.
FILED Tuesday, October 11, 2011
APPL NO 13/271155
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Television
348/188
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US 08749871 Montoya et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Juan C. Montoya (Belmont, Massachusetts);  Steven J. Spector (Lexington, Massachusetts);  Reuel Swint (Billerica, Massachusetts);  Caroline A. Ross (Arlington, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Juan C. Montoya (Belmont, Massachusetts);  Steven J. Spector (Lexington, Massachusetts);  Reuel Swint (Billerica, Massachusetts);  Caroline A. Ross (Arlington, Massachusetts)
ABSTRACT An optical structure for generating nonreciprocal loss is provided that includes a first substrate layer and a magneto-optical layer positioned on the first substrate layer. The magneto-optical layer achieves nonreciprocity with application of an external magnetic field so as to produce resonantly enhanced nonreciprocal loss.
FILED Wednesday, March 07, 2012
APPL NO 13/414289
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/093 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750077 Obara et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Michael J. Obara (North Kingstown, Rhode Island);  Timothy B. Straw (Narragansett, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael J. Obara (North Kingstown, Rhode Island);  Timothy B. Straw (Narragansett, Rhode Island)
ABSTRACT An acoustic ranging system and method of use is provided that measures the magnitude of the separation of a pair of towed acoustic line arrays at a discrete point along the length of each array. One array acts as the measurement source, while the other array acts as a frequency-shifted echo repeater. The source array incorporates one sonar transmitter and two sonar receivers. The system further includes a configurable frequency shifter that enables one measurement source to make measurements with multiple repeater arrays.
FILED Monday, June 25, 2012
APPL NO 13/531808
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/130
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US 08750354 Heruska et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) William M. Heruska (Sicklerville, New Jersey);  Michael Uscinowicz (Hainesport, New Jersey);  Gregory A. Arlow (Southampton, New Jersey);  Fred Tanjutco (Cherry Hill, New Jersey)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) William M. Heruska (Sicklerville, New Jersey);  Michael Uscinowicz (Hainesport, New Jersey);  Gregory A. Arlow (Southampton, New Jersey);  Fred Tanjutco (Cherry Hill, New Jersey)
ABSTRACT An open architecture design for a digital nearfield test system for nearfield testing of a phased array antenna allows the ability to use the components of an individual phased array antenna to be tested in conjunction with a nearfield scanner probe system allowing an efficient and cost-saving “radar testing the radar” scenario.
FILED Tuesday, May 10, 2011
APPL NO 13/104362
ART UNIT 2634 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/224
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US 08750425 Su
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Wei Su (Bel Air, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Wei Su (Bel Air, Maryland)
ABSTRACT A method for identifying the modulation scheme of a software defined radio in real-time without pilot symbols between transmitters and receivers, includes providing a predetermined look-up table (LUT) in the software-defined radio wherein the LUT is prepared by pre-calculating discrete likelihood ratio test (DLRT) function values; storing the pre-calculated DLRT values in said LUT; and indexing the pre-calculated DLRT values by addresses.
FILED Thursday, May 03, 2012
APPL NO 13/462967
ART UNIT 2634 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/324
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US 08750453 Cheng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Chieh C. Cheng (Redlands, California);  David A. Lesyna (Redlands, California);  Michael F. Moyers (Colton, California)
ASSIGNEE(S) Loma Linda University Medical Center (Loma Linda, California)
INVENTOR(S) Chieh C. Cheng (Redlands, California);  David A. Lesyna (Redlands, California);  Michael F. Moyers (Colton, California)
ABSTRACT Apparatus and methods for therapy delivery are disclosed. In one embodiment, a therapy delivery system includes a plurality of movable components including a radiation therapy nozzle and a patient pod for holding a patient, a patient registration module for determining a desired position of at least one of the plurality of movable components, and a motion control module for coordinating the movement of the least one of the plurality of movable components from a current position to the desired position. The motion control module includes a path planning module for simulating at least one projected trajectory of movement of the least one of the plurality of moveable components from the current position to the desired position.
FILED Friday, April 13, 2012
APPL NO 13/447090
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/65
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US 08750520 Sniffen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Communications-Electronics Command (CECOM)
National Security Agency (NSA)
APPLICANT(S) Brian T. Sniffen (Cambridge, Massachusetts);  Joshua Guttman (Newton Centre, Massachusetts);  Ariel Segall (Arlington, Massachusetts);  Amy L. Herzog (Pebble Beach, California)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) Brian T. Sniffen (Cambridge, Massachusetts);  Joshua Guttman (Newton Centre, Massachusetts);  Ariel Segall (Arlington, Massachusetts);  Amy L. Herzog (Pebble Beach, California)
ABSTRACT A system, method, and computer program product are provided for requesting a proof of a security policy in a client system. Additionally, a system, method, and computer program product are provided for proving a security policy to an interrogator system.
FILED Thursday, November 17, 2011
APPL NO 13/298465
ART UNIT 2453 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/32 (20130101)
H04L 9/3221 (20130101) Original (OR) Class
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US 08750595 Stellari
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Franco Stellari (Waldwick, New Jersey)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Franco Stellari (Waldwick, New Jersey)
ABSTRACT A system and method for registering a layout to a measured image includes generating a predictive reference image from a layout design or portion thereof. The predictive reference image is correlated to a measured image obtained from a device having a corresponding structure for the layout design or the portion thereof. A best match transformation is computed between the predictive reference image and the measured image. The layout design or portion thereof is correlated with the measured image based upon the best match transformation.
FILED Wednesday, October 06, 2010
APPL NO 12/898867
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/149
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US 08750717 Yap et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Daniel Yap (Newbury Park, California);  Keyvan Sayyah (Santa Monica, California)
ABSTRACT A spread spectrum waveform generator has a photonic oscillator and an optical heterodyne synthesizer. The photonic oscillator is a multi-tone optical comb generator for generating a series of RF comb lines on an optical carrier. The optical heterodyne synthesizer includes first and second phase-locked lasers, where the first laser feeds the multi-tone optical comb generator and the second laser is a single tone laser whose output light provides a frequency translation reference. At least one photodetector is provided for heterodyning the frequency translation reference with the optical output of the photonic oscillator to generate a spread spectrum waveform. A receiver pre-processor may be provided to operate on the spread spectrum waveform.
FILED Tuesday, August 27, 2013
APPL NO 14/010938
ART UNIT 2634 — Digital Communications
CURRENT CPC
Optical communications
398/158
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US 08750720 Sefler
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) George A. Sefler (Redondo Beach, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) George A. Sefler (Redondo Beach, California)
ABSTRACT Various embodiments are directed to a photonic impulse generator comprising a periodically chirped photonic source a single-frequency photonic source, a photodetector, an optical coupler, and a filter. The optical coupler may be positioned to couple an output of the single-frequency photonic source to an output of the periodically chirped photonic source, resulting in a combined photonic signal. The photodetector may be positioned to receive the combined photonic signal and generate a combined electrical signal. The filter may be in electrical communication with an output of the photodetector to receive the combined electrical signal.
FILED Tuesday, March 01, 2011
APPL NO 13/037814
ART UNIT 2634 — Digital Communications
CURRENT CPC
Optical communications
398/183
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US 08751151 Funk et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) TRX Systems, Inc (Greenbelt, Maryland)
ASSIGNEE(S) TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S) Benjamin E. Funk (Hanover, Maryland);  Jared Napora (Severn, Maryland);  Kamiar Kordari (McLean, Virginia);  Ruchika Verma (Bethesda, Maryland);  Amrit Bandyopadhyay (Washington, District of Columbia);  Carole Teolis (Glenn Dale, Maryland)
ABSTRACT A system and method for recognizing features for location correction in Simultaneous Localization And Mapping operations, thus facilitating longer duration navigation, is provided. The system may detect features from magnetic, inertial, GPS, light sensors, and/or other sensors that can be associated with a location and recognized when revisited. Feature detection may be implemented on a generally portable tracking system, which may facilitate the use of higher sample rate data for more precise localization of features, improved tracking when network communications are unavailable, and improved ability of the tracking system to act as a smart standalone positioning system to provide rich input to higher level navigation algorithms/systems. The system may detect a transition from structured (such as indoors, in caves, etc.) to unstructured (such as outdoor) environments and from pedestrian motion to travel in a vehicle. The system may include an integrated self-tracking unit that can localize and self-correct such localizations.
FILED Thursday, March 28, 2013
APPL NO 13/852649
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/409
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US 08751201 Vavrick
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Daniel J. Vavrick (Fredericksburg, Virginia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Daniel J. Vavrick (Fredericksburg, Virginia)
ABSTRACT A process is provided for characterizing debris, such as predicted from a hydrocode model. The process uses simulation data currently from a CTH hydrocode system to generate a DATAOUT file, but can be easily modified to handle simulation data from other hydrocodes. The debris characterizing process completes iterative calculations to compare cell radii and determine cell connections. Cell connections are continually made to determine and characterize debris pieces. The process includes creating a dynamic scenario from the hydrocode model, producing a SPCTH file, translating the SPCTH file to a DATAOUT file, selectively eliminating materials from the DATAOUT file, reordering the input information in the DATAOUT file, determining connected cells to form single pieces of debris, storing connectivity in an integer array, storing piece information in a cell storage array; and displaying the debris information.
FILED Monday, September 12, 2011
APPL NO 13/199958
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/2
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US 08751209 Henning et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Mark Daniel Henning (Maple Grove, Minnesota);  Michael J. Smith (Forest Hill, Maryland);  Javad Sedehi (Alexandria, Virginia);  William Crocoll (Broadlands, Virginia)
ASSIGNEE(S) Exelis Inc. (McLean, Virginia)
INVENTOR(S) Mark Daniel Henning (Maple Grove, Minnesota);  Michael J. Smith (Forest Hill, Maryland);  Javad Sedehi (Alexandria, Virginia);  William Crocoll (Broadlands, Virginia)
ABSTRACT A method is provided for determining optimum positions in a region for a plurality of sensors that are capable of detecting occurrence of a hazard in the region. The hazard may be a chemical, biological, and/or radiological hazard in solid, liquid or gas form. A “simulation cache” is provided that stores data representing interaction of the hazard with sensors at each of the plurality of candidate locations in the region for each of the plurality of sensor types. Data is then retrieved from the simulation cache as needed for evaluation a particular candidate sensor solution comprising one or more sensors of one or more sensor types at corresponding ones of the candidate locations. An optimization algorithm may be used to select a candidate sensor solution. The data that is retrieved from the simulation cache for a selected candidate sensor solution is evaluated with respect to certain performance criteria. The simulation cache greatly reduces the time required to generate an optimum sensor layout because it separates the hazard modeling and sensor performance modeling from the optimization algorithm. By capturing this data at one time for storage in the simulation cache, it is not necessary to re-run the hazard simulations for each candidate sensor location generated by the optimization algorithm.
FILED Wednesday, March 14, 2007
APPL NO 11/686170
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Data processing: Structural design, modeling, simulation, and emulation
73/13
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US 08751556 Song
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) William S. Song (Lexington, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William S. Song (Lexington, Massachusetts)
ABSTRACT A multiprocessor system and method for performing matrix operations includes multiple processors cooperatively performing a sparse matrix operation. Distributed among the processors are non-zero matrix elements of first and second sparse matrices. Mapped across the processors are the matrix elements of a results matrix. Each processor receives, from the other processors, non-zero matrix elements of the first matrix that had been distributed to those other processors and generates partial results based on the received non-zero matrix elements of the first matrix and on the non-zero matrix elements of the second matrix distributed to that processor. Each processor receives those partial results generated by other processors and associated with the matrix elements of the results matrix mapped to that processor. Each processor generates a final value for each matrix element of the results matrix mapped to that processor based on the partial results generated by that processor and on the partial results received from the other processors associated with that matrix element of the results matrix.
FILED Monday, June 06, 2011
APPL NO 13/153490
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers: Arithmetic processing and calculating
78/607
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US 08751600 Jea et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Tsai-Yang Jea (Poughkeepsie, New York);  Yuan Yuan Nie (Beijing, China PRC)
ABSTRACT In a distributed computing system that includes compute nodes that include computer memory, globally accessible memory space is administered by: for each compute node: mapping a memory region of a predefined size beginning at a predefined address; executing one or more memory management operations within the memory region, including, for each memory management operation executed within the memory region: executing the operation collectively by all compute nodes, where the operation includes a specification of one or more parameters and the parameters are the same across all compute nodes; receiving, by each compute node from a deterministic memory management module in response to the memory management operation, a return value, where the return value is the same across all compute nodes; entering, by each compute node after local completion of the memory management operation, a barrier; and when all compute nodes have entered the barrier, resuming execution.
FILED Tuesday, December 11, 2012
APPL NO 13/710611
ART UNIT 2457 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/216
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US 08751655 Arimilli et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Lakshminarayana B. Arimilli (Austin, Texas);  Bernard C. Drerup (Austin, Texas);  Paul F. Lecocq (Cedar Park, Texas);  Hanhong Xue (Wappingers Falls, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Lakshminarayana B. Arimilli (Austin, Texas);  Bernard C. Drerup (Austin, Texas);  Paul F. Lecocq (Cedar Park, Texas);  Hanhong Xue (Wappingers Falls, New York)
ABSTRACT A mechanism is provided in a collective acceleration unit for performing a collective operation to distribute or collect data among a plurality of participant nodes. The mechanism receives an input collective packet for a collective operation from a neighbor node within a collective tree. The input collective packet comprises a tree identifier and an input data field and wherein the collective tree comprises a plurality of sub trees. The mechanism maps the tree identifier to an index within the collective acceleration unit. The index identifies a portion of resources within the collective acceleration unit and is associated with a set of neighbor nodes in a given sub tree within the collective tree. For each neighbor node the collective acceleration unit stores destination information. The collective acceleration unit performs an operation on the input data field using the portion of resources to effect the collective operation.
FILED Monday, March 29, 2010
APPL NO 12/749100
ART UNIT 2443 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/226
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Department of Energy (DOE) 

US 08745936 Plaisted et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Joshua Reed Plaisted (Oakland, California);  Brian West (San Francisco, California)
ASSIGNEE(S) SunEdison, LLC (St. Peters, Missouri)
INVENTOR(S) Joshua Reed Plaisted (Oakland, California);  Brian West (San Francisco, California)
ABSTRACT A rack assembly is provided for mounting solar modules over an underlying body. The rack assembly may include a plurality of rail structures that are arrangeable over the underlying body to form an overall perimeter for the rack assembly. One or more retention structures may be provided with the plurality of rail structures, where each retention structure is configured to support one or more solar modules at a given height above the underlying body. At least some of the plurality of rail structures are adapted to enable individual rail structures o be sealed over the underlying body so as to constrain air flow underneath the solar modules. Additionally, at least one of (i) one or more of the rail structures, or (ii) the one or more retention structures are adjustable so as to adapt the rack assembly to accommodate solar modules of varying forms or dimensions.
FILED Friday, August 03, 2012
APPL NO 13/566935
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Static structures
052/173.300
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US 08746000 Schultz
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Mark D. Schultz (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Mark D. Schultz (Ossining, New York)
ABSTRACT According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools warm air generated by the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat from the rack of information technology equipment.
FILED Thursday, August 16, 2012
APPL NO 13/587912
ART UNIT 3744 — Static Structures, Supports and Furniture
CURRENT CPC
Refrigeration
062/259.200
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US 08746440 Williamson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Mark A. Williamson (Naperville, Illinois);  Stanley G. Wiedmeyer (Glen Ellyn, Illinois);  James L. Willit (Batavia, Illinois);  Laurel A. Barnes (Chicago, Illinois);  Robert J. Blaskovitz (Lockport, Illinois)
ASSIGNEE(S) GE-Hitachi Nuclear Energy Americas LLC (Wilmington, North Carolina)
INVENTOR(S) Mark A. Williamson (Naperville, Illinois);  Stanley G. Wiedmeyer (Glen Ellyn, Illinois);  James L. Willit (Batavia, Illinois);  Laurel A. Barnes (Chicago, Illinois);  Robert J. Blaskovitz (Lockport, Illinois)
ABSTRACT A continuous recovery system for an electrorefiner system may include a trough having a ridge portion and a furrow portion. The furrow portion may include a first section and a second section. An inlet and exit pipe may be connected to the trough. The inlet pipe may include an outlet opening that opens up to the first section of the furrow portion of the trough. The exit pipe may include an entrance opening that opens up to the second section of the furrow portion of the trough. A chain may extend through the inlet and exit pipes and along the furrow portion of the trough. The chain may be in a continuous loop form. A plurality of flights may be secured to the chain. Accordingly, the desired product may be continuously harvested from the electrorefiner system without having to halt the electrical power and/or remove the cathode and anode assemblies.
FILED Thursday, December 22, 2011
APPL NO 13/335140
ART UNIT 3651 — Material and Article Handling
CURRENT CPC
Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 19/14 (20130101) Original (OR) Class
B65G 45/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08746561 Gladwell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Thomas Scott Gladwell (Albuquerque, New Mexico);  Justin Garretson (Albuquerque, New Mexico);  Clinton G. Hobart (Albuquerque, New Mexico);  Mark J. Monda (St. Louis, Missouri)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Thomas Scott Gladwell (Albuquerque, New Mexico);  Justin Garretson (Albuquerque, New Mexico);  Clinton G. Hobart (Albuquerque, New Mexico);  Mark J. Monda (St. Louis, Missouri)
ABSTRACT A system and method for disrupting at least one component of a suspect object is provided. The system has a source for passing radiation through the suspect object, a grid board positionable adjacent the suspect object (the grid board having a plurality of grid areas, the radiation from the source passing through the grid board), a screen for receiving the radiation passing through the suspect object and generating at least one image, a weapon for deploying a discharge, and a targeting unit for displaying the image of the suspect object and aiming the weapon according to a disruption point on the displayed image and deploying the discharge into the suspect object to disable the suspect object.
FILED Thursday, December 23, 2010
APPL NO 12/977349
ART UNIT 2876 — Optics
CURRENT CPC
Registers
235/404
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US 08746577 Bernhard et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Jennifer T Bernhard (Champaign, Illinois);  Jessica E. Ruyle (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Jennifer T Bernhard (Champaign, Illinois);  Jessica E. Ruyle (Champaign, Illinois)
ABSTRACT An antenna includes a ground plane having a slot. The slot may be miniaturized using a meandered slot structure or other appropriate reactive loading method as an end load to one or both ends of the slot. An edge treatment may be included on one or more edges of the ground plane or a closely spaced reflecting plane. The antenna is structured to transmit or receive a signal independently or in response to electromagnetic radiation.
FILED Tuesday, September 20, 2011
APPL NO 13/200191
ART UNIT 2887 — Optics
CURRENT CPC
Registers
235/492
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US 08747520 Bearden et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Mark D. Bearden (Richland, Washington);  Paul H. Humble (Kennewick, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Mark D. Bearden (Richland, Washington);  Paul H. Humble (Kennewick, Washington)
ABSTRACT The present invention are methods for removing preselected substances from a mixed flue gas stream characterized by cooling said mixed flue gas by direct contact with a quench liquid to condense at least one preselected substance and form a cooled flue gas without substantial ice formation on a heat exchanger. After cooling additional process methods utilizing a cryogenic approach and physical concentration and separation or pressurization and sorbent capture may be utilized to selectively remove these materials from the mixed flue gas resulting in a clean flue gas.
FILED Tuesday, May 03, 2011
APPL NO 13/100135
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Gas separation: Processes
095/41
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747591 Peterson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Kenneth A. Peterson (Albuquerque, New Mexico);  Richard T. Knudson (Los Lunas, New Mexico);  Frank R. Smith (Gardner, Kansas);  Gregory Barner (Overland Park, Kansas)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Kenneth A. Peterson (Albuquerque, New Mexico);  Richard T. Knudson (Los Lunas, New Mexico);  Frank R. Smith (Gardner, Kansas);  Gregory Barner (Overland Park, Kansas)
ABSTRACT Generally annular full tape thickness conductors are formed in single or multiple tape layers, and then stacked to produce an annular solid conductive wall for enclosing an electromagnetic isolation cavity. The conductors may be formed using punch and fill operations, or by flowing conductor-containing material onto the tape edge surfaces that define the interior sidewalls of the cavity.
FILED Friday, July 09, 2010
APPL NO 12/833262
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/89.120
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747630 Gessert et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Timothy A. Gessert (Conifer, Colorado);  Yuki Yoshida (San Jose, California);  Timothy J. Coutts (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Timothy A. Gessert (Conifer, Colorado);  Yuki Yoshida (San Jose, California);  Timothy J. Coutts (Golden, Colorado)
ABSTRACT Transparent conducting oxides and production thereof are disclosed. An exemplary method of producing a transparent conducting oxide (TCO) material may comprise: providing a TCO target doped with either a high-permittivity oxide or a low-permittivity oxide in a process chamber. The method may also comprise depositing a metal oxide on the target in the process chamber to form a thin film having enhanced optical properties without substantially decreasing electrical quality.
FILED Friday, May 30, 2008
APPL NO 12/130788
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemistry: Electrical and wave energy
24/192.290
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747651 Miller et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Douglas J. Miller (North Olmsted, Ohio);  Ching-Feng Chang (Strongsville, Ohio);  Irwin C. Lewis (Oberlin, Ohio);  Richard T. Lewis (Auburn, Ohio)
ASSIGNEE(S) GrafTech International Holdings Inc. (Parma, Ohio)
INVENTOR(S) Douglas J. Miller (North Olmsted, Ohio);  Ching-Feng Chang (Strongsville, Ohio);  Irwin C. Lewis (Oberlin, Ohio);  Richard T. Lewis (Auburn, Ohio)
ABSTRACT A high coking value pitch prepared from coal tar distillate and has a low softening point and a high carbon value while containing substantially no quinoline insolubles is disclosed. The pitch can be used as an impregnant or binder for producing carbon and graphite articles.
FILED Thursday, May 22, 2008
APPL NO 12/154430
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Mineral oils: Processes and products
28/42
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747660 Gordon et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Ceramatec, Inc. (Salt Lake City, Utah)
ASSIGNEE(S) Ceramatec, Inc. (Salt Lake City, Utah)
INVENTOR(S) John Howard Gordon (Salt Lake City, Utah);  Javier Alvare (Cottonwood Heights, Utah)
ABSTRACT A process for upgrading an oil feedstock includes reacting the oil feedstock with a quantity of an alkali metal, wherein the reaction produces solid materials and liquid materials. The solid materials are separated from the liquid materials. The solid materials may be washed and heat treated by heating the materials to a temperature above 400° C. The heat treating occurs in an atmosphere that has low oxygen and water content. Once heat treated, the solid materials are added to a solution comprising a polar solvent, where sulfide, hydrogen sulfide or polysulfide anions dissolve. The solution comprising polar solvent is then added to an electrolytic cell, which during operation, produces alkali metal and sulfur.
FILED Wednesday, January 30, 2013
APPL NO 13/753918
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Mineral oils: Processes and products
28/235
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747673 Ginosar et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Daniel M. Ginosar (Idaho Falls, Idaho);  Daniel S. Wendt (Idaho Falls, Idaho);  Lucia M. Petkovic (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Daniel M. Ginosar (Idaho Falls, Idaho);  Daniel S. Wendt (Idaho Falls, Idaho);  Lucia M. Petkovic (Idaho Falls, Idaho)
ABSTRACT A method of removing a nonpolar solvent from a fluid volume that includes at least one nonpolar compound, such as a fat, an oil or a triglyceride, is provided. The method comprises contacting a fluid volume with an expanding gas to expand the nonpolar solvent and form a gas-expanded solvent. The gas-expanded solvent may have a substantially reduced density in comparison to the at least one nonpolar compound and/or a substantially reduced capacity to solubilize the nonpolar compound, causing the nonpolar compounds to separate from the gas-expanded nonpolar solvent into a separate liquid phase. The liquid phase including the at least one nonpolar compound may be separated from the gas-expanded solvent using conventional techniques. After separation of the liquid phase, at least one of the temperature and pressure may be reduced to separate the nonpolar solvent from the expanding gas such that the nonpolar solvent may be recovered and reused.
FILED Thursday, July 07, 2011
APPL NO 13/177962
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/634
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747694 Perry et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) Robert James Perry (Niskayuna, New York);  Michael Joseph O'Brien (Clifton Park, New York)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Robert James Perry (Niskayuna, New York);  Michael Joseph O'Brien (Clifton Park, New York)
ABSTRACT In accordance with one aspect, the present invention provides a composition which contains the amino-siloxane structures I, or III, as described herein. The composition is useful for the capture of carbon dioxide from process streams. In addition, the present invention provides methods of preparing the amino-siloxane composition. Another aspect of the present invention provides methods for reducing the amount of carbon dioxide in a process stream employing the amino-siloxane compositions of the invention, as species which react with carbon dioxide to form an adduct with carbon dioxide.
FILED Thursday, June 17, 2010
APPL NO 12/817276
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Compositions
252/190
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US 08747786 Visser et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) Ann E. Visser (Aiken, South Carolina);  Nicholas J. Bridges (Aiken, South Carolina)
ASSIGNEE(S) Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Ann E. Visser (Aiken, South Carolina);  Nicholas J. Bridges (Aiken, South Carolina)
ABSTRACT A method for forming nanoparticles containing uranium oxide is described. The method includes combining a uranium-containing feedstock with an ionic liquid to form a mixture and holding the mixture at an elevated temperature for a period of time to form the product nanoparticles. The method can be carried out at low temperatures, for instance less than about 300° C.
FILED Friday, September 07, 2012
APPL NO 13/606558
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/11
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747790 Collins et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Emory D. Collins (Knoxville, Tennessee);  Guillermo D. Delcul (Powell, Tennessee);  Rodney D. Hunt (Harriman, Tennessee);  Jared A. Johnson (Knoxville, Tennessee);  Barry B. Spencer (Knoxville, Tennessee)
ABSTRACT A method for reprocessing spent nuclear fuel from a light water reactor includes the step of reacting spent nuclear fuel in a voloxidation vessel with an oxidizing gas having nitrogen dioxide and oxygen for a period sufficient to generate a solid oxidation product of the spent nuclear fuel. The reacting step includes the step of reacting, in a first zone of the voloxidation vessel, spent nuclear fuel with the oxidizing gas at a temperature ranging from 200-450° C. to form an oxidized reaction product, and regenerating nitrogen dioxide, in a second zone of the voloxidation vessel, by reacting oxidizing gas comprising nitrogen monoxide and oxygen at a temperature ranging from 0-80° C. The first zone and the second zone can be separate. A voloxidation system is also disclosed.
FILED Friday, August 16, 2013
APPL NO 13/969088
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/249
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747801 Bowers et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Michael J. Bowers (Nashville, Tennessee);  James R. McBride (Nashville, Tennessee);  Sandra J. Rosenthal (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Michael J. Bowers (Nashville, Tennessee);  James R. McBride (Nashville, Tennessee);  Sandra J. Rosenthal (Nashville, Tennessee)
ABSTRACT Disclosed herein are methods of preparing inorganic nanoparticles. In one aspect, the methods can comprise heating a reaction mixture comprising a C8 to C20 alkyl- or arylphosphonic acid and a source of cadmium or zinc to a temperature of greater than about 300° C.; adding to the reaction mixture an injection mixture comprising a C2 to C16 trialkyl- or triarylphosphine and a source of selenium, sulfur, or tellurium; and decreasing the temperature of the reaction mixture to less than about 300° C. Also disclosed herein are nanoparticles made from the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, November 16, 2012
APPL NO 13/679924
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/509
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747980 Bikson et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Benjamin Bikson (Newton, Massachusetts);  Stephen Etter (Hamden, Connecticut);  Nathaniel Ching (Middletown, New Jersey)
ASSIGNEE(S) PoroGen Corporation (Woburn, Massachusetts)
INVENTOR(S) Benjamin Bikson (Newton, Massachusetts);  Stephen Etter (Hamden, Connecticut);  Nathaniel Ching (Middletown, New Jersey)
ABSTRACT A hollow fiber device includes a hollow fiber bundle, comprising a plurality of hollow fibers, a first tubesheet and a second tubesheet encapsulating respective distal ends of the hollow fiber bundle. The tubesheets have boreholes in fluid communication with bores of the hollow fibers. In at least one of the tubesheets, the boreholes are formed radially. The hollow fiber device can be utilized in heat exchange, in gas/gas, liquid/liquid and gas/liquid heat transfer, in combined heat and mass transfer and in fluid separation assemblies and processes. The design disclosed herein is light weight and compact and is particularly advantageous when the pressure of a first fluid introduced into the bores of hollow fibers is higher than the pressure on the shell side of the device.
FILED Friday, June 08, 2012
APPL NO 13/492714
ART UNIT 1782 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/36.910
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748147 Shamoo et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Yousif Shamoo (Houston, Texas);  Siyang Sun (Lafayette, Indiana)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Yousif Shamoo (Houston, Texas);  Siyang Sun (Lafayette, Indiana)
ABSTRACT Chimeric proteins comprising a sequence nonspecific single-stranded nucleic-acid-binding domain joined to a catalytic nucleic-acid-modifying domain are provided. Methods comprising contacting a nucleic acid molecule with a chimeric protein, as well as systems comprising a nucleic acid molecule, a chimeric protein, and an aqueous solution are also provided. The joining of sequence nonspecific single-stranded nucleic-acid-binding domain and a catalytic nucleic-acid-modifying domain in chimeric proteins, among other things, may prevent the separation of the two domains due to their weak association and thereby enhances processivity while maintaining fidelity.
FILED Tuesday, November 27, 2007
APPL NO 11/945877
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/194
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748330 Debe et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Mark K. Debe (Stillwater, Minnesota);  Robert L. W. Smithson (Mahtomedi, Minnesota);  Charles J. Studiner, IV (Cottage Grove, Minnesota);  Susan M. Hendricks (Lake Elmo, Minnesota);  Michael J. Kurkowski (White Bear Lake, Minnesota);  Andrew J. L. Steinbach (St. Anthony Village, Minnesota)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) Mark K. Debe (Stillwater, Minnesota);  Robert L. W. Smithson (Mahtomedi, Minnesota);  Charles J. Studiner, IV (Cottage Grove, Minnesota);  Susan M. Hendricks (Lake Elmo, Minnesota);  Michael J. Kurkowski (White Bear Lake, Minnesota);  Andrew J. L. Steinbach (St. Anthony Village, Minnesota)
ABSTRACT This disclosure provides methods of making an enhanced activity nanostructured thin film catalyst by radiation annealing, typically laser annealing, typically under inert atmosphere. Typically the inert gas has a residual oxygen level of 100 ppm. Typically the irradiation has an incident energy fluence of at least 30 mJ/mm2. In some embodiments, the radiation annealing is accomplished by laser annealing. In some embodiments, the nanostructured thin film catalyst is provided on a continuous web.
FILED Tuesday, April 26, 2011
APPL NO 13/643431
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/5
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748349 Goyal et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Amit Goyal (Knoxville, Tennessee);  Sung-Hun Wee (Knoxville, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Amit Goyal (Knoxville, Tennessee);  Sung-Hun Wee (Knoxville, Tennessee)
ABSTRACT A superconducting article includes a substrate having a biaxially textured surface. A biaxially textured buffer layer, which can be a cap layer, is supported by the substrate. The buffer layer includes a double perovskite of the formula A2B′B″O6, where A is rare earth or alkaline earth metal and B′ and B″ are different transition metal cations. A biaxially textured superconductor layer is deposited so as to be supported by the buffer layer. A method of making a superconducting article is also disclosed.
FILED Friday, April 15, 2011
APPL NO 13/088179
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/24 (20130101) Original (OR) Class
H01L 39/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748350 Goyal et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Amit Goyal (Knoxville, Tennessee);  Mariappan Paranthaman (Knoxville, Tennessee);  Sung-Hun Wee (Knoxville, Tennessee)
ASSIGNEE(S) UT-Battelle (Oak Ridge, Tennessee);  University of Tennessee Research Center (Knoxville, Tennessee)
INVENTOR(S) Amit Goyal (Knoxville, Tennessee);  Mariappan Paranthaman (Knoxville, Tennessee);  Sung-Hun Wee (Knoxville, Tennessee)
ABSTRACT A method for making a superconducting article includes the steps of providing a biaxially textured substrate. A seed layer is then deposited. The seed layer includes a double perovskite of the formula A2B′B″O6, where A is rare earth or alkaline earth metal and B′ and B″ are different rare earth or transition metal cations. A superconductor layer is grown epitaxially such that the superconductor layer is supported by the seed layer.
FILED Friday, April 15, 2011
APPL NO 13/088182
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/24 (20130101) Original (OR) Class
H01L 39/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748352 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Qibin Zhang (West Richland, Washington);  Thomas O. Metz (Kennewick, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Qibin Zhang (West Richland, Washington);  Thomas O. Metz (Kennewick, Washington)
ABSTRACT A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.
FILED Wednesday, August 15, 2012
APPL NO 13/586321
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Combinatorial chemistry technology: Method, library, apparatus
56/7
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748537 Naskar et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Amit K. Naskar (Knoxville, Tennessee);  Tomonori Saito (Knoxville, Tennessee);  Joseph M. Pickel (Knoxville, Tennessee);  Frederick S. Baker (Oak Ridge, Tennessee);  Claude Clifford Eberle (Knoxville, Tennessee);  Robert E. Norris (Knoxville, Tennessee);  Jonathan Richard Mielenz (Rockwood, Tennessee)
ABSTRACT The present invention relates to a crosslinked lignin comprising a lignin structure having methylene or ethylene linking groups therein crosslinking between phenyl ring carbon atoms, wherein said crosslinked lignin is crosslinked to an extent that it has a number-average molecular weight of at least 10,000 g/mol, is melt-processible, and has either a glass transition temperature of at least 100° C., or is substantially soluble in a polar organic solvent or aqueous alkaline solution. Thermoplastic copolymers containing the crosslinked lignin are also described. Methods for producing the crosslinked lignin and thermoplastic copolymers are also described.
FILED Monday, October 21, 2013
APPL NO 14/058657
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
525/152
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749629 Baleine et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Erwan Baleine (Orlando, Florida);  Danny M. Sheldon (Chuluota, Florida)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) Erwan Baleine (Orlando, Florida);  Danny M. Sheldon (Chuluota, Florida)
ABSTRACT Method and system for calibrating a thermal radiance map of a turbine component in a combustion environment. At least one spot (18) of material is disposed on a surface of the component. An infrared (IR) imager (14) is arranged so that the spot is within a field of view of the imager to acquire imaging data of the spot. A processor (30) is configured to process the imaging data to generate a sequence of images as a temperature of the combustion environment is increased. A monitor (42, 44) may be coupled to the processor to monitor the sequence of images of to determine an occurrence of a physical change of the spot as the temperature is increased. A calibration module (46) may be configured to assign a first temperature value to the surface of the turbine component when the occurrence of the physical change of the spot is determined.
FILED Wednesday, February 09, 2011
APPL NO 13/023774
ART UNIT 2485 — Recording and Compression
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 2219/37211 (20130101)
G05B 2219/37509 (20130101)

Pictorial Communication, e.g Television
H04N 7/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749949 Caporaso et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) George J. Caporaso (Livermore, California);  Stephen E. Sampayan (Manteca, California);  David M. Sanders (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) George J. Caporaso (Livermore, California);  Stephen E. Sampayan (Manteca, California);  David M. Sanders (Livermore, California)
ABSTRACT In a structure or device having a pair of electrical conductors separated by an insulator across which a voltage is placed, resistive layers are formed around the conductors to force the electric potential within the insulator to distribute more uniformly so as to decrease or eliminate electric field enhancement at the conductor edges. This is done by utilizing the properties of resistive layers to allow the voltage on the electrode to diffuse outwards, reducing the field stress at the conductor edge. Preferably, the resistive layer has a tapered resistivity, with a lower resistivity adjacent to the conductor and a higher resistivity away from the conductor. Generally, a resistive path across the insulator is provided, preferably by providing a resistive region in the bulk of the insulator, with the resistive layer extending over the resistive region.
FILED Monday, October 31, 2011
APPL NO 13/285996
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/312
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749951 Falabella et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Steven Falabella (Livermore, California);  Glenn A. Meyer (Danville, California);  Vincent Tang (Dublin, California);  Gary Guethlein (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (, None)
INVENTOR(S) Steven Falabella (Livermore, California);  Glenn A. Meyer (Danville, California);  Vincent Tang (Dublin, California);  Gary Guethlein (Livermore, California)
ABSTRACT A two-phase mixed media insulator having a dielectric fluid filling the interstices between macro-sized dielectric beads packed into a confined volume, so that the packed dielectric beads inhibit electro-hydrodynamically driven current flows of the dielectric liquid and thereby increase the resistivity and breakdown strength of the two-phase insulator over the dielectric liquid alone. In addition, an electrical apparatus incorporates the two-phase mixed media insulator to insulate between electrical components of different electrical potentials. And a method of electrically insulating between electrical components of different electrical potentials fills a confined volume between the electrical components with the two-phase dielectric composite, so that the macro dielectric beads are packed in the confined volume and interstices formed between the macro dielectric beads are filled with the dielectric liquid.
FILED Friday, March 26, 2010
APPL NO 12/748135
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Electricity: Electrical systems and devices
361/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750459 Cowan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Thomas Cowan (Dresden, Germany);  Steven Malekos (Reno, Nevada);  Grant Korgan (Reno, Nevada);  Jesse Adams (Reno, Nevada);  Yasuhiko Sentoku (Reno, Nevada);  Nathalie LeGalloudec (Livermore, California)
ASSIGNEE(S) Board of Regents of the Nevada System of Higher Education (Reno, Nevada)
INVENTOR(S) Thomas Cowan (Dresden, Germany);  Steven Malekos (Reno, Nevada);  Grant Korgan (Reno, Nevada);  Jesse Adams (Reno, Nevada);  Yasuhiko Sentoku (Reno, Nevada);  Nathalie LeGalloudec (Livermore, California)
ABSTRACT In particular embodiments, the present disclosure provides targets including a metal layer and defining a hollow inner surface. The hollow inner surface has an internal apex. The distance between at least two opposing points of the internal apex is less than about 15 μm. In particular examples, the distance is less than about 1 μm. Particular implementations of the targets are free standing. The targets have a number of disclosed shaped, including cones, pyramids, hemispheres, and capped structures. The present disclosure also provides arrays of such targets. Also provided are methods of forming targets, such as the disclosed targets, using lithographic techniques, such as photolithographic techniques. In particular examples, a target mold is formed from a silicon wafer and then one or more sides of the mold are coated with a target material, such as one or more metals.
FILED Monday, March 12, 2012
APPL NO 13/418003
ART UNIT 2882 — Optics
CURRENT CPC
X-ray or gamma ray systems or devices
378/143
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750653 Peters et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) David W. Peters (Albuquerque, New Mexico);  Paul Davids (Albuquerque, New Mexico);  Darin Leonhardt (Albuquerque, New Mexico);  Jin K. Kim (Albuquerque, New Mexico);  Joel R. Wendt (Albuquerque, New Mexico);  John F. Klem (Albuquerque, New Mexico)
ABSTRACT An exemplary embodiment of the present invention is a photodetector comprising a semiconductor body, a periodically patterned metal nanoantenna disposed on a surface of the semiconductor body, and at least one electrode separate from the nanoantenna. The semiconductor body comprises an active layer in sufficient proximity to the nanoantenna for plasmonic coupling thereto. The nanoantenna is dimensioned to absorb electromagnetic radiation in at least some wavelengths not more than 12 μm that are effective for plasmonic coupling into the active layer. The electrode is part of an electrode arrangement for obtaining a photovoltage or photocurrent in operation under appropriate stimulation.
FILED Friday, April 26, 2013
APPL NO 13/871708
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/12
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US 08751073 Kumar et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Ajith Kuttannair Kumar (Erie, Pennsylvania);  Wolfgang Daum (Erie, Pennsylvania);  Tom Otsubo (Oak Grove, Pennsylvania);  John Erik Hershey (Ballston Lake, New York);  Gerald James Hess (Lenexa, Kansas)
ABSTRACT A system is provided for operating a railway network including a first railway vehicle during a trip along track segments. The system includes a first element for determining travel parameters of the first railway vehicle, a second element for determining travel parameters of a second railway vehicle relative to the track segments to be traversed by the first vehicle during the trip, a processor for receiving information from the first and the second elements and for determining a relationship between occupation of a track segment by the second vehicle and later occupation of the same track segment by the first vehicle and an algorithm embodied within the processor having access to the information to create a trip plan that determines a speed trajectory for the first vehicle. The speed trajectory is responsive to the relationship and further in accordance with one or more operational criteria for the first vehicle.
FILED Friday, January 11, 2013
APPL NO 13/739133
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/19
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US 08751140 Surnilla et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Gopichandra Surnilla (West Bloomfield, Michigan);  Thomas G. Leone (Ypsilanti, Michigan);  Krishnaswamy Venkatesh Prasad (Ann Arbor, Michigan);  Apoorv Agarwal (Clarkston, Michigan);  Brett Stanley Hinds (Clarkston, Michigan)
ASSIGNEE(S) Ford Global Technologies, LLC (Dearborn, Michigan)
INVENTOR(S) Gopichandra Surnilla (West Bloomfield, Michigan);  Thomas G. Leone (Ypsilanti, Michigan);  Krishnaswamy Venkatesh Prasad (Ann Arbor, Michigan);  Apoorv Agarwal (Clarkston, Michigan);  Brett Stanley Hinds (Clarkston, Michigan)
ABSTRACT Methods and systems are provided for facilitating refueling operations in vehicles operating with multiple fuels. A vehicle operator may be assisted in refueling the multiple fuel tanks of the vehicle by being provided one or more refueling profiles that take into account the vehicle's future trip plans, the predicted environmental conditions along a planned route, and the operator's preferences.
FILED Thursday, September 13, 2012
APPL NO 13/614989
ART UNIT 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/123
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US 08751168 Billinge et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Simon Billinge (Brooklyn, New York);  Kenneth Shankland (Reading, United Kingdom);  Norman Shankland (Glasgow, United Kingdom);  Alastair Florence (Glasgow, United Kingdom)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Simon Billinge (Brooklyn, New York);  Kenneth Shankland (Reading, United Kingdom);  Norman Shankland (Glasgow, United Kingdom);  Alastair Florence (Glasgow, United Kingdom)
ABSTRACT The present invention provides, inter alia, methods of characterizing a small molecule organic material, e.g., a drug or a drug product. This method includes subjecting the solid small molecule organic material to x-ray total scattering analysis at a short wavelength, collecting data generated thereby, and mathematically transforming the data to provide a refined set of data.
FILED Friday, May 28, 2010
APPL NO 12/802064
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/28
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US 08751595 Blocksome et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael A. Blocksome (Rochester, Minnesota);  Sameer Kumar (White Plains, New York);  Jeffrey J. Parker (Rochester, Minnesota)
ABSTRACT Completion processing of data communications instructions in a distributed computing environment with computers coupled for data communications through communications adapters and an active messaging interface (‘AMI’), injecting for data communications instructions into slots in an injection FIFO buffer a transfer descriptor, at least some of the instructions specifying callback functions; injecting a completion descriptor for each instruction that specifies a callback function into an injection FIFO buffer slot having a corresponding slot in a pending callback list; listing in the pending callback list callback functions specified by data communications instructions; processing each descriptor in the injection FIFO buffer, setting a bit in a completion bit mask corresponding to the slot in the FIFO where the completion descriptor was injected; and calling by the AMI any callback functions in the pending callback list as indicated by set bits in the completion bit mask.
FILED Monday, November 19, 2012
APPL NO 13/680772
ART UNIT 2457 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/206
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US 08751748 Ahn et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Daniel Ahn (Yorktown Heights, New York);  Luis H. Ceze (Urbana, Illinois);  Alan Gara (Mount Kisco, New York);  Martin Ohmacht (Yorktown Heights, New York);  Zhuang Xiaotong (White Plains, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Daniel Ahn (Yorktown Heights, New York);  Luis H. Ceze (Urbana, Illinois);  Alan Gara (Mount Kisco, New York);  Martin Ohmacht (Yorktown Heights, New York);  Zhuang Xiaotong (White Plains, New York)
ABSTRACT In a parallel processing system with speculative execution, conflict checking occurs in a directory lookup of a cache memory that is shared by all processors. In each case, the same physical memory address will map to the same set of that cache, no matter which processor originated that access. The directory includes a dynamic reader set encoding, indicating what speculative threads have read a particular line. This reader set encoding is used in conflict checking. A bitset encoding is used to specify particular threads that have read the line.
FILED Tuesday, January 18, 2011
APPL NO 13/008583
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/130
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US 08752051 Archer et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Charles J. Archer (Rochester, Minnesota);  Gabor Dozsa (Ardsley, New York);  Joseph D. Ratterman (Seattle, Washington);  Brian E. Smith (Rochester, Minnesota)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Charles J. Archer (Rochester, Minnesota);  Gabor Dozsa (Ardsley, New York);  Joseph D. Ratterman (Seattle, Washington);  Brian E. Smith (Rochester, Minnesota)
ABSTRACT Methods, apparatus, and products are disclosed for performing an allreduce operation using shared memory that include: receiving, by at least one of a plurality of processing cores on a compute node, an instruction to perform an allreduce operation; establishing, by the core that received the instruction, a job status object for specifying a plurality of shared memory allreduce work units, the plurality of shared memory allreduce work units together performing the allreduce operation on the compute node; determining, by an available core on the compute node, a next shared memory allreduce work unit in the job status object; and performing, by that available core on the compute node, that next shared memory allreduce work unit.
FILED Thursday, March 22, 2012
APPL NO 13/427057
ART UNIT 2199 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/52 (20130101)
G06F 9/4843 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08752211 Kalinin et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Sergei V. Kalinin (Knoxville, Tennessee);  Nina Balke (Knoxville, Tennessee);  Albina Y. Borisevich (Knoxville, Tennessee);  Stephen Jesse (Knoxville, Tennessee);  Petro Maksymovych (Knoxville, Tennessee);  Yunseok Kim (Guyeonggi-do, South Korea);  Evgheni Strelcov (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Sergei V. Kalinin (Knoxville, Tennessee);  Nina Balke (Knoxville, Tennessee);  Albina Y. Borisevich (Knoxville, Tennessee);  Stephen Jesse (Knoxville, Tennessee);  Petro Maksymovych (Knoxville, Tennessee);  Yunseok Kim (Guyeonggi-do, South Korea);  Evgheni Strelcov (Oak Ridge, Tennessee)
ABSTRACT An excitation voltage biases an ionic conducting material sample over a nanoscale grid. The bias sweeps a modulated voltage with increasing maximal amplitudes. A current response is measured at grid locations. Current response reversal curves are mapped over maximal amplitudes of the bias cycles. Reversal curves are averaged over the grid for each bias cycle and mapped over maximal bias amplitudes for each bias cycle. Average reversal curve areas are mapped over maximal amplitudes of the bias cycles. Thresholds are determined for onset and ending of electrochemical activity. A predetermined number of bias sweeps may vary in frequency where each sweep has a constant number of cycles and reversal response curves may indicate ionic diffusion kinetics.
FILED Friday, August 03, 2012
APPL NO 13/566327
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM]
850/43
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US PP24537 Abrahamson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Lawrence P. Abrahamson (Marcellus, New York);  Richard F. Kopp (Marietta, New York);  Lawrence B. Smart (Geneva, New York);  Timothy A. Volk (Syracuse, New York)
ASSIGNEE(S) Suny Research Foundation (Albany, New York)
INVENTOR(S) Lawrence P. Abrahamson (Marcellus, New York);  Richard F. Kopp (Marietta, New York);  Lawrence B. Smart (Geneva, New York);  Timothy A. Volk (Syracuse, New York)
ABSTRACT A distinct female cultivar of Salix viminalis×(Salix sachalinensis×Salix miyabeana) named ‘Preble’, characterized by rapid stem growth producing 29% more woody biomass than the average of three current production cultivars (Salix×dasyclados ‘SV1’ (unpatented), Salix sachalinensis ‘SX61’ (unpatented), and Salix miyabeana ‘SX64’ (unpatented)) when grown in the same field for the same length of time (three growing seasons after coppice) in two different trials in Constableville, N.Y. and Middlebury, Vt. ‘Preble’ can be planted from dormant stem cuttings, produces multiple stems after coppice and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested repeatedly after two to four years of growth. ‘Preble’ displays a low incidence of rust disease and is not damaged by potato leafhoppers.
FILED Wednesday, February 29, 2012
APPL NO 13/385672
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/226
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08745853 Grbic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Anthony Grbic (Ann Arbor, Michigan);  Carl Pfeiffer (Milford, Michigan);  Xin Xu (West Windsor, New Jersey);  Stephen Forrest (Ann Arbor, Michigan)
ASSIGNEE(S) Universal Display Corporation (Ewing, New Jersey);  The Regents of the University of Michigan, University of Michigan Office of Technology Transfer (Ann Arbor, Michigan)
INVENTOR(S) Anthony Grbic (Ann Arbor, Michigan);  Carl Pfeiffer (Milford, Michigan);  Xin Xu (West Windsor, New Jersey);  Stephen Forrest (Ann Arbor, Michigan)
ABSTRACT Disclosed herein is a method of fabricating an antenna in which a flexible stamp is formed from a first wafer, the first wafer transferring a pattern to the flexible stamp, in which an antenna substrate is shaped into a three-dimensional contour with a second mold, in which the flexible stamp is positioned in the second mold to deform the flexible stamp into the three-dimensional contour, and in which a metallic layer on the flexible stamp is cold welded to create a set of antenna traces on the antenna substrate in accordance with the pattern. The antenna traces may then be electroplated.
FILED Tuesday, July 05, 2011
APPL NO 13/176053
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/600
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US 08747880 Forgacs et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Gabor Forgacs (Potsdam, New York);  Stephen H. Colbert (Columbia, Missouri);  Bradley A. Hubbard (Columbia, Missouri);  Francoise Marga (Columbia, Missouri);  Dustin Christiansen (Eugene, Oregon)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Gabor Forgacs (Potsdam, New York);  Stephen H. Colbert (Columbia, Missouri);  Bradley A. Hubbard (Columbia, Missouri);  Francoise Marga (Columbia, Missouri);  Dustin Christiansen (Eugene, Oregon)
ABSTRACT An engineered three-dimensional structure includes living cells cohered with each other. The living cells suitably include Schwann cells and at least one other type of cell. The cells accompanying the Schwann cells can suitably be bone marrow stem cells or another type of cell having one or more anti-inflammatory properties. The structure is suitably a graft that facilitates restorative axon growth when the graft is implanted between the proximal and distal stubs of a severed nerve in a living organism. The graft can optionally include a plurality of acellular conduits extending between opposite axial ends of the graft. Bio-printing techniques can be used to assemble a three-dimensional construct that becomes through maturation an axon-guiding graft, by stacking a plurality of multicellular bodies, each of which includes a plurality of living cells cohered to one another to sufficiently to avoid collapsing when the multicellular bodies are stacked to form the structure.
FILED Wednesday, February 02, 2011
APPL NO 13/020000
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/422
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US 08748091 Timp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Physics (PHY)
APPLICANT(S) Gregory Timp (South Bend, Indiana);  Winston Timp (Baltimore, Maryland);  Utkur Mirsaidov (Urbana, Illinois);  Aleksei Aksimentiev (Urbana, Illinois);  Jeffrey Comer (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The John Hopkins University (Baltimore, Maryland)
INVENTOR(S) Gregory Timp (South Bend, Indiana);  Winston Timp (Baltimore, Maryland);  Utkur Mirsaidov (Urbana, Illinois);  Aleksei Aksimentiev (Urbana, Illinois);  Jeffrey Comer (Urbana, Illinois)
ABSTRACT Methods of trapping a deformed portion of a double-stranded polynucleotide in a membrane nanopassage are provided. In an aspect, the membrane has a nanopassage that defines a confine region, wherein the membrane separates a first fluid compartment from a second fluid compartment, and the nanopassage is in fluid communication with the first and second compartments. A polynucleotide is provided to the first fluid compartment and optionally a threshold voltage for the membrane and the polynucleotide is determined. A driving voltage across the membrane that is greater than the threshold voltage is applied to force a portion of the polynucleotide sequence into the nanopassage confine region, and decreased to a holding voltage bias to trap the polynucleotide portion in the nanopassage confine region. In particular, at least one nucleotide base-pair is fixably positioned in the nanopassage confine volume. In further embodiments, any of the trapping methods are used to characterize or sequence double stranded DNA.
FILED Friday, December 17, 2010
APPL NO 12/971240
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4146 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748094 Weitz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) David A. Weitz (Bolton, Massachusetts);  Adam R. Abate (San Francisco, California)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David A. Weitz (Bolton, Massachusetts);  Adam R. Abate (San Francisco, California)
ABSTRACT This invention generally relates to particle-assisted nucleic acid sequencing. In some embodiments, sequencing may be performed in a microfluidic device, which can offer desirable properties, for example, minimal use of reagents, facile scale-up, and/or high throughput. In one embodiment, a target nucleic acid may be exposed to particles having nucleic acid probes. By determining the binding of the particles to the target nucleic acid, the sequence of the target nucleic acid (or at least a portion of the target nucleic acid) can be determined. The target nucleic acid may be encapsulated within a fluidic droplet with the particles having nucleic acid probes, in certain instances. In some cases, the sequence of the target nucleic acid may be determined, based on binding of the particles, using sequencing by hybridization (SBH) algorithms or other known techniques.
FILED Friday, December 18, 2009
APPL NO 13/139326
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748504 Elimelech et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Menachem Elimelech (New Haven, Connecticut);  Chinedum Osuji (Norwalk, Connecticut);  Meagan Mauter (Pittsburgh, Pennsylvania)
ABSTRACT The present invention relates to the development and fabrication of thin-film polymer nanocomposites containing vertically aligned nanomaterials, such as single-walled carbon nanotubes (SWNTs). In certain embodiments, the present invention utilizes liquid crystal mesophases of hexagonally packed cylindrical micelles that orient with their long axes parallel to an applied magnetic field, thereby directing the alignment of the nanomaterials, such as SWNTs, sequestered in the micellar cores. In certain embodiments, the mesophase may be a stable, single-phase material containing monomers that can be polymerized after nanotube alignment to form the nanocomposite polymer.
FILED Thursday, October 11, 2012
APPL NO 13/649472
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
522/71
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748730 Kornfield et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Julia A. Kornfield (Pasadena, California);  Richard C. Flagan (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Julia A. Kornfield (Pasadena, California);  Richard C. Flagan (Pasadena, California)
ABSTRACT Systems and methods for concentrating solar energy without tracking the sun are provided. In one embodiment, the invention relates to a solar collector assembly for collecting and concentrating light for solar cell assemblies, the collector assembly including an array of solar collectors, each including a funnel shaped collector including a side wall defining a tapered opening having a base aperture and an upper aperture, the side wall including an outer surface, and a solar cell assembly positioned at the base aperture, where the outer surface is coated with a material that substantially reflects light, where the upper aperture is wider than the base aperture, where the funnel shaped collector is configured to substantially confine light, incident via the upper aperture, within the funnel shaped collector until the light exits proximate the base aperture, and where the solar cell assembly is configured to capture light exiting the base aperture.
FILED Saturday, March 13, 2010
APPL NO 12/723625
ART UNIT 1758 — Organic Chemistry
CURRENT CPC
Batteries: Thermoelectric and photoelectric
136/246
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US 08748950 Levy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Jeremy Levy (Pittsburgh, Pennsylvania);  Cheng Cen (Pittsburgh, Pennsylvania);  Patrick Irvin (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Jeremy Levy (Pittsburgh, Pennsylvania);  Cheng Cen (Pittsburgh, Pennsylvania);  Patrick Irvin (Pittsburgh, Pennsylvania)
ABSTRACT A reconfigurable device includes a first insulating layer, a second insulating layer, and a nanoscale quasi one- or zero-dimensional electron gas region disposed at an interface between the first and second insulating layers. The device is reconfigurable by applying an external electrical field to the electron gas, thereby changing the conductivity of the electron gas region. A method for forming and erasing nanoscale-conducting structures employs tools, such as the tip of a conducting atomic force microscope (AFM), to form local electric fields. The method allows both isolated and continuous conducting features to be formed with a length well below 5 nm.
FILED Wednesday, November 17, 2010
APPL NO 13/509538
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/288
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749421 Kurchuk et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Mariya Kurchuk (Bridgewater, New Jersey);  Colin Weltin-Wu (Berkeley, California);  Yannis Tsividis (New York, New York);  Dominique Morche (Meylan, France);  David Lachartre (Montbonnot, France)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York);  Commissariat a l'Energie Atomique (Paris, France)
INVENTOR(S) Mariya Kurchuk (Bridgewater, New Jersey);  Colin Weltin-Wu (Berkeley, California);  Yannis Tsividis (New York, New York);  Dominique Morche (Meylan, France);  David Lachartre (Montbonnot, France)
ABSTRACT Systems, devices, and methods for continuous-time digital signal processing and signal representation are disclosed. This includes a continuous-time analog-to-digital converter that is configured to receive an analog signal and convert it to a continuous-time digital signal without using a clock or any type of sampling. This A/D conversion can include a per-level representation and a per-edge representation of the analog signal to produce a digital signal. The digital signal can then be processed in a continuous-time signal processor. The continuous time signal representation and processing can have benefits such a providing filters in high frequency applications where sampling is not practical.
FILED Tuesday, October 12, 2010
APPL NO 13/501197
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Coded data generation or conversion
341/155
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749619 Kirmani et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Ahmed Kirmani (Cambridge, Massachusetts);  Ramesh Raskar (Cambridge, Massachusetts);  James Davis (Los Gatos, California)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ahmed Kirmani (Cambridge, Massachusetts);  Ramesh Raskar (Cambridge, Massachusetts);  James Davis (Los Gatos, California)
ABSTRACT In illustrative implementations of this invention, multi-path analysis of transient illumination is used to reconstruct scene geometry, even of objects that are occluded from the camera. An ultrafast camera system is used. It comprises a photo-sensor (e.g., accurate in the picosecond range), a pulsed illumination source (e.g. a femtosecond laser) and a processor. The camera emits a very brief light pulse that strikes a surface and bounces. Depending on the path taken, part of the light may return to the camera after one, two, three or more bounces. The photo-sensor captures the returning light bounces in a three-dimensional time image I(x,y,t) for each pixel. The camera takes different angular samples from the same viewpoint, recording a five-dimensional STIR (Space Time Impulse Response). A processor analyzes onset information in the STIR to estimate pairwise distances between patches in the scene, and then employs isometric embedding to estimate patch coordinates.
FILED Wednesday, September 29, 2010
APPL NO 12/893863
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/481 (20130101) Original (OR) Class
G01S 7/4865 (20130101)
G01S 17/89 (20130101)

Pictorial Communication, e.g Television
H04N 3/02 (20130101)
H04N 5/2256 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08749871 Montoya et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Juan C. Montoya (Belmont, Massachusetts);  Steven J. Spector (Lexington, Massachusetts);  Reuel Swint (Billerica, Massachusetts);  Caroline A. Ross (Arlington, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Juan C. Montoya (Belmont, Massachusetts);  Steven J. Spector (Lexington, Massachusetts);  Reuel Swint (Billerica, Massachusetts);  Caroline A. Ross (Arlington, Massachusetts)
ABSTRACT An optical structure for generating nonreciprocal loss is provided that includes a first substrate layer and a magneto-optical layer positioned on the first substrate layer. The magneto-optical layer achieves nonreciprocity with application of an external magnetic field so as to produce resonantly enhanced nonreciprocal loss.
FILED Wednesday, March 07, 2012
APPL NO 13/414289
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/093 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750020 Lu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Wei Lu (Ann Arbor, Michigan);  Sung Hyun Jo (Sunnyvale, California)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Wei Lu (Ann Arbor, Michigan);  Sung Hyun Jo (Sunnyvale, California)
ABSTRACT A method of suppressing propagation of leakage current in an array of switching devices. The method includes providing a dielectric breakdown element integrally and serially connected to a switching element within each of the switching device. A read voltage (for example) is applied to a selected cell. The propagation of leakage current is suppressed by each of the dielectric breakdown element in unselected cells in the array. The read voltage is sufficient to cause breakdown in the selected cells but insufficient to cause breakdown in the serially connected, unselected cells in a specific embodiment. Methods to fabricate of such devices and to program, to erase and to read the device are provided.
FILED Monday, January 07, 2013
APPL NO 13/735814
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/148
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08751843 Meisner et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) David Meisner (Mill Valley, California);  Thomas F. Wenisch (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) David Meisner (Mill Valley, California);  Thomas F. Wenisch (Ann Arbor, Michigan)
ABSTRACT A power management method for use by a blade server or other networked computer having a CPU, memory, network interface, and timer. The method includes monitoring processes in the computer, determining that the computer has become idle, and switching the CPU and memory from an active state to a low power state while maintaining the network interface and timer in an active state. Power management for multicore processors is also provided. A power supply system can be used for providing shared power to groups of the networked computers that each have a similar active power demand. Each PSU in the power supply system is capable of supplying the active power demand at an efficiency greater than a preselected desired minimum efficiency. Changes in power requirements resulting from a computer switching between low power and active states can be accommodated by switching a single PSU into or out of the system.
FILED Wednesday, December 16, 2009
APPL NO 13/139769
ART UNIT 2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Support
713/323
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08752011 Dewan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Prasun Dewan (Chapel Hill, North Carolina);  Olufisayo Omojokun (Atlanta, Georgia)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Prasun Dewan (Chapel Hill, North Carolina);  Olufisayo Omojokun (Atlanta, Georgia)
ABSTRACT Methods, systems and computer readable media for automatically generating customizable user interfaces using programming patterns are disclosed. According to one method, application objects of an application computer program are analyzed to identify programming patterns. Each programming pattern is a relationship among signatures of application methods in one of the application objects. The signatures of the application methods include public interfaces of the application methods. A user interface is automatically generated for the computer program. Automatically generating a user interface includes providing for at least one of a user and a programmer of the computer program to customize mappings between the application objects and user interface elements, where the user interface elements include at least one of user interface widgets and speech grammar rules.
FILED Thursday, March 20, 2008
APPL NO 12/532327
ART UNIT 2199 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/113
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Department of Agriculture (USDA) 

US 08747823 Cardamone et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Jeanette M. Cardamone (Lafayette Hill, Pennsylvania);  Paquita Erazo-Majewicz (Landenberg, Pennsylvania);  Nabil Naouli (Wilmington, Delaware)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Jeanette M. Cardamone (Lafayette Hill, Pennsylvania);  Paquita Erazo-Majewicz (Landenberg, Pennsylvania);  Nabil Naouli (Wilmington, Delaware)
ABSTRACT A composition containing sulfonated keratin with molecular weight distribution of about 96.8% 100 kDa to 100 Da and about 3.2% 250 kDa to 100 kDa, at least one cationic surfactant, and optionally an aqueous carrier. Generally the keratin is produced by a method involving treating wool with about 0.5 to about 1.0N NaOH in a bath volume:wool weight of about 5:1 to about 10:1 at about 40° C. to about 65° C. for about 4 to about 8 hours with dosing about every 1 to 3 hours with about 1% to about 10% by weight of bath of hydrogen peroxide. Also a method for treating a keratin based substrate involving contacting or applying the substrate (e.g., hair) with the composition.
FILED Friday, August 10, 2012
APPL NO 13/571619
ART UNIT 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/70.140
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747859 Mengeling et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) William L. Mengeling (Ames, Iowa);  Ann Vorwald (Ames, Iowa);  Kelly Lager (Neveda, Iowa);  Mike Roof (Ames, Iowa);  Kelly Burkhart (Radcliffe, Iowa);  David E. Gorcyca (St. Joseph, Missouri)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia);  Boehringer Ingelheim Vetmedica, Inc. (St. Joseph, Missouri)
INVENTOR(S) William L. Mengeling (Ames, Iowa);  Ann Vorwald (Ames, Iowa);  Kelly Lager (Neveda, Iowa);  Mike Roof (Ames, Iowa);  Kelly Burkhart (Radcliffe, Iowa);  David E. Gorcyca (St. Joseph, Missouri)
ABSTRACT Substantially avirulent forms of atypical porcine reproductive and respiratory syndrome (PRRS) virus and corresponding vaccines are provided which result from cell culture passaging of virulent forms of PRRS. The resultant avirulent atypical PRRS virus is useful as a vaccine in that PRRS specific antibody response is elicited by inoculation of host animals, thereby conferring effective immunity against both previously known strains of PRRS virus and newly isolated atypical PRRS virus strains. The preferred passaging technique ensures that the virus remains in a logarithmic growth phase substantially throughout the process, which minimizes the time required to achieve attenuation. The present invention also provides diagnostic testing methods which can differentiate between animals infected with field strains and attenuated strains of PRRSV.
FILED Friday, February 20, 2009
APPL NO 12/389558
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/204.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748152 Hector et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Ronald E. Hector (Washington, Illinois);  Bruce S. Dien (Peoria, Illinois);  Michael A. Cotta (Edelstein, Illinois)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Ronald E. Hector (Washington, Illinois);  Bruce S. Dien (Peoria, Illinois);  Michael A. Cotta (Edelstein, Illinois)
ABSTRACT A xylose isomerase (XI) enzyme which exhibits increased activity and affinity for xylose is produced by strain TC2-24 of the rumen bacterium, Prevotella ruminicola. The gene encoding this enzyme may be used to produce improved recombinant yeast capable of utilizing xylose. The recombinant yeast are preferably transformed with heterologous polynucleotide sequences coding both the P. ruminicola XI, and the xylulokinase (XKS) of a Prevotella species. Yeast transformed with the polynucleotide sequences coding both of these XI and XKS exhibit significantly increased xylose utilization and cell growth on a culture medium containing xylose as the sole carbon source, in comparison to yeast transformed with XKS and XI from other sources.
FILED Friday, September 14, 2012
APPL NO 13/616629
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/234
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748641 Ngo et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Helen Ngo (North Wales, Pennsylvania);  Thomas A. Foglia (Lafayette Hill, Pennsylvania)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Helen Ngo (North Wales, Pennsylvania);  Thomas A. Foglia (Lafayette Hill, Pennsylvania)
ABSTRACT A process for preparing saturated branched chain fatty acids or alkyl esters thereof involving subjecting unsaturated fatty acids having 10 to 25 carbon atoms, alkyl esters thereof or mixtures thereof to a skeletal isomerization reaction in the presence of water or a lower alcohol at a temperature of about 240° C. to about 280° C. using a combination of a stericly hindered Lewis base and zeolite as a Brönsted or Lewis acid catalyst, and isolating saturated branched chain fatty acids or alkyl esters thereof or mixtures thereof from the reaction mixture obtained by the skeletal isomerization reaction. The yield of said saturated branched chain fatty acids is ≧70 wt %. The stericly hindered Lewis base is a tertiary amine or phosphine with linear or branched C1 to C6 alkyl or phenyl groups attached thereto.
FILED Wednesday, May 05, 2010
APPL NO 12/774347
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Organic compounds
554/142
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US 08748696 Rathinasabapathi et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Bala Rathinasabapathi (Gainesville, Florida);  Walid Mohamed Fouad (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Bala Rathinasabapathi (Gainesville, Florida);  Walid Mohamed Fouad (Gainesville, Florida)
ABSTRACT The present invention provides methods and compositions for improving biomass, as well as, the drought resistance of plants. More specifically, the present invention utilizes expression of aspartate carboxylase in plants and plant cells.
FILED Tuesday, December 08, 2009
APPL NO 12/633213
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/278
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US PP24537 Abrahamson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Lawrence P. Abrahamson (Marcellus, New York);  Richard F. Kopp (Marietta, New York);  Lawrence B. Smart (Geneva, New York);  Timothy A. Volk (Syracuse, New York)
ASSIGNEE(S) Suny Research Foundation (Albany, New York)
INVENTOR(S) Lawrence P. Abrahamson (Marcellus, New York);  Richard F. Kopp (Marietta, New York);  Lawrence B. Smart (Geneva, New York);  Timothy A. Volk (Syracuse, New York)
ABSTRACT A distinct female cultivar of Salix viminalis×(Salix sachalinensis×Salix miyabeana) named ‘Preble’, characterized by rapid stem growth producing 29% more woody biomass than the average of three current production cultivars (Salix×dasyclados ‘SV1’ (unpatented), Salix sachalinensis ‘SX61’ (unpatented), and Salix miyabeana ‘SX64’ (unpatented)) when grown in the same field for the same length of time (three growing seasons after coppice) in two different trials in Constableville, N.Y. and Middlebury, Vt. ‘Preble’ can be planted from dormant stem cuttings, produces multiple stems after coppice and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested repeatedly after two to four years of growth. ‘Preble’ displays a low incidence of rust disease and is not damaged by potato leafhoppers.
FILED Wednesday, February 29, 2012
APPL NO 13/385672
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/226
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 08746076 Rogge et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Matthew D. Rogge (Norfolk, Virginia);  Jason P. Moore (Yorktown, Virginia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Matthew D. Rogge (Norfolk, Virginia);  Jason P. Moore (Yorktown, Virginia)
ABSTRACT Shape of a multi-core optical fiber is determined by positioning the fiber in an arbitrary initial shape and measuring strain over the fiber's length using strain sensors. A three-coordinate p-vector is defined for each core as a function of the distance of the corresponding cores from a center point of the fiber and a bending angle of the cores. The method includes calculating, via a controller, an applied strain value of the fiber using the p-vector and the measured strain for each core, and calculating strain due to bending as a function of the measured and the applied strain values. Additionally, an apparent local curvature vector is defined for each core as a function of the calculated strain due to bending. Curvature and bend direction are calculated using the apparent local curvature vector, and fiber shape is determined via the controller using the calculated curvature and bend direction.
FILED Wednesday, August 22, 2012
APPL NO 13/591320
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08746357 Butz et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) James R. Butz (Lakewood, Colorado);  Craig S. Turchi (Lakewood, Colorado);  Amanda Kimball (Lakewood, Colorado);  Thomas McKinnon (Boulder, Colorado);  Edward P. Riedel (Boulder, Colorado)
ASSIGNEE(S) ADA Technologies, Inc. (Littleton, Colorado);  Colorado School of Mines (Golden, Colorado)
INVENTOR(S) James R. Butz (Lakewood, Colorado);  Craig S. Turchi (Lakewood, Colorado);  Amanda Kimball (Lakewood, Colorado);  Thomas McKinnon (Boulder, Colorado);  Edward P. Riedel (Boulder, Colorado)
ABSTRACT The present invention is directed to a suppression system in which a carrier gas and suppression liquid are contained in a common containment vessel and separated by a separation member. The separation is one or more of movable, deformable, or shape changing in response to pressure exerted by the stored gas.
FILED Friday, October 19, 2007
APPL NO 11/875494
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Fire extinguishers
169/46
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748046 Smart et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Marshall C. Smart (Studio City, California);  Ratnakumar V. Bugga (Arcadia, California);  G. K. Surya Prakash (Hacienda Heights, California);  Kiah Smith (South Pasadena, California);  Pooja Bhalla (Hercules, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California);  University of Southern California (Los Angeles, California)
INVENTOR(S) Marshall C. Smart (Studio City, California);  Ratnakumar V. Bugga (Arcadia, California);  G. K. Surya Prakash (Hacienda Heights, California);  Kiah Smith (South Pasadena, California);  Pooja Bhalla (Hercules, California)
ABSTRACT An embodiment lithium-ion battery comprising a lithium-ion electrolyte of ethylene carbonate; ethyl methyl carbonate; and at least one solvent selected from the group consisting of trifluoroethyl butyrate, ethyl trifluoroacetate, trifluoroethyl acetate, methyl pentafluoropropionate, and 2,2,2-trifluoroethyl propionate. Other embodiments are described and claimed.
FILED Friday, January 25, 2008
APPL NO 12/011462
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08748822 Gerecht et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Goddard Space Flight Center (GSFC)
APPLICANT(S) Eyal Gerecht (Westminster, Colorado);  David F. Plusquellic (Gaithersburg, Maryland);  Kevin O. Douglass (Columbia, Maryland)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Eyal Gerecht (Westminster, Colorado);  David F. Plusquellic (Gaithersburg, Maryland);  Kevin O. Douglass (Columbia, Maryland)
ABSTRACT Terahertz spectroscopy methods that are fast and have excellent spectral resolution and that do not require background correction of the instrument response without sample are disclosed. In one instance, the methods include phase coherent chirp pulse generation and phase coherent detection.
FILED Tuesday, January 10, 2012
APPL NO 13/346999
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/339.70
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 08746310 Wason et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S) John Wason (Troy, New York);  John T. Wen (Melrose, New York);  Jason Gorman (Silver Spring, Maryland);  Nicholas Dagalakis (Potomac, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Commerce, The National Instutute of Standards and Technology (Washington, District of Columbia)
INVENTOR(S) John Wason (Troy, New York);  John T. Wen (Melrose, New York);  Jason Gorman (Silver Spring, Maryland);  Nicholas Dagalakis (Potomac, Maryland)
ABSTRACT A microassembly method and system utilizing multiple probes. Multiple manipulation actuators can be utilized for maintaining/holding one or more probes and an assembly substrate. Multiple microscope cameras can be configured to provide three distinct workspace configurations. At the center of each manipulation actuator is a die stage, which supports the assembly substrate upon which parts are assembled. A glue dispenser can also provide glue to a part prior to placement.
FILED Friday, May 11, 2012
APPL NO 13/469479
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/378
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08747552 Slack et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Glen A. Slack (Scotia, New York);  Leo J. Schowalter (Latham, New York)
ASSIGNEE(S) Crystal IS, Inc. (Green Island, New York)
INVENTOR(S) Glen A. Slack (Scotia, New York);  Leo J. Schowalter (Latham, New York)
ABSTRACT Fabrication of doped AlN crystals and/or AlGaN epitaxial layers with high conductivity and mobility is accomplished by, for example, forming mixed crystals including a plurality of impurity species and electrically activating at least a portion of the crystal.
FILED Friday, December 18, 2009
APPL NO 12/642182
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/81
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08750385 Dai et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Jiwang Dai (Princeton Junction, New Jersey);  John Qiang Li (Montgomery, New Jersey);  Alan Jay Stein (Princeton Junction, New Jersey)
ASSIGNEE(S) Thomson Research Funding (Indianapolis, Indiana)
INVENTOR(S) Jiwang Dai (Princeton Junction, New Jersey);  John Qiang Li (Montgomery, New Jersey);  Alan Jay Stein (Princeton Junction, New Jersey)
ABSTRACT A system and method for recovering from data loss are described including monitoring a first bit rate video data bit stream to determine if there is frame loss or damage, multiplexing decoding parameters of a second bit rate video data bit stream, the second bit rate video data bit stream and the first bit rate video data bit stream, if there is frame loss or damage, demultiplexing the first bit rate video data bit stream and the second bit rate video data bit stream, decoding the first bit rate video data bit stream, removing damaged frames from the first bit rate video data bit stream, decoding the second bit rate video data bit stream, up-sampling frames from said processed second bit rate video data bit stream if said processed second bit rate video data bit stream has a lower resolution than said processed first bit rate video data bit stream and merging frames from the second bit rate video data bit stream and the first bit rate video data bit stream.
FILED Wednesday, December 20, 2006
APPL NO 12/448291
ART UNIT 2483 — Recording and Compression
CURRENT CPC
Pulse or digital communications
375/240.250
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 08751169 Swayze et al.
FUNDED BY
Department of the Interior (DOI)
APPLICANT(S) Gregg A. Swayze (Littleton, Colorado);  Heather A. Lowers (Golden, Colorado);  Roger N. Clark (Lakewood, Colorado)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Department of the Interior (Washington, District of Columbia)
INVENTOR(S) Gregg A. Swayze (Littleton, Colorado);  Heather A. Lowers (Golden, Colorado);  Roger N. Clark (Lakewood, Colorado)
ABSTRACT A method for identifying the source of vermiculite insulation in situ using a portable spectrometer with a light-emitting contact probe and a personal computer. Identification is accomplished using NIR reflectance spectroscopy and absorption band depth ratios to differentiate between vermiculite sources and to test for the presence of amphibole, talc, or serpentine contaminants in vermiculite insulation.
FILED Wednesday, September 28, 2011
APPL NO 13/247682
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/20 (20130101) Original (OR) Class
C04B 14/38 (20130101)
C04B 14/202 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08750520 Sniffen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Communications-Electronics Command (CECOM)
National Security Agency (NSA)
APPLICANT(S) Brian T. Sniffen (Cambridge, Massachusetts);  Joshua Guttman (Newton Centre, Massachusetts);  Ariel Segall (Arlington, Massachusetts);  Amy L. Herzog (Pebble Beach, California)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) Brian T. Sniffen (Cambridge, Massachusetts);  Joshua Guttman (Newton Centre, Massachusetts);  Ariel Segall (Arlington, Massachusetts);  Amy L. Herzog (Pebble Beach, California)
ABSTRACT A system, method, and computer program product are provided for requesting a proof of a security policy in a client system. Additionally, a system, method, and computer program product are provided for proving a security policy to an interrogator system.
FILED Thursday, November 17, 2011
APPL NO 13/298465
ART UNIT 2453 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/32 (20130101)
H04L 9/3221 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 08748192 Tian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
U.S. State Government
State of Arizona
APPLICANT(S) Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Yanqing Tian (Chandler, Arizona);  Weiwen Zhang (Chandler, Arizona);  Deirdre Meldrum (Phoenix, Arizona);  Hongguang Lu (Harbin, China PRC);  Yuguang Jin (Gilbert, Arizona);  Mark Holl (Tempe, Arizona)
ABSTRACT The present invention relates to an optical fluorescence dual sensor comprising a probe for sensing pH, a probe for sensing oxygen, an intra-reference probe and a matrix. The present invention also relates to methods of preparing an optical fluorescence dual sensor and methods of using them.
FILED Wednesday, October 24, 2012
APPL NO 13/659821
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Chemistry: Analytical and immunological testing
436/136
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08748161 Kuehnle et al.
FUNDED BY
APPLICANT(S) Adelheid R. Kuehnle (Honolulu, Hawaii);  Norie Anne B. Nolasco (Waipahu, Hawaii)
ASSIGNEE(S) Kuehnle AgroSystems, Inc. (Honolulu, Hawaii)
INVENTOR(S) Adelheid R. Kuehnle (Honolulu, Hawaii);  Norie Anne B. Nolasco (Waipahu, Hawaii)
ABSTRACT The subject invention relates to novel methods for treating microbial biomass and uses thereof. In particular, this invention provides methods for production of lipids using hydrophobic ionic liquid solutions, and subsequent uses of biomass components in food, biofuels, and as chemical precursors. Further, this invention provides methods for recovering the ionic liquids using an antisolvent, thus enabling subsequent reuse of the ionic liquids.
FILED Wednesday, November 24, 2010
APPL NO 12/954141
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/257.100
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 10, 2014.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140610.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital