FedInvent™ Patents
Patent Details for Tuesday, June 10, 2014
This page was updated on Monday, March 27, 2023 at 04:01 AM GMT
Department of Health and Human Services (HHS)
US 08746999 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Mark E. Davis (Pasadena, California); Akinleye Alabi (Cambridge, Massachusetts) |
ABSTRACT | Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems. |
FILED | Thursday, March 28, 2013 |
APPL NO | 13/852397 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Typewriting machines 4/489 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747294 | Lipari et al. |
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APPLICANT(S) | Christopher William Lipari (Jacksonville, Florida); Annabelle Rodriguez (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Christopher William Lipari (Jacksonville, Florida); Annabelle Rodriguez (Baltimore, Maryland) |
ABSTRACT | The present invention relates, e.g., to a method for predicting the embryonic progression of a preimplantation embryo, comprising measuring in the insemination medium (IM) in which an oocyte was fertilized and subsequently incubated in vitro, thereby generating a pre-implantation embryo, at 18-24 hrs post fertilization, the levels of nitric oxide metabolites (NOx) in the insemination medium (IM), wherein a level of NOx of at least about 1.3 μM indicates that the preimplantation embryo is likely to progress to the blastocyst stage by culture day (CD) 5. |
FILED | Friday, October 31, 2008 |
APPL NO | 12/740800 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/435 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747382 | D'Souza et al. |
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APPLICANT(S) | Warren D'Souza (Timonium, Maryland); Hao Zhang (Baltimore, Maryland); Kathleen Malinowski (Annapolis, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Warren D'Souza (Timonium, Maryland); Hao Zhang (Baltimore, Maryland); Kathleen Malinowski (Annapolis, Maryland) |
ABSTRACT | One embodiment includes a method of predicting a position of a target site inside a body using surrogates is provided. The method includes transforming surrogate measurements and target positions into different representations by applying an operator, establishing a special relationship between the transformed surrogate measurements and the transformed target positions, and continuously predicting the target position from the transformed surrogate measurements and the established special relationship. |
FILED | Wednesday, June 29, 2011 |
APPL NO | 13/172010 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Surgery 64/500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747669 | Bonner et al. |
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APPLICANT(S) | Alex G. Bonner (Lexington, Massachusetts); Gaston de los Reyes (Somerville, Massachusetts) |
ASSIGNEE(S) | SPF Innovations, LLC (Somerville, Massachusetts) |
INVENTOR(S) | Alex G. Bonner (Lexington, Massachusetts); Gaston de los Reyes (Somerville, Massachusetts) |
ABSTRACT | A separation module and method are disclosed for processing a liquid sample and providing high conversion by operating a single-pass tangential-flow process without a recirculation loop. In one embodiment, the separation module includes three reservoirs and has at least one long, thin channel with a large ratio of channel membrane area to: channel void volume; volume of a sample feed reservoir; and volume of the feed sample. In another embodiment, the separation module includes an external feed reservoir, an external retentate reservoir fluidly and a first vacuum source adapted to apply a first vacuum to the separation element disposed within the housing. The single-pass TFF separation element and single-pass process provides high conversion while operating with relatively low pressure sources. Certain embodiments disclosed herein can be used for the separation of blood. |
FILED | Sunday, August 15, 2010 |
APPL NO | 12/856677 |
ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Liquid purification or separation 210/321.600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747801 | Bowers et al. |
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APPLICANT(S) | Michael J. Bowers (Nashville, Tennessee); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Michael J. Bowers (Nashville, Tennessee); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ABSTRACT | Disclosed herein are methods of preparing inorganic nanoparticles. In one aspect, the methods can comprise heating a reaction mixture comprising a C8 to C20 alkyl- or arylphosphonic acid and a source of cadmium or zinc to a temperature of greater than about 300° C.; adding to the reaction mixture an injection mixture comprising a C2 to C16 trialkyl- or triarylphosphine and a source of selenium, sulfur, or tellurium; and decreasing the temperature of the reaction mixture to less than about 300° C. Also disclosed herein are nanoparticles made from the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
FILED | Friday, November 16, 2012 |
APPL NO | 13/679924 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/509 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747810 | Mahmood et al. |
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APPLICANT(S) | Ashfaq Mahmood (Newton Center, Massachusetts); Alun G. Jones (Newton Center, Massachusetts); Naengnoi Limpa-Amara (Cambridge, Massachusetts); Yijie Peng (Belmont, Massachusetts); Zeynep Akgun (Boston, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Ashfaq Mahmood (Newton Center, Massachusetts); Alun G. Jones (Newton Center, Massachusetts); Naengnoi Limpa-Amara (Cambridge, Massachusetts); Yijie Peng (Belmont, Massachusetts); Zeynep Akgun (Boston, Massachusetts) |
ABSTRACT | The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled metal complexes, particularly tissues, organs, or tumors which express certain receptors to which the compounds or complexes of the invention have an affinity. The present invention also relates to methods of treating cancer, particularly those cancer lines which express certain receptors to which the compounds or complexes of the invention have an affinity. In yet another embodiment, the present invention provides methods of imaging and/or inhibiting receptors or neuroreceptors using compounds or complexes of the invention which have an affinity for the receptor or neuroreceptor to be imaged and/or inhibited. |
FILED | Tuesday, December 13, 2011 |
APPL NO | 13/325051 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) Original (OR) Class A61K 51/02 (20130101) A61K 51/04 (20130101) A61K 2123/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747843 | Giroir et al. |
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APPLICANT(S) | Brett P. Giroir (Vienna, Virginia); Monte S. Willis (Chapel Hill, North Carolina); Vidal F. De La Cruz, Jr. (Phoenixville, Pennsylvania); Thais M. Sielecki-Dzurdz (Kennett Square, Pennsylvania) |
ASSIGNEE(S) | Baxter International, Inc. (Deerfield, Illinois); Baxter Healthcare SA (Glattpark, Opfikon, Switzerland); Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Brett P. Giroir (Vienna, Virginia); Monte S. Willis (Chapel Hill, North Carolina); Vidal F. De La Cruz, Jr. (Phoenixville, Pennsylvania); Thais M. Sielecki-Dzurdz (Kennett Square, Pennsylvania) |
ABSTRACT | One embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount of at least one anti-MIF antibody; and at least one pharmaceutically acceptable carrier. Another embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount at least one anti-CD74 antibody; and at least one pharmaceutically acceptable carrier. Another embodiment of the present invention relates to a pharmaceutical composition, which includes a therapeutically effective amount of at least one anti-TNFR antibody; a therapeutically effective amount of at least one anti-MIF antibody; and at least one pharmaceutically acceptable carrier. Other embodiments of the present invention relate to methods of treating or preventing cardiac dysfunction, cardiodepression, burn injury-associated cardiac dysfunction, improving cardiac function in a subject following acute myocardial infarction, and identifying an MIF inhibitor. |
FILED | Wednesday, October 31, 2007 |
APPL NO | 11/932909 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747844 | Salvemini |
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FUNDED BY |
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APPLICANT(S) | Daniela Salvemini (Chesterfield, Missouri) |
ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
INVENTOR(S) | Daniela Salvemini (Chesterfield, Missouri) |
ABSTRACT | The invention relates to methods for treating pain disorders including neuropathic and inflammatory pain and to methods to reduce or eliminate nociceptive tolerance induced by opiate analgesic use by administering an agent that suppresses or blocks S1P biological activity. |
FILED | Monday, July 25, 2011 |
APPL NO | 13/189954 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747846 | Spellberg et al. |
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APPLICANT(S) | Brad J. Spellberg (Rancho Palos Verdes, California); Lin Lin (Rancho Palos Verdes, California); Ashraf Ibrahim (Irvine, California); Guanpingsheng Luo (Torrance, California) |
ASSIGNEE(S) | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (Torrance, California) |
INVENTOR(S) | Brad J. Spellberg (Rancho Palos Verdes, California); Lin Lin (Rancho Palos Verdes, California); Ashraf Ibrahim (Irvine, California); Guanpingsheng Luo (Torrance, California) |
ABSTRACT | The present invention provides vaccine compositions comprising OmpA, or antigenic fragments thereof, and related methods of active immunization against A. baumannii infection. The invention also provides antibodies and antigen-binding parts thereof that specifically bind to OmpA, and related methods of passive immunization against A. baumannii infection. The compositions and methods of the invention are useful for preventing or treating A. baumannii infections, including those caused by strains resistant to carbapenems and all other antibiotics except colistin or tigecycline, also referred to as extreme drug resistant (XDR) A. baumannii infections, and those resistant to every FDA approved antibiotic, also referred to as pan-drug resistant (PDR) A. baumannii infections. |
FILED | Friday, May 11, 2012 |
APPL NO | 13/470177 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747860 | Rosenberger et al. |
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APPLICANT(S) | Carrie M. Rosenberger (San Francisco, California); Alan A. Aderem (Seattle, Washington) |
ASSIGNEE(S) | Institute for Systems Biology (Seattle, Washington) |
INVENTOR(S) | Carrie M. Rosenberger (San Francisco, California); Alan A. Aderem (Seattle, Washington) |
ABSTRACT | The invention is directed to an improved method to manufacture virus for use in vaccine by culturing infected cells that have been modified to overexpress miR-144. The invention is also directed to manipulating the activity or level of miR-144 in subjects in order to modulate the antiviral and immune response systems. |
FILED | Thursday, July 05, 2012 |
APPL NO | 13/542581 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/204.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747863 | Robbins et al. |
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APPLICANT(S) | John B. Robbins (New York, New York); Rachel Schneerson (Bethesda, Maryland); Joanna Kubler-Kielb (Bethesda, Maryland); Christopher P. Mocca (Columbia, Maryland); Evguenii Vinogradov (Ottawa, Canada) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); National Research Council of Canada (Ottawa, Canada) |
INVENTOR(S) | John B. Robbins (New York, New York); Rachel Schneerson (Bethesda, Maryland); Joanna Kubler-Kielb (Bethesda, Maryland); Christopher P. Mocca (Columbia, Maryland); Evguenii Vinogradov (Ottawa, Canada) |
ABSTRACT | Disclosed are immunogenic conjugates and therapeutic compositions that include such immunogenic conjugates. Also disclosed are methods of treating and/or inhibiting an Shigella sonnei infection. The disclosed immunogenic conjugates have the general structure: Pr—Sr—O—N═C-Kdo-OS wherein Pr is a carrier protein, Sr is an optional spacer moiety, Kdo is an 3-deoxy-D-manno-octulosonic acid or a derivative thereof, and OS is an oligosaccharide or polysaccharide obtained from S. sonnei. In specific examples, the immunogenic conjugates include the core oligosaccharide obtained from S. sonnei having the structure: wherein R is between 1 and 10 disaccharide repeat units. In specific examples, the disaccharide repeat unit included in the immunogenic conjugate has the structure: α-L-AltNAcA-3-β-FucNAc4N-4-. |
FILED | Friday, August 14, 2009 |
APPL NO | 13/059051 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/02 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 47/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747869 | Irvine et al. |
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FUNDED BY |
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APPLICANT(S) | Darrell J. Irvine (Arlington, Massachusetts); Jaehyun Moon (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Darrell J. Irvine (Arlington, Massachusetts); Jaehyun Moon (Cambridge, Massachusetts) |
ABSTRACT | The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents. |
FILED | Saturday, March 19, 2011 |
APPL NO | 13/052067 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1273 (20130101) A61K 2039/55572 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747870 | Gupta et al. |
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APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Kavita Gupta (Salt Lake City, Utah); Meredith R. Clark (Bethesda, Maryland); Patrick F. Kiser (Chicago, Illinois); Julie I. Jay (Salt Lake City, Utah) |
ABSTRACT | Described herein are polymeric compositions that comprise at least one polymer residue and at least one crosslinking moiety, wherein the polymer residue is crosslinked by the crosslinking moiety and wherein the crosslinking moiety is formed from a reaction between a boronic acid moiety and a hydroxamic acid moiety. Also, described are methods of making and using such polymeric compositions. |
FILED | Wednesday, January 16, 2013 |
APPL NO | 13/742877 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747905 | Yoon et al. |
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APPLICANT(S) | Young-Sup Yoon (Atlanta, Georgia); Hyun-Jai Cho (Seoul, South Korea) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Young-Sup Yoon (Atlanta, Georgia); Hyun-Jai Cho (Seoul, South Korea) |
ABSTRACT | As described below, the present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells. |
FILED | Monday, October 29, 2007 |
APPL NO | 12/447180 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/577 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747907 | Rzigalinski et al. |
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APPLICANT(S) | Beverly A. Rzigalinski (Radford, Virginia); Ariane M. Clark (Bradenton, Florida) |
ASSIGNEE(S) | |
INVENTOR(S) | Beverly A. Rzigalinski (Radford, Virginia); Ariane M. Clark (Bradenton, Florida) |
ABSTRACT | The present invention provides cerium oxide nanoparticles for use both in therapeutic compositions in vivo and in research in vitro. The cerium oxide nanoparticles are of known range of sizes having biological properties that are reproducible and beneficial. Pharmaceutical and other compositions are provided, as are methods of treatment. |
FILED | Monday, July 02, 2012 |
APPL NO | 13/539564 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/617 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747924 | Pasinetti et al. |
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FUNDED BY |
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APPLICANT(S) | Giulio Maria Pasinetti (New York, New York); Lap Ho (New York, New York); Jun Wang (Flushing, New York) |
ASSIGNEE(S) | Icahn School of Medicine At Mount Sinai (New York, New York) |
INVENTOR(S) | Giulio Maria Pasinetti (New York, New York); Lap Ho (New York, New York); Jun Wang (Flushing, New York) |
ABSTRACT | The present invention provide a method for the prevention and treatment of a neurodegenerative disease including Alzheimer's Disease, Huntington's Disease, and Parkinson's Disease, using a grape seed extract or one or more compounds derived therefrom. In particular, the present invention provides a method to treat a patient diagnosed with, or at the risk of developing, a neurodegenerative disease by administering a pharmaceutical composition comprising a grape seed extract or one or more compounds derived therefrom to the patient in a therapeutic amount to reduce the accumulation, aggregation or deposition of amyloid beta or its oligomers, and/or to reduce the misfolding, accumulation and/or aggregation of tau proteins or other proteins. |
FILED | Tuesday, November 09, 2010 |
APPL NO | 12/942785 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748085 | Pai et al. |
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APPLICANT(S) | Jeng-Hao Pai (Chapel Hill, North Carolina); Yuli Wang (Cary, North Carolina); Christopher E. Sims (Chapel Hill, North Carolina); Mark Bachman (Irvine, California); Nancy Allbritton (Chapel Hill, North Carolina); Guann-Pyng Li (Irvine, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jeng-Hao Pai (Chapel Hill, North Carolina); Yuli Wang (Cary, North Carolina); Christopher E. Sims (Chapel Hill, North Carolina); Mark Bachman (Irvine, California); Nancy Allbritton (Chapel Hill, North Carolina); Guann-Pyng Li (Irvine, California) |
ABSTRACT | Systems and methods directed to the use 1002F to build microdevices and biomedical devices. Through the addition of a photosensitizing agent, Epon epoxy resin 1002F can be linked in the presence of UV light, making it useful as a photoresist or as a micropatternable structural material. One embodiment comprises combining 1002F monomer resin with a solvent and a photoinitiator, placing the monomer solution on a surface, exposing the monomer solution to UV light through a mask to initiate linking, and stripping the unlinked polymer away. In another embodiment, 3-D structures are built using two or more layers of sensitized monomer films, each having different sensitivity to light, and the use of a mask containing opaque and semi-opaque regions. |
FILED | Friday, July 25, 2008 |
APPL NO | 12/670349 |
ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/322 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748089 | Kariko et al. |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Katalin Kariko (Rydal, Pennsylvania); Drew Weissman (Wynnewood, Pennsylvania) |
ABSTRACT | This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/839155 |
ART UNIT | 1674 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748091 | Timp et al. |
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APPLICANT(S) | Gregory Timp (South Bend, Indiana); Winston Timp (Baltimore, Maryland); Utkur Mirsaidov (Urbana, Illinois); Aleksei Aksimentiev (Urbana, Illinois); Jeffrey Comer (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The John Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Gregory Timp (South Bend, Indiana); Winston Timp (Baltimore, Maryland); Utkur Mirsaidov (Urbana, Illinois); Aleksei Aksimentiev (Urbana, Illinois); Jeffrey Comer (Urbana, Illinois) |
ABSTRACT | Methods of trapping a deformed portion of a double-stranded polynucleotide in a membrane nanopassage are provided. In an aspect, the membrane has a nanopassage that defines a confine region, wherein the membrane separates a first fluid compartment from a second fluid compartment, and the nanopassage is in fluid communication with the first and second compartments. A polynucleotide is provided to the first fluid compartment and optionally a threshold voltage for the membrane and the polynucleotide is determined. A driving voltage across the membrane that is greater than the threshold voltage is applied to force a portion of the polynucleotide sequence into the nanopassage confine region, and decreased to a holding voltage bias to trap the polynucleotide portion in the nanopassage confine region. In particular, at least one nucleotide base-pair is fixably positioned in the nanopassage confine volume. In further embodiments, any of the trapping methods are used to characterize or sequence double stranded DNA. |
FILED | Friday, December 17, 2010 |
APPL NO | 12/971240 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4146 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748096 | Ranum et al. |
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APPLICANT(S) | Laura P. W. Ranum (St. Paul, Minnesota); Michael D. Koob (Roseville, Minnesota); Kellie A. Benzow (Plymouth, Minnesota); Melinda L. Moseley-Alldredge (St. Paul, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Laura P. W. Ranum (St. Paul, Minnesota); Michael D. Koob (Roseville, Minnesota); Kellie A. Benzow (Plymouth, Minnesota); Melinda L. Moseley-Alldredge (St. Paul, Minnesota) |
ABSTRACT | The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided. |
FILED | Monday, August 20, 2012 |
APPL NO | 13/589266 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748098 | Hernando et al. |
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APPLICANT(S) | Eva Hernando (New York, New York); Miguel Segura (New York, New York); Douglas Hanniford (New York, New York); Silvia Menendez (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Eva Hernando (New York, New York); Miguel Segura (New York, New York); Douglas Hanniford (New York, New York); Silvia Menendez (New York, New York) |
ABSTRACT | Described herein are compositions and methods for the diagnosis, prognosis, prevention and treatment of melanoma or melanoma associated symptoms. The compositions are microRNA molecules associated with melanoma, as well as various nucleic acid molecules relating thereto or derived therefrom. |
FILED | Wednesday, August 08, 2012 |
APPL NO | 13/569845 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748106 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | Bal Ram Singh (N. Dartmouth, Massachusetts); Yu Zhou (New Bedford, Massachusetts) |
ASSIGNEE(S) | Bal Ram Singh (North Dartmouth, Massachusetts) |
INVENTOR(S) | Bal Ram Singh (N. Dartmouth, Massachusetts); Yu Zhou (New Bedford, Massachusetts) |
ABSTRACT | This application is based, inter alia, on the discovery of a binding interaction between the Hn-33 hemagglutinin polypeptide of the type A Clostridium botulinum neurotoxin complex and synaptosomal proteins, including synaptotagmin II (Syt II). Methods of screening for compounds that modulate, e.g., increase or decrease, this interaction are provided. Also provided are compositions and methods for targeting compounds to neuronal and cancer cells by coupling the compounds to Hn-33 or biologically active Hn-33 variants. |
FILED | Tuesday, April 18, 2006 |
APPL NO | 11/911889 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748113 | Matsui et al. |
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APPLICANT(S) | William Matsui (Baltimore, Maryland); Richard J. Jones (Baltimore, Maryland); Carol A. Huff (Ellicott City, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | William Matsui (Baltimore, Maryland); Richard J. Jones (Baltimore, Maryland); Carol A. Huff (Ellicott City, Maryland) |
ABSTRACT | Provided herein are compositions, methods, and kits useful for detecting whether a subject has or is likely to develop a cancer and for monitoring, staging and examining a cancer patient. Also provide herein are methods for screening compounds. |
FILED | Wednesday, November 12, 2008 |
APPL NO | 12/743180 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748114 | Staudt et al. |
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FUNDED BY |
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APPLICANT(S) | Louis M. Staudt (Silver Spring, Maryland); Andreas Rosenwald (Bethesda, Maryland); Wyndham Wilson (Washington, District of Columbia); Todd S. Barry (Seattle, Washington); Adrian Wiestner (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Louis M. Staudt (Silver Spring, Maryland); Andreas Rosenwald (Bethesda, Maryland); Wyndham Wilson (Washington, District of Columbia); Todd S. Barry (Seattle, Washington); Adrian Wiestner (Bethesda, Maryland) |
ABSTRACT | It has been surprisingly found that ZAP-70 expression, both at the protein and mRNA levels, is indicative of clinical subgroups of CLL/SLL patients. In particular, high ZAP-70 expression is indicative of Ig-unmutated CLL/SLL. Methods are provided for discriminating between clinical subgroups of CLL/SLL, by determining whether subjects overexpress ZAP-70 mRNA or protein. |
FILED | Tuesday, June 07, 2011 |
APPL NO | 13/155198 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748116 | Lee |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women s Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Richard T. Lee (Weston, Massachusetts) |
ABSTRACT | This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure. |
FILED | Thursday, March 07, 2013 |
APPL NO | 13/788276 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
08748119 — Methods for determining calcineurin activity, and uses in predicting therapeutic outcomes
US 08748119 | Gooch et al. |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Jennifer L. Gooch (Lilburn, Georgia); Brian R. Roberts (Sandy Springs, Georgia); Jan Pohl (Tucker, Georgia) |
ABSTRACT | One aspect of the present disclosure encompasses methods for determining a protein kinase or phosphatase activity in a biological sample, comprising: contacting in a reaction mix a first test sample and a fluorescently-labeled peptide substrate capable of being modified by a protein phosphatase or a protein kinase, contacting the reaction mix with a TiO2 matrix, thereby partitioning fluorescently-labeled phosphorylated peptide from fluorescently-labeled dephosphorylated peptide; and determining the fluorescence of the fluorescently-labeled dephosphorylated peptide, thereby determining a protein kinase or phosphatase activity. |
FILED | Thursday, December 06, 2012 |
APPL NO | 13/706750 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/21 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748121 | Blair et al. |
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FUNDED BY |
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APPLICANT(S) | Ian Blair (Wynnewood, Pennsylvania); Clementina Mesaros (Philadelphia, Pennsylvania); Wenying Jian (Princeton, New Jersey); Seon Hwa Lee (Aoba-ku, Japan); Tomoyuki Oe (Aoba-ku, Japan) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Ian Blair (Wynnewood, Pennsylvania); Clementina Mesaros (Philadelphia, Pennsylvania); Wenying Jian (Princeton, New Jersey); Seon Hwa Lee (Aoba-ku, Japan); Tomoyuki Oe (Aoba-ku, Japan) |
ABSTRACT | The invention relates to biomarkers of oxidative stress and their use. Specifically, the invention relates to thiadiazabicyclo-4-oxo-2(E)-nonenal-Glutathione adduct as a biomarker of oxidative stress and its diagnostic use. |
FILED | Tuesday, October 23, 2007 |
APPL NO | 11/976316 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/29 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748165 | Vangbo et al. |
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FUNDED BY |
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APPLICANT(S) | Mattias Vangbo (Fremont, California); William D. Nielsen (San Jose, California); Iuliu I. Blaga (Fremont, California); Michael Van Nguyen (San Diego, California); Steven B. Jovanovich (Livermore, California) |
ASSIGNEE(S) | IntegenX Inc. (Pleasanton, California) |
INVENTOR(S) | Mattias Vangbo (Fremont, California); William D. Nielsen (San Jose, California); Iuliu I. Blaga (Fremont, California); Michael Van Nguyen (San Diego, California); Steven B. Jovanovich (Livermore, California) |
ABSTRACT | This invention provides a method for generating short tandem repeat (STR) profiles on each of a plurality of samples comprising, for each sample: a) isolating DNA from the sample; b) amplifying STR markers in the isolated DNA and c) analyzing the amplification product by electrophoresis. |
FILED | Tuesday, August 21, 2012 |
APPL NO | 13/590965 |
ART UNIT | 1775 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748168 | Williams et al. |
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FUNDED BY |
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APPLICANT(S) | James A. Williams (Lincoln, Nebraska); Clague P. Hodgson (Omaha, Nebraska) |
ASSIGNEE(S) | Nature Technology Corp. (Lincoln, Nebraska) |
INVENTOR(S) | James A. Williams (Lincoln, Nebraska); Clague P. Hodgson (Omaha, Nebraska) |
ABSTRACT | A general method and strains of bacteria are described, by means of which it is possible to dramatically purify plasmid DNA with respect to genomic DNA, and RNA. In one preferred embodiment, lysis and nuclease removal of host nucleic acids is an integral component of the fermentation/harvest process, and as such, achieves increased yield and purity with simplified downstream purification and reduced waste streams, thus reducing production costs. |
FILED | Monday, August 15, 2005 |
APPL NO | 11/573756 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748170 | Finn et al. |
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FUNDED BY |
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APPLICANT(S) | Olivera J. Finn (Pittsburgh, Pennsylvania); Laura A. Vella-Geynisman (Chicago, Illinois) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Olivera J. Finn (Pittsburgh, Pennsylvania); Laura A. Vella-Geynisman (Chicago, Illinois) |
ABSTRACT | In one embodiment, the invention provides a composition comprising one or more polypeptide(s), each of said polypeptide(s) comprising a sequence selected from the group consisting of KFRLLQETMYMTVSI (SEQ ID NO: 1), LQETMYMTVSIIDRF (SEQ ID NO: 2), and MYMTVSIIDRFM (SEQ ID NO: 3), or a combination of two or three such polypeptides, wherein each of said polypeptide(s) consist(s) of at most 24 amino acid residues, the composition also comprising a carrier. In another embodiment, the invention provides a composition comprising one or more bacterial or viral vectors comprising one or more nucleic acid molecule(s) encoding one or more polypeptide(s), each of said polypeptide(s) having a sequence selected from the group consisting of KFRLLQETMYMTVSI (SEQ ID NO: 1), LQETMYMTVSIIDRF (SEQ ID NO: 2), and MYMTVSIIDRFM (SEQ ID NO: 3), wherein each of said polypeptide(s) consist(s) of at most 24 amino acid residues. |
FILED | Monday, July 27, 2009 |
APPL NO | 13/055907 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748171 | Keller et al. |
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FUNDED BY |
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APPLICANT(S) | Gordon M Keller (Toronto, Canada); Valerie Kouskoff (Manchester, United Kingdom); Atsushi Kubo (Nara, Japan); Hans Joerg Fehling (Ulm, Germany) |
ASSIGNEE(S) | Mount Sinai School of Medicine (New York, New York) |
INVENTOR(S) | Gordon M Keller (Toronto, Canada); Valerie Kouskoff (Manchester, United Kingdom); Atsushi Kubo (Nara, Japan); Hans Joerg Fehling (Ulm, Germany) |
ABSTRACT | The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy. |
FILED | Wednesday, July 14, 2010 |
APPL NO | 12/836275 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748173 | Kearney |
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FUNDED BY |
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APPLICANT(S) | John F. Kearney (Birmingham, Alabama) |
ASSIGNEE(S) | UAB Research Foundation (Birmingham, Alabama) |
INVENTOR(S) | John F. Kearney (Birmingham, Alabama) |
ABSTRACT | The present invention provides monoclonal antibodies which are highly specific for Bacillus spores. Also provided are peptides derived from those monoclonal antibodies. Both the antibodies and peptides are highly specific and can discriminate between spores of potentially lethal organisms such as Bacillus anthracis and other harmless but closely related bacilli and provide a very powerful tool in the construction of detection instruments as counter measures. |
FILED | Friday, November 17, 2006 |
APPL NO | 11/601133 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/340 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748192 | Tian et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Yanqing Tian (Chandler, Arizona); Weiwen Zhang (Chandler, Arizona); Deirdre Meldrum (Phoenix, Arizona); Hongguang Lu (Harbin, China PRC); Yuguang Jin (Gilbert, Arizona); Mark Holl (Tempe, Arizona) |
ABSTRACT | The present invention relates to an optical fluorescence dual sensor comprising a probe for sensing pH, a probe for sensing oxygen, an intra-reference probe and a matrix. The present invention also relates to methods of preparing an optical fluorescence dual sensor and methods of using them. |
FILED | Wednesday, October 24, 2012 |
APPL NO | 13/659821 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/136 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748338 | Luthy et al. |
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FUNDED BY |
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APPLICANT(S) | Richard G. Luthy (Stanford, California); Eun Ah Kim (Menlo Park, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Richard G. Luthy (Stanford, California); Eun Ah Kim (Menlo Park, California) |
ABSTRACT | A toxin immobilization particle and method of fabrication is provided that includes a polysulfide-rubber polymer coated activated carbon particle that provides enhanced toxin adsorption. A porous activated carbon particle have a size range up to 2 mm is used. The polysulfide-rubber polymer coated activated carbon particle includes a polymer-dose range of up to 1.64 grams of sulfur per gram of activated carbon particles, where the toxins can include mercury, PCBs, chlorinated pesticides or polycyclic aromatic hydrocarbons. The method of forming the toxin immobilization particle includes condensing a polymer in a sulfide mixture to form a polysulfide-rubber polymer compound and coating an activated carbon particle with the polysulfide-rubber polymer. The levels of sulfur loading in the toxin immobilization particles are controlled by the polymer dose during the coating process, where the polysulfide polymer coated activated carbon particle provides enhanced toxin adsorption. |
FILED | Friday, October 21, 2011 |
APPL NO | 13/317555 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/402 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748354 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Howard Yuan-Hao Chang (Stanford, California); Ci Chu (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Howard Yuan-Hao Chang (Stanford, California); Ci Chu (Stanford, California) |
ABSTRACT | A method of sample analysis is provided. In certain cases, the method comprises: a) cross-linking the contents of a cell using a heat stable crosslinking agent to produce cross-linked ribonucleotide complexes; b) fragmenting the cross-linked ribonucleotide complexes to produce complexes comprising protein, RNA fragments and, optionally, genomic DNA fragments; c) contacting the complexes with a plurality of non-overlapping oligonucleotides comprise an affinity tag and that are complementary to a specific target RNA of the cell under high stringency conditions that include high temperature; d) isolating complexes that contain the oligonucleotides using the affinity tag to produce isolated complexes; e) enzymatically releasing the protein, RNA fragments and/or the genomic DNA fragments from the isolated complexes to produce a released component, without reversing the crosslinking; and f) analyzing the released component. |
FILED | Tuesday, August 07, 2012 |
APPL NO | 13/569005 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/9 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748369 | Epperly et al. |
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FUNDED BY |
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APPLICANT(S) | Michael W. Epperly (Pittsburgh, Pennsylvania); Abhay Sudhir Gokhale (Galena, Ohio); Joel S. Greenberger (Sawickley, Pennsylvania); Peter Wipf (Pittsburgh, Pennsylvania); Julianne Glowacki (Jamaica Plain, Massachusetts) |
ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Michael W. Epperly (Pittsburgh, Pennsylvania); Abhay Sudhir Gokhale (Galena, Ohio); Joel S. Greenberger (Sawickley, Pennsylvania); Peter Wipf (Pittsburgh, Pennsylvania); Julianne Glowacki (Jamaica Plain, Massachusetts) |
ABSTRACT | Provided herein are compositions and related methods useful for accelerating bone healing and growth. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. |
FILED | Friday, June 04, 2010 |
APPL NO | 13/320999 |
ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748372 | Luban et al. |
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FUNDED BY |
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APPLICANT(S) | Jeremy Luban (New York, New York); David Sayah (San Francisco, California) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Jeremy Luban (New York, New York); David Sayah (San Francisco, California) |
ABSTRACT | The invention provides an isolated nucleic acid encoding a TRIM-cyclophilin A fusion sequence encoding a TRIMcyp fusion protein which is active as an anti-viral agent, and in particular an anti-HIV-1 agent. The invention provides for a nucleic acid encoding a polypeptide having both TRIM activity and cyclophilin activity. The invention provides for an isolated polynucleotide encoding a TRIM-cyclophilin fusion protein, or variants thereof retaining the TRIM and cyclophilin activities. The invention provides for compositions thereof, antibodies that specifically bind thereto, and vectors and host cells comprising the nucleic acid or polypeptide. In addition, the invention provides for methods for treating or preventing viral infection, or reducing viral load in a subject comprising administering the nucleic acid, polypeptide, vector, or composition to the subject in an amount effective to treat or prevent the viral infection. |
FILED | Tuesday, December 20, 2011 |
APPL NO | 13/331363 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/3.800 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748373 | Chai et al. |
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FUNDED BY |
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APPLICANT(S) | Ning Chai (Philadelphia, Pennsylvania); John M. Taylor (Cheltenham, Pennsylvania) |
ASSIGNEE(S) | Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
INVENTOR(S) | Ning Chai (Philadelphia, Pennsylvania); John M. Taylor (Cheltenham, Pennsylvania) |
ABSTRACT | A polypeptide comprising a preS1 region of hepatitis B virus (HBV), or a fragment thereof, and/or the preS2 region of HBV or a fragment thereof, and methods of use to inhibit virus infection are disclosed. A lentivirus comprising hepatitis B virus (HBV) envelope proteins, or a fragment thereof, and/or the L envelope protein of HBV and/or the M envelope protein of HBV or a fragment thereof, and/or the S envelope protein of HBV or a fragment thereof, and methods of use of this lentivirus HBV pseudovirus as a gene therapy to target hepatocytes for the administration of therapeutic agents are also disclosed. |
FILED | Wednesday, February 20, 2008 |
APPL NO | 12/526759 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/4.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748381 | Polk et al. |
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FUNDED BY |
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APPLICANT(S) | D. Brent Polk (Los Angeles, California); Fang Yan (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | D. Brent Polk (Los Angeles, California); Fang Yan (Nashville, Tennessee) |
ABSTRACT | The present invention provides therapeutic and prophylactic compositions for use in treating and preventing disorders involving epithelial cell apoptosis, such as gastrointestinal disorders (e.g., inflammatory bowel disease, Crohn's disease or ulcerative colitis) in a subject, such as a human patient. |
FILED | Wednesday, April 28, 2010 |
APPL NO | 13/318010 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/16.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748385 | O'Shea et al. |
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FUNDED BY |
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APPLICANT(S) | Kathy Sue O'Shea (Ann Arbor, Michigan); Maria Morell (Granada, Spain) |
ASSIGNEE(S) | Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Kathy Sue O'Shea (Ann Arbor, Michigan); Maria Morell (Granada, Spain) |
ABSTRACT | This disclosure describes a novel population of cerebellum-derived neural stem cells that can be isolated from the adult brain, expanded, and differentiated into neurons, astrocytes and oligodendrocytes. This disclosure also describes compositions and methods for producing oligodendrocytes. Oligodendrocytes can be produced in vitro (e.g., in culture) or in vivo (e.g., for therapy or in a non-human transgenic animal) using the compositions and methods described herein. |
FILED | Tuesday, June 08, 2010 |
APPL NO | 13/375269 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748386 | Sigurdsson |
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FUNDED BY |
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APPLICANT(S) | Einar M. Sigurdsson (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Einar M. Sigurdsson (New York, New York) |
ABSTRACT | The present invention relates to methods and compositions for treating, preventing, and diagnosing Alzheimer's Disease or other tauopathies in a subject by administering an immunogenic tau peptide or an antibody recognizing the immunogenic tau epitope under conditions effective to treat, prevent, or diagnose Alzheimer's Disease or other tauopathies. Also disclosed are methods of promoting clearance of aggregates from the brain of the subject and of slowing progression of tau-pathology related behavioral phenotype in a subject. |
FILED | Thursday, June 10, 2010 |
APPL NO | 12/813297 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.800 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748390 | Schlom et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey Schlom (Potomac, Maryland); Kwong-Yok Tsang (Bethesda, Maryland); Ira Pastan (Potomac, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey Schlom (Potomac, Maryland); Kwong-Yok Tsang (Bethesda, Maryland); Ira Pastan (Potomac, Maryland) |
ABSTRACT | The invention provides a peptide comprising a human cytolytic T lymphocyte (CTL) epitope from the human tumor-associated antigen (TAA) New Gene Expressed in Prostate (NGEP), which can be used in vaccine prevention or therapy of prostate cancer, as well as a nucleic acid encoding the peptide, a vector comprising the nucleic acid, a cell comprising the peptide, nucleic acid, or vector, and compositions thereof. |
FILED | Monday, April 19, 2010 |
APPL NO | 13/265490 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748392 | Cox, III |
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FUNDED BY |
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APPLICANT(S) | George N. Cox, III (Louisville, Colorado) |
ASSIGNEE(S) | Bolder BioTechnology Inc. (Boulder, Colorado) |
INVENTOR(S) | George N. Cox, III (Louisville, Colorado) |
ABSTRACT | Disclosed are cysteine variants of interleukin-11 (IL-11) and methods of making and using such proteins in therapeutic applications. |
FILED | Thursday, February 02, 2012 |
APPL NO | 13/365158 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748393 | Mochly-Rosen et al. |
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FUNDED BY |
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APPLICANT(S) | Daria Mochly-Rosen (Menlo Park, California); Xin Qi (Beachwood, Ohio); Nir Qvit (Menlo Park, California) |
ASSIGNEE(S) | The Board of Trustees of The Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Daria Mochly-Rosen (Menlo Park, California); Xin Qi (Beachwood, Ohio); Nir Qvit (Menlo Park, California) |
ABSTRACT | The present disclosure provides peptides and constructs that inhibit mitochondrial fission, and compositions comprising the peptides or constructs. The present disclosure provides methods of reducing abnormal mitochondrial fission in a cell. Also provided are methods for designing and validating mitochondrial fission inhibitor constructs and peptides, including but not limited to, evaluating the effects of the constructs and peptides on dynamin 1-like protein (Drp1) guanosine triphosphate phosphatase (GTPase) activity, binding of Drp1 to mitochondrial fission 1 protein (Fis1), reduction of mitochondrial damage, reduction in cell death, inhibition of mitochondrial fragmentation in a cell under pathological conditions, and reduced loss of neurites in primary dopaminergic neurons in a Parkinsonism cell culture. |
FILED | Monday, May 14, 2012 |
APPL NO | 13/471221 |
ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Original (OR) Class A61K 51/08 (20130101) Peptides C07K 14/00 (20130101) C07K 2319/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748403 | Kurt-Jones et al. |
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FUNDED BY |
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APPLICANT(S) | Evelyn A. Kurt-Jones (Belmont, Massachusetts); Robert W. Finberg (Sudbury, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Evelyn A. Kurt-Jones (Belmont, Massachusetts); Robert W. Finberg (Sudbury, Massachusetts) |
ABSTRACT | Toll-like receptor 2 (TLR2) has been found to mediate certain effects of HSV infection, particularly in neonates. Compounds that decrease TLR2 expression or activity are useful for ameliorating such deleterious effects. |
FILED | Friday, January 21, 2005 |
APPL NO | 11/041065 |
ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748404 | Steinman et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Steinman (Palo Alto, California); Pedro Ruiz (Menlo Park, California); Hideki Garren (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Lawrence Steinman (Palo Alto, California); Pedro Ruiz (Menlo Park, California); Hideki Garren (Palo Alto, California) |
ABSTRACT | A pro-inflammatory T cell response is specifically suppressed by the injection into a recipient of DNA encoding an autoantigen associated with autoimmune disease. The recipient may be further treating by co-vaccination with a DNA encoding a Th2 cytokine, particularly encoding IL4. In response to the vaccination, the proliferation of autoantigen-reactive T cells and the secretion of Th1 cytokines, including IL-2, IFN-γ and IL-15, are reduced. |
FILED | Monday, April 05, 2010 |
APPL NO | 12/754555 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748405 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Hua Yu (Glendora, California); Marcin Kortylewski (Monrovia, California); Richard Jove (Glendora, California); Piotr Marek Swiderski (San Dimas, California); John J. Rossi (Alta Loma, California) |
ASSIGNEE(S) | City of Hope (Duarte, California) |
INVENTOR(S) | Hua Yu (Glendora, California); Marcin Kortylewski (Monrovia, California); Richard Jove (Glendora, California); Piotr Marek Swiderski (San Dimas, California); John J. Rossi (Alta Loma, California) |
ABSTRACT | The present invention relates to methods and compositions for the treatment of diseases, including cancer, infectious diseases and autoimmune diseases. The present invention also relates to methods and compositions for improving immune function. More particularly, the present invention relates to multifunctional molecules that are capable of being delivered to cells of interest for the treatment of diseases and for the improvement in immune function. |
FILED | Friday, September 09, 2011 |
APPL NO | 13/229146 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748445 | Chung et al. |
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FUNDED BY |
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APPLICANT(S) | W. Joon Chung (Birmingham, Alabama); Harald Sontheimer (Birmingham, Alabama) |
ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
INVENTOR(S) | W. Joon Chung (Birmingham, Alabama); Harald Sontheimer (Birmingham, Alabama) |
ABSTRACT | The present disclosure provides for method of treatment and/or prevention of disease states that require cystine for maintenance or progression of the disease state. In addition, methods for screening and identifying novel therapeutic agents useful in the treatment of such disease states are described. In one embodiment, the disease state is a cancer, such as, but not limited to, glioma. In this embodiment, methods for the treatment and prevention of glioma by inhibiting cystine uptake or decreasing intracellular cystine concentrations are provided. The present disclosure teaches that glioma cells are dependent on system Xc for cystine uptake. Pharmacological inhibition of system Xc causes a rapid depletion of intracellular glutathione, resulting in decreased cell growth. In contrast, non-malignant astrocytes and cortical neurons remain viable in the presence of Xc inhibitors and continue to take up cystine via alternate amino acid transporters. |
FILED | Thursday, October 27, 2005 |
APPL NO | 11/791588 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/275 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748451 | Kozikowski et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of The University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Alan Kozikowski (Chicago, Illinois); Kyle Vincent Butler (Stanford, California); Jay Hans Kalin (Chicago, Illinois) |
ABSTRACT | Histone deacetylases inhibitors (HDACIs) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease, traumatic brain injury, stroke, malaria, an autoimmune disease, autism, and inflammation, also are disclosed. |
FILED | Monday, April 22, 2013 |
APPL NO | 13/867438 |
ART UNIT | 1676 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/292 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748464 | Verdin et al. |
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FUNDED BY |
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APPLICANT(S) | Eric M. Verdin (San Francisco, California); Melanie Ott (San Francisco, California); Hye-Sook Kwon (San Mateo, California); Hyungwook Lim (San Francisco, California) |
ASSIGNEE(S) | The J. David Gladstone Institutes (San Francisco, California) |
INVENTOR(S) | Eric M. Verdin (San Francisco, California); Melanie Ott (San Francisco, California); Hye-Sook Kwon (San Mateo, California); Hyungwook Lim (San Francisco, California) |
ABSTRACT | The present disclosure provides a method of increasing an immune response in an individual, the method involving administering to an individual in need thereof an inhibitor of SIRT1. The present disclosure provides a method of reducing an immune response, e.g., to treat chronic immune hyperactivity, the method generally involving administering to an individual in need thereof an activator of SIRT1. The present disclosure provides a method of modulating activation and differentiation of CD4+ T cells. |
FILED | Friday, July 16, 2010 |
APPL NO | 12/838247 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/366 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748469 | Mautino et al. |
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FUNDED BY |
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APPLICANT(S) | Mario R. Mautino (Ankeny, Iowa); Sanjeev Kumar (Ames, Iowa); Firoz Jaipuri (Ames, Iowa); Jesse Waldo (Ames, Iowa); Tanay Kesharwani (Lake Katrine, New York); Nicholas N. Vahanian (Polk City, Iowa); Charles J. Link (Clive, Iowa) |
ASSIGNEE(S) | NewLink Genetics Corporation (Ames, Iowa); Lankeanau Institute for Medical Research (Wynnewood, Pennsylvania) |
INVENTOR(S) | Mario R. Mautino (Ankeny, Iowa); Sanjeev Kumar (Ames, Iowa); Firoz Jaipuri (Ames, Iowa); Jesse Waldo (Ames, Iowa); Tanay Kesharwani (Lake Katrine, New York); Nicholas N. Vahanian (Polk City, Iowa); Charles J. Link (Clive, Iowa) |
ABSTRACT | Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R1, R4, and R5 are defined herein. Such compounds and compositions are useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine -2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease. |
FILED | Friday, April 24, 2009 |
APPL NO | 12/988391 |
ART UNIT | 1672 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/399 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748470 | Lengyel et al. |
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FUNDED BY |
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APPLICANT(S) | Ernst Lengyel (Chicago, Illinois); Kristin Nieman (Westchester, Illinois); Hilary Kenny (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Ernst Lengyel (Chicago, Illinois); Kristin Nieman (Westchester, Illinois); Hilary Kenny (Chicago, Illinois) |
ABSTRACT | The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins. |
FILED | Friday, March 16, 2012 |
APPL NO | 13/422712 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/406 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748473 | McKnight et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of the Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Steven L. McKnight (Dallas, Texas); Andrew A. Pieper (Iowa City, Iowa); Joseph M. Ready (Carrollton, Texas); Jef K. De Brabander (Flower Mound, Texas) |
ABSTRACT | This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death. |
FILED | Monday, January 14, 2013 |
APPL NO | 13/740876 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748480 | Smrcka et al. |
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FUNDED BY |
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APPLICANT(S) | University of Rochester (Rochester, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Alan V. Smrcka (Rochester, New York); Jose Font (Fairport, New York); Tabetha Bonacci (Kimball, Minnesota) |
ABSTRACT | The present invention relates to methods for identifying agents which bind to specific amino acid residues of the protein interaction site of G protein β protein subunit. Compounds identified in accordance with the assay of the invention and methods for using the compound for modulating at least one activity of a G protein are also provided. |
FILED | Friday, September 28, 2012 |
APPL NO | 13/630995 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/454 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748567 | Narasimhaswamy et al. |
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FUNDED BY |
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APPLICANT(S) | Manjunath Narasimhaswamy (El Paso, Texas); Premlata Shankar (El Paso, Texas); Priti Kumar (Hamden, Connecticut) |
ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
INVENTOR(S) | Manjunath Narasimhaswamy (El Paso, Texas); Premlata Shankar (El Paso, Texas); Priti Kumar (Hamden, Connecticut) |
ABSTRACT | The present invention provides compositions and methods useful for delivering agents to target cells or tissues, for example nerve cells and other cells in the central nervous system. The compositions and methods are useful for delivering agents across the blood-brain barrier. The present invention also provides methods of using the compositions provided by the present invention to deliver agents, for example therapeutic agents for the treatment of neurologically related disorders. |
FILED | Tuesday, May 22, 2007 |
APPL NO | 12/301847 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748568 | Goldfarb et al. |
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FUNDED BY |
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APPLICANT(S) | Mitchell Goldfarb (River Edge, New Jersey); Dover Katarzyna (Riverdale, New York) |
ASSIGNEE(S) | Research Foundation of The City University of New York (New York, New York) |
INVENTOR(S) | Mitchell Goldfarb (River Edge, New Jersey); Dover Katarzyna (Riverdale, New York) |
ABSTRACT | Isolated peptides are provided that are effective in inducing long-term inactivation of voltage-gated sodium channels (VGSCs) in mammalian cells. Such peptides are useful in reducing the action potentials of these excitable cells, for example, neurons, myocytes, and tonic muscle cells, in mammals in need thereof. |
FILED | Thursday, May 06, 2010 |
APPL NO | 13/319016 |
ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/47 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/861 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748569 | Stupp et al. |
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FUNDED BY |
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APPLICANT(S) | Samuel I. Stupp (Chicago, Illinois); Joshua E. Goldberger (Columbus, Ohio); Eric J. Berns (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Joshua E. Goldberger (Columbus, Ohio); Eric J. Berns (Chicago, Illinois) |
ABSTRACT | The present invention is directed to peptide amphiphile compounds, compositions and methods of use, wherein nanofiber bundling or epitope aggregation is inhibited. In certain embodiments, the peptide amphiphiles of the present invention have increased solubility and reduced nanofiber bundling. The molecules may be used in pharmaceutical applications, for example for in vivo administration to human patients, by increasing biological activity of the compositions toward neurite outgrowth and nerve regeneration. |
FILED | Monday, April 09, 2012 |
APPL NO | 13/442210 |
ART UNIT | 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5169 (20130101) A61K 38/00 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 2/00 (20130101) C07K 2319/735 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/795 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748572 | Nitto et al. |
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FUNDED BY |
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APPLICANT(S) | Takeaki Nitto (Saga, Japan); Kimberly D. Dyer (Reston, Virginia); Meggan Czapiga (Bethesda, Maryland); Helene F. Rosenberg (Bethesda, Maryland); Steven J. Siegel (Rockville, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Takeaki Nitto (Saga, Japan); Kimberly D. Dyer (Reston, Virginia); Meggan Czapiga (Bethesda, Maryland); Helene F. Rosenberg (Bethesda, Maryland); Steven J. Siegel (Rockville, Maryland) |
ABSTRACT | The present invention features isolated polypeptides that have bactericidal and angiogenic activities. The invention features isolated polypeptides comprising amino acid sequences of RNase A ribonucleases, fragments and variants thereof, pharmaceutical compositions, and methods for treatment of a subject. |
FILED | Friday, August 24, 2007 |
APPL NO | 12/438700 |
ART UNIT | 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/326 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748591 | Weaver et al. |
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FUNDED BY |
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APPLICANT(S) | Scott C. Weaver (Galveston, Texas); Ilya Frolov (Galveston, Texas) |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Scott C. Weaver (Galveston, Texas); Ilya Frolov (Galveston, Texas) |
ABSTRACT | The present invention discloses a chimeric alphavirus comprising a Sindbis virus cDNA fragment, an Eastern equine encephalitis virus cDNA fragment, a Western equine encephalitis virus cDNA fragment or a combination thereof. The present also discloses the use of this chimeric alphavirus as vaccines and in serological and diagnostic assays. |
FILED | Thursday, April 17, 2008 |
APPL NO | 12/148172 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/23.720 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748601 | Taunton et al. |
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FUNDED BY |
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APPLICANT(S) | Jack Taunton (San Francisco, California); Michael Cohen (San Francisco, California); Kevan Shokat (San Francisco, California); Chao Zhang (San Francisco, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jack Taunton (San Francisco, California); Michael Cohen (San Francisco, California); Kevan Shokat (San Francisco, California); Chao Zhang (San Francisco, California) |
ABSTRACT | Inhibition of protein kinases having one or more cysteine residues within the ATP binding site is effected by contacting the kinase, per se or in a cell or subject, with an inhibitory-effective amount of a compound having a heterocyclic core structure comprised of two or more fused rings containing at least one nitrogen ring atom, and an electrophilic substituent that is capable of reacting with a cysteine residue within the ATP binding site of a kinase. Preferred compounds include certain pyrrolopyrimidines and oxindoles having such an electrophilic substituent and optionally an aromatic or heteroaromatic substituent that is capable of interacting with a threonine or smaller residue located in the gatekeeper position of the kinase. Kinases lacking such cysteine residues may be engineered or modified so that they are capable of being inhibited by such compounds by replacing a valine or other amino acid residue within the ATP binding site by a cysteine residue. |
FILED | Tuesday, September 26, 2006 |
APPL NO | 12/088059 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748608 | Newman et al. |
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FUNDED BY |
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APPLICANT(S) | Amy Hauck Newman (Phoenix, Maryland); Peter Grundt (Duluth, Minnesota); George C. Cyriac (Severna Park, Maryland); Robert Luedtke (Fort Worth, Texas); Jianjing Cao (Ellicott City, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); The University of North Texas Health Science Center at Fort Worth (Fort Worth, Texas) |
INVENTOR(S) | Amy Hauck Newman (Phoenix, Maryland); Peter Grundt (Duluth, Minnesota); George C. Cyriac (Severna Park, Maryland); Robert Luedtke (Fort Worth, Texas); Jianjing Cao (Ellicott City, Maryland) |
ABSTRACT | Dopamine D3 receptor antagonists and partial agonists are known to modulate the reinforcing and drug-seeking effects induced by cocaine and other abused substances. By introducing functionality into the butylamide linking chain of the 4-phenylpiperazine class of ligands, improved D3 receptor affinity and selectivity, as well as water solubility, is achieved. A series of linking-chain derivatives are disclosed wherein functionality such as OH or OAc groups have been introduced into the linking chain. In general, these modifications are well tolerated at D3 receptors and achieve high selectivity over D2 and D4 receptors. |
FILED | Friday, June 15, 2007 |
APPL NO | 12/664668 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Organic compounds 544/360 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748618 | Bushweller et al. |
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FUNDED BY |
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APPLICANT(S) | John H. Bushweller (Charlottesville, Virginia); Jolanta Grembecka (Ann Arbor, Michigan); Anuradha Illendula (Charlottesville, Virginia); Lauren Dixon (Ann Arbor, Michigan) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | John H. Bushweller (Charlottesville, Virginia); Jolanta Grembecka (Ann Arbor, Michigan); Anuradha Illendula (Charlottesville, Virginia); Lauren Dixon (Ann Arbor, Michigan) |
ABSTRACT | This invention describes the development of targeted small molecule inhibitors of the inv(16) fusion, the causative agent in ˜12% of acute myeloid leukemia (AML). The inv(16) fusion results in expression of the CBFβ-SMMHC fusion protein in the blood cells of afflicted patients. The present invention provides compounds which inhibit the function of both CBFβ and the CBFβ-SMMHC fusion. These compounds block the growth of an inv(16) leukemia cell line as well as increase its apoptosis, while showing minimal effects against non inv(16) cell lines. As a mechanism to develop inhibitors with selectivity for the CBFβ-SMMHC fusion protein, the present invention further provides dimeric derivatives of these compounds which show both increased potency as well selectivity for CBFβ-SMMHC. These compounds show potent inhibition of an inv(16) leukemia cell line with minimal effects on non inv(16) cell lines. Analysis of the pharmacokinetics of the developed compounds has made it possible to improve the lifetime of the compound in the plasma of mice to a level commensurate with long-term treatment. |
FILED | Thursday, May 13, 2010 |
APPL NO | 13/320123 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/256 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748623 | Maeda et al. |
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FUNDED BY |
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APPLICANT(S) | Dean Y. Maeda (Seattle, Washington); John A. Zebala (Sammamish, Washington) |
ASSIGNEE(S) | Syntrix Biosystems, Inc. (Auburn, Washington) |
INVENTOR(S) | Dean Y. Maeda (Seattle, Washington); John A. Zebala (Sammamish, Washington) |
ABSTRACT | There is disclosed pyridine-and pyrimidinecarboxamide compounds useful as pharmaceutical agents, synthesis processes, and pharmaceutical compositions which include pyridine-and pyrimidinecarboxamides compounds. More specifically, there is disclosed a genus of CXCR2 inhibitor compounds that are useful for treating a variety of inflammatory and neoplastic disorders. |
FILED | Wednesday, February 17, 2010 |
APPL NO | 12/707647 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/297 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748632 | Cosford et al. |
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FUNDED BY |
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APPLICANT(S) | Nicholas D. P. Cosford (La Jolla, California); Dhanya Raveendra Panickar (La Jolla, California); Shyama Sidique (La Jolla, California); Svetlana Semenova (La Jolla, California); Athinia Markou (La Jolla, California) |
ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Nicholas D. P. Cosford (La Jolla, California); Dhanya Raveendra Panickar (La Jolla, California); Shyama Sidique (La Jolla, California); Svetlana Semenova (La Jolla, California); Athinia Markou (La Jolla, California) |
ABSTRACT | The disclosure provides compounds and compositions, and methods of using these compounds and compositions, as positive allosteric modulators of the metabotropic glutamate subtype 2 (mGlu2) receptor, and for treating CNS disorders associated with the mGlu2 receptor including schizophrenia, anxiety, addiction, e.g. cocaine addiction, nicotine addiction, and the like. |
FILED | Friday, March 18, 2011 |
APPL NO | 13/051798 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4035 (20130101) Heterocyclic Compounds C07D 209/46 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748933 | Bawendi et al. |
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FUNDED BY |
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APPLICANT(S) | Moungi G. Bawendi (Cambridge, Massachusetts); Sang-wook Kim (Brookline, Massachusetts); John P. Zimmer (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Moungi G. Bawendi (Cambridge, Massachusetts); Sang-wook Kim (Brookline, Massachusetts); John P. Zimmer (Cambridge, Massachusetts) |
ABSTRACT | Semiconductor nanocrystals including III-V semiconductors can include a core including III-V alloy. The nanocrystal can include an overcoating including a II-VI semiconductor. |
FILED | Monday, March 12, 2012 |
APPL NO | 13/417894 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750586 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Ruikang Wang (Portland, Oregon); Lin An (Portland, Oregon) |
ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Ruikang Wang (Portland, Oregon); Lin An (Portland, Oregon) |
ABSTRACT | Embodiments provide methods and systems for quantitative imaging of blood perfusion in living tissue. A method provides for obtaining an optical microangiography (OMAG) image of a sample, wherein the image has an OMAG background sample; digitally reconstructing a homogeneous ideal static background tissue; replacing the OMAG background sample with the digitally reconstructed homogeneous ideal static background tissue; correlating two or more neighboring A-lines with the digitally reconstructed homogeneous ideal static background tissue; and measuring a phase difference between the two or more neighboring A-lines to quantify blood perfusion in the sample. Methods using digital reconstruction to reduce random phase noise in phase-resolved Doppler OCT are also provided. |
FILED | Tuesday, May 04, 2010 |
APPL NO | 13/318737 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image analysis 382/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750642 | Corum et al. |
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FUNDED BY |
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APPLICANT(S) | Curtis A. Corum (Shoreview, Minnesota); Djaudat S. Idiyatullin (New Brighton, Minnesota); Steen Moeller (Golden Valley, Minnesota); Michael G. Garwood (Medina, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Curtis A. Corum (Shoreview, Minnesota); Djaudat S. Idiyatullin (New Brighton, Minnesota); Steen Moeller (Golden Valley, Minnesota); Michael G. Garwood (Medina, Minnesota) |
ABSTRACT | This document discloses, among other things, a method for removing a bullseye artifact from a radial image generated using magnetic resonance and using a swept frequency pulse. |
FILED | Friday, July 06, 2012 |
APPL NO | 13/543706 |
ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image analysis 382/275 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750652 | Butte et al. |
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FUNDED BY |
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APPLICANT(S) | Manish J. Butte (Stanford, California); John J. LeBlanc (North Andover, Massachusetts) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California); The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Manish J. Butte (Stanford, California); John J. LeBlanc (North Andover, Massachusetts) |
ABSTRACT | A microfluidic detection device is provided that includes a planar waveguide, or an ion-exchange planar waveguide, a microfluidic channel disposed on the planar waveguide, a light source, such as a laser, LED or incandescent light, directed through the planar waveguide, a labeled cell disposed in the microfluidic channel, where the labeled cell lies in an evanescent field extending from the planar waveguide, and a light detector disposed to receive light from the light source through the planar waveguide. The evanescent field interacts with the labeled cell, where the light through the planar waveguide is altered according to a presence of the labeled cell in the microfluidic channel. |
FILED | Wednesday, October 12, 2011 |
APPL NO | 13/317180 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08752006 | Tolle |
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FUNDED BY |
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APPLICANT(S) | Gilman Tolle (San Francisco, California) |
ASSIGNEE(S) | Cisco Technology, Inc. (San Jose, California) |
INVENTOR(S) | Gilman Tolle (San Francisco, California) |
ABSTRACT | A system and method accepts source code for one or more procedures and, for those procedures flagged as being remotely callable, generates communication code and a description that allows the code to be remotely callable via a server using a variety of formats, such as conventional web services formats. |
FILED | Monday, July 02, 2007 |
APPL NO | 11/824956 |
ART UNIT | 2192 — Interprocess Communication and Software Development |
CURRENT CPC | Data processing: Software development, installation, and management 717/106 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08752071 | Thomas et al. |
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FUNDED BY |
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APPLICANT(S) | Philip J. Thomas (Lutterworth, United Kingdom); Martin J. Gale (Eastleigh, United Kingdom) |
ASSIGNEE(S) | International Business Machines Corporation (New York, New York); The United States of America as represented by National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS) (Washington, District of Columbia) |
INVENTOR(S) | Philip J. Thomas (Lutterworth, United Kingdom); Martin J. Gale (Eastleigh, United Kingdom) |
ABSTRACT | A solution for managing messaging is provided in which an event related to a publisher is identified. In response to the event, a transaction is initiated for processing the event, the event is processed within the transaction, and the transaction is committed after the event is processed. During processing, data corresponding to the event is provided for use by a set of subscribers to the event, and data related to the set of subscribers is identified. In an embodiment, a message broker in a publication and subscribe messaging environment implements the solution in order to be capable of providing the data related to the set of subscribers to the publisher. Use of the transaction ensures that the data related to the set of subscribers accurately represents the set of subscribers at the time that the data corresponding to the event was provided. |
FILED | Friday, December 19, 2008 |
APPL NO | 12/339749 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/318 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 08745853 | Grbic et al. |
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FUNDED BY |
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APPLICANT(S) | Anthony Grbic (Ann Arbor, Michigan); Carl Pfeiffer (Milford, Michigan); Xin Xu (West Windsor, New Jersey); Stephen Forrest (Ann Arbor, Michigan) |
ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey); The Regents of the University of Michigan, University of Michigan Office of Technology Transfer (Ann Arbor, Michigan) |
INVENTOR(S) | Anthony Grbic (Ann Arbor, Michigan); Carl Pfeiffer (Milford, Michigan); Xin Xu (West Windsor, New Jersey); Stephen Forrest (Ann Arbor, Michigan) |
ABSTRACT | Disclosed herein is a method of fabricating an antenna in which a flexible stamp is formed from a first wafer, the first wafer transferring a pattern to the flexible stamp, in which an antenna substrate is shaped into a three-dimensional contour with a second mold, in which the flexible stamp is positioned in the second mold to deform the flexible stamp into the three-dimensional contour, and in which a metallic layer on the flexible stamp is cold welded to create a set of antenna traces on the antenna substrate in accordance with the pattern. The antenna traces may then be electroplated. |
FILED | Tuesday, July 05, 2011 |
APPL NO | 13/176053 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746120 | Nolting et al. |
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FUNDED BY |
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APPLICANT(S) | Eugene Ellis Nolting (Columbia, Maryland); William Bryan Maier, II (Marina, California); Gene Morris (Seaside, California) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Eugene Ellis Nolting (Columbia, Maryland); William Bryan Maier, II (Marina, California); Gene Morris (Seaside, California) |
ABSTRACT | A device and method which combine electromagnetic acceleration with acceleration by high-pressure gases derived from chemical energy to achieve high slug speeds. In one embodiment the device includes a cylindrical metal tube having an outer diameter and an inner diameter and a central channel; at least one conductive coil surrounding the metal tube; a metal slug disposed within the central channel; a conducting central electrode, having a centrally formed cavity; a conducting rod having at least one cavity including a propellant, wherein a first portion of the conducting rod is attached to the metal slug at a connection point, a second portion of the conducting rod extends between the metal slug and the central electrode, and a third portion of the conducting rod extends within the cavity of the central electrode such that a space is formed between the end of the third portion and the back of the cavity within the central electrode; and an insulator disposed within the central channel and surrounding the conducting central electrode and the second portion of the conducting rod except at the connection point. When a current is applied to the metal tube, the central electrode, and the at least one conductive coil causes the conducting rod to break with resultant generation of a plasma which ignites the propellant such that the energy from the propellant and electromagnetic forces accelerate the slug to speeds greater than are achievable by the propellant alone. |
FILED | Friday, October 19, 2012 |
APPL NO | 13/656464 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/8 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746122 | Roland et al. |
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FUNDED BY |
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APPLICANT(S) | Charles M. Roland (Waldorf, Maryland); Daniel M. Fragiadakis (Alexandria, Virginia); Raymond M. Gamache (Indian Head, Maryland) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Charles M. Roland (Waldorf, Maryland); Daniel M. Fragiadakis (Alexandria, Virginia); Raymond M. Gamache (Indian Head, Maryland) |
ABSTRACT | An armor system with a composite laminate having at least four alternating layers (two bi-layers) of a first material and a second material, the first material having a lower acoustic impedance than the second material. The first material is a viscoelastic polymer with a glass transition temperature less than the expected operational temperature range, and the second material can be a hard material such as steel, aluminum, or ceramic. The laminate can include many alternating layers of elastomer and hard material, and can be adhered or affixed to a thicker armor substrate. Additional protective elements such as corrugated metal-ceramic panels and armored glass cylinders can be added to improve resistance to armor piercing rounds, explosively formed penetrators, or other threats. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/829977 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/36.20 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746124 | Cannon |
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FUNDED BY |
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APPLICANT(S) | Joseph P. Cannon (Lenox, Michigan) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Joseph P. Cannon (Lenox, Michigan) |
ABSTRACT | Reactive armor that includes a casing having a plurality of walls, a back, and a cavity formed therebetween; a cover that closes the cavity and forms a strike face; a filler placed within the cavity, the filler comprising a disruptive material; and an explosive. To defeat projectile or projectile related threats, the reactive armor substantially, but not necessarily wholly, implements laterally oriented force mechanisms, erosion mechanisms, and bulking mechanisms, e.g., explosive forces, with respect to the strike face. |
FILED | Thursday, July 26, 2012 |
APPL NO | 13/559405 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/36.170 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746404 | Allam |
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FUNDED BY |
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APPLICANT(S) | Mahdy A. Allam (Glastonbury, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | Mahdy A. Allam (Glastonbury, Connecticut) |
ABSTRACT | Gas turbine engines systems and methods involving oil flow management are provided. In this regard, a oil pressure analysis system for a gas turbine engine is operative to: receive information corresponding to measured oil pressure and rotational speed during a start up of the engine; correlate the information into data sets, each of the data sets containing a measured oil pressure and a corresponding rotational speed; and determine whether the oil flow valve is functioning properly based on the information contained in the data sets. |
FILED | Wednesday, July 30, 2008 |
APPL NO | 12/182265 |
ART UNIT | 3657 — Material and Article Handling |
CURRENT CPC | Lubrication 184/6.110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746741 | Gonzalez |
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FUNDED BY |
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APPLICANT(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
ABSTRACT | A mechanism protecting vehicle occupants from floor oscillation during under-vehicle explosions comprises vehicle cab sidewalls, a cab floor, cab mounts having elastomeric bodies between the cab and vehicle frame members, a shield below the cab floor, first elastomeric isolators between the shield and frame, and second elastomeric isolators between the shield and sidewalls. The second isolators collapse by an amount equal to the combined collapse of the first isolators and cab mounts. Explosive loads to the shield follow paths to different floor zones, decreasing floor oscillation. A vehicle payload area is mounted to the frame separately from the cab. The payload area and cab move independently on the frame. The payload area mounts are stiffer and smaller than the cab mounts, so explosions under the vehicle tend to accelerate the payload area before the cab. |
FILED | Wednesday, November 14, 2012 |
APPL NO | 13/677202 |
ART UNIT | 3616 — Optics |
CURRENT CPC | Land vehicles 280/784 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747041 | Gonzalez |
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FUNDED BY |
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APPLICANT(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
ABSTRACT | An improved nut-and-bolt assembly reduces tensile stress concentration on the bolt. The assembly has a specially designed nut with a tapered region extending from the nut crown and threaded with the first several bolt threads. The cross sectional area of the tapered region decreases linearly as a function of distance from the crown whereby the tapered region has a convex profile. Each of the bolt threads engaging the tapered region take up an approximately equal amount of longitudinal stress on the bolt. |
FILED | Tuesday, March 26, 2013 |
APPL NO | 13/850608 |
ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Expanded, threaded, driven, headed, tool-deformed, or locked-threaded fastener 411/366.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747092 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Wei Zhang (Newtown, Pennsylvania); Hua Tan (Princeton Junction, New Jersey); Lin Hu (Livingston, New Jersey); Stephen Y. Chou (Princeton, New Jersey) |
ASSIGNEE(S) | Nanonex Corporation (Monmouth Junction, New Jersey) |
INVENTOR(S) | Wei Zhang (Newtown, Pennsylvania); Hua Tan (Princeton Junction, New Jersey); Lin Hu (Livingston, New Jersey); Stephen Y. Chou (Princeton, New Jersey) |
ABSTRACT | The invention disclosed apparatuses and methods to do nanoimprint lithography using a deformable mold. Generally, the apparatus has a chamber with a transparent section on its top wall, which is capable of vacuuming and pressurizing. The deformable mold fixed firmly onto a hollow mold holder around its full periphery is attached to top inner surface of the chamber and positioned underneath the transparent section. The central area of the mold is freely accessible from underneath through the opening of the mold holder. An enclosed volume referring to mold mini-chamber is formed between the mold/holder and top wall of the chamber. Inside chamber, a stage assembly is installed. A chuck to vacuumly hold a substrate is mounted on top of the stage assembly. At beginning of the imprinting, the substrate with a layer of resist is positioned underneath the mold at a predetermined gap between them. Then, the substrate is moved up to contact with the mold either under vacuum or under atmosphere. The substrate and mold may be pressed further by introducing higher pressure inside the chamber. After consolidating the resist, the substrate is separated from the mold by either direct pull-down enabled by stage movement or deforming the mold enabled by differential pressure between the mold mini-chamber and the bulk volume of the chamber, or mixing of both. |
FILED | Friday, January 21, 2011 |
APPL NO | 13/011844 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Plastic article or earthenware shaping or treating: Apparatus 425/150 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747122 | Banitt et al. |
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FUNDED BY |
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APPLICANT(S) | Terry F. Banitt (Altura, Minnesota); John L. Colbert (Byron, Minnesota); Jason R. Eagle (Kasson, Minnesota); Roger S. Krabbenhoft (Rochester, Minnesota) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Terry F. Banitt (Altura, Minnesota); John L. Colbert (Byron, Minnesota); Jason R. Eagle (Kasson, Minnesota); Roger S. Krabbenhoft (Rochester, Minnesota) |
ABSTRACT | A method and apparatus are provided for implementing electrical connection of two large circuit cards through multiple discrete land grid array (LGA) sites. Each of the circuit cards includes a plurality of LGA sites. A first circuit card includes a plurality of LGA interposers locally aligned at the respective LGA sites of the first circuit card. A board-to-board connection hardware assembly connecting a second circuit card to the first circuit card includes a elongated carrier defining a cavity receiving a plurality of load springs coupled to an associated bearing block for loading and maintaining flatness of the LGA sites. |
FILED | Wednesday, June 23, 2010 |
APPL NO | 12/821312 |
ART UNIT | 2833 — Electrical Circuits and Systems |
CURRENT CPC | Electrical connectors 439/66 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747126 | Corbett et al. |
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FUNDED BY |
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APPLICANT(S) | Blaise L. Corbett (King George, Virginia); David J. Griffiths (King George, Virginia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Blaise L. Corbett (King George, Virginia); David J. Griffiths (King George, Virginia) |
ABSTRACT | An adapter is provided for electrically connecting an interior surface of a conduit and an external surface of a cable. The adapter includes a flat strip extending longitudinally from first to second ends with first and second transverse edges and composed of an electrically conductive and mechanically flexible material. The strip includes a longitudinal ribbon that forms a ring for wrapping around the cable by curling the first and second ends together in a direction transverse to the sheet, and a plurality of first and second incisions from the transverse edges towards the ribbon, the incisions being disposed at respective intervals that correspond to a longitudinally regular pattern. The first incisions form tapering tabs for bending in the direction transverse to the sheet to produce petals that extend radially inward from the ring to engage the cable. The second incisions form peripheral tabs for bending in an opposite direction transverse to the sheet to produce flanges that extend radially outward from the ring to engage the conduit. |
FILED | Thursday, October 10, 2013 |
APPL NO | 14/051385 |
ART UNIT | 2833 — Electrical Circuits and Systems |
CURRENT CPC | Electrical connectors 439/98 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747631 | Wei et al. |
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FUNDED BY |
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APPLICANT(S) | Ronghua Wei (San Antonio, Texas); Edward Langa (San Antonio, Texas); Sabrina L. Lee (Schenectaday, New York) |
ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas) |
INVENTOR(S) | Ronghua Wei (San Antonio, Texas); Edward Langa (San Antonio, Texas); Sabrina L. Lee (Schenectaday, New York) |
ABSTRACT | The present disclosure relates to an apparatus and method utilizing double glow discharge for sputter cleaning of a selected surface. The surface may include the inner surface of a hollow substrate such as a tube which inner surface may then be coated via magnetron sputter deposition. |
FILED | Monday, March 15, 2010 |
APPL NO | 12/723816 |
ART UNIT | 1754 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemistry: Electrical and wave energy 24/192.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747656 | Tonkovich et al. |
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FUNDED BY |
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APPLICANT(S) | Anna Lee Tonkovich (Dublin, Ohio); Ravi Arora (New Albany, Ohio); John Brophy (Bath, United Kingdom); Francis P. Daly (Delaware, Ohio); Soumitra Deshmukh (Dublin, Ohio); Maddalena Fanelli (Columbus, Ohio); Kai Tod Paul Jarosch (Bexley, Ohio); Timothy J. LaPlante (Powell, Ohio); Richard Q. Long (New Albany, Ohio); Terry Mazanec (Solon, Ohio); Daniel Francis Ryan (Brewster, Massachusetts); Laura J. Silva (Dublin, Ohio); Wayne W. Simmons (Dublin, Ohio); Bruce Stangeland (Berkeley, California); Yong Wang (Richland, Washington); Thomas Yuschak (Lewis Center, Ohio); Steven T. Perry (Galloway, Ohio); Jeffrey Dale Marco (South Charleston, Ohio); Michael Alan Marchiando (London, Ohio); Robert Dwayne Litt (Westerville, Ohio) |
ASSIGNEE(S) | Velocys, Inc. (Plain City, Ohio) |
INVENTOR(S) | Anna Lee Tonkovich (Dublin, Ohio); Ravi Arora (New Albany, Ohio); John Brophy (Bath, United Kingdom); Francis P. Daly (Delaware, Ohio); Soumitra Deshmukh (Dublin, Ohio); Maddalena Fanelli (Columbus, Ohio); Kai Tod Paul Jarosch (Bexley, Ohio); Timothy J. LaPlante (Powell, Ohio); Richard Q. Long (New Albany, Ohio); Terry Mazanec (Solon, Ohio); Daniel Francis Ryan (Brewster, Massachusetts); Laura J. Silva (Dublin, Ohio); Wayne W. Simmons (Dublin, Ohio); Bruce Stangeland (Berkeley, California); Yong Wang (Richland, Washington); Thomas Yuschak (Lewis Center, Ohio); Steven T. Perry (Galloway, Ohio); Jeffrey Dale Marco (South Charleston, Ohio); Michael Alan Marchiando (London, Ohio); Robert Dwayne Litt (Westerville, Ohio) |
ABSTRACT | This invention relates to a process for conducting a hydrocracking or a hydrotreating process in a microchannel reactor. This invention also relates to a process and apparatus for flowing a vapor and liquid into a plurality of microchannels in a microchannel processing unit. |
FILED | Friday, October 09, 2009 |
APPL NO | 12/576458 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Mineral oils: Processes and products 28/113 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747730 | Riehl |
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FUNDED BY |
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APPLICANT(S) | John Riehl (Hebron, Connecticut) |
ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
INVENTOR(S) | John Riehl (Hebron, Connecticut) |
ABSTRACT | A method of forming a woven fiber structure for a molding process to produce a ceramic matrix composite, includes depositing a tackifier composition having a carrier solvent, a resin material, and an inorganic filler onto at least a portion of a woven fiber structure; drying the tackifier composition on woven fiber structure to remove at least a portion of the carrier solvent from the tackifier composition; and forming the dried woven fiber structure into a preform. |
FILED | Thursday, June 14, 2012 |
APPL NO | 13/517880 |
ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/589 (20130101) C04B 35/806 (20130101) C04B 35/6263 (20130101) C04B 35/6286 (20130101) C04B 35/62802 (20130101) C04B 35/62847 (20130101) C04B 35/62871 (20130101) C04B 35/62886 (20130101) C04B 68/63452 (20130101) C04B 2235/524 (20130101) C04B 2235/616 (20130101) C04B 2235/5244 (20130101) C04B 2235/5252 (20130101) C04B 2235/5256 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 2205/02 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 163/00 (20130101) Original (OR) Class C09J 163/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747869 | Irvine et al. |
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FUNDED BY |
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APPLICANT(S) | Darrell J. Irvine (Arlington, Massachusetts); Jaehyun Moon (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Darrell J. Irvine (Arlington, Massachusetts); Jaehyun Moon (Cambridge, Massachusetts) |
ABSTRACT | The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents. |
FILED | Saturday, March 19, 2011 |
APPL NO | 13/052067 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1273 (20130101) A61K 2039/55572 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747886 | Amsden et al. |
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FUNDED BY |
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APPLICANT(S) | Jason J. Amsden (Eddington, Maine); David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Wakefield, Massachusetts) |
ASSIGNEE(S) | Tufts University (Medford, Massachusetts) |
INVENTOR(S) | Jason J. Amsden (Eddington, Maine); David L. Kaplan (Concord, Massachusetts); Fiorenzo Omenetto (Wakefield, Massachusetts) |
ABSTRACT | The present invention provides for photonic nanoimprinted silk fibroin-based materials and methods for making same, comprising embossing silk fibroin-based films with photonic nanometer scale patterns. In addition, the invention provides for processes by which the silk fibroin-based films can be nanoimprinted at room temperature, by locally decreasing the glass transition temperature of the silk film. Such nanoimprinting process increases high throughput and improves potential for incorporation of silk-based photonics into biomedical and other optical devices. |
FILED | Friday, February 12, 2010 |
APPL NO | 13/201380 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/443 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748106 | Singh et al. |
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FUNDED BY |
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APPLICANT(S) | Bal Ram Singh (N. Dartmouth, Massachusetts); Yu Zhou (New Bedford, Massachusetts) |
ASSIGNEE(S) | Bal Ram Singh (North Dartmouth, Massachusetts) |
INVENTOR(S) | Bal Ram Singh (N. Dartmouth, Massachusetts); Yu Zhou (New Bedford, Massachusetts) |
ABSTRACT | This application is based, inter alia, on the discovery of a binding interaction between the Hn-33 hemagglutinin polypeptide of the type A Clostridium botulinum neurotoxin complex and synaptosomal proteins, including synaptotagmin II (Syt II). Methods of screening for compounds that modulate, e.g., increase or decrease, this interaction are provided. Also provided are compositions and methods for targeting compounds to neuronal and cancer cells by coupling the compounds to Hn-33 or biologically active Hn-33 variants. |
FILED | Tuesday, April 18, 2006 |
APPL NO | 11/911889 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748165 | Vangbo et al. |
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FUNDED BY |
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APPLICANT(S) | Mattias Vangbo (Fremont, California); William D. Nielsen (San Jose, California); Iuliu I. Blaga (Fremont, California); Michael Van Nguyen (San Diego, California); Steven B. Jovanovich (Livermore, California) |
ASSIGNEE(S) | IntegenX Inc. (Pleasanton, California) |
INVENTOR(S) | Mattias Vangbo (Fremont, California); William D. Nielsen (San Jose, California); Iuliu I. Blaga (Fremont, California); Michael Van Nguyen (San Diego, California); Steven B. Jovanovich (Livermore, California) |
ABSTRACT | This invention provides a method for generating short tandem repeat (STR) profiles on each of a plurality of samples comprising, for each sample: a) isolating DNA from the sample; b) amplifying STR markers in the isolated DNA and c) analyzing the amplification product by electrophoresis. |
FILED | Tuesday, August 21, 2012 |
APPL NO | 13/590965 |
ART UNIT | 1775 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/287.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748180 | Shuler et al. |
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FUNDED BY |
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APPLICANT(S) | Michael L. Shuler (Ithaca, New York); Jong Hwan Sung (Seoul, South Korea) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Michael L. Shuler (Ithaca, New York); Jong Hwan Sung (Seoul, South Korea) |
ABSTRACT | A microfluidic device for culturing cells, termed a microscale cell culture analog (μCCA), is provided. The microfluidic device allows multiple cell or tissue types to be cultured in a physiologically relevant environment, facilitates high-throughput operation and can be used for drug discovery. The microfluidic device uses gravity-induced fluidic flow, eliminating the need for a pump and preventing formation of air bubbles. Reciprocating motion between a pair of connected reservoirs is used to effect the gravity-induced flow in microfluidic channels. Bacterial contamination is reduced and high throughput enabled by eliminating a pump. The microfluidic device integrates a pharmacokinetic-pharmacodynamic (PK-PD) model to enable PK-PD analyses on-chip. This combined in vitro/in silico system enables prediction of drug toxicity in a more realistic manner than conventional in vitro systems. |
FILED | Thursday, July 29, 2010 |
APPL NO | 13/387585 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/382 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748181 | Kuo et al. |
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FUNDED BY |
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APPLICANT(S) | Po-Ling Kuo (Cambridge, Massachusetts); Adam W. Feinberg (Cambridge, Massachusetts); Kevin Kit Parker (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Po-Ling Kuo (Cambridge, Massachusetts); Adam W. Feinberg (Cambridge, Massachusetts); Kevin Kit Parker (Cambridge, Massachusetts) |
ABSTRACT | The present invention provides methods of generating and devices of patterned soft substrates, on which cells may be seeded, as well as methods of using these substrates. Devices containing these patterned soft substrates are also provided. |
FILED | Friday, May 22, 2009 |
APPL NO | 12/994187 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/395 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748331 | Talley et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey W. Talley (South Bend, Indiana); Steven Larson (Vicksburg, Mississippi); Lawrence G. Wolfe (Saint Joseph, Michigan); Brian D. Fisher (South Bend, Indiana) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Jeffrey W. Talley (South Bend, Indiana); Steven Larson (Vicksburg, Mississippi); Lawrence G. Wolfe (Saint Joseph, Michigan); Brian D. Fisher (South Bend, Indiana) |
ABSTRACT | A method of manufacturing a remediation material uses a biogenic material as a substrate and involves preparing the surface of the substrate to enable a chemical reaction, and performing template-driven surface derivatization on the substrate to provide a net positive charge on the substrate. The remediation material may be placed into contact with surface water, ground water, soil, or sediment by at least one of a permeable reactive barrier, direct well injection, or direct introduction of the remediation material into soil or sediment, to remove contaminants from the surface water, ground water, soil, or sediment. |
FILED | Wednesday, October 01, 2008 |
APPL NO | 12/243708 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/11 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748407 | Niu et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Latham, New York) |
ABSTRACT | The present invention relates to novel nucleic acid ligands or aptamers that demonstrate potent and selective inhibition of the open-channel conformation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. |
FILED | Monday, February 25, 2013 |
APPL NO | 13/775947 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748565 | Brandt et al. |
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FUNDED BY |
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APPLICANT(S) | Curtis R. Brandt (Stoughton, Wisconsin); Hermann Bultmann (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Reseach Foundation (Madison, Wisconsin) |
INVENTOR(S) | Curtis R. Brandt (Stoughton, Wisconsin); Hermann Bultmann (Madison, Wisconsin) |
ABSTRACT | This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and nonenveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections. |
FILED | Wednesday, April 02, 2008 |
APPL NO | 12/061378 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748566 | Brandt et al. |
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FUNDED BY |
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APPLICANT(S) | Curtis R. Brandt (Stoughton, Wisconsin); Hermann Bultmann (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Curtis R. Brandt (Stoughton, Wisconsin); Hermann Bultmann (Madison, Wisconsin) |
ABSTRACT | This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and nonenveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections. |
FILED | Friday, November 07, 2008 |
APPL NO | 12/291325 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748569 | Stupp et al. |
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FUNDED BY |
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APPLICANT(S) | Samuel I. Stupp (Chicago, Illinois); Joshua E. Goldberger (Columbus, Ohio); Eric J. Berns (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Samuel I. Stupp (Chicago, Illinois); Joshua E. Goldberger (Columbus, Ohio); Eric J. Berns (Chicago, Illinois) |
ABSTRACT | The present invention is directed to peptide amphiphile compounds, compositions and methods of use, wherein nanofiber bundling or epitope aggregation is inhibited. In certain embodiments, the peptide amphiphiles of the present invention have increased solubility and reduced nanofiber bundling. The molecules may be used in pharmaceutical applications, for example for in vivo administration to human patients, by increasing biological activity of the compositions toward neurite outgrowth and nerve regeneration. |
FILED | Monday, April 09, 2012 |
APPL NO | 13/442210 |
ART UNIT | 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5169 (20130101) A61K 38/00 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 2/00 (20130101) C07K 2319/735 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/795 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748639 | Sleadd et al. |
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FUNDED BY |
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APPLICANT(S) | Bradley A. Sleadd (La Plata, Maryland); John Fronabarger (Sun Lakes, Arizona) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Bradley A. Sleadd (La Plata, Maryland); John Fronabarger (Sun Lakes, Arizona) |
ABSTRACT | The present disclosure sets forth the compound 3-azidopicric acid and a method of making the same. The method of producing 3-azidopicric acid is a two step reaction process of first reacting 3-aminopicric acid with sulfuric acid and sodium nitrite, and then reacting the result of the first step with phosphoric acid and sodium azide. Additionally described is a method of producing KDNP (4,6-dinitro-7-hydroxybenzofuroxan, potassium salt), by reacting 3-AzPA with potassium bicarbonate. |
FILED | Tuesday, April 26, 2011 |
APPL NO | 13/094563 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic compounds 552/8 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748919 | Chua |
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FUNDED BY |
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APPLICANT(S) | Christopher L. Chua (San Jose, California) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Christopher L. Chua (San Jose, California) |
ABSTRACT | A light emitting device includes a p-side, an n-side, and an active layer between the p-side and the n-side. The p-side includes a p-side contact, an electron blocking layer, a p-side separate confinement heterostructure (p-SCH), and a p-cladding/current spreading region disposed between the p-SCH and the p-side contact. The n-side includes an n-side contact, and an n-side separate confinement heterostructure (n-SCH). The active layer is configured to emit light in a wavelength range, wherein the p-side and the n-side have asymmetrical optical transmission properties with respect to the wavelength range emitted by the active layer. |
FILED | Thursday, April 28, 2011 |
APPL NO | 13/096988 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/94 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748950 | Levy et al. |
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FUNDED BY |
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APPLICANT(S) | Jeremy Levy (Pittsburgh, Pennsylvania); Cheng Cen (Pittsburgh, Pennsylvania); Patrick Irvin (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Jeremy Levy (Pittsburgh, Pennsylvania); Cheng Cen (Pittsburgh, Pennsylvania); Patrick Irvin (Pittsburgh, Pennsylvania) |
ABSTRACT | A reconfigurable device includes a first insulating layer, a second insulating layer, and a nanoscale quasi one- or zero-dimensional electron gas region disposed at an interface between the first and second insulating layers. The device is reconfigurable by applying an external electrical field to the electron gas, thereby changing the conductivity of the electron gas region. A method for forming and erasing nanoscale-conducting structures employs tools, such as the tip of a conducting atomic force microscope (AFM), to form local electric fields. The method allows both isolated and continuous conducting features to be formed with a length well below 5 nm. |
FILED | Wednesday, November 17, 2010 |
APPL NO | 13/509538 |
ART UNIT | 2822 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/288 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749079 | Dunn et al. |
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FUNDED BY |
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APPLICANT(S) | Paul M. Dunn (West Kingston, Rhode Island); Christopher J. Egan (South Kingston, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Paul M. Dunn (West Kingston, Rhode Island); Christopher J. Egan (South Kingston, Rhode Island) |
ABSTRACT | A compact Wankel expander-alternator combination is provided. The combination includes a stationary outer housing that has embedded stator coils and a rotating inner housing having corresponding magnets disposed around the housing with the magnet/coil interaction generating power. Within the rotating housing, a three-sided rotor turns within a two lobed Wankel cavity, powered by working fluid acting on the rotor. The rotating housing and the rotor each circumscribe a stationary shaft. The shaft has an eccentric lobe about which the rotor turns on a bearing disposed between the rotor and the lobe. The rotating housing turns on bearings supported by the stationary shaft. The rotor and rotating housing are linked so that as the rotor turns in response to the working fluid force, the housing turns at a higher speed the speed ratio being preselected to achieve the desired output energy. |
FILED | Friday, April 01, 2011 |
APPL NO | 13/078261 |
ART UNIT | 2833 — Electrical Circuits and Systems |
CURRENT CPC | Prime-mover dynamo plants 290/1.R00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749439 | Rao et al. |
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FUNDED BY |
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APPLICANT(S) | Basrur Rama Rao (Lexington, Massachusetts); Jeffrey Michael Elloian (Charlton, Massachusetts); Eddie N. Rosario (Methuen, Massachusetts) |
ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
INVENTOR(S) | Basrur Rama Rao (Lexington, Massachusetts); Jeffrey Michael Elloian (Charlton, Massachusetts); Eddie N. Rosario (Methuen, Massachusetts) |
ABSTRACT | Embodiments provide an integrated antenna system that enables dual-use operation (e.g., communications and navigation). In an embodiment, the integrated antenna system includes a sleeve monopole antenna system and stacked shorted annular ring (SAR) patch antenna system, which are compactly integrated to fit on a military handset or a smart phone. In an embodiment, the integrated antenna system enables communication in the 225-450 MHz Ultra-High Frequency (UHF) band and reception of various Global Navigation Satellite System (GNSS) bands. |
FILED | Monday, March 19, 2012 |
APPL NO | 13/423982 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Radio wave antennas 343/725 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749441 | Fenn et al. |
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FUNDED BY |
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APPLICANT(S) | Alan J. Fenn (Wayland, Massachusetts); Peter T. Hurst (Cambridge, Massachusetts); Jeffrey S. Herd (Rowley, Massachusetts); Kenneth E. Kolodziej (Lexington, Massachusetts); Leonard I. Parad (Acton, Massachusetts); Hans Steyskal (Concord, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Alan J. Fenn (Wayland, Massachusetts); Peter T. Hurst (Cambridge, Massachusetts); Jeffrey S. Herd (Rowley, Massachusetts); Kenneth E. Kolodziej (Lexington, Massachusetts); Leonard I. Parad (Acton, Massachusetts); Hans Steyskal (Concord, Massachusetts) |
ABSTRACT | Described is a simultaneous transmit and receive antenna system having a ring array of transmit antenna elements and a receive antenna element disposed on an axis that is perpendicular to and passing through the center of the ring array. Alternatively, the ring array includes receive elements and a transmit antenna element is disposed on the axis perpendicular to the ring array. Opposite antenna elements in the ring array differ in phase by 180° so that a radiation pattern null occurs at the antenna element at the center of the ring array. Also included are at least one ground plane and an electrically-conductive cylinder disposed on the perpendicular axis inside the ring array to provide a high degree of isolation between the transmit and receive antenna elements. The system may be configured for wireless communications, for example, according to WIFI IEEE standard 802.11 or WIMAX IEEE standard 802.16. |
FILED | Thursday, October 27, 2011 |
APPL NO | 13/282700 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Radio wave antennas 343/793 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749545 | Kelly et al. |
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FUNDED BY |
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APPLICANT(S) | Ryan Edward George Kelly (Arlington, Virginia); Felix Roach Hoots, Jr. (Clifton, Virginia) |
ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
INVENTOR(S) | Ryan Edward George Kelly (Arlington, Virginia); Felix Roach Hoots, Jr. (Clifton, Virginia) |
ABSTRACT | Certain embodiments of the invention may include systems and methods visualizing space debris events. According to an example embodiment of the invention, a method is provided for visualizing positional probability of objects in space. The method includes receiving initial conditions of the objects, determining projected positions of the objects based, at least in part, on the initial conditions, determining a plurality of 2-dimensional (2D) boundaries around the projected positions; and assembling the plurality of 2D boundaries into a 3-dimensional (3D) representation of the positional probability of objects in space. |
FILED | Thursday, March 11, 2010 |
APPL NO | 12/721912 |
ART UNIT | 2614 — Electrical Circuits and Systems |
CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749640 | Williams |
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FUNDED BY |
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APPLICANT(S) | Darin S. Williams (Tucson, Arizona) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Darin S. Williams (Tucson, Arizona) |
ABSTRACT | Blur-calibration of an imaging sensor includes moving a known target pattern across the field-of view (FOV) of the imaging sensor to present the target pattern across different frames at different pixel phases. The known target pattern comprises a plurality of point-like objects with fixed relative positions in which at least one point-like object has a different focus position. Frames of images of the moving target pattern as seen in the FOV of the imaging sensor are captured to sample point-like objects at different focus positions and generate a multi-focal image data output, which may be subsequently processed to generate data products at different focus positions from a high-resolution composite image generated from the captured frames. |
FILED | Tuesday, October 11, 2011 |
APPL NO | 13/271155 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Television 348/188 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749871 | Montoya et al. |
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FUNDED BY |
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APPLICANT(S) | Juan C. Montoya (Belmont, Massachusetts); Steven J. Spector (Lexington, Massachusetts); Reuel Swint (Billerica, Massachusetts); Caroline A. Ross (Arlington, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Juan C. Montoya (Belmont, Massachusetts); Steven J. Spector (Lexington, Massachusetts); Reuel Swint (Billerica, Massachusetts); Caroline A. Ross (Arlington, Massachusetts) |
ABSTRACT | An optical structure for generating nonreciprocal loss is provided that includes a first substrate layer and a magneto-optical layer positioned on the first substrate layer. The magneto-optical layer achieves nonreciprocity with application of an external magnetic field so as to produce resonantly enhanced nonreciprocal loss. |
FILED | Wednesday, March 07, 2012 |
APPL NO | 13/414289 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/093 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750077 | Obara et al. |
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FUNDED BY |
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APPLICANT(S) | Michael J. Obara (North Kingstown, Rhode Island); Timothy B. Straw (Narragansett, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael J. Obara (North Kingstown, Rhode Island); Timothy B. Straw (Narragansett, Rhode Island) |
ABSTRACT | An acoustic ranging system and method of use is provided that measures the magnitude of the separation of a pair of towed acoustic line arrays at a discrete point along the length of each array. One array acts as the measurement source, while the other array acts as a frequency-shifted echo repeater. The source array incorporates one sonar transmitter and two sonar receivers. The system further includes a configurable frequency shifter that enables one measurement source to make measurements with multiple repeater arrays. |
FILED | Monday, June 25, 2012 |
APPL NO | 13/531808 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750354 | Heruska et al. |
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FUNDED BY |
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APPLICANT(S) | William M. Heruska (Sicklerville, New Jersey); Michael Uscinowicz (Hainesport, New Jersey); Gregory A. Arlow (Southampton, New Jersey); Fred Tanjutco (Cherry Hill, New Jersey) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | William M. Heruska (Sicklerville, New Jersey); Michael Uscinowicz (Hainesport, New Jersey); Gregory A. Arlow (Southampton, New Jersey); Fred Tanjutco (Cherry Hill, New Jersey) |
ABSTRACT | An open architecture design for a digital nearfield test system for nearfield testing of a phased array antenna allows the ability to use the components of an individual phased array antenna to be tested in conjunction with a nearfield scanner probe system allowing an efficient and cost-saving “radar testing the radar” scenario. |
FILED | Tuesday, May 10, 2011 |
APPL NO | 13/104362 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Pulse or digital communications 375/224 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750425 | Su |
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FUNDED BY |
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APPLICANT(S) | Wei Su (Bel Air, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Wei Su (Bel Air, Maryland) |
ABSTRACT | A method for identifying the modulation scheme of a software defined radio in real-time without pilot symbols between transmitters and receivers, includes providing a predetermined look-up table (LUT) in the software-defined radio wherein the LUT is prepared by pre-calculating discrete likelihood ratio test (DLRT) function values; storing the pre-calculated DLRT values in said LUT; and indexing the pre-calculated DLRT values by addresses. |
FILED | Thursday, May 03, 2012 |
APPL NO | 13/462967 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Pulse or digital communications 375/324 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750453 | Cheng et al. |
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FUNDED BY |
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APPLICANT(S) | Chieh C. Cheng (Redlands, California); David A. Lesyna (Redlands, California); Michael F. Moyers (Colton, California) |
ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
INVENTOR(S) | Chieh C. Cheng (Redlands, California); David A. Lesyna (Redlands, California); Michael F. Moyers (Colton, California) |
ABSTRACT | Apparatus and methods for therapy delivery are disclosed. In one embodiment, a therapy delivery system includes a plurality of movable components including a radiation therapy nozzle and a patient pod for holding a patient, a patient registration module for determining a desired position of at least one of the plurality of movable components, and a motion control module for coordinating the movement of the least one of the plurality of movable components from a current position to the desired position. The motion control module includes a path planning module for simulating at least one projected trajectory of movement of the least one of the plurality of moveable components from the current position to the desired position. |
FILED | Friday, April 13, 2012 |
APPL NO | 13/447090 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/65 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750520 | Sniffen et al. |
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FUNDED BY |
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APPLICANT(S) | Brian T. Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
INVENTOR(S) | Brian T. Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
ABSTRACT | A system, method, and computer program product are provided for requesting a proof of a security policy in a client system. Additionally, a system, method, and computer program product are provided for proving a security policy to an interrogator system. |
FILED | Thursday, November 17, 2011 |
APPL NO | 13/298465 |
ART UNIT | 2453 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) H04L 9/3221 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750595 | Stellari |
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FUNDED BY |
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APPLICANT(S) | Franco Stellari (Waldwick, New Jersey) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Franco Stellari (Waldwick, New Jersey) |
ABSTRACT | A system and method for registering a layout to a measured image includes generating a predictive reference image from a layout design or portion thereof. The predictive reference image is correlated to a measured image obtained from a device having a corresponding structure for the layout design or the portion thereof. A best match transformation is computed between the predictive reference image and the measured image. The layout design or portion thereof is correlated with the measured image based upon the best match transformation. |
FILED | Wednesday, October 06, 2010 |
APPL NO | 12/898867 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image analysis 382/149 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750717 | Yap et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
INVENTOR(S) | Daniel Yap (Newbury Park, California); Keyvan Sayyah (Santa Monica, California) |
ABSTRACT | A spread spectrum waveform generator has a photonic oscillator and an optical heterodyne synthesizer. The photonic oscillator is a multi-tone optical comb generator for generating a series of RF comb lines on an optical carrier. The optical heterodyne synthesizer includes first and second phase-locked lasers, where the first laser feeds the multi-tone optical comb generator and the second laser is a single tone laser whose output light provides a frequency translation reference. At least one photodetector is provided for heterodyning the frequency translation reference with the optical output of the photonic oscillator to generate a spread spectrum waveform. A receiver pre-processor may be provided to operate on the spread spectrum waveform. |
FILED | Tuesday, August 27, 2013 |
APPL NO | 14/010938 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Optical communications 398/158 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750720 | Sefler |
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FUNDED BY |
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APPLICANT(S) | George A. Sefler (Redondo Beach, California) |
ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
INVENTOR(S) | George A. Sefler (Redondo Beach, California) |
ABSTRACT | Various embodiments are directed to a photonic impulse generator comprising a periodically chirped photonic source a single-frequency photonic source, a photodetector, an optical coupler, and a filter. The optical coupler may be positioned to couple an output of the single-frequency photonic source to an output of the periodically chirped photonic source, resulting in a combined photonic signal. The photodetector may be positioned to receive the combined photonic signal and generate a combined electrical signal. The filter may be in electrical communication with an output of the photodetector to receive the combined electrical signal. |
FILED | Tuesday, March 01, 2011 |
APPL NO | 13/037814 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Optical communications 398/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751151 | Funk et al. |
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FUNDED BY |
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APPLICANT(S) | TRX Systems, Inc (Greenbelt, Maryland) |
ASSIGNEE(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
INVENTOR(S) | Benjamin E. Funk (Hanover, Maryland); Jared Napora (Severn, Maryland); Kamiar Kordari (McLean, Virginia); Ruchika Verma (Bethesda, Maryland); Amrit Bandyopadhyay (Washington, District of Columbia); Carole Teolis (Glenn Dale, Maryland) |
ABSTRACT | A system and method for recognizing features for location correction in Simultaneous Localization And Mapping operations, thus facilitating longer duration navigation, is provided. The system may detect features from magnetic, inertial, GPS, light sensors, and/or other sensors that can be associated with a location and recognized when revisited. Feature detection may be implemented on a generally portable tracking system, which may facilitate the use of higher sample rate data for more precise localization of features, improved tracking when network communications are unavailable, and improved ability of the tracking system to act as a smart standalone positioning system to provide rich input to higher level navigation algorithms/systems. The system may detect a transition from structured (such as indoors, in caves, etc.) to unstructured (such as outdoor) environments and from pedestrian motion to travel in a vehicle. The system may include an integrated self-tracking unit that can localize and self-correct such localizations. |
FILED | Thursday, March 28, 2013 |
APPL NO | 13/852649 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/409 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751201 | Vavrick |
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FUNDED BY |
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APPLICANT(S) | Daniel J. Vavrick (Fredericksburg, Virginia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Daniel J. Vavrick (Fredericksburg, Virginia) |
ABSTRACT | A process is provided for characterizing debris, such as predicted from a hydrocode model. The process uses simulation data currently from a CTH hydrocode system to generate a DATAOUT file, but can be easily modified to handle simulation data from other hydrocodes. The debris characterizing process completes iterative calculations to compare cell radii and determine cell connections. Cell connections are continually made to determine and characterize debris pieces. The process includes creating a dynamic scenario from the hydrocode model, producing a SPCTH file, translating the SPCTH file to a DATAOUT file, selectively eliminating materials from the DATAOUT file, reordering the input information in the DATAOUT file, determining connected cells to form single pieces of debris, storing connectivity in an integer array, storing piece information in a cell storage array; and displaying the debris information. |
FILED | Monday, September 12, 2011 |
APPL NO | 13/199958 |
ART UNIT | 2123 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751209 | Henning et al. |
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FUNDED BY |
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APPLICANT(S) | Mark Daniel Henning (Maple Grove, Minnesota); Michael J. Smith (Forest Hill, Maryland); Javad Sedehi (Alexandria, Virginia); William Crocoll (Broadlands, Virginia) |
ASSIGNEE(S) | Exelis Inc. (McLean, Virginia) |
INVENTOR(S) | Mark Daniel Henning (Maple Grove, Minnesota); Michael J. Smith (Forest Hill, Maryland); Javad Sedehi (Alexandria, Virginia); William Crocoll (Broadlands, Virginia) |
ABSTRACT | A method is provided for determining optimum positions in a region for a plurality of sensors that are capable of detecting occurrence of a hazard in the region. The hazard may be a chemical, biological, and/or radiological hazard in solid, liquid or gas form. A “simulation cache” is provided that stores data representing interaction of the hazard with sensors at each of the plurality of candidate locations in the region for each of the plurality of sensor types. Data is then retrieved from the simulation cache as needed for evaluation a particular candidate sensor solution comprising one or more sensors of one or more sensor types at corresponding ones of the candidate locations. An optimization algorithm may be used to select a candidate sensor solution. The data that is retrieved from the simulation cache for a selected candidate sensor solution is evaluated with respect to certain performance criteria. The simulation cache greatly reduces the time required to generate an optimum sensor layout because it separates the hazard modeling and sensor performance modeling from the optimization algorithm. By capturing this data at one time for storage in the simulation cache, it is not necessary to re-run the hazard simulations for each candidate sensor location generated by the optimization algorithm. |
FILED | Wednesday, March 14, 2007 |
APPL NO | 11/686170 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751556 | Song |
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FUNDED BY |
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APPLICANT(S) | William S. Song (Lexington, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | William S. Song (Lexington, Massachusetts) |
ABSTRACT | A multiprocessor system and method for performing matrix operations includes multiple processors cooperatively performing a sparse matrix operation. Distributed among the processors are non-zero matrix elements of first and second sparse matrices. Mapped across the processors are the matrix elements of a results matrix. Each processor receives, from the other processors, non-zero matrix elements of the first matrix that had been distributed to those other processors and generates partial results based on the received non-zero matrix elements of the first matrix and on the non-zero matrix elements of the second matrix distributed to that processor. Each processor receives those partial results generated by other processors and associated with the matrix elements of the results matrix mapped to that processor. Each processor generates a final value for each matrix element of the results matrix mapped to that processor based on the partial results generated by that processor and on the partial results received from the other processors associated with that matrix element of the results matrix. |
FILED | Monday, June 06, 2011 |
APPL NO | 13/153490 |
ART UNIT | 2193 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers: Arithmetic processing and calculating 78/607 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751600 | Jea et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Tsai-Yang Jea (Poughkeepsie, New York); Yuan Yuan Nie (Beijing, China PRC) |
ABSTRACT | In a distributed computing system that includes compute nodes that include computer memory, globally accessible memory space is administered by: for each compute node: mapping a memory region of a predefined size beginning at a predefined address; executing one or more memory management operations within the memory region, including, for each memory management operation executed within the memory region: executing the operation collectively by all compute nodes, where the operation includes a specification of one or more parameters and the parameters are the same across all compute nodes; receiving, by each compute node from a deterministic memory management module in response to the memory management operation, a return value, where the return value is the same across all compute nodes; entering, by each compute node after local completion of the memory management operation, a barrier; and when all compute nodes have entered the barrier, resuming execution. |
FILED | Tuesday, December 11, 2012 |
APPL NO | 13/710611 |
ART UNIT | 2457 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/216 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751655 | Arimilli et al. |
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FUNDED BY |
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APPLICANT(S) | Lakshminarayana B. Arimilli (Austin, Texas); Bernard C. Drerup (Austin, Texas); Paul F. Lecocq (Cedar Park, Texas); Hanhong Xue (Wappingers Falls, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Bernard C. Drerup (Austin, Texas); Paul F. Lecocq (Cedar Park, Texas); Hanhong Xue (Wappingers Falls, New York) |
ABSTRACT | A mechanism is provided in a collective acceleration unit for performing a collective operation to distribute or collect data among a plurality of participant nodes. The mechanism receives an input collective packet for a collective operation from a neighbor node within a collective tree. The input collective packet comprises a tree identifier and an input data field and wherein the collective tree comprises a plurality of sub trees. The mechanism maps the tree identifier to an index within the collective acceleration unit. The index identifies a portion of resources within the collective acceleration unit and is associated with a set of neighbor nodes in a given sub tree within the collective tree. For each neighbor node the collective acceleration unit stores destination information. The collective acceleration unit performs an operation on the input data field using the portion of resources to effect the collective operation. |
FILED | Monday, March 29, 2010 |
APPL NO | 12/749100 |
ART UNIT | 2443 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/226 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 08745936 | Plaisted et al. |
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FUNDED BY |
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APPLICANT(S) | Joshua Reed Plaisted (Oakland, California); Brian West (San Francisco, California) |
ASSIGNEE(S) | SunEdison, LLC (St. Peters, Missouri) |
INVENTOR(S) | Joshua Reed Plaisted (Oakland, California); Brian West (San Francisco, California) |
ABSTRACT | A rack assembly is provided for mounting solar modules over an underlying body. The rack assembly may include a plurality of rail structures that are arrangeable over the underlying body to form an overall perimeter for the rack assembly. One or more retention structures may be provided with the plurality of rail structures, where each retention structure is configured to support one or more solar modules at a given height above the underlying body. At least some of the plurality of rail structures are adapted to enable individual rail structures o be sealed over the underlying body so as to constrain air flow underneath the solar modules. Additionally, at least one of (i) one or more of the rail structures, or (ii) the one or more retention structures are adjustable so as to adapt the rack assembly to accommodate solar modules of varying forms or dimensions. |
FILED | Friday, August 03, 2012 |
APPL NO | 13/566935 |
ART UNIT | 3635 — Static Structures, Supports and Furniture |
CURRENT CPC | Static structures 052/173.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746000 | Schultz |
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FUNDED BY |
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APPLICANT(S) | Mark D. Schultz (Ossining, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Mark D. Schultz (Ossining, New York) |
ABSTRACT | According to one embodiment, a system for removing heat from a rack of information technology equipment may include a sidecar indoor air to liquid heat exchanger that cools warm air generated by the rack of information technology equipment. The system may also include a liquid to liquid heat exchanger and an outdoor heat exchanger. The system may further include configurable pathways to connect and control fluid flow through the sidecar heat exchanger, the liquid to liquid heat exchanger, the rack of information technology equipment, and the outdoor heat exchanger based upon ambient temperature and/or ambient humidity to remove heat from the rack of information technology equipment. |
FILED | Thursday, August 16, 2012 |
APPL NO | 13/587912 |
ART UNIT | 3744 — Static Structures, Supports and Furniture |
CURRENT CPC | Refrigeration 062/259.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746440 | Williamson et al. |
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FUNDED BY |
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APPLICANT(S) | Mark A. Williamson (Naperville, Illinois); Stanley G. Wiedmeyer (Glen Ellyn, Illinois); James L. Willit (Batavia, Illinois); Laurel A. Barnes (Chicago, Illinois); Robert J. Blaskovitz (Lockport, Illinois) |
ASSIGNEE(S) | GE-Hitachi Nuclear Energy Americas LLC (Wilmington, North Carolina) |
INVENTOR(S) | Mark A. Williamson (Naperville, Illinois); Stanley G. Wiedmeyer (Glen Ellyn, Illinois); James L. Willit (Batavia, Illinois); Laurel A. Barnes (Chicago, Illinois); Robert J. Blaskovitz (Lockport, Illinois) |
ABSTRACT | A continuous recovery system for an electrorefiner system may include a trough having a ridge portion and a furrow portion. The furrow portion may include a first section and a second section. An inlet and exit pipe may be connected to the trough. The inlet pipe may include an outlet opening that opens up to the first section of the furrow portion of the trough. The exit pipe may include an entrance opening that opens up to the second section of the furrow portion of the trough. A chain may extend through the inlet and exit pipes and along the furrow portion of the trough. The chain may be in a continuous loop form. A plurality of flights may be secured to the chain. Accordingly, the desired product may be continuously harvested from the electrorefiner system without having to halt the electrical power and/or remove the cathode and anode assemblies. |
FILED | Thursday, December 22, 2011 |
APPL NO | 13/335140 |
ART UNIT | 3651 — Material and Article Handling |
CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 19/14 (20130101) Original (OR) Class B65G 45/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746561 | Gladwell et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas Scott Gladwell (Albuquerque, New Mexico); Justin Garretson (Albuquerque, New Mexico); Clinton G. Hobart (Albuquerque, New Mexico); Mark J. Monda (St. Louis, Missouri) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Thomas Scott Gladwell (Albuquerque, New Mexico); Justin Garretson (Albuquerque, New Mexico); Clinton G. Hobart (Albuquerque, New Mexico); Mark J. Monda (St. Louis, Missouri) |
ABSTRACT | A system and method for disrupting at least one component of a suspect object is provided. The system has a source for passing radiation through the suspect object, a grid board positionable adjacent the suspect object (the grid board having a plurality of grid areas, the radiation from the source passing through the grid board), a screen for receiving the radiation passing through the suspect object and generating at least one image, a weapon for deploying a discharge, and a targeting unit for displaying the image of the suspect object and aiming the weapon according to a disruption point on the displayed image and deploying the discharge into the suspect object to disable the suspect object. |
FILED | Thursday, December 23, 2010 |
APPL NO | 12/977349 |
ART UNIT | 2876 — Optics |
CURRENT CPC | Registers 235/404 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746577 | Bernhard et al. |
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FUNDED BY |
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APPLICANT(S) | Jennifer T Bernhard (Champaign, Illinois); Jessica E. Ruyle (Champaign, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Jennifer T Bernhard (Champaign, Illinois); Jessica E. Ruyle (Champaign, Illinois) |
ABSTRACT | An antenna includes a ground plane having a slot. The slot may be miniaturized using a meandered slot structure or other appropriate reactive loading method as an end load to one or both ends of the slot. An edge treatment may be included on one or more edges of the ground plane or a closely spaced reflecting plane. The antenna is structured to transmit or receive a signal independently or in response to electromagnetic radiation. |
FILED | Tuesday, September 20, 2011 |
APPL NO | 13/200191 |
ART UNIT | 2887 — Optics |
CURRENT CPC | Registers 235/492 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747520 | Bearden et al. |
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FUNDED BY |
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APPLICANT(S) | Mark D. Bearden (Richland, Washington); Paul H. Humble (Kennewick, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Mark D. Bearden (Richland, Washington); Paul H. Humble (Kennewick, Washington) |
ABSTRACT | The present invention are methods for removing preselected substances from a mixed flue gas stream characterized by cooling said mixed flue gas by direct contact with a quench liquid to condense at least one preselected substance and form a cooled flue gas without substantial ice formation on a heat exchanger. After cooling additional process methods utilizing a cryogenic approach and physical concentration and separation or pressurization and sorbent capture may be utilized to selectively remove these materials from the mixed flue gas resulting in a clean flue gas. |
FILED | Tuesday, May 03, 2011 |
APPL NO | 13/100135 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/41 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747591 | Peterson et al. |
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FUNDED BY |
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APPLICANT(S) | Kenneth A. Peterson (Albuquerque, New Mexico); Richard T. Knudson (Los Lunas, New Mexico); Frank R. Smith (Gardner, Kansas); Gregory Barner (Overland Park, Kansas) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Kenneth A. Peterson (Albuquerque, New Mexico); Richard T. Knudson (Los Lunas, New Mexico); Frank R. Smith (Gardner, Kansas); Gregory Barner (Overland Park, Kansas) |
ABSTRACT | Generally annular full tape thickness conductors are formed in single or multiple tape layers, and then stacked to produce an annular solid conductive wall for enclosing an electromagnetic isolation cavity. The conductors may be formed using punch and fill operations, or by flowing conductor-containing material onto the tape edge surfaces that define the interior sidewalls of the cavity. |
FILED | Friday, July 09, 2010 |
APPL NO | 12/833262 |
ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/89.120 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747630 | Gessert et al. |
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FUNDED BY |
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APPLICANT(S) | Timothy A. Gessert (Conifer, Colorado); Yuki Yoshida (San Jose, California); Timothy J. Coutts (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Timothy A. Gessert (Conifer, Colorado); Yuki Yoshida (San Jose, California); Timothy J. Coutts (Golden, Colorado) |
ABSTRACT | Transparent conducting oxides and production thereof are disclosed. An exemplary method of producing a transparent conducting oxide (TCO) material may comprise: providing a TCO target doped with either a high-permittivity oxide or a low-permittivity oxide in a process chamber. The method may also comprise depositing a metal oxide on the target in the process chamber to form a thin film having enhanced optical properties without substantially decreasing electrical quality. |
FILED | Friday, May 30, 2008 |
APPL NO | 12/130788 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemistry: Electrical and wave energy 24/192.290 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747651 | Miller et al. |
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FUNDED BY |
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APPLICANT(S) | Douglas J. Miller (North Olmsted, Ohio); Ching-Feng Chang (Strongsville, Ohio); Irwin C. Lewis (Oberlin, Ohio); Richard T. Lewis (Auburn, Ohio) |
ASSIGNEE(S) | GrafTech International Holdings Inc. (Parma, Ohio) |
INVENTOR(S) | Douglas J. Miller (North Olmsted, Ohio); Ching-Feng Chang (Strongsville, Ohio); Irwin C. Lewis (Oberlin, Ohio); Richard T. Lewis (Auburn, Ohio) |
ABSTRACT | A high coking value pitch prepared from coal tar distillate and has a low softening point and a high carbon value while containing substantially no quinoline insolubles is disclosed. The pitch can be used as an impregnant or binder for producing carbon and graphite articles. |
FILED | Thursday, May 22, 2008 |
APPL NO | 12/154430 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Mineral oils: Processes and products 28/42 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747660 | Gordon et al. |
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FUNDED BY |
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APPLICANT(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
ASSIGNEE(S) | Ceramatec, Inc. (Salt Lake City, Utah) |
INVENTOR(S) | John Howard Gordon (Salt Lake City, Utah); Javier Alvare (Cottonwood Heights, Utah) |
ABSTRACT | A process for upgrading an oil feedstock includes reacting the oil feedstock with a quantity of an alkali metal, wherein the reaction produces solid materials and liquid materials. The solid materials are separated from the liquid materials. The solid materials may be washed and heat treated by heating the materials to a temperature above 400° C. The heat treating occurs in an atmosphere that has low oxygen and water content. Once heat treated, the solid materials are added to a solution comprising a polar solvent, where sulfide, hydrogen sulfide or polysulfide anions dissolve. The solution comprising polar solvent is then added to an electrolytic cell, which during operation, produces alkali metal and sulfur. |
FILED | Wednesday, January 30, 2013 |
APPL NO | 13/753918 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Mineral oils: Processes and products 28/235 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747673 | Ginosar et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel M. Ginosar (Idaho Falls, Idaho); Daniel S. Wendt (Idaho Falls, Idaho); Lucia M. Petkovic (Idaho Falls, Idaho) |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Daniel M. Ginosar (Idaho Falls, Idaho); Daniel S. Wendt (Idaho Falls, Idaho); Lucia M. Petkovic (Idaho Falls, Idaho) |
ABSTRACT | A method of removing a nonpolar solvent from a fluid volume that includes at least one nonpolar compound, such as a fat, an oil or a triglyceride, is provided. The method comprises contacting a fluid volume with an expanding gas to expand the nonpolar solvent and form a gas-expanded solvent. The gas-expanded solvent may have a substantially reduced density in comparison to the at least one nonpolar compound and/or a substantially reduced capacity to solubilize the nonpolar compound, causing the nonpolar compounds to separate from the gas-expanded nonpolar solvent into a separate liquid phase. The liquid phase including the at least one nonpolar compound may be separated from the gas-expanded solvent using conventional techniques. After separation of the liquid phase, at least one of the temperature and pressure may be reduced to separate the nonpolar solvent from the expanding gas such that the nonpolar solvent may be recovered and reused. |
FILED | Thursday, July 07, 2011 |
APPL NO | 13/177962 |
ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Liquid purification or separation 210/634 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747694 | Perry et al. |
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FUNDED BY |
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APPLICANT(S) | Robert James Perry (Niskayuna, New York); Michael Joseph O'Brien (Clifton Park, New York) |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Robert James Perry (Niskayuna, New York); Michael Joseph O'Brien (Clifton Park, New York) |
ABSTRACT | In accordance with one aspect, the present invention provides a composition which contains the amino-siloxane structures I, or III, as described herein. The composition is useful for the capture of carbon dioxide from process streams. In addition, the present invention provides methods of preparing the amino-siloxane composition. Another aspect of the present invention provides methods for reducing the amount of carbon dioxide in a process stream employing the amino-siloxane compositions of the invention, as species which react with carbon dioxide to form an adduct with carbon dioxide. |
FILED | Thursday, June 17, 2010 |
APPL NO | 12/817276 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Compositions 252/190 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747786 | Visser et al. |
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FUNDED BY |
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APPLICANT(S) | Ann E. Visser (Aiken, South Carolina); Nicholas J. Bridges (Aiken, South Carolina) |
ASSIGNEE(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
INVENTOR(S) | Ann E. Visser (Aiken, South Carolina); Nicholas J. Bridges (Aiken, South Carolina) |
ABSTRACT | A method for forming nanoparticles containing uranium oxide is described. The method includes combining a uranium-containing feedstock with an ionic liquid to form a mixture and holding the mixture at an elevated temperature for a period of time to form the product nanoparticles. The method can be carried out at low temperatures, for instance less than about 300° C. |
FILED | Friday, September 07, 2012 |
APPL NO | 13/606558 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/11 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747790 | Collins et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Emory D. Collins (Knoxville, Tennessee); Guillermo D. Delcul (Powell, Tennessee); Rodney D. Hunt (Harriman, Tennessee); Jared A. Johnson (Knoxville, Tennessee); Barry B. Spencer (Knoxville, Tennessee) |
ABSTRACT | A method for reprocessing spent nuclear fuel from a light water reactor includes the step of reacting spent nuclear fuel in a voloxidation vessel with an oxidizing gas having nitrogen dioxide and oxygen for a period sufficient to generate a solid oxidation product of the spent nuclear fuel. The reacting step includes the step of reacting, in a first zone of the voloxidation vessel, spent nuclear fuel with the oxidizing gas at a temperature ranging from 200-450° C. to form an oxidized reaction product, and regenerating nitrogen dioxide, in a second zone of the voloxidation vessel, by reacting oxidizing gas comprising nitrogen monoxide and oxygen at a temperature ranging from 0-80° C. The first zone and the second zone can be separate. A voloxidation system is also disclosed. |
FILED | Friday, August 16, 2013 |
APPL NO | 13/969088 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/249 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747801 | Bowers et al. |
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FUNDED BY |
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APPLICANT(S) | Michael J. Bowers (Nashville, Tennessee); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Michael J. Bowers (Nashville, Tennessee); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ABSTRACT | Disclosed herein are methods of preparing inorganic nanoparticles. In one aspect, the methods can comprise heating a reaction mixture comprising a C8 to C20 alkyl- or arylphosphonic acid and a source of cadmium or zinc to a temperature of greater than about 300° C.; adding to the reaction mixture an injection mixture comprising a C2 to C16 trialkyl- or triarylphosphine and a source of selenium, sulfur, or tellurium; and decreasing the temperature of the reaction mixture to less than about 300° C. Also disclosed herein are nanoparticles made from the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
FILED | Friday, November 16, 2012 |
APPL NO | 13/679924 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/509 |
VIEW PATENT | @ USPTO: Full Text PDF |
08747980 — Hollow fiber apparatus and use thereof for fluids separations and heat and mass transfers
US 08747980 | Bikson et al. |
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FUNDED BY |
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APPLICANT(S) | Benjamin Bikson (Newton, Massachusetts); Stephen Etter (Hamden, Connecticut); Nathaniel Ching (Middletown, New Jersey) |
ASSIGNEE(S) | PoroGen Corporation (Woburn, Massachusetts) |
INVENTOR(S) | Benjamin Bikson (Newton, Massachusetts); Stephen Etter (Hamden, Connecticut); Nathaniel Ching (Middletown, New Jersey) |
ABSTRACT | A hollow fiber device includes a hollow fiber bundle, comprising a plurality of hollow fibers, a first tubesheet and a second tubesheet encapsulating respective distal ends of the hollow fiber bundle. The tubesheets have boreholes in fluid communication with bores of the hollow fibers. In at least one of the tubesheets, the boreholes are formed radially. The hollow fiber device can be utilized in heat exchange, in gas/gas, liquid/liquid and gas/liquid heat transfer, in combined heat and mass transfer and in fluid separation assemblies and processes. The design disclosed herein is light weight and compact and is particularly advantageous when the pressure of a first fluid introduced into the bores of hollow fibers is higher than the pressure on the shell side of the device. |
FILED | Friday, June 08, 2012 |
APPL NO | 13/492714 |
ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/36.910 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748147 | Shamoo et al. |
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FUNDED BY |
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APPLICANT(S) | Yousif Shamoo (Houston, Texas); Siyang Sun (Lafayette, Indiana) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
INVENTOR(S) | Yousif Shamoo (Houston, Texas); Siyang Sun (Lafayette, Indiana) |
ABSTRACT | Chimeric proteins comprising a sequence nonspecific single-stranded nucleic-acid-binding domain joined to a catalytic nucleic-acid-modifying domain are provided. Methods comprising contacting a nucleic acid molecule with a chimeric protein, as well as systems comprising a nucleic acid molecule, a chimeric protein, and an aqueous solution are also provided. The joining of sequence nonspecific single-stranded nucleic-acid-binding domain and a catalytic nucleic-acid-modifying domain in chimeric proteins, among other things, may prevent the separation of the two domains due to their weak association and thereby enhances processivity while maintaining fidelity. |
FILED | Tuesday, November 27, 2007 |
APPL NO | 11/945877 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/194 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748330 | Debe et al. |
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FUNDED BY |
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APPLICANT(S) | Mark K. Debe (Stillwater, Minnesota); Robert L. W. Smithson (Mahtomedi, Minnesota); Charles J. Studiner, IV (Cottage Grove, Minnesota); Susan M. Hendricks (Lake Elmo, Minnesota); Michael J. Kurkowski (White Bear Lake, Minnesota); Andrew J. L. Steinbach (St. Anthony Village, Minnesota) |
ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
INVENTOR(S) | Mark K. Debe (Stillwater, Minnesota); Robert L. W. Smithson (Mahtomedi, Minnesota); Charles J. Studiner, IV (Cottage Grove, Minnesota); Susan M. Hendricks (Lake Elmo, Minnesota); Michael J. Kurkowski (White Bear Lake, Minnesota); Andrew J. L. Steinbach (St. Anthony Village, Minnesota) |
ABSTRACT | This disclosure provides methods of making an enhanced activity nanostructured thin film catalyst by radiation annealing, typically laser annealing, typically under inert atmosphere. Typically the inert gas has a residual oxygen level of 100 ppm. Typically the irradiation has an incident energy fluence of at least 30 mJ/mm2. In some embodiments, the radiation annealing is accomplished by laser annealing. In some embodiments, the nanostructured thin film catalyst is provided on a continuous web. |
FILED | Tuesday, April 26, 2011 |
APPL NO | 13/643431 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/5 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748349 | Goyal et al. |
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FUNDED BY |
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APPLICANT(S) | Amit Goyal (Knoxville, Tennessee); Sung-Hun Wee (Knoxville, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Amit Goyal (Knoxville, Tennessee); Sung-Hun Wee (Knoxville, Tennessee) |
ABSTRACT | A superconducting article includes a substrate having a biaxially textured surface. A biaxially textured buffer layer, which can be a cap layer, is supported by the substrate. The buffer layer includes a double perovskite of the formula A2B′B″O6, where A is rare earth or alkaline earth metal and B′ and B″ are different transition metal cations. A biaxially textured superconductor layer is deposited so as to be supported by the buffer layer. A method of making a superconducting article is also disclosed. |
FILED | Friday, April 15, 2011 |
APPL NO | 13/088179 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/24 (20130101) Original (OR) Class H01L 39/126 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748350 | Goyal et al. |
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FUNDED BY |
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APPLICANT(S) | Amit Goyal (Knoxville, Tennessee); Mariappan Paranthaman (Knoxville, Tennessee); Sung-Hun Wee (Knoxville, Tennessee) |
ASSIGNEE(S) | UT-Battelle (Oak Ridge, Tennessee); University of Tennessee Research Center (Knoxville, Tennessee) |
INVENTOR(S) | Amit Goyal (Knoxville, Tennessee); Mariappan Paranthaman (Knoxville, Tennessee); Sung-Hun Wee (Knoxville, Tennessee) |
ABSTRACT | A method for making a superconducting article includes the steps of providing a biaxially textured substrate. A seed layer is then deposited. The seed layer includes a double perovskite of the formula A2B′B″O6, where A is rare earth or alkaline earth metal and B′ and B″ are different rare earth or transition metal cations. A superconductor layer is grown epitaxially such that the superconductor layer is supported by the seed layer. |
FILED | Friday, April 15, 2011 |
APPL NO | 13/088182 |
ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/24 (20130101) Original (OR) Class H01L 39/126 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748352 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Qibin Zhang (West Richland, Washington); Thomas O. Metz (Kennewick, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Qibin Zhang (West Richland, Washington); Thomas O. Metz (Kennewick, Washington) |
ABSTRACT | A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods. |
FILED | Wednesday, August 15, 2012 |
APPL NO | 13/586321 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/7 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748537 | Naskar et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Tomonori Saito (Knoxville, Tennessee); Joseph M. Pickel (Knoxville, Tennessee); Frederick S. Baker (Oak Ridge, Tennessee); Claude Clifford Eberle (Knoxville, Tennessee); Robert E. Norris (Knoxville, Tennessee); Jonathan Richard Mielenz (Rockwood, Tennessee) |
ABSTRACT | The present invention relates to a crosslinked lignin comprising a lignin structure having methylene or ethylene linking groups therein crosslinking between phenyl ring carbon atoms, wherein said crosslinked lignin is crosslinked to an extent that it has a number-average molecular weight of at least 10,000 g/mol, is melt-processible, and has either a glass transition temperature of at least 100° C., or is substantially soluble in a polar organic solvent or aqueous alkaline solution. Thermoplastic copolymers containing the crosslinked lignin are also described. Methods for producing the crosslinked lignin and thermoplastic copolymers are also described. |
FILED | Monday, October 21, 2013 |
APPL NO | 14/058657 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 525/152 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749629 | Baleine et al. |
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FUNDED BY |
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APPLICANT(S) | Erwan Baleine (Orlando, Florida); Danny M. Sheldon (Chuluota, Florida) |
ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
INVENTOR(S) | Erwan Baleine (Orlando, Florida); Danny M. Sheldon (Chuluota, Florida) |
ABSTRACT | Method and system for calibrating a thermal radiance map of a turbine component in a combustion environment. At least one spot (18) of material is disposed on a surface of the component. An infrared (IR) imager (14) is arranged so that the spot is within a field of view of the imager to acquire imaging data of the spot. A processor (30) is configured to process the imaging data to generate a sequence of images as a temperature of the combustion environment is increased. A monitor (42, 44) may be coupled to the processor to monitor the sequence of images of to determine an occurrence of a physical change of the spot as the temperature is increased. A calibration module (46) may be configured to assign a first temperature value to the surface of the turbine component when the occurrence of the physical change of the spot is determined. |
FILED | Wednesday, February 09, 2011 |
APPL NO | 13/023774 |
ART UNIT | 2485 — Recording and Compression |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/37211 (20130101) G05B 2219/37509 (20130101) Pictorial Communication, e.g Television H04N 7/18 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749949 | Caporaso et al. |
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FUNDED BY |
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APPLICANT(S) | George J. Caporaso (Livermore, California); Stephen E. Sampayan (Manteca, California); David M. Sanders (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | George J. Caporaso (Livermore, California); Stephen E. Sampayan (Manteca, California); David M. Sanders (Livermore, California) |
ABSTRACT | In a structure or device having a pair of electrical conductors separated by an insulator across which a voltage is placed, resistive layers are formed around the conductors to force the electric potential within the insulator to distribute more uniformly so as to decrease or eliminate electric field enhancement at the conductor edges. This is done by utilizing the properties of resistive layers to allow the voltage on the electrode to diffuse outwards, reducing the field stress at the conductor edge. Preferably, the resistive layer has a tapered resistivity, with a lower resistivity adjacent to the conductor and a higher resistivity away from the conductor. Generally, a resistive path across the insulator is provided, preferably by providing a resistive region in the bulk of the insulator, with the resistive layer extending over the resistive region. |
FILED | Monday, October 31, 2011 |
APPL NO | 13/285996 |
ART UNIT | 2848 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/312 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749951 | Falabella et al. |
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FUNDED BY |
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APPLICANT(S) | Steven Falabella (Livermore, California); Glenn A. Meyer (Danville, California); Vincent Tang (Dublin, California); Gary Guethlein (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (, None) |
INVENTOR(S) | Steven Falabella (Livermore, California); Glenn A. Meyer (Danville, California); Vincent Tang (Dublin, California); Gary Guethlein (Livermore, California) |
ABSTRACT | A two-phase mixed media insulator having a dielectric fluid filling the interstices between macro-sized dielectric beads packed into a confined volume, so that the packed dielectric beads inhibit electro-hydrodynamically driven current flows of the dielectric liquid and thereby increase the resistivity and breakdown strength of the two-phase insulator over the dielectric liquid alone. In addition, an electrical apparatus incorporates the two-phase mixed media insulator to insulate between electrical components of different electrical potentials. And a method of electrically insulating between electrical components of different electrical potentials fills a confined volume between the electrical components with the two-phase dielectric composite, so that the macro dielectric beads are packed in the confined volume and interstices formed between the macro dielectric beads are filled with the dielectric liquid. |
FILED | Friday, March 26, 2010 |
APPL NO | 12/748135 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Electricity: Electrical systems and devices 361/326 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750459 | Cowan et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas Cowan (Dresden, Germany); Steven Malekos (Reno, Nevada); Grant Korgan (Reno, Nevada); Jesse Adams (Reno, Nevada); Yasuhiko Sentoku (Reno, Nevada); Nathalie LeGalloudec (Livermore, California) |
ASSIGNEE(S) | Board of Regents of the Nevada System of Higher Education (Reno, Nevada) |
INVENTOR(S) | Thomas Cowan (Dresden, Germany); Steven Malekos (Reno, Nevada); Grant Korgan (Reno, Nevada); Jesse Adams (Reno, Nevada); Yasuhiko Sentoku (Reno, Nevada); Nathalie LeGalloudec (Livermore, California) |
ABSTRACT | In particular embodiments, the present disclosure provides targets including a metal layer and defining a hollow inner surface. The hollow inner surface has an internal apex. The distance between at least two opposing points of the internal apex is less than about 15 μm. In particular examples, the distance is less than about 1 μm. Particular implementations of the targets are free standing. The targets have a number of disclosed shaped, including cones, pyramids, hemispheres, and capped structures. The present disclosure also provides arrays of such targets. Also provided are methods of forming targets, such as the disclosed targets, using lithographic techniques, such as photolithographic techniques. In particular examples, a target mold is formed from a silicon wafer and then one or more sides of the mold are coated with a target material, such as one or more metals. |
FILED | Monday, March 12, 2012 |
APPL NO | 13/418003 |
ART UNIT | 2882 — Optics |
CURRENT CPC | X-ray or gamma ray systems or devices 378/143 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750653 | Peters et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | David W. Peters (Albuquerque, New Mexico); Paul Davids (Albuquerque, New Mexico); Darin Leonhardt (Albuquerque, New Mexico); Jin K. Kim (Albuquerque, New Mexico); Joel R. Wendt (Albuquerque, New Mexico); John F. Klem (Albuquerque, New Mexico) |
ABSTRACT | An exemplary embodiment of the present invention is a photodetector comprising a semiconductor body, a periodically patterned metal nanoantenna disposed on a surface of the semiconductor body, and at least one electrode separate from the nanoantenna. The semiconductor body comprises an active layer in sufficient proximity to the nanoantenna for plasmonic coupling thereto. The nanoantenna is dimensioned to absorb electromagnetic radiation in at least some wavelengths not more than 12 μm that are effective for plasmonic coupling into the active layer. The electrode is part of an electrode arrangement for obtaining a photovoltage or photocurrent in operation under appropriate stimulation. |
FILED | Friday, April 26, 2013 |
APPL NO | 13/871708 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical waveguides 385/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751073 | Kumar et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Ajith Kuttannair Kumar (Erie, Pennsylvania); Wolfgang Daum (Erie, Pennsylvania); Tom Otsubo (Oak Grove, Pennsylvania); John Erik Hershey (Ballston Lake, New York); Gerald James Hess (Lenexa, Kansas) |
ABSTRACT | A system is provided for operating a railway network including a first railway vehicle during a trip along track segments. The system includes a first element for determining travel parameters of the first railway vehicle, a second element for determining travel parameters of a second railway vehicle relative to the track segments to be traversed by the first vehicle during the trip, a processor for receiving information from the first and the second elements and for determining a relationship between occupation of a track segment by the second vehicle and later occupation of the same track segment by the first vehicle and an algorithm embodied within the processor having access to the information to create a trip plan that determines a speed trajectory for the first vehicle. The speed trajectory is responsive to the relationship and further in accordance with one or more operational criteria for the first vehicle. |
FILED | Friday, January 11, 2013 |
APPL NO | 13/739133 |
ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/19 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751140 | Surnilla et al. |
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FUNDED BY |
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APPLICANT(S) | Gopichandra Surnilla (West Bloomfield, Michigan); Thomas G. Leone (Ypsilanti, Michigan); Krishnaswamy Venkatesh Prasad (Ann Arbor, Michigan); Apoorv Agarwal (Clarkston, Michigan); Brett Stanley Hinds (Clarkston, Michigan) |
ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
INVENTOR(S) | Gopichandra Surnilla (West Bloomfield, Michigan); Thomas G. Leone (Ypsilanti, Michigan); Krishnaswamy Venkatesh Prasad (Ann Arbor, Michigan); Apoorv Agarwal (Clarkston, Michigan); Brett Stanley Hinds (Clarkston, Michigan) |
ABSTRACT | Methods and systems are provided for facilitating refueling operations in vehicles operating with multiple fuels. A vehicle operator may be assisted in refueling the multiple fuel tanks of the vehicle by being provided one or more refueling profiles that take into account the vehicle's future trip plans, the predicted environmental conditions along a planned route, and the operator's preferences. |
FILED | Thursday, September 13, 2012 |
APPL NO | 13/614989 |
ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/123 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751168 | Billinge et al. |
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FUNDED BY |
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APPLICANT(S) | Simon Billinge (Brooklyn, New York); Kenneth Shankland (Reading, United Kingdom); Norman Shankland (Glasgow, United Kingdom); Alastair Florence (Glasgow, United Kingdom) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Simon Billinge (Brooklyn, New York); Kenneth Shankland (Reading, United Kingdom); Norman Shankland (Glasgow, United Kingdom); Alastair Florence (Glasgow, United Kingdom) |
ABSTRACT | The present invention provides, inter alia, methods of characterizing a small molecule organic material, e.g., a drug or a drug product. This method includes subjecting the solid small molecule organic material to x-ray total scattering analysis at a short wavelength, collecting data generated thereby, and mathematically transforming the data to provide a refined set of data. |
FILED | Friday, May 28, 2010 |
APPL NO | 12/802064 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/28 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751595 | Blocksome et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Michael A. Blocksome (Rochester, Minnesota); Sameer Kumar (White Plains, New York); Jeffrey J. Parker (Rochester, Minnesota) |
ABSTRACT | Completion processing of data communications instructions in a distributed computing environment with computers coupled for data communications through communications adapters and an active messaging interface (‘AMI’), injecting for data communications instructions into slots in an injection FIFO buffer a transfer descriptor, at least some of the instructions specifying callback functions; injecting a completion descriptor for each instruction that specifies a callback function into an injection FIFO buffer slot having a corresponding slot in a pending callback list; listing in the pending callback list callback functions specified by data communications instructions; processing each descriptor in the injection FIFO buffer, setting a bit in a completion bit mask corresponding to the slot in the FIFO where the completion descriptor was injected; and calling by the AMI any callback functions in the pending callback list as indicated by set bits in the completion bit mask. |
FILED | Monday, November 19, 2012 |
APPL NO | 13/680772 |
ART UNIT | 2457 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/206 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751748 | Ahn et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel Ahn (Yorktown Heights, New York); Luis H. Ceze (Urbana, Illinois); Alan Gara (Mount Kisco, New York); Martin Ohmacht (Yorktown Heights, New York); Zhuang Xiaotong (White Plains, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Daniel Ahn (Yorktown Heights, New York); Luis H. Ceze (Urbana, Illinois); Alan Gara (Mount Kisco, New York); Martin Ohmacht (Yorktown Heights, New York); Zhuang Xiaotong (White Plains, New York) |
ABSTRACT | In a parallel processing system with speculative execution, conflict checking occurs in a directory lookup of a cache memory that is shared by all processors. In each case, the same physical memory address will map to the same set of that cache, no matter which processor originated that access. The directory includes a dynamic reader set encoding, indicating what speculative threads have read a particular line. This reader set encoding is used in conflict checking. A bitset encoding is used to specify particular threads that have read the line. |
FILED | Tuesday, January 18, 2011 |
APPL NO | 13/008583 |
ART UNIT | 2186 — Computer Architecture and I/O |
CURRENT CPC | Electrical computers and digital processing systems: Memory 711/130 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08752051 | Archer et al. |
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FUNDED BY |
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APPLICANT(S) | Charles J. Archer (Rochester, Minnesota); Gabor Dozsa (Ardsley, New York); Joseph D. Ratterman (Seattle, Washington); Brian E. Smith (Rochester, Minnesota) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Gabor Dozsa (Ardsley, New York); Joseph D. Ratterman (Seattle, Washington); Brian E. Smith (Rochester, Minnesota) |
ABSTRACT | Methods, apparatus, and products are disclosed for performing an allreduce operation using shared memory that include: receiving, by at least one of a plurality of processing cores on a compute node, an instruction to perform an allreduce operation; establishing, by the core that received the instruction, a job status object for specifying a plurality of shared memory allreduce work units, the plurality of shared memory allreduce work units together performing the allreduce operation on the compute node; determining, by an available core on the compute node, a next shared memory allreduce work unit in the job status object; and performing, by that available core on the compute node, that next shared memory allreduce work unit. |
FILED | Thursday, March 22, 2012 |
APPL NO | 13/427057 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/52 (20130101) G06F 9/4843 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08752211 | Kalinin et al. |
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FUNDED BY |
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APPLICANT(S) | Sergei V. Kalinin (Knoxville, Tennessee); Nina Balke (Knoxville, Tennessee); Albina Y. Borisevich (Knoxville, Tennessee); Stephen Jesse (Knoxville, Tennessee); Petro Maksymovych (Knoxville, Tennessee); Yunseok Kim (Guyeonggi-do, South Korea); Evgheni Strelcov (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Sergei V. Kalinin (Knoxville, Tennessee); Nina Balke (Knoxville, Tennessee); Albina Y. Borisevich (Knoxville, Tennessee); Stephen Jesse (Knoxville, Tennessee); Petro Maksymovych (Knoxville, Tennessee); Yunseok Kim (Guyeonggi-do, South Korea); Evgheni Strelcov (Oak Ridge, Tennessee) |
ABSTRACT | An excitation voltage biases an ionic conducting material sample over a nanoscale grid. The bias sweeps a modulated voltage with increasing maximal amplitudes. A current response is measured at grid locations. Current response reversal curves are mapped over maximal amplitudes of the bias cycles. Reversal curves are averaged over the grid for each bias cycle and mapped over maximal bias amplitudes for each bias cycle. Average reversal curve areas are mapped over maximal amplitudes of the bias cycles. Thresholds are determined for onset and ending of electrochemical activity. A predetermined number of bias sweeps may vary in frequency where each sweep has a constant number of cycles and reversal response curves may indicate ionic diffusion kinetics. |
FILED | Friday, August 03, 2012 |
APPL NO | 13/566327 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/43 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP24537 | Abrahamson et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence P. Abrahamson (Marcellus, New York); Richard F. Kopp (Marietta, New York); Lawrence B. Smart (Geneva, New York); Timothy A. Volk (Syracuse, New York) |
ASSIGNEE(S) | Suny Research Foundation (Albany, New York) |
INVENTOR(S) | Lawrence P. Abrahamson (Marcellus, New York); Richard F. Kopp (Marietta, New York); Lawrence B. Smart (Geneva, New York); Timothy A. Volk (Syracuse, New York) |
ABSTRACT | A distinct female cultivar of Salix viminalis×(Salix sachalinensis×Salix miyabeana) named ‘Preble’, characterized by rapid stem growth producing 29% more woody biomass than the average of three current production cultivars (Salix×dasyclados ‘SV1’ (unpatented), Salix sachalinensis ‘SX61’ (unpatented), and Salix miyabeana ‘SX64’ (unpatented)) when grown in the same field for the same length of time (three growing seasons after coppice) in two different trials in Constableville, N.Y. and Middlebury, Vt. ‘Preble’ can be planted from dormant stem cuttings, produces multiple stems after coppice and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested repeatedly after two to four years of growth. ‘Preble’ displays a low incidence of rust disease and is not damaged by potato leafhoppers. |
FILED | Wednesday, February 29, 2012 |
APPL NO | 13/385672 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/226 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 08745853 | Grbic et al. |
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FUNDED BY |
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APPLICANT(S) | Anthony Grbic (Ann Arbor, Michigan); Carl Pfeiffer (Milford, Michigan); Xin Xu (West Windsor, New Jersey); Stephen Forrest (Ann Arbor, Michigan) |
ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey); The Regents of the University of Michigan, University of Michigan Office of Technology Transfer (Ann Arbor, Michigan) |
INVENTOR(S) | Anthony Grbic (Ann Arbor, Michigan); Carl Pfeiffer (Milford, Michigan); Xin Xu (West Windsor, New Jersey); Stephen Forrest (Ann Arbor, Michigan) |
ABSTRACT | Disclosed herein is a method of fabricating an antenna in which a flexible stamp is formed from a first wafer, the first wafer transferring a pattern to the flexible stamp, in which an antenna substrate is shaped into a three-dimensional contour with a second mold, in which the flexible stamp is positioned in the second mold to deform the flexible stamp into the three-dimensional contour, and in which a metallic layer on the flexible stamp is cold welded to create a set of antenna traces on the antenna substrate in accordance with the pattern. The antenna traces may then be electroplated. |
FILED | Tuesday, July 05, 2011 |
APPL NO | 13/176053 |
ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Metal working 029/600 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747880 | Forgacs et al. |
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FUNDED BY |
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APPLICANT(S) | Gabor Forgacs (Potsdam, New York); Stephen H. Colbert (Columbia, Missouri); Bradley A. Hubbard (Columbia, Missouri); Francoise Marga (Columbia, Missouri); Dustin Christiansen (Eugene, Oregon) |
ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
INVENTOR(S) | Gabor Forgacs (Potsdam, New York); Stephen H. Colbert (Columbia, Missouri); Bradley A. Hubbard (Columbia, Missouri); Francoise Marga (Columbia, Missouri); Dustin Christiansen (Eugene, Oregon) |
ABSTRACT | An engineered three-dimensional structure includes living cells cohered with each other. The living cells suitably include Schwann cells and at least one other type of cell. The cells accompanying the Schwann cells can suitably be bone marrow stem cells or another type of cell having one or more anti-inflammatory properties. The structure is suitably a graft that facilitates restorative axon growth when the graft is implanted between the proximal and distal stubs of a severed nerve in a living organism. The graft can optionally include a plurality of acellular conduits extending between opposite axial ends of the graft. Bio-printing techniques can be used to assemble a three-dimensional construct that becomes through maturation an axon-guiding graft, by stacking a plurality of multicellular bodies, each of which includes a plurality of living cells cohered to one another to sufficiently to avoid collapsing when the multicellular bodies are stacked to form the structure. |
FILED | Wednesday, February 02, 2011 |
APPL NO | 13/020000 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/422 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748091 | Timp et al. |
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FUNDED BY |
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APPLICANT(S) | Gregory Timp (South Bend, Indiana); Winston Timp (Baltimore, Maryland); Utkur Mirsaidov (Urbana, Illinois); Aleksei Aksimentiev (Urbana, Illinois); Jeffrey Comer (Urbana, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The John Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Gregory Timp (South Bend, Indiana); Winston Timp (Baltimore, Maryland); Utkur Mirsaidov (Urbana, Illinois); Aleksei Aksimentiev (Urbana, Illinois); Jeffrey Comer (Urbana, Illinois) |
ABSTRACT | Methods of trapping a deformed portion of a double-stranded polynucleotide in a membrane nanopassage are provided. In an aspect, the membrane has a nanopassage that defines a confine region, wherein the membrane separates a first fluid compartment from a second fluid compartment, and the nanopassage is in fluid communication with the first and second compartments. A polynucleotide is provided to the first fluid compartment and optionally a threshold voltage for the membrane and the polynucleotide is determined. A driving voltage across the membrane that is greater than the threshold voltage is applied to force a portion of the polynucleotide sequence into the nanopassage confine region, and decreased to a holding voltage bias to trap the polynucleotide portion in the nanopassage confine region. In particular, at least one nucleotide base-pair is fixably positioned in the nanopassage confine volume. In further embodiments, any of the trapping methods are used to characterize or sequence double stranded DNA. |
FILED | Friday, December 17, 2010 |
APPL NO | 12/971240 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4146 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748094 | Weitz et al. |
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FUNDED BY |
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APPLICANT(S) | David A. Weitz (Bolton, Massachusetts); Adam R. Abate (San Francisco, California) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Adam R. Abate (San Francisco, California) |
ABSTRACT | This invention generally relates to particle-assisted nucleic acid sequencing. In some embodiments, sequencing may be performed in a microfluidic device, which can offer desirable properties, for example, minimal use of reagents, facile scale-up, and/or high throughput. In one embodiment, a target nucleic acid may be exposed to particles having nucleic acid probes. By determining the binding of the particles to the target nucleic acid, the sequence of the target nucleic acid (or at least a portion of the target nucleic acid) can be determined. The target nucleic acid may be encapsulated within a fluidic droplet with the particles having nucleic acid probes, in certain instances. In some cases, the sequence of the target nucleic acid may be determined, based on binding of the particles, using sequencing by hybridization (SBH) algorithms or other known techniques. |
FILED | Friday, December 18, 2009 |
APPL NO | 13/139326 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748504 | Elimelech et al. |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Menachem Elimelech (New Haven, Connecticut); Chinedum Osuji (Norwalk, Connecticut); Meagan Mauter (Pittsburgh, Pennsylvania) |
ABSTRACT | The present invention relates to the development and fabrication of thin-film polymer nanocomposites containing vertically aligned nanomaterials, such as single-walled carbon nanotubes (SWNTs). In certain embodiments, the present invention utilizes liquid crystal mesophases of hexagonally packed cylindrical micelles that orient with their long axes parallel to an applied magnetic field, thereby directing the alignment of the nanomaterials, such as SWNTs, sequestered in the micellar cores. In certain embodiments, the mesophase may be a stable, single-phase material containing monomers that can be polymerized after nanotube alignment to form the nanocomposite polymer. |
FILED | Thursday, October 11, 2012 |
APPL NO | 13/649472 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 522/71 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748730 | Kornfield et al. |
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FUNDED BY |
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APPLICANT(S) | Julia A. Kornfield (Pasadena, California); Richard C. Flagan (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Julia A. Kornfield (Pasadena, California); Richard C. Flagan (Pasadena, California) |
ABSTRACT | Systems and methods for concentrating solar energy without tracking the sun are provided. In one embodiment, the invention relates to a solar collector assembly for collecting and concentrating light for solar cell assemblies, the collector assembly including an array of solar collectors, each including a funnel shaped collector including a side wall defining a tapered opening having a base aperture and an upper aperture, the side wall including an outer surface, and a solar cell assembly positioned at the base aperture, where the outer surface is coated with a material that substantially reflects light, where the upper aperture is wider than the base aperture, where the funnel shaped collector is configured to substantially confine light, incident via the upper aperture, within the funnel shaped collector until the light exits proximate the base aperture, and where the solar cell assembly is configured to capture light exiting the base aperture. |
FILED | Saturday, March 13, 2010 |
APPL NO | 12/723625 |
ART UNIT | 1758 — Organic Chemistry |
CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/246 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748950 | Levy et al. |
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FUNDED BY |
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APPLICANT(S) | Jeremy Levy (Pittsburgh, Pennsylvania); Cheng Cen (Pittsburgh, Pennsylvania); Patrick Irvin (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Jeremy Levy (Pittsburgh, Pennsylvania); Cheng Cen (Pittsburgh, Pennsylvania); Patrick Irvin (Pittsburgh, Pennsylvania) |
ABSTRACT | A reconfigurable device includes a first insulating layer, a second insulating layer, and a nanoscale quasi one- or zero-dimensional electron gas region disposed at an interface between the first and second insulating layers. The device is reconfigurable by applying an external electrical field to the electron gas, thereby changing the conductivity of the electron gas region. A method for forming and erasing nanoscale-conducting structures employs tools, such as the tip of a conducting atomic force microscope (AFM), to form local electric fields. The method allows both isolated and continuous conducting features to be formed with a length well below 5 nm. |
FILED | Wednesday, November 17, 2010 |
APPL NO | 13/509538 |
ART UNIT | 2822 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/288 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749421 | Kurchuk et al. |
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FUNDED BY |
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APPLICANT(S) | Mariya Kurchuk (Bridgewater, New Jersey); Colin Weltin-Wu (Berkeley, California); Yannis Tsividis (New York, New York); Dominique Morche (Meylan, France); David Lachartre (Montbonnot, France) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); Commissariat a l'Energie Atomique (Paris, France) |
INVENTOR(S) | Mariya Kurchuk (Bridgewater, New Jersey); Colin Weltin-Wu (Berkeley, California); Yannis Tsividis (New York, New York); Dominique Morche (Meylan, France); David Lachartre (Montbonnot, France) |
ABSTRACT | Systems, devices, and methods for continuous-time digital signal processing and signal representation are disclosed. This includes a continuous-time analog-to-digital converter that is configured to receive an analog signal and convert it to a continuous-time digital signal without using a clock or any type of sampling. This A/D conversion can include a per-level representation and a per-edge representation of the analog signal to produce a digital signal. The digital signal can then be processed in a continuous-time signal processor. The continuous time signal representation and processing can have benefits such a providing filters in high frequency applications where sampling is not practical. |
FILED | Tuesday, October 12, 2010 |
APPL NO | 13/501197 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Coded data generation or conversion 341/155 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749619 | Kirmani et al. |
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FUNDED BY |
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APPLICANT(S) | Ahmed Kirmani (Cambridge, Massachusetts); Ramesh Raskar (Cambridge, Massachusetts); James Davis (Los Gatos, California) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Ahmed Kirmani (Cambridge, Massachusetts); Ramesh Raskar (Cambridge, Massachusetts); James Davis (Los Gatos, California) |
ABSTRACT | In illustrative implementations of this invention, multi-path analysis of transient illumination is used to reconstruct scene geometry, even of objects that are occluded from the camera. An ultrafast camera system is used. It comprises a photo-sensor (e.g., accurate in the picosecond range), a pulsed illumination source (e.g. a femtosecond laser) and a processor. The camera emits a very brief light pulse that strikes a surface and bounces. Depending on the path taken, part of the light may return to the camera after one, two, three or more bounces. The photo-sensor captures the returning light bounces in a three-dimensional time image I(x,y,t) for each pixel. The camera takes different angular samples from the same viewpoint, recording a five-dimensional STIR (Space Time Impulse Response). A processor analyzes onset information in the STIR to estimate pairwise distances between patches in the scene, and then employs isometric embedding to estimate patch coordinates. |
FILED | Wednesday, September 29, 2010 |
APPL NO | 12/893863 |
ART UNIT | 2486 — Recording and Compression |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/481 (20130101) Original (OR) Class G01S 7/4865 (20130101) G01S 17/89 (20130101) Pictorial Communication, e.g Television H04N 3/02 (20130101) H04N 5/2256 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08749871 | Montoya et al. |
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FUNDED BY |
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APPLICANT(S) | Juan C. Montoya (Belmont, Massachusetts); Steven J. Spector (Lexington, Massachusetts); Reuel Swint (Billerica, Massachusetts); Caroline A. Ross (Arlington, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Juan C. Montoya (Belmont, Massachusetts); Steven J. Spector (Lexington, Massachusetts); Reuel Swint (Billerica, Massachusetts); Caroline A. Ross (Arlington, Massachusetts) |
ABSTRACT | An optical structure for generating nonreciprocal loss is provided that includes a first substrate layer and a magneto-optical layer positioned on the first substrate layer. The magneto-optical layer achieves nonreciprocity with application of an external magnetic field so as to produce resonantly enhanced nonreciprocal loss. |
FILED | Wednesday, March 07, 2012 |
APPL NO | 13/414289 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/093 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750020 | Lu et al. |
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FUNDED BY |
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APPLICANT(S) | Wei Lu (Ann Arbor, Michigan); Sung Hyun Jo (Sunnyvale, California) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Wei Lu (Ann Arbor, Michigan); Sung Hyun Jo (Sunnyvale, California) |
ABSTRACT | A method of suppressing propagation of leakage current in an array of switching devices. The method includes providing a dielectric breakdown element integrally and serially connected to a switching element within each of the switching device. A read voltage (for example) is applied to a selected cell. The propagation of leakage current is suppressed by each of the dielectric breakdown element in unselected cells in the array. The read voltage is sufficient to cause breakdown in the selected cells but insufficient to cause breakdown in the serially connected, unselected cells in a specific embodiment. Methods to fabricate of such devices and to program, to erase and to read the device are provided. |
FILED | Monday, January 07, 2013 |
APPL NO | 13/735814 |
ART UNIT | 2827 — Semiconductors/Memory |
CURRENT CPC | Static information storage and retrieval 365/148 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08751843 | Meisner et al. |
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FUNDED BY |
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APPLICANT(S) | David Meisner (Mill Valley, California); Thomas F. Wenisch (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | David Meisner (Mill Valley, California); Thomas F. Wenisch (Ann Arbor, Michigan) |
ABSTRACT | A power management method for use by a blade server or other networked computer having a CPU, memory, network interface, and timer. The method includes monitoring processes in the computer, determining that the computer has become idle, and switching the CPU and memory from an active state to a low power state while maintaining the network interface and timer in an active state. Power management for multicore processors is also provided. A power supply system can be used for providing shared power to groups of the networked computers that each have a similar active power demand. Each PSU in the power supply system is capable of supplying the active power demand at an efficiency greater than a preselected desired minimum efficiency. Changes in power requirements resulting from a computer switching between low power and active states can be accommodated by switching a single PSU into or out of the system. |
FILED | Wednesday, December 16, 2009 |
APPL NO | 13/139769 |
ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electrical computers and digital processing systems: Support 713/323 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08752011 | Dewan et al. |
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FUNDED BY |
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APPLICANT(S) | Prasun Dewan (Chapel Hill, North Carolina); Olufisayo Omojokun (Atlanta, Georgia) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Prasun Dewan (Chapel Hill, North Carolina); Olufisayo Omojokun (Atlanta, Georgia) |
ABSTRACT | Methods, systems and computer readable media for automatically generating customizable user interfaces using programming patterns are disclosed. According to one method, application objects of an application computer program are analyzed to identify programming patterns. Each programming pattern is a relationship among signatures of application methods in one of the application objects. The signatures of the application methods include public interfaces of the application methods. A user interface is automatically generated for the computer program. Automatically generating a user interface includes providing for at least one of a user and a programmer of the computer program to customize mappings between the application objects and user interface elements, where the user interface elements include at least one of user interface widgets and speech grammar rules. |
FILED | Thursday, March 20, 2008 |
APPL NO | 12/532327 |
ART UNIT | 2199 — Interprocess Communication and Software Development |
CURRENT CPC | Data processing: Software development, installation, and management 717/113 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 08747823 | Cardamone et al. |
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FUNDED BY |
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APPLICANT(S) | Jeanette M. Cardamone (Lafayette Hill, Pennsylvania); Paquita Erazo-Majewicz (Landenberg, Pennsylvania); Nabil Naouli (Wilmington, Delaware) |
ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Jeanette M. Cardamone (Lafayette Hill, Pennsylvania); Paquita Erazo-Majewicz (Landenberg, Pennsylvania); Nabil Naouli (Wilmington, Delaware) |
ABSTRACT | A composition containing sulfonated keratin with molecular weight distribution of about 96.8% 100 kDa to 100 Da and about 3.2% 250 kDa to 100 kDa, at least one cationic surfactant, and optionally an aqueous carrier. Generally the keratin is produced by a method involving treating wool with about 0.5 to about 1.0N NaOH in a bath volume:wool weight of about 5:1 to about 10:1 at about 40° C. to about 65° C. for about 4 to about 8 hours with dosing about every 1 to 3 hours with about 1% to about 10% by weight of bath of hydrogen peroxide. Also a method for treating a keratin based substrate involving contacting or applying the substrate (e.g., hair) with the composition. |
FILED | Friday, August 10, 2012 |
APPL NO | 13/571619 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/70.140 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747859 | Mengeling et al. |
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FUNDED BY |
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APPLICANT(S) | William L. Mengeling (Ames, Iowa); Ann Vorwald (Ames, Iowa); Kelly Lager (Neveda, Iowa); Mike Roof (Ames, Iowa); Kelly Burkhart (Radcliffe, Iowa); David E. Gorcyca (St. Joseph, Missouri) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); Boehringer Ingelheim Vetmedica, Inc. (St. Joseph, Missouri) |
INVENTOR(S) | William L. Mengeling (Ames, Iowa); Ann Vorwald (Ames, Iowa); Kelly Lager (Neveda, Iowa); Mike Roof (Ames, Iowa); Kelly Burkhart (Radcliffe, Iowa); David E. Gorcyca (St. Joseph, Missouri) |
ABSTRACT | Substantially avirulent forms of atypical porcine reproductive and respiratory syndrome (PRRS) virus and corresponding vaccines are provided which result from cell culture passaging of virulent forms of PRRS. The resultant avirulent atypical PRRS virus is useful as a vaccine in that PRRS specific antibody response is elicited by inoculation of host animals, thereby conferring effective immunity against both previously known strains of PRRS virus and newly isolated atypical PRRS virus strains. The preferred passaging technique ensures that the virus remains in a logarithmic growth phase substantially throughout the process, which minimizes the time required to achieve attenuation. The present invention also provides diagnostic testing methods which can differentiate between animals infected with field strains and attenuated strains of PRRSV. |
FILED | Friday, February 20, 2009 |
APPL NO | 12/389558 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/204.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748152 | Hector et al. |
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FUNDED BY |
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APPLICANT(S) | Ronald E. Hector (Washington, Illinois); Bruce S. Dien (Peoria, Illinois); Michael A. Cotta (Edelstein, Illinois) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Ronald E. Hector (Washington, Illinois); Bruce S. Dien (Peoria, Illinois); Michael A. Cotta (Edelstein, Illinois) |
ABSTRACT | A xylose isomerase (XI) enzyme which exhibits increased activity and affinity for xylose is produced by strain TC2-24 of the rumen bacterium, Prevotella ruminicola. The gene encoding this enzyme may be used to produce improved recombinant yeast capable of utilizing xylose. The recombinant yeast are preferably transformed with heterologous polynucleotide sequences coding both the P. ruminicola XI, and the xylulokinase (XKS) of a Prevotella species. Yeast transformed with the polynucleotide sequences coding both of these XI and XKS exhibit significantly increased xylose utilization and cell growth on a culture medium containing xylose as the sole carbon source, in comparison to yeast transformed with XKS and XI from other sources. |
FILED | Friday, September 14, 2012 |
APPL NO | 13/616629 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/234 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748641 | Ngo et al. |
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FUNDED BY |
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APPLICANT(S) | Helen Ngo (North Wales, Pennsylvania); Thomas A. Foglia (Lafayette Hill, Pennsylvania) |
ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Helen Ngo (North Wales, Pennsylvania); Thomas A. Foglia (Lafayette Hill, Pennsylvania) |
ABSTRACT | A process for preparing saturated branched chain fatty acids or alkyl esters thereof involving subjecting unsaturated fatty acids having 10 to 25 carbon atoms, alkyl esters thereof or mixtures thereof to a skeletal isomerization reaction in the presence of water or a lower alcohol at a temperature of about 240° C. to about 280° C. using a combination of a stericly hindered Lewis base and zeolite as a Brönsted or Lewis acid catalyst, and isolating saturated branched chain fatty acids or alkyl esters thereof or mixtures thereof from the reaction mixture obtained by the skeletal isomerization reaction. The yield of said saturated branched chain fatty acids is ≧70 wt %. The stericly hindered Lewis base is a tertiary amine or phosphine with linear or branched C1 to C6 alkyl or phenyl groups attached thereto. |
FILED | Wednesday, May 05, 2010 |
APPL NO | 12/774347 |
ART UNIT | 1672 — Organic Chemistry |
CURRENT CPC | Organic compounds 554/142 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748696 | Rathinasabapathi et al. |
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FUNDED BY |
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APPLICANT(S) | Bala Rathinasabapathi (Gainesville, Florida); Walid Mohamed Fouad (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Bala Rathinasabapathi (Gainesville, Florida); Walid Mohamed Fouad (Gainesville, Florida) |
ABSTRACT | The present invention provides methods and compositions for improving biomass, as well as, the drought resistance of plants. More specifically, the present invention utilizes expression of aspartate carboxylase in plants and plant cells. |
FILED | Tuesday, December 08, 2009 |
APPL NO | 12/633213 |
ART UNIT | 1638 — Organic Chemistry |
CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/278 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP24537 | Abrahamson et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence P. Abrahamson (Marcellus, New York); Richard F. Kopp (Marietta, New York); Lawrence B. Smart (Geneva, New York); Timothy A. Volk (Syracuse, New York) |
ASSIGNEE(S) | Suny Research Foundation (Albany, New York) |
INVENTOR(S) | Lawrence P. Abrahamson (Marcellus, New York); Richard F. Kopp (Marietta, New York); Lawrence B. Smart (Geneva, New York); Timothy A. Volk (Syracuse, New York) |
ABSTRACT | A distinct female cultivar of Salix viminalis×(Salix sachalinensis×Salix miyabeana) named ‘Preble’, characterized by rapid stem growth producing 29% more woody biomass than the average of three current production cultivars (Salix×dasyclados ‘SV1’ (unpatented), Salix sachalinensis ‘SX61’ (unpatented), and Salix miyabeana ‘SX64’ (unpatented)) when grown in the same field for the same length of time (three growing seasons after coppice) in two different trials in Constableville, N.Y. and Middlebury, Vt. ‘Preble’ can be planted from dormant stem cuttings, produces multiple stems after coppice and the stem biomass can be harvested when the plant is dormant. In the spring following harvest, the plant will re-sprout very vigorously, producing new stems that can be harvested repeatedly after two to four years of growth. ‘Preble’ displays a low incidence of rust disease and is not damaged by potato leafhoppers. |
FILED | Wednesday, February 29, 2012 |
APPL NO | 13/385672 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/226 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 08746076 | Rogge et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew D. Rogge (Norfolk, Virginia); Jason P. Moore (Yorktown, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Matthew D. Rogge (Norfolk, Virginia); Jason P. Moore (Yorktown, Virginia) |
ABSTRACT | Shape of a multi-core optical fiber is determined by positioning the fiber in an arbitrary initial shape and measuring strain over the fiber's length using strain sensors. A three-coordinate p-vector is defined for each core as a function of the distance of the corresponding cores from a center point of the fiber and a bending angle of the cores. The method includes calculating, via a controller, an applied strain value of the fiber using the p-vector and the measured strain for each core, and calculating strain due to bending as a function of the measured and the applied strain values. Additionally, an apparent local curvature vector is defined for each core as a function of the calculated strain due to bending. Curvature and bend direction are calculated using the apparent local curvature vector, and fiber shape is determined via the controller using the calculated curvature and bend direction. |
FILED | Wednesday, August 22, 2012 |
APPL NO | 13/591320 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08746357 | Butz et al. |
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FUNDED BY |
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APPLICANT(S) | James R. Butz (Lakewood, Colorado); Craig S. Turchi (Lakewood, Colorado); Amanda Kimball (Lakewood, Colorado); Thomas McKinnon (Boulder, Colorado); Edward P. Riedel (Boulder, Colorado) |
ASSIGNEE(S) | ADA Technologies, Inc. (Littleton, Colorado); Colorado School of Mines (Golden, Colorado) |
INVENTOR(S) | James R. Butz (Lakewood, Colorado); Craig S. Turchi (Lakewood, Colorado); Amanda Kimball (Lakewood, Colorado); Thomas McKinnon (Boulder, Colorado); Edward P. Riedel (Boulder, Colorado) |
ABSTRACT | The present invention is directed to a suppression system in which a carrier gas and suppression liquid are contained in a common containment vessel and separated by a separation member. The separation is one or more of movable, deformable, or shape changing in response to pressure exerted by the stored gas. |
FILED | Friday, October 19, 2007 |
APPL NO | 11/875494 |
ART UNIT | 3752 — Fluid Handling and Dispensing |
CURRENT CPC | Fire extinguishers 169/46 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748046 | Smart et al. |
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FUNDED BY |
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APPLICANT(S) | Marshall C. Smart (Studio City, California); Ratnakumar V. Bugga (Arcadia, California); G. K. Surya Prakash (Hacienda Heights, California); Kiah Smith (South Pasadena, California); Pooja Bhalla (Hercules, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
INVENTOR(S) | Marshall C. Smart (Studio City, California); Ratnakumar V. Bugga (Arcadia, California); G. K. Surya Prakash (Hacienda Heights, California); Kiah Smith (South Pasadena, California); Pooja Bhalla (Hercules, California) |
ABSTRACT | An embodiment lithium-ion battery comprising a lithium-ion electrolyte of ethylene carbonate; ethyl methyl carbonate; and at least one solvent selected from the group consisting of trifluoroethyl butyrate, ethyl trifluoroacetate, trifluoroethyl acetate, methyl pentafluoropropionate, and 2,2,2-trifluoroethyl propionate. Other embodiments are described and claimed. |
FILED | Friday, January 25, 2008 |
APPL NO | 12/011462 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/326 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08748822 | Gerecht et al. |
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FUNDED BY |
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APPLICANT(S) | Eyal Gerecht (Westminster, Colorado); David F. Plusquellic (Gaithersburg, Maryland); Kevin O. Douglass (Columbia, Maryland) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Eyal Gerecht (Westminster, Colorado); David F. Plusquellic (Gaithersburg, Maryland); Kevin O. Douglass (Columbia, Maryland) |
ABSTRACT | Terahertz spectroscopy methods that are fast and have excellent spectral resolution and that do not require background correction of the instrument response without sample are disclosed. In one instance, the methods include phase coherent chirp pulse generation and phase coherent detection. |
FILED | Tuesday, January 10, 2012 |
APPL NO | 13/346999 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Radiant energy 250/339.70 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 08746310 | Wason et al. |
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FUNDED BY |
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APPLICANT(S) | John Wason (Troy, New York); John T. Wen (Melrose, New York); Jason Gorman (Silver Spring, Maryland); Nicholas Dagalakis (Potomac, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Commerce, The National Instutute of Standards and Technology (Washington, District of Columbia) |
INVENTOR(S) | John Wason (Troy, New York); John T. Wen (Melrose, New York); Jason Gorman (Silver Spring, Maryland); Nicholas Dagalakis (Potomac, Maryland) |
ABSTRACT | A microassembly method and system utilizing multiple probes. Multiple manipulation actuators can be utilized for maintaining/holding one or more probes and an assembly substrate. Multiple microscope cameras can be configured to provide three distinct workspace configurations. At the center of each manipulation actuator is a die stage, which supports the assembly substrate upon which parts are assembled. A glue dispenser can also provide glue to a part prior to placement. |
FILED | Friday, May 11, 2012 |
APPL NO | 13/469479 |
ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Adhesive bonding and miscellaneous chemical manufacture 156/378 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08747552 | Slack et al. |
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FUNDED BY |
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APPLICANT(S) | Glen A. Slack (Scotia, New York); Leo J. Schowalter (Latham, New York) |
ASSIGNEE(S) | Crystal IS, Inc. (Green Island, New York) |
INVENTOR(S) | Glen A. Slack (Scotia, New York); Leo J. Schowalter (Latham, New York) |
ABSTRACT | Fabrication of doped AlN crystals and/or AlGaN epitaxial layers with high conductivity and mobility is accomplished by, for example, forming mixed crystals including a plurality of impurity species and electrically activating at least a portion of the crystal. |
FILED | Friday, December 18, 2009 |
APPL NO | 12/642182 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/81 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08750385 | Dai et al. |
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FUNDED BY |
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APPLICANT(S) | Jiwang Dai (Princeton Junction, New Jersey); John Qiang Li (Montgomery, New Jersey); Alan Jay Stein (Princeton Junction, New Jersey) |
ASSIGNEE(S) | Thomson Research Funding (Indianapolis, Indiana) |
INVENTOR(S) | Jiwang Dai (Princeton Junction, New Jersey); John Qiang Li (Montgomery, New Jersey); Alan Jay Stein (Princeton Junction, New Jersey) |
ABSTRACT | A system and method for recovering from data loss are described including monitoring a first bit rate video data bit stream to determine if there is frame loss or damage, multiplexing decoding parameters of a second bit rate video data bit stream, the second bit rate video data bit stream and the first bit rate video data bit stream, if there is frame loss or damage, demultiplexing the first bit rate video data bit stream and the second bit rate video data bit stream, decoding the first bit rate video data bit stream, removing damaged frames from the first bit rate video data bit stream, decoding the second bit rate video data bit stream, up-sampling frames from said processed second bit rate video data bit stream if said processed second bit rate video data bit stream has a lower resolution than said processed first bit rate video data bit stream and merging frames from the second bit rate video data bit stream and the first bit rate video data bit stream. |
FILED | Wednesday, December 20, 2006 |
APPL NO | 12/448291 |
ART UNIT | 2483 — Recording and Compression |
CURRENT CPC | Pulse or digital communications 375/240.250 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 08751169 | Swayze et al. |
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FUNDED BY |
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APPLICANT(S) | Gregg A. Swayze (Littleton, Colorado); Heather A. Lowers (Golden, Colorado); Roger N. Clark (Lakewood, Colorado) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Department of the Interior (Washington, District of Columbia) |
INVENTOR(S) | Gregg A. Swayze (Littleton, Colorado); Heather A. Lowers (Golden, Colorado); Roger N. Clark (Lakewood, Colorado) |
ABSTRACT | A method for identifying the source of vermiculite insulation in situ using a portable spectrometer with a light-emitting contact probe and a personal computer. Identification is accomplished using NIR reflectance spectroscopy and absorption band depth ratios to differentiate between vermiculite sources and to test for the presence of amphibole, talc, or serpentine contaminants in vermiculite insulation. |
FILED | Wednesday, September 28, 2011 |
APPL NO | 13/247682 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/20 (20130101) Original (OR) Class C04B 14/38 (20130101) C04B 14/202 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 08750520 | Sniffen et al. |
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FUNDED BY |
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APPLICANT(S) | Brian T. Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
INVENTOR(S) | Brian T. Sniffen (Cambridge, Massachusetts); Joshua Guttman (Newton Centre, Massachusetts); Ariel Segall (Arlington, Massachusetts); Amy L. Herzog (Pebble Beach, California) |
ABSTRACT | A system, method, and computer program product are provided for requesting a proof of a security policy in a client system. Additionally, a system, method, and computer program product are provided for proving a security policy to an interrogator system. |
FILED | Thursday, November 17, 2011 |
APPL NO | 13/298465 |
ART UNIT | 2453 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) H04L 9/3221 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 08748192 | Tian et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Yanqing Tian (Chandler, Arizona); Weiwen Zhang (Chandler, Arizona); Deirdre Meldrum (Phoenix, Arizona); Hongguang Lu (Harbin, China PRC); Yuguang Jin (Gilbert, Arizona); Mark Holl (Tempe, Arizona) |
ABSTRACT | The present invention relates to an optical fluorescence dual sensor comprising a probe for sensing pH, a probe for sensing oxygen, an intra-reference probe and a matrix. The present invention also relates to methods of preparing an optical fluorescence dual sensor and methods of using them. |
FILED | Wednesday, October 24, 2012 |
APPL NO | 13/659821 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Chemistry: Analytical and immunological testing 436/136 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 08748161 | Kuehnle et al. |
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FUNDED BY |
|
APPLICANT(S) | Adelheid R. Kuehnle (Honolulu, Hawaii); Norie Anne B. Nolasco (Waipahu, Hawaii) |
ASSIGNEE(S) | Kuehnle AgroSystems, Inc. (Honolulu, Hawaii) |
INVENTOR(S) | Adelheid R. Kuehnle (Honolulu, Hawaii); Norie Anne B. Nolasco (Waipahu, Hawaii) |
ABSTRACT | The subject invention relates to novel methods for treating microbial biomass and uses thereof. In particular, this invention provides methods for production of lipids using hydrophobic ionic liquid solutions, and subsequent uses of biomass components in food, biofuels, and as chemical precursors. Further, this invention provides methods for recovering the ionic liquids using an antisolvent, thus enabling subsequent reuse of the ionic liquids. |
FILED | Wednesday, November 24, 2010 |
APPL NO | 12/954141 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/257.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 10, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140610.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page