FedInvent™ Patents
Patent Details for Tuesday, July 22, 2014
This page was updated on Monday, March 27, 2023 at 04:02 AM GMT
Department of Defense (DOD)
US 08782944 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | Jason M. Davis (Loogootee, Indiana); Brian P. Dean (Bloomington, Indiana); Brandon R. Clarke (Bloomington, Indiana) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jason M. Davis (Loogootee, Indiana); Brian P. Dean (Bloomington, Indiana); Brandon R. Clarke (Bloomington, Indiana) |
ABSTRACT | An apparatus for mounting accessories on a weapon mount. One embodiment of the apparatus includes an accessory interface system having a forward module coupled to a mounting module. The mounting module of the accessory interface system mounts on a weapon mount. The forward module of the accessory interface system provides a plurality of surfaces for mounting weapon accessories. |
FILED | Thursday, April 18, 2013 |
APPL NO | 13/865292 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 11/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783154 | Windham et al. |
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APPLICANT(S) | James J. Windham (Bettendorf, Iowa); Ryan P. Martin (Bettendorf, Iowa); Jessica M. Hale (Davenport, Iowa) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | James J. Windham (Bettendorf, Iowa); Ryan P. Martin (Bettendorf, Iowa); Jessica M. Hale (Davenport, Iowa) |
ABSTRACT | A Seebeck active cooling device for use in conjunction with a weapon to cool the barrel, in order to reduce its weight, to remove the need for a second barrel, and to prolong its useful life. In particular, the cooling device employs a plurality of thermoelectric devices that convert the energy from the heat produced by the hot barrel during the operation to an electric current. The electric current powers a series of electric fans, which in turn, cool the barrel. |
FILED | Wednesday, November 28, 2012 |
APPL NO | 13/687075 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 13/10 (20130101) F41A 13/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783156 | Malone et al. |
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APPLICANT(S) | QinetiQ North America, Inc. (Reston, Virginia) |
ASSIGNEE(S) | Foster-Miller, Inc. (Waltham, Massachusetts) |
INVENTOR(S) | Joseph Vincent Malone (Waltham, Massachusetts); Nicole Jean Baird (Lincoln, Rhode Island); Scott Robert Albin (Carlisle, Massachusetts); Robert G. Holmes, Jr. (Worcester, Massachusetts) |
ABSTRACT | An ordinance, such as a rocket propelled grenade, shield includes a net with hard points at select nodes of the net and cable guides on the side of the net. Cables under tension extend through the cable guides supporting the net typically in conjunction with a top cross bar, spaced top struts, and spaced bottom struts. This framis design facilitates entering and exiting the vehicle or structure. |
FILED | Tuesday, April 30, 2013 |
APPL NO | 13/873839 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ordnance 089/36.80 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783202 | Lowery et al. |
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APPLICANT(S) | Scott Franklin Lowery (Panama City Beach, Florida); Bryan Franklin Johnson (Panama City, Florida) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Scott Franklin Lowery (Panama City Beach, Florida); Bryan Franklin Johnson (Panama City, Florida) |
ABSTRACT | A subsurface propeller module, using Voith Schneider propeller technology, is provided for use in underwater vehicle dynamic motion control. One or more modules are mounted between nose and body sections of the vehicle such that their axes of rotation coincide with the longitudinal centerline of the vehicle. This enables the module to thrust in any direction normal to the direction of travel. Wiring for power and sensors can be routed through structural conduits connecting the nose section to the main body of the vehicle and supporting the propeller modules. The structural conduits can be shaped to provide support for the nose and body sections, and to have minimal hydrodynamic impact on vehicle forward motion or module thrust. A sealed housing is provided for the motors and control actuators of the propeller modules. |
FILED | Wednesday, July 25, 2012 |
APPL NO | 13/557964 |
ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Ships 114/330 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783467 | Loutherback et al. |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Kevin Loutherback (Berkeley, California); James C. Sturm (Princeton, New Jersey); Robert Austin (Princeton, New Jersey); Keith Morton (Boucherville, Canada); Jason Puchalla (Princeton, New Jersey) |
ABSTRACT | The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ. |
FILED | Friday, December 07, 2012 |
APPL NO | 13/708425 |
ART UNIT | 3653 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Classifying, separating, and assorting solids 29/210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783605 | Lerg |
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APPLICANT(S) | Bryan Henry Lerg (Westfield, Indiana) |
ASSIGNEE(S) | Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana) |
INVENTOR(S) | Bryan Henry Lerg (Westfield, Indiana) |
ABSTRACT | One embodiment of the present invention is a unique flight vehicle. Another embodiment is a unique propulsion system. Another embodiment is a unique thrust vectoring system. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for flight vehicles, propulsion systems and thrust vectoring systems. Further embodiments, forms, features, aspects, benefits, and advantages of the present application will become apparent from the description and figures provided herewith. |
FILED | Friday, December 23, 2011 |
APPL NO | 13/336301 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeronautics and astronautics 244/52 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783746 | Mello |
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FUNDED BY |
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APPLICANT(S) | Craig S Mello (Tiverton, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Craig S Mello (Tiverton, Rhode Island) |
ABSTRACT | A recovery stabilizing pole includes a tube having a passageway formed therethrough, and a handle pivotally joined to the tube. A fixed claw member and a hinged claw member are joined to a distal end of the tube, the hinged claw member being capable of pivoting with respect to the fixed claw member. One end of a cable is joined to the handle and the other is joined to the hinged jaw member. Increased tension in the cable causes pivoting of the hinged jaw member with respect to the fixed jaw member. Embodiments include an adjustment means at the distal end of the tube for angling the claw members with respect to the tube and different tensioning means for the cable. |
FILED | Friday, September 28, 2012 |
APPL NO | 13/630284 |
ART UNIT | 3652 — Material and Article Handling |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 1/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784057 | Podgurski |
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APPLICANT(S) | Daniel M. Podgurski (West Chester, Pennsylvania) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Daniel M. Podgurski (West Chester, Pennsylvania) |
ABSTRACT | A disc rotor blade retraction system includes a main blade spar incorporating a hydraulic cylinder and having a screw thread. A ball screw is concentrically carried within the main blade spar and is operably connected to a ball nut which has an outboard end connected to an intermediate spar with a hydraulic piston received for reciprocation in the hydraulic cylinder. A first geared actuator engages the ball screw and a second geared actuator engages the main blade spar screw thread. A hydraulic fluid accumulator providing pressurized hydraulic fluid is connected to an outboard end of the hydraulic cylinder and a controller actuates the first and second geared actuators. |
FILED | Monday, February 28, 2011 |
APPL NO | 13/037205 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Fluid reaction surfaces 416/142 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784293 | Berka et al. |
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APPLICANT(S) | Advanced Brain Monitoring, Inc. (Carlsbad, California) |
ASSIGNEE(S) | Advanced Brain Monitoring, Inc. (Carlsbad, California) |
INVENTOR(S) | Christine Berka (Carlsbad, California); Djordje Popovic (Carlsbad, California); Dan Levendowski (Carlsbad, California); Gene Davis (Carlsbad, California); Catherine McConnell (Carlsbad, California); Matthew A. Yanagi (Carlsbad, California) |
ABSTRACT | Systems and methods for optimizing sleep and post-sleep performance. In an embodiment, a system comprising a device and sleep mask are provided. The mask may comprise electroencephalographic (EEG) sensors and one or more stimulation elements configured to stimulate the senses of a wearer of the mask. The mask may be releasably and electrically coupled to a device which receives EEG signals from the mask, determines current and target sleep states based, at least in part, on the EEG signals, and uses this determination to tailor a sleep architecture of the wearer by controlling the stimulation elements. The mask may be a soft mask which utilizes conductive thread embroidered into one or more textile layers. In an embodiment, the stimulation elements may comprise one or more heating elements, electroluminescent panels, and speakers. In addition, the EEG sensors may comprise hybrid sensors comprising hydrogel in a conductive spacer fabric. |
FILED | Wednesday, June 05, 2013 |
APPL NO | 13/910709 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) Original (OR) Class A61M 21/02 (20130101) A61M 230/10 (20130101) A61M 2021/0027 (20130101) A61M 2230/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784584 | Yamamoto et al. |
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APPLICANT(S) | Christina M. Yamamoto (Bloomington, Indiana); Robert G. Shortridge (Bloomington, Indiana) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Christina M. Yamamoto (Bloomington, Indiana); Robert G. Shortridge (Bloomington, Indiana) |
ABSTRACT | Perchlorate-free flare compositions are disclosed which, when burned, produce yellow smoke and flames. Methods of producing the compositions are also disclosed. |
FILED | Wednesday, July 03, 2013 |
APPL NO | 13/935069 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Explosive and thermic compositions or charges 149/61 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784632 | Eisaman et al. |
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APPLICANT(S) | Matthew D. Eisaman (Redwood City, California); Karl A. Littau (Palo Alto, California); Daniel Larner (San Jose, California) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Matthew D. Eisaman (Redwood City, California); Karl A. Littau (Palo Alto, California); Daniel Larner (San Jose, California) |
ABSTRACT | An apparatus for performing electrodialysis at pressures greater than or equal to the ambient pressure is described. The apparatus includes an electrodialysis membrane stack and housing. The electrodialysis membrane stack includes at least one electrodialysis cell. The electrodialysis apparatus includes electrodes that apply voltage across the electrodialysis stack. The housing pressurizes the electrodialysis stack at a stack pressure. The housing includes a cell chamber that receives the electrodialysis stack, the cell chamber including at least one pressurization port communicating with the cell chamber such that a portion of electrode solution is transmittable into a region of the cell chamber outside the electrodialysis stack. A system for performing electrodialysis at pressures greater than ambient pressure includes at least two solution loops, an electrode solution loop, and an electrodialysis apparatus operatively connected to the solution and electrode solution loops that performs electrodialysis at a stack pressure that is greater than ambient pressure. |
FILED | Wednesday, December 15, 2010 |
APPL NO | 12/969465 |
ART UNIT | 1756 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry: Electrical and wave energy 24/631 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784704 | Boulais et al. |
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APPLICANT(S) | Kevin A. Boulais (LaPlata, Maryland); Pearl Rayms-Keller (Fredericksburg, Virginia); Michael S. Lowry (Fredericksburg, Virginia); Francisco Santiago (Fredericksburg, Virginia); Karen J. Long (Upper Marlboro, Maryland); Walter D. Sessions (King George, Virginia); Natasha Laguodas Wilkerson (College Park, Maryland); Reniery Cevallos (King George, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kevin A. Boulais (LaPlata, Maryland); Pearl Rayms-Keller (Fredericksburg, Virginia); Michael S. Lowry (Fredericksburg, Virginia); Francisco Santiago (Fredericksburg, Virginia); Karen J. Long (Upper Marlboro, Maryland); Walter D. Sessions (King George, Virginia); Natasha Laguodas Wilkerson (College Park, Maryland); Reniery Cevallos (King George, Virginia) |
ABSTRACT | A material is provided for switching dielectric constant between distinct first and second values responsive to electromagnetic radiation having a specified energy. The material includes a medium transparent to the radiation and a plurality of particulates. Each particulate has a dipole that assumes one of distinct first and second parameters that correspond to the first and second values. The particulates are suspended within the medium. The parameters are either dipole span or charge strength. The dipole of each particulate sets to the first parameter by default and sets to the second parameter in response to the radiation. The particulates can be composed from undoped semi-insulating gallium arsenide. The medium can be polymethylmethacrylate, for example. |
FILED | Tuesday, August 28, 2012 |
APPL NO | 13/573279 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2202/01 (20130101) G02F 2202/101 (20130101) Antennas, i.e Radio Aerials H01Q 3/44 (20130101) Original (OR) Class H01Q 15/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784866 | Tour et al. |
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APPLICANT(S) | James M. Tour (Bellaire, Texas); Rebecca Lucente-Schultz (Houston, Texas); Ashley Leonard (Houston, Texas); Dmitry V. Kosynkin (Houston, Texas); Brandi Katherine Price (Houston, Texas); Jared L. Hudson (Hamilton, Virginia); Jodie L. Conyers, Jr. (Houston, Texas); Valerie C. Moore (Houston, Texas); S. Ward Casscells (Houston, Texas); Jeffrey N. Myers (Houston, Texas); Zvonimir L. Milas (Houston, Texas); Kathy A. Mason (Houston, Texas); Luka Milas (Houston, Texas) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | James M. Tour (Bellaire, Texas); Rebecca Lucente-Schultz (Houston, Texas); Ashley Leonard (Houston, Texas); Dmitry V. Kosynkin (Houston, Texas); Brandi Katherine Price (Houston, Texas); Jared L. Hudson (Hamilton, Virginia); Jodie L. Conyers, Jr. (Houston, Texas); Valerie C. Moore (Houston, Texas); S. Ward Casscells (Houston, Texas); Jeffrey N. Myers (Houston, Texas); Zvonimir L. Milas (Houston, Texas); Kathy A. Mason (Houston, Texas); Luka Milas (Houston, Texas) |
ABSTRACT | Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described. |
FILED | Friday, October 03, 2008 |
APPL NO | 12/245438 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/424 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784929 | Wallace et al. |
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FUNDED BY |
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APPLICANT(S) | Isis Innovation Limited (Oxford, United Kingdom) |
ASSIGNEE(S) | Isis Innovation Limited (Oxford, United Kingdom) |
INVENTOR(S) | Mark Ian Wallace (Oxford, United Kingdom); Andrew John Heron (Oxford, United Kingdom); Matthew Alexander Holden (Amherst, Massachusetts) |
ABSTRACT | A method for producing a bilayer of amphipathic molecules comprising providing a hydrated support and providing a hydrophilic body, and bringing the hydrated support and hydrophilic body into contact to form a bilayer of amphipathic molecules. A bilayer produced by the method of the invention, and uses of the bilayer. |
FILED | Tuesday, October 16, 2012 |
APPL NO | 13/652481 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating processes 427/2.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784978 | Apoorva et al. |
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APPLICANT(S) | Shah Apoorva (Burlington, Massachusetts); Giaya Arjan (Shrewsbury, Massachusetts); Kim Yoojeong (Sudbury, Massachusetts) |
ASSIGNEE(S) | Triton Systems, Inc. (Chelsmford, Massachusetts) |
INVENTOR(S) | Shah Apoorva (Burlington, Massachusetts); Giaya Arjan (Shrewsbury, Massachusetts); Kim Yoojeong (Sudbury, Massachusetts) |
ABSTRACT | The invention relates to polymer nanocomposites including either silica or non-platelet metal oxide particle and the use of these polymer noncomposites in the core layer of multilayer barrier films and laminates. The polymer nanocomposites provide high-barrier properties and low gas permeation. |
FILED | Wednesday, November 22, 2006 |
APPL NO | 11/562836 |
ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Stock material or miscellaneous articles 428/220 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785055 | Sutto |
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APPLICANT(S) | Thomas E. Sutto (Woodbridge, Virginia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Thomas E. Sutto (Woodbridge, Virginia) |
ABSTRACT | Novel electric battery systems are disclosed utilizing selected ionic liquids as electrolytes and selected metals and metal oxides as electrodes. The ionic liquids utilize a substituted imidazolium cation, which does not have the corrosive safety and environmental concerns associated with corrosive acid and alkali electrolytes. |
FILED | Tuesday, September 07, 2010 |
APPL NO | 12/924033 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/328 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785123 | Xu et al. |
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APPLICANT(S) | Ting Xu (Berkeley, California); Yue Zhao (Mountain View, California); Kari Thorkelsson (Berkeley, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Ting Xu (Berkeley, California); Yue Zhao (Mountain View, California); Kari Thorkelsson (Berkeley, California) |
ABSTRACT | The present invention provides hierarchical assemblies of a block copolymer, a bifunctional linking compound and a nanoparticle. The block copolymers form one micro-domain and the nanoparticles another micro-domain. |
FILED | Monday, October 18, 2010 |
APPL NO | 13/502362 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785176 | Ewert et al. |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Matt Ewert (St. Petersburg, Florida); Philip Amuso (Tampa, Florida); Andrew Cannons (Tampa, Florida) |
ABSTRACT | The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample. |
FILED | Friday, January 04, 2013 |
APPL NO | 13/734367 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/262 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785189 | Slukvin et al. |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Igor I. Slukvin (Verona, Wisconsin); James A. Thomson (Madison, Wisconsin); Maksym A. Vodyanyk (Madison, Wisconsin); Maryna E. Gumenyuk (Madison, Wisconsin) |
ABSTRACT | This invention relates to the culture of dendritic cells from human embryonic stem (ES) cells. Human ES cells are first cultured into hematopoietic cells by co-culture with stromal cells. The cells now differentiated into the hematopoietic lineage are then cultured with GM-CSF to create a culture of myeloid precursor cells. Culture of the myeloid precursor cells with the cytokines GM-CSF and IL-4 causes functional dendritic cells to be generated. The dendritic cells have a unique phenotype, as indicated by their combination of cell surface markers. |
FILED | Tuesday, April 09, 2013 |
APPL NO | 13/859228 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/064 (20130101) C12N 5/0639 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785490 | Trent et al. |
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APPLICANT(S) | John O. Trent (Louisville, Kentucky); Jason B. Meier (Louisville, Kentucky); Kelby B. Napier (St. Louis, Missouri) |
ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
INVENTOR(S) | John O. Trent (Louisville, Kentucky); Jason B. Meier (Louisville, Kentucky); Kelby B. Napier (St. Louis, Missouri) |
ABSTRACT | Some embodiments of this invention include methods for treating disease and methods for administering a compound of Formula (I). In some aspects of the invention, diseases can be treated by administration of compositions comprising a compound of Formula (I). Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I). |
FILED | Friday, April 08, 2011 |
APPL NO | 13/639864 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/418 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785505 | Chen |
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APPLICANT(S) | Fanqing Chen (Moraga, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Fanqing Chen (Moraga, California) |
ABSTRACT | The increasing use of nanotechnology in consumer products and medical applications underlies the importance of understanding its potential toxic effects to people and the environment. Herein are described methods and assays to predict and evaluate the cellular effects of nanomaterial exposure. Exposing cells to nanomaterials at cytotoxic doses induces cell cycle arrest and increases apoptosis/necrosis, activates genes involved in cellular transport, metabolism, cell cycle regulation, and stress response. Certain nanomaterials induce genes indicative of a strong immune and inflammatory response within skin fibroblasts. Furthermore, the described multiwall carbon nanoonions (MWCNOs) can be used as a therapeutic in the treatment of cancer due to its cytotoxicity. |
FILED | Monday, April 28, 2008 |
APPL NO | 12/111026 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785547 | Palmese et al. |
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FUNDED BY |
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APPLICANT(S) | Giuseppe R. Palmese (Hainesport, New Jersey); John J. LaScala (Bear, Delaware); James M. Sands (Kingsville, Maryland); Xing Geng (Fort Wayne, Indiana) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia); Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Giuseppe R. Palmese (Hainesport, New Jersey); John J. LaScala (Bear, Delaware); James M. Sands (Kingsville, Maryland); Xing Geng (Fort Wayne, Indiana) |
ABSTRACT | Grafted triglycerides comprising an acrylated triglyceride grafted with a fatty acid residue containing 4 to 28 carbon atoms. Also described are methods for making a grafted triglyceride and for curing a material selected from vinyl esters and unsaturated polyesters and mixtures thereof and optionally a reactive diluent. The method includes the steps of mixing a grafted triglyceride of the present invention with a material selected from vinyl esters, unsaturated polyesters and mixtures thereof to form a mixture, and curing the mixture to form a cured resin system. A cured resin system comprising a cured product obtained by the foregoing method and composites containing the cured product and a filler or reinforcing material are also disclosed. This method also includes use of the grafted triglycerides to make toughened resin and composite systems with reduced hazardous air pollutants without significantly reducing the glass transition temperature and significantly increasing the viscosity. |
FILED | Monday, November 07, 2011 |
APPL NO | 13/990360 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/44 (20130101) C08F 120/40 (20130101) Original (OR) Class C08F 222/40 (20130101) C08F 269/00 (20130101) Compositions of Macromolecular Compounds C08L 31/02 (20130101) C08L 67/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785589 | Tan et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as Represented by the Secretarty of the Air Force (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); David Huabin Wang (Beavercreek, Ohio); Kyung Min Lee (Dayton, Ohio); Timothy J. White (Centerville, Ohio) |
ABSTRACT | Cross-linked polyimides based on a novel crosslinker and methods of making the same. The general structure of these heat-resistant and amorphous polyimides is shown as follows: in which n, m, and l denote the degrees of polymerization (DP) of each arm and the linking group R′ is one of the following moieties: —C(CF3)2—, —O—, —SO2—, >C(═O), —OPh-C(CH3)2-PhO-, -(Ph)C(CF3)—, or a direct bond (—). Films (cantilevers) comprising cross-linked polyimides according to the present invention demonstrate photodirected bending upon exposure to linearly polarized light. |
FILED | Friday, April 19, 2013 |
APPL NO | 13/866551 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1085 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785702 | Harvey et al. |
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FUNDED BY |
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APPLICANT(S) | Benjamin G. Harvey (Ridgecrest, California); Roxanne L. Quintana (Ridgecrest, California); Michael E. Wright (Ridgecrest, California) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California); Roxanne L. Quintana (Ridgecrest, California); Michael E. Wright (Ridgecrest, California) |
ABSTRACT | A process for making diesel and turbine fuels including, providing an effective amount of branched olefins, adding active heterogeneous acid catalyst(s) to said branched olefins to produce a solvent-free mixture, heating said solvent-free mixture greater than about 100° C. for a desired amount of time depending on various conditions, to produce C16 dimers/catalyst mixture, removing said catalysts from said dimers/catalyst mixture, and adding hydrogenation catalyst(s) to said dimers under hydrogen atmosphere to produce a mixture of stable fuels. |
FILED | Thursday, April 29, 2010 |
APPL NO | 12/769757 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemistry of hydrocarbon compounds 585/255 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785881 | Lozano et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Paulo C. Lozano (Arlington, Massachusetts); Steven Mark Arestie (Boston, Massachusetts) |
ABSTRACT | An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or room-temperature molten salt. The body can have a pore size gradient that decreases from the base of the body to the tip of the body, such that the at least one of an ionic liquid or room-temperature molten salt is capable of being transported through capillarity from the base to the tip. |
FILED | Friday, November 01, 2013 |
APPL NO | 14/070351 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/02 (20130101) Original (OR) Class H01J 37/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785911 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Zhihong Chen (Valhalla, New York); Aaron Daniel Franklin (Croton on Hudson, New York); Shu-Jen Han (Cortlandt Manor, New York); James Bowler Hannon (Lincolndale, New York); Katherine L. Saenger (Ossining, New York); George Stojan Tulevski (White Plains, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Zhihong Chen (Valhalla, New York); Aaron Daniel Franklin (Croton on Hudson, New York); Shu-Jen Han (Cortlandt Manor, New York); James Bowler Hannon (Lincolndale, New York); Katherine L. Saenger (Ossining, New York); George Stojan Tulevski (White Plains, New York) |
ABSTRACT | Transistor devices having nanoscale material-based channels (e.g., carbon nanotube or graphene channels) and techniques for the fabrication thereof are provided. In one aspect, a transistor device is provided. The transistor device includes a substrate; an insulator on the substrate; a local bottom gate embedded in the insulator, wherein a top surface of the gate is substantially coplanar with a surface of the insulator; a local gate dielectric on the bottom gate; a carbon-based nanostructure material over at least a portion of the local gate dielectric, wherein a portion of the carbon-based nanostructure material serves as a channel of the device; and conductive source and drain contacts to one or more portions of the carbon-based nanostructure material on opposing sides of the channel that serve as source and drain regions of the device. |
FILED | Thursday, June 23, 2011 |
APPL NO | 13/167570 |
ART UNIT | 2814 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/29 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785946 | Powell et al. |
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FUNDED BY |
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APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
INVENTOR(S) | Adrian Powell (Cary, North Carolina); Mark Brady (Carrboro, North Carolina); Stephan G. Mueller (Durham, North Carolina); Valeri F. Tsvetkov (Gasburg, Virginia); Robert T. Leonard (Raleigh, North Carolina) |
ABSTRACT | A high quality single crystal wafer of SiC is disclosed having a diameter of at least about 3 inches and a 1 c screw dislocation density from about 500 cm−2 to about 2000 cm−2. |
FILED | Tuesday, February 26, 2013 |
APPL NO | 13/776784 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/77 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786277 | Webb et al. |
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FUNDED BY |
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APPLICANT(S) | Michael L. Webb (Cerritos, California); Aaron C. White (Rancho Palos Verdes, California) |
ASSIGNEE(S) | Raytheon Applied Signal Technology, Inc. (Sunnyvale, California) |
INVENTOR(S) | Michael L. Webb (Cerritos, California); Aaron C. White (Rancho Palos Verdes, California) |
ABSTRACT | A magnetic signal noise reduction and detection system has inputs configured to receive data from a first total field scalar magnetometer, data from a vector magnetometer, and data from a position, velocity and heading sensor, a signal processor configured with a pre-processor system, an adaptive noise cancellation system and a detection system, the pre-processor system configured to carry out initial processing of data received. The pre-processor is configured to convert data to the frequency domain and pass the converted data to the adaptive noise cancellation system. The adaptive noise cancellation system is configured to carry out multivariate regression on the converted data to reduce detected noise. The detection system is configured to detect magnetic anomalies and output information in real time about the magnetic anomalies to a user interface. |
FILED | Monday, June 27, 2011 |
APPL NO | 13/170015 |
ART UNIT | 2868 — Printing/Measuring and Testing |
CURRENT CPC | Electricity: Measuring and testing 324/246 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786472 | Prince |
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FUNDED BY |
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APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Gregary B. Prince (Marlborough, Massachusetts) |
ABSTRACT | Generally described herein are methods and systems for sample rate conversion of non-integer and integer factors. In one or more embodiments an apparatus can include a sample rate converter that can include an input configured to receive an input signal with a first frequency and an output configured to provide an output signal with a second frequency different from the first frequency. The sample rate converter can include a filter coefficient lookup table and a numerically controlled oscillator configured to provide filter coefficients from the filter coefficient lookup table at a rate that is a function of the first frequency and the second frequency. The sample rate converter can include a multiplier configured to produce an output that is the product of a filter coefficient of the filter coefficients from the numerically controlled oscillator and a sample of an input signal and an accumulator configured to sum an output of the multiplier and provide a result of the summation when the accumulator receives an indicator to dump the result. |
FILED | Tuesday, February 19, 2013 |
APPL NO | 13/770862 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 17/0621 (20130101) Original (OR) Class H03H 17/0628 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786485 | Atkins et al. |
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FUNDED BY |
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APPLICANT(S) | Robert George Atkins (Lexington, Massachusetts); Justin John Brooke (Cambridge, Massachusetts); Matthew Tyler Cornick (Woburn, Massachusetts); Beijia Zhang (Cambridge, Massachusetts) |
ASSIGNEE(S) | Masachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Robert George Atkins (Lexington, Massachusetts); Justin John Brooke (Cambridge, Massachusetts); Matthew Tyler Cornick (Woburn, Massachusetts); Beijia Zhang (Cambridge, Massachusetts) |
ABSTRACT | Described are a method and system for detecting and locating changes in an underground region. Changes are detected using a mobile coherent change detection ground penetrating radar (GPR). The GPR system is located on a mobile platform that makes two more measurement passes over the same route to acquire GPR images of an underground region at different times. A lateral offset between the GPR images for the two different times is determined and applied to one of the GPR images to generate a GPR shifted image that is spatially aligned with the other GPR image using a correlation process or other technique. A GPR difference image is generated from the GPR shifted image and the other GPR image. The GPR difference image includes data representative of changes to the underground region that occurred between the two measurement passes. |
FILED | Tuesday, August 30, 2011 |
APPL NO | 13/221233 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/295 (20130101) G01S 13/89 (20130101) Original (OR) Class G01S 13/885 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786503 | Apostolos et al. |
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FUNDED BY |
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APPLICANT(S) | John T. Apostolos (Lyndeborough, New Hampshire); Benjamin G. McMahon (Keene, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | John T. Apostolos (Lyndeborough, New Hampshire); Benjamin G. McMahon (Keene, New Hampshire) |
ABSTRACT | A dual purpose antenna is provided with the UHF antenna in the form of a pair of copper tubes to provide an off center fed dipole, with a pair of quadrafiler helix L1 and L2 GPS antennas stacked on top of the UHF antenna, and with the top section of the UHF dipole providing a ground plain for the GPS antenna. The antennas are fed internally by two coaxial feeds, one feeding the UHF antenna, the other passing through the UHF antenna to feed the GPS antennas. In one embodiment, a tuning coil is provided at the base of the UHF antenna by the coiling of the two coaxial feeds around a non-conductive mandrel, with copper taping placed on top of the coiled coaxial sections to provide an LC circuit to lower the resonant frequency of the UHF antenna to 225 MHz. |
FILED | Thursday, May 17, 2012 |
APPL NO | 13/473723 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/273 (20130101) Original (OR) Class H01Q 1/3275 (20130101) H01Q 5/0072 (20130101) H01Q 5/0093 (20130101) H01Q 9/22 (20130101) H01Q 11/08 (20130101) H01Q 21/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786505 | Westman et al. |
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FUNDED BY |
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APPLICANT(S) | Aaron L. Westman (Brewerton, New York); John F. Strempel (Marcellus, New York) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Aaron L. Westman (Brewerton, New York); John F. Strempel (Marcellus, New York) |
ABSTRACT | An alignment apparatus configured to be mounted to a radar array antenna having a generally planar face for aligning the antenna includes a rigid frame defining a plane generally parallel to the face of the antenna when the rigid frame is mounted to the antenna. A flexible member is associated with the rigid frame and is configured to flex relative to the rigid frame. The apparatus further includes an optical source for emitting a light beam and a target. One of the optical source and the target is associated with the flexible member and the other of the optical source and the target is associated with the rigid frame. A distance between the path of the light beam and the target is indicative of the degree of misalignment between the flexible member and the rigid frame. |
FILED | Monday, February 13, 2012 |
APPL NO | 13/371883 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Radio wave antennas 343/760 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786506 | Ayotte et al. |
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FUNDED BY |
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APPLICANT(S) | Keith Ayotte (Hudson, New Hampshire); Paul Lagasse (Derry, New Hampshire); David Martin (Londonderry, New Hampshire); Anthony Sorrentino (Fitchburg, Massachusetts); Spencer Webb (Windham, New Hampshire); Mark Wheeler (Devens, Massachusetts); George Davison (Nashua, New Hampshire) |
ASSIGNEE(S) | Antennasys, Inc. (Windham, New Hampshire); GBS Positioner, LLC (Nashua, New Hampshire) |
INVENTOR(S) | Keith Ayotte (Hudson, New Hampshire); Paul Lagasse (Derry, New Hampshire); David Martin (Londonderry, New Hampshire); Anthony Sorrentino (Fitchburg, Massachusetts); Spencer Webb (Windham, New Hampshire); Mark Wheeler (Devens, Massachusetts); George Davison (Nashua, New Hampshire) |
ABSTRACT | A low power, lightweight, collapsible and rugged antenna positioner for use in communicating with geostationary, geosynchronous and low earth orbit satellite. By collapsing, invention may be easily carried or shipped in a compact container. May be used in remote locations with simple or automated setup and orientation. Azimuth is adjusted by rotating an antenna in relation to a positioner base and elevation is adjusted by rotating an elevation motor coupled with the antenna. Manual orientation of antenna for linear polarized satellites yields lower weight and power usage. Updates ephemeris or TLE data via satellite. Algorithms used for search including Clarke Belt fallback, transponder/beacon searching switch, azimuth priority searching and tracking including uneven re-peak scheduling yield lower power usage. Orientation aid via user interface allows for smaller azimuth motor, simplifies wiring and lowers weight. Tilt compensation, bump detection and failure contingency provide robustness. |
FILED | Friday, October 21, 2011 |
APPL NO | 13/278927 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Radio wave antennas 343/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786942 | Palese et al. |
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FUNDED BY |
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APPLICANT(S) | Stephen P. Palese (Redondo Beach, California); Eric C. Cheung (Torrance, California); Gregory D. Goodno (Los Angeles, California); Chun-Ching Shih (Palos Verdes Estates, California); Mark E. Weber (Hawthorne, California) |
ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
INVENTOR(S) | Stephen P. Palese (Redondo Beach, California); Eric C. Cheung (Torrance, California); Gregory D. Goodno (Los Angeles, California); Chun-Ching Shih (Palos Verdes Estates, California); Mark E. Weber (Hawthorne, California) |
ABSTRACT | A pulsed fiber array laser system that has actively stabilized coherent beam combination (CBC) is disclosed. The active stabilization is accomplished using both piston phase control and intra-pulse phase control, allowing a much greater increase in pulse energy. Further stabilization using intra-pulse amplitude control is also disclosed. A chirp profile can be written on the output pulse to enable specific applications. An amplitude profile of the amplifier array may optionally be tailored to match to a reference electrical pulse. Using the current invention, a much smaller number of amplifier chains will be needed to achieve certain pulse energy, resulting in a system with lower complexity, lower cost, smaller size, less weight, and higher reliability. |
FILED | Wednesday, June 13, 2012 |
APPL NO | 13/495374 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/2308 (20130101) H01S 3/2383 (20130101) Original (OR) Class H01S 3/06754 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786991 | Torres |
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FUNDED BY |
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APPLICANT(S) | Michael A. Torres (Newbury Park, California) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael A. Torres (Newbury Park, California) |
ABSTRACT | Embodiments of the invention relate to automated three phase power monitoring systems. Embodiments of the invention include a zero crossing activated switch having an overload condition signal input that is electrically connected to a signal output terminal. The zero crossing activated switch prohibits conduction of the overload condition signal to a neutral ground RMS reactive breaker control mechanism until the zero crossing activated switch determines that at least one of three alternating currents crosses zero relative to a neutral signal. |
FILED | Wednesday, September 26, 2012 |
APPL NO | 13/627514 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electricity: Electrical systems and devices 361/79 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08787418 | Shur et al. |
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FUNDED BY |
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APPLICANT(S) | Michael Shur (Latham, New York); Maxim S. Shatalov (Columbia, South Carolina); Alexander Dobrinsky (Providence, Rhode Island); Remigijus Gaska (Columbia, South Carolina); Jinwei Yang (Columbia, South Carolina) |
ASSIGNEE(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
INVENTOR(S) | Michael Shur (Latham, New York); Maxim S. Shatalov (Columbia, South Carolina); Alexander Dobrinsky (Providence, Rhode Island); Remigijus Gaska (Columbia, South Carolina); Jinwei Yang (Columbia, South Carolina) |
ABSTRACT | A device including one or more layers with lateral regions configured to facilitate the transmission of radiation through the layer and lateral regions configured to facilitate current flow through the layer is provided. The layer can comprise a short period superlattice, which includes barriers alternating with wells. In this case, the barriers can include both transparent regions, which are configured to reduce an amount of radiation that is absorbed in the layer, and higher conductive regions, which are configured to keep the voltage drop across the layer within a desired range. |
FILED | Friday, August 10, 2012 |
APPL NO | 13/572446 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/45.12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08787752 | Scherer et al. |
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FUNDED BY |
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APPLICANT(S) | Axel Scherer (Laguna Beach, California); Aditya Rajagopal (Irvine, California); Seheon Kim (Pasadena, California); Andrew P. Homyk (South Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Axel Scherer (Laguna Beach, California); Aditya Rajagopal (Irvine, California); Seheon Kim (Pasadena, California); Andrew P. Homyk (South Pasadena, California) |
ABSTRACT | The present disclosure describes an optically powered transducer with a photovoltaic collector. An optical fiber power delivery method and system and a free space power delivery method are also provided. A fabrication process for making an optically powered transducer is further described, together with an implantable transducer system based on optical power delivery. |
FILED | Friday, August 20, 2010 |
APPL NO | 12/860723 |
ART UNIT | 2636 — Optical Communications |
CURRENT CPC | Optical communications 398/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788021 | Flusberg et al. |
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FUNDED BY |
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APPLICANT(S) | Benjamin A. Flusberg (Stanford, California); Eric David Cocker (Menlo Park, California); Juergen Claus Jung (Palo Alto, California); Mark Jacob Schnitzer (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior Univerity (Palo Alto, California) |
INVENTOR(S) | Benjamin A. Flusberg (Stanford, California); Eric David Cocker (Menlo Park, California); Juergen Claus Jung (Palo Alto, California); Mark Jacob Schnitzer (Palo Alto, California) |
ABSTRACT | Analysis of live beings is facilitated. According to an example embodiment of the present invention, a light-directing arrangement such as an endoscope is mounted to a live being. Optics in the light-directing arrangement are implemented to pass source light (e.g., laser excitation light) into the live being, and to pass light from the live being for detection thereof. The light from the live being may include, for example, photons emitted in response to the laser excitation light (i.e., fluoresced). The detected light is then used to detect a characteristic of the live being. |
FILED | Tuesday, January 24, 2006 |
APPL NO | 11/338598 |
ART UNIT | 3768 — Optical Communications |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0013 (20130101) A61B 5/0059 (20130101) Original (OR) Class A61B 5/0062 (20130101) A61B 5/0068 (20130101) A61B 5/0071 (20130101) A61B 5/0075 (20130101) A61B 5/4064 (20130101) A61B 5/6814 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) G01J 3/4406 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788120 | Imbrie et al. |
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FUNDED BY |
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APPLICANT(S) | Andrew P. Imbrie (Santa Clara, California); Steven A. Dunn (Livermore, California); Andrew A. Myers (Sunnyvale, California) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Andrew P. Imbrie (Santa Clara, California); Steven A. Dunn (Livermore, California); Andrew A. Myers (Sunnyvale, California) |
ABSTRACT | System and methods for managing targets of a vehicle is provided. In some aspects, a system may include a boundary check module configured to receive boundary information from a flight safety system. The boundary information comprises a selected termination boundary of a plurality of termination boundaries confining navigation of the vehicle. Each of the plurality of termination boundaries is associated with a target of a plurality of targets of the vehicle. The system may further include a target modification module configured to select the target associated with the selected termination boundary, and a target guidance module configured to provide the selected target to a guidance and control system of the vehicle. |
FILED | Tuesday, April 19, 2011 |
APPL NO | 13/090175 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788130 | Tran et al. |
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FUNDED BY |
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APPLICANT(S) | Nghia X. Tran (San Diego, California); James Eric Anderson (Ramona, California) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Nghia X. Tran (San Diego, California); James Eric Anderson (Ramona, California) |
ABSTRACT | A rolling device configured to adhere to and roll over a ferrous surface comprising: a structure, a controller, an inertial measurement unit (IMU), and a plurality of electromagnets. The structure has inner and outer surfaces and a closed-shape cross section. The electromagnets are mounted to the inner surface and distributed over a periphery of the structure. The controller is operatively coupled to each of the electromagnets. The IMU is mounted within the structure and operatively coupled to provide inertial measurements to the controller. The controller is configured to cause the structure to roll over the ferrous surface in a desired direction by selectively energizing individual electromagnets while de-energizing other electromagnets. |
FILED | Tuesday, May 29, 2012 |
APPL NO | 13/482770 |
ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Motor Vehicles; Trailers B62D 57/024 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0259 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788218 | Soles et al. |
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FUNDED BY |
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APPLICANT(S) | Alexander M. Soles (Bloomington, Indiana); Matthew R. Walsh (Westfield, Indiana); Eric B. Scott (Heltonville, Indiana) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Alexander M. Soles (Bloomington, Indiana); Matthew R. Walsh (Westfield, Indiana); Eric B. Scott (Heltonville, Indiana) |
ABSTRACT | A damage detection and remediation system includes a sensing device for detecting damage events related to a structure of interest. Such damage events may include impact from a ballistic object, a tamper event, a physical impact, or other events that may affect structural integrity or cause failure. Illustratively, the sensing device is in communication with a measurement system to determine damage criteria, and a processing system which is configured to use the damage criteria to determine, for example, a direction of the initiation point of a ballistic causing the damage event. |
FILED | Thursday, June 16, 2011 |
APPL NO | 13/161968 |
ART UNIT | 2864 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/36 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788220 | Soles et al. |
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FUNDED BY |
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APPLICANT(S) | Alexander M. Soles (Bloomington, Indiana); Matthew R. Walsh (Westfield, Indiana); Eric B. Scott (Heltonville, Indiana) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Alexander M. Soles (Bloomington, Indiana); Matthew R. Walsh (Westfield, Indiana); Eric B. Scott (Heltonville, Indiana) |
ABSTRACT | An impact detection and remediation system includes a sensing device for detecting damage events related to a structure of interest. Such damage events may include impact from a ballistic object, a tamper event, a physical impact, or other events that may affect structural integrity or cause failure. Illustratively, the sensing device is in communication with a measurement system to determine impact criteria, and a processing system which is configured to use the impact criteria to determine a direction of the initiation point of a ballistic causing the damage event. |
FILED | Thursday, June 16, 2011 |
APPL NO | 13/161965 |
ART UNIT | 2864 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/38 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788249 | Li |
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FUNDED BY |
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APPLICANT(S) | American GNC Corp. (Simi Valley, California) |
ASSIGNEE(S) | American GNC Corp. (Simi Valley, California) |
INVENTOR(S) | Zongke Li (Simi Valley, California) |
ABSTRACT | A Modeling, Design, Analysis, Simulation, and Evaluation (MDASE) aspects of gyrocompassing in relation to Far-Target Location (FTL) systems include a Gyrocompass Modeling and Simulation System (GMSS). The GMSS has four major components: the 6 degree-of-freedom (6DOF) Motion Simulator, the IMU Sensor Simulator, the Gyrocompass System and Calibration Process Simulator, and the Gyrocompass System Evaluation and Analysis Module. The modular architecture of GMSS makes it very flexible for programming, testing, and system maintenance. The realization of the GMSS can be based on any computer platforms for the GMSS software is written in high level language and is portable. The stochastic signal analysis and sensor testing and modeling tools comprise a suite of generic statistical analysis software, including Allan Variance and power spectral density (PSD) analysis tools, which are available to every GMSS module and greatly enhanced the system functionality. |
FILED | Sunday, March 10, 2013 |
APPL NO | 13/792171 |
ART UNIT | 2128 — AI & Simulation/Modeling |
CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/7 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788540 | Schott et al. |
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FUNDED BY |
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APPLICANT(S) | Brian Schott (Gambrills, Maryland); Robert Parker (Oakton, Virginia) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Brian Schott (Gambrills, Maryland); Robert Parker (Oakton, Virginia) |
ABSTRACT | An API (Application Programming Interface) for an adaptive computing system (ACS) may be used to create a system for performing an application on different types of ACS platforms. The API may be used to generate a system object including a host and a number of nodes and channels. A system data structure is created which describes the nodes, which may be FPGA (Field Programmable Gate Array)-based ACS accelerator boards. The API may enable source-code porting and scaling from small research platforms to larger field-deployable platforms. |
FILED | Tuesday, July 22, 2008 |
APPL NO | 12/177831 |
ART UNIT | 2162 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 9/54 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788701 | Byrnes et al. |
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FUNDED BY |
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APPLICANT(S) | John Byrnes (Poway, California); Richard Rohwer (San Diego, California) |
ASSIGNEE(S) | Fair Isaac Corporation (Minneapolis, Minnesota) |
INVENTOR(S) | John Byrnes (Poway, California); Richard Rohwer (San Diego, California) |
ABSTRACT | The present invention is directed to a method and method which analyzes large amounts of information on a real-time basis with no previous static data set. Attributes of the data, which can be thought of as data concepts, that are present in the data stream are detected and isolated. These concepts are referred to as clusters and are used to ultimately determine the semantics of the data stream. The streaming clusters have no “current membership” in the existing state of the clustering and thus the cluster sets, and their relationship to each other, must be generated and updated as the data is being received. |
FILED | Friday, August 25, 2006 |
APPL NO | 11/509930 |
ART UNIT | 2455 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/238 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788795 | Arimilli et al. |
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FUNDED BY |
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APPLICANT(S) | Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas) |
ABSTRACT | A wake-and-go mechanism may be a programming idiom accelerator. As a processor fetches instructions, the programming idiom accelerator may look ahead to determine whether a programming idiom is coming up in the instruction stream. If the programming idiom accelerator recognizes a programming idiom, the programming idiom accelerator may perform an action to accelerate execution of the programming idiom. In the case of a wake-and-go programming idiom, the programming idiom accelerator may record an entry in a wake-and-go array, for example. |
FILED | Friday, February 01, 2008 |
APPL NO | 12/024364 |
ART UNIT | 2183 — Computer Architecture and I/O |
CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/220 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788884 | Perkins et al. |
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FUNDED BY |
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APPLICANT(S) | Jeff Herbert Perkins (Cambridge, Massachusetts); Stylianos Sidiroglou (Cambridge, Massachusetts); Martin Conway Rinard (Arlington, Massachusetts); Eric Patrick Lahtinen (Canton, Massachusetts); Paolo Mario Piselli (Arlington, Massachusetts); Basil C Krikeles (Wakefield, Massachusetts); Timothy Alan Anderson (Sudbury, Massachusetts); Greg Timothy Sullivan (Auburndale, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Jeff Herbert Perkins (Cambridge, Massachusetts); Stylianos Sidiroglou (Cambridge, Massachusetts); Martin Conway Rinard (Arlington, Massachusetts); Eric Patrick Lahtinen (Canton, Massachusetts); Paolo Mario Piselli (Arlington, Massachusetts); Basil C Krikeles (Wakefield, Massachusetts); Timothy Alan Anderson (Sudbury, Massachusetts); Greg Timothy Sullivan (Auburndale, Massachusetts) |
ABSTRACT | An approach to detection and repair of application level semantic errors in deployed software includes inferring aspects of correct operation of a program. For instance, a suite of examples of operations that are known or assumed to be correct are used to infer correct operation. Further operation of the program can be compared to results found during correct operation and the logic of the program can be augmented to ensure that aspects of further examples of operation of the program are sufficiently similar to the examples in the correct suite. In some examples, the similarity is based on identifying invariants that are satisfied at certain points in the program execution, and augmenting (e.g., “patching”) the logic includes adding tests to confirm that the invariants are satisfied in the new examples. In some examples, the logic invokes an automatic or semi-automatic error handling procedure if the test is not satisfied. Augmenting the logic in this way may prevent malicious parties from exploiting the semantic errors, and may prevent failures in execution of the programs that may have been avoided. |
FILED | Tuesday, December 07, 2010 |
APPL NO | 12/961922 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/38.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08789028 | Shen et al. |
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FUNDED BY |
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APPLICANT(S) | Xiaowei Shen (Hopewell Junction, New York); Peter F. Sweeney (Spring Valley, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Xiaowei Shen (Hopewell Junction, New York); Peter F. Sweeney (Spring Valley, New York) |
ABSTRACT | A computer-implemented method for memory access monitoring, implemented by a managed runtime environment computer system including a controller that monitors application behavior and determines actions to be taken to change a behavior of an application, and a runtime, dynamic compiler that analyzes the application and generates code sequences to access a memory access monitoring (MAM) mechanism, includes determining monitor information of a plurality of fields of a memory block to drive an optimization of the application. |
FILED | Friday, June 30, 2006 |
APPL NO | 11/478743 |
ART UNIT | 2197 — Interprocess Communication and Software Development |
CURRENT CPC | Data processing: Software development, installation, and management 717/151 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08789172 | Stolfo et al. |
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FUNDED BY |
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APPLICANT(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromylis (New York, New York); Elli Androulaki (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromylis (New York, New York); Elli Androulaki (New York, New York) |
ABSTRACT | Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack. In some embodiments, the methods include: selecting a data segment in at least one portion of an electronic document; determining whether the arbitrarily selected data segment can be altered without causing the electronic document to result in an error when processed by a corresponding program; in response to determining that the arbitrarily selected data segment can be altered, arbitrarily altering the data segment in the at least one portion of the electronic document to produce an altered electronic document; and determining whether the corresponding program produces an error state when the altered electronic document is processed by the corresponding program. |
FILED | Wednesday, March 18, 2009 |
APPL NO | 12/406814 |
ART UNIT | 2438 — Cryptography and Security |
CURRENT CPC | Information security 726/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 08783467 | Loutherback et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Kevin Loutherback (Berkeley, California); James C. Sturm (Princeton, New Jersey); Robert Austin (Princeton, New Jersey); Keith Morton (Boucherville, Canada); Jason Puchalla (Princeton, New Jersey) |
ABSTRACT | The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ. |
FILED | Friday, December 07, 2012 |
APPL NO | 13/708425 |
ART UNIT | 3653 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Classifying, separating, and assorting solids 29/210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783866 | Hart et al. |
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FUNDED BY |
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APPLICANT(S) | Robert H. Hart (Cary, North Carolina); Eric L. Buckland (Hickory, North Carolina); Glenn A. Myers (Durham, North Carolina); Joseph A. Izatt (Raleigh, North Carolina) |
ASSIGNEE(S) | Bioptigen, Inc. (Durham, North Carolina) |
INVENTOR(S) | Robert H. Hart (Cary, North Carolina); Eric L. Buckland (Hickory, North Carolina); Glenn A. Myers (Durham, North Carolina); Joseph A. Izatt (Raleigh, North Carolina) |
ABSTRACT | OCT imaging systems are provided for imaging a spherical-type eye including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path. The reference arm path has an associated reference arm path length. A sample is also provided having an associated sample arm path coupled to the source arm and reference arm paths. A lens having a focal power optimized for a diameter of the spherical-type eye is provided along with a reference arm path length adjustment module coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye diameter of the subject. |
FILED | Friday, April 24, 2009 |
APPL NO | 12/429323 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) Original (OR) Class A61B 5/0073 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784502 | Macomber et al. |
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FUNDED BY |
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APPLICANT(S) | Ben Gilbert Macomber (Shoreline, Washington); David Alan Boone (Seattle, Washington) |
ASSIGNEE(S) | Orthocare Innovations LLC (Mountlake Terrace, Washington) |
INVENTOR(S) | Ben Gilbert Macomber (Shoreline, Washington); David Alan Boone (Seattle, Washington) |
ABSTRACT | A computerized prosthesis alignment system includes a transducer that can measure socket reactions in the anterior/posterior plane and the right/left planes, while canceling or reducing the transverse forces on the measurements of these socket reactions. In addition, the transducer is also capable of determining the axial load or weight experienced by the prosthesis. The computerized prosthesis alignment system is in communication with a host computer. The moment data from the transducer is interpreted by the user via a computer interface. The host computer includes memory for storing one or more applications. These applications receive data from the transducer, interpret the data with discrete algebraic or fuzzy logic algorithms, and display the output numerically and graphically. Applications may also interpret the data to provide analysis to the user for aligning the prosthesis. |
FILED | Wednesday, March 16, 2011 |
APPL NO | 13/049593 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Prosthesis 623/39 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784799 | Samulski et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Richard Jude Samulski (Chapel Hill, North Carolina); Douglas M. McCarty (Chapel Hill, North Carolina) |
ABSTRACT | The present invention provides duplexed parvovirus vector genomes that are capable under appropriate conditions of forming a double-stranded molecule by intrastrand base-pairing. Also provided are duplexed parvovirus particles comprising the vector genome. Further disclosed are templates and methods for producing the duplexed vector genomes and duplexed parvovirus particles of the invention. Methods of administering these reagents to a cell or subject are also described. Preferably, the parvovirus capsid is an AAV capsid. It is further preferred that the vector genome comprises AAV terminal repeat sequences. |
FILED | Monday, January 28, 2013 |
APPL NO | 13/751819 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784802 | Sanberg et al. |
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FUNDED BY |
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APPLICANT(S) | Paul R. Sanberg (Spring Hill, Florida); Nelson Americo Hossne, Jr. (São Paulo, Brazil); Alison E. Willing (Tampa, Florida); Adriana Invitti (São Paulo, Brazil) |
ASSIGNEE(S) | Cryopraxis Criobiologia Ltda. (Rio de Janeiro, Brazil); Universidade Federal de Sao Paulo UNIFESP (Sao Paulo, Brazil); University of South Florida (Tampa, Florida) |
INVENTOR(S) | Paul R. Sanberg (Spring Hill, Florida); Nelson Americo Hossne, Jr. (São Paulo, Brazil); Alison E. Willing (Tampa, Florida); Adriana Invitti (São Paulo, Brazil) |
ABSTRACT | The present invention is directed to compositions and methods for treatment of ischemic diseases and conditions, particularly myocardial, CNS/brain and limb ischemia. More particularly, the present invention provides methods of treating disorders by administering monocytes obtained from blood, including umbilical cord blood, peripheral blood, or bone marrow to an individual in need of treatment, wherein the drug is administered to the individual at a time point specifically determined to provide therapeutic efficacy. In one embodiment, the cells are for injection into ischemic myocardium for the treatment of angina. |
FILED | Monday, September 14, 2009 |
APPL NO | 13/063456 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.700 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784807 | Vignali et al. |
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FUNDED BY |
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APPLICANT(S) | Dario Vignali (Germantown, Tennessee); Creg Workman (Memphis, Tennessee); Lauren Collison (Memphis, Tennessee); Kate Vignali (Germantown, Tennessee) |
ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
INVENTOR(S) | Dario Vignali (Germantown, Tennessee); Creg Workman (Memphis, Tennessee); Lauren Collison (Memphis, Tennessee); Kate Vignali (Germantown, Tennessee) |
ABSTRACT | Methods for regulating T cell function in a subject, particularly regulatory T cell activity are provided. Methods of the invention include administering to a subject a therapeutically effective amount of an Interleukin 35-specific binding agent, such as an antibody or small molecule inhibitor. The invention further provides methods for enhancing the immunogenicity of a vaccine or overcoming a suppressed immune response to a vaccine in a subject, including administering to the subject a therapeutically effective amount of an IL35-specific binding agent and administering to the subject a vaccine. In one embodiment the vaccine is a cancer vaccine. |
FILED | Monday, September 24, 2007 |
APPL NO | 12/441166 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784828 | Rikihisa |
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FUNDED BY |
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APPLICANT(S) | Yasuko Rikihisa (Worthington, Ohio) |
ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
INVENTOR(S) | Yasuko Rikihisa (Worthington, Ohio) |
ABSTRACT | The novel omp-1 gene cluster encoding twenty one Ehrlichia ewingii (EE) proteins was isolated and sequenced completely. This invention relates to isolated E. ewingii (EE) polypeptides, isolated polynucleotides encoding EE polypeptides, probes, primers, isolated antibodies and methods of their production, immunogenic compositions and vaccines, as well as methods of using the EE polypeptides, antibodies, probes, and primers for the purpose of diagnosis, therapy and production of vaccines against E. ewingii. |
FILED | Monday, May 05, 2008 |
APPL NO | 12/115490 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/190.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784832 | Adams et al. |
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FUNDED BY |
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APPLICANT(S) | John H. Adams (Tampa, Florida); Francis B. Ntumngia (Tampa, Florida); Jesse L. Schloegel (Five Dock, Australia); Samantha J. Barnes (Tampa, Florida); Amy M. McHenry (Keene, Texas); Patchanee Chootong (Bangkok, Thailand) |
ASSIGNEE(S) | University of South Florida (A Florida Non-Profit Corporation) (Tampa, Florida) |
INVENTOR(S) | John H. Adams (Tampa, Florida); Francis B. Ntumngia (Tampa, Florida); Jesse L. Schloegel (Five Dock, Australia); Samantha J. Barnes (Tampa, Florida); Amy M. McHenry (Keene, Texas); Patchanee Chootong (Bangkok, Thailand) |
ABSTRACT | The disclosure provides compositions that are useful for eliciting a strain-transcending immune response in an animal or human directed against the blood-stage of the malarial parasite Plasmodium vivax. The compositions are based on the ligand domain of Plasmodium vivax Duffy binding protein (PvDBPII). Polar charged polymorphic residues within the dominant strain-specific B-cell epitope were mutated to uncharged residues (e.g. serine, alanine and threonine). This DEKnull variant of PvDBPII produced in bacteria can be purified and refolded in vitro to mimic conformation and erythrocyte binding function of native DBPII. Immunogenicity of DEKnull was confirmed by administration to mice. Compared to the naturally-occurring, strain variant DBPII, DEKnull elicits antibodies that are more broadly reactive with different strain variants of DBPII and enhances production of functional inhibitory antibodies to the shared protective epitopes of native DBPII. |
FILED | Monday, August 20, 2012 |
APPL NO | 13/589253 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/191.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784895 | Messersmith et al. |
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FUNDED BY |
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APPLICANT(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Kvar C. L. Black, IV (Evanston, Illinois); Ji Yi (Evanston, Illinois); Jose G. Rivera (Waukegan, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Kvar C. L. Black, IV (Evanston, Illinois); Ji Yi (Evanston, Illinois); Jose G. Rivera (Waukegan, Illinois) |
ABSTRACT | The present invention provides nanoparticles including a metallic core having a length along each axis of from 1 to 100 nanometers and a coating disposed on at least part of the surface of the metallic core, wherein the coating comprises polydopamine, along with methods for making and using such nanoparticles. The metallic core may be gold, silver or iron oxide and the polydopamine coating may have other substances bound to it, such as silver, targeting ligands or antibodies, or other therapeutic or imaging contrast agents. The disclosed nanoparticles can be targeted to cells for treating cancer or bacterial infections, and for use in diagnostic imaging. |
FILED | Wednesday, March 14, 2012 |
APPL NO | 13/420189 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/491 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785117 | Nyberg |
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FUNDED BY |
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APPLICANT(S) | Scott L Nyberg (Rochester, Minnesota) |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Scott L Nyberg (Rochester, Minnesota) |
ABSTRACT | A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are also described for forming spheroid aggregates from isolated hepatocytes. |
FILED | Tuesday, November 21, 2006 |
APPL NO | 11/562008 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/2 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785119 | Cooperman et al. |
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FUNDED BY |
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APPLICANT(S) | Barry S. Cooperman (Penn Valley, Pennsylvania); Zeev Smilansky (D.N. Emek Sorek, Israel); Yale E. Goldman (Merion, Pennsylvania); Dongli Pan (Brookline, Massachusetts) |
ASSIGNEE(S) | Anima Cell Metrology (Basking Ridge, New Jersey); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Barry S. Cooperman (Penn Valley, Pennsylvania); Zeev Smilansky (D.N. Emek Sorek, Israel); Yale E. Goldman (Merion, Pennsylvania); Dongli Pan (Brookline, Massachusetts) |
ABSTRACT | Provided are methods for labeling transfer RNA comprising replacing the uracil component of a dihydrouridine of said transfer RNA with a fluorophore. The disclosed methods may comprise fluorescent labeling of natural tRNAs (i.e., tRNAs that have been synthesized in a cell, for example, in a bacterium, a yeast cell, or a vertebrate cell) at dihydrouridine (D) positions, or fluorescent labeling of synthetic tRNAs. In another aspect, the present invention provides methods for assessing protein synthesis in a translation system comprise providing a tRNA having a fluorophore substitution for the uracil component of a dihydrouridine in a D loop of the tRNA; introducing the labeled tRNA into the translation system; irradiating the translation system with electromagnetic radiation, thereby generating a fluorescence signal from the fluorophore; detecting the fluorescence signal; and, correlating the fluorescence signal to one or more characteristics of the protein synthesis in the translation system. The disclosed methods are useful in single molecule as well as in ensemble settings. |
FILED | Friday, June 20, 2008 |
APPL NO | 12/664952 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785128 | Hobbs et al. |
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FUNDED BY |
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APPLICANT(S) | Helen H Hobbs (Dallas, Texas); Jonathan C Cohen (Dallas, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Helen H Hobbs (Dallas, Texas); Jonathan C Cohen (Dallas, Texas) |
ABSTRACT | Disclosed are methods of identifying a genetic variant in a person determined to have or be predisposed having a fatty liver by determining whether the person has PNPLA3-I148M. Also disclosed are methods of identifying a genetic variant in a person by determining whether the person has PNPLA3-I148M; and prescribing to the person a treatment to reduce liver fat or associated inflammation. |
FILED | Monday, November 26, 2012 |
APPL NO | 13/684577 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785148 | Sauer-Budge et al. |
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FUNDED BY |
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APPLICANT(S) | Alexis Sauer-Budge (Lincoln, Massachusetts); Andre Sharon (Newton, Massachusetts); Maxim Kalashnikov (Brighton, Massachusetts); Holger Wirz (Medford, Massachusetts) |
ASSIGNEE(S) | Fraunhofer, USA, Inc. (Plymouth, Michigan); Trustees of Boston University (Boston, Massachusetts) |
INVENTOR(S) | Alexis Sauer-Budge (Lincoln, Massachusetts); Andre Sharon (Newton, Massachusetts); Maxim Kalashnikov (Brighton, Massachusetts); Holger Wirz (Medford, Massachusetts) |
ABSTRACT | Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate antibiotics. In another embodiment, the methods and devices described herein are used to determine susceptibility of bacteria to an antibiotic. The methods also provide a method for determining an appropriate antibiotic to treat an individual having a bacterial infection. |
FILED | Friday, October 28, 2011 |
APPL NO | 13/283892 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/32 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785149 | Restifo et al. |
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FUNDED BY |
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APPLICANT(S) | Linda L. Restifo (Tucson, Arizona); Robert Kraft (Tucson, Arizona) |
ASSIGNEE(S) | The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
INVENTOR(S) | Linda L. Restifo (Tucson, Arizona); Robert Kraft (Tucson, Arizona) |
ABSTRACT | The present invention provides neurotoxicity and developmental neurotoxicity screening methods employing primary cultured neurons from Drosophila. |
FILED | Friday, April 08, 2011 |
APPL NO | 13/639541 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/32 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785150 | Taylor et al. |
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FUNDED BY |
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APPLICANT(S) | Clive R. Taylor (South Pasadena, California); Shan Rong Shi (Los Angeles, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Clive R. Taylor (South Pasadena, California); Shan Rong Shi (Los Angeles, California) |
ABSTRACT | Methods for identifying Quantifiable Internal Reference Standards (QIRS) for immunohistochemistry (IHC). Also disclosed are methods for using QIRS to quantify test antigens in IHC. |
FILED | Friday, June 29, 2007 |
APPL NO | 11/772042 |
ART UNIT | 1678 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785157 | Cox et al. |
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FUNDED BY |
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APPLICANT(S) | Michael M. Cox (Oregon, Wisconsin); Marielle C. Eichhorn-Gruenig (Berlin, Germany); James L. Keck (Monona, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Michael M. Cox (Oregon, Wisconsin); Marielle C. Eichhorn-Gruenig (Berlin, Germany); James L. Keck (Monona, Wisconsin) |
ABSTRACT | Kits and a method for cleaving double-stranded DNA using Ref and RecA protein and variants thereof at a site having a DNA sequence homologous to the sequence on a single-stranded DNA targeting fragment are disclosed. |
FILED | Friday, August 12, 2011 |
APPL NO | 13/208985 |
ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/91.530 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785173 | Thompson et al. |
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FUNDED BY |
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APPLICANT(S) | Mark Thompson (Morgan Hill, California); Janice Wee (San Mateo, California); Akanksha Nagpal (San Jose, California) |
ASSIGNEE(S) | MedImmune, LLC (Gaithersburg, Maryland) |
INVENTOR(S) | Mark Thompson (Morgan Hill, California); Janice Wee (San Mateo, California); Akanksha Nagpal (San Jose, California) |
ABSTRACT | The present invention provides methods for the purification of cell-associated viruses from adherent cells (e.g., MDCK or Vero cells). In particular, the present invention provides purification methods for the production of immunogenic compositions comprising a live attenuated cell-associated virus (e.g., an attenuated respiratory syncytial virus (RSV) or cold-adapted, and/or temperature sensitive influenza virus) that result in levels of host cell DNA (HCD), host cell protein (HCP) and non-specific endonuclease (e.g., Benzonase), which are below the specifications required by regulatory agencies. The immunogenic compositions can be used to actively immunize subjects or to generate antibodies for a variety of uses, including passive immunization and diagnostic immunoassays. |
FILED | Thursday, September 24, 2009 |
APPL NO | 13/120638 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/239 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785177 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Min-Feng Yu (Norcross, Georgia); Kyungsuk Yum (Berkeley, California); Ning Wang (Champaign, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois, a body Corporate and Politic of the State of Illinois (Urbana, Illinois) |
INVENTOR(S) | Min-Feng Yu (Norcross, Georgia); Kyungsuk Yum (Berkeley, California); Ning Wang (Champaign, Illinois) |
ABSTRACT | Methods for creating a transient nanoscale opening in a cell membrane and methods for transporting a desired species through the nanoscale opening are provided. A nano-sized needle-like tip can be used to mechanically slice the cell membrane to create a transient, localized nanoscale slit. The nanoscale slit may be used for transferring exogenous molecules into a living cell. |
FILED | Monday, November 05, 2012 |
APPL NO | 13/669233 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/285.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785193 | Shin |
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FUNDED BY |
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APPLICANT(S) | Soojung Shin (Carlsbad, California) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Soojung Shin (Carlsbad, California) |
ABSTRACT | The present disclosure provides cutting tools which include a handle coupled to a rotatable shaft having shallow grooves that extend substantially entirely across the surface of the rotatable shaft. The grooves define sharp cutting edges. In particular examples, the cutting edges are continuous, such as being defined by helical threads. The present disclosure also provides methods of dissecting a substrate of cultured cells. The substrate of cultured cells is separated into separated portions with a cutting tool. The cutting tool includes a rotatable shaft having a cutting blade which extends around the shaft. The cutting blade is rolled through the substrate to cut the substrate into portions. The portions are separated from one another to dissect the substrate. |
FILED | Thursday, September 14, 2006 |
APPL NO | 11/531972 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/378 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785369 | Ford |
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FUNDED BY |
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APPLICANT(S) | Byron D. Ford (Atlanta, Georgia) |
ASSIGNEE(S) | Morehouse School of Medicine (Atlanta, Georgia) |
INVENTOR(S) | Byron D. Ford (Atlanta, Georgia) |
ABSTRACT | Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke or inflammation. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain. |
FILED | Monday, January 26, 2009 |
APPL NO | 12/359773 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/915 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785371 | Patil et al. |
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FUNDED BY |
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APPLICANT(S) | Rameshwar Patil (Los Angeles, California); Eggehard Holler (Los Angeles, California); Keith L. Black (Los Angeles, California); Julia Y. Ljubimova (Studio City, California) |
ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
INVENTOR(S) | Rameshwar Patil (Los Angeles, California); Eggehard Holler (Los Angeles, California); Keith L. Black (Los Angeles, California); Julia Y. Ljubimova (Studio City, California) |
ABSTRACT | The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety. The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety. |
FILED | Friday, December 10, 2010 |
APPL NO | 13/513145 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/1.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785383 | Shi |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Guo-Ping Shi (Newton, Massachusetts) |
ABSTRACT | The present invention is directed to methods of treating or preventing the development of obesity by administering compounds that stabilize mast cells. In addition, it includes pharmaceutical compositions which have both a mast cell stabilizer and instructions regarding the use of the stabilizer in treating or preventing obesity. |
FILED | Monday, April 15, 2013 |
APPL NO | 13/863113 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/8.800 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785385 | Stout et al. |
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FUNDED BY |
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APPLICANT(S) | J. Timothy Stout (Portland, Oregon); Binoy Appukuttan (Portland, Oregon); Trevor McFarland (Portland, Oregon); Anna Dye (Portland, Oregon) |
ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada); Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | J. Timothy Stout (Portland, Oregon); Binoy Appukuttan (Portland, Oregon); Trevor McFarland (Portland, Oregon); Anna Dye (Portland, Oregon) |
ABSTRACT | Disclosed are variant RTEF-1 polypeptides having an RTEF-1 amino acid sequence with one or more internal deletions, wherein the polypeptides reduce VEGF promoter activity. Some of the RTEF-1 polypeptides include an amino acid sequence that is at least 80% identical to the contiguous amino acids of 1) amino acids 24 to 47 of SEQ ID NO:15 and 2) each of SEQ ID NOs:16 and 17, but does not comprise the contiguous amino acids of SEQ ID NOs:8, 9, 11, or 12. Also disclosed are nucleic acids encoding the variant RTEF-1 polypeptides of the present invention. Pharmaceutical compositions that include the polypeptides and nucleic acids of the present invention are also disclosed. Methods of inducing cell contact inhibition, regulating organ size, and reducing intracellular YAP activity are also set forth, as well as methods of treating hyperproliferative diseases such as cancer using the pharmaceutical compositions of the present invention. |
FILED | Tuesday, April 19, 2011 |
APPL NO | 13/089687 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/13.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785395 | Prockop et al. |
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FUNDED BY |
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APPLICANT(S) | Darwin J. Prockop (Philadelphia, Pennsylvania); Joo Youn Oh (Temple, Texas); Gavin W. Roddy (Temple, Texas); Robert Rosa (Holland, Texas); Barry A. Berkowitz (Framingham, Massachusetts) |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Temple Therapeutics, Inc. (Framingham, Massachusetts) |
INVENTOR(S) | Darwin J. Prockop (Philadelphia, Pennsylvania); Joo Youn Oh (Temple, Texas); Gavin W. Roddy (Temple, Texas); Robert Rosa (Holland, Texas); Barry A. Berkowitz (Framingham, Massachusetts) |
ABSTRACT | The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal. |
FILED | Tuesday, May 03, 2011 |
APPL NO | 13/643592 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/20.800 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785411 | Narayan et al. |
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FUNDED BY |
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APPLICANT(S) | Zhenqian Liu (Lenexa, Kansas) |
ASSIGNEE(S) | University of Kansas Medical Center (Kansas City, Kansas) |
INVENTOR(S) | Opendra Narayan (Lenexa, Kansas); Zhenqian Liu (Lenexa, Kansas) |
ABSTRACT | The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of stimulating an immune response against HIV. The DNA molecule is rendered safe for use as a vaccine by the disruption of genes encoding reverse transcriptase, integrase, and Vif. The DNA molecule is further rendered safe by at least a partial deletion of the 3′ LTR. |
FILED | Monday, July 18, 2011 |
APPL NO | 13/185158 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785413 | Blanks et al. |
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FUNDED BY |
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APPLICANT(S) | Janet C. Blanks (Boca Raton, Florida); Howard M. Prentice (Boca Raton, Florida); C. Kathleen Dorey (Roanoke, Virginia) |
ASSIGNEE(S) | Florida Atlantic University Research Corporation (Boca Raton, Florida) |
INVENTOR(S) | Janet C. Blanks (Boca Raton, Florida); Howard M. Prentice (Boca Raton, Florida); C. Kathleen Dorey (Roanoke, Virginia) |
ABSTRACT | The subject invention provides materials and methods useful in safely and effectively preventing pathological proliferation of blood vessels. The prevention of the over-proliferation of blood vessels according to the subject invention is particularly advantageous for treatment of certain ocular conditions including age-related macular degeneration (AMD), retinopathy of prematurity (ROP) and diabetic retinopathy. In preferred embodiments, the subject invention provides materials and methods for effective treatment of pathological ocular neovascularization using gene therapy. In a specific embodiment the materials and methods of the subject invention can be used to treat AMD. |
FILED | Tuesday, September 27, 2011 |
APPL NO | 13/246527 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) C12N 5/0621 (20130101) C12N 15/63 (20130101) Original (OR) Class C12N 2830/002 (20130101) C12N 2830/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785414 | Alevizos et al. |
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FUNDED BY |
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APPLICANT(S) | Ilias Alevizos (Chevy Chase, Maryland); Gabor Illei (Rockville, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Ilias Alevizos (Chevy Chase, Maryland); Gabor Illei (Rockville, Maryland) |
ABSTRACT | The identification of differentially expressed microRNAs in patients with Sjögren's syndrome is disclosed herein. Provided is a method of diagnosing a subject as having Sjögren's syndrome by measuring the level of at least one differentially expressed miR gene product identified herein. An alteration in the level of the at least one miR gene product in the biological sample of the subject relative to a control indicates the subject has Sjögren's syndrome. Also provided is a method of treating a patient with Sjögren's syndrome by administering to the patient a therapeutically effective amount of an agent that inhibits expression of a miR gene product that is up-regulated in the patient with Sjögren's syndrome relative to a control, or by administering to the patient a therapeutically effective amount of an isolated miR gene product that is down-regulated in the patient with Sjögren's syndrome relative to a control. A method of restoring salivary flow in a patient with Sjögren's syndrome is also provided. |
FILED | Wednesday, March 31, 2010 |
APPL NO | 13/262125 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785419 | Murali et al. |
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FUNDED BY |
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APPLICANT(S) | Ramachandran Murali (Swarthmore, Pennsylvania); Mark I. Greene (Penn Valley, Pennsylvania) |
ASSIGNEE(S) | The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Ramachandran Murali (Swarthmore, Pennsylvania); Mark I. Greene (Penn Valley, Pennsylvania) |
ABSTRACT | Method of identifying compounds that modulate intermolecular interactions between a target protein and a modifier are disclosed. Pharmaceutical composition comprising compounds that inhibit intermolecular interactions between a target protein and a modifier are disclosed. Methods of treating individual suffering from inflammatory conditions, undesirable immune responses, immunological conditions and bacterial infections are disclosed. |
FILED | Friday, July 29, 2011 |
APPL NO | 13/194832 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/42 (20130101) A61K 31/17 (20130101) A61K 31/40 (20130101) A61K 31/655 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785423 | Njar et al. |
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FUNDED BY |
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APPLICANT(S) | Vincent Njar (Landsdale, Pennsylvania); Angela Brodie (Fulton, Maryland); Robert Bruno (Columbia, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | Vincent Njar (Landsdale, Pennsylvania); Angela Brodie (Fulton, Maryland); Robert Bruno (Columbia, Maryland) |
ABSTRACT | The present invention provides methods of inducing cell cycle arrest and/or cell growth inhibition, with the methods comprising administering to the cells an effective dose of the compounds of the present invention. |
FILED | Tuesday, April 14, 2009 |
APPL NO | 12/937900 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) Original (OR) Class A61K 31/58 (20130101) A61K 33/24 (20130101) A61K 33/24 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785446 | Jensen et al. |
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FUNDED BY |
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APPLICANT(S) | Frances E. Jensen (Boston, Massachusetts); Sanjay N. Rakhade (Boston, Massachusetts) |
ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
INVENTOR(S) | Frances E. Jensen (Boston, Massachusetts); Sanjay N. Rakhade (Boston, Massachusetts) |
ABSTRACT | Patients are subject to a post-seizure treatment regime to separately inhibitor consecutive targets of an epileptogenic cascade comprising neurotransmitter receptor signaling, kinase/phosphatase activity, protein translation, and apoptosis or inflammation. |
FILED | Sunday, January 17, 2010 |
APPL NO | 12/688892 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) Original (OR) Class A61K 31/366 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785499 | Mackerell, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | Alexander Mackerell, Jr. (Baltimore, Maryland); Hong Zhang (Dallas, Texas); Andrei Osterman (San Diego, California); Rohit Kolhatkar (Loves Park, Illinois) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); The Board of Regents of the University of Texas System (Austin, Texas); Sanford-Burnham Medical Research Institute (La Jolla, California) |
INVENTOR(S) | Alexander Mackerell, Jr. (Baltimore, Maryland); Hong Zhang (Dallas, Texas); Andrei Osterman (San Diego, California); Rohit Kolhatkar (Loves Park, Illinois) |
ABSTRACT | The emergence of multidrug-resistant pathogens necessitates the search for new antibiotics acting on previously unexplored targets. Nicotinate mononucleotide adenylyltransferase of the NadD family, an essential enzyme of NAD biosynthesis in most bacteria, was selected as a target for structure-based inhibitor development. To this end, the inventors have identified small molecule compounds that inhibit bacterial target enzymes by interacting with a novel inhibitory binding site on the enzyme while having no effect on functionally equivalent human enzymes. |
FILED | Monday, July 12, 2010 |
APPL NO | 13/383340 |
ART UNIT | 1672 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/615 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785500 | Charney et al. |
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FUNDED BY |
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APPLICANT(S) | Dennis S. Charney (Chappaqua, New York); Sanjay J. Mathew (New York, New York); Husseini K. Manji (Rockville, Maryland); Carlos A. Zarate, Jr. (Germantown, Maryland); John H. Krystal (Woodbridge, Connecticut) |
ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); Yale University (New Haven, Connecticut); National Institute of Health (Rockville, Maryland) |
INVENTOR(S) | Dennis S. Charney (Chappaqua, New York); Sanjay J. Mathew (New York, New York); Husseini K. Manji (Rockville, Maryland); Carlos A. Zarate, Jr. (Germantown, Maryland); John H. Krystal (Woodbridge, Connecticut) |
ABSTRACT | Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years). |
FILED | Tuesday, March 20, 2007 |
APPL NO | 11/688603 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/647 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785502 | Robertson et al. |
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FUNDED BY |
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APPLICANT(S) | Gavin P. Robertson (Hummelstown, Pennsylvania); Chandagalu D. Raghavendragowda (Hershey, Pennsylvania); SubbaRao V. Madhunapantula (Peddapuram, India); Omer F. Kuzu (Harrisburg, Pennsylvania); Gajanan S. Inamdar (Belgaum, India) |
ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Gavin P. Robertson (Hummelstown, Pennsylvania); Chandagalu D. Raghavendragowda (Hershey, Pennsylvania); SubbaRao V. Madhunapantula (Peddapuram, India); Omer F. Kuzu (Harrisburg, Pennsylvania); Gajanan S. Inamdar (Belgaum, India) |
ABSTRACT | Anti-cancer compositions and methods are described herein. In particular, compositions including one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described. Methods for treatment of pathological conditions particularly cancer, in a subject using one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described herein. |
FILED | Tuesday, December 06, 2011 |
APPL NO | 13/312682 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/655 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785505 | Chen |
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FUNDED BY |
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APPLICANT(S) | Fanqing Chen (Moraga, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Fanqing Chen (Moraga, California) |
ABSTRACT | The increasing use of nanotechnology in consumer products and medical applications underlies the importance of understanding its potential toxic effects to people and the environment. Herein are described methods and assays to predict and evaluate the cellular effects of nanomaterial exposure. Exposing cells to nanomaterials at cytotoxic doses induces cell cycle arrest and increases apoptosis/necrosis, activates genes involved in cellular transport, metabolism, cell cycle regulation, and stress response. Certain nanomaterials induce genes indicative of a strong immune and inflammatory response within skin fibroblasts. Furthermore, the described multiwall carbon nanoonions (MWCNOs) can be used as a therapeutic in the treatment of cancer due to its cytotoxicity. |
FILED | Monday, April 28, 2008 |
APPL NO | 12/111026 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785514 | Rawls et al. |
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FUNDED BY |
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APPLICANT(S) | H. Ralph Rawls (San Antonio, Texas); Kyumin Whang (San Antonio, Texas); Nasser Barghi (San Antonio, Texas); Dong-Hoon Shin (Cheonan, South Korea); Richard Plymale (Davison, Michigan); Janice Plymale (Davison, Michigan) |
ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | H. Ralph Rawls (San Antonio, Texas); Kyumin Whang (San Antonio, Texas); Nasser Barghi (San Antonio, Texas); Dong-Hoon Shin (Cheonan, South Korea); Richard Plymale (Davison, Michigan) |
ABSTRACT | Various embodiments of the present invention generally relate to a light-cure and dual-cure resin that have low color and is color stable over conventional light, self and dual-cured resins. Additionally, the light-cure resin has enhanced degree of cure over conventional light-cure resins. Finally, due to the low color and enhanced color stability of the dual-cure resins, their inherent property of having lower shrinkage stress as compared to light-cure resins can now be utilized in various dental applications and other resin applications. |
FILED | Friday, November 28, 2008 |
APPL NO | 12/745423 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Synthetic resins or natural rubbers 522/15 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785601 | Rosenberg et al. |
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FUNDED BY |
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APPLICANT(S) | Steven A. Rosenberg (Potomac, Maryland); Richard A. Morgan (Columbia, Maryland); Timothy L. Frankel (New York, New York); Peter Peng (Baltimore, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Steven A. Rosenberg (Potomac, Maryland); Richard A. Morgan (Columbia, Maryland); Timothy L. Frankel (New York, New York); Peter Peng (Baltimore, Maryland) |
ABSTRACT | The invention provides T cell receptors (TCRs) having antigenic specificity for a cancer antigen, e.g., tyrosinase. Also provided are related polypeptides, proteins, nucleic acids, recombinant expression vectors, isolated host cells, populations of cells, and pharmaceutical compositions. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host using the inventive TCRs or related materials. |
FILED | Monday, January 25, 2010 |
APPL NO | 13/146531 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785602 | Braun et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jonathan Braun (Tarzana, California); Lynn K. Gordon (Tarzana, California); Kaori Shimazaki Dadgostar (Los Angeles, California); Madhuri Wadehra (Manhattan Beach, California); Kathleen A. Kelly (Pacific Palisades, California); Anna M. Wu (Sherman Oaks, California) |
ABSTRACT | The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The methods and compositions target cancers which express or overexpress EMP2 nucleic acids and polypeptides by targeting EMP2. |
FILED | Monday, October 28, 2013 |
APPL NO | 14/064956 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785609 | Chang et al. |
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FUNDED BY |
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APPLICANT(S) | Nancy T. Chang (Houston, Texas); Robert C. Gallo (Bethesda, Maryland); Flossie Wong-Staal (Germantown, Maryland) |
ASSIGNEE(S) | United States of America as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Nancy T. Chang (Houston, Texas); Robert C. Gallo (Bethesda, Maryland); Flossie Wong-Staal (Germantown, Maryland) |
ABSTRACT | The determination of the nucleotide sequence of HTLV-III DNA; identification, isolation and expression of HTLV-III sequences which encode immunoreactive polypeptides by recombinant DNA methods and production of viral RNA are disclosed. Such polypeptides can be employed in immunoassays to detect HTLV-III. |
FILED | Monday, June 05, 1995 |
APPL NO | 08/462504 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/702 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785618 | Lieberman et al. |
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FUNDED BY |
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APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
INVENTOR(S) | Judy Lieberman (Brookline, Massachusetts); Erwei Song (Guangdong, China PRC) |
ABSTRACT | The invention provides a method of RNA interference, which comprises contacting the cell with a fusion protein-double stranded RNA complex, the complex comprising the double stranded RNA segment containing a double stranded RNA of interest and a fusion protein, the fusion protein comprising (1) a targeting moiety, which will specifically binds to a site on a target cell, and (2) a binding moiety, which will bind to the double stranded RNA, wherein the double stranded RNA segment initiates RNA interference in the cell. |
FILED | Tuesday, July 23, 2013 |
APPL NO | 13/948435 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/24.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785682 | FitzGerald et al. |
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FUNDED BY |
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APPLICANT(S) | Garret A. FitzGerald (Wayne, Pennsylvania); Wenliang Song (Philadelphia, Pennsylvania); John A. Lawson (Penn Valley, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Garret A. FitzGerald (Wayne, Pennsylvania); Wenliang Song (Philadelphia, Pennsylvania); John A. Lawson (Penn Valley, Pennsylvania) |
ABSTRACT | The present invention relates to a prostaglandin D2 metabolite, derivatives thereof, compositions comprising the metabolite, and an antibody that specially binds to the metabolite. Methods of use are also provided. |
FILED | Monday, September 29, 2008 |
APPL NO | 12/680153 |
ART UNIT | 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 59/11 (20130101) C07C 61/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/567 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785718 | Fahrenkrug et al. |
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FUNDED BY |
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APPLICANT(S) | Recombinetics, Inc. (Saint Paul, Minnesota) |
ASSIGNEE(S) | Recombinetics, Inc. (Saint Paul, Minnesota) |
INVENTOR(S) | Scott C. Fahrenkrug (Minneapolis, Minnesota); Daniel F. Carlson (Inver Grove Heights, Minnesota); Aron M. Geurts (New Berlin, Wisconsin) |
ABSTRACT | Methods of using hypermethylated transposons to create genetically modified animals that express interfering RNAs are described. |
FILED | Friday, October 05, 2012 |
APPL NO | 13/645788 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8509 (20130101) C12N 2800/90 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08787411 | Wise et al. |
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FUNDED BY |
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APPLICANT(S) | Frank Wise (Ithaca, New York); William Renninger (Ithaca, New York); Andy Chong (Dayton, Ohio) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Frank Wise (Ithaca, New York); William Renninger (Ithaca, New York); Andy Chong (Dayton, Ohio) |
ABSTRACT | Implementations and examples of mode-locked fiber lasers based on fiber laser cavity designs that produce self-similar pulses (“similaritons”) with parabolic pulse profiles with respect to time at the output of the fiber gain media to effectuate the desired mode locking operation. An intra-cavity narrowband optical spectral filter is included in such fiber lasers to ensure the proper similariton conditions. |
FILED | Thursday, June 21, 2012 |
APPL NO | 13/530044 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788004 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Bo Chen (Derby, Connecticut); Paul B. Benni (Stamford, Connecticut) |
ASSIGNEE(S) | CAS Medical Systems, Inc. (Branford, Connecticut) |
INVENTOR(S) | Bo Chen (Derby, Connecticut); Paul B. Benni (Stamford, Connecticut) |
ABSTRACT | A method and apparatus for non-invasively determining the blood oxygenation within a subject's tissue is provided that utilizes a near infrared spectrophotometric (NIRS) sensor capable of transmitting a light signal into the tissue of a subject and sensing the light signal once it has passed through the tissue via transmittance or reflectance. |
FILED | Monday, December 12, 2011 |
APPL NO | 13/323479 |
ART UNIT | 3777 — Optical Communications |
CURRENT CPC | Surgery 6/323 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788013 | Silber |
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FUNDED BY |
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APPLICANT(S) | Harry A. Silber (Owings Mills, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Harry A. Silber (Owings Mills, Maryland) |
ABSTRACT | Featured are methods for non-invasive assessment of vascular reactivity. The methods of the invention use phase contrast magnetic resonance imaging angiography and use the image data thereby acquired to measure shear rate, radius of the vasculature and flow through the vasculature. According to one aspect, such acquisition of image data occurs before and during, an arterial occlusion and according to another aspect such acquisition of image data occurs before during and after arterial occlusion. The disclosed methods of the invention allow for reproducible, non-invasive diagnosis of early stage indicators of atherosclerosis. |
FILED | Thursday, January 19, 2006 |
APPL NO | 11/795784 |
ART UNIT | 3777 — Optical Communications |
CURRENT CPC | Surgery 6/410 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788017 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Xinsheng Cedric Yu (Clarksville, Maryland); Ying Su Yu (Clarksville, Maryland); William Regine (Cockeysville, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); Xcision Medical Systems, LLC (Clarksville, Maryland) |
INVENTOR(S) | Xinsheng Cedric Yu (Clarksville, Maryland); Ying Su Yu (Clarksville, Maryland); William Regine (Cockeysville, Maryland) |
ABSTRACT | A method of treating a cancerous region in a breast of a patient comprising (i) imaging the breast in a three-dimensional coordinate system, (ii) stereotactically determining the location of the cancerous region in the breast, (iii) optionally determining the volume of the entire cancerous region to be treated, and (iv) while maintaining the breast in a three-dimensional coordinate system that is identical to or corresponds with the three-dimensional coordinate system used in (i), noninvasively exposing the cancerous region of the breast of the patient to a cancer-treatment effective dose of radiation; and equipment for use in such a method. |
FILED | Tuesday, February 26, 2008 |
APPL NO | 12/449827 |
ART UNIT | 3777 — Optical Communications |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/00 (20130101) Original (OR) Class A61B 6/02 (20130101) A61B 6/022 (20130101) A61B 6/0435 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 08783106 | Nielson et al. |
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FUNDED BY |
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APPLICANT(S) | Gregory N. Nielson (Albuquerque, New Mexico); Eric Langlois (Albuquerque, New Mexico); Michael Baker (Albuquerque, New Mexico); Murat Okandan (Edgewood, New Mexico); Robert Anderson (Tucson, Arizona) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Gregory N. Nielson (Albuquerque, New Mexico); Eric Langlois (Albuquerque, New Mexico); Michael Baker (Albuquerque, New Mexico); Murat Okandan (Edgewood, New Mexico); Robert Anderson (Tucson, Arizona) |
ABSTRACT | An accelerometer includes a proof mass and a frame that are formed in a handle layer of a silicon-on-an-insulator (SOI). The proof mass is separated from the frame by a back-side trench that defines a boundary of the proof mass. The accelerometer also includes a reflector coupled to a top surface of the proof mass. An optical detector is located above the reflector at the device side. The accelerometer further includes at least one suspension spring. The suspension spring has a handle anchor that extends downwards from the device side to the handle layer to mechanically support upward and downward movement of the proof mass relative to a top surface of the proof mass. |
FILED | Tuesday, December 13, 2011 |
APPL NO | 13/324012 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/514.260 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783109 | Kaduchak et al. |
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FUNDED BY |
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APPLICANT(S) | Gregory Kaduchak (Los Alamos, New Mexico); Greg Goddard (Los Alamos, New Mexico); Gary Salzman (White Rock, New Mexico); Dipen Sinha (Los Alamos, New Mexico); John C. Martin (Los Alamos, New Mexico); Christopher Kwiatkowski (Los Alamos, New Mexico); Steven Graves (San Juan Pueblo, New Mexico) |
ASSIGNEE(S) | Los Alamos National Sercurity, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Gregory Kaduchak (Los Alamos, New Mexico); Greg Goddard (Los Alamos, New Mexico); Gary Salzman (White Rock, New Mexico); Dipen Sinha (Los Alamos, New Mexico); John C. Martin (Los Alamos, New Mexico); Christopher Kwiatkowski (Los Alamos, New Mexico); Steven Graves (San Juan Pueblo, New Mexico) |
ABSTRACT | The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid. |
FILED | Wednesday, October 31, 2007 |
APPL NO | 11/982042 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/570.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783371 | Blount et al. |
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FUNDED BY |
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APPLICANT(S) | Gerald Blount (North Augusta, South Carolina); Alvin A. Siddal (Aiken, South Carolina); Ronald W. Falta (Seneca, South Carolina) |
ASSIGNEE(S) | |
INVENTOR(S) | Gerald Blount (North Augusta, South Carolina); Alvin A. Siddal (Aiken, South Carolina); Ronald W. Falta (Seneca, South Carolina) |
ABSTRACT | A process and apparatus of separating CO2 gas from industrial off-gas source in which the CO2 containing off-gas is introduced deep within an injection well. The CO2 gases are dissolved in the, liquid within the injection well while non-CO2 gases, typically being insoluble in water or brine, are returned to the surface. Once the CO2 saturated liquid is present within the injection well, the injection well may be used for long-term geologic storage of CO2 or the CO2 saturated liquid can be returned to the surface for capturing a purified CO2 gas. |
FILED | Thursday, January 07, 2010 |
APPL NO | 12/655789 |
ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Wells 166/402 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784052 | Shi et al. |
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FUNDED BY |
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APPLICANT(S) | Jun Shi (Glastonbury, Connecticut); Kevin E. Green (Broad Brook, Connecticut) |
ASSIGNEE(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
INVENTOR(S) | Jun Shi (Glastonbury, Connecticut); Kevin E. Green (Broad Brook, Connecticut) |
ABSTRACT | An example gas turbine engine shroud includes a first annular ceramic wall having an inner side for resisting high temperature turbine engine gasses and an outer side with a plurality of radial slots. A second annular metallic wall is positioned radially outwardly of and enclosing the first annular ceramic wall and has a plurality of tabs in communication with the slot of the first annular ceramic wall. The tabs of the second annular metallic wall and slots of the first annular ceramic wall are in communication such that the first annular ceramic wall and second annular metallic wall are affixed. |
FILED | Monday, May 10, 2010 |
APPL NO | 12/776673 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Rotary kinetic fluid motors or pumps 415/197 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784536 | Ryan et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanstone, Illinois) |
INVENTOR(S) | Patrick J. Ryan (Vernon Hills, Illinois); Omar K. Farha (Morton Grove, Illinois); Linda J. Broadbelt (Glenview, Illinois); Randall Q. Snurr (Evanston, Illinois); Youn-Sang Bae (Evanston, Illinois) |
ABSTRACT | Metal-organic framework (MOF) materials are provided and are selectively adsorbent to xenon (Xe) over another noble gas such as krypton (Kr) and/or argon (Ar) as a result of having framework voids (pores) sized to this end. MOF materials having pores that are capable of accommodating a Xe atom but have a small enough pore size to receive no more than one Xe atom are desired to preferentially adsorb Xe over Kr in a multi-component (Xe—Kr mixture) adsorption method. The MOF material has 20% or more, preferably 40% or more, of the total pore volume in a pore size range of 0.45-0.75 nm which can selectively adsorb Xe over Kr in a multi-component Xe—Kr mixture over a pressure range of 0.01 to 1.0 MPa. |
FILED | Friday, August 23, 2013 |
APPL NO | 13/974406 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/127 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784657 | Cho et al. |
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FUNDED BY |
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APPLICANT(S) | Young I. Cho (Cherry Hill, New Jersey); Alexander Fridman (Marlton, New Jersey); Alexander F. Gutsol (San Ramon, California); Yong Yang (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Young I. Cho (Cherry Hill, New Jersey); Alexander Fridman (Marlton, New Jersey); Alexander F. Gutsol (San Ramon, California); Yong Yang (Philadelphia, Pennsylvania) |
ABSTRACT | The present invention is directed to a novel method for cleaning a filter surface using a plasma discharge self-cleaning filtration system. The method involves utilizing plasma discharges to induce short electric pulses of nanoseconds duration at high voltages. These electrical pulses generate strong Shockwaves that disintegrate and dislodge particulate matter located on the surface of the filter. |
FILED | Thursday, August 07, 2008 |
APPL NO | 12/672005 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Liquid purification or separation 210/269 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784698 | Schreuder et al. |
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FUNDED BY |
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APPLICANT(S) | Michael A. Schreuder (Burnsville, Minnesota); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Michael A. Schreuder (Burnsville, Minnesota); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ABSTRACT | Disclosed are inorganic nanoparticles comprising a body comprising cadmium and/or zinc crystallized with selenium, sulfur, and/or tellurium; a multiplicity of phosphonic acid ligands comprising at least about 20% of the total surface ligand coverage; wherein the nanocrystal is capable of absorbing energy from a first electromagnetic region and capable of emitting light in a second electromagnetic region, wherein the maximum absorbance wavelength of the first electromagnetic region is different from the maximum emission wavelength of the second electromagnetic region, thereby providing a Stokes shift of at least about 20 nm, wherein the second electromagnetic region comprises an at least about 100 nm wide band of wavelengths, and wherein the nanoparticle exhibits has a quantum yield of at least about 10%. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
FILED | Tuesday, May 24, 2011 |
APPL NO | 13/115001 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/64 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/04 (20130101) C09C 1/10 (20130101) C09C 1/12 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) Original (OR) Class C09K 11/025 (20130101) C09K 11/565 (20130101) C09K 11/883 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784703 | Kahen et al. |
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FUNDED BY |
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APPLICANT(S) | Keith Brian Kahen (Rochester, New York); Matthew Holland (Victor, New York); Sudeep Pallikkara Kuttiatoor (Rochester, New York) |
ASSIGNEE(S) | Eastman Kodak Company (Rochester, New York) |
INVENTOR(S) | Keith Brian Kahen (Rochester, New York); Matthew Holland (Victor, New York); Sudeep Pallikkara Kuttiatoor (Rochester, New York) |
ABSTRACT | A method of making a colloidal solution of high confinement semiconductor nanocrystals includes: forming a first solution by combining a solvent, growth ligands, and at most one semiconductor precursor; heating the first solution to the nucleation temperature; and adding to the first solution, a second solution having a solvent, growth ligands, and at least one additional and different precursor than that in the first solution to form a crude solution of nanocrystals having a compact homogenous semiconductor region. The method further includes: waiting 0.5 to 20 seconds and adding to the crude solution a third solution having a solvent, growth ligands, and at least one additional and different precursor than those in the first and second solutions; and lowering the growth temperature to enable the formation of a gradient alloy region around the compact homogenous semiconductor region, resulting in the formation of a colloidal solution of high confinement semiconductor nanocrystals. |
FILED | Tuesday, October 18, 2011 |
APPL NO | 13/275595 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Compositions 252/519.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784866 | Tour et al. |
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FUNDED BY |
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APPLICANT(S) | James M. Tour (Bellaire, Texas); Rebecca Lucente-Schultz (Houston, Texas); Ashley Leonard (Houston, Texas); Dmitry V. Kosynkin (Houston, Texas); Brandi Katherine Price (Houston, Texas); Jared L. Hudson (Hamilton, Virginia); Jodie L. Conyers, Jr. (Houston, Texas); Valerie C. Moore (Houston, Texas); S. Ward Casscells (Houston, Texas); Jeffrey N. Myers (Houston, Texas); Zvonimir L. Milas (Houston, Texas); Kathy A. Mason (Houston, Texas); Luka Milas (Houston, Texas) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | James M. Tour (Bellaire, Texas); Rebecca Lucente-Schultz (Houston, Texas); Ashley Leonard (Houston, Texas); Dmitry V. Kosynkin (Houston, Texas); Brandi Katherine Price (Houston, Texas); Jared L. Hudson (Hamilton, Virginia); Jodie L. Conyers, Jr. (Houston, Texas); Valerie C. Moore (Houston, Texas); S. Ward Casscells (Houston, Texas); Jeffrey N. Myers (Houston, Texas); Zvonimir L. Milas (Houston, Texas); Kathy A. Mason (Houston, Texas); Luka Milas (Houston, Texas) |
ABSTRACT | Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described. |
FILED | Friday, October 03, 2008 |
APPL NO | 12/245438 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/424 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785023 | Horne et al. |
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FUNDED BY |
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APPLICANT(S) | Craig R. Horne (Sunnyvale, California); Kim Kinoshita (Cupertino, California); Darren B. Hickey (Santa Clara, California); Jay E. Sha (Mountain View, California); Deepak Bose (Fremont, California) |
ASSIGNEE(S) | Enervault Corparation (Sunnyvale, California) |
INVENTOR(S) | Craig R. Horne (Sunnyvale, California); Kim Kinoshita (Cupertino, California); Darren B. Hickey (Santa Clara, California); Jay E. Sha (Mountain View, California); Deepak Bose (Fremont, California) |
ABSTRACT | A reduction/oxidation (“redox”) flow battery system includes a series of electrochemical cells arranged in a cascade, whereby liquid electrolyte reacts in a first electrochemical cell (or group of cells) before being directed into a second cell (or group of cells) where it reacts before being directed to subsequent cells. The cascade includes 2 to n stages, each stage having one or more electrochemical cells. During a charge reaction, electrolyte entering a first stage will have a lower state-of-charge than electrolyte entering the nth stage. In some embodiments, cell components and/or characteristics may be configured based on a state-of-charge of electrolytes expected at each cascade stage. Such engineered cascades provide redox flow battery systems with higher energy efficiency over a broader range of current density than prior art arrangements. |
FILED | Friday, January 07, 2011 |
APPL NO | 12/986892 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/1824 (20130101) B60L 11/1879 (20130101) B60L 2210/40 (20130101) B60L 2230/22 (20130101) B60L 2230/24 (20130101) B60L 2230/28 (20130101) B60L 2230/30 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/40 (20130101) H01M 6/188 (20130101) H01M 8/20 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/705 (20130101) Y02T 10/7005 (20130101) Y02T 10/7088 (20130101) Y02T 10/7241 (20130101) Y02T 90/12 (20130101) Y02T 90/14 (20130101) Y02T 90/127 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785123 | Xu et al. |
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FUNDED BY |
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APPLICANT(S) | Ting Xu (Berkeley, California); Yue Zhao (Mountain View, California); Kari Thorkelsson (Berkeley, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Ting Xu (Berkeley, California); Yue Zhao (Mountain View, California); Kari Thorkelsson (Berkeley, California) |
ABSTRACT | The present invention provides hierarchical assemblies of a block copolymer, a bifunctional linking compound and a nanoparticle. The block copolymers form one micro-domain and the nanoparticles another micro-domain. |
FILED | Monday, October 18, 2010 |
APPL NO | 13/502362 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785159 | Linger et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey G. Linger (Dever, Colorado); Aldis Darzins (Highlands Ranch, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Jeffrey G. Linger (Dever, Colorado); Aldis Darzins (Highlands Ranch, Colorado) |
ABSTRACT | Nucleic acids encoding secretion signals, expression vectors containing the nucleic acids, and host cells containing the expression vectors are disclosed. Also disclosed are polypeptides that contain the secretion signals and methods of producing polypeptides, including methods of directing the extracellular secretion of the polypeptides. Exemplary embodiments include cellulase proteins fused to secretion signals, methods to produce and isolate these polypeptides, and methods to degrade lignocellulosic biomass. |
FILED | Friday, November 19, 2010 |
APPL NO | 12/950442 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/99 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785226 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Seung Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
ABSTRACT | Exemplary embodiments provide semiconductor nanowires and nanowire devices/applications and methods for their formation. In embodiments, in-plane nanowires can be epitaxially grown on a patterned substrate, which are more favorable than vertical ones for device processing and three-dimensional (3D) integrated circuits. In embodiments, the in-plane nanowire can be formed by selective epitaxy utilizing lateral overgrowth and faceting of an epilayer initially grown in a one-dimensional (1D) nanoscale opening. In embodiments, optical, electrical, and thermal connections can be established and controlled between the nanowire, the substrate, and additional electrical or optical components for better device and system performance. |
FILED | Friday, September 20, 2013 |
APPL NO | 14/032904 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/34 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785236 | Harley et al. |
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FUNDED BY |
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APPLICANT(S) | SunPower Corporation (San Jose, California) |
ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
INVENTOR(S) | Gabriel Harley (Mountain View, California); David D. Smith (Campbell, California); Peter John Cousins (Menlo Park, California) |
ABSTRACT | The formation of solar cell contacts using a laser is described. A method of fabricating a back-contact solar cell includes forming a poly-crystalline material layer above a single-crystalline substrate. The method also includes forming a dielectric material stack above the poly-crystalline material layer. The method also includes forming, by laser ablation, a plurality of contacts holes in the dielectric material stack, each of the contact holes exposing a portion of the poly-crystalline materiat layer; and forming conductive contacts in the plurality of contact holes. |
FILED | Monday, November 05, 2012 |
APPL NO | 13/669147 |
ART UNIT | 2823 — Semiconductors/Memory |
CURRENT CPC | Semiconductor device manufacturing: Process 438/98 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785346 | Biener et al. |
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FUNDED BY |
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APPLICANT(S) | Juergen Biener (San Leandro, California); Alex V. Hamza (Livermore, California); Marcus Baeumer (Bremen, Germany); Christian Schulz (Bremen, Germany); Birte Jürgens (Lilienthal, Germany); Monika M. Biener (San Leandro, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Universitaet Bremen (Bremen, Germany); Monika M. Biener (San Leandro, California) |
INVENTOR(S) | Juergen Biener (San Leandro, California); Alex V. Hamza (Livermore, California); Marcus Baeumer (Bremen, Germany); Christian Schulz (Bremen, Germany); Birte Jürgens (Lilienthal, Germany); Monika M. Biener (San Leandro, California) |
ABSTRACT | A method for forming a gold-containing catalyst with porous structure according to one embodiment of the present invention includes producing a starting alloy by melting together of gold and at least one less noble metal that is selected from the group consisting of silver, copper, rhodium, palladium, and platinum; and a dealloying step comprising at least partial removal of the less noble metal by dissolving the at least one less noble metal out of the starting alloy. Additional methods and products thereof are also presented. |
FILED | Monday, June 08, 2009 |
APPL NO | 12/480545 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/52 (20130101) Original (OR) Class B01J 23/56 (20130101) B01J 25/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) H01M 4/98 (20130101) H01M 2008/1095 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785505 | Chen |
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FUNDED BY |
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APPLICANT(S) | Fanqing Chen (Moraga, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Fanqing Chen (Moraga, California) |
ABSTRACT | The increasing use of nanotechnology in consumer products and medical applications underlies the importance of understanding its potential toxic effects to people and the environment. Herein are described methods and assays to predict and evaluate the cellular effects of nanomaterial exposure. Exposing cells to nanomaterials at cytotoxic doses induces cell cycle arrest and increases apoptosis/necrosis, activates genes involved in cellular transport, metabolism, cell cycle regulation, and stress response. Certain nanomaterials induce genes indicative of a strong immune and inflammatory response within skin fibroblasts. Furthermore, the described multiwall carbon nanoonions (MWCNOs) can be used as a therapeutic in the treatment of cancer due to its cytotoxicity. |
FILED | Monday, April 28, 2008 |
APPL NO | 12/111026 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785905 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | George T. Wang (Albuquerque, New Mexico); Qiming Li (Albuquerque, New Mexico); Jonathan J. Wierer, Jr. (Albuquerque, New Mexico); Daniel Koleske (Albuquerque, New Mexico) |
ABSTRACT | A temperature stable (color and efficiency) III-nitride based amber (585 nm) light-emitting diode is based on a novel hybrid nanowire-planar structure. The arrays of GaN nanowires enable radial InGaN/GaN quantum well LED structures with high indium content and high material quality. The high efficiency and temperature stable direct yellow and red phosphor-free emitters enable high efficiency white LEDs based on the RGYB color-mixing approach. |
FILED | Thursday, January 17, 2013 |
APPL NO | 13/743438 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/04 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/762 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786179 | Thompson et al. |
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FUNDED BY |
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APPLICANT(S) | Universal Display Corporation (Ewing, New Jersey) |
ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey) |
INVENTOR(S) | Mark E. Thompson (Anaheim, California); P. Daniel Dapkus (Fullerton, California) |
ABSTRACT | The present invention relates to phosphors for energy downconversion of high energy light to generate a broadband light spectrum, which emit light of different emission wavelengths. |
FILED | Monday, September 17, 2012 |
APPL NO | 13/621739 |
ART UNIT | 2879 — Optics |
CURRENT CPC | Electric lamp and discharge devices 313/504 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786249 | Koritarov |
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FUNDED BY |
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APPLICANT(S) | Vladimir Koritarov (Naperville, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Vladimir Koritarov (Naperville, Illinois) |
ABSTRACT | Frequency responsive charging for plug-in hybrid electric vehicles (PHEV) and battery electric vehicles (BEV), a frequency sensing charging system and a method are provided for implementing demand response and regulation services to power grid using frequency detection for a frequency-based charge controller for plug-in hybrid electric vehicles (PHEV) and battery electric vehicles (BEV). A frequency of the power grid is continuously monitored and compared to a predefined tolerance band by a frequency sensor. Responsive to the frequency being outside the predefined tolerance band, the frequency is applied to a programmable logic controller. The programmable logic controller uses the applied frequency to identify a control action. A charge controller and a switch coupled to a battery charger receive respective identified control actions for controlling the battery charger. |
FILED | Friday, August 05, 2011 |
APPL NO | 13/204092 |
ART UNIT | 2859 — Printing/Measuring and Testing |
CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/1816 (20130101) B60L 11/1838 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/04 (20130101) Original (OR) Class H02J 7/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786327 | Honea et al. |
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FUNDED BY |
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APPLICANT(S) | James Honea (Santa Barbara, California); Yifeng Wu (Goleta, California) |
ASSIGNEE(S) | Transphorm Inc. (Goleta, California) |
INVENTOR(S) | James Honea (Santa Barbara, California); Yifeng Wu (Goleta, California) |
ABSTRACT | An electronic component comprising a half bridge adapted for operation with an electrical load having an operating frequency is described. The half bridge comprises a first switch and a second switch each having a switching frequency, the first switch and the second switch each including a first terminal, a second terminal, and a control terminal, wherein the first terminal of the first switch and the second terminal of the second switch are both electrically connected to a node. The electronic component further includes a filter having a 3 dB roll-off frequency, the 3 dB roll-off frequency being less than the switching frequency of the switches but greater than the operating frequency of the electrical load. The first terminal of the filter is electrically coupled to the node, and the 3 dB roll-off frequency of the filter is greater than 5 kHz. |
FILED | Thursday, February 23, 2012 |
APPL NO | 13/403813 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/110 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786840 | Woodruff et al. |
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FUNDED BY |
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APPLICANT(S) | Steven D. Woodruff (Morgantown, West Virginia); Dustin L. Mcintyre (Washington, Pennsylvania); Jinesh C. Jain (Southpark, Pennsylvania) |
ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
INVENTOR(S) | Steven D. Woodruff (Morgantown, West Virginia); Dustin L. Mcintyre (Washington, Pennsylvania); Jinesh C. Jain (Southpark, Pennsylvania) |
ABSTRACT | A method and device for remotely monitoring an area using a low peak power optical pump comprising one or more pumping sources, one or more lasers; and an optical response analyzer. Each pumping source creates a pumping energy. The lasers each comprise a high reflectivity mirror, a laser media, an output coupler, and an output lens. Each laser media is made of a material that emits a lasing power when exposed to pumping energy. Each laser media is optically connected to and positioned between a corresponding high reflectivity mirror and output coupler along a pumping axis. Each output coupler is optically connected to a corresponding output lens along the pumping axis. The high reflectivity mirror of each laser is optically connected to an optical pumping source from the one or more optical pumping sources via an optical connection comprising one or more first optical fibers. |
FILED | Thursday, January 26, 2012 |
APPL NO | 13/358853 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/72 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786852 | Bond et al. |
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FUNDED BY |
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APPLICANT(S) | Tiziana C. Bond (Livermore, California); Robin Miles (Danville, California); James C. Davidson (Livermore, California); Gang Logan Liu (Champaign, Illinois) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
INVENTOR(S) | Tiziana C. Bond (Livermore, California); Robin Miles (Danville, California); James C. Davidson (Livermore, California); Gang Logan Liu (Champaign, Illinois) |
ABSTRACT | Methods for fabricating nanoscale array structures suitable for surface enhanced Raman scattering, structures thus obtained, and methods to characterize the nanoscale array structures suitable for surface enhanced Raman scattering. Nanoscale array structures may comprise nanotrees, nanorecesses and tapered nanopillars. |
FILED | Wednesday, December 01, 2010 |
APPL NO | 12/957883 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Optics: Measuring and testing 356/301 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788415 | Chassin et al. |
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FUNDED BY |
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APPLICANT(S) | David P. Chassin (Pasco, Washington); Robert G. Pratt (Kennewick, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | David P. Chassin (Pasco, Washington); Robert G. Pratt (Kennewick, Washington) |
ABSTRACT | Disclosed herein are representative embodiments of methods, apparatus, and systems for distributing a resource (such as electricity) using a resource allocation system. In one exemplary embodiment, a plurality of requests for electricity are received from a plurality of end-use consumers. The requests indicate a requested quantity of electricity and a consumer-requested index value indicative of a maximum price a respective end-use consumer will pay for the requested quantity of electricity. A plurality of offers for supplying electricity are received from a plurality of resource suppliers. The offers indicate an offered quantity of electricity and a supplier-requested index value indicative of a minimum price for which a respective supplier will produce the offered quantity of electricity. A dispatched index value is computed at which electricity is to be supplied based at least in part on the consumer-requested index values and the supplier-requested index values. |
FILED | Tuesday, September 29, 2009 |
APPL NO | 12/587006 |
ART UNIT | 3693 — Business Methods - Finance/Banking/ Insurance |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/102 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788649 | Faraj |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Daniel A. Faraj (Rochester, Minnesota) |
ABSTRACT | Constructing a logical regular topology from an irregular topology including, for each axial dimension and recursively, for each compute node in a subcommunicator until returning to a first node: adding to a logical line of the axial dimension a neighbor specified in a nearest neighbor list; calling the added compute node; determining, by the called node, whether any neighbor in the node's nearest neighbor list is available to add to the logical line; if a neighbor in the called compute node's nearest neighbor list is available to add to the logical line, adding, by the called compute node to the logical line, any neighbor in the called compute node's nearest neighbor list for the axial dimension not already added to the logical line; and, if no neighbor in the called compute node's nearest neighbor list is available to add to the logical line, returning to the calling compute node. |
FILED | Wednesday, January 16, 2013 |
APPL NO | 13/742453 |
ART UNIT | 2441 — Computer Networks |
CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/223 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788879 | Blumrich et al. |
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FUNDED BY |
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APPLICANT(S) | Matthias A. Blumrich (Yorktown Heights, New York); Dong Chen (Yorktown Heights, New York); Thomas M. Cipolla (Yorktown Heights, New York); Paul W. Coteus (Yorktown Heights, New York); Alan Gara (Yorktown Heights, New York); Philip Heidelberger (Yorktown Heights, New York); Mark J. Jeanson (Rochester, Minnesota); Gerard V. Kopcsay (Yorktown Heights, New York); Martin Ohmacht (Yorktown Heights, New York); Todd E. Takken (Yorktown Heights, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Matthias A. Blumrich (Yorktown Heights, New York); Dong Chen (Yorktown Heights, New York); Thomas M. Cipolla (Yorktown Heights, New York); Paul W. Coteus (Yorktown Heights, New York); Alan Gara (Yorktown Heights, New York); Philip Heidelberger (Yorktown Heights, New York); Mark J. Jeanson (Rochester, Minnesota); Gerard V. Kopcsay (Yorktown Heights, New York); Martin Ohmacht (Yorktown Heights, New York); Todd E. Takken (Yorktown Heights, New York) |
ABSTRACT | A system, method and computer program product for supporting system initiated checkpoints in high performance parallel computing systems and storing of checkpoint data to a non-volatile memory storage device. The system and method generates selective control signals to perform checkpointing of system related data in presence of messaging activity associated with a user application running at the node. The checkpointing is initiated by the system such that checkpoint data of a plurality of network nodes may be obtained even in the presence of user applications running on highly parallel computers that include ongoing user messaging activity. In one embodiment, the non-volatile memory is a pluggable flash memory card. |
FILED | Monday, January 10, 2011 |
APPL NO | 13/004005 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Error detection/correction and fault detection/recovery 714/13 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08789025 | O'Brien et al. |
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FUNDED BY |
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APPLICANT(S) | John K. P. O'Brien (South Salem, New York); Kai-Ting Amy Wang (North York, Canada); Mark Yamashita (Toronto, Canada); Xiaotong Zhuang (White Plains, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | John K. P. O'Brien (South Salem, New York); Kai-Ting Amy Wang (North York, Canada); Mark Yamashita (Toronto, Canada); Xiaotong Zhuang (White Plains, New York) |
ABSTRACT | A mechanism is provided for path-sensitive analysis for reducing rollback overheads. The mechanism receives, in a compiler, program code to be compiled to form compiled code. The mechanism divides the code into basic blocks. The mechanism then determines a restore register set for each of the one or more basic blocks to form one or more restore register sets. The mechanism then stores the one or more register sets such that responsive to a rollback during execution of the compiled code. A rollback routine identifies a restore register set from the one or more restore register sets and restores registers identified in the identified restore register set. |
FILED | Wednesday, July 14, 2010 |
APPL NO | 12/835820 |
ART UNIT | 2192 — Interprocess Communication and Software Development |
CURRENT CPC | Data processing: Software development, installation, and management 717/140 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08789067 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporations (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Kristan D. Davis (Rochester, Minnesota); Daniel A. Faraj (Rochester, Minnesota) |
ABSTRACT | Algorithm selection for data communications in a parallel active messaging interface (‘PAMI’) of a parallel computer, the PAMI composed of data communications endpoints, each endpoint including specifications of a client, a context, and a task, endpoints coupled for data communications through the PAMI, including associating in the PAMI data communications algorithms and ranges of message sizes so that each algorithm is associated with a separate range of message sizes; receiving in an origin endpoint of the PAMI a data communications instruction, the instruction specifying transmission of a data communications message from the origin endpoint to a target endpoint, the data communications message characterized by a message size; selecting, from among the associated algorithms and ranges, a data communications algorithm in dependence upon the message size; and transmitting, according to the selected data communications algorithm from the origin endpoint to the target endpoint, the data communications message. |
FILED | Wednesday, October 24, 2012 |
APPL NO | 13/659370 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/313 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08789172 | Stolfo et al. |
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FUNDED BY |
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APPLICANT(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromylis (New York, New York); Elli Androulaki (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromylis (New York, New York); Elli Androulaki (New York, New York) |
ABSTRACT | Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack. In some embodiments, the methods include: selecting a data segment in at least one portion of an electronic document; determining whether the arbitrarily selected data segment can be altered without causing the electronic document to result in an error when processed by a corresponding program; in response to determining that the arbitrarily selected data segment can be altered, arbitrarily altering the data segment in the at least one portion of the electronic document to produce an altered electronic document; and determining whether the corresponding program produces an error state when the altered electronic document is processed by the corresponding program. |
FILED | Wednesday, March 18, 2009 |
APPL NO | 12/406814 |
ART UNIT | 2438 — Cryptography and Security |
CURRENT CPC | Information security 726/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08789211 | Passian et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (OakRidge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Ali Passian (Knoxville, Tennessee); Thomas George Thundat (Knoxville, Tennessee); Laurene Tetard (Knoxville, Tennessee) |
ABSTRACT | A method of analyzing a sample that includes applying a first set of energies at a first set of frequencies to a sample and applying, simultaneously with the applying the first set of energies, a second set of energies at a second set of frequencies, wherein the first set of energies and the second set of energies form a multi-mode coupling. The method further includes detecting an effect of the multi-mode coupling. |
FILED | Monday, May 20, 2013 |
APPL NO | 13/897857 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/36 (20130101) Original (OR) Class G01Q 90/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 08783466 | Han et al. |
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FUNDED BY |
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APPLICANT(S) | Jongyoon Han (Bedford, Massachusetts); Jianping Fu (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Jongyoon Han (Bedford, Massachusetts); Jianping Fu (Cambridge, Massachusetts) |
ABSTRACT | This invention provides a method and an apparatus for quickly continuously fractionating biomolecules, such as DNAs, proteins and carbohydrates by taking advantage of differential bidirectional transport of biomolecules with varying physico-chemical characteristics, for example size, charge, hydrophobicity, or combinations thereof, through periodic arrays of microfabricated nanofilters. The passage of biomolecules through the nanofilter is a function of both steric and electrostatic interactions between charged macromolecules and charged nanofilter walls, Continuous-flow separation through the devices of this invention are applicable for molecules varying in terms of any molecular properties (e.g., size, charge density or hydrophobicity) that can lead to differential transport across the nanofilters. |
FILED | Thursday, January 13, 2011 |
APPL NO | 13/005840 |
ART UNIT | 3653 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Separation B01D 61/027 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/0864 (20130101) B01L 2300/0896 (20130101) B01L 2400/086 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2015/0288 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08783467 | Loutherback et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Kevin Loutherback (Berkeley, California); James C. Sturm (Princeton, New Jersey); Robert Austin (Princeton, New Jersey); Keith Morton (Boucherville, Canada); Jason Puchalla (Princeton, New Jersey) |
ABSTRACT | The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ. |
FILED | Friday, December 07, 2012 |
APPL NO | 13/708425 |
ART UNIT | 3653 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Classifying, separating, and assorting solids 29/210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784673 | Xiong et al. |
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FUNDED BY |
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APPLICANT(S) | Xugang Xiong (Boston, Massachusetts); Laila Jaberansari (Medford, Massachusetts); Ahmed Busnaina (Ashland, Massachusetts); Yung Joon Jung (Lexington, Massachusetts); Sivasubramanian Somu (Boston, Massachusetts); Moneesh Upmanyu (Wakefield, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Xugang Xiong (Boston, Massachusetts); Laila Jaberansari (Medford, Massachusetts); Ahmed Busnaina (Ashland, Massachusetts); Yung Joon Jung (Lexington, Massachusetts); Sivasubramanian Somu (Boston, Massachusetts); Moneesh Upmanyu (Wakefield, Massachusetts) |
ABSTRACT | Methods for fabricating templates for nanoelement assembly and methods for fluid-guided assembly of nanoelements are provided. Templates are fabricated by plasma modification of surface hydrophilicity and production of a network of hydrophobic trenches having a hydrophilic bottom surface. Single-walled carbon nanotubes (SWNT) can be assembled into stable films, ribbons, and wires of nanoscale thickness and nanoscale or microscale width and length. The nanofilm assemblies prepared according to the invention are highly conductive and can be used in the fabrication of a wide variety of microscale and nanoscale electronic devices. |
FILED | Monday, November 16, 2009 |
APPL NO | 12/619187 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Etching a substrate: Processes 216/17 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784698 | Schreuder et al. |
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FUNDED BY |
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APPLICANT(S) | Michael A. Schreuder (Burnsville, Minnesota); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Michael A. Schreuder (Burnsville, Minnesota); James R. McBride (Nashville, Tennessee); Sandra J. Rosenthal (Nashville, Tennessee) |
ABSTRACT | Disclosed are inorganic nanoparticles comprising a body comprising cadmium and/or zinc crystallized with selenium, sulfur, and/or tellurium; a multiplicity of phosphonic acid ligands comprising at least about 20% of the total surface ligand coverage; wherein the nanocrystal is capable of absorbing energy from a first electromagnetic region and capable of emitting light in a second electromagnetic region, wherein the maximum absorbance wavelength of the first electromagnetic region is different from the maximum emission wavelength of the second electromagnetic region, thereby providing a Stokes shift of at least about 20 nm, wherein the second electromagnetic region comprises an at least about 100 nm wide band of wavelengths, and wherein the nanoparticle exhibits has a quantum yield of at least about 10%. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
FILED | Tuesday, May 24, 2011 |
APPL NO | 13/115001 |
ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/64 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/04 (20130101) C09C 1/10 (20130101) C09C 1/12 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) Original (OR) Class C09K 11/025 (20130101) C09K 11/565 (20130101) C09K 11/883 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784766 | Uppireddi et al. |
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FUNDED BY |
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APPLICANT(S) | Kishore Uppireddi (San Juan, Puerto Rico); Gerardo Morell (Guaynabo, Puerto Rico); Brad R. Weiner (Dorado, Puerto Rico) |
ASSIGNEE(S) | The University of Puerto Rico (San Juan, Puerto Rico) |
INVENTOR(S) | Kishore Uppireddi (San Juan, Puerto Rico); Gerardo Morell (Guaynabo, Puerto Rico); Brad R. Weiner (Dorado, Puerto Rico) |
ABSTRACT | Iron nanoparticles were employed to induce the synthesis of diamond on molybdenum, silicon, and quartz substrates. Diamond films were grown using conventional conditions for diamond synthesis by hot filament chemical vapor deposition, except that dispersed iron oxide nanoparticles replaced the seeding. This approach to diamond induction can be combined with dip pen nanolithography for the selective deposition of diamond and diamond patterning while avoiding surface damage associated to diamond-seeding methods. |
FILED | Monday, January 18, 2010 |
APPL NO | 12/689180 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/446 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785174 | Ruiz |
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FUNDED BY |
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APPLICANT(S) | Oscar N. Ruiz (Toa Alta, Puerto Rico) |
ASSIGNEE(S) | Inter American University of Puerto Rico (San Juan, Puerto Rico) |
INVENTOR(S) | Oscar N. Ruiz (Toa Alta, Puerto Rico) |
ABSTRACT | The invention provides a system of heavy metal sequestration by bacteria. The bacteria expresses the ppk, mt, and/or β-galactosidase (lacZ) genes and can tolerate at least 25 μM mercury, 1,000 μM zinc, 250 μM cadmium, and 3,000 μM Pb. The system allows for facile determination of the presence of heavy metal contaminants in a liquid and the facile collection of the bacteria that has sequestered large amounts of heavy metal. Further provided is a system of gene expression in bacteria that comprises phage and plastid gene expression elements and delivers a particularly high level of protein expression and heavy metal resistance. |
FILED | Thursday, August 19, 2010 |
APPL NO | 12/859590 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/341 (20130101) C02F 2101/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/70 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) G01N 33/523 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785177 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Min-Feng Yu (Norcross, Georgia); Kyungsuk Yum (Berkeley, California); Ning Wang (Champaign, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois, a body Corporate and Politic of the State of Illinois (Urbana, Illinois) |
INVENTOR(S) | Min-Feng Yu (Norcross, Georgia); Kyungsuk Yum (Berkeley, California); Ning Wang (Champaign, Illinois) |
ABSTRACT | Methods for creating a transient nanoscale opening in a cell membrane and methods for transporting a desired species through the nanoscale opening are provided. A nano-sized needle-like tip can be used to mechanically slice the cell membrane to create a transient, localized nanoscale slit. The nanoscale slit may be used for transferring exogenous molecules into a living cell. |
FILED | Monday, November 05, 2012 |
APPL NO | 13/669233 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/285.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785369 | Ford |
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FUNDED BY |
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APPLICANT(S) | Byron D. Ford (Atlanta, Georgia) |
ASSIGNEE(S) | Morehouse School of Medicine (Atlanta, Georgia) |
INVENTOR(S) | Byron D. Ford (Atlanta, Georgia) |
ABSTRACT | Neuregulin, a known neuroprotein, has been found to ameliorate or prevent damage caused by mechanical or chemical assault to blood vessels and, when administered into the cerebral spinal fluid, can ameliorate damage to neuronal tissue caused by stroke or inflammation. Additionally, neuregulin has been found to be useful for enhancement of stem cell migration from the ventricle to the site of injury to the brain. |
FILED | Monday, January 26, 2009 |
APPL NO | 12/359773 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/915 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785763 | LeMieux et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Melburne C. LeMieux (La Honda, California); Ajay Virkar (Stanford, California); Zhenan Bao (Stanford, California) |
ABSTRACT | Nanostructures are joined using one or more of a variety of materials and approaches. As consistent with various example embodiments, two or more nanostructures are joined at a junction between the nanostructures. The nanostructures may touch or be nearly touching at the junction, and a joining material is deposited and nucleates at the junction to couple the nanostructures together. In various applications, the nucleated joining material facilitates conductivity (thermal and/or electric) between the nanostructures. In some embodiments, the joining material further enhances conductivity of the nanostructures themselves, such as by growing along the nanostructures and/or doping the nanostructures. |
FILED | Friday, August 30, 2013 |
APPL NO | 14/015192 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/244 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785846 | Ouyang et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); Chen Tsung-Chi (West Lafayette, Indiana) |
ABSTRACT | The invention generally relates to systems and methods for sample analysis. In certain embodiments, the invention provides systems for analyzing a sample that include an electric source, a vacuum chamber including a conducting member, in which the conducting member is coupled to the electric source, a sample introduction member coupled to the vacuum chamber, and a mass analyzer. The system is configured such that a distal end of the sample introduction member resides within the vacuum chamber and proximate the conducting member, such that an electrical discharge may be produced between the sample introduction member and the conducting member. A neutral gas that has been introduced into the vacuum chamber interacts with the generated discharge, producing ions within the vacuum chamber that are subsequently transferred into the mass analyzer in the vacuum chamber. |
FILED | Monday, October 21, 2013 |
APPL NO | 14/058856 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/26 (20130101) H01J 49/0495 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785881 | Lozano et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Paulo C. Lozano (Arlington, Massachusetts); Steven Mark Arestie (Boston, Massachusetts) |
ABSTRACT | An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or room-temperature molten salt. The body can have a pore size gradient that decreases from the base of the body to the tip of the body, such that the at least one of an ionic liquid or room-temperature molten salt is capable of being transported through capillarity from the base to the tip. |
FILED | Friday, November 01, 2013 |
APPL NO | 14/070351 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/02 (20130101) Original (OR) Class H01J 37/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08787411 | Wise et al. |
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FUNDED BY |
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APPLICANT(S) | Frank Wise (Ithaca, New York); William Renninger (Ithaca, New York); Andy Chong (Dayton, Ohio) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Frank Wise (Ithaca, New York); William Renninger (Ithaca, New York); Andy Chong (Dayton, Ohio) |
ABSTRACT | Implementations and examples of mode-locked fiber lasers based on fiber laser cavity designs that produce self-similar pulses (“similaritons”) with parabolic pulse profiles with respect to time at the output of the fiber gain media to effectuate the desired mode locking operation. An intra-cavity narrowband optical spectral filter is included in such fiber lasers to ensure the proper similariton conditions. |
FILED | Thursday, June 21, 2012 |
APPL NO | 13/530044 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/6 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08787529 | Graves et al. |
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FUNDED BY |
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APPLICANT(S) | William S. Graves (Marblehead, Massachusetts); Franz X. Kaertner (Newton, Massachusetts); David E. Moncton (Newton, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | William S. Graves (Marblehead, Massachusetts); Franz X. Kaertner (Newton, Massachusetts); David E. Moncton (Newton, Massachusetts) |
ABSTRACT | Coherent electronic current, which can be used to generate coherent radiation, is generated by first generating and transmitting an array of discrete electron beamlets from a nanocathode array along a longitudinal axis. The array of electron beamlets is then focused to reduce the spacing that separates the electron beamlets. The transverse-axis spacing of the electron beamlets is then transferred to the longitudinal axis via an emittance exchange beamline, creating a periodically modulated distribution of coherent electronic current. The coherent electronic current can then be directed into a stream of photons to generate coherent radiation. |
FILED | Wednesday, May 11, 2011 |
APPL NO | 13/105114 |
ART UNIT | 2882 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 35/02 (20130101) H01J 2235/068 (20130101) X-ray Technique H05G 2/00 (20130101) Original (OR) Class H05G 2/008 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 2007/005 (20130101) H05H 2007/007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788021 | Flusberg et al. |
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FUNDED BY |
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APPLICANT(S) | Benjamin A. Flusberg (Stanford, California); Eric David Cocker (Menlo Park, California); Juergen Claus Jung (Palo Alto, California); Mark Jacob Schnitzer (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior Univerity (Palo Alto, California) |
INVENTOR(S) | Benjamin A. Flusberg (Stanford, California); Eric David Cocker (Menlo Park, California); Juergen Claus Jung (Palo Alto, California); Mark Jacob Schnitzer (Palo Alto, California) |
ABSTRACT | Analysis of live beings is facilitated. According to an example embodiment of the present invention, a light-directing arrangement such as an endoscope is mounted to a live being. Optics in the light-directing arrangement are implemented to pass source light (e.g., laser excitation light) into the live being, and to pass light from the live being for detection thereof. The light from the live being may include, for example, photons emitted in response to the laser excitation light (i.e., fluoresced). The detected light is then used to detect a characteristic of the live being. |
FILED | Tuesday, January 24, 2006 |
APPL NO | 11/338598 |
ART UNIT | 3768 — Optical Communications |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0013 (20130101) A61B 5/0059 (20130101) Original (OR) Class A61B 5/0062 (20130101) A61B 5/0068 (20130101) A61B 5/0071 (20130101) A61B 5/0075 (20130101) A61B 5/4064 (20130101) A61B 5/6814 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) G01J 3/4406 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788277 | Vezyrtzis et al. |
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FUNDED BY |
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APPLICANT(S) | Christos Vezyrtzis (New York, New York); Aaron Klein (Flushing, New York); Yannis Tsividis (New York, New York); Daniel P. W. Ellis (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Christos Vezyrtzis (New York, New York); Aaron Klein (Flushing, New York); Yannis Tsividis (New York, New York); Daniel P. W. Ellis (New York, New York) |
ABSTRACT | Apparatus and methods for processing compression encoded signals are provided. In some embodiments, a signal processing method is provided that includes receiving a subband of a compression encoded signal at a subband processor, generating envelope information regarding the subband of the compression encoded signal to provide changes in the dynamic range of the compression encoded signal for fixed-point digital signal processing, processing the compression encoded signal with a fixed-point companding digital signal processor using the envelope information, and producing a processed compression encoded signal at the output of the subband processor. |
FILED | Monday, September 13, 2010 |
APPL NO | 12/880858 |
ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/500 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 08784838 | Olsen et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Christopher W. Olsen (Madison, Wisconsin); Gabriele A. Landolt (Fort Collins, Colorado); Alexander I. Karasin (Madison, Wisconsin) |
ABSTRACT | The invention provides an isolated H3 equine influenza A virus, as well as methods of preparing and using the virus, and genes or proteins thereof. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/839111 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/209.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784842 | Davis et al. |
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FUNDED BY |
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APPLICANT(S) | William C. Davis (Pullman, Washington); Mary Jo Hamilton (Moscow, Idaho); John Dahl (Pullman, Washington); Kun Taek Park (Pullman, Washington) |
ASSIGNEE(S) | Washington State University (Pullman, Washington) |
INVENTOR(S) | William C. Davis (Pullman, Washington); Mary Jo Hamilton (Moscow, Idaho); John Dahl (Pullman, Washington); Kun Taek Park (Pullman, Washington) |
ABSTRACT | Particular aspects provide efficient allelic exchange methods to generate directed mutations within genes of slow-growing stains of mycobacteria (e.g., Mycobacterium avium subsp. paratuberculosis (Map), Map 10 or GFP-expressing Map K-10) using a phage-delivery system, and demonstrate high efficiency allelic exchange. Additional exemplary aspects provide non-naturally occurring slow-growing strains of mycobacteria (e.g., Map, M. bovis, M. tuberculosis) having at least one gene deletion (e.g., pknG, relA, lsr2, panC, panD, proC, trpD, sapM (MAP3432), lysA_1, leuD, and leuC, and deletion mutants at the orthologous loci of two known virulence genes in pathogenic mycobacteria (relA and pknG) and one gene related to colony morphology and biofilm formation in fast growing mycobacteria (lsr2) were made. Further aspects provide novel vaccines comprising such deletion mutants, or portions thereof, and methods for making said vaccines. Yet further aspects provide methods for protecting a mammal from virulent Map, M. bovis, or M. tuberculosis, comprising treating the mammal with the inventive vaccines. |
FILED | Monday, July 14, 2008 |
APPL NO | 12/668651 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/248.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784856 | Stevens et al. |
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FUNDED BY |
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APPLICANT(S) | Jan F. Stevens (Corvallis, Oregon); Stephen Machado (Pendelton, Oregon); Ralph Reed (Philomath, Oregon); Michael S. Martinez (Salem, Oregon) |
ASSIGNEE(S) | The State of Oregon Acting by and Through the State Boad of Higher Education on Behalf of Oregon State University (Corvallis, Oregon) |
INVENTOR(S) | Jan F. Stevens (Corvallis, Oregon); Stephen Machado (Pendelton, Oregon); Ralph Reed (Philomath, Oregon); Michael S. Martinez (Salem, Oregon) |
ABSTRACT | Particular aspects provide methods for converting glucosinolate in a glucosinolate-containing plant material to glucosinolate breakdown products (GBPs), comprising: providing an amount of processed glucosinolate-containing plant material, the processed material being depleted of oil and glucosinolate converting enzyme activity by virtue of said processing; providing an amount of glucosinolate converting enzyme activity; mixing the processed material with the amount enzyme activity; hydrating the mixture; and incubating the hydrated mixture, wherein the glucosinolates are enzymatically converted to GBPs. Preferably, the processed plant material comprises a oilseed-derived seedmeal material (e.g., meadowfoam seedmeal) from which the oil has been removed by the processing (e.g., solvent extraction and/or heat treatment). In particular embodiments, the glucosinolate converting enzyme activity comprises at least one of a myrosinase activity and a nitrile-forming activity. Additional aspects provide low-fat compositions (e.g., herbicide, fungicide, insecticide, bacteriostatic or bactericidal, cosmetic, cosmeceutical or pharmaceutical) comprising GBPs derived from a glucosinolate-containing plant material. |
FILED | Monday, July 21, 2008 |
APPL NO | 12/664984 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) A01N 25/32 (20130101) Original (OR) Class A01N 65/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785421 | Lippolis et al. |
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FUNDED BY |
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APPLICANT(S) | John D. Lippolis (Ames, Iowa); Timothy A. Reinhardt (Ames, Iowa) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | John D. Lippolis (Ames, Iowa); Timothy A. Reinhardt (Ames, Iowa) |
ABSTRACT | Hydroxylated derivatives of vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol) are effective for preventing or treating mastitis in animals. The hydroxylated derivatives of vitamins D3 or D2 are administered to the mammary gland of a female animal in an amount effective to inhibit or significantly reduce the growth of bacteria in the animal's mammary gland. |
FILED | Friday, March 30, 2012 |
APPL NO | 13/434985 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/165 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08787633 | Robinson et al. |
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FUNDED BY |
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APPLICANT(S) | J. Paul Robinson (West Lafayette, Indiana); Bartlomiej Rajwa (West Lafayette, Indiana); Bulent Bayraktar (West Lafayette, Indiana); Arun K. Bhunia (West Lafayette, Indiana); E. Daniel Hirleman (West Lafayette, Indiana); Euiwon Bae (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | J. Paul Robinson (West Lafayette, Indiana); Bartlomiej Rajwa (West Lafayette, Indiana); Bulent Bayraktar (West Lafayette, Indiana); Arun K. Bhunia (West Lafayette, Indiana); E. Daniel Hirleman (West Lafayette, Indiana); Euiwon Bae (West Lafayette, Indiana) |
ABSTRACT | A system and method for identifying organisms by analysis of scattergrams of colonies is disclosed. cattergrams are obtained by culturing samples and illuminating the resultant colonies by a laser. The forward scattered light is imaged and subject to a feature extraction process. The feature vector may include Zernike or Chebyshev moments and may also include Harelick texture features. Feature vectors may be used to train a classification process using either supervised or unsupervised machine learning techniques. The classification process may be used to associate a colony phenotype with the genotype of the sample. |
FILED | Friday, January 11, 2008 |
APPL NO | 12/008476 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Image analysis 382/128 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP24680 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
ASSIGNEE(S) | Florida Foundation Seed Producers, Inc. (Marianna, Florida) |
INVENTOR(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
ABSTRACT | A new and distinct cultivar of caladium plant named ‘UF 44-4’, characterized by its compact growth habit, plants with numerous lance-type leaves that are slightly undulate, leaves that have bright red center and green margins, and plants that are attractive in containers or landscapes. |
FILED | Friday, August 24, 2012 |
APPL NO | 13/573133 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP24681 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
ASSIGNEE(S) | Florida Foundation Speed Producers, Inc. (Marianna, Florida) |
INVENTOR(S) | Zhanao Deng (Riverview, Florida); Brent K. Harbaugh (Bradenton, Florida) |
ABSTRACT | A new and distinct cultivar of Caladium plant named ‘UF-85-5’ is disclosed. ‘UF-85-5’ is characterized by its fancy leaves with a white/green leaf face and red spots, and it has been demonstrated to sprout early, produce attractive pot plants when tubers are forced in containers, and it possess exceptional sunburn tolerance. |
FILED | Friday, August 10, 2012 |
APPL NO | 13/507998 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/373 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 08783026 | Floyd |
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FUNDED BY |
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APPLICANT(S) | Brian A. Floyd (Madison, Alabama) |
ASSIGNEE(S) | |
INVENTOR(S) | Brian A. Floyd (Madison, Alabama) |
ABSTRACT | A staged rocket apparatus includes first and second stages connected by a releasable connector. A plurality of pressurized gas struts are connected between the first and second stages and provide a separating force urging the first and second stages apart. The gas struts are held in a telescopingly collapsed first position by the releasable connector. The separating force is maintained at a minimum value so long as the releasable connector holds the struts in their first position. When the releasable connector is disconnected the separating force increases due to gas flow through a metering passage having a progressively increasing flow area from a high pressure chamber to a low pressure chamber. |
FILED | Saturday, December 10, 2011 |
APPL NO | 13/316477 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 15/36 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784766 | Uppireddi et al. |
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FUNDED BY |
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APPLICANT(S) | Kishore Uppireddi (San Juan, Puerto Rico); Gerardo Morell (Guaynabo, Puerto Rico); Brad R. Weiner (Dorado, Puerto Rico) |
ASSIGNEE(S) | The University of Puerto Rico (San Juan, Puerto Rico) |
INVENTOR(S) | Kishore Uppireddi (San Juan, Puerto Rico); Gerardo Morell (Guaynabo, Puerto Rico); Brad R. Weiner (Dorado, Puerto Rico) |
ABSTRACT | Iron nanoparticles were employed to induce the synthesis of diamond on molybdenum, silicon, and quartz substrates. Diamond films were grown using conventional conditions for diamond synthesis by hot filament chemical vapor deposition, except that dispersed iron oxide nanoparticles replaced the seeding. This approach to diamond induction can be combined with dip pen nanolithography for the selective deposition of diamond and diamond patterning while avoiding surface damage associated to diamond-seeding methods. |
FILED | Monday, January 18, 2010 |
APPL NO | 12/689180 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/446 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784866 | Tour et al. |
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FUNDED BY |
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APPLICANT(S) | James M. Tour (Bellaire, Texas); Rebecca Lucente-Schultz (Houston, Texas); Ashley Leonard (Houston, Texas); Dmitry V. Kosynkin (Houston, Texas); Brandi Katherine Price (Houston, Texas); Jared L. Hudson (Hamilton, Virginia); Jodie L. Conyers, Jr. (Houston, Texas); Valerie C. Moore (Houston, Texas); S. Ward Casscells (Houston, Texas); Jeffrey N. Myers (Houston, Texas); Zvonimir L. Milas (Houston, Texas); Kathy A. Mason (Houston, Texas); Luka Milas (Houston, Texas) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | James M. Tour (Bellaire, Texas); Rebecca Lucente-Schultz (Houston, Texas); Ashley Leonard (Houston, Texas); Dmitry V. Kosynkin (Houston, Texas); Brandi Katherine Price (Houston, Texas); Jared L. Hudson (Hamilton, Virginia); Jodie L. Conyers, Jr. (Houston, Texas); Valerie C. Moore (Houston, Texas); S. Ward Casscells (Houston, Texas); Jeffrey N. Myers (Houston, Texas); Zvonimir L. Milas (Houston, Texas); Kathy A. Mason (Houston, Texas); Luka Milas (Houston, Texas) |
ABSTRACT | Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described. |
FILED | Friday, October 03, 2008 |
APPL NO | 12/245438 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/424 |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 08783467 | Loutherback et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
INVENTOR(S) | Kevin Loutherback (Berkeley, California); James C. Sturm (Princeton, New Jersey); Robert Austin (Princeton, New Jersey); Keith Morton (Boucherville, Canada); Jason Puchalla (Princeton, New Jersey) |
ABSTRACT | The disclosure relates to obstacle array devices (also known as bump array devices) for separating populations of particles by size. Improvements over previous obstacle array devices are realized by causing the fluid velocity profile across gaps between obstacles to be asymmetrical with respect to the plane that bisects the gap and is parallel to the direction of bulk fluid flow. Such asymmetry can be achieved by selecting the shape(s) of the obstacles bounding the gap such that the portions of the obstacles upstream from, downstream from or bridging the narrowest portion of the gap are asymmetrical with respect to that plane. Improvements are also realized by using obstacles that have sharp edges bounding the gaps. Other improvements are realized by selecting obstacle shapes such that the critical particle dimensions defined by the gaps in two different fluid flow directions differ. |
FILED | Friday, December 07, 2012 |
APPL NO | 13/708425 |
ART UNIT | 3653 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Classifying, separating, and assorting solids 29/210 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08784293 | Berka et al. |
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FUNDED BY |
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APPLICANT(S) | Advanced Brain Monitoring, Inc. (Carlsbad, California) |
ASSIGNEE(S) | Advanced Brain Monitoring, Inc. (Carlsbad, California) |
INVENTOR(S) | Christine Berka (Carlsbad, California); Djordje Popovic (Carlsbad, California); Dan Levendowski (Carlsbad, California); Gene Davis (Carlsbad, California); Catherine McConnell (Carlsbad, California); Matthew A. Yanagi (Carlsbad, California) |
ABSTRACT | Systems and methods for optimizing sleep and post-sleep performance. In an embodiment, a system comprising a device and sleep mask are provided. The mask may comprise electroencephalographic (EEG) sensors and one or more stimulation elements configured to stimulate the senses of a wearer of the mask. The mask may be releasably and electrically coupled to a device which receives EEG signals from the mask, determines current and target sleep states based, at least in part, on the EEG signals, and uses this determination to tailor a sleep architecture of the wearer by controlling the stimulation elements. The mask may be a soft mask which utilizes conductive thread embroidered into one or more textile layers. In an embodiment, the stimulation elements may comprise one or more heating elements, electroluminescent panels, and speakers. In addition, the EEG sensors may comprise hybrid sensors comprising hydrogel in a conductive spacer fabric. |
FILED | Wednesday, June 05, 2013 |
APPL NO | 13/910709 |
ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) Original (OR) Class A61M 21/02 (20130101) A61M 230/10 (20130101) A61M 2021/0027 (20130101) A61M 2230/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08788017 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Xinsheng Cedric Yu (Clarksville, Maryland); Ying Su Yu (Clarksville, Maryland); William Regine (Cockeysville, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); Xcision Medical Systems, LLC (Clarksville, Maryland) |
INVENTOR(S) | Xinsheng Cedric Yu (Clarksville, Maryland); Ying Su Yu (Clarksville, Maryland); William Regine (Cockeysville, Maryland) |
ABSTRACT | A method of treating a cancerous region in a breast of a patient comprising (i) imaging the breast in a three-dimensional coordinate system, (ii) stereotactically determining the location of the cancerous region in the breast, (iii) optionally determining the volume of the entire cancerous region to be treated, and (iv) while maintaining the breast in a three-dimensional coordinate system that is identical to or corresponds with the three-dimensional coordinate system used in (i), noninvasively exposing the cancerous region of the breast of the patient to a cancer-treatment effective dose of radiation; and equipment for use in such a method. |
FILED | Tuesday, February 26, 2008 |
APPL NO | 12/449827 |
ART UNIT | 3777 — Optical Communications |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/00 (20130101) Original (OR) Class A61B 6/02 (20130101) A61B 6/022 (20130101) A61B 6/0435 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 08785500 | Charney et al. |
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FUNDED BY |
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APPLICANT(S) | Dennis S. Charney (Chappaqua, New York); Sanjay J. Mathew (New York, New York); Husseini K. Manji (Rockville, Maryland); Carlos A. Zarate, Jr. (Germantown, Maryland); John H. Krystal (Woodbridge, Connecticut) |
ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); Yale University (New Haven, Connecticut); National Institute of Health (Rockville, Maryland) |
INVENTOR(S) | Dennis S. Charney (Chappaqua, New York); Sanjay J. Mathew (New York, New York); Husseini K. Manji (Rockville, Maryland); Carlos A. Zarate, Jr. (Germantown, Maryland); John H. Krystal (Woodbridge, Connecticut) |
ABSTRACT | Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years). |
FILED | Tuesday, March 20, 2007 |
APPL NO | 11/688603 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/647 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785602 | Braun et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Jonathan Braun (Tarzana, California); Lynn K. Gordon (Tarzana, California); Kaori Shimazaki Dadgostar (Los Angeles, California); Madhuri Wadehra (Manhattan Beach, California); Kathleen A. Kelly (Pacific Palisades, California); Anna M. Wu (Sherman Oaks, California) |
ABSTRACT | The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The methods and compositions target cancers which express or overexpress EMP2 nucleic acids and polypeptides by targeting EMP2. |
FILED | Monday, October 28, 2013 |
APPL NO | 14/064956 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/387.300 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
US 08785763 | LeMieux et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Melburne C. LeMieux (La Honda, California); Ajay Virkar (Stanford, California); Zhenan Bao (Stanford, California) |
ABSTRACT | Nanostructures are joined using one or more of a variety of materials and approaches. As consistent with various example embodiments, two or more nanostructures are joined at a junction between the nanostructures. The nanostructures may touch or be nearly touching at the junction, and a joining material is deposited and nucleates at the junction to couple the nanostructures together. In various applications, the nucleated joining material facilitates conductivity (thermal and/or electric) between the nanostructures. In some embodiments, the joining material further enhances conductivity of the nanostructures themselves, such as by growing along the nanostructures and/or doping the nanostructures. |
FILED | Friday, August 30, 2013 |
APPL NO | 14/015192 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/244 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08786506 | Ayotte et al. |
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FUNDED BY |
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APPLICANT(S) | Keith Ayotte (Hudson, New Hampshire); Paul Lagasse (Derry, New Hampshire); David Martin (Londonderry, New Hampshire); Anthony Sorrentino (Fitchburg, Massachusetts); Spencer Webb (Windham, New Hampshire); Mark Wheeler (Devens, Massachusetts); George Davison (Nashua, New Hampshire) |
ASSIGNEE(S) | Antennasys, Inc. (Windham, New Hampshire); GBS Positioner, LLC (Nashua, New Hampshire) |
INVENTOR(S) | Keith Ayotte (Hudson, New Hampshire); Paul Lagasse (Derry, New Hampshire); David Martin (Londonderry, New Hampshire); Anthony Sorrentino (Fitchburg, Massachusetts); Spencer Webb (Windham, New Hampshire); Mark Wheeler (Devens, Massachusetts); George Davison (Nashua, New Hampshire) |
ABSTRACT | A low power, lightweight, collapsible and rugged antenna positioner for use in communicating with geostationary, geosynchronous and low earth orbit satellite. By collapsing, invention may be easily carried or shipped in a compact container. May be used in remote locations with simple or automated setup and orientation. Azimuth is adjusted by rotating an antenna in relation to a positioner base and elevation is adjusted by rotating an elevation motor coupled with the antenna. Manual orientation of antenna for linear polarized satellites yields lower weight and power usage. Updates ephemeris or TLE data via satellite. Algorithms used for search including Clarke Belt fallback, transponder/beacon searching switch, azimuth priority searching and tracking including uneven re-peak scheduling yield lower power usage. Orientation aid via user interface allows for smaller azimuth motor, simplifies wiring and lowers weight. Tilt compensation, bump detection and failure contingency provide robustness. |
FILED | Friday, October 21, 2011 |
APPL NO | 13/278927 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Radio wave antennas 343/766 |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 08784856 | Stevens et al. |
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FUNDED BY |
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APPLICANT(S) | Jan F. Stevens (Corvallis, Oregon); Stephen Machado (Pendelton, Oregon); Ralph Reed (Philomath, Oregon); Michael S. Martinez (Salem, Oregon) |
ASSIGNEE(S) | The State of Oregon Acting by and Through the State Boad of Higher Education on Behalf of Oregon State University (Corvallis, Oregon) |
INVENTOR(S) | Jan F. Stevens (Corvallis, Oregon); Stephen Machado (Pendelton, Oregon); Ralph Reed (Philomath, Oregon); Michael S. Martinez (Salem, Oregon) |
ABSTRACT | Particular aspects provide methods for converting glucosinolate in a glucosinolate-containing plant material to glucosinolate breakdown products (GBPs), comprising: providing an amount of processed glucosinolate-containing plant material, the processed material being depleted of oil and glucosinolate converting enzyme activity by virtue of said processing; providing an amount of glucosinolate converting enzyme activity; mixing the processed material with the amount enzyme activity; hydrating the mixture; and incubating the hydrated mixture, wherein the glucosinolates are enzymatically converted to GBPs. Preferably, the processed plant material comprises a oilseed-derived seedmeal material (e.g., meadowfoam seedmeal) from which the oil has been removed by the processing (e.g., solvent extraction and/or heat treatment). In particular embodiments, the glucosinolate converting enzyme activity comprises at least one of a myrosinase activity and a nitrile-forming activity. Additional aspects provide low-fat compositions (e.g., herbicide, fungicide, insecticide, bacteriostatic or bactericidal, cosmetic, cosmeceutical or pharmaceutical) comprising GBPs derived from a glucosinolate-containing plant material. |
FILED | Monday, July 21, 2008 |
APPL NO | 12/664984 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/28 (20130101) A01N 25/32 (20130101) Original (OR) Class A01N 65/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785177 | Yu et al. |
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FUNDED BY |
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APPLICANT(S) | Min-Feng Yu (Norcross, Georgia); Kyungsuk Yum (Berkeley, California); Ning Wang (Champaign, Illinois) |
ASSIGNEE(S) | The Board of Trustees of the University of Illinois, a body Corporate and Politic of the State of Illinois (Urbana, Illinois) |
INVENTOR(S) | Min-Feng Yu (Norcross, Georgia); Kyungsuk Yum (Berkeley, California); Ning Wang (Champaign, Illinois) |
ABSTRACT | Methods for creating a transient nanoscale opening in a cell membrane and methods for transporting a desired species through the nanoscale opening are provided. A nano-sized needle-like tip can be used to mechanically slice the cell membrane to create a transient, localized nanoscale slit. The nanoscale slit may be used for transferring exogenous molecules into a living cell. |
FILED | Monday, November 05, 2012 |
APPL NO | 13/669233 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/285.200 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 08789172 | Stolfo et al. |
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FUNDED BY |
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APPLICANT(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromylis (New York, New York); Elli Androulaki (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromylis (New York, New York); Elli Androulaki (New York, New York) |
ABSTRACT | Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack. In some embodiments, the methods include: selecting a data segment in at least one portion of an electronic document; determining whether the arbitrarily selected data segment can be altered without causing the electronic document to result in an error when processed by a corresponding program; in response to determining that the arbitrarily selected data segment can be altered, arbitrarily altering the data segment in the at least one portion of the electronic document to produce an altered electronic document; and determining whether the corresponding program produces an error state when the altered electronic document is processed by the corresponding program. |
FILED | Wednesday, March 18, 2009 |
APPL NO | 12/406814 |
ART UNIT | 2438 — Cryptography and Security |
CURRENT CPC | Information security 726/22 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
US 08785419 | Murali et al. |
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FUNDED BY |
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APPLICANT(S) | Ramachandran Murali (Swarthmore, Pennsylvania); Mark I. Greene (Penn Valley, Pennsylvania) |
ASSIGNEE(S) | The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Ramachandran Murali (Swarthmore, Pennsylvania); Mark I. Greene (Penn Valley, Pennsylvania) |
ABSTRACT | Method of identifying compounds that modulate intermolecular interactions between a target protein and a modifier are disclosed. Pharmaceutical composition comprising compounds that inhibit intermolecular interactions between a target protein and a modifier are disclosed. Methods of treating individual suffering from inflammatory conditions, undesirable immune responses, immunological conditions and bacterial infections are disclosed. |
FILED | Friday, July 29, 2011 |
APPL NO | 13/194832 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/42 (20130101) A61K 31/17 (20130101) A61K 31/40 (20130101) A61K 31/655 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 08784028 | Clark |
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FUNDED BY |
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APPLICANT(S) | David L. Clark (Manhattan Beach, California) |
ASSIGNEE(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
INVENTOR(S) | David L. Clark (Manhattan Beach, California) |
ABSTRACT | A penetrating fastener has a fastener head and fastener tip spaced apart by a longitudinally oriented fastener shaft. A tetherable washer has a substantially planar base surface having a fastener aperture extending therethrough. A longitudinally oriented wall extends longitudinally upward from at least a portion of the base surface to form a concave fastener cavity configured to receive at least a portion of the fastener head. Two tether apertures extend laterally through the wall and are laterally spaced apart along the wall. Both of the tether apertures are laterally arranged along the wall in a rotationally asymmetric configuration. A first one of the tether apertures is located a second longitudinal distance from the base surface and a second one of the tether apertures is located a third longitudinal distance from the base surface. The tether apertures are configured to simultaneously accept a tether extending through both of the tether apertures. |
FILED | Tuesday, October 16, 2012 |
APPL NO | 13/653142 |
ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Expanded, threaded, driven, headed, tool-deformed, or locked-threaded fastener 411/372 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785134 | Mullen |
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FUNDED BY |
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APPLICANT(S) | Elaine H. Mullen (Alexandria, Virginia) |
ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
INVENTOR(S) | Elaine H. Mullen (Alexandria, Virginia) |
ABSTRACT | Provided are methods of collecting, detecting and altering cells and molecular entities using glycoprotein micelles and vesicles. Glycoprotein vesicles comprising a glycoprotein micelle, at least a monolayer of lectin and/or a monolayer of biologically active glycoproteins are also provided. The invention further provides methods of detecting protein glycosylation using the vesicles of the invention. |
FILED | Monday, November 10, 2008 |
APPL NO | 12/268333 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/82 (20130101) Original (OR) Class G01N 21/94 (20130101) G01N 21/4658 (20130101) G01N 2021/825 (20130101) G01N 2021/7786 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08785483 | Srivastava et al. |
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FUNDED BY |
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APPLICANT(S) | Satish K. Srivastava (Galveston, Texas); Kota V. Ramana (Galveston, Texas); Umesh Yadav (Galveston, Texas) |
ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
INVENTOR(S) | Satish K. Srivastava (Galveston, Texas); Kota V. Ramana (Galveston, Texas); Umesh Yadav (Galveston, Texas) |
ABSTRACT | Embodiments of the invention include methods and compositions involving aldose reductase inhibitors for treating COPD. |
FILED | Friday, December 23, 2011 |
APPL NO | 13/336833 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/360 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08787630 | Rowe |
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FUNDED BY |
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APPLICANT(S) | Robert K. Rowe (Corrales, New Mexico) |
ASSIGNEE(S) | Lumidigm, Inc. (Albuquerque, New Mexico) |
INVENTOR(S) | Robert K. Rowe (Corrales, New Mexico) |
ABSTRACT | A multispectral sensor is provided with an illumination source and a digital imaging system. The illumination source is disposed to provide light at multiple wavelengths to an object. The digital imaging system is disposed to receive light scattered from the object and has a digital array of light detectors and a color filter array. The color filter array has a multiple distributed filter elements, each of which is adapted to transmit light of one of a limited number of specified narrowband wavelength ranges. The color filter array is disposed to filter the light scattered from the object prior to encountering the digital array of light detectors. |
FILED | Wednesday, January 05, 2011 |
APPL NO | 12/985161 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00033 (20130101) Original (OR) Class G06K 9/00899 (20130101) G06K 9/2018 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 22, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140722.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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