FedInvent™ Patents
Patent Details for Tuesday, July 29, 2014
This page was updated on Monday, March 27, 2023 at 04:02 AM GMT
Department of Health and Human Services (HHS)
| US 08790317 | Olbricht et al. |
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| FUNDED BY |
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| APPLICANT(S) | William L. Olbricht (Ithaca, New York); Keith B. Neeves (Philadelphia, Pennsylvania); Conor Foley (Ithaca, New York); Russell T. Mattews (Skaneateles, New York); W. Mark Saltzman (New Haven, Connecticut); Andrew Sawyer (New Haven, Connecticut) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | William L. Olbricht (Ithaca, New York); Keith B. Neeves (Philadelphia, Pennsylvania); Conor Foley (Ithaca, New York); Russell T. Mattews (Skaneateles, New York); W. Mark Saltzman (New Haven, Connecticut); Andrew Sawyer (New Haven, Connecticut) |
| ABSTRACT | An embodiment of the invention is directed to a microfabricated, silicon-based, Convection Enhanced Delivery (CED) device. The device comprises a silicon shank portion, at least one individual parylene channel disposed along at least a part of an entire length of the shank, wherein the channel has one or more dimensioned fluid exit ports disposed at one or more respective locations of the channel and a fluid (drug) input opening. The fluid input opening may be configured or adapted to be connected to a fluid reservoir and/or a pump and/or a meter and/or a valve or other suitable control device(s) or apparatus that supplies and/or delivers fluid (eg, a drug) to the microfabricated device. The device may have multiple channels disposed side by side or in different surfaces of the device. |
| FILED | Tuesday, February 12, 2008 |
| APPL NO | 12/525393 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/264 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790379 | Bottlang et al. |
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| APPLICANT(S) | Michael Bottlang (Portland, Oregon); Steven M. Madey (Portland, Oregon); Kyle Wirtz (Portland, Oregon); Stanley Tsai (Portland, Oregon) |
| ASSIGNEE(S) | Zimmer, Inc. (Warsaw, Indiana) |
| INVENTOR(S) | Michael Bottlang (Portland, Oregon); Steven M. Madey (Portland, Oregon); Kyle Wirtz (Portland, Oregon); Stanley Tsai (Portland, Oregon) |
| ABSTRACT | Embodiments provide methods, apparatuses, and systems for fixation of a fractured bone with a bone plate. In various embodiments, the systems and plates provide elastic suspension of the receiving holes relative to an osteosynthesis plate. This elastic suspension can promote load distribution between the screws that connect a bone segment to the plate, thereby reducing stress risers and load shielding effect. In addition, stress at the screw holes, and within the construct as a whole, is reduced by incorporation of these elastic elements in the plate. Additionally, in some embodiments where fracture healing by callus formation is desired, elastic suspension of the receiving holes relative to the osteosynthesis plate can enable small, controlled amounts of relative motion between bone fragments connected by the plate. This relative motion can promote fracture healing by callus formation. |
| FILED | Wednesday, June 06, 2012 |
| APPL NO | 13/490249 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery 66/289 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790597 | Childs et al. |
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| APPLICANT(S) | Richard W. Childs (Bethesda, Maryland); Herb Cullis (Gaithersburg, Maryland); Sumithira Vasu (Bethesda, Maryland); Phillippe Jean Broussard (Finksburg, Maryland); Kevin Douglas Clark (Gaithersburg, Maryland); Eric Kelsey Harting (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of Americas, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Richard W. Childs (Bethesda, Maryland); Herb Cullis (Gaithersburg, Maryland); Sumithira Vasu (Bethesda, Maryland); Phillippe Jean Broussard (Finksburg, Maryland); Kevin Douglas Clark (Gaithersburg, Maryland); Eric Kelsey Harting (Rockville, Maryland) |
| ABSTRACT | Methods and apparatus for selectively accessing a portion of a sterile cryopreserved sample are disclosed. The apparatus may include a container configured to receive the cryopreserved sample and having a first portion and a second portion, a heat sink chamber surrounding the first portion of the container, and a heat source adjacent to the second portion of the container. The chamber may be configured to maintain a non-accessed portion of the sample in a cryopreserved state. The heat source may be configured to separating an accessed portion of the sample from the non-accessed portion of the sample while maintaining the viability of the accessed portion while the non-accessed portion is maintained in the cryopreserved state. |
| FILED | Tuesday, May 04, 2010 |
| APPL NO | 13/318122 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0252 (20130101) A01N 1/0257 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/0281 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 63/18 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/00 (20130101) B29C 65/04 (20130101) B29C 65/08 (20130101) B29C 65/14 (20130101) B29C 65/18 (20130101) B29C 65/224 (20130101) B29C 65/743 (20130101) B29C 65/1412 (20130101) B29C 65/7443 (20130101) B29C 65/7841 (20130101) B29C 66/024 (20130101) B29C 66/43 (20130101) B29C 66/43 (20130101) B29C 66/0044 (20130101) B29C 66/94 (20130101) B29C 66/0242 (20130101) B29C 66/0242 (20130101) B29C 66/348 (20130101) B29C 66/431 (20130101) B29C 66/818 (20130101) B29C 66/818 (20130101) B29C 66/919 (20130101) B29C 66/949 (20130101) B29C 66/1122 (20130101) B29C 66/1122 (20130101) B29C 66/7373 (20130101) B29C 66/8122 (20130101) B29C 66/8122 (20130101) B29C 66/8122 (20130101) B29C 66/8122 (20130101) B29C 66/8181 (20130101) B29C 66/8242 (20130101) B29C 66/8322 (20130101) B29C 66/9221 (20130101) B29C 66/9231 (20130101) B29C 66/9241 (20130101) B29C 66/9241 (20130101) B29C 66/53262 (20130101) B29C 66/81261 (20130101) B29C 66/81261 (20130101) B29C 66/81811 (20130101) B29C 66/81811 (20130101) B29C 66/81821 (20130101) B29C 66/81831 (20130101) B29C 66/81831 (20130101) B29C 66/81871 (20130101) B29C 66/91213 (20130101) B29C 66/91221 (20130101) B29C 66/91231 (20130101) B29C 66/91421 (20130101) B29C 66/91421 (20130101) B29C 66/91445 (20130101) B29C 66/92445 (20130101) B29C 2035/0822 (20130101) B29C 2793/0054 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2827/12 (20130101) B29K 2827/18 (20130101) B29K 2909/02 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7148 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790635 | Kopecko et al. |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Dennis J. Kopecko (Columbia, Maryland); De-Qi Xu (Silver Spring, Maryland) |
| ABSTRACT | The invention relates to Salmonella typhi Ty21a comprising core-linked Shigella dysenteriae serotype 1 O-specific polysaccharide (O-Ps) and DNA encoding O antigen biosynthesis, said DNA selected from the group consisting of: a) the DNA sequence set out in any one of SEQ ID NOs: 1 and 2 and species homologs thereof; b) DNA encoding Shigella dysenteriae serotype 1 polypeptides encoded by any one of SEQ ID NOs: 1 and 2, and species homologs thereof; and c) DNA encoding a O antigen biosynthesis gene product that hybridizes under moderately stringent conditions to the DNA of (a) or (b); and related sequences, compositions of matter, vaccines, methods of using, and methods of making. |
| FILED | Wednesday, November 28, 2012 |
| APPL NO | 13/687797 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790636 | Centanni et al. |
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| APPLICANT(S) | John M. Centanni (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ASSIGNEE(S) | Stratatech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | John M. Centanni (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides. |
| FILED | Wednesday, January 04, 2012 |
| APPL NO | 13/343314 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790650 | Lee et al. |
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| APPLICANT(S) | Ethan Lee (Brentwood, Tennessee); Pampee P. Young (Brentwood, Tennessee); Josiane Eid (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Ethan Lee (Brentwood, Tennessee); Pampee P. Young (Brentwood, Tennessee); Josiane Eid (Nashville, Tennessee) |
| ABSTRACT | The present invention is directed to monoclonal antibodies and fragments thereof directed to LRP5/6 that find use in the prevention and treatment of cardiac remodeling and cancer. Also disclosed are methods for using such monoclonal antibodies in the prevention and treatment of such diseases. |
| FILED | Monday, April 30, 2012 |
| APPL NO | 13/460242 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/143.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790655 | Carson et al. |
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| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Dennis A. Carson (La Jolla, California); Howard B. Cottam (Escondido, California); Wolfgang Wrasidlo (La Jolla, California); Christina C. N. Wu (Escondido, California); Gregory A. Daniels (San Diego, California) |
| ABSTRACT | The invention provides TLR agonists and conjugates thereof useful in vaccines and to prevent, inhibit or treat a variety of disorders including pathogen infection and asthma. |
| FILED | Tuesday, January 08, 2013 |
| APPL NO | 13/736545 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/194.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790662 | Spellberg et al. |
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| APPLICANT(S) | Brad J. Spellberg (Rancho Palos Verdes, California); Ashraf S. Ibrahim (Irvine, California); John E Edwards, Jr. (Palos Verdes Estates, California) |
| ASSIGNEE(S) | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (Torrance, California) |
| INVENTOR(S) | Brad J. Spellberg (Rancho Palos Verdes, California); Ashraf S. Ibrahim (Irvine, California); John E Edwards, Jr. (Palos Verdes Estates, California) |
| ABSTRACT | The invention is based, in part, on the discovery of a novel cell-based immunotherapy that can recapitulate neutrophil functions in neutropenic individuals afflicted with a microbial infection. The therapeutic methods of the invention are broadly applicable to treat any infection in a neutropenic individual, including infections caused by bacteria, fungi, protozoa, and viruses. The methods of the invention represent a practical, rapid cell-based immunotherapy for refractory infections comprising compositions of activated, irradiated HL-60 cells. |
| FILED | Monday, March 12, 2012 |
| APPL NO | 13/418263 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/274.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790666 | Smith |
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| APPLICANT(S) | Douglas H. Smith (Boothwyn, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Douglas H. Smith (Boothwyn, Pennsylvania) |
| ABSTRACT | The present invention relates to mechanically elongated neurons and provides useful compositions, devices and methods for treating a nerve lesion using such mechanically elongated neurons. |
| FILED | Friday, May 05, 2006 |
| APPL NO | 11/429201 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790678 | Elbert et al. |
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| APPLICANT(S) | Donald Elbert (Clayton, Missouri); Megan Kaneda (St. Louis, Missouri); Evan Scott (University City, Missouri); Brad Wacker (St. Louis, Missouri); Shannon Alford (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Donald Elbert (Clayton, Missouri); Megan Kaneda (St. Louis, Missouri); Evan Scott (University City, Missouri); Brad Wacker (St. Louis, Missouri); Shannon Alford (Cambridge, Massachusetts) |
| ABSTRACT | The invention generally relates to substrates and surfaces having substrates. Generally speaking, the substrates may be thinly layered substrates, and the surfaces may comprise thinly layered substrates. Additionally, the substrates may comprise a multifunctional water soluble polymer and a lipoprotein and the surfaces may comprise a multifunctional water soluble polymer and a lipoprotein. |
| FILED | Friday, March 02, 2007 |
| APPL NO | 12/281399 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/423 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790680 | Chancellor et al. |
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| APPLICANT(S) | Michael B. Chancellor (Pittsburgh, Pennsylvania); Johnny Huard (Wexford, Pennsylvania); Christopher Capelli (Kenosha, Wisconsin); Steve Chung (Pittsburgh, Pennsylvania); Michael S. Sacks (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburg Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Michael B. Chancellor (Pittsburgh, Pennsylvania); Johnny Huard (Wexford, Pennsylvania); Christopher Capelli (Kenosha, Wisconsin); Steve Chung (Pittsburgh, Pennsylvania); Michael S. Sacks (Pittsburgh, Pennsylvania) |
| ABSTRACT | A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition. |
| FILED | Friday, March 11, 2011 |
| APPL NO | 13/046120 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3629 (20130101) A61L 27/3679 (20130101) Original (OR) Class A61L 27/3834 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) C12N 5/0668 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790863 | Branton et al. |
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| APPLICANT(S) | Daniel Branton (Lexington, Massachusetts); Anpan Han (Braband, Denmark); Jene A. Golovchenko (Lexington, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel Branton (Lexington, Massachusetts); Anpan Han (Braband, Denmark); Jene A. Golovchenko (Lexington, Massachusetts) |
| ABSTRACT | In a method for imaging a solid state substrate, a vapor is condensed to an amorphous solid water condensate layer on a surface of a solid state substrate. Then an image of at least a portion of the substrate surface is produced by scanning an electron beam along the substrate surface through the water condensate layer. The water condensate layer integrity is maintained during electron beam scanning to prevent electron-beam contamination from reaching the substrate during electron beam scanning. Then one or more regions of the layer can be locally removed by directing an electron beam at the regions. A material layer can be deposited on top of the water condensate layer and any substrate surface exposed at the one or more regions, and the water condensate layer and regions of the material layer on top of the layer can be removed, leaving a patterned material layer on the substrate. |
| FILED | Wednesday, October 26, 2011 |
| APPL NO | 13/881504 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/296 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790869 | Blonder et al. |
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| APPLICANT(S) | Josip Blonder (Frederick, Maryland); Bih-Rong Wei (Rockville, Maryland); Donald J. Johann (Bethesda, Maryland); Timothy D. Veenstra (Jefferson, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Josip Blonder (Frederick, Maryland); Bih-Rong Wei (Rockville, Maryland); Donald J. Johann (Bethesda, Maryland); Timothy D. Veenstra (Jefferson, Maryland) |
| ABSTRACT | Disclosed herein is a method of identifying a tumor biomarker. In one example, a tumor biomarker is identified by obtaining a peripheral biological fluid sample from a subject with a tumor as well as a tumor sample and an adjacent non-tumor sample from such subject. A protein expression profile is detected in the peripheral biological fluid sample, tumor sample and adjacent non-tumor sample. The protein expression profiles of the peripheral biological fluid sample, tumor sample and adjacent non-tumor sample are then compared, wherein an increase in expression of a specific protein in the tumor sample and peripheral biological fluid sample but not in the adjacent non-tumor sample indicates that the specific protein is a biomarker of the tumor. Also disclosed herein is a gene profiling signature that can be used to diagnosis a subject with renal cell carcinoma (RCC) or to identify agents with therapeutic potential to treat RCC. Thus, methods of diagnosing a subject with RCC are disclosed. Methods are also provided for identifying agents that alter an activity of a RCC biomarker. |
| FILED | Friday, March 20, 2009 |
| APPL NO | 13/257580 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/68 (20130101) G01N 33/574 (20130101) Original (OR) Class G01N 33/6842 (20130101) G01N 33/6848 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790891 | Irimia |
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| APPLICANT(S) | Daniel Irimia (Charlestown, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Daniel Irimia (Charlestown, Massachusetts) |
| ABSTRACT | Certain isolated motile cells spontaneously migrate unidirectionally through a mechanically confined space, such as a microcapillary channel, in the absence of an external gradient (e.g., a chemical gradient). Assays and methods for detecting motile cells, and identifying chemical agents that inhibit cell migration, can include detecting the movement of motile cancer cells through a microcapillary channel. |
| FILED | Friday, March 19, 2010 |
| APPL NO | 13/257464 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790922 | Tuschl et al. |
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| APPLICANT(S) | Thomas Tuschl (Brooklyn, New York); Phillip D. Zamore (Northborough, Massachusetts); Phillip A. Sharp (Newton, Massachusetts); David P. Bartel (Brookline, Massachusetts) |
| ASSIGNEE(S) | Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V. (Munich, Germany); Massachusetts Institute of Technology (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Thomas Tuschl (Brooklyn, New York); Phillip D. Zamore (Northborough, Massachusetts); Phillip A. Sharp (Newton, Massachusetts); David P. Bartel (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications. |
| FILED | Monday, October 04, 2010 |
| APPL NO | 12/897759 |
| ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790924 | Sullenger et al. |
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| APPLICANT(S) | Bruce A. Sullenger (Durham, North Carolina); Shahid Nimjee (Durham, North Carolina); Sabah Oney (Palo Alto, California); Nanette Que-Gewirth (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Shahid Nimjee (Durham, North Carolina); Sabah Oney (Palo Alto, California); Nanette Que-Gewirth (Durham, North Carolina) |
| ABSTRACT | The present invention relates, in general, to receptors and to platelet aggregation and, in particular, to a method of inhibiting platelet aggregation using an aptamer that binds to and inhibits the activity of a receptor, such as glycoprotein IIb/IIIa (gpIIb/IIIa), and to aptamers suitable for use in such a method. The invention also relates to antidotes to antiplatelet agents and to methods of using such antidotes to reverse aptamer-induced platelet inhibition. The invention further relates to von Willebrand Factor (VWF) inhibitors, and antidotes therefore, and to methods of using same. |
| FILED | Monday, November 14, 2011 |
| APPL NO | 13/296045 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790925 | Lu et al. |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Kurt Q. Lu (Cleveland Heights, Ohio); Kevin D. Cooper (Moreland Hills, Ohio) |
| ABSTRACT | A method of generating a hyper iNOS expressing cell includes administering to a myeloid derived cell an amount of a PPARγ agonist and an IL-6/STAT3 signaling pathway antagonist effective to substantially inhibit STAT3 activation in the cell and administering an inflammatory insult to the cell to stimulate hyper iNOS expression from the cell. |
| FILED | Thursday, February 28, 2013 |
| APPL NO | 13/780503 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/375 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790931 | Beebe et al. |
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| FUNDED BY |
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| APPLICANT(S) | David J. Beebe (Monona, Wisconsin); Jay Warrick (Madison, Wisconsin); Erwin Berthier (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David J. Beebe (Monona, Wisconsin); Jay Warrick (Madison, Wisconsin); Erwin Berthier (Madison, Wisconsin) |
| ABSTRACT | A method is provided for collecting a concentration of particles from a sample fluid containing the particles. The method includes the steps of providing a microfluidic device. The microfluidic device includes an input channel, an output channel and a collection region. The input channel has an input end and an output end. The output channel has an input end and an output end. The collection region interconnects the output end of the input channel and the input end of the output channel. The sample fluid flows through the input channel and the output channel at a first velocity and through the collection region at a second velocity less than the first velocity such that the particles collect in therein. |
| FILED | Friday, April 02, 2010 |
| APPL NO | 12/753290 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2300/0803 (20130101) B01L 2300/0809 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) Original (OR) Class G01N 2001/383 (20130101) G01N 2001/4083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791062 | Hsu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Tracy Hsu (Newhall, California); Samir M. Mitragotri (Santa Barbara, California) |
| ABSTRACT | The present disclosure provides peptides and peptide compositions, which facilitate the delivery of an active agent or an active agent carrier wherein the compositions are capable of penetrating the stratum corneum (SC) and/or the cellular membranes of viable cells. |
| FILED | Friday, July 26, 2013 |
| APPL NO | 13/952525 |
| ART UNIT | 1675 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48246 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791068 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Terence E. Martin (Chicago, Illinois); F. Gary Toback (Chicago, Illinois); Margaret Walsh-Reitz (River Forest, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Terence E. Martin (Chicago, Illinois); F. Gary Toback (Chicago, Illinois); Margaret Walsh-Reitz (River Forest, Illinois) |
| ABSTRACT | A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease and gastric ulcers. |
| FILED | Thursday, August 30, 2012 |
| APPL NO | 13/599417 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/7.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791073 | West et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jennifer L. West (Pearland, Texas); Ho-Wook Jun (Houston, Texas); Lakeshia J. Taite (Grove Hill, Alabama) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jennifer L. West (Pearland, Texas); Ho-Wook Jun (Houston, Texas); Lakeshia J. Taite (Grove Hill, Alabama) |
| ABSTRACT | Peptide-modified polyurethanes comprising the reaction product of an isocyanate, a chain extender, and a peptide are provided. Also provided processes for making a peptide-modified polyurethane comprising: providing an isocyanate; providing a chain extender; providing a peptide; and allowing the isocyanate, chain extender, and peptide to react thereby forming the peptide-modified polyurethane, as well as methods for treating a subject comprising: providing a peptide-modified polyurethane that comprises the reaction product of an isocyanate, a chain extender, and a peptide; and administering the peptide-modified polyurethane to the subject. |
| FILED | Monday, May 16, 2005 |
| APPL NO | 11/129941 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Original (OR) Class A61K 38/17 (20130101) A61K 47/48192 (20130101) A61K 47/48215 (20130101) A61K 47/48715 (20130101) Peptides C07K 7/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/08 (20130101) C08G 18/6446 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791074 | Leppla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stephen Leppla (Bethesda, Maryland); Shi-Hui Liu (Gaithersburg, Maryland); Sarah Netzel-Arnett (Gaithersburg, Maryland); Henning Birkedal-Hansen (Bethesda, Maryland); Thomas Bugge (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Stephen Leppla (Bethesda, Maryland); Shi-Hui Liu (Gaithersburg, Maryland); Sarah Netzel-Arnett (Gaithersburg, Maryland); Henning Birkedal-Hansen (Bethesda, Maryland); Thomas Bugge (Bethesda, Maryland) |
| ABSTRACT | The present invention provides methods of specifically targeting compounds to cells overexpressing matrix metalloproteinases, plasminogen activators, or plasminogen activator receptors, by administering a compound and a mutant protective antigen protein comprising a matrix metalloproteinase or a plasminogen activator-recognized cleavage site in place of the native protective antigen furin-recognized cleavage site, wherein the mutant protective antigen is cleaved by a matrix metalloproteinase or a plasminogen activator overexpressed by the cell, thereby translocating into the cell a compound comprising a lethal factor polypeptide comprising a protective antigen binding site. |
| FILED | Monday, October 20, 2008 |
| APPL NO | 12/288482 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791075 | Melnick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ari Melnick (New York, New York); Leandro Cerchietti (New York, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Ari Melnick (New York, New York); Leandro Cerchietti (New York, New York) |
| ABSTRACT | The invention is directed to a compound that binds to a BCL6 lateral groove and prevents binding of a corepressor to the lateral groove. The present invention is further directed to methods for blocking corepressor binding to a BCL6 lateral groove, methods for inhibiting BCL6 repression in a mammalian cell, and methods for treating a mammal with cancer, wherein the cancer requires BCL6 repression. The present invention is further directed to polypeptides comprising a portion of the corepressor binding site for BCL6 and related polynucleotides and vectors. |
| FILED | Wednesday, June 10, 2009 |
| APPL NO | 12/737122 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/04 (20130101) A61K 38/08 (20130101) A61K 47/48315 (20130101) Peptides C07K 7/00 (20130101) C07K 7/06 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791079 | O'Rourke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brian O'Rourke (Sparks, Maryland); Ting Liu (Parkville, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Brian O'Rourke (Sparks, Maryland); Ting Liu (Parkville, Maryland) |
| ABSTRACT | Methods and compounds for preventing or reducing the toxic side effects of cardiac glycosides by inhibiting the mitochondrial sodium-calcium exchanger (mNCE) are provided. Methods and compositions for preventing or reducing the occurrence of conditions associated with heart failure, including, but not limited to, sudden cardiac death and contractile decompensation, by inhibiting the mNCE also are provided. |
| FILED | Thursday, March 11, 2010 |
| APPL NO | 13/255593 |
| ART UNIT | 1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/554 (20130101) A61K 31/7048 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791081 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lili Liu (Macedonia, Ohio); Stanton Gerson (Hunting Valley, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Lili Liu (Macedonia, Ohio); Stanton Gerson (Hunting Valley, Ohio) |
| ABSTRACT | A method of treating a neoplastic disease in a subject includes administering to neoplastic cells of the subject an MGMT inhibitor and at least one of an antimitotic agent or a DNA damaging agent. |
| FILED | Friday, February 29, 2008 |
| APPL NO | 12/529643 |
| ART UNIT | 1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/43 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791082 | Rossi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John J. Rossi (Alta Loma, California); Dongho Kim (Los Angeles, California); Patric Lundberg (Rancho Cucamonga, California); Edouard Cantin (Alhambra, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | John J. Rossi (Alta Loma, California); Dongho Kim (Los Angeles, California); Patric Lundberg (Rancho Cucamonga, California); Edouard Cantin (Alhambra, California) |
| ABSTRACT | Double-stranded and single-stranded RNA molecules, and their use in methods for inducing interferon are provided. The interferon induction provides anti-viral and other medically useful effects, such as anti-cancer effects. Also provided are methods for reducing or inhibiting interferon induction exhibited by such molecules, particularly siRNA and shRNA molecules produced in vitro. |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/859306 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791104 | Glick |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Gary D. Glick (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides novel 1,4-benzodiazepine-2,5-dione compounds, and methods of using novel 1,4-benzodiazepine-2,5-dione compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like. |
| FILED | Friday, May 17, 2013 |
| APPL NO | 13/896879 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/221 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791110 | Amberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sean M. Amberg (Corvallis, Oregon); Dongcheng Dai (Corvallis, Oregon); Tove C. Bolken (Keizer, Oregon); Dennis E. Hruby (Albany, Oregon) |
| ASSIGNEE(S) | Siga Technologies, Inc. (Corvallis, Oregon) |
| INVENTOR(S) | Sean M. Amberg (Corvallis, Oregon); Dongcheng Dai (Corvallis, Oregon); Tove C. Bolken (Keizer, Oregon); Dennis E. Hruby (Albany, Oregon) |
| ABSTRACT | Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses. |
| FILED | Thursday, December 29, 2011 |
| APPL NO | 13/339478 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/231.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791116 | Watterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Daniel Martin Watterson (Douglas, Michigan); Linda J. Van Eldik (Lexington, Kentucky); Heather Behanna (Chicago, Illinois); Hantamalala Ralay Ranaivo (Chicago, Illinois) |
| ABSTRACT | Pyridazinyl compounds, compositions and related methods of use. |
| FILED | Monday, October 01, 2012 |
| APPL NO | 13/632920 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/247 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791135 | Ghosh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arun K. Ghosh (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Arun K. Ghosh (West Lafayette, Indiana) |
| ABSTRACT | Novel compounds and compositions for treating patients in need of relief from HIV, AIDS, and AIDS-related diseases are described. Methods for treating HIV, AIDS, and AIDS-related diseases using the compounds described herein are also described. |
| FILED | Wednesday, July 01, 2009 |
| APPL NO | 13/001339 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/315 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791149 | McKnight et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Steven L. McKnight (Dallas, Texas); Andrew A. Pieper (Iowa City, Iowa); Joseph M. Ready (Carrollton, Texas); Jef K. De Brabander (Flower Mound, Texas) |
| ABSTRACT | This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protecting from neuron cell death. |
| FILED | Monday, January 14, 2013 |
| APPL NO | 13/740807 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/403 (20130101) A61K 31/404 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/4045 (20130101) A61K 31/4439 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/14 (20130101) C07D 209/88 (20130101) C07D 401/06 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 413/06 (20130101) C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791233 | Zhang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ming Zhang (Glencoe, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Ming Zhang (Glencoe, Illinois) |
| ABSTRACT | The present invention provides maspin-related compositions and methods of use thereof. In particular, the present invention provides maspin-related compositions, and methods or use thereof, for the promotion of cell adhesion. |
| FILED | Wednesday, May 23, 2012 |
| APPL NO | 13/478904 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791234 | Sinko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Patrick J. Sinko (Annandale, New Jersey); Xiaoping Zhang (Piscataway, New Jersey); Zoltan Szekely (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Patrick J. Sinko (Annandale, New Jersey); Xiaoping Zhang (Piscataway, New Jersey); Zoltan Szekely (New Brunswick, New Jersey) |
| ABSTRACT | Peptide ligands for transporting therapeutic agents across the intestinal epithelial barrier that ordinarily are inadequately absorbed and must be delivered by alternative means, which contain an isolated amino acid sequence wherein at least one pair of amino acids are of an opposite charge and the pair members are separated by a spacer of 1-12 amino acid residues including at least one hydrophobic amino acid, and wherein the length of the amino acid sequence is greater than 5 and less than 20 amino acids. Pharmaceutical compositions for gastro-intestinal delivery and methods for the gastrointestinal delivery of poorly absorbed therapeutic agents are also disclosed. |
| FILED | Friday, October 14, 2011 |
| APPL NO | 13/879205 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791258 | Chang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher J. Chang (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher J. Chang (Berkeley, California) |
| ABSTRACT | The present invention provides a novel class of pro-fluorescent probes for reactive oxygen species (ROS). One exemplary probe is mitochondria peroxy yellow 1 (MitoPY1), a new type of flurophore for imaging mitochondrial H2O2 in living cells with ROS and spatial specificity. The invention also provides methods of using pro-fluorescent probes to detect analytes. One exemplary method comprises using a pro-fluorescent probe of the invention to detect an explosive. |
| FILED | Monday, June 08, 2009 |
| APPL NO | 12/997234 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/229 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791262 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Li Deng (Newton Lower Falls, Massachusetts); Hongming Li (Scotch Plains, New Jersey) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Li Deng (Newton Lower Falls, Massachusetts); Hongming Li (Scotch Plains, New Jersey) |
| ABSTRACT | In certain embodiments, the present invention relates to methods for asymmetric Friedel-Crafts alkylation catalyzed by bifunctional cinchona alkaloids. In certain embodiments, the catalyst is a 6′-OH cinchona alkaloid. In certain embodiments, the electrophile is an α-ketoester or aldehyde. In certain embodiments, the nucleophile is an aromatic heterocycle. In certain embodiments, the nucleophile is an aromatic N-containing heterocycle. In certain embodiments, the nucleophile is an indole. In certain embodiments, the methods of the invention are relatively insensitive to concentration, temperature, air and moisture. |
| FILED | Friday, December 01, 2006 |
| APPL NO | 12/095843 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791285 | Santra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Swadeshmukul Santra (Orlando, Florida); James Turkson (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Swadeshmukul Santra (Orlando, Florida); James Turkson (Orlando, Florida) |
| ABSTRACT | An activatable nanoprobe is provided having a core component and an active agent associated with the core component via a bond configured to be cleaved upon exposure to an endogenous compound. |
| FILED | Monday, June 11, 2012 |
| APPL NO | 13/493815 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | Organic compounds 556/31 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791696 | Grafendorfer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Grafendorfer (Meno Park, California); Paul David Calderon (Castro Valley, California); Fraser Robb (Aurora, Ohio); James S. Tropp (Berkeley, California); Greig Cameron Scott (Palo Alto, California); Shreyas Vasanawala (Stanford, California) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Thomas Grafendorfer (Meno Park, California); Paul David Calderon (Castro Valley, California); Fraser Robb (Aurora, Ohio); James S. Tropp (Berkeley, California); Greig Cameron Scott (Palo Alto, California); Shreyas Vasanawala (Stanford, California) |
| ABSTRACT | A system and method for generating preamplifier feedback in magnetic resonance imaging (MRI) systems are provided. A preamplifier arrangement for the MRI system includes a plurality of preamplifiers with each of the preamplifiers connected to a different channel of a multi-channel coil array of the MRI system. The preamplifier arrangement further includes a feedback network connected to each of the plurality of preamplifiers with each of the feedback networks configured to generate negative feedback at one or more oscillation frequencies. |
| FILED | Friday, April 09, 2010 |
| APPL NO | 12/757782 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791699 | Hernandez-Garcia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Luis Hernandez-Garcia (Ann Arbor, Michigan); Jennifer Vannest (Cincinnati, Ohio); Scott Holland (Cincinnati, Ohio); Vincent Schmithorst (Batavia, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Luis Hernandez-Garcia (Ann Arbor, Michigan); Jennifer Vannest (Cincinnati, Ohio); Scott Holland (Cincinnati, Ohio); Vincent Schmithorst (Batavia, Ohio) |
| ABSTRACT | This disclosure is generally drawn to methods, systems, appliances and/or apparati related to obtaining magnetic resonance imaging (MRI) images. More specifically, the disclosure relates to obtaining MRI images using arterial spin labeling (ASL) and blood-oxygen-level dependence functional magnetic resonance imaging (BOLD-fMRI) techniques. In some examples, a method of obtaining magnetic resonance imaging (MRI) image(s) is provided. An example method may include providing arterial spin labeling (ASL) labeling, obtaining at least one ASL acquisition after ASL labeling, and obtaining at least one blood-oxygen-level dependence functional magnetic resonance imaging (BOLD-fMRI) acquisition after ASL labeling. |
| FILED | Tuesday, May 31, 2011 |
| APPL NO | 13/118943 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/56366 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792156 | Kieu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Khanh Kieu (Tuscon, Arizona); Nasser Peyghambarian (Tuscon, Arizona); Xiaoliang Sunney Xie (Lexington, Massachusetts); Christian W. Freudiger (Cambridge, Massachusetts); Dan Fu (Somerville, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Khanh Kieu (Tuscon, Arizona); Nasser Peyghambarian (Tuscon, Arizona); Xiaoliang Sunney Xie (Lexington, Massachusetts); Christian W. Freudiger (Cambridge, Massachusetts); Dan Fu (Somerville, Massachusetts) |
| ABSTRACT | An illumination system is disclosed for providing dual-excitation wavelength illumination for non-linear optical microscopy and micro-spectroscopy. The illumination system includes a laser system, an optical splitting means, a frequency shifting system, and a picosecond amplifier system. The laser system includes a laser for providing a first train of pulses at a center optical frequency ω1. The optical splitting means divides the first train of pulses at the center optical frequency ω1 into two trains of pulses. The frequency shifting system shifts the optical frequency of one of the two trains of pulses to provide a frequency shifted train of pulses. The picosecond amplifier system amplifies the frequency shifted train of pulses to provide an amplified frequency-shifted train of pulses having a pulse duration of at least 0.5 picoseconds. |
| FILED | Tuesday, January 17, 2012 |
| APPL NO | 13/351831 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/327 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792976 | Gilja et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vikash Gilja (San Francisco, California); Paul Nuyujukian (Stanford, California); Cynthia A Chestek (Menlo Park, California); John P Cunningham (Saratoga, California); Byron M. Yu (San Jose, California); Stephen I Ryu (Menlo Park, California); Krishna V. Shenoy (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Vikash Gilja (San Francisco, California); Paul Nuyujukian (Stanford, California); Cynthia A Chestek (Menlo Park, California); John P Cunningham (Saratoga, California); Byron M. Yu (San Jose, California); Stephen I Ryu (Menlo Park, California); Krishna V. Shenoy (Palo Alto, California) |
| ABSTRACT | Artificial control of a prosthetic device is provided. A brain machine interface contains a mapping of neural signals and corresponding intention estimating kinematics (e.g. positions and velocities) of a limb trajectory. The prosthetic device is controlled by the brain machine interface. During the control of the prosthetic device, a modified brain machine interface is developed by modifying the vectors of the velocities defined in the brain machine interface. The modified brain machine interface includes a new mapping of the neural signals and the intention estimating kinematics that can now be used to control the prosthetic device using recorded neural brain signals from a user of the prosthetic device. In one example, the intention estimating kinematics of the original and modified brain machine interface includes a Kalman filter modeling velocities as intentions and positions as feedback. |
| FILED | Thursday, February 17, 2011 |
| APPL NO | 12/932070 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0476 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Original (OR) Class A61F 4/00 (20130101) A61F 2002/704 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793074 | Aurora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rajeev Aurora (Wildwood, Missouri); Maureen J. Donlin (Kirkwood, Missouri); John E. Tavis (Kirkwood, Missouri) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
| INVENTOR(S) | Rajeev Aurora (Wildwood, Missouri); Maureen J. Donlin (Kirkwood, Missouri); John E. Tavis (Kirkwood, Missouri) |
| ABSTRACT | Methods of identifying targets for designing a therapeutic agent are disclosed. These methods comprise: determining an amino acid sequence of one or more polypeptides of each isolate of a plurality of isolates of a biological system; identifying covariance pairs of amino acid residues; establishing a network comprising the covariance pairs; and identifying one or more hub residue positions, wherein a hub residue position comprises a target for designing a therapeutic agent if the hub residue position has a rank order in the 40th percentile or greater. In other aspects, methods are disclosed for selecting a therapy for an infectious disorder. In various configurations, these methods comprise: determining amino acids occupying a plurality of diagnostic amino acid residue positions comprised by one or more polypeptides encoded by an infectious agent infecting a subject; and assigning the infectious agent infecting the subject to one covariance network selected from a plurality of covariance networks, wherein each network comprises a unique rank order of hubs with respect to the other networks, and whereby the therapy is selected on the basis of the covariance network assignment. |
| FILED | Monday, June 23, 2008 |
| APPL NO | 12/144030 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7056 (20130101) A61K 31/7056 (20130101) A61K 38/212 (20130101) A61K 38/212 (20130101) Electric Digital Data Processing G06F 19/22 (20130101) Original (OR) Class G06F 19/24 (20130101) G06F 19/3443 (20130101) G06F 19/3456 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE45053 | Whitehead et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Department of Health, Washington D.C. (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Stephen S. Whitehead (Bethesda, Maryland); Brian R. Murphy (Bethesda, Maryland); Kathryn A. Hanley (Las Cruces, New Mexico); Joseph E. Blaney (Gettysburg, Pennsylvania); Ching-Juh Lai (Bethesda, Maryland) |
| ABSTRACT | A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines. |
| FILED | Friday, May 17, 2013 |
| APPL NO | 13/896411 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/218.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08789261 | Clifton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher Clifton (Bloomfield, Indiana); Dean L. Jones (Bloomington, Indiana); Philip S. Mitchell (Springville, Indiana); David Myers (Bloomfield, Indiana); James M. Pruett (Montgomery, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Clifton (Bloomfield, Indiana); Dean L. Jones (Bloomington, Indiana); Philip S. Mitchell (Springville, Indiana); David Myers (Bloomfield, Indiana); James M. Pruett (Montgomery, Indiana) |
| ABSTRACT | A vehicle is provided that includes a shelter thereon that includes electronics therein. The shelter includes ports on the exterior thereof that permit data and power exchange between the vehicle and another similarly configured vehicle. The vehicle further includes dedicated wiring raceways that separate wiring having different uses. |
| FILED | Friday, January 29, 2010 |
| APPL NO | 12/696861 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal working 029/601 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08789423 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James P. Rogers (Redondo Beach, California); Abbas Mandvi (Brea, California); Chi Chin Lee (Riverside, California); Chhour M. Thong (Buena Park, California); Anthony Charles Buono (Santa Ana, California) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | James P. Rogers (Redondo Beach, California); Abbas Mandvi (Brea, California); Chi Chin Lee (Riverside, California); Chhour M. Thong (Buena Park, California); Anthony Charles Buono (Santa Ana, California) |
| ABSTRACT | A method and apparatus for testing an object. A testing unit comprises a base structure, a contact structure, and piezoelectric transducers. The piezoelectric transducers are located between the base structure and the contact structure. A preload is present on the piezoelectric transducers. |
| FILED | Wednesday, November 02, 2011 |
| APPL NO | 13/287784 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/663 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08789426 | Pekarek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven D. Pekarek (West Lafayette, Indiana); Kevin A. Rosenbaum (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Steven D. Pekarek (West Lafayette, Indiana); Kevin A. Rosenbaum (West Lafayette, Indiana) |
| ABSTRACT | A system and method employing a piezoelectric sensor for quasi-static force measurement substantially free of drift and with improved low-frequency response. The output signal from the sensor is sampled and integrated using digital techniques that include a drift compensation algorithm. The algorithm continually monitors the sensor output and estimates bias errors that will cause the output to drift. |
| FILED | Monday, August 15, 2011 |
| APPL NO | 13/210106 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/777 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08789453 | Morrison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew MacDonald Morrison (Leonardtown, Maryland); Robert Harry Schilder (Great Mills, Maryland) |
| ABSTRACT | A dispenser pod, which includes a dispenser chassis with a first chassis end, a second chassis end and a chassis chamber, a first chassis end cover for covering the first chassis end, a second chassis end cover for covering the second chassis end, a launch system, and at least one sway brace. The first chassis end cover has at least one expendable passageway for accepting an expendable launch canister such that the expendable launch canister can enter the chassis chamber. The launch system is for expelling the expendable launch canister from the chassis chamber and through the expendable passageway. The at least one sway brace is for securing the expendable launch canister within the chassis chamber. |
| FILED | Thursday, February 21, 2013 |
| APPL NO | 13/772717 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08789454 | Roland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles M. Roland (Waldorf, Maryland); Daniel M. Fragiadakis (Alexandria, Virginia); Raymond M. Gamache (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Charles M. Roland (Waldorf, Maryland); Daniel M. Fragiadakis (Alexandria, Virginia); Raymond M. Gamache (Indian Head, Maryland) |
| ABSTRACT | An armor system with a composite laminate having at least four alternating layers (two bi-layers) of a first material and a second material, the first material having a lower acoustic impedance than the second material. The first material is a viscoelastic polymer with a glass transition temperature less than the expected operational temperature range, and the second material can be a hard material such as steel, aluminum, or ceramic. The laminate can include many alternating layers of elastomer and hard material, and can be adhered or affixed to a thicker armor substrate. Additional protective elements such as corrugated metal-ceramic panels and armored glass cylinders can be added to improve resistance to armor piercing rounds, explosively formed penetrators, or other threats. |
| FILED | Wednesday, July 17, 2013 |
| APPL NO | 13/944073 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0421 (20130101) Original (OR) Class F41H 5/0428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08789469 | Evangelisti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthew Evangelisti (Denville, New Jersey); Steve Kotefski (Bloomingdale, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Evangelisti (Denville, New Jersey); Steve Kotefski (Bloomingdale, New Jersey) |
| ABSTRACT | A grenade fuze assembly includes a fuze body, a striker lever pivotally mounted to the fuze body, and a pull pin assembly. The pull pin assembly includes a pull pin attached to a pull ring and a pull pin retainer fixed to the pull pin on a side of the striker lever opposite the pull ring. The pull pin retainer includes a through hole. The two legs of the pull pin are disposed in the through hole and deformed around the retainer to fix the retainer to the pull pin. The retainer includes a pair of nest areas on opposing sides of the retainer. The free end of each of the two pull pin legs is disposed in a respective nest area. |
| FILED | Thursday, September 26, 2013 |
| APPL NO | 14/037731 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/486 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790059 | Kerechanin, II |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles W. Kerechanin, II (Columbia, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Charles W. Kerechanin, II (Columbia, Maryland) |
| ABSTRACT | A washer assembly includes a threaded fastener head engaging portion and a surface engaging portion. The threaded fastener head engaging portion includes a head engaging face configured to lie in a plane substantially perpendicular to a longitudinal length of a threaded fastener passed through an opening at an axial center of the threaded fastener head engaging portion. The surface engaging portion includes a slot and a surface engaging face. The slot extends through the surface engaging portion along a line extending through an axial center of the surface engaging portion. An adjustable interface is defined between the surface engaging portion and the threaded fastener head engaging portion to enable the slot to receive the threaded fastener such that the surface engaging face lies parallel to a surface that is not perpendicular to the longitudinal length of the threaded fastener. |
| FILED | Tuesday, March 27, 2012 |
| APPL NO | 13/430878 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 43/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790282 | Jung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ranu Jung (Scottsdale, Arizona); Shah Vikram Jung (Freemont, California); Brundavani Srimattirumalaparle (Glendale, Arizona) |
| ASSIGNEE(S) | Advensys, LLC (Scottsdale, Arizona) |
| INVENTOR(S) | Ranu Jung (Scottsdale, Arizona); Shah Vikram Jung (Freemont, California); Brundavani Srimattirumalaparle (Glendale, Arizona) |
| ABSTRACT | A neuromorphic controlled powered orthotic and prosthetic system and device including a custom or universal fit fixed-ankle orthosis, to stabilize or immobilize an injured lower limb or act as an ankle prosthesis, and an actuated or powered articulated false-foot connected to the fixed-ankle orthosis or the prosthesis to form an actuated articulated false-foot orthosis. Associated with or mounted on the actuated articulated false-foot, or in or on the body, are sensors for sensing the intent of the subject to move, and the movement range of the articulating false-foot or AAFO and an environmental perturbation. An actuator is used to drive the articulated false-foot orthosis. The system and device further include a controller having an electronic circuit with a biomimetic design based on knowledge of connectivity of neurons within the spinal cord of a primitive vertebrate. The system and device include an electronic circuit made from analog very large scale integrated components and discrete electronic components capable of autonomously generating cyclic voltage output. An integral power supply serves the portable controller and AAFO. |
| FILED | Monday, November 10, 2008 |
| APPL NO | 12/268430 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Surgery: Kinesitherapy 61/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790612 | Long et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey W Long (Alexandria, Virginia); Debra R Rolison (Arlington, Virginia); Benjamin P. Hahn (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey W Long (Alexandria, Virginia); Debra R Rolison (Arlington, Virginia); Benjamin P. Hahn (Bethesda, Maryland) |
| ABSTRACT | A composition comprising: a metal oxide of a first metal ions and second metal ions; an electrically conductive material; and a binder material. The second metal ions have a higher oxidation state than the first metal ions. The presence of the second metal ion increases the number of metal cation vacancies. A method of: dissolving salts of a first metal ion and a second metal ion in water to form a solution; heating the solution to a temperature of about 80-90° C.; and adding a base to the solution to precipitate nanoparticles of a metal oxide of the first metal ion and the second metal ion. |
| FILED | Wednesday, February 06, 2013 |
| APPL NO | 13/760151 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of inorganic compounds 423/594.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790634 | Benny-Ratsaby et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ofra Benny-Ratsaby (Boston, Massachusetts); Robert D'Amato (Lexington, Massachusetts); Takeru Yoshimura (Brookline, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ofra Benny-Ratsaby (Boston, Massachusetts); Robert D'Amato (Lexington, Massachusetts); Takeru Yoshimura (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by administering compositions and formulations comprising MetAP-2 inhibitors as disclosed herein. The composition comprises a formulation of a fumagillol derivative that retains anti-inflammation activity and is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety. |
| FILED | Monday, December 28, 2009 |
| APPL NO | 12/648155 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/78.380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790776 | Zeller |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frank Zeller (Austin, Texas) |
| ASSIGNEE(S) | Texas Research International, Inc. (Austin, Texas) |
| INVENTOR(S) | Frank Zeller (Austin, Texas) |
| ABSTRACT | The present invention relates to an energy absorbing composition comprising a core material and an appliqué material. The energy absorbing material may include a core material, such as an aluminum honeycomb or expanded polypropylene (EPP). The energy absorbing material may further comprise a protective material, which is applied to the core material to enhance durability of the energy absorbing material and increase the energy absorbing characteristics of the core The protective material may comprise external polyurethane, polyurea, or other suitable skin forming material and the protective material may be applied to the core material using any viable technique, including spraying or painting. The energy absorbing material of the present invention can withstand multiple impacts without significant loss to its energy absorbing qualities. The energy absorbing system meets or exceeds FMVSS 302 flammability specifications. |
| FILED | Tuesday, December 28, 2010 |
| APPL NO | 12/979892 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Stock material or miscellaneous articles 428/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790877 | Holwitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric A. Holwitt (San Antonio, Texas); Jonathan L. Kiel (Universal City, Texas); Veronica Franz Sorola (San Antonio, Texas) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Eric A. Holwitt (San Antonio, Texas); Jonathan L. Kiel (Universal City, Texas); Veronica Franz Sorola (San Antonio, Texas) |
| ABSTRACT | The solutions provided here use DNA aptamers and quantum dots for the detection of bacteria, viruses, proteins or other targets. An example of a method described here comprises: providing a complex of DNA complementary strands, one strand being an aptamer, having one strand covalently linked to a quantum dot, and having the other strand linked to a quencher; and contacting the complex of DNA complementary strands with a microorganism or components thereof, under conditions that permit binding of the aptamer with the microorganism or components thereof. |
| FILED | Wednesday, July 09, 2008 |
| APPL NO | 12/217833 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791227 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loon-Seng Tan (Centerville, Ohio); David Huabin Wang (Beavercreek, Ohio); Hilmar Koerner (Beavercreek, Ohio); Richard A. Vaia (Beavercreek, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); David Huabin Wang (Beavercreek, Ohio); Hilmar Koerner (Beavercreek, Ohio); Richard A. Vaia (Beavercreek, Ohio) |
| ABSTRACT | A crosslinked aromatic polyimide having shape memory properties and methods of making the same. The crosslinked aromatic polyimide comprises at least one aromatic diamine, at least one dianhydride monomer, and a tri(oxybenzene-amine) crosslinker. The crosslinked aromatic polyimide polymers and films possess superior shape memory properties at temperatures above 225° C. |
| FILED | Wednesday, July 11, 2012 |
| APPL NO | 13/546439 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/342 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791411 | Lozano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Paulo C. Lozano (Arlington, Massachusetts); Natalya Anna Brikner (Cambridge, Massachusetts); Chase Spenser Coffman (Cambridge, Massachusetts) |
| ABSTRACT | An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or room-temperature molten salt. The body can have a pore size gradient that decreases from the base of the body to the tip of the body, such that the at least one of an ionic liquid or room-temperature molten salt is capable of being transported through capillarity from the base to the tip. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/839064 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791707 | Bowler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nicola Bowler (Ames, Iowa); Tianming Chen (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Nicola Bowler (Ames, Iowa); Tianming Chen (Ames, Iowa) |
| ABSTRACT | A concentric coplanar capacitive sensor includes a charged central disc forming a first electrode, an outer annular ring coplanar with and outer to the charged central disc, the outer annular ring forming a second electrode, and a gap between the charged central disc and the outer annular ring. The first electrode and the second electrode may be attached to an insulative film. A method provides for determining transcapacitance between the first electrode and the second electrode and using the transcapacitance in a model that accounts for a dielectric test piece to determine inversely the properties of the dielectric test piece. |
| FILED | Monday, July 18, 2011 |
| APPL NO | 13/185156 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/226 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791718 | Clark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence T. Clark (Phoenix, Arizona); Nathan D. Hindman (Tempe, Arizona); Dan Wheeler Patterson (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Lawrence T. Clark (Phoenix, Arizona); Nathan D. Hindman (Tempe, Arizona); Dan Wheeler Patterson (Scottsdale, Arizona) |
| ABSTRACT | The disclosure relates generally to triple-redundant sequential state (TRSS) machines formed as integrated circuits on a semiconductor substrate, such as CMOS, and computerized methods and systems of designing the triple-redundant sequential state machines. Of particular focus in this disclosure are sequential state elements (SSEs) used to sample and hold bit states. The sampling and holding of bits states are synchronized by a clock signal thereby allowing for pipelining in the TRSS machines. In particular, the clock signal may oscillate between a first clock state and a second clock state to synchronize the operation of the SSE according to the timing provided by the clock states. The SSEs have a self-correcting mechanism to protect against radiation induced soft errors. The SSE may be provided in a pipeline circuit of a TRSS machine to receive and store a bit state of bit signal generated by combinational circuits within the pipeline circuit. |
| FILED | Monday, June 04, 2012 |
| APPL NO | 13/487859 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electronic digital logic circuitry 326/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791759 | Darwish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ali Darwish (Laurel, Maryland); Thomas J. Farm (Washington, District of Columbia); Mona Zaghloul (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia); The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Ali Darwish (Laurel, Maryland); Thomas J. Farm (Washington, District of Columbia); Mona Zaghloul (Bethesda, Maryland) |
| ABSTRACT | An amplifier for an integrated circuit has a plurality of ratioed current mirrors connected to each other in a stacked configuration. Each ratio mirror has at least two resistors and at least two bipolar transistors connected to each other via said at least two resistors. Each amplifying transistor, contains a capacitor, and potentially and inductor, to internally match the transistors that make up the amplifying stack. DC, harmonic and s-parameter simulations are performed to provide an optimal impedance for each of the stacked transistors to maximize the RF power output of each stacked layer and the amplifier. |
| FILED | Thursday, March 22, 2012 |
| APPL NO | 13/427311 |
| ART UNIT | 2843 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers 330/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792095 | Piorek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian D. Piorek (Santa Barbara, California); Carl D. Meinhart (Santa Barbara, California); Seung Joon Lee (Santa Barbara, California) |
| ASSIGNEE(S) | OndaVia, Inc. (Hayward, California) |
| INVENTOR(S) | Brian D. Piorek (Santa Barbara, California); Carl D. Meinhart (Santa Barbara, California); Seung Joon Lee (Santa Barbara, California) |
| ABSTRACT | Methods and apparatus for detection and/or analysis of gas phase analytes and chemical compounds. The apparatus can be formed with microfluidic cells containing a selected fluid that interacts with the analyte(s), wherein the fluid can selectively transition between a vapor phase and a liquid phase. During condensation of the fluid, the population of analytes present within the vapor phase region of the fluid can be transported into the liquid phase region of the fluid within the microfluidic cells. During evaporation of the fluid, the analytes can be substantially retained within liquid phase region of the fluid and within the cells. Repetitive cycling of this vapor/liquid exchange can provide a build-up of the analytes within the microfluidic cells where they can be detected/analyzed. |
| FILED | Friday, May 07, 2010 |
| APPL NO | 13/318983 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 2209/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792099 | Efimov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oleg M. Efimov (Thousand Oaks, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Oleg M. Efimov (Thousand Oaks, California) |
| ABSTRACT | A method and apparatus for measurement of individual phases of beams from a beam steering laser array relative to a reference laser beam. The disclosed method and apparatus is based on the use of a partially reflecting ellipsoidal reflector or dual paraboloidal reflector having two focal areas to make an image of the laser array located in one of the focal areas appear at the other focal area. Illumination of this image with a phase modulated beam from a reference laser coherent with the laser array allows the application of dithering techniques to measure individual phases of beams from array. Any laser beam in the array or a separate laser coherent with the laser array can be used as a reference beam. In addition, the partially reflecting ellipsoidal reflector or dual paraboloidal reflector can provide protection for the beam steering laser array from environmental impacts or damage. |
| FILED | Wednesday, December 21, 2011 |
| APPL NO | 13/332939 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/450 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792332 | Heckendorf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ryan Abel Heckendorf (Rochester, Minnesota); Kerry Christopher Imming (Rochester, Minnesota); John David Irish (Rochester, Minnesota); Ibrahim Abdel-Rahman Ouda (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ryan Abel Heckendorf (Rochester, Minnesota); Kerry Christopher Imming (Rochester, Minnesota); John David Irish (Rochester, Minnesota); Ibrahim Abdel-Rahman Ouda (Rochester, Minnesota) |
| ABSTRACT | A method and circuit for implementing lane shuffle for fault-tolerant communication links, and a design structure on which the subject circuit resides are provided. Shuffle hardware logic steers a set of virtual data lanes onto a set of physical optical lanes, steering around all lanes that are detected as bad during link initialization training. A mask status register is loaded with a mask of lane fail information during link training, which flags the bad lanes, if any. The shuffle hardware logic uses a shift template, where each position in the starting template is a value representing the corresponding lane position. The shift template is cascaded through a set of shifters controlled by the fail mask. |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/884389 |
| ART UNIT | 2469 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2602 (20130101) Original (OR) Class Wireless Communication Networks H04W 24/00 (20130101) H04W 24/08 (20130101) H04W 28/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792517 | Mo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shaomin Mo (Montville, New Jersey); John A. Gu (Rockaway, New Jersey); John A. Tranquilli, Jr. (Merrimack, New Hampshire); Joseph Farkas (Merrimack, New Hampshire); Ming Luo (Fairfax, Virginia); Reza Ghanadan (Berkeley Heights, New Jersey) |
| ASSIGNEE(S) | Collision Communications, Inc. (Peterborough, New Hampshire) |
| INVENTOR(S) | Shaomin Mo (Montville, New Jersey); John A. Gu (Rockaway, New Jersey); John A. Tranquilli, Jr. (Merrimack, New Hampshire); Joseph Farkas (Merrimack, New Hampshire); Ming Luo (Fairfax, Virginia); Reza Ghanadan (Berkeley Heights, New Jersey) |
| ABSTRACT | In the method for operating an interference multiple access communications system, wherein the improvement comprises the steps of employing a distributed scheduler within a Media Access Controller (MAC) for Multiuser Detection (MUD) enabled Mobile Ad-hoc Networks (MANETS) to increase spectral efficiency by increasing spectral use and providing a way to dynamically allocate virtual channels to achieve maximum channel reuse in different network topologies and different link patterns and to ameliorate any hidden or exposed node problems. |
| FILED | Wednesday, April 20, 2011 |
| APPL NO | 13/090435 |
| ART UNIT | 2464 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 74/0841 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792528 | Blick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert H. Blick (Madison, Wisconsin); Luke J. Mawst (Sun Prairie, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Robert H. Blick (Madison, Wisconsin); Luke J. Mawst (Sun Prairie, Wisconsin) |
| ABSTRACT | Disclosed are semiconductor microtube lasers including a semiconductor multilayer heterostructure. The multilayer heterostructure includes a substantially cylindrical optically active structure capable of light emission when under the influence of an applied electromagnetic field and a substantially cylindrical distributed feedback grating structure configured to provide optical feedback for a selected wavelength of light from the optically active region and to produce lasing action from the microtube when under the influence of an applied electromagnetic field. |
| FILED | Wednesday, May 09, 2012 |
| APPL NO | 13/467217 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/50.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792602 | Bernstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey Bernstein (Middleton, Massachusetts); Benjamin Vigoda (Winchester, Massachusetts); David Reynolds (Scarborough, Maine); Alexander Alexeyev (Gorham, Maine); William Bradley (Somerville, Massachusetts) |
| ASSIGNEE(S) | Analog Devices, Inc. (Norwood, Massachusetts) |
| INVENTOR(S) | Jeffrey Bernstein (Middleton, Massachusetts); Benjamin Vigoda (Winchester, Massachusetts); David Reynolds (Scarborough, Maine); Alexander Alexeyev (Gorham, Maine); William Bradley (Somerville, Massachusetts) |
| ABSTRACT | A processor implements a network of functional nodes and communication paths between the nodes. The processor includes a plurality of circuit implementations of the functional nodes of the processor; and a plurality of signal paths implementing the communication paths linking the circuit implementations of the nodes. At least some of the signal paths are configured to pass signal values represented according to temporal patterns of signal levels on the signal paths. The processor also includes a plurality of circuit components for conversion between a signal value represented as a signal level (e.g., voltage or current level) and a signal value represented as a temporal pattern. |
| FILED | Tuesday, February 22, 2011 |
| APPL NO | 13/032520 |
| ART UNIT | 2467 — Multiplex and VoIP |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1111 (20130101) H03M 13/6597 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792786 | Whelihan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David J. Whelihan (Framingham, Massachusetts); Scott M. Sawyer (Auburndale, Massachusetts); Jeffrey J. Hughes (Arlington, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David J. Whelihan (Framingham, Massachusetts); Scott M. Sawyer (Auburndale, Massachusetts); Jeffrey J. Hughes (Arlington, Massachusetts) |
| ABSTRACT | Data locality constraints are alleviated by a data processing system and method of reorganizing data. Multiple electronic components are configured to modulate a light beam on a shared photonic interconnect and to detect the data according to a global schedule to reorganize data across the multiple electronic components. By constructing data transfer patterns in a shared photonic interconnect, rather than in dedicated reorganization hardware, data is reorganized while in transit, greatly accelerating the reorganization of data, and reducing the amount of power-consuming hardware necessary to achieve the task. |
| FILED | Tuesday, May 22, 2012 |
| APPL NO | 13/477943 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Optical communications 398/48 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792976 | Gilja et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vikash Gilja (San Francisco, California); Paul Nuyujukian (Stanford, California); Cynthia A Chestek (Menlo Park, California); John P Cunningham (Saratoga, California); Byron M. Yu (San Jose, California); Stephen I Ryu (Menlo Park, California); Krishna V. Shenoy (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Vikash Gilja (San Francisco, California); Paul Nuyujukian (Stanford, California); Cynthia A Chestek (Menlo Park, California); John P Cunningham (Saratoga, California); Byron M. Yu (San Jose, California); Stephen I Ryu (Menlo Park, California); Krishna V. Shenoy (Palo Alto, California) |
| ABSTRACT | Artificial control of a prosthetic device is provided. A brain machine interface contains a mapping of neural signals and corresponding intention estimating kinematics (e.g. positions and velocities) of a limb trajectory. The prosthetic device is controlled by the brain machine interface. During the control of the prosthetic device, a modified brain machine interface is developed by modifying the vectors of the velocities defined in the brain machine interface. The modified brain machine interface includes a new mapping of the neural signals and the intention estimating kinematics that can now be used to control the prosthetic device using recorded neural brain signals from a user of the prosthetic device. In one example, the intention estimating kinematics of the original and modified brain machine interface includes a Kalman filter modeling velocities as intentions and positions as feedback. |
| FILED | Thursday, February 17, 2011 |
| APPL NO | 12/932070 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0476 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Original (OR) Class A61F 4/00 (20130101) A61F 2002/704 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793081 | Loverich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jacob Loverich (State College, Pennsylvania); Stephen J. Wenner (Port Matilda, Pennsylvania); Jeremy E. Frank (Pine Grove Mills, Pennsylvania) |
| ASSIGNEE(S) | KCF Technologies Inc (State College, Pennsylvania) |
| INVENTOR(S) | Jacob Loverich (State College, Pennsylvania); Stephen J. Wenner (Port Matilda, Pennsylvania); Jeremy E. Frank (Pine Grove Mills, Pennsylvania) |
| ABSTRACT | A improved method of monitoring a structure by mounting a sensor within a cavity of the structure to measure at least one of strain experienced by the structure and vibration experience by the structure. Mounting a wireless communication unit mounted within the structure and connecting the wireless communication unit to the sensor to receive data from the sensor and transmit the data to a receiver outside the structure. Mounting a power supply within the structure and connecting the power supply to the sensor and the wireless communication unit to supply necessary electrical power to the sensor and the communication unit. |
| FILED | Wednesday, July 06, 2011 |
| APPL NO | 13/176975 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/42 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793151 | DelZoppo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. DelZoppo (Cicero, New York); Eric Brown (Sherrill, New York); Matthew Sweeney (Baldwinsville, New York) |
| ASSIGNEE(S) | SRC, Inc. (North Syracuse, New York) |
| INVENTOR(S) | Robert J. DelZoppo (Cicero, New York); Eric Brown (Sherrill, New York); Matthew Sweeney (Baldwinsville, New York) |
| ABSTRACT | A method for characterizing risk using an adaptive risk analysis engine. Following a user request for a risk analysis, online and/or offline factual information is retrieved by the engine and is used to produce risk indicators. The risk indicators are mapped onto risk ontology to produce risk factors which are then used to assess the level of risk. Parameters for the likelihood, impact, and external threat of the risk are calculated, and a risk assessment report is produced for the user. |
| FILED | Friday, August 28, 2009 |
| APPL NO | 12/549843 |
| ART UNIT | 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0635 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793198 | Thomas |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Alan Thomas (King George, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Alan Thomas (King George, Virginia) |
| ABSTRACT | A semantic software agent and methods for designing and implementing the software agent and multi-agent systems, where the semantic software agent includes an interface adapter configured to receive instances of data collected and queries from an external source; a semantic repository configured to receive the instances and queries from the interface adapter; and an inference engine configured to receive the instance data from the semantic repository and to generate semantic inferences on the instances based on an ontology and semantic rules. An online simulation apparatus is also provided to generate actions and events for a simulation environment in real-time. |
| FILED | Wednesday, November 16, 2011 |
| APPL NO | 13/373746 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793211 | Marecki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Janusz Marecki (New York, New York); Mudhakar Srivatsa (White Plains, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Janusz Marecki (New York, New York); Mudhakar Srivatsa (White Plains, New York) |
| ABSTRACT | System, method and computer program product for modelling information sharing domains as Partially Observable Markov Decision Processes (POMDP), and that provides solutions that view the information sharing as a sequential process where the trustworthiness of the information recipients is monitored using data leakage detection mechanisms. In one embodiment, the system, method and computer program product performs (i) formulating information sharing decisions using Partially Observable Markov Decision Processes combined with a digital watermarking leakage detection mechanism, and (ii) deriving optimal information sharing strategies for the sender and optimal information leakage strategies for a recipient as a function of the efficacy of the underlying monitoring mechanism. By employing POMDPs in information sharing domains, users (senders) can maximize the expected reward of their data/information sharing actions. |
| FILED | Thursday, August 19, 2010 |
| APPL NO | 12/806686 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/62 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793241 | Koch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christoph E. Koch (Ithaca, New York); Yanif Ahmad (McClean, Virginia) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Christoph E. Koch (Ithaca, New York); Yanif Ahmad (McClean, Virginia) |
| ABSTRACT | A system and method for implementing incremental evaluation that is advantageous over nonincremental evaluation. The system and method incrementally maintain each individual aggregate value, for non-nested queries, using a constant amount of work. |
| FILED | Friday, June 25, 2010 |
| APPL NO | 13/379386 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/713 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793370 | Lane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rita A. Lane (San Diego, California); Eric Coolbaugh (San Diego, California); Robert Drew (Asheville, North Carolina); Alice Moore (San Diego, California); Jeffrey B. Lee (Lakeside, California); Walter M. Seay (Poway, California); Alan O. Peterson (La Mesa, California) |
| ASSIGNEE(S) | The United States of Amerca, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rita A. Lane (San Diego, California); Eric Coolbaugh (San Diego, California); Robert Drew (Asheville, North Carolina); Alice Moore (San Diego, California); Jeffrey B. Lee (Lakeside, California); Walter M. Seay (Poway, California); Alan O. Peterson (La Mesa, California) |
| ABSTRACT | A Communication Assets Survey and Mapping Tool can include a CAS data collection sub-module, a CASM database server, a CAM display sub-module, a CAM data sub-module and a MAP generator sub-module. The CAS data collection sub-module is capable of collecting communication asset data. The CASM database server is capable of receiving and storing communication asset data from said CAS data collection sub-module. The CAM display module is capable of transmitting data and interoperability communication gaps in a display format. The CAM data sub-module is capable of providing an interface between the CAM display sub-module and the CASM database server for the storage and retrieval of information regarding data sharing. The MAP generator sub-module is capable of generating a customized map image that can be displayed using the CAM display sub-module. |
| FILED | Wednesday, February 02, 2011 |
| APPL NO | 13/019381 |
| ART UNIT | 2448 — Computer Networks |
| CURRENT CPC | Transmission H04B 1/59 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 41/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793619 | Roe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marvin W. Roe (Slildell, Louisiana); Geary J. Layne (Superior, Colorado) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marvin W. Roe (Slildell, Louisiana); Geary J. Layne (Superior, Colorado) |
| ABSTRACT | A user control is provided for use with a multidimensional dataset that allows a user to graphically set the bounds for one or more of the dimensions of data selected from the dataset. The graphical user control includes a wireframe cube representing the extent of data in the dataset and a selector box within the data cube. A user can indicate a selected perspective and orientation of the data by selecting a portion of an edge of the selector box, and a visual indication of the selected perspective and orientation is provided. The user further can select a desired portion of the data by changing a size and/or a position of the selector box within the data cube. The graphical user control further includes a visual indicator representing the fourth dimension of the dataset which allows the user to identify and select a further subset of the data defined by the selector box. The graphical user control further includes one or more navigation buttons that allow the user to rotate a view around the selector box, the view reflecting the selected perspective and orientation of data in the dataset. |
| FILED | Wednesday, January 21, 2009 |
| APPL NO | 12/356656 |
| ART UNIT | 2173 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04815 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
08793791 — Methods for detecting and classifying signals transmitted over a radio frequency spectrum
| US 08793791 | Livsics et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eugene Livsics (Vienna, Virginia); Mark A McHenry (McLean, Virginia); Dmitry Dain (Herndon, Virginia); Karl Steadman (Arlington, Virginia); Olga Ritterbush (Arlington, Virginia) |
| ASSIGNEE(S) | Shared Spectrum Company (Vienna, Virginia) |
| INVENTOR(S) | Eugene Livsics (Vienna, Virginia); Mark A McHenry (McLean, Virginia); Dmitry Dain (Herndon, Virginia); Karl Steadman (Arlington, Virginia); Olga Ritterbush (Arlington, Virginia) |
| ABSTRACT | A method for classifying a signal is disclosed. The method can be used by a station or stations within a network to classify the signal as non-cooperative (NC) or a target signal. The method performs classification over channels within a frequency spectrum. The percentage of power above a first threshold is computed for a channel. Based on the percentage, a signal is classified as a narrowband signal. If the percentage indicates the absence of a narrowband signal, then a lower second threshold is applied to confirm the absence according to the percentage of power above the second threshold. The signal is classified as a narrowband signal or pre-classified as a wideband signal based on the percentage. Pre-classified wideband signals are classified as a wideband NC signal or target signal using spectrum masks. |
| FILED | Tuesday, November 01, 2011 |
| APPL NO | 13/286745 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Information security 726/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08789630 | Galloway et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevin C. Galloway (Somerville, Massachusetts); Jonathan E. Clark (Tallahassee, Florida); Daniel E. Koditschek (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees Of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kevin C. Galloway (Somerville, Massachusetts); Jonathan E. Clark (Tallahassee, Florida); Daniel E. Koditschek (Philadelphia, Pennsylvania) |
| ABSTRACT | According to one aspect, this invention provides an apparatus for varying the stiffness of a leg of a robotic system. The apparatus includes a compliant spine assembly including a compliant spine mounted for movement adjacent the leg and a rack coupled to the compliant spine. It also includes a motor assembly positioned to move the compliant spine of the compliant spine assembly with respect to the leg, the motor assembly including a gear engaging the rack of the compliant spine assembly and a motor coupled to drive the gear. The compliant spine of the compliant spine assembly is configured to vary the stiffness of the leg of the robotic system as it is moved by the motor assembly with respect to the leg. |
| FILED | Tuesday, August 02, 2011 |
| APPL NO | 13/196001 |
| ART UNIT | 3611 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Motor vehicles 180/8.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790317 | Olbricht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William L. Olbricht (Ithaca, New York); Keith B. Neeves (Philadelphia, Pennsylvania); Conor Foley (Ithaca, New York); Russell T. Mattews (Skaneateles, New York); W. Mark Saltzman (New Haven, Connecticut); Andrew Sawyer (New Haven, Connecticut) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Yale University (New Haven, Connecticut) |
| INVENTOR(S) | William L. Olbricht (Ithaca, New York); Keith B. Neeves (Philadelphia, Pennsylvania); Conor Foley (Ithaca, New York); Russell T. Mattews (Skaneateles, New York); W. Mark Saltzman (New Haven, Connecticut); Andrew Sawyer (New Haven, Connecticut) |
| ABSTRACT | An embodiment of the invention is directed to a microfabricated, silicon-based, Convection Enhanced Delivery (CED) device. The device comprises a silicon shank portion, at least one individual parylene channel disposed along at least a part of an entire length of the shank, wherein the channel has one or more dimensioned fluid exit ports disposed at one or more respective locations of the channel and a fluid (drug) input opening. The fluid input opening may be configured or adapted to be connected to a fluid reservoir and/or a pump and/or a meter and/or a valve or other suitable control device(s) or apparatus that supplies and/or delivers fluid (eg, a drug) to the microfabricated device. The device may have multiple channels disposed side by side or in different surfaces of the device. |
| FILED | Tuesday, February 12, 2008 |
| APPL NO | 12/525393 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/264 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790502 | Richter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christiaan Richter (Boston, Massachusetts); Latika Menon (Boston, Massachusetts); Ronald J. Willey (Dedham, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Christiaan Richter (Boston, Massachusetts); Latika Menon (Boston, Massachusetts); Ronald J. Willey (Dedham, Massachusetts) |
| ABSTRACT | A method of preparing titania nanotubes involves anodization of titanium in the presence of chloride ions and at low pH (1-7) in the absence of fluoride. The method leads to rapid production of titania nanotubes of about 25 nm diameter and high aspect ratio. The nanotubes can be organized into bundles and tightly packed parallel arrays. Inclusion of organic acids in the electrolyte solution leads to the incorporation into the nanotubes of up to 50 atom percent of carbon. In a two-stage method, a titanium anode is pre-patterned using a fluoride ion containing electrolyte and subsequently anodized in a chloride ion containing electrolyte to provide more evenly distributed nanotube arrays. The titania nanotubes have uses in composite materials, solar cells, hydrogen production, and as hydrogen sensors. |
| FILED | Thursday, February 21, 2008 |
| APPL NO | 12/527889 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790610 | Zhai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Lei Zhai (Oviedo, Florida); Jianhua Liu (Orlando, Florida); Jianhua Zou (Orlando, Florida); Anindarupa Chunder (Orlando, Florida) |
| ABSTRACT | A method of forming composite materials includes dispersing a conjugated material, a solvent for the conjugated material, and a plurality of carbon nanotubes (CNTs) or graphene including structures having an outer surface to form a dispersion. The solvent is evaporated from the dispersion to yield a CNT or graphene composite including a plurality of crystalline supramolecular structures having the conjugated material non-covalently secured to the outer surface of the CNT or the graphene including structure. The supramolecular structures have an average length which extends outward in a length direction from the outer surface of the CNT or graphene including structure, where the average length is greater than an average width of the supramolecular structures. |
| FILED | Tuesday, November 12, 2013 |
| APPL NO | 14/077711 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Chemistry of inorganic compounds 423/445.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790621 | Zhao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yan Zhao (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Yan Zhao (Ames, Iowa) |
| ABSTRACT | The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used, for example, to inhibit a virus or bacteria from binding to a host cell. The inhibition can be used in therapy for the flu, cancer, or AIDS. The CRM particles can be used, for example, to prepare metal nanoparticles or metal alloy nanoparticles, or they can be used in catalytic reactions. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/640698 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790814 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yanbo Wang (Fairborn, Ohio); Guorong Chen (Fairborn, Ohio); Zhenning Yu (Fairborn, Ohio); Bor Z. Jang (Centerville, Ohio); Aruna Zhamu (Centerville, Ohio) |
| ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Yanbo Wang (Fairborn, Ohio); Guorong Chen (Fairborn, Ohio); Zhenning Yu (Fairborn, Ohio); Bor Z. Jang (Centerville, Ohio); Aruna Zhamu (Centerville, Ohio) |
| ABSTRACT | An inorganic material based surface-mediated cell (SMC) comprising (a) a cathode comprising a non-carbon-based inorganic cathode active material having a surface area to capture and store lithium thereon; (b) an anode comprising an anode current collector alone or both an anode current collector and an anode active material; (c) a porous separator; (d) a lithium-containing electrolyte in physical contact with the two electrodes, wherein the cathode has a specific surface area no less than 100 m2/g which is in direct physical contact with said electrolyte to receive lithium ions therefrom or to provide lithium ions thereto; and (e) a lithium source. This inorganic SMC provides both high energy density and high power density not achievable by supercapacitors and lithium-ion cells. |
| FILED | Thursday, February 16, 2012 |
| APPL NO | 13/385366 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791073 | West et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jennifer L. West (Pearland, Texas); Ho-Wook Jun (Houston, Texas); Lakeshia J. Taite (Grove Hill, Alabama) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Jennifer L. West (Pearland, Texas); Ho-Wook Jun (Houston, Texas); Lakeshia J. Taite (Grove Hill, Alabama) |
| ABSTRACT | Peptide-modified polyurethanes comprising the reaction product of an isocyanate, a chain extender, and a peptide are provided. Also provided processes for making a peptide-modified polyurethane comprising: providing an isocyanate; providing a chain extender; providing a peptide; and allowing the isocyanate, chain extender, and peptide to react thereby forming the peptide-modified polyurethane, as well as methods for treating a subject comprising: providing a peptide-modified polyurethane that comprises the reaction product of an isocyanate, a chain extender, and a peptide; and administering the peptide-modified polyurethane to the subject. |
| FILED | Monday, May 16, 2005 |
| APPL NO | 11/129941 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Original (OR) Class A61K 38/17 (20130101) A61K 47/48192 (20130101) A61K 47/48215 (20130101) A61K 47/48715 (20130101) Peptides C07K 7/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/08 (20130101) C08G 18/6446 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791121 | Arora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paramjit S. Arora (White Plains, New York); Petra Tosovska (New York, New York); Danielle Guarracino (Princeton, New Jersey); Brooke Bullock (Leesville, South Carolina) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Paramjit S. Arora (White Plains, New York); Petra Tosovska (New York, New York); Danielle Guarracino (Princeton, New Jersey); Brooke Bullock (Leesville, South Carolina) |
| ABSTRACT | The present invention relates to oligooxopiperazines and their use. Methods for preparing oligooxopiperazines are also disclosed. |
| FILED | Monday, November 01, 2010 |
| APPL NO | 12/917176 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) Heterocyclic Compounds C07D 403/06 (20130101) C07D 403/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791239 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiao-Wen Shi (College Park, Maryland); Hsuan-Chen Wu (Greenbelt, Maryland); Gregory F. Payne (Hunt Valley, Maryland); William E. Bentley (St. Michaels, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Xiao-Wen Shi (College Park, Maryland); Hsuan-Chen Wu (Greenbelt, Maryland); Gregory F. Payne (Hunt Valley, Maryland); William E. Bentley (St. Michaels, Maryland) |
| ABSTRACT | Biofunctionalized fibers including a fiber platform and a histidine-tagged protein and, optionally, an antibody. Chitosan is a fiber useful as the fiber platform. The fiber platform may be treated with nickel or may be directly linked to the histidine-tagged protein e.g., histidine-tagged streptococcal IgG-binding protein, protein G, protein G3T, GFP or RFP. The resulting biofunctionalized fibers can be assembled into protein fiber assemblies by a variety of biofabrication methods. The fiber assemblies, e.g., in the form of woven fabrics, are useful for (i) antigen capture; (ii) immunoanalysis, and/or (iii) multiplexed analysis. In one fabrication, each fiber of a fiber assembly presents a specific antibody, and mixing and matching of fibers, for example by weaving of fabrics from various antibody-presenting fibers, allows for multiple antigens to be captured simultaneously for multiplexed analysis. |
| FILED | Tuesday, April 07, 2009 |
| APPL NO | 12/990981 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5169 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791285 | Santra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Swadeshmukul Santra (Orlando, Florida); James Turkson (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Swadeshmukul Santra (Orlando, Florida); James Turkson (Orlando, Florida) |
| ABSTRACT | An activatable nanoprobe is provided having a core component and an active agent associated with the core component via a bond configured to be cleaved upon exposure to an endogenous compound. |
| FILED | Monday, June 11, 2012 |
| APPL NO | 13/493815 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | Organic compounds 556/31 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791411 | Lozano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Paulo C. Lozano (Arlington, Massachusetts); Natalya Anna Brikner (Cambridge, Massachusetts); Chase Spenser Coffman (Cambridge, Massachusetts) |
| ABSTRACT | An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or room-temperature molten salt. The body can have a pore size gradient that decreases from the base of the body to the tip of the body, such that the at least one of an ionic liquid or room-temperature molten salt is capable of being transported through capillarity from the base to the tip. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/839064 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/288 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791599 | Joannopoulos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | John D. Joannopoulos (Belmont, Massachusetts); Aristeidis Karalis (Boston, Massachusetts); Marin Soljacic (Belmont, Massachusetts) |
| ABSTRACT | Described herein are embodiments of a first resonator with a quality factor, Q1, greater than 100, coupled to an energy source, generating an oscillating near field region, and a second resonator, with a quality factor, Q2, greater than 100, optionally coupled to an energy drain, and moving freely within the near field region of the first resonator. The first resonator and the second resonator may be coupled to transfer electromagnetic energy from said first resonator to said second resonator as the second resonator moves freely within the near field region. |
| FILED | Wednesday, December 30, 2009 |
| APPL NO | 12/649635 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 11/182 (20130101) Antennas, i.e Radio Aerials H01Q 9/04 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 5/005 (20130101) H02J 17/00 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 10/7005 (20130101) Y02T 10/7088 (20130101) Y02T 90/14 (20130101) Y02T 90/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791902 | Colgate et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | James Edward Colgate (Evanston, Illinois); Michael A. Peshkin (Evanston, Illinois) |
| ABSTRACT | A haptic device includes a substrate that is subjected to lateral motion such as lateral oscillation with one or more degrees of freedom together with modulation of a friction reducing oscillation in a manner that can create a shear force on the user's finger or on an object on the device. |
| FILED | Thursday, June 27, 2013 |
| APPL NO | 13/928611 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/156 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791985 | Grier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David G. Grier (New York, New York); Sang-Hyuk Lee (Albany, California); Fook C. Cheong (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | David G. Grier (New York, New York); Sang-Hyuk Lee (Albany, California); Fook C. Cheong (New York, New York) |
| ABSTRACT | In-line holography to create images of a specimen, such as one or more particles dispersed in a transparent medium. Analyzing these images with results from light scattering theory yields the particles' sizes with nanometer resolution, their refractive indexes to within one part in a thousand, and their three dimensional positions with nanometer resolution. This procedure can rapidly and directly characterize mechanical, optical and chemical properties of the specimen and its medium. |
| FILED | Thursday, October 30, 2008 |
| APPL NO | 12/740628 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0227 (20130101) Original (OR) Class G01N 15/1463 (20130101) G01N 2015/025 (20130101) G01N 2015/0038 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) G01P 5/20 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/0866 (20130101) G03H 2001/005 (20130101) G03H 2001/0033 (20130101) G03H 2001/0447 (20130101) G03H 2001/0825 (20130101) G03H 2240/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792169 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hanqing Jiang (Chandler, Arizona); Hongbin Yu (Chandler, Arizona); Cunjiang Yu (Champaign, Illinois); Kevin O'Brien (Menlo Park, California); Yong-Hang Zhang (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Hanqing Jiang (Chandler, Arizona); Hongbin Yu (Chandler, Arizona); Cunjiang Yu (Champaign, Illinois); Kevin O'Brien (Menlo Park, California); Yong-Hang Zhang (Scottsdale, Arizona) |
| ABSTRACT | Described herein are diffraction gratings and methods for the manufacture thereof. One method comprises applying a force to a substrate to strain the substrate, disposing a thin film on at least a portion of the substrate, and reducing the force applied to the substrate, thereby causing the thin film to buckle. |
| FILED | Tuesday, January 24, 2012 |
| APPL NO | 13/357269 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/566 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792367 | Nie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chun Nie (Nutley, New Jersey); Pei Liu (Forest Hills, New York); Thanasis Korakis (Brooklyn, New York); Elza Erkip (New York, New York); Shivendra S. Panwar (Freehold, New Jersey) |
| ASSIGNEE(S) | Polytechnic Institute of New York University (Brooklyn, New York) |
| INVENTOR(S) | Chun Nie (Nutley, New Jersey); Pei Liu (Forest Hills, New York); Thanasis Korakis (Brooklyn, New York); Elza Erkip (New York, New York); Shivendra S. Panwar (Freehold, New Jersey) |
| ABSTRACT | Cooperative communication is a technique that can be employed to meet the increased throughput needs of next generation WiMAX systems. In a cooperative scenario, multiple stations can jointly emulate the antenna elements of a multi-input multi-output system in a distributed fashion. A framework for a randomized distributed space-time coding (“R-DSTC”) technique in the emerging relay-assisted WiMAX network, and the development of a cooperative medium access control (“MAC”) layer protocol, called CoopMAX, for R-DSTC deployment in an IEEE 802.16 system, is described. The technique described couples the MAC layer with the physical (PHY) layer for performance optimization. The PHY layer yields significant diversity gain, while the MAC layer achieves a substantial end-to-end throughput gain. |
| FILED | Friday, January 21, 2011 |
| APPL NO | 13/010951 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/252 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793006 | Troian |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sandra M. Troian (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sandra M. Troian (Pasadena, California) |
| ABSTRACT | An apparatus and method of controllably stimulating the growth and evolution of 2D and 3D structures from a thin film mass transfer process such that complex devices can be designed and fabricated having engineered features of different heights and separation distances in a single or few process steps are provided. More specifically, the apparatus and method allows for the construction of engineered temperature gradient fields capable of controlling for, and taking into account, proximity effects during the growth and evolution of adjacent structures, which in turn allows for the production of technologically significant micro and nanoscale devices in a number of fields. |
| FILED | Wednesday, November 25, 2009 |
| APPL NO | 12/626239 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/98 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793496 | Burmester et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mike Burmester (Tallahassee, Florida); Breno de Medeiros (Tallahassee, Florida); Tri Van Le (Cupertino, California); Christy Chatmon (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University (Tallahassee, Florida) |
| INVENTOR(S) | Mike Burmester (Tallahassee, Florida); Breno de Medeiros (Tallahassee, Florida); Tri Van Le (Cupertino, California); Christy Chatmon (Tallahassee, Florida) |
| ABSTRACT | Embodiments of the invention may provide for systems and methods for secure authentication. The systems and methods may include receiving, by a constrained device, a random string transmitted from a server; determining, by the constrained device, a responsive output by evaluating a first deterministic function based upon the received random string, a locally generated string and a first private key stored on the constrained device; and transmitting at least one portion of the responsive output and the locally generated string from the constrained device to a server. The systems and methods may also include determining, by the server, a validation output by evaluating a second deterministic function based upon the random string, the locally generated string, and a second private key of a plurality of private keys stored on the server; and authenticating the constrained device based upon the server matching the transmitted at least one portion of the responsive output to at least a portion of the validation output. |
| FILED | Monday, August 20, 2007 |
| APPL NO | 11/841488 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/172 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08789372 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas Edward Johnson (Greer, South Carolina); Willy Steve Ziminsky (Simpsonville, South Carolina); William David York (Greer, South Carolina); Christian Xavier Stevenson (Inman, South Carolina) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Thomas Edward Johnson (Greer, South Carolina); Willy Steve Ziminsky (Simpsonville, South Carolina); William David York (Greer, South Carolina); Christian Xavier Stevenson (Inman, South Carolina) |
| ABSTRACT | The system may include a turbine engine. The turbine engine may include a fuel nozzle. The fuel nozzle may include an air path. The fuel nozzle may also include a fuel path such that the fuel nozzle is in communication with a combustion zone of the turbine engine. Furthermore, the fuel nozzle may include a resonator. The resonator may be disposed in the fuel nozzle directly adjacent to the combustion zone. |
| FILED | Wednesday, July 08, 2009 |
| APPL NO | 12/499777 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/725 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08789425 | Oh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hysitron Inc. (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | Hysitron Incorporated (Eden Prairie, Minnesota) |
| INVENTOR(S) | Yunje Oh (Medina, Minnesota); Edward Cyrankowski (Woodbury, Minnesota); Zhiwei Shan (Plymouth, Minnesota); Syed Amanula Syed Asif (Bloomington, Minnesota) |
| ABSTRACT | A micromachined or microelectromechanical system (MEMS) based push-to-pull mechanical transformer for tensile testing of micro-to-nanometer scale material samples including a first structure and a second structure. The second structure is coupled to the first structure by at least one flexible element that enables the second structure to be moveable relative to the first structure, wherein the second structure is disposed relative to the first structure so as to form a pulling gap between the first and second structures such that when an external pushing force is applied to and pushes the second structure in a tensile extension direction a width of the pulling gap increases so as to apply a tensile force to a test sample mounted across the pulling gap between a first sample mounting area on the first structure and a second sample mounting area on the second structure. |
| FILED | Tuesday, May 07, 2013 |
| APPL NO | 13/888959 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/774 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790082 | Merrill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gary B. Merrill (Orlando, Florida); Clinton Mayer (Jupiter, Florida) |
| ASSIGNEE(S) | Siemens Energy, Inc. (Orlando, Florida) |
| INVENTOR(S) | Gary B. Merrill (Orlando, Florida); Clinton Mayer (Jupiter, Florida) |
| ABSTRACT | A gas turbine blade (10) including a hollow mid-span snubber (16). The snubber is affixed to the airfoil portion (14) of the blade by a fastener (20) passing through an opening (24) cast into the surface (22) of the blade. The opening is defined during an investment casting process by a ceramic pedestal (38) which is positioned between a ceramic core (32) and a surrounding ceramic casting shell (48). The pedestal provides mechanical support for the ceramic core during both wax and molten metal injection steps of the investment casting process. |
| FILED | Monday, August 02, 2010 |
| APPL NO | 12/848456 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Fluid reaction surfaces 416/96.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790442 | Englund et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David J. Englund (Bovey, Minnesota); Mark Schlichting (Crawfordsville, Indiana); John Meehan (Conway, Arkansas); Jeremiah Crouch (Conway, Arkansas); Logan Wilson (Hot Springs, Arkansas) |
| ASSIGNEE(S) | Nu-Iron Technology LLC (Charlotte, North Carolina) |
| INVENTOR(S) | David J. Englund (Bovey, Minnesota); Mark Schlichting (Crawfordsville, Indiana); John Meehan (Conway, Arkansas); Jeremiah Crouch (Conway, Arkansas); Logan Wilson (Hot Springs, Arkansas) |
| ABSTRACT | A method of production of metallic iron nodules comprises assembling a hearth furnace having a moveable hearth comprising refractory material and having a conversion zone and a fusion zone, providing a hearth material layer comprising carbonaceous material on the refractory material, providing a layer of reducible material comprising and iron bearing material arranged in discrete portions over at least a portion of the hearth material layer, delivering oxygen gas into the hearth furnace to a ratio of at least 0.8:1 ponds of oxygen to pounds of iron in the reducible material to heat the conversion zone to a temperature sufficient to at least partially reduce the reducible material and to heat the fusion zone to a temperature sufficient to at least partially reduce the reducible material, and heating the reducible material to form one or more metallic iron nodules and slag. |
| FILED | Wednesday, September 29, 2010 |
| APPL NO | 13/499152 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/484 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790542 | Dibble et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dean C. Dibble (San Mateo, California); Aurelia Cheng (Berkeley, California); Anthe George (Berkeley, California) |
| ASSIGNEE(S) | Sandia Corporation (Livermore, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Dean C. Dibble (San Mateo, California); Aurelia Cheng (Berkeley, California); Anthe George (Berkeley, California) |
| ABSTRACT | The present invention provides for novel compositions and methods for recycling or recovering ionic liquid used in IL pretreated cellulose and/or lignocellulosic biomass (LBM). |
| FILED | Thursday, September 30, 2010 |
| APPL NO | 12/895771 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/182.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790546 | Schmidt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lanny D. Schmidt (Minneapolis, Minnesota); Paul J. Dauenhauer (Wisconsin Rapids, Wisconsin); Nick J. Degenstein (The Woodlands, Texas); Bradon J. Dreyer (Rockford, Michigan); Joshua L. Colby (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Lanny D. Schmidt (Minneapolis, Minnesota); Paul J. Dauenhauer (Wisconsin Rapids, Wisconsin); Nick J. Degenstein (The Woodlands, Texas); Bradon J. Dreyer (Rockford, Michigan); Joshua L. Colby (Minneapolis, Minnesota) |
| ABSTRACT | A method comprising contacting a carbon and hydrogen-containing solid fuel and a metal-based catalyst in the presence of oxygen to produce hydrogen gas and carbon monoxide gas, wherein the contacting occurs at a temperature sufficiently high to prevent char formation in an amount capable of stopping production of the hydrogen gas and the carbon monoxide gas is provided. In one embodiment, the metal-based catalyst comprises a rhodium-cerium catalyst. Embodiments further include a system for producing syngas. The systems and methods described herein provide shorter residence time and high selectivity for hydrogen and carbon monoxide. |
| FILED | Wednesday, March 05, 2008 |
| APPL NO | 12/528416 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compositions 252/373 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790615 | Viswanathan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tito Viswanathan (Little Rock, Arkansas) |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Tito Viswanathan (Little Rock, Arkansas) |
| ABSTRACT | A method of synthesizing carbon-magnetite nanocomposites. In one embodiment, the method includes the steps of (a) dissolving a first amount of an alkali salt of lignosulfonate in water to form a first solution, (b) heating the first solution to a first temperature, (c) adding a second amount of iron sulfate (FeSO4) to the first solution to form a second solution, (d) heating the second solution at a second temperature for a first duration of time effective to form a third solution of iron lignosulfonate, (e) adding a third amount of 1N sodium hydroxide (NaOH) to the third solution of iron lignosulfonate to form a fourth solution with a first pH level, (f) heating the fourth solution at a third temperature for a second duration of time to form a first sample, and (g) subjecting the first sample to a microwave radiation for a third duration of time effective to form a second sample containing a plurality of carbon-magnetite nanocomposites. |
| FILED | Tuesday, March 22, 2011 |
| APPL NO | 13/069097 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/632 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790791 | Cheruvu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Narayana S. Cheruvu (San Antonio, Texas); Ronghua Wei (San Antonio, Texas) |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas) |
| INVENTOR(S) | Narayana S. Cheruvu (San Antonio, Texas); Ronghua Wei (San Antonio, Texas) |
| ABSTRACT | The present disclosure relates to an oxidation resistant nanocrystalline coating and a method of forming an oxidation resistant nanocrystalline coating. An oxidation resistant coating comprising an MCrAl(Y) alloy may be deposited on a substrate, wherein M, includes iron, nickel, cobalt, or combinations thereof present greater than 50 wt % of the MCrAl(Y) alloy, chromium is present in the range of 15 wt % to 30 wt % of the MCrAl(Y) alloy, aluminum is present in the range of 6 wt % to 12 wt % of the MCrAl(Y) alloy and yttrium, is optionally present in the range of 0.1 wt % to 0.5 wt % of the MCrAl(Y) alloy. In addition, the coating may exhibit a grain size of 200 nm or less as deposited. |
| FILED | Thursday, April 15, 2010 |
| APPL NO | 12/760864 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Alloys C22C 19/05 (20130101) C22C 19/07 (20130101) C22C 30/00 (20130101) C22C 38/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/165 (20130101) Original (OR) Class C23C 14/345 (20130101) C23C 14/354 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790815 | Bucchi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert S. Bucchi (Lake Orion, Michigan); Daniel J. Casoli (Howell, Michigan); Kathleen M. Campbell (Troy, Michigan); Joseph Nicotina (Rochester, New York) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Robert S. Bucchi (Lake Orion, Michigan); Daniel J. Casoli (Howell, Michigan); Kathleen M. Campbell (Troy, Michigan); Joseph Nicotina (Rochester, New York) |
| ABSTRACT | A battery cell tab is described. The battery cell tab is anodized on one end and has a metal coating on the other end. Battery cells and methods of making battery cell tabs are also described. |
| FILED | Thursday, January 20, 2011 |
| APPL NO | 13/009889 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/24 (20130101) H01M 2/30 (20130101) Original (OR) Class H01M 2/32 (20130101) H01M 2/0212 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790902 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven D. Brown (Knoxville, Tennessee); Shihui Yang (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Batelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Steven D. Brown (Knoxville, Tennessee); Shihui Yang (Knoxville, Tennessee) |
| ABSTRACT | The present invention provides genetically modified strains of microorganisms that display enhanced tolerance to stress and/or inhibitors such as sodium acetate and vanillin. The enhanced tolerance can be achieved by increasing the expression of a protein of the Sm-like superfamily such as a bacterial Hfq protein and a fungal Sm or Lsm protein. Further, the present invention provides methods of producing alcohol from biomass materials by using the genetically modified microorganisms of the present invention. |
| FILED | Monday, August 20, 2012 |
| APPL NO | 13/589709 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790957 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bo Li (San Jose, California); David Smith (Campbell, California); Peter Cousins (Menlo Park, California) |
| ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
| INVENTOR(S) | Bo Li (San Jose, California); David Smith (Campbell, California); Peter Cousins (Menlo Park, California) |
| ABSTRACT | Methods of fabricating back-contact solar cells and devices thereof are described. A method of fabricating a back-contact solar cell includes forming an N-type dopant source layer and a P-type dopant source layer above a material layer disposed above a substrate. The N-type dopant source layer is spaced apart from the P-type dopant source layer. The N-type dopant source layer and the P-type dopant source layer are heated. Subsequently, a trench is formed in the material layer, between the N-type and P-type dopant source layers. |
| FILED | Friday, December 17, 2010 |
| APPL NO | 12/972247 |
| ART UNIT | 1758 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/98 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791037 | Berchtold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kathryn A. Berchtold (Los Alamos, New Mexico); Jennifer S. Young (Los Alamos, New Mexico) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Kathryn A. Berchtold (Los Alamos, New Mexico); Jennifer S. Young (Los Alamos, New Mexico) |
| ABSTRACT | A method of making ceramic membranes, and the ceramic membranes so formed, comprising combining a ceramic precursor with an organic or inorganic comonomer, forming the combination as a thin film on a substrate, photopolymerizing the thin film, and pyrolyzing the photopolymerized thin film. |
| FILED | Thursday, June 11, 2009 |
| APPL NO | 12/482718 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791396 | Burns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Burns (Houston, Texas); Charles R. Goodwin (League City, Texas) |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | David Burns (Houston, Texas); Charles R. Goodwin (League City, Texas) |
| ABSTRACT | A heating system for a subsurface formation includes a conduit located in a first opening in the subsurface formation. Three electrical conductors are located in the conduit. A return conductor is located inside the conduit. The return conductor is electrically coupled to the ends of the electrical conductors distal from the surface of the formation. Insulation is located inside the conduit. The insulation electrically insulates the three electrical conductors, the return conductor, and the conduit from each other. |
| FILED | Friday, April 18, 2008 |
| APPL NO | 12/106065 |
| ART UNIT | 3742 — Organic Chemistry |
| CURRENT CPC | Electric heating 219/542 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791426 | Elmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John W. Elmer (Danville, California); Alan T. Teruya (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | John W. Elmer (Danville, California); Alan T. Teruya (Livermore, California) |
| ABSTRACT | A system for analyzing an electron beam including a circular electron beam diagnostic sensor adapted to receive the electron beam, the circular electron beam diagnostic sensor having a central axis; an annular sensor structure operatively connected to the circular electron beam diagnostic sensor, wherein the sensor structure receives the electron beam; a system for sweeping the electron beam radially outward from the central axis of the circular electron beam diagnostic sensor to the annular sensor structure wherein the electron beam is intercepted by the annular sensor structure; and a device for measuring the electron beam that is intercepted by the annular sensor structure. |
| FILED | Monday, November 01, 2010 |
| APPL NO | 12/917028 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/2914 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/244 (20130101) Original (OR) Class H01J 2237/24405 (20130101) H01J 2237/24542 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792158 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jian Liu (Sunnyvale, California); Peng Wan (Fremont, California); Lihmei Yang (Santa Clara, California) |
| ASSIGNEE(S) | PolarOnyx, Inc. (San Jose, California) |
| INVENTOR(S) | Jian Liu (Sunnyvale, California); Peng Wan (Fremont, California); Lihmei Yang (Santa Clara, California) |
| ABSTRACT | Methods and systems for generating femtosecond fiber laser pulses are disclose, including generating a signal laser pulse from a seed laser oscillator; using a first amplifier stage comprising an input and an output, wherein the signal laser pulse is coupled into the input of the first stage amplifier and the output of the first amplifier stage emits an amplified and stretched signal laser pulse; using an amplifier chain comprising an input and an output, wherein the amplified and stretched signal laser pulse from the output of the first amplifier stage is coupled into the input of the amplifier chain and the output of the amplifier chain emits a further amplified, stretched signal laser pulse. Other embodiments are described and claimed. |
| FILED | Friday, April 20, 2012 |
| APPL NO | 13/452817 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/337.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08790639 | Donovan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David M. Donovan (Baltimore, Maryland); Jinzhe Mao (Crofton, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | David M. Donovan (Baltimore, Maryland); Jinzhe Mao (Crofton, Maryland) |
| ABSTRACT | Peptidoglycan hydrolases are an effective new source of antimicrobials. A chimeric fusion protein of the Ply187 endopeptidase domain and LysK SH3b cell wall binding domain is a potent agent against Staphylococcus aureus in three functional assays. |
| FILED | Wednesday, March 28, 2012 |
| APPL NO | 13/432758 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790875 | Khatib |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hasan Khatib (Fitchburg, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hasan Khatib (Fitchburg, Wisconsin) |
| ABSTRACT | Single nucleotide polymorphic sites of the bovine HSP genes are associated with improved fertilization rate and/or improved embryo survival rate in cattle. Nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods based on these SNPs are disclosed. |
| FILED | Wednesday, August 01, 2012 |
| APPL NO | 13/563750 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791105 | Coetzee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Johann F. Coetzee (Cambridge, Iowa); Stanley P. Kukanich (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhatten, Kansas) |
| INVENTOR(S) | Johann F. Coetzee (Cambridge, Iowa); Stanley P. Kukanich (Manhattan, Kansas) |
| ABSTRACT | Methods of improving performance, increasing weight gain, and decreasing incidence of disease in ruminant and pre-ruminant animals, such as cattle, after undergoing painful processing procedures, such as castration and dehorning, are provided. Veterinary formulations for use in methods of the invention are also provided. The formulations comprise a compound selected from the group consisting of meloxicam, gabapentin, the pharmaceutically acceptable salts thereof, and combinations thereof. Methods of treating pathological pain in cattle are also provided. |
| FILED | Thursday, July 14, 2011 |
| APPL NO | 13/810117 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 17/00 (20130101) Fodder A23K 1/165 (20130101) A23K 1/1646 (20130101) A23K 1/1813 (20130101) A23K 1/1893 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/5415 (20130101) Original (OR) Class A61K 31/5415 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791327 | Browse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John A. Browse (Palouse, Washington); James G. Wallis (Moscow, Idaho); Jennifer L. Watts (Moscow, Idaho) |
| ASSIGNEE(S) | Washington State University Research Foundation (Pullman, Washington) |
| INVENTOR(S) | John A. Browse (Palouse, Washington); James G. Wallis (Moscow, Idaho); Jennifer L. Watts (Moscow, Idaho) |
| ABSTRACT | The amino acid and nucleic acid sequences of a Δ5-desaturase enzyme and a Δ8-desaturase enzyme are disclosed. The nucleic acid sequences can be used to design recombinant DNA constructs and vectors. These vectors can then be used to transform various organisms, including for example, plants and yeast. The transformed organisms will then produce polyunsaturated fatty acids. The amino acid sequences are useful for generating enzyme-specific antibodies that are useful for identifying the desaturases. |
| FILED | Monday, February 27, 2012 |
| APPL NO | 13/406248 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/281 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08789629 | Parness et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aaron Parness (Los Angeles, California); Clifford F. McKenzie (Eagle Springs, North Carolina) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Aaron Parness (Los Angeles, California); Clifford F. McKenzie (Eagle Springs, North Carolina) |
| ABSTRACT | A terrain traversing device includes an annular rotor element with a plurality of co-planar microspine hooks arranged on the periphery of the annular rotor element. Each microspine hook has an independently flexible suspension configuration that permits the microspine hook to initially engage an irregularity in a terrain surface at a preset initial engagement angle and subsequently engage the irregularity with a continuously varying engagement angle when the annular rotor element is rotated for urging the terrain traversing device to traverse a terrain surface. |
| FILED | Friday, September 07, 2012 |
| APPL NO | 13/606885 |
| ART UNIT | 3611 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 9/12 (20130101) B60B 15/025 (20130101) Original (OR) Class B60B 2900/721 (20130101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2200/46 (20130101) B60Y 2200/47 (20130101) B60Y 2200/48 (20130101) Motor Vehicles; Trailers B62D 61/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790773 | Dudley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth L. Dudley (Newport News, Virginia); Holly A Elliott (Newport News, Virginia); John W. Connell (Yorktown, Virginia); Joseph G. Smith (Smithfield, Virginia); Sayata Ghose (Newport News, Virginia); Kent A. Watson (New Kent, Virginia); Donavon Mark Delozier (Disputanta, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth L. Dudley (Newport News, Virginia); Holly A Elliott (Newport News, Virginia); John W. Connell (Yorktown, Virginia); Joseph G. Smith (Smithfield, Virginia); Sayata Ghose (Newport News, Virginia); Kent A. Watson (New Kent, Virginia); Donavon Mark Delozier (Disputanta, Virginia) |
| ABSTRACT | A dielectric material includes a network of nanosubstrates, such as but not limited to nanotubes, nanosheets, or other nanomaterials or nanostructures, a polymer base material or matrix, and nanoparticles constructed at least partially of an elemental metal. The network has a predetermined nanosubstrate loading percentage by weight with respect to a total weight of the dielectric material, and a preferential or predetermined longitudinal alignment with respect to an orientation of an incident electrical field. A method of forming the dielectric material includes depositing the metal-based nanoparticles onto the nanosubstrates and subsequently mixing these with a polymer matrix. Once mixed, alignment can be achieved by melt extrusion or a similar mechanical shearing process. Alignment of the nanosubstrate may be in horizontal or vertical direction with respect to the orientation of an incident electrical field. |
| FILED | Wednesday, July 16, 2008 |
| APPL NO | 12/174360 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/323 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791353 | Paik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jong-Ah Paik (Pasadena, California); Thierry Caillat (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Jong-Ah Paik (Pasadena, California); Thierry Caillat (Pasadena, California) |
| ABSTRACT | Alumina as a sublimation suppression barrier for a Zintl thermoelectric material in a thermoelectric power generation device operating at high temperature, e.g. at or above 1000K, is disclosed. The Zintl thermoelectric material may comprise Yb14MnSb11. The alumina may be applied as an adhesive paste dried and cured on a substantially oxide free surface of the Zintl thermoelectric material and polished to a final thickness. The sublimation suppression barrier may be finalized by baking out the alumina layer on the Zintl thermoelectric material until it becomes substantially clogged with ytterbia. |
| FILED | Friday, March 12, 2010 |
| APPL NO | 12/723570 |
| ART UNIT | 1758 — Organic Chemistry |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/18 (20130101) Original (OR) Class H01L 35/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791707 | Bowler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nicola Bowler (Ames, Iowa); Tianming Chen (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Nicola Bowler (Ames, Iowa); Tianming Chen (Ames, Iowa) |
| ABSTRACT | A concentric coplanar capacitive sensor includes a charged central disc forming a first electrode, an outer annular ring coplanar with and outer to the charged central disc, the outer annular ring forming a second electrode, and a gap between the charged central disc and the outer annular ring. The first electrode and the second electrode may be attached to an insulative film. A method provides for determining transcapacitance between the first electrode and the second electrode and using the transcapacitance in a model that accounts for a dielectric test piece to determine inversely the properties of the dielectric test piece. |
| FILED | Monday, July 18, 2011 |
| APPL NO | 13/185156 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/226 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08790636 | Centanni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John M. Centanni (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ASSIGNEE(S) | Stratatech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | John M. Centanni (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides. |
| FILED | Wednesday, January 04, 2012 |
| APPL NO | 13/343314 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08790814 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yanbo Wang (Fairborn, Ohio); Guorong Chen (Fairborn, Ohio); Zhenning Yu (Fairborn, Ohio); Bor Z. Jang (Centerville, Ohio); Aruna Zhamu (Centerville, Ohio) |
| ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Yanbo Wang (Fairborn, Ohio); Guorong Chen (Fairborn, Ohio); Zhenning Yu (Fairborn, Ohio); Bor Z. Jang (Centerville, Ohio); Aruna Zhamu (Centerville, Ohio) |
| ABSTRACT | An inorganic material based surface-mediated cell (SMC) comprising (a) a cathode comprising a non-carbon-based inorganic cathode active material having a surface area to capture and store lithium thereon; (b) an anode comprising an anode current collector alone or both an anode current collector and an anode active material; (c) a porous separator; (d) a lithium-containing electrolyte in physical contact with the two electrodes, wherein the cathode has a specific surface area no less than 100 m2/g which is in direct physical contact with said electrolyte to receive lithium ions therefrom or to provide lithium ions thereto; and (e) a lithium source. This inorganic SMC provides both high energy density and high power density not achievable by supercapacitors and lithium-ion cells. |
| FILED | Thursday, February 16, 2012 |
| APPL NO | 13/385366 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08792158 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jian Liu (Sunnyvale, California); Peng Wan (Fremont, California); Lihmei Yang (Santa Clara, California) |
| ASSIGNEE(S) | PolarOnyx, Inc. (San Jose, California) |
| INVENTOR(S) | Jian Liu (Sunnyvale, California); Peng Wan (Fremont, California); Lihmei Yang (Santa Clara, California) |
| ABSTRACT | Methods and systems for generating femtosecond fiber laser pulses are disclose, including generating a signal laser pulse from a seed laser oscillator; using a first amplifier stage comprising an input and an output, wherein the signal laser pulse is coupled into the input of the first stage amplifier and the output of the first amplifier stage emits an amplified and stretched signal laser pulse; using an amplifier chain comprising an input and an output, wherein the amplified and stretched signal laser pulse from the output of the first amplifier stage is coupled into the input of the amplifier chain and the output of the amplifier chain emits a further amplified, stretched signal laser pulse. Other embodiments are described and claimed. |
| FILED | Friday, April 20, 2012 |
| APPL NO | 13/452817 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/337.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08793081 | Loverich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jacob Loverich (State College, Pennsylvania); Stephen J. Wenner (Port Matilda, Pennsylvania); Jeremy E. Frank (Pine Grove Mills, Pennsylvania) |
| ASSIGNEE(S) | KCF Technologies Inc (State College, Pennsylvania) |
| INVENTOR(S) | Jacob Loverich (State College, Pennsylvania); Stephen J. Wenner (Port Matilda, Pennsylvania); Jeremy E. Frank (Pine Grove Mills, Pennsylvania) |
| ABSTRACT | A improved method of monitoring a structure by mounting a sensor within a cavity of the structure to measure at least one of strain experienced by the structure and vibration experience by the structure. Mounting a wireless communication unit mounted within the structure and connecting the wireless communication unit to the sensor to receive data from the sensor and transmit the data to a receiver outside the structure. Mounting a power supply within the structure and connecting the power supply to the sensor and the wireless communication unit to supply necessary electrical power to the sensor and the communication unit. |
| FILED | Wednesday, July 06, 2011 |
| APPL NO | 13/176975 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/42 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08790871 | Spinale et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francis G. Spinale (Charleston, South Carolina); Robert E. Stroud (Mt. Pleasant, South Carolina); Michael R. Zile (Charleston, South Carolina) |
| ASSIGNEE(S) | MUSC Foundation for Research Development (Charleston, South Carolina) |
| INVENTOR(S) | Francis G. Spinale (Charleston, South Carolina); Robert E. Stroud (Mt. Pleasant, South Carolina); Michael R. Zile (Charleston, South Carolina) |
| ABSTRACT | Disclosed herein are methods of detecting and predicting diastolic heart failure and predicting congestive heart failure comprise protease and protease inhibitor profiling. |
| FILED | Tuesday, April 24, 2007 |
| APPL NO | 12/299999 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 2333/96486 (20130101) G01N 2800/50 (20130101) G01N 2800/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08791092 | Bitan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gal Bitan (Los Angeles, California); Akila Shanmugam (Allen, Texas); Aleksey Lomakin (Swampscott, Massachusetts); Thomas Schrader (Mettmann, Germany); Frank Gerrit Klarner (Bochum, Germany); Peter Talbiersky (Krems, Austria); Jolanta Polkowska (Essen, Germany); Frank Bastkowski (Braunschweig, Germany); Sharmistha Sinha (Ames, Iowa); Sally Frautschy (Santa Monica, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); Massachusetts Institute of Technology (Cambridge, Massachusetts); Universitat Duisburg-Essen (Essen, Germany) |
| INVENTOR(S) | Gal Bitan (Los Angeles, California); Akila Shanmugam (Allen, Texas); Aleksey Lomakin (Swampscott, Massachusetts); Thomas Schrader (Mettmann, Germany); Frank Gerrit Klarner (Bochum, Germany); Peter Talbiersky (Krems, Austria); Jolanta Polkowska (Essen, Germany); Frank Bastkowski (Braunschweig, Germany); Sharmistha Sinha (Ames, Iowa); Sally Frautschy (Santa Monica, California) |
| ABSTRACT | This invention provides novel compositions to inhibit the aggregation of amyloid proteins. In various embodiments the compositions comprise a molecular tweezers that binds lysine and/or arginine and thereby inhibits the aggregation of amyloidogenic proteins. |
| FILED | Friday, March 05, 2010 |
| APPL NO | 13/203962 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/107 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08791239 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiao-Wen Shi (College Park, Maryland); Hsuan-Chen Wu (Greenbelt, Maryland); Gregory F. Payne (Hunt Valley, Maryland); William E. Bentley (St. Michaels, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Xiao-Wen Shi (College Park, Maryland); Hsuan-Chen Wu (Greenbelt, Maryland); Gregory F. Payne (Hunt Valley, Maryland); William E. Bentley (St. Michaels, Maryland) |
| ABSTRACT | Biofunctionalized fibers including a fiber platform and a histidine-tagged protein and, optionally, an antibody. Chitosan is a fiber useful as the fiber platform. The fiber platform may be treated with nickel or may be directly linked to the histidine-tagged protein e.g., histidine-tagged streptococcal IgG-binding protein, protein G, protein G3T, GFP or RFP. The resulting biofunctionalized fibers can be assembled into protein fiber assemblies by a variety of biofabrication methods. The fiber assemblies, e.g., in the form of woven fabrics, are useful for (i) antigen capture; (ii) immunoanalysis, and/or (iii) multiplexed analysis. In one fabrication, each fiber of a fiber assembly presents a specific antibody, and mixing and matching of fibers, for example by weaving of fabrics from various antibody-presenting fibers, allows for multiple antigens to be captured simultaneously for multiplexed analysis. |
| FILED | Tuesday, April 07, 2009 |
| APPL NO | 12/990981 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5169 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 08793151 | DelZoppo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. DelZoppo (Cicero, New York); Eric Brown (Sherrill, New York); Matthew Sweeney (Baldwinsville, New York) |
| ASSIGNEE(S) | SRC, Inc. (North Syracuse, New York) |
| INVENTOR(S) | Robert J. DelZoppo (Cicero, New York); Eric Brown (Sherrill, New York); Matthew Sweeney (Baldwinsville, New York) |
| ABSTRACT | A method for characterizing risk using an adaptive risk analysis engine. Following a user request for a risk analysis, online and/or offline factual information is retrieved by the engine and is used to produce risk indicators. The risk indicators are mapped onto risk ontology to produce risk factors which are then used to assess the level of risk. Parameters for the likelihood, impact, and external threat of the risk are calculated, and a risk assessment report is produced for the user. |
| FILED | Friday, August 28, 2009 |
| APPL NO | 12/549843 |
| ART UNIT | 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0635 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08791044 | Varma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rajender S. Varma (Cincinnati, Ohio); Babita Baruwati (Bangalore, India); Jurate Virkutyte (Cincinnati, Ohio) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Rajender S. Varma (Cincinnati, Ohio); Babita Baruwati (Bangalore, India); Jurate Virkutyte (Cincinnati, Ohio) |
| ABSTRACT | Methods for preparing and using a photocatalyst are described. The catalyst is prepared by oxidation of a metal salt which has been doped in situ to form a photocatalyst active in visible light. The photocatalyst is used for degrading toxic and irritating compounds and infectious agents. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/662742 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08792243 | Babcock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raymond F. Babcock (Stewartville, Minnesota); Michael A. Boraas (Zumbrota, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Raymond F. Babcock (Stewartville, Minnesota); Michael A. Boraas (Zumbrota, Minnesota) |
| ABSTRACT | Carriage chassis for installation of a component assembly in a support structure. The support structure includes a power connector in a connector housing. The carriage chassis includes: rails adapted to receive a component assembly and a safety cover. One of the rails includes a tri-lobed torsion stop that includes a first lobe configured to contact the connector housing when no safety cover is installed, preventing a component assembly from coupling with power; a second lobe configured to receive contact from a displacement member of a safety cover, rotating the tri-lobed torsion stop; and a third lobe configured to provide contact to the displacement member when the safety cover is installed and a component assembly is coupled with power. The third lobe and the first lobe prevent removal of the safety cover when a component assembly is coupled with the power connector. |
| FILED | Wednesday, June 20, 2012 |
| APPL NO | 13/527791 |
| ART UNIT | 2846 — Optics |
| CURRENT CPC | Electricity: Electrical systems and devices 361/727 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08790275 | Parks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas R. Parks (Hermosa Beach, California); Ray E. Clouse (St. Louis, Missouri) |
| ASSIGNEE(S) | Given Imaging (Los Angeles) LLC (Yogneam, Israel) |
| INVENTOR(S) | Thomas R. Parks (Hermosa Beach, California); Ray E. Clouse (St. Louis, Missouri) |
| ABSTRACT | A system and methods that provide for visualization and/or characterization of manometry data. Visual representations of pressure information represent pressure information measured over time by sensors positioned within an organism. Markers may be provided on the visual representations. Using the system and methods described herein, various characteristics of an organism and/or events that occur within the organism may be determined. |
| FILED | Friday, May 13, 2005 |
| APPL NO | 11/129030 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/037 (20130101) Original (OR) Class A61B 5/053 (20130101) A61B 5/145 (20130101) A61B 2562/043 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 29, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140729.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page