FedInvent™ Patents
Patent Details for Tuesday, September 23, 2014
This page was updated on Monday, March 27, 2023 at 04:04 AM GMT
Department of Health and Human Services (HHS)
US 08839657 | Siegel |
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FUNDED BY |
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APPLICANT(S) | Jonathan H. Siegel (Skokie, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Jonathan H. Siegel (Skokie, Illinois) |
ABSTRACT | An acoustic probe calibration system includes a waveguide and a moveable piston. The waveguide extends from a front end to an opposite back end along a longitudinal axis and defines a cavity extending from the front end to the back end. The piston is disposed within the cavity of the waveguide and is configured to move within the cavity of the waveguide along the longitudinal axis of the waveguide. An acoustic probe is inserted into the waveguide to define an interior chamber between the acoustic probe and the piston. The acoustic probe determines pressure responses to acoustic stimuli inside the interior chamber. The piston is moveable to a plurality of different positions within the waveguide to change a size of the interior chamber such that the acoustic probe can determine the pressure responses within the varying-size interior chamber. |
FILED | Tuesday, May 15, 2012 |
APPL NO | 13/471941 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/30 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08839672 | Emelianov et al. |
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FUNDED BY |
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APPLICANT(S) | Stanislav Emelianov (Austin, Texas); Jimmy Su (Austin, Texas); Bo Wang (Austin, Texas); Andrei Karpiouk (Austin, Texas); Yun-Sheng Chen (Austin, Texas); Wolfgang Frey (Austin, Texas); Richard Bouchard (Austin, Texas); Kimberly Homan (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Stanislav Emelianov (Austin, Texas); Jimmy Su (Austin, Texas); Bo Wang (Austin, Texas); Andrei Karpiouk (Austin, Texas); Yun-Sheng Chen (Austin, Texas); Wolfgang Frey (Austin, Texas); Richard Bouchard (Austin, Texas); Kimberly Homan (Austin, Texas) |
ABSTRACT | Methods of combined ultrasound and photoacoustic imaging are provided. In some embodiments, the methods may be used to determine the location or positioning of a metal object in a sample. In other embodiments, the methods may be used to determine the composition of a sample surrounding a metal object. Other methods are also provided. |
FILED | Wednesday, October 19, 2011 |
APPL NO | 13/277074 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Measuring and testing 073/606 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840546 | Truong et al. |
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FUNDED BY |
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APPLICANT(S) | Stephanie L. Truong (San Francisco, California); Vandana Jain (Navi Mumbai, India); Michael Yung Peng (Laguna Niguel, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Stephanie L. Truong (San Francisco, California); Vandana Jain (Navi Mumbai, India); Michael Yung Peng (Laguna Niguel, California) |
ABSTRACT | A system for illuminating a body orifice includes: a frustoconical optical waveguide speculum includes a distal end, a proximal end wider than the distal end, an at least partially circumferential body wall having a bore passing between the proximal and distal ends of the speculum; and a base that couples to the speculum and receives a light source such that the speculum is configured to propagate light from the light source along the body wall. In a preferred embodiment, the body wall defines between an inner and outer surface of the body wall a fluidic channel configured to delivery fluid to the distal end of the speculum and a suction channel configured to drain fluid from distal end of the speculum. |
FILED | Wednesday, June 01, 2011 |
APPL NO | 13/150915 |
ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/227 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840565 | Keefe |
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FUNDED BY |
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APPLICANT(S) | Douglas H. Keefe (Omaha, Nebraska) |
ASSIGNEE(S) | Sonicom, Inc. (Omaha, Nebraska) |
INVENTOR(S) | Douglas H. Keefe (Omaha, Nebraska) |
ABSTRACT | A test battery method and system for use in assessing auditory function (e.g., the screening or diagnosis of impairments, fitting of hearing aids, etc.) is provided which performs one or more auditory tests including, for example, an acoustic reflectance test. Such an acoustic reflectance test may be a reflectance tympanometry test that includes a feedback system to control static pressure in the ear canal. Such acoustic reflectance tests may be used alone or in combination with one or more other auditory tests. Further, for example, such a battery of tests may include middle-ear muscle reflex tests in combination with one or more other auditory or hearing tests. |
FILED | Wednesday, August 08, 2012 |
APPL NO | 13/569849 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/121 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840566 | Seibel et al. |
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FUNDED BY |
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APPLICANT(S) | Eric J. Seibel (Seattle, Washington); Richard S. Johnston (Sammamish, Washington); Charles David Melville (Issaquah, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Eric J. Seibel (Seattle, Washington); Richard S. Johnston (Sammamish, Washington); Charles David Melville (Issaquah, Washington) |
ABSTRACT | A catheter having an imaging device on its distal end serves as a guidewire for cannula tools, enabling the tools to be advanced to a desired site in a patient's body. One exemplary embodiment of such a catheter is a scanning fiber endoscope. The images facilitate navigation through linked body lumens and also enable an operator to view a site where a biopsy sample is to be taken with a cannula tool. Exemplary cannula tools include bristles or sharp points that scrub cells from adjacent tissue, a biopsy needle that can be thrust into tissue, a loop that cuts away tissue, a cutting edge that slices tissue from a site, and forceps. The sample can be carried by a bodily or introduced fluid to a proximal end of the catheter through an annular gap between the catheter and the cannula tool, or the cannula tool can retain the sample. |
FILED | Monday, April 02, 2007 |
APPL NO | 11/695287 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/0008 (20130101) A61B 1/00172 (20130101) A61B 10/02 (20130101) Original (OR) Class A61B 10/04 (20130101) A61B 10/06 (20130101) A61B 10/0266 (20130101) A61B 10/0283 (20130101) A61B 2017/320004 (20130101) A61B 2017/320008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840571 | Egorov et al. |
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FUNDED BY |
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APPLICANT(S) | Vladimir Egorov (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey) |
ASSIGNEE(S) | Artann Laboratories Inc. (Trenton, New Jersey) |
INVENTOR(S) | Vladimir Egorov (Princeton, New Jersey); Armen P. Sarvazyan (Lambertville, New Jersey) |
ABSTRACT | Transvaginal probes equipped with tactile sensors are configured for placement into vagina to record tactile response during insertion, acquire static tactile pattern from vaginal wall after the insertion is complete, and acquire dynamic tactile patterns during probe motion as well as recording dynamic tactile response during contraction of vaginal muscle. The acquired and recorded tactile data are transmitted to a data processor for composing tactile profile of vagina and visually presenting thereof on a display. Elasticity profile of vaginal tissue is calculated from the tactile response recorded from different parts of the probe during its insertion, from the static pressure pattern and from the dynamic tactile pattern. Pelvic floor muscle strength is defined as a contact pressure increase detected on fixed probe surface under the muscle contraction. Tactile profile of vagina is determined using the static tactile pattern, the elasticity profile and pelvic floor muscle strength. The data processor provides a comparative analysis of the tactile profile with a variety of vaginal tactile profiles recorded for a given population with known clinical conditions so as to assist in diagnosing a disease. |
FILED | Friday, February 01, 2013 |
APPL NO | 13/756788 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/227 (20130101) Original (OR) Class A61B 5/4337 (20130101) A61B 5/6847 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840628 | Green et al. |
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FUNDED BY |
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APPLICANT(S) | Philip S. Green (Redwood City, California); Joel F. Jensen (Redwood City, California) |
ASSIGNEE(S) | Intuitive Surgical Operations, Inc. (Sunnyvale, California) |
INVENTOR(S) | Philip S. Green (Redwood City, California); Joel F. Jensen (Redwood City, California) |
ABSTRACT | The invention is directed to mainpulator assembly (2) for holding and manipulating a surgical instrument (14) in a telerobotic system. The assembly comprises a base (6) fixable by passive or power driven positioning devices to a surface, such as an operating table, and an instrument holder (4) movably mounted on the base. The instrument holder comprises a chassis (6) and an instrument support (70) movably mounted on the body and having an interface engageable with the surgical instrument to releasably mount the instrument to the instrument holder. A drive assembly (7) is operatively coupled to the instrument holder for providing the instrument with at least two degrees of freedom. The instrument holder is separable from the base and the drive assembly so that the holder can be sterilized. The assembly further includes a force sensing element (52) mounted distal to the holder and the drive assembly for detecting forces exerted on the surgical instrument and providing feedback to the surgeon. The assembly is attached to a remote center positioner (300) for constraining the instrument to rotate a point coincident with the entry incision and an inclinometer (350) for preventing gravitational forces acting on the system's mechanisms from being felt by the surgeon. |
FILED | Wednesday, July 10, 2013 |
APPL NO | 13/938515 |
ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/29 (20130101) A61B 19/22 (20130101) A61B 19/26 (20130101) A61B 19/2203 (20130101) Original (OR) Class A61B 2017/00477 (20130101) A61B 2017/3445 (20130101) A61B 2019/223 (20130101) A61B 2019/265 (20130101) A61B 2019/2211 (20130101) A61B 2019/2234 (20130101) A61B 2019/2242 (20130101) A61B 2019/4868 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 3/04 (20130101) B25J 15/04 (20130101) B25J 18/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840866 | Kung et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Hank F. Kung (Springfield, Pennsylvania); Mei-Ping Kung (Wynnewood, Pennsylvania) |
ABSTRACT | This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits. |
FILED | Monday, January 07, 2013 |
APPL NO | 13/735609 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0455 (20130101) Heterocyclic Compounds C07D 211/94 (20130101) Original (OR) Class C07D 213/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840868 | Thurman et al. |
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FUNDED BY |
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APPLICANT(S) | Joshua M. Thurman (Greenwood Village, Colorado); Natalie Serkova (Denver, Colorado); Conrad Stoldt (Denver, Colorado); Brian Larsen (Denver, Colorado); V. Michael Holers (Denver, Colorado) |
ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Boulder, Colorado) |
INVENTOR(S) | Joshua M. Thurman (Greenwood Village, Colorado); Natalie Serkova (Denver, Colorado); Conrad Stoldt (Denver, Colorado); Brian Larsen (Denver, Colorado); V. Michael Holers (Denver, Colorado) |
ABSTRACT | Methods of non-invasive imaging of complement-mediated inflammation are provided. Compositions including CR-targeted ultrasmall superparamagnetic nanoparticles or aggregates thereof for use with those methods are also provided. |
FILED | Thursday, February 04, 2010 |
APPL NO | 13/148028 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/16 (20130101) A61K 49/1812 (20130101) Original (OR) Class A61K 49/1863 (20130101) A61K 49/1866 (20130101) A61K 49/1875 (20130101) A61K 49/1887 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840889 | Chen |
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FUNDED BY |
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APPLICANT(S) | Lieping Chen (Sparks Glencoe, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Lieping Chen (Sparks Glencoe, Maryland) |
ABSTRACT | Presented herein are therapeutic agents that modulate one or more immune functions and uses of such therapeutic agents in the prevention, treatment and management of diseases. In one aspect, the therapeutic agents modulate one or more signal transduction pathways induced by the binding of B7-H7 to B7-H7CR, or the binding of B7-H2 to either ICOS, CD28, or CTLA-4. In another aspect, the therapeutic agents modulate the binding of B7-H7 to B7-H7CR, or the binding of B7-H2 to either ICOS, CD28, or CTLA-4. The therapeutic agents can be used in the prevention, treatment and/or management of diseases in which it might be useful to modulate one or more immune functions (e.g., cancer, infectious disease, autoimmune disease, and transplantation rejection). In another aspect, presented herein are methods for identifying receptor-ligand interactions. |
FILED | Friday, August 13, 2010 |
APPL NO | 13/390054 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/70521 (20130101) C07K 14/70532 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) Original (OR) Class C07K 2316/95 (20130101) C07K 2316/96 (20130101) C07K 2317/74 (20130101) C07K 2319/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840899 | Ahmed et al. |
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FUNDED BY |
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APPLICANT(S) | Rafi Ahmed (Atlanta, Georgia); Christian P. Larsen (Atlanta, Georgia); Koichi Araki (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Rafi Ahmed (Atlanta, Georgia); Christian P. Larsen (Atlanta, Georgia); Koichi Araki (Atlanta, Georgia) |
ABSTRACT | It is disclosed herein that treatment of a subject with an mTOR inhibitor enhances antigen-specific T cell immune responses. Thus, provided herein is a method of enhancing an antigen-specific T cell response in a subject by administering to the subject a therapeutically effective amount of an mTOR inhibitor. The antigen can be any antigen, such as an antigen from a pathogen or a vaccine, or a tumor antigen. In some embodiments, the method further comprises administering to the subject a vaccine, such as a virus vaccine or a cancer vaccine. The mTOR inhibitor can be administered either before or after vaccination to enhance the quantity and quality of the T cell immune response and immunological memory. In some examples, the mTOR inhibitor is rapamycin or a rapamycin analog. |
FILED | Wednesday, August 05, 2009 |
APPL NO | 13/057057 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 39/12 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/5258 (20130101) A61K 2039/55516 (20130101) A61K 2039/55561 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/10343 (20130101) C12N 2710/24122 (20130101) C12N 2730/10134 (20130101) C12N 2740/13013 (20130101) C12N 2760/10034 (20130101) C12N 2770/10022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840900 | Fischetti et al. |
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FUNDED BY |
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APPLICANT(S) | Vincent A. Fischetti (West Hempstead, New York); Anu Daniel (Lexington, Massachusetts); Chad Euler (New York, New York) |
ASSIGNEE(S) | The Rockefeller University (New York, New York) |
INVENTOR(S) | Vincent A. Fischetti (West Hempstead, New York); Anu Daniel (Lexington, Massachusetts); Chad Euler (New York, New York) |
ABSTRACT | The present disclosure relates to chimeric bacteriophage lysins useful for the identification and/or reduction of staphylococcal populations. For example, a chimeric bacteriophage lysin was engineered and shown to effectively kill all strains of staphylococci tested including antibiotic resistant methicillin-resistant S. aureus (MRSA) and vancomycin-resistant Staphylococcus aureus (VISA). |
FILED | Wednesday, July 01, 2009 |
APPL NO | 13/502912 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Drug, bio-affecting and body treating compositions 424/186.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840903 | Vilalta et al. |
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FUNDED BY |
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APPLICANT(S) | Adrian Vilalta (San Diego, California); Michal Margalith (Solana Beach, California); Lichun Dong (Seattle, Washington); David M. Koelle (Seattle, Washington) |
ASSIGNEE(S) | Vical Incorporated (San Diego, California) |
INVENTOR(S) | Adrian Vilalta (San Diego, California); Michal Margalith (Solana Beach, California); Lichun Dong (Seattle, Washington); David M. Koelle (Seattle, Washington) |
ABSTRACT | This invention relates to therapeutic polynucleotide compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in mammals. The polynucleotide compositions are particularly effective for protecting mammals from herpes simplex virus (HSV), such as HSV gD2, VP11/12, and VP13/14 polypeptides. |
FILED | Thursday, August 09, 2012 |
APPL NO | 13/571247 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) Original (OR) Class A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16622 (20130101) C12N 2710/16634 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840904 | Vilalta et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Washington (Seattle, Washington) |
ASSIGNEE(S) | Vical Incorporated (San Diego, California); The University of Washington (Seattle, Washington) |
INVENTOR(S) | Adrian Vilalta (San Diego, California); Michal Margalith (Solana Beach, California); Lichun Dong (Seattle, Washington); David M. Koelle (Seattle, Washington) |
ABSTRACT | This invention relates to therapeutic polynucleotide compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in mammals. The polynucleotide compositions are particularly effective for protecting mammals from herpes simplex virus (HSV), such as HSV VP11/12 polypeptides. |
FILED | Friday, March 15, 2013 |
APPL NO | 13/843093 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) Original (OR) Class A61K 2039/53 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16622 (20130101) C12N 2710/16634 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840906 | Bubeck-Wardenburg et al. |
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FUNDED BY |
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APPLICANT(S) | Juliane Bubeck-Wardenburg (Frankfort, Illinois); Olaf Schneewind (Chicago, Illinois); Brook Ragle (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Juliane Bubeck-Wardenburg (Frankfort, Illinois); Olaf Schneewind (Chicago, Illinois); Brook Ragle (Chicago, Illinois) |
ABSTRACT | Embodiments of the invention include methods and compositions useful in a vaccination strategy capable of neutralizing HIa to provide immunoprotection against S. aureus pneumonia. In certain aspects the invention includes a HIa with reduced toxicity, represented by a recombinant mutant form of HIa (HlaH35L) in which histidine 35 is converted to leucine, which can be used to abrogate the productive assembly of the toxin and protect a subject from staphylococcal pneumonia. |
FILED | Friday, August 29, 2008 |
APPL NO | 12/675597 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/1271 (20130101) C07K 2316/96 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840908 | Reed et al. |
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FUNDED BY |
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APPLICANT(S) | Steven G. Reed (Bellevue, Washington); Darrick Carter (Seattle, Washington) |
ASSIGNEE(S) | Infectious Disease Research Institute (Seattle, Washington) |
INVENTOR(S) | Steven G. Reed (Bellevue, Washington); Darrick Carter (Seattle, Washington) |
ABSTRACT | Compositions and methods, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response are disclosed based on the discovery of useful immunological adjuvant properties in a synthetic, glucopyranosyl lipid adjuvant (GLA) that is provided in substantially homogeneous form. Chemically defined, synthetic GLA offers a consistent vaccine component from lot to lot without the fluctuations in contaminants or activity that compromise natural-product adjuvants. Also provided are vaccines and pharmaceutical compositions that include GLA and one or more of an antigen, a Toll-like receptor (TLR) agonist, a co-adjuvant and a carrier such as a pharmaceutical carrier. |
FILED | Thursday, August 30, 2012 |
APPL NO | 13/599701 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/35 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/55511 (20130101) A61K 2039/55572 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841068 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | Harold C. Smith (Rochester, New York); Xia Jin (Fairpoint, New York); Andrew Brooks (New York, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Harold C. Smith (Rochester, New York); Xia Jin (Fairpoint, New York); Andrew Brooks (New York, New York) |
ABSTRACT | The present invention provides compositions and methods related to determining the severity of viral infections and identifying antiviral agents. In certain embodiments, the invention comprises determining the expression level of APOBEC-1 related proteins, where the expression level of APOBEC-1 related proteins is an indicator for disease severity and/or effectiveness of a potential antiviral agent. In one embodiment, the present invention provides for a method of screening for an antiviral agent. |
FILED | Monday, February 13, 2006 |
APPL NO | 11/816063 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841077 | Paige et al. |
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FUNDED BY |
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APPLICANT(S) | Lisa A. Paige (Hillsborough, North Carolina); Matthew W. Mitchell (Durham, North Carolina); Anne Evans (Durham, North Carolina); Don Harvan (Durham, North Carolina); Kay A. Lawton (Raleigh, North Carolina); Robert Brown (Needham, Massachusetts); Merit Cudkowicz (Newton, Massachusetts) |
ASSIGNEE(S) | Massachusetts General Hospital (Boston, Massachusetts); Metabolon, Inc. (Durham, North Carolina) |
INVENTOR(S) | Lisa A. Paige (Hillsborough, North Carolina); Matthew W. Mitchell (Durham, North Carolina); Anne Evans (Durham, North Carolina); Don Harvan (Durham, North Carolina); Kay A. Lawton (Raleigh, North Carolina); Robert Brown (Needham, Massachusetts); Merit Cudkowicz (Newton, Massachusetts) |
ABSTRACT | The present invention provides various biomarkers of amyotrophic lateral sclerosis (ALS). The present invention also provides various methods of using the biomarkers, including methods for diagnosis of ALS, methods of determining predisposition to ALS, methods of monitoring progression/regression of ALS, methods of assessing efficacy of compositions for treating ALS, methods of screening compositions for activity in modulating biomarkers of ALS, methods of treating ALS, as well as other methods based on biomarkers of ALS. |
FILED | Tuesday, February 27, 2007 |
APPL NO | 11/711518 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2500/10 (20130101) G01N 2800/28 (20130101) G01N 2800/56 (20130101) G01N 2800/2835 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841083 | Heath et al. |
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FUNDED BY |
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APPLICANT(S) | James R. Heath (South Pasadena, California); Heather Dawn Agnew (Culver City, California); Suresh Mark Pitram (La Jolla, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Indi Molecular, Inc. (Culver City, California) |
INVENTOR(S) | James R. Heath (South Pasadena, California); Heather Dawn Agnew (Culver City, California); Suresh Mark Pitram (La Jolla, California) |
ABSTRACT | Disclosed herein are novel synthetic prostate specific antigen (PSA)-targeted capture agents that specifically bind PSA. In certain embodiments, these PSA capture agents are biligand or triligand capture agents containing two or three target-binding moieties, respectively. |
FILED | Friday, February 03, 2012 |
APPL NO | 13/366196 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841086 | Han et al. |
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FUNDED BY |
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APPLICANT(S) | Immunetics, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Immunetics, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Andrew Han (Cambridge, Massachusetts); Andrew E. Levin (Boston, Massachusetts); Neil X. Krueger (Roslindale, Massachusetts); Victor Kovalenko (Saco, Maine) |
ABSTRACT | The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-β-D-glucan in a sample. |
FILED | Tuesday, May 21, 2013 |
APPL NO | 13/898683 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/25 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841092 | Thorson et al. |
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FUNDED BY |
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APPLICANT(S) | Jon S. Thorson (Middleton, Wisconsin); Changsgeng Zhang (Madison, Wisconsin); Byron R. Griffith (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Jon S. Thorson (Middleton, Wisconsin); Changsgeng Zhang (Madison, Wisconsin); Byron R. Griffith (Madison, Wisconsin) |
ABSTRACT | The present invention relates to methods of use of glycosyltransferases and related compounds. The invention exploits the reversibility of glycosyltransferases to generate new sugars, unnatural biomolecules and numerous one-pot reactions for generation of new biomolecules having varied backbones such as enediynes, vancomycins, bleomycins, anthracyclines, macrolides, pluramycins, aureolic acids, indolocarbazoles, aminglycosides, glycopeptides, polyenes, coumarins, benzoisochromanequinones, calicheamicins, erythromycin, avermectins, ivermectins, angucyclines, cardiac glycosides, steroids or flavinoids. In preferred embodiments, the invention specifically relates to biosynthesis of anticancer (the enediyne calicheamicin, CLM), anthelmintic agents (the macrolides avermectin, ivermectin and erythromycin) and antibiotic (the glycopeptide vancomycin, VCM) natural product-based drugs developed by reversible, bidirectional glycosyltransferase-catalyzed reactions. |
FILED | Thursday, August 30, 2007 |
APPL NO | 11/847731 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) C07H 17/08 (20130101) C07H 19/01 (20130101) Peptides C07K 9/008 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/18 (20130101) C12P 19/44 (20130101) C12P 19/623 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841109 | Holyoak et al. |
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FUNDED BY |
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APPLICANT(S) | Todd Holyoak (Lenexa, Kansas); Jiazhou Qiu (Westborough, Massachusetts); Andrew G. Plaut (Lexington, Massachusetts) |
ASSIGNEE(S) | The University of Kansas (Kansas City, Kansas); Tufts Medical Center, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Todd Holyoak (Lenexa, Kansas); Jiazhou Qiu (Westborough, Massachusetts); Andrew G. Plaut (Lexington, Massachusetts) |
ABSTRACT | Polypeptide agents useful in the treatment of IgA1 deposition diseases and methods of using such polypeptide agents. Methods of screening for inhibitors of IgA1 proteases and agents that inhibit IgA1 proteases are also disclosed. |
FILED | Tuesday, April 20, 2010 |
APPL NO | 13/265479 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 2299/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841116 | Mathies et al. |
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FUNDED BY |
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APPLICANT(S) | Richard A. Mathies (Moraga, California); Robert Blazej (San Francisco, California); Palani Kumaresan (Berkeley, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Richard A. Mathies (Moraga, California); Robert Blazej (San Francisco, California); Palani Kumaresan (Berkeley, California) |
ABSTRACT | Methods and microfluidic circuitry for inline injection of nucleic acids for capillary electrophoresis analysis are provided. According to various embodiments, microfabricated structures including affinity-based capture matrixes inline with separation channels are provided. The affinity-based capture matrixes provide inline sample plug formation and injection into a capillary electrophoresis channel. Also provided are methods and apparatuses for a microbead-based inline injection system for DNA sequencing. |
FILED | Thursday, October 25, 2007 |
APPL NO | 11/978224 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502753 (20130101) B01L 3/502784 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/027 (20130101) B01L 2200/0631 (20130101) B01L 2200/0673 (20130101) B01L 2300/0803 (20130101) B01L 2400/0421 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 27/44743 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841137 | DeLouise et al. |
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FUNDED BY |
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APPLICANT(S) | Lisa DeLouise (Rochester, New York); Lisa Bonanno (Rochester, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Lisa DeLouise (Rochester, New York); Lisa Bonanno (Rochester, New York) |
ABSTRACT | Disclosed is a product that includes an optical sensor; a target-responsive hydrogel matrix on a surface of the optical sensor (where the hydrogel matrix comprises one or more target-specific receptors and one or more target analogs), and one or more high refractive index nanoparticles within the hydrogel matrix, where a detectable change occurs in a refractive index of the hydrogel matrix when contacted with one or more target molecules. Sterile packages and detection devices containing the product, and methods of detecting a target molecule using the product, are also disclosed. |
FILED | Friday, February 25, 2011 |
APPL NO | 13/035887 |
ART UNIT | 1677 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54386 (20130101) G01N 338/54306 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 436/805 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841253 | Murphy et al. |
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FUNDED BY |
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APPLICANT(S) | John R. Murphy (Boston, Massachusetts); Ryan Ratts (Boston, Massachusetts) |
ASSIGNEE(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
INVENTOR(S) | John R. Murphy (Boston, Massachusetts); Ryan Ratts (Boston, Massachusetts) |
ABSTRACT | The invention features methods for identifying compounds that inhibit cell death, and methods for identifying compounds that promote cell death, by blocking or accelerating, respectively, the translocation of the catalytic domain of toxins or transcription factors through the endosomal membrane into the cytosol of a cell. Also featured are methods for inhibiting cell death that include the administration of polypeptides that include a toxin consensus sequence recognized by one or more components of the cytosolic translocation factor complex. |
FILED | Wednesday, August 30, 2006 |
APPL NO | 12/065066 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/12 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841255 | Chilkoti |
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FUNDED BY |
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APPLICANT(S) | Ashutosh Chilkoti (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina) |
ABSTRACT | The present invention provides therapeutic agents and compositions comprising elastic peptides and therapeutic proteins. Such peptides exhibit a flexible, extended conformation. In some embodiments, the therapeutic protein is a GLP-1 receptor agonist (e.g., GLP-1, exendin), insulin, or Factor VII/VIIa, including functional analogs. The present invention further provides encoding polynucleotides, as well as methods of making and using the therapeutic agents. The therapeutic agents have improvements in relation to their use as therapeutics, including, inter alia, one or more of half-life, clearance and/or persistence in the body, solubility, and bioavailability. |
FILED | Friday, August 06, 2010 |
APPL NO | 12/852365 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/2278 (20130101) A61K 38/2278 (20130101) A61K 38/4846 (20130101) A61K 38/4846 (20130101) A61K 45/06 (20130101) A61K 47/48246 (20130101) Original (OR) Class A61K 47/48292 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/52 (20130101) C07K 14/62 (20130101) C07K 14/71 (20130101) C07K 14/78 (20130101) C07K 14/605 (20130101) C07K 14/745 (20130101) C07K 2319/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841257 | McMurray et al. |
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FUNDED BY |
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APPLICANT(S) | John S. McMurray (Houston, Texas); Pijus K. Mandal (Houston, Texas); Warren S. Liao (Houston, Texas); Fredika Robertson (Houston, Texas); Xiaomin Chen (Houston, Texas); Ramesh Rajaopal (Sugarland, Texas); Zhiyong Ren (Houston, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | John S. McMurray (Houston, Texas); Pijus K. Mandal (Houston, Texas); Warren S. Liao (Houston, Texas); Fredika Robertson (Houston, Texas); Xiaomin Chen (Houston, Texas); Ramesh Rajaopal (Sugarland, Texas); Zhiyong Ren (Houston, Texas) |
ABSTRACT | Compounds which inhibit the activity of signal transducer and activator of transcription 3 (STAT3) are provided together with methods of making and using the same. The compounds are designed to bind to the SH2 domain of STAT3, preventing STAT3 from binding to receptors for interleukin-6 family cytokines, growth factors such as the platelet-derived growth factor, the epidermal growth factor, vascular endothelial growth factor, and other signaling molecules such as leptin. Blocking these interactions prevents STAT3 from being phosphorylated on Tyr705, which is required for the dimerization of STAT3, translocation to the nucleus, binding to STAT3 response elements on promotors, and transcription of genes. In addition to these activities, binding to the SH2 domain of STAT3 breaks up pre-formed dimmers, thereby preventing the transcriptional activity of the inhibitor. |
FILED | Friday, April 09, 2010 |
APPL NO | 13/263815 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/66 (20130101) A61K 31/437 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/12 (20130101) C07F 9/5532 (20130101) C07F 9/5721 (20130101) Original (OR) Class C07F 9/5728 (20130101) C07F 9/6539 (20130101) C07F 9/6561 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841259 | Feener et al. |
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FUNDED BY |
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APPLICANT(S) | Edward P. Feener (North Reading, Massachusetts); Lloyd P. Aiello (Belmont, Massachusetts) |
ASSIGNEE(S) | Joslin Diabetes Center (Boston, Massachusetts) |
INVENTOR(S) | Edward P. Feener (North Reading, Massachusetts); Lloyd P. Aiello (Belmont, Massachusetts) |
ABSTRACT | The present invention provides methods and composition for the treatment and diagnosis of disorders associated with excessive vascular permeability and edema. |
FILED | Thursday, February 16, 2006 |
APPL NO | 11/884503 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/527 (20130101) C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841266 | Izraeli et al. |
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FUNDED BY |
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APPLICANT(S) | Shai Izraeli (ModiIn, Israel); Ilan R. Kirsch (Seattle, Washington); Ayelet Erez (Moshav Bnei Tzion, Israel); Stefano Campaner (Milan, Italy) |
ASSIGNEE(S) | Tel Hashomer Medical Research Infrastructure and Services Ltd. (Ramat-Gan, Israel); The United States of America as represented by the Secretary of the Department of Health and Human Services National Institutes of Health Office of Technology Transfer (Washington, District of Columbia) |
INVENTOR(S) | Shai Izraeli (ModiIn, Israel); Ilan R. Kirsch (Seattle, Washington); Ayelet Erez (Moshav Bnei Tzion, Israel); Stefano Campaner (Milan, Italy) |
ABSTRACT | A method of treating a disease associated with a cell population which proliferates abnormally in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of at least one modulator capable of modulating in the cell population a level and/or activity of a polypeptide having an amino acid sequence at least 60 percent similar to SEQ ID NO: 5, as determined using the Standard protein-protein BLAST [blastp] software of the NCBI. |
FILED | Thursday, November 16, 2006 |
APPL NO | 12/085023 |
ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841273 | Adam et al. |
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FUNDED BY |
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APPLICANT(S) | Liana Adam (Pearland, Texas); Colin P. Dinney (Houston, Texas); David J. McConkey (Bellaire, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Liana Adam (Pearland, Texas); Colin P. Dinney (Houston, Texas); David J. McConkey (Bellaire, Texas) |
ABSTRACT | In some embodiments, the present invention provides methods for enhancing the sensitivity of cancer cells to anti-EGFR treatment, wherein the method comprises the introduction of a miR-200 miRNA to the cancer cells. In other embodiments, the present invention provides methods for treating cancer by exposing the cancer cells to an anti-EGFR composition after the above-mentioned enhancement step. In other embodiments, the present invention provides methods for assessing and enhancing the sensitivity of cancer cells to anti-EGFR treatment. In various other embodiments, the present invention provides compositions and expression vectors for practicing the afore-mentioned methods. |
FILED | Thursday, October 28, 2010 |
APPL NO | 13/504696 |
ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/141 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841276 | Arbiser |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia); The United States of America Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Jack L. Arbiser (Atlanta, Georgia) |
ABSTRACT | Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are fulvene and/or fulvalene analogs. The compounds and compositions can be used to treat and/or prevent a wide variety of cancers, including drug resistant cancers, as well as numerous inflammatory, degenerative and vascular diseases, including various ocular diseases. Representative fulvene and/or fulvalene analogs include fulvene and fulvalene analogs of various dyes, hormones, sugars, peptides, oligonucleotides, amino acids, nucleotides, nucleosides, and polyols. The compounds are believed to function, at least, by inhibiting Nox or ROS. In some embodiments, the Nox is one that is selectively expressed in cancer cells over normal cells, or one that is expressed in higher amounts in cancer cells over normal cells. Thus, the compounds are novel therapeutic agents for a variety of cancers and other diseases. |
FILED | Tuesday, August 20, 2013 |
APPL NO | 13/970639 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/015 (20130101) A61K 31/045 (20130101) A61K 31/167 (20130101) A61K 31/341 (20130101) A61K 31/357 (20130101) A61K 31/403 (20130101) A61K 31/444 (20130101) A61K 31/573 (20130101) A61K 31/4164 (20130101) A61K 31/5375 (20130101) Acyclic or Carbocyclic Compounds C07C 13/28 (20130101) C07C 13/40 (20130101) C07C 13/58 (20130101) C07C 13/66 (20130101) C07C 13/465 (20130101) C07C 25/18 (20130101) C07C 35/32 (20130101) C07C 39/23 (20130101) C07C 43/23 (20130101) C07C 43/215 (20130101) C07C 69/608 (20130101) C07C 211/50 (20130101) C07C 215/46 (20130101) C07C 233/44 (20130101) C07C 237/26 (20130101) C07C 251/28 (20130101) C07C 275/64 (20130101) C07C 2101/10 (20130101) C07C 2102/08 (20130101) C07C 2102/42 (20130101) C07C 2103/24 (20130101) C07C 2103/40 (20130101) C07C 2103/46 (20130101) Heterocyclic Compounds C07D 209/14 (20130101) Original (OR) Class C07D 209/82 (20130101) C07D 209/86 (20130101) C07D 213/53 (20130101) C07D 233/58 (20130101) C07D 233/68 (20130101) C07D 261/08 (20130101) C07D 277/40 (20130101) C07D 295/03 (20130101) C07D 295/135 (20130101) C07D 307/58 (20130101) C07D 309/38 (20130101) C07D 311/58 (20130101) C07D 311/60 (20130101) C07D 311/82 (20130101) C07D 407/04 (20130101) C07D 471/10 (20130101) C07D 473/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841285 | Romo et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel Romo (College Station, Texas); Jun Liu (Clarksville, Maryland); Nam Song Choi (Cheonan, South Korea); Zonggao Shi (Columbia, Maryland); Woon-Kai Low (Baltimore, Maryland); Yongjun Dang (Baltimore, Maryland); Tilman Schneider-Poetsch (Erftstadt, Germany) |
ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); The John Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Daniel Romo (College Station, Texas); Jun Liu (Clarksville, Maryland); Nam Song Choi (Cheonan, South Korea); Zonggao Shi (Columbia, Maryland); Woon-Kai Low (Baltimore, Maryland); Yongjun Dang (Baltimore, Maryland); Tilman Schneider-Poetsch (Erftstadt, Germany) |
ABSTRACT | Provided herein include compositions, all related stereoisomers as well as pharmaceutically acceptable salts provided as simplified analogs of pateamine A, in which the analogs generally are devoid of the C3-amino and C5-methyl groups, also referred to as desmethyl, desamino-pateamine A. Suitable analogs provide anticancer and antiproliferative effects in vivo and in vitro by a novel drugs mechanism of action described herein for pateamine A, including inhibition of eIF4A-dependent translation initiation. As with pateamine A, as described herein, suitable analogs cause cell cycle arrest or induce apoptosis in transformed cells. However, toxicity of such compounds to slow growing normal cells is low. In addition, such analogs, like pateamine A, target translation initiation factors and are useful as anticancer and antiproliferative agents in subjects in need thereof. Moreover, the analogs, like pateamine A, are valuable molecular probes for evaluation of eukaryotic translation initiation and as lead compounds for development of improved anticancer agents. |
FILED | Friday, June 11, 2010 |
APPL NO | 12/813858 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841305 | Thomas et al. |
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FUNDED BY |
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APPLICANT(S) | Craig J. Thomas (Gaithersburg, Maryland); Douglas S. Auld (Potomac, Maryland); James Inglese (Bethesda, Maryland); Amanda P. Skoumbourdis (Langhorne, Pennsylvania); Jian-Kang Jiang (Columbia, Maryland); Matthew B. Boxer (Point of Rocks, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
INVENTOR(S) | Craig J. Thomas (Gaithersburg, Maryland); Douglas S. Auld (Potomac, Maryland); James Inglese (Bethesda, Maryland); Amanda P. Skoumbourdis (Langhorne, Pennsylvania); Jian-Kang Jiang (Columbia, Maryland); Matthew B. Boxer (Point of Rocks, Maryland) |
ABSTRACT | Disclosed are pyruvate kinase M2 activators, which are bis sulfonamide piperazinyl and piperidinyl compounds of Formula (I), 2,4-disubstituted 4H-thieno[3,2-c]pyrrole-2-(substituted benzyl)pyridazin-3(2H)-ones of Formula (II) and 6-(3,4-dimethylphenylaminosulfonyl)-3,4-dihydro-1H-quinolin-2-one of formula (III), wherein L, R1, R2, R11 to R16, R21 and R22 are as defined herein, that are useful in treating a number of diseases that are treatable by the activation of PKM2, for example, cancer and anemia. |
FILED | Friday, October 09, 2009 |
APPL NO | 13/123297 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Drug, bio-affecting and body treating compositions 514/253.40 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841317 | Zughaier et al. |
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FUNDED BY |
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APPLICANT(S) | Susu Zughaier (Atlanta, Georgia); Ritu Aneja (Lilburn, Georgia); David S. Stephens (Stone Mountain, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia State University Research Foundation (Atlanta, Georgia) |
INVENTOR(S) | Susu Zughaier (Atlanta, Georgia); Ritu Aneja (Lilburn, Georgia); David S. Stephens (Stone Mountain, Georgia) |
ABSTRACT | The invention relates to the innate immune pathway and anti-inflammatory molecules with therapeutic properties. In some embodiments, the invention relates to compounds and pharmaceutical compositions and methods of using the compounds and compositions to treat inflammatory diseases including inflammation associated with auto-immune diseases. |
FILED | Wednesday, August 24, 2011 |
APPL NO | 13/216458 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4355 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841329 | Shi et al. |
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FUNDED BY |
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APPLICANT(S) | Fu-Dong Shi (Scottsdale, Arizona); Ronald J. Lukas (Phoenix, Arizona); Timothy Vollmer (Parker, Colorado) |
ASSIGNEE(S) | Dignity Health (Phoenix, Arizona) |
INVENTOR(S) | Fu-Dong Shi (Scottsdale, Arizona); Ronald J. Lukas (Phoenix, Arizona); Timothy Vollmer (Parker, Colorado) |
ABSTRACT | The present invention relates to methods of treating and/or ameliorating the severity of inflammation and autoimmunity in the central nervous system (CNS). In one embodiment, the present invention provides a method of treating multiple sclerosis by administering a therapeutically effective dosage of nicotine, or a pharmaceutical equivalent, analog, derivative, or salt thereof. |
FILED | Friday, September 11, 2009 |
APPL NO | 13/063713 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) Original (OR) Class A61K 31/70 (20130101) A61K 31/465 (20130101) A61K 31/685 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841408 | Messersmith et al. |
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FUNDED BY |
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APPLICANT(S) | Phillip B Messersmith (Clarendon Hills, Illinois); Bi-Huang Hu (Chicago, Illinois); Jing Su (Chicago, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Phillip B Messersmith (Clarendon Hills, Illinois); Bi-Huang Hu (Chicago, Illinois); Jing Su (Chicago, Illinois) |
ABSTRACT | Biocompatible macromonomers, hydrogels, methods of synthesis and methods of use thereof are provided. The biocompatible hydrogels of the present invention are prepared using native chemical ligation (NCL), in which a thioester readily reacts with a N-terminal thiol (cysteine) through transesterification and rearrangement to form an amide bond through a five-member ring intermediate. |
FILED | Monday, April 21, 2008 |
APPL NO | 12/106429 |
ART UNIT | 1675 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/02 (20130101) C08G 69/04 (20130101) C08G 69/08 (20130101) C08G 69/40 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841416 | Ledbetter et al. |
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FUNDED BY |
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APPLICANT(S) | Jeffrey A. Ledbetter (Seattle, Washington); Martha Hayden-Ledbetter (Seattle, Washington); Keith Elkon (Seattle, Washington); Xizhang Sun (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Jeffrey A. Ledbetter (Seattle, Washington); Martha Hayden-Ledbetter (Seattle, Washington); Keith Elkon (Seattle, Washington); Xizhang Sun (Seattle, Washington) |
ABSTRACT | Hybrid nuclease molecules and methods for treating an immune-related disease or disorder in a mammal, and a pharmaceutical composition for treating an immune-related disease in a mammal. |
FILED | Wednesday, August 03, 2011 |
APPL NO | 13/197731 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/96 (20130101) C12N 11/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841422 | Qiu et al. |
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FUNDED BY |
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APPLICANT(S) | Yun Qiu (Ellicott City, Maryland); Zhiyong Guo (Timonium, Maryland); Xi Yang (Baltimore, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | Yun Qiu (Ellicott City, Maryland); Zhiyong Guo (Timonium, Maryland); Xi Yang (Baltimore, Maryland) |
ABSTRACT | The present invention relates to novel androgen receptor splice variants (AR3, AR4, AR4b, AR5 and AR8) and variants and fragments thereof which have a role in the progression of androgen independent prostate cancer. The invention further relates to compositions and methods which can be used to identify and treat prostate cancer based on these novel androgen receptor splice variants, as well as methods for screening agents which modulate the activity and/or expression of the androgen receptor splice variants. Vectors, host cells and recombinant methods for producing the same and transgenic animals are also provided. |
FILED | Thursday, February 23, 2012 |
APPL NO | 13/403029 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/721 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841423 | Anderson et al. |
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FUNDED BY |
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APPLICANT(S) | Mark E. Anderson (Iowa City, Iowa); Peter J. Mohler (Iowa City, Iowa); Douglas R. Spitz, Jr. (Iowa City, Iowa); Jeffrey Robert Erickson (Davis, California) |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
INVENTOR(S) | Mark E. Anderson (Iowa City, Iowa); Peter J. Mohler (Iowa City, Iowa); Douglas R. Spitz, Jr. (Iowa City, Iowa); Jeffrey Robert Erickson (Davis, California) |
ABSTRACT | Calcium/calmodulin dependent protein kinase II (CaMKII) has been found to be directly oxidized, and direct oxidation of CaMKII was observed to result in calcium independent activation of CaMKII. Antibodies that bind specifically to oxidized forms of CaMKII (oxCaMKII) were generated and were utilized to detect oxCaMKII in blood from: (1) mice with cancer; (2) mice with a knock out of the gene encoding methionine sulfoxide reductase; (3) mice injected with angiotensin II; (4) mice injected with bacterial endotoxin; (5) mice fed a pro-oxidant (ketogenic) diet; and (6) mice with cancer that had been treated with experimental therapy. |
FILED | Monday, April 27, 2009 |
APPL NO | 12/430644 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/40 (20130101) Original (OR) Class C07K 16/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2800/26 (20130101) G01N 2800/32 (20130101) G01N 2800/2821 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841428 | Seeman et al. |
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FUNDED BY |
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APPLICANT(S) | Nadrian C. Seeman (New York, New York); Shiping Liao (New York, New York); James Canary (New York, New York); Hong Zhong (Brooklyn, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Nadrian C. Seeman (New York, New York); Shiping Liao (New York, New York); James Canary (New York, New York); Hong Zhong (Brooklyn, New York) |
ABSTRACT | A polynucleic acid nanomechanical device with a linear array of alternating PX-JX2 devices and nucleic acid multi-crossover motifs that facilitate the assembly of a nucleic acid strand and functions as an artificial ribosome by translating a nucleic acid signal into an unrelated nucleic acid sequence. |
FILED | Friday, July 29, 2005 |
APPL NO | 11/192401 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1031 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class C12P 21/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841436 | Gorodeski et al. |
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FUNDED BY |
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APPLICANT(S) | George Gorodeski (Beachwood, Ohio); Judith Potashkin (Gurnee, Illinois); Bentley Cheatham (Durham, North Carolina) |
ASSIGNEE(S) | University Hospitals Cleveland Medical Center (Cleveland, Ohio); Rosalind Franklin University of Medicine and Science, an Illinois Corporation (North Chicago, Illinois) |
INVENTOR(S) | George Gorodeski (Beachwood, Ohio); Judith Potashkin (Gurnee, Illinois); Bentley Cheatham (Durham, North Carolina) |
ABSTRACT | A relationship between cancer and ribonucleic acid (RNA) regulation is described by determining intracellular levels of niRN A regulators. Generally, mRNA levels are decreased in cancer cells that may be a reflection of either reduced mRNA expression and/or increased mRNA degradation. miRNAs are identified that hybridize to an mRNA that are suspected to mediate intracellular mRNA steady state levels. Alternatively, ribonucleic acid binding protein (RBP) levels may also mediate intracellular mRNA steady state levels. In particular, this invention demonstrates an effective clinical management strategy for uterine cell cancers may be implemented by taking advantage of an exemplary relationship between P2X7 mRNA and miRNAs including, but not limited to, miR-186 and/or miR-150. |
FILED | Thursday, March 13, 2008 |
APPL NO | 12/450124 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/11 (20130101) C12N 2330/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6886 (20130101) C12Q 2522/10 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/178 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841437 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Chang-Zheng Chen (Stanford, California); Robin Trujillo (Mountain View, California); Sibiao Yue (Palo Alto, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Chang-Zheng Chen (Stanford, California); Robin Trujillo (Mountain View, California); Sibiao Yue (Palo Alto, California) |
ABSTRACT | Modulation of mRNA activity is achieved with precursor miRNAs (ta-RNAs). ta-RNAs, primarily pre-miRNAs and pri-miRNAs, including truncated and mutated ta-RNAs, are employed for modulation of mRNA expression where it is found that pri- and pre-miRNA have activity independently of the presence of functional mature miRNAs. Modification of at least one of the stem and loop of the ta-RNAs to enhance binding of the ta-RNA to the target mRNA is employed. The modification may be enhanced complementarity between the ta-RNA and the target mRNA and/or improved thermodynamic efficiency in binding of the ta-RNA to the target. |
FILED | Friday, May 28, 2010 |
APPL NO | 12/802084 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 2310/141 (20130101) C12N 2501/42 (20130101) C12N 2501/515 (20130101) C12N 2506/11 (20130101) C12N 2510/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6811 (20130101) C12Q 2525/207 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841438 | Tenenbaum et al. |
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FUNDED BY |
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APPLICANT(S) | Scott A. Tenenbaum (Selkirk, New York); Francis J. Doyle, II (Albany, New York); Ajish George (Timonium, Maryland); Christopher Zaleski (Huntington, New York) |
ASSIGNEE(S) | The Research Foundation of the University of New York (Albany, New York) |
INVENTOR(S) | Scott A. Tenenbaum (Selkirk, New York); Francis J. Doyle, II (Albany, New York); Ajish George (Timonium, Maryland); Christopher Zaleski (Huntington, New York) |
ABSTRACT | Disclosed are RNA constructs which function to activate or inactivate a biological process, e.g., may be designed for attachment to a polypeptide coding region. Such RNA constructs modulate translation of a polypeptide from the coding region in response to the presence of a target polynucleotide in an expression environment. Such RNA constructs include a weakened stem-loop structure which, when bound to the target polynucleotide, assumes stem-loop secondary structure and associates with an RNA binding protein. Association with the RNA binding protein modulates translation of the polypeptide coding region. Such RNA constructs also have three-way junction joining regions 3′ and 5′ of the stem-loop structure. |
FILED | Friday, May 21, 2010 |
APPL NO | 13/321816 |
ART UNIT | 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Organic compounds 536/24.500 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841460 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | State of Oregon, acting by and through the State Board of Higher Education on behalf of University of Oregon (Eugene, Oregon) |
ASSIGNEE(S) | State of Oregon Acting by and Through the State Board of Higher Education on Behalf of the University of Oregon (Igene, Oregon) |
INVENTOR(S) | Darren W. Johnson (Eugene, Oregon); Calden Carroll (Eugene, Oregon); Michael M. Haley (Eugene, Oregon); Jeff Engle (Eugene, Oregon) |
ABSTRACT | A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl. |
FILED | Friday, December 14, 2012 |
APPL NO | 13/715979 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/337 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841602 | Schulte et al. |
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FUNDED BY |
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APPLICANT(S) | Reinhard W. Schulte (Grand Terrace, California); R. Ford Hurley (Loma Linda, California) |
ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
INVENTOR(S) | Reinhard W. Schulte (Grand Terrace, California); R. Ford Hurley (Loma Linda, California) |
ABSTRACT | Disclosed are systems, devices and methodologies related to calibration of an ion based imaging apparatus such as a proton computed tomography scanner. In some implementations, energy degrader plates having known water-equivalent thickness (WET) values can be introduced to an ion beam to introduce different energy degradation settings. Energy detector responses to individual ions subject to such energy degradation settings can be obtained. Such responses can be normalized and correlated to water-equivalent path lengths (WEPL) of the ions based on the known WET values. Such calibration utilizing degrader plates can be performed relatively quickly and can yield accurate WEPL values that facilitate estimation of, for example, a CT image based on relative stopping power of an object. |
FILED | Tuesday, March 06, 2012 |
APPL NO | 13/413499 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/583 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843188 | Kilgore et al. |
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FUNDED BY |
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APPLICANT(S) | Kevin Kilgore (Avon Lake, Ohio); Douglas Michael Ackermann, Jr. (Palo Alto, California); Niloy Bhadra (Cleveland Heights, Ohio); Narendra Bhadra (Chesterland, Ohio); Joe Payer (Brecksville, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
INVENTOR(S) | Kevin Kilgore (Avon Lake, Ohio); Douglas Michael Ackermann, Jr. (Palo Alto, California); Niloy Bhadra (Cleveland Heights, Ohio); Narendra Bhadra (Chesterland, Ohio); Joe Payer (Brecksville, Ohio) |
ABSTRACT | Example adjustable electrodes are described. One example adjustable electrode includes two or more contacts configured to selectively deliver high frequency alternating current (HFAC) to a nerve in an amount sufficient to produce an HFAC nerve conduction block in the nerve. The example adjustable electrode also includes a logic configured to selectively control which of the two or more contacts deliver HFAC to the nerve to control whether the nerve electrode is in a first (e.g., onset response mitigating) configuration or in a second (e.g., HFAC nerve conduction block maintenance) configuration. The electrode may be used in applications including, but not limited to, nerve block applications, and nerve stimulation applications. The electrode may be adjusted by changing attributes including, but not limited to, the number, length, orientation, distance between, surface area, and distance from a nerve of contacts to be used to deliver the HFAC. |
FILED | Thursday, November 18, 2010 |
APPL NO | 12/948848 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) Original (OR) Class A61N 1/36185 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843201 | Heldman et al. |
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FUNDED BY |
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APPLICANT(S) | Dustin A Heldman (Shaker Heights, Ohio); Joseph P Giuffrida (Hinckley, Ohio) |
ASSIGNEE(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
INVENTOR(S) | Dustin A Heldman (Shaker Heights, Ohio); Joseph P Giuffrida (Hinckley, Ohio) |
ABSTRACT | The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders. |
FILED | Thursday, October 03, 2013 |
APPL NO | 14/045336 |
ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843320 | Shaughnessy et al. |
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FUNDED BY |
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APPLICANT(S) | John D. Shaughnessy (Little Rock, Arkansas); Fenghuang Zhan (Little Rock, Arkansas); Bart Barlogie (Little Rock, Arkansas) |
ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
INVENTOR(S) | John D. Shaughnessy (Little Rock, Arkansas); Fenghuang Zhan (Little Rock, Arkansas); Bart Barlogie (Little Rock, Arkansas) |
ABSTRACT | Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to over-expression of genes such as ASPM, OPN3 and CKS1B which are located in chromosome 1q. Given the frequent amplification of 1q in many cancers, it is possible that these genes can be used as powerful prognostic markers and therapeutic targets for multiple myeloma and other cancer. |
FILED | Friday, May 20, 2005 |
APPL NO | 11/133937 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 08839618 | Blottman, III et al. |
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FUNDED BY |
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APPLICANT(S) | John B. Blottman, III (North Andover, Massachusetts); Barbar J. Akle (Jounieh, Lebanon) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | John B. Blottman, III (North Andover, Massachusetts); Barbar J. Akle (Jounieh, Lebanon) |
ABSTRACT | A buoyancy engine is provided for use in a saltwater environment. The engine includes a gas filled housing and a buoyancy chamber in the housing. An elastomeric membrane is positioned between the buoyancy chamber interior and the housing interior. A semi-permeable membrane is provided between the buoyancy chamber interior and the saltwater environment. Two electrodes can be positioned with both electrodes in the buoyancy chamber or with one electrode being positioned in the buoyancy chamber and the other being positioned in the saltwater environment. A controller is joined to at least one of the electrodes for controlling an electrical potential between the two electrodes. A power source provides power to the controller. |
FILED | Friday, September 21, 2012 |
APPL NO | 13/623930 |
ART UNIT | 3748 — SELECT * FROM codes_techcenter; |
CURRENT CPC | Power plants 060/496 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840304 | Perez Zarate et al. |
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FUNDED BY |
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APPLICANT(S) | Victor Manuel Perez Zarate (Halfmoon, New York); Michael Anthony Rumsey (Niskayuna, New York); Andrea Marie Schmitz (Niskayuna, New York); Jeffrey Wayne Eberhard (Albany, New York); Scott Dana Tilton (Alexandria, Virginia); Tobias George Harvey (Lorton, Virginia) |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Victor Manuel Perez Zarate (Halfmoon, New York); Michael Anthony Rumsey (Niskayuna, New York); Andrea Marie Schmitz (Niskayuna, New York); Jeffrey Wayne Eberhard (Albany, New York); Scott Dana Tilton (Alexandria, Virginia); Tobias George Harvey (Lorton, Virginia) |
ABSTRACT | A flexible, lightweight, easily maneuverable positioner for an imaging system. The positioning system in one example has a cart section with a base frame coupled to one or more wheels. There is a mast extending from the cart section and a linkage assembly coupled to a second end of the mast, wherein the mast is configured to swing about a vertical plane. There is a positioning arm coupled to the linkage assembly, wherein the positioning arm is configured to swing about at least one of a horizontal plane and the vertical plane. An imaging bracket is used to couple to the positioning arm and configured to receive an imaging unit. In one example, the positioner is coupled together by fasteners, wherein the positioner can be assembled and dis-assembled via the fasteners without tools. |
FILED | Wednesday, December 29, 2010 |
APPL NO | 12/980392 |
ART UNIT | 2882 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/447 (20130101) A61B 6/4405 (20130101) A61B 6/4458 (20130101) Original (OR) Class A61B 2019/265 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840355 | Kulesha |
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FUNDED BY |
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APPLICANT(S) | Richard L. Kulesha (Bear, Delaware) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Richard L. Kulesha (Bear, Delaware) |
ABSTRACT | A method and apparatus for handling cargo. A cargo handling system may be positioned relative to the cargo. The cargo handling system may comprise a frame structure and an engagement system. The frame structure may be configured to change in a number of dimensions to encompass the cargo. The engagement system may be configured to engage the cargo. The number of dimensions of the frame structure may be adjusted to encompass the cargo. The cargo may be engaged with the engagement system. |
FILED | Monday, August 16, 2010 |
APPL NO | 12/856726 |
ART UNIT | 3652 — Material and Article Handling |
CURRENT CPC | Material or article handling 414/626 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840359 | Vick et al. |
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FUNDED BY |
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APPLICANT(S) | Michael J. Vick (Vienna, Virginia); Keith R. Pullen (London, United Kingdom) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael J. Vick (Vienna, Virginia); Keith R. Pullen (London, United Kingdom) |
ABSTRACT | A rotor assembly, including at least one driven member, e.g., a compressor rotor, and at least one driving member, e.g., a turbine. At least one rotating thermal insulator rigidly attached to either the driven member or the driving member. A coupling feature that includes mating geometric surfaces on the driven member and the driving member, wherein the geometric surfaces are configured to allow radial sliding, relative centering, torque transmission, and axial constraint between the driven member and the driving member. |
FILED | Thursday, October 13, 2011 |
APPL NO | 13/272941 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive-displacement Pumps F04D 25/04 (20130101) F04D 29/054 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840681 | Martin et al. |
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FUNDED BY |
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APPLICANT(S) | Jay Martin (Oklahoma City, Oklahoma); Paul J. Biermann (Columbia, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Jay Martin (Oklahoma City, Oklahoma); Paul J. Biermann (Columbia, Maryland) |
ABSTRACT | A prosthetic interface includes an orientation assembly, a mounting plate and a load bearing assembly. The orientation assembly includes an anterior frame portion and a posterior frame portion. The anterior frame portion extends over an anterior portion of a torso of a wearer of the prosthetic interface. The posterior frame portion extends over a posterior portion of the torso. The mounting plate is disposed at an intersection of the posterior frame portion and the anterior frame portion. The mounting plate forms a structure to which a prosthetic limb is attachable. The load bearing assembly includes breathable fabric forming a load distribution matrix to distribute a load on the mounting plate over portions of the torso with which the fabric is in contact. |
FILED | Thursday, June 14, 2012 |
APPL NO | 13/523481 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Original (OR) Class A61F 2/78 (20130101) A61F 2/581 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840912 | Melander et al. |
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FUNDED BY |
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APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Christian Melander (Raleigh, North Carolina); Zhaoming Su (Raleigh, North Carolina); Lingling Peng (San Diego, California) |
ABSTRACT | Disclosure is provided for 1,4,5-substituted amino imidazole compounds useful to control microbial growth, compositions including these compounds, devices including these compounds, and methods of using the same. |
FILED | Wednesday, January 09, 2013 |
APPL NO | 13/737161 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/08 (20130101) Original (OR) Class A01N 25/10 (20130101) A01N 25/34 (20130101) A01N 43/50 (20130101) A01N 43/50 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/4168 (20130101) A61K 31/4168 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 233/88 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841068 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | Harold C. Smith (Rochester, New York); Xia Jin (Fairpoint, New York); Andrew Brooks (New York, New York) |
ASSIGNEE(S) | University of Rochester (Rochester, New York) |
INVENTOR(S) | Harold C. Smith (Rochester, New York); Xia Jin (Fairpoint, New York); Andrew Brooks (New York, New York) |
ABSTRACT | The present invention provides compositions and methods related to determining the severity of viral infections and identifying antiviral agents. In certain embodiments, the invention comprises determining the expression level of APOBEC-1 related proteins, where the expression level of APOBEC-1 related proteins is an indicator for disease severity and/or effectiveness of a potential antiviral agent. In one embodiment, the present invention provides for a method of screening for an antiviral agent. |
FILED | Monday, February 13, 2006 |
APPL NO | 11/816063 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841170 | Fadeyev et al. |
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FUNDED BY |
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APPLICANT(S) | Vitaliy Fadeyev (Santa Cruz, California); Hartmut F. W. Sadrozinski (Palo Alto, California); Marc Christophersen (Berwyn Heights, Maryland); Bernard F. Phlips (Great Falls, Virginia) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Naval Research Laboratory (Washington, District of Columbia) |
INVENTOR(S) | Vitaliy Fadeyev (Santa Cruz, California); Hartmut F. W. Sadrozinski (Palo Alto, California); Marc Christophersen (Berwyn Heights, Maryland); Bernard F. Phlips (Great Falls, Virginia) |
ABSTRACT | A method of singulating semiconductor devices in the close proximity to active structures by controlling interface charge of semiconductor device sidewalls is provided that includes forming a scribe on a surface of a semiconductor devices, where the scribe is within 5 degrees of a crystal lattice direction of the semiconductor device, cleaving the semiconductor device along the scribe, where the devices are separated, using a coating process to coat the sidewalls of the cleaved semiconductor device with a passivation material, where the passivation material is disposed to provide a fixed charge density at a semiconductor interface of the sidewalls, and where the fixed charge density interacts with charge carriers in the bulk of the material. |
FILED | Friday, October 21, 2011 |
APPL NO | 13/879971 |
ART UNIT | 2891 — Semiconductors/Memory |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0042 (20130101) B23K 26/0057 (20130101) B23K 26/0081 (20130101) B23K 26/0087 (20130101) B23K 26/367 (20130101) B23K 26/4075 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) Original (OR) Class H01L 31/1804 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841405 | Davis |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Matthew C. Davis (Ridgecrest, California) |
ABSTRACT | A process, thermoset resin, and thermoplastic structures from renewable chemical feedstocks derived from the essential oils from herbs and other plants. The processes for making diphenol products including extracting isomers of 4-methoxyphenylpropene from plant sources, transforming isomers by olefin cross or self-cross olefin metathesis and at least one catalyst to produce dimeric structures having two equivalents of protected phenolic groups, and deprotecting methyl ethers to yield diphenolic products. |
FILED | Thursday, May 02, 2013 |
APPL NO | 13/875459 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 37/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/685 (20130101) C08G 64/1608 (20130101) C08G 65/4018 (20130101) C08G 71/04 (20130101) C08G 73/10 (20130101) C08G 75/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841428 | Seeman et al. |
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FUNDED BY |
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APPLICANT(S) | Nadrian C. Seeman (New York, New York); Shiping Liao (New York, New York); James Canary (New York, New York); Hong Zhong (Brooklyn, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Nadrian C. Seeman (New York, New York); Shiping Liao (New York, New York); James Canary (New York, New York); Hong Zhong (Brooklyn, New York) |
ABSTRACT | A polynucleic acid nanomechanical device with a linear array of alternating PX-JX2 devices and nucleic acid multi-crossover motifs that facilitate the assembly of a nucleic acid strand and functions as an artificial ribosome by translating a nucleic acid signal into an unrelated nucleic acid sequence. |
FILED | Friday, July 29, 2005 |
APPL NO | 11/192401 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1031 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class C12P 21/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841451 | Newkome et al. |
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FUNDED BY |
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APPLICANT(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Chagrin Falls, Ohio) |
ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
INVENTOR(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Chagrin Falls, Ohio) |
ABSTRACT | The invention relates to the formation of synthesized fractal constructs and the methods of chemical self-assembly for the preparation of a non-dendritic, nano-scale, fractal constructs or molecules. More particularly, the invention relates to fractal constructs formed by molecular self-assembly, to create synthetic, nanometer-scale fractal shapes. In an embodiment, a nanoscale Sierpinski hexagonal gasket is formed. This non-dendritic, perfectly self-similar fractal macromolecule is comprised of bisterpyridine building blocks that are bound together by coordination to (36) Ru and (6) Fe ions to form a nearly planar array of increasingly larger hexagons around a hollow center. |
FILED | Friday, July 13, 2012 |
APPL NO | 13/548664 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101) C07F 15/0053 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841468 | Thompson et al. |
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FUNDED BY |
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APPLICANT(S) | Alicia Thompson (Danvers, Massachusetts); Ana Racoveanu (Melrose, Massachusetts); David Skyler (Methuen, Massachusetts) |
ASSIGNEE(S) | Physical Sciences, Inc. (Andover, Massachusetts) |
INVENTOR(S) | Alicia Thompson (Danvers, Massachusetts); Ana Racoveanu (Melrose, Massachusetts); David Skyler (Methuen, Massachusetts) |
ABSTRACT | A method of forming an azido energetic alcohol includes converting an energetic diol to a cyclic sulfite, oxidizing the cyclic sulfite to a cyclic sulfate, and opening the cyclic sulfate. The cyclic sulfate is opened, followed by hydrolysis, to form an azido energetic alcohol. |
FILED | Wednesday, June 23, 2010 |
APPL NO | 12/821392 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 247/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
08841471 — Open metal organic frameworks with exceptional surface area and high gas storage capacity
US 08841471 | Yaghi et al. |
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FUNDED BY |
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APPLICANT(S) | Omar M. Yaghi (Los Angeles, California); Jaheon Kim (Seong-Nam, South Korea); Nakeun Ko (Incheon, South Korea); Sang Beom Choi (Daejeon, South Korea); Hiroyasu Furukawa (Los Angeles, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Foundation of Soongsil University-Industry Cooperation (Seoul, South Korea) |
INVENTOR(S) | Omar M. Yaghi (Los Angeles, California); Jaheon Kim (Seong-Nam, South Korea); Nakeun Ko (Incheon, South Korea); Sang Beom Choi (Daejeon, South Korea); Hiroyasu Furukawa (Los Angeles, California) |
ABSTRACT | The disclosure provides metal organic frameworks comprising exception porosity. |
FILED | Friday, September 24, 2010 |
APPL NO | 13/496019 |
ART UNIT | 1671 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 63/38 (20130101) C07C 63/66 (20130101) C07C 63/331 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/003 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841540 | Moczygemba et al. |
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FUNDED BY |
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APPLICANT(S) | Joshua E. Moczygemba (Wylie, Texas); James L. Bierschenk (Rowlett, Texas); Jeffrey W. Sharp (Murphy, Texas) |
ASSIGNEE(S) | Marlow Industries, Inc. (Dallas, Texas) |
INVENTOR(S) | Joshua E. Moczygemba (Wylie, Texas); James L. Bierschenk (Rowlett, Texas); Jeffrey W. Sharp (Murphy, Texas) |
ABSTRACT | In accordance with one embodiment of the present disclosure, a thermoelectric device includes a plurality of thermoelectric elements that each include a diffusion barrier. The diffusion barrier includes a refractory metal. The thermoelectric device also includes a plurality of conductors coupled to the plurality of thermoelectric elements. The plurality of conductors include aluminum. In addition, the thermoelectric device includes at least one plate coupled to the plurality of thermoelectric elements using a braze. The braze includes aluminum. |
FILED | Wednesday, August 03, 2011 |
APPL NO | 13/197260 |
ART UNIT | 1754 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/00 (20130101) B23K 1/0016 (20130101) B23K 11/16 (20130101) B23K 11/115 (20130101) B23K 26/22 (20130101) B23K 2001/12 (20130101) B23K 2201/38 (20130101) B23K 2201/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/04 (20130101) H01L 35/08 (20130101) Original (OR) Class H01L 35/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841602 | Schulte et al. |
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FUNDED BY |
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APPLICANT(S) | Reinhard W. Schulte (Grand Terrace, California); R. Ford Hurley (Loma Linda, California) |
ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
INVENTOR(S) | Reinhard W. Schulte (Grand Terrace, California); R. Ford Hurley (Loma Linda, California) |
ABSTRACT | Disclosed are systems, devices and methodologies related to calibration of an ion based imaging apparatus such as a proton computed tomography scanner. In some implementations, energy degrader plates having known water-equivalent thickness (WET) values can be introduced to an ion beam to introduce different energy degradation settings. Energy detector responses to individual ions subject to such energy degradation settings can be obtained. Such responses can be normalized and correlated to water-equivalent path lengths (WEPL) of the ions based on the known WET values. Such calibration utilizing degrader plates can be performed relatively quickly and can yield accurate WEPL values that facilitate estimation of, for example, a CT image based on relative stopping power of an object. |
FILED | Tuesday, March 06, 2012 |
APPL NO | 13/413499 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/583 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841613 | Zewail et al. |
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FUNDED BY |
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APPLICANT(S) | Ahmed H. Zewail (Pasadena, California); Oh-Hoon Kwon (Burbank, California); Omar Farghaly Mohammed Abdelsaboor (Pasadena, California); Ding-Shyue Yang (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Ahmed H. Zewail (Pasadena, California); Oh-Hoon Kwon (Burbank, California); Omar Farghaly Mohammed Abdelsaboor (Pasadena, California); Ding-Shyue Yang (Pasadena, California) |
ABSTRACT | A 4D electron tomography system includes a stage having one or more degrees of freedom, an electron source, and electron optics operable to direct electron pulses to impinge on a sample supported on the stage. A pulse of the electron pulses impinges on the sample at a first time. The system also includes a laser system and optics operable to direct optical pulses to impinge on the sample. A pulse of the optical pulses impinges on the sample at a second time. The system further includes a detector operable to receive the electron pulses passing through the sample, a controller operable to independently modify an orientation of the stage and at least one of the first time or the second time, a memory operable to store sets of images, and a processor operable to form a 4D tomographic image set from the sets of images. |
FILED | Thursday, September 16, 2010 |
APPL NO | 12/884001 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) Original (OR) Class H01J 37/228 (20130101) H01J 37/285 (20130101) H01J 2237/0432 (20130101) H01J 2237/2004 (20130101) H01J 2237/2065 (20130101) H01J 2237/2611 (20130101) H01J 2237/2803 (20130101) H01J 2237/20207 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841635 | Bergeron |
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FUNDED BY |
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APPLICANT(S) | Noah P. Bergeron (Woodford, Virginia) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Noah P. Bergeron (Woodford, Virginia) |
ABSTRACT | An indicator device for detecting high-power microwave radiation is provided, including an electrically-insulating substrate; an electrically-conductive portion disposed on the substrate; and an electroluminescence material disposed on the portion. The electroluminescence material can be zinc-cadmium-sulfide ((ZnCd)S) crystal doped with manganese (Mn) and aluminum (Al) as (ZnCd)S:Mn2+,Al3+, zinc sulfide (ZnS) crystal doped with manganese (Mn) as ZnS:Mn2+, calcium sulfide (CaS) doped with europium (Eu) as CaS:Eu2+, or strontium aluminate (SrAl2O4) doped with europium and dysprosium as (SrAl2O4):Eu2+,Dy3+. |
FILED | Tuesday, June 26, 2012 |
APPL NO | 13/533200 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841682 | Dhar et al. |
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FUNDED BY |
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APPLICANT(S) | Sarit Dhar (Cary, North Carolina); Sei-Hyung Ryu (Cary, North Carolina) |
ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
INVENTOR(S) | Sarit Dhar (Cary, North Carolina); Sei-Hyung Ryu (Cary, North Carolina) |
ABSTRACT | A metal-insulator-semiconductor field-effect transistor (MISFET) includes a SiC layer with source and drain regions of a first conductivity type spaced apart therein. A first gate insulation layer is on the SiC layer and has a net charge along an interface with the SiC layer that is the same polarity as majority carriers of the source region. A gate contact is on the first gate insulation layer over a channel region of the SiC layer between the source and drain regions. The net charge along the interface between the first gate insulation layer and the SiC layer may deplete majority carriers from an adjacent portion of the channel region between the source and drain regions in the SiC layer, which may increase the threshold voltage of the MISFET and/or increase the electron mobility therein. |
FILED | Thursday, August 27, 2009 |
APPL NO | 12/548763 |
ART UNIT | 2892 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/51 (20130101) H01L 29/78 (20130101) H01L 29/513 (20130101) H01L 29/1608 (20130101) H01L 29/66068 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841712 | Rajagopal et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Aditya Rajagopal (Irvine, California); Axel Scherer (Barnard, Vermont); Michael D. Henry (Altadena, California); Sameer Walavalkar (Studio City, California); Thomas A. Tombrello (Altadena, California); Andrew P. Homyk (South Pasadena, California) |
ABSTRACT | A field effect nano-pillar transistor has a pillar shaped gate element incorporating a biomimitec portion that provides various advantages over prior art devices. The small size of the nano-pillar transistor allows for advantageous insertion into cellular membranes, and the biomimitec character of the gate element operates as an advantageous interface for sensing small amplitude voltages such as transmembrane cell potentials. The nano-pillar transistor can be used in various embodiments to stimulate cells, to measure cell response, or to perform a combination of both actions. |
FILED | Thursday, March 28, 2013 |
APPL NO | 13/852480 |
ART UNIT | 2892 — Semiconductors/Memory |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3275 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/78 (20130101) Original (OR) Class H01L 29/66477 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841739 | Khalili Amiri et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Pedram Khalili Amiri (Los Angeles, California); Kang L. Wang (Los Angeles, California) |
ABSTRACT | Embodiments of the invention implement DIOMEJ cells. In one embodiment, a DIOMEJ cell includes: an MEJ that includes, a ferromagnetic fixed layer, a ferromagnetic free layer, and a dielectric layer interposed between said fixed and free layers, where the fixed layer is magnetically polarized in a first direction, where the free layer has a first easy axis that is aligned with the first direction, and where the MEJ is configured such that when a potential difference is applied across it, the magnetic anisotropy of the free layer is altered such that the relative strength of the magnetic anisotropy along a second easy axis that is orthogonal to the first easy axis, as compared to the strength of the magnetic anisotropy along the first easy axis, is magnified for the duration of the application of the potential difference; and a diode, where the diode and the MEJ are arranged in series. |
FILED | Monday, September 09, 2013 |
APPL NO | 14/021916 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/226 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841756 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
INVENTOR(S) | Seung-Chang Lee (Albuquerque, New Mexico); Steven R. J. Brueck (Albuquerque, New Mexico) |
ABSTRACT | Methods for forming {110} type facets on a (001) oriented substrate of Group III-V compounds and Group IV semiconductors using selective epitaxial growth is provided. The methods include forming a dielectric film on a (100) substrate. The dielectric film can then be patterned to expose a portion of the substrate and to form a substrate-dielectric film boundary substantially parallel to a <110> direction. A {110} type sidewall facet can then be formed by epitaxially growing a semiconductor layer on the exposed portion of the substrate and the dielectric film. |
FILED | Thursday, August 28, 2008 |
APPL NO | 12/200139 |
ART UNIT | 2896 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02373 (20130101) H01L 21/02387 (20130101) H01L 21/02433 (20130101) H01L 21/02609 (20130101) H01L 21/02642 (20130101) Original (OR) Class H01L 33/007 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841764 | Poletto et al. |
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FUNDED BY |
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APPLICANT(S) | Stefano Poletto (West Harrison, New York); Chad T. Rigetti (Somers, New York); Matthias Steffen (Cortlandt Manor, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Stefano Poletto (West Harrison, New York); Chad T. Rigetti (Somers, New York); Matthias Steffen (Cortlandt Manor, New York) |
ABSTRACT | A quantum electronic circuit device includes a housing having an internal resonant cavity, a qubit disposed within a volume of the internal resonant cavity and a non-superconducting metallic material mechanically and thermally coupled to the qubit within the internal resonant cavity and contiguously extending to the exterior of the housing. |
FILED | Tuesday, January 31, 2012 |
APPL NO | 13/362366 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Active solid-state devices 257/712 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841818 | Marathe et al. |
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FUNDED BY |
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APPLICANT(S) | Radhika Marathe (Cambridge, Massachusetts); Dana Weinstein (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Radhika Marathe (Cambridge, Massachusetts); Dana Weinstein (Cambridge, Massachusetts) |
ABSTRACT | An piezoelectric electromechanical transistor has first and second terminals formed in a semiconductor region, a gate and a piezoelectric region between the gate and the semiconductor region. The piezoelectric region may be configured to drive the semiconductor region to vibrate in response to a signal applied to the gate. The transistor may be configured to produce a signal at the first terminal at least partially based on vibration of the semiconductor region. |
FILED | Friday, August 12, 2011 |
APPL NO | 13/209208 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/84 (20130101) H01L 29/517 (20130101) H01L 29/518 (20130101) H01L 29/7842 (20130101) H01L 41/0986 (20130101) Original (OR) Class H01L 41/1132 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841867 | Gilgenbach et al. |
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FUNDED BY |
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APPLICANT(S) | Ronald M. Gilgenbach (Ann Arbor, Michigan); Yue-Ying Lau (Potomac, Maryland); David M. French (Ann Arbor, Michigan); Brad W. Hoff (Alburquerque, New Mexico); John Luginsland (Ithaca, New York); Matthew Franzi (Chazy, New York) |
ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Ronald M. Gilgenbach (Ann Arbor, Michigan); Yue-Ying Lau (Potomac, Maryland); David M. French (Ann Arbor, Michigan); Brad W. Hoff (Alburquerque, New Mexico); John Luginsland (Ithaca, New York); Matthew Franzi (Chazy, New York) |
ABSTRACT | A crossed field device, such as a magnetron or crossed field amplifier, that includes a cathode, an anode, one or more magnetic elements, and one or more extraction elements. In one embodiment, the crossed field device includes an annular cathode and anode that are axially spaced from one another such that the device produces an axial electric (E) field and a radial magnetic (B) field. In another embodiment, the crossed field device includes an oval-shaped cathode and anode that are radially spaced from one another such that the device produces a radial electric (E) field and an axial magnetic (B) field. The crossed field device may produce electromagnetic (EM) emissions having a frequency ranging from megahertz (MHz) to terahertz (THz), and may be used in one of a number of different applications. |
FILED | Friday, August 20, 2010 |
APPL NO | 12/860336 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 23/02 (20130101) H01J 25/42 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842040 | Dorsey et al. |
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FUNDED BY |
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APPLICANT(S) | W Mark Dorsey (Elkridge, Maryland); Rashmi Mital (Lorton, Virginia); Mark G Parent (Port Tobacco, Maryland); Doug Taylor (Indian Head, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | W Mark Dorsey (Elkridge, Maryland); Rashmi Mital (Lorton, Virginia); Mark G Parent (Port Tobacco, Maryland); Doug Taylor (Indian Head, Maryland) |
ABSTRACT | A phased array antenna includes a plurality of subarrays, and each subarray includes a panel, a plurality of primary antenna elements positioned on the panel, and at least one pair of sensor antenna elements positioned along a perimeter of the panel. One of the sensor antenna elements is a transmitting sensor antenna element and the other sensor antenna element is a receiving sensor antenna element. Changes in the mutual coupling between the two high frequency sensor antenna elements as a function of deformation of the subarrays provides a calibration signal outside of the operational band of the array while the array is operated and without requiring external calibration sources. |
FILED | Monday, May 16, 2011 |
APPL NO | 13/108388 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4021 (20130101) Antennas, i.e Radio Aerials H01Q 3/267 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842051 | Mileski |
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FUNDED BY |
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APPLICANT(S) | Paul M. Mileski (Mystic, Connecticut) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Paul M. Mileski (Mystic, Connecticut) |
ABSTRACT | The invention is a buoyant cable antenna that is towed on the surface of a body of water by a submerged underwater vehicle to allow communication coverage in an omnidirectional pattern in the VHF frequency range and that is also compatible with existing buoyant cable antenna deployment and retrieval systems. The antenna of the present invention comprises a floating cable having four identical antenna elements that are arranged in a cross configuration. The antenna is designed with a system of four shielded inductor units connected in series with the antenna elements to reduce the losses to seawater by the submerged elements and to tune the exposed vertical element and its feed-cable capacitance to resonance which results in greatly increased radiated power at the design frequency of approximately 10-30 MHz. |
FILED | Friday, September 28, 2012 |
APPL NO | 13/630770 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Communications: Radio wave antennas 343/709 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842281 | Ruffin et al. |
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FUNDED BY |
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APPLICANT(S) | Paul B. Ruffin (Harvest, Alabama); Eugene Edwards (Huntsville, Alabama); Christina L. Brantley (Huntsville, Alabama); Fang Luo (State College, Pennsylvania) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Paul B. Ruffin (Harvest, Alabama); Eugene Edwards (Huntsville, Alabama); Christina L. Brantley (Huntsville, Alabama); Fang Luo (State College, Pennsylvania) |
ABSTRACT | A spectrometric system, including: a solid rocket fuel; an illuminating source including at least two wavelengths within a spectral range from 100 nm to 200,000 nm, a first wavelength or range of wavelengths having a distinguishably greater or lesser absorbance for the stabilizer than for components of the propellant, and a second wavelength or range of wavelengths having an absorbance for the stabilizer not distinguishably different than the absorbance for the components of the propellant, an illuminating fiber to illuminate a surface of a solid rocket fuel; a collecting fiber to collect back scattered, reflected or transmitted light being given off from the surface of the solid rocket fuel; and a spectrometer to determine the light intensities of the two wavelengths of the back scattered, reflected or transmitted light collected. |
FILED | Thursday, July 19, 2012 |
APPL NO | 13/553104 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) Original (OR) Class G01N 21/3151 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842361 | Manzur |
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FUNDED BY |
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APPLICANT(S) | Tariq Manzur (Lincoln, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Tariq Manzur (Lincoln, Rhode Island) |
ABSTRACT | A mode-locked laser amplifier utilizing free-space optical feedback is provided. The amplifier may tap a portion of the input laser signal and tap a portion of the output laser signal, combine the input and output samples in a free-space coupler to form a feedback laser signal, and couple the feedback laser signal back to the input laser signal. The free-space coupler suppresses higher order modes of the output laser signal. The free-space coupler can be tunable to permit selection of the operating mode of the amplifier. A plurality of amplifiers can be utilized to form a multi-stage mode-locked amplifier system. The composite feedback signal can be coupled back to each amplifier stage to lock the operating mode. |
FILED | Tuesday, March 25, 2014 |
APPL NO | 14/224358 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Optical: Systems and elements 359/340 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842497 | Ruffa |
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FUNDED BY |
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APPLICANT(S) | Anthony A. Ruffa (Hope Valley, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Anthony A. Ruffa (Hope Valley, Rhode Island) |
ABSTRACT | The invention is a method directed towards measuring differences in sounds, temperatures and pressures detected within a marine mammal, then analyzing the data to better understand the activities and behavior of the marine mammal. Wherein a buoyant capsule having a hydrophone, a temperature sensor, a pressure sensor, a memory chip, a radio frequency (RF) generator (or other means to enable its detection), software and a battery enclosed within a shell is disposed into a body of water. After a marine mammal ingests the capsule, the capsule is activated after which pressure data and sound data is detected, including sonar transmitted by a monitoring ship. The data is saved on the memory chip for recovery. |
FILED | Friday, July 27, 2012 |
APPL NO | 13/560558 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/131 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842498 | Cahalan et al. |
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FUNDED BY |
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APPLICANT(S) | Dennis Cahalan (Longmont, Colorado); Ted Noonan (Louisville, Colorado); Michel Hendricks (Boulder, Colorado); Jeffrey Croghan (Longmont, Colorado) |
ASSIGNEE(S) | Ceebus Technologies LLC (Boulder, Colorado) |
INVENTOR(S) | Dennis Cahalan (Longmont, Colorado); Ted Noonan (Louisville, Colorado); Michel Hendricks (Boulder, Colorado); Jeffrey Croghan (Longmont, Colorado) |
ABSTRACT | An underwater communication system comprises a plurality of location and messaging units for sending and receiving ultrasonic energy through water. In accordance with one aspect, each of the location and messaging units comprising an array of four ultrasonic transducers positioned such that they define a generally tetrahedral shape, a transceiver adapted to generate a code element, generate a data element, generate a modulation element, and combine the code element, the data element and the modulation element into an analog wave form. The system is further adapted to transmit the analog wave form through each of the four ultrasonic transducers and receive the analog wave-form generated by at least one of the location and messaging units. |
FILED | Thursday, April 12, 2012 |
APPL NO | 13/445108 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842688 | Vahdat et al. |
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FUNDED BY |
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APPLICANT(S) | Amin Vahdat (Poway, California); Nathan Farrington (La Jolla, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Amin Vahdat (Poway, California); Nathan Farrington (La Jolla, California) |
ABSTRACT | High speed switching networks can be created with a minimum of cabling complexity using pod switches that are connected to a core switch array. Each pod switch can include line cards arranged in parallel connecting on one side of a midplane circuit board that is orthogonal to the line cards and uplink cards also arranged in parallel connecting on an opposite side of the midplane circuit board. The uplink cards are orthogonal to both the midplane circuit board and to the line cards. Each line card provides links to computing nodes. The uplink cards connect to the core switch array. A simplified novel Ethernet extension protocol can be used in conjunction with the described hardware. Systems, methods, techniques, and articles of manufacture are also described. |
FILED | Wednesday, January 20, 2010 |
APPL NO | 13/143994 |
ART UNIT | 2469 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 49/40 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842948 | Mazumder et al. |
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FUNDED BY |
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APPLICANT(S) | Pinaki Mazumder (Ann Arbor, Michigan); Kyungju Song (Ann Arbor, Michigan) |
ASSIGNEE(S) | Pinaki Mazumder (Ann Arbor, Michigan) |
INVENTOR(S) | Pinaki Mazumder (Ann Arbor, Michigan); Kyungju Song (Ann Arbor, Michigan) |
ABSTRACT | A terahertz (THz) switch consisting of perfect conductor metamaterials is discussed in this invention. Specifically, we have built a THz logic block by combining two double-sided corrugated waveguides capable of slowing down the electromagnetic waves in the THz regime with a sub-wavelength cavity, having one or more grooves with shorter height than the grooves of the periodic corrugated waveguide. This new type of THz structure is called as the waveguide-cavity-waveguide (WCW). The new invention is based on our mathematical modeling and experimentation that confirms a strong electromagnetic field accumulation inside the tiny cavity which can confine EM field for a long time within a very small effective volume (Veff) to provide high quality (Q) factor. Therefore, an efficient THz switch can be designed to achieve ON-OFF switching functionality by modulating the refractive index n or extinction coefficient α inside the switching junction. The dimensions of the periodic structure and cavity can be optimized to apply the invention to slow-EM wave devices working at other frequencies in the EM spectrum including the microwave and outside the THz domain which is generally accepted as from 0.3 THz to 3 THz. |
FILED | Tuesday, May 08, 2012 |
APPL NO | 13/466702 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/35 (20130101) Original (OR) Class G02B 6/1226 (20130101) G02B 6/29322 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843126 | Richard |
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FUNDED BY |
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APPLICANT(S) | Curtis Z. Richard (Middletown, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Curtis Z. Richard (Middletown, Rhode Island) |
ABSTRACT | A programmable device generates a test signal indicative of a RF signal and receives a processed test signal indicative of the test signal after processing thereof by one of a RF transmission system and a RF receiving system. The programmable device performs a comparison between the processed test signal and calibration data, and generates a report based on the comparison. A hardwire signal router provides the test signal to one of the RF transmission system and the RF receiving system, and provides the processed test signal to the programmable device. The router includes a first switching mechanism and a second switching mechanism operating in a coordinated fashion to define one of a first state for testing the RF transmission system and a second state for testing the RF receiving system. |
FILED | Friday, August 03, 2012 |
APPL NO | 13/566418 |
ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Telecommunications 455/423 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843248 | Dunn et al. |
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FUNDED BY |
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APPLICANT(S) | Steven A. Dunn (Livermore, California); Andrew P. Imbrie (Santa Clara, California); Andrew A. Myers (Sunnyvale, California) |
ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
INVENTOR(S) | Steven A. Dunn (Livermore, California); Andrew P. Imbrie (Santa Clara, California); Andrew A. Myers (Sunnyvale, California) |
ABSTRACT | System and methods for managing boundaries of a vehicle being guided toward a target are provided. In some aspects, a system includes a first gate module configured to receive primary positional information of the vehicle and secondary positional information of the vehicle, to compare the primary positional information with the secondary positional information, and to generate a first pass indicator or a first fail indicator based on the comparison. The system also includes a first boundary module configured to confine navigation of the vehicle to within one of a plurality of termination boundaries based on which of the first pass indicator and the first fail indicator is generated. Each of the plurality of termination boundaries is confined within a range boundary of the vehicle and offset from the range boundary at a different magnitude. |
FILED | Tuesday, April 19, 2011 |
APPL NO | 13/090161 |
ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/3 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843305 | Jacob |
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FUNDED BY |
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APPLICANT(S) | Robert Jacob (Lusby, Maryland) |
ASSIGNEE(S) | The United States of America represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Robert Jacob (Lusby, Maryland) |
ABSTRACT | A system and method for providing independent weapon launch or release control for an unmanned or autonomous vehicle by ensuring the vehicle is within its weapon launch area using geographic position information from a navigational source such as GPS, comparing the position of the vehicle to the weapon's launch boundaries, and arming or disarming the vehicle's weapon launch capability based on its location relative to the weapon launch area. |
FILED | Thursday, April 25, 2013 |
APPL NO | 13/870488 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/00 (20130101) Original (OR) Class F42C 15/40 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843342 | Vold et al. |
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FUNDED BY |
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APPLICANT(S) | Havard I. Vold (Charleston, South Carolina); Paul G. Bremner (Del Mar, California); Parthiv N. Shah (San Diego, California) |
ASSIGNEE(S) | ATA Engineering, Inc. (San Diego, California) |
INVENTOR(S) | Havard I. Vold (Charleston, South Carolina); Paul G. Bremner (Del Mar, California); Parthiv N. Shah (San Diego, California) |
ABSTRACT | A continuous scanning method employs one or more moveable sensors and one or more reference sensors deployed in the environment around a test subject. Each sensor is configured to sense an attribute of the test subject (e.g., sound energy, infrared energy, etc.) while continuously moving along a path and recording the sensed attribute, the position, and the orientation of each of the moveable sensors and each of the reference sensors. The system then constructs a set of transfer functions corresponding to points in space between the moveable sensors, wherein each of the transfer functions relates the test data of the moveable sensors to the test data of the reference sensors. In this way, a graphical representation of the attribute in the vicinity of test subject can be produced. |
FILED | Thursday, December 30, 2010 |
APPL NO | 12/982297 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Holographic Processes or Apparatus G03H 1/08 (20130101) G03H 1/0866 (20130101) G03H 3/00 (20130101) Original (OR) Class G03H 2227/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843425 | Modha |
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FUNDED BY |
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APPLICANT(S) | Dharmendra S. Modha (San Jose, California) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Dharmendra S. Modha (San Jose, California) |
ABSTRACT | Hierarchical routing for two-way information flow and structural plasticity in a neural network is provided. In one embodiment the network includes multiple core modules, wherein each core module has a plurality of incoming connections with predetermined addresses. Each core module also has a plurality of outgoing connections such that each outgoing connection targets an incoming connection in a core module among the multiple core modules. The network also has a routing system that selectively routes signals among the core modules based on a reconfigurable hierarchical organization of the core modules. The network approximates a fully connected network such that each outgoing connection on any core module can target and reach any incoming connection on any core module without requiring a fully connected network. The routing system provides two-way information flow between neurons utilizing hierarchical routing. |
FILED | Friday, July 29, 2011 |
APPL NO | 13/194596 |
ART UNIT | 2129 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843890 | Frenkiel et al. |
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FUNDED BY |
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APPLICANT(S) | Andrew Lawrence Frenkiel (Irvington, New York); Bugra Gedik (White Plains, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Andrew Lawrence Frenkiel (Irvington, New York); Bugra Gedik (White Plains, New York) |
ABSTRACT | A computer system for integrating existing source code into target source code, the computer system including a change point mapper that outputs a plurality of suggested candidate mappings between a change point of the existing source code and a plurality of change points of the target source code, a change point transformer that receives the plurality of suggested candidate mappings and outputs an updated existing source code, the change point transformer being configured to automatically update the existing source code based on a selected candidate mapping of the plurality of suggested candidate mappings, and a change point transplanter being configured to insert the updated existing source code into the target source code. |
FILED | Thursday, May 10, 2012 |
APPL NO | 13/468883 |
ART UNIT | 2192 — Interprocess Communication and Software Development |
CURRENT CPC | Data processing: Software development, installation, and management 717/120 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843904 | Andrade et al. |
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FUNDED BY |
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APPLICANT(S) | Henrique Andrade (Croton-on-Hudson, New York); Judah M. Diament (Bergenfield, New Jersey); Bugra Gedik (White Plains, New York); Anton V. Riabov (Ossining, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Henrique Andrade (Croton-on-Hudson, New York); Judah M. Diament (Bergenfield, New Jersey); Bugra Gedik (White Plains, New York); Anton V. Riabov (Ossining, New York) |
ABSTRACT | Architecture-dependent assets are automatically built and retargeted. An asset originally built for one architecture is downloaded and automatically retargeted on another architecture. This automatically retargeting may be performed on demand, at runtime. |
FILED | Tuesday, January 26, 2010 |
APPL NO | 12/693554 |
ART UNIT | 2192 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 8/60 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08844032 | Saidi et al. |
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FUNDED BY |
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APPLICANT(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ABSTRACT | A method and system for application-based monitoring and enforcement of security, privacy, performance and/or other policies on a mobile device includes incorporating monitoring and policy enforcement code into a previously un-monitored software application package that is installable on a mobile device, and executing the monitoring and policy enforcement code during normal use of the software application by a user of the mobile device. |
FILED | Friday, March 02, 2012 |
APPL NO | 13/411200 |
ART UNIT | 2496 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1408 (20130101) H04L 63/1416 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08844033 | Song et al. |
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FUNDED BY |
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APPLICANT(S) | Yingbo Song (Hazlet, New Jersey); Angelos D. Keromytis (New York, New York); Salvatore J. Stolfo (Ridgewood, New Jersey) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Yingbo Song (Hazlet, New Jersey); Angelos D. Keromytis (New York, New York); Salvatore J. Stolfo (Ridgewood, New Jersey) |
ABSTRACT | Systems, methods, and media for detecting network anomalies are provided. In some embodiments, a training dataset of communication protocol messages having argument strings is received. The content and structure associated with each of the argument strings is determined and a probabilistic model is trained using the determined content and structure of each of the argument strings. A communication protocol message having an argument string that is transmitted from a first processor to a second processor across a computer network is received. The received communication protocol message is compared to the probabilistic model and then it is determined whether the communication protocol message is anomalous. |
FILED | Wednesday, May 27, 2009 |
APPL NO | 12/994550 |
ART UNIT | 2493 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class H04L 63/1466 (20130101) H04L 67/02 (20130101) H04L 69/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08844036 | Saidi et al. |
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FUNDED BY |
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APPLICANT(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ABSTRACT | A method and system for application-based monitoring and enforcement of security, privacy, performance and/or other policies on a mobile device includes incorporating monitoring and policy enforcement code into a previously un-monitored software application package that is installable on a mobile device, and executing the monitoring and policy enforcement code during normal use of the software application by a user of the mobile device. |
FILED | Friday, March 02, 2012 |
APPL NO | 13/411072 |
ART UNIT | 2496 — Cryptography and Security |
CURRENT CPC | Information security 726/23 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 08839659 | Xiao |
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FUNDED BY |
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APPLICANT(S) | Zhili Xiao (Naperville, Illinois) |
ASSIGNEE(S) | Board of Trustees of Northern Illinois University (DeKalb, Illinois) |
INVENTOR(S) | Zhili Xiao (Naperville, Illinois) |
ABSTRACT | A network of nanowires may be used for a sensor. The nanowires are metallic, each nanowire has a thickness of at most 20 nm, and each nanowire has a width of at most 20 nm. The sensor may include nanowires comprising Pd, and the sensor may sense a change in hydrogen concentration from 0 to 100%. A device may include the hydrogen sensor, such as a vehicle, a fuel cell, a hydrogen storage tank, a facility for manufacturing steel, or a facility for refining petroleum products. |
FILED | Monday, September 26, 2011 |
APPL NO | 13/245674 |
ART UNIT | 2856 — Printing/Measuring and Testing |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) Original (OR) Class G01N 33/005 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/81 (20130101) Y10S 977/762 (20130101) Y10S 977/932 (20130101) Y10S 977/948 (20130101) Y10S 977/957 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08839704 | Baum |
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FUNDED BY |
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APPLICANT(S) | Dennis W. Baum (Danville, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
INVENTOR(S) | Dennis W. Baum (Danville, California) |
ABSTRACT | A system that may be used as an initiation disruption system (IDS) according to one embodiment includes an explosive charge; a plurality of particles in a layer at least partially surrounding the explosive charge; and a fire suppressant adjacent the plurality of particles. A method for disabling an object according to one embodiment includes placing the system as recited above near an object; and causing the explosive charge to initiate, thereby applying mechanical loading to the object such that the object becomes disabled. Additional systems and methods are also presented. A device according to another embodiment includes a plurality of particles bound by a binder thereby defining a sidewall having an interior for receiving an explosive; and a fire suppressant adjacent the plurality of particles and binder. Additional systems and methods are also presented. |
FILED | Tuesday, May 31, 2011 |
APPL NO | 13/149802 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Blasting F42D 5/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08839750 | Brennan et al. |
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FUNDED BY |
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APPLICANT(S) | Daniel G. Brennan (Brighton, Michigan); Craig D. Marriott (Clawson, Michigan); Joel Cowgill (White Lake, Michigan); Matthew A. Wiles (Royal Oak, Michigan); Kenneth James Patton (Howell, Michigan) |
ASSIGNEE(S) | GM Global Technology Operations LLC (, None) |
INVENTOR(S) | Daniel G. Brennan (Brighton, Michigan); Craig D. Marriott (Clawson, Michigan); Joel Cowgill (White Lake, Michigan); Matthew A. Wiles (Royal Oak, Michigan); Kenneth James Patton (Howell, Michigan) |
ABSTRACT | A control system for an engine includes a first lift control module and a second lift control module. The first lift control module increases lift of M valves of the engine to a predetermined valve lift during a period before disabling or re-enabling N valves of the engine. The second lift control module decreases the lift of the M valves to a desired valve lift during a period after enabling or re-enabling the N valves of the engine, wherein N and M are integers greater than or equal to one. |
FILED | Friday, October 22, 2010 |
APPL NO | 12/910212 |
ART UNIT | 3748 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Cyclically Operating Valves for Machines or Engines F01L 9/02 (20130101) F01L 13/0005 (20130101) F01L 13/0015 (20130101) F01L 2800/08 (20130101) Controlling Combustion Engines F02D 13/08 (20130101) F02D 13/0207 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Transportation Y02T 10/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840374 | Garcia-Crespo et al. |
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FUNDED BY |
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APPLICANT(S) | Andres Jose Garcia-Crespo (Greenville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Andres Jose Garcia-Crespo (Greenville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina) |
ABSTRACT | An adaptor assembly for coupling a blade root of a turbine blade to a root slot of a rotor disk is described. The adaptor assembly includes a turbine blade having a blade root and an adaptor body having an adaptor root. The adaptor body defines a slot having an open end configured to receive the blade root of the turbine blade such that the adaptor root of the adaptor body and the blade root of the turbine blade are adjacent to one another when the blade root of the turbine blade is positioned within the slot. Both the adaptor root of the adaptor body and the blade root of the turbine blade are configured to be received within the root slot of the rotor disk. |
FILED | Wednesday, October 12, 2011 |
APPL NO | 13/271635 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/3007 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840706 | Srinivasachar |
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FUNDED BY |
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APPLICANT(S) | Srivats Srinivasachar (Sturbridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Srivats Srinivasachar (Sturbridge, Massachusetts) |
ABSTRACT | A composition, process and system for capturing carbon dioxide from a combustion gas stream. The composition has a particulate porous support medium that has a high volume of pores, an alkaline component distributed within the pores and on the surface of the support medium, and water adsorbed on the alkaline component, wherein the proportion of water in the composition is between about 5% and about 35% by weight of the composition. The process and system contemplates contacting the sorbent and the flowing gas stream together at a temperature and for a time such that some water remains adsorbed in the alkaline component when the contact of the sorbent with the flowing gas ceases. |
FILED | Wednesday, May 23, 2012 |
APPL NO | 13/478184 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/139 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840724 | Grigorian et al. |
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FUNDED BY |
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APPLICANT(S) | Leonid Grigorian (Raymond, Ohio); Louis Hornyak (Evergreen, Colorado); Anne C. Dillon (Boulder, Colorado); Michael J. Heben (Denver, Colorado) |
ASSIGNEE(S) | Honda Motor Co., Ltd. (Tokyo, Japan) |
INVENTOR(S) | Leonid Grigorian (Raymond, Ohio); Louis Hornyak (Evergreen, Colorado); Anne C. Dillon (Boulder, Colorado); Michael J. Heben (Denver, Colorado) |
ABSTRACT | The invention relates to a chemical vapor deposition process for the continuous growth of a carbon single-wall nanotube where a carbon-containing gas composition is contacted with a porous membrane and decomposed in the presence of a catalyst to grow single-wall carbon nanotube material. A pressure differential exists across the porous membrane such that the pressure on one side of the membrane is less than that on the other side of the membrane. The single-wall carbon nanotube growth may occur predominately on the low-pressure side of the membrane or, in a different embodiment of the invention, may occur predominately in between the catalyst and the membrane. The invention also relates to an apparatus used with the carbon vapor deposition process. |
FILED | Tuesday, September 23, 2008 |
APPL NO | 12/236144 |
ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/45576 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/18 (20130101) Original (OR) Class C30B 29/602 (20130101) C30B 35/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08840859 | Bourcier et al. |
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FUNDED BY |
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APPLICANT(S) | William L. Bourcier (Livermore, California); Carol J. Bruton (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | William L. Bourcier (Livermore, California); Carol J. Bruton (Livermore, California) |
ABSTRACT | A method of producing silica from geothermal fluid containing low concentration of the silica of less than 275 ppm includes the steps of treating the geothermal fluid containing the silica by reverse osmosis treatment thereby producing a concentrated fluid containing the silica, seasoning the concentrated fluid thereby producing a slurry having precipitated colloids containing the silica, and separating the silica from the slurry. |
FILED | Wednesday, September 03, 2008 |
APPL NO | 12/203250 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemistry of inorganic compounds 423/339 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841090 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Min Zhang (Lakewood, Colorado); Arjun Singh (Lakewood, Colorado); Pirkko Suominen (Minnetonka, Minnesota); Eric Knoshaug (Golden, Colorado); Mary Ann Franden (Centennial, Colorado); Eric Jarvis (Boulder, Colorado) |
ABSTRACT | An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains. |
FILED | Thursday, January 17, 2013 |
APPL NO | 13/744023 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841152 | Bahlke et al. |
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FUNDED BY |
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APPLICANT(S) | Matthias Erhard Bahlke (Cambridge, Massachusetts); Marc A. Baldo (Lexington, Massachusetts); Hiroshi Antonio Mendoza (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Matthias Erhard Bahlke (Cambridge, Massachusetts); Marc A. Baldo (Lexington, Massachusetts); Hiroshi Antonio Mendoza (Cambridge, Massachusetts) |
ABSTRACT | Method for making a patterned thin film of an organic semiconductor. The method includes condensing a resist gas into a solid film onto a substrate cooled to a temperature below the condensation point of the resist gas. The condensed solid film is heated selectively with a patterned stamp to cause local direct sublimation from solid to vapor of selected portions of the solid film thereby creating a patterned resist film. An organic semiconductor film is coated on the patterned resist film and the patterned resist film is heated to cause it to sublime away and to lift off because of the phase change. |
FILED | Monday, May 07, 2012 |
APPL NO | 13/465065 |
ART UNIT | 2895 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0016 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841451 | Newkome et al. |
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FUNDED BY |
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APPLICANT(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Chagrin Falls, Ohio) |
ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
INVENTOR(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Chagrin Falls, Ohio) |
ABSTRACT | The invention relates to the formation of synthesized fractal constructs and the methods of chemical self-assembly for the preparation of a non-dendritic, nano-scale, fractal constructs or molecules. More particularly, the invention relates to fractal constructs formed by molecular self-assembly, to create synthetic, nanometer-scale fractal shapes. In an embodiment, a nanoscale Sierpinski hexagonal gasket is formed. This non-dendritic, perfectly self-similar fractal macromolecule is comprised of bisterpyridine building blocks that are bound together by coordination to (36) Ru and (6) Fe ions to form a nearly planar array of increasingly larger hexagons around a hollow center. |
FILED | Friday, July 13, 2012 |
APPL NO | 13/548664 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101) C07F 15/0053 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841495 | Marker et al. |
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FUNDED BY |
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APPLICANT(S) | Terry L. Marker (Palos Heights, Illinois); Larry G. Felix (Pelham, Alabama); Martin B. Linck (Oak Park, Israel); Michael J. Roberts (Itasca, Illinois) |
ASSIGNEE(S) | Gas Technology Institute (Des Plaines, Illinois) |
INVENTOR(S) | Terry L. Marker (Palos Heights, Illinois); Larry G. Felix (Pelham, Alabama); Martin B. Linck (Oak Park, Israel); Michael J. Roberts (Itasca, Illinois) |
ABSTRACT | This invention relates to a process for thermochemically transforming biomass or other oxygenated feedstocks into high quality liquid hydrocarbon fuels. In particular, a catalytic hydropyrolysis reactor, containing a deep bed of fluidized catalyst particles is utilized to accept particles of biomass or other oxygenated feedstocks that are significantly smaller than the particles of catalyst in the fluidized bed. The reactor features an insert or other structure disposed within the reactor vessel that inhibits slugging of the bed and thereby minimizes attrition of the catalyst. Within the bed, the biomass feedstock is converted into a vapor-phase product, containing hydrocarbon molecules and other process vapors, and an entrained solid char product, which is separated from the vapor stream after the vapor stream has been exhausted from the top of the reactor. When the product vapor stream is cooled to ambient temperatures, a significant proportion of the hydrocarbons in the product vapor stream can be recovered as a liquid stream of hydrophobic hydrocarbons, with properties consistent with those of gasoline, kerosene, and diesel fuel. Separate streams of gasoline, kerosene, and diesel fuel may also be obtained, either via selective condensation of each type of fuel, or via later distillation of the combined hydrocarbon liquid. |
FILED | Monday, April 18, 2011 |
APPL NO | 13/089010 |
ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/34 (20130101) B01J 8/1809 (20130101) B01J 23/755 (20130101) B01J 23/882 (20130101) B01J 2208/00061 (20130101) B01J 2208/0084 (20130101) B01J 2208/00115 (20130101) B01J 2208/00548 (20130101) B01J 2219/00252 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/06 (20130101) C10G 1/10 (20130101) Original (OR) Class C10G 1/086 (20130101) C10G 3/45 (20130101) C10G 3/46 (20130101) C10G 3/50 (20130101) C10G 3/57 (20130101) C10G 2300/202 (20130101) C10G 2300/1003 (20130101) C10G 2300/1014 (20130101) C10G 2300/1018 (20130101) C10G 2400/02 (20130101) C10G 2400/04 (20130101) C10G 2400/08 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841540 | Moczygemba et al. |
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FUNDED BY |
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APPLICANT(S) | Joshua E. Moczygemba (Wylie, Texas); James L. Bierschenk (Rowlett, Texas); Jeffrey W. Sharp (Murphy, Texas) |
ASSIGNEE(S) | Marlow Industries, Inc. (Dallas, Texas) |
INVENTOR(S) | Joshua E. Moczygemba (Wylie, Texas); James L. Bierschenk (Rowlett, Texas); Jeffrey W. Sharp (Murphy, Texas) |
ABSTRACT | In accordance with one embodiment of the present disclosure, a thermoelectric device includes a plurality of thermoelectric elements that each include a diffusion barrier. The diffusion barrier includes a refractory metal. The thermoelectric device also includes a plurality of conductors coupled to the plurality of thermoelectric elements. The plurality of conductors include aluminum. In addition, the thermoelectric device includes at least one plate coupled to the plurality of thermoelectric elements using a braze. The braze includes aluminum. |
FILED | Wednesday, August 03, 2011 |
APPL NO | 13/197260 |
ART UNIT | 1754 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/00 (20130101) B23K 1/0016 (20130101) B23K 11/16 (20130101) B23K 11/115 (20130101) B23K 26/22 (20130101) B23K 2001/12 (20130101) B23K 2201/38 (20130101) B23K 2201/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/04 (20130101) H01L 35/08 (20130101) Original (OR) Class H01L 35/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841548 | Giebink et al. |
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FUNDED BY |
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APPLICANT(S) | Noel Christopher Giebink (Downers Grove, Illinois); Gary P. Wiederrecht (Elmhurst, Illinois); Michael R. Wasielewski (Glenview, Illinois) |
ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Noel Christopher Giebink (Downers Grove, Illinois); Gary P. Wiederrecht (Elmhurst, Illinois); Michael R. Wasielewski (Glenview, Illinois) |
ABSTRACT | An optical system and method to overcome luminescent solar concentrator inefficiencies by resonance-shifting, in which sharply directed emission from a bi-layer cavity into a glass substrate returns to interact with the cavity off-resonance at each subsequent reflection, significantly reducing reabsorption loss en route to the edges. In one embodiment, the system comprises a luminescent solar concentrator comprising a transparent substrate, a luminescent film having a variable thickness; and a low refractive index layer disposed between the transparent substrate and the luminescent film. |
FILED | Friday, August 26, 2011 |
APPL NO | 13/199323 |
ART UNIT | 1758 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841549 | Vardeny et al. |
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FUNDED BY |
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APPLICANT(S) | Zee valentine Vardeny (Salt Lake City, Utah); Alex Ndobe (Ottawa, Canada) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Zee valentine Vardeny (Salt Lake City, Utah); Alex Ndobe (Ottawa, Canada) |
ABSTRACT | An organic spintronic photovoltaic device (100) having an organic electron active layer (102) functionally associated with a pair of electrodes (104, 106). The organic electron active layer (102) can include a spin active molecular radical distributed in the active layer (102) which increases spin-lattice relaxation rates within the active layer (102). The increased spin lattice relaxation rate can also influence the efficiency of OLED and charge mobility in FET devices. |
FILED | Monday, September 28, 2009 |
APPL NO | 13/123493 |
ART UNIT | 1757 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/005 (20130101) H01L 51/0036 (20130101) H01L 51/0037 (20130101) H01L 51/0047 (20130101) H01L 51/424 (20130101) Original (OR) Class H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841592 | Ho et al. |
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FUNDED BY |
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APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
INVENTOR(S) | Clifford K. Ho (Albuquerque, New Mexico); Cianan Alexander Sims (Albuquerque, New Mexico) |
ABSTRACT | Technologies pertaining to determining when glare will be perceived by a hypothetical observer from a glare source and the intensity of glare that will be perceived by the hypothetical observer from the glare source are described herein. A first location of a potential source of solar glare is received, and a second location of the hypothetical observer is received. Based upon such locations, including respective elevations, and known positions of the sun over time, a determination as to when the hypothetical observer will perceive glare from the potential source of solar glare is made. Subsequently, an amount of irradiance entering the eye of the hypothetical observer is calculated to assess potential ocular hazards. |
FILED | Tuesday, September 25, 2012 |
APPL NO | 13/626617 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Radiant energy 250/203.400 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841608 | Shvartsburg et al. |
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FUNDED BY |
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APPLICANT(S) | Alexandre A. Shvartsburg (Richland, Washington); Keqi Tang (Richland, Washington); Richard D. Smith (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Alexandre A. Shvartsburg (Richland, Washington); Keqi Tang (Richland, Washington); Richard D. Smith (Richland, Washington) |
ABSTRACT | A method for raising the resolving power, specificity, and peak capacity of conventional ion mobility spectrometry is disclosed. Ions are separated in a dynamic electric field comprising an oscillatory field wave and opposing static field, or at least two counter propagating waves with different parameters (amplitude, profile, frequency, or speed). As the functional dependencies of mean drift velocity on the ion mobility in a wave and static field or in unequal waves differ, only single species is equilibrated while others drift in either direction and are mobility-separated. An ion mobility spectrum over a limited range is then acquired by measuring ion drift times through a fixed distance inside the gas-filled enclosure. The resolving power in the vicinity of equilibrium mobility substantially exceeds that for known traveling-wave or drift-tube IMS separations, with spectra over wider ranges obtainable by stitching multiple segments. The approach also enables low-cutoff, high-cutoff, and bandpass ion mobility filters. |
FILED | Friday, April 12, 2013 |
APPL NO | 13/861511 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842703 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | Shukui Zhang (Yorktown, Virginia); Guy Wilson (Norfolk, Virginia) |
ASSIGNEE(S) | Jefferson Science Associates, LLC (Newport News, Virginia) |
INVENTOR(S) | Shukui Zhang (Yorktown, Virginia); Guy Wilson (Norfolk, Virginia) |
ABSTRACT | An apparatus and method for enhancing pulse contrast ratios for drive lasers and electron accelerators. The invention comprises a mechanical dual-shutter system wherein the shutters are placed sequentially in series in a laser beam path. Each shutter of the dual shutter system has an individually operated trigger for opening and closing the shutter. As the triggers are operated individually, the delay between opening and closing first shutter and opening and closing the second shutter is variable providing for variable differential time windows and enhancement of pulse contrast ratio. |
FILED | Monday, March 05, 2012 |
APPL NO | 13/385728 |
ART UNIT | 2828 — Semiconductors/Memory |
CURRENT CPC | Coherent light generators 372/25 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843238 | Wenzel et al. |
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FUNDED BY |
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APPLICANT(S) | Michael J. Wenzel (Oak Creek, Wisconsin); Kirk H. Drees (Cedarburg, Wisconsin) |
ASSIGNEE(S) | Johnson Controls Technology Company (Holland, Michigan) |
INVENTOR(S) | Michael J. Wenzel (Oak Creek, Wisconsin); Kirk H. Drees (Cedarburg, Wisconsin) |
ABSTRACT | Systems and methods for limiting power consumption by a heating, ventilation, and air conditioning (HVAC) subsystem of a building are shown and described. A feedback controller is used to generate a manipulated variable based on an energy use setpoint and a measured energy use. The manipulated variable may be used for adjusting the operation of an HVAC device. |
FILED | Friday, September 30, 2011 |
APPL NO | 13/251134 |
ART UNIT | 2127 — AI & Simulation/Modeling |
CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/006 (20130101) Original (OR) Class F24F 2011/0075 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1923 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843323 | Nelson |
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FUNDED BY |
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APPLICANT(S) | Eric M. Nelson (White Rock, New Mexico) |
ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Eric M. Nelson (White Rock, New Mexico) |
ABSTRACT | Complex gun code computations can be made to converge more quickly based on a selection of one or more relaxation parameters. An eigenvalue analysis is applied to error residuals to identify two error eigenvalues that are associated with respective error residuals. Relaxation values can be selected based on these eigenvalues so that error residuals associated with each can be alternately reduced in successive iterations. In some examples, relaxation values that would be unstable if used alone can be used. |
FILED | Friday, May 14, 2010 |
APPL NO | 12/780776 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/28 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 08841014 | Deshpande et al. |
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FUNDED BY |
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APPLICANT(S) | Rutooj D. Deshpande (Lexington, Kentucky); Juchuan Li (Lexington, Kentucky); Yang-Tse Cheng (Lexington, Kentucky) |
ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
INVENTOR(S) | Rutooj D. Deshpande (Lexington, Kentucky); Juchuan Li (Lexington, Kentucky); Yang-Tse Cheng (Lexington, Kentucky) |
ABSTRACT | An electrode for a lithium ion battery includes a liquid metal having a melting point that is below the operating temperature of the battery, which transforms from a liquid to a solid during lithiation, and wherein the liquid metal transforms from a solid to a liquid during delithiation. |
FILED | Friday, April 27, 2012 |
APPL NO | 13/458620 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/36 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841072 | Bazan et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Guillermo C. Bazan (Santa Barbara, California); Brent S. Gaylord (San Diego, California); Shu Wang (Beijing, China PRC) |
ABSTRACT | Methods, compositions and articles of manufacture for assaying a sample for a target polynucleotide are provided. A sample suspected of containing the target polynucleotide is contacted with a polycationic multichromophore and a sensor polynucleotide complementary to the target polynucleotide. The sensor polynucleotide comprises a signaling chromophore to receive energy from the excited multichromophore and increase emission in the presence of the target polynucleotide. The methods can be used in multiplex form. Kits comprising reagents for performing such methods are also provided. |
FILED | Thursday, November 21, 2013 |
APPL NO | 14/086532 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841170 | Fadeyev et al. |
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FUNDED BY |
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APPLICANT(S) | Vitaliy Fadeyev (Santa Cruz, California); Hartmut F. W. Sadrozinski (Palo Alto, California); Marc Christophersen (Berwyn Heights, Maryland); Bernard F. Phlips (Great Falls, Virginia) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Naval Research Laboratory (Washington, District of Columbia) |
INVENTOR(S) | Vitaliy Fadeyev (Santa Cruz, California); Hartmut F. W. Sadrozinski (Palo Alto, California); Marc Christophersen (Berwyn Heights, Maryland); Bernard F. Phlips (Great Falls, Virginia) |
ABSTRACT | A method of singulating semiconductor devices in the close proximity to active structures by controlling interface charge of semiconductor device sidewalls is provided that includes forming a scribe on a surface of a semiconductor devices, where the scribe is within 5 degrees of a crystal lattice direction of the semiconductor device, cleaving the semiconductor device along the scribe, where the devices are separated, using a coating process to coat the sidewalls of the cleaved semiconductor device with a passivation material, where the passivation material is disposed to provide a fixed charge density at a semiconductor interface of the sidewalls, and where the fixed charge density interacts with charge carriers in the bulk of the material. |
FILED | Friday, October 21, 2011 |
APPL NO | 13/879971 |
ART UNIT | 2891 — Semiconductors/Memory |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0042 (20130101) B23K 26/0057 (20130101) B23K 26/0081 (20130101) B23K 26/0087 (20130101) B23K 26/367 (20130101) B23K 26/4075 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/78 (20130101) Original (OR) Class H01L 31/1804 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841239 | Busnaina et al. |
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FUNDED BY |
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APPLICANT(S) | Ahmed A. Busnaina (Ashland, Massachusetts); Joey L. Mead (Carlisle, Massachusetts); Carol M. F. Barry (Tyngsborough, Massachusetts); Ming Wei (Lowell, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Ahmed A. Busnaina (Ashland, Massachusetts); Joey L. Mead (Carlisle, Massachusetts); Carol M. F. Barry (Tyngsborough, Massachusetts); Ming Wei (Lowell, Massachusetts) |
ABSTRACT | Nanoscale patterns prepared by lithography are used to direct the self-assembly of amphiphilic molecules to form patterned nanosubstrates having a desired distribution of chemical functional moieties. These patterns can be fabricated over a large area and require no special limitations on the chemistry the assembled amphiphiles. Hydrophilic/hydrophobic patterns can be created and used to direct the deposition of a single functional component to specific regions of the surface or to selectively assemble polymer blends to desired sites in a one step fashion with high specificity and selectivity. The selective deposition of functional moieties on a patterned surface can be based on electrostatic forces, hydrogen bonding, or hydrophobic interactions. The methods and patterned nanosubstrates of the invention can be used in the assembly of functional polymer systems, polyelectrolytes, biomolecules, conducting polymers, colloids and nanoparticles, and find wide technological applications in biosensors, biochips, photonics and electronics. |
FILED | Friday, November 21, 2008 |
APPL NO | 12/743441 |
ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/185 (20130101) B05D 3/141 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2033/0096 (20130101) G01N 2035/00158 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/00 (20130101) G03F 7/0002 (20130101) G03F 7/004 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/888 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841428 | Seeman et al. |
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FUNDED BY |
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APPLICANT(S) | Nadrian C. Seeman (New York, New York); Shiping Liao (New York, New York); James Canary (New York, New York); Hong Zhong (Brooklyn, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Nadrian C. Seeman (New York, New York); Shiping Liao (New York, New York); James Canary (New York, New York); Hong Zhong (Brooklyn, New York) |
ABSTRACT | A polynucleic acid nanomechanical device with a linear array of alternating PX-JX2 devices and nucleic acid multi-crossover motifs that facilitate the assembly of a nucleic acid strand and functions as an artificial ribosome by translating a nucleic acid signal into an unrelated nucleic acid sequence. |
FILED | Friday, July 29, 2005 |
APPL NO | 11/192401 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/1031 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class C12P 21/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841451 | Newkome et al. |
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FUNDED BY |
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APPLICANT(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Chagrin Falls, Ohio) |
ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
INVENTOR(S) | George R. Newkome (Medina, Ohio); Charles N. Moorefield (Chagrin Falls, Ohio) |
ABSTRACT | The invention relates to the formation of synthesized fractal constructs and the methods of chemical self-assembly for the preparation of a non-dendritic, nano-scale, fractal constructs or molecules. More particularly, the invention relates to fractal constructs formed by molecular self-assembly, to create synthetic, nanometer-scale fractal shapes. In an embodiment, a nanoscale Sierpinski hexagonal gasket is formed. This non-dendritic, perfectly self-similar fractal macromolecule is comprised of bisterpyridine building blocks that are bound together by coordination to (36) Ru and (6) Fe ions to form a nearly planar array of increasingly larger hexagons around a hollow center. |
FILED | Friday, July 13, 2012 |
APPL NO | 13/548664 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101) C07F 15/0053 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841460 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | State of Oregon, acting by and through the State Board of Higher Education on behalf of University of Oregon (Eugene, Oregon) |
ASSIGNEE(S) | State of Oregon Acting by and Through the State Board of Higher Education on Behalf of the University of Oregon (Igene, Oregon) |
INVENTOR(S) | Darren W. Johnson (Eugene, Oregon); Calden Carroll (Eugene, Oregon); Michael M. Haley (Eugene, Oregon); Jeff Engle (Eugene, Oregon) |
ABSTRACT | A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl. |
FILED | Friday, December 14, 2012 |
APPL NO | 13/715979 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/337 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841511 | Maliga et al. |
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FUNDED BY |
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APPLICANT(S) | Pal Maliga (East Brunswick, New Jersey); Kerry A. Lutz (Somerset, New Jersey) |
ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
INVENTOR(S) | Pal Maliga (East Brunswick, New Jersey); Kerry A. Lutz (Somerset, New Jersey) |
ABSTRACT | Compositions and methods for manipulating the plastid genome of higher plants are provided. |
FILED | Wednesday, March 03, 2004 |
APPL NO | 10/547561 |
ART UNIT | 1638 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8209 (20130101) Original (OR) Class C12N 15/8213 (20130101) C12N 15/8214 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841549 | Vardeny et al. |
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FUNDED BY |
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APPLICANT(S) | Zee valentine Vardeny (Salt Lake City, Utah); Alex Ndobe (Ottawa, Canada) |
ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
INVENTOR(S) | Zee valentine Vardeny (Salt Lake City, Utah); Alex Ndobe (Ottawa, Canada) |
ABSTRACT | An organic spintronic photovoltaic device (100) having an organic electron active layer (102) functionally associated with a pair of electrodes (104, 106). The organic electron active layer (102) can include a spin active molecular radical distributed in the active layer (102) which increases spin-lattice relaxation rates within the active layer (102). The increased spin lattice relaxation rate can also influence the efficiency of OLED and charge mobility in FET devices. |
FILED | Monday, September 28, 2009 |
APPL NO | 13/123493 |
ART UNIT | 1757 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/005 (20130101) H01L 51/0036 (20130101) H01L 51/0037 (20130101) H01L 51/0047 (20130101) H01L 51/424 (20130101) Original (OR) Class H01L 51/4253 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841613 | Zewail et al. |
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FUNDED BY |
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APPLICANT(S) | Ahmed H. Zewail (Pasadena, California); Oh-Hoon Kwon (Burbank, California); Omar Farghaly Mohammed Abdelsaboor (Pasadena, California); Ding-Shyue Yang (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Ahmed H. Zewail (Pasadena, California); Oh-Hoon Kwon (Burbank, California); Omar Farghaly Mohammed Abdelsaboor (Pasadena, California); Ding-Shyue Yang (Pasadena, California) |
ABSTRACT | A 4D electron tomography system includes a stage having one or more degrees of freedom, an electron source, and electron optics operable to direct electron pulses to impinge on a sample supported on the stage. A pulse of the electron pulses impinges on the sample at a first time. The system also includes a laser system and optics operable to direct optical pulses to impinge on the sample. A pulse of the optical pulses impinges on the sample at a second time. The system further includes a detector operable to receive the electron pulses passing through the sample, a controller operable to independently modify an orientation of the stage and at least one of the first time or the second time, a memory operable to store sets of images, and a processor operable to form a 4D tomographic image set from the sets of images. |
FILED | Thursday, September 16, 2010 |
APPL NO | 12/884001 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) Original (OR) Class H01J 37/228 (20130101) H01J 37/285 (20130101) H01J 2237/0432 (20130101) H01J 2237/2004 (20130101) H01J 2237/2065 (20130101) H01J 2237/2611 (20130101) H01J 2237/2803 (20130101) H01J 2237/20207 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841650 | Raza |
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FUNDED BY |
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APPLICANT(S) | Hassan Raza (Iowa City, Iowa) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Hassan Raza (Iowa City, Iowa) |
ABSTRACT | An electronic structure modulation transistor having two gates separated from a channel by corresponding dielectric layers, wherein the channel is formed of a material having an electronic structure that is modified by an electric field across the channel. |
FILED | Tuesday, February 23, 2010 |
APPL NO | 12/711007 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0673 (20130101) H01L 29/775 (20130101) Original (OR) Class H01L 29/778 (20130101) H01L 29/1606 (20130101) H01L 51/0558 (20130101) H01L 51/0595 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/734 (20130101) Y10S 977/762 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842291 | Turner et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew D. Turner (Seattle, Washington); Jens H. Gundlach (Seattle, Washington); Charles A. Hagedorn (Seattle, Washington); Stephan Schlamminger (Rockville, Maryland) |
ASSIGNEE(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | Matthew D. Turner (Seattle, Washington); Jens H. Gundlach (Seattle, Washington); Charles A. Hagedorn (Seattle, Washington); Stephan Schlamminger (Rockville, Maryland) |
ABSTRACT | Systems and method are disclosed for measuring small angular deflections of a target using weak value amplification. A system includes a beam source, a beam splitter, a target reflecting surface, a photodetector, and a processor. The beam source generates an input beam that is split into first and second beams by the beam splitter. The first and second beams are propagated to the target reflecting surface, at least partially superimposed at the target reflecting surface, and incident to the target reflecting surface normal to the target reflecting surface. The first beam is reflected an additional even number of times during propagation to the photodetector. The second beam is reflected an additional odd number of times during propagation to the photodetector. The first and second beams interfere at the photodetector so as to produce interference patterns. The interference patterns are interpreted to measure angular deflections of the target reflecting surface. |
FILED | Wednesday, March 21, 2012 |
APPL NO | 13/426309 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02032 (20130101) G01B 9/02057 (20130101) G01B 2290/70 (20130101) Optical Elements, Systems, or Apparatus G02B 27/10 (20130101) G02B 27/62 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842688 | Vahdat et al. |
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FUNDED BY |
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APPLICANT(S) | Amin Vahdat (Poway, California); Nathan Farrington (La Jolla, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Amin Vahdat (Poway, California); Nathan Farrington (La Jolla, California) |
ABSTRACT | High speed switching networks can be created with a minimum of cabling complexity using pod switches that are connected to a core switch array. Each pod switch can include line cards arranged in parallel connecting on one side of a midplane circuit board that is orthogonal to the line cards and uplink cards also arranged in parallel connecting on an opposite side of the midplane circuit board. The uplink cards are orthogonal to both the midplane circuit board and to the line cards. Each line card provides links to computing nodes. The uplink cards connect to the core switch array. A simplified novel Ethernet extension protocol can be used in conjunction with the described hardware. Systems, methods, techniques, and articles of manufacture are also described. |
FILED | Wednesday, January 20, 2010 |
APPL NO | 13/143994 |
ART UNIT | 2469 — Multiplex and VoIP |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 49/40 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843363 | Birnbaum et al. |
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FUNDED BY |
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APPLICANT(S) | Narrative Science Inc. (Chicago, Illinois) |
ASSIGNEE(S) | Narrative Science Inc. (Chicago, Illinois) |
INVENTOR(S) | Lawrence A. Birnbaum (Evanston, Illinois); Kristian J. Hammond (Chicago, Illinois); Nicholas D. Allen (Chicago, Illinois); John R. Templon (Chicago, Illinois) |
ABSTRACT | A system and method for automatically generating a narrative story receives data and information pertaining to a domain event. The received data and information and/or one or more derived features are then used to identify a plurality of angles for the narrative story. The plurality of angles is then filtered, for example through use of parameters that specify a focus for the narrative story, length of the narrative story, etc. Points associated with the filtered plurality of angles are then assembled and the narrative story is rendered using the filtered plurality of angles and the assembled points. |
FILED | Thursday, January 10, 2013 |
APPL NO | 13/738560 |
ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
CURRENT CPC | Electric Digital Data Processing G06F 17/28 (20130101) Original (OR) Class G06F 17/2881 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843490 | Gazen et al. |
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FUNDED BY |
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APPLICANT(S) | Bora C. Gazen (Huntington Beach, California); Steven N. Minton (El Segundo, California) |
ASSIGNEE(S) | Connotate, Inc. (New Brunswick, New Jersey) |
INVENTOR(S) | Bora C. Gazen (Huntington Beach, California); Steven N. Minton (El Segundo, California) |
ABSTRACT | In accordance with an embodiment, data may be automatically extracted from semi-structured web sites. Unsupervised learning may be used to analyze web sites and discover their structure. One method utilizes a set of heterogeneous “experts,” each expert being capable of identifying certain types of generic structure. Each expert represents its discoveries as “hints.” Based on these hints, the system may cluster the pages and text segments and identify semi-structured data that can be extracted. To identify a good clustering, a probabilistic model of the hint-generation process may be used. |
FILED | Tuesday, July 26, 2011 |
APPL NO | 13/191369 |
ART UNIT | 2169 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 17/3071 (20130101) Original (OR) Class G06F 17/30861 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843932 | Sohi et al. |
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FUNDED BY |
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APPLICANT(S) | Gurindar S. Sohi (Madison, Wisconsin); Srinath Sridharan (Madison, Wisconsin); Gagan Gupta (Fitchburg, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Gurindar S. Sohi (Madison, Wisconsin); Srinath Sridharan (Madison, Wisconsin); Gagan Gupta (Fitchburg, Wisconsin) |
ABSTRACT | Execution of a computer program on a multiprocessor system is monitored to detect possible excess parallelism causing resource contention and the like and, in response, to controllably limit the number of processors applied to parallelize program components. |
FILED | Wednesday, January 12, 2011 |
APPL NO | 13/005333 |
ART UNIT | 2196 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/5066 (20130101) Original (OR) Class G06F 2209/508 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08844032 | Saidi et al. |
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FUNDED BY |
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APPLICANT(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ABSTRACT | A method and system for application-based monitoring and enforcement of security, privacy, performance and/or other policies on a mobile device includes incorporating monitoring and policy enforcement code into a previously un-monitored software application package that is installable on a mobile device, and executing the monitoring and policy enforcement code during normal use of the software application by a user of the mobile device. |
FILED | Friday, March 02, 2012 |
APPL NO | 13/411200 |
ART UNIT | 2496 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1408 (20130101) H04L 63/1416 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08844036 | Saidi et al. |
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FUNDED BY |
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APPLICANT(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Hassen Saidi (Menlo Park, California); Rubin Xu (Cambridge, United Kingdom) |
ABSTRACT | A method and system for application-based monitoring and enforcement of security, privacy, performance and/or other policies on a mobile device includes incorporating monitoring and policy enforcement code into a previously un-monitored software application package that is installable on a mobile device, and executing the monitoring and policy enforcement code during normal use of the software application by a user of the mobile device. |
FILED | Friday, March 02, 2012 |
APPL NO | 13/411072 |
ART UNIT | 2496 — Cryptography and Security |
CURRENT CPC | Information security 726/23 |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 08839738 | Paxson |
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FUNDED BY |
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APPLICANT(S) | Daniel E. Paxson (Parma Heights, Ohio) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Daniel E. Paxson (Parma Heights, Ohio) |
ABSTRACT | An apparatus and method for thermal spraying a metal coating on a substrate is accomplished with a modified pulsejet and optionally an ejector to assist in preventing oxidation. Metal such as Aluminum or Magnesium may be used. A pulsejet is first initiated by applying fuel, air, and a spark. Metal is inserted continuously in a high volume of metal into a combustion chamber of the pulsejet. The combustion is thereafter controlled resonantly at high frequency and the metal is heated to a molten state. The metal is then transported from the combustion chamber into a tailpipe of said pulsejet and is expelled therefrom at high velocity and deposited on a target substrate. |
FILED | Tuesday, July 13, 2010 |
APPL NO | 12/835345 |
ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/203 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/08 (20130101) C23C 4/124 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08839996 | Parazynski et al. |
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FUNDED BY |
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APPLICANT(S) | Scott E. Parazynski (Houston, Texas); Grant C. Bue (Houston, Texas); Mark E. Schaefbauer (League City, Texas); Kase C. Urban (League City, Texas) |
ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Scott E. Parazynski (Houston, Texas); Grant C. Bue (Houston, Texas); Mark E. Schaefbauer (League City, Texas); Kase C. Urban (League City, Texas) |
ABSTRACT | An apparatus and method for storing and delivering fluid to a person comprises, in at least one specific embodiment, a fluid reservoir having an internal volume therein with an opening disposed through a first wall or a second wall of the fluid reservoir and located toward a first end of the fluid reservoir. A first portion of a tube can be exterior to the fluid reservoir and a second portion of the tube can be disposed through the opening and within the internal volume. At least one insulation layer can be disposed about the exterior of the first wall of the fluid reservoir. The second wall of the fluid reservoir can be configured for transferring heat from or to the internal volume or from the person. At least one baffle is disposed within the internal volume and connected to the first wall and the second wall of the fluid reservoir. |
FILED | Wednesday, November 04, 2009 |
APPL NO | 12/612171 |
ART UNIT | 3782 — Fluid Handling and Dispensing |
CURRENT CPC | Travelling or Camp Equipment: Sacks or Packs Carried on the Body A45F 3/04 (20130101) A45F 3/16 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
08841406 — Branched rod-coil polyimide—poly( alkylene oxide) copolymers and electrolyte compositions
US 08841406 | Meador et al. |
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FUNDED BY |
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APPLICANT(S) | Maryann B. Meador (Strongsville, Ohio); Dean M. Tigelaar (Seven Hills, Ohio) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Maryann B. Meador (Strongsville, Ohio); Dean M. Tigelaar (Seven Hills, Ohio) |
ABSTRACT | Crosslinked polyimide-poly(alkylene oxide) copolymers capable of holding large volumes of liquid while maintaining good dimensional stability. Copolymers are derived at ambient temperatures from amine endcapped amic-acid oligomers subsequently imidized in solution at increased temperatures, followed by reaction with trifunctional compounds in the presence of various additives. Films of these copolymers hold over four times their weight at room temperature of liquids such as ionic liquids (RTIL) and/or carbonate solvents. These rod-coil polyimide copolymers are used to prepare polymeric electrolytes by adding to the copolymers various amounts of compounds such as ionic liquids (RTIL), lithium trifluoromethane-sulfonimide (LiTFSi) or other lithium salts, and alumina. |
FILED | Monday, December 22, 2008 |
APPL NO | 12/317232 |
ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3326 (20130101) C08G 65/33306 (20130101) Original (OR) Class C08G 65/33355 (20130101) C08G 2650/50 (20130101) Compositions of Macromolecular Compounds C08L 2205/05 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/137 (20130101) H01M 4/624 (20130101) H01M 4/626 (20130101) H01M 6/181 (20130101) H01M 6/188 (20130101) H01M 10/0565 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841698 | Neudeck |
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FUNDED BY |
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APPLICANT(S) | Philip G. Neudeck (Ohmsted Falls, Ohio) |
ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
INVENTOR(S) | Philip G. Neudeck (Ohmsted Falls, Ohio) |
ABSTRACT | A method is disclosed that provides a self-aligned nitrogen-implant particularly suited for a Junction Field Effect Transistor (JFET) semiconductor device preferably comprised of a silicon carbide (SiC). This self-aligned nitrogen-implant allows for the realization of durable and stable electrical functionality of high temperature transistors such as JFETs. The method implements the self-aligned nitrogen-implant having predetermined dimensions, at a particular step in the fabrication process, so that the SiC junction field effect transistors are capable of being electrically operating continuously at 500° C. for over 10,000 hours in an air ambient with less than a 10% change in operational transistor parameters. |
FILED | Friday, April 01, 2011 |
APPL NO | 13/078510 |
ART UNIT | 2897 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0465 (20130101) H01L 21/0475 (20130101) H01L 29/808 (20130101) Original (OR) Class H01L 29/0843 (20130101) H01L 29/1602 (20130101) H01L 29/1608 (20130101) H01L 29/2003 (20130101) H01L 29/66068 (20130101) H01L 29/66901 (20130101) H01L 29/66916 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842291 | Turner et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew D. Turner (Seattle, Washington); Jens H. Gundlach (Seattle, Washington); Charles A. Hagedorn (Seattle, Washington); Stephan Schlamminger (Rockville, Maryland) |
ASSIGNEE(S) | University of Washington Through Its Center for Commercialization (Seattle, Washington) |
INVENTOR(S) | Matthew D. Turner (Seattle, Washington); Jens H. Gundlach (Seattle, Washington); Charles A. Hagedorn (Seattle, Washington); Stephan Schlamminger (Rockville, Maryland) |
ABSTRACT | Systems and method are disclosed for measuring small angular deflections of a target using weak value amplification. A system includes a beam source, a beam splitter, a target reflecting surface, a photodetector, and a processor. The beam source generates an input beam that is split into first and second beams by the beam splitter. The first and second beams are propagated to the target reflecting surface, at least partially superimposed at the target reflecting surface, and incident to the target reflecting surface normal to the target reflecting surface. The first beam is reflected an additional even number of times during propagation to the photodetector. The second beam is reflected an additional odd number of times during propagation to the photodetector. The first and second beams interfere at the photodetector so as to produce interference patterns. The interference patterns are interpreted to measure angular deflections of the target reflecting surface. |
FILED | Wednesday, March 21, 2012 |
APPL NO | 13/426309 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02032 (20130101) G01B 9/02057 (20130101) G01B 2290/70 (20130101) Optical Elements, Systems, or Apparatus G02B 27/10 (20130101) G02B 27/62 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
08842761 — Methodology and method and apparatus for signaling with capacity optimized constellations
US 08842761 | Barsoum et al. |
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FUNDED BY |
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APPLICANT(S) | Maged F. Barsoum (Saratoga, California); Christopher R. Jones (Pacific Palisades, California) |
ASSIGNEE(S) | Constellation Designs, Inc. (Pacific Palisades, California) |
INVENTOR(S) | Maged F. Barsoum (Saratoga, California); Christopher R. Jones (Pacific Palisades, California) |
ABSTRACT | Communication systems are described that use geometrically shaped constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. In several embodiments, the geometrically shaped is optimized based upon a capacity measure such as parallel decoding capacity or joint capacity. In many embodiments, a capacity optimized geometrically shaped constellation can be used to replace a conventional constellation as part of a firmware upgrade to transmitters and receivers within a communication system. In a number of embodiments, the geometrically shaped constellation is optimized for an Additive White Gaussian Noise channel or a fading channel. In numerous embodiments, the communication uses adaptive rate encoding and the location of points within the geometrically shaped constellation changes as the code rate changes. |
FILED | Friday, September 14, 2012 |
APPL NO | 13/618630 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Transmission H04B 15/00 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 08841434 | Thilmony et al. |
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FUNDED BY |
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APPLICANT(S) | Roger L Thilmony (El Cerrito, California); Mara E Guttman (Kensington, California); James G Thomson (El Cerrito, California) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Roger L Thilmony (El Cerrito, California); Mara E Guttman (Kensington, California); James G Thomson (El Cerrito, California) |
ABSTRACT | The present invention relates to isolated rice LP2 promoter sequences and uses thereof. |
FILED | Monday, September 27, 2010 |
APPL NO | 12/890974 |
ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8237 (20130101) C12N 15/8239 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08841470 | Biswas et al. |
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FUNDED BY |
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APPLICANT(S) | Atanu Biswas (Peoria, Illinois); Kenneth M. Doll (Peoria, Illinois); Huai Nan Cheng (Metairie, Louisiana); Brajendra K. Sharma (Savoy, Illinois) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); The Penn State Research Foundation (University Park, Pennsylvania) |
INVENTOR(S) | Atanu Biswas (Peoria, Illinois); Kenneth M. Doll (Peoria, Illinois); Huai Nan Cheng (Metairie, Louisiana); Brajendra K. Sharma (Savoy, Illinois) |
ABSTRACT | Chemically-modified fatty acids are prepared by reacting epoxidized fatty acids, their esters or triglyceride oils with amines of cyclic or aromatic hydrocarbons. The fatty acid derivatives produced are of the formula: wherein R is an H, branched or straight chain alkyl or alkenyl group, aromatic-containing group, glycerol, or glyceride, R″ is a C3 to C29 aliphatic chain comprising one or more of the derivatized methylene groups of the formula: wherein R1 and R2 are independently selected from the group consisting of H, cyclic hydrocarbons, substituted cyclic hydrocarbons, and aryl groups, with the proviso that only one of said R1 and R2 may be H. These fatty acid derivatives have utility as antiwear/antifriction additives for industrial oils and automotive applications. |
FILED | Wednesday, August 24, 2011 |
APPL NO | 13/216841 |
ART UNIT | 1672 — Organic Chemistry |
CURRENT CPC | Organic compounds 554/114 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 08839807 | Kent et al. |
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FUNDED BY |
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APPLICANT(S) | Steven R. Kent (Downey, California); James S. Wells (Fountain Valley, California); John E. Kuhn (Huntington Beach, California) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Steven R. Kent (Downey, California); James S. Wells (Fountain Valley, California); John E. Kuhn (Huntington Beach, California) |
ABSTRACT | A rapid response self-closing pressure equalization vent employs a frame supported in a compartment divider and a movable vent portion having a periphery sealingly engaging the frame in a closed position. Multiple resilient extension elements are attached to the frame and engage the movable vent portion for even displacement around a periphery of the movable vent portion relative to the frame to an open position responsive to a pressure differential on the movable vent portion. The resilient extension elements retract upon equalization of the pressure differential to reseat the movable vent portion in the frame. |
FILED | Friday, October 08, 2010 |
APPL NO | 12/901325 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/023 (20130101) Original (OR) Class F16K 17/0493 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842881 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | Dashan Gao (Rexford, New York); Ting Yu (Albany, New York); Li Guan (Clifton Park, New York); Yi Yao (Rexford, New York); Kedar Anil Patwardhan (Latham, New York); Peter Henry Tu (Niskayuna, New York) |
ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
INVENTOR(S) | Dashan Gao (Rexford, New York); Ting Yu (Albany, New York); Li Guan (Clifton Park, New York); Yi Yao (Rexford, New York); Kedar Anil Patwardhan (Latham, New York); Peter Henry Tu (Niskayuna, New York) |
ABSTRACT | A method for detecting and tracking a target includes detecting the target using a plurality of feature cues, fusing the plurality of feature cues to form a set of target hypotheses, tracking the target based on the set of target hypotheses and a scene context analysis, and updating the tracking of the target based on a target motion model. |
FILED | Thursday, April 26, 2012 |
APPL NO | 13/456399 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image analysis 382/103 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
US 08842289 | Montgomery et al. |
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FUNDED BY |
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APPLICANT(S) | Harris Corporation (Melbourne, Florida) |
ASSIGNEE(S) | Harris Corporation (Melbourne, Florida) |
INVENTOR(S) | Robert M. Montgomery (Indialantic, Florida); Randy L. Carmean (Malabar, Florida); Charles Franklin Middleton, IV (Rockledge, Florida); James G. Tonti (Palm Bay, Florida) |
ABSTRACT | A biological sensing apparatus comprises an excitation source configured to induce waves in a biological target, and an optical waveguide interferometer configured to sense the induced waves in the biological target. The optical waveguide interferometer comprises a probe segment having a probe segment end, and an adjustable coupler configured to permit setting a gap between the probe segment end and the biological target. A controller is coupled to the adjustable coupler and configured to set the gap between the probe segment end and the biological target. |
FILED | Monday, January 13, 2014 |
APPL NO | 14/153650 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0205 (20130101) G01B 9/02068 (20130101) G01B 11/0666 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/2418 (20130101) G01N 2291/02475 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08842290 | Montgomery et al. |
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FUNDED BY |
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APPLICANT(S) | Harris Corporation (Melbourne, Florida) |
ASSIGNEE(S) | Harris Corporation (Melbourne, Florida) |
INVENTOR(S) | Robert M. Montgomery (Indialantic, Florida); Randy L. Carmean (Malabar, Florida); Charles Franklin Middleton, IV (Rockledge, Florida); James G. Tonti (Palm Bay, Florida) |
ABSTRACT | A sensing apparatus comprises an excitation source configured to induce waves in a target, and a fiber optic interferometer configured to sense the induced waves in the target. The fiber optic interferometer comprises a probe segment having a probe segment end, and an adjustable coupler configured to permit setting a gap between the probe segment end and the target. A controller is coupled to the adjustable coupler and configured to set the gap between the probe segment end and the target. |
FILED | Tuesday, December 17, 2013 |
APPL NO | 14/108476 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0084 (20130101) A61B 5/1075 (20130101) A61B 5/6886 (20130101) A61B 2562/223 (20130101) A61B 2562/0233 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0205 (20130101) G01B 9/02049 (20130101) Original (OR) Class G01B 9/02068 (20130101) G01B 11/0666 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/043 (20130101) G01N 29/2418 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 08842722 | Dickson et al. |
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FUNDED BY |
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APPLICANT(S) | Timothy O. Dickson (Danbury, Connecticut); Rui Yan Matthew Loh (Pasadena, California) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Timothy O. Dickson (Danbury, Connecticut); Rui Yan Matthew Loh (Pasadena, California) |
ABSTRACT | Equalization techniques are provided for high-speed data communications and, more specifically, DFE (decision feedback equalizer) circuits and methods are provided which implement a high-order continuous time filter in a DFE feedback path to emulate structured elements of a channel response. |
FILED | Wednesday, August 22, 2012 |
APPL NO | 13/591403 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Pulse or digital communications 375/233 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843904 | Andrade et al. |
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FUNDED BY |
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APPLICANT(S) | Henrique Andrade (Croton-on-Hudson, New York); Judah M. Diament (Bergenfield, New Jersey); Bugra Gedik (White Plains, New York); Anton V. Riabov (Ossining, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Henrique Andrade (Croton-on-Hudson, New York); Judah M. Diament (Bergenfield, New Jersey); Bugra Gedik (White Plains, New York); Anton V. Riabov (Ossining, New York) |
ABSTRACT | Architecture-dependent assets are automatically built and retargeted. An asset originally built for one architecture is downloaded and automatically retargeted on another architecture. This automatically retargeting may be performed on demand, at runtime. |
FILED | Tuesday, January 26, 2010 |
APPL NO | 12/693554 |
ART UNIT | 2192 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 8/60 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
US 08841460 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | State of Oregon, acting by and through the State Board of Higher Education on behalf of University of Oregon (Eugene, Oregon) |
ASSIGNEE(S) | State of Oregon Acting by and Through the State Board of Higher Education on Behalf of the University of Oregon (Igene, Oregon) |
INVENTOR(S) | Darren W. Johnson (Eugene, Oregon); Calden Carroll (Eugene, Oregon); Michael M. Haley (Eugene, Oregon); Jeff Engle (Eugene, Oregon) |
ABSTRACT | A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl. |
FILED | Friday, December 14, 2012 |
APPL NO | 13/715979 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Organic compounds 546/337 |
VIEW PATENT | @ USPTO: Full Text PDF |
US 08843315 | Barbeau et al. |
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FUNDED BY |
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APPLICANT(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida); Narin Persad (Hollywood, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida); Narin Persad (Hollywood, Florida) |
ABSTRACT | This present invention is a spatial data processing system and method that allows the automatic, rapid, scalable analysis and transformation of large amounts of travel behavior data (e.g., tracking data points) into individual “points-of-interest” and discrete trips stored in a spatial database. Each trip has a point-of-interest as a starting and ending location, and contains multiple positions (e.g. latitude and longitudes) which define the travel path of the user/device during that time period. |
FILED | Thursday, June 28, 2012 |
APPL NO | 13/536115 |
ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 08843315 | Barbeau et al. |
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FUNDED BY |
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APPLICANT(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida); Narin Persad (Hollywood, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Sean J. Barbeau (Tampa, Florida); Philip L. Winters (Tampa, Florida); Rafael Perez (Temple Terrace, Florida); Miguel Labrador (Tampa, Florida); Nevine Georggi (Valrico, Florida); Narin Persad (Hollywood, Florida) |
ABSTRACT | This present invention is a spatial data processing system and method that allows the automatic, rapid, scalable analysis and transformation of large amounts of travel behavior data (e.g., tracking data points) into individual “points-of-interest” and discrete trips stored in a spatial database. Each trip has a point-of-interest as a starting and ending location, and contains multiple positions (e.g. latitude and longitudes) which define the travel path of the user/device during that time period. |
FILED | Thursday, June 28, 2012 |
APPL NO | 13/536115 |
ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/486 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 08841276 | Arbiser |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia); The United States of America Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Jack L. Arbiser (Atlanta, Georgia) |
ABSTRACT | Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are fulvene and/or fulvalene analogs. The compounds and compositions can be used to treat and/or prevent a wide variety of cancers, including drug resistant cancers, as well as numerous inflammatory, degenerative and vascular diseases, including various ocular diseases. Representative fulvene and/or fulvalene analogs include fulvene and fulvalene analogs of various dyes, hormones, sugars, peptides, oligonucleotides, amino acids, nucleotides, nucleosides, and polyols. The compounds are believed to function, at least, by inhibiting Nox or ROS. In some embodiments, the Nox is one that is selectively expressed in cancer cells over normal cells, or one that is expressed in higher amounts in cancer cells over normal cells. Thus, the compounds are novel therapeutic agents for a variety of cancers and other diseases. |
FILED | Tuesday, August 20, 2013 |
APPL NO | 13/970639 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/015 (20130101) A61K 31/045 (20130101) A61K 31/167 (20130101) A61K 31/341 (20130101) A61K 31/357 (20130101) A61K 31/403 (20130101) A61K 31/444 (20130101) A61K 31/573 (20130101) A61K 31/4164 (20130101) A61K 31/5375 (20130101) Acyclic or Carbocyclic Compounds C07C 13/28 (20130101) C07C 13/40 (20130101) C07C 13/58 (20130101) C07C 13/66 (20130101) C07C 13/465 (20130101) C07C 25/18 (20130101) C07C 35/32 (20130101) C07C 39/23 (20130101) C07C 43/23 (20130101) C07C 43/215 (20130101) C07C 69/608 (20130101) C07C 211/50 (20130101) C07C 215/46 (20130101) C07C 233/44 (20130101) C07C 237/26 (20130101) C07C 251/28 (20130101) C07C 275/64 (20130101) C07C 2101/10 (20130101) C07C 2102/08 (20130101) C07C 2102/42 (20130101) C07C 2103/24 (20130101) C07C 2103/40 (20130101) C07C 2103/46 (20130101) Heterocyclic Compounds C07D 209/14 (20130101) Original (OR) Class C07D 209/82 (20130101) C07D 209/86 (20130101) C07D 213/53 (20130101) C07D 233/58 (20130101) C07D 233/68 (20130101) C07D 261/08 (20130101) C07D 277/40 (20130101) C07D 295/03 (20130101) C07D 295/135 (20130101) C07D 307/58 (20130101) C07D 309/38 (20130101) C07D 311/58 (20130101) C07D 311/60 (20130101) C07D 311/82 (20130101) C07D 407/04 (20130101) C07D 471/10 (20130101) C07D 473/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 08840706 | Srinivasachar |
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FUNDED BY |
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APPLICANT(S) | Srivats Srinivasachar (Sturbridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Srivats Srinivasachar (Sturbridge, Massachusetts) |
ABSTRACT | A composition, process and system for capturing carbon dioxide from a combustion gas stream. The composition has a particulate porous support medium that has a high volume of pores, an alkaline component distributed within the pores and on the surface of the support medium, and water adsorbed on the alkaline component, wherein the proportion of water in the composition is between about 5% and about 35% by weight of the composition. The process and system contemplates contacting the sorbent and the flowing gas stream together at a temperature and for a time such that some water remains adsorbed in the alkaline component when the contact of the sorbent with the flowing gas ceases. |
FILED | Wednesday, May 23, 2012 |
APPL NO | 13/478184 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Gas separation: Processes 095/139 |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 08841084 | Liang et al. |
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FUNDED BY |
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APPLICANT(S) | Bruce T. Liang (Avon, Connecticut); Heiko Schmitt (Farmington, Connecticut); Michael Azrin (Southington, Connecticut); Christopher C. Pickett (Farmington, Connecticut); Allan S. Jaffe (Rochester, Minnesota) |
ASSIGNEE(S) | The University of Connecticut (Farmington, Connecticut); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Bruce T. Liang (Avon, Connecticut); Heiko Schmitt (Farmington, Connecticut); Michael Azrin (Southington, Connecticut); Christopher C. Pickett (Farmington, Connecticut); Allan S. Jaffe (Rochester, Minnesota) |
ABSTRACT | Disclosed herein are methods of detecting and/or prognosing myocardial infarction by detecting a proteolytic fragment of caspase-3 such as the p17 fragment or the p12 fragment. The myocardial infarction can be STEMI or NSTEMI. |
FILED | Thursday, May 12, 2011 |
APPL NO | 13/697555 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2333/96469 (20130101) G01N 2510/00 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/324 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 23, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20140923.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page