FedInvent™ Patents
Patent Details for Tuesday, November 18, 2014
This page was updated on Monday, March 27, 2023 at 04:07 AM GMT
Department of Health and Human Services (HHS)
| US 08887552 | Madsen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ernest L. Madsen (Madison, Wisconsin); Gary R. Frank (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ernest L. Madsen (Madison, Wisconsin); Gary R. Frank (Madison, Wisconsin) |
| ABSTRACT | A phantom used in quality assurance and performance tests and/or in pre-purchase testing of ultrasound scanners is provided. The phantom includes a container, a boundary formed within the container, and a curved scanning surface. The container includes a top surface, a bottom surface opposite the top surface, and a wall mounted between the top surface and the bottom surface to form the container. The boundary is configured to hold a tissue mimicking material. The curved scanning surface is formed in the top surface in a direction towards an interior of the container. The curved scanning surface is shaped to support translation perpendicular to an image plane of an application end of an ultrasound transducer along at least a portion of an axis extending between a first location on the curved scanning surface and a second location on the curved scanning surface. |
| FILED | Thursday, December 01, 2011 |
| APPL NO | 13/308662 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/1.860 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887721 | Zapol et al. |
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| FUNDED BY |
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| APPLICANT(S) | Warren M. Zapol (Cambridge, Massachusetts); Binglan Yu (Arlington, Massachusetts); Fumito Ichinose (Brookline, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Warren M. Zapol (Cambridge, Massachusetts); Binglan Yu (Arlington, Massachusetts); Fumito Ichinose (Brookline, Massachusetts) |
| ABSTRACT | Compositions and methods for preventing or reducing vasoconstriction in a mammal following administration of an artificial oxygen carrier (e.g., a hemoglobin-based oxygen carrier) are disclosed. The methods include administering to a mammal a composition containing an artificial oxygen carrier in combination with one or more of a nitric oxide-releasing compound, a therapeutic gas containing gaseous nitric oxide, a phosphodiesterase inhibitor, and/or a soluble guanylate cyclase sensitizer. |
| FILED | Tuesday, November 06, 2007 |
| APPL NO | 12/513624 |
| ART UNIT | 3778 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Original (OR) Class A61K 33/00 (20130101) A61K 38/42 (20130101) A61K 38/42 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/12 (20130101) A61M 16/208 (20130101) A61M 2016/003 (20130101) A61M 2016/0039 (20130101) A61M 2016/1035 (20130101) A61M 2202/0275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888285 | Sharma et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Robin Sharma (Rochester, New York); Yusufu N. Sulai (Milwaukee, Wisconsin) |
| ABSTRACT | A tunable, achromatizing optical system for use with a broadband imaging modality system for imaging objects having a range of longitudinal chromatic aberration (LCA) values. The optical system includes an achromatizing component and a parfocal component, for example, a zoom system. A method for tuning the wavefront curvature of different chromatic components of objects having a range of longitudinal chromatic aberration (LCA) values when imaged by a broadband imaging modality system includes the steps of providing a broadband imaging modality system having an entrance pupil, for imaging an object having longitudinal chromatic aberration; providing a tunable, achromatizing optical system; and varying the focal length of the parfocal component while maintaining a conjugate relationship between the achromatizing component and the entrance pupil of the broadband imaging modality system. |
| FILED | Wednesday, October 16, 2013 |
| APPL NO | 14/054962 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888712 | Turner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees Of Southern Illinois University (Springfield, Illinois) |
| ASSIGNEE(S) | Board of Trustees of Southern Illinois University (Springfield, Illinois) |
| INVENTOR(S) | Jeremy Turner (Jacksonville, Illinois); James Michael Kinder (Julian, California) |
| ABSTRACT | Objectively identifying an acoustic characteristic of tinnitus of a subject. The subject is exposed to a sound pattern having a background acoustic signal preceding an audible silence. The background acoustic signal has a selected acoustic characteristic. An electrical response of the subject's central nervous system to the exposure to the sound pattern is measured. The measured electrical response has a first portion representing the electrical response of the subject's central nervous system to the background acoustic signal, and a second portion representing the electrical response of the subject's central nervous system to the audible silence in the sound pattern. The first portion of the measured electrical response is compared to the second portion of the measured electrical response and a determination is made as to whether the subject has tinnitus with an acoustic characteristic similar to the selected acoustic characteristic based on the comparison. |
| FILED | Monday, January 14, 2013 |
| APPL NO | 13/741085 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/121 (20130101) A61B 5/128 (20130101) Original (OR) Class A61B 5/04001 (20130101) A61B 5/04845 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888902 | Galbraith et al. |
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| FUNDED BY |
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| APPLICANT(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
| ASSIGNEE(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
| INVENTOR(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
| ABSTRACT | Lightweight, small, portable devices and methods are disclosed that provide oxygen-enriched air using an ultra rapid adsorption cycle based on advanced molecular sieve materials. |
| FILED | Wednesday, August 15, 2012 |
| APPL NO | 13/586223 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/10 (20130101) Separation B01D 53/053 (20130101) Original (OR) Class B01D 53/0446 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2256/12 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889124 | Hadeiba et al. |
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| FUNDED BY |
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| APPLICANT(S) | Husein Hadeiba (Daly City, California); Eugene C. Butcher (Portola Valley, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Husein Hadeiba (Daly City, California); Eugene C. Butcher (Portola Valley, California) |
| ABSTRACT | Tolerogenic populations of dendritic cells are provided, where the dendritic cells are characterized by expression of select tissue-specific homing receptors including the chemokine receptors CCR9; or CMKLR1; or the integrin CD103. The dendritic cells may be conventional/myeloid or plasmacytoid dendritic cells. The cells may be isolated from lymphoid tissue, from blood, or from in vitro culture, e.g. bone marrow culture, etc. Methods are provided for their identification, isolation and targeting in immunotherapeutic interventions in suppressing inflammatory disorders including autoimmunity, transplantation responses and allergic diseases. In some embodiments dendritic cell populations are fixed to render them immunosuppressive, thus allowing the cells to be typed and banked for future use. |
| FILED | Thursday, September 24, 2009 |
| APPL NO | 12/566454 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) Original (OR) Class A61K 2035/122 (20130101) A61K 2039/5154 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889127 | Muro Galindo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Silvia Muro Galindo (Madrid, Spain); Vladimir R. Muzykantov (Warminster, Pennsylvania); Edward Howard Schuchman (Haworth, New Jersey) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Silvia Muro Galindo (Madrid, Spain); Vladimir R. Muzykantov (Warminster, Pennsylvania); Edward Howard Schuchman (Haworth, New Jersey) |
| ABSTRACT | The present invention relates to compositions and methods for delivering lysosomal proteins. The compositions and methods described herein permit the targeted delivery of exogenous lysosomal proteins to cell surface proteins that allow their internalization via non-clathrin pathways. The present invention further relates to the use of the compositions and methods for enzyme replacement therapy of lysosomal storage diseases. Nucleic acids, recombinant cells and kits useful for making and using the compositions of the invention are also provided. |
| FILED | Friday, July 01, 2005 |
| APPL NO | 11/631248 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/48561 (20130101) Peptides C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889138 | Acton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Paul Acton (Newbury Park, California); Zhiqiang An (Ambler, Pennsylvania); Andrew J. Bett (Lansdale, Pennsylvania); Robert Breese (Quakertown, Pennsylvania); Elizabeth Chen Dodson (Souderton, Pennsylvania); Gene Kinney (Collegeville, Pennsylvania); William L Klein (Winetka, Illinois); Mary P. Lambert (Glenview, Illinois); Xiaoping Liang (Collegeville, Pennsylvania); Paul Shughrue (West Chester, Pennsylvania); William R. Strohl (Bridgewater, New Jersey); Kirsten Viola (Chicago, Illinois); Lei Chang (Westmont, Illinois) |
| ASSIGNEE(S) | Merck Sharp and Dohme Corp. (Rahway, New Jersey); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Paul Acton (Newbury Park, California); Zhiqiang An (Ambler, Pennsylvania); Andrew J. Bett (Lansdale, Pennsylvania); Robert Breese (Quakertown, Pennsylvania); Elizabeth Chen Dodson (Souderton, Pennsylvania); Gene Kinney (Collegeville, Pennsylvania); William L Klein (Winetka, Illinois); Mary P. Lambert (Glenview, Illinois); Xiaoping Liang (Collegeville, Pennsylvania); Paul Shughrue (West Chester, Pennsylvania); William R. Strohl (Bridgewater, New Jersey); Kirsten Viola (Chicago, Illinois); Lei Chang (Westmont, Illinois) |
| ABSTRACT | The present invention relates to antibodies that differentially recognize multi-dimensional conformations of Aβ-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can distinguish between Alzheimer's Disease and control human brain extracts and are useful in methods of detecting ADDLs and diagnosing Alzheimer's Disease. The present antibodies also block binding of ADDLs to neurons, assembly of ADDLS, and tau phosphorylation and are there useful in methods for the preventing and treating diseases associated with soluble oligomers of amyloid β 1-42. |
| FILED | Monday, October 11, 2010 |
| APPL NO | 12/901738 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/18 (20130101) C07K 2316/96 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2333/4709 (20130101) G01N 2800/2814 (20130101) G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889149 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fu-shin X. Yu (Troy, Michigan); Ashok Kumar (Detroit, Michigan); Jing Zhang (Northville, Michigan); Linda D. Hazlett (Grosse Point, Michigan); Jia Yin (Warren, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Fu-shin X. Yu (Troy, Michigan); Ashok Kumar (Detroit, Michigan); Jing Zhang (Northville, Michigan); Linda D. Hazlett (Grosse Point, Michigan); Jia Yin (Warren, Michigan) |
| ABSTRACT | The disclosure describes use of flagellin polypeptides to induce tolerance to gram negative bacteria, such as Pseudomonas aeruginosa, in order to alleviate the effects of the inflammatory response to bacterial infection in a patient. Also described are methods and compositions for treating and preventing keratitis, cystic fibrosis, asthma, and other diseases and conditions in which inflammation contributes to the pathology and symptoms. |
| FILED | Thursday, February 15, 2007 |
| APPL NO | 12/279671 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889174 | Gibson et al. |
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| FUNDED BY |
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| APPLICANT(S) | John W. Gibson (Springville, Alabama); Arthur J. Tipton (Homewood, Alabama); Richard Holl (Ft. Collins, Colorado); Stacey Meador (Vance, Alabama) |
| ASSIGNEE(S) | Durect Corporation (Cupertino, California) |
| INVENTOR(S) | John W. Gibson (Springville, Alabama); Arthur J. Tipton (Homewood, Alabama); Richard Holl (Ft. Collins, Colorado); Stacey Meador (Vance, Alabama) |
| ABSTRACT | A coaxial implant has been developed using biodegradable polymeric materials. The coaxial implant has a core containing drug, surrounded by a semi-permeable membrane that controls the rate of release of material from the core. The core containing the drug and the polymer membrane(s) can be the same or different polymer. The core acts as a reservoir of drug, which partitions from the core polymer to form a saturated solution of drug at the polymer membrane. |
| FILED | Monday, August 20, 2012 |
| APPL NO | 13/589847 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889196 | Xu |
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| FUNDED BY |
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| APPLICANT(S) | Huakun Xu (Frederick, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Huakun Xu (Frederick, Maryland) |
| ABSTRACT | Described herein are dental composites comprising amorphous calcium phosphate nanoparticles and methods of making and using the same. The dental composites display increased Ca and PO4 release, improved mechanical properties, and improved antibacterial properties. Anti-bacterial agents, such as quaternary ammonium salts or silver-containing nanoparticles may be included in the composites. |
| FILED | Thursday, June 30, 2011 |
| APPL NO | 13/807123 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/0008 (20130101) A61K 6/033 (20130101) A61K 6/0067 (20130101) A61K 6/083 (20130101) A61K 6/083 (20130101) A61K 31/22 (20130101) A61K 33/38 (20130101) Original (OR) Class A61K 47/02 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Compositions of Macromolecular Compounds C08L 33/10 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889348 | Ju |
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| FUNDED BY |
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| APPLICANT(S) | Jingyue Ju (Englewood Cliffs, New Jersey) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey) |
| ABSTRACT | This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides. |
| FILED | Thursday, June 07, 2007 |
| APPL NO | 12/308091 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2525/101 (20130101) C12Q 2565/631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889355 | Kuersten et al. |
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| FUNDED BY |
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| APPLICANT(S) | Applied Biosystems, LLC (Carlsbad, California) |
| ASSIGNEE(S) | Applied Biosystems, LLC (Carlsbad, California) |
| INVENTOR(S) | R. Scott Kuersten (Madison, Wisconsin); Brittan Pasloske (Austin, Texas) |
| ABSTRACT | Ligation-enhanced nucleic acid detection assay embodiments for detection of RNA or DNA are described. The assay embodiments rely on ligation of chimeric oligonucleotide probes to generate a template for amplification and detection. The assay embodiments are substantially independent of the fidelity of a polymerase for copying compromised nucleic acid. Very little background amplification is observed and as few as 1000 copies of target nucleic acid can be detected. Method embodiments are particularly adept for detection of RNA from compromised samples such as formalin-fixed and paraffin-embedded samples. Heavily degraded and cross-linked nucleic acids of compromised samples, in which classic quantitative real time PCR assays typically fail to adequately amplify signal, can be reliably detected and quantified. |
| FILED | Friday, April 26, 2013 |
| APPL NO | 13/871827 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 2525/155 (20130101) C12Q 2525/161 (20130101) C12Q 2561/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889356 | Zhang |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR/Cas system. |
| FILED | Tuesday, February 18, 2014 |
| APPL NO | 14/183471 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/1082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889361 | Chen |
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| FUNDED BY |
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| APPLICANT(S) | Wen-Tien Chen (Stonybrook, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Wen-Tien Chen (Stonybrook, New York) |
| ABSTRACT | The invention is embodied in methods for finding gene expression signatures of circulating melanoma cells, ovarian, breast, colorectal cancer cells, and circulating endothelial progenitor cells, which signatures are effective in distinguishing the circulating cancer cell from normal circulating cells and can also distinguish between different types of circulating cancer cells. |
| FILED | Friday, September 19, 2008 |
| APPL NO | 12/678921 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889365 | Madura et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kiran Madura (Bridgewater, New Jersey); Li Chen (Hills Borough, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Kiran Madura (Bridgewater, New Jersey); Li Chen (Hills Borough, New Jersey) |
| ABSTRACT | The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary proteins thereof, as compared to normal control or benign tissue is indicative of breast cancer. |
| FILED | Monday, August 08, 2011 |
| APPL NO | 13/204947 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57411 (20130101) Original (OR) Class G01N 33/57415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889367 | Attur et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mukundan Attur (Woodside, New York); Steven B. Abramson (Rye, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Mukundan Attur (Woodside, New York); Steven B. Abramson (Rye, New York) |
| ABSTRACT | This disclosure relates to methods and kits for diagnosing osteoarthritis and for determining the progression of osteoarthritis in a subject. |
| FILED | Wednesday, September 14, 2011 |
| APPL NO | 13/232715 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/52 (20130101) G01N 2333/545 (20130101) G01N 2333/964 (20130101) G01N 2333/96494 (20130101) G01N 2800/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889369 | Dertinger |
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| FUNDED BY |
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| APPLICANT(S) | Litron Laboratories, Ltd. (Rochester, New York) |
| ASSIGNEE(S) | Litron Laboratories, Ltd. (Rochester, New York) |
| INVENTOR(S) | Stephen D. Dertinger (Webster, New York) |
| ABSTRACT | A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody having binding specificity for a surface marker for reticulocytes, a second fluorescent labeled antibody having binding specificity for a surface marker for platelets, and a nucleic acid staining dye that stains DNA (micronuclei) in erythrocyte populations. Because the fluorescent emission spectra of the first and second fluorescent labeled antibodies do not substantially overlap with one another or with the emission spectra of the nucleic acid staining dye, upon excitation of the labels and dye it is possible to detect the fluorescent emission and light scatter produced by the erythrocyte populations and platelets, and count the number of cells from one or more erythrocyte populations in said sample. In particular, the use of the second antibody prevents interference by platelet-associated aggregates in the scoring procedures. |
| FILED | Friday, November 08, 2013 |
| APPL NO | 14/075082 |
| ART UNIT | 1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 33/5094 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/968 (20130101) Y10S 435/973 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889377 | Kobilka |
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| FUNDED BY |
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| APPLICANT(S) | ConfometRx, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | ConfometRx, Inc. (Palo Alto, California) |
| INVENTOR(S) | Brian Kobilka (Palo Alto, California) |
| ABSTRACT | Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising, from N-terminus to C-terminus: a) a first portion of a family C G-protein coupled receptor (GPCR), wherein the first portion comprises the TM1, TM2 and TM3, regions of the GPCR; b) a stable, folded protein insertion; and c) a second portion of the GPCR, wherein the second portion comprises the TM4, TM5 TM6 and TM7 regions of the GPCR. |
| FILED | Thursday, May 16, 2013 |
| APPL NO | 13/896115 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 14/723 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/23 (20130101) C07K 2319/24 (20130101) C07K 2319/35 (20130101) C07K 2319/43 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101) C12N 2799/026 (20130101) Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889378 | Kranz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Kranz (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University in St. Louis (St. Louis, Missouri) |
| INVENTOR(S) | Robert Kranz (St. Louis, Missouri) |
| ABSTRACT | The invention provides methods for identifying a compound that inhibits cytochrome c synthesis. This invention further provides a method for the high throughput screening of compounds that inhibit cytochrome c synthesis. |
| FILED | Wednesday, July 07, 2010 |
| APPL NO | 12/831643 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 2333/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889414 | Alivisatos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | A. Paul Alivisatos (Oakland, California); Carolyn A. Larabell (Oakland, California); Wolfgang J. Parak (Dachau, Germany); Mark Le Gros (Oakland, California); Rosanne Boudreau (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | A. Paul Alivisatos (Oakland, California); Carolyn A. Larabell (Oakland, California); Wolfgang J. Parak (Dachau, Germany); Mark Le Gros (Oakland, California); Rosanne Boudreau (Berkeley, California) |
| ABSTRACT | Methods for determining metabolic properties of living cells through the uptake of semiconductor nanocrystals by cells. Generally the methods require a layer of neutral or hydrophilic semiconductor nanocrystals and a layer of cells seeded onto a culture surface and changes in the layer of semiconductor nanocrystals are detected. The observed changes made to the layer of semiconductor nanocrystals can be correlated to such metabolic properties as metastatic potential, cell motility or migration. |
| FILED | Wednesday, October 30, 2002 |
| APPL NO | 10/285187 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 23/20 (20130101) C12M 41/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) G01N 33/5005 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/853 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889418 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Fei Ran (Boston, Massachusetts) |
| ABSTRACT | The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are compositions and methods related to components of a CRISPR complex particularly comprising a Cas ortholog enzyme. |
| FILED | Monday, June 02, 2014 |
| APPL NO | 14/293674 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/85 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889419 | Williams |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David A Williams (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | David A Williams (Indianapolis, Indiana) |
| ABSTRACT | A method to increase the efficiency of transduction of hematopoietic and other cells by retroviruses includes infecting the cells in the presence of fibronectin or fibronectin fragments. The fibronectin and fibronectin fragments significantly enhance retroviral-mediated gene transfer into the cells, particularly hematopoietic cells including committed progenitors and primitive hematopoietic stem cells. The invention also provides improved methods for somatic gene therapy capitalizing on enhanced gene transfer, hematopoietic cellular populations, and novel constructs for enhancing retroviral-mediated DNA transfer into cells and their use. |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/859487 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Peptides C07K 14/78 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 5/0647 (20130101) C12N 15/86 (20130101) C12N 2501/58 (20130101) C12N 2510/00 (20130101) C12N 2740/13043 (20130101) C12N 2740/13045 (20130101) C12N 2810/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889426 | Mohammadi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York); Anna V. Eliseenkova (Stamford, Connecticut) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York); Anna V. Eliseenkova (Stamford, Connecticut) |
| ABSTRACT | The present invention is directed to a method of treating hypophosphatemia in a subject. The present invention is also directed to a method of screening for compounds suitable for treatment of hypophosphatemia associated with elevated or normal FGF23. This method involves providing FGF23, FGFR-Klotho complex, and one or more candidate compounds. The FGF23, the FGFR-Klotho complex, and the candidate compounds are combined under conditions effective for the FGF23 and the binary FGFR-Klotho complex to form a ternary complex if present by themselves. This method also involves identifying the candidate compounds, which prevent formation of the complex as being potentially suitable in treating hypophosphatemic conditions associated with elevated or normal FGF23. A method of screening the specificity of compounds which prevent formation of the FGF23-Klotho-FGFR complex is also disclosed. |
| FILED | Friday, May 18, 2012 |
| APPL NO | 13/475094 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/59 (20130101) A61K 38/17 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/84 (20130101) G01N 30/00 (20130101) G01N 33/68 (20130101) G01N 33/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889430 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lily Yang (Decatur, Georgia); Hui Mao (Alpharetta, Georgia); Shuming Nie (Atlanta, Georgia); Xiaohu Gao (Shoreline, Washington) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Lily Yang (Decatur, Georgia); Hui Mao (Alpharetta, Georgia); Shuming Nie (Atlanta, Georgia); Xiaohu Gao (Shoreline, Washington) |
| ABSTRACT | A nanostructure and methods of synthesizing same. In one embodiment, the nanostructure includes a magnetic iron oxide nanoparticle, a hydrophobic protection structure including at least an amphiphilic copolymer, wherein the hydrophobic protection structure encapsulates the magnetic iron oxide nanoparticle, and at least one amino-terminal fragment (ATF) peptide or epidermal growth factor receptor (EGFR) antibody conjugated to the amphiphilic copolymer. |
| FILED | Friday, May 04, 2007 |
| APPL NO | 12/299079 |
| ART UNIT | 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0034 (20130101) A61K 49/0056 (20130101) A61K 49/0058 (20130101) A61K 49/0093 (20130101) A61K 49/1866 (20130101) A61K 2039/505 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/77 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889597 | Cairns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nigel J. Cairns (St. Louis, Missouri); Robert H Baloh (St. Louis, Missouri); Alan Pestronk (St. Louis, Missouri); Michael A. Gitcho (St. Louis, Missouri); Alison M. Goate (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Nigel J. Cairns (St. Louis, Missouri); Robert H Baloh (St. Louis, Missouri); Alan Pestronk (St. Louis, Missouri); Michael A. Gitcho (St. Louis, Missouri); Alison M. Goate (St. Louis, Missouri) |
| ABSTRACT | The present invention provides nucleic acids and peptides, and methods of using the nucleic acids and peptides to identify subjects at risk for a TDP-43 proteinopathy. The invention also provides for an army comprising the nucleic acids and peptides of the invention. |
| FILED | Friday, January 30, 2009 |
| APPL NO | 12/865659 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889615 | Tomic-Canic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marjana Tomic-Canic (Miami, Florida); Harold Brem (Bronx, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Marjana Tomic-Canic (Miami, Florida); Harold Brem (Bronx, New York) |
| ABSTRACT | Compositions for antagonizing phosphorylation and subsequent degradation of glycogen synthase kinase 3 beta (GSK3β) in epidermal cells are disclosed. GSK3β phosphorylation antagonists include molecules that function to inhibit or reduce the binding activity or enzymatic activity of an upstream signaling molecule leading to GSK3β phosphorylation, or by downregulating the expression of one or more upstream signaling molecules involved in regulating GSK3β phosphorylation. Methods of using the GSK3β phosphorylation antagonists to inhibit or reduce the phosphorylation and degradation of GSK3β in epidermal cells are provided. The methods are useful to promote epithelialization and closure of wounds, such as chronic non-healing wounds. |
| FILED | Wednesday, December 29, 2010 |
| APPL NO | 13/519551 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) Original (OR) Class A61K 31/136 (20130101) A61K 31/366 (20130101) A61K 31/4741 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889620 | Klagsbrun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Klagsbrun (Newton, Massachusetts); Shay Soker (Greensboro, North Carolina) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Michael Klagsbrun (Newton, Massachusetts); Shay Soker (Greensboro, North Carolina) |
| ABSTRACT | The present invention provides isolated polypeptides having VEGF antagonist activity, pharmaceutical compositions and methods of treatment. The polypeptides of the invention include polypeptides comprising a portion of SEQ ID NO: 1 having VEGF antagonist activity, polypeptides comprising SEQ ID NO: 2 or a portion thereof having VEGF antagonist activity, and a polypeptide having the structure of formula (I), set forth above. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity. |
| FILED | Friday, February 03, 2012 |
| APPL NO | 13/365373 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) Peptides C07K 14/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889621 | Mohammadi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York); Anna V. Eliseenkova (Stamford, Connecticut) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Moosa Mohammadi (Scarsdale, New York); Regina Goetz (New York, New York); Anna V. Eliseenkova (Stamford, Connecticut) |
| ABSTRACT | The present invention is directed to a method of treating hypophosphatemia in a subject. This method involves selecting a subject with hypophosphatemia associated with elevated or normal FGF23 and administering to the selected subject an inhibitor of FGF23-Klotho-FGF receptor complex formation under conditions effective to treat the hypophosphatemia. |
| FILED | Friday, October 29, 2010 |
| APPL NO | 12/915801 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/59 (20130101) A61K 38/17 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/84 (20130101) G01N 30/00 (20130101) G01N 33/68 (20130101) G01N 33/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889622 | Thio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kwee Liu Lin Thio (St. Louis, Missouri); Kelvin A. Yamada (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Kwee Liu Lin Thio (St. Louis, Missouri); Kelvin A. Yamada (St. Louis, Missouri) |
| ABSTRACT | The present invention relates to methods of inhibiting seizure in a subject. In particular, the invention provides methods of increasing brain leptin levels in a subject. |
| FILED | Friday, July 25, 2008 |
| APPL NO | 12/179856 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 38/2264 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889631 | Peterson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Blake R. Peterson (Lawrence, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Blake R. Peterson (Lawrence, Kansas) |
| ABSTRACT | A delivery system for introducing a cargo molecule into cytosol of a living cell can include: a first membrane binding element linked to an endosomal compartment disrupting element through a first linker having one or more anionic moieties; and a second membrane binding element linked to an exogenous cargo molecule through a second linker having one or more anionic moieties, the second linker having a region that is selectively cleavable, wherein the first and second membrane binding elements both induce endocytosis into an early/recycling endosome and the endosomal compartment disrupting element destabilizes the early/recycling endosome such that the exogenous cargo molecule is released from the second membrane binding element and into the cytosol of the living cell. |
| FILED | Tuesday, August 18, 2009 |
| APPL NO | 12/543313 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48123 (20130101) A61K 47/48338 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889634 | Nudler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Evgeny A. Nudler (New York, New York); Ruslan R. Rafikov (Evans, Georgia) |
| ABSTRACT | This invention discloses isolated short peptides comprising the amino acid sequence Cys-Glu-Phe-His (CEFH; SEQ ID NOS: 1 and 15) and analogs thereof as well as compositions comprising CEFH peptides and analogs thereof. The CEFH peptides disclosed herein are effective in mediating the denitration of 3-nitrotyrosines (3-NT) in cellular proteins thereby preventing tissue damage associated with excess nitric oxide (NO) and its reactive species. The CEFH peptides disclosed herein are useful in the treatment of ischemia/reperfusion (I/R) injury and other disorders. |
| FILED | Thursday, January 31, 2013 |
| APPL NO | 13/755093 |
| ART UNIT | 1676 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 5/126 (20130101) Original (OR) Class C07K 5/1013 (20130101) C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889635 | Baker, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James R. Baker, Jr. (Ann Arbor, Michigan); Xue-min Cheng (Ann Arbor, Michigan); Abraham F. L. Van Der Spek (Ann Arbor, Michigan); Baohua Mark Huang (Ann Arbor, Michigan); Thommey P. Thomas (Dexter, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | James R. Baker, Jr. (Ann Arbor, Michigan); Xue-min Cheng (Ann Arbor, Michigan); Abraham F. L. Van Der Spek (Ann Arbor, Michigan); Baohua Mark Huang (Ann Arbor, Michigan); Thommey P. Thomas (Dexter, Michigan) |
| ABSTRACT | The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer-linker conjugates, methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer-linker conjugates of the present invention may further comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy. |
| FILED | Wednesday, September 30, 2009 |
| APPL NO | 12/570977 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 47/483 (20130101) Original (OR) Class A61K 47/48207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889638 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Seth M. Cohen (San Marcos, California); Jody L. Major Jourden (Atlanta, Georgia) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Seth M. Cohen (San Marcos, California); Jody L. Major Jourden (Atlanta, Georgia) |
| ABSTRACT | Set forth herein, inter alia, are compositions and methods for treating diseases with prodrugs. Provided herein are prodrug compositions for inhibiting the function of proteins, compositions and methods for treating diseases associated with oxidative compounds, oxidatively-sensitive prodrugs of inhibitors of metalloproteases. and methods of inhibiting metalloproteases using oxidatively-sensitive prodrugs. |
| FILED | Wednesday, June 22, 2011 |
| APPL NO | 13/166796 |
| ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889639 | Spiegelman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jiandie Lin (Ann Arbor, Michigan); Christopher B. Newgard (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Jiandie Lin (Ann Arbor, Michigan); Christopher B. Newgard (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention provides methods for treating lipid-related diseases and disorders, e.g., hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, cardiovascular disease, obesity, and type II diabetes, and for modulating lipid biosynthesis, lipid transport, plasma triglyceride levels and/or plasma cholesterol levels, by modulating the expression or activity of PGC-1β. Methods for identifying compounds which are capable of treating or preventing a lipid-related disease or disorder are also described. |
| FILED | Friday, October 21, 2005 |
| APPL NO | 11/577614 |
| ART UNIT | 1674 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889641 | Asokan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aravind Asokan (Chapel Hill, North Carolina); Richard Jude Samulski (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Aravind Asokan (Chapel Hill, North Carolina); Richard Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention provides AAV capsid proteins (VP1, VP2 and/or VP3) comprising a modification in the amino acid sequence in the three-fold axis loop 4 and virus capsids and virus vectors comprising the modified AAV capsid protein. In particular embodiments, the modification comprises a substitution of one or more amino acids at amino acid positions 585 to 590 (inclusive) of the native AAV2 capsid protein sequence or the corresponding positions of other AAV capsid proteins. The invention also provides methods of administering the virus vectors and virus capsids of the invention to a cell or to a subject in vivo. |
| FILED | Thursday, February 11, 2010 |
| APPL NO | 13/201154 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889658 | Hostetler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Karl Y. Hostetler (Del Mar, California); James R. Beadle (San Diego, California) |
| ABSTRACT | The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and the like. |
| FILED | Monday, October 21, 2013 |
| APPL NO | 14/059365 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/48 (20130101) Original (OR) Class C07F 9/404 (20130101) C07F 9/405 (20130101) C07F 9/3873 (20130101) C07F 9/5728 (20130101) C07F 9/65121 (20130101) C07F 9/65616 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/04 (20130101) C07H 19/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889660 | Palczewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Krzysztof Palczewski (Bay Village, Ohio); Radu Moise (Cleveland, Ohio) |
| ABSTRACT | In one aspect of the present invention, a pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of (R)-all-trans-13,14-dihydroretinol and a pharmaceutically acceptable carrier or diluent. In another aspect of the present invention, pharmaceutical composition for treating a metabolic disease in a mammalian subject includes a therapeutically effective amount of (S)-all-trans-13,14-dihydroretinol and a pharmaceutically acceptable carrier or diluent. In a further aspect of the present invention, a method is provided for treating a metabolic disease in a mammalian subject. The method includes administering to the subject a pharmaceutical composition comprising at least one all-trans-13,14-dihydroretinoid, all-trans-13,14-dihydroretinoid derivative, or agent capable of modulating the level of at least one all-trans-13,14-dihydroretinoid or all-trans-13,14-dihydroretinoid derivative in the subject. |
| FILED | Friday, November 16, 2012 |
| APPL NO | 13/679592 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/07 (20130101) Original (OR) Class A61K 31/203 (20130101) A61K 31/215 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/909 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889672 | Antonetti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David A. Antonetti (Ann Arbor, Michigan); Paul Titchenell (Hershey, Pennsylvania) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | David A. Antonetti (Ann Arbor, Michigan); Paul Titchenell (Hershey, Pennsylvania) |
| ABSTRACT | The invention provides a method of inhibiting atypical protein kinase C (aPKC) comprising contacting an aPKC with a compound having a structure selected from the group consisting of structural formulas (I) to (IX). The invention further provides a method of inhibiting or reducing vascular permeability. The method comprising administering to a subject a composition comprising an amount of a compound having a structure selected from the group consisting of structural formulas (I) to (IX) effective to inhibit or reduce vascular permeability. A method of treating or preventing a disease or disorder characterized by abnormal vascular permeability, a method of inhibiting angiogenesis, a method of inhibiting cancer cell proliferation, a formulation, and a method of preparing a formulation also are provided. |
| FILED | Friday, April 27, 2012 |
| APPL NO | 13/458990 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/381 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/4025 (20130101) A61K 31/4436 (20130101) A61K 31/4535 (20130101) A61K 31/5377 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889680 | Krysan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Damian Krysan (Pittsford, New York); Louis DiDone (Rochester, New York); Bonnie K. Baxter (Fairport, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Damian Krysan (Pittsford, New York); Louis DiDone (Rochester, New York); Bonnie K. Baxter (Fairport, New York) |
| ABSTRACT | Provided are methods of treating or preventing a fungal infection in a subject. The methods comprise identifying a subject with or at risk of developing a fungal infection and administering to the subject a therapeutically effective amount of an inhibitor or a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof. Inhibition of the fungal PDK-1 or homolog thereof results in the treatment or prevention of a fungal infection in the subject. Also provided are compositions comprising an inhibitor of a fungal phosphoinositide-dependent kinase 1 (PDK-1) or a homolog thereof, and a pharmaceutically acceptable carrier. |
| FILED | Thursday, November 17, 2011 |
| APPL NO | 13/298766 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/243 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889689 | Hromas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Hromas (Gainesville, Florida); Andrei Leitao (Sao Carlos, Brazil); Tudor I. Oprea (Albuquerque, New Mexico); Larry A. Sklar (Albuquerque, New Mexico); Elizabeth A. Williamson (Gainesville, Florida); Justin Wray (Albuquerque, New Mexico); Wei Wang (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Robert Hromas (Gainesville, Florida); Andrei Leitao (Sao Carlos, Brazil); Tudor I. Oprea (Albuquerque, New Mexico); Larry A. Sklar (Albuquerque, New Mexico); Elizabeth A. Williamson (Gainesville, Florida); Justin Wray (Albuquerque, New Mexico); Wei Wang (Albuquerque, New Mexico) |
| ABSTRACT | This invention relates to novel cancer treatment compositions and associated therapeutic methods. More particularly, this invention relates in part to small chemical bifunctional inhibitors of DNA replication and repair proteins Metnase and/or Intnase (also termed Gypsy Integrase, Gypsy Integrease-1, Gypsy Retransposon Integrase 1, or GIN-I) that simultaneously damage DNA, and to a therapeutic method that utilizes the inhibitors to increase the effectiveness of cancer treatment protocols, including radiation therapy. In preferred embodiments, compounds, compositions and methods of treatment of the invention are used to treat a patient suffering from leukemia (e.g. acute myeloid leukemia (AML) and related cancers. In certain aspects of such treatments, compounds, compositions and methods of treatment of the invention are administered as a monotherapy (in some cases, to patients who have exhibited resistance to Topo IIalpha inhibitors such as VP-16), or are co-administered with a Topo IIalpha inhibitor or other anti-cancer agents as otherwise described herein or in combination with radiation therapy. |
| FILED | Wednesday, January 26, 2011 |
| APPL NO | 13/574941 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/47 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 215/56 (20130101) Original (OR) Class C07D 401/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889705 | Joshi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Harish C. Joshi (Decatur, Georgia); Ritu Aneja (Lilburn, Georgia); Surya N. Vangapandu (Smyrna, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Harish C. Joshi (Decatur, Georgia); Ritu Aneja (Lilburn, Georgia); Surya N. Vangapandu (Smyrna, Georgia) |
| ABSTRACT | Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are noscapine analogs. The compounds and compositions can be used to treat and/or prevent a wide variety of cancers, including drug resistant cancers. While the antitussive plant alkaloid, noscapine, binds tubulin, displays anticancer activity, and has a safe pharmacological profile in humans, structure-function analyzes pointed to a proton at position 9 of the isoquinoline ring that can be modified without compromising tubulin binding activity. Noscapine analogs with various functional moieties at position 9 on the isoquinoline ring kill human cancer cells resistant to other anti-microtubule agents, such as vincas and taxanes. |
| FILED | Tuesday, June 05, 2012 |
| APPL NO | 13/488621 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4741 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 491/056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889706 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Jae Won Chang (Boston, Massachusetts); Jianming Zhang (Cambridge, Massachusetts); Carson C. Thoreen (Jamaica Plain, Massachusetts); Seong Woo Anthony Kang (Cambridge, Massachusetts); David M. Sabatini (Cambridge, Massachusetts); Qingsong Liu (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to small molecule modulators of mTORC1 and mTORC2, syntheses thereof, and intermediates thereto. Such small molecule modulators are useful in the treatment of proliferative diseases (e.g., benign neoplasms, cancers, inflammatory diseases, autoimmune diseases, diabetic retinopathy) and metabolic diseases. Novel small molecules are provided that inhibit one or more of mTORC1, mTORC2, and PI3K-related proteins. Novel methods of providing soluble mTORC1 and mTORC2 complexes are discussed, as well as methods of using the soluble complexes in a high-throughput manner to screen for inhibitory compounds. |
| FILED | Tuesday, November 06, 2012 |
| APPL NO | 13/670013 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 471/14 (20130101) C07D 498/04 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889713 | Redda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida A and M University (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida A and M University (Tallahassee, Florida) |
| INVENTOR(S) | Kinfe Ken Redda (Tallahassee, Florida); Madhavi Gangapuram (Tallahassee, Florida) |
| ABSTRACT | The compounds herein disclosed are N-substituted tetrahydroisoquinoline benzamide and benzene sulfonamide compounds that have modifications on the phenyl rings by introducing groups with various electronic properties. These derivatives of N-substituted tetrahydroisoquinoline compounds have been shown to have anti-proliferative activity against cells. In particular, the compounds have been found to be effective in inhibiting the proliferation of cancer cells, such as cancer cells that originated in breast tissue. Additionally, it has been shown that the novel compounds have IC50 values against the breast cancer cells that are 6- to 10-fold less than the IC50 of Tamoxifen. |
| FILED | Wednesday, August 07, 2013 |
| APPL NO | 13/960886 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 217/08 (20130101) Original (OR) Class C07D 417/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889739 | Mozaffarian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dariush Mozaffarian (Boston, Massachusetts); Haiming Cao (Bethesda, Maryland); Gokhan S. Hotamisligil (Wellesley, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Dariush Mozaffarian (Boston, Massachusetts); Haiming Cao (Bethesda, Maryland); Gokhan S. Hotamisligil (Wellesley, Massachusetts) |
| ABSTRACT | The present invention provides for a novel lipokine, trans-C16:1n7-palmitoleate, which also serves as a biomarker for metabolic status. More specifically, low concentrations of trans-C16:1n7-palmitoleate the serum indicates a risk of metabolic disease. Additionally, administering trans C16:1n7-palmitoleate to a subject (via pharmaceutical, nutraceutical, or other means), positively impacts glucose metabolism. |
| FILED | Monday, July 11, 2011 |
| APPL NO | 13/809181 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 1/296 (20130101) A23L 1/3006 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/20 (20130101) Acyclic or Carbocyclic Compounds C07C 57/03 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889743 | Davey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert A. Davey (Galveston, Texas); Andrey A. Kolokoltsov (Galveston, Texas); Mohammad F. Saeed (League City, Texas) |
| ASSIGNEE(S) | Board of Regents, University of Texas System (Austin, Texas) |
| INVENTOR(S) | Robert A. Davey (Galveston, Texas); Andrey A. Kolokoltsov (Galveston, Texas); Mohammad F. Saeed (League City, Texas) |
| ABSTRACT | The present invention discloses method to treat infections caused by filovirus. Such a method comprises blocking the PI3 kinase pathway or the calcium-associated pathway at the gene or protein level. Also disclosed herein are the compounds useful in the treatment of filoviral infection. |
| FILED | Monday, December 21, 2009 |
| APPL NO | 12/653916 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/277 (20130101) A61K 31/366 (20130101) Original (OR) Class A61K 31/435 (20130101) A61K 31/554 (20130101) A61K 31/713 (20130101) A61K 31/4741 (20130101) A61K 31/5377 (20130101) A61K 33/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889744 | Arbiser |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jack L. Arbiser (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jack L. Arbiser (Atlanta, Georgia) |
| ABSTRACT | Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are hexafluoro-honokiol analogs. The compounds and compositions can be used to treat and/or prevent a wide variety of cancers, including drug resistant cancers. Representative hexafluoro-honokiol analogs include hexafluoro-honokiol, analogs in which one or both hydroxy groups are replaced with dichloroacetate esters, and analogs with increased fluorination. The compounds are believed to function, at least, by inhibiting angiogenesis and/or inducing apoptosis. Thus, the compounds are novel therapeutic agents for a variety of cancers. |
| FILED | Tuesday, June 22, 2010 |
| APPL NO | 13/380109 |
| ART UNIT | 1671 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 39/373 (20130101) Original (OR) Class C07C 69/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889757 | Muratoglu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Orhun K. Muratoglu (Cambridge, Massachusetts); Ebru Oral (Newton, Massachusetts) |
| ABSTRACT | The present invention relates to methods for making oxidation resistant homogenized polymeric materials and medical implants that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and annealing the anti-oxidant doped UHMWPE in a super critical fluid, and materials used therein. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/799247 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/28 (20130101) C08J 5/00 (20130101) Original (OR) Class C08J 2300/00 (20130101) C08J 2323/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889791 | Guan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jianjun Guan (Pittsburgh, Pennsylvania); William R. Wagner (Wexford, Pennsylvania); Kazuro Lee Fujimoto (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jianjun Guan (Pittsburgh, Pennsylvania); William R. Wagner (Wexford, Pennsylvania); Kazuro Lee Fujimoto (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided are novel biocompatible copolymers and compositions comprising the copolymers. The copolymers and degradation products thereof are non-toxic and typically have an LCST between room temperature and 37° C. so that they are liquid at room temperature and gelled at 37° C. which facilitates their use in humans, for example for wound treatment and as a cellular growth matrix or niche. The copolymer comprises numerous ester linkages in its backbone so that the copolymers are erodeable in situ. Degradation products of the polymer are soluble and non-toxic. The copolymer is amine-reactive so that it can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymer. |
| FILED | Wednesday, October 10, 2007 |
| APPL NO | 11/869774 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 47/34 (20130101) A61K 47/482 (20130101) Original (OR) Class A61K 47/48176 (20130101) A61K 47/48784 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) A61L 27/16 (20130101) A61L 27/3873 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 265/00 (20130101) C08F 265/04 (20130101) C08F 265/10 (20130101) C08F 290/06 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) C08L 51/003 (20130101) C08L 51/003 (20130101) C08L 2666/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889836 | Supattapone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Surachai Supattapone (Hanover, New Hampshire); Michael B. Miller (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Surachai Supattapone (Hanover, New Hampshire); Michael B. Miller (Hanover, New Hampshire) |
| ABSTRACT | The present invention is method for non-covalently immobilizing an infectious prion protein using a magnetic substrate. |
| FILED | Wednesday, June 08, 2011 |
| APPL NO | 13/702673 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 17/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 33/54326 (20130101) G01N 2800/2828 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/92 (20130101) Y10S 977/705 (20130101) Y10S 977/838 (20130101) Y10S 977/904 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889842 | Gin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David Y. Gin (Pelham, New York); Michelle Adams (New York, New York); Kai Deng (Guilderland, New York); Nicholas Perl (New York, New York); Annie Won (Groton, New York); Philip Livingston (New York, New York); Govind Ragupathi (New York, New York) |
| ASSIGNEE(S) | Sloan-Kettering Insititute for Cancer Research (New York, New York) |
| INVENTOR(S) | David Y. Gin (Pelham, New York); Michelle Adams (New York, New York); Kai Deng (Guilderland, New York); Nicholas Perl (New York, New York); Annie Won (Groton, New York); Philip Livingston (New York, New York); Govind Ragupathi (New York, New York) |
| ABSTRACT | The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation. |
| FILED | Thursday, September 13, 2012 |
| APPL NO | 13/613312 |
| ART UNIT | 1673 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/7024 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/08 (20130101) C07H 15/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889846 | Sass et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Philip M. Sass (Audubon, Pennsylvania); Nicholas C. Nicolaides (Boothwyn, Pennsylvania); Luigi Grasso (Bala Cynwyd, Pennsylvania); Marc Berger (Yardley, Pennsylvania); Tao Sai (Foster City, California) |
| ASSIGNEE(S) | Morphotek, Inc. (Exton, Pennsylvania) |
| INVENTOR(S) | Philip M. Sass (Audubon, Pennsylvania); Nicholas C. Nicolaides (Boothwyn, Pennsylvania); Luigi Grasso (Bala Cynwyd, Pennsylvania); Marc Berger (Yardley, Pennsylvania); Tao Sai (Foster City, California) |
| ABSTRACT | This invention provides antibodies that specifically bind and neutralize Staphylococcus enterotoxin B. In addition, nucleic acids encoding such antibodies, and cells that express such antibodies are provided. Also provided are methods for treating diseases mediated by, and for neutralizing Staphylococcus enterotoxin B. |
| FILED | Monday, July 02, 2012 |
| APPL NO | 13/540330 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1271 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889850 | Nudler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Evgeny A. Nudler (New York, New York); Ilya Shamovsky (New Providence, New Jersey) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Evgeny A. Nudler (New York, New York); Ilya Shamovsky (New Providence, New Jersey) |
| ABSTRACT | The present invention is directed to molecules that inhibit expression or a function of a eukaryotic Heat Shock RNA (HSR1) and their use for inhibiting a stress response or stress tolerance in a cell. |
| FILED | Thursday, October 13, 2011 |
| APPL NO | 13/272920 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/113 (20130101) C12N 15/8218 (20130101) Original (OR) Class C12N 15/8271 (20130101) C12N 15/8273 (20130101) C12N 15/8279 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2330/10 (20130101) C12N 2500/46 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889857 | Bruno et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nicholas C. Bruno (California, Maryland); Stephen L. Buchwald (Newton, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Nicholas C. Bruno (California, Maryland); Stephen L. Buchwald (Newton, Massachusetts) |
| ABSTRACT | Described are palladium precatalysts, and methods of making and using them. The palladium precatalysts show improved stability and improved reactivity in comparison to previously-described palladium precatalysts. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/799620 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 37/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/28 (20130101) C07F 15/006 (20130101) Original (OR) Class C07F 15/0086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889863 | Johnston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffrey N. Johnston (Nashville, Tennessee); Tyler A. Davis (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Jeffrey N. Johnston (Nashville, Tennessee); Tyler A. Davis (Nashville, Tennessee) |
| ABSTRACT | The present invention provides methods and intermediates are provided for the preparation of (−)-Nutlin-3. Methods and intermediates are also provided for the enantioselective addition of aryl nitromethanes to aldimines. Bis(amidine) catalysts for the use in these and other reactions are also provided. |
| FILED | Thursday, July 14, 2011 |
| APPL NO | 13/183202 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 269/06 (20130101) Original (OR) Class C07C 269/06 (20130101) C07C 271/14 (20130101) C07C 271/14 (20130101) Heterocyclic Compounds C07D 215/42 (20130101) C07D 403/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890522 | Busse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Reed Frederick Busse (Madison, Wisconsin); James Holmes (Madison, Wisconsin); Philip James Beatty (Thornhill, Canada); Kang Wang (Madison, Wisconsin); Frank Korosec (Middleton, Wisconsin) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Reed Frederick Busse (Madison, Wisconsin); James Holmes (Madison, Wisconsin); Philip James Beatty (Thornhill, Canada); Kang Wang (Madison, Wisconsin); Frank Korosec (Middleton, Wisconsin) |
| ABSTRACT | The present disclosure is intended to describe embodiments for improving image data acquisition and processing in accelerated dynamic magnetic resonance imaging sequences. One embodiment is described where a method includes an acquisition sequence configured to acquire an undersampled set of magnetic resonance data. The undersampled set of magnetic resonance data has a pseudo-random sampling pattern within a data space acquired at a first time, the pseudo-random sampling pattern being influenced by other pseudo-random sampling patterns within the data space arising from the acquisition of additional undersampled sets of magnetic resonance data at respective times. In some embodiments, the pseudo-random sampling patterns of the undersampled sets of magnetic resonance data interleave to yield a desired sampling pattern. |
| FILED | Friday, March 18, 2011 |
| APPL NO | 13/051924 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4818 (20130101) G01R 33/5611 (20130101) G01R 33/56308 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890946 | Publicover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nelson G. Publicover (Reno, Nevada); Jason Heffernan (Reno, Nevada) |
| ASSIGNEE(S) | Eyefluence, Inc. (Reno, Nevada) |
| INVENTOR(S) | Nelson G. Publicover (Reno, Nevada); Jason Heffernan (Reno, Nevada) |
| ABSTRACT | A scene illumination system is provided that produces spatially uniform or controlled brightness levels for machine vision applications. The system includes a camera, multiple light sources that preferentially illuminate different regions within the camera's field-of-view, and a processing unit coupled to the camera and light sources. Focal regions of the light sources within the camera's field-of-view are sampled to determine average regional brightness and compared to target brightness levels. The processing unit controls the light sources to increase or decrease illumination levels to converge toward the target brightness levels within the field-of-view. This modulation of the light sources may be repeated with successive video images until target brightness levels are achieved. Once achieved, the iterative feedback control may be locked-in for some applications, while for others, the iterative process may continue periodically or continuously to account for different scenes or changes in lighting conditions. |
| FILED | Monday, March 01, 2010 |
| APPL NO | 12/715177 |
| ART UNIT | 2444 — Computer Networks |
| CURRENT CPC | Television 348/78 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892198 | Bohorquez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jose L. Bohorquez (Miramar, Florida); Al-Thaddeus Avestruz (Waltham, Massachusetts); Michael D. Rinehart (Quincy, Massachusetts); Seward Rutkove (Brookline, Massachusetts); Elmer C. Lupton (Charlestown, Massachusetts) |
| ASSIGNEE(S) | Skulpt, Inc. (Davie, Florida) |
| INVENTOR(S) | Jose L. Bohorquez (Miramar, Florida); Al-Thaddeus Avestruz (Waltham, Massachusetts); Michael D. Rinehart (Quincy, Massachusetts); Seward Rutkove (Brookline, Massachusetts); Elmer C. Lupton (Charlestown, Massachusetts) |
| ABSTRACT | Embodiments of devices and methods for evaluating tissue are disclosed. In one embodiment, a method for measuring a characteristic of a tissue may include passing a current through the tissue, measuring a signal corresponding to the voltage resulting from passing the current through the tissue, analyzing current passed through the tissue and resulting voltage to determine the electrical characteristics of the tissue; and analyzing the electrical characteristics of the tissue to determine a status of the tissue. |
| FILED | Friday, April 27, 2012 |
| APPL NO | 13/823659 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/547 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08887548 | Price et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian L. Price (Panama City Beach, Florida); Patrick A. Delay (Panama City Beach, Florida); Mark Welscher (Panama City Beach, Florida) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brian L. Price (Panama City Beach, Florida); Patrick A. Delay (Panama City Beach, Florida); Mark Welscher (Panama City Beach, Florida) |
| ABSTRACT | A land mine simulator includes a housing having an opening formed in one end thereof. A plate movably supported in the housing's opening has a first face exposed to a surrounding environment and a second face exposed to an interior region of the housing. A non-compressible fluid-filled reservoir in the housing includes a flexible diaphragm opposing and spaced apart from the second face of the plate. Plungers are between each of the second face of the plate and the diaphragm. Each of one or more air spring in the housing includes a cylinder having a movable piston sealed therein with a first side of the piston in fluid communication with the reservoir's fluid and a second side of the piston in fluid communication with a pressurized volume of gas within the cylinder. A pressure sensor is provided in communication with the fluid in the reservoir. |
| FILED | Wednesday, August 22, 2012 |
| APPL NO | 13/591624 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/1.150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887567 | Dwyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul W. Dwyer (Seattle, Washington); Arthur Savchenko (Morristown, New Jersey); Fred Petri (Snohomish, Washington) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Paul W. Dwyer (Seattle, Washington); Arthur Savchenko (Morristown, New Jersey); Fred Petri (Snohomish, Washington) |
| ABSTRACT | An accelerometer includes a base, a proof mass flexibly connected to the base, and a double-ended tuning fork (DETF) coupled to the proof mass and the base. The DETF includes a base attached to the accelerometer base, an outrigger that extends from a first side of the base, and two tines that extend from a side of the outrigger that is opposite the first side of the base. The accelerometer also includes a drive mechanism that generates opposing forces in different halves of the outrigger, thereby causing the tines to oscillate. An excitation voltage applied to metallized traces on the outrigger at the base of the DETF cause the tines to resonant. The alternating strains generated at the root of the tines excite the tines themselves at their resonant frequency without the requirement of complex metallization applied to the tines. |
| FILED | Tuesday, December 20, 2011 |
| APPL NO | 13/331934 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/504.160 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887613 | Griffin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brittany C. Griffin (Madison, Alabama); Jeremy A. Belcher (Huntsville, Alabama); Justin R. Harrison (Madison, Alabama); Brock Birdsong (Pulaski, Tennessee) |
| ABSTRACT | The application relates to a missile launch rail device including: a missile launch rail and a latch for attaching and releasing a missile situated on the missile launch rail, a latch pin inserted through both two latch pin holes and two rail pin holes positioned approximately halfway between the cam end and the spring end and a pin retainer securely mounted to the missile launch rail, the pin retainer including a latch pin catch which holds the latch pin in place to restrict radial pressure by the pin on inside surfaces of the two latch holes and inside surfaces of the two rail pin holes from pressure created by the missile on the latch, thus substantially preventing premature disabling of the missile launch rail and the latch by wear on the latch holes and the rail pin holes. |
| FILED | Monday, September 30, 2013 |
| APPL NO | 14/041448 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 3/0406 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887614 | Carreiro |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul J. Carreiro (Swansea, Massachusetts) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul J. Carreiro (Swansea, Massachusetts) |
| ABSTRACT | A submarine buoyant payload launcher system includes support rails extending longitudinally along an interior surface of a submarine missile capsule. A plurality of hold downs are spaced along the length of each rail and are retractable into the support rails. Once a payload is in position within the rails, the hold downs adjacent to the top end of the payload are rotated to their closed position, so as to contact the payload. Another payload can then be loaded within the rails until the payload contacts with the closed hold downs. As in the case of the first payload, the hold downs adjacent to the top end of this next payload are rotated to their closed position. Multiple payloads can be loaded within the rails in this manner. |
| FILED | Tuesday, May 14, 2013 |
| APPL NO | 13/893487 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887640 | Knight et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ryan R. Knight (Chevy Chase, Maryland); Oliver M. Barham (Washington, District of Columbia); Thinh Q. Hoang (Beltsville, Maryland); Robert H. Wood (Laurel, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ryan R. Knight (Chevy Chase, Maryland); Oliver M. Barham (Washington, District of Columbia); Thinh Q. Hoang (Beltsville, Maryland); Robert H. Wood (Laurel, Maryland) |
| ABSTRACT | A safety fuze includes a magneto striker generator (MSG) as its a power generation source. The MSG provides energy to energize an electronic unit and a safety and arming device. The safety fuze allows safety and arming of military hand grenades, with a fully out-of-line explosive initiator and an integrated power generation means, for improving safety and performance. The MSG includes a striker and a receiving bobbin that houses a conductive coil. The striker comprises a permanent magnet that is mounted on a pivot mechanism for allowing a rotational displacement of the permanent magnet, into the bobbin, in order to generate an electrical current. As the permanent magnet is being inserted inside the bobbin, the magnetic flux change induces an electric current in the coil, creating the necessary energy for the fuze operation. |
| FILED | Monday, September 10, 2012 |
| APPL NO | 13/608494 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Domestic Stoves or Ranges for Solid Fuels; Implements for Use in Connection With Stoves or Ranges F24B 27/00 (20130101) Domestic Stoves or Ranges; Details of Domestic Stoves or Ranges, of General Application F24C 11/02 (20130101) F24C 11/003 (20130101) F24C 11/06 (20130101) F24C 15/20 (20130101) F24C 15/40 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/008 (20130101) Original (OR) Class F42C 14/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887641 | Manole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leon Manole (Great Meadows, New Jersey); Arthur Ricardo Pizza (Maywood, New Jersey); Ernest Lee Logsdon (Newton, New Jersey); Gary Anthony Pacella (Stroudsburg, Pennsylvania); Anthony J. Sebasto (Budd Lake, New Jersey); Wilfredo Toledo (Hasbrouck Heights, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Leon Manole (Great Meadows, New Jersey); Arthur Ricardo Pizza (Maywood, New Jersey); Ernest Lee Logsdon (Newton, New Jersey); Gary Anthony Pacella (Stroudsburg, Pennsylvania); Anthony J. Sebasto (Budd Lake, New Jersey); Wilfredo Toledo (Hasbrouck Heights, New Jersey) |
| ABSTRACT | A 40 mm ammunition projectile for firing without significant spin in an M203 or an M320 grenade launcher. The ammunition includes a projectile body having hollow inner cavity therein for an explosive warhead; a projectile fin assembly; a projectile nose element having a conically shaped front area thereon; a decoupled projectile sabot in two or more joining sabot petals enclosing the body; a base cartridge case having vent holes, a bowl area for placement of a copper closure cup containing propellant therein, and a closure plug for threading into the rear of said cartridge case. The projectile fin assembly may provide a canted angle on each fin blade to (relatively very slowly) spin up the round at less than 30 Hz. Projectiles with body length less than five inches may be launched in an M203 grenade launcher while projectiles with body length up to eight inches may be launched in an M320 grenade launcher. |
| FILED | Thursday, February 07, 2013 |
| APPL NO | 13/761736 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 14/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887719 | Billingsley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Britton G. Billingsley (St. Paul, Minnesota); David M. Blomberg (Lino Lakes, Minnesota); Joy L. Manske (Menomonie, Wisconsin) |
| ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
| INVENTOR(S) | Britton G. Billingsley (St. Paul, Minnesota); David M. Blomberg (Lino Lakes, Minnesota); Joy L. Manske (Menomonie, Wisconsin) |
| ABSTRACT | A filtering device 10 that includes a housing 12 having a plurality of subsections 32, 34, and 36 where each subsection is adapted to receive a filter element 26, 28, and 30. An inlet 18 is disposed at a first location on the housing 12, and an upstream air distribution system is placed in fluid communication with the inlet 18 and with each of the subsections 32, 34, and 36. A downstream air distribution system is located in fluid communication with each subsection 32, 34, and 36, and an outlet 20 in fluid communication with the downstream air distribution system. The upstream and downstream air distribution systems are constructed to cause the same airflow velocity through each subsection. Using such a construction, overall product service life may be increased while minimizing pressure resistance of the total filter. |
| FILED | Thursday, December 15, 2011 |
| APPL NO | 13/326377 |
| ART UNIT | 3778 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Surgery 128/201.250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888935 | Grix et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles E. Grix (Citrus Heights, California); Wayne N. Sawka (Reno, California) |
| ASSIGNEE(S) | Digital Solid State Propulsion, LLC (Reno, Nevada) |
| INVENTOR(S) | Charles E. Grix (Citrus Heights, California); Wayne N. Sawka (Reno, California) |
| ABSTRACT | A composition capable of producing either solid propellant grains, liquid or gel monopropellants, all of which are electrically ignitable and capable of sustained controllable combustion at ambient pressure. Additional compositions capable of sustained controllable combustion at elevated pressures are described. Applications for the compositions disclosed herein are provided, and include among other applications use in small micro thrusters, large core-burning solid propellant gains, shaped explosives charges for military application, and pumpable liquids and gel monopropellants or explosives for military, commercial mining or gas and oil recovery. In alternative embodiments the above compositions may also incorporate an energetic nitrate polymer, bum rate modifiers, and/or metal fuel(s). The HIPEP formulation makes it possible to ignite and sustain combustion at ambient and vacuum conditions (a) without continuous electrical power and (b) while providing faster bum rates. |
| FILED | Friday, May 15, 2009 |
| APPL NO | 12/993084 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/001 (20130101) C06B 23/006 (20130101) C06B 23/007 (20130101) C06B 31/00 (20130101) C06B 47/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889028 | Snyder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | G. Jeffrey Snyder (Pasadena, California); Aaron LaLonde (Pasadena, California); Yanzhong Pei (Pasadena, California); Heng Wang (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | G. Jeffrey Snyder (Pasadena, California); Aaron LaLonde (Pasadena, California); Yanzhong Pei (Pasadena, California); Heng Wang (Pasadena, California) |
| ABSTRACT | The present invention demonstrates that weak scattering of carriers leads to a high mobility and therefore helps achieve low electric resistivity with high Seebeck coefficient for a thermoelectric material. The inventors demonstrate this effect by obtaining a thermoelectric figure of merit, zT, higher than 1.3 at high temperatures in n-type PbSe, because of the weak scattering of carriers in the conduction band as compared with that in the valence band. The invention further demonstrates favorable thermoelectric transport properties of n-type PbTe1-xIx with carrier concentrations ranging from 5.8×1018-1.4×1020 cm−3. |
| FILED | Thursday, May 03, 2012 |
| APPL NO | 13/463726 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2006/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class H01L 35/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889127 | Muro Galindo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Silvia Muro Galindo (Madrid, Spain); Vladimir R. Muzykantov (Warminster, Pennsylvania); Edward Howard Schuchman (Haworth, New Jersey) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Silvia Muro Galindo (Madrid, Spain); Vladimir R. Muzykantov (Warminster, Pennsylvania); Edward Howard Schuchman (Haworth, New Jersey) |
| ABSTRACT | The present invention relates to compositions and methods for delivering lysosomal proteins. The compositions and methods described herein permit the targeted delivery of exogenous lysosomal proteins to cell surface proteins that allow their internalization via non-clathrin pathways. The present invention further relates to the use of the compositions and methods for enzyme replacement therapy of lysosomal storage diseases. Nucleic acids, recombinant cells and kits useful for making and using the compositions of the invention are also provided. |
| FILED | Friday, July 01, 2005 |
| APPL NO | 11/631248 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/48561 (20130101) Peptides C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889257 | Rolison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Debra R Rolison (Arlington, Virginia); Jeffrey W Long (Alexandria, Virginia); Christopher N. Chervin (Arlington, Virginia); Justin C Lytle (Tacoma, Washington); Katherine A. Pettigrew (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Debra R Rolison (Arlington, Virginia); Jeffrey W Long (Alexandria, Virginia); Christopher N. Chervin (Arlington, Virginia); Justin C Lytle (Tacoma, Washington); Katherine A. Pettigrew (Alexandria, Virginia) |
| ABSTRACT | An article having: a nonconductive fiber and a RuO2 coating. A method of: immersing a nonconductive article in a solution of RuO4 and a nonpolar solvent at a temperature that is below the temperature at which RuO4 decomposes to RuO2 in the nonpolar solvent in the presence of the article; and warming the article and solution to ambient temperature under ambient conditions to cause the formation of a RuO2 coating on a portion of the article. An article having: a nonconductive fiber and a coating. The coating is made by electroless deposition, sputtering, atomic-layer deposition, chemical vapor deposition, or physical vapor deposition. |
| FILED | Monday, October 06, 2008 |
| APPL NO | 12/245978 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/1216 (20130101) Original (OR) Class C23C 18/1225 (20130101) C23C 18/1245 (20130101) C23C 18/1283 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 8/0236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889414 | Alivisatos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | A. Paul Alivisatos (Oakland, California); Carolyn A. Larabell (Oakland, California); Wolfgang J. Parak (Dachau, Germany); Mark Le Gros (Oakland, California); Rosanne Boudreau (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | A. Paul Alivisatos (Oakland, California); Carolyn A. Larabell (Oakland, California); Wolfgang J. Parak (Dachau, Germany); Mark Le Gros (Oakland, California); Rosanne Boudreau (Berkeley, California) |
| ABSTRACT | Methods for determining metabolic properties of living cells through the uptake of semiconductor nanocrystals by cells. Generally the methods require a layer of neutral or hydrophilic semiconductor nanocrystals and a layer of cells seeded onto a culture surface and changes in the layer of semiconductor nanocrystals are detected. The observed changes made to the layer of semiconductor nanocrystals can be correlated to such metabolic properties as metastatic potential, cell motility or migration. |
| FILED | Wednesday, October 30, 2002 |
| APPL NO | 10/285187 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 23/20 (20130101) C12M 41/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) G01N 33/5005 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/853 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889421 | Ouellette et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne Ouellette (Waldorf, Maryland); John H. Wilkinson (Waldorf, Maryland); James N. Thomasson, III (Alexandria, Virginia); Frederick S. Heim (Pearisburg, Virginia); Herbert Mitchell (Severna Park, Maryland); Robert G. Best (Burke, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Wayne Ouellette (Waldorf, Maryland); John H. Wilkinson (Waldorf, Maryland); James N. Thomasson, III (Alexandria, Virginia); Frederick S. Heim (Pearisburg, Virginia); Herbert Mitchell (Severna Park, Maryland); Robert G. Best (Burke, Virginia) |
| ABSTRACT | The present invention relates generally to a kit and method for the colorimetric detection of precursors used in the assembly of homemade explosives (HMEs). More specifically, the present invention relates to a bulk HME precursor detection kit and methods of using a kit that is capable of bulk detection of HME precursors, such as urea nitrate, ammonium nitrate and potassium chlorate. |
| FILED | Wednesday, August 24, 2011 |
| APPL NO | 13/137521 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889429 | Cao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Y. Charles Cao (Gainesville, Florida); Huimeng Wu (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Y. Charles Cao (Gainesville, Florida); Huimeng Wu (Gainesville, Florida) |
| ABSTRACT | A dual-interaction ligand for rendering otherwise hydrophobic nanoparticles water soluble or suspendable has a hydrophilic base with a plurality of hydrophilic segments extending from a core of the base, where at least one segment or the core contains a hydrophobic groups capable of forming van der Waal interaction between hydrophobic groups of the dual-interaction ligand and other hydrophobic ligands, and at least one complexing functionality to complex a metal atom or ion of a nanoparticle. The dual-interaction ligands can be combined with hydrophobic nanoparticles, where the dual-interaction ligands can displace some or all of the hydrophobic ligands of the hydrophobic nanoparticles, to form a nanoparticle-dual interaction ligand complex that can be dissolved or dispersed readily in an aqueous solution. The dual interaction ligand can be functionalized to attach an antibody or other biomolecules such that the nanoparticle dual-interaction ligands complexes can contain biomolecules. Such biomolecules modified nanoparticle dual-interaction ligands can be used for sensing, labeling, optical imaging, magnetic resonance imaging, cell separation, and treatment of diseases. |
| FILED | Wednesday, January 28, 2009 |
| APPL NO | 12/865056 |
| ART UNIT | 1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) G01N 33/54353 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889430 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lily Yang (Decatur, Georgia); Hui Mao (Alpharetta, Georgia); Shuming Nie (Atlanta, Georgia); Xiaohu Gao (Shoreline, Washington) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Lily Yang (Decatur, Georgia); Hui Mao (Alpharetta, Georgia); Shuming Nie (Atlanta, Georgia); Xiaohu Gao (Shoreline, Washington) |
| ABSTRACT | A nanostructure and methods of synthesizing same. In one embodiment, the nanostructure includes a magnetic iron oxide nanoparticle, a hydrophobic protection structure including at least an amphiphilic copolymer, wherein the hydrophobic protection structure encapsulates the magnetic iron oxide nanoparticle, and at least one amino-terminal fragment (ATF) peptide or epidermal growth factor receptor (EGFR) antibody conjugated to the amphiphilic copolymer. |
| FILED | Friday, May 04, 2007 |
| APPL NO | 12/299079 |
| ART UNIT | 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0034 (20130101) A61K 49/0056 (20130101) A61K 49/0058 (20130101) A61K 49/0093 (20130101) A61K 49/1866 (20130101) A61K 2039/505 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/77 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889635 | Baker, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James R. Baker, Jr. (Ann Arbor, Michigan); Xue-min Cheng (Ann Arbor, Michigan); Abraham F. L. Van Der Spek (Ann Arbor, Michigan); Baohua Mark Huang (Ann Arbor, Michigan); Thommey P. Thomas (Dexter, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | James R. Baker, Jr. (Ann Arbor, Michigan); Xue-min Cheng (Ann Arbor, Michigan); Abraham F. L. Van Der Spek (Ann Arbor, Michigan); Baohua Mark Huang (Ann Arbor, Michigan); Thommey P. Thomas (Dexter, Michigan) |
| ABSTRACT | The present invention relates to novel therapeutic and diagnostic dendrimers. In particular, the present invention is directed to dendrimer-linker conjugates, methods of synthesizing the same, compositions comprising the conjugates, as well as systems and methods utilizing the conjugates (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease (e.g., cancer) diagnosis and/or therapy, pain therapy, etc.)). Accordingly, dendrimer-linker conjugates of the present invention may further comprise one or more components for targeting, imaging, sensing, and/or providing a therapeutic or diagnostic material and/or monitoring response to therapy. |
| FILED | Wednesday, September 30, 2009 |
| APPL NO | 12/570977 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 47/483 (20130101) Original (OR) Class A61K 47/48207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889706 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Jae Won Chang (Boston, Massachusetts); Jianming Zhang (Cambridge, Massachusetts); Carson C. Thoreen (Jamaica Plain, Massachusetts); Seong Woo Anthony Kang (Cambridge, Massachusetts); David M. Sabatini (Cambridge, Massachusetts); Qingsong Liu (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to small molecule modulators of mTORC1 and mTORC2, syntheses thereof, and intermediates thereto. Such small molecule modulators are useful in the treatment of proliferative diseases (e.g., benign neoplasms, cancers, inflammatory diseases, autoimmune diseases, diabetic retinopathy) and metabolic diseases. Novel small molecules are provided that inhibit one or more of mTORC1, mTORC2, and PI3K-related proteins. Novel methods of providing soluble mTORC1 and mTORC2 complexes are discussed, as well as methods of using the soluble complexes in a high-throughput manner to screen for inhibitory compounds. |
| FILED | Tuesday, November 06, 2012 |
| APPL NO | 13/670013 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 471/14 (20130101) C07D 498/04 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889776 | Curry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Randy D. Curry (Columbia, Missouri); Kevin O'Connor (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Randy D. Curry (Columbia, Missouri); Kevin O'Connor (Columbia, Missouri) |
| ABSTRACT | The present invention relates to composite materials with a high dielectric constant and high dielectric strength and to methods of producing the composite materials. The composite materials have high dielectric constants at a range of high frequencies and possess robust mechanical properties and strengths, such that they may be machined to a variety of configurations. The composite materials also have high dielectric strengths for operation in high power and high energy density systems. In one embodiment, the composite material is composed of a trimodal distribution of ceramic particles, including barium titanate, barium strontium titanate (BST), or combinations thereof and a polymer binder. |
| FILED | Friday, March 23, 2012 |
| APPL NO | 13/428950 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/003 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/4682 (20130101) Original (OR) Class C04B 35/6316 (20130101) C04B 2235/483 (20130101) C04B 2235/5427 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5454 (20130101) C04B 2235/5472 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/30 (20130101) Compositions of Macromolecular Compounds C08L 101/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/12 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/206 (20130101) Antennas, i.e Radio Aerials H01Q 1/362 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890032 | Pruden |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gary L. Pruden (Somers, Connecticut) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Windsor Locks, Connecticut) |
| INVENTOR(S) | Gary L. Pruden (Somers, Connecticut) |
| ABSTRACT | Heater leads for a leading edge resistive heating element are configured to accommodate the relative movement of the propeller blades to adjust propeller blade pitch. The heater leads each include a static portion and a dynamic portion. The static portion remains fixed relative to the rotating propeller during operation and the dynamic portion moves with movements of the individual blades to adjust pitch. The length of the dynamic portion accommodates the limits of movement and includes features that provide the desired performance and operational life. |
| FILED | Friday, September 17, 2010 |
| APPL NO | 12/884597 |
| ART UNIT | 3742 — Organic Chemistry |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/02 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 15/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890052 | Denham |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Martin S. Denham (Bend, Oregon) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Martin S. Denham (Bend, Oregon) |
| ABSTRACT | According to one embodiment, a method includes generating a first clock signal and a second clock signal with non-overlapping clock phases. The method may further include latching, by a plurality of master latches of a shift register, a plurality of values at a plurality of inputs of the master latches in response to a particular type of logical transition of the first clock signal. The method also includes latching, by a plurality of slave latches of the shift register, a plurality of output values of the plurality of master latches at a plurality of inputs of the slave latches in response to a particular type of logical transition of the second clock signal. |
| FILED | Tuesday, February 21, 2012 |
| APPL NO | 13/401517 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Static Stores G11C 19/00 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/335 (20130101) H04N 5/355 (20130101) H04N 5/37455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890059 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark A. Johnson (Woodbridge, Connecticut); Michael Z. Kamrath (Hutchinson, Minnesota); Etienne Garand (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Mark A. Johnson (Woodbridge, Connecticut); Michael Z. Kamrath (Hutchinson, Minnesota); Etienne Garand (New Haven, Connecticut) |
| ABSTRACT | The present invention relates to mass spectrometry and infrared spectrometry and in particular, to a method of providing highly resolved infrared spectra of mass-selected, complex (e.g., biopolymer, polypeptide, organic chemical, an organometallic compound, a carbohydrate, a polynucleotide or oligonucleotide compound) ions to be obtained in a general fashion. |
| FILED | Tuesday, October 11, 2011 |
| APPL NO | 13/878892 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/33 (20130101) G01N 21/3504 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/10 (20130101) H01J 49/0031 (20130101) H01J 49/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890409 | Eden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | J. Gary Eden (Champaign, Illinois); Sung-Jin Park (Champaign, Illinois); Taek-Lim Kim (Champaign, Illinois); Kwang-Soo Kim (Champaign, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illnois (Urbana, Illinois) |
| INVENTOR(S) | J. Gary Eden (Champaign, Illinois); Sung-Jin Park (Champaign, Illinois); Taek-Lim Kim (Champaign, Illinois); Kwang-Soo Kim (Champaign, Illinois) |
| ABSTRACT | An array of microcavity plasma devices is formed in a unitary sheet of oxide with embedded microcavities or microchannels and encapsulated metal driving electrodes isolated by oxide from the microcavities or microchannels and arranged so as to generate sustain a plasma in the embedded microcavities or microchannels upon application of time-varying voltage when a plasma medium is contained in the microcavities or microchannels. |
| FILED | Thursday, May 14, 2009 |
| APPL NO | 12/991237 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 11/36 (20130101) H01J 61/86 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890538 | Ganesh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meena Ganesh (Clifton Park, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Meena Ganesh (Clifton Park, New York) |
| ABSTRACT | A system includes a sensor housing having a base portion, a lid portion, and a joining portion. The joining portion is configured to be wrapped around at least a portion of an electrical wire. The lid portion includes one end detachably coupled to a first end of the base portion and another end coupled to a second end of the base portion via the joining portion. A flexible coil sensor is disposed in the sensor housing; bonded substantially along the base portion and the joining portion and configured to generate a signal representative of a fault in the electrical wire. A processing device is disposed in the sensor housing and configured to detect and locate a fault in the electrical wire in response to the signal representative of the fault in the electrical wire generated by the flexible coil sensor. |
| FILED | Wednesday, February 09, 2011 |
| APPL NO | 13/023944 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/537 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890569 | Apalkov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dmytro Apalkov (San Jose, California); Eugene Chen (Fremont, California); Kaveh Milaninia (San Jose, California) |
| ASSIGNEE(S) | Samsung Electronics Co., Ltd. (Gyeonggi-Do, South Korea) |
| INVENTOR(S) | Dmytro Apalkov (San Jose, California); Eugene Chen (Fremont, California); Kaveh Milaninia (San Jose, California) |
| ABSTRACT | A method and system provide and program a nonvolatile logic device. The nonvolatile logic device includes input and output magnetic junctions and at least one magnetic junction between the input and output magnetic junctions. The input magnetic junction includes an input junction free layer having an input junction easy axis. The input magnetic junction may be switchable using a current driven through the magnetic junction. The output magnetic junction includes an output junction free layer having an output junction easy axis. Each of the magnetic junction(s) includes a free layer having an easy axis. The input magnetic junction is magnetically coupled to the output magnetic junction through the magnetic junction(s). In some aspects, the method includes switching the magnetic moment(s) of the input magnetic junction from a first state to a second state, applying and then removing magnetic field(s) along the hard axis of the at least one magnetic junction. |
| FILED | Wednesday, July 25, 2012 |
| APPL NO | 13/557376 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/224 (20130101) H01L 43/12 (20130101) Pulse Technique H03K 19/08 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890765 | Dinh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vincent V. Dinh (San Diego, California); Howard L Dyckman (La Jolla, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Vincent V. Dinh (San Diego, California); Howard L Dyckman (La Jolla, California) |
| ABSTRACT | An antenna having an active radome for beam steering and/or nulling in accordance with several embodiments can include at least one omni-directional radiating element, a radome surrounding the radiating element, and a network of conductive segments that can be placed between the radome and radiating element. A plurality of switches can interconnect the conductive segments to form the network. The switches can be FET, MOSFET and optical switches, and can be selectively closed when the element radiates or receives RF energy to selectively establish connectivity between the conductive segments, which can achieve a selective Yagi-like effect for the antenna. The conductive segments network can have any geometric profile when viewed in top plan, such as octagonal, square and the like, provided the segments surround the radiating element. A processor can be used to provide a control algorithm, which can contain non-transitory written directions that selectively activate and deactivate the switches. |
| FILED | Saturday, April 21, 2012 |
| APPL NO | 13/452840 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/872 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890946 | Publicover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nelson G. Publicover (Reno, Nevada); Jason Heffernan (Reno, Nevada) |
| ASSIGNEE(S) | Eyefluence, Inc. (Reno, Nevada) |
| INVENTOR(S) | Nelson G. Publicover (Reno, Nevada); Jason Heffernan (Reno, Nevada) |
| ABSTRACT | A scene illumination system is provided that produces spatially uniform or controlled brightness levels for machine vision applications. The system includes a camera, multiple light sources that preferentially illuminate different regions within the camera's field-of-view, and a processing unit coupled to the camera and light sources. Focal regions of the light sources within the camera's field-of-view are sampled to determine average regional brightness and compared to target brightness levels. The processing unit controls the light sources to increase or decrease illumination levels to converge toward the target brightness levels within the field-of-view. This modulation of the light sources may be repeated with successive video images until target brightness levels are achieved. Once achieved, the iterative feedback control may be locked-in for some applications, while for others, the iterative process may continue periodically or continuously to account for different scenes or changes in lighting conditions. |
| FILED | Monday, March 01, 2010 |
| APPL NO | 12/715177 |
| ART UNIT | 2444 — Computer Networks |
| CURRENT CPC | Television 348/78 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891290 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xueti Tang (Fremont, California); Jing Wu (San Jose, California) |
| ASSIGNEE(S) | Samsung Electronics Co., Ltd. (Gyeonggi-Do, South Korea) |
| INVENTOR(S) | Xueti Tang (Fremont, California); Jing Wu (San Jose, California) |
| ABSTRACT | A method and system for providing a magnetic junction residing on a substrate and usable in a magnetic device are described. The magnetic junction includes a first pinned layer, a first nonmagnetic spacer layer having a first thickness, a free layer, a second nonmagnetic spacer layer having a second thickness greater than the first thickness, and a second pinned layer. The first nonmagnetic spacer layer resides between the pinned layer and the free layer. The first pinned layer resides between the free layer and the substrate. The second nonmagnetic spacer layer is between the free layer and the second pinned layer. Further, the magnetic junction is configured such that the free layer is switchable between a plurality of stable magnetic states when a write current is passed through the magnetic junction. |
| FILED | Friday, March 11, 2011 |
| APPL NO | 13/045528 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/16 (20130101) G11C 11/1675 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891355 | Huttle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William M. Huttle (Fredericksburg, Virginia) |
| ABSTRACT | A communication device is provided for transmitting information incorporated into at least one message packet. The device includes components for encoding the message packet as a signal, which is afterwards transmitted and analyzed. The encoder assigns the message packet to correspond to a specific pulse width. The transmitter sends the signal across a channel. The processor parses the signal as corresponding to the specific pulse width subsequently decoded to obtain the message packet. |
| FILED | Tuesday, April 30, 2013 |
| APPL NO | 13/873268 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 25/4902 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891444 | Manz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul C. Manz (Andover, New Jersey); Fernando J. Maymi (Aguadilla, Puerto Rico); Manuel Rodriguez-Martinez (Cabo Rojo, Puerto Rico) |
| ASSIGNEE(S) | The United States of America as represened by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Paul C. Manz (Andover, New Jersey); Fernando J. Maymi (Aguadilla, Puerto Rico); Manuel Rodriguez-Martinez (Cabo Rojo, Puerto Rico) |
| ABSTRACT | A method on a first mobile node for facilitating exchange of pertinent data between mobile nodes over a wireless communications network can be provided. The method can include establishing, by the first mobile node, a wireless network connection with at least one other mobile node inside a predefined geospatial area, wherein the wireless network connection is established over the wireless communications network. The method can further include determining that a future position of the first mobile node is outside the predefined geospatial area and transmitting pertinent data residing on the first mobile node over the wireless communications network exclusively to the at least one other mobile node inside the predefined geo spatial area, wherein the pertinent data is associated with the predefined geospatial area. |
| FILED | Wednesday, December 16, 2009 |
| APPL NO | 12/639279 |
| ART UNIT | 2464 — Multiplex and VoIP |
| CURRENT CPC | Wireless Communication Networks H04W 4/02 (20130101) H04W 40/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891573 | Zhang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yong-Hang Zhang (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents (Scottsdale, Arizona) |
| INVENTOR(S) | Yong-Hang Zhang (Scottsdale, Arizona) |
| ABSTRACT | Use of semiconductor materials having a lattice constant of within +/−1.6% of 6.1 angstroms facilitates improved semiconductor device performance and new semiconductor structures, for example integration of field-effect devices and optoelectronic devices on a single wafer. High-mobility channels are enabled, improving device performance. |
| FILED | Monday, May 13, 2013 |
| APPL NO | 13/893232 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8252 (20130101) H01L 21/8254 (20130101) H01L 21/8258 (20130101) H01L 27/0605 (20130101) H01L 29/20 (20130101) H01L 29/22 (20130101) H01L 29/78 (20130101) H01L 29/267 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/0261 (20130101) H01S 5/323 (20130101) Original (OR) Class H01S 5/0425 (20130101) H01S 5/3009 (20130101) H01S 5/3095 (20130101) H01S 5/18361 (20130101) H01S 5/34306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891731 | Schmitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andrea Marie Schmitz (Niskayuna, New York); Gerald Bowden Wise (Clifton Park, New York); Michael Dermot Denvir (Albany, New York); Jeffrey Wayne Eberhard (Albany, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Andrea Marie Schmitz (Niskayuna, New York); Gerald Bowden Wise (Clifton Park, New York); Michael Dermot Denvir (Albany, New York); Jeffrey Wayne Eberhard (Albany, New York) |
| ABSTRACT | The subject matter disclosed herein relates to patient imaging systems, and more specifically, to portable X-ray imaging systems. In a first embodiment, a patient imaging system is presented. The patient imaging system includes an X-ray source configured to emit X-rays and a wireless X-ray detector configured to detect the emitted X-rays and acquire patient image data. The patient imaging system also includes an acquisition control system configured to initialize and prepare the patient imaging system for X-ray emission and detection. The acquisition control system is also configured to receive the acquired patient image data from the X-ray detector, and to non-deterministically control the operation of the X-ray source and the wireless X-ray detector. The patient imaging system also includes one or more user interfaces configured to instruct the acquisition control system when a user is ready for the patient imaging system to initialize, to prepare for X-ray emission and detection, and to begin X-ray emission and detection. |
| FILED | Wednesday, April 27, 2011 |
| APPL NO | 13/095658 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/54 (20130101) Original (OR) Class A61B 6/56 (20130101) A61B 6/548 (20130101) A61B 6/4405 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891831 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wei Chen (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Wei Chen (Potomac, Maryland) |
| ABSTRACT | Apparatus and methods are presented for estimating the velocity field based on a multi-image frame sequence having an integer number M frames, M is greater than two, in which a set of M−1 displaced frame difference (DFD) equations is solved using a set of iteration equations to determine a velocity field. |
| FILED | Tuesday, December 13, 2011 |
| APPL NO | 13/324073 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 7/0137 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891922 | Krug et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William P. Krug (Bellevue, Washington); Jocelyn Y. Takayesu (Tacoma, Washington); Michael Hochberg (Pasadena, California); Eric Y. Chan (Mercer Island, Washington) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | William P. Krug (Bellevue, Washington); Jocelyn Y. Takayesu (Tacoma, Washington); Michael Hochberg (Pasadena, California); Eric Y. Chan (Mercer Island, Washington) |
| ABSTRACT | A system and methods are disclosed for a hybrid silicon-organic scalable reconfigurable optical add-drop multiplexer. An embodiment of a scalable reconfigurable optical add-drop multiplexer (ROADM) includes an optical bus for optical signals of different wavelengths, a plurality of add/drop optical waveguides, and a plurality of ring resonators, each being optically coupled to the optical bus and to one of the add/drop optical waveguides. The ring resonators are coated with an organic electro-optic cladding layer and are configured to switch wavelength selected optical signals between the optical bus and the add/drop optical waveguides in response to control voltages applied to the organic electro-optic cladding layer. The individual ring resonators of the ROADM can be independently modulated and tuned to filter specific wavelengths. |
| FILED | Tuesday, September 04, 2007 |
| APPL NO | 11/849984 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12007 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/065 (20130101) G02F 1/3132 (20130101) Original (OR) Class G02F 2203/15 (20130101) G02F 2203/585 (20130101) Multiplex Communication H04J 14/021 (20130101) H04J 14/0212 (20130101) H04J 14/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892483 | Ezick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Ezick (Canonsburg, Pennsylvania); Richard A. Lethin (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | James Ezick (Canonsburg, Pennsylvania); Richard A. Lethin (New York, New York) |
| ABSTRACT | A plan representing a final solution to a problem is obtained efficiently, if the problem changes while being solved, by identifying the solution elements not affected by the change, and by reusing those solution elements. |
| FILED | Tuesday, May 31, 2011 |
| APPL NO | 13/149517 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892487 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leland Chang (New York, New York); Dharmendra S. Modha (San Jose, California); Robert K. Montoye (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Leland Chang (New York, New York); Dharmendra S. Modha (San Jose, California); Robert K. Montoye (Rochester, Minnesota) |
| ABSTRACT | Embodiments of the invention provide electronic synapse devices for reinforcement learning. An electronic synapse is configured for interconnecting a pre-synaptic electronic neuron and a post-synaptic electronic neuron. The electronic synapse comprises memory elements configured for storing a state of the electronic synapse and storing meta information for updating the state of the electronic synapse. The electronic synapse further comprises an update module configured for updating the state of the electronic synapse based on the meta information in response to an update signal for reinforcement learning. The update module is configured for updating the state of the electronic synapse based on the meta information, in response to a delayed update signal for reinforcement learning based on a learning rule. |
| FILED | Thursday, December 30, 2010 |
| APPL NO | 12/982505 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/27 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892619 | Galal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sameh Galal (Stanford, California); Mark Horowitz (Menlo Park, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Sameh Galal (Stanford, California); Mark Horowitz (Menlo Park, California) |
| ABSTRACT | A floating-point fused multiply-add (FMA) unit embodied in an integrated circuit includes a multiplier circuit cascaded with an adder circuit to produce a result A*C+B. To decrease latency, the FMA includes accumulation bypass circuits forwarding an unrounded result of the adder to inputs of the close path and the far path circuits of the adder, and forwarding an exponent result in carry save format to an input of the exponent difference circuit. Also included in the FMA is a multiply-add bypass circuit forwarding the unrounded result to the inputs of the multiplier circuit. The adder circuit includes an exponent difference circuit implemented in parallel with the multiplier circuit; a close path circuit implemented after the exponent difference circuit; and a far path circuit implemented after the exponent difference circuit. |
| FILED | Tuesday, July 24, 2012 |
| APPL NO | 13/556710 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 7/485 (20130101) G06F 7/4876 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892624 | Branson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Bradley W. Fawcett (Byron, Minnesota); Zhen Liu (Tarrytown, New York); William Waller (Laurel, Maryland); Fan Ye (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Bradley W. Fawcett (Byron, Minnesota); Zhen Liu (Tarrytown, New York); William Waller (Laurel, Maryland); Fan Ye (Yorktown Heights, New York) |
| ABSTRACT | A cooperative data stream processing system is provided that utilizes a plurality of independent, autonomous and possibly heterogeneous sites in a cooperative arrangement to process user-defined job requests over dynamic, continuous streams of data. A method is provided to organize the distributed sites into a plurality of virtual organizations that can be further combined and virtualized into virtualized virtual organizations. These virtualized virtual organizations can also include additional distributed sites and existing virtualized virtual organizations and all members of a given virtualized virtual organization can share data and processing resources in order to process jobs on either a task-based or goal-based allocation mechanism. The virtualized virtual organization is created dynamically using ad-hoc collaborations among the members and is arranged in either a federated or cooperative architecture. Collaborations between members is either tightly-coupled or loosely coupled. Flexible management of resources is provided with resources being provided under exclusive control or based on best-effort access. |
| FILED | Friday, May 11, 2007 |
| APPL NO | 11/747820 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5072 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892704 | Bronez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Bronez (Vienna, Virginia); Michelle Casagni (Great Falls, Virginia) |
| ASSIGNEE(S) | The Mitre Corporaton (McLean, Virginia) |
| INVENTOR(S) | Thomas Bronez (Vienna, Virginia); Michelle Casagni (Great Falls, Virginia) |
| ABSTRACT | Methods and systems for smart data processing and dissemination in wireless sensor networks are provided herein. In one aspect, the present invention provides dynamic and independent data processing and dissemination at individual sensor nodes in a wireless sensor network. In another aspect, the present invention provides data processing and/or dissemination methods at a sensor node that are responsive to, among other parameters, network traffic conditions, network connectivity conditions, conditions at the sensor node, and the data characteristics and QOS (Quality of Service) requirements of the data being processed and/or disseminated. In yet another aspect, data processing and/or dissemination rules according to the present invention are easily configurable and modifiable depending on the specific sensor networking application. |
| FILED | Friday, April 07, 2006 |
| APPL NO | 11/399387 |
| ART UNIT | 2456 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/24 (20130101) Original (OR) Class H04L 41/00 (20130101) H04L 41/12 (20130101) H04L 41/5051 (20130101) H04L 41/5077 (20130101) H04L 43/0811 (20130101) H04L 43/0852 (20130101) H04L 67/12 (20130101) Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893059 | Carroll |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KLA-Tencor Corporation (Milpitas, California) |
| ASSIGNEE(S) | KLA-Tencor Corporation (Milpitas, California) |
| INVENTOR(S) | Allen Carroll (San Jose, California) |
| ABSTRACT | One embodiment relates to a pattern data system for maskless electron beam lithography. The system includes a renderer that receives pre-exposure die image data, performs rendering of the pre-exposure die image data to generate raster data. The system further includes a plurality of data distributors communicatively coupled to the renderer. Each data distributor adapts the raster data to characteristics of an associated pattern writer. Other embodiments, aspects and feature are also disclosed. |
| FILED | Wednesday, January 30, 2013 |
| APPL NO | 13/754760 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 1/36 (20130101) Electric Digital Data Processing G06F 17/5068 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893126 | Arimilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lakshminarayana B. Arimilli (Austin, Texas); Ravi K. Arimilli (Austin, Texas); Guy L. Guthrie (Austin, Texas); Charles F. Marino (Round Rock, Texas); William J. Starke (Round Rock, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Ravi K. Arimilli (Austin, Texas); Guy L. Guthrie (Austin, Texas); Charles F. Marino (Round Rock, Texas); William J. Starke (Round Rock, Texas) |
| ABSTRACT | A heterogeneous processing element model is provided where I/O devices look and act like processors. In order to be treated like a processor, an I/O processing element, or other special purpose processing element, must follow some rules and have some characteristics of a processor, such as address translation, security, interrupt handling, and exception processing, for example. The heterogeneous processing element model puts special purpose processing elements on the same playing field as processors, from a programming perspective, operating system perspective, and power perspective. The operating system can get work to a security engine, for example, in the same way it does to a processor. |
| FILED | Friday, February 01, 2008 |
| APPL NO | 12/024220 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 13/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893148 | Arimilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lakshminarayana B. Arimilli (Austin, Texas); Ravi K. Arimilli (Austin, Texas); Ramakrishnan Rajamony (Austin, Texas); William E. Speight (Austin, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Lakshminarayana B. Arimilli (Austin, Texas); Ravi K. Arimilli (Austin, Texas); Ramakrishnan Rajamony (Austin, Texas); William E. Speight (Austin, Texas) |
| ABSTRACT | A system and method are provided for performing setup operations for receiving a different amount of data while processors are performing message passing interface (MPI) tasks. Mechanisms for adjusting the balance of processing workloads of the processors are provided so as to minimize wait periods for waiting for all of the processors to call a synchronization operation. An MPI load balancing controller maintains a history that provides a profile of the tasks with regard to their calls to synchronization operations. From this information, it can be determined which processors should have their processing loads lightened and which processors are able to handle additional processing loads without significantly negatively affecting the overall operation of the parallel execution system. As a result, setup operations may be performed while processors are performing MPI tasks to prepare for receiving different sized portions of data in a subsequent computation cycle based on the history. |
| FILED | Friday, June 15, 2012 |
| APPL NO | 13/524585 |
| ART UNIT | 2195 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/522 (20130101) Original (OR) Class G06F 9/5083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893157 | Carey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | James E. Carey (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota) |
| ABSTRACT | Administering incident pools including assigning an incident received from one or more components of the distributed processing system to a pool of incidents; assigning to each incident a particular combined minimum time for inclusion of the incident in the pool; in response to the pool closing, determining for each incident in the pool whether the incident has met its combined minimum time for inclusion in the pool; if the incident has been in the pool for its combined minimum time, including the incident in the closed pool; if the incident has not been in the pool for its combined minimum time, moving the incident from the closed pool to a next pool; applying incident suppression rules using the incidents assigned to the next pool; and applying incident creation rules to the incidents that were assigned to the next pool, while omitting any duplicate incidents caused by the assignment. |
| FILED | Tuesday, December 11, 2012 |
| APPL NO | 13/710523 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893273 | Honig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andrew Honig (East Windsor, New Jersey); Andrew Howard (Lansdale, Pennsylvania); Eleazar Eskin (Santa Monica, California); Salvatore J. Stolfo (Ridgewood, New Jersey) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Andrew Honig (East Windsor, New Jersey); Andrew Howard (Lansdale, Pennsylvania); Eleazar Eskin (Santa Monica, California); Salvatore J. Stolfo (Ridgewood, New Jersey) |
| ABSTRACT | A system and methods for detecting intrusions in the operation of a computer system comprises a sensor configured to gather information regarding the operation of the computer system, to format the information in a data record having a predetermined format, and to transmit the data in the predetermined data format. A data warehouse is configured to receive the data record from the sensor in the predetermined data format and to store the data in a SQL database. A detection model generator is configured to request data records from the data warehouse in the predetermined data format, to generate an intrusion detection model based on said data records, and to transmit the intrusion detection model to the data warehouse according to the predetermined data format. A detector is configured to receive a data record in the predetermined data format from the sensor and to classify the data record in real-time as one of normal operation and an attack based on said intrusion detection model. A data analysis engine is configured to request data records from the data warehouse according to the predetermined data format and to perform a data processing function on the data records. |
| FILED | Friday, May 25, 2007 |
| APPL NO | 11/805946 |
| ART UNIT | 2494 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/554 (20130101) G06F 21/566 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/14 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08887365 | Giesen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Isaac M. Giesen (Red Wing, Minnesota); Michael E. Cournoyer (Los Alamos, New Mexico); David G. Rael (Espanola, Minnesota) |
| ASSIGNEE(S) | Delaware Capital Formation, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Isaac M. Giesen (Red Wing, Minnesota); Michael E. Cournoyer (Los Alamos, New Mexico); David G. Rael (Espanola, Minnesota) |
| ABSTRACT | What is disclosed is a system for retrofitting a sealed enclosure for performing work therein having an outer enclosure assembly configured to be clamped to the outer annular face of a port ring and form a sealed engagement with the outer annular surface of the port ring, a change assembly having an inner ring and an access element wherein the inner ring has a first annular cylinder body that is sized to be slidably received by the port ring and the access element is configured to be sealably and slidably positioned within the first annular cylinder body of the inner ring. |
| FILED | Wednesday, October 28, 2009 |
| APPL NO | 12/607457 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 1/02 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887503 | Sonwane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chandrashekhar Sonwane (Canoga Park, California); Kenneth M. Sprouse (Canoga Park, California); Ganesan Subbaraman (Canoga Park, California); George M. O'Connor (Canoga Park, California); Gregory A. Johnson (Canoga Park, California) |
| ASSIGNEE(S) | Aerojet Rocketdyne of DE, Inc (Canoga Park, California) |
| INVENTOR(S) | Chandrashekhar Sonwane (Canoga Park, California); Kenneth M. Sprouse (Canoga Park, California); Ganesan Subbaraman (Canoga Park, California); George M. O'Connor (Canoga Park, California); Gregory A. Johnson (Canoga Park, California) |
| ABSTRACT | A power plant includes a closed loop, supercritical carbon dioxide system (CLS-CO2 system). The CLS-CO2 system includes a turbine-generator and a high temperature recuperator (HTR) that is arranged to receive expanded carbon dioxide from the turbine-generator. The HTR includes a plurality of heat exchangers that define respective heat exchange areas. At least two of the heat exchangers have different heat exchange areas. |
| FILED | Tuesday, December 13, 2011 |
| APPL NO | 13/323874 |
| ART UNIT | 3748 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 25/103 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08887572 | Turner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph A. Turner (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Joseph A. Turner (Lincoln, Nebraska) |
| ABSTRACT | A system and methods with which changes in microstructure properties such as grain size, grain elongation, texture, and porosity of materials can be determined and monitored over time to assess conditions such as stress and defects. An example system includes a number of ultrasonic transducers configured to transmit ultrasonic waves towards a target region on a specimen, a voltage source configured to excite the first and second ultrasonic transducers, and a processor configured to determine one or more properties of the specimen. |
| FILED | Tuesday, January 04, 2011 |
| APPL NO | 12/984291 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Auxiliary Equipment Specially Adapted for Railways, Not Otherwise Provided for B61K 9/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/12 (20130101) G01N 29/2418 (20130101) G01N 2291/102 (20130101) G01N 2291/2623 (20130101) G01N 2291/02881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888049 | Vander Lind |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Google Inc. (Mountain View, California) |
| ASSIGNEE(S) | Google Inc. (Mountain View, California) |
| INVENTOR(S) | Damon Vander Lind (Oakland, California) |
| ABSTRACT | A kite system with a ground station adapted for airborne power generation. The kite system may include a kite which includes one or more airfoils which have mounted thereon a plurality of turbine driven generators. The turbine driven generators may also function as motor driven propellers in a powered flight mode, which may be used during take-off, which may include aspects of vertical take-off and landing. A perch adapted to facilitate the take-off and landing may be used as part of the system. The perch may pivot such that the pivot is oriented towards the tension direction of the tether. |
| FILED | Tuesday, December 18, 2012 |
| APPL NO | 13/719198 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 31/06 (20130101) Original (OR) Class Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 3/00 (20130101) Wind Motors F03D 5/04 (20130101) F03D 11/04 (20130101) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2240/917 (20130101) F05B 2240/921 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/70 (20130101) Y02E 10/725 (20130101) Y02E 10/728 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888895 | Fisher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James C. Fisher (Morgantown, West Virginia); Ranjani V. Siriwardane (Morgantown, West Virginia); David A. Berry (Mount Morris, Pennsylvania); George A. Richards (Morgantown, West Virginia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | James C. Fisher (Morgantown, West Virginia); Ranjani V. Siriwardane (Morgantown, West Virginia); David A. Berry (Mount Morris, Pennsylvania); George A. Richards (Morgantown, West Virginia) |
| ABSTRACT | A method for the removal of H2O and CO2 from a gaseous stream comprising H2O and CO2, such as a flue gas. The method initially utilizes an H2O removal sorbent to remove some portion of the H2O, producing a dry gaseous stream and a wet H2O removal sorbent. The dry gaseous stream is subsequently contacted with a CO2 removal sorbent to remove some portion of the CO2, generating a dry CO2 reduced stream and a loaded CO2 removal sorbent. The loaded CO2 removal sorbent is subsequently heated to produce a heated CO2 stream. The wet H2O removal sorbent and the dry CO2 reduced stream are contacted in a first regeneration stage, generating a partially regenerated H2O removal sorbent, and the partially regenerated H2O removal sorbent and the heated CO2 stream are subsequently contacted in a second regeneration stage. The first and second stage regeneration typically act to retain an initial monolayer of moisture on the various removal sorbents and only remove moisture layers bound to the initial monolayer, allowing for relatively low temperature and pressure operation. Generally the applicable H2O sorption/desorption processes may be conducted at temperatures less than about 70° C. and pressures less than 1.5 atmospheres, with certain operations conducted at temperatures less than about 50° C. |
| FILED | Tuesday, September 10, 2013 |
| APPL NO | 14/022708 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/0462 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889010 | Silva et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James Manio Silva (Clifton Park, New York); Hope Matis (Schenectady, New York); William Leonard Kostedt, IV (Clifton Park, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | James Manio Silva (Clifton Park, New York); Hope Matis (Schenectady, New York); William Leonard Kostedt, IV (Clifton Park, New York) |
| ABSTRACT | A method for treating low barium frac water includes contacting a frac water stream with a radium selective complexing resin to produce a low radium stream, passing the low radium stream through a thermal brine concentrator to produce a concentrated brine; and passing the concentrated brine through a thermal crystallizer to yield road salt. |
| FILED | Monday, July 25, 2011 |
| APPL NO | 13/189864 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/00 (20130101) B01J 45/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) C02F 1/048 (20130101) C02F 1/66 (20130101) C02F 1/74 (20130101) C02F 1/683 (20130101) C02F 9/00 (20130101) Original (OR) Class C02F 2001/5218 (20130101) C02F 2101/006 (20130101) C02F 2101/203 (20130101) C02F 2101/206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889065 | Chelluri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bhanumathi Chelluri (Dublin, Ohio); Edward Arlen Knoth (Beavercreek, Ohio); Edward John Schumaker (Riverside, Ohio); Ryan D. Evans (N. Canton, Ohio); James. L. Maloney, III (Canton, Ohio) |
| ASSIGNEE(S) | IAP Research, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Bhanumathi Chelluri (Dublin, Ohio); Edward Arlen Knoth (Beavercreek, Ohio); Edward John Schumaker (Riverside, Ohio); Ryan D. Evans (N. Canton, Ohio); James. L. Maloney, III (Canton, Ohio) |
| ABSTRACT | An improved sintered material and product. A nanometer size reinforcement powder is mixed with a micron size titanium or titanium alloy powder. After the reinforcement powder is generally uniformly dispersed, the powder mixture is compacted and sintered, causing the nano reinforcement to react with the titanium or titanium alloy, producing a composite material containing nano and micron size precipitates that are uniformly distributed throughout the material. |
| FILED | Thursday, September 14, 2006 |
| APPL NO | 11/531771 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0014 (20130101) B22F 3/02 (20130101) B22F 3/10 (20130101) B22F 9/04 (20130101) B22F 2009/043 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Alloys C22C 1/1084 (20130101) Original (OR) Class C22C 32/0047 (20130101) C22C 32/0084 (20130101) C22C 47/14 (20130101) C22C 49/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889097 | Brooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kriston P. Brooks (Kennewick, Washington); Jamelyn D. Holladay (Kennewick, Washington); Kevin L. Simmons (Kennewick, Washington); Darrell R. Herling (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Kriston P. Brooks (Kennewick, Washington); Jamelyn D. Holladay (Kennewick, Washington); Kevin L. Simmons (Kennewick, Washington); Darrell R. Herling (Richland, Washington) |
| ABSTRACT | An on-board hydride storage system and process are described. The system includes a slurry storage system that includes a slurry reactor and a variable concentration slurry. In one preferred configuration, the storage system stores a slurry containing a hydride storage material in a carrier fluid at a first concentration of hydride solids. The slurry reactor receives the slurry containing a second concentration of the hydride storage material and releases hydrogen as a fuel to hydrogen-power devices and vehicles. |
| FILED | Monday, January 09, 2012 |
| APPL NO | 13/346613 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/065 (20130101) C01B 3/0073 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/065 (20130101) H01M 8/04216 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/324 (20130101) Y02E 60/362 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889221 | Sappok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Alexander Sappok (Cambridge, Massachusetts); Victor Wong (Peabody, Massachusetts) |
| ABSTRACT | Methods for generating and applying coatings to filters with porous material in order to reduce large pressure drop increases as material accumulates in a filter, as well as the filter exhibiting reduced and/or more uniform pressure drop. The filter can be a diesel particulate trap for removing particulate matter such as soot from the exhaust of a diesel engine. Porous material such as ash is loaded on the surface of the substrate or filter walls, such as by coating, depositing, distributing or layering the porous material along the channel walls of the filter in an amount effective for minimizing or preventing depth filtration during use of the filter. Efficient filtration at acceptable flow rates is achieved. |
| FILED | Tuesday, June 11, 2013 |
| APPL NO | 13/915014 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Separation B01D 39/2093 (20130101) B01D 46/057 (20130101) Original (OR) Class B01D 46/2418 (20130101) B01D 46/2455 (20130101) B01D 2239/0471 (20130101) B01D 2258/012 (20130101) B01D 2273/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889251 | Soules et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas F. Soules (Livermore, California); Raymond J. Beach (Livermore, California); Scott C. Mitchell (Escalon, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | Thomas F. Soules (Livermore, California); Raymond J. Beach (Livermore, California); Scott C. Mitchell (Escalon, California) |
| ABSTRACT | In one embodiment, a multilayer dielectric coating for use in an alkali laser includes two or more alternating layers of high and low refractive index materials, wherein an innermost layer includes a thicker, >500 nm, and dense, >97% of theoretical, layer of at least one of: alumina, zirconia, and hafnia for protecting subsequent layers of the two or more alternating layers of high and low index dielectric materials from alkali attack. In another embodiment, a method for forming an alkali resistant coating includes forming a first oxide material above a substrate and forming a second oxide material above the first oxide material to form a multilayer dielectric coating, wherein the second oxide material is on a side of the multilayer dielectric coating for contacting an alkali. |
| FILED | Wednesday, February 09, 2011 |
| APPL NO | 13/023841 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/10 (20130101) C23C 14/46 (20130101) C23C 14/081 (20130101) C23C 14/083 (20130101) C23C 16/401 (20130101) C23C 16/403 (20130101) C23C 16/405 (20130101) C23C 16/45555 (20130101) C23C 28/04 (20130101) Original (OR) Class C23C 28/042 (20130101) C23C 28/42 (20130101) C23C 28/44 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889301 | Balsara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nitash Pervez Balsara (El Cerrito, California); Hany Basam Eitouni (Berkeley, California); Ilan Gur (San Francisco, California); Mohit Singh (Berkeley, California); William Hudson (Berkeley, California) |
| ASSIGNEE(S) | Seeo, Inc. (Hayward, California) |
| INVENTOR(S) | Nitash Pervez Balsara (El Cerrito, California); Hany Basam Eitouni (Berkeley, California); Ilan Gur (San Francisco, California); Mohit Singh (Berkeley, California); William Hudson (Berkeley, California) |
| ABSTRACT | Nanostructured gel polymer electrolytes that have both high ionic conductivity and high mechanical strength are disclosed. The electrolytes have at least two domains—one domain contains an ionically-conductive gel polymer and the other domain contains a rigid polymer that provides structure for the electrolyte. The domains are formed by block copolymers. The first block provides a polymer matrix that may or may not be conductive on by itself, but that can soak up a liquid electrolyte, thereby making a gel. An exemplary nanostructured gel polymer electrolyte has an ionic conductivity of at least 1×10−4 S cm−1 at 25° C. |
| FILED | Friday, January 16, 2009 |
| APPL NO | 12/812214 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889303 | Meinhardt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kerry D. Meinhardt (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Kerry D. Meinhardt (Richland, Washington) |
| ABSTRACT | A cassette less SOFC assembly and a method for creating such an assembly. The SOFC stack is characterized by an electrically isolated stack current path which allows welded interconnection between frame portions of the stack. In one embodiment electrically isolating a current path comprises the step of sealing a interconnect plate to a interconnect plate frame with an insulating seal. This enables the current path portion to be isolated from the structural frame an enables the cell frame to be welded together. |
| FILED | Thursday, December 17, 2009 |
| APPL NO | 12/640280 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) Original (OR) Class G01R 33/4828 (20130101) G01R 33/5605 (20130101) G01R 33/5607 (20130101) G01R 33/56527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889342 | Qin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Yang Qin (Albuquerque, New Mexico); Robert B. Grubbs (Miller Place, New York); Young Suk Park (Torrance, California) |
| ABSTRACT | This disclosure relates to a polymer having the formula: wherein x is between 1 and about 100 an y is between about 99 and about 1, and x+Y=about 100. The disclosure also includes the use of the polymer in photovoltaic devices. |
| FILED | Thursday, February 06, 2014 |
| APPL NO | 14/174526 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/319 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889391 | Jessen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Holly Jean Jessen (Belgrade, Montana); Hans H. Liao (Eden Prairie, Minnesota); Steven John Gort (Apple Valley, Minnesota); Olga V. Selifonova (Plymouth, Minnesota) |
| ASSIGNEE(S) | Cargill, Incorporated (Wayzata, Minnesota) |
| INVENTOR(S) | Holly Jean Jessen (Belgrade, Montana); Hans H. Liao (Eden Prairie, Minnesota); Steven John Gort (Apple Valley, Minnesota); Olga V. Selifonova (Plymouth, Minnesota) |
| ABSTRACT | The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing such enzymes, as well as methods of their use, for example to produce malonyl semialdehyde and downstream products thereof, such as 3-hydroxypropionic acid and derivatives thereof. |
| FILED | Monday, September 12, 2011 |
| APPL NO | 13/230217 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/193 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889392 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chang-Jun Liu (Rocky Point, New York); Mohammad-Wadud Bhuiya (St. Louis, Missouri); Kewei Zhang (Middle Island, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Chang-Jun Liu (Rocky Point, New York); Mohammad-Wadud Bhuiya (St. Louis, Missouri); Kewei Zhang (Middle Island, New York) |
| ABSTRACT | Modified (iso)eugenol 4-O-methyltransferase enzymes having novel capacity for methylation of monolignols and reduction of lignin polymerization in plant cell wall are disclosed. Sequences encoding the modified enzymes are disclosed. |
| FILED | Friday, October 28, 2011 |
| APPL NO | 13/284148 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) Original (OR) Class C12N 15/8255 (20130101) Enzymes C12Y 201/01146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889414 | Alivisatos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | A. Paul Alivisatos (Oakland, California); Carolyn A. Larabell (Oakland, California); Wolfgang J. Parak (Dachau, Germany); Mark Le Gros (Oakland, California); Rosanne Boudreau (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | A. Paul Alivisatos (Oakland, California); Carolyn A. Larabell (Oakland, California); Wolfgang J. Parak (Dachau, Germany); Mark Le Gros (Oakland, California); Rosanne Boudreau (Berkeley, California) |
| ABSTRACT | Methods for determining metabolic properties of living cells through the uptake of semiconductor nanocrystals by cells. Generally the methods require a layer of neutral or hydrophilic semiconductor nanocrystals and a layer of cells seeded onto a culture surface and changes in the layer of semiconductor nanocrystals are detected. The observed changes made to the layer of semiconductor nanocrystals can be correlated to such metabolic properties as metastatic potential, cell motility or migration. |
| FILED | Wednesday, October 30, 2002 |
| APPL NO | 10/285187 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Original (OR) Class Apparatus for Enzymology or Microbiology; C12M 23/20 (20130101) C12M 41/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) G01N 33/5005 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/853 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889454 | McIntyre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Timothy J. McIntyre (Farragut, Tennessee); John T. Simpson (Clinton, Tennessee); David L. West (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Timothy J. McIntyre (Farragut, Tennessee); John T. Simpson (Clinton, Tennessee); David L. West (Oak Ridge, Tennessee) |
| ABSTRACT | Methods of manufacturing a thermoelectric generator via fiber drawing and corresponding or associated thermoelectric generator devices are provided. |
| FILED | Thursday, November 08, 2012 |
| APPL NO | 13/672446 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 37/028 (20130101) C03B 37/0122 (20130101) C03B 37/0279 (20130101) C03B 37/01214 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/28 (20130101) H01L 35/32 (20130101) H01L 35/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889589 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bingyun Li (Morgantown, West Virginia); Bingbing Jiang (Morgantown, West Virginia); McMahan L. Gray (Pittsburgh, Pennsylvania); Daniel J. Fauth (Pittsburgh, Pennsylvania); Henry W. Pennline (Bethel Park, Pennsylvania); George A. Richards (Morgantown, West Virginia) |
| ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia) |
| INVENTOR(S) | Bingyun Li (Morgantown, West Virginia); Bingbing Jiang (Morgantown, West Virginia); McMahan L. Gray (Pittsburgh, Pennsylvania); Daniel J. Fauth (Pittsburgh, Pennsylvania); Henry W. Pennline (Bethel Park, Pennsylvania); George A. Richards (Morgantown, West Virginia) |
| ABSTRACT | A solid sorbent for the capture and the transport of carbon dioxide gas is provided having at least one first layer of a positively charged material that is polyethylenimine or poly(allylamine hydrochloride), that captures at least a portion of the gas, and at least one second layer of a negatively charged material that is polystyrenesulfonate or poly(acryclic acid), that transports the gas, wherein the second layer of material is in juxtaposition to, attached to, or crosslinked with the first layer for forming at least one bilayer, and a solid substrate support having a porous surface, wherein one or more of the bilayers is/are deposited on the surface of and/or within the solid substrate. A method of preparing and using the solid sorbent is provided. |
| FILED | Tuesday, January 07, 2014 |
| APPL NO | 14/149210 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/62 (20130101) Original (OR) Class B01D 2253/25 (20130101) B01D 2253/202 (20130101) B01D 2257/504 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/26 (20130101) B01J 20/264 (20130101) B01J 20/327 (20130101) B01J 20/3272 (20130101) B01J 20/3289 (20130101) B01J 20/28014 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/04 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889623 | Hoeprich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul D. Hoeprich (Pleasanton, California); Nicholas O. Fischer (Livermore, California); Craig Blanchette (Moraga, California); Peter W. Mason (Somerville, Massachusetts) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Paul D. Hoeprich (Pleasanton, California); Nicholas O. Fischer (Livermore, California); Craig Blanchette (Moraga, California); Peter W. Mason (Somerville, Massachusetts) |
| ABSTRACT | Provided herein are immunostimulatory nanolipoprotein particles and related compositions methods and systems. |
| FILED | Thursday, October 22, 2009 |
| APPL NO | 12/604362 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/4833 (20130101) A61K 47/48853 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/799 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889908 | Madix et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert J. Madix (Lexington, Massachusetts); Ling Zhou (Cambridge, Massachusetts); Bingjun Xu (Cambridge, Massachusetts); Cynthia M. Friend (Lexington, Massachusetts); Cassandra G. Freyschlag (Colorado Springs, Colorado) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert J. Madix (Lexington, Massachusetts); Ling Zhou (Cambridge, Massachusetts); Bingjun Xu (Cambridge, Massachusetts); Cynthia M. Friend (Lexington, Massachusetts); Cassandra G. Freyschlag (Colorado Springs, Colorado) |
| ABSTRACT | The invention provides a method for producing amides via the reaction of aldehydes and amines with oxygen adsorbed on a metallic silver or silver alloy catalyst. An exemplary reaction is shown in Scheme 1: (I), (II), (III). |
| FILED | Tuesday, January 25, 2011 |
| APPL NO | 13/575150 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/215 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890081 | Watson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Scott A. Watson (Jemez Springs, New Mexico); Howard A. Bender, III (Santa Fe, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC. (Los Alamos, New Mexico) |
| INVENTOR(S) | Scott A. Watson (Jemez Springs, New Mexico); Howard A. Bender, III (Santa Fe, New Mexico) |
| ABSTRACT | A continuous imaging system for recording low levels of light typically extending over small distances with high-frame rates and with a large number of frames is described. Photodiode pixels disposed in an array having a chosen geometry, each pixel having a dedicated amplifier, analog-to-digital convertor, and memory, provide parallel operation of the system. When combined with a plurality of scintillators responsive to a selected source of radiation, in a scintillator array, the light from each scintillator being directed to a single corresponding photodiode in close proximity or lens-coupled thereto, embodiments of the present imaging system may provide images of x-ray, gamma ray, proton, and neutron sources with high efficiency. |
| FILED | Thursday, April 14, 2011 |
| APPL NO | 13/087314 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/32 (20130101) Original (OR) Class H04N 5/3745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890085 | De Geronimo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Gianluigi De Geronimo (Syosset, New York) |
| ABSTRACT | A method and apparatus for pulse pile-up rejection are disclosed. The apparatus comprises a delay value application constituent configured to receive a threshold-crossing time value, and provide an adjustable value according to a delay value and the threshold-crossing time value; and a comparison constituent configured to receive a peak-occurrence time value and the adjustable value, compare the peak-occurrence time value with the adjustable value, indicate pulse acceptance if the peak-occurrence time value is less than or equal to the adjustable value, and indicate pulse rejection if the peak-occurrence time value is greater than the adjustable value. |
| FILED | Thursday, October 31, 2013 |
| APPL NO | 14/068270 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/171 (20130101) Pulse Technique H03K 5/1532 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890115 | Sutter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eli Anguelova Sutter (Westhampton Beach, New York); Peter Werner Sutter (Westhampton Beach, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Eli Anguelova Sutter (Westhampton Beach, New York); Peter Werner Sutter (Westhampton Beach, New York) |
| ABSTRACT | Vapor-liquid-solid growth of nanowires is tailored to achieve complex one-dimensional material geometries using phase diagrams determined for nanoscale materials. Segmented one-dimensional nanowires having constant composition display locally variable electronic band structures that are determined by the diameter of the nanowires. The unique electrical and optical properties of the segmented nanowires are exploited to form electronic and optoelectronic devices. Using gold-germanium as a model system, in situ transmission electron microscopy establishes, for nanometer-sized Au—Ge alloy drops at the tips of Ge nanowires (NWs), the parts of the phase diagram that determine their temperature-dependent equilibrium composition. The nanoscale phase diagram is then used to determine the exchange of material between the NW and the drop. The phase diagram for the nanoscale drop deviates significantly from that of the bulk alloy. |
| FILED | Monday, June 18, 2012 |
| APPL NO | 13/526239 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02521 (20130101) H01L 21/02532 (20130101) H01L 21/02603 (20130101) H01L 21/02609 (20130101) H01L 21/02645 (20130101) H01L 21/02653 (20130101) H01L 29/0665 (20130101) Original (OR) Class H01L 29/0669 (20130101) H01L 29/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890323 | Stavis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Samuel M. Stavis (Ithaca, New York); Joshua B. Edel (Brookline, Massachusetts); Kevan T. Samiee (Ithaca, New York); Harold G. Craighead (Ithaca, New York) |
| ASSIGNEE(S) | Cornell Research Foundation (Ithaca, New York) |
| INVENTOR(S) | Samuel M. Stavis (Ithaca, New York); Joshua B. Edel (Brookline, Massachusetts); Kevan T. Samiee (Ithaca, New York); Harold G. Craighead (Ithaca, New York) |
| ABSTRACT | A nanofluidic channel fabricated in fused silica with an approximately 500 nm square cross section was used to isolate, detect and identify individual quantum dot conjugates. The channel enables the rapid detection of every fluorescent entity in solution. A laser of selected wavelength was used to excite multiple species of quantum dots and organic molecules, and the emission spectra were resolved without significant signal rejection. Quantum dots were then conjugated with organic molecules and detected to demonstrate efficient multicolor detection. PCH was used to analyze coincident detection and to characterize the degree of binding. The use of a small fluidic channel to detect quantum dots as fluorescent labels was shown to be an efficient technique for multiplexed single molecule studies. Detection of single molecule binding events has a variety of applications including high throughput immunoassays. |
| FILED | Tuesday, March 02, 2010 |
| APPL NO | 12/716087 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0056 (20130101) A61K 49/0067 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 10/00 (20130101) B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 438/962 (20130101) Y10S 977/70 (20130101) Y10S 977/774 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891073 | Effenberger, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andrew J. Effenberger, Jr. (San Diego, California); Jill R. Scott (Idaho Falls, Idaho); Timothy R. McJunkin (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Andrew J. Effenberger, Jr. (San Diego, California); Jill R. Scott (Idaho Falls, Idaho); Timothy R. McJunkin (Idaho Falls, Idaho) |
| ABSTRACT | In laser-induced breakdown spectroscopy (LIBS), an apparatus includes a pulsed laser configured to generate a pulsed laser signal toward a sample, a constructive interference object and an optical element, each located in a path of light from the sample. The constructive interference object is configured to generate constructive interference patterns of the light. The optical element is configured to disperse the light. A LIBS system includes a first and a second optical element, and a data acquisition module. The data acquisition module is configured to determine an isotope measurement based, at least in part, on light received by an image sensor from the first and second optical elements. A method for performing LIBS includes generating a pulsed laser on a sample to generate light from a plasma, generating constructive interference patterns of the light, and dispersing the light into a plurality of wavelengths. |
| FILED | Thursday, July 14, 2011 |
| APPL NO | 13/183228 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/18 (20130101) Original (OR) Class G01J 3/26 (20130101) G01J 3/443 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/718 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891371 | Archer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Joseph D. Ratterman (Seattle, Washington); Brian E. Smith (Knoxville, Tennessee) |
| ABSTRACT | Data communications in a parallel active messaging interface (‘PAMI’) of a parallel computer, the PAMI composed of data communications endpoints, each endpoint including a specification of data communications parameters for a thread of execution on a compute node, including specifications of a client, a context, and a task, endpoints coupled for data communications through the PAMI and through data communications resources, including receiving in an origin endpoint of the PAMI a SEND instruction, the SEND instruction specifying a transmission of transfer data from the origin endpoint to a first target endpoint; transmitting from the origin endpoint to the first target endpoint a Request-To-Send (‘RTS’) message advising the first target endpoint of the location and size of the transfer data; assigning by the first target endpoint to each of a plurality of target endpoints separate portions of the transfer data; and receiving by the plurality of target endpoints the transfer data. |
| FILED | Wednesday, November 14, 2012 |
| APPL NO | 13/676700 |
| ART UNIT | 2462 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891408 | Archer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Daniel A. Faraj (Rochester, Minnesota) |
| ABSTRACT | Methods, systems, and products are disclosed for broadcasting a message in a parallel computer that includes: transmitting, by the logical root to all of the nodes directly connected to the logical root, a message; and for each node except the logical root: receiving the message; if that node is the physical root, then transmitting the message to all of the child nodes except the child node from which the message was received; if that node received the message from a parent node and if that node is not a leaf node, then transmitting the message to all of the child nodes; and if that node received the message from a child node and if that node is not the physical root, then transmitting the message to all of the child nodes except the child node from which the message was received and transmitting the message to the parent node. |
| FILED | Friday, April 12, 2013 |
| APPL NO | 13/861963 |
| ART UNIT | 2475 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891575 | Snee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Preston T. Snee (Cambridge, Massachusetts); Yin Thai Chan (Cambridge, Massachusetts); Daniel G. Nocera (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Preston T. Snee (Cambridge, Massachusetts); Yin Thai Chan (Cambridge, Massachusetts); Daniel G. Nocera (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
| ABSTRACT | An optical resonator can include an optical feedback structure disposed on a substrate, and a composite including a matrix including a chromophore. The composite disposed on the substrate and in optical communication with the optical feedback structure. The chromophore can be a semiconductor nanocrystal. The resonator can provide laser emission when excited. |
| FILED | Tuesday, November 29, 2005 |
| APPL NO | 11/288321 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/67 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891720 | Rowland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark S. Rowland (Alamo, California); Neal J. Snyderman (Berkeley, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Mark S. Rowland (Alamo, California); Neal J. Snyderman (Berkeley, California) |
| ABSTRACT | A neutron detector system and method for discriminating fissile material from non-fissile material wherein a digital data acquisition unit collects data at high rate, and in real-time processes large volumes of data directly into information that a first responder can use to discriminate materials. The system comprises counting neutrons from the unknown source and detecting excess grouped neutrons to identify fission in the unknown source. Comparison of the observed neutron count distribution with a Poisson distribution is performed to distinguish fissile material from non-fissile material. |
| FILED | Wednesday, February 24, 2010 |
| APPL NO | 12/712040 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891721 | Elizondo-Decanini |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Juan M. Elizondo-Decanini (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Juan M. Elizondo-Decanini (Albuquerque, New Mexico) |
| ABSTRACT | A neutron generator is provided with a flat, rectilinear geometry and surface mounted metallizations. This construction provides scalability and ease of fabrication, and permits multiple ion source functionalities. |
| FILED | Wednesday, March 30, 2011 |
| APPL NO | 13/075817 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/191 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892478 | Bickford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Randall L. Bickford (Orangevale, California); Rahul M. Palnitkar (Lansdale, Pennsylvania) |
| ASSIGNEE(S) | Intellectual Assets LLC (Lake Tahoe, Nevada) |
| INVENTOR(S) | Randall L. Bickford (Orangevale, California); Rahul M. Palnitkar (Lansdale, Pennsylvania) |
| ABSTRACT | An adaptive model training system and method for filtering asset operating data values acquired from a monitored asset for selectively choosing asset operating data values that meet at least one predefined criterion of good data quality while rejecting asset operating data values that fail to meet at least the one predefined criterion of good data quality; and recalibrating a previously trained or calibrated model having a learned scope of normal operation of the asset by utilizing the asset operating data values that meet at least the one predefined criterion of good data quality for adjusting the learned scope of normal operation of the asset for defining a recalibrated model having the adjusted learned scope of normal operation of the asset. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 13/803436 |
| ART UNIT | 2175 — Graphical User Interface and Document Processing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 15/005 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/02 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 5/02 (20130101) G06N 5/04 (20130101) G06N 99/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892824 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dong Chen (Croton-on-Hudson, New York); Philip Heidelberger (Cortlandt Manor, New York); Sameer Kumar (White Plains, New York); Martin Ohmacht (Yorktown Heights, New York); Burkhard Steinmacher-Burow (Esslingen, Germany) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dong Chen (Croton-on-Hudson, New York); Philip Heidelberger (Cortlandt Manor, New York); Sameer Kumar (White Plains, New York); Martin Ohmacht (Yorktown Heights, New York); Burkhard Steinmacher-Burow (Esslingen, Germany) |
| ABSTRACT | A system, method and computer program product for performing various store-operate instructions in a parallel computing environment that includes a plurality of processors and at least one cache memory device. A queue in the system receives, from a processor, a store-operate instruction that specifies under which condition a cache coherence operation is to be invoked. A hardware unit in the system runs the received store-operate instruction. The hardware unit evaluates whether a result of the running the received store-operate instruction satisfies the condition. The hardware unit invokes a cache coherence operation on a cache memory address associated with the received store-operate instruction if the result satisfies the condition. Otherwise, the hardware unit does not invoke the cache coherence operation on the cache memory device. |
| FILED | Friday, January 07, 2011 |
| APPL NO | 12/986652 |
| ART UNIT | 2188 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3834 (20130101) G06F 9/30043 (20130101) G06F 9/30072 (20130101) G06F 9/30087 (20130101) G06F 12/0815 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/1225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892850 | Archer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Bob R. Cernohous (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles J. Archer (Rochester, Minnesota); Michael A. Blocksome (Rochester, Minnesota); Bob R. Cernohous (Rochester, Minnesota); Joseph D. Ratterman (Rochester, Minnesota); Brian E. Smith (Rochester, Minnesota) |
| ABSTRACT | Methods, apparatuses, and computer program products for endpoint-based parallel data processing with non-blocking collective instructions in a parallel active messaging interface (‘PAMI’) of a parallel computer are provided. Embodiments include establishing by a parallel application a data communications geometry, the geometry specifying a set of endpoints that are used in collective operations of the PAMI, including associating with the geometry a list of collective algorithms valid for use with the endpoints of the geometry. Embodiments also include registering in each endpoint in the geometry a dispatch callback function for a collective operation and executing without blocking, through a single one of the endpoints in the geometry, an instruction for the collective operation. |
| FILED | Monday, January 17, 2011 |
| APPL NO | 13/007848 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892946 | Felton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mitchell D. Felton (Rochester, Minnesota) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Mitchell D. Felton (Rochester, Minnesota) |
| ABSTRACT | Verifying speculative multithreading in an application executing in a computing system, including: executing one or more test instructions serially thereby producing a serial result, including insuring that all data dependencies among the test instructions are satisfied; executing the test instructions speculatively in a plurality of threads thereby producing a speculative result; and determining whether a speculative multithreading error exists including: comparing the serial result to the speculative result and, if the serial result does not match the speculative result, determining that a speculative multithreading error exists. |
| FILED | Thursday, December 15, 2011 |
| APPL NO | 13/326378 |
| ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/21 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892985 | Ward et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico); Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico); Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | H. Lee Ward (Albuquerque, New Mexico); Anand Ganti (Albuquerque, New Mexico); David R. Resnick (Tucson, Arizona) |
| ABSTRACT | A plurality of columns for a check matrix that implements a distance d linear error correcting code are populated by providing a set of vectors from which to populate the columns, and applying to the set of vectors a filter operation that reduces the set by eliminating therefrom all vectors that would, if used to populate the columns, prevent the check matrix from satisfying a column-wise linear independence requirement associated with check matrices of distance d linear codes. One of the vectors from the reduced set may then be selected to populate one of the columns. The filtering and selecting repeats iteratively until either all of the columns are populated or the number of currently unpopulated columns exceeds the number of vectors in the reduced set. Columns for the check matrix may be processed to reduce the amount of logic needed to implement the check matrix in circuit logic. |
| FILED | Monday, May 19, 2014 |
| APPL NO | 14/281567 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/13 (20130101) H03M 13/036 (20130101) H03M 13/132 (20130101) Original (OR) Class H03M 13/134 (20130101) H03M 13/152 (20130101) H03M 13/618 (20130101) H03M 13/6561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893150 | Faraj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Daniel A. Faraj (Rochester, Minnesota); Brian E. Smith (Knoxville, Tennessee) |
| ABSTRACT | Identifying a collective operation within an application executing on a parallel computer; identifying a call site of the collective operation; determining whether the collective operation is root-based; if the collective operation is not root-based: establishing a tuning session and executing the collective operation in the tuning session; if the collective operation is root-based, determining whether all compute nodes executing the application identified the collective operation at the same call site; if all compute nodes identified the collective operation at the same call site, establishing a tuning session and executing the collective operation in the tuning session; and if all compute nodes executing the application did not identify the collective operation at the same call site, executing the collective operation without establishing a tuning session. |
| FILED | Friday, February 15, 2013 |
| APPL NO | 13/767997 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/52 (20130101) Original (OR) Class G06F 9/546 (20130101) G06F 11/3404 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893309 | Tao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Feng Tao (Albany, California); Miquel Salmeron (Emeryville, California); Gabor A. Somorjai (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Feng Tao (Albany, California); Miquel Salmeron (Emeryville, California); Gabor A. Somorjai (Berkeley, California) |
| ABSTRACT | An embodiment of a scanning tunneling microscope (STM) reactor includes a pressure vessel, an STM assembly, and three spring coupling objects. The pressure vessel includes a sealable port, an interior, and an exterior. An embodiment of an STM system includes a vacuum chamber, an STM reactor, and three springs. The three springs couple the STM reactor to the vacuum chamber and are operable to suspend the scanning tunneling microscope reactor within the interior of the vacuum chamber during operation of the STM reactor. An embodiment of an STM assembly includes a coarse displacement arrangement, a piezoelectric fine displacement scanning tube coupled to the coarse displacement arrangement, and a receiver. The piezoelectric fine displacement scanning tube is coupled to the coarse displacement arrangement. The receiver is coupled to the piezoelectric scanning tube and is operable to receive a tip holder, and the tip holder is operable to receive a tip. |
| FILED | Tuesday, June 22, 2010 |
| APPL NO | 13/388223 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/12 (20130101) G01Q 30/16 (20130101) G01Q 60/16 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/86 (20130101) Y10S 977/861 (20130101) Y10S 977/869 (20130101) Y10S 977/871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08887652 | Berte |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frank Joseph Berte (Westford, Massachusetts) |
| ASSIGNEE(S) | Innovative Marine Technology, Inc. (Westford, Massachusetts) |
| INVENTOR(S) | Frank Joseph Berte (Westford, Massachusetts) |
| ABSTRACT | The sailing space frame of the present invention is supported by three hulls, a rudder hull a dagger board hull and an outrigger hull. The space frame also includes two mast assemblies, a fore spar, and a crew's quarters. The space frame can couple with a vessel propelled by a fossil fueled engine, and convert the combined space frame/vessel into an efficient sailing vessel that does not require fossil fuel for the trans-ocean portion of its voyage between ports. The outrigger provides sufficient stability to the sail propelled vessel so that it can carry a large enough sail area to supplant the use of the fossil fueled engine on the open ocean between ports. When entering or leaving a port the vessel uses its own engines for propulsion. |
| FILED | Wednesday, September 05, 2012 |
| APPL NO | 13/604596 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 15/0083 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888902 | Galbraith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
| ASSIGNEE(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
| INVENTOR(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
| ABSTRACT | Lightweight, small, portable devices and methods are disclosed that provide oxygen-enriched air using an ultra rapid adsorption cycle based on advanced molecular sieve materials. |
| FILED | Wednesday, August 15, 2012 |
| APPL NO | 13/586223 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/10 (20130101) Separation B01D 53/053 (20130101) Original (OR) Class B01D 53/0446 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2256/12 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889117 | Mellman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ira S. Mellman (San Francisco, California); Tarek M. Fahmy (New Haven, Connecticut); William Mark Saltzman (New Haven, Connecticut); Michael J. Caplan (Woodbridge, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Ira S. Mellman (San Francisco, California); Tarek M. Fahmy (New Haven, Connecticut); William Mark Saltzman (New Haven, Connecticut); Michael J. Caplan (Woodbridge, Connecticut) |
| ABSTRACT | Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric particle and adaptor elements which modularly couple functional elements to the particle. The modular design of these vaccine compositions, which involves flexible addition and subtraction of antigen, adjuvant, immune potentiators, molecular recognition and transport mediation elements, as well as intracellular uptake mediators, allows for exquisite control over variables that are important in optimizing an effective vaccine delivery system. |
| FILED | Friday, February 15, 2008 |
| APPL NO | 12/527143 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Original (OR) Class A61K 47/48561 (20130101) A61K 47/48892 (20130101) A61K 47/48915 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889163 | DeGrado et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William F. DeGrado (Moylan, Pennsylvania); Gregory N. Tew (Amherst, Massachusetts); Michael L. Klein (Ocean City, New York) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | William F. DeGrado (Moylan, Pennsylvania); Gregory N. Tew (Amherst, Massachusetts); Michael L. Klein (Ocean City, New York) |
| ABSTRACT | Facially amphiphilic polyphenylene and heteroarylene polymers and articles made therform having biocidal surfaces are disclosed. The polymers can inhibit the growth of microorganisms in contact with the surface or in areas adjacent to said biocidal surface. There is also disclosed a methods to attach facially amphiphilic polmers to a solid support. Utility as a contact disinfectant is disclosed. |
| FILED | Thursday, March 07, 2002 |
| APPL NO | 10/471029 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/74 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/44 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 31/16 (20130101) A61L 2300/216 (20130101) A61L 2300/404 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/2865 (20130101) C08G 18/3225 (20130101) C08G 61/02 (20130101) C08G 61/10 (20130101) C08G 61/122 (20130101) C08G 73/22 (20130101) C08G 2261/312 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889298 | Zhamu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aruna Zhamu (Centerville, Ohio); ChenGuang Liu (Fairbone, Ohio); Xiqing Wang (Cincinnati, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Aruna Zhamu (Centerville, Ohio); ChenGuang Liu (Fairbone, Ohio); Xiqing Wang (Cincinnati, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | A surface-mediated, lithium ion-exchanging energy storage device comprising: (a) A positive electrode (cathode) comprising a cathode active material that is not a functional material (bearing no functional group reactive with lithium), but having a surface area to capture or store lithium thereon; (b) A negative electrode (anode) comprising an anode active material having a surface area to capture or store lithium thereon; (c) A porous separator disposed between the two electrodes; and (d) A lithium-containing electrolyte in physical contact with the two electrodes, wherein the anode active material and/or the cathode active material has a specific surface area of no less than 100 m2/g in direct physical contact with the electrolyte to receive lithium ions therefrom or to provide lithium ions thereto; wherein at least one of the two electrodes contains therein a lithium source prior to a first charge or a first discharge cycle of the energy storage device. This new generation of energy storage device exhibits the best properties of both the lithium ion battery and the supercapacitor. |
| FILED | Tuesday, August 30, 2011 |
| APPL NO | 13/199450 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/06 (20130101) H01G 11/36 (20130101) H01G 11/56 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) Original (OR) Class H01M 4/583 (20130101) H01M 2004/021 (20130101) H01M 2004/022 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Y02E 60/122 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) Y02T 10/7022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889420 | Zang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ling Zang (Salt Lake City, Utah); Yanke Che (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Ling Zang (Salt Lake City, Utah); Yanke Che (Salt Lake City, Utah) |
| ABSTRACT | A photoconductive sensor compound for detecting explosives can have a structure I: where R is a morphology control group, A is a linking group, B is a electron donor that is selective for transferring electrons to PTCDI backbone upon irradiation to make the resulting nanostructures conductive, and R1 through R8 are side groups. |
| FILED | Thursday, December 23, 2010 |
| APPL NO | 13/518641 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Heterocyclic Compounds C07D 471/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889429 | Cao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Y. Charles Cao (Gainesville, Florida); Huimeng Wu (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Y. Charles Cao (Gainesville, Florida); Huimeng Wu (Gainesville, Florida) |
| ABSTRACT | A dual-interaction ligand for rendering otherwise hydrophobic nanoparticles water soluble or suspendable has a hydrophilic base with a plurality of hydrophilic segments extending from a core of the base, where at least one segment or the core contains a hydrophobic groups capable of forming van der Waal interaction between hydrophobic groups of the dual-interaction ligand and other hydrophobic ligands, and at least one complexing functionality to complex a metal atom or ion of a nanoparticle. The dual-interaction ligands can be combined with hydrophobic nanoparticles, where the dual-interaction ligands can displace some or all of the hydrophobic ligands of the hydrophobic nanoparticles, to form a nanoparticle-dual interaction ligand complex that can be dissolved or dispersed readily in an aqueous solution. The dual interaction ligand can be functionalized to attach an antibody or other biomolecules such that the nanoparticle dual-interaction ligands complexes can contain biomolecules. Such biomolecules modified nanoparticle dual-interaction ligands can be used for sensing, labeling, optical imaging, magnetic resonance imaging, cell separation, and treatment of diseases. |
| FILED | Wednesday, January 28, 2009 |
| APPL NO | 12/865056 |
| ART UNIT | 1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) G01N 33/54353 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889625 | Liu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shu Q. Liu (Glencoe, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Shu Q. Liu (Glencoe, Illinois) |
| ABSTRACT | The present invention provides methods, compositions, and systems for treating a subject at risk for, with, or suspected of having, myocardial ischemia using hepatocyte secretory factors (e.g., AGP2, BMPER, FGF21, NRG4, and/or TFF3) or using factors that promote liver cell migration to ischemic myocardial tissue (e.g., IL-6 and/or MMP-2). |
| FILED | Friday, July 09, 2010 |
| APPL NO | 12/833534 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/407 (20130101) A61K 35/407 (20130101) A61K 38/204 (20130101) A61K 38/204 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 38/1825 (20130101) A61K 38/1825 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889766 | Kysar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jeffrey William Kysar (New York, New York); Sanat K. Kumar (New York, New York); Benjamin Fragneaud (New York, New York); Damien Maillard (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jeffrey William Kysar (New York, New York); Sanat K. Kumar (New York, New York); Benjamin Fragneaud (New York, New York); Damien Maillard (New York, New York) |
| ABSTRACT | A method of forming a solid-state polymer can include grafting a graft polymer to nanoparticles to provide grafted nanoparticles, and dispersing the grafted nanoparticles in a polymer matrix to provide a specified loading of the grafted nanoparticles within the polymer matrix to form a solid-state polymer. A solid-state polymer can include grafted nanoparticles comprising a polymer graft grafted to nanoparticles, and a polymer matrix, in which the grafted nanoparticles are dispersed to form a solid-state polymer, the dispersion configured to provide a specified loading of the grafted nanoparticles within the solid-state polymer. |
| FILED | Thursday, March 01, 2012 |
| APPL NO | 13/410005 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 292/00 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101) C08L 25/06 (20130101) C08L 51/10 (20130101) C08L 51/10 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889908 | Madix et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. Madix (Lexington, Massachusetts); Ling Zhou (Cambridge, Massachusetts); Bingjun Xu (Cambridge, Massachusetts); Cynthia M. Friend (Lexington, Massachusetts); Cassandra G. Freyschlag (Colorado Springs, Colorado) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert J. Madix (Lexington, Massachusetts); Ling Zhou (Cambridge, Massachusetts); Bingjun Xu (Cambridge, Massachusetts); Cynthia M. Friend (Lexington, Massachusetts); Cassandra G. Freyschlag (Colorado Springs, Colorado) |
| ABSTRACT | The invention provides a method for producing amides via the reaction of aldehydes and amines with oxygen adsorbed on a metallic silver or silver alloy catalyst. An exemplary reaction is shown in Scheme 1: (I), (II), (III). |
| FILED | Tuesday, January 25, 2011 |
| APPL NO | 13/575150 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/215 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890277 | Hebard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arthur Foster Hebard (Gainesville, Florida); Sefaattin Tongay (Albany, California) |
| ASSIGNEE(S) | University of Florida Research Foundation Inc. (Gainesville, Florida) |
| INVENTOR(S) | Arthur Foster Hebard (Gainesville, Florida); Sefaattin Tongay (Albany, California) |
| ABSTRACT | Various embodiments are provided for graphite and/or graphene based semiconductor devices. In one embodiment, a semiconductor device includes a semiconductor layer and a semimetal stack. In another embodiment, the semiconductor device includes a semiconductor layer and a zero gap semiconductor layer. The semimetal stack/zero gap semiconductor layer is formed on the semiconductor layer, which forms a Schottky barrier. In another embodiment, a semiconductor device includes first and second semiconductor layers and a semimetal stack. In another embodiment, a semiconductor device includes first and second semiconductor layers and a zero gap semiconductor layer. The first semiconductor layer includes a first semiconducting material and the second semi conductor layer includes a second semiconducting material formed on the first semiconductor layer. The semimetal stack/zero gap semiconductor layer is formed on the second semiconductor layer, which forms a Schottky barrier. |
| FILED | Monday, March 14, 2011 |
| APPL NO | 13/577964 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/47 (20130101) Original (OR) Class H01L 29/475 (20130101) H01L 29/812 (20130101) H01L 29/872 (20130101) H01L 29/1606 (20130101) H01L 29/1608 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890376 | Nair et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Balakrishnan Nair (Sandy, Utah); Andrew Joseph Gill (Salt Lake City, Utah); Zachary Murphree (Salt Lake City, Utah) |
| ASSIGNEE(S) | Oscilla Power, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Balakrishnan Nair (Sandy, Utah); Andrew Joseph Gill (Salt Lake City, Utah); Zachary Murphree (Salt Lake City, Utah) |
| ABSTRACT | An apparatus harvests electrical power from mechanical energy. The apparatus includes first and second load-bearing structures, a plurality of magnetostrictive elements, and an electrical circuit or coil. The load-bearing structures experience a force from an external source. The magnetostrictive elements are arranged between the load-bearing structures. The load-bearing structures transfer at least a portion of the force to at least one of the magnetostrictive elements. In this way, at least one of the magnetostrictive elements experiences the force transferred from the load-bearing structures. The force on the magnetostrictive element causes a change in magnetic flux of the magnetostrictive element. The electrical circuit or coil is disposed within a vicinity of the magnetostrictive element which experiences the force. The electrical circuit or coil generates electric power in response to the change in the magnetic flux of the magnetostrictive element. |
| FILED | Monday, January 30, 2012 |
| APPL NO | 13/361806 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/125 (20130101) Electric Machines Not Otherwise Provided for H02N 2/186 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890618 | Pamarti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sudhakar Pamarti (Los Angeles, California); Nitesh Singhal (Los Angeles, California) |
| ABSTRACT | A zero-voltage-switching contour based outphasing power amplifier having two class-E power amplifiers connected in an out-phasing architecture coupled on opposite sides of a load being driven. The pair of class-E power amplifiers receive separate digital drive signals with an amount of phase difference that is adjusted based on the load. Variable capacitor arrays are coupled in parallel on the class-E power amplifiers and controlled in response to system parameters including duty cycle of the input signal. Efficiency of the power amplifier is maintained despite variation in output loading. |
| FILED | Thursday, January 23, 2014 |
| APPL NO | 14/162404 |
| ART UNIT | 2843 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 3/2176 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890937 | Skubic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marjorie Skubic (Columbia, Missouri); James M. Keller (Columbia, Missouri); Fang Wang (Columbia, Missouri); Derek T. Anderson (Columbia, Missouri); Erik Edward Stone (Fulton, Missouri); Robert H. Luke, III (Columbia, Missouri); Tanvi Banerjee (Columbia, Missouri); Marilyn J. Rantz (Rocheport, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Marjorie Skubic (Columbia, Missouri); James M. Keller (Columbia, Missouri); Fang Wang (Columbia, Missouri); Derek T. Anderson (Columbia, Missouri); Erik Edward Stone (Fulton, Missouri); Robert H. Luke, III (Columbia, Missouri); Tanvi Banerjee (Columbia, Missouri); Marilyn J. Rantz (Rocheport, Missouri) |
| ABSTRACT | Methods and systems for anonymized video analysis are described. In one embodiment, a first silhouette image of a person in a living unit may be accessed. The first silhouette image may be based on a first video signal recorded by a first video camera. A second silhouette image of the person in the living unit may be accessed. The second silhouette image may be of a different view of the person than the first silhouette image. The second silhouette image may be based on a second video signal recorded by a second video camera. A three-dimensional model of the person in voxel space may be generated based on the first silhouette image, the second silhouette image, and viewing conditions of the first video camera and the second video camera. In some embodiments, information on falls, gait parameters, and other movements of the person living unit are determined. Additional methods and systems are disclosed. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791496 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/021 (20130101) A61B 5/024 (20130101) A61B 5/0205 (20130101) A61B 5/0816 (20130101) A61B 5/1113 (20130101) A61B 5/1118 (20130101) A61B 5/7264 (20130101) A61B 2503/08 (20130101) A61B 2505/07 (20130101) A61B 2560/0242 (20130101) Electric Digital Data Processing G06F 19/345 (20130101) Original (OR) Class G06F 19/3487 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/0423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891247 | Prud'Homme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert K. Prud'Homme (Lawrenceville, New Jersey); Ilhan A. Aksay (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Robert K. Prud'Homme (Lawrenceville, New Jersey); Ilhan A. Aksay (Princeton, New Jersey) |
| ABSTRACT | A conductive circuit containing a polymer composite, which contains at least one polymer and a modified graphite oxide material, containing thermally exfoliated graphite oxide having a surface area of from about 300 m2/g to 2600 m2/g, and a method of making the same. |
| FILED | Thursday, March 31, 2011 |
| APPL NO | 13/077070 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/043 (20130101) Original (OR) Class C01B 31/0423 (20130101) C01B 31/0476 (20130101) C01B 2204/32 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/206 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/325 (20130101) Y02E 60/328 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891573 | Zhang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yong-Hang Zhang (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents (Scottsdale, Arizona) |
| INVENTOR(S) | Yong-Hang Zhang (Scottsdale, Arizona) |
| ABSTRACT | Use of semiconductor materials having a lattice constant of within +/−1.6% of 6.1 angstroms facilitates improved semiconductor device performance and new semiconductor structures, for example integration of field-effect devices and optoelectronic devices on a single wafer. High-mobility channels are enabled, improving device performance. |
| FILED | Monday, May 13, 2013 |
| APPL NO | 13/893232 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8252 (20130101) H01L 21/8254 (20130101) H01L 21/8258 (20130101) H01L 27/0605 (20130101) H01L 29/20 (20130101) H01L 29/22 (20130101) H01L 29/78 (20130101) H01L 29/267 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/0261 (20130101) H01S 5/323 (20130101) Original (OR) Class H01S 5/0425 (20130101) H01S 5/3009 (20130101) H01S 5/3095 (20130101) H01S 5/18361 (20130101) H01S 5/34306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891575 | Snee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Preston T. Snee (Cambridge, Massachusetts); Yin Thai Chan (Cambridge, Massachusetts); Daniel G. Nocera (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Preston T. Snee (Cambridge, Massachusetts); Yin Thai Chan (Cambridge, Massachusetts); Daniel G. Nocera (Cambridge, Massachusetts); Moungi G. Bawendi (Cambridge, Massachusetts) |
| ABSTRACT | An optical resonator can include an optical feedback structure disposed on a substrate, and a composite including a matrix including a chromophore. The composite disposed on the substrate and in optical communication with the optical feedback structure. The chromophore can be a semiconductor nanocrystal. The resonator can provide laser emission when excited. |
| FILED | Tuesday, November 29, 2005 |
| APPL NO | 11/288321 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/67 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891895 | Garrett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tim Garrett (Salt Lake City, Utah); Cale Fallgatter (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Tim Garrett (Salt Lake City, Utah); Cale Fallgatter (Salt Lake City, Utah) |
| ABSTRACT | Imaging of falling objects is described. Multiple images of a falling object can be captured substantially simultaneously using multiple cameras located at multiple angles around the falling object. An epipolar geometry of the captured images can be determined. The images can be rectified to parallelize epipolar lines of the epipolar geometry. Correspondence points between the images can be identified. At least a portion of the falling object can be digitally reconstructed using the identified correspondence points to create a digital reconstruction. |
| FILED | Thursday, December 09, 2010 |
| APPL NO | 13/514716 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/245 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/85 (20130101) G01N 2021/8592 (20130101) Meteorology G01W 1/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892198 | Bohorquez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jose L. Bohorquez (Miramar, Florida); Al-Thaddeus Avestruz (Waltham, Massachusetts); Michael D. Rinehart (Quincy, Massachusetts); Seward Rutkove (Brookline, Massachusetts); Elmer C. Lupton (Charlestown, Massachusetts) |
| ASSIGNEE(S) | Skulpt, Inc. (Davie, Florida) |
| INVENTOR(S) | Jose L. Bohorquez (Miramar, Florida); Al-Thaddeus Avestruz (Waltham, Massachusetts); Michael D. Rinehart (Quincy, Massachusetts); Seward Rutkove (Brookline, Massachusetts); Elmer C. Lupton (Charlestown, Massachusetts) |
| ABSTRACT | Embodiments of devices and methods for evaluating tissue are disclosed. In one embodiment, a method for measuring a characteristic of a tissue may include passing a current through the tissue, measuring a signal corresponding to the voltage resulting from passing the current through the tissue, analyzing current passed through the tissue and resulting voltage to determine the electrical characteristics of the tissue; and analyzing the electrical characteristics of the tissue to determine a status of the tissue. |
| FILED | Friday, April 27, 2012 |
| APPL NO | 13/823659 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/547 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08893300 | Ramachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anirudh V. Ramachandran (Atlanta, Georgia); Yogesh H. Mundada (Atlanta, Georgia); Muhammad Mukarram Bin Tariq (Atlanta, Georgia); Nicholas G. Feamster (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Anirudh V. Ramachandran (Atlanta, Georgia); Yogesh H. Mundada (Atlanta, Georgia); Muhammad Mukarram Bin Tariq (Atlanta, Georgia); Nicholas G. Feamster (Atlanta, Georgia) |
| ABSTRACT | Disclosed are embodiments of a security system for reducing data leaks by checking information flows between resources of a network. When an information flow is attempted between a sending resource, which can be anywhere in the network, and a receiving resource residing at a specific host within the network, a host labeler can determine whether information is allowed to flow from the sending resource to the receiving resource. The sending resource and the receiving resource can each have an applicable label, and each label can comprise zero, one, or more taints. For each taint having an active secrecy characteristic in a label of the sending resource, the host labeler can require that there be a matching taint with active secrecy characteristic in the receiving resource. If this condition is not met, the security system can block the information flow between the sending and receiving resources. |
| FILED | Tuesday, September 20, 2011 |
| APPL NO | 13/237618 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Information security 726/28 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08888275 | DeJong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christian Dean DeJong (Sammamish, Washington); Joshua M. Hudman (Issaquah, Washington) |
| ASSIGNEE(S) | Microvision, Inc. (Redmond, Washington) |
| INVENTOR(S) | Christian Dean DeJong (Sammamish, Washington); Joshua M. Hudman (Issaquah, Washington) |
| ABSTRACT | In imaging system (100), a spatial light modulator (101) is configured to produce images (102) by scanning a plurality light beams (104,105,106). A first optical element (107) is configured to cause the plurality of light beams to converge along an optical path (114) defined between the first optical element and the spatial light modulator. A second optical element (115) is disposed between the spatial light modulator and a waveguide (1401). The first optical element and the spatial light modulator are arranged such that an image plane (117) is created between the spatial light modulator and the second optical element. The second optical element is configured to collect the diverging light (118) from the image plane and collimate it. The second optical element then delivers the collimated light to a pupil (120) at an input of the waveguide. |
| FILED | Tuesday, May 08, 2012 |
| APPL NO | 13/466798 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) Pictorial Communication, e.g Television H04N 9/3129 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889028 | Snyder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | G. Jeffrey Snyder (Pasadena, California); Aaron LaLonde (Pasadena, California); Yanzhong Pei (Pasadena, California); Heng Wang (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | G. Jeffrey Snyder (Pasadena, California); Aaron LaLonde (Pasadena, California); Yanzhong Pei (Pasadena, California); Heng Wang (Pasadena, California) |
| ABSTRACT | The present invention demonstrates that weak scattering of carriers leads to a high mobility and therefore helps achieve low electric resistivity with high Seebeck coefficient for a thermoelectric material. The inventors demonstrate this effect by obtaining a thermoelectric figure of merit, zT, higher than 1.3 at high temperatures in n-type PbSe, because of the weak scattering of carriers in the conduction band as compared with that in the valence band. The invention further demonstrates favorable thermoelectric transport properties of n-type PbTe1-xIx with carrier concentrations ranging from 5.8×1018-1.4×1020 cm−3. |
| FILED | Thursday, May 03, 2012 |
| APPL NO | 13/463726 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2006/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/16 (20130101) Original (OR) Class H01L 35/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889295 | Yushin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York) |
| ASSIGNEE(S) | Sila Nanotechnologies, Inc. (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York) |
| ABSTRACT | Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites. |
| FILED | Tuesday, March 27, 2012 |
| APPL NO | 13/431591 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) Original (OR) Class H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/12 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889300 | Bugga et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Ratnakumar V. Bugga (Arcadia, California); William C. West (South Pasadena, California); Andrew Kindler (San Marino, California); Marshall C. Smart (Studio City, California) |
| ABSTRACT | Systems and methods in accordance with embodiments of the invention implement a lithium-based high energy density flow battery. In one embodiment, a lithium-based high energy density flow battery includes a first anodic conductive solution that includes a lithium polyaromatic hydrocarbon complex dissolved in a solvent, a second cathodic conductive solution that includes a cathodic complex dissolved in a solvent, a solid lithium ion conductor disposed so as to separate the first solution from the second solution, such that the first conductive solution, the second conductive solution, and the solid lithium ionic conductor define a circuit, where when the circuit is closed, lithium from the lithium polyaromatic hydrocarbon complex in the first conductive solution dissociates from the lithium polyaromatic hydrocarbon complex, migrates through the solid lithium ionic conductor, and associates with the cathodic complex of the second conductive solution, and a current is generated. |
| FILED | Wednesday, February 27, 2013 |
| APPL NO | 13/779435 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/231.950 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889416 | Kartalov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emil P. Kartalov (Pasadena, California); Darryl Shibata (Rolling Hills Estates, California); Clive Taylor (Malibu, California); Lawrence A. Wade (La Canada-Flintridge, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Emil P. Kartalov (Pasadena, California); Darryl Shibata (Rolling Hills Estates, California); Clive Taylor (Malibu, California); Lawrence A. Wade (La Canada-Flintridge, California) |
| ABSTRACT | Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation apparatus described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation apparatus can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation apparatus can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation apparatus can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device. Also included are methods for selectively isolating cellular material using the apparatuses described herein, as are methods for biochemical analysis of individual regions of interest of cellular material using the devices described herein. Further included are methods of making masking arrays useful for the methods described herein. |
| FILED | Thursday, January 20, 2011 |
| APPL NO | 13/010761 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891247 | Prud'Homme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert K. Prud'Homme (Lawrenceville, New Jersey); Ilhan A. Aksay (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Robert K. Prud'Homme (Lawrenceville, New Jersey); Ilhan A. Aksay (Princeton, New Jersey) |
| ABSTRACT | A conductive circuit containing a polymer composite, which contains at least one polymer and a modified graphite oxide material, containing thermally exfoliated graphite oxide having a surface area of from about 300 m2/g to 2600 m2/g, and a method of making the same. |
| FILED | Thursday, March 31, 2011 |
| APPL NO | 13/077070 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 31/043 (20130101) Original (OR) Class C01B 31/0423 (20130101) C01B 31/0476 (20130101) C01B 2204/32 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/206 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/325 (20130101) Y02E 60/328 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891895 | Garrett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tim Garrett (Salt Lake City, Utah); Cale Fallgatter (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Tim Garrett (Salt Lake City, Utah); Cale Fallgatter (Salt Lake City, Utah) |
| ABSTRACT | Imaging of falling objects is described. Multiple images of a falling object can be captured substantially simultaneously using multiple cameras located at multiple angles around the falling object. An epipolar geometry of the captured images can be determined. The images can be rectified to parallelize epipolar lines of the epipolar geometry. Correspondence points between the images can be identified. At least a portion of the falling object can be digitally reconstructed using the identified correspondence points to create a digital reconstruction. |
| FILED | Thursday, December 09, 2010 |
| APPL NO | 13/514716 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/245 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/85 (20130101) G01N 2021/8592 (20130101) Meteorology G01W 1/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892408 | Sturdza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter Sturdza (Redwood City, California); Herve Martins-Rivas (Mountain View, California); Yoshifumi Suzuki (Mountain View, California) |
| ASSIGNEE(S) | Aerion Corporation (Reno, Nevada) |
| INVENTOR(S) | Peter Sturdza (Redwood City, California); Herve Martins-Rivas (Mountain View, California); Yoshifumi Suzuki (Mountain View, California) |
| ABSTRACT | A fluid-flow simulation over a computer-generated surface is generated using a quasi-simultaneous technique. The simulation includes a fluid-flow mesh of inviscid and boundary-layer fluid cells. An initial fluid property for an inviscid fluid cell is determined using an inviscid fluid simulation that does not simulate fluid viscous effects. An initial boundary-layer fluid property a boundary-layer fluid cell is determined using the initial fluid property and a viscous fluid simulation that simulates fluid viscous effects. An updated boundary-layer fluid property is determined for the boundary-layer fluid cell using the initial fluid property, initial boundary-layer fluid property, and an interaction law. The interaction law approximates the inviscid fluid simulation using a matrix of aerodynamic influence coefficients computed using a two-dimensional surface panel technique and a fluid-property vector. An updated fluid property is determined for the inviscid fluid cell using the updated boundary-layer fluid property. |
| FILED | Wednesday, March 23, 2011 |
| APPL NO | 13/070384 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 17/5018 (20130101) Original (OR) Class G06F 2217/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08888052 | Baldwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Central Signal, LLC (Madison, Wisconsin) |
| ASSIGNEE(S) | Central Signal, LLC (Madison, Wisconsin) |
| INVENTOR(S) | David Baldwin (Madison, Wisconsin); Ahtasham Ashraf (Lewis Center, Ohio) |
| ABSTRACT | A vehicle detection system is provided for tracking, detecting, and monitoring vehicles. The system and methods of the present invention are suitable for on-track and roadway vehicles. In particular the present invention provides an improved and cost effective system and methods for tracking, detecting and monitoring locomotives and on-track vehicles. |
| FILED | Tuesday, August 20, 2013 |
| APPL NO | 13/971556 |
| ART UNIT | 3617 — Electrical Circuits and Systems |
| CURRENT CPC | Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 29/22 (20130101) B61L 29/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888902 | Galbraith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
| ASSIGNEE(S) | Separation Design Group LLC (Waynesburg, Pennsylvania) |
| INVENTOR(S) | Stephen Douglas Galbraith (Holbrook, Pennsylvania); David K. Walker (Waynesburg, Pennsylvania); Kenneth J. McGowan (Waynesburg, Pennsylvania); Elise N. DePetris (Waynesburg, Pennsylvania); Judith C. Galbraith (Holbrook, Pennsylvania) |
| ABSTRACT | Lightweight, small, portable devices and methods are disclosed that provide oxygen-enriched air using an ultra rapid adsorption cycle based on advanced molecular sieve materials. |
| FILED | Wednesday, August 15, 2012 |
| APPL NO | 13/586223 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/10 (20130101) Separation B01D 53/053 (20130101) Original (OR) Class B01D 53/0446 (20130101) B01D 53/0473 (20130101) B01D 2253/108 (20130101) B01D 2256/12 (20130101) B01D 2259/4533 (20130101) B01D 2259/4541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889065 | Chelluri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bhanumathi Chelluri (Dublin, Ohio); Edward Arlen Knoth (Beavercreek, Ohio); Edward John Schumaker (Riverside, Ohio); Ryan D. Evans (N. Canton, Ohio); James. L. Maloney, III (Canton, Ohio) |
| ASSIGNEE(S) | IAP Research, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Bhanumathi Chelluri (Dublin, Ohio); Edward Arlen Knoth (Beavercreek, Ohio); Edward John Schumaker (Riverside, Ohio); Ryan D. Evans (N. Canton, Ohio); James. L. Maloney, III (Canton, Ohio) |
| ABSTRACT | An improved sintered material and product. A nanometer size reinforcement powder is mixed with a micron size titanium or titanium alloy powder. After the reinforcement powder is generally uniformly dispersed, the powder mixture is compacted and sintered, causing the nano reinforcement to react with the titanium or titanium alloy, producing a composite material containing nano and micron size precipitates that are uniformly distributed throughout the material. |
| FILED | Thursday, September 14, 2006 |
| APPL NO | 11/531771 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0014 (20130101) B22F 3/02 (20130101) B22F 3/10 (20130101) B22F 9/04 (20130101) B22F 2009/043 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Alloys C22C 1/1084 (20130101) Original (OR) Class C22C 32/0047 (20130101) C22C 32/0084 (20130101) C22C 47/14 (20130101) C22C 49/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889295 | Yushin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York) |
| ASSIGNEE(S) | Sila Nanotechnologies, Inc. (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York) |
| ABSTRACT | Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites. |
| FILED | Tuesday, March 27, 2012 |
| APPL NO | 13/431591 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/587 (20130101) H01M 4/625 (20130101) Original (OR) Class H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/12 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889298 | Zhamu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aruna Zhamu (Centerville, Ohio); ChenGuang Liu (Fairbone, Ohio); Xiqing Wang (Cincinnati, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ASSIGNEE(S) | Nanotek Instruments, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Aruna Zhamu (Centerville, Ohio); ChenGuang Liu (Fairbone, Ohio); Xiqing Wang (Cincinnati, Ohio); Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | A surface-mediated, lithium ion-exchanging energy storage device comprising: (a) A positive electrode (cathode) comprising a cathode active material that is not a functional material (bearing no functional group reactive with lithium), but having a surface area to capture or store lithium thereon; (b) A negative electrode (anode) comprising an anode active material having a surface area to capture or store lithium thereon; (c) A porous separator disposed between the two electrodes; and (d) A lithium-containing electrolyte in physical contact with the two electrodes, wherein the anode active material and/or the cathode active material has a specific surface area of no less than 100 m2/g in direct physical contact with the electrolyte to receive lithium ions therefrom or to provide lithium ions thereto; wherein at least one of the two electrodes contains therein a lithium source prior to a first charge or a first discharge cycle of the energy storage device. This new generation of energy storage device exhibits the best properties of both the lithium ion battery and the supercapacitor. |
| FILED | Tuesday, August 30, 2011 |
| APPL NO | 13/199450 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/06 (20130101) H01G 11/36 (20130101) H01G 11/56 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) Original (OR) Class H01M 4/583 (20130101) H01M 2004/021 (20130101) H01M 2004/022 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Y02E 60/122 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) Y02T 10/7022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889377 | Kobilka |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ConfometRx, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | ConfometRx, Inc. (Palo Alto, California) |
| INVENTOR(S) | Brian Kobilka (Palo Alto, California) |
| ABSTRACT | Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising, from N-terminus to C-terminus: a) a first portion of a family C G-protein coupled receptor (GPCR), wherein the first portion comprises the TM1, TM2 and TM3, regions of the GPCR; b) a stable, folded protein insertion; and c) a second portion of the GPCR, wherein the second portion comprises the TM4, TM5 TM6 and TM7 regions of the GPCR. |
| FILED | Thursday, May 16, 2013 |
| APPL NO | 13/896115 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 14/723 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/23 (20130101) C07K 2319/24 (20130101) C07K 2319/35 (20130101) C07K 2319/43 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101) C12N 2799/026 (20130101) Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889396 | Shih |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Jason C. H. Shih (Cary, North Carolina) |
| ABSTRACT | The present invention provides methods of improving growth performance, improving the efficiency of feed utilization, increasing feed digestibility, and decreasing mortality of immature and developing animals receiving animal feed. Methods of producing a crude keratinise enzyme extract and animal feed supplements for achieving the same are also provided. |
| FILED | Wednesday, October 23, 2013 |
| APPL NO | 14/061074 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fodder A23K 1/1653 (20130101) A23K 1/1826 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892478 | Bickford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Randall L. Bickford (Orangevale, California); Rahul M. Palnitkar (Lansdale, Pennsylvania) |
| ASSIGNEE(S) | Intellectual Assets LLC (Lake Tahoe, Nevada) |
| INVENTOR(S) | Randall L. Bickford (Orangevale, California); Rahul M. Palnitkar (Lansdale, Pennsylvania) |
| ABSTRACT | An adaptive model training system and method for filtering asset operating data values acquired from a monitored asset for selectively choosing asset operating data values that meet at least one predefined criterion of good data quality while rejecting asset operating data values that fail to meet at least the one predefined criterion of good data quality; and recalibrating a previously trained or calibrated model having a learned scope of normal operation of the asset by utilizing the asset operating data values that meet at least the one predefined criterion of good data quality for adjusting the learned scope of normal operation of the asset for defining a recalibrated model having the adjusted learned scope of normal operation of the asset. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 13/803436 |
| ART UNIT | 2175 — Graphical User Interface and Document Processing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 15/005 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/02 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 5/02 (20130101) G06N 5/04 (20130101) G06N 99/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08888052 | Baldwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Central Signal, LLC (Madison, Wisconsin) |
| ASSIGNEE(S) | Central Signal, LLC (Madison, Wisconsin) |
| INVENTOR(S) | David Baldwin (Madison, Wisconsin); Ahtasham Ashraf (Lewis Center, Ohio) |
| ABSTRACT | A vehicle detection system is provided for tracking, detecting, and monitoring vehicles. The system and methods of the present invention are suitable for on-track and roadway vehicles. In particular the present invention provides an improved and cost effective system and methods for tracking, detecting and monitoring locomotives and on-track vehicles. |
| FILED | Tuesday, August 20, 2013 |
| APPL NO | 13/971556 |
| ART UNIT | 3617 — Electrical Circuits and Systems |
| CURRENT CPC | Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 29/22 (20130101) B61L 29/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889396 | Shih |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Jason C. H. Shih (Cary, North Carolina) |
| ABSTRACT | The present invention provides methods of improving growth performance, improving the efficiency of feed utilization, increasing feed digestibility, and decreasing mortality of immature and developing animals receiving animal feed. Methods of producing a crude keratinise enzyme extract and animal feed supplements for achieving the same are also provided. |
| FILED | Wednesday, October 23, 2013 |
| APPL NO | 14/061074 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fodder A23K 1/1653 (20130101) A23K 1/1826 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08889845 | Hansen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas R. Hansen (Fort Collins, Colorado); Kathleen J. Austin (Laramie, Wyoming); Alberto van Olphen (Tampa, Florida); Lea A. Rempel (Edgerton, Kansas) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Thomas R. Hansen (Fort Collins, Colorado); Kathleen J. Austin (Laramie, Wyoming); Alberto van Olphen (Tampa, Florida); Lea A. Rempel (Edgerton, Kansas) |
| ABSTRACT | Compositions and methods for the detection, diagnosis and treatment of BVDV and other viruses are provided. |
| FILED | Thursday, June 03, 2010 |
| APPL NO | 12/793092 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08889332 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Frank Y. Xu (Round Rock, Texas); Jun Sung Chun (Austin, Texas); Michael P. C. Watts (Austin, Texas) |
| ASSIGNEE(S) | Canon Nanotechnologies, Inc. (Austin, Texas); Molecular Imprints, Inc. (Austin, Texas) |
| INVENTOR(S) | Frank Y. Xu (Round Rock, Texas); Jun Sung Chun (Austin, Texas); Michael P. C. Watts (Austin, Texas) |
| ABSTRACT | A polymerizable composition includes an organic modified silicate selected from the group consisting of silsesquioxanes having the composition RSiO1.5, partially condensed alkoxysilanes, organically modified silicates having the composition RSiO3 and R2SiO2, and partially condensed orthosilicates having the composition SiOR4, where R is an organic substituent; a decomposable organic compound; a photoinitiator; and a release agent. The composition polymerizes upon exposure to UV radiation to form an inorganic silica network, and the decomposable organic compound decomposes upon exposure to heat to form pores in the inorganic silica network. The composition may be used to form a patterned dielectric layer in an integrated circuit device. A metallic film may be disposed on the patterned dielectric layer and then planarized. |
| FILED | Wednesday, June 29, 2011 |
| APPL NO | 13/172350 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/270.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890376 | Nair et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Balakrishnan Nair (Sandy, Utah); Andrew Joseph Gill (Salt Lake City, Utah); Zachary Murphree (Salt Lake City, Utah) |
| ASSIGNEE(S) | Oscilla Power, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Balakrishnan Nair (Sandy, Utah); Andrew Joseph Gill (Salt Lake City, Utah); Zachary Murphree (Salt Lake City, Utah) |
| ABSTRACT | An apparatus harvests electrical power from mechanical energy. The apparatus includes first and second load-bearing structures, a plurality of magnetostrictive elements, and an electrical circuit or coil. The load-bearing structures experience a force from an external source. The magnetostrictive elements are arranged between the load-bearing structures. The load-bearing structures transfer at least a portion of the force to at least one of the magnetostrictive elements. In this way, at least one of the magnetostrictive elements experiences the force transferred from the load-bearing structures. The force on the magnetostrictive element causes a change in magnetic flux of the magnetostrictive element. The electrical circuit or coil is disposed within a vicinity of the magnetostrictive element which experiences the force. The electrical circuit or coil generates electric power in response to the change in the magnetic flux of the magnetostrictive element. |
| FILED | Monday, January 30, 2012 |
| APPL NO | 13/361806 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/125 (20130101) Electric Machines Not Otherwise Provided for H02N 2/186 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08891583 | Forbes Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robin M. Forbes Jones (Charlotte, North Carolina); Sterry A. Shaffer (Charlotte, North Carolina) |
| ASSIGNEE(S) | ATI Properties, Inc. (Albany, Oregon) |
| INVENTOR(S) | Robin M. Forbes Jones (Charlotte, North Carolina); Sterry A. Shaffer (Charlotte, North Carolina) |
| ABSTRACT | An apparatus for casting metals by a nucleated casting technique to create a preform, the apparatus including a mold having a base and a side wall where the base can be moved relative to the side wall to withdraw the preform as it is being created. In various circumstances, portions of a droplet spray created by an atomizing nozzle, i.e., overspray, may accumulate on a top surface of the side wall and prevent or inhibit the preform from being moved relative to the side wall. The atomizing nozzle can be oriented such that the droplet spray passes over the top of the side wall to remelt and remove at least a portion of the overspray that has accumulated thereon. The mold can be rotated such that the overspray formed on a region of or on the entire perimeter of the top surface can pass through the droplet spray and can be removed from the side wall. |
| FILED | Tuesday, October 30, 2007 |
| APPL NO | 11/978923 |
| ART UNIT | 3742 — Semiconductors/Memory |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 08887572 | Turner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph A. Turner (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Joseph A. Turner (Lincoln, Nebraska) |
| ABSTRACT | A system and methods with which changes in microstructure properties such as grain size, grain elongation, texture, and porosity of materials can be determined and monitored over time to assess conditions such as stress and defects. An example system includes a number of ultrasonic transducers configured to transmit ultrasonic waves towards a target region on a specimen, a voltage source configured to excite the first and second ultrasonic transducers, and a processor configured to determine one or more properties of the specimen. |
| FILED | Tuesday, January 04, 2011 |
| APPL NO | 12/984291 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Auxiliary Equipment Specially Adapted for Railways, Not Otherwise Provided for B61K 9/08 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/12 (20130101) G01N 29/2418 (20130101) G01N 2291/102 (20130101) G01N 2291/2623 (20130101) G01N 2291/02881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08890946 | Publicover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nelson G. Publicover (Reno, Nevada); Jason Heffernan (Reno, Nevada) |
| ASSIGNEE(S) | Eyefluence, Inc. (Reno, Nevada) |
| INVENTOR(S) | Nelson G. Publicover (Reno, Nevada); Jason Heffernan (Reno, Nevada) |
| ABSTRACT | A scene illumination system is provided that produces spatially uniform or controlled brightness levels for machine vision applications. The system includes a camera, multiple light sources that preferentially illuminate different regions within the camera's field-of-view, and a processing unit coupled to the camera and light sources. Focal regions of the light sources within the camera's field-of-view are sampled to determine average regional brightness and compared to target brightness levels. The processing unit controls the light sources to increase or decrease illumination levels to converge toward the target brightness levels within the field-of-view. This modulation of the light sources may be repeated with successive video images until target brightness levels are achieved. Once achieved, the iterative feedback control may be locked-in for some applications, while for others, the iterative process may continue periodically or continuously to account for different scenes or changes in lighting conditions. |
| FILED | Monday, March 01, 2010 |
| APPL NO | 12/715177 |
| ART UNIT | 2444 — Computer Networks |
| CURRENT CPC | Television 348/78 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 08887554 | Sanchez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence James Sanchez (Ann Arbor, Michigan); Joseph McDonald (Ann Arbor, Michigan); Charles Schenk (Dexter, Michigan) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Lawrence James Sanchez (Ann Arbor, Michigan); Joseph McDonald (Ann Arbor, Michigan); Charles Schenk (Dexter, Michigan) |
| ABSTRACT | Components of interest are captured on a resin column from a sample of exhaust gas from an operating vehicle. Makeup air is added to the residual exhaust gas flow exiting the resin column at a junction downstream of the resin column. Makeup air flow rate is determined using a laminar flow element and pressure and temperature gauges associated therewith. The sample and the makeup air are drawn together through a blower and the flow rate through the blower is calculated based on differential pressure across the blower and temperature of the gas drawn through the blower. The controller adjusts a proportional control valve in the makeup air line to regulate the sample flow rate, taken as the blower flow rate minus the makeup air flow rate, at a predetermined proportion of the exhaust gas flow rate. |
| FILED | Friday, April 20, 2012 |
| APPL NO | 13/451587 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/23.310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08888994 | Kukhar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Valerii Kukhar (Kiev, Ukraine); Volodymir Kashkovski (Kiev, Ukraine); Vladislav Kyselov (Kiev, Ukraine); Yurii Besugly (Kiev, Ukraine); Yurii Kyselov (Kiev, Ukraine); Rajender Varma (Cincinnati, Ohio); Subhas Sikdar (Cincinnati, Ohio) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Valerii Kukhar (Kiev, Ukraine); Volodymir Kashkovski (Kiev, Ukraine); Vladislav Kyselov (Kiev, Ukraine); Yurii Besugly (Kiev, Ukraine); Yurii Kyselov (Kiev, Ukraine); Rajender Varma (Cincinnati, Ohio); Subhas Sikdar (Cincinnati, Ohio) |
| ABSTRACT | Method for deep desulphurization of hydrocarbon fuels includes following steps: (1) treatment of a hydrocarbon fuel under the condition of its mixing with gaseous oxidant selected from the group consisting nitrogen monoxide, dry air, ozone and a mixture of at least two of said reagents in order to oxidize sulfur-containing compounds presented in said fuel, and with a fine-dispersed adsorbent based on montmorillonite in order to adsorb oxidized sulfur-containing compounds, and (2) separation of spent adsorbent together with adsorbed oxidized sulfur-containing compounds from refined fuel. |
| FILED | Tuesday, April 19, 2011 |
| APPL NO | 13/090157 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 25/05 (20130101) C10G 27/04 (20130101) C10G 27/14 (20130101) Original (OR) Class C10G 53/08 (20130101) C10G 53/14 (20130101) C10G 2300/104 (20130101) C10G 2300/202 (20130101) C10G 2300/1044 (20130101) C10G 2300/1051 (20130101) C10G 2300/1055 (20130101) C10G 2400/02 (20130101) C10G 2400/04 (20130101) C10G 2400/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08892624 | Branson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Bradley W. Fawcett (Byron, Minnesota); Zhen Liu (Tarrytown, New York); William Waller (Laurel, Maryland); Fan Ye (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Michael J. Branson (Rochester, Minnesota); Frederick Douglis (Basking Ridge, New Jersey); Bradley W. Fawcett (Byron, Minnesota); Zhen Liu (Tarrytown, New York); William Waller (Laurel, Maryland); Fan Ye (Yorktown Heights, New York) |
| ABSTRACT | A cooperative data stream processing system is provided that utilizes a plurality of independent, autonomous and possibly heterogeneous sites in a cooperative arrangement to process user-defined job requests over dynamic, continuous streams of data. A method is provided to organize the distributed sites into a plurality of virtual organizations that can be further combined and virtualized into virtualized virtual organizations. These virtualized virtual organizations can also include additional distributed sites and existing virtualized virtual organizations and all members of a given virtualized virtual organization can share data and processing resources in order to process jobs on either a task-based or goal-based allocation mechanism. The virtualized virtual organization is created dynamically using ad-hoc collaborations among the members and is arranged in either a federated or cooperative architecture. Collaborations between members is either tightly-coupled or loosely coupled. Flexible management of resources is provided with resources being provided under exclusive control or based on best-effort access. |
| FILED | Friday, May 11, 2007 |
| APPL NO | 11/747820 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/5072 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08892704 | Bronez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas Bronez (Vienna, Virginia); Michelle Casagni (Great Falls, Virginia) |
| ASSIGNEE(S) | The Mitre Corporaton (McLean, Virginia) |
| INVENTOR(S) | Thomas Bronez (Vienna, Virginia); Michelle Casagni (Great Falls, Virginia) |
| ABSTRACT | Methods and systems for smart data processing and dissemination in wireless sensor networks are provided herein. In one aspect, the present invention provides dynamic and independent data processing and dissemination at individual sensor nodes in a wireless sensor network. In another aspect, the present invention provides data processing and/or dissemination methods at a sensor node that are responsive to, among other parameters, network traffic conditions, network connectivity conditions, conditions at the sensor node, and the data characteristics and QOS (Quality of Service) requirements of the data being processed and/or disseminated. In yet another aspect, data processing and/or dissemination rules according to the present invention are easily configurable and modifiable depending on the specific sensor networking application. |
| FILED | Friday, April 07, 2006 |
| APPL NO | 11/399387 |
| ART UNIT | 2456 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/24 (20130101) Original (OR) Class H04L 41/00 (20130101) H04L 41/12 (20130101) H04L 41/5051 (20130101) H04L 41/5077 (20130101) H04L 43/0811 (20130101) H04L 43/0852 (20130101) H04L 67/12 (20130101) Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 08891838 | Hassebrook et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Laurence G. Hassebrook (Lexington, Kentucky); Daniel L. Lau (Lexington, Kentucky); Henry G. Dietz (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laurence G. Hassebrook (Lexington, Kentucky); Daniel L. Lau (Lexington, Kentucky); Henry G. Dietz (Lexington, Kentucky) |
| ABSTRACT | A biometrics system captures and processes a handprint image using a structured light illumination to create a 2D representation equivalent of a rolled inked handprint. A processing unit calculates 3D coordinates of the hand from the plurality of images and maps the 3D coordinates to a 2D flat surface to create a 2D representation equivalent of a rolled inked handprint. |
| FILED | Sunday, August 11, 2013 |
| APPL NO | 13/964094 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2513 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00006 (20130101) G06K 9/00201 (20130101) G06K 9/2036 (20130101) G06K 2209/401 (20130101) Image Data Processing or Generation, in General G06T 7/0057 (20130101) G06T 2207/30196 (20130101) Pictorial Communication, e.g Television H04N 13/0203 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 902/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 08891766 | Kolesnikov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladimir Y. Kolesnikov (Jersey City, New Jersey) |
| ASSIGNEE(S) | Alcatel Lucent (Boulogne-Billancourt, France) |
| INVENTOR(S) | Vladimir Y. Kolesnikov (Jersey City, New Jersey) |
| ABSTRACT | Secure function evaluation SFE) with input consistency verification is performed by two parties to evaluate a function. For each execution, the first party computes a garbled circuit corresponding to the function and uses an Oblivious Transfer protocol to provide wire secrets that are an encrypted version ki of the input xi of the second party. The second party stores the encrypted version ki of the input xi of the second party for the plurality of executions. The second party receives the garbled circuit for computation of an output, which is sent to the first party. To verify the inputs of the second party for two executions, the first party computes a check garbled circuit corresponding to a verification function based on the input keys of the garbled circuits being verified; and sends the check garbled circuit to the second party for computation of a verification output. The verification output is computed by applying the stored encrypted versions ki for the two executions to the check garbled circuit. The verification output is evaluated to verify the inputs xi of the second party for the two executions. |
| FILED | Friday, September 28, 2012 |
| APPL NO | 13/630568 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/28 (20130101) Original (OR) Class H04L 9/3218 (20130101) H04L 2209/46 (20130101) H04L 2209/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 08891766 | Kolesnikov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladimir Y. Kolesnikov (Jersey City, New Jersey) |
| ASSIGNEE(S) | Alcatel Lucent (Boulogne-Billancourt, France) |
| INVENTOR(S) | Vladimir Y. Kolesnikov (Jersey City, New Jersey) |
| ABSTRACT | Secure function evaluation SFE) with input consistency verification is performed by two parties to evaluate a function. For each execution, the first party computes a garbled circuit corresponding to the function and uses an Oblivious Transfer protocol to provide wire secrets that are an encrypted version ki of the input xi of the second party. The second party stores the encrypted version ki of the input xi of the second party for the plurality of executions. The second party receives the garbled circuit for computation of an output, which is sent to the first party. To verify the inputs of the second party for two executions, the first party computes a check garbled circuit corresponding to a verification function based on the input keys of the garbled circuits being verified; and sends the check garbled circuit to the second party for computation of a verification output. The verification output is computed by applying the stored encrypted versions ki for the two executions to the check garbled circuit. The verification output is evaluated to verify the inputs xi of the second party for the two executions. |
| FILED | Friday, September 28, 2012 |
| APPL NO | 13/630568 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/28 (20130101) Original (OR) Class H04L 9/3218 (20130101) H04L 2209/46 (20130101) H04L 2209/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08891723 | Reyes, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jose N. Reyes, Jr. (Corvallis, Oregon); John T. Groome (Corvallis, Oregon); Qiao Wu (Portland, Oregon); Brian G. Woods (Corvallis, Oregon); Todd S. Palmer (Corvallis, Oregon) |
| ASSIGNEE(S) | State of Oregon Acting by and Through The State Board of Higher Education on Behalf or Oregon State University, The Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Jose N. Reyes, Jr. (Corvallis, Oregon); John T. Groome (Corvallis, Oregon); Qiao Wu (Portland, Oregon); Brian G. Woods (Corvallis, Oregon); Todd S. Palmer (Corvallis, Oregon) |
| ABSTRACT | A nuclear reactor module includes a reactor vessel containing coolant, a reactor core submerged in the coolant, and a heat exchanger configured to remove heat from the coolant. The nuclear reactor module further includes one or more heaters configured to add heat to the coolant during a startup operation and prior to the reactor core going critical. |
| FILED | Tuesday, June 10, 2008 |
| APPL NO | 12/136625 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 1/08 (20130101) Original (OR) Class G21C 15/26 (20130101) Indexing Scheme Relating to Nuclear Reactors, Power Plants and Explosives, to Protection Against Radiation, to the Treatment of Radioactively Contaminated Material, to Applications of Radioactive Sources and to the Utilisation of Cosmic Radiation G21Y 2002/207 (20130101) G21Y 2004/40 (20130101) G21Y 2004/302 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08889126 | Milbrandt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey Milbrandt (St. Louis, Missouri); Toshiyuki Araki (Tokyo, Japan); Yo Sasaki (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (Saint Louis, Missouri) |
| INVENTOR(S) | Jeffrey Milbrandt (St. Louis, Missouri); Toshiyuki Araki (Tokyo, Japan); Yo Sasaki (St. Louis, Missouri) |
| ABSTRACT | Methods of treating or preventing axonal degradation in neuropathic diseases in mammals are disclosed. The methods can comprise administering to the mammal an effective amount of an agent that acts by increasing sirtuin activity in diseased and/or injured neurons. The methods can also comprise administering to the mammal an effective amount of an agent that acts by increasing NAD activity in diseased and/or injured neurons. Also disclosed are methods of screening agents for treating a neuropathies and recombinant vectors for treating or preventing neuropathies. |
| FILED | Friday, May 28, 2010 |
| APPL NO | 12/790722 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7084 (20130101) A61K 38/45 (20130101) Original (OR) Class A61K 38/50 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 18, 2014.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2014/fedinvent-patents-20141118.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page