FedInvent™ Patents

Patent Details for Tuesday, January 13, 2015 

This page was updated on Monday, March 27, 2023 at 04:12 AM GMT

Department of Health and Human Services (HHS) 

US 08931490 Ingber et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Donald E. Ingber (Boston, Massachusetts);  Robert J. Mannix (Boston, Massachusetts);  Sanjay Kumar (Moraga, California)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Donald E. Ingber (Boston, Massachusetts);  Robert J. Mannix (Boston, Massachusetts);  Sanjay Kumar (Moraga, California)
ABSTRACT The present invention relates to signaling mechanisms that transduce magnetic inputs into physiological cellular outputs. More particularly, the present invention relates to systems and methods for non-invasively controlling cellular signaling functions and behaviors by harnessing receptor-mediated and intracellular molecular-mediated signal transduction using nanomagnetic cellular switches.
FILED Wednesday, April 09, 2008
APPL NO 12/595306
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0052 (20130101) Original (OR) Class
A61K 47/48507 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/904 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932447 Heller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael Heller (San Diego, California);  Benjamin Sullivan (San Diego, California);  Rajaram Krishnan (La Jolla, California);  Dennis Carson (La Jolla, California);  Sadik C. Esener (Solana Beach, California)
ABSTRACT Devices and techniques are described that involve a combination of multidimensional electrokinetic, dielectrophoretic, electrophoretic and fluidic forces and effects for separating cells, nanovesicles, nanoparticulates and biomarkers (DNA, RNA, antibodies, proteins) in high conductance (ionic) strength biological samples and buffers. In disclosed embodiments, a combination of continuous and/or pulsed dielectrophoretic (DEP) forces, continuous and/or pulsed field DC electrophoretic forces, microelectrophoresis and controlled fluidics are utilized with arrays of electrodes. In particular, the use of chambered DEP devices and of a properly scaled relatively larger electrode array devices that combines fluid, electrophoretic and DEP forces enables both larger and/or clinically relevant volumes of blood, serum, plasma or other samples to be more directly, rapidly and efficiently analyzed. The invention enables the creation of “seamless” sample-to-answer diagnostic systems and devices. The devices and techniques described can also carry out the assisted self-assembly of molecules, polymers, nanocomponents and mesoscale entities into three dimensional higher order structures.
FILED Friday, October 25, 2013
APPL NO 14/063884
ART UNIT 1759 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields
B03C 5/005 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/447 (20130101)
G01N 30/0005 (20130101)
G01N 33/491 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932461 Quake et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Stephen R. Quake (Stanford, California);  Joshua S. Marcus (Altadena, California);  Carl L. Hansen (Vancouver, Canada)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Stephen R. Quake (Stanford, California);  Joshua S. Marcus (Altadena, California);  Carl L. Hansen (Vancouver, Canada)
ABSTRACT Sieve valves for use in microfluidic device are provided. The valves are useful for impeding the flow of particles, such as chromatography beads or cells, in a microfluidic channel while allowing liquid solution to pass through the valve. The valves find particular use in making microfluidic chromatography modules.
FILED Tuesday, June 28, 2011
APPL NO 13/171329
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/286 (20130101) Original (OR) Class
B01J 2220/54 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 99/0001 (20130101)
F16K 99/0026 (20130101)
F16K 99/0034 (20130101)
F16K 99/0059 (20130101)
F16K 2099/008 (20130101)
F16K 2099/0074 (20130101)
F16K 2099/0084 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/603 (20130101)
G01N 30/6004 (20130101)
G01N 30/6095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932551 Kim et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dohyun Kim (Rocky Point, New York);  David Alexoff (Westhampton, New York);  Sung Won Kim (Port Jefferson, New York);  Jacob Hooker (Belmont, Massachusetts);  Richard A. Ferrieri (Patchogue, New York)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Dohyun Kim (Rocky Point, New York);  David Alexoff (Westhampton, New York);  Sung Won Kim (Port Jefferson, New York);  Jacob Hooker (Belmont, Massachusetts);  Richard A. Ferrieri (Patchogue, New York)
ABSTRACT A method for providing 11C-labeled cyanides from 11C labeled oxides in a target gas stream retrieved from an irradiated high pressure gaseous target containing O2 is provided, wherein 11C labeled oxides are reduced with H2 in the presence of a nickel catalyst under a pressure and a temperature sufficient to form a product stream comprising at least about 95% 11CH4 , the 11CH4 is then combined with an excess of NH3 in a carrier/reaction stream flowing at an accelerated velocity and the combined 11CH4 carrier/reaction stream is then contacted with a platinum (Pt) catalyst particulate supported on a substantially-chemically-nonreactive heat-stable support at a temperature of at least about 900 ° C., whereby a product stream comprising at least about 60%H11CN is provided in less than 10 minutes from retrieval of the 11C labeled oxide.
FILED Monday, August 13, 2012
APPL NO 13/584033
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Ammonia; Cyanogen; Compounds Thereof
C01C 3/0212 (20130101)
C01C 3/0216 (20130101)
C01C 3/0229 (20130101) Original (OR) Class

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932559 Hawiger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Jack J. Hawiger (Nashville, Tennessee);  Robert D. Collins (Nashville, Tennessee);  Daniel J. Moore (Nashville, Tennessee);  Jozef Zienkiewicz (Nashville, Tennessee);  Ruth Ann Veach (Brentwood, Tennessee)
ABSTRACT Nuclear Transport Modifiers such as cSN50 and cSN50.1, afford in vivo islet protection following a 2-day course of intense treatment in autoimmune diabetes-prone, non-obese diabetic (NOD) mice, a widely used model of Type 1 diabetes (T1D), which resulted in a diabetes-free state for one year without apparent toxicity and the need to use insulin. cSN50 precipitously reduces the accumulation of islet-destructive autoreactive lymphocytes while enhancing activation-induced cell death of T and B lymphocytes derived from NOD mice. cSN50 attenuated pro-inflammatory cytokine and chemokine production in immune cells in this model of human T1D. cSN50 also provides cytoprotection of beta cells, therefore preserving residual insulin-producing capacity. Because intracellular delivery of a Nuclear Transport Modifier peptide such as cSN50 and cSN50.1 can result in lowering of blood glucose levels and may reducing insulin resistance, the compositions, methods and cells described herein can also be used for treating Type 2 diabetes (T2D).
FILED Friday, October 05, 2012
APPL NO 13/645754
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932575 Stone
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Geoffrey William Stone (Coral Gables, Florida)
ASSIGNEE(S) University Of Miami (Miami, Florida)
INVENTOR(S) Geoffrey William Stone (Coral Gables, Florida)
ABSTRACT Compositions and methods of activating dendritic cells with LMP1 and LMP1-activated dendritic cell based compositions and methods are effective for dendritic cell therapy and provide an adjuvant function for vaccine administration. LMP1 or LMP1-CD40 chimeric protein may be used to activate and mature dendritic cells. LMP1 and LMP1-activated dendritic cells act as an adjuvant to enhance the cellular immune response. Also disclosed herein are kits for activating dendritic cells and for preparing a vaccine formulation. Administration of the dendritic cells transfected with LMP1 can induce an immune response against cancer or infection. The mature dendritic cells may comprise an antigen and at least one cytokine in addition to LMP1. Use of LMP1 or LMP1-CD40 provides a way to activate and mature dendritic cells that retain functional and migratory abilities without the side effects that result from maturing the dendritic cells using PGE2.
FILED Monday, September 19, 2011
APPL NO 13/825078
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/15 (20130101)
A61K 35/15 (20130101)
A61K 38/162 (20130101)
A61K 38/162 (20130101)
A61K 38/191 (20130101)
A61K 38/191 (20130101)
A61K 38/204 (20130101)
A61K 38/204 (20130101)
A61K 38/2006 (20130101)
A61K 38/2006 (20130101)
A61K 39/0011 (20130101)
A61K 39/39 (20130101)
A61K 39/245 (20130101)
A61K 45/06 (20130101)
A61K 2039/5154 (20130101)
A61K 2039/5156 (20130101)
A61K 2039/55511 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0639 (20130101) Original (OR) Class
C12N 15/85 (20130101)
C12N 2710/10043 (20130101)
C12N 2710/10071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932576 Mayfield
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Stephen P. Mayfield (Cardiff, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Stephen P. Mayfield (Cardiff, California)
ABSTRACT Methods and compositions are disclosed to engineer chloroplast comprising heterologous mammalian genes via a direct replacement of chloroplast Photosystem II (PSII) reaction center protein coding regions to achieve expression of recombinant protein above 5% of total protein. When algae is used, algal expressed protein is produced predominantly as a soluble protein where the functional activity of the peptide is intact. As the host algae is edible, production of biologics in this organism for oral delivery of proteins/peptides, especially gut active proteins, without purification is disclosed.
FILED Wednesday, January 27, 2010
APPL NO 12/695101
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932583 Mooney et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) David J. Mooney (Sudbury, Massachusetts);  Eduardo Alexandre Barros e Silva (Somerville, Massachusetts);  Elliot Earl Hill, Jr. (Ypsilanti, Missouri)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) David J. Mooney (Sudbury, Massachusetts);  Eduardo Alexandre Barros e Silva (Somerville, Massachusetts);  Elliot Earl Hill, Jr. (Ypsilanti, Missouri)
ABSTRACT A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material.
FILED Monday, November 28, 2011
APPL NO 13/305088
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/38 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/58 (20130101) Original (OR) Class
A61L 27/3633 (20130101)
A61L 2300/414 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932587 Hodin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Richard A. Hodin (Newton, Massachusetts);  Madhu S. Malo (Burlington, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Richard A. Hodin (Newton, Massachusetts);  Madhu S. Malo (Burlington, Massachusetts)
ABSTRACT This invention relates generally to a therapeutic use of alkaline phosphatase to reduce or inhibit toxic effects associated with a bacterial infection in a subject.
FILED Friday, February 11, 2011
APPL NO 13/578103
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/74 (20130101) Original (OR) Class
A61K 38/465 (20130101)

Enzymes
C12Y 301/03001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932594 Teyton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Luc Teyton (Del Mar, California);  Albert Bendelac (Chicago, Illinois);  Paul B. Savage (Mapleton, Utah)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California);  The University of Chicago (Chicago, Illinois);  Brigham Young University (Provo, Utah)
INVENTOR(S) Luc Teyton (Del Mar, California);  Albert Bendelac (Chicago, Illinois);  Paul B. Savage (Mapleton, Utah)
ABSTRACT Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune response are also disclosed. Further provided are vaccine preparations comprising NKT cell agonist compounds.
FILED Wednesday, August 04, 2010
APPL NO 12/850428
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7032 (20130101) Original (OR) Class
A61K 47/48046 (20130101)
A61K 47/48092 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932595 Iannacone et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Matteo Iannacone (Boston, Massachusetts);  Ulrich von Andrian (Chestnut Hill, Massachusetts);  Omid C. Farokhzad (Chestnut Hill, Massachusetts);  Frank Alexis (Greenville, South Carolina);  Pamela Basto (Somerville, Massachusetts);  Jinjun Shi (Boston, Massachusetts);  Elliott Ashley Moseman (Jamaica Plain, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Elena Tonti (Riccione, Italy)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Matteo Iannacone (Boston, Massachusetts);  Ulrich von Andrian (Chestnut Hill, Massachusetts);  Omid C. Farokhzad (Chestnut Hill, Massachusetts);  Frank Alexis (Greenville, South Carolina);  Pamela Basto (Somerville, Massachusetts);  Jinjun Shi (Boston, Massachusetts);  Elliott Ashley Moseman (Jamaica Plain, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Elena Tonti (Riccione, Italy)
ABSTRACT The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising nanocarriers. The present invention provides methods of designing, manufacturing, and using nanocarriers and pharmaceutical compositions thereof. For example, the present invention describes nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies.
FILED Friday, October 09, 2009
APPL NO 13/123886
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932598 Song et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) VaxInnate Corporation (Cranbury, New Jersey)
ASSIGNEE(S) VaxInnate Corporation (Cranbury, New Jersey)
INVENTOR(S) Langzhou Song (Cranbury, New Jersey);  Ge Liu (Cranbury, New Jersey);  Scott Umlauf (Cranbury, New Jersey);  Uma Kavita (Cranbury, New Jersey);  Hong Li (Cranbury, New Jersey);  Xiangyu Liu (Cranbury, New Jersey);  Bruce Weaver (Cranbury, New Jersey);  Lynda Tussey (Cranbury, New Jersey)
ABSTRACT Compositions that include a fusion protein comprising flagellin and at least one antigen that has an isoelectric point greater than about 7.0 and that is fused to at least one domain 3 of the flagellin activate Toll-like Receptor 5. Methods of stimulating an immune response, in particular, a protective immune response include administering a composition that includes an antigen fused to a loop of domain 3 of flagellin.
FILED Friday, June 28, 2013
APPL NO 13/931028
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101)
A61K 39/145 (20130101)
A61K 2039/6068 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class
C07K 14/195 (20130101)
C07K 14/255 (20130101)
C07K 2319/00 (20130101)
C07K 2319/40 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/16222 (20130101)
C12N 2760/16234 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932601 Medof et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) M. Edward Medof (Pepper Pike, Ohio);  Lisa Kuttner-Kondo (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) M. Edward Medof (Pepper Pike, Ohio);  Lisa Kuttner-Kondo (Cleveland, Ohio)
ABSTRACT A hybrid complement-regulating protein comprises a first functional unit of a first complement regulatory protein having complement regulating properties, a first spacer sequence of at least about 200 amino acids encoding a polypeptide that does not exhibit complement regulating properties and at least a second functional unit attached to the spacer sequence. The second functional unit may be a polypeptide providing a functional unit of a second complement regulatory protein, a polypeptide derived from an immunoglobulin, or a polypeptide that enhances binding of the protein to an animal cell. The hybrid protein may also contain a second spacer sequence and a third functional unit of a complement regulatory protein, a polypeptide derived from an immunoglobulin, and a polypeptide that enhances binding of the protein to an animal cell. The optional third functional unit may be the same or different from the first or second functional units.
FILED Tuesday, November 29, 2011
APPL NO 13/306631
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/70596 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932617 Elford et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Howard L. Elford (Richmond, Virginia);  Arturo J. Cardounel (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S) Howard L. Elford (Richmond, Virginia);  Arturo J. Cardounel (Gainesville, Florida)
ABSTRACT Described herein is the use of ribonucleotide reductase inhibitors in the prevention or treatment of restenosis and other vascular proliferative disorders.
FILED Friday, September 16, 2011
APPL NO 13/234852
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/625 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932808 Sarwal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Minnie M. Sarwal (Portola Valley, California);  Elaine Mansfield (Sunnyvale, California);  Sophie Brouard (Nantes, France);  Jean-Paul Soulillou (Nantes, France)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Minnie M. Sarwal (Portola Valley, California);  Elaine Mansfield (Sunnyvale, California);  Sophie Brouard (Nantes, France);  Jean-Paul Soulillou (Nantes, France)
ABSTRACT Methods are provided for determining whether a subject has a graft tolerant phenotype. In practicing the subject methods, the expression of at least one gene in a sample from the subject, e.g., a blood sample, is assayed to obtain an expression evaluation for the at least one gene. The obtained expression evaluation is then employed to determine whether the subject has a graft tolerant phenotype. Also provides are compositions, systems and kits that find use in practicing the subject methods. The methods and compositions find use in a variety of applications, including the determination of an immunosuppressive therapy regimen.
FILED Thursday, January 20, 2005
APPL NO 10/585610
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932814 Cong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Le Cong (Cambridge, Massachusetts);  Feng Zhang (Cambridge, Massachusetts)
ABSTRACT The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR/Cas system.
FILED Tuesday, April 22, 2014
APPL NO 14/258458
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932828 Rosendahl et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Mary S. Rosendahl (Broomfield, Colorado);  George N. Cox (Louisville, Colorado);  Daniel H. Doherty (Boulder, Colorado)
ASSIGNEE(S) Bolder Biotechnology, Inc. (Boulder, Colorado)
INVENTOR(S) Mary S. Rosendahl (Broomfield, Colorado);  George N. Cox (Louisville, Colorado);  Daniel H. Doherty (Boulder, Colorado)
ABSTRACT The present invention relates to novel methods for making and refolding insoluble or aggregated proteins having free cysteines in which a host cell expressing the protein is exposed to a cysteine blocking agent. The soluble, refolded proteins produced by the novel methods can then be modified to increase their effectiveness. Such modifications include attaching a PEG moiety to form PEGylated proteins.
FILED Wednesday, September 29, 2010
APPL NO 12/893764
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48215 (20130101)

Peptides
C07K 1/1133 (20130101)
C07K 14/52 (20130101) Original (OR) Class
C07K 14/56 (20130101)
C07K 14/61 (20130101)
C07K 14/78 (20130101)
C07K 14/505 (20130101)
C07K 14/515 (20130101)
C07K 14/535 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932842 Silverman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Richard B. Silverman (Northbrook, Illinois);  Fengtian Xue (Baton Rouge, Louisiana);  He Huang (Chicago, Illinois)
ABSTRACT Nitric oxide synthase (NOS) inhibitor compounds comprising bi-terminal aromatic ring moieties, and related methods of NOS inhibition.
FILED Monday, October 01, 2012
APPL NO 13/573654
ART UNIT 1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Heterocyclic Compounds
C07D 401/10 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 401/14 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0075 (20130101)

Enzymes
C12Y 114/13039 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932846 Horwitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Marcus A. Horwitz (Los Angeles, California);  Michael V. Tullius (Encino, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Marcus A. Horwitz (Los Angeles, California);  Michael V. Tullius (Encino, California)
ABSTRACT Recombinant immunogenic compositions, and methods for the manufacture and use, are provided for the prevention and treatment of intracellular pathogen diseases in humans and animals. The recombinant immunogenic compositions express high levels of recombinant proteins in vectors that do not harbor an antibiotic resistance marker (“unmarked”).
FILED Thursday, June 12, 2008
APPL NO 12/664485
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/04 (20130101) Original (OR) Class
A61K 2039/523 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932856 Jaenisch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Rudolf Jaenisch (Brookline, Massachusetts);  Konrad Hochedlinger (Cambridge, Massachusetts)
ABSTRACT The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
FILED Friday, October 05, 2012
APPL NO 13/646444
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0273 (20130101)
A01K 67/0275 (20130101)
A01K 2217/05 (20130101)
A01K 2227/105 (20130101)

Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0696 (20130101)
C12N 15/85 (20130101) Original (OR) Class
C12N 15/8509 (20130101)
C12N 15/8775 (20130101)
C12N 2830/003 (20130101)
C12N 2830/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932859 Tsien et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Roger Y. Tsien (La Jolla, California);  Lei Wang (San Diego, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Roger Y. Tsien (La Jolla, California);  Lei Wang (San Diego, California)
ABSTRACT Methods using somatic hypermutation (SHM) for producing polypeptide and nucleic acid variants, and nucleic acids encoding such polypeptide variants are disclosed. Such variants may have desired properties. Also disclosed are novel polypeptides, such as improved fluorescent proteins, produced by the novel methods, and nucleic acids, vectors, and host cells comprising such vectors.
FILED Wednesday, May 21, 2008
APPL NO 12/124888
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932876 Cutler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Cathy Sue Cutler (Columbia, Missouri);  Gary John Ehrhardt (Columbia, Missouri);  Hendrik Petrus Engelbrecht (Columbia, Missouri);  Delbert E. Day (Rolla, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Cathy Sue Cutler (Columbia, Missouri);  Gary John Ehrhardt (Columbia, Missouri);  Hendrik Petrus Engelbrecht (Columbia, Missouri);  Delbert E. Day (Rolla, Missouri)
ABSTRACT The present invention provides a simple and inexpensive method for removing metal and other impurities in a radioisotope solution. The invention further includes the development of a new parent/daughter generator system for collecting the daughter isotope in a concentrated solution.
FILED Monday, May 11, 2009
APPL NO 12/454003
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/00 (20130101)

Separation
B01D 15/362 (20130101)
B01D 15/363 (20130101)

Conversion of Chemical Elements; Radioactive Sources
G21G 1/0005 (20130101) Original (OR) Class
G21G 4/08 (20130101)

Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation
G21H 5/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933032 Whitsett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Jeffrey A. Whitsett (Cincinnati, Ohio);  Machiko Ikegami (Cincinnati, Ohio)
ASSIGNEE(S) Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S) Jeffrey A. Whitsett (Cincinnati, Ohio);  Machiko Ikegami (Cincinnati, Ohio)
ABSTRACT Surfactant protein D (SP-D) is a 43-kDa member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells of the lung. Described herein are methods and compositions for the treatment of disorders associated with lung injury, including methods and compositions for the treatment of bronchopulmonary disorder (BPD) using recombinant human surfactant protein D and surfactant formulations.
FILED Friday, February 04, 2011
APPL NO 13/021629
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/12 (20130101) Original (OR) Class
A61K 38/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933041 Panicali et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Dennis L. Panicali (Acton, Massachusetts);  Gail P. Mazzara (Winchester, Massachusetts);  Linda R. Gritz (Somerville, Massachusetts);  Jeffrey Schlom (Potomac, Maryland);  Kwong-Yok Tsang (Bethesda, Maryland);  James W. Hodge (Gaithersberg, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dennis L. Panicali (Acton, Massachusetts);  Gail P. Mazzara (Winchester, Massachusetts);  Linda R. Gritz (Somerville, Massachusetts);  Jeffrey Schlom (Potomac, Maryland);  Kwong-Yok Tsang (Bethesda, Maryland);  James W. Hodge (Gaithersberg, Maryland)
ABSTRACT The present invention is directed to a system for treating individuals at risk of or suffering from breast cancer. The system comprises administering to the individual a recombinant poxvirus, where the poxvirus contains in a foreign nucleic acid encoding at least one breast cancer antigen.
FILED Friday, November 12, 2004
APPL NO 10/579007
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 48/005 (20130101)
A61K 2039/53 (20130101)
A61K 2039/545 (20130101)
A61K 2039/55522 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2710/24043 (20130101)
C12N 2710/24071 (20130101)
C12N 2710/24143 (20130101)
C12N 2710/24171 (20130101)
C12N 2799/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933043 Takagi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Masatoshi Takagi (Tokyo, Japan);  Michael B. Kastan (Cordova, Tennessee)
ASSIGNEE(S) St. Jude Children's Research Hospital (Memphis, Tennessee)
INVENTOR(S) Masatoshi Takagi (Tokyo, Japan);  Michael B. Kastan (Cordova, Tennessee)
ABSTRACT The present invention relates to novel methods for modulating the activity of p53 tumor suppressor protein by affecting p53 translational regulation. More specifically, the invention relates to novel methods for modulating p53 mRNA translation in a cell by affecting a function of a p53 5′-untranslated region (5′UTR), including its interaction with proteins such as Ribosomal Protein L26 (RPL26), nucleolin, and p53. The invention also relates to the use of these methods for treating cancer, neurodegenerative disorders and minimizing the negative effects of cellular stresses.
FILED Thursday, September 28, 2006
APPL NO 12/063463
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1135 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/12 (20130101)
C12N 2310/14 (20130101)
C12N 2310/15 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933065 Kohn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Harold L. Kohn (Chapel Hill, North Carolina);  Christophe Salomé (Herrlisheim-prés-Colmar, France);  Ki Duk Park (Cary, North Carolina);  Elise Salomé-Grosjean (Herrlisheim-prés-Colmar, France)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Harold L. Kohn (Chapel Hill, North Carolina);  Christophe Salomé (Herrlisheim-prés-Colmar, France);  Ki Duk Park (Cary, North Carolina);  Elise Salomé-Grosjean (Herrlisheim-prés-Colmar, France)
ABSTRACT A first aspect of the invention is a compound (sometimes also referred to herein as an “active agent” or “active compound”) of Formula I or Ia:
or a pharmaceutically acceptable salt or prodrug thereof. Compositions thereof and methods of using the same (e.g. for the treatment of a neurological disease) are also described.
FILED Friday, September 17, 2010
APPL NO 12/884963
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 233/18 (20130101)
C07C 235/08 (20130101)

Heterocyclic Compounds
C07D 213/40 (20130101) Original (OR) Class
C07D 213/56 (20130101)
C07D 229/00 (20130101)
C07D 277/30 (20130101)
C07D 307/68 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933075 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Guoxin Wang (Shenzhen, China PRC);  Ming Luo (Vestavia Hills, Alabama);  Zhen Yang (Shenzhen, China PRC)
ASSIGNEE(S) FUZIANS BIOMEDICALS, Inc. (George Town, Grand Cayman, Cayman Islands);  The UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S) Guoxin Wang (Shenzhen, China PRC);  Ming Luo (Vestavia Hills, Alabama);  Zhen Yang (Shenzhen, China PRC)
ABSTRACT Novel 3-N-cycloalkyl-5-substituted-2-thioxothiazolidin-4-one derivatives that are effective for use in treating viral infections are described. Also described are pharmaceutical compositions comprising the 3-N-cycloalkyl-5-substituted-2-thioxothiazolidin-4-one derivatives and methods for using the compounds or compositions.
FILED Friday, June 17, 2011
APPL NO 13/703383
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 417/06 (20130101)
C07D 417/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933076 Watterson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) D. Martin Watterson (Chicago, Illinois);  Linda Van Eldik (Chicago, Illinois);  Jacques Haiech (Strasbourg, France);  Marcel Hibert (Eschau, France);  Jean-Jacques Bourguignon (Illkirch, France);  Anastasia Velentza (San Diego, California);  Wenhui Hu (Guangzhou, China PRC);  Magdalena Zasadzki (Chicago, Illinois)
ASSIGNEE(S) Centre National de la Recherche Scientifique (CNRS) (Paris, France);  Northwestern University (Evanston, Illinois);  Universite de Strasbourg (Strasbourg, France)
INVENTOR(S) D. Martin Watterson (Chicago, Illinois);  Linda Van Eldik (Chicago, Illinois);  Jacques Haiech (Strasbourg, France);  Marcel Hibert (Eschau, France);  Jean-Jacques Bourguignon (Illkirch, France);  Anastasia Velentza (San Diego, California);  Wenhui Hu (Guangzhou, China PRC);  Magdalena Zasadzki (Chicago, Illinois)
ABSTRACT The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for, research, drug screening, and therapeutic applications.
FILED Friday, June 08, 2012
APPL NO 13/491986
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/247
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933082 Clapp et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) D Wade Clapp (Indianapolis, Indiana);  David Ingram (Indianapolis, Indiana);  Feng-Chun Yang (Carmel, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corp. (Indianapolis, Indiana)
INVENTOR(S) D Wade Clapp (Indianapolis, Indiana);  David Ingram (Indianapolis, Indiana);  Feng-Chun Yang (Carmel, Indiana)
ABSTRACT Germline mutations in the NF1 tumor suppressor gene cause Von Recklinghausen's neurofibromatosis type 1 (NF1), a common genetic disorder of the nervous system characterized by plexiform neurofibroma development. Using adoptive transfer of hematopoietic cells, we establish that NF1 heterozygosity of bone marrow derived cells in the tumor microenvironment is sufficient to allow neurofibroma progression in the context of Schwann cell nullizygosity. Further, genetic or pharmacologic attenuation of the c-kit signaling pathway in hematopoietic cells greatly diminishes neurofibroma initiation and progression. These studies identify haploinsufficient hematopoietic cells and the c-kit receptor as therapeutic targets for preventing plexiform neurofibromas and implicate mast cells as critical mediators of tumor initiation. Administering therapeutically effective doses of a tyrosine kinase inhibitor such as the compound imatinib mesylate to a patient in need thereof to treat tumors in a human patient afflicted with plexiform neurofibroma.
FILED Friday, September 20, 2013
APPL NO 14/032994
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/255.50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933087 Finley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Daniel J. Finley (Jamaica Plain, Massachusetts);  Randall W. King (Brookline, Massachusetts);  Byung-Hoon Lee (Cambridge, Massachusetts);  Min J. Lee (Jamaica Plain, Massachusetts);  Timothy C. Gahman (Encinitas, California)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Daniel J. Finley (Jamaica Plain, Massachusetts);  Randall W. King (Brookline, Massachusetts);  Byung-Hoon Lee (Cambridge, Massachusetts);  Min J. Lee (Jamaica Plain, Massachusetts);  Timothy C. Gahman (Encinitas, California)
ABSTRACT Proteinopathies result from the proteasome not acting efficiently enough to eliminate harmful proteins and prevent the formation of the pathogenic aggregates. As described herein, inhibition of proteasome-associated deubiquitinase Usp14 results in increased proteasome efficiency. The present invention therefore provides novel compositions and methods for inhibition of Usp14, enhancement of proteasome activity and treatment of proteinopathies.
FILED Friday, July 22, 2011
APPL NO 13/811129
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 487/04 (20130101)
C07D 495/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933129 Abramson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. State Government
State of Oregon
APPLICANT(S) Jonathan Abramson (Portland, Oregon);  Robert Strongin (Portland, Oregon)
ASSIGNEE(S) State of Oregon by and through the State Board of Higher Education on behalf of Portland State University (Portland, Oregon)
INVENTOR(S) Jonathan Abramson (Portland, Oregon);  Robert Strongin (Portland, Oregon)
ABSTRACT The present teachings provide compounds of Formulae I and II: and pharmaceutically acceptable salts, hydrates, complexes, esters, and prodrugs thereof, wherein R1, R1′, R2, R2′, R3, R3′, and X are as defined herein. The present teachings also provide methods of making the compounds of formulae I and II, and methods of treating RyR-associated conditions, disorders, and diseases that include administering a therapeutically effective amount of a compound of formula I or II to a subject in need thereof. In addition, the present teachings relate to methods of reducing the open probability of a ryanodine receptor, and methods of reducing Ca2+ release across a ryanodine receptor (e.g., into the cytoplasm of a cell), by contacting a compound of formula I or II with a ryanodine receptor.
FILED Thursday, April 15, 2010
APPL NO 13/264055
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/554 (20130101)

Heterocyclic Compounds
C07D 417/06 (20130101) Original (OR) Class
C07D 417/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933143 Boydston et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Andrew J. Boydston (Seattle, Washington);  Robert H. Grubbs (South Pasadena, California);  Chris Daeffler (Pasadena, California);  Nebojsa Momcilovic (Pasadena, California)
ABSTRACT Compositions and methods for adjustable lenses are provided. In some embodiments, the lenses contain a lens matrix material, a masking compound, and a prepolymer. The lens matrix material provides structure to the lens. The masking compound is capable of blocking polymerization or crosslinking of the prepolymer, until photoisomerization of the compound is triggered, and the compound is converted from a first isomer to a second isomer having a different absorption profile. The prepolymer is a composition that can undergo a polymerization or crosslinking reaction upon photoinitiation to alter one or more of the properties of the lenses.
FILED Tuesday, November 05, 2013
APPL NO 14/071947
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/14 (20130101)
A61F 2/1624 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0051 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 22/14 (20130101)
C08F 120/14 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/38 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/24 (20130101)
C08J 3/28 (20130101)
C08J 2333/00 (20130101)

Compositions of Macromolecular Compounds
C08L 33/08 (20130101)
C08L 33/10 (20130101)
C08L 83/04 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/043 (20130101)
G02B 1/043 (20130101)
G02B 1/043 (20130101)
G02B 1/043 (20130101)

Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses
G02C 7/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933197 Stemmer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Willem P. Stemmer (Los Gatos, California);  Volker Schellenberger (Palo Alto, California)
ASSIGNEE(S) Amunix Operating Inc. (Mountain View, California)
INVENTOR(S) Willem P. Stemmer (Los Gatos, California);  Volker Schellenberger (Palo Alto, California)
ABSTRACT The present invention relates to biologically active polypeptides linked to one or more accessory polypeptides. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.
FILED Friday, August 15, 2008
APPL NO 12/228859
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933201 McKee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Patrick A. McKee (Oklahoma City, Oklahoma);  Kenneth W. Jackson (Edmond, Oklahoma);  Kyung N. Lee (Oklahoma City, Oklahoma);  Victoria J. Christiansen (Oklamhoma City, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Patrick A. McKee (Oklahoma City, Oklahoma);  Kenneth W. Jackson (Edmond, Oklahoma);  Kyung N. Lee (Oklahoma City, Oklahoma);  Victoria J. Christiansen (Oklamhoma City, Oklahoma)
ABSTRACT The presently disclosed and claimed inventive concepts include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and α2-antiplasmin and abnormal cell proliferation. The presently disclosed and claimed inventive concepts also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed and claimed inventive concepts further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma α2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers.
FILED Wednesday, December 15, 2010
APPL NO 12/969161
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/8121 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933210 Lu et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Yi Lu (Champaign, Illinois);  Yu Xiang (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Yi Lu (Champaign, Illinois);  Yu Xiang (Urbana, Illinois)
ABSTRACT A general methodology to design label-free fluorescent functional nucleic acid sensors using a vacant site approach and an abasic site approach is described. In one example, a method for designing label-free fluorescent functional nucleic acid sensors (e.g., those that include a DNAzyme, aptamer or aptazyme) that have a tunable dynamic range through the introduction of an abasic site (e.g., dSpacer) or a vacant site into the functional nucleic acids. Also provided is a general method for designing label-free fluorescent aptamer sensors based on the regulation of malachite green (MG) fluorescence. A general method for designing label-free fluorescent catalytic and molecular beacons (CAMBs) is also provided. The methods demonstrated here can be used to design many other label-free fluorescent sensors to detect a wide range of analytes. Sensors and methods of using the disclosed sensors are also provided.
FILED Thursday, October 06, 2011
APPL NO 13/267414
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933270 Serhan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Charles N. Serhan (Needham, Massachusetts);  Bruce D. Levy (West Roxbury, Massachusetts)
ABSTRACT The present invention is generally drawn to novel isolated therapeutic agents, termed resolvins, generated from the interaction between a dietary omega-3 polyunsaturated fatty acid (PUFA) such as eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA), cyclooxygenase-II (COX-2) and an analgesic, such as aspirin (ASA). Surprisingly, careful isolation of compounds generated from the combination of components in an appropriate environment provide di- and tri-hydroxy EPA or DHA compounds having unique structural and physiological properties. The present invention therefore provides for many new useful therapeutic di- or tri-hydroxy derivatives of EPA or DHA (resolvins) that diminish, prevent, or eliminate inflammation or PMN migration, for example. The present invention also provides methods of use, methods of preparation, and packaged pharmaceuticals for use as medicaments for the compounds disclosed throughout the specification.
FILED Monday, October 28, 2013
APPL NO 14/064803
ART UNIT 1671 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/202 (20130101)
A61K 31/275 (20130101)
A61K 31/445 (20130101)
A61K 31/495 (20130101)
A61K 31/537 (20130101)
A61K 31/551 (20130101)
A61K 31/655 (20130101)

Acyclic or Carbocyclic Compounds
C07C 59/42 (20130101) Original (OR) Class
C07C 59/48 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/1868 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933384 Savran et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Cagri A. Savran (West Lafayette, Indiana);  Khalid M. Arif (Lahore, Pakistan)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Cagri A. Savran (West Lafayette, Indiana);  Khalid M. Arif (Lahore, Pakistan)
ABSTRACT A system for and method of performing multi-technique imaging. Such multi-technique imaging system includes a surface for supporting a specimen and at least two illumination sources for producing light radiation. The system also includes a plurality of reflective and refractive devices arranged to direct at least part of the light radiation from each of the at least two illumination sources to the surface such that at least part of the light radiation from each of the at least two illumination sources illuminates substantially the same area on the surface. The system also includes a sensor configured to receive light radiation from the at least two illumination sources reflected by the specimen and/or that pass by the specimen. The system also includes a power source configured to power the at least two illumination sources and the sensor.
FILED Monday, March 26, 2012
APPL NO 13/430316
ART UNIT 2878 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/55 (20130101) Original (OR) Class
G01N 21/65 (20130101)
G01N 21/553 (20130101)
G01N 21/554 (20130101)
G01N 21/4788 (20130101)
G01N 21/6456 (20130101)
G01N 2021/479 (20130101)
G01N 2021/558 (20130101)
G01N 2201/0221 (20130101)
G01N 2201/0693 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/0008 (20130101)
G02B 21/18 (20130101)
G02B 21/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933698 Corum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Regents of the University of Minnesota (St. Paul, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Curtis A. Corum (Shoreview, Minnesota);  Djaudat S. Idiyatullin (New Brighton, Minnesota);  Steen Moeller (Golden Valley, Minnesota);  Michael G. Garwood (Medina, Minnesota)
ABSTRACT A magnetic resonance image is produced by shifting a gap during acquisition of spin data for a specimen. The spin data is generated by a gapped excitation sequence.
FILED Wednesday, August 07, 2013
APPL NO 13/961042
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/54 (20130101) Original (OR) Class
G01R 33/565 (20130101)
G01R 33/4641 (20130101)
G01R 33/4816 (20130101)
G01R 33/4824 (20130101)
G01R 33/56509 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934698 Wirtz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Denis Gaston Wirtz (Washington, District of Columbia);  Pei-Hsun Wu (Towson, Maryland);  Shyam Bharat Khatau (Baltimore, Maryland);  Wei-Chiang Chen (Baltimore, Maryland);  Jude Marvin George Phillip, Jr. (Washington, District of Columbia);  Zev Ari Binder (Baltimore, Maryland);  Yiider Tseng (Gainesville, Florida)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  University of Florida (Gainesville, Florida)
INVENTOR(S) Denis Gaston Wirtz (Washington, District of Columbia);  Pei-Hsun Wu (Towson, Maryland);  Shyam Bharat Khatau (Baltimore, Maryland);  Wei-Chiang Chen (Baltimore, Maryland);  Jude Marvin George Phillip, Jr. (Washington, District of Columbia);  Zev Ari Binder (Baltimore, Maryland);  Yiider Tseng (Gainesville, Florida)
ABSTRACT A diagnostic device includes a microscope configured to obtain image data on a plurality of cells and a computing device. The computing device is configured to receive the image data, identify at least a portion of each of the plurality of cells based on the received image data, determine at least one of a value of a morphological parameter for each identified at least a portion of the plurality of cells or a relative organization among the identified at least a portion of the plurality of cells, and calculate statistics for the plurality of cells based on the at least one of the determined values of the morphological parameter or the determined relative organization, the statistics including information suitable for distinguishing metastatic cells from non-metastatic cells. The diagnostic device further includes an output device configured to output the statistics for diagnosis.
FILED Friday, June 22, 2012
APPL NO 13/530772
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/38 (20130101)
G06K 9/00127 (20130101) Original (OR) Class
G06K 9/00134 (20130101)
G06K 9/00147 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/30024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934965 Rogers et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
APPLICANT(S) John Rogers (Champaign, Illinois);  Dae-Hyeong Kim (Champaign, Illinois);  Brian Litt (Bala Cynwyd, Pennsylvania);  Jonathan Viventi (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) John Rogers (Champaign, Illinois);  Dae-Hyeong Kim (Champaign, Illinois);  Brian Litt (Bala Cynwyd, Pennsylvania);  Jonathan Viventi (Philadelphia, Pennsylvania)
ABSTRACT Provided are methods and devices for interfacing with brain tissue, specifically for monitoring and/or actuation of spatio-temporal electrical waveforms. The device is conformable having a high electrode density and high spatial and temporal resolution. A conformable substrate supports a conformable electronic circuit and a barrier layer. Electrodes are positioned to provide electrical contact with a brain tissue. A controller monitors or actuates the electrodes, thereby interfacing with the brain tissue. In an aspect, methods are provided to monitor or actuate spatio-temporal electrical waveform over large brain surface areas by any of the devices disclosed herein.
FILED Friday, June 01, 2012
APPL NO 13/486726
ART UNIT 3739 — Optical Communications
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0478 (20130101) Original (OR) Class
A61B 5/04001 (20130101)
A61B 5/4094 (20130101)
A61B 5/6868 (20130101)
A61B 2562/046 (20130101)
A61B 2562/125 (20130101)
A61B 2562/164 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/20 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0531 (20130101)
A61N 1/3606 (20130101)
A61N 1/36017 (20130101)
A61N 1/36025 (20130101)
A61N 5/0601 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935189 Tyson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Interior (DOI)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Mabry W. Tyson (Los Altos, California);  Douglas E. Appelt (Palo Alto, California);  Min Yin (San Jose, California);  William Jarrold (Davis, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Mabry W. Tyson (Los Altos, California);  Douglas E. Appelt (Palo Alto, California);  Min Yin (San Jose, California);  William Jarrold (Davis, California)
ABSTRACT A non-transitory computer readable storage medium includes instructions to collect explicit feedback from a user regarding user content preferences. Multiple data sources are monitored. Topics associated with the multiple data sources are classified. The importance of the topics to the user is characterized. Content is delivered to the user when a selected topic exceeds an importance threshold for the user. Implicit feedback from the user that characterizes refined user content preferences is tracked. The instructions to characterize the importance of topics evaluates the explicit feedback and the implicit feedback.
FILED Friday, May 27, 2011
APPL NO 13/118226
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/30997 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 30/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 08931114 Martin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Brett D. Martin (Washington, District of Columbia);  Martin H. Moore (Woodbridge, Virginia);  Banahalli R. Ratna (Alexandria, Virginia);  Gusphyl Justin (St. Louis, Missouri);  Jawad Naciri (Herndon, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brett D. Martin (Washington, District of Columbia);  Martin H. Moore (Woodbridge, Virginia);  Banahalli R. Ratna (Alexandria, Virginia);  Gusphyl Justin (St. Louis, Missouri);  Jawad Naciri (Herndon, Virginia)
ABSTRACT A redox-active conductive polymer includes a charged tether. An interpenetrating network including such a conducting polymer can be switched between two states of diffusivity (porosity) by application of a voltage. Such a material can be useful in breathable protective clothing, controlled release, intelligent sensing/filtration, novel separation processes, nanomanufacturing, and other areas.
FILED Tuesday, November 15, 2011
APPL NO 13/296920
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 333/38 (20130101) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/126 (20130101)
C08G 65/3324 (20130101)
C08G 65/3344 (20130101)
C08G 65/3346 (20130101)
C08G 65/3348 (20130101)
C08G 2261/44 (20130101)
C08G 2261/135 (20130101)
C08G 2261/147 (20130101)
C08G 2261/516 (20130101)
C08G 2261/1424 (20130101)
C08G 2261/1426 (20130101)
C08G 2261/1432 (20130101)
C08G 2261/1452 (20130101)
C08G 2650/50 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931225 Fifield et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
APPLICANT(S) John Fifield (Buckinghamshire, United Kingdom);  Leonard Browning (Aurora, Illinois)
ASSIGNEE(S) Oldcastle APG, Inc. (Atlanta, Georgia)
INVENTOR(S) John Fifield (Buckinghamshire, United Kingdom);  Leonard Browning (Aurora, Illinois)
ABSTRACT A cladding system for cladding a supporting wall is disclosed. The cladding system includes a plurality of building blocks, each having a body and a facing; and a plurality of support brackets for mounting the blocks on the supporting wall in a plurality of adjoining horizontal rows. The body of each block includes engagement means for engaging at least one of the support brackets such that, in use, at least a part of the body of each block abuts at least a part of the body of a neighbouring block in an adjoining row so as to guard against water penetration between the rows.
FILED Friday, May 21, 2010
APPL NO 13/321671
ART UNIT 3638 — Static Structures, Supports and Furniture
CURRENT CPC
Finishing Work on Buildings, e.g Stairs, Floors
E04F 13/0803 (20130101) Original (OR) Class
E04F 13/0826 (20130101)
E04F 2201/035 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931281 Ruberte Sanchez et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Jose E. Ruberte Sanchez (Jupiter, Florida);  David C. Schuppert (Tequesta, Florida)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Jose E. Ruberte Sanchez (Jupiter, Florida);  David C. Schuppert (Tequesta, Florida)
ABSTRACT An external flap connection assembly for a turbine engine nozzle has a track frame, a slider track, and an external flap. The external flap is removably connected to the slider track via a retaining member which has a slider block.
FILED Monday, June 07, 2010
APPL NO 12/794816
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 1/12 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2250/40 (20130101)
F05D 2260/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931414 Boswell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Christopher Boswell (Hayattesville, Maryland);  Carl Gotzmer (Accokeek, Maryland);  Steven Kim (Crofton, Maryland);  Steve Dunham (Alexandria, Virginia);  Michael Dunn (La Plata, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Christopher Boswell (Hayattesville, Maryland);  Carl Gotzmer (Accokeek, Maryland);  Steven Kim (Crofton, Maryland);  Steve Dunham (Alexandria, Virginia);  Michael Dunn (La Plata, Maryland)
ABSTRACT A reaction container has contains an amount of a water reactive material and a volume of water within the confined space of its interior. The water reactive material, which contains aluminum, is formed as two separate and spaced apart portions. The water is located between the two portions of the water reactive material. A detonation mechanism, which is configured to mix the amount of water reactive material and the volume of water, is provided in communication with each portion of the water reactive material. The volume of water and the aluminum in the water reactive material are stoichiometrically balanced.
FILED Wednesday, February 27, 2013
APPL NO 13/815380
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/04 (20130101) Original (OR) Class
F42B 12/02 (20130101)
F42B 12/20 (20130101)
F42B 12/36 (20130101)
F42B 22/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931416 Schneider et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Shawn P. Schneider (King George, Virginia);  Steven C. Tebrich (Fredericksburg, Virginia);  Marin A. Kobin (Fredericksburg, Virginia);  Seth L. Williamson (King George, Virginia);  Bradford Scott Smith (Fredericksburg, Virginia);  Stephen Dix (Fredericksburg, Virginia)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (, None)
INVENTOR(S) Shawn P. Schneider (King George, Virginia);  Steven C. Tebrich (Fredericksburg, Virginia);  Marin A. Kobin (Fredericksburg, Virginia);  Seth L. Williamson (King George, Virginia);  Bradford Scott Smith (Fredericksburg, Virginia);  Stephen Dix (Fredericksburg, Virginia)
ABSTRACT An inert axisymmetric projectile is provided for launching from a shipboard gun and dispersing submunitions at a target. The projectile includes a base plug, a sabot housing, a submunitions package, and a retainer ring. The sabot housing includes a plurality of sabot petals angularly arranged and attached to the plug. The housing includes a payload portion and a nose portion, with a passage corridor between these portions. The submunitions package is contained within the payload portion and constrained radially by the housing. The retainer ring constrains the petals for joining together. Upon launch aerodynamic pressure fractures the ring and causes the petals to unfurl, thereby releasing the submunitions package for dispersal.
FILED Thursday, March 07, 2013
APPL NO 13/788436
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/60 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931490 Ingber et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Donald E. Ingber (Boston, Massachusetts);  Robert J. Mannix (Boston, Massachusetts);  Sanjay Kumar (Moraga, California)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Donald E. Ingber (Boston, Massachusetts);  Robert J. Mannix (Boston, Massachusetts);  Sanjay Kumar (Moraga, California)
ABSTRACT The present invention relates to signaling mechanisms that transduce magnetic inputs into physiological cellular outputs. More particularly, the present invention relates to systems and methods for non-invasively controlling cellular signaling functions and behaviors by harnessing receptor-mediated and intracellular molecular-mediated signal transduction using nanomagnetic cellular switches.
FILED Wednesday, April 09, 2008
APPL NO 12/595306
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0052 (20130101) Original (OR) Class
A61K 47/48507 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/904 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931601 Burt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Jonathan P. Burt (Sturbridge, Massachusetts);  James Jones (Palm City, Florida);  Steven J. Bauer (East Haddam, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Jonathan P. Burt (Sturbridge, Massachusetts);  James Jones (Palm City, Florida);  Steven J. Bauer (East Haddam, Connecticut)
ABSTRACT An assembly for dampening vibration movement between a cylinder and a concentric duct, where the cylinder is positioned radially inside the duct, includes a damper attached to the duct. The damper includes a housing attached to the duct, a contact member positioned at least partially inside the housing and having a contact surface adjacent an outer surface of the cylinder, and a cap threadedly engaged with the housing for applying a load on the contact member in a direction toward the cylinder.
FILED Friday, November 05, 2010
APPL NO 12/940744
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 9/34 (20130101)
F16F 15/021 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931606 Hawkins et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) Gary F. Hawkins (Torrance, California);  Ching-Yao Tang (Alhambra, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Gary F. Hawkins (Torrance, California);  Ching-Yao Tang (Alhambra, California)
ABSTRACT Force diversion apparatus, methods and devices including the same result in rotational motion being imparted to an impacting object.
FILED Saturday, November 29, 2008
APPL NO 12/325171
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 13/0518 (20130101)

Hats; Head Coverings
A42B 3/064 (20130101)

Springs; Shock-absorbers; Means for Damping Vibration
F16F 1/50 (20130101) Original (OR) Class
F16F 1/428 (20130101)
F16F 3/0876 (20130101)

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 5/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931738 White et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Phillip Craige White (Tucson, Arizona);  Robert L. Sisk, III (Sahuarita, Arizona);  Brian S. Scott (Vail, Arizona);  Larry A. Coleman (Tucson, Arizona);  Gary H. Johnson (Tucson, Arizona)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Phillip Craige White (Tucson, Arizona);  Robert L. Sisk, III (Sahuarita, Arizona);  Brian S. Scott (Vail, Arizona);  Larry A. Coleman (Tucson, Arizona);  Gary H. Johnson (Tucson, Arizona)
ABSTRACT A protective cover (10) for an instrument dome (12) extending from a body (20) of a vehicle, such as a missile. The cover (10) includes multiple segments (14 and 16) having trailing ends (18) connectable to the body (20) at joints (22) that allow for rotational movement. The cover (10) further includes a releasable holder (26) that includes a retention device (28) that holds leading ends (24) of the segments (14 and 16) together, and a release mechanism (30) for causing the retention device (28) to release the leading ends (24). The joints (22) hold the trailing ends (18) of the segments (14 and 16) to the body (20) through a predetermined range of motion beyond which the segments (14 and 16) will be released to separate from the body (20) when the segments (14 and 16) rotate beyond the predetermined range.
FILED Tuesday, February 21, 2012
APPL NO 13/401768
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/121
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931961 Owen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Joseph M. Owen (Derry, New Hampshire);  David P. Kelly (Nashua, New Hampshire)
ABSTRACT A fiber-optic connector for connecting an optical fiber to other optical assemblies is disclosed. The fiber-optic connector includes a top plate having a window of similar refractive index and transmission index as the material of an optic fiber to be contained within the fiber-optic connector. The fiber-optic connector also includes a ferrule connected to the top plate via multiple spring-loaded screws. The ferrule includes an interface and an insert. The insert is capable of firmly gripping an optical fiber. In order to reduce Fresnel reflection losses of the fiber-optic connector, the window is pre-coated with an anti-reflective surface on the side opposite an optic fiber to be contained within the fiber-optic connector.
FILED Thursday, September 26, 2013
APPL NO 14/038034
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/3818 (20130101)
G02B 6/3849 (20130101)
G02B 6/3855 (20130101) Original (OR) Class
G02B 6/3861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932092 Sadowski
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Thaddeus J. Sadowski (Hampton, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Thaddeus J. Sadowski (Hampton, Virginia)
ABSTRACT The invention is directed to a waterjet propulsor. The propulsor includes a structure covering an impeller shaft. The implementation of the elongated structure results in reduced drag, increased thrust and increased craft speed. The elongated structure may be a sleeve that is mounted in a free-floating arrangement over the impeller shaft that self-aligns, the sleeve having an airfoil cross section for optimizing the flow of water over the shaft. The elongated structure may also be a fixed housing arrangement that includes an airfoil cross section for optimizing the flow of water over the shaft.
FILED Tuesday, June 18, 2013
APPL NO 13/920214
ART UNIT 3617 — Optics
CURRENT CPC
Marine Propulsion or Steering
B63H 11/08 (20130101) Original (OR) Class
B63H 2011/081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932199 Berka et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Advanced Brain Monitoring, Inc. (Carlsbad, California)
ASSIGNEE(S) Advanced Brain Monitoring, Inc. (Carlsbad, California)
INVENTOR(S) Christine Berka (Carlsbad, California);  Djordje Popovic (Carlsbad, California);  Dan Levendowski (Carlsbad, California);  Gene Davis (Carlsbad, California);  Catherine McConnell (Carlsbad, California);  Matthew A. Yanagi (Carlsbad, California)
ABSTRACT Sleep mask for reducing sleep inertia. In an embodiment, the sleep mask comprises a foam layer having a shape that covers both of a human subject's eyes so as to attenuate ambient light. Visual stimulation element(s), configured to emit light, are positioned between the foam layer and the subject's eyes. In addition, a plurality of sensors positioned on the forehead of the subject collect electroencephalogram (EEG), electrooculogram (EOG), and electromyogram (EMG) signals. A soft exterior cover houses the foam layer, the visual stimulation element(s), and the sensors. The sleep mask further comprises processor(s) that determine and record each sleep stage of the subject, determine when to wake the subject, and, when it is determined to wake the subject, control the visual stimulation element(s) to wake the subject using emitted light.
FILED Monday, June 23, 2014
APPL NO 14/312345
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0476 (20130101)
A61B 5/0488 (20130101)
A61B 5/0496 (20130101)
A61B 5/4812 (20130101)
A61B 5/4836 (20130101)
A61B 5/6803 (20130101)
A61B 5/7475 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/02 (20130101) Original (OR) Class
A61M 2021/0022 (20130101)
A61M 2021/0027 (20130101)
A61M 2021/0044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932294 Fleischmann
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) David Fleischmann (Tempe, Arizona)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David Fleischmann (Tempe, Arizona)
ABSTRACT A device and method for providing antimicrobial activity around a surgical implant. Antimicrobial activity is provided by the inclusion of a highly conductive material to a surgical implant and providing a low electrical charge to the implant. Electrical charge is provided by a static generator or battery attached to the implant or attached via electrical leads.
FILED Wednesday, August 29, 2012
APPL NO 13/597576
ART UNIT 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/68 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/14 (20130101)
A61L 31/16 (20130101)
A61L 31/088 (20130101) Original (OR) Class
A61L 2300/102 (20130101)
A61L 2300/104 (20130101)
A61L 2300/404 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932468 Favreau et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Nicole Favreau (Waltham, Massachusetts);  Ferdinando F. Bruno (Andover, Massachusetts)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Nicole Favreau (Waltham, Massachusetts);  Ferdinando F. Bruno (Andover, Massachusetts)
ABSTRACT Disclosed is a process for the separation of one or more fractions from a resulting reaction mixture of an enzymatically catalyzed polymerization of flavonoid using HPLC with a varying concentration of organic solvent in the mobile phase. The isolated fractions can be used in numerous applications including as an antioxidant.
FILED Tuesday, January 12, 2010
APPL NO 12/635729
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 15/166 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932494 Liao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Yi Liao (Orlando, Florida);  Zheng Shi (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Yi Liao (Orlando, Florida);  Zheng Shi (Orlando, Florida)
ABSTRACT A method for forming electrically conductive polyaniline (PANI)-based composites includes mixing a base form of PANI, a photo acid generator (PAG), and when the PAG does not hydrogen bond to the base form of PANI an additive which can form hydrogen bonds with the base form of PANI or PAG, together with at least one solvent to form a mixture. The solvent is removed from the mixture. After the removing, the mixture is photo-irradiated with a wavelength within an absorption band of the PAG for converting the base form of PANI to a salt form of PANI to form a polymer composite that includes the salt form of PANI. The polymer composite has a 25° C. electrical conductivity that is at least 3 orders of magnitude higher than a 25° C. electrical conductivity of the base form of PANI, such as a 25° C. electrical conductivity of ≧0.01 S/cm.
FILED Tuesday, May 03, 2011
APPL NO 13/099971
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/128 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932828 Rosendahl et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Mary S. Rosendahl (Broomfield, Colorado);  George N. Cox (Louisville, Colorado);  Daniel H. Doherty (Boulder, Colorado)
ASSIGNEE(S) Bolder Biotechnology, Inc. (Boulder, Colorado)
INVENTOR(S) Mary S. Rosendahl (Broomfield, Colorado);  George N. Cox (Louisville, Colorado);  Daniel H. Doherty (Boulder, Colorado)
ABSTRACT The present invention relates to novel methods for making and refolding insoluble or aggregated proteins having free cysteines in which a host cell expressing the protein is exposed to a cysteine blocking agent. The soluble, refolded proteins produced by the novel methods can then be modified to increase their effectiveness. Such modifications include attaching a PEG moiety to form PEGylated proteins.
FILED Wednesday, September 29, 2010
APPL NO 12/893764
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48215 (20130101)

Peptides
C07K 1/1133 (20130101)
C07K 14/52 (20130101) Original (OR) Class
C07K 14/56 (20130101)
C07K 14/61 (20130101)
C07K 14/78 (20130101)
C07K 14/505 (20130101)
C07K 14/515 (20130101)
C07K 14/535 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932869 Walt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) David R. Walt (Boston, Massachusetts);  Sandra Bencic-Nagale (Lowell, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Boston, Massachusetts)
INVENTOR(S) David R. Walt (Boston, Massachusetts);  Sandra Bencic-Nagale (Lowell, Massachusetts)
ABSTRACT Certain embodiments of the present invention relate to the preparation of microbeads that exhibit a “turn on” fluorescence response within seconds of exposure to an analyte vapor (e.g., a chemical warfare agent or a reactive stimulant). This sensing approach is modeled after the mechanism for inhibition of acetylcholinesterase enzyme activity, and utilizes a specific and irreversible reaction between phosphonyl halides and a fluorescent indicator. The present invention also relates to a sensor and a method for sensing an analyte through detection of changes in the fluorescing properties of the inventive microbeads.
FILED Thursday, February 22, 2007
APPL NO 12/279899
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Heterocyclic Compounds
C07D 219/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/643 (20130101)
G01N 33/0057 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932894 Christophersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Marc Christophersen (Berwyn Heights, Maryland);  Bernard F. Phlips (Great Falls, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secratary of the Navy (Washington, District of Columbia)
INVENTOR(S) Marc Christophersen (Berwyn Heights, Maryland);  Bernard F. Phlips (Great Falls, Virginia)
ABSTRACT Gray tone lithography is used to form curved silicon topographies for semiconductor based solid-state imaging devices. The imagers are curved to a specific curvature and shaped directly for the specific application; such as curved focal planes. The curvature of the backside is independent from the front surface, which allows thinning of the detector using standard semiconductor processing.
FILED Monday, October 19, 2009
APPL NO 12/581469
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/115 (20130101)
H01L 31/1804 (20130101) Original (OR) Class
H01L 31/022408 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/547 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932974 Garcia-Martinez
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Javier Garcia-Martinez (Alicante, Spain)
ABSTRACT One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for organic compounds and degradation catalysts for polymers.
FILED Wednesday, July 17, 2013
APPL NO 13/944694
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/18 (20130101)
B01J 20/186 (20130101)
B01J 29/005 (20130101)
B01J 29/18 (20130101)
B01J 29/40 (20130101) Original (OR) Class
B01J 29/041 (20130101)
B01J 29/80 (20130101)
B01J 29/084 (20130101)
B01J 29/106 (20130101)
B01J 29/0308 (20130101)
B01J 2229/62 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 39/02 (20130101)
C01B 39/04 (20130101)
C01B 39/023 (20130101)
C01B 39/026 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 1/086 (20130101)
C10G 11/02 (20130101)
C10G 11/05 (20130101)
C10G 11/18 (20130101)
C10G 45/04 (20130101)
C10G 47/02 (20130101)
C10G 2300/1033 (20130101)
C10G 2300/1074 (20130101)
C10G 2300/1096 (20130101)
C10G 2400/02 (20130101)
C10G 2400/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932977 Dismukes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Multidisciplinary University Research Initiative (MURI)
APPLICANT(S) G. Charles Dismukes (Princeton, New Jersey);  Martha Greenblatt (Highland Park, New Jersey)
ASSIGNEE(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) G. Charles Dismukes (Princeton, New Jersey);  Martha Greenblatt (Highland Park, New Jersey)
ABSTRACT A catalyst for the electrolysis of water molecules and hydrocarbons, the catalyst including catalytic groups comprising A1-xB2-yB′yO4 spinels having a cubical M4O4 core, wherein A is Li or Na, B and B′ are independently any transition metal or main group metal, M is B, B′, or both, x is a number from 0 to 1, and y is a number from 0 to 2. In photo-electrolytic applications, a plurality of catalytic groups are supported on a conductive support substrate capable of incorporating water molecules. At least some of the catalytic groups, supported by the support substrate, are able to catalytically interact with water molecules incorporated into the support substrate. The catalyst can also be used as part of a photo-electrochemical cell for the generation of electrical energy.
FILED Friday, June 24, 2011
APPL NO 13/643439
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 35/004 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/003 (20130101) Original (OR) Class
C25B 3/02 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/366 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 502/524 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933082 Clapp et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) D Wade Clapp (Indianapolis, Indiana);  David Ingram (Indianapolis, Indiana);  Feng-Chun Yang (Carmel, Indiana)
ASSIGNEE(S) Indiana University Research and Technology Corp. (Indianapolis, Indiana)
INVENTOR(S) D Wade Clapp (Indianapolis, Indiana);  David Ingram (Indianapolis, Indiana);  Feng-Chun Yang (Carmel, Indiana)
ABSTRACT Germline mutations in the NF1 tumor suppressor gene cause Von Recklinghausen's neurofibromatosis type 1 (NF1), a common genetic disorder of the nervous system characterized by plexiform neurofibroma development. Using adoptive transfer of hematopoietic cells, we establish that NF1 heterozygosity of bone marrow derived cells in the tumor microenvironment is sufficient to allow neurofibroma progression in the context of Schwann cell nullizygosity. Further, genetic or pharmacologic attenuation of the c-kit signaling pathway in hematopoietic cells greatly diminishes neurofibroma initiation and progression. These studies identify haploinsufficient hematopoietic cells and the c-kit receptor as therapeutic targets for preventing plexiform neurofibromas and implicate mast cells as critical mediators of tumor initiation. Administering therapeutically effective doses of a tyrosine kinase inhibitor such as the compound imatinib mesylate to a patient in need thereof to treat tumors in a human patient afflicted with plexiform neurofibroma.
FILED Friday, September 20, 2013
APPL NO 14/032994
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/255.50
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933301 Hurst et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Susan R. Hurst (Seattle, Washington);  Dayna L. Loeffler (Seattle, Washington);  Michael N. Steine (Kent, Washington);  Anna Amen (Redmond, Washington);  Dionne Vafeados (Snohomish, Washington)
ASSIGNEE(S) Arcadia Biosciences, Inc. (Davis, California)
INVENTOR(S) Susan R. Hurst (Seattle, Washington);  Dayna L. Loeffler (Seattle, Washington);  Michael N. Steine (Kent, Washington);  Anna Amen (Redmond, Washington);  Dionne Vafeados (Snohomish, Washington)
ABSTRACT The present invention provides a series of independent human-induced, non-transgenic mutations found in at least one tomato β-galactosidase 4 gene, tomato plants having these mutations in at least one of their tomato β-galactosidase 4 genes, and a method of creating and identifying similar and/or additional mutations in the tomato β-galactosidase 4 gene by screening pooled and/or individual tomato plants. Tomato plants identified and produced in accordance with the present invention have fruit that are firmer when ripe with reduced post-harvest softening compared to fruit from wild type tomato plants as a result of non-transgenic mutations in at least one of their tomato β-galactosidase 4 genes.
FILED Wednesday, December 22, 2010
APPL NO 12/976995
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 1/06 (20130101)
A01H 5/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933383 Celmins
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Ilmars Celmins (Whiteford, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Ilmars Celmins (Whiteford, Maryland)
ABSTRACT A system and method of trajectory correction includes a voice coil coupled to the projectile and providing a linear force; a linkage assembly coupled to the voice coil and comprising: a linkage shaft; a slot coupled to the linkage shaft; and a pin loosely coupled to the slot to form a first pivot point, wherein the linkage assembly converts the linear force to a torque force through the first pivot point; and a canard assembly coupled to the linkage assembly and including a canard shaft coupled to the linkage shaft to form a second pivot point; and at least one canard coupled to the canard shaft, wherein the torque force is transmitted to canard shaft by the linkage shaft, and wherein the canard shaft transmits the torque force to the canard to correct the trajectory of the projectile.
FILED Wednesday, September 01, 2010
APPL NO 12/924035
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/3.240
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933425 Bevis
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Christopher F. Bevis (Los Gatos, California)
ASSIGNEE(S) KLA-Tencor Corporation (Milpitas, California)
INVENTOR(S) Christopher F. Bevis (Los Gatos, California)
ABSTRACT One embodiment relates to an apparatus for aberration correction in an electron beam lithography system. An inner electrode surrounds a pattern generating device, and there is at least one outer electrode around the inner electrode. Each of the inner and outer electrodes has a planar surface in a plane of the pattern generating device. Circuitry is configured to apply an inner voltage level to the inner electrode and at least one outer voltage level to the at least one outer electrode. The voltage levels may be set to correct a curvature of field in the electron beam lithography system. Another embodiment relates to an apparatus for aberration correction used in an electron based system, such as an electron beam inspection, or review, or metrology system. Other embodiments, aspects and features are also disclosed.
FILED Wednesday, November 02, 2011
APPL NO 13/287682
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/3174 (20130101) Original (OR) Class
H01J 2237/1534 (20130101)
H01J 2237/31788 (20130101)
H01J 2237/31789 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933486 Wu
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Yifeng Wu (Goleta, California)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Yifeng Wu (Goleta, California)
ABSTRACT A transistor with source and drain electrodes formed in contact with an active region and a gate between the source and drain electrodes and in contact with the active region. A first spacer layer is on at least part of the active region surface between the gate and drain electrodes and between the gate and source electrodes. The gate comprises a generally t-shaped top portion that extends toward the source and drain electrodes. A field plate is on the spacer layer and under the overhang of at least one section of the gate top portion. The field plate is at least partially covered by a second spacer layer that is on at least part of the first active layer surface and between the gate and drain and between the gate and source. At least one conductive path electrically connects the field plate to the source electrode or the gate.
FILED Monday, September 26, 2011
APPL NO 13/245579
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/402 (20130101)
H01L 29/778 (20130101) Original (OR) Class
H01L 29/8128 (20130101)
H01L 29/42316 (20130101)
H01L 29/66462 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933695 Kornev et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Victor K. Kornev (Moscow, Russian Federation);  Igor I. Soloviev (Moscow, Russian Federation);  Nikolai V. Klenov (Troitsk, Russian Federation);  Oleg A. Mukhanov (Putnam Valley, New York)
ASSIGNEE(S) Hypres, Inc. (Elmsford, New York)
INVENTOR(S) Victor K. Kornev (Moscow, Russian Federation);  Igor I. Soloviev (Moscow, Russian Federation);  Nikolai V. Klenov (Troitsk, Russian Federation);  Oleg A. Mukhanov (Putnam Valley, New York)
ABSTRACT A superconducting quantum interference devices (SQUID) comprises a superconducting inductive loop with at least two Josephson junction, whereby a magnetic flux coupled into the inductive loop produces a modulated response up through radio frequencies. Series and parallel arrays of SQUIDs can increase the dynamic range, output, and linearity, while maintaining bandwidth. Several approaches to achieving a linear triangle-wave transfer function are presented, including harmonic superposition of SQUID cells, differential serial arrays with magnetic frustration, and a novel bi-SQUID cell comprised of a nonlinear Josephson inductance shunting the linear coupling inductance. Total harmonic distortion of less than −120 dB can be achieved in optimum cases.
FILED Tuesday, May 15, 2012
APPL NO 13/471674
ART UNIT 2867 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/248
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933759 Kubena et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Randy L. Kubena (Oak Park, California);  Deborah J. Kirby (Calabasas, California)
ABSTRACT A shear-mode quartz resonator designed to mechanically oscillate at a predetermined frequency and electronic circuits for inhibiting oscillation of the shear-mode quartz resonator in response to externally applied mechanical forces which otherwise induce mechanical vibration of the shear-mode quartz resonator at frequencies significantly less than the predetermined frequency. The shear-mode quartz resonator includes a cantilevered quartz beam having relatively large metallic electrodes attached on opposite sides thereof, the relatively large metallic electrodes, in use, being coupled to an external oscillator circuit. The beam also has relatively smaller sense and rebalance electrodes attached on the same opposite sides of said quartz beam as said relatively large metallic electrodes. The relatively smaller sense and rebalance electrodes being coupled, in use, with said electronic circuits for inhibiting oscillation of the shear-mode quartz resonator in response to externally applied mechanical forces.
FILED Friday, June 28, 2013
APPL NO 13/931321
ART UNIT 2843 — Printing/Measuring and Testing
CURRENT CPC
Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 1/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933769 Houck et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) William D. Houck (Blacksburg, Virginia);  David W. Sherrer (Radford, Virginia)
ASSIGNEE(S) Nuvotronics, LLC (Radford, Virginia)
INVENTOR(S) William D. Houck (Blacksburg, Virginia);  David W. Sherrer (Radford, Virginia)
ABSTRACT Provided are three-dimensional microstructures and their methods of formation. The microstructures are formed by a sequential build process and include microstructural elements which are affixed to one another. The microstructures find use, for example, in coaxial transmission lines for electromagnetic energy.
FILED Monday, August 29, 2011
APPL NO 13/219736
ART UNIT 2843 — Printing/Measuring and Testing
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0059 (20130101)
B81B 2203/0109 (20130101)
B81B 2203/0307 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/06 (20130101)
H01P 11/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933832 Kelly et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Michael Kelly (North Reading, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S) The Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Michael Kelly (North Reading, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ABSTRACT Autonomously operating analog to digital converters are formed into a two dimensional array. The array may incorporate digital signal processing functionality. Such an array is particularly well-suited for operation as a readout integrated circuit and, in combination with a sensor array, forms a digital focal plane array.
FILED Thursday, April 12, 2012
APPL NO 13/445433
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 1/60 (20130101)
H03M 1/145 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934096 Herzinger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Craig M. Herzinger (Lincoln, Nebraska);  Mathias M. Schubert (Lincoln, Nebraska);  Tino Hofmann (Lincoln, Nebraska);  Martin M. Liphardt (Lincoln, Nebraska);  John A. Woollam (Lincoln, Nebraska)
ASSIGNEE(S) University of Nebraska Board of Regents (Lincoln, Nebraska);  J.A. Woollam Co., Inc. (Lincoln, Nebraska)
INVENTOR(S) Craig M. Herzinger (Lincoln, Nebraska);  Mathias M. Schubert (Lincoln, Nebraska);  Tino Hofmann (Lincoln, Nebraska);  Martin M. Liphardt (Lincoln, Nebraska);  John A. Woollam (Lincoln, Nebraska)
ABSTRACT The present invention relates to ellipsometer and polarimeter systems, and more particularly is an ellipsometer or polarimeter or the like system which operates in a frequency range between 300 GHz or lower and extending to higher than at least 1 Tera-hertz (THz), and preferably through the Infra-red (IR) range up to, and higher than 100 THz, including: a source such as a backward wave oscillator; a Smith-Purcell cell; a free electron laser, or an FTIR source and a solid state device; and a detector such as a Golay cell; a bolometer or a solid state detector;
and preferably including at least one odd-bounce polarization state image rotating system, and optionally including a polarizer, at least one compensator and/or modulator, in addition to an analyzer.
FILED Friday, May 11, 2012
APPL NO 13/506707
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 4/04 (20130101) Original (OR) Class
G01J 5/20 (20130101)
G01J 5/42 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/211 (20130101)
G01N 21/3581 (20130101)
G01N 2021/3595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934741 Chen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Reconnaissance Office (NRO)
APPLICANT(S) Baoquan Chen (Bothell, Washington);  Hui Chen (Kirkland, Washington);  Raluca Dinu (Redmond, Washington);  Diyun Huang (Watertown, Massachusetts);  Bing Li (Bothell, Washington);  Eric Miller (Seattle, Washington);  Danliang Jin (Bothell, Washington);  Christopher A. Wiklof (Everett, Washington);  Guomin Yu (Bothell, Washington)
ASSIGNEE(S) Brphotonics Produtos Optoelectronicos LTDA (Sao Paulo, Brazil)
INVENTOR(S) Baoquan Chen (Bothell, Washington);  Hui Chen (Kirkland, Washington);  Raluca Dinu (Redmond, Washington);  Diyun Huang (Watertown, Massachusetts);  Bing Li (Bothell, Washington);  Eric Miller (Seattle, Washington);  Danliang Jin (Bothell, Washington);  Christopher A. Wiklof (Everett, Washington);  Guomin Yu (Bothell, Washington)
ABSTRACT An integrated circuit is configured for optical communication via an optical polymer stack located on top of the integrated circuit. The optical polymer stack may include one or more electro-optic polymer devices including an electro-optic polymer. The electro-optic polymer may include a host polymer and a second order nonlinear chromomophore, the host polymer and the chromophore both including aryl groups configured to interact with one another to provide enhanced thermal and/or temporal stability.
FILED Wednesday, December 08, 2010
APPL NO 12/963479
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/1221 (20130101) Original (OR) Class
G02B 6/12004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935035 Bogdanowicz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Zbigniew Bogdanowicz (Morganville, New Jersey);  George Herc (Randolph, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Zbigniew Bogdanowicz (Morganville, New Jersey);  George Herc (Randolph, New Jersey)
ABSTRACT An optimization framework for air and ground based persistent surveillance using unmanned vehicles. The objective of the optimization framework is to maximize the coverage of a target area for given UVs, skeleton, and maintenance sites. The optimization framework is based on the generation of mini-cycles, and assigning them in a fractional manner to the given UVs. Subsequently, the optimization framework based on UV-Cross and UV-k-Swap transformations, followed by the cycle of fusion, integerization, and schedule synchronization.
FILED Wednesday, December 21, 2011
APPL NO 13/332493
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Traffic Control Systems
G08G 1/00 (20130101) Original (OR) Class
G08G 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935098 Di Carlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
National Science Foundation (NSF)
APPLICANT(S) Dino Di Carlo (Los Angeles, California);  Daniel R. Gossett (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dino Di Carlo (Los Angeles, California);  Daniel R. Gossett (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ABSTRACT A system is disclosed that enables the automated measurement of cellular mechanical parameters at high throughputs. The microfluidic device uses intersecting flows to create an extensional flow region where the cells undergo controlled stretching. Cells are focused into streamlines prior to entering the extensional flow region. In the extensional region, each cell's deformation is measured with an imaging device. Automated image analysis extracts a range of independent biomechanical parameters from the images. These may include cell size, deformability, and circularity. The single cell data that is obtained may then be used to in a variety of ways. Scatter density plots of deformability and circularity may be developed and displayed for the user. Mechanical parameters such as deformability and circularity may be gated or thresholded to identify certain cells of interest or sub-populations of interest. Similarly, the mechanical data obtained using the device may be used as cell signatures.
FILED Friday, September 16, 2011
APPL NO 13/823109
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1459 (20130101)
G01N 15/1484 (20130101)
G01N 33/574 (20130101)
G01N 2015/1495 (20130101)

Electric Digital Data Processing
G06F 19/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935189 Tyson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Interior (DOI)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Mabry W. Tyson (Los Altos, California);  Douglas E. Appelt (Palo Alto, California);  Min Yin (San Jose, California);  William Jarrold (Davis, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Mabry W. Tyson (Los Altos, California);  Douglas E. Appelt (Palo Alto, California);  Min Yin (San Jose, California);  William Jarrold (Davis, California)
ABSTRACT A non-transitory computer readable storage medium includes instructions to collect explicit feedback from a user regarding user content preferences. Multiple data sources are monitored. Topics associated with the multiple data sources are classified. The importance of the topics to the user is characterized. Content is delivered to the user when a selected topic exceeds an importance threshold for the user. Implicit feedback from the user that characterizes refined user content preferences is tracked. The instructions to characterize the importance of topics evaluates the explicit feedback and the implicit feedback.
FILED Friday, May 27, 2011
APPL NO 13/118226
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/30997 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 30/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935319 Calo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Seraphin Bernard Calo (Cortlandt Manor, New York);  Raheleh B. Dilmaghani (Elmsford, New York);  Douglas M. Freimuth (New York, New York);  Raghu K. Ganti (Elmsford, New York);  Keith William Grueneberg (Stewart Manor, New York);  Fan Ye (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Seraphin Bernard Calo (Cortlandt Manor, New York);  Raheleh B. Dilmaghani (Elmsford, New York);  Douglas M. Freimuth (New York, New York);  Raghu K. Ganti (Elmsford, New York);  Keith William Grueneberg (Stewart Manor, New York);  Fan Ye (Ossining, New York)
ABSTRACT A common infrastructure collects diverse data and information from large numbers of mobile devices and traditional sensors at Internet scale to support multiple different applications simultaneously. The infrastructure includes a backend phenomenon layer that provides high level abstractions to applications such that they can express their data and information needs in a declarative fashion and coordinate the data collection and processing activities for all applications. An edge layer that manages devices, receives collection requirements from the backend layer, configures and instructs devices for data collection, and conducts aggregation and primitive processing of the data. This layer contains network edge nodes, such as base stations in a cellular network. Each node manages a set of local data generating networked devices. The device agent data layer using common agents on the data generating networked devices receives data collection instructions from the edge layer, performs data collection.
FILED Tuesday, May 15, 2012
APPL NO 13/472098
ART UNIT 2442 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 29/08072 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935368 Calo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Seraphin Bernard Calo (Cortlandt Manor, New York);  Raheleh B Dilmaghani (Elmsford, New York);  Douglas M Freimuth (New York, New York);  Raghu Kiran Ganti (Elmsford, New York);  Keith William Grueneberg (Stewart Manor, New York);  Fan Ye (Ossining, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Seraphin Bernard Calo (Cortlandt Manor, New York);  Raheleh B Dilmaghani (Elmsford, New York);  Douglas M Freimuth (New York, New York);  Raghu Kiran Ganti (Elmsford, New York);  Keith William Grueneberg (Stewart Manor, New York);  Fan Ye (Ossining, New York)
ABSTRACT A common infrastructure collects diverse data and information from large numbers of mobile devices and traditional sensors at Internet scale to support multiple different applications simultaneously. The infrastructure includes a backend phenomenon layer that provides high level abstractions to applications such that they can express their data and information needs in a declarative fashion and coordinate the data collection and processing activities for all applications. An edge layer that manages devices, receives collection requirements from the backend layer, configures and instructs devices for data collection, and conducts aggregation and primitive processing of the data. This layer contains network edge nodes, such as base stations in a cellular network. Each node manages a set of local data generating networked devices. The device agent data layer using common agents on the data generating networked devices receives data collection instructions from the edge layer, performs data collection.
FILED Monday, April 16, 2012
APPL NO 13/447936
ART UNIT 2442 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 29/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935773 Stavrou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Materiel Command (AMC)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Angelos Stavrou (Springfield, Virginia);  Sushil Jajodia (Oakton, Virginia);  Anup Ghosh (Centreville, Virginia);  Rhandi Martin (St. James, Barbados);  Charalampos Andrianakis (Crete, Greece)
ASSIGNEE(S) George Mason Research Foundation, Inc. (Fairfax, Virginia)
INVENTOR(S) Angelos Stavrou (Springfield, Virginia);  Sushil Jajodia (Oakton, Virginia);  Anup Ghosh (Centreville, Virginia);  Rhandi Martin (St. James, Barbados);  Charalampos Andrianakis (Crete, Greece)
ABSTRACT A transparent proxy for malware detection includes a monitor module, a protocol determination module, a challenge generation module, a response determination module, and a data control module. The monitor module examines data originating from an application towards a remote server. The protocol determination module identifies the protocol type used for the data. The challenge generation module produces a challenge for the application based upon the protocol type, sends the challenge to the application, and maintains a state related to the data and the challenge. The response determination module makes a determination if an automatic non-interactive application response is received in response to the challenge from the application. The data control module allows the first data to continue to the remote server when the determination is valid. The data control module reports malware detection and blocks the data to continue to the remote server when the determination is invalid.
FILED Friday, April 09, 2010
APPL NO 12/757675
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/566 (20130101)
G06F 2221/2103 (20130101)
G06F 2221/2119 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/08 (20130101)
H04L 63/145 (20130101)
H04L 63/0884 (20130101) Original (OR) Class
H04L 67/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935775 Fryman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Joshua Fryman (Corvallis, Oregon);  Nicholas Carter (Hillsboro, Oregon);  Robert Knauerhase (Portland, Oregon);  Sebastian Schoenberg (Hillsboro, Oregon);  Aditya Agrawal (Urbana, Illinois)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Joshua Fryman (Corvallis, Oregon);  Nicholas Carter (Hillsboro, Oregon);  Robert Knauerhase (Portland, Oregon);  Sebastian Schoenberg (Hillsboro, Oregon);  Aditya Agrawal (Urbana, Illinois)
ABSTRACT A system implements dishonest policies for managing unauthorized access requests. The system includes memory management hardware to store a set of dishonest policy bits, each dishonest policy bit that is configured to a predetermined value indicating disallowed access for one of a set of memory ranges. When a processor receives an access request for a location in a memory range to which access is not allowed as indicated by a set dishonest policy bit, the processor returns a false indication according to a dishonest policy that the requested access has been performed.
FILED Friday, September 28, 2012
APPL NO 13/630592
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 12/00 (20130101)
G06F 12/14 (20130101) Original (OR) Class
G06F 13/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 08931431 Forrest et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Solid-State Lighting Program (SSL)
APPLICANT(S) Stephen R. Forrest (Ann Harbor, Michigan);  Gregory McGraw (Ann Harbor, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Harbor, Michigan);  Gregory McGraw (Ann Harbor, Michigan)
ABSTRACT A first device is provided. The device includes a print head. The print head further includes a first nozzle hermetically sealed to a first source of gas. The first nozzle has an aperture having a smallest dimension of 0.5 to 500 microns in a direction perpendicular to a flow direction of the first nozzle. At a distance from the aperture into the first nozzle that is 5 times the smallest dimension of the aperture of the first nozzle, the smallest dimension perpendicular to the flow direction is at least twice the smallest dimension of the aperture of the first nozzle.
FILED Tuesday, March 23, 2010
APPL NO 12/729448
ART UNIT 1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors
B41J 2/005 (20130101) Original (OR) Class

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/04 (20130101)
C23C 14/12 (20130101)
C23C 14/228 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931553 Cannan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Carbo Ceramics Inc. (Houston, Texas);  Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S) CARBO Ceramics Inc. (Houston, Texas);  Sandia Coporation (Albuquerque, New Mexico)
INVENTOR(S) Chad Cannan (Cypress, Texas);  Lewis Bartel (Albuquerque, New Mexico);  Terrence Palisch (Richardson, Texas);  David Aldridge (Albuquerque, New Mexico)
ABSTRACT Electrically conductive proppants and methods for detecting, locating, and characterizing same are provided. The electrically conductive proppant can include a substantially uniform coating of an electrically conductive material having a thickness of at least 500 nm. The method can include injecting a hydraulic fluid into a wellbore extending into a subterranean formation at a rate and pressure sufficient to open a fracture therein, injecting into the fracture a fluid containing the electrically conductive proppant, electrically energizing the earth at or near the fracture, and measuring three dimensional (x, y, and z) components of electric and magnetic field responses at a surface of the earth or in an adjacent wellbore.
FILED Friday, January 03, 2014
APPL NO 14/147372
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/25 (20130101) Original (OR) Class
E21B 47/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931950 King et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) William P. King (Champaign, Illinois);  Jungchul Lee (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) William P. King (Champaign, Illinois);  Jungchul Lee (Champaign, Illinois)
ABSTRACT In one aspect, provided herein is a single crystal silicon microcalorimeter, for example useful for high temperature operation and long-term stability of calorimetric measurements. Microcalorimeters described herein include microcalorimeter embodiments having a suspended structure and comprising single crystal silicon. Also provided herein are methods for making calorimetric measurements, for example, on small quantities of materials or for determining the energy content of combustible material having an unknown composition.
FILED Thursday, August 20, 2009
APPL NO 13/059812
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 17/006 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 25/4813 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/902 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932400 Chen et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Calera Corporation (Los Gatos, California)
ASSIGNEE(S) Calera Corporation (Los Gatos, California)
INVENTOR(S) Irvin Chen (Santa Clara, California);  Miguel Fernandez (San Jose, California);  Joshua Patterson (Watsonville, California);  Martin Devenney (Mountain View, California)
ABSTRACT Provided herein are compositions and methods including hydraulic cement, supplementary cementitious material, and/or self-cementing material. Methods for making the compositions and using the compositions are provided.
FILED Wednesday, January 15, 2014
APPL NO 14/155700
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/62 (20130101)
B01D 2251/404 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0233 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/28 (20130101) Original (OR) Class
C04B 14/28 (20130101)
C04B 14/28 (20130101)
C04B 28/02 (20130101)
C04B 28/02 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/04 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 264/43 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932403 Li et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Qiming Li (Albuquerque, New Mexico);  George T. Wang (Albuquerque, New Mexico)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Qiming Li (Albuquerque, New Mexico);  George T. Wang (Albuquerque, New Mexico)
ABSTRACT A method for forming a surface-textured single-crystal film layer by growing the film atop a layer of microparticles on a substrate and subsequently selectively etching away the microparticles to release the surface-textured single-crystal film layer from the substrate. This method is applicable to a very wide variety of substrates and films. In some embodiments, the film is an epitaxial film that has been grown in crystallographic alignment with respect to a crystalline substrate.
FILED Monday, May 23, 2011
APPL NO 13/113123
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
117/89
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932446 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Shelly X Li (Idaho Falls, Idaho);  Jan-fong Jue (Idaho Falls, Idaho);  Ronald Scott Herbst (Idaho Falls, Idaho);  Steven Douglas Herrmann (Idaho Falls, Idaho)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Shelly X Li (Idaho Falls, Idaho);  Jan-fong Jue (Idaho Falls, Idaho);  Ronald Scott Herbst (Idaho Falls, Idaho);  Steven Douglas Herrmann (Idaho Falls, Idaho)
ABSTRACT An apparatus for the real-time, in-situ monitoring of actinide-ion concentrations. A working electrolyte is positioned within the interior of a container. The working electrolyte is separated from a reference electrolyte by a separator. A working electrode is at least partially in contact with the working electrolyte. A reference electrode is at least partially in contact with the reference electrolyte. A voltmeter is electrically connected to the working electrode and the reference electrode. The working electrolyte comprises an actinide-ion of interest. The separator is ionically conductive to the actinide-ion of interest. The separator comprises an actinide, Zr, and Nb. Preferably, the actinide of the separator is Am or Np, more preferably Pu. In one embodiment, the actinide of the separator is the actinide of interest. In another embodiment, the separator further comprises P and O.
FILED Friday, May 10, 2013
APPL NO 13/891308
ART UNIT 1759 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/26 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932461 Quake et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Stephen R. Quake (Stanford, California);  Joshua S. Marcus (Altadena, California);  Carl L. Hansen (Vancouver, Canada)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Stephen R. Quake (Stanford, California);  Joshua S. Marcus (Altadena, California);  Carl L. Hansen (Vancouver, Canada)
ABSTRACT Sieve valves for use in microfluidic device are provided. The valves are useful for impeding the flow of particles, such as chromatography beads or cells, in a microfluidic channel while allowing liquid solution to pass through the valve. The valves find particular use in making microfluidic chromatography modules.
FILED Tuesday, June 28, 2011
APPL NO 13/171329
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/286 (20130101) Original (OR) Class
B01J 2220/54 (20130101)

Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 99/0001 (20130101)
F16K 99/0026 (20130101)
F16K 99/0034 (20130101)
F16K 99/0059 (20130101)
F16K 2099/008 (20130101)
F16K 2099/0074 (20130101)
F16K 2099/0084 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/603 (20130101)
G01N 30/6004 (20130101)
G01N 30/6095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932513 Fong et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Hao Fong (Rapid City, South Dakota);  Lifeng Zhang (Greensboro, North Carolina);  Yong Zhao (Rapid City, South Dakota);  Zhengtao Zhu (Rapid City, South Dakota)
ASSIGNEE(S) South Dakota Board of Regents (Rapid City, South Dakota)
INVENTOR(S) Hao Fong (Rapid City, South Dakota);  Lifeng Zhang (Greensboro, North Carolina);  Yong Zhao (Rapid City, South Dakota);  Zhengtao Zhu (Rapid City, South Dakota)
ABSTRACT A method of synthesizing mechanically resilient titanium carbide (TiC) nanofibrous felts comprising continuous nanofibers or nano-ribbons with TiC crystallites embedded in carbon matrix, comprising: (a) electrospinning a spin dope for making precursor nanofibers with diameters less than 0.5 J.Lm; (b) overlaying the nanofibers to produce a nanofibrous mat (felt); and then (c) heating the nano-felts first at a low temperature, and then at a high temperature for making electrospun continuous nanofibers or nano-ribbons with TiC crystallites embedded in carbon matrix; and (d) chlorinating the above electrospun nano-felts at an elevated temperature to remove titanium for producing carbide derived carbon (CDC) nano-fibrous felt with high specific surface areas.
FILED Tuesday, May 29, 2012
APPL NO 13/482981
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0023 (20130101)

Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding
D04H 1/728 (20130101) Original (OR) Class
D04H 1/4209 (20130101)
D04H 1/4382 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932520 Goddard et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Gregory R Goddard (Los Alamos, New Mexico);  Gregory Kaduchak (Eugene, Oregon);  James H Jett (Albuquerque, New Mexico);  Steven W Graves (San Jan Pueblo, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Gregory R Goddard (Los Alamos, New Mexico);  Gregory Kaduchak (Eugene, Oregon);  James H Jett (Albuquerque, New Mexico);  Steven W Graves (San Jan Pueblo, New Mexico)
ABSTRACT Method and system for uniformly spacing particles in a flowing system comprising suspending particles in an elongated fluid filled cavity; exposing said cavity to an axial acoustic standing wave field, wherein said axial acoustic standing wave field drives said particles to nodal and anti-nodal positions along the center axis of said cavity to result in uniformly spaced particles; and focusing said particles to the center axis of said cavity.
FILED Thursday, August 09, 2012
APPL NO 13/570605
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1404 (20130101) Original (OR) Class
G01N 15/1484 (20130101)
G01N 2015/142 (20130101)
G01N 2015/149 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932551 Kim et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Dohyun Kim (Rocky Point, New York);  David Alexoff (Westhampton, New York);  Sung Won Kim (Port Jefferson, New York);  Jacob Hooker (Belmont, Massachusetts);  Richard A. Ferrieri (Patchogue, New York)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Dohyun Kim (Rocky Point, New York);  David Alexoff (Westhampton, New York);  Sung Won Kim (Port Jefferson, New York);  Jacob Hooker (Belmont, Massachusetts);  Richard A. Ferrieri (Patchogue, New York)
ABSTRACT A method for providing 11C-labeled cyanides from 11C labeled oxides in a target gas stream retrieved from an irradiated high pressure gaseous target containing O2 is provided, wherein 11C labeled oxides are reduced with H2 in the presence of a nickel catalyst under a pressure and a temperature sufficient to form a product stream comprising at least about 95% 11CH4 , the 11CH4 is then combined with an excess of NH3 in a carrier/reaction stream flowing at an accelerated velocity and the combined 11CH4 carrier/reaction stream is then contacted with a platinum (Pt) catalyst particulate supported on a substantially-chemically-nonreactive heat-stable support at a temperature of at least about 900 ° C., whereby a product stream comprising at least about 60%H11CN is provided in less than 10 minutes from retrieval of the 11C labeled oxide.
FILED Monday, August 13, 2012
APPL NO 13/584033
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Ammonia; Cyanogen; Compounds Thereof
C01C 3/0212 (20130101)
C01C 3/0216 (20130101)
C01C 3/0229 (20130101) Original (OR) Class

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932576 Mayfield
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Stephen P. Mayfield (Cardiff, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Stephen P. Mayfield (Cardiff, California)
ABSTRACT Methods and compositions are disclosed to engineer chloroplast comprising heterologous mammalian genes via a direct replacement of chloroplast Photosystem II (PSII) reaction center protein coding regions to achieve expression of recombinant protein above 5% of total protein. When algae is used, algal expressed protein is produced predominantly as a soluble protein where the functional activity of the peptide is intact. As the host algae is edible, production of biologics in this organism for oral delivery of proteins/peptides, especially gut active proteins, without purification is disclosed.
FILED Wednesday, January 27, 2010
APPL NO 12/695101
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932768 Park et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Sang-Ho Park (Woodridge, Illinois);  Khalil Amine (Downers Grove, Illinois)
ABSTRACT A method of manufacture an article of a cathode (positive electrode) material for lithium batteries. The cathode material is a lithium molybdenum composite transition metal oxide material and is prepared by mixing in a solid state an intermediate molybdenum composite transition metal oxide and a lithium source. The mixture is thermally treated to obtain the lithium molybdenum composite transition metal oxide cathode material.
FILED Tuesday, April 16, 2013
APPL NO 13/863955
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 45/006 (20130101)
C01G 45/1228 (20130101)
C01G 51/006 (20130101)
C01G 51/50 (20130101)
C01G 53/006 (20130101)
C01G 53/50 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/52 (20130101)
C01P 2002/72 (20130101)
C01P 2002/77 (20130101)
C01P 2004/03 (20130101)
C01P 2004/32 (20130101)
C01P 2004/61 (20130101)
C01P 2006/11 (20130101)
C01P 2006/40 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101) Original (OR) Class
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 10/052 (20130101)
H01M 10/056 (20130101)
H01M 10/0525 (20130101)
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932771 Visco et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Steven J. Visco (Berkeley, California);  Vitaliy Nimon (San Francisco, California);  Lutgard C. De Jonghe (Lafayette, California);  Yury Volfkovich (Moscow, Russian Federation);  Daniil Bograchev (Moscow, Russian Federation)
ASSIGNEE(S) PolyPlus Battery Company (Berkeley, California)
INVENTOR(S) Steven J. Visco (Berkeley, California);  Vitaliy Nimon (San Francisco, California);  Lutgard C. De Jonghe (Lafayette, California);  Yury Volfkovich (Moscow, Russian Federation);  Daniil Bograchev (Moscow, Russian Federation)
ABSTRACT Electrochemical energy storage devices, such as alkali metal-oxygen battery cells (e.g., non-aqueous lithium-air cells), have a cathode architecture with a porous structure and pore composition that is tailored to improve cell performance, especially as it pertains to one or more of the discharge/charge rate, cycle life, and delivered ampere-hour capacity. A porous cathode architecture having a pore volume that is derived from pores of varying radii wherein the pore size distribution is tailored as a function of the architecture thickness is one way to achieve one or more of the aforementioned cell performance improvements.
FILED Friday, June 15, 2012
APPL NO 13/525128
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/404
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932781 Yang et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Lei Yang (Atlanta, Georgia);  Zhe Cheng (Wilmington, Delaware);  Ze Liu (Atlanta, Georgia);  Meilin Liu (Alpharetta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Lei Yang (Atlanta, Georgia);  Zhe Cheng (Wilmington, Delaware);  Ze Liu (Atlanta, Georgia);  Meilin Liu (Alpharetta, Georgia)
ABSTRACT Embodiments of the present disclosure include chemical compositions, structures, anodes, cathodes, electrolytes for solid oxide fuel cells, solid oxide fuel cells, fuel cells, fuel cell membranes, separation membranes, catalytic membranes, sensors, coatings for electrolytes, electrodes, membranes, and catalysts, and the like, are disclosed.
FILED Friday, October 30, 2009
APPL NO 12/609179
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 25/006 (20130101)
C01G 53/006 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/34 (20130101)
C01P 2002/52 (20130101)
C01P 2002/72 (20130101)
C01P 2002/82 (20130101)
C01P 2002/85 (20130101)
C01P 2002/88 (20130101)
C01P 2006/40 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/50 (20130101)
C04B 35/6262 (20130101)
C04B 2235/3201 (20130101)
C04B 2235/3215 (20130101)
C04B 2235/3224 (20130101)
C04B 2235/3225 (20130101)
C04B 2235/3229 (20130101)
C04B 2235/3244 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/12 (20130101) Original (OR) Class

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/9008 (20130101)
H01M 4/9033 (20130101)
H01M 8/1246 (20130101)
H01M 2008/1293 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/522 (20130101)
Y02E 60/525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932859 Tsien et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Roger Y. Tsien (La Jolla, California);  Lei Wang (San Diego, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Roger Y. Tsien (La Jolla, California);  Lei Wang (San Diego, California)
ABSTRACT Methods using somatic hypermutation (SHM) for producing polypeptide and nucleic acid variants, and nucleic acids encoding such polypeptide variants are disclosed. Such variants may have desired properties. Also disclosed are novel polypeptides, such as improved fluorescent proteins, produced by the novel methods, and nucleic acids, vectors, and host cells comprising such vectors.
FILED Wednesday, May 21, 2008
APPL NO 12/124888
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932875 Cooks et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Robert Graham Cooks (West Lafayette, Indiana);  Guangtao Li (Carmel, Indiana);  Xin Li (West Lafayette, Indiana);  Zheng Ouyang (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Guangtao Li (Carmel, Indiana);  Xin Li (West Lafayette, Indiana);  Zheng Ouyang (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for sample analysis. In certain embodiments, the invention provides a system for analyzing a sample that includes a probe including a material connected to a high voltage source, a device for generating a heated gas, and a mass analyzer.
FILED Thursday, December 29, 2011
APPL NO 13/977758
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/42 (20130101) Original (OR) Class
H01J 49/0431 (20130101)
H01J 49/0459 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932898 Christoforo et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Mark Greyson Christoforo (Stanford, California);  Saahil Mehra (Saratoga, California);  Alberto Salleo (San Francisco, California);  Peter Peumans (Leuven, Belgium)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior Univerity (Palo Alto, California)
INVENTOR(S) Mark Greyson Christoforo (Stanford, California);  Saahil Mehra (Saratoga, California);  Alberto Salleo (San Francisco, California);  Peter Peumans (Leuven, Belgium)
ABSTRACT In one embodiment, a method is provided for fabrication of a semitransparent conductive mesh. A first solution having conductive nanowires suspended therein and a second solution having nanoparticles suspended therein are sprayed toward a substrate, the spraying forming a mist. The mist is processed, while on the substrate, to provide a semitransparent conductive material in the form of a mesh having the conductive nanowires and nanoparticles. The nanoparticles are configured and arranged to direct light passing through the mesh. Connections between the nanowires provide conductivity through the mesh.
FILED Friday, January 13, 2012
APPL NO 13/350511
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0025 (20130101)
B22F 1/0025 (20130101)
B22F 1/0059 (20130101)
B22F 3/002 (20130101)
B22F 3/002 (20130101)
B22F 3/24 (20130101)
B22F 7/004 (20130101)
B22F 7/004 (20130101)
B22F 2003/248 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Alloys
C22C 32/0021 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 4/121 (20130101)
C23C 24/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/1884 (20130101)
H01L 31/022466 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932940 Wang et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) Deli Wang (San Diego, California);  Cesare Soci (Singapore, Singapore);  Xinyu Bao (Mountain View, California);  Wei Wei (Pasadena, California);  Yi Jing (La Jolla, California);  Ke Sun (La Jolla, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Deli Wang (San Diego, California);  Cesare Soci (Singapore, Singapore);  Xinyu Bao (Mountain View, California);  Wei Wei (Pasadena, California);  Yi Jing (La Jolla, California);  Ke Sun (La Jolla, California)
ABSTRACT Embodiments of the invention provide a method for direct heteroepitaxial growth of vertical III-V semiconductor nanowires on a silicon substrate. The silicon substrate is etched to substantially completely remove native oxide. It is promptly placed in a reaction chamber. The substrate is heated and maintained at a growth temperature. Group III-V precursors are flowed for a growth time. Preferred embodiment vertical Group III-V nanowires on silicon have a core-shell structure, which provides a radial homojunction or heterojunction. A doped nanowire core is surrounded by a shell with complementary doping. Such can provide high optical absorption due to the long optical path in the axial direction of the vertical nanowires, while reducing considerably the distance over which carriers must diffuse before being collected in the radial direction. Alloy composition can also be varied. Radial and axial homojunctions and heterojunctions can be realized. Embodiments provide for flexible Group III-V nanowire structures. An array of Group III-V nanowire structures is embedded in polymer. A fabrication method forms the vertical nanowires on a substrate, e.g., a silicon substrate. Preferably, the nanowires are formed by the preferred methods for fabrication of Group III-V nanowires on silicon. Devices can be formed with core/shell and core/multi-shell nanowires and the devices are released from the substrate upon which the nanowires were formed to create a flexible structure that includes an array of vertical nanowires embedded in polymer.
FILED Wednesday, October 28, 2009
APPL NO 13/126381
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0262 (20130101) Original (OR) Class
H01L 21/02381 (20130101)
H01L 21/02543 (20130101)
H01L 21/02546 (20130101)
H01L 21/02549 (20130101)
H01L 21/02573 (20130101)
H01L 21/02603 (20130101)
H01L 21/02636 (20130101)
H01L 27/0605 (20130101)
H01L 29/20 (20130101)
H01L 29/068 (20130101)
H01L 29/88 (20130101)
H01L 29/205 (20130101)
H01L 29/267 (20130101)
H01L 29/0665 (20130101)
H01L 29/0673 (20130101)
H01L 29/0676 (20130101)
H01L 29/7784 (20130101)
H01L 31/074 (20130101)
H01L 31/03529 (20130101)
H01L 31/035281 (20130101)
H01L 33/08 (20130101)
H01L 33/20 (20130101)
H01L 33/32 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 438/938 (20130101)
Y10S 438/967 (20130101)
Y10S 438/974 (20130101)
Y10S 977/762 (20130101)
Y10S 977/763 (20130101)
Y10S 977/764 (20130101)
Y10S 977/765 (20130101)
Y10S 977/813 (20130101)
Y10S 977/815 (20130101)
Y10S 977/819 (20130101)
Y10S 977/825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933143 Boydston et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Andrew J. Boydston (Seattle, Washington);  Robert H. Grubbs (South Pasadena, California);  Chris Daeffler (Pasadena, California);  Nebojsa Momcilovic (Pasadena, California)
ABSTRACT Compositions and methods for adjustable lenses are provided. In some embodiments, the lenses contain a lens matrix material, a masking compound, and a prepolymer. The lens matrix material provides structure to the lens. The masking compound is capable of blocking polymerization or crosslinking of the prepolymer, until photoisomerization of the compound is triggered, and the compound is converted from a first isomer to a second isomer having a different absorption profile. The prepolymer is a composition that can undergo a polymerization or crosslinking reaction upon photoinitiation to alter one or more of the properties of the lenses.
FILED Tuesday, November 05, 2013
APPL NO 14/071947
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/14 (20130101)
A61F 2/1624 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0051 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 22/14 (20130101)
C08F 120/14 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/38 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/24 (20130101)
C08J 3/28 (20130101)
C08J 2333/00 (20130101)

Compositions of Macromolecular Compounds
C08L 33/08 (20130101)
C08L 33/10 (20130101)
C08L 83/04 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/043 (20130101)
G02B 1/043 (20130101)
G02B 1/043 (20130101)
G02B 1/043 (20130101)

Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses
G02C 7/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933210 Lu et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Yi Lu (Champaign, Illinois);  Yu Xiang (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Yi Lu (Champaign, Illinois);  Yu Xiang (Urbana, Illinois)
ABSTRACT A general methodology to design label-free fluorescent functional nucleic acid sensors using a vacant site approach and an abasic site approach is described. In one example, a method for designing label-free fluorescent functional nucleic acid sensors (e.g., those that include a DNAzyme, aptamer or aptazyme) that have a tunable dynamic range through the introduction of an abasic site (e.g., dSpacer) or a vacant site into the functional nucleic acids. Also provided is a general method for designing label-free fluorescent aptamer sensors based on the regulation of malachite green (MG) fluorescence. A general method for designing label-free fluorescent catalytic and molecular beacons (CAMBs) is also provided. The methods demonstrated here can be used to design many other label-free fluorescent sensors to detect a wide range of analytes. Sensors and methods of using the disclosed sensors are also provided.
FILED Thursday, October 06, 2011
APPL NO 13/267414
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933237 Hong et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Kunlun Hong (Knoxville, Tennessee);  Jun Yang (Oak Ridge, Tennessee);  Peter V. Bonnesen (Knoxville, Tennessee)
ABSTRACT Methods for synthesizing deuterated vinylpyridine compounds of the Formula (1), wherein the method includes: (i) deuterating an acyl pyridine of the Formula (2) in the presence of a metal catalyst and D2O, wherein the metal catalyst is active for hydrogen exchange in water, to produce a deuterated acyl compound of Formula (3); (ii) reducing the compound of Formula (3) with a deuterated reducing agent to convert the acyl group to an alcohol group, and (iii) dehydrating the compound produced in step (ii) with a dehydrating agent to afford the vinylpyridine compound of Formula (1). The resulting deuterated vinylpyridine compounds are also described.
FILED Thursday, January 16, 2014
APPL NO 14/156916
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 213/16 (20130101) Original (OR) Class
C07D 213/127 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933401 Reed
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Bryan W. Reed (Livermore, California)
ABSTRACT A scanning transmission electron microscopy (STEM) system is disclosed. The system may make use of an electron beam scanning system configured to generate a plurality of electron beam scans over substantially an entire sample, with each scan varying in electron-illumination intensity over a course of the scan. A signal acquisition system may be used for obtaining at least one of an image, a diffraction pattern, or a spectrum from the scans, the image, diffraction pattern, or spectrum representing only information from at least one of a select subplurality or linear combination of all pixel locations comprising the image. A dataset may be produced from the information. A subsystem may be used for mathematically analyzing the dataset to predict actual information that would have been produced by each pixel location of the image.
FILED Friday, October 25, 2013
APPL NO 14/063319
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/28 (20130101) Original (OR) Class
H01J 2237/2802 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933436 Forrest et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Stephen R. Forrest (Ann Arbor, Michigan);  Richard R. Lunt (Cambridge, Massachusetts)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Stephen R. Forrest (Ann Arbor, Michigan);  Richard R. Lunt (Cambridge, Massachusetts)
ABSTRACT An ordered multilayer crystalline organic thin film structure is formed by depositing at least two layers of thin film crystalline organic materials successively wherein the at least two thin film layers are selected to have their surface energies within ±50% of each other, and preferably within ±15% of each other, whereby every thin film layer within the multilayer crystalline organic thin film structure exhibit a quasi-epitaxial relationship with the adjacent crystalline organic thin film.
FILED Monday, April 11, 2011
APPL NO 13/084233
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 23/02 (20130101)
C30B 29/54 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0008 (20130101)
H01L 51/0053 (20130101)
H01L 51/56 (20130101)
H01L 51/4246 (20130101)
H01L 51/5004 (20130101)
H01L 51/5012 (20130101) Original (OR) Class
H01L 2227/326 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933596 Stalford
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Harold Stalford (Norman, Oklahoma)
ASSIGNEE(S) MicroZeus, LLC (Dallas, Texas)
INVENTOR(S) Harold Stalford (Norman, Oklahoma)
ABSTRACT A micro rotary machine may include a micro actuator and a micro shaft coupled to the micro actuator. The micro shaft comprises a horizontal shaft and is operable to be rotated by the micro actuator. A micro tool is coupled to the micro shaft and is operable to perform work in response to motion of the micro shaft.
FILED Monday, April 16, 2012
APPL NO 13/448039
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0024 (20130101)
B81B 2201/031 (20130101)
B81B 2201/034 (20130101)
B81B 2201/037 (20130101)
B81B 2201/051 (20130101)

Dynamo-electric Machines
H02K 7/00 (20130101)

Electric Machines Not Otherwise Provided for
H02N 1/002 (20130101)
H02N 10/00 (20130101) Original (OR) Class
H02N 11/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934058 Chou et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Jason Chou (Walnut Creek, California);  Corey V. Bennett (Livermore, California);  Vince Hernandez (Brisbane, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Jason Chou (Walnut Creek, California);  Corey V. Bennett (Livermore, California);  Vince Hernandez (Brisbane, California)
ABSTRACT A signal digitizing system and method based on analog-to-time optical mapping, optically maps amplitude information of an analog signal of interest first into wavelength information using an amplitude tunable filter (ATF) to impress spectral changes induced by the amplitude of the analog signal onto a carrier signal, i.e. a train of optical pulses, and next from wavelength information to temporal information using a dispersive element so that temporal information representing the amplitude information is encoded in the time domain in the carrier signal. Optical-to-electrical conversion of the optical pulses into voltage waveforms and subsequently digitizing the voltage waveforms into a digital image enables the temporal information to be resolved and quantized in the time domain. The digital image may them be digital signal processed to digitally reconstruct the analog signal based on the temporal information with high fidelity.
FILED Wednesday, November 27, 2013
APPL NO 14/092763
ART UNIT 2422 — Cable and Television
CURRENT CPC
Transmission
H04B 10/67 (20130101) Original (OR) Class
H04B 10/69 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934097 Rushford
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Michael Charles Rushford (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Michael Charles Rushford (Livermore, California)
ABSTRACT An optical instrument aligns an optical beam without the need for physical intervention of the instrument within the apparatus or platforms from which the trajectory of the beam to be ascertained. The alignment apparatus and method enable the desired function to be realized without the placement of physical apertures or sensors directly in the path of the beam through the system whose spatial position and slope is to be sought. An image plane provides the observer with a pair of well-defined images that are indicative of the beam centering and pointing alignment parameters. The optical alignment can be realized without the need for referencing to an external or fixed set of coordinates or fiducials. The instrument can therefore service situations where adverse environments would otherwise prohibit the use of such instruments, including regions of high radiation, high temperature, vacuum and/or cryogenic atmospheres.
FILED Friday, January 29, 2010
APPL NO 12/696777
ART UNIT 2886 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/272 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934210 Denis et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Ronald J. Denis (Camas, Washington);  Nathanael J. Makowski (Vancouver, Washington)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Ronald J. Denis (Camas, Washington);  Nathanael J. Makowski (Vancouver, Washington)
ABSTRACT A method for demagnetizing comprising positioning a core within the electromagnetic field generated by a first winding until the generated first electrical current is not substantially increasing, thereby determining a saturation current. A second voltage, having the opposite polarity, is then applied across the first winding until the generated second electrical current is approximately equal to the magnitude of the determined saturation current. The maximum magnetic flux within the core is then determined using the voltage across said first winding and the second current. A third voltage, having the opposite polarity, is then applied across the first winding until the core has a magnetic flux equal to approximately half of the determined maximum magnetic flux within the core.
FILED Thursday, June 28, 2012
APPL NO 13/535637
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/149
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934511 Woodruff et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) Steven D. Woodruff (Morgantown, West Virginia);  Dustin L. Mcintyre (Washington, Pennsylvania)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Steven D. Woodruff (Morgantown, West Virginia);  Dustin L. Mcintyre (Washington, Pennsylvania)
ABSTRACT A method and device for providing a laser interlock having a first optical source, a first beam splitter, a second optical source, a detector, an interlock control system, and a means for producing dangerous optical energy. The first beam splitter is optically connected to the first optical source, the first detector and the second optical source. The detector is connected to the interlock control system. The interlock control system is connected to the means for producing dangerous optical energy and configured to terminate its optical energy production upon the detection of optical energy at the detector from the second optical source below a predetermined detector threshold. The second optical source produces an optical energy in response to optical energy from the first optical source. The optical energy from the second optical source has a different wavelength, polarization, modulation or combination thereof from the optical energy of the first optical source.
FILED Wednesday, September 11, 2013
APPL NO 14/023822
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934608 Barty
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Christopher P. Barty (Hayward, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Christopher P. Barty (Hayward, California)
ABSTRACT New configurations of lasers and electron beams efficiently and robustly produce high flux beams of bright, tunable, polarized quasi-monoenergetic x-rays and gamma-rays via laser-Compton scattering. Specifically, the use of long-duration, pulsed lasers and closely-spaced, low-charge and low emittance bunches of electron beams increase the spectral flux of the Compton-scattered x-rays and gamma rays, increase efficiency of the laser-electron interaction and significantly reduce the overall complexity of Compton based light sources.
FILED Wednesday, July 18, 2012
APPL NO 13/552610
ART UNIT 2882 — Optics
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 5/0008 (20130101) Original (OR) Class

X-ray Technique
H05G 2/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934965 Rogers et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
APPLICANT(S) John Rogers (Champaign, Illinois);  Dae-Hyeong Kim (Champaign, Illinois);  Brian Litt (Bala Cynwyd, Pennsylvania);  Jonathan Viventi (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) John Rogers (Champaign, Illinois);  Dae-Hyeong Kim (Champaign, Illinois);  Brian Litt (Bala Cynwyd, Pennsylvania);  Jonathan Viventi (Philadelphia, Pennsylvania)
ABSTRACT Provided are methods and devices for interfacing with brain tissue, specifically for monitoring and/or actuation of spatio-temporal electrical waveforms. The device is conformable having a high electrode density and high spatial and temporal resolution. A conformable substrate supports a conformable electronic circuit and a barrier layer. Electrodes are positioned to provide electrical contact with a brain tissue. A controller monitors or actuates the electrodes, thereby interfacing with the brain tissue. In an aspect, methods are provided to monitor or actuate spatio-temporal electrical waveform over large brain surface areas by any of the devices disclosed herein.
FILED Friday, June 01, 2012
APPL NO 13/486726
ART UNIT 3739 — Optical Communications
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0478 (20130101) Original (OR) Class
A61B 5/04001 (20130101)
A61B 5/4094 (20130101)
A61B 5/6868 (20130101)
A61B 2562/046 (20130101)
A61B 2562/125 (20130101)
A61B 2562/164 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/20 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0531 (20130101)
A61N 1/3606 (20130101)
A61N 1/36017 (20130101)
A61N 1/36025 (20130101)
A61N 5/0601 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08932524 Farquharson et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Stuart Farquharson (Meriden, Connecticut);  Paul Maksymiuk (Albuquerque, New Mexico);  Chetan S. Shende (Vernon, Connecticut)
ASSIGNEE(S) Real-Time Analyzers, Inc. (Middletown, Connecticut)
INVENTOR(S) Stuart Farquharson (Meriden, Connecticut);  Paul Maksymiuk (Albuquerque, New Mexico);  Chetan S. Shende (Vernon, Connecticut)
ABSTRACT A stationary medium is employed both to separate chemicals from a sample solution and also to generate surface-enhanced Raman scattering, so that spectral analysis of the separated analyte chemical can be performed. Applied driving force causes the sample to flow into the stationary medium and to distribute therethrough, thereby causing rapid separation of the analyte chemical, and surface-enhanced Raman scattered radiation is quickly detected, at a plurality of locations along a flow path defined by the stationary medium, for ultimate analysis.
FILED Friday, September 02, 2011
APPL NO 13/199601
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/40 (20130101)
G01N 21/63 (20130101)
G01N 21/63 (20130101)
G01N 21/658 (20130101) Original (OR) Class
G01N 30/74 (20130101)
G01N 30/74 (20130101)
G01N 30/78 (20130101)
G01N 30/78 (20130101)
G01N 30/6082 (20130101)
G01N 30/6095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932671 Advincula
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Rigoberto Advincula (Friendswood, Texas)
ASSIGNEE(S) The University of Houston System (Houston, Texas)
INVENTOR(S) Rigoberto Advincula (Friendswood, Texas)
ABSTRACT Nano-composites include a graphite material such as nanotubes or graphene sheets and a partial or complete coating of a polymer including sufficient π-conjugated moieties to interact with surfaces of the graphite material. The polymers may also include electropolymerizable or oxidatively polymerizable moieties so the films may be crosslinked. The films may be used to form layers on substrates or patterned layers on substrates.
FILED Thursday, December 01, 2011
APPL NO 13/309111
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/82 (20130101)
C01P 2002/84 (20130101)
C01P 2002/88 (20130101)
C01P 2004/13 (20130101)
C01P 2004/133 (20130101)

Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black;
C09C 1/46 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932807 Decho et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Emerging Frontiers (EF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Alan W. Decho (Columbia, South Carolina);  Tomohiro Kawaguchi (Columbia, South Carolina);  Yung-pin Chen (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Alan W. Decho (Columbia, South Carolina);  Tomohiro Kawaguchi (Columbia, South Carolina);  Yung-pin Chen (Columbia, South Carolina)
ABSTRACT A cell-lysate extract based assay reagent for detecting quorum sensing signals is generally provided, along with methods of making and using the same. The assay reagent generally includes a cell-lysate extract formed from a biosensor bacterium (e.g., Agrobacterium tumefaciens NTL4 (pCF218)(pCF372)) and a detecting substrate (e.g., an absorbance-based or luminescence-based substrate). The cell-lysate extract can be prepared by (1) disrupting the cell membranes of the biosensor bacterium to release the cellular components into a solution, (2) centrifuging the resulting solution, and (3) removing the resulting supernatant solution.
FILED Tuesday, October 01, 2013
APPL NO 14/043052
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/34 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/78 (20130101)
G01N 21/6428 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932875 Cooks et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Robert Graham Cooks (West Lafayette, Indiana);  Guangtao Li (Carmel, Indiana);  Xin Li (West Lafayette, Indiana);  Zheng Ouyang (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Guangtao Li (Carmel, Indiana);  Xin Li (West Lafayette, Indiana);  Zheng Ouyang (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for sample analysis. In certain embodiments, the invention provides a system for analyzing a sample that includes a probe including a material connected to a high voltage source, a device for generating a heated gas, and a mass analyzer.
FILED Thursday, December 29, 2011
APPL NO 13/977758
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/42 (20130101) Original (OR) Class
H01J 49/0431 (20130101)
H01J 49/0459 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932940 Wang et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Electrical and Communications Systems (ECS)
APPLICANT(S) Deli Wang (San Diego, California);  Cesare Soci (Singapore, Singapore);  Xinyu Bao (Mountain View, California);  Wei Wei (Pasadena, California);  Yi Jing (La Jolla, California);  Ke Sun (La Jolla, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Deli Wang (San Diego, California);  Cesare Soci (Singapore, Singapore);  Xinyu Bao (Mountain View, California);  Wei Wei (Pasadena, California);  Yi Jing (La Jolla, California);  Ke Sun (La Jolla, California)
ABSTRACT Embodiments of the invention provide a method for direct heteroepitaxial growth of vertical III-V semiconductor nanowires on a silicon substrate. The silicon substrate is etched to substantially completely remove native oxide. It is promptly placed in a reaction chamber. The substrate is heated and maintained at a growth temperature. Group III-V precursors are flowed for a growth time. Preferred embodiment vertical Group III-V nanowires on silicon have a core-shell structure, which provides a radial homojunction or heterojunction. A doped nanowire core is surrounded by a shell with complementary doping. Such can provide high optical absorption due to the long optical path in the axial direction of the vertical nanowires, while reducing considerably the distance over which carriers must diffuse before being collected in the radial direction. Alloy composition can also be varied. Radial and axial homojunctions and heterojunctions can be realized. Embodiments provide for flexible Group III-V nanowire structures. An array of Group III-V nanowire structures is embedded in polymer. A fabrication method forms the vertical nanowires on a substrate, e.g., a silicon substrate. Preferably, the nanowires are formed by the preferred methods for fabrication of Group III-V nanowires on silicon. Devices can be formed with core/shell and core/multi-shell nanowires and the devices are released from the substrate upon which the nanowires were formed to create a flexible structure that includes an array of vertical nanowires embedded in polymer.
FILED Wednesday, October 28, 2009
APPL NO 13/126381
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0262 (20130101) Original (OR) Class
H01L 21/02381 (20130101)
H01L 21/02543 (20130101)
H01L 21/02546 (20130101)
H01L 21/02549 (20130101)
H01L 21/02573 (20130101)
H01L 21/02603 (20130101)
H01L 21/02636 (20130101)
H01L 27/0605 (20130101)
H01L 29/20 (20130101)
H01L 29/068 (20130101)
H01L 29/88 (20130101)
H01L 29/205 (20130101)
H01L 29/267 (20130101)
H01L 29/0665 (20130101)
H01L 29/0673 (20130101)
H01L 29/0676 (20130101)
H01L 29/7784 (20130101)
H01L 31/074 (20130101)
H01L 31/03529 (20130101)
H01L 31/035281 (20130101)
H01L 33/08 (20130101)
H01L 33/20 (20130101)
H01L 33/32 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 438/938 (20130101)
Y10S 438/967 (20130101)
Y10S 438/974 (20130101)
Y10S 977/762 (20130101)
Y10S 977/763 (20130101)
Y10S 977/764 (20130101)
Y10S 977/765 (20130101)
Y10S 977/813 (20130101)
Y10S 977/815 (20130101)
Y10S 977/819 (20130101)
Y10S 977/825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933203 Rome et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Leonard H. Rome (Tarzana, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Raval-Fernandes Sujna (West Hills, California);  Phoebe L. Stewart (Brentwood, Tennessee)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Leonard H. Rome (Tarzana, California);  Valerie A. Kickhoefer (Sherman Oaks, California);  Raval-Fernandes Sujna (West Hills, California);  Phoebe L. Stewart (Brentwood, Tennessee)
ABSTRACT A method of using vaults as carrier molecules to deliver one or more than one substance to an organism, or to a specific tissue or to specific cells, or to an environmental medium. A vault-like particle. A method of preventing damage by one or more than one substance to an organism, to a specific tissue, to specific cells, or to an environmental medium, by sequestering the one or more than one substance within a vault-like particle. A method of delivering one or more than one substance or a sensor to an organism, to a specific tissue, to specific cells, or to an environmental medium. According to another embodiment of the present invention, there is provided a method of making vault-like particles, and making vault-like particles comprising one or more than one substance, or one or more than one sensor.
FILED Wednesday, October 15, 2008
APPL NO 12/252200
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 47/48776 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 14/47 (20130101) Original (OR) Class
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/88 (20130101)
C12N 2810/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933210 Lu et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Yi Lu (Champaign, Illinois);  Yu Xiang (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Yi Lu (Champaign, Illinois);  Yu Xiang (Urbana, Illinois)
ABSTRACT A general methodology to design label-free fluorescent functional nucleic acid sensors using a vacant site approach and an abasic site approach is described. In one example, a method for designing label-free fluorescent functional nucleic acid sensors (e.g., those that include a DNAzyme, aptamer or aptazyme) that have a tunable dynamic range through the introduction of an abasic site (e.g., dSpacer) or a vacant site into the functional nucleic acids. Also provided is a general method for designing label-free fluorescent aptamer sensors based on the regulation of malachite green (MG) fluorescence. A general method for designing label-free fluorescent catalytic and molecular beacons (CAMBs) is also provided. The methods demonstrated here can be used to design many other label-free fluorescent sensors to detect a wide range of analytes. Sensors and methods of using the disclosed sensors are also provided.
FILED Thursday, October 06, 2011
APPL NO 13/267414
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933298 Jahn et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Margaret Jahn (Lansing, New York);  Jason Cavatorta (Davis, California);  Inhwa Yeam (Seoul, South Korea)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Margaret Jahn (Lansing, New York);  Jason Cavatorta (Davis, California);  Inhwa Yeam (Seoul, South Korea)
ABSTRACT The present invention relates to a nucleic acid molecule encoding a mutant form of wild-type translation initiation factor eIF4E, which has an amino acid sequence of SEQ ID NO: 1, wherein the mutant form imparts resistance to Potato virus Y and has a mutation with respect to the wild-type amino acid sequence of SEQ ID NO: 1 selected from the group consisting of: (1) any one or more of I70N, I70E, L82R, and D112N and (2) any one or more of L48F, S68K, A77D, and M109I. Nucleic acid constructs, expression vectors, cells, plants, and plant seeds containing the nucleic acid molecule of the present invention, are also disclosed, as are methods of imparting resistance to Potato virus Y to plants.
FILED Thursday, October 22, 2009
APPL NO 13/125429
ART UNIT 1638 — Organic Chemistry
CURRENT CPC
Peptides
C07K 14/415 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8283 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933496 Bulovic et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Vladimir Bulovic (Lexington, Massachusetts);  Jeffrey H. Lang (Sudbury, Massachusetts);  Sarah Paydavosi (Tehran, Iran);  Annie I-Jen Wang (Cambridge, Massachusetts);  Trisha L. Andrew (Cambridge, Massachusetts);  Apoorva Murarka (Jaipur, India);  Farnaz Niroui (Ontario, Canada);  Frank Yaul (Bellevue, Washington);  Jeffrey C. Grossman (Brookline, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Vladimir Bulovic (Lexington, Massachusetts);  Jeffrey H. Lang (Sudbury, Massachusetts);  Sarah Paydavosi (Tehran, Iran);  Annie I-Jen Wang (Cambridge, Massachusetts);  Trisha L. Andrew (Cambridge, Massachusetts);  Apoorva Murarka (Jaipur, India);  Farnaz Niroui (Ontario, Canada);  Frank Yaul (Bellevue, Washington);  Jeffrey C. Grossman (Brookline, Massachusetts)
ABSTRACT A method and apparatus for making analog and digital electronics which includes a composite including a squishable material doped with conductive particles. A microelectromechanical systems (MEMS) device has a channel made from the composite, where the channel forms a primary conduction path for the device. Upon applied voltage, capacitive actuators squeeze the composite, causing it to become conductive. The squishable device includes a control electrode, and a composite electrically and mechanically connected to two terminal electrodes. By applying a voltage to the control electrode relative to a first terminal electrode, an electric field is developed between the control electrode and the first terminal electrode. This electric field results in an attractive force between the control electrode and the first terminal electrode, which compresses the composite and enables electric control of the electron conduction from the first terminal electrode through the channel to the second terminal electrode.
FILED Monday, November 07, 2011
APPL NO 13/291016
ART UNIT 2896 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 45/00 (20130101) Original (OR) Class

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/742 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934096 Herzinger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Craig M. Herzinger (Lincoln, Nebraska);  Mathias M. Schubert (Lincoln, Nebraska);  Tino Hofmann (Lincoln, Nebraska);  Martin M. Liphardt (Lincoln, Nebraska);  John A. Woollam (Lincoln, Nebraska)
ASSIGNEE(S) University of Nebraska Board of Regents (Lincoln, Nebraska);  J.A. Woollam Co., Inc. (Lincoln, Nebraska)
INVENTOR(S) Craig M. Herzinger (Lincoln, Nebraska);  Mathias M. Schubert (Lincoln, Nebraska);  Tino Hofmann (Lincoln, Nebraska);  Martin M. Liphardt (Lincoln, Nebraska);  John A. Woollam (Lincoln, Nebraska)
ABSTRACT The present invention relates to ellipsometer and polarimeter systems, and more particularly is an ellipsometer or polarimeter or the like system which operates in a frequency range between 300 GHz or lower and extending to higher than at least 1 Tera-hertz (THz), and preferably through the Infra-red (IR) range up to, and higher than 100 THz, including: a source such as a backward wave oscillator; a Smith-Purcell cell; a free electron laser, or an FTIR source and a solid state device; and a detector such as a Golay cell; a bolometer or a solid state detector;
and preferably including at least one odd-bounce polarization state image rotating system, and optionally including a polarizer, at least one compensator and/or modulator, in addition to an analyzer.
FILED Friday, May 11, 2012
APPL NO 13/506707
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 4/04 (20130101) Original (OR) Class
G01J 5/20 (20130101)
G01J 5/42 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/211 (20130101)
G01N 21/3581 (20130101)
G01N 2021/3595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934965 Rogers et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
APPLICANT(S) John Rogers (Champaign, Illinois);  Dae-Hyeong Kim (Champaign, Illinois);  Brian Litt (Bala Cynwyd, Pennsylvania);  Jonathan Viventi (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) John Rogers (Champaign, Illinois);  Dae-Hyeong Kim (Champaign, Illinois);  Brian Litt (Bala Cynwyd, Pennsylvania);  Jonathan Viventi (Philadelphia, Pennsylvania)
ABSTRACT Provided are methods and devices for interfacing with brain tissue, specifically for monitoring and/or actuation of spatio-temporal electrical waveforms. The device is conformable having a high electrode density and high spatial and temporal resolution. A conformable substrate supports a conformable electronic circuit and a barrier layer. Electrodes are positioned to provide electrical contact with a brain tissue. A controller monitors or actuates the electrodes, thereby interfacing with the brain tissue. In an aspect, methods are provided to monitor or actuate spatio-temporal electrical waveform over large brain surface areas by any of the devices disclosed herein.
FILED Friday, June 01, 2012
APPL NO 13/486726
ART UNIT 3739 — Optical Communications
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0478 (20130101) Original (OR) Class
A61B 5/04001 (20130101)
A61B 5/4094 (20130101)
A61B 5/6868 (20130101)
A61B 2562/046 (20130101)
A61B 2562/125 (20130101)
A61B 2562/164 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/20 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0531 (20130101)
A61N 1/3606 (20130101)
A61N 1/36017 (20130101)
A61N 1/36025 (20130101)
A61N 5/0601 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935098 Di Carlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
National Science Foundation (NSF)
APPLICANT(S) Dino Di Carlo (Los Angeles, California);  Daniel R. Gossett (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dino Di Carlo (Los Angeles, California);  Daniel R. Gossett (Los Angeles, California);  Henry T. K. Tse (San Francisco, California)
ABSTRACT A system is disclosed that enables the automated measurement of cellular mechanical parameters at high throughputs. The microfluidic device uses intersecting flows to create an extensional flow region where the cells undergo controlled stretching. Cells are focused into streamlines prior to entering the extensional flow region. In the extensional region, each cell's deformation is measured with an imaging device. Automated image analysis extracts a range of independent biomechanical parameters from the images. These may include cell size, deformability, and circularity. The single cell data that is obtained may then be used to in a variety of ways. Scatter density plots of deformability and circularity may be developed and displayed for the user. Mechanical parameters such as deformability and circularity may be gated or thresholded to identify certain cells of interest or sub-populations of interest. Similarly, the mechanical data obtained using the device may be used as cell signatures.
FILED Friday, September 16, 2011
APPL NO 13/823109
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1459 (20130101)
G01N 15/1484 (20130101)
G01N 33/574 (20130101)
G01N 2015/1495 (20130101)

Electric Digital Data Processing
G06F 19/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935291 Chen
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Chaomei Chen (Villanova, Pennsylvania)
ABSTRACT A system and method are provided for automatically generating systematic reviews of received information in a field of science and technology, such as scientific literature, where the systematic review includes a systematic review of a research field in the scientific literature. The method includes the steps of constructing a time series networks of words, passages, documents, and citations and/or co-citations within received information into a synthesized network, decomposing the networks into clusters of fields or topics, performing part-of-speech tagging of text within the received information to provide tagged text, constructing semantic structures of concepts and/or assertions extracted from the source text, generating citation-based and content-based summaries of the clusters of fields or topics and the semantic structures, and generating structured narratives of the clusters of fields or topics and the summaries of the generated semantic structures. Narratives of the citation-based and content-based summaries are merged into a systematic review.
FILED Tuesday, October 01, 2013
APPL NO 14/043446
ART UNIT 2163 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 17/30598 (20130101) Original (OR) Class
G06F 17/30734 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935506 Gopalan
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Kartik Gopalan (Vestal, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Binghamton, New York)
INVENTOR(S) Kartik Gopalan (Vestal, New York)
ABSTRACT MemX provides a distributed system that virtualizes cluster-wide memory to support data-intensive and large memory workloads in virtual machines (VMs), and provides benefits in virtualized settings: (1) VM workloads that access large datasets can perform low-latency I/O over virtualized cluster-wide memory; (2) VMs can transparently execute very large memory applications that require more memory than physical DRAM present in the host machine; (3) reduces the effective memory usage of the cluster by de-duplicating pages that have identical content; (4) existing applications do not require any modifications to benefit from MemX such as the use of special APIs, libraries, recompilation, or relinking; and (5) supports live migration of large-footprint VMs by eliminating the need to migrate part of their memory footprint resident on other nodes. Detailed evaluations show that large dataset applications and multiple concurrent VMs achieve significant performance improvements using MemX compared against virtualized local and iSCSI disks.
FILED Thursday, March 22, 2012
APPL NO 13/427110
ART UNIT 2189 — Computer Networks
CURRENT CPC
Electrical computers and digital processing systems: Memory
711/202
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 08931142 Langley et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Patrick T. Langley (Laurel, Maryland);  Fazle E. Siddique (Baltimore, Maryland)
ABSTRACT An article, such as, but not limited to, a cable strap to wrap, support, or secure one or more wires or cables, is formed by cyclically heating and cooling and/or irradiating an article formed of a static dissipative ethylene tetrafluoroethylen (ETFE) resin, to reduce an electrical resistivity and/or to increase a tensile strength of the article.
FILED Monday, July 01, 2013
APPL NO 13/932201
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 71/02 (20130101)
B29C 71/04 (20130101)

Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 63/1027 (20130101) Original (OR) Class
B65D 63/1063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08931546 Zaffetti
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S) Mark A. Zaffetti (Suffield, Connecticut)
ASSIGNEE(S) Hamilton Sundstrand Space Sytems International, Inc. (Windsor Locks, Connecticut)
INVENTOR(S) Mark A. Zaffetti (Suffield, Connecticut)
ABSTRACT A structural cold plate assembly includes a support structure including first and second opposite sides supporting corresponding cold plates and an insert. The insert defines a portion of a fluid passage through the support structure and secures the cold plate to the support structure.
FILED Monday, March 29, 2010
APPL NO 12/748576
ART UNIT 3744 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 3/12 (20130101) Original (OR) Class
F28F 9/0246 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/20254 (20130101)
H05K 7/20272 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932047 Wollen
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Mark A. Wollen (Murieta, California)
ASSIGNEE(S) Innovative Engineering Solutions, Inc. (San Diego, California)
INVENTOR(S) Mark A. Wollen (Murieta, California)
ABSTRACT A propellant flow actuated piezoelectric igniter device using one or more hammer balls retained by one or more magnets, or other retaining method, until sufficient fluid pressure is achieved to release and accelerate the hammer ball, such that it impacts a piezoelectric crystal to produce an ignition spark. Certain preferred embodiments provide a means for repetitively capturing and releasing the hammer ball after it impacts one or more piezoelectric crystals, thereby oscillating and producing multiple, repetitive ignition sparks. Furthermore, an embodiment is presented for which oscillation of the hammer ball and repetitive impact to the piezoelectric crystal is maintained without the need for a magnet or other retaining mechanism to achieve this oscillating impact process.
FILED Monday, October 18, 2010
APPL NO 12/906360
ART UNIT 3743 — Optics
CURRENT CPC
Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines
F02P 3/12 (20130101)

Ignition; Extinguishing-devices
F23Q 3/002 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/183 (20130101) Original (OR) Class
H02N 2/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932683 Kohlman et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Lee W. Kohlman (Cleveland, Ohio);  Gary D. Roberts (Wadsworth, Ohio)
ABSTRACT Method and apparatus for enhancing the durability as well as the strength and stiffness of prepreg fiber tows of the sort used in composite materials are disclosed. The method involves adhering electrospun fibers onto the surface of such composite materials as filament-wound composite objects and the surface of prepreg fiber tows of the sort that are subsequently used in the production of composite materials of the filament-wound, woven, and braided sorts. The apparatus performs the methods described herein.
FILED Friday, June 14, 2013
APPL NO 13/918333
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 11/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933666 Schwartz et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) Paul D. Schwartz (Arnold, Maryland);  Mark N. Martin (Ellicott City, Maryland);  Lewis M. Roufberg (Clarksville, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Paul D. Schwartz (Arnold, Maryland);  Mark N. Martin (Ellicott City, Maryland);  Lewis M. Roufberg (Clarksville, Maryland)
ABSTRACT A method of equalizing charge states of individual cells in a battery includes measuring a previous cell voltage for each cell, measuring a previous shunt current for each cell, calculating, based on the previous cell voltage and the previous shunt current, an adjusted cell voltage for each cell, determining a lowest adjusted cell voltage from among the calculated adjusted cell voltages, and calculating a new shunt current for each cell.
FILED Tuesday, July 12, 2011
APPL NO 13/181132
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/0016 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933789 Fink et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronauties and Space Administration (Washington, District of Columbia)
INVENTOR(S) Patrick W. Fink (Missouri City, Texas);  Gregory Y. Lin (Friendswood, Texas);  Timothy F. Kennedy (Sugar Land, Texas);  Phong H. Ngo (Friendswood, Texas);  Diane Byerly (Seabrook, Texas)
ABSTRACT Methods, apparatuses and systems for radio frequency identification (RFID)-enabled information collection are disclosed, including an enclosure, a collector coupled to the enclosure, an interrogator, a processor, and one or more RFID field sensors, each having an individual identification, disposed within the enclosure. In operation, the interrogator transmits an incident signal to the collector, causing the collector to generate an electromagnetic field within the enclosure. The electromagnetic field is affected by one or more influences. RFID sensors respond to the electromagnetic field by transmitting reflected signals containing the individual identifications of the responding RFID sensors to the interrogator. The interrogator receives the reflected signals, measures one or more returned signal strength indications (“RSSI”) of the reflected signals and sends the RSSI measurements and identification of the responding RFID sensors to the processor to determine one or more facts about the influences. Other embodiments are also described.
FILED Friday, March 08, 2013
APPL NO 13/790591
ART UNIT 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC
Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 23/2845 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/0723 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933863 Devereaux et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Innovation Management Sciences, LLC (Los Altos, California)
ASSIGNEE(S)
INVENTOR(S) Ann Devereaux (Tujunga, California);  Thomas Jedrey (Pasadena, California);  Martin Agan (Pasadena, California)
ABSTRACT A portable unit is for video communication to select a user name in a user name network. A transceiver wirelessly accesses a communication network through a wireless connection to a general purpose node coupled to the communication network. A user interface can receive user input to log on to a user name network through the communication network. The user name network has a plurality of user names, at least one of the plurality of user names is associated with a remote portable unit, logged on to the user name network and available for video communication.
FILED Sunday, February 23, 2014
APPL NO 14/187315
ART UNIT 2692 — Selective Visual Display Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101)

Image Data Processing or Generation, in General
G06T 19/006 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 17/02 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/04 (20130101)
H04L 67/12 (20130101)

Pictorial Communication, e.g Television
H04N 7/147 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 08932047 Wollen
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Mark A. Wollen (Murieta, California)
ASSIGNEE(S) Innovative Engineering Solutions, Inc. (San Diego, California)
INVENTOR(S) Mark A. Wollen (Murieta, California)
ABSTRACT A propellant flow actuated piezoelectric igniter device using one or more hammer balls retained by one or more magnets, or other retaining method, until sufficient fluid pressure is achieved to release and accelerate the hammer ball, such that it impacts a piezoelectric crystal to produce an ignition spark. Certain preferred embodiments provide a means for repetitively capturing and releasing the hammer ball after it impacts one or more piezoelectric crystals, thereby oscillating and producing multiple, repetitive ignition sparks. Furthermore, an embodiment is presented for which oscillation of the hammer ball and repetitive impact to the piezoelectric crystal is maintained without the need for a magnet or other retaining mechanism to achieve this oscillating impact process.
FILED Monday, October 18, 2010
APPL NO 12/906360
ART UNIT 3743 — Optics
CURRENT CPC
Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines
F02P 3/12 (20130101)

Ignition; Extinguishing-devices
F23Q 3/002 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/183 (20130101) Original (OR) Class
H02N 2/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08932199 Berka et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Advanced Brain Monitoring, Inc. (Carlsbad, California)
ASSIGNEE(S) Advanced Brain Monitoring, Inc. (Carlsbad, California)
INVENTOR(S) Christine Berka (Carlsbad, California);  Djordje Popovic (Carlsbad, California);  Dan Levendowski (Carlsbad, California);  Gene Davis (Carlsbad, California);  Catherine McConnell (Carlsbad, California);  Matthew A. Yanagi (Carlsbad, California)
ABSTRACT Sleep mask for reducing sleep inertia. In an embodiment, the sleep mask comprises a foam layer having a shape that covers both of a human subject's eyes so as to attenuate ambient light. Visual stimulation element(s), configured to emit light, are positioned between the foam layer and the subject's eyes. In addition, a plurality of sensors positioned on the forehead of the subject collect electroencephalogram (EEG), electrooculogram (EOG), and electromyogram (EMG) signals. A soft exterior cover houses the foam layer, the visual stimulation element(s), and the sensors. The sleep mask further comprises processor(s) that determine and record each sleep stage of the subject, determine when to wake the subject, and, when it is determined to wake the subject, control the visual stimulation element(s) to wake the subject using emitted light.
FILED Monday, June 23, 2014
APPL NO 14/312345
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0476 (20130101)
A61B 5/0488 (20130101)
A61B 5/0496 (20130101)
A61B 5/4812 (20130101)
A61B 5/4836 (20130101)
A61B 5/6803 (20130101)
A61B 5/7475 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/02 (20130101) Original (OR) Class
A61M 2021/0022 (20130101)
A61M 2021/0027 (20130101)
A61M 2021/0044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933197 Stemmer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Willem P. Stemmer (Los Gatos, California);  Volker Schellenberger (Palo Alto, California)
ASSIGNEE(S) Amunix Operating Inc. (Mountain View, California)
INVENTOR(S) Willem P. Stemmer (Los Gatos, California);  Volker Schellenberger (Palo Alto, California)
ABSTRACT The present invention relates to biologically active polypeptides linked to one or more accessory polypeptides. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.
FILED Friday, August 15, 2008
APPL NO 12/228859
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934096 Herzinger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Craig M. Herzinger (Lincoln, Nebraska);  Mathias M. Schubert (Lincoln, Nebraska);  Tino Hofmann (Lincoln, Nebraska);  Martin M. Liphardt (Lincoln, Nebraska);  John A. Woollam (Lincoln, Nebraska)
ASSIGNEE(S) University of Nebraska Board of Regents (Lincoln, Nebraska);  J.A. Woollam Co., Inc. (Lincoln, Nebraska)
INVENTOR(S) Craig M. Herzinger (Lincoln, Nebraska);  Mathias M. Schubert (Lincoln, Nebraska);  Tino Hofmann (Lincoln, Nebraska);  Martin M. Liphardt (Lincoln, Nebraska);  John A. Woollam (Lincoln, Nebraska)
ABSTRACT The present invention relates to ellipsometer and polarimeter systems, and more particularly is an ellipsometer or polarimeter or the like system which operates in a frequency range between 300 GHz or lower and extending to higher than at least 1 Tera-hertz (THz), and preferably through the Infra-red (IR) range up to, and higher than 100 THz, including: a source such as a backward wave oscillator; a Smith-Purcell cell; a free electron laser, or an FTIR source and a solid state device; and a detector such as a Golay cell; a bolometer or a solid state detector;
and preferably including at least one odd-bounce polarization state image rotating system, and optionally including a polarizer, at least one compensator and/or modulator, in addition to an analyzer.
FILED Friday, May 11, 2012
APPL NO 13/506707
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 4/04 (20130101) Original (OR) Class
G01J 5/20 (20130101)
G01J 5/42 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/211 (20130101)
G01N 21/3581 (20130101)
G01N 2021/3595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 08931277 Peterson et al.
FUNDED BY
U.S. State Government
State of Oregon
APPLICANT(S) Richard B. Peterson (Corvallis, Oregon);  Robbie Ingram-Goble (Corvallis, Oregon);  Kevin J. Harada (Junction City, Oregon)
ASSIGNEE(S) State of Oregon acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon)
INVENTOR(S) Richard B. Peterson (Corvallis, Oregon);  Robbie Ingram-Goble (Corvallis, Oregon);  Kevin J. Harada (Junction City, Oregon)
ABSTRACT Embodiments of a system for storing and providing electrical energy are disclosed. Also disclosed are embodiments of a system for purifying fluid, as well as embodiments of a system in which energy storage and fluid purification are combined. One disclosed embodiment of the system comprises a latent heat storage device, a sensible heat storage device, a vapor expander/compressor device mechanically coupled to a motor/generator device, a heat-exchanger, and a liquid pressurization and depressurization device. The devices are fluidly coupled in a closed-loop system, and a two-phase working fluid circulates therein. Embodiments of a method for operating the system to store and generate energy also are disclosed. Embodiments of a method for operating the system to purify fluid, as well as embodiments of a method for operating a combined energy storage and fluid purification system are disclosed.
FILED Monday, September 19, 2011
APPL NO 13/236466
ART UNIT 3748 — Static Structures, Supports and Furniture
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/22 (20130101)
C02F 2103/08 (20130101)
C02F 2303/10 (20130101)

Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles
F01K 3/12 (20130101)
F01K 25/08 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 17/00 (20130101) Original (OR) Class
F28D 20/02 (20130101)
F28D 20/0056 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/142 (20130101)
Y02E 60/145 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08933129 Abramson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
U.S. State Government
State of Oregon
APPLICANT(S) Jonathan Abramson (Portland, Oregon);  Robert Strongin (Portland, Oregon)
ASSIGNEE(S) State of Oregon by and through the State Board of Higher Education on behalf of Portland State University (Portland, Oregon)
INVENTOR(S) Jonathan Abramson (Portland, Oregon);  Robert Strongin (Portland, Oregon)
ABSTRACT The present teachings provide compounds of Formulae I and II: and pharmaceutically acceptable salts, hydrates, complexes, esters, and prodrugs thereof, wherein R1, R1′, R2, R2′, R3, R3′, and X are as defined herein. The present teachings also provide methods of making the compounds of formulae I and II, and methods of treating RyR-associated conditions, disorders, and diseases that include administering a therapeutically effective amount of a compound of formula I or II to a subject in need thereof. In addition, the present teachings relate to methods of reducing the open probability of a ryanodine receptor, and methods of reducing Ca2+ release across a ryanodine receptor (e.g., into the cytoplasm of a cell), by contacting a compound of formula I or II with a ryanodine receptor.
FILED Thursday, April 15, 2010
APPL NO 13/264055
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/554 (20130101)

Heterocyclic Compounds
C07D 417/06 (20130101) Original (OR) Class
C07D 417/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US PP25223 Finn
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Chad E Finn (Corvallis, Oregon)
ABSTRACT This invention relates to new and distinct cultivar of strawberry plant named ‘Sweet Sunrise’. The new cultivar is primarily characterized by its early ripening and its medium-large, conical fruit that have outstanding processing characteristics including deep red internal and external color, sweet flavor, and very easy calyx removal, as well as vigorous, productive plants that are tolerant to biotic and abiotic stress.
FILED Tuesday, January 22, 2013
APPL NO 13/694950
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/208
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 08932363 Tsougarakis et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Advanced Technology Program (NIST-ATP)
APPLICANT(S) Konstantinos Tsougarakis (Mountain View, California);  Daniel Steines (Palo Alto, California);  Bhaskar Rao Vissa (San Jose, California);  Philipp Lang (Lexington, Massachusetts);  Barry J. Linder (Danville, California)
ASSIGNEE(S) ConforMIS, Inc. (Bedford, Massachusetts)
INVENTOR(S) Konstantinos Tsougarakis (Mountain View, California);  Daniel Steines (Palo Alto, California);  Bhaskar Rao Vissa (San Jose, California);  Philipp Lang (Lexington, Massachusetts);  Barry J. Linder (Danville, California)
ABSTRACT The present invention relates to methods for determining meniscal size and shape for use in designing therapies for the treatment of various joint diseases. The invention uses an image of a joint that is processed for analysis. Analysis can include, for example, generating a thickness map, a cartilage curve, or a point cloud. This information is used to determine the extent of the cartilage defect or damage and to design an appropriate therapy, including, for example, an implant. Adjustments to the designed therapy are made to account for the materials used.
FILED Friday, November 07, 2003
APPL NO 10/704208
ART UNIT 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1075 (20130101)
A61B 5/4514 (20130101)
A61B 5/4528 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/32 (20130101)
A61F 2/34 (20130101)
A61F 2/36 (20130101)
A61F 2/38 (20130101)
A61F 2/40 (20130101)
A61F 2/44 (20130101)
A61F 2/3804 (20130101)
A61F 2/4202 (20130101)
A61F 2/4241 (20130101)
A61F 2/4261 (20130101)
A61F 2/30756 (20130101)
A61F 2/30942 (20130101)
A61F 2002/30133 (20130101)
A61F 2002/30894 (20130101)
A61F 2002/30943 (20130101)
A61F 2002/30948 (20130101)
A61F 2002/30952 (20130101)
A61F 2230/0015 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 623/911 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 08935189 Tyson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Interior (DOI)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Mabry W. Tyson (Los Altos, California);  Douglas E. Appelt (Palo Alto, California);  Min Yin (San Jose, California);  William Jarrold (Davis, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Mabry W. Tyson (Los Altos, California);  Douglas E. Appelt (Palo Alto, California);  Min Yin (San Jose, California);  William Jarrold (Davis, California)
ABSTRACT A non-transitory computer readable storage medium includes instructions to collect explicit feedback from a user regarding user content preferences. Multiple data sources are monitored. Topics associated with the multiple data sources are classified. The importance of the topics to the user is characterized. Content is delivered to the user when a selected topic exceeds an importance threshold for the user. Implicit feedback from the user that characterizes refined user content preferences is tracked. The instructions to characterize the importance of topics evaluates the explicit feedback and the implicit feedback.
FILED Friday, May 27, 2011
APPL NO 13/118226
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/30997 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 30/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 08933832 Kelly et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Michael Kelly (North Reading, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S) The Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Michael Kelly (North Reading, Massachusetts);  Daniel Mooney (Dracut, Massachusetts);  Curtis Colonero (Shrewsbury, Massachusetts);  Robert Berger (Lexington, Massachusetts);  Lawrence Candell (Arlington, Massachusetts)
ABSTRACT Autonomously operating analog to digital converters are formed into a two dimensional array. The array may incorporate digital signal processing functionality. Such an array is particularly well-suited for operation as a readout integrated circuit and, in combination with a sensor array, forms a digital focal plane array.
FILED Thursday, April 12, 2012
APPL NO 13/445433
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 1/60 (20130101)
H03M 1/145 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Reconnaissance Office (NRO) 

US 08934741 Chen et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Reconnaissance Office (NRO)
APPLICANT(S) Baoquan Chen (Bothell, Washington);  Hui Chen (Kirkland, Washington);  Raluca Dinu (Redmond, Washington);  Diyun Huang (Watertown, Massachusetts);  Bing Li (Bothell, Washington);  Eric Miller (Seattle, Washington);  Danliang Jin (Bothell, Washington);  Christopher A. Wiklof (Everett, Washington);  Guomin Yu (Bothell, Washington)
ASSIGNEE(S) Brphotonics Produtos Optoelectronicos LTDA (Sao Paulo, Brazil)
INVENTOR(S) Baoquan Chen (Bothell, Washington);  Hui Chen (Kirkland, Washington);  Raluca Dinu (Redmond, Washington);  Diyun Huang (Watertown, Massachusetts);  Bing Li (Bothell, Washington);  Eric Miller (Seattle, Washington);  Danliang Jin (Bothell, Washington);  Christopher A. Wiklof (Everett, Washington);  Guomin Yu (Bothell, Washington)
ABSTRACT An integrated circuit is configured for optical communication via an optical polymer stack located on top of the integrated circuit. The optical polymer stack may include one or more electro-optic polymer devices including an electro-optic polymer. The electro-optic polymer may include a host polymer and a second order nonlinear chromomophore, the host polymer and the chromophore both including aryl groups configured to interact with one another to provide enhanced thermal and/or temporal stability.
FILED Wednesday, December 08, 2010
APPL NO 12/963479
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/1221 (20130101) Original (OR) Class
G02B 6/12004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 08935248 Atkins et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) C. Scot Atkins (Chantilly, Virginia);  Joseph Conway (Annandale, Virginia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) C. Scot Atkins (Chantilly, Virginia);  Joseph Conway (Annandale, Virginia)
ABSTRACT A method, system, and computer program for processing records is disclosed. The records are associated with record sets. Record sets are associated with processor sets, which include one or more processors. Records are routed to associated processor sets for processing, based on the record set associated with the record. Records are processed on processors in the processor sets. Furthermore, various localized affinities can be established. Process affinity can link server processes with processor sets. Cache affinity can link database caches with processor sets. Data affinity can link incoming data to processor sets.
FILED Friday, April 08, 2011
APPL NO 13/083396
ART UNIT 2159 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 17/30445 (20130101) Original (OR) Class
G06F 17/30463 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08933382 Dolphin
FUNDED BY
APPLICANT(S) Andrew E. Dolphin (Tucson, Arizona)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Andrew E. Dolphin (Tucson, Arizona)
ABSTRACT A missile guidance system is configured to estimate a time to go, the time to go comprising an amount of time until a missile would reach a closest point of approach to a target. The guidance system is also configured to estimate a zero-effort miss distance along a zero-effort miss vector, the zero-effort miss distance comprising a distance by which the missile would miss the target if the missile performs no future maneuvers. The guidance system is also configured to determine a tolerance for the zero-effort miss distance, the tolerance being a function of the time to go. The guidance system is further configured to modify a course of the missile by adjusting an expenditure of propellant such that the estimated zero-effort miss distance in excess of the tolerance is removed from future consideration.
FILED Thursday, March 31, 2011
APPL NO 13/076690
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 15/01 (20130101) Original (OR) Class

Systems for Controlling or Regulating Non-electric Variables
G05D 1/12 (20130101)
G05D 1/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08934776 Steenson, Jr. et al.
FUNDED BY
APPLICANT(S) James H. Steenson, Jr. (New Boston, New Hampshire);  Derek P. Janiak (Manchester, New Hampshire);  Benjamin W. Brown (Hollis, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) James H. Steenson, Jr. (New Boston, New Hampshire);  Derek P. Janiak (Manchester, New Hampshire);  Benjamin W. Brown (Hollis, New Hampshire)
ABSTRACT A plurality of optical transmission sources provide data communication from a transmitting module to a common detector cooperative with a receiving module, the modules being subject to relative rotation about a shared axis. The detector can be located on the shared axis, each of the sources directing a beam onto the detector regardless of relative module orientation, and/or the light can be diffused, so that it is detected regardless of source and detector placement and relative module orientations. Transmissions can be distinguished according to synchronized timing, differing optical frequencies, differing baud rates, and/or differing circular polarizations. The detector can split the light into a plurality of beams which pass through different optical filters and are thereby distinguished. Cut-off circuits can prevent failed sources from transmitting. A diffused second light source and a second plurality of detectors can provide reverse communication from the receiving module to the transmitting module.
FILED Tuesday, April 05, 2011
APPL NO 13/377992
ART UNIT 2637 — Optical Communications
CURRENT CPC
Transmission
H04B 10/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08935107 Adamovsky et al.
FUNDED BY
APPLICANT(S) Grigory Adamovsky (Solon, Ohio);  Roger P Tokars (Cleveland, Ohio)
ASSIGNEE(S) The United States of America as Represented by the Adminstrator of National Aeronautics and Space Adminstration (Washington, District of Columbia)
INVENTOR(S) Grigory Adamovsky (Solon, Ohio);  Roger P Tokars (Cleveland, Ohio)
ABSTRACT A compact shock sensing system and method that employ a light sheet generator that can be used either as a solo aerodynamic shock detector or in a combination with a scanning mode shock sensor is disclosed. This shock sensing system and method can be used to detect and track unstable and travelling shocks in high speed aerodynamic flows, such as those found in supersonic inlets.
FILED Friday, February 18, 2011
APPL NO 13/030342
ART UNIT 2865 — Printing/Measuring and Testing
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/26 (20130101)

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/74 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, January 13, 2015.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2015/fedinvent-patents-20150113.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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