FedInvent™ Patents

Patent Details for Tuesday, June 02, 2015 

This page was updated on Monday, March 27, 2023 at 04:17 AM GMT

Department of Health and Human Services (HHS) 

US 09043994 Stern et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Patrick Stern (Cambridge, Massachusetts);  Richard Hynes (Winchester, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Patrick Stern (Cambridge, Massachusetts);  Richard Hynes (Winchester, Massachusetts)
ABSTRACT The present invention relates to vectors, compositions and methods for conditional, Cre-lox regulated, RNA interference. The vectors allow for spatial and temporal control of miRNA expression in vivo.
FILED Wednesday, March 12, 2008
APPL NO 12/076001
ART UNIT 1674 — SELECT * FROM codes_techcenter;
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101) Original (OR) Class
A01K 2207/05 (20130101)
A01K 2217/058 (20130101)
A01K 2217/206 (20130101)
A01K 2227/105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8509 (20130101)
C12N 2800/30 (20130101)
C12N 2840/007 (20130101)
C12N 2840/102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044007 Sadler
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Complementary and Integrative Health (NCCIH)
National Eye Institute (NEI)
APPLICANT(S) Theodore R. Sadler (Minneapolis, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Theodore R. Sadler (Minneapolis, Minnesota)
ABSTRACT The present invention discloses a method for storing and preserving previously sectioned, snap-frozen, and desiccated biological tissue samples at ambient conditions. Also disclosed are devices and systems for ambient storage of biological tissue sections, and methods for forming said devices.
FILED Thursday, October 08, 2009
APPL NO 12/576168
ART UNIT 1775 — SELECT * FROM codes_techcenter;
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/00 (20130101) Original (OR) Class
A01N 1/0273 (20130101)
A01N 1/0278 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/508 (20130101)
B01L 2300/105 (20130101)
B01L 2300/0809 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/30 (20130101)
G01N 1/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044140 Foster et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Thomas H. Foster (Rochester, New York);  William J. Cottrell (Dallas, Texas);  Chad Bigelow (Somerville, Massachusetts);  Allan R. Oseroff (Buffalo, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Thomas H. Foster (Rochester, New York);  William J. Cottrell (Dallas, Texas);  Chad Bigelow (Somerville, Massachusetts);  Allan R. Oseroff (Buffalo, New York)
ABSTRACT An instrument for photodynamic therapy applies treatment light from a dye laser, white light, and ultraviolet fluorescence excitation light from an LED onto a lesion and surrounding areas in a time-multiplexed manner. The reflected white light is analyzed in a spectrometer to determine a correction for the dynamic optical spectral properties of the patient's tissue. Light emitted by fluorescence from the lesion and the surrounding areas is analyzed in another spectrometer, and the results are corrected in a computer, using the correction. An optical switch has been developed for the instrument, using a bistable solenoid and a sled.
FILED Thursday, June 30, 2005
APPL NO 11/631121
ART UNIT 3769 — SELECT * FROM codes_techcenter;
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0059 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)
A61N 5/0601 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044159 Sanders et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Joan E. Sanders (Sammamish, Washington);  Timothy R. Myers (Seattle, Washington);  Daniel S. Harrison (Kirkland, Washington);  Katheryn J. Allyn (Seattle, Washington);  Ellen L. Lee (Corvallis, Oregon);  Daniel C. Abrahamson (Seattle, Washington);  Kirk Beach (Seattle, Washington);  Santosh Zachariah (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Joan E. Sanders (Sammamish, Washington);  Timothy R. Myers (Seattle, Washington);  Daniel S. Harrison (Kirkland, Washington);  Katheryn J. Allyn (Seattle, Washington);  Ellen L. Lee (Corvallis, Oregon);  Daniel C. Abrahamson (Seattle, Washington);  Kirk Beach (Seattle, Washington);  Santosh Zachariah (Seattle, Washington)
ABSTRACT Changes in the volume of residual limbs on which prosthetic sockets are worn can be measured based on bioimpedance measurements along one or more segments of the limb. A current at an appropriate frequency (e.g., in the range from 1 kHz to 1 MHz) is injected at two current electrodes that contact the skin of the residual limb. The voltage at the voltage electrodes disposed between the current electrodes is measured and using an appropriate model, the change in the segmented volume of the limb can be determined during periods of different activity and at different times during the day. This information can be used for assessing the fit of the socket and can also provide a feedback signal for automatically controlling volume management devices, to ensure a more comfortable fit when the volume of the limb is changing.
FILED Friday, January 27, 2012
APPL NO 13/360525
ART UNIT 3766 — SELECT * FROM codes_techcenter;
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0535 (20130101) Original (OR) Class
A61B 5/1073 (20130101)
A61B 5/6833 (20130101)
A61B 2562/164 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)
A61F 2/80 (20130101)
A61F 2/7843 (20130101)
A61F 2002/704 (20130101)
A61F 2002/5024 (20130101)
A61F 2002/5026 (20130101)
A61F 2002/5027 (20130101)
A61F 2002/5036 (20130101)
A61F 2002/5052 (20130101)
A61F 2002/7615 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044392 Gellman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
APPLICANT(S) Samuel H. Gellman (Madison, Wisconsin);  Shannon S. Stahl (Madison, Wisconsin);  Brendan P. Mowery (San Marcos, California);  Annelise Barron (Palo Alto, California);  Michelle Dohm (Palos Park, Illinois)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  Northwestern University (Evanston, Illinois)
INVENTOR(S) Samuel H. Gellman (Madison, Wisconsin);  Shannon S. Stahl (Madison, Wisconsin);  Brendan P. Mowery (San Marcos, California);  Annelise Barron (Palo Alto, California);  Michelle Dohm (Palos Park, Illinois)
ABSTRACT Non-natural oligomers have recently shown promise as functional analogues of lung surfactant proteins Band C (SP-B and SP-C), two helical and amphiphilic proteins that are clitical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restlicted to step-by-step, sequence-specific synthesis, which results in discrete oligomers that are intended to manifest specific structural attributes. Presented herein an alternative approach to SP-R mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. These materials, members of the nylon-3 family, arc prepared by ling-opening polymelization of 13-lactams. The best of the nylon-3 polymers display promising in vitro surfactant activities in a mixed lipid film. Pulsating bubble surfactometry data indicate that films containing the most surface-active polymers attain adsorptive and dynamic-cycling properties that surpass those of discrete peptides intended to mimic SP-B.
FILED Thursday, March 17, 2011
APPL NO 13/634576
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0082 (20130101) Original (OR) Class
A61K 47/32 (20130101)

Compositions of Macromolecular Compounds
C08L 77/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044419 Neufeld et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Arthur H. Neufeld (Chicago, Illinois);  Ai Ling Wang (Chicago, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Arthur H. Neufeld (Chicago, Illinois);  Ai Ling Wang (Chicago, Illinois)
ABSTRACT Disclosed are compositions and methods for treating or preventing the formation of drusen in a patient in need thereof. The compositions include an effective amount of at least one polypeptide present in drusen, or an immunogenic fragment or variant thereof that induces an immune response against the polypeptide, together with a pharmaceutical carrier, excipient, or diluent. The compositions are suitable as vaccines for treating or preventing drusen and diseases associated with drusen.
FILED Friday, July 22, 2011
APPL NO 13/188982
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0008 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044420 Dubensky, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Thomas W. Dubensky, Jr. (Piedmont, California);  Scott H. Robbins (Lake Forest Park, Washington)
ASSIGNEE(S) IMMUNE DESIGN CORP. (Seattle, Washington)
INVENTOR(S) Thomas W. Dubensky, Jr. (Piedmont, California);  Scott H. Robbins (Lake Forest Park, Washington)
ABSTRACT Compositions and methods are provided herein for improved dual immunization strategies that induce in a subject an immune response that includes a humoral immune response and cellular immune response, both CD4 and CD8 T lymphocyte immune responses, thereby providing a complete adaptive immune response to one or more antigens. The methods described are therefore useful for treating and/or preventing (i.e., reducing the likelihood or risk of occurrence) different diseases, disorders, and conditions such as cancers and infectious diseases for which induction of both a humoral immune response and cellular immune response is desired and beneficial.
FILED Friday, April 06, 2012
APPL NO 13/441502
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 2039/53 (20130101)
A61K 2039/545 (20130101)
A61K 2039/55566 (20130101)
A61K 2039/55572 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/16634 (20130101)
C12N 2740/15034 (20130101)
C12N 2740/16043 (20130101)
C12N 2810/609 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044424 Bachovchin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Trustees of Tufts College (Boston, Massachusetts);  New England Medical Center Hospitals, Inc. (Boston, Massachusetts);  1149336 Ontario, Inc. (Toronto, Canada)
ASSIGNEE(S) 1149336 Ontario, Inc. (Toronto, Ontario, Canada);  New England Medical Center Hospitals. Inc. (Boston, Massachusetts);  Trustees of Tufts College (Boston, Massachusetts)
INVENTOR(S) William W. Bachovchin (Cambridge, Massachusetts);  Andrew G. Plaut (Lexington, Massachusetts);  Daniel J. Drucker (Toronto, Canada)
ABSTRACT The present invention provides methods for modification and regulation of glucose metabolism by administering to an animal a therapeutically effective amount of an inhibitor of dipeptidylpeptidase IV (DPIV) or a pharmaceutically acceptable salt thereof, where the inhibitor has a Ki for inhibition of DPIV of 10 nM or less; and the inhibitor is administered in an amount sufficient to increase the plasma half-life of glucagon-like peptide 1 (GLP-1) but not sufficient to suppress the immune system of the animal.
FILED Thursday, July 25, 2013
APPL NO 13/951060
ART UNIT 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/69 (20130101)
A61K 31/155 (20130101)
A61K 31/155 (20130101)
A61K 31/401 (20130101)
A61K 31/675 (20130101)
A61K 31/702 (20130101)
A61K 31/702 (20130101)
A61K 31/4025 (20130101)
A61K 38/05 (20131010) Original (OR) Class
A61K 38/55 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044433 Hawiger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Jack J. Hawiger (Nashville, Tennessee);  Ruth Ann Veach (Brentwood, Tennessee);  Jozef Zienkiewicz (Nashville, Tennessee);  Yan Liu (Nashville, Tennessee);  Robert D. Collins (Nashville, Tennessee);  Amy Major (Nashville, Tennessee)
ABSTRACT The present invention relates to compositions and methods for treating diseases associated with dyslipidemia, including hypercholesterolemia, hypertriglyceridemia, steatohepatitis, atherosclerosis, obesity, hyperglycemia, metabolic syndrome, and related aspects of and conditions associated with metabolic syndrome. The compositions and methods disclosed herein are useful for regulating the lipid balance (lipid homeostasis) in a subject. Compositions and methods including a Nuclear Transport Modifier may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease in cholesterol and triglyceride levels in the blood and liver, a decrease in atherosclerotic lesion size, a decrease in body weight and in hyperglycemia, a reduction of fatty liver inflammation, and an improvement in liver function.
FILED Friday, October 05, 2012
APPL NO 14/349918
ART UNIT 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/397 (20130101)
A61K 38/08 (20130101)
A61K 38/12 (20130101)
A61K 38/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044447 Corey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Lawrence Corey (Mercer Island, Washington);  Kerry J. Laing (Seattle, Washington);  Anna Wald (Seattle, Washington);  David M. Koelle (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON (Seattle, Washington);  FRED HUTCHISON CANCER RESEARCH CENTER (Seattle, Washington)
INVENTOR(S) Lawrence Corey (Mercer Island, Washington);  Kerry J. Laing (Seattle, Washington);  Anna Wald (Seattle, Washington);  David M. Koelle (Seattle, Washington)
ABSTRACT The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection, including epitopes confirmed to be recognized by T-cells derived from herpetic lesions. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection.
FILED Saturday, April 03, 2010
APPL NO 13/262833
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 39/00 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 2039/5158 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/16622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044451 Zheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Wei Zheng (Potomac, Maryland);  Juan Jose Marugan (Gaithersburg, Maryland);  Ke Liu (Cambridge, Maryland);  Noel Terrence Southall (Chevy Chase, Maryland);  Christopher P Austin (Potomac, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Wei Zheng (Potomac, Maryland);  Juan Jose Marugan (Gaithersburg, Maryland);  Ke Liu (Cambridge, Maryland);  Noel Terrence Southall (Chevy Chase, Maryland);  Christopher P Austin (Potomac, Maryland)
ABSTRACT This disclosure relates generally to the treatment of lysosomal storage disorders. Specifically, the disclosure relates to a novel use of delta tocopherol in the treatment of diseases and conditions related to lysosomal storage disorders. Included in the present disclosure is a method for the modulation of cholesterol recycling. Further, the disclosure relates to conditions such as Niemann-Pick type C disease, Farber disease, Niemann-Pick type A disease, Wolman disease and Tay Sachs disease. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol. Further included in the present disclosure is a method for treating lysosomal storage disorders comprising the administration of delta tocopherol in combination with cyclodextrin to a patient in need thereof.
FILED Tuesday, July 19, 2011
APPL NO 13/810774
ART UNIT 1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/36 (20130101)
A61K 31/36 (20130101)
A61K 31/355 (20130101) Original (OR) Class
A61K 31/355 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/724 (20130101)
A61K 31/724 (20130101)
A61K 36/185 (20130101)
A61K 36/185 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044454 Grutzendler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Jaime Grutzendler (Chicago, Illinois);  Carson K. Lam (Chicago, Illinois);  Taehwan Yoo (Ann Arbor, Michigan)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Jaime Grutzendler (Chicago, Illinois);  Carson K. Lam (Chicago, Illinois);  Taehwan Yoo (Ann Arbor, Michigan)
ABSTRACT The present invention provides compositions and methods to regulate embolic occlusion of the microvasculature. In particular, the present invention inhibits extravasation of emboli from microvasculature resulting in increased occlusion (e.g., by administering a MMP 2/9 inhibitor locally to a subject).
FILED Thursday, March 10, 2011
APPL NO 13/045265
ART UNIT 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/38 (20130101) Original (OR) Class
A61K 31/575 (20130101)
A61K 31/745 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044457 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Dimiter Dimitrov (Frederick, Maryland);  Yang Feng (Frederick, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Dimiter Dimitrov (Frederick, Maryland);  Yang Feng (Frederick, Maryland)
ABSTRACT The present invention provides antibodies and antibody fragments that specifically recognize and agonize the death receptor 4 (DR4). Also provided in the invention are polynucleotides and vectors that encode such molecules and host cells that harbor the polynucleotides or vectors.
FILED Thursday, June 16, 2011
APPL NO 13/704577
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Peptides
C07K 16/2878 (20130101)
C07K 2317/34 (20130101)
C07K 2317/55 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044458 Wong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Philip C. Wong (Lutherville, Maryland);  Donald L. Price (Columbia, Maryland);  Po-Min Chiang (Tainan, Taiwan)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Philip C. Wong (Lutherville, Maryland);  Donald L. Price (Columbia, Maryland);  Po-Min Chiang (Tainan, Taiwan)
ABSTRACT Described herein are methods for detecting, characterizing, preventing, and treating metabolic diseases, including obesity and obesity-associated disorders such as diabetes.
FILED Tuesday, July 26, 2011
APPL NO 13/816334
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/713 (20130101)
A61K 31/7088 (20130101)
A61K 31/7105 (20130101)
A61K 39/3955 (20130101) Original (OR) Class

Peptides
C07K 14/4702 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/136 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2333/4703 (20130101)
G01N 2800/044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044471 Green et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) Alan I. Green (Hanover, New Hampshire);  David Chau (White River Junction, Vermont)
ASSIGNEE(S)
INVENTOR(S) Alan I. Green (Hanover, New Hampshire);  David Chau (White River Junction, Vermont)
ABSTRACT Methods of treating and or preventing substance abuse/dependence, and alcohol abuse/dependence in particular. Combinations of medications are also disclosed.
FILED Friday, February 01, 2008
APPL NO 12/024950
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/451 (20130101) Original (OR) Class
A61K 31/451 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044474 Byrd et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) John C. Byrd (Columbus, Ohio);  Amy J. Johnson (Columbus, Ohio);  Emilia Mahoney (Columbus, Ohio);  David M. Lucas (Hilliard, Ohio);  Michael R. Grever (Powell, Ohio)
ASSIGNEE(S) The Ohio State University (Columbus, Ohio)
INVENTOR(S) John C. Byrd (Columbus, Ohio);  Amy J. Johnson (Columbus, Ohio);  Emilia Mahoney (Columbus, Ohio);  David M. Lucas (Hilliard, Ohio);  Michael R. Grever (Powell, Ohio)
ABSTRACT A method of (a) treating a lymphoproliferative disease in a subject in need thereof; (b) slowing the progression of lymphoproliferative disease in a subject who has been diagnosed with a lymphoproliferative disease; or (c) preventing or delaying development of a lymphoproliferative disease in a subject who is at risk of developing a lymphoproliferative disease. The method generally comprises administering to the individual an effective amount of a combination therapy comprising: i) at least one autophagy modulating agent, or a derivative, pharmaceutically acceptable salt thereof, or prodrug thereof; and ii) at least one CDK inhibitor agent, or a derivative, pharmaceutically acceptable salt thereof, or prodrug thereof, wherein the i) agent and the ii) agents are administered in amounts sufficient to enhance the cytotoxicity of the combination relative to the CDK inhibitor agent treatment alone.
FILED Monday, November 07, 2011
APPL NO 13/883862
ART UNIT 1674 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/343 (20130101)
A61K 31/453 (20130101)
A61K 31/4706 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 48/005 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57426 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044486 Whittaker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Gary R. Whittaker (Ithaca, New York);  Andrew D. Regan (Athens, Georgia)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Gary R. Whittaker (Ithaca, New York);  Andrew D. Regan (Athens, Georgia)
ABSTRACT Provided is a method for treatment and/or prophylaxis of FIP (feline infectious peritonitis) in cats. The method is performed by administering to a cat a composition comprising a therapeutic and/or prophylactic amount of a cysteine protease inhibitor. The cysteine protease inhibitor can be a selective cathepsin B inhibitor. Also provided is a method for inhibiting FIPV (Feline infectious peritonitis virus) replication. The method comprises contacting a cell infected with FIPV with a cysteine protease inhibitor in an amount effective to inhibit replication of FIPV. It is expected the method will be effective for therapy or prophylaxis of FIP in any species of cat and will be effective against any strain of feline coronavirus.
FILED Thursday, April 02, 2009
APPL NO 12/935967
ART UNIT 1676 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/05 (20130101)
A61K 38/55 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044491 Mayeux et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Philip R. Mayeux (Little Rock, Arkansas);  Joseph H. Holthoff (Little Rock, Arkansas)
ASSIGNEE(S) The Board of Trustees of the University of Arkansas (Little Rock, Alaska)
INVENTOR(S) Philip R. Mayeux (Little Rock, Arkansas);  Joseph H. Holthoff (Little Rock, Arkansas)
ABSTRACT The present invention generally provides methods for using stilbenoid derivatives to improve blood flow and microcirculation.
FILED Wednesday, December 28, 2011
APPL NO 13/339150
ART UNIT 1673 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7034 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044503 Hersh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute on Drug Abuse (NIDA)
Non-Profit Organization (NPO)
Alzheimer\'s Disease and Related Disorders Association, Inc. (ADRDA)
APPLICANT(S) Louis B. Hersh (Lexington, Kentucky);  Hanjun Guan (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) Louis B. Hersh (Lexington, Kentucky);  Hanjun Guan (Lexington, Kentucky)
ABSTRACT Methods for treatment and/or prevention of Alzheimer's disease comprising inactivating peripheral AP in serum to a reduce A(3 in the brain. Methods comprise expression of amyloid peptide inactivating enzyme on bone marrow cells; and coupling of amyloid peptide inactivating enzyme to hematopoietic cells.
FILED Friday, August 26, 2005
APPL NO 11/661274
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 48/00 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/6494 (20130101)
C12N 15/86 (20130101)
C12N 2740/15043 (20130101)
C12N 2830/008 (20130101)
C12N 2830/48 (20130101)

Enzymes
C12Y 304/24011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044509 Heneine et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Walid M. Heneine (Atlanta, Georgia);  Thomas M. Folks (Helotes, Texas);  Robert Janssen (Atlanta, Georgia);  Ronald Otten (Villa Rica, Georgia);  Jose Gerardo Garcia Lerma (Villa Rica, Georgia)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Walid M. Heneine (Atlanta, Georgia);  Thomas M. Folks (Helotes, Texas);  Robert Janssen (Atlanta, Georgia);  Ronald Otten (Villa Rica, Georgia);  Jose Gerardo Garcia Lerma (Villa Rica, Georgia)
ABSTRACT A process is provided for protecting a primate host from a self-replicating infection by an immunodeficiency retrovirus. Protection is achieved by administering to the primate host a combination of a pharmaceutically effective amount of a nucleoside reverse transcriptase inhibitor and a pharmaceutically effective amount of a nucleotide reverse transcriptase inhibitor prior to exposure to the immunodeficiency retrovirus. The administration is effective if provided in a single dose within 24 hours of the exposure. A regime of regular daily doses is also effective in providing protection against an immunodeficiency retrovirus becoming self-replicating after infecting a primate host. A process for controlling retrovirus transmission within a population includes the administration to a subpopulation at high risk for contracting an immunodeficiency retroviral infection the detailed combination prior to sexual exposure to a source of immunodeficiency retrovirus so as to preclude the immunodeficiency retrovirus from becoming self-replicating in a member of the subpopulation.
FILED Wednesday, January 31, 2007
APPL NO 11/669547
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/513 (20130101)
A61K 31/675 (20130101)
A61K 31/675 (20130101)
A61K 31/7072 (20130101)
A61K 31/7072 (20130101)
A61K 45/06 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044510 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Zhou-feng Chen (St. Louis, Missouri);  Yan-gang Sun (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Zhou-feng Chen (St. Louis, Missouri);  Yan-gang Sun (St. Louis, Missouri)
ABSTRACT The present invention encompasses methods and compositions for alleviating pruritis. The compositions may comprise an analgesic agent.
FILED Monday, November 03, 2008
APPL NO 12/740819
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/00 (20130101)
A61K 31/485 (20130101)
A61K 38/168 (20130101)
A61K 45/06 (20130101) Original (OR) Class
A61K 47/10 (20130101)
A61K 47/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044515 Baldwin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Aaron Baldwin (Orange, California);  Kristi Lynn Kiick (Rising Sun, Maryland)
ASSIGNEE(S) UNIVERSITY OF DELAWARE (Newark, Delaware)
INVENTOR(S) Aaron Baldwin (Orange, California);  Kristi Lynn Kiick (Rising Sun, Maryland)
ABSTRACT The present invention is related to compositions which can undergo targeted degradation under certain physiological reducing conditions. The compositions may, for example, be hydrogels in which maleimide-functionalized low molecular weight heparin is cross-linked with various thiol-functionalized polyethylene glycol multi-arm star polymers. Both the gelation and degradation of the hydrogels can be modified by careful selection of the thiol. For example, hydrogels prepared from aryl thiol-maleimide adducts can undergo a retro Michael addition-type reaction, leading to degradation of the composition and release of the bioactive molecule.
FILED Thursday, September 06, 2012
APPL NO 13/605297
ART UNIT 1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48215 (20130101) Original (OR) Class
A61K 47/48784 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044518 Pettit et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
U.S. State Government
State of Arizona
APPLICANT(S) George R. Pettit (Paradise Valley, Arizona);  Fiona Hogan (Gilbert, Arizona);  Steven Toms (Wellington, New Zealand)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) George R. Pettit (Paradise Valley, Arizona);  Fiona Hogan (Gilbert, Arizona);  Steven Toms (Wellington, New Zealand)
ABSTRACT The present invention relates to new auristatin compounds and prodrugs thereof, compositions comprising them and uses thereof.
FILED Thursday, March 29, 2012
APPL NO 14/007743
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/472 (20130101)
A61K 31/472 (20130101)
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 38/00 (20130101)
A61K 38/08 (20130101)
A61K 45/06 (20130101)
A61K 47/48415 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 207/12 (20130101)
C07D 401/12 (20130101)

Peptides
C07K 5/0205 (20130101)
C07K 7/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044530 Ling et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Southwest Research Institute (San Antonio, Texas)
ASSIGNEE(S) SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas)
INVENTOR(S) Jian Ling (Spring Branch, Texas);  Ben Antebi (McKinney, Texas);  Xingguo Cheng (San Antonio, Texas);  Jeffrey N. Harris (San Antonio, Texas)
ABSTRACT The present disclosure is directed at a process to form bone grafting material. One may provide a porous collagen scaffold and insert the scaffold into a perfusion chamber of a perfusion flow system. This may then be followed by continuously providing a mineralization perfusion fluid flow through the scaffold at a flow rate to provide dynamic intrafibrillar mineralization of the scaffold and form a collagen/hydroxyapatite composite scaffold. One may optionally provide the scaffold with bone tissue forming cells and then deliver a perfusion fluid including oxygen and one or more nutrients through the collagen/hydroxyapatite composite scaffold and to the bone tissue forming cells at a flow rate such that the bone tissue forming cells remodel the collagen/hydroxyapatite composite scaffold and form a bone tissue extracellular matrix. The bone tissue extracellular matrix may then be decellularized to form an acellular bone repair scaffold.
FILED Wednesday, December 19, 2012
APPL NO 13/720543
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/46 (20130101) Original (OR) Class
A61L 27/46 (20130101)
A61L 27/56 (20130101)
A61L 27/3821 (20130101)
A61L 2430/02 (20130101)

Compositions of Macromolecular Compounds
C08L 89/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044590 Greenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Second Sight Medical Products, Inc. (San Fernando, California)
ASSIGNEE(S) Second Sight Medical Products, Inc. (Sylmar, California)
INVENTOR(S) Robert J Greenberg (Los Angeles, California);  Jerry Ok (Canyon Country, California);  Jordan Matthew Neysmith (Pasadena, California);  Brian V Mech (Santa Clarita, California);  Neil Hamilton Talbot (La Crescenta, California)
ABSTRACT Polymer materials make useful materials as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision. Regardless of which polymer is used, the basic construction method is the same. A layer of polymer is laid down. A layer of metal is applied to the polymer and patterned to create electrodes and leads for those electrodes. A second layer of polymer is applied over the metal layer and patterned to leave openings for the electrodes, or openings are created later by means such as laser ablation. Hence the array and its supply cable are formed of a single body.
FILED Thursday, August 08, 2013
APPL NO 13/962752
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0543 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044596 Mahadevan-Jansen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Anita Mahadevan-Jansen (Nashville, Tennessee);  Jonathan Cayce (Nashville, Tennessee);  Robert Friedman (Nashville, Tennessee);  Anna Roe (Nashville, Tennessee);  E. Duco Jansen (Nashville, Tennessee);  Mykyta Chernov (Nashville, Tennessee);  Peter E. Konrad (Old Hickory, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Anita Mahadevan-Jansen (Nashville, Tennessee);  Jonathan Cayce (Nashville, Tennessee);  Robert Friedman (Nashville, Tennessee);  Anna Roe (Nashville, Tennessee);  E. Duco Jansen (Nashville, Tennessee);  Mykyta Chernov (Nashville, Tennessee);  Peter E. Konrad (Old Hickory, Tennessee)
ABSTRACT Certain aspects of the present disclosure are directed to a method of applying infrared neural stimulation (INS) to the central nervous system (CNS) of a target. The methods includes applying a pulsed infrared laser at a stimulation site in the CNS; and evoking responses from a region of interest of the CNS that is at or adjacent to the stimulation site by the pulsed infrared laser. In the method, the pulsed infrared laser penetrates a predetermined penetration depth of the stimulation site. Certain aspects of the present disclosure are directed to an apparatus for applying INS to the CNS of a target. The apparatus includes a generator generating a pulsed infrared laser, which penetrates a predetermined penetration depth of a stimulation site to evoke a response from the CNS, and an optical medium adapted for delivering the pulsed infrared laser at the stimulation site of the CNS.
FILED Thursday, May 24, 2012
APPL NO 13/480012
ART UNIT 3769 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0622 (20130101) Original (OR) Class
A61N 2005/063 (20130101)
A61N 2005/067 (20130101)
A61N 2005/0659 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044902 Bowman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Christopher Bowman (Boulder, Colorado);  Brian Adzima (Boulder, Colorado);  Christopher Kloxin (Boulder, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
INVENTOR(S) Christopher Bowman (Boulder, Colorado);  Brian Adzima (Boulder, Colorado);  Christopher Kloxin (Boulder, Colorado)
ABSTRACT The invention includes a composite material comprising magnetic field responsive particles distributed in a reversibly crosslinked polymer, wherein the reversibly crosslinked polymer includes thermally reversible bonds. In one embodiment, exposing the composite material to an electromagnetic field allows for crack-healing, remolding and/or bonding of the material.
FILED Wednesday, November 23, 2011
APPL NO 13/303782
ART UNIT 1768 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 35/0272 (20130101)
B29C 65/76 (20130101)
B29C 65/368 (20130101)
B29C 65/3612 (20130101)
B29C 66/0242 (20130101)
B29C 66/721 (20130101)
B29C 66/919 (20130101)
B29C 66/9192 (20130101)
B29C 66/73756 (20130101)
B29C 66/91216 (20130101)
B29C 66/91315 (20130101)
B29C 66/91411 (20130101)
B29C 66/91445 (20130101)
B29C 66/91651 (20130101)
B29C 66/91921 (20130101)
B29C 73/16 (20130101) Original (OR) Class
B29C 73/18 (20130101)
B29C 2035/0861 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2105/203 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/22 (20130101)
C08K 2003/2251 (20130101)
C08K 2201/01 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 5/06 (20130101)
C09J 2205/31 (20130101)
C09J 2400/226 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045415 Toretsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Jeffrey A. Toretsky (Silver Spring, Maryland);  Aykut Üren (Rockville, Maryland);  Milton Lang Brown (Brookville, Maryland);  Yali Kong (Centreville, Virginia)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Jeffrey A. Toretsky (Silver Spring, Maryland);  Aykut Üren (Rockville, Maryland);  Milton Lang Brown (Brookville, Maryland);  Yali Kong (Centreville, Virginia)
ABSTRACT Peptides and compounds are provided that function as EWS-FLI1 protein inhibitors. The peptides and compounds have utility in the treatment of Ewing's sarcoma family of tumors. Also provided are methods of preparing the compounds and assays for identifying inhibitors of EWS-FLI1 protein.
FILED Tuesday, March 09, 2010
APPL NO 12/720616
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Heterocyclic Compounds
C07D 209/38 (20130101) Original (OR) Class
C07D 401/06 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 7/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045416 Lum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Lawrence Lum (Dallas, Texas);  Michael G. Roth (Dallas, Texas);  Baozhi Chen (Addison, Texas);  Chuo Chen (Dallas, Texas);  Michael E. Dodge (Irving, Texas);  Wei Tang (Beijing, China PRC)
ABSTRACT The present invention generally relates to protein signalling. In particular, compounds that inhibit the Wnt protein signalling pathway are disclosed. Such compounds may be used in the treatment of Wnt protein signalling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.
FILED Wednesday, May 01, 2013
APPL NO 13/875170
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 209/48 (20130101) Original (OR) Class
C07D 209/94 (20130101)
C07D 239/54 (20130101)
C07D 401/10 (20130101)
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 403/10 (20130101)
C07D 413/04 (20130101)
C07D 417/12 (20130101)
C07D 471/04 (20130101)
C07D 519/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045418 Jordan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) SIGA TECHNOLOGIES, INC. (Corvallis, Oregon)
ASSIGNEE(S) SIGA TECHNOLOGIES, INC. (Corvallis, Oregon)
INVENTOR(S) Robert Jordan (Corvallis, Oregon);  Thomas R. Bailey (Phoenixville, Pennsylvania);  Susan R. Rippin (Wilmington, Delaware);  Dongcheng Dai (Corvallis, Oregon)
ABSTRACT Methods of using di, tri, and tetracyclic acylhydrazide derivatives and analogs, as well as pharmaceutical compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the orthopoxvirus.
FILED Thursday, July 03, 2014
APPL NO 14/323587
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4035 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 209/50 (20130101)
C07D 209/56 (20130101)
C07D 209/70 (20130101) Original (OR) Class
C07D 209/76 (20130101)
C07D 209/94 (20130101)
C07D 401/12 (20130101)
C07D 409/12 (20130101)
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045421 Gelb et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Michael H. Gelb (Seattle, Washington);  Frantisek Turecek (Seattle, Washington);  James Bollinger (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Michael H. Gelb (Seattle, Washington);  Frantisek Turecek (Seattle, Washington);  James Bollinger (Seattle, Washington)
ABSTRACT Method and reagent for converting a carboxylic acid to a positively charge amide are described. The method and reagent facilitate positive ion mass spectral analysis of carboxylic acids. The method includes reacting a carboxylic acid with a compound having formula I:
wherein A and B are aromatic rings, ring A includes a quaternized nitrogen and has n additional ring atoms, each additional ring atom optionally substituted with an RA group, and n is an integer from 4 to 10, and ring B includes a carbon atom and has m additional ring atoms, each additional ring atom optionally substituted with an RB group, and m is an integer from 4 to 10. The compound includes at least one RA or RB group, and the at least one RA and RB group is -L-N(Z)H; and X is a counterion.
FILED Friday, April 01, 2011
APPL NO 13/078652
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 213/20 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/88 (20130101)
G01N 33/92 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045442 Mobashery et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Shahriar Mobashery (Notre Dame, Indiana);  Peter I. O'Daniel (Notre Dame, Indiana);  Mayland Chang (Notre Dame, Indiana)
ASSIGNEE(S) University of Notre Dame du Lac (Notre Dame, Indiana)
INVENTOR(S) Shahriar Mobashery (Notre Dame, Indiana);  Peter I. O'Daniel (Notre Dame, Indiana);  Mayland Chang (Notre Dame, Indiana)
ABSTRACT Embodiments of the present invention provide novel antibacterials that target penicillin-binding proteins or other important cellular targets. Methods for inhibiting growth (reproduction, etc.) of bacteria using compounds described herein are also provided. Various embodiments exhibit activity against gram positive bacteria, such as certain strains of Entercoccus and Staphylococcus aureus.
FILED Friday, December 21, 2007
APPL NO 12/680541
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 271/06 (20130101) Original (OR) Class
C07D 413/12 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/65318 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045474 Schiestl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Robert H. Schiestl (Encino, California);  Yelena O. Rivina (Los Angeles, California);  Michael E. Jung (Los Angeles, California);  Robert Damoiseaux (Beverly Hills, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Robert H. Schiestl (Encino, California);  Yelena O. Rivina (Los Angeles, California);  Michael E. Jung (Los Angeles, California);  Robert Damoiseaux (Beverly Hills, California)
ABSTRACT Embodiments of the present invention provide compounds and compositions thereof, which are effective for mitigating tissue damage or lethality induced by an agent, and methods of making and using the same.
FILED Wednesday, August 03, 2011
APPL NO 13/813923
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/381 (20130101)
A61K 31/437 (20130101)
A61K 31/4709 (20130101)
A61K 45/06 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)

Heterocyclic Compounds
C07D 333/38 (20130101)
C07D 409/12 (20130101)
C07D 471/04 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5088 (20130101)
G01N 2800/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045476 Bassler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Bonnie Bassler (Princeton, New Jersey);  Lee Swem (San Carlos, California)
ABSTRACT Methods are provided for identifying molecules that can be used to positively and negatively manipulate quorum-sensing-mediated communication to control bacterial behavior. Small-molecule antagonists that disrupt quorum-sensing-mediated activities are identified. Methods are provided for disrupting detection of acyl-homoserine lactone autoinducer in Gram-negative bacteria by contacting the bacteria with the antagonists. Methods of inhibiting quorum sensing-mediated activity in Gram-negative bacteria are provided wherein the activity is pathogenicity, bioluminescence, siderophore production, type III secretion, or metalloprotease production.
FILED Tuesday, September 17, 2013
APPL NO 14/028999
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 41/10 (20130101)
A01N 43/28 (20130101)
A01N 43/52 (20130101)
A01N 43/78 (20130101)
A01N 43/82 (20130101)
A01N 43/90 (20130101)
A01N 43/653 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)

Acyclic or Carbocyclic Compounds
C07C 317/24 (20130101)

Heterocyclic Compounds
C07D 235/28 (20130101)
C07D 249/12 (20130101)
C07D 277/42 (20130101)
C07D 285/14 (20130101)
C07D 327/04 (20130101)
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045483 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) City of Hope (Duarte, California);  Sanford-Burnham Medical Research Institute at Lake Nona (Orlanda, Florida)
ASSIGNEE(S) City of Hope (Duarte, California);  Sanford-Burnham Medical Research Institute (La Jolla, California)
INVENTOR(S) Yuan Chen (Arcadia, California);  Yi-Jia Li (Duarte, California);  Daniela Divlianska (Orlando, Florida);  Ekaterina Bobkova (Orlando, Florida);  Greg Roth (Orlando, Florida);  Jun Pu (Orlando, Florida);  Pasha Khan (Orlando, Florida)
ABSTRACT According to the embodiments described herein, a methods for inhibiting small ubiquitin-like modifier enzymes in a cell are provided. Such methods may include administering certain substituted pyrrolo[2,3-b]-quinoxalines to the cell. In some aspects, the small ubiquitin-like modifier enzyme is SUMO E1 or SUMO E2. In some aspects, the methods may be used to inhibit a cancer cell in vitro (e.g., grown in culture) or in vivo (e.g., as part of a tumor in a subject). In other embodiments, methods for treating a cancer, degenerative diseases and viral infection are provided. Such methods may include administering an effective amount of a pharmaceutical composition to a subject having cancer. The pharmaceutical composition may include a small ubiquitin-like modifier inhibitor compound. In some embodiments, the method for treating a disease may further comprise administering one or more DNA-damaging therapy in combination with administration of the pharmaceutical composition.
FILED Thursday, May 09, 2013
APPL NO 13/891076
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/555 (20130101)
A61K 31/555 (20130101)
A61K 33/24 (20130101)
A61K 33/24 (20130101)
A61K 41/00 (20130101)
A61K 41/00 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
C07D 493/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045484 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Paul B. Yu (Boston, Massachusetts);  Gregory D. Cuny (Houston, Texas);  Kenneth D. Bloch (Chestnut Hill, Massachusetts);  Randall T. Peterson (Belmont, Massachusetts);  Charles C. Hong (Nolensville, Tennessee)
ABSTRACT The present invention provides pyridinyl-substituted pyrazolyl pyrimidine small molecule inhibitors of bone morphogenetic protein (BMP) signaling having the structure of formula (I),
wherein variables A, B, E, F, X, Y, Z, Ar, L1, R4 and R15 are as defined in the specification. The compounds of the invention are useful in modulating cell growth, differentiation, proliferation, and apoptosis, and thus are useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.
FILED Friday, July 12, 2013
APPL NO 13/940641
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101)

Heterocyclic Compounds
C07D 487/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045512 Savage et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Scripps Research Institute (La Jolla, California);  Brigham Young University (Provo, Utah);  The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California);  Brigham Young University (Provo, Utah);  The University of Chicago (Chicago, Illinois)
INVENTOR(S) Paul B. Savage (Mapleton, Utah);  Albert Bendelac (Chicago, Illinois);  Luc Teyton (Delmar, California)
ABSTRACT This invention relates to galactosylceramide compounds.
FILED Monday, May 20, 2013
APPL NO 13/898070
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 5/04 (20130101) Original (OR) Class
C07H 7/06 (20130101)
C07H 13/04 (20130101)
C07H 15/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045526 Mosberg
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Henry I. Mosberg (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Henry I. Mosberg (Ann Arbor, Michigan)
ABSTRACT The invention provides a compound of formula (I), wherein R1 is H, C(NH)NH2, an amino acid, or a peptide; X is OH, NH2, NHR2, NR2R3, an amino acid, or a peptide; R2 and R3 are selected from alkyl, alkylenearyl, or alkyleneheteroaryl; each R4 and R5 is independently H or CH3; Z is 2-amino-2,3-dihydro-1H-indene-2-carboxylic acid; 2-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 6-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulene 6-carboxylic acid; cyclohexylalanine; cyclohexylglycine; homophenylalanine; 1-naphthylalanine; 2-naphthylalanine; 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; or octahydro-1H-indole-2-carboxylic acid; n is 0, 1, 2, 3, or 4; with the proviso that X is not NH2 when R1 is H, R4 is H, R5 is CH3, Z is Aci, and n is 2; or a pharmaceutically acceptable salt, ester or solvate thereof. A method of treating pain and a method for treating a mu-opioid receptor mediated disorder and/or a delta-opioid receptor mediated disorder also are provided.
FILED Friday, June 22, 2012
APPL NO 14/128800
ART UNIT 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/07 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 5/1016 (20130101) Original (OR) Class
C07K 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045527 Ball et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) WILLIAM MARSH RICE UNIVERSITY (Houston, Texas)
ASSIGNEE(S) WILLIAM MARSH RICE UNIVERSITY (Houston, Texas);  TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Zachary T. Ball (Houston, Texas);  Rituparna Kundu (Houston, Texas);  Brian V. Popp (Houston, Texas);  Dean R. Madden (Hanover, New Hampshire);  Patrick R. Cushing (Hanover, New Hampshire)
ABSTRACT Methods for targeting a protein by providing an inhibitor covalently linked to a rhodium(II) complex, introducing the inhibitor to the target protein and allowing the inhibitor and protein to interact. The rhodium(II) complex covalently linked to the inhibitor binds the target protein both inorganically and organically and forms stabilizing secondary contacts between the rhodium(II) complex and the protein.
FILED Wednesday, June 12, 2013
APPL NO 13/916359
ART UNIT 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48015 (20130101)

Peptides
C07K 1/107 (20130101)
C07K 1/1075 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045532 Broder et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Christopher C. Broder (Silver Spring, Maryland);  Katharine N. Bossart (San Francisco, California)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland)
INVENTOR(S) Christopher C. Broder (Silver Spring, Maryland);  Katharine N. Bossart (San Francisco, California)
ABSTRACT This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
FILED Friday, June 22, 2012
APPL NO 13/530922
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/07 (20130101)
C07K 14/115 (20130101) Original (OR) Class
C07K 16/1027 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/18222 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101)
G01N 33/56983 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045542 Oh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) SangKon Oh (Baltimore, Maryland);  Jacques F. Banchereau (Montclair, New Jersey);  Gerard Zurawski (Midlothian, Texas);  Hideki Ueno (Plano, Texas);  Ling Ni (Dallas, Texas)
ASSIGNEE(S) Baylor Research Institute (Dallas, Texas)
INVENTOR(S) SangKon Oh (Baltimore, Maryland);  Jacques F. Banchereau (Montclair, New Jersey);  Gerard Zurawski (Midlothian, Texas);  Hideki Ueno (Plano, Texas);  Ling Ni (Dallas, Texas)
ABSTRACT The present invention includes compositions and methods for enhancing Th1/Th17 cell responses and decreasing Th2 cell responses. In various embodiments the present invention describes activation of human dendritic cells and enhancement of antigen-specific T cell responses in a Dectin-1-expressing human dendritic cells comprising an anti-Dectin-1-specific antibody or fragment thereof fused with one or more antigens. TLR2 ligands may also be included to enhance the activation and for enhancement of T-cell responses. Further, the invention also includes methods based on the compositions described herein for the treatment of allergy, and asthma.
FILED Tuesday, August 28, 2012
APPL NO 13/596526
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/33 (20130101)
C07K 14/4741 (20130101)
C07K 16/2851 (20130101) Original (OR) Class
C07K 2319/42 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0639 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045552 Payne
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) R. Mark Payne (Clemons, North Carolina)
ASSIGNEE(S) Wake Forest University (Winston-Salem, North Carolina)
INVENTOR(S) R. Mark Payne (Clemons, North Carolina)
ABSTRACT A conjugate comprises: (a) a mitochondrial membrane-permeant peptide; (b) an active agent or compound of interest such as a detectable group or mitochondrial protein or peptide; and (c) a mitochondrial targeting sequence linking said mitochondrial membrane-permeant peptide and said active mitochondrial protein or peptide. The targeting sequence is one which is cleaved within the mitochondrial matrix, and not cleaved within the cellular cytoplasm, of a target cell into which said compound is delivered. Methods of use of such compounds are also described.
FILED Friday, April 08, 2011
APPL NO 13/082526
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 47/48246 (20130101)

Peptides
C07K 14/47 (20130101) Original (OR) Class
C07K 2319/07 (20130101)
C07K 2319/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045554 Olson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Timothy M. Olson (Rochester, Minnesota)
ABSTRACT This document relates to methods and materials for using nucleic acid and amino acid sequence variants of ribonucleic acid binding motif protein 20 (RBM20). For example, methods and materials for using nucleic acid sequence variants and/or their corresponding amino acid variants of RBM20 that are associated with dilated cardiomyopathy to identify mammals (e.g., humans) at risk of having dilated cardiomyopathy that is likely to progress to heart failure are provided.
FILED Thursday, September 19, 2013
APPL NO 14/032043
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)

Peptides
C07K 14/47 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/172 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045561 Kobilka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) THE BOARD OF TRUSTEE OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S) Brian Kobilka (Palo Alto, California);  Daniel Rosenbaum (Burlingame, California)
ABSTRACT Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising: a) a first portion of a G-protein coupled receptor (GPCR), where the first portion comprises the TM1, TM2, TM3, TM4 and TM5 regions of the GPCR; b) a stable, folded protein insertion; and c) a second portion of the GPCR, where the second portion comprises the TM6 and TM7 regions of the GPCR.
FILED Wednesday, December 18, 2013
APPL NO 14/133279
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/705 (20130101) Original (OR) Class
C07K 14/723 (20130101)
C07K 14/70571 (20130101)
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045579 Xia et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Yan Xia (Mountain View, California);  Benjamin R Sveinbjornsson (Pasadena, California);  Robert H Grubbs (South Pasadena, California);  Raymond Weitekamp (Pasadena, California);  Garret M Miyake (Pasadena, California);  Victoria Piunova (Altadena, California);  Christopher Scot Daeffler (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Yan Xia (Mountain View, California);  Benjamin R Sveinbjornsson (Pasadena, California);  Robert H Grubbs (South Pasadena, California);  Raymond Weitekamp (Pasadena, California);  Garret M Miyake (Pasadena, California);  Victoria Piunova (Altadena, California);  Christopher Scot Daeffler (Pasadena, California)
ABSTRACT The invention provides a class of wedge-type block copolymers having a plurality of chemically different blocks, at least a portion of which incorporates a wedge group-containing block providing useful properties. For example, use of one or more wedge group-containing blocks in some block copolymers of the invention significantly inhibits chain entanglement and, thus, the present block copolymers materials provide a class of polymer materials capable of efficient molecular self-assembly to generate a range of structures, such as periodic nanostructures and microstructures. Materials of the present invention include copolymers having one or more wedge group-containing blocks, and optionally for some applications copolymers also incorporating one or more polymer side group-containing blocks. The present invention also provides useful methods of making and using wedge-type block copolymers.
FILED Wednesday, March 13, 2013
APPL NO 13/801710
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 2201/0149 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/04 (20130101)
C08F 222/40 (20130101)
C08F 232/08 (20130101)
C08F 293/00 (20130101)
C08F 299/00 (20130101) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/08 (20130101)
C08G 81/00 (20130101)
C08G 2261/74 (20130101)
C08G 2261/126 (20130101)
C08G 2261/128 (20130101)
C08G 2261/146 (20130101)
C08G 2261/149 (20130101)
C08G 2261/418 (20130101)
C08G 2261/1426 (20130101)
C08G 2261/3324 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045657 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Science Foundation (NSF)
APPLICANT(S) Jennifer A. Lewis (Urbana, Illinois);  Robert F. Shepherd (St. Paul, Minnesota);  Robert A. Barry, III (Beaverton, Oregon);  Sara T. Parker (Portland, Oregon);  Jennifer N. H. Shepherd (St. Paul, Minnesota);  Pierre Wiltzius (Santa Barbara, California);  Ralph G. Nuzzo (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Jennifer A. Lewis (Urbana, Illinois);  Robert F. Shepherd (St. Paul, Minnesota);  Robert A. Barry, III (Beaverton, Oregon);  Sara T. Parker (Portland, Oregon);  Jennifer N. H. Shepherd (St. Paul, Minnesota);  Pierre Wiltzius (Santa Barbara, California);  Ralph G. Nuzzo (Champaign, Illinois)
ABSTRACT A viscoelastic ink for direct writing of hydrogel structures includes a long chain polymer and a photopolymerizable moiety, which may be a photopolymerizable monomer or a photopolymerizable group attached to the long chain polymer. The ink may also include a crosslinking agent, a photoinitiator, and water. The long chain polymer is present at a concentration greater than a critical overlap concentration c* of the long chain polymer in the ink.
FILED Tuesday, March 22, 2011
APPL NO 13/636542
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/16 (20130101)
A61L 27/16 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/52 (20130101)
A61L 27/56 (20130101)

Compositions of Macromolecular Compounds
C08L 5/08 (20130101)
C08L 33/10 (20130101)
C08L 33/10 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/10 (20130101)
C09D 11/16 (20130101) Original (OR) Class
C09D 11/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045727 Compans et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Richard L. Compans (Atlanta, Georgia);  Chinglai Yang (Decatur, Georgia);  Qizhi Yao (Houston, Texas);  Sang-moo Kang (Norcross, Georgia)
ASSIGNEE(S) EMORY UNIVERSITY (Atlanta, Georgia)
INVENTOR(S) Richard L. Compans (Atlanta, Georgia);  Chinglai Yang (Decatur, Georgia);  Qizhi Yao (Houston, Texas);  Sang-moo Kang (Norcross, Georgia)
ABSTRACT Briefly described, virus-like particles, methods of preparing virus-like particles, immunogenic compositions that include virus-like particles, and methods of eliciting an immune response using immunogenic compositions that include virus-like particles are described herein. A virus-like particle (VLP) can include a viral core protein that can self assemble into the VLP core and at least one viral surface envelope glycoprotein expressed on the surface of the VLP. The VLP can also optionally include at least one adjuvant molecule expressed on the surface of the VLP.
FILED Tuesday, April 04, 2006
APPL NO 11/397830
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/21 (20130101)
A61K 2039/5258 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101) Original (OR) Class
C12N 2740/15022 (20130101)
C12N 2740/16023 (20130101)
C12N 2740/16222 (20130101)
C12N 2760/12022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045731 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Ronald Li (Davis, California);  Chung-wah Siu (Davis, California);  Deborah K. Lieu (Davis, California);  Jing Liu (Davis, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ronald Li (Davis, California);  Chung-wah Siu (Davis, California);  Deborah K. Lieu (Davis, California);  Jing Liu (Davis, California)
ABSTRACT This invention provides an isolated stem cell that has been modified to provide, enhance or contain the functional characteristics of the sarcoplasmic reticulum (SR). The isolated stem cells are modified in one or more of the following manners: by expressing a calcium channel protein; by expressing a calcium pump protein such as the sarcro/endoplasmic reticulum Ca2+-ATPase (SERCA) protein; by inhibiting or downregulating expression of the Na+/Ca+ exchanger (NCX) protein; by expressing a calcium handling protein; by expressing a transverse (t-tubule; and/or by expressing a transverse (t-tubule biogenic protein. After the cell has been modified, it may be expanded to a substantially homogenous population of these cells or alternatively, differentiated to a more mature cell type. Compositions containing these cells and population of cells are also provided by this invention. The cells and compositions can he used to regenerate cardiac tissue, improve cardiac function, restore action potential of cardiac tissue; and treat or prevent cardiac malfunction. These methods can be achieved by administering an effective amount of a cell or population of cells or tissue of this invention to a host in need thereof. The cells and population of cells can be used diagnostically to screen drug or other therapeutic candidates.
FILED Thursday, September 11, 2008
APPL NO 12/677790
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0606 (20130101) Original (OR) Class
C12N 5/0657 (20130101)
C12N 2500/25 (20130101)
C12N 2500/33 (20130101)
C12N 2500/44 (20130101)
C12N 2501/115 (20130101)
C12N 2502/13 (20130101)
C12N 2503/02 (20130101)
C12N 2506/02 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045735 Muschler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) George Muschler (Cleveland Heights, Ohio);  Tonya Caralla (Lakewood, Ohio);  Vincent Hascall (Cleveland Heights, Ohio);  Ronald Midura (Shaker Heights, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
INVENTOR(S) George Muschler (Cleveland Heights, Ohio);  Tonya Caralla (Lakewood, Ohio);  Vincent Hascall (Cleveland Heights, Ohio);  Ronald Midura (Shaker Heights, Ohio)
ABSTRACT Methods for enriching, detecting, or using adult stem cells through the use of recognition ligands that specifically bind to ECM components retained to the surfaces of adult stem cells are described. An ECM component such as hyaluronan that is retained to the surfaces of adult stem cells when removed from animal tissues can be used to detect a diverse population of adult stem cells based on the nature of the ECM niche region in which the adult stem cells normally reside. For example, a separation method such as magnetic separation can be used to detect and isolate or enrich adult stem cells based on a recognition ligand that is specific for an ECM component that is retained to the surfaces of adult stem cells to a greater degree than to other cells in the population.
FILED Thursday, April 03, 2008
APPL NO 12/594493
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0663 (20130101) Original (OR) Class
C12N 2500/38 (20130101)
C12N 2501/39 (20130101)
C12N 2501/905 (20130101)
C12N 2533/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045740 Martin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Craig T. Martin (Amherst, Massachusetts);  Luis Ramirez-Tapia (Sunderland, Massachusetts)
ABSTRACT The invention relates to modified T7-related RNA polymerases and methods of use thereof. In some embodiments, the invention relates to modified T7-related RNA polymerases that transcribe RNA with reduced abortive cycling and increased efficiency compared with native T7-related RNA polymerases.
FILED Monday, February 25, 2013
APPL NO 13/775929
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/127 (20130101) Original (OR) Class
C12N 9/1247 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
C12P 21/02 (20130101)

Enzymes
C12Y 207/07006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045749 Naar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Anders M. Naar (Arlington, Massachusetts);  Seyed Hani Najafi-Shoushtari (Brighton, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Anders M. Naar (Arlington, Massachusetts);  Seyed Hani Najafi-Shoushtari (Brighton, Massachusetts)
ABSTRACT Methods for targeting microRNA 128 (miR-128) for regulating cholesterol/lipid metabolism and insulin sensitivity.
FILED Friday, January 13, 2012
APPL NO 13/979428
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 31/7105 (20130101)
A61K 38/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101) Original (OR) Class
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/113 (20130101)
C12N 2310/141 (20130101)
C12N 2310/3231 (20130101)
C12N 2330/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045751 Place et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Robert F. Place (San Francisco, California);  Long-Cheng Li (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Robert F. Place (San Francisco, California);  Long-Cheng Li (San Francisco, California)
ABSTRACT Methods, compositions and kits are provided for increasing the expression of a gene product in a cell by contacting the cell with a modified small activating RNA (saRNA) molecule, which provides for an increase in gene expression that is improved over the increase in expression provided by traditional saRNAs. These methods and compositions find use in any application in which an increase in gene expression in a cell is desired.
FILED Thursday, April 28, 2011
APPL NO 13/096817
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2320/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045752 Li
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Long-Cheng Li (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Long-Cheng Li (San Francisco, California)
ABSTRACT The present disclosure provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a NKX3-1 gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a promoter region sequence of the NKX3-1 gene. The present disclosure also provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a KLF4 gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a promoter region sequence of the KLF4 gene.
FILED Tuesday, March 08, 2011
APPL NO 13/583905
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045756 Scheinberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) David A. Scheinberg (New York, New York);  Prabodhika Mallikaratchy (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) David A. Scheinberg (New York, New York);  Prabodhika Mallikaratchy (New York, New York)
ABSTRACT Aptamers and improved aptamers are provided with enhanced efficacy for binding to target molecules in vivo or for treating cancer or other diseases. Such improvements in aptamers are provided that enhance in vivo efficacy such as binding to the target molecule or enhancing anti-cancer activity. Such improvements also include stability to serum nucleases, reduced binding to a soluble form of the target molecule, increased avidity, affinity or specificity to the target molecule on a cell surface, increased lifetime in circulation, or any combination of the foregoing. Improvements are provided by truncation, multimerization, including at least one non-natural nucleic acid, adding a 3′ or 5′ polyethylene glycol, or any combination thereof. Aptamers for treatment of autoimmune diseases are also provided.
FILED Tuesday, November 16, 2010
APPL NO 13/510221
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/115 (20130101) Original (OR) Class
C12N 2310/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045759 Williams
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) James Arthur Williams (Lincoln, Nebraska)
ASSIGNEE(S)
INVENTOR(S) James Arthur Williams (Lincoln, Nebraska)
ABSTRACT The present invention relates to the production of covalently closed circular (ccc) recombinant DNA molecules such as plasmids, cosmids, bacterial artificial chromosomes (BACs), bacteriophages, viral vectors and hybrids thereof, and more particularly to vector modifications that improve production yield of said DNA molecules in fermentation culture.
FILED Tuesday, January 19, 2010
APPL NO 12/656115
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/69 (20130101) Original (OR) Class
C12N 15/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045777 Choi et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) Korea Center for Disease Control and Prevention (Cheongwon-gun, Chungcheonbuk-, South Korea);  Chungbuk National University Industry-Academic Cooperation Foundation (Cheongju, Chungcheongbuk-Do, South Korea)
ASSIGNEE(S) Korea Center for Disease Control and Prevention (Cheongwon-gun, Chungcheongbuk-do, South Korea);  Chungbuk National University Industry-Academic Cooperation Foundation (Cheongju, Chungcheongbuk-do, South Korea)
INVENTOR(S) Young Ki Choi (Chungcheongbuk-Do, South Korea);  Chun Kang (Chungcheongnam-Do, South Korea);  Kee Jong Hong (Seoul, South Korea);  Min Suk Song (Chungcheongbuk-Do, South Korea);  Yun Hee Baek (Chungcheongbuk-Do, South Korea)
ABSTRACT The present invention relates to a pol I promoter derived from Vero cells and a recombinant vector containing the same. When the pol I promoter derived from Vero cells according to the present invention is utilized, viruses can be manufactured efficiently, and consequently, the manufacture of both seasonal influenza vaccine and pandemic vaccine can be prepared more quickly to usefully address either situation.
FILED Tuesday, September 17, 2013
APPL NO 14/029465
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/1252 (20130101)
C12N 15/85 (20130101) Original (OR) Class
C12N 2760/16051 (20130101)
C12N 2760/16052 (20130101)
C12N 2760/16151 (20130101)
C12N 2760/16152 (20130101)
C12N 2830/85 (20130101)

Enzymes
C12Y 207/07007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045798 Williams et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) John G. K. Williams (Lincoln, Nebraska);  Jon P. Anderson (Lincoln, Nebraska)
ASSIGNEE(S) PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (Menlo Park, California)
INVENTOR(S) John G. K. Williams (Lincoln, Nebraska);  Jon P. Anderson (Lincoln, Nebraska)
ABSTRACT The present invention provides novel compositions, methods and apparatus for DNA sequencing that can be performed, e.g., in a two-electrode chamber. The present invention also provides a method for sequencing a nucleic acid comprising immobilizing a plurality of complexes comprising a target nucleic acid, a primer nucleic acid, and a polymerase onto a surface, contacting the surface with a plurality of charged particles comprising a nucleotide phosphate by applying an electric field, reversing the electric field to transport unbound charged particles away from the surface, and detecting the incorporation of a nucleotide phosphate into a single molecule of the primer nucleic acid.
FILED Wednesday, March 15, 2006
APPL NO 11/377136
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 2525/113 (20130101)
C12Q 2525/117 (20130101)
C12Q 2563/107 (20130101)
C12Q 2563/149 (20130101)
C12Q 2565/518 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046085 Schoess et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Jeffrey N. Schoess (Howard Lake, Minnesota);  Kannan Sivaprakasam (St. Cloud, Minnesota)
ASSIGNEE(S) Eden Medical, Inc. (Howard Lake, Minnesota)
INVENTOR(S) Jeffrey N. Schoess (Howard Lake, Minnesota);  Kannan Sivaprakasam (St. Cloud, Minnesota)
ABSTRACT Miniature pumps for dispensing a volume a flowable substance are described. One pump embodiment includes an environmentally-responsive plug layer that can contract in size, e.g., when exposed to an environmental change such as temperature, to allow an activation solution to flow to a layer of expandable material, such as a superporous hydrogel. Expansion of the expandable material urges a diaphragm into a chamber that holds the dispensable fluid, gas, or gel, forcing the fluid, gas or gel out of the pump.
FILED Friday, August 31, 2012
APPL NO 13/601809
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Positive-displacement Machines for Liquids; Pumps
F04B 19/006 (20130101) Original (OR) Class
F04B 19/24 (20130101)
F04B 43/10 (20130101)
F04B 43/043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046514 Sista et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Ramakrishna Sista (Morrisville, North Carolina);  Vamsee K. Pamula (Durham, North Carolina);  Michael G. Pollack (Durham, North Carolina);  Vijay Srinivasan (Durham, North Carolina);  Allen E. Eckhardt (Durham, North Carolina);  Richard B. Fair (Durham, North Carolina)
ASSIGNEE(S) ADVANCED LIQUID LOGIC, INC. (San Diego, California);  DUKE UNIVERSITY (Durham, North Carolina)
INVENTOR(S) Ramakrishna Sista (Morrisville, North Carolina);  Vamsee K. Pamula (Durham, North Carolina);  Michael G. Pollack (Durham, North Carolina);  Vijay Srinivasan (Durham, North Carolina);  Allen E. Eckhardt (Durham, North Carolina);  Richard B. Fair (Durham, North Carolina)
ABSTRACT A method of providing a droplet in contact with a magnetically responsive bead and having a reduced quantity of a substance. The method generally includes the steps of (a) providing a droplet actuator (200) comprising: (i) a substrate (210) comprising electrodes (214) arranged for conducting droplet operations on a surface; (ii) a starting droplet (218/222) comprising: (1) one or more magnetically responsive beads (220); (2) a starting quantity of the substance; and (3) a starting volume; (b) magnetically immobilizing the one or more magnetically responsive beads at a location which is at a distance from a target droplet splitting zone, (224); (c) conducting one or more droplet operations comprising droplet dividing operations selected to divide the combined droplet to yield a set of droplets comprising: (i) a droplet (218) comprising substantially all of the one or more magnetically responsive beads and having a decreased quantity of the substance relative to the starting concentration; and (ii) a droplet (222) substantially lacking the magnetically responsive beads.
FILED Monday, February 11, 2008
APPL NO 12/524495
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 3/502784 (20130101)
B01L 2200/025 (20130101)
B01L 2200/028 (20130101)
B01L 2200/141 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/043 (20130101)
B01L 2400/0427 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 25/01 (20130101)
C12M 25/16 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54326 (20130101) Original (OR) Class
G01N 33/54386 (20130101)
G01N 35/0098 (20130101)
G01N 2035/1046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046520 Semenova et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) Vera A. Semenova (Lilburn, Georgia);  Conrad P. Quinn (Lilburn, Georgia);  Jan Pohl (Tucker, Georgia);  Pavel Svoboda (Atlanta, Georgia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia)
INVENTOR(S) Vera A. Semenova (Lilburn, Georgia);  Conrad P. Quinn (Lilburn, Georgia);  Jan Pohl (Tucker, Georgia);  Pavel Svoboda (Atlanta, Georgia)
ABSTRACT Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus anthracis infection. The recognition of these epitopes correlates with autoimmunity in a subject. Also provided are vaccines that include at least one of these epitopes that when administered to a subject provide improved acquired immunity.
FILED Thursday, February 10, 2011
APPL NO 13/577878
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/07 (20130101)

Peptides
C07K 14/32 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56911 (20130101) Original (OR) Class
G01N 2333/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046525 Walton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Troy Walton (Pasadena, California);  Chris Gandhi (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Troy Walton (Pasadena, California);  Chris Gandhi (Pasadena, California)
ABSTRACT A method of counting protein subunits to determine the oligomeric state of an oligomeric protein complex includes tagging and expressing the protein subunits with a mass/charge tag and selectively removing each mass/charge tag. The number of protein subunits of the oligomeric complex corresponds to the number of mass/charge tags removed.
FILED Monday, August 01, 2011
APPL NO 13/195788
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6803 (20130101) Original (OR) Class
G01N 33/6842 (20130101)
G01N 2333/95 (20130101)
G01N 2550/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046529 Fong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Lawrence H. Fong (Palo Alto, California);  Yafei Hou (Mountain View, California);  Jason J. Devoss (San Francisco, California);  Mark Stuart Anderson (Larkspur, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Lawrence H. Fong (Palo Alto, California);  Yafei Hou (Mountain View, California);  Jason J. Devoss (San Francisco, California);  Mark Stuart Anderson (Larkspur, California)
ABSTRACT The present disclosure provides prostatitis-associated antigens, and compositions comprising the antigens. The present disclosure provides diagnostic methods, generally involving assaying the level of an immune response specific for a prostatitis-associated antigen in an individual. Kits suitable for use in performing such diagnostic assays are also provided. The present disclosure further provides methods of treating prostatitis, methods of treating prostate cancer, and methods of treating benign prostatic hyperplasia.
FILED Tuesday, March 30, 2010
APPL NO 13/262752
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)

Peptides
C07K 14/47 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101) Original (OR) Class
G01N 2800/342 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046530 Zhong
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Guangming Zhong (San Antonio, Texas)
ABSTRACT The present invention provides Chlamydia proteins and fragments thereof and methods of use in diagnostic assays.
FILED Friday, November 30, 2012
APPL NO 13/691260
ART UNIT 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101) Original (OR) Class
G01N 33/56927 (20130101)
G01N 2800/52 (20130101)
G01N 2800/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046535 Montgomery
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Robert Montgomery (Cedarburg, Wisconsin)
ASSIGNEE(S) BLOODCENTER RESEARCH FOUNDATION (Milwaukee, Wisconsin)
INVENTOR(S) Robert Montgomery (Cedarburg, Wisconsin)
ABSTRACT Methods and kits for measuring levels of von Willebrand factor function in a sample without using a platelet aggregation agonist, such as ristocetin, comprising recombinant glycoprotein Ibα having at least two of a G233V, D235Y and M239V mutations and an agent to detect a complex between the recombinant glycoprotein Ibα and von Willebrand factor.
FILED Thursday, March 15, 2012
APPL NO 13/421217
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/745 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/86 (20130101) Original (OR) Class
G01N 33/5008 (20130101)
G01N 2333/705 (20130101)
G01N 2333/755 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047659 Klose
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Alexander Klose (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Alexander Klose (New York, New York)
ABSTRACT The present disclosure can provide apparatus, system, methods, and computer-accessible medium for generating particular information which is at least one of three-dimensional information or intensity information of a tissue portion which can include at least one of a tissue surface or a tissue volume. For example, the exemplary method can include determining a light intensity distribution of light provided on the tissue portion, using the light intensity distribution, determining one or more attenuation maps of the tissue portion, obtaining one or more multispectral measurements of the light intensity distribution on the tissue portion taken from one or more views, and generating the particular information using an image reconstruction procedure in conjunction with data from the one or more tissue attenuation maps and the multispectral measurements.
FILED Thursday, April 28, 2011
APPL NO 13/695227
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101)
A61B 5/055 (20130101)
A61B 5/0073 (20130101)
A61B 5/0261 (20130101)
A61B 5/14551 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047660 Khurd et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Parmeshwar Khurd (Princeton, New Jersey);  Ali Kamen (Skillman, New Jersey);  Hari Sundar (Austin, Texas);  John V. Frangioni (Wayland, Massachusetts);  Summer Gibbs-Strauss (Cambridge, Massachusetts)
ASSIGNEE(S) Siemens Corporation (Iselin, New Jersey);  Beth Israel Deaconess Medical Center (Boston, Massachusetts)
INVENTOR(S) Parmeshwar Khurd (Princeton, New Jersey);  Ali Kamen (Skillman, New Jersey);  Hari Sundar (Austin, Texas);  John V. Frangioni (Wayland, Massachusetts);  Summer Gibbs-Strauss (Cambridge, Massachusetts)
ABSTRACT Methods for analyzing biomedical data include: (a) obtaining macroscopic imaging data; (b) obtaining histopathological imaging data; (c) executing a parallel algorithm stored on a non-transient computer-readable medium to compute one or a plurality of network cycle features of a relative neighborhood graph derived from the histopathological imaging data; (d) registering the macroscopic imaging data and the histopathological imaging data; and (e) correlating the macroscopic imaging data and the network cycle features. Systems for analyzing biomedical data and computer readable storage media are described.
FILED Thursday, February 28, 2013
APPL NO 13/780370
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/5229 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/0032 (20130101)
G06T 17/20 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/20072 (20130101)
G06T 2207/30024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047662 Diem et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Max Diem (Boston, Massachusetts);  Milos Miljkovic (Jamaica Plain, Massachusetts);  Melissa Romeo (Jamaica Plain, Massachusetts);  Benjamin Bird (Roslindale, Massachusetts);  Jennifer Schubert (Boston, Massachusetts);  Kostas Papamarkakis (Springfield, Massachusetts)
ABSTRACT Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell.
FILED Wednesday, March 20, 2013
APPL NO 13/847591
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/402 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/30024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048079 Krutchinsky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Rockefeller University (New York, New York)
ASSIGNEE(S) THE ROCKEFELLER UNIVERSITY (New York, New York)
INVENTOR(S) Andrew N. Krutchinsky (New York, New York);  Julio Padovan (New York, New York);  Herbert Cohen (New York, New York);  Brian T. Chait (New York, New York)
ABSTRACT An ion transfer device for transferring ions emerging from an electrospray ion source at atmosphere to a vacuum chamber includes an inner surface in the shape of a diverging conical duct. The ion transfer device has an entrance aperture for positioning proximate the exit port of the electrospray ion source emitter, the entrance aperture receiving the electrosprayed ions from the exit port of the electrospray ion source emitter at atmosphere, the diverging conical duct being an electrode toward which the ions migrate and having an exit aperture with an inner diameter larger than an inner diameter of its entrance aperture, the exit aperture enclosed in the vacuum chamber, the diverging conical duct transporting the ions from atmosphere to vacuum. The vacuum chamber can be a chamber of a vacuum housing enclosing a mass analyzer.
FILED Thursday, March 14, 2013
APPL NO 13/827727
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/062 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 09044347 Cederna et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Paul S. Cederna (Milan, Michigan);  Brent M. Egeland (Ann Arbor, Michigan);  Mohammad Reza Abidian (State College, Pennsylvania);  Antonio Peramo (Ann Arbor, Michigan);  Melanie G. Urbanchek (Ann Arbor, Michigan);  Daryl R. Kipke (Pinckney, Michigan);  Sarah Richardson-Burns (Ann Arbor, Michigan);  David C. Martin (Lincoln University, Pennsylvania);  Eugene D. Daneshvar (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Paul S. Cederna (Milan, Michigan);  Brent M. Egeland (Ann Arbor, Michigan);  Mohammad Reza Abidian (State College, Pennsylvania);  Antonio Peramo (Ann Arbor, Michigan);  Melanie G. Urbanchek (Ann Arbor, Michigan);  Daryl R. Kipke (Pinckney, Michigan);  Sarah Richardson-Burns (Ann Arbor, Michigan);  David C. Martin (Lincoln University, Pennsylvania);  Eugene D. Daneshvar (Ann Arbor, Michigan)
ABSTRACT A hybrid bioelectrical interface (HBI) device can be an implantable device comprising an abiotic component operable to transmit charge via electrons or ions; a biological component interfacing with the neural tissue, the biological component being sourced from biologic, biologically-derived, or bio-functionalized material; and a conjugated polymer component that together provide a way to chronically interface living neural tissue with electronic devices for extended durations (e.g. greater than 10 years). In some embodiments, conjugated polymers provide a functional electrical interface for charge transfer and signal transduction between the nervous system and an electronic device (e.g. robotic prosthetic limb, retinal implant, microchip).
FILED Wednesday, August 15, 2012
APPL NO 13/586350
ART UNIT 3766 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101) Original (OR) Class
A61F 2250/0001 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/34 (20130101)
A61L 27/3675 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/05 (20130101)
A61N 1/0543 (20130101)
A61N 1/0551 (20130101)
A61N 1/36125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044601 Currell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Fred Currell (Belfast, United Kingdom);  Marcus Mendenhall (Nashville, Tennessee)
ASSIGNEE(S) Dr. Fred J. Currell (Belfast, Ireland);  Marcus Mendenhall (Nashville, Tennessee)
INVENTOR(S) Fred Currell (Belfast, United Kingdom);  Marcus Mendenhall (Nashville, Tennessee)
ABSTRACT A method for estimating a radiation dose and distribution for a target volume is provided. The method includes receiving a simulated dose array (606) describing a plurality of simulated dose values for a plurality of voxels in the target volume, generating an energy deposition coefficient function for the plurality of voxels (608), and obtaining a raw fluence array based at least on the simulated dose array and the energy deposition coefficient function (612). The method also includes generating an adjusted fluence array (613) based on the raw fluence array and at least one adjustment criteria, and generating an adjusted dose array (622) for the target volume based on the adjusted fluence array and the energy deposition coefficient function.
FILED Monday, October 19, 2009
APPL NO 13/125132
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/03 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1031 (20130101) Original (OR) Class
A61N 2005/1034 (20130101)

Electric Digital Data Processing
G06F 17/5009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045211 Geder et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America Represented by the Secretary of the Navy Chief of Naval Research ONR/NRL (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jason D. Geder (Arlington, Virginia);  John S. Palmisano (Silver Spring, Maryland);  Marius D. Pruessner (Silver Spring, Maryland);  Ravi Ramamurti (Silver Spring, Maryland)
ABSTRACT A robotic mechanical fin, having a motor housing containing a plurality of rib rotation motors, rib spars, and a plurality of ribs, mechanically movable and communicatively coupled to the plurality of rib rotation motors and shafts, where the plurality of ribs are rotationally coupled to and actuated by the plurality of rib rotation motors and shafts. The mechanical fin further includes a flexible fin casing, within which the ribs reside, forming the complete actively controlled curvature robotic propulsion and steering apparatus. The mechanical fin, is connected to a plurality of control electronics circuits and a computer processor programmed with actuation code that when executed by the computer processor causes automated actuation of simultaneous propulsion and steering maneuverability of the actively controlled curvature, robotic, mechanical fin.
FILED Tuesday, September 17, 2013
APPL NO 13/987921
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Marine Propulsion or Steering
B63H 1/38 (20130101) Original (OR) Class
B63H 5/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045343 Raney et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Jordan R. Raney (Pasadena, California);  Chiara Daraio (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Jordan R. Raney (Pasadena, California);  Chiara Daraio (Pasadena, California)
ABSTRACT Syntheses of carbon nanotubes (CNT) are disclosed. The syntheses can take place on a thermally oxidized silicon surface placed inside a furnace prior to a reaction. The setup can have many variables that could affect the resulting CNT arrays, including flow rate and composition of carrier gas, flow rate and composition of precursor solution, and temperature. By varying such variables the density of the resulting CNT arrays can be controlled.
FILED Thursday, June 07, 2012
APPL NO 13/491014
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 31/0226 (20130101) Original (OR) Class
C01B 31/0273 (20130101)
C01B 31/0438 (20130101)
C01B 2202/08 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24983 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045347 Pope et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Edward J. A. Pope (Oak Park, California);  Christopher L. Hill (Woodland Hills, California);  Carl N. Brabham (Thousand Oaks, California);  Jerry M. King (Granada Hills, California);  Bernard T. Morkunas (Thousand Oaks, California)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Edward J. A. Pope (Oak Park, California);  Christopher L. Hill (Woodland Hills, California);  Carl N. Brabham (Thousand Oaks, California);  Jerry M. King (Granada Hills, California);  Bernard T. Morkunas (Thousand Oaks, California)
ABSTRACT A novel polycrystalline stoichiometric fine SiC fiber substantially free of impurities is produced using a novel pre-ceramic polymer. The pre-ceramic polymer is prepared by reacting a mixture of chlorodisilane, boron trichloride, and a vinyl chlorodisilane with an excess of hexamethyldisilazane to form the pre-ceramic polymer resin, which may then be melt-spun, cured, pyrolyzed and heat-treated to obtain the finished SiC fiber. The manufacturing process for the production of the fine SiC ceramic fiber allows for flexibility with respect to cross-linking, in that low-cost thermal treatments may replace more complex methods, while obtaining fibers with improved materials properties as compared to currently available SiC fibers.
FILED Monday, February 28, 2011
APPL NO 13/037151
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 21/068 (20130101)
C01B 21/0643 (20130101)
C01B 31/36 (20130101) Original (OR) Class
C01B 35/146 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/6229 (20130101)
C04B 35/6267 (20130101)
C04B 35/6268 (20130101)
C04B 35/6269 (20130101)
C04B 35/62281 (20130101)
C04B 35/62295 (20130101)
C04B 2235/72 (20130101)
C04B 2235/96 (20130101)
C04B 2235/483 (20130101)
C04B 2235/722 (20130101)
C04B 2235/723 (20130101)
C04B 2235/5252 (20130101)
C04B 2235/5264 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 77/54 (20130101)
C08G 77/62 (20130101)
C08G 79/08 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 9/10 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2918 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045374 Keller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Teddy M. Keller (Fairfax Station, Virginia);  Andrew Saab (Washington, District of Columbia);  Matthew Laskoski (Springfield, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Teddy M. Keller (Fairfax Station, Virginia);  Andrew Saab (Washington, District of Columbia);  Matthew Laskoski (Springfield, Virginia)
ABSTRACT A composition having nanoparticles of silicon carbide and a carbonaceous matrix or silicon matrix. The composition is not in the form of a powder. A composition having silicon and an organic compound having a char yield of at least 60% by weight or a thermoset made from the organic compound. A method of combining silicon and the organic compound and heating to form silicon carbide or silicon nitride nanoparticles.
FILED Monday, May 19, 2014
APPL NO 14/281008
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 31/36 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/52 (20130101)
C04B 35/76 (20130101)
C04B 35/83 (20130101)
C04B 35/522 (20130101)
C04B 35/524 (20130101)
C04B 35/573 (20130101) Original (OR) Class
C04B 35/591 (20130101)
C04B 35/806 (20130101)
C04B 2235/48 (20130101)
C04B 2235/77 (20130101)
C04B 2235/80 (20130101)
C04B 2235/95 (20130101)
C04B 2235/383 (20130101)
C04B 2235/421 (20130101)
C04B 2235/422 (20130101)
C04B 2235/428 (20130101)
C04B 2235/526 (20130101)
C04B 2235/762 (20130101)
C04B 2235/767 (20130101)
C04B 2235/781 (20130101)
C04B 2235/3834 (20130101)
C04B 2235/3873 (20130101)
C04B 2235/5216 (20130101)
C04B 2235/5248 (20130101)
C04B 2235/5288 (20130101)
C04B 2235/5436 (20130101)
C04B 2235/6562 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045387 Yaghi et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Energy (DOE)
APPLICANT(S) Omar M. Yaghi (Los Angeles, California);  Alexander U. Czaja (Dirmstein, Germany);  Bo Wang (Beijing, China PRC);  Zheng Lu (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  BASF SE (Ludwigshafen, Germany)
INVENTOR(S) Omar M. Yaghi (Los Angeles, California);  Alexander U. Czaja (Dirmstein, Germany);  Bo Wang (Beijing, China PRC);  Zheng Lu (Los Angeles, California)
ABSTRACT The disclosure provides methods for the use of open metal frameworks to catalyze coupling reactions.
FILED Tuesday, July 27, 2010
APPL NO 13/387598
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 1/321 (20130101)
C07C 1/321 (20130101)
C07C 15/14 (20130101)
C07C 17/263 (20130101)
C07C 17/263 (20130101)
C07C 25/18 (20130101)
C07C 201/12 (20130101) Original (OR) Class
C07C 201/12 (20130101)
C07C 205/06 (20130101)
C07C 209/68 (20130101)
C07C 209/68 (20130101)
C07C 211/50 (20130101)
C07C 253/30 (20130101)
C07C 253/30 (20130101)
C07C 255/51 (20130101)
C07C 2523/72 (20130101)
C07C 2531/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045470 Wu et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Tom Yao Hsiang Wu (San Diego, California);  Yongkai Li (San Diego, California);  Alex Cortez (San Diego, California);  Kathy Yue (Riverside, California);  Xiaoyue Zhang (San Diego, California);  Manmohan Singh (Lexington, Massachusetts);  David Skibinski (Siena, Italy)
ASSIGNEE(S) IRM LLC (Hamilton, Bermuda)
INVENTOR(S) Tom Yao Hsiang Wu (San Diego, California);  Yongkai Li (San Diego, California);  Alex Cortez (San Diego, California);  Kathy Yue (Riverside, California);  Xiaoyue Zhang (San Diego, California);  Manmohan Singh (Lexington, Massachusetts);  David Skibinski (Siena, Italy)
ABSTRACT The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.
FILED Wednesday, September 01, 2010
APPL NO 12/874153
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045532 Broder et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Christopher C. Broder (Silver Spring, Maryland);  Katharine N. Bossart (San Francisco, California)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Rockville, Maryland)
INVENTOR(S) Christopher C. Broder (Silver Spring, Maryland);  Katharine N. Bossart (San Francisco, California)
ABSTRACT This invention relates to soluble forms of G glycoprotein from Hendra and Nipah virus. In particular, this invention relates to compositions comprising soluble forms of G glycoprotein from Hendra and Nipah virus and also to diagnostic and therapeutic methods using the soluble forms of G glycoprotein from Hendra and Nipah virus. Further, the invention relates to therapeutic antibodies including neutralizing antibodies, and vaccines for the prevention and treatment of infection by Hendra and Nipah viruses.
FILED Friday, June 22, 2012
APPL NO 13/530922
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 14/005 (20130101)
C07K 14/07 (20130101)
C07K 14/115 (20130101) Original (OR) Class
C07K 16/1027 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/18222 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6854 (20130101)
G01N 33/56983 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045576 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Shaoyi Jiang (Redmond, Washington);  Shengfu Chen (Zhejiang, China PRC)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Shaoyi Jiang (Redmond, Washington);  Shengfu Chen (Zhejiang, China PRC)
ABSTRACT Nonfouling copolymers and hydrogels comprising positively charged repeating units or latent positively charged repeating units and negatively charged units or latent positively charged units.
FILED Monday, February 09, 2009
APPL NO 12/367744
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/20 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/26 (20130101) Original (OR) Class
C08F 220/34 (20130101)
C08F 222/1006 (20130101)

Compositions of Macromolecular Compounds
C08L 51/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045623 Matter et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Paul H. Matter (Columbus, Ohio);  Christopher T. Holt (Bexley, Ohio);  Michael G. Beachy (Gahanna, Ohio)
ASSIGNEE(S) PH MATTER, LLC (Columbus, Ohio)
INVENTOR(S) Paul H. Matter (Columbus, Ohio);  Christopher T. Holt (Bexley, Ohio);  Michael G. Beachy (Gahanna, Ohio)
ABSTRACT A method of forming boron nitride nanoparticles. A plurality of precursor molecules comprising boron, nitrogen and hydrogen may be decomposed in a first heating zone to form a plurality of gaseous molecules that contain bonded boron and nitrogen, followed by heating to a second, higher temperature thereby causing the gaseous molecules to react and nucleate to form a plurality of boron nitride nanoparticles. Depending on processing temperatures, the boron nitride nanoparticles may include amorphous forms, crystalline forms, or combinations thereof. Precursor molecules may include ammonia borane, borazine, cycloborazanes, polyaminoborane, polyiminoborane, and mixtures thereof. The boron nitride nanoparticles may be incorporated into a variety of dispersions, composites, and coatings; and in one embodiment, may be a component of a propellant, wherein the boron nitride nanoparticles may confer a range of advantages to gun barrels in which such propellants may be fired.
FILED Wednesday, October 10, 2012
APPL NO 13/648660
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 21/0646 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/76 (20130101)
C01P 2002/85 (20130101)
C01P 2004/03 (20130101)
C01P 2004/62 (20130101)
C01P 2004/64 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/38 (20130101) Original (OR) Class
C08K 3/38 (20130101)
C08K 3/38 (20130101)
C08K 7/18 (20130101)

Compositions of Macromolecular Compounds
C08L 1/18 (20130101)
C08L 1/18 (20130101)
C08L 1/18 (20130101)
C08L 1/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045651 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Jiun-Jeng Chen (Gainesville, Florida);  Anthony B. Brennan (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Jiun-Jeng Chen (Gainesville, Florida);  Anthony B. Brennan (Gainesville, Florida)
ABSTRACT Disclosed herein is an article comprising a substrate; a polymer disposed upon the substrate; the polymer having a number average molecular weight of about 2,000 to about 5,000 grams per mole; where each polymer is separated from a neighboring polymer by an average distance of 2.5 Angstroms to 5,000 Angstroms. Disclosed herein is a method comprising disposing upon a substrate a polymer; the polymer having a number average molecular weight of 2,000 to about 5,000 grams per mole.
FILED Monday, June 20, 2011
APPL NO 13/164600
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 59/04 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/06 (20130101)
C08F 220/56 (20130101)
C08F 220/58 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1668 (20130101) Original (OR) Class
C09D 5/1693 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045657 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Science Foundation (NSF)
APPLICANT(S) Jennifer A. Lewis (Urbana, Illinois);  Robert F. Shepherd (St. Paul, Minnesota);  Robert A. Barry, III (Beaverton, Oregon);  Sara T. Parker (Portland, Oregon);  Jennifer N. H. Shepherd (St. Paul, Minnesota);  Pierre Wiltzius (Santa Barbara, California);  Ralph G. Nuzzo (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Jennifer A. Lewis (Urbana, Illinois);  Robert F. Shepherd (St. Paul, Minnesota);  Robert A. Barry, III (Beaverton, Oregon);  Sara T. Parker (Portland, Oregon);  Jennifer N. H. Shepherd (St. Paul, Minnesota);  Pierre Wiltzius (Santa Barbara, California);  Ralph G. Nuzzo (Champaign, Illinois)
ABSTRACT A viscoelastic ink for direct writing of hydrogel structures includes a long chain polymer and a photopolymerizable moiety, which may be a photopolymerizable monomer or a photopolymerizable group attached to the long chain polymer. The ink may also include a crosslinking agent, a photoinitiator, and water. The long chain polymer is present at a concentration greater than a critical overlap concentration c* of the long chain polymer in the ink.
FILED Tuesday, March 22, 2011
APPL NO 13/636542
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/16 (20130101)
A61L 27/16 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/52 (20130101)
A61L 27/56 (20130101)

Compositions of Macromolecular Compounds
C08L 5/08 (20130101)
C08L 33/10 (20130101)
C08L 33/10 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/10 (20130101)
C09D 11/16 (20130101) Original (OR) Class
C09D 11/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045751 Place et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Robert F. Place (San Francisco, California);  Long-Cheng Li (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Robert F. Place (San Francisco, California);  Long-Cheng Li (San Francisco, California)
ABSTRACT Methods, compositions and kits are provided for increasing the expression of a gene product in a cell by contacting the cell with a modified small activating RNA (saRNA) molecule, which provides for an increase in gene expression that is improved over the increase in expression provided by traditional saRNAs. These methods and compositions find use in any application in which an increase in gene expression in a cell is desired.
FILED Thursday, April 28, 2011
APPL NO 13/096817
ART UNIT 1674 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2320/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045842 Han et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Shu-Jen Han (Cortlandt Manor, New York);  Lian Guo (Croton-on-Hudson, New York);  Xuesong Li (Wappingers Falls, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Shu-Jen Han (Cortlandt Manor, New York);  Lian Guo (Croton-on-Hudson, New York);  Xuesong Li (Wappingers Falls, New York)
ABSTRACT An electroplating etching apparatus includes a power to output current, and a container configured to contain an electrolyte. A cathode is coupled to the container and configured to fluidly communicate with the electrolyte. An anode is electrically connected to the output, and includes a graphene layer. A metal substrate layer is formed on the graphene layer, and is etched from the graphene layer in response to the current flowing through the anode.
FILED Friday, September 14, 2012
APPL NO 13/617727
ART UNIT 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 38/10 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 31/0453 (20130101)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/02 (20130101)
C25F 5/00 (20130101)
C25F 7/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045987 Levine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Jeffrey R. Levine (Vernon Rockville, Connecticut);  Dominic J. Mongillo (West Hartford, Connecticut);  Brandon S. Donnell (Hartford, Connecticut)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Jeffrey R. Levine (Vernon Rockville, Connecticut);  Dominic J. Mongillo (West Hartford, Connecticut);  Brandon S. Donnell (Hartford, Connecticut)
ABSTRACT An assembly for a gas turbine engine includes a first platform and an airfoil extending from the first platform. The airfoil includes a first fillet, pressure side biased discharge openings, and a first center cooling discharge opening. A pressure side wall of the airfoil and the first platform form an acute angle at the trailing edge. The first fillet is formed around a perimeter of the airfoil where the airfoil extends from the first platform. The pressure side biased cooling discharge openings are along the trailing edge outside of the first fillet. Each pressure side biased cooling discharge opening extends from the trailing edge along the pressure side wall. The first center cooling discharge opening extends along the trailing edge into the first fillet and is centrally located between the pressure side wall and the suction side wall.
FILED Friday, June 15, 2012
APPL NO 13/524295
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/186 (20130101)
F01D 5/187 (20130101) Original (OR) Class
F01D 9/041 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/122 (20130101)
F05D 2240/304 (20130101)
F05D 2260/202 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045998 Lo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Charles Lo (Peoria, Arizona);  Ted Alford (Mesa, Arizona);  Morris Anderson (Mesa, Arizona)
ASSIGNEE(S) HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey)
INVENTOR(S) Charles Lo (Peoria, Arizona);  Ted Alford (Mesa, Arizona);  Morris Anderson (Mesa, Arizona)
ABSTRACT A system for directing air flow to separate plena of a compartment that is defined at least by a compartment wall includes a NACA scoop, and a Pitot scoop. The NACA scoop is formed in the compartment wall, and includes two side walls, a bottom wall, and an entrance lip that is defined by the compartment wall and is spaced apart from the bottom wall to form a NACA scoop air inlet. The Pitot scoop is longitudinally aligned with the NACA scoop, includes a Pitot scoop air inlet, a Pitot scoop air outlet, and a Pitot scoop flow passage.
FILED Monday, December 12, 2011
APPL NO 13/316960
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 17/105 (20130101) Original (OR) Class

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/141 (20130101)

Jet-propulsion Plants
F02K 3/075 (20130101)
F02K 3/115 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046000 Kominsky
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Daniel Kominsky (Christiansburg, Virginia)
ASSIGNEE(S) Prime Photonics, LC (Blacksburg, Virginia)
INVENTOR(S) Daniel Kominsky (Christiansburg, Virginia)
ABSTRACT The present invention relates to systems and methods for real-time health monitoring of engines to monitor turbomachinery blades during engine operation and report anomalous behavior and shape of the blades if it occurs, such as damage by FOD. The system includes sensor(s) for obtaining a blade reflection profile from a blade passing by the sensor(s) during a revolution of the rotor in combination with a processor for performing timing calculations and/or fingerprint comparisons with reference data to identify a change in blade fingerprint relative to the reference data, which may indicate blade damage. Such systems can reduce operational costs, enhance safety and improve operational readiness by facilitating condition-based maintenance of engine rotors as opposed to schedule-based solutions. The invention can prevent the needless loss of life and assets caused by undetected minor levels of blade damage that may lead to unexpected catastrophic failure of an engine.
FILED Monday, June 18, 2012
APPL NO 13/525584
ART UNIT 2864 — Printing/Measuring and Testing
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 21/003 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2260/80 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 23/024 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/671 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046048 Malaczynski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) DELPHI TECHNOLOGIES HOLDING, S.arl (Bascharage, Luxembourg)
ASSIGNEE(S) DELPHI INTERNATIONAL OPERATIONS LUXEMBOURG, S.A.R.L. (Luxembourg, Luxembourg)
INVENTOR(S) Gerard Wladyslaw Malaczynski (Bloomfield Hills, Michigan);  Robert J.A. Van Der Poel (Schweich, Luxembourg)
ABSTRACT A method of determining fuel quality in an internal combustion engine comprises the steps of: a) sampling a signal representative of the revolution speed of said engine during a sampling window, thereby obtaining an array of samples; and b) computing a Fourier component corresponding to a predetermined index in the frequency domain and determining a fuel quality indicator therefrom. The fuel quality indicator is representative of a magnitude of the Fourier component of this predetermined index.
FILED Wednesday, October 10, 2012
APPL NO 13/648383
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Internal-combustion Piston Engines; Combustion Engines in General
F02B 3/06 (20130101)

Controlling Combustion Engines
F02D 19/0636 (20130101)
F02D 19/0649 (20130101)
F02D 41/08 (20130101)
F02D 41/0025 (20130101)
F02D 41/1497 (20130101)
F02D 45/00 (20130101) Original (OR) Class
F02D 2041/288 (20130101)
F02D 2200/101 (20130101)
F02D 2200/0612 (20130101)
F02D 2250/14 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046056 Lerg
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) Bryan H. Lerg (Westfield, Indiana)
ASSIGNEE(S) Rolls-Royce North American Technologies, Inc. (Indianapolis, Indiana)
INVENTOR(S) Bryan H. Lerg (Westfield, Indiana)
ABSTRACT Embodiments include an inlet particle separator system for a gas turbine engine. The inlet particle separator system includes an inertial particle separator that separates incoming air into a cleaned air flow and a scavenge flow. Embodiments may also include an ejector that provides a draw on a scavenge duct and entrains the scavenge flow into a charged flow, e.g., such as the output of a first stage fan. The ejector may have a variable output.
FILED Saturday, December 05, 2009
APPL NO 12/631811
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Separation
B01D 45/06 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/05 (20130101)
F02C 7/052 (20130101)
F02C 7/055 (20130101)

Jet-propulsion Plants
F02K 3/02 (20130101) Original (OR) Class
F02K 3/04 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2250/51 (20130101)
F05D 2250/411 (20130101)
F05D 2260/607 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/675 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046325 Littlestone et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Alyssa A. Littlestone (Washington, District of Columbia);  Philip J. Dudt (North Bethesda, Maryland)
ABSTRACT A composite shield comprises a panel including an outer ballistic fabric strike surface layer and an inner structural armor plate layer. The structural armor plate layer has a multiplicity of traversing ports. The traversing ports have sufficient lateral area to allow deformation of the ballistic fabric through the structural armor plate layer on the occurrence of explosive blast. The composite shield is particularly effective in protecting personnel. Blast frequencies in the damaging 1000 to 3000 Hz range are attenuated.
FILED Friday, August 23, 2013
APPL NO 13/974115
ART UNIT 3638 — Static Structures, Supports and Furniture
CURRENT CPC
Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 5/0471 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046334 Redding
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
APPLICANT(S) U.S. Army Edgewood Chemical and Biological Command (APG, Maryland)
ASSIGNEE(S) The United States of America As Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) David R. Redding (Jarrettsville, Maryland)
ABSTRACT An incendiary device such as a grenade includes a fuze; a fuze bushing operatively connected to the fuze; a first plate snap fit to the fuze bushing; a delay column pressed into the first plate; a drag adapter partially surrounding the fuze bushing and contacting a top of the first plate; a burster tube operatively connected to the first plate; a second plate operatively connected to the burster tube; and a housing body screw fit to the first plate and the second plate and surrounding the burster tube, wherein the first plate and the second plate are epoxied to the housing body and the burster tube, wherein the fuze is configured to initiate causing gases and sparks to be released between the fuze bushing and the first plate, wherein the gases and sparks increases a pressure causing the fuze and the fuze bushing to be ejected from the housing body.
FILED Friday, November 22, 2013
APPL NO 14/087559
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 27/00 (20130101)

Ammunition Fuzes; Arming or Safety Means Therefor
F42C 19/095 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046353 Michopoulos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) John G. Michopoulos (Washington, District of Columbia);  Athanasios Iliopoulos (Chevy Chase, Maryland);  Nikos P. Andrianopoulos (Athens, Greece)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) John G. Michopoulos (Washington, District of Columbia);  Athanasios Iliopoulos (Chevy Chase, Maryland);  Nikos P. Andrianopoulos (Athens, Greece)
ABSTRACT A method and system for measuring full field deformation characteristics in three dimensions of a body upon which a pattern of visible marks has been applied. The method includes receiving images of the pattern of marks from at least two digital video cameras as the specimen deforms. A computer processor identifies the centroids of each of the two camera images of the body in a first frame, matches the centroids of the marks in the two images, and generates a three-dimensional representation of the centroids based on the two images, and repeats these steps for the images from the two cameras in a subsequent frame. The computer processor calculates the displacement vector between a three dimensional representation of the centroids and the subsequent three dimensional representation of the centroids, and calculates full field displacement and strain fields based on the displacement vector.
FILED Thursday, August 02, 2012
APPL NO 13/565698
ART UNIT 2422 — Cable and Television
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/165 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/068 (20130101)
G01N 2203/0017 (20130101)
G01N 2203/0218 (20130101)
G01N 2203/0647 (20130101)

Image Data Processing or Generation, in General
G06T 7/0075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046411 Wang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Defense Sciences Office (DSO)
APPLICANT(S) Guanghua Wang (Clifton Park, New York);  Anquan Wang (West Chester, Ohio);  Nirm Velumylum Nirmalan (Niskayuna, New York);  Jordi Estevadeordal (Saratoga Springs, New York);  Sean Patrick Harper (Mason, Ohio);  Bradford Allen Lewandowski (West Chester, Ohio)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) Guanghua Wang (Clifton Park, New York);  Anquan Wang (West Chester, Ohio);  Nirm Velumylum Nirmalan (Niskayuna, New York);  Jordi Estevadeordal (Saratoga Springs, New York);  Sean Patrick Harper (Mason, Ohio);  Bradford Allen Lewandowski (West Chester, Ohio)
ABSTRACT An optical sensor system includes a multi-color pyrometer in optical communication with a component. The pyrometer generates signals at least partially representative of radiation received from the component and from soot particles. The system includes at least one processing unit coupled to the pyrometer. The processing unit is programmed to receive the signals and distinguish portions of radiation received between at least two wavelength bands. The processing unit is also programmed to determine that a first portion of radiation within a first of the wavelength bands is representative of a temperature of soot particles and that a second portion of radiation within a second of the wavelength bands is representative of a temperature of the component. The processing unit is further programmed to filter out signals representative of the first portion of the radiation.
FILED Monday, November 14, 2011
APPL NO 13/295838
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 17/08 (20130101)
F01D 17/20 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2270/804 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/026 (20130101)
G01J 5/0088 (20130101) Original (OR) Class
G01J 5/602 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046422 Kudenov
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S) Michael W. Kudenov (Tucson, Arizona)
ASSIGNEE(S) The Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Michael W. Kudenov (Tucson, Arizona)
ABSTRACT Snapshot imaging Fourier transform spectrometers include a lens array that produces sub-images that are directed through a birefringent interferometer in orthogonal polarization eigenstates that acquire an optical path difference. Interference patterns based on this OPD can be Fourier transformed to obtain a spectral image. In some examples, polarizing gratings provide a spatial heterodyne frequency and offset the spectra.
FILED Friday, April 20, 2012
APPL NO 13/452686
ART UNIT 2886 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0208 (20130101)
G01J 3/0229 (20130101)
G01J 3/447 (20130101)
G01J 3/2803 (20130101)
G01J 3/4531 (20130101) Original (OR) Class
G01J 2003/452 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046450 Lee et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Mitchell J. Lee (Scottsdale, Arizona);  Nicklaus Cummings Kimball (Mesa, Arizona)
ABSTRACT A coupon geometry that reliably fails in the gauge area of the coupon during fatigue testing. The propensity to fail at the gauge area is imparted by using a bow-tie-shaped coupon coupled with similarly shaped tabs. The test coupons have a bow-tie-shaped profile with tapered sides that converge as they extend from the opposing ends of the coupon to the gauge area, forming a pair of trapezoidal portions (one the mirror image of the other) connected by the gauge area. These trapezoidal portions of the test coupon include the regions where similarly trapezoidal tabs will be adhered to the front and back of the coupon. The test coupon has a minimum width in the gauge area and a constant thickness, and a height of the gauge area is no greater than 3% of a height of the test coupon.
FILED Monday, February 18, 2013
APPL NO 13/769485
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/02 (20130101) Original (OR) Class
G01N 3/08 (20130101)
G01N 3/60 (20130101)
G01N 2203/0073 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046483 Denison et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Timothy J. Denison (Andover, Massachusetts);  Alexis Sauer-Budge (Brighton, Massachusetts);  Jene A. Golovchenko (Lexington, Massachusetts);  Amit Meller (Newton, Massachusetts);  Eric Brandin (Portsmouth, New Hampshire);  Daniel Branton (Lexington, Massachusetts)
ABSTRACT The invention relates to a method for characterizing a target polynucleic acid by providing a surface containing a channel of a dimension sufficient to allow sequential monomer-by-monomer passage of a single-stranded polynucleic acid, but not of a double-stranded polynucleic acid; providing a source of hybridized target polynucleic acid at the surface; inducing passage of the target polynucleic acid through the channel, whereby the target polynucleic acid undergoes base pair separation (melts) prior to its passage; and making one or more measurements over time as the target polynucleic acid moves relative to the channel yielding data suitable to determine a monomer-dependent characteristic of the target polynucleic acid.
FILED Thursday, August 08, 2013
APPL NO 13/962141
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/631 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/447 (20130101) Original (OR) Class
G01N 33/48721 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046508 Genovese et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) U.S. Army Research Development and Engineering Command (APG, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) James A. Genovese (Street, Maryland);  Amee W. LaBonte (Havre de Grace, Maryland);  Joseph A Domanico (Bel Air, Maryland);  Michael F. Kauzlarich (Edgewood, Maryland)
ABSTRACT The present invention can be characterized as a trainer kit for a Colorimetric Reconnaissance Explosive Squad Screening (“CRESS”) kit, which contains a control compound and a set of simulated explosive compositions (“SEC”). The control compound contains no explosive precursor, while each SEC is a combination of one or more explosive precursors that is to be detected by CRESS, and at least one non-explosive additive that reduces the kinetics of the explosive precursor. The SEC retains the colorimetric characteristics of the explosive precursor, but is stable in heat and non-hazardous.
FILED Thursday, March 14, 2013
APPL NO 13/804531
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/22 (20130101)
G01N 33/227 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 436/00 (20150115)
Y10T 436/10 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046541 Kubena et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) HRL LABORATORIES LLC (Malibu, California);  The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California);  The Boeing Company (Chicago, Illinois)
INVENTOR(S) Randall L. Kubena (Oak Park, California);  David T. Chang (Calabasas, California);  Robert L. Larson (West Seattle, California)
ABSTRACT A method for producing a disk resonator gyroscope includes providing a base substrate and a handle wafer with a release hole, bonding a release wafer to the handle wafer, bonding a resonator wafer to the release wafer, etching the resonator wafer to form a disk resonator with a central pillar, and sense and drive electrodes, selectively applying a conductive film onto the disk resonator on a side of the disk resonator opposite the release wafer, on the outer edge of the disk resonator, and on the surfaces of the sense and drive electrodes facing the outer edge of the disk resonator, bonding the sense and drive electrodes and the central pillar of the disk resonator to the base substrate, and releasing the handle wafer by introducing a dry release agent into the release hole to undercut the release wafer.
FILED Tuesday, October 09, 2012
APPL NO 13/648041
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 1/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046565 Collins, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Thomas E. Collins, III (Tyngsboro, Massachusetts);  Gregory M. Flewelling (Merrimack, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Thomas E. Collins, III (Tyngsboro, Massachusetts);  Gregory M. Flewelling (Merrimack, New Hampshire)
ABSTRACT Techniques for performing built-in self-test (BIST) of performance of an RF system are disclosed. The techniques may be used, for example, for measuring distortion generated by the RF system under test, detecting faults in the system, determining calibration of the system, and/or assisting in compensating analog circuitry that is sensitive to temperature, supply voltage, and/or process variations. Also, a BIST architecture for determining RF performance of an RF systems is disclosed.
FILED Monday, August 29, 2011
APPL NO 13/220154
ART UNIT 2866 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/2822 (20130101) Original (OR) Class
G01R 31/3187 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046627 Ravela
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Srinivas Ravela (Belmont, Massachusetts)
ABSTRACT A method for generating a coalesced image includes receiving a plurality of fields for a geographical region. A set of forces is determined for each of the fields by multiplying a gradient of a respective one of the fields with a difference between the respective one of the fields and each of the other fields. A net influence for each field is determined by averaging each of the forces associated with the respective field. A spectral filter is applied to each net influence to generate a respective value of a mode of motion used to deform each field and then displace each field until each field coalesces with each other field.
FILED Wednesday, May 29, 2013
APPL NO 13/904058
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Meteorology
G01W 1/10 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 7/2066 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046647 Bravo-Abad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Jorge Bravo-Abad (Madrid, Spain);  John D. Joannopoulos (Belmont, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jorge Bravo-Abad (Madrid, Spain);  John D. Joannopoulos (Belmont, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT The dielectric, three-dimensional photonic materials disclosed herein feature Dirac-like dispersion in quasi-two-dimensional systems. Embodiments include a face-centered cubic (fcc) structure formed by alternating layers of dielectric rods and dielectric slabs patterned with holes on respective triangular lattices. This fcc structure also includes a defect layer, which may comprise either dielectric rods or a dielectric slab with patterned with holes. This defect layer introduces Dirac cone dispersion into the fcc structure's photonic band structure. Examples of these fcc structures enable enhancement of the spontaneous emission coupling efficiency (the β-factor) over large areas, contrary to the conventional wisdom that the β-factor degrades as the system's size increases. These results enable large-area, low-threshold lasers; single-photon sources; quantum information processing devices; and energy harvesting systems.
FILED Tuesday, February 19, 2013
APPL NO 13/769954
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101)
G02B 6/1225 (20130101) Original (OR) Class
G02B 2006/1213 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046680 Cui et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Xiquan Cui (Pasadena, California);  Changhuei Yang (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Xiquan Cui (Pasadena, California);  Changhuei Yang (Pasadena, California)
ABSTRACT A microscopy method and configuration provides the ability to achieve wide field view and high resolution simultaneously. A beam array generator generates an M×N light beam array that illuminates a sample and an M×N sensor array. The sensor array obtains a whole microscopy image of the sample based on the light beam array. Each light beam of the array corresponds to one unique pixel sensor in the sensor array. A scanning of all light beams of the light beam array covers a whole area of the sample.
FILED Friday, March 06, 2009
APPL NO 12/399823
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 21/0024 (20130101) Original (OR) Class
G02B 21/0032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046891 Busch et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Darryl Busch (Eden Prairie, Minnesota);  Raj Mohan Bharadwaj (Maple Grove, Minnesota)
ASSIGNEE(S) HONEYWELL INTERNATIONAL INC. (Morristown, New Jersey)
INVENTOR(S) Darryl Busch (Eden Prairie, Minnesota);  Raj Mohan Bharadwaj (Maple Grove, Minnesota)
ABSTRACT A system and method for determining the response capabilities of a control effector are provided. Command data and sensor data associated with the control effector are processed to generate control effector health data representative of control effector health. The control effector health data are processed in a reasoned. The reasoned is configure to selectively indict and clear one or more faults, determine one or more failures that cause indicted faults, and determine, based on the one or more determined failures, a usable range of control effector commands to which the control effector can respond.
FILED Tuesday, August 16, 2011
APPL NO 13/211019
ART UNIT 2864 — Printing/Measuring and Testing
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 23/0256 (20130101)
G05B 23/0278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047153 Bradley
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) William Bradley (Somerville, Massachusetts)
ASSIGNEE(S) ANALOG DEVICES, INC. (Norwood, Massachusetts)
INVENTOR(S) William Bradley (Somerville, Massachusetts)
ABSTRACT Circuitry for stochastic computation includes processing nodes, including a first processing node and a second processing node, each configured to process an outcome stream having a plurality of outcomes, each outcome being in one of a plurality of states, wherein an outcome from said outcome stream is in a particular state with a particular probability; communication links configured to transmit outcome streams between pairs of said processing nodes; and a delay module on each of said communication links, said delay module configured to delay outcome streams traversing said communication link by an assigned delay; wherein said first and second processing nodes are connected by a plurality of data paths, at least one of which comprises a plurality of communication links, each of said data paths causing an aggregate delay to an outcome stream traversing said data path; wherein no two aggregate delays impose the same delay on an outcome stream.
FILED Tuesday, February 22, 2011
APPL NO 13/032511
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 7/588 (20130101) Original (OR) Class

Coding; Decoding; Code Conversion in General
H03M 13/1102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047571 Miller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Warner A. Miller (Boca Raton, Florida);  Grigoriy Kreymerman (Pembroke Pines, Florida);  Paul M. Alsing (Chittenango, New York)
ASSIGNEE(S) FLORIDA ATLANTIC UNIVERSITY (Boca Raton, Florida)
INVENTOR(S) Warner A. Miller (Boca Raton, Florida);  Grigoriy Kreymerman (Pembroke Pines, Florida);  Paul M. Alsing (Chittenango, New York)
ABSTRACT Encoding of quantum algorithm and devices therefrom are provided. The encoding includes receiving a unitary matrix operator representing the quantum algorithm, each row of the unitary matrix operator defining a superposition of basis state vectors for transforming input states to output states. The encoding also includes recording rows of the unitary matrix operator by applying, to a volume holographic element, a combination of an ith one of n reference waves and a superposition of n signal waves defined by the superposition defined in an ith row of the unitary matrix operator. The n signal waves are a first set of n plane waves lying on a first conical surface having a first half angle and the n reference waves are a second set of n plane waves lying on a second conical surface, concentric with the first conical surface, with a second half angle different that the first half angle.
FILED Friday, April 20, 2012
APPL NO 13/451638
ART UNIT 2872 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Holographic Processes or Apparatus
G03H 1/0005 (20130101)
G03H 1/0248 (20130101)
G03H 1/265 (20130101)

Computer Systems Based on Specific Computational Models
G06N 99/002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047818 Day et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Jacob Day (Wylie, Texas);  Jing Li (Lubbock, Texas);  Donald Lie (Lubbock, Texas);  Zhaoyang Fan (Lubbock, Texas);  Jingyu Lin (Lubbock, Texas);  Hongxing Jiang (Lubbock, Texas)
ASSIGNEE(S) III-N Technology, Inc. (Lubbock, Texas)
INVENTOR(S) Jacob Day (Wylie, Texas);  Jing Li (Lubbock, Texas);  Donald Lie (Lubbock, Texas);  Zhaoyang Fan (Lubbock, Texas);  Jingyu Lin (Lubbock, Texas);  Hongxing Jiang (Lubbock, Texas)
ABSTRACT An active matrix microdisplay system is provided. The microdisplay system includes an array of micro-emitters. The microdisplay system also includes an array of CMOS driving circuits. Each of the CMOS driving circuits is coupled to a respective micro-emitter for controlling current to each respective micro-emitter. Each driving circuit includes metal-oxide-semiconductor field-effect transistor (MOSFET) devices, where the MOSFET devices comprise p-type metal-oxide-semiconductors (PMOSs) or n-type metal-oxide-semiconductors (NMOSs).
FILED Saturday, March 12, 2011
APPL NO 13/046725
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information
G09G 3/3233 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047881 Edelstein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Alan S. Edelstein (Alexandria, Virginia);  Jonathan R. Petrie (Columbia, Maryland)
ABSTRACT A method and system for storing information in a nonvolatile memory comprising: a substrate comprising magnetic material operatively associated therewith, the magnetic material having at least one first portion of low permeability and at least one second portion of high permeability; a reader comprising a sensor for reading information by measuring the magnetic permeability for the at least one first portion and the at least one second portion; whereby the at least one first and second portions are subjected to a magnetic probe field from one of an external source, the sensor, or a combination of an external source and the sensor.
FILED Friday, December 21, 2012
APPL NO 13/725473
ART UNIT 2686 — Selective Visual Display Systems
CURRENT CPC
Information Storage Based on Relative Movement Between Record Carrier and Transducer
G11B 5/09 (20130101) Original (OR) Class
G11B 5/33 (20130101)
G11B 5/332 (20130101)
G11B 11/14 (20130101)

Static Stores
G11C 11/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047950 Amiri et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Pedram Khalili Amiri (Los Angeles, California);  Richard Dorrance (Santa Monica, California);  Dejan Markovic (Los Angeles, California);  Kang L. Wang (Santa Monica, California)
ABSTRACT Voltage controlled magnetoelectric tunnel junction (MEJ) based content addressable memory is described which provides efficient high speed switching of MEJs toward eliminating any read disturbance of written data. Each cell of said CAM having two MEJs and transistor circuitry for performing a write at voltages of a first polarity, and reads at voltages of a second polarity. If the data searched does not equal the data written in the CAM, then the match line state is changed.
FILED Friday, August 30, 2013
APPL NO 14/014783
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 11/5607 (20130101)
G11C 13/004 (20130101)
G11C 15/02 (20130101) Original (OR) Class
G11C 15/046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048179 Abraham et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Margaret H. Abraham (Portola Valley, California);  David P. Taylor (Hawthorne, California)
ABSTRACT Systems and methods for preparing films using sequential ion implantation, and films formed using same, are provided herein. A structure prepared using ion implantation may include a substrate; an embedded structure having pre-selected characteristics; and a film within or adjacent to the embedded structure and including ions having a perturbed arrangement arising from the presence of the embedded structure. The perturbed arrangement may include the ions being covalently bonded to each other, to the embedded structure, or to the substrate, whereas the ions instead may be free to diffuse through the substrate in the absence of the embedded structure. The embedded structure may inhibit or impede the ions from diffusing through the substrate, such that the ions instead covalently bond to each other, to the embedded structure, or to the substrate. The film may include, for example, diamond-like carbon, graphene, or SiC having a pre-selected phase.
FILED Thursday, November 21, 2013
APPL NO 14/086826
ART UNIT 2883 — Optics
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/10 (20130101)
C23C 14/48 (20130101)
C23C 14/0635 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/1347 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/265 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048378 Shatalov et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Maxim S. Shatalov (Columbia, South Carolina);  Alexander Dobrinsky (Providence, Rhode Island);  Michael Shur (Latham, New York);  Remigijus Gaska (Columbia, South Carolina)
ASSIGNEE(S) Sensor Electronic Technology, Inc. (Columbia, South Carolina)
INVENTOR(S) Maxim S. Shatalov (Columbia, South Carolina);  Alexander Dobrinsky (Providence, Rhode Island);  Michael Shur (Latham, New York);  Remigijus Gaska (Columbia, South Carolina)
ABSTRACT An interface including roughness components for improving the propagation of radiation through the interface is provided. The interface includes a first profiled surface of a first layer comprising a set of large roughness components providing a first variation of the first profiled surface having a first characteristic scale and a second profiled surface of a second layer comprising a set of small roughness components providing a second variation of the second profiled surface having a second characteristic scale. The first characteristic scale is approximately an order of magnitude larger than the second characteristic scale. The surfaces can be bonded together using a bonding material, and a filler material also can be present in the interface.
FILED Friday, June 15, 2012
APPL NO 13/524350
ART UNIT 2896 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 33/20 (20130101) Original (OR) Class
H01L 33/22 (20130101)
H01L 2933/0083 (20130101)
H01L 2933/0091 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/0224 (20130101)
H01S 5/34333 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048521 Larsen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Christopher George Larsen (Cincinnati, Ohio);  Richard Allan Roth, II (Goshen, Ohio);  Stuart James Shelley (Cincinnati, Ohio);  Aaron Collins Hacker (Cincinnati, Ohio);  Adam Jacob Hehr (Port Clinton, Ohio)
ASSIGNEE(S) Etegent Technologies, Ltd. (Cincinnati, Ohio)
INVENTOR(S) Christopher George Larsen (Cincinnati, Ohio);  Richard Allan Roth, II (Goshen, Ohio);  Stuart James Shelley (Cincinnati, Ohio);  Aaron Collins Hacker (Cincinnati, Ohio);  Adam Jacob Hehr (Port Clinton, Ohio)
ABSTRACT A broadband waveguide incorporates various reflection suppression techniques to reduce reflections in signals communicated thereby. The waveguide includes one or more filaments that each include a first and second end. A first matrix may be configured proximate the first end(s) while a second matrix may be configured proximate an intermediate location between the first and second ends. A damping material may cover a portion of the filament(s) that extends from the second matrix to the second end(s) (including the second end(s) themselves) and/or the second end(s) of the filament(s) is/are shaped to at least partially suppress reflections of the signal therefrom. When configured with multiple filaments, at least two of the filaments may have differing lengths that extend from the second matrix and also operate to at least partially suppress reflections of a signal.
FILED Thursday, March 24, 2011
APPL NO 13/071159
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/2462 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/06 (20130101) Original (OR) Class
H01P 5/026 (20130101)
H01P 5/085 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49004 (20150115)
Y10T 29/49016 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048625 Zhou et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Heng Zhou (New York, New York);  Shu-Wei Huang (New York, New York);  Chee Wei Wong (Weehawken, New Jersey)
ABSTRACT Normal group velocity dispersion mode-locked optical frequency combs are provided on-chip. On-chip coherent frequency comb generation includes pulses showing temporal durations of about 74 fs. Pump detuning and bandpass filtering are provided for stabilizing and shaping the pulses from normal group velocity dispersion microresonators.
FILED Tuesday, July 29, 2014
APPL NO 14/445959
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/1106 (20130101) Original (OR) Class
H01S 3/08013 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048720 Ortiz
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Joe Anthony Ortiz (Garden Grove, California)
ABSTRACT A bidirectional low voltage power supply (LVPS) for providing power to motor drive electronics. The bidirectional LVPS includes two simple, discrete converters. A first converter is used to provide power to an output and the second converter recycles power from the output to the power source. The first converter powers the drive electronics which drives the motor. During an operating process, the first converter shuts off and the second converter turns on to recycle power from the motor to the power source.
FILED Tuesday, April 02, 2013
APPL NO 13/855298
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 1/02 (20130101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/00 (20130101) Original (OR) Class
H02M 1/088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048761 Roberts et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) M. Joseph Roberts (Ridgecrest, California);  Alfred J. Baca (Ridgecrest, California);  William W. Lai (Ridgecrest, California);  Lawrence C. Baldwin (Ridgecrest, California);  Michael T. Owens (Ridgecrest, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) M. Joseph Roberts (Ridgecrest, California);  Alfred J. Baca (Ridgecrest, California);  William W. Lai (Ridgecrest, California);  Lawrence C. Baldwin (Ridgecrest, California);  Michael T. Owens (Ridgecrest, California)
ABSTRACT An energy harvesting device using auxetic materials includes a first auxetic conductive electrode layer. A second auxetic conductive electrode layer is associated with the first auxetic conductive electrode layer. The auxetic conductive electrode layers have negative Poisson ratios. At least one dielectric elastomer layer is associated in layered orientation between the first and second auxetic conductive electrode layers.
FILED Thursday, July 19, 2012
APPL NO 13/553638
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Ignition; Extinguishing-devices
F23Q 3/002 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048762 Finkel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Peter Finkel (Andover, Massachusetts);  Ahmed H Amin (North Attleboro, Massachusetts);  Colin J Murphy (Newport, Rhode Island);  Christopher S Lynch (Sherman, California);  Wen D Wong (Los Angeles, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Peter Finkel (Andover, Massachusetts);  Ahmed H Amin (North Attleboro, Massachusetts);  Colin J Murphy (Newport, Rhode Island);  Christopher S Lynch (Sherman, California);  Wen D Wong (Los Angeles, California)
ABSTRACT A transducer for generating electrical energy from an expected force includes a single crystal ferroelectric material having a phase transition stress level. Mechanical stress is provided to this crystal at a level approaching the phase transition stress level, such that the expected external force will cause the phase transition. At least two electrodes are joined to the single crystal for receiving electrical energy created by the phase transition. The electrodes can be joined to conditioning and storage circuitry. In further embodiments, the phase transition is induced by an expected temperature change.
FILED Thursday, March 14, 2013
APPL NO 13/826109
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/18 (20130101)
H01L 41/187 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/009 (20130101)
H02N 2/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048767 Rozman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Gregory I. Rozman (Rockford, Illinois);  Thomas A. Duclos (Suffield, Connecticut);  Duane A. James (Middletown, Connecticut)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Windsor Locks, Connecticut)
INVENTOR(S) Gregory I. Rozman (Rockford, Illinois);  Thomas A. Duclos (Suffield, Connecticut);  Duane A. James (Middletown, Connecticut)
ABSTRACT A pulse-width modulation (PWM) inverter controller compensates for harmonics in the output current provided by a PWM inverter to permanent magnet (PM) motor. The PWM inverter controller includes a field-oriented controller (FOC) that monitors output currents provided by the PWM inverter to the PM motor and employs the monitored output currents in a current loop feedback that generates control signals. A harmonic compensator transforms monitored phase currents into rectangular waveforms having magnitudes modified based on detected harmonics within the monitored phase currents to generate compensation signals. The compensation signals generated by the harmonic compensator are summed with the control signals generated by the FOC to generate compensated control signals. A PWM signal generator generates PWM signals for controlling the PWM inverter based on the compensated control signals.
FILED Monday, January 23, 2012
APPL NO 13/356348
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 6/10 (20130101) Original (OR) Class
H02P 21/14 (20130101)
H02P 21/0035 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048807 Pereira Da Cunha et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Mauricio Pereira Da Cunha (Orono, Maine);  Bennet Meulendyk (Manchester, Maine)
ASSIGNEE(S) University of Maine System Board of Trustees (Bangor, Maine)
INVENTOR(S) Mauricio Pereira Da Cunha (Orono, Maine);  Bennet Meulendyk (Manchester, Maine)
ABSTRACT Surface acoustic wave resonators for use in high temperature applications including a piezoelectric substrate, at least one interdigital transducer supported by the piezoelectric substrate, and a grating reflector supported by the piezoelectric substrate, the grating reflector being fabricated of a heavy metal and comprising a plurality of electrodes, at least one electrode of the plurality of electrodes being electrically isolated from at least one other electrode. Methods of making surface acoustic wave resonators are also included.
FILED Thursday, March 17, 2011
APPL NO 13/050389
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Impedance Networks, e.g Resonant Circuits; Resonators
H03H 9/02834 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048935 Niesen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Alcatel-Lucent USA Inc. (Murray Hill, New Jersey)
ASSIGNEE(S) Alcatel Lucent (Boulogne-Billancourt, France)
INVENTOR(S) Urs Niesen (Summit, New Jersey);  Piyush Gupta (Bridgewater, New Jersey);  Yu-Chih Huang (College Station, Texas)
ABSTRACT A system including a transmitter and a receiver that are loosely synchronized, the transmitter encodes signal waveforms having a start time, a width and a height that are determined based on a range of possible relative drifts of a receiver clock with respect to a transmitter clock and the receiver decodes the waveforms based on a sequence of tests, chosen to account for any uncertainty that may arise due to the lack of tight synchronization.
FILED Friday, January 25, 2013
APPL NO 13/750213
ART UNIT 2632 — Digital Communications
CURRENT CPC
Transmission
H04B 1/69 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 25/4902 (20130101)
H04L 25/4904 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048954 Rylyakov et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Alexander V. Rylyakov (Mount Kisco, New York);  Clint L. Schow (Ossining, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Alexander V. Rylyakov (Mount Kisco, New York);  Clint L. Schow (Ossining, New York)
ABSTRACT In one embodiment, the invention provides an optical interconnect comprising a transmitter for generating and transmitting an optical signal, a receiver for receiving the optical signal from the transmitter and for converting the received optical signal to an electrical signal, and a pre-transmitter distort circuit for applying a pre-transmitter distort signal to the transmitter to adjust the shape of the optical signal generated by the transmitter. Distortions are introduced into the optical signal when the optical signal is generated, transmitted to the receiver, and converted to the electrical signal. As a result of the signal applied to the transmitter by the pre-transmitter distort circuit, the optical signal generated by the transmitter has distortions to compensate for the distortions introduced into the optical signal, wherein the electrical signal, into which the optical signal is converted, has a desired shape.
FILED Wednesday, March 02, 2011
APPL NO 13/039003
ART UNIT 2634 — Digital Communications
CURRENT CPC
Transmission
H04B 10/2507 (20130101) Original (OR) Class
H04B 10/25073 (20130101)
H04B 10/25137 (20130101)
H04B 2210/254 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09049112 Chan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Uman Chan (Wappingers Falls, New York);  Deryck X. Hong (Jackson Heights, New York);  Tsai-Yang Jea (Poughkeepsie, New York);  Chulho Kim (Poughkeepsie, New York);  Zenon J. Piatek (Poughkeepsie, New York);  Hung Q. Thai (Poughkeepsie, New York);  Abhinav Vishnu (Kennewick, Washington);  Hanhong Xue (Poughkeepsie, New York)
ABSTRACT A message flow controller limits a process from passing a new message in a reliable message passing layer from a source node to at least one destination node while a total number of in-flight messages for the process meets a first level limit. The message flow controller limits the new message from passing from the source node to a particular destination node from among a plurality of destination nodes while a total number of in-flight messages to the particular destination node meets a second level limit. Responsive to the total number of in-flight messages to the particular destination node not meeting the second level limit, the message flow controller only sends a new packet from among at least one packet for the new message to the particular destination node while a total number of in-flight packets for the new message is less than a third level limit.
FILED Friday, April 05, 2013
APPL NO 13/857462
ART UNIT 2441 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 9/546 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/08 (20130101) Original (OR) Class
H04L 47/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09049136 Tetteh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
ASSIGNEE(S) Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S) William Nii Tetteh (Cambridge, Massachusetts);  Christophe Jean-Claude Merlin (Malden, Massachusetts)
ABSTRACT A system, method and apparatus arranged for efficient usage of network resources. Embodiments include nodes linked together, and the links having differing costs, e.g., bandwidth, frequency, and/or monetary cost, or any combination of these. Embodiments may identify neighboring nodes as either next-hop-neighbors or non-next-hop-neighbors. Next-hop-neighbors lie on the shortest path to any node, while non-next-hop-neighbors are nodes linked directly to a node, but the link is more costly than an alternative multi-hop path to the same node. Accordingly, embodiments may suppress packets to the non-next-hop-neighbors.
FILED Thursday, March 07, 2013
APPL NO 13/788092
ART UNIT 2414 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/15 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09049225 Jana et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Suman Jana (Austin, Texas);  Sneha Kasera (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Suman Jana (Austin, Texas);  Sneha Kasera (Salt Lake City, Utah)
ABSTRACT Identifying valid wireless access points based on clock skews. A computing device receives plurality of frames, each including a corresponding timestamp, from a wireless access point. The computing device calculates transmit and receive offsets based on transmit and receive times of the plurality of frames, and also calculates differences between the transmit and receive offsets. The computing device also calculates a clock skew of a clock at the wireless access point based on a slope of the differences. The client computing device determines whether the wireless access point is an authorized wireless access point or an unauthorized wireless access point based on comparing the calculated clock skew with one or more known baseline clock skews of one or more authorized wireless access points.
FILED Friday, September 11, 2009
APPL NO 13/063687
ART UNIT 2475 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1441 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 12/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 09044299 Britton, Jr. et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Charles L. Britton, Jr. (Alcoa, Tennessee);  Brian R. D'urso (Clinton, Tennessee);  Edward Chaum (Memphis, Tennessee);  John T. Simpson (Clinton, Tennessee);  Justin S. Baba (Knoxville, Tennessee);  M. Nance Ericson (Knoxville, Tennessee);  Robert J. Warmack (Knoxville, Tennessee)
ABSTRACT In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a Bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the Bowman's layer of the eye that are of micro-scale or less. In another embodiment, the present invention provides a method and device for drug delivery. In one embodiment, the device includes an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods, wherein the sharp feature includes a treated surface for delivering a chemical compound to the eye.
FILED Tuesday, November 05, 2013
APPL NO 14/072370
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 2017/320004 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/007 (20130101) Original (OR) Class
A61F 9/0017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044445 Korber et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S) Bette T. Korber (Los Alamos, New Mexico);  William Fischer (Sante Fe, New Mexico);  Norman Letvin (Boston, Massachusetts);  Hua-Xin Liao (Durham, North Carolina);  Barton F. Haynes (Durham, North Carolina);  Beatrice H. Hahn (Birmingham, Alabama)
ASSIGNEE(S) LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico);  BETH ISRAEL DEACONESS MEDICAL CENTER (Boston, Massachusetts);  DUKE UNIERSITY (Durham, North Carolina);  THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
INVENTOR(S) Bette T. Korber (Los Alamos, New Mexico);  William Fischer (Sante Fe, New Mexico);  Norman Letvin (Boston, Massachusetts);  Hua-Xin Liao (Durham, North Carolina);  Barton F. Haynes (Durham, North Carolina);  Beatrice H. Hahn (Birmingham, Alabama)
ABSTRACT The present invention relates, in general, to an immunogenic composition (e.g., a vaccine) and, in particular, to a polyvalent immunogenic composition, such as a polyvalent HIV vaccine containing nucleic acids encoding HIV-1 gag mosaic proteins, and to methods of using same. The invention further relates to methods that use a genetic algorithm to create sets of polyvalent antigens suitable for use, for example, in vaccination strategies.
FILED Friday, August 14, 2009
APPL NO 12/737761
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/21 (20130101) Original (OR) Class
A61K 2039/53 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/24143 (20130101)
C12N 2740/16122 (20130101)
C12N 2740/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044514 Xu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) Ting Xu (Berkeley, California);  He Dong (Albany, California);  Jessica Shu (San Francisco, California)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Ting Xu (Berkeley, California);  He Dong (Albany, California);  Jessica Shu (San Francisco, California)
ABSTRACT The present invention provides a conjugate having a peptide with from about 10 to about 100 amino acids, wherein the peptide adopts a helical structure. The conjugate also includes a first polymer covalently linked to the peptide, and a hydrophobic moiety covalently linked to the N-terminus of the peptide, wherein the hydrophobic moiety comprises a second polymer or a lipid moiety. The present invention also provides helix bundles form by self-assembling the conjugates, and particles formed by self-assembling the helix bundles. Methods of preparing the helix bundles and particles are also provided.
FILED Tuesday, September 11, 2012
APPL NO 13/610637
ART UNIT 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/42 (20130101) Original (OR) Class
A61K 47/488 (20130101)
A61K 47/48038 (20130101)
A61K 47/48215 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
Y10S 977/906 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044715 Way et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
APPLICANT(S) J. Douglas Way (Boulder, Colorado);  Paul Thoen (Littleton, Colorado);  Sabina K. Gade (Westminster, Colorado)
ASSIGNEE(S) Colorado School of Mines (Golden, Colorado)
INVENTOR(S) J. Douglas Way (Boulder, Colorado);  Paul Thoen (Littleton, Colorado);  Sabina K. Gade (Westminster, Colorado)
ABSTRACT The invention provides support-free palladium membranes and methods of making these membranes. Single-gas testing of the unsupported foils produced hydrogen permeabilities equivalent to thicker membranes produced by cold-rolling. Defect-free films as thin as 7.2 microns can be fabricated, with ideal H2/N2 selectivities as high as 40,000. Homogeneous membrane compositions may also be produced using these methods.
FILED Friday, August 22, 2008
APPL NO 12/197218
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 67/0069 (20130101)
B01D 71/022 (20130101) Original (OR) Class
B01D 2325/20 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/505 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/38 (20130101)
C23C 18/44 (20130101)
C23C 18/1605 (20130101)
C23C 18/1651 (20130101)
C23C 18/1657 (20130101)
C23C 18/1692 (20130101)
C23C 18/1841 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044739 Janke et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Christopher J. Janke (Oliver Springs, Tennessee);  Sheng Dai (Knoxville, Tennessee);  Yatsandra Oyola (Oak Ridge, Tennessee)
ABSTRACT Foam-based adsorbents and a related method of manufacture are provided. The foam-based adsorbents include polymer foam with grafted side chains and an increased surface area per unit weight to increase the adsorption of dissolved metals, for example uranium, from aqueous solutions. A method for forming the foam-based adsorbents includes irradiating polymer foam, grafting with polymerizable reactive monomers, reacting with hydroxylamine, and conditioning with an alkaline solution. Foam-based adsorbents formed according to the present method demonstrated a significantly improved uranium adsorption capacity per unit weight over existing adsorbents.
FILED Thursday, March 27, 2014
APPL NO 14/226956
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/265 (20130101) Original (OR) Class
B01J 20/28023 (20130101)
B01J 20/28033 (20130101)
B01J 45/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/28 (20130101)
C08J 7/16 (20130101)
C08J 9/36 (20130101)

Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads
D02G 3/22 (20130101)
D02G 3/34 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 10/008 (20130101)
D06M 11/63 (20130101)
D06M 14/28 (20130101)
D06M 15/31 (20130101)
D06M 15/263 (20130101)
D06M 2101/20 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2973 (20150115)
Y10T 428/2978 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044801 Golovashchenko et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Ford Global Technologies, LLC (Dearborn, Michigan)
ASSIGNEE(S) Ford Global Technologies, LLC (Dearborn, Michigan)
INVENTOR(S) Sergey Fedorovich Golovashchenko (Beverly Hills, Michigan);  John Joseph Francis Bonnen (Milford, Michigan);  Scott Alwyn Dawson (Rochester, Michigan);  Rodrigue Narainen (Rochester Hills, Michigan);  Alexander Mamutov (Dearborn, Michigan);  Andrew DiVeto (Plymouth, Michigan)
ABSTRACT A method of manufacturing a drawn panel and a die set. The method includes clamping a blank between a binder and a die that defines a cavity. A first draw punch contacts the blank in advance of a second punch that subsequently engages the blank. A central area of the blank is drawn by the first draw punch that clamps a central area of the blank against a lower die. Side areas of the blank are drawn into the cavity by the side punches while the central punch clamps the blank again the lower die.
FILED Monday, October 21, 2013
APPL NO 14/058624
ART UNIT 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal
B21D 22/06 (20130101) Original (OR) Class
B21D 24/005 (20130101)
B21D 26/021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045387 Yaghi et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
Department of Energy (DOE)
APPLICANT(S) Omar M. Yaghi (Los Angeles, California);  Alexander U. Czaja (Dirmstein, Germany);  Bo Wang (Beijing, China PRC);  Zheng Lu (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  BASF SE (Ludwigshafen, Germany)
INVENTOR(S) Omar M. Yaghi (Los Angeles, California);  Alexander U. Czaja (Dirmstein, Germany);  Bo Wang (Beijing, China PRC);  Zheng Lu (Los Angeles, California)
ABSTRACT The disclosure provides methods for the use of open metal frameworks to catalyze coupling reactions.
FILED Tuesday, July 27, 2010
APPL NO 13/387598
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 1/321 (20130101)
C07C 1/321 (20130101)
C07C 15/14 (20130101)
C07C 17/263 (20130101)
C07C 17/263 (20130101)
C07C 25/18 (20130101)
C07C 201/12 (20130101) Original (OR) Class
C07C 201/12 (20130101)
C07C 205/06 (20130101)
C07C 209/68 (20130101)
C07C 209/68 (20130101)
C07C 211/50 (20130101)
C07C 253/30 (20130101)
C07C 253/30 (20130101)
C07C 255/51 (20130101)
C07C 2523/72 (20130101)
C07C 2531/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045392 Unkefer et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico);  New Mexico Highlands University (Las Vegas, New Mexico)
INVENTOR(S) Pat J. Unkefer (Los Alamos, New Mexico);  Rodolfo A. Martinez (Santa Fe, New Mexico);  David R. Glass (Las Vegas, New Mexico)
ABSTRACT A process for synthesizing 4-amino-2,4-dioxobutanoic acid involves reacting diethyl oxalate with sodium ethoxide in ethanol to form a reaction mixture, and afterward adding ethyl cyanoacetate to the reaction mixture and allowing a reaction to proceed under conditions suitable to form a first reaction product of the formula diethyl-2-cyano-3-hydroxy-butenedioate, and then isolating the diethyl-2-cyano-3-hydroxybutenedioate, and afterward reacting the diethyl-2-cyano-3-hydroxy-butenedioate with aqueous sodium hydroxide under conditions suitable to form 4-amino-2,4-dioxobutanoic acid.
FILED Thursday, March 14, 2013
APPL NO 13/828905
ART UNIT 1672 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 231/06 (20130101)
C07C 231/06 (20130101)
C07C 235/80 (20130101)
C07C 253/30 (20130101) Original (OR) Class
C07C 253/30 (20130101)
C07C 255/23 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045549 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Huanzhong Wang (Storrs, Connecticut);  Fang Chen (Ardmore, Oklahoma);  Richard A. Dixon (Ardmore, Oklahoma)
ASSIGNEE(S) The Samuel Roberts Noble Foundation, Inc. (Ardmore, Oklahoma)
INVENTOR(S) Huanzhong Wang (Storrs, Connecticut);  Fang Chen (Ardmore, Oklahoma);  Richard A. Dixon (Ardmore, Oklahoma)
ABSTRACT The invention provides methods for modifying lignin, cellulose, xylan, and hemicellulose content in plants, and for achieving ectopic lignification and, for instance, secondary cell wall synthesis in pith cells, by altered regulation of a WRKY transcription factor. Nucleic acid constructs for altered WRKY-TF expression are described. Transgenic plants are provided that comprise modified pith cell walls, and lignin, cellulose, and hemicellulose content. Plants described herein may be used, for example, as improved biofuel feedstock and as highly digestible forage crops.
FILED Thursday, November 03, 2011
APPL NO 13/288677
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8245 (20130101)
C12N 15/8246 (20130101)
C12N 15/8255 (20130101)
C12N 15/8261 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045579 Xia et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Yan Xia (Mountain View, California);  Benjamin R Sveinbjornsson (Pasadena, California);  Robert H Grubbs (South Pasadena, California);  Raymond Weitekamp (Pasadena, California);  Garret M Miyake (Pasadena, California);  Victoria Piunova (Altadena, California);  Christopher Scot Daeffler (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Yan Xia (Mountain View, California);  Benjamin R Sveinbjornsson (Pasadena, California);  Robert H Grubbs (South Pasadena, California);  Raymond Weitekamp (Pasadena, California);  Garret M Miyake (Pasadena, California);  Victoria Piunova (Altadena, California);  Christopher Scot Daeffler (Pasadena, California)
ABSTRACT The invention provides a class of wedge-type block copolymers having a plurality of chemically different blocks, at least a portion of which incorporates a wedge group-containing block providing useful properties. For example, use of one or more wedge group-containing blocks in some block copolymers of the invention significantly inhibits chain entanglement and, thus, the present block copolymers materials provide a class of polymer materials capable of efficient molecular self-assembly to generate a range of structures, such as periodic nanostructures and microstructures. Materials of the present invention include copolymers having one or more wedge group-containing blocks, and optionally for some applications copolymers also incorporating one or more polymer side group-containing blocks. The present invention also provides useful methods of making and using wedge-type block copolymers.
FILED Wednesday, March 13, 2013
APPL NO 13/801710
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 2201/0149 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 222/04 (20130101)
C08F 222/40 (20130101)
C08F 232/08 (20130101)
C08F 293/00 (20130101)
C08F 299/00 (20130101) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/08 (20130101)
C08G 81/00 (20130101)
C08G 2261/74 (20130101)
C08G 2261/126 (20130101)
C08G 2261/128 (20130101)
C08G 2261/146 (20130101)
C08G 2261/149 (20130101)
C08G 2261/418 (20130101)
C08G 2261/1426 (20130101)
C08G 2261/3324 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045698 Lupton et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Property Assessed Clean Energy Program (PACE)
APPLICANT(S) UOP LLC (Des Plaines, Illinois)
ASSIGNEE(S) UOP LLC (Des Plaines, Illinois)
INVENTOR(S) Francis Stephen Lupton (Evanston, Illinois);  Praneeth Edirisinghe (Chicago, Illinois)
ABSTRACT Methods for processing algal oils are provided. In an embodiment, a method for removing a contaminant from an oil includes contacting the oil with a base to form an intermediate solution. Further, the method includes contacting the intermediate solution with an acid to form an acidic solution. The method separates the acidic solution into an oil portion and an aqueous waste portion including the contaminant.
FILED Friday, June 28, 2013
APPL NO 13/931636
ART UNIT 1672 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 1/002 (20130101) Original (OR) Class

Producing, e.g by Pressing Raw Materials or by Extraction From Waste Materials, Refining or Preserving Fats, Fatty Substances, e.g Lanolin, Fatty Oils or Waxes; Essential Oils; Perfumes
C11B 3/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045699 Brecher et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Charles G. Mones (Cheyenne, Wyoming);  Frank D. Guffey (Laramie, Wyoming);  Phyllis J. Brecher (Laramie, Wyoming)
ASSIGNEE(S) The University of Wyoming Research Corporation (Laramie, Wyoming)
INVENTOR(S) Lee E. Brecher (Laramie, Wyoming);  Charles G. Mones (Cheyenne, Wyoming);  Frank D. Guffey (Laramie, Wyoming)
ABSTRACT A hydrocarbonaceous material upgrading method may involve a novel combination of heating, vaporizing and chemically reacting hydrocarbonaceous feedstock that is substantially unpumpable at pipeline conditions, and condensation of vapors yielded thereby, in order to upgrade that feedstock to a hydrocarbonaceous material condensate that meets crude oil pipeline specification.
FILED Monday, June 06, 2011
APPL NO 13/154277
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 9/007 (20130101) Original (OR) Class
C10G 51/023 (20130101)
C10G 2300/302 (20130101)
C10G 2300/308 (20130101)
C10G 2300/1025 (20130101)
C10G 2300/1033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045710 Green et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Peter F. Green (Ann Arbor, Michigan);  Ernest C. McIntyre (Ypsilanti, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Peter F. Green (Ann Arbor, Michigan);  Ernest C. McIntyre (Ypsilanti, Michigan)
ABSTRACT Electrorheological fluids and methods include changes in liquid-like materials that can flow like milk and subsequently form solid-like structures under applied electric fields; e.g., about 1 kV/mm. Such fluids can be used in various ways as smart suspensions, including uses in automotive, defense, and civil engineering applications. Electrorheological fluids and methods include one or more polar molecule substituted polyhedral silsesquioxanes (e.g., sulfonated polyhedral silsesquioxanes) and one or more oils (e.g., silicone oil), where the fluid can be subjected to an electric field.
FILED Friday, April 06, 2012
APPL NO 13/441734
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 139/00 (20130101) Original (OR) Class
C10M 171/001 (20130101)
C10M 2203/1006 (20130101)
C10M 2203/1025 (20130101)
C10M 2205/04 (20130101)
C10M 2229/04 (20130101)
C10M 2229/025 (20130101)
C10M 2229/041 (20130101)
C10M 2229/053 (20130101)
C10M 2229/0415 (20130101)
C10M 2229/0535 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2230/60 (20130101)
C10N 2250/12 (20130101)
C10N 2260/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045741 Thompson et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) David N. Thompson (Idaho Falls, Idaho);  William A. Apel (Jackson, Wyoming);  Vicki S. Thompson (Idaho Falls, Idaho);  David W. Reed (Idaho Falls, Idaho);  Jeffrey A. Lacey (Idaho Falls, Idaho);  Emily D. Henriksen (Idaho Falls, Idaho)
ABSTRACT Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.
FILED Friday, June 28, 2013
APPL NO 13/930517
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)
C12N 9/18 (20130101) Original (OR) Class
C12N 9/88 (20130101)
C12N 9/248 (20130101)
C12N 9/1051 (20130101)
C12N 9/2402 (20130101)
C12N 9/2408 (20130101)
C12N 9/2434 (20130101)
C12N 9/2437 (20130101)
C12N 9/2445 (20130101)
C12N 9/2465 (20130101)
C12N 9/2471 (20130101)
C12N 9/2494 (20130101)
C12N 15/52 (20130101)

Enzymes
C12Y 204/0102 (20130101)
C12Y 301/01001 (20130101)
C12Y 301/01073 (20130101)
C12Y 301/02004 (20130101)
C12Y 302/0102 (20130101)
C12Y 302/01008 (20130101)
C12Y 302/01015 (20130101)
C12Y 302/01021 (20130101)
C12Y 302/01022 (20130101)
C12Y 302/01037 (20130101)
C12Y 302/01055 (20130101)
C12Y 302/01078 (20130101)
C12Y 302/01091 (20130101)
C12Y 302/01131 (20130101)
C12Y 302/01133 (20130101)
C12Y 402/01008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045748 Teter et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Sarah Teter (Menlo Park, California);  Michael Lamsa (Davis, California);  Joel Cherry (Davis, California);  Connie Ward (Hamilton, Montana)
ASSIGNEE(S) Novozymes, Inc. (Davis, California)
INVENTOR(S) Sarah Teter (Menlo Park, California);  Michael Lamsa (Davis, California);  Joel Cherry (Davis, California);  Connie Ward (Hamilton, Montana)
ABSTRACT The present invention relates to methods for expression screening of filamentous fungal transformants, comprising: (a) isolating single colony transformants of a DNA library introduced into E. coli; (b) preparing DNA from each of the single colony E. coli transformants; (c) introducing a sample of each of the DNA preparations of step (b) into separate suspensions of protoplasts of a filamentous fungus to obtain transformants thereof, wherein each transformant contains one or more copies of an individual polynucleotide from the DNA library; (d) growing the individual filamentous fungal transformants of step (c) on selective growth medium, thereby permitting growth of the filamentous fungal transformants, while suppressing growth of untransformed filamentous fungi; and (e) measuring activity or a property of each polypeptide encoded by the individual polynucleotides. The present invention also relates to isolated polynucleotides encoding polypeptides of interest obtained by such methods, to nucleic acid constructs, expression vectors, and recombinant host cells comprising the isolated polynucleotides, and to methods of producing the polypeptides encoded by the isolated polynucleotides.
FILED Thursday, May 26, 2005
APPL NO 11/140150
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/80 (20130101)
C12N 15/1037 (20130101) Original (OR) Class
C12N 15/1086 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 40/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045764 Tien et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Ming Tien (State College, Pennsylvania);  John Carlson (Port Matilda, Pennsylvania);  Haiying Liang (Clemson, South Carolina)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Ming Tien (State College, Pennsylvania);  John Carlson (Port Matilda, Pennsylvania);  Haiying Liang (Clemson, South Carolina)
ABSTRACT Transgenic lignocellulosic plants are provided according to embodiments of the present invention, the transgenic plants transformed with an expression cassette encoding a protein operably linked to a signal peptide which targets the protein to a cell wall of the transgenic plant, where at least 5% of the total amino acid residues of the protein are tyrosine, lysine, serine, threonine or cysteine. Methods of increasing lignin-protein bonds in a lignocellulosic plant are provided according to embodiments of the present invention which include expressing a recombinant nucleic acid in a lignocellulosic plant, the recombinant nucleic acid encoding a protein operably linked to a signal peptide which targets the protein to the cell wall of a plant, where at least 5% of the total amino acid residues of the protein are tyrosine, lysine, serine, threonine or cysteine.
FILED Friday, March 30, 2012
APPL NO 13/435761
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8246 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/10 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045804 Dumesic et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) James A. Dumesic (Verona, Wisconsin);  Jeremy S. Luterbacher (Madison, Wisconsin)
ABSTRACT A process to produce an aqueous solution of carbohydrates that contains C6-sugar-containing oligomers, C6 sugar monomers, C5-sugar-containing oligomers, C5 sugar monomers, or any combination thereof is presented. The process includes the steps of reacting biomass or a biomass-derived reactant with a solvent system including a lactone and water, and an acid catalyst. The reaction yields a product mixture containing water-soluble C6-sugar-containing oligomers, C6-sugar monomers, C5-sugar-containing oligomers, C5-sugar monomers, or any combination thereof. A solute is added to the product mixture to cause partitioning of the product mixture into an aqueous layer containing the carbohydrates and a substantially immiscible organic layer containing the lactone.
FILED Tuesday, January 08, 2013
APPL NO 13/736550
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides
C13K 1/02 (20130101) Original (OR) Class
C13K 1/06 (20130101)
C13K 13/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045839 Zappi et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Guillermo Daniel Zappi (Nisakayuna, New York);  Kenneth Paul Zarnoch (Scotia, New York);  Christian Andrew Huntley (Charlton, New York);  Dana Ray Swalla (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Guillermo Daniel Zappi (Nisakayuna, New York);  Kenneth Paul Zarnoch (Scotia, New York);  Christian Andrew Huntley (Charlton, New York);  Dana Ray Swalla (Schenectady, New York)
ABSTRACT The present techniques provide electrochemical devices having enhanced electrodes with surfaces that facilitate operation, such as by formation of a porous nickel layer on an operative surface, particularly of the cathode. The porous metal layer increases the surface area of the electrode, which may result in increasing the efficiency of the electrochemical devices. The formation of the porous metal layer is performed in situ, that is, after the assembly of the electrodes into an electrochemical device. The in situ process offers a number of advantages, including the ability to protect the porous metal layer on the electrode surface from damage during assembly of the electrochemical device. The enhanced electrode and the method for its processing may be used in any number of electrochemical devices, and is particularly well suited for electrodes in an electrolyzer useful for splitting water into hydrogen and oxygen.
FILED Tuesday, June 10, 2008
APPL NO 12/136331
ART UNIT 1754 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/10 (20130101)
C25B 9/206 (20130101)
C25B 11/00 (20130101)
C25B 15/00 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/562 (20130101)
C25D 5/08 (20130101)
C25D 5/48 (20130101) Original (OR) Class
C25D 17/00 (20130101)
C25D 17/002 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046051 Narayanaswamy et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Kushal Narayanaswamy (Sterling Heights, Michigan);  Calvin K. Koch (Bloomfield Hills, Michigan);  Paul M. Najt (Bloomfield Hills, Michigan);  Gerald A. Szekely, Jr. (Sterling Heights, Michigan);  Joel G. Toner (Bad Axe, Michigan)
ASSIGNEE(S) GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
INVENTOR(S) Kushal Narayanaswamy (Sterling Heights, Michigan);  Calvin K. Koch (Bloomfield Hills, Michigan);  Paul M. Najt (Bloomfield Hills, Michigan);  Gerald A. Szekely, Jr. (Sterling Heights, Michigan);  Joel G. Toner (Bad Axe, Michigan)
ABSTRACT A spark-ignition, direct-injection internal combustion engine is coupled to an exhaust aftertreatment system including a three-way catalytic converter upstream of an NH3-SCR catalyst. A method for operating the engine includes operating the engine in a fuel cutoff mode and coincidentally executing a second fuel injection control scheme upon detecting an engine load that permits operation in the fuel cutoff mode.
FILED Thursday, June 09, 2011
APPL NO 13/156655
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines
F01N 3/101 (20130101)
F01N 3/2066 (20130101)
F01N 13/009 (20130101)
F01N 2900/1622 (20130101)

Controlling Combustion Engines
F02D 41/024 (20130101)
F02D 41/123 (20130101) Original (OR) Class
F02D 41/126 (20130101)
F02D 41/402 (20130101)
F02D 41/3029 (20130101)
F02D 41/3076 (20130101)
F02D 2200/0802 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/22 (20130101)
Y02T 10/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046268 Condit et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance (Idaho Falls, Idaho)
INVENTOR(S) Reston A. Condit (Idaho Falls, Idaho);  Michael A. Daniels (Idaho Falls, Idaho);  Gregory P. Clemens (Idaho Falls, Idaho);  Eric S. Tomberlin (Idaho Falls, Idaho);  Joel A. Johnson (Rigby, Idaho)
ABSTRACT A timer key relating to monitoring a countdown time of a countdown routine of an electronic device is disclosed. The timer key comprises a processor configured to respond to a countdown time associated with operation of the electronic device, a display operably coupled with the processor, and a housing configured to house at least the processor. The housing has an associated structure configured to engage with the electronic device to share the countdown time between the electronic device and the timer key. The processor is configured to begin a countdown routine based at least in part on the countdown time, wherein the countdown routine is at least substantially synchronized with a countdown routine of the electronic device when the timer key is removed from the electronic device. A system and method for synchronizing countdown routines of a timer key and an electronic device are also disclosed.
FILED Monday, April 14, 2014
APPL NO 14/252531
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ignition; Extinguishing-devices
F23Q 21/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046463 Adler et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Stuart B. Adler (Seattle, Washington);  Jamie R. Wilson (Seattle, Washington);  Shawn L. Huff (Seattle, Washington);  Daniel T. Schwartz (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Stuart B. Adler (Seattle, Washington);  Jamie R. Wilson (Seattle, Washington);  Shawn L. Huff (Seattle, Washington);  Daniel T. Schwartz (Seattle, Washington)
ABSTRACT A method for conducting nonlinear electrochemical impedance spectroscopy. The method includes quantifying the nonlinear response of an electrochemical system by measuring higher-order current or voltage harmonics generated by moderate-amplitude sinusoidal current or voltage perturbations. The method involves acquisition of the response signal followed by time apodization and fast Fourier transformation of the data into the frequency domain, where the magnitude and phase of each harmonic signal can be readily quantified. The method can be implemented on a computer as a software program.
FILED Friday, April 21, 2006
APPL NO 11/408594
ART UNIT 1759 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/02 (20130101) Original (OR) Class
G01N 27/021 (20130101)
G01N 27/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046612 Wang et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Zhehui Wang (Los Alamos, New Mexico);  Christopher L. Morris (Los Alamos, New Mexico);  Jeffrey D. Bacon (Santa Fe, New Mexico)
ABSTRACT A double-helix Boron-10 powder detector having intrinsic thermal neutron detection efficiency comparable to 36″ long, 2-in diameter, 2-bar Helium-3 detectors, and which can be used to replace such detectors for use in portal monitoring, is described. An embodiment of the detector includes a metallic plate coated with Boron-10 powder for generating alpha and Lithium-7 particles responsive to neutrons impinging thereon supported by insulators affixed to at least two opposing edges; a grounded first wire wound in a helical manner around two opposing insulators; and a second wire having a smaller diameter than that of the first wire, wound in a helical manner around the same insulators and spaced apart from the first wire, the second wire being positively biased. A gas, disposed within a gas-tight container enclosing the plate, insulators and wires, and capable of stopping alpha and Lithium-7 particles and generating electrons produces a signal on the second wire which is detected and subsequently related to the number of neutrons impinging on the plate.
FILED Tuesday, March 12, 2013
APPL NO 13/796597
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 3/008 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046619 Blackburn et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Brandon W. Blackburn (Idaho Falls, Idaho);  David L. Chichester (Idaho Falls, Idaho);  Scott M. Watson (Idaho Falls, Idaho);  James T. Johnson (Rigby, Idaho);  Mathew T. Kinlaw (Idaho Falls, Idaho)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts);  U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Brandon W. Blackburn (Idaho Falls, Idaho);  David L. Chichester (Idaho Falls, Idaho);  Scott M. Watson (Idaho Falls, Idaho);  James T. Johnson (Rigby, Idaho);  Mathew T. Kinlaw (Idaho Falls, Idaho)
ABSTRACT Methods and apparatus to capture images of fluorescence generated by ionizing radiation and determine a position of a beam of ionizing radiation generating the fluorescence from the captured images. In one embodiment, the fluorescence is the result of ionization and recombination of nitrogen in air.
FILED Thursday, December 15, 2011
APPL NO 13/326970
ART UNIT 2884 — Optics
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 5/0016 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046620 Vu et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Cung Khac Vu (Houston, Texas);  Christopher Skelt (Houston, Texas);  Kurt Nihei (Oakland, California);  Paul A. Johnson (Santa Fe, New Mexico);  Robert Guyer (Reno, Nevada);  James A. Ten Cate (Los Alamos, New Mexico);  Pierre-Yves Le Bas (Los Alamos, New Mexico);  Carène S. Larmat (Los Alamos, New Mexico)
ASSIGNEE(S) LOS ALAMOS NATIONAL SECURITY LLC (Los Alamos, New Mexico);  CHEVRON U.S.A. INC. (San Ramon, California)
INVENTOR(S) Cung Khac Vu (Houston, Texas);  Christopher Skelt (Houston, Texas);  Kurt Nihei (Oakland, California);  Paul A. Johnson (Santa Fe, New Mexico);  Robert Guyer (Reno, Nevada);  James A. Ten Cate (Los Alamos, New Mexico);  Pierre-Yves Le Bas (Los Alamos, New Mexico);  Carène S. Larmat (Los Alamos, New Mexico)
ABSTRACT A system and a method for generating a three-dimensional image of a rock formation, compressional velocity VP, shear velocity VS and velocity ratio VP/VS of a rock formation are provided. A first acoustic signal includes a first plurality of pulses. A second acoustic signal from a second source includes a second plurality of pulses. A detected signal returning to the borehole includes a signal generated by a non-linear mixing process from the first and second acoustic signals in a non-linear mixing zone within an intersection volume. The received signal is processed to extract the signal over noise and/or signals resulting from linear interaction and the three dimensional image of is generated.
FILED Wednesday, November 09, 2011
APPL NO 13/292929
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/006 (20130101) Original (OR) Class
G01V 1/44 (20130101)
G01V 1/46 (20130101)
G01V 1/50 (20130101)
G01V 1/52 (20130101)
G01V 2210/125 (20130101)
G01V 2210/127 (20130101)
G01V 2210/588 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 15/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046647 Bravo-Abad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Jorge Bravo-Abad (Madrid, Spain);  John D. Joannopoulos (Belmont, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jorge Bravo-Abad (Madrid, Spain);  John D. Joannopoulos (Belmont, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT The dielectric, three-dimensional photonic materials disclosed herein feature Dirac-like dispersion in quasi-two-dimensional systems. Embodiments include a face-centered cubic (fcc) structure formed by alternating layers of dielectric rods and dielectric slabs patterned with holes on respective triangular lattices. This fcc structure also includes a defect layer, which may comprise either dielectric rods or a dielectric slab with patterned with holes. This defect layer introduces Dirac cone dispersion into the fcc structure's photonic band structure. Examples of these fcc structures enable enhancement of the spontaneous emission coupling efficiency (the β-factor) over large areas, contrary to the conventional wisdom that the β-factor degrades as the system's size increases. These results enable large-area, low-threshold lasers; single-photon sources; quantum information processing devices; and energy harvesting systems.
FILED Tuesday, February 19, 2013
APPL NO 13/769954
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101)
G02B 6/1225 (20130101) Original (OR) Class
G02B 2006/1213 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046650 Lin et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Pao Tai Lin (Brighton, Massachusetts);  Yan Cai (Stoughton, Massachusetts);  Anuradha Murthy Agarwal (Weston, Massachusetts);  Lionel C. Kimerling (Concord, Massachusetts)
ASSIGNEE(S) The Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Pao Tai Lin (Brighton, Massachusetts);  Yan Cai (Stoughton, Massachusetts);  Anuradha Murthy Agarwal (Weston, Massachusetts);  Lionel C. Kimerling (Concord, Massachusetts)
ABSTRACT A chip-scale, air-clad semiconductor pedestal waveguide can be used as a mid-infrared (mid-IR) sensor capable of in situ monitoring of organic solvents and other analytes. The sensor uses evanescent coupling from a silicon or germanium waveguide, which is highly transparent in the mid-IR portion of the electromagnetic spectrum, to probe the absorption spectrum of fluid surrounding the waveguide. Launching a mid-IR beam into the waveguide exposed to a particular analyte causes attenuation of the evanescent wave's spectral components due to absorption by carbon, oxygen, hydrogen, and/or nitrogen bonds in the surrounding fluid. Detecting these changes at the waveguide's output provides an indication of the type and concentration of one or more compounds in the surrounding fluid. If desired, the sensor may be integrated onto a silicon substrate with a mid-IR light source and a mid-IR detector to form a chip-based spectrometer.
FILED Monday, November 11, 2013
APPL NO 14/076655
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/35 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/122 (20130101)
G02B 6/136 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047150 Blocksome et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael A. Blocksome (Rochester, Minnesota);  Amith R. Mamidala (Yorktown Heights, New York)
ABSTRACT Fencing data transfers in a parallel active messaging interface (‘PAMI’) of a parallel computer, the PAMI including data communications endpoints, each endpoint including a specification of data communications parameters for a thread of execution on a compute node, including specifications of a client, a context, and a task; the compute nodes coupled for data communications through the PAMI and through data communications resources including at least one segment of shared random access memory; including initiating execution through the PAMI of an ordered sequence of active SEND instructions for SEND data transfers between two endpoints, effecting deterministic SEND data transfers through a segment of shared memory; and executing through the PAMI, with no FENCE accounting for SEND data transfers, an active FENCE instruction, the FENCE instruction completing execution only after completion of all SEND instructions initiated prior to execution of the FENCE instruction for SEND data transfers between the two endpoints.
FILED Thursday, November 15, 2012
APPL NO 13/677507
ART UNIT 2448 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 9/544 (20130101)
G06F 9/546 (20130101) Original (OR) Class
G06F 15/16 (20130101)
G06F 15/17331 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047192 Sridharan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
INVENTOR(S) Vilas Sridharan (Brookline, Massachusetts);  Sudhanva Gurumurthi (Watertown, Massachusetts)
ABSTRACT A system and method for optimizing redundant output verification, are provided. A hardware-based store fingerprint buffer receives multiple instances of output from multiple instances of computation. The store fingerprint buffer generates a signature from the content included in the multiple instances of output. When a barrier is reached, the store fingerprint buffer uses the signature to verify the content is error-free.
FILED Friday, December 21, 2012
APPL NO 13/724987
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/08 (20130101) Original (OR) Class
G06F 11/167 (20130101)
G06F 11/1004 (20130101)
G06F 17/30743 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047397 Temple et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
APPLICANT(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Brian A. Temple (Los Alamos, New Mexico);  Jerawan C. Armstrong (Los Alamos, New Mexico);  Kevin L. Buescher (White Rock, New Mexico);  Jeffrey A. Favorite (Los Alamos, New Mexico)
ABSTRACT Disclosed herein are representative embodiments of methods, apparatus, and systems for performing radiography analysis. For example, certain embodiments perform radiographic analysis using mixed variable computation techniques. One exemplary system comprises a radiation source, a two-dimensional detector for detecting radiation transmitted through a object between the radiation source and detector, and a computer. In this embodiment, the computer is configured to input the radiographic image data from the two-dimensional detector and to determine one or more materials that form the object by using an iterative analysis technique that selects the one or more materials from hierarchically arranged solution spaces of discrete material possibilities and selects the layer interfaces from the optimization of the continuous interface data.
FILED Friday, September 28, 2012
APPL NO 13/631607
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 19/345 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048004 Ren et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
APPLICANT(S) GMZ Energy, Inc. (Waltham, Massachusetts);  Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Zhifeng Ren (Newton, Massachusetts);  Xiao Yan (Chestnut Hill, Massachusetts);  Giri Joshi (Brighton, Massachusetts);  Shuo Chen (Newton, Massachusetts);  Gang Chen (Carlisle, Massachusetts);  Bed Poudel (Brighton, Massachusetts);  James Christopher Caylor (Melrose, Massachusetts)
ABSTRACT Thermoelectric materials and methods of making thermoelectric materials having a nanometer mean grain size less than 1 micron. The method includes combining and arc melting constituent elements of the thermoelectric material to form a liquid alloy of the thermoelectric material and casting the liquid alloy of the thermoelectric material to form a solid casting of the thermoelectric material. The method also includes ball milling the solid casting of the thermoelectric material into nanometer mean size particles and sintering the nanometer size particles to form the thermoelectric material having nanometer scale mean grain size.
FILED Wednesday, December 19, 2012
APPL NO 13/719966
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/02 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048012 Shah et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Kedar G. Shah (San Francisco, California);  Satinderpall S. Pannu (Pleasanton, California);  Terri L. Delima (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Kedar G. Shah (San Francisco, California);  Satinderpall S. Pannu (Pleasanton, California);  Terri L. Delima (Livermore, California)
ABSTRACT A method of fabricating electrical feedthroughs selectively removes substrate material from a first side of an electrically conductive substrate (e.g. a bio-compatible metal) to form an array of electrically conductive posts in a substrate cavity. An electrically insulating material (e.g. a bio-compatible sealing glass) is then flowed to fill the substrate cavity and surround each post, and solidified. The solidified insulating material is then exposed from an opposite second side of the substrate so that each post is electrically isolated from each other as well as the bulk substrate. In this manner a hermetic electrically conductive feedthrough construction is formed having an array of electrical feedthroughs extending between the first and second sides of the substrate from which it was formed.
FILED Wednesday, April 18, 2012
APPL NO 14/009332
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3754 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 13/06 (20130101) Original (OR) Class

Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 3/04 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 3/445 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048097 Warren et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Emily L. Warren (Pasadena, California);  Heather A. Audesirk (Los Angeles, California);  Nathan S. Lewis (La Canada Flintridge, California)
ABSTRACT The disclosure provides methods of manufacturing semiconductive structures using stamping and VLS techniques.
FILED Wednesday, August 21, 2013
APPL NO 13/972809
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0237 (20130101)
H01L 21/0259 (20130101) Original (OR) Class
H01L 21/02381 (20130101)
H01L 21/02532 (20130101)
H01L 21/02639 (20130101)
H01L 21/02642 (20130101)
H01L 21/02645 (20130101)
H01L 21/02653 (20130101)
H01L 21/02656 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048358 Reese et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Jason A. Reese (Auburn, Michigan);  James R. Keenihan (Midland, Michigan);  Ryan S. Gaston (Midland, Michigan);  Keith L. Kauffmann (Ypsilanti, Michigan);  Joseph A. Langmaid (Caro, Michigan);  Leonardo C. Lopez (Midland, Michigan);  Kevin D. Maak (Midland, Michigan);  Michael E. Mills (Midland, Michigan);  Narayan Ramesh (Midland, Michigan);  Samar R. Teli (Midland, Michigan)
ASSIGNEE(S) Dow Global Technologies LLC (Midland, Michigan)
INVENTOR(S) Jason A. Reese (Auburn, Michigan);  James R. Keenihan (Midland, Michigan);  Ryan S. Gaston (Midland, Michigan);  Keith L. Kauffmann (Ypsilanti, Michigan);  Joseph A. Langmaid (Caro, Michigan);  Leonardo C. Lopez (Midland, Michigan);  Kevin D. Maak (Midland, Michigan);  Michael E. Mills (Midland, Michigan);  Narayan Ramesh (Midland, Michigan);  Samar R. Teli (Midland, Michigan)
ABSTRACT The present invention is premised upon an improved photovoltaic device (“PV device”), more particularly to an improved photovoltaic device with a multilayered photovoltaic cell assembly and a body portion joined at an interface region and including an intermediate layer, at least one interconnecting structural member, relieving feature, unique component geometry, or any combination thereof.
FILED Monday, December 12, 2011
APPL NO 13/989275
ART UNIT 1758 — Optics
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/05 (20130101)
H01L 31/0424 (20130101) Original (OR) Class

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 20/25 (20141201)
H02S 40/36 (20141201)

Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications
Y02B 10/12 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048480 Kim et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Yu Seung Kim (Los Alamos, New Mexico);  Dae Sik Kim (Daejeon, South Korea)
ASSIGNEE(S) LOS ALAMOS NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Yu Seung Kim (Los Alamos, New Mexico);  Dae Sik Kim (Daejeon, South Korea)
ABSTRACT Anion exchange polymer electrolytes that include guanidinium functionalized polymers may be used as membranes and binders for electrocatalysts in preparation of anodes for electrochemical cells such as solid alkaline fuel cells.
FILED Monday, August 13, 2012
APPL NO 13/584183
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 41/125 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/22 (20130101)
C08J 5/2262 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/36 (20130101)
H01M 4/623 (20130101)
H01M 8/083 (20130101)
H01M 8/1025 (20130101)
H01M 8/1039 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/521 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09049011 Agrawal
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) Washington State University Research Foundation (Pullman, Washington)
ASSIGNEE(S) Washington State University (Pullman, Washington)
INVENTOR(S) Punit Agrawal (Seattle, Washington)
ABSTRACT This disclosure describes a distributed, fault-tolerant security system that enables the secure storage and distribution of private keys. In one implementation, the security system includes a plurality of computing resources that independently store private keys provided by publishers and encrypted using a single security system public key. To protect against malicious activity, the security system private key necessary to decrypt the publication private keys is not stored at any of the computing resources. Rather portions, or shares of the security system private key are stored at each of the computing resources within the security system and multiple security systems must communicate and share partial decryptions in order to decrypt the stored private key.
FILED Wednesday, August 14, 2013
APPL NO 13/967029
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/085 (20130101) Original (OR) Class
H04L 9/0888 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE45539 Anderson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Brian L. Anderson (Lodi, California);  Bill W. Colston (San Ramon, California);  Christopher J. Elkin (San Ramon, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Brian L. Anderson (Lodi, California);  Bill W. Colston (San Ramon, California);  Christopher J. Elkin (San Ramon, California)
ABSTRACT A system for nucleic acid amplification of a sample comprises partitioning the sample into partitioned sections and performing PCR on the partitioned sections of the sample. Another embodiment of the invention provides a system for nucleic acid amplification and detection of a sample comprising partitioning the sample into partitioned sections, performing PCR on the partitioned sections of the sample, and detecting and analyzing the partitioned sections of the sample.
FILED Friday, March 30, 2012
APPL NO 13/436693
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6844 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 09044335 Bonassar et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Lawrence J. Bonassar (Ithaca, New York);  Roger Hartl (New York, New York);  Robert D. Bowles (Ithaca, New York);  Harry H. Gebhard (Tuebingen, Germany)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Lawrence J. Bonassar (Ithaca, New York);  Roger Hartl (New York, New York);  Robert D. Bowles (Ithaca, New York);  Harry H. Gebhard (Tuebingen, Germany)
ABSTRACT The present invention relates to a tissue-engineered intervertebral disc (IVD) suitable for total disc replacement in a mammal and methods of fabrication. The IVD comprises a nucleus pulposus structure comprising a first population of living cells that secrete a hydrophilic protein and an annulus fibrosis structure surrounding and in contact with the nucleus pulposus structure, the annulus fibrosis structure comprising a second population of living cells and type I collagen. The collagen fibrils in the annulus fibrosis structure are circumferentially aligned around the nucleus pulposus region due to cell-mediated contraction in the annulus fibrosis structure. Also disclosed are methods of fabricating tissue-engineered intervertebral discs.
FILED Wednesday, May 05, 2010
APPL NO 13/319025
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/442 (20130101) Original (OR) Class
A61F 2002/445 (20130101)
A61F 2002/4435 (20130101)
A61F 2002/4445 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/32 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/20 (20130101)
A61L 27/20 (20130101)
A61L 27/24 (20130101)
A61L 27/52 (20130101)
A61L 27/3817 (20130101)
A61L 27/3856 (20130101)
A61L 27/3886 (20130101)
A61L 2430/38 (20130101)

Compositions of Macromolecular Compounds
C08L 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044392 Gellman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
APPLICANT(S) Samuel H. Gellman (Madison, Wisconsin);  Shannon S. Stahl (Madison, Wisconsin);  Brendan P. Mowery (San Marcos, California);  Annelise Barron (Palo Alto, California);  Michelle Dohm (Palos Park, Illinois)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  Northwestern University (Evanston, Illinois)
INVENTOR(S) Samuel H. Gellman (Madison, Wisconsin);  Shannon S. Stahl (Madison, Wisconsin);  Brendan P. Mowery (San Marcos, California);  Annelise Barron (Palo Alto, California);  Michelle Dohm (Palos Park, Illinois)
ABSTRACT Non-natural oligomers have recently shown promise as functional analogues of lung surfactant proteins Band C (SP-B and SP-C), two helical and amphiphilic proteins that are clitical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restlicted to step-by-step, sequence-specific synthesis, which results in discrete oligomers that are intended to manifest specific structural attributes. Presented herein an alternative approach to SP-R mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. These materials, members of the nylon-3 family, arc prepared by ling-opening polymelization of 13-lactams. The best of the nylon-3 polymers display promising in vitro surfactant activities in a mixed lipid film. Pulsating bubble surfactometry data indicate that films containing the most surface-active polymers attain adsorptive and dynamic-cycling properties that surpass those of discrete peptides intended to mimic SP-B.
FILED Thursday, March 17, 2011
APPL NO 13/634576
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0082 (20130101) Original (OR) Class
A61K 47/32 (20130101)

Compositions of Macromolecular Compounds
C08L 77/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044515 Baldwin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Aaron Baldwin (Orange, California);  Kristi Lynn Kiick (Rising Sun, Maryland)
ASSIGNEE(S) UNIVERSITY OF DELAWARE (Newark, Delaware)
INVENTOR(S) Aaron Baldwin (Orange, California);  Kristi Lynn Kiick (Rising Sun, Maryland)
ABSTRACT The present invention is related to compositions which can undergo targeted degradation under certain physiological reducing conditions. The compositions may, for example, be hydrogels in which maleimide-functionalized low molecular weight heparin is cross-linked with various thiol-functionalized polyethylene glycol multi-arm star polymers. Both the gelation and degradation of the hydrogels can be modified by careful selection of the thiol. For example, hydrogels prepared from aryl thiol-maleimide adducts can undergo a retro Michael addition-type reaction, leading to degradation of the composition and release of the bioactive molecule.
FILED Thursday, September 06, 2012
APPL NO 13/605297
ART UNIT 1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/48215 (20130101) Original (OR) Class
A61K 47/48784 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044746 Podlaha-Murphy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Elizabeth J. Podlaha-Murphy (West Roxbury, Massachusetts);  Savidra Lucatero (Boston, Massachusetts)
ASSIGNEE(S) NORTHEASTERN UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Elizabeth J. Podlaha-Murphy (West Roxbury, Massachusetts);  Savidra Lucatero (Boston, Massachusetts)
ABSTRACT A Ti02-based photocatalyst is fabricated as a composite of titania with adhered nanostructures which contain a non-noble metal in galvanic contact with a noble metal. The catalyst effectively overcome aging and/or deactivation effects observed in a system free of the non-noble metal. The composite material showed a corrosion protective effect on the photoactivity of fresh catalyst for over 180-240 days, and it enhanced the rate of the water reduction reaction relative to bare Ti02. Variations in porosity and non-noble metal content of the alloy portion of the nanostructures influenced the performance of the catalyst composite. The protective effect of the non-noble metal is through a cathodic corrosion protection mechanism.
FILED Friday, September 16, 2011
APPL NO 13/824583
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/063 (20130101)
B01J 23/52 (20130101)
B01J 23/8906 (20130101)
B01J 23/8973 (20130101)
B01J 35/004 (20130101) Original (OR) Class
B01J 35/06 (20130101)
B01J 35/0013 (20130101)
B01J 35/1066 (20130101)
B01J 37/0221 (20130101)
B01J 37/342 (20130101)
B01J 37/348 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/003 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 14/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044808 Chien et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Chia-Ling Chien (Cockeysviile, Maryland);  Donglei Fan (San Jose, California);  Robert Charles Cammarata (Columbia, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Chia-Ling Chien (Cockeysviile, Maryland);  Donglei Fan (San Jose, California);  Robert Charles Cammarata (Columbia, Maryland)
ABSTRACT A method for assembling multi-component nano-structures that includes dispersing a plurality of nano-structures in a fluid medium, and applying an electric field having an alternating current (AC) component and a direct current (DC) component to the fluid medium containing the plurality of nano-structures. The electric field causes a first nano-structure from the plurality of nano-structures to move to a predetermined position and orientation relative to a second nano-structure of the plurality of nano-structures such that the first and second nano-structures assemble into a multi-component nano-structure.
FILED Wednesday, March 03, 2010
APPL NO 13/147744
ART UNIT 1759 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields
B03C 5/005 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0022 (20130101) Original (OR) Class
B22F 1/0025 (20130101)
B22F 1/0096 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045476 Bassler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Bonnie Bassler (Princeton, New Jersey);  Lee Swem (San Carlos, California)
ABSTRACT Methods are provided for identifying molecules that can be used to positively and negatively manipulate quorum-sensing-mediated communication to control bacterial behavior. Small-molecule antagonists that disrupt quorum-sensing-mediated activities are identified. Methods are provided for disrupting detection of acyl-homoserine lactone autoinducer in Gram-negative bacteria by contacting the bacteria with the antagonists. Methods of inhibiting quorum sensing-mediated activity in Gram-negative bacteria are provided wherein the activity is pathogenicity, bioluminescence, siderophore production, type III secretion, or metalloprotease production.
FILED Tuesday, September 17, 2013
APPL NO 14/028999
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 41/10 (20130101)
A01N 43/28 (20130101)
A01N 43/52 (20130101)
A01N 43/78 (20130101)
A01N 43/82 (20130101)
A01N 43/90 (20130101)
A01N 43/653 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)

Acyclic or Carbocyclic Compounds
C07C 317/24 (20130101)

Heterocyclic Compounds
C07D 235/28 (20130101)
C07D 249/12 (20130101)
C07D 277/42 (20130101)
C07D 285/14 (20130101)
C07D 327/04 (20130101)
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045549 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Huanzhong Wang (Storrs, Connecticut);  Fang Chen (Ardmore, Oklahoma);  Richard A. Dixon (Ardmore, Oklahoma)
ASSIGNEE(S) The Samuel Roberts Noble Foundation, Inc. (Ardmore, Oklahoma)
INVENTOR(S) Huanzhong Wang (Storrs, Connecticut);  Fang Chen (Ardmore, Oklahoma);  Richard A. Dixon (Ardmore, Oklahoma)
ABSTRACT The invention provides methods for modifying lignin, cellulose, xylan, and hemicellulose content in plants, and for achieving ectopic lignification and, for instance, secondary cell wall synthesis in pith cells, by altered regulation of a WRKY transcription factor. Nucleic acid constructs for altered WRKY-TF expression are described. Transgenic plants are provided that comprise modified pith cell walls, and lignin, cellulose, and hemicellulose content. Plants described herein may be used, for example, as improved biofuel feedstock and as highly digestible forage crops.
FILED Thursday, November 03, 2011
APPL NO 13/288677
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8245 (20130101)
C12N 15/8246 (20130101)
C12N 15/8255 (20130101)
C12N 15/8261 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045576 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Shaoyi Jiang (Redmond, Washington);  Shengfu Chen (Zhejiang, China PRC)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Shaoyi Jiang (Redmond, Washington);  Shengfu Chen (Zhejiang, China PRC)
ABSTRACT Nonfouling copolymers and hydrogels comprising positively charged repeating units or latent positively charged repeating units and negatively charged units or latent positively charged units.
FILED Monday, February 09, 2009
APPL NO 12/367744
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 39/20 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/26 (20130101) Original (OR) Class
C08F 220/34 (20130101)
C08F 222/1006 (20130101)

Compositions of Macromolecular Compounds
C08L 51/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045657 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Science Foundation (NSF)
APPLICANT(S) Jennifer A. Lewis (Urbana, Illinois);  Robert F. Shepherd (St. Paul, Minnesota);  Robert A. Barry, III (Beaverton, Oregon);  Sara T. Parker (Portland, Oregon);  Jennifer N. H. Shepherd (St. Paul, Minnesota);  Pierre Wiltzius (Santa Barbara, California);  Ralph G. Nuzzo (Champaign, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Jennifer A. Lewis (Urbana, Illinois);  Robert F. Shepherd (St. Paul, Minnesota);  Robert A. Barry, III (Beaverton, Oregon);  Sara T. Parker (Portland, Oregon);  Jennifer N. H. Shepherd (St. Paul, Minnesota);  Pierre Wiltzius (Santa Barbara, California);  Ralph G. Nuzzo (Champaign, Illinois)
ABSTRACT A viscoelastic ink for direct writing of hydrogel structures includes a long chain polymer and a photopolymerizable moiety, which may be a photopolymerizable monomer or a photopolymerizable group attached to the long chain polymer. The ink may also include a crosslinking agent, a photoinitiator, and water. The long chain polymer is present at a concentration greater than a critical overlap concentration c* of the long chain polymer in the ink.
FILED Tuesday, March 22, 2011
APPL NO 13/636542
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/16 (20130101)
A61L 27/16 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/52 (20130101)
A61L 27/56 (20130101)

Compositions of Macromolecular Compounds
C08L 5/08 (20130101)
C08L 33/10 (20130101)
C08L 33/10 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/10 (20130101)
C09D 11/16 (20130101) Original (OR) Class
C09D 11/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045933 Jain et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Kanti Jain (Urbana, Illinois);  Linus Jang (Delmar, New York)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Kanti Jain (Urbana, Illinois);  Linus Jang (Delmar, New York)
ABSTRACT Energy-efficient windows incorporating spectrally selective optical elements capable of providing desirable optical characteristics (transmission, reflection, refraction or diffraction) for different wavelengths are disclosed herein. More specifically, energy-efficient windows incorporating suitably designed diffraction gratings to optimize the efficiency of the utilization of different spectral components of the solar radiation are disclosed.
FILED Monday, June 06, 2011
APPL NO 13/153601
ART UNIT 2872 — Optics
CURRENT CPC
Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 9/24 (20130101) Original (OR) Class
E06B 2009/2417 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/4277 (20130101)
G02B 27/4294 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046373 Bandyopadhyay et al.
FUNDED BY
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Amrit Bandyopadhyay (Washington, District of Columbia);  Daniel Hakim (Silver Spring, Maryland);  Benjamin E. Funk (Hanover, Maryland);  Eric Asher Kohn (Washington, District of Columbia);  Carole A. Teolis (Glenn Dale, Maryland);  Gilmer L. Blankenship (Washington, District of Columbia)
ASSIGNEE(S) TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S) Amrit Bandyopadhyay (Washington, District of Columbia);  Daniel Hakim (Silver Spring, Maryland);  Benjamin E. Funk (Hanover, Maryland);  Eric Asher Kohn (Washington, District of Columbia);  Carole A. Teolis (Glenn Dale, Maryland);  Gilmer L. Blankenship (Washington, District of Columbia)
ABSTRACT A system and method for locating, tracking, and/or monitoring the status of personnel and/or assets (collectively “trackees”), both indoors and outdoors, is provided. Tracking data obtained from any number of sources utilizing any number of tracking methods may be provided as input to a mapping application. The mapping application generates position estimates for trackees using a suite of mapping tools to make corrections to the tracking data. The mapping application further uses information from building data, when available, to enhance position estimates. Indoor tracking methods including sensor fusion methods, map matching methods, and map building methods may be implemented compute a more accurate tracking estimate for trackees. Outdoor tracking methods may be implemented to enhance outdoor tracking data by combining tracking estimates such as inertial tracks with magnetic and/or compass data if and when available, and with GPS, if and when available.
FILED Friday, September 14, 2012
APPL NO 13/616350
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 17/38 (20130101)
G01C 21/16 (20130101)
G01C 21/165 (20130101) Original (OR) Class
G01C 21/206 (20130101)
G01C 21/3438 (20130101)
G01C 21/3626 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/0294 (20130101)
G01S 19/39 (20130101)
G01S 19/48 (20130101)
G01S 19/49 (20130101)

Wireless Communication Networks
H04W 4/028 (20130101)
H04W 4/043 (20130101)
H04W 64/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046462 Pate et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Brooks Hart Pate (Charlottesville, Virginia);  Kevin K. Lehmann (Crozet, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Brooks Hart Pate (Charlottesville, Virginia);  Kevin K. Lehmann (Crozet, Virginia)
ABSTRACT A pulse train comprising chirped pulses of electromagnetic energy can be used to excite a sample, such as for spectroscopic analysis. The respective chirped pulses can include a frequency sweep across a first specified bandwidth during a respective chirped pulse duration, the respective chirped pulse duration establishing a first frequency-domain comb peak separation. A width of a frequency-domain comb peak can be established at least in part by a total duration of the pulse train, and a bandwidth of the first frequency-domain comb can be determined at least in part by the first specified bandwidth of the frequency sweep of the respective chirped pulses.
FILED Friday, June 17, 2011
APPL NO 13/704483
ART UNIT 2886 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3586 (20130101)
G01N 22/00 (20130101) Original (OR) Class

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046463 Adler et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Stuart B. Adler (Seattle, Washington);  Jamie R. Wilson (Seattle, Washington);  Shawn L. Huff (Seattle, Washington);  Daniel T. Schwartz (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Stuart B. Adler (Seattle, Washington);  Jamie R. Wilson (Seattle, Washington);  Shawn L. Huff (Seattle, Washington);  Daniel T. Schwartz (Seattle, Washington)
ABSTRACT A method for conducting nonlinear electrochemical impedance spectroscopy. The method includes quantifying the nonlinear response of an electrochemical system by measuring higher-order current or voltage harmonics generated by moderate-amplitude sinusoidal current or voltage perturbations. The method involves acquisition of the response signal followed by time apodization and fast Fourier transformation of the data into the frequency domain, where the magnitude and phase of each harmonic signal can be readily quantified. The method can be implemented on a computer as a software program.
FILED Friday, April 21, 2006
APPL NO 11/408594
ART UNIT 1759 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/02 (20130101) Original (OR) Class
G01N 27/021 (20130101)
G01N 27/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046627 Ravela
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Srinivas Ravela (Belmont, Massachusetts)
ABSTRACT A method for generating a coalesced image includes receiving a plurality of fields for a geographical region. A set of forces is determined for each of the fields by multiplying a gradient of a respective one of the fields with a difference between the respective one of the fields and each of the other fields. A net influence for each field is determined by averaging each of the forces associated with the respective field. A spectral filter is applied to each net influence to generate a respective value of a mode of motion used to deform each field and then displace each field until each field coalesces with each other field.
FILED Wednesday, May 29, 2013
APPL NO 13/904058
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Meteorology
G01W 1/10 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 7/2066 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046647 Bravo-Abad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Jorge Bravo-Abad (Madrid, Spain);  John D. Joannopoulos (Belmont, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jorge Bravo-Abad (Madrid, Spain);  John D. Joannopoulos (Belmont, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT The dielectric, three-dimensional photonic materials disclosed herein feature Dirac-like dispersion in quasi-two-dimensional systems. Embodiments include a face-centered cubic (fcc) structure formed by alternating layers of dielectric rods and dielectric slabs patterned with holes on respective triangular lattices. This fcc structure also includes a defect layer, which may comprise either dielectric rods or a dielectric slab with patterned with holes. This defect layer introduces Dirac cone dispersion into the fcc structure's photonic band structure. Examples of these fcc structures enable enhancement of the spontaneous emission coupling efficiency (the β-factor) over large areas, contrary to the conventional wisdom that the β-factor degrades as the system's size increases. These results enable large-area, low-threshold lasers; single-photon sources; quantum information processing devices; and energy harvesting systems.
FILED Tuesday, February 19, 2013
APPL NO 13/769954
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101)
G02B 6/1225 (20130101) Original (OR) Class
G02B 2006/1213 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047628 Mislove et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Alan Mislove (West Roxbury, Massachusetts);  Arash M Kakhki (Jamaica Plain, Massachusetts)
ABSTRACT Systems and methods are described for determining a weighted rating and a relative rating. In some embodiments, a receiving module and rating module are configured to receive an identity of a collector, a list of raters, and a social graph, determine for at least one rater a set of non-intersecting paths between the rater and the collector, calculate capacity values for non-intersecting paths, normalize path values, convert path values to a user weight, and apply the at least one rater's weight to the at least one rater's rating. In some embodiments, a receiving module and rating module are also configured to receive a rating for each of the items rated by the rater, calculate a transformed rating, calculate a relative rating, and assign a relative rating to an item.
FILED Thursday, March 13, 2014
APPL NO 14/210214
ART UNIT 3629 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/0282 (20130101) Original (OR) Class
G06Q 50/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048375 Law et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Matthew Law (Irvine, California);  Amanda S. Weber (Irvine, California);  Sean Seefeld (Irvine, California);  James Puthussery (Tustin, California)
ABSTRACT Systems and methods are provided for fabricating pyrite thin films from molecular inks. A process is provided that comprises dissolving simple iron-bearing and sulfur-bearing molecules in an appropriate solvent and then depositing the solution onto an appropriate substrate using one of several methods (roll-to-roll coating, spraying, spin coating, etc.), resulting in a solid film consisting of the molecules. These molecular precursor films are then heated to 200-600° C. in the presence of sulfur-bearing gases (e.g., S2, H2S) to convert the molecular films into films of crystalline iron pyrite (FeS2).
FILED Wednesday, March 13, 2013
APPL NO 13/799448
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/02 (20130101)
B05D 1/005 (20130101)
B05D 3/0254 (20130101)
B05D 3/0453 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/1864 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048419 Xu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Yong Xu (Troy, Michigan);  Zhuo Wang (Urbana, Illinois);  Qinglong Zheng (Detroit, Michigan)
ASSIGNEE(S) WAYNE STATE UNIVERSITY (Detroit, Michigan)
INVENTOR(S) Yong Xu (Troy, Michigan);  Zhuo Wang (Urbana, Illinois);  Qinglong Zheng (Detroit, Michigan)
ABSTRACT An arrangement that converts mechanical energy into electrical energy employs a base member and a cantilever member coupled thereto. The cantilever member has two piezoelectric layers with an air space therebetween. A proof mass is coupled to the cantilever member distal from the base member. The first and second piezoelectric layers are formed of lead zirconate titanate (PZT), and the output voltage of the cantilever member is proportional to the height of the air gap. A piezoresistive accelerometer that is useful for measuring mechanical vibration has a suspension beam and a piezoresistive layer be separated from the suspension beam. A method of monitoring an acoustic vibration utilizes a piezoresistive element having an air-spaced cantilever formed of a piezoelectric material in the vicinity of the system to be monitored and obtains an alternating voltage form the air-spaced cantilever of the piezoresistive element.
FILED Monday, June 02, 2008
APPL NO 12/451811
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/09 (20130101)
G01P 15/123 (20130101)
G01P 15/0922 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/1136 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 2/188 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048625 Zhou et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Heng Zhou (New York, New York);  Shu-Wei Huang (New York, New York);  Chee Wei Wong (Weehawken, New Jersey)
ABSTRACT Normal group velocity dispersion mode-locked optical frequency combs are provided on-chip. On-chip coherent frequency comb generation includes pulses showing temporal durations of about 74 fs. Pump detuning and bandpass filtering are provided for stabilizing and shaping the pulses from normal group velocity dispersion microresonators.
FILED Tuesday, July 29, 2014
APPL NO 14/445959
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/1106 (20130101) Original (OR) Class
H01S 3/08013 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048632 Dantus et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Marcos Dantus (Okemos, Michigan);  Bai Nie (Lansing, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S) Marcos Dantus (Okemos, Michigan);  Bai Nie (Lansing, Michigan)
ABSTRACT A laser apparatus includes a fiber oscillator. In another aspect, an Ytterbium (Yb) doped fiber is employed. Another aspect provides an unamplified laser pulse emitted from an Yb fiber oscillator having a repetition rate less than 5 MHz and a pulse energy greater than 100 nJ. In still an additional aspect, a flexible Yb fiber has a length greater than 1 m which is capable of being looped with an outside loop diameter less than 150 mm. Another aspect provides for a fiber oscillator with passive optical fiber lengths of at least 10 meters, and more preferably more than 100 meters while having repetition rates less than 4 MHz.
FILED Friday, March 15, 2013
APPL NO 13/833529
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00009 (20130101)
A61B 2018/00577 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/1618 (20130101)
H01S 3/2308 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048658 Lu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Wei Lu (Ann Arbor, Michigan);  Sung Hyun Jo (Sunnyvale, California)
ABSTRACT A method of suppressing propagation of leakage current in an array of switching devices. The method includes providing a dielectric breakdown element integrally and serially connected to a switching element within each of the switching device. A read voltage (for example) is applied to a selected cell. The propagation of leakage current is suppressed by each of the dielectric breakdown element in unselected cells in the array. The read voltage is sufficient to cause breakdown in the selected cells but insufficient to cause breakdown in the serially connected, unselected cells in a specific embodiment. Methods to fabricate of such devices and to program, to erase and to read the device are provided.
FILED Wednesday, April 30, 2014
APPL NO 14/265845
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Static Stores
G11C 13/003 (20130101)
G11C 13/004 (20130101)
G11C 13/0007 (20130101)
G11C 13/0069 (20130101)
G11C 13/0097 (20130101)
G11C 2213/33 (20130101)
G11C 2213/76 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/2409 (20130101)
H01L 27/2463 (20130101)
H01L 45/04 (20130101)
H01L 45/08 (20130101)
H01L 45/085 (20130101)
H01L 45/141 (20130101)
H01L 45/146 (20130101)
H01L 45/1233 (20130101)

Emergency Protective Circuit Arrangements
H02H 9/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048807 Pereira Da Cunha et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Mauricio Pereira Da Cunha (Orono, Maine);  Bennet Meulendyk (Manchester, Maine)
ASSIGNEE(S) University of Maine System Board of Trustees (Bangor, Maine)
INVENTOR(S) Mauricio Pereira Da Cunha (Orono, Maine);  Bennet Meulendyk (Manchester, Maine)
ABSTRACT Surface acoustic wave resonators for use in high temperature applications including a piezoelectric substrate, at least one interdigital transducer supported by the piezoelectric substrate, and a grating reflector supported by the piezoelectric substrate, the grating reflector being fabricated of a heavy metal and comprising a plurality of electrodes, at least one electrode of the plurality of electrodes being electrically isolated from at least one other electrode. Methods of making surface acoustic wave resonators are also included.
FILED Thursday, March 17, 2011
APPL NO 13/050389
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Impedance Networks, e.g Resonant Circuits; Resonators
H03H 9/02834 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09049185 Papadopoulos et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) EMC Corporation (Hopkinton, Massachusetts)
ASSIGNEE(S) EMC Corporation (Hopkinton, Massachusetts)
INVENTOR(S) Dimitrios Papadopoulos (Brighton, Massachusetts);  Nikolaos Triandopoulos (Arlington, Massachusetts);  Ran Canetti (Brookline, Massachusetts)
ABSTRACT Methods and apparatus are provided for authenticated hierarchical set operations. A third party server processes a query q (possibly from a client) on outsourced data sets S1, . . . , Sn on behalf of a source of the data. The query q comprises a hierarchical set operation. Authenticated Set Operation techniques for flat set operations can be iteratively applied for hierarchical set operations. In addition, bilinear accumulators are extended to provide an extractable accumulation scheme comprising a primary bilinear accumulator and a secondary bilinear accumulator. In addition, a query q is parsed as a tree and for each tree node, a Union/Intersection argument is provided that is related to one or more accumulation values associated with the corresponding tree node. The client receives an answer to the query and a verification proof comprising, for example, subset witnesses, completeness witnesses, and/or accumulation values, but not necessarily intermediate results associated with the internal tree nodes of the query q.
FILED Thursday, March 14, 2013
APPL NO 13/829374
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 17/30 (20130101)
G06F 21/6227 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE45541 Adelson
FUNDED BY
National Science Foundation (NSF)
Directorate for Social, Behavioral and Economic Sciences (SBE)
Division of Behavioral and Cognitive Sciences (BCS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Edward Adelson (Winchester, Massachusetts)
ABSTRACT A tactile sensor includes a photosensing structure, a volume of elastomer capable of transmitting an image, and a reflective skin covering the volume of elastomer. The reflective skin is illuminated through the volume of elastomer by one or more light sources, and has particles that reflect light incident on the reflective skin from within the volume of elastomer. The reflective skin is geometrically altered in response to pressure applied by an entity touching the reflective skin, the geometrical alteration causing localized changes in the surface normal of the skin and associated localized changes in the amount of light reflected from the reflective skin in the direction of the photosensing structure. The photosensing structure receives a portion of the reflected light in the form of an image, the image indicating one or more features of the entity producing the pressure.
FILED Thursday, October 03, 2013
APPL NO 14/045668
ART UNIT 2482 — Recording and Compression
CURRENT CPC
Electric Digital Data Processing
G06F 3/042 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 09044566 Wickham et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Reaction Systems, LLC (Golden, Colorado)
ASSIGNEE(S) Reaction Systems, LLC (Golden, Colorado)
INVENTOR(S) David T. Wickham (Lafayette, Colorado);  Kevin J. Gleason (Lafayette, Colorado);  Scott W. Cowley (Lakewood, Colorado)
ABSTRACT There is disclosed a portable life support system with a component for removal of at least one selected gas. In an embodiment, the system includes a supported liquid membrane having a first side and a second side in opposition to one another, the first side configured for disposition toward an astronaut and the second side configured for disposition toward a vacuum atmosphere. The system further includes an ionic liquid disposed between the first side and the second side of the supported liquid membrane, the ionic liquid configured for removal of at least one selected gas from a region housing the astronaut adjacent the first side of the supported liquid membrane to the vacuum atmosphere adjacent the second side of the supported liquid membrane. Other embodiments are also disclosed.
FILED Monday, March 03, 2014
APPL NO 14/195615
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/22 (20130101) Original (OR) Class

Devices, Apparatus or Methods for Life-saving
A62B 19/00 (20130101)
A62B 19/02 (20130101)

Separation
B01D 53/00 (20130101)
B01D 53/228 (20130101)
B01D 2257/504 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 13/00 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 9/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 31/20 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 10/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044743 Schryer et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) David R. Schryer (Poquoson, Virginia);  Jeffrey D. Jordan (Williamsburg, Virginia);  Ates Akyurtlu (Yorktown, Virginia);  Jale Akyurtlu (Yorktown, Virginia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) David R. Schryer (Poquoson, Virginia);  Jeffrey D. Jordan (Williamsburg, Virginia);  Ates Akyurtlu (Yorktown, Virginia);  Jale Akyurtlu (Yorktown, Virginia)
ABSTRACT This invention relates generally to a platinized tin oxide-based catalyst. It relates particularly to an improved platinized tin oxide-based catalyst able to decompose nitric oxide to nitrogen and oxygen without the necessity of a reducing gas.
FILED Thursday, March 18, 2010
APPL NO 12/726403
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/9418 (20130101)
B01D 2255/1021 (20130101)
B01D 2255/2073 (20130101)
B01D 2255/2094 (20130101)
B01D 2255/20761 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/54 (20130101)
B01J 23/56 (20130101)
B01J 23/626 (20130101) Original (OR) Class
B01J 37/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09045219 Bandera et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Johnson Space Center (JSC)
APPLICANT(S) Pablo Bandera (Goodyear, Arizona);  Paul Buchele (Glendale, Arizona)
ASSIGNEE(S) HONEYWELL INTERNATIONAL, INC. (Morristown, New Jersey)
INVENTOR(S) Pablo Bandera (Goodyear, Arizona);  Paul Buchele (Glendale, Arizona)
ABSTRACT A user input device for a vehicular electrical system is provided. The user input device includes a handle sized and shaped to be gripped by a human hand and a gimbal assembly within the handle. The gimbal assembly includes a first gimbal component, a second gimbal component coupled to the first gimbal component such that the second gimbal component is rotatable relative to the first gimbal component about a first axis, and a third gimbal component coupled to the second gimbal component such that the third gimbal component is rotatable relative to the second gimbal component about a second axis.
FILED Wednesday, June 18, 2008
APPL NO 12/141601
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 13/04 (20130101) Original (OR) Class

Control Devices or Systems Insofar as Characterised by Mechanical Features Only
G05G 9/047 (20130101)
G05G 9/04792 (20130101)
G05G 2009/04718 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046115 England et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) John Dwight England (Arab, Alabama);  Anthony R. Kelley (Somerville, Alabama)
ABSTRACT An eddy-current-minimizing flow plug has open flow channels formed between the plug's inlet and outlet. Each open flow channel includes (i) a first portion that originates at the inlet face and converges to a location within the plug that is downstream of the inlet, and (ii) a second portion that originates within the plug and diverges to the outlet. The diverging second portion is approximately twice the length of the converging first portion. The plug is devoid of planar surface regions at its inlet and outlet, and in fluid flow planes of the plug that are perpendicular to the given direction of a fluid flowing therethrough.
FILED Friday, November 09, 2012
APPL NO 13/673309
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 5/064 (20130101)
B01F 5/0613 (20130101)
B01F 5/0644 (20130101)

Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids
F15D 1/025 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046418 Choi et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Sang Hyouk Choi (Poquoson, Virginia);  Yeonjoon Park (Yorktown, Virginia)
ABSTRACT A spectrometer that includes a grating that disperses light via Fresnel diffraction according to wavelength onto a sensing area that coincides with an optical axis plane of the grating. The sensing area detects the dispersed light and measures the light intensity associated with each wavelength of the light. Because the spectrometer utilizes Fresnel diffraction, it can be miniaturized and packaged as an integrated circuit.
FILED Monday, February 25, 2013
APPL NO 13/775809
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/18 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 5/1842 (20130101)
G02B 5/1876 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046426 Okojie
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Robert S Okojie (Strongsville, Ohio)
ASSIGNEE(S) The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Robert S Okojie (Strongsville, Ohio)
ABSTRACT A modular apparatus for attaching sensors and electronics is disclosed. The modular apparatus includes a square recess including a plurality of cavities and a reference cavity such that a pressure sensor can be connected to the modular apparatus. The modular apparatus also includes at least one voltage input hole and at least one voltage output hole operably connected to each of the plurality of cavities such that voltage can be applied to the pressure sensor and received from the pressure sensor.
FILED Friday, June 15, 2012
APPL NO 13/524327
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 7/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047537 Hunt, Jr.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Prioria Robotics, Inc. (Gainesville, Florida)
ASSIGNEE(S) Prioria Robotics, Inc. (Gainesville, Florida)
INVENTOR(S) Walter Lee Hunt, Jr. (Gainesville, Florida)
ABSTRACT A detection process, contact recognition process, classification process, and identification process are applied to raw sensor data to produce an identified contact record set containing one or more identified contact records. A prioritization process is applied to the identified contact record set to assign a contact priority to each contact record in the identified contact record set. Data are removed from the contact records in the identified contact record set based on the contact priorities assigned to those contact records. A first contact stream is produced from the resulting contact records. The first contact stream is streamed in a contact transport stream. The contact transport stream may include and stream additional contact streams. The contact transport stream may be varied dynamically over time based on parameters such as available bandwidth, contact priority, presence/absence of contacts, system state, and configuration parameters.
FILED Friday, December 21, 2012
APPL NO 13/724557
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00771 (20130101)
G06K 9/6267 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048759 Xu et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Tian-Bing Xu (Hampton, Virginia);  Emilie J. Siochi (Newport News, Virginia);  Lei Zuo (Nesconset, New York);  Xiaoning Jiang (Cary, North Carolina);  Jin Ho Kang (Newport News, Virginia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Tian-Bing Xu (Hampton, Virginia);  Emilie J. Siochi (Newport News, Virginia);  Lei Zuo (Nesconset, New York);  Xiaoning Jiang (Cary, North Carolina);  Jin Ho Kang (Newport News, Virginia)
ABSTRACT Embodiments of the disclosure include an apparatus and methods for using a piezoelectric device, that includes an outer flextensional casing, a first cell and a last cell serially coupled to each other and coupled to the outer flextensional casing such that each cell having a flextensional cell structure and each cell receives an input force and provides an output force that is amplified based on the input force. The apparatus further includes a piezoelectric stack coupled to each cell such that the piezoelectric stack of each cell provides piezoelectric energy based on the output force for each cell. Further, the last cell receives an input force that is the output force from the first cell and the last cell provides an output apparatus force In addition, the piezoelectric energy harvested is based on the output apparatus force. Moreover, the apparatus provides displacement based on the output apparatus force.
FILED Thursday, November 10, 2011
APPL NO 13/293846
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electric Machines Not Otherwise Provided for
H02N 2/043 (20130101) Original (OR) Class
H02N 2/186 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 09045383 Qiao et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Virent, Inc. (Madison, Wisconsin)
ASSIGNEE(S) Virent, Inc. (Madison, Wisconsin)
INVENTOR(S) Ming Qiao (Pewaukee, Wisconsin);  Randy D. Cortright (Madison, Wisconsin);  John Kania (Madison, Wisconsin);  Elizabeth Woods (Middleton, Wisconsin)
ABSTRACT The present invention provides methods, reactor systems, and catalysts for converting in a continuous process biomass to less complex oxygenated compounds for use in downstream processes to produce biofuels and chemicals. The invention includes methods of converting the components of biomass, such as hemicellulose, cellulose and lignin, to water-soluble materials, including lignocellulosic derivatives, cellulosic derivatives, hemicellulosic derivatives, carbohydrates, starches, polysaccharides, disaccharides, monosaccharides, sugars, sugar alcohols, alditols, polyols, diols, alcohols, ketones, cyclic ethers, esters, carboxylic acids, aldehydes, and mixtures thereof, using hydrogen and a heterogeneous liquefaction catalyst.
FILED Thursday, December 19, 2013
APPL NO 14/133996
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/34 (20130101)
B01J 23/462 (20130101)
B01J 23/464 (20130101)
B01J 23/687 (20130101)
B01J 23/6527 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 63/00 (20130101) Original (OR) Class

Acyclic or Carbocyclic Compounds
C07C 29/132 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 1/06 (20130101)
C10G 1/065 (20130101)
C10G 3/42 (20130101)
C10G 3/47 (20130101)
C10G 2300/44 (20130101)
C10G 2300/805 (20130101)
C10G 2300/1011 (20130101)
C10G 2300/1014 (20130101)
C10G 2400/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09046731 Lezec et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) National Institute of Standards and Technology (Gaithersburg, Maryland)
ASSIGNEE(S) THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Washington, District of Columbia)
INVENTOR(S) Henri J. Lezec (Bethesda, Maryland);  Erich C. Walter (Silver Spring, Maryland);  Amit Agrawal (Syracuse, New York);  Albert Alec Talin (Gaithersburg, Maryland);  Ting Xu (Gaithersburg, Maryland)
ABSTRACT Various plasmonic structures in the form of electrochromic optical switches are described which exhibit relatively high optical switching contrast. The switches generally include a collection of nanoslits formed in a thin electrically conductive film. An electrochromic material is disposed on the conductive film and along the sidewalls of the nanoslit(s).
FILED Friday, February 01, 2013
APPL NO 13/756605
ART UNIT 2872 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/15 (20130101)
G02F 1/1533 (20130101) Original (OR) Class
G02F 2001/1515 (20130101)
G02F 2203/10 (20130101)

Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information
G09G 3/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048414 Gergel-Hackett et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Nadine Gergel-Hackett (Germantown, Maryland);  Behrang Hamadani (Gaithersburg, Maryland);  Curt A. Richter (Olney, Maryland);  David James Gundlach (Montgomery Village, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Washington, District of Columbia)
INVENTOR(S) Nadine Gergel-Hackett (Germantown, Maryland);  Behrang Hamadani (Gaithersburg, Maryland);  Curt A. Richter (Olney, Maryland);  David James Gundlach (Montgomery Village, Maryland)
ABSTRACT A method of processing a nonvolatile memory device includes forming a first electrode, depositing a layer of sol-gel solution on the first electrode, hydrolyzing the layer of sol-gel solution to form a layer of variable electric resistance material, and forming a second electrode on the layer of variable electric resistance material.
FILED Monday, December 22, 2008
APPL NO 12/341059
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/101 (20130101)
H01L 45/08 (20130101) Original (OR) Class
H01L 45/146 (20130101)
H01L 45/1233 (20130101)
H01L 45/1608 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 09046627 Ravela
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Srinivas Ravela (Belmont, Massachusetts)
ABSTRACT A method for generating a coalesced image includes receiving a plurality of fields for a geographical region. A set of forces is determined for each of the fields by multiplying a gradient of a respective one of the fields with a difference between the respective one of the fields and each of the other fields. A net influence for each field is determined by averaging each of the forces associated with the respective field. A spectral filter is applied to each net influence to generate a respective value of a mode of motion used to deform each field and then displace each field until each field coalesces with each other field.
FILED Wednesday, May 29, 2013
APPL NO 13/904058
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Meteorology
G01W 1/10 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 7/2066 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047013 Sae-Chim et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) Prapon Sae-Chim (Bellevue, Washington);  Thomas F. McGuffin (Bellevue, Washington);  Patrick Ludwig (Renton, Washington)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Prapon Sae-Chim (Bellevue, Washington);  Thomas F. McGuffin (Bellevue, Washington);  Patrick Ludwig (Renton, Washington)
ABSTRACT An avionics messaging system comprises a memory configured to store a plurality of pre-defined avionics message elements; a display unit configured to display data; a user input device configured to receive input from a user; and a processing unit configured to output a user-customizable list of pre-defined avionics message elements to the display unit, the user-customizable list comprising at least a subset of the plurality of pre-defined avionics message elements; wherein the processing unit is further configured to update the user-customizable list based on input received from the user input device; wherein the processing unit is further configured to provide a message composition screen to the display unit based on user input received from the user input device; and wherein the message composition screen corresponds to a pre-defined avionics message element selected from the user-customizable list of pre-defined avionics message elements.
FILED Wednesday, September 01, 2010
APPL NO 12/873591
ART UNIT 2171 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 3/0489 (20130101) Original (OR) Class
G06F 17/276 (20130101)

Traffic Control Systems
G08G 5/0013 (20130101)
G08G 5/0021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047384 Barbeau et al.
FUNDED BY
Department of Transportation (USDOT)
U.S. State Government
State of Florida
Florida Department of Transportation (FDOT)
APPLICANT(S) Sean J. Barbeau (Tampa, Florida);  Philip L. Winters (Tampa, Florida);  Rafael Perez (Temple Terrace, Florida);  Miguel Labrador (Tampa, Florida);  Nevine Georggi (Valrico, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Sean J. Barbeau (Tampa, Florida);  Philip L. Winters (Tampa, Florida);  Rafael Perez (Temple Terrace, Florida);  Miguel Labrador (Tampa, Florida);  Nevine Georggi (Valrico, Florida)
ABSTRACT Disclosed is an automated trip-purpose detection method that utilizes GPS Data collected by GPS-enabled devices. The GPS data is compared against a GIS map to obtain various spatial and location characteristics of the surrounding area. This information is then used to derive a traveler's trip purpose. In a preferred embodiment, the inventive method is implemented automatically without any needed manipulation of GIS data. Additionally, the method integrates location information as defined by the user for critical locations such as home and work. These personalized locations allow the method to immediately identify the two most common types of trips: work-related trips and trips returning home.
FILED Monday, January 14, 2008
APPL NO 12/013789
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Electric Digital Data Processing
G06F 17/3087 (20130101) Original (OR) Class
G06F 17/30241 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 1/10 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/18 (20130101)
H04L 67/22 (20130101)

Wireless Communication Networks
H04W 4/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 09044434 Guillemin et al.
FUNDED BY
U.S. State Government
State of Oregon
APPLICANT(S) Karen Guillemin (Eugene, Oregon);  Allison Banse (Eugene, Oregon)
ASSIGNEE(S) State of Oregon, Acting by and Through the State Board of Higher Education on behalf of University of Oregon (Eugene, Oregon)
INVENTOR(S) Karen Guillemin (Eugene, Oregon);  Allison Banse (Eugene, Oregon)
ABSTRACT Disclosed herein are methods of increasing epithelial cell proliferation (such as intestinal epithelial cell proliferation) by contacting epithelial cells with one or more CBPs. In some examples, the methods include administering the CBP to a subject, such as a subject in need of increased epithelial cell proliferation. Also disclosed herein are methods of identifying a subject having or at risk of developing hyperproliferation of epithelial cells (such as intestinal epithelial cells). Further disclosed are methods of decreasing epithelial cell proliferation by decreasing expression and/or activity of a CBP and methods of identifying inhibitors of epithelial cell proliferation and/or CBP activity.
FILED Tuesday, October 22, 2013
APPL NO 14/060392
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/164 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 33/57419 (20130101)
G01N 2333/195 (20130101)
G01N 2800/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044518 Pettit et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
U.S. State Government
State of Arizona
APPLICANT(S) George R. Pettit (Paradise Valley, Arizona);  Fiona Hogan (Gilbert, Arizona);  Steven Toms (Wellington, New Zealand)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) George R. Pettit (Paradise Valley, Arizona);  Fiona Hogan (Gilbert, Arizona);  Steven Toms (Wellington, New Zealand)
ABSTRACT The present invention relates to new auristatin compounds and prodrugs thereof, compositions comprising them and uses thereof.
FILED Thursday, March 29, 2012
APPL NO 14/007743
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/472 (20130101)
A61K 31/472 (20130101)
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 38/00 (20130101)
A61K 38/08 (20130101)
A61K 45/06 (20130101)
A61K 47/48415 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 207/12 (20130101)
C07D 401/12 (20130101)

Peptides
C07K 5/0205 (20130101)
C07K 7/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047384 Barbeau et al.
FUNDED BY
Department of Transportation (USDOT)
U.S. State Government
State of Florida
Florida Department of Transportation (FDOT)
APPLICANT(S) Sean J. Barbeau (Tampa, Florida);  Philip L. Winters (Tampa, Florida);  Rafael Perez (Temple Terrace, Florida);  Miguel Labrador (Tampa, Florida);  Nevine Georggi (Valrico, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Sean J. Barbeau (Tampa, Florida);  Philip L. Winters (Tampa, Florida);  Rafael Perez (Temple Terrace, Florida);  Miguel Labrador (Tampa, Florida);  Nevine Georggi (Valrico, Florida)
ABSTRACT Disclosed is an automated trip-purpose detection method that utilizes GPS Data collected by GPS-enabled devices. The GPS data is compared against a GIS map to obtain various spatial and location characteristics of the surrounding area. This information is then used to derive a traveler's trip purpose. In a preferred embodiment, the inventive method is implemented automatically without any needed manipulation of GIS data. Additionally, the method integrates location information as defined by the user for critical locations such as home and work. These personalized locations allow the method to immediately identify the two most common types of trips: work-related trips and trips returning home.
FILED Monday, January 14, 2008
APPL NO 12/013789
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Electric Digital Data Processing
G06F 17/3087 (20130101) Original (OR) Class
G06F 17/30241 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 1/10 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/18 (20130101)
H04L 67/22 (20130101)

Wireless Communication Networks
H04W 4/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 09045742 Curtiss, III et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Roy Curtiss, III (Paradise Valley, Arizona);  Javier Santander (Tempe, Arizona)
ASSIGNEE(S) The Arizona Board of Regents for and on behalf of Arizona State University (Tempe, Arizona)
INVENTOR(S) Roy Curtiss, III (Paradise Valley, Arizona);  Javier Santander (Tempe, Arizona)
ABSTRACT The present invention encompasses a recombinant Edwardsiella bacterium, and compositions and methods of use thereof.
FILED Friday, May 28, 2010
APPL NO 12/789869
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/02 (20130101)
A61K 2039/523 (20130101)

Peptides
C07K 14/24 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/36 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP25612 Deng et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
APPLICANT(S) Zhanao Deng (Riverview, Florida);  Brent K. Harbaugh (Bradenton, Florida)
ASSIGNEE(S) Florida Foundation Seed Producers, Inc. (Marianna, Florida)
INVENTOR(S) Zhanao Deng (Riverview, Florida);  Brent K. Harbaugh (Bradenton, Florida)
ABSTRACT A new and distinct cultivar of Caladium plant named ‘UF 4412’, characterized by its mounding growth habit, heart-shaped leaves that have a large red center, red primary veins, netted greyed-purple secondary veins, and green margins, and plants that are attractive in containers or landscapes.
FILED Thursday, March 14, 2013
APPL NO 13/815693
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 5/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 09044369 Goldish et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The United States of America, as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  Regards of the University of Minnesota (St. Paul, Minnesota)
INVENTOR(S) Gary D. Goldish (Plymouth, Minnesota);  Andrew Hansen (Apple Valley, Minnesota)
ABSTRACT The present invention relates to a novel approach to improving the use of wheelchairs by offering the ability for the wheelchair to transition between accommodation for a seated position, and accommodation for a standing position, more particularly, wherein the inventive mobile manual standing wheelchair allows for a standing position during the course of mobile use, and which also permits fixed gearing of multiple speeds that also accommodates forwards and backwards motion.
FILED Wednesday, October 03, 2012
APPL NO 13/644139
ART UNIT 3611 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 5/14 (20130101) Original (OR) Class
A61G 5/026 (20130101)
A61G 2005/128 (20130101)
A61G 2005/1051 (20130101)
A61G 2200/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047183 Shupp et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Cristopher Shupp (Belews Creek, North Carolina);  Gregory Bowman (Young Harris, Georgia)
ABSTRACT Systems and methods for detecting an issue with a message flow between two or more data systems. In an embodiment, at a first time, a number of first request messages and a number of first response messages transmitted or received during a first look-back period are determined. A first ratio is calculated based on these numbers and compared to an alerting threshold. If the first ratio is less than the alerting threshold, an alert is generated. Then, at a second time, a number of second request messages and a number of second response messages transmitted or received during a second look-back period are determined. A second ratio is calculated based on these numbers and compared to a clearing threshold. Based on this comparison, it is determined whether to maintain or clear the alert.
FILED Monday, January 14, 2013
APPL NO 13/741169
ART UNIT 2682 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 11/0709 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 09046373 Bandyopadhyay et al.
FUNDED BY
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Amrit Bandyopadhyay (Washington, District of Columbia);  Daniel Hakim (Silver Spring, Maryland);  Benjamin E. Funk (Hanover, Maryland);  Eric Asher Kohn (Washington, District of Columbia);  Carole A. Teolis (Glenn Dale, Maryland);  Gilmer L. Blankenship (Washington, District of Columbia)
ASSIGNEE(S) TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S) Amrit Bandyopadhyay (Washington, District of Columbia);  Daniel Hakim (Silver Spring, Maryland);  Benjamin E. Funk (Hanover, Maryland);  Eric Asher Kohn (Washington, District of Columbia);  Carole A. Teolis (Glenn Dale, Maryland);  Gilmer L. Blankenship (Washington, District of Columbia)
ABSTRACT A system and method for locating, tracking, and/or monitoring the status of personnel and/or assets (collectively “trackees”), both indoors and outdoors, is provided. Tracking data obtained from any number of sources utilizing any number of tracking methods may be provided as input to a mapping application. The mapping application generates position estimates for trackees using a suite of mapping tools to make corrections to the tracking data. The mapping application further uses information from building data, when available, to enhance position estimates. Indoor tracking methods including sensor fusion methods, map matching methods, and map building methods may be implemented compute a more accurate tracking estimate for trackees. Outdoor tracking methods may be implemented to enhance outdoor tracking data by combining tracking estimates such as inertial tracks with magnetic and/or compass data if and when available, and with GPS, if and when available.
FILED Friday, September 14, 2012
APPL NO 13/616350
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 17/38 (20130101)
G01C 21/16 (20130101)
G01C 21/165 (20130101) Original (OR) Class
G01C 21/206 (20130101)
G01C 21/3438 (20130101)
G01C 21/3626 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/0294 (20130101)
G01S 19/39 (20130101)
G01S 19/48 (20130101)
G01S 19/49 (20130101)

Wireless Communication Networks
H04W 4/028 (20130101)
H04W 4/043 (20130101)
H04W 64/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09047678 O'Hara et al.
FUNDED BY
Small Business Administration (SBA)
APPLICANT(S) Charles G. O'Hara (Columbus, Mississippi);  Anil Cheriyadat (Knoxville, Tennessee);  Suyoung Seo (Starkville, Mississippi);  Veeraraghavan Vijayaraj (Knoxville, Tennessee)
ASSIGNEE(S) Mississippi State University Research and Technology Corporation (, Mississippi)
INVENTOR(S) Charles G. O'Hara (Columbus, Mississippi);  Anil Cheriyadat (Knoxville, Tennessee);  Suyoung Seo (Starkville, Mississippi);  Veeraraghavan Vijayaraj (Knoxville, Tennessee)
ABSTRACT A method of determining change in a state of an object using images of the object, the method including providing a first image and a second image of the object, the first image and the second image being spaced apart in time, performing a plurality of pixel-based change detection algorithms to obtain a plurality of output difference products/images containing change information and pseudo change information, combining the plurality of output difference products to form a hybrid output difference product, and thresholding the output difference product to detect changes in the object.
FILED Monday, April 16, 2012
APPL NO 13/506384
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/0063 (20130101)

Image Data Processing or Generation, in General
G06T 7/0081 (20130101)
G06T 7/0097 (20130101)
G06T 7/2053 (20130101) Original (OR) Class
G06T 2207/10032 (20130101)
G06T 2207/20224 (20130101)
G06T 2207/30181 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 09044796 France
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S) TDA Research, Inc. (Wheat Ridge, Colorado)
ASSIGNEE(S) TDA Research, Inc. (Wheat Ridge, Colorado)
INVENTOR(S) Christopher Brian France (Arvada, Colorado)
ABSTRACT A method of encapsulating and safely transporting hazardous waste is disclosed. The method comprises the steps of: first, providing a waste object at a first location; second, covering the waste object with a closed cell polymer foam; third, allowing a sufficient time for the closed cell polymer foam to cure; and fourth, transporting the covered waste object to a second location. In another embodiment the method comprises the steps of: first, providing a waste object at a first location; second, treating the waste object to decontaminate or neutralize the hazardous waste; third, covering the waste object with a closed cell polymer foam; fourth, allowing a sufficient time for the closed cell polymer foam to cure; and fifth, transporting the covered waste object to a second location.
FILED Wednesday, March 12, 2014
APPL NO 14/206811
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus
A62D 2101/02 (20130101)

Disposal of Solid Waste
B09B 3/0033 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 09046373 Bandyopadhyay et al.
FUNDED BY
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Amrit Bandyopadhyay (Washington, District of Columbia);  Daniel Hakim (Silver Spring, Maryland);  Benjamin E. Funk (Hanover, Maryland);  Eric Asher Kohn (Washington, District of Columbia);  Carole A. Teolis (Glenn Dale, Maryland);  Gilmer L. Blankenship (Washington, District of Columbia)
ASSIGNEE(S) TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S) Amrit Bandyopadhyay (Washington, District of Columbia);  Daniel Hakim (Silver Spring, Maryland);  Benjamin E. Funk (Hanover, Maryland);  Eric Asher Kohn (Washington, District of Columbia);  Carole A. Teolis (Glenn Dale, Maryland);  Gilmer L. Blankenship (Washington, District of Columbia)
ABSTRACT A system and method for locating, tracking, and/or monitoring the status of personnel and/or assets (collectively “trackees”), both indoors and outdoors, is provided. Tracking data obtained from any number of sources utilizing any number of tracking methods may be provided as input to a mapping application. The mapping application generates position estimates for trackees using a suite of mapping tools to make corrections to the tracking data. The mapping application further uses information from building data, when available, to enhance position estimates. Indoor tracking methods including sensor fusion methods, map matching methods, and map building methods may be implemented compute a more accurate tracking estimate for trackees. Outdoor tracking methods may be implemented to enhance outdoor tracking data by combining tracking estimates such as inertial tracks with magnetic and/or compass data if and when available, and with GPS, if and when available.
FILED Friday, September 14, 2012
APPL NO 13/616350
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 17/38 (20130101)
G01C 21/16 (20130101)
G01C 21/165 (20130101) Original (OR) Class
G01C 21/206 (20130101)
G01C 21/3438 (20130101)
G01C 21/3626 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/0294 (20130101)
G01S 19/39 (20130101)
G01S 19/48 (20130101)
G01S 19/49 (20130101)

Wireless Communication Networks
H04W 4/028 (20130101)
H04W 4/043 (20130101)
H04W 64/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 09044503 Hersh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute on Drug Abuse (NIDA)
Non-Profit Organization (NPO)
Alzheimer\'s Disease and Related Disorders Association, Inc. (ADRDA)
APPLICANT(S) Louis B. Hersh (Lexington, Kentucky);  Hanjun Guan (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) Louis B. Hersh (Lexington, Kentucky);  Hanjun Guan (Lexington, Kentucky)
ABSTRACT Methods for treatment and/or prevention of Alzheimer's disease comprising inactivating peripheral AP in serum to a reduce A(3 in the brain. Methods comprise expression of amyloid peptide inactivating enzyme on bone marrow cells; and coupling of amyloid peptide inactivating enzyme to hematopoietic cells.
FILED Friday, August 26, 2005
APPL NO 11/661274
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 48/00 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/6494 (20130101)
C12N 15/86 (20130101)
C12N 2740/15043 (20130101)
C12N 2830/008 (20130101)
C12N 2830/48 (20130101)

Enzymes
C12Y 304/24011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 09044783 Brown et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) The United States Postal Service (Washington, District of Columbia)
INVENTOR(S) John W. Brown (Manassas, Virginia);  Edward F. Houston (Bristow, Virginia);  Juan A. Roman (Fairfax, Virginia);  Leung M. Shiu (Gaithersburg, Maryland);  Riley H. Mayhall (Germantown, Maryland);  William P. McConnell (Woodstock, Maryland);  Matthew G. Good (Eldersburg, Maryland);  Robert E. Hume (Woodstock, Maryland);  Darin Dickey (Owings Mills, Maryland)
ABSTRACT Embodiments of a system and method for unloading articles from a container of items for use in an automatic stack feeder are disclosed. The automatic stack feeder may comprise a belt, a moveable lower paddle, and a moveable upper paddle, wherein the lower paddle is configured to partially extend through a belt of the automatic stack feeder. The movement of the belt, the lower paddle, and the upper paddle are coordinated such that there is no need to interrupt the operation of the automatic stack feeder to unload the container.
FILED Tuesday, March 12, 2013
APPL NO 13/797731
ART UNIT 3652 — Material and Article Handling
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 1/00 (20130101) Original (OR) Class
B07C 1/025 (20130101)

Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables
B65H 1/025 (20130101)
B65H 1/30 (20130101)
B65H 1/263 (20130101)
B65H 2301/422542 (20130101)
B65H 2301/422544 (20130101)
B65H 2405/212 (20130101)
B65H 2701/1916 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 09044461 Quadros et al.
FUNDED BY
APPLICANT(S) The Research Foundation of State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation of State University of New York (Albany, New York)
INVENTOR(S) Edward V. Quadros (Brooklyn, New York);  Jeffrey M. Sequeira (Brooklyn, New York)
ABSTRACT The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention provides compositions and methods for the treatment and prevention of diseases and disorders associated with cobalamin deficiency, including compositions and methods that promote cobalamin uptake. In addition, the present invention provides compositions and methods for the detection, treatment, and prevention of diseases associated with deregulated cell growth, including, e.g., cancer and autoimmune disorders, including compositions and methods that inhibit cobalamin uptake.
FILED Wednesday, August 14, 2013
APPL NO 13/967199
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39583 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09044611 Zhao et al.
FUNDED BY
APPLICANT(S) Min Zhao (Davis, California);  Junfeng Feng (Shanghai, China PRC);  Lei Zhang (Chongqing, China PRC)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Min Zhao (Davis, California);  Junfeng Feng (Shanghai, China PRC);  Lei Zhang (Chongqing, China PRC)
ABSTRACT Systems and methods are provided for migrating cells implanted or endogenous in tissue. The system may include first and second delivery electrodes configured for insertion in tissue and a direct current (DC) power source operatively coupled to the first and second delivery electrodes. The system further may include a programmable controller operatively coupled to the DC power source, wherein the programmable controller is programmed to direct the DC power source to deliver an electric field between the first delivery electrode and the second delivery electrode at a stimulation to nonstimulation ratio sufficient to cause the cells to migrate within tissue selectively.
FILED Friday, March 15, 2013
APPL NO 13/831655
ART UNIT 3766 — AI & Simulation/Modeling
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/18 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/205 (20130101)
A61N 1/36082 (20130101)
A61N 1/36103 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048029 Hunter et al.
FUNDED BY
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ian W. Hunter (Lincoln, Massachusetts);  Eli Travis Paster (Cambridge, Massachusetts)
ABSTRACT Electrochemical redox supercapacitor. The supercapacitor includes two thin films of electrically conducting polymer separated by an ion-permeable membrane and including an electrolyte disposed between the two thin films. Electrical contacts are disposed on outer surfaces of the two thin films. The supercapacitor is flexible and may be rolled, folded on itself, or kept substantially flat. A suitable conducting polymer is polypyrrole. In another aspect, the invention is a method for making a redox supercapacitor.
FILED Tuesday, February 12, 2013
APPL NO 13/764991
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/22 (20130101)
H01G 9/0029 (20130101)
H01G 9/058 (20130101)
H01G 11/02 (20130101)
H01G 11/48 (20130101) Original (OR) Class
H01G 11/78 (20130101)
H01G 11/80 (20130101)
H01G 11/84 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/13 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/7022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 09048497 Amatucci et al.
FUNDED BY
APPLICANT(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
ASSIGNEE(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Glenn G. Amatucci (Peapack, New Jersey);  Anna Halajko (Parlin, New Jersey);  Fadwa Badway (Old Bridge, New Jersey)
ABSTRACT The described invention provides self-forming compositions as positive electrode materials. The described invention further provides electrode compositions related to an electrochemical energy storage cell comprising a metal, a glass former and lithium fluoride.
FILED Friday, October 25, 2013
APPL NO 14/063966
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 1/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/139 (20130101)
H01M 4/0423 (20130101)
H01M 4/0445 (20130101)
H01M 4/582 (20130101)
H01M 4/626 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 02, 2015.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2015/fedinvent-patents-20150602.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

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