FedInvent™ Patents

Patent Details for Tuesday, November 03, 2015

This page was updated on Monday, March 27, 2023 at 04:23 AM GMT

Department of Health and Human Services (HHS)

09173383 — Recombinant non-human mammalian model for hepatitis infection and immunopathogenesis

US 09173383	Su et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Lishan Su (Chapel Hill, North Carolina); Liguo Zhang (Chapel Hill, North Carolina); Michael Washburn (Durham, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Lishan Su (Chapel Hill, North Carolina); Liguo Zhang (Chapel Hill, North Carolina); Michael Washburn (Durham, North Carolina)
ABSTRACT	Provided herein is a recombinant non-human mammal having an immune system including human immune cells and having a liver including human liver cells, and methods for producing the same. Also provided are methods of screening a compound for activity in treating hepatitis, comprising: administering a test compound to a recombinant non-human mammal as described herein; and then detecting the presence or absence of said activity in said mammal (e.g., by biochemical assay), said presence of said activity in said mammal indicating that said compound has activity in treating hepatitis. Methods of making fusion cells useful for the production of human monoclonal antibodies are also provided.
FILED	Friday, February 20, 2009
APPL NO	12/918676
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Original (OR) Class A01K 67/0275 (20130101) A01K 2207/15 (20130101) A01K 2217/15 (20130101) A01K 2217/30 (20130101) A01K 2217/052 (20130101) A01K 2217/206 (20130101) A01K 2227/105 (20130101) A01K 2267/0337 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6475 (20130101) C12N 15/8509 (20130101)
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09173562 — Method and apparatus for diagnosing neovascularized tissues

US 09173562	Sardar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF)
APPLICANT(S)	Dhiraj Sardar (San Antonio, Texas); Andrew T. C. Tsin (Fair Oaks Ranch, Texas)
ASSIGNEE(S)	The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S)	Dhiraj Sardar (San Antonio, Texas); Andrew T. C. Tsin (Fair Oaks Ranch, Texas)
ABSTRACT	Disclosed is a method for detecting neovascularized tissue that includes placing a tissue in the path of a light beam, measuring a polarization shift of the light beam, and detecting neovascularized tissue if the measured polarization shift corresponds to a polarization shift of a neovascularized tissue. Also disclosed is an apparatus for detecting neovascularized tissue that includes a laser, a polarizer coupled to the laser, a tissue sample holder coupled to the polarizer, an analyzer coupled to the tissue sample holder, a detector coupled to the analyzer, and a data acquisition system coupled to the detector, wherein the data acquisition system is configured to measure a polarization shift of a light beam emitted by the laser and diagnose an ocular disease if the measured polarization shift corresponds to a polarization shift of a neovascularized tissue.
FILED	Friday, January 23, 2004
APPL NO	10/543001
ART UNIT	3777 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/1225 (20130101) Original (OR) Class A61B 5/0059 (20130101)
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09173589 — System and method for inertial magnetic resonance elastography driver for use with interventional medical device

US 09173589	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Jun Chen (Rochester, Minnesota); David A. Woodrum (Kasson, Minnesota); Kevin J. Glaser (Rochester, Minnesota); Richard L. Ehman (Rochester, Minnesota); Phillip J. Rossman (Rochester, Minnesota)
ASSIGNEE(S)	MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota)
INVENTOR(S)	Jun Chen (Rochester, Minnesota); David A. Woodrum (Kasson, Minnesota); Kevin J. Glaser (Rochester, Minnesota); Richard L. Ehman (Rochester, Minnesota); Phillip J. Rossman (Rochester, Minnesota)
ABSTRACT	A system and method for performing a magnetic resonance elastography (MRE) procedure using an MRI system to monitor operation of a medical device performing a medical procedure. The driver system includes a housing, a port located in the housing and connected to a driving power, and an inertial driver moved within the housing by the driving power. A passage is formed in the housing and extends from a first opening in the housing, through the inertial driver, and to a second opening in the housing. The inertial driver receives a medical device extending through the passage and engages the medical device to impart oscillatory motion thereto as the inertial driver is moved by the driving power. The imparted oscillatory motion travels along the medical device as a waveguide to deliver the oscillatory motion to tissue receiving the medical procedure to perform the MRE procedure.
FILED	Friday, March 30, 2012
APPL NO	13/435657
ART UNIT	3777 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 18/22 (20130101) A61B 2018/00577 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/285 (20130101) G01R 33/56358 (20130101)
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09173624 — System and method for multi-energy X-ray imaging using a polychromatic source

US 09173624	Chen
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Guang-Hong Chen (Madison, Wisconsin)
ABSTRACT	A system and method for generating multi-energy computed tomography images of a subject using a polychromatic x-ray source with single spectrum includes acquiring a measure of a polychromatic spectrum of a polychromatic x-ray beam generated by the polychromatic x-ray source. The method also includes acquiring attenuation data generated by operating the polychromatic x-ray source, segmenting the attenuation data based on a plurality of component criteria to create plurality of segmented datasets, and generating template data from the segmented datasets. Using the template data and the measure of the polychromatic spectrum, polychromatic synthetic data is generated. Using the template data and each of the segmented datasets, component synthetic data is generated. Using the attenuation data, the polychromatic synthetic data, and the component synthetic data, a plurality of multi-energy images, including separable images weighted for each of the component criteria, is reconstructed.
FILED	Monday, October 14, 2013
APPL NO	14/053211
ART UNIT	2884 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/52 (20130101) A61B 6/482 (20130101) Original (OR) Class A61B 6/5211 (20130101) A61B 6/5235 (20130101) A61B 6/5294 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/087 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101)
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09173771 — Ophthalmic surgical device for accessing tissue and for performing a capsulotomy

US 09173771	Keller
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Christopher Guild Keller (El Cerrito, California)
ASSIGNEE(S)	Mynosys Cellular Devices, Inc. (Fremont, California)
INVENTOR(S)	Christopher Guild Keller (El Cerrito, California)
ABSTRACT	A surgical device and procedure are provided for smoothly and easily accessing tissue to perform microsurgery, including a capsulotomy of a lens capsule of an eye. The device includes a handpiece with a tip for insertion into an incision in the cornea of the eye. A sliding element is disposed within the handpiece and a suction cup is mounted to the sliding element. The sliding element can be translated to move the suction cup into and out of the handpiece. A compression mechanism associated with the suction cup and the handpiece compresses the suction cup for deployment through the tip of the handpiece. The suction cup can expand inside the anterior chamber into a cutting position on the lens capsule. A cutting element mounted to the suction cup is used to cut a portion of the lens capsule and to remove the portion from the eye.
FILED	Monday, June 07, 2010
APPL NO	13/702305
ART UNIT	3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Diagnosis; Surgery; Identification A61B 17/32 (20130101) A61B 18/08 (20130101) A61B 2018/00291 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00754 (20130101) Original (OR) Class
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09173839 — Anionic lipids and lipid nano-structures and methods of producing and using same

US 09173839	Awasthi et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Vibhudutta Awasthi (Edmond, Oklahoma); Pallavi Lagisetty (Glen Allen Richmond, Virginia)
ASSIGNEE(S)	The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S)	Vibhudutta Awasthi (Edmond, Oklahoma); Pallavi Lagisetty (Glen Allen Richmond, Virginia)
ABSTRACT	Anionic non-phospholipids, as well as lipid nanostructures formed therefrom, are disclosed herein. Also disclosed are methods of producing and using same.
FILED	Monday, April 15, 2013
APPL NO	13/863000
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0026 (20130101) A61K 9/127 (20130101) Original (OR) Class A61K 9/1272 (20130101) A61K 9/1277 (20130101) A61K 38/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101)
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09173860 — S isomers of α-methyl hydrocinnamic acid for the treatment of blood disorders

US 09173860	Perrine et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Susan Park Perrine (Weston, Massachusetts); Douglas V. Faller (Weston, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Susan Park Perrine (Weston, Massachusetts); Douglas V. Faller (Weston, Massachusetts)
ABSTRACT	The present intervention generally relates to compositions comprising S-isomer of alpha-methyl-hydrocinnamic acid for the treatment and/or prevention of blood disorders and blood deficiencies, as well as methods for treating blood disorders and/or blood deficiency in a subject by administering a composition comprising S-isomer of alpha-methyl-hydrocinnamic acid to the subject to ameliorate at least one symptom associated with the blood disorder. Another aspect relates to administration of an S-isomer of alpha-methyl-hydrocinnamic acid stimulate multi-lineage hematopoietic cell production in a subject, for example, increasing the numbers of circulating neutrophils, erythrocytes and platelets. Accordingly, one aspect of the present invention relates to administration of S-isomer of alpha-methyl-hydrocinnamic acid, e.g., by oral administration to a subject for the treatment of blood disorders, for example but not limited to, hemaglobinaphthy, thalassemia and aplastic anemia. In some embodiments, the oral pharmaceutical formulation comprising an S-isomer of -α-methyl-hydrocinnamic acid can be used to increase red blood cell proliferation, or increase the proliferation of hemoglobin-expressing cells in a subject in need thereof, e.g., a subject having a blood deficiency such as a subject undergone chemotherapy or radiation exposure or radiation therapy. In some embodiments, a formulation comprising an S-isomer of alpha-methyl-hydrocinnamic acid (ST7S) can be used to simulate myelopiesis or erythropoiesis in a subject in need thereof.
FILED	Thursday, November 04, 2010
APPL NO	13/508236
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/0095 (20130101) A61K 31/16 (20130101) Original (OR) Class A61K 31/24 (20130101) A61K 31/165 (20130101)
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09173862 — Methods and compositions for treating and identifying compounds to treat age-related macular degeneration

US 09173862	McKay et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) U.S. State Government State of Arizona
APPLICANT(S)	Brian McKay (Marana, Arizona); John A. Martens (Tucson, Arizona)
ASSIGNEE(S)	Arizona Board of Regents, a Body Corporate of the State of Arizona, Acting for and on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Brian McKay (Marana, Arizona); John A. Martens (Tucson, Arizona)
ABSTRACT	The present invention provides methods for treating or limiting development of age-related macular degeneration, as well as methods for identifying compound suitable for such use.
FILED	Friday, April 17, 2009
APPL NO	12/937669
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/07 (20130101) A61K 31/07 (20130101) A61K 31/195 (20130101) Original (OR) Class A61K 31/195 (20130101) A61K 31/355 (20130101) A61K 31/355 (20130101) A61K 31/375 (20130101) A61K 31/375 (20130101) A61K 33/30 (20130101) A61K 33/30 (20130101) A61K 33/34 (20130101) A61K 33/34 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09173898 — Methods of treating giardiasis

US 09173898	Zheng et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Wei Zheng (Potomac, Maryland); Catherine Chen (Germantown, Maryland); Juan Jose Marugan (Gaithersburg, Maryland); Noel Southall (Potomac, Maryland); Christopher P. Austin (Potomac, Maryland); Andrey Galkin (Germantown, Maryland); Liudmila Kulakova (Germantown, Maryland); Osnat Herzberg (Rockville, Maryland)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); University of Maryland, College Park (College Park, Maryland)
INVENTOR(S)	Wei Zheng (Potomac, Maryland); Catherine Chen (Germantown, Maryland); Juan Jose Marugan (Gaithersburg, Maryland); Noel Southall (Potomac, Maryland); Christopher P. Austin (Potomac, Maryland); Andrey Galkin (Germantown, Maryland); Liudmila Kulakova (Germantown, Maryland); Osnat Herzberg (Rockville, Maryland)
ABSTRACT	Compounds useful for the treatment of giardiasis are described.
FILED	Wednesday, October 12, 2011
APPL NO	13/878832
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/28 (20130101) A61K 31/42 (20130101) A61K 31/69 (20130101) A61K 31/137 (20130101) A61K 31/145 (20130101) A61K 31/167 (20130101) A61K 31/285 (20130101) A61K 31/336 (20130101) A61K 31/345 (20130101) A61K 31/351 (20130101) A61K 31/396 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/436 (20130101) A61K 31/475 (20130101) A61K 31/498 (20130101) A61K 31/525 (20130101) A61K 31/704 (20130101) A61K 31/706 (20130101) A61K 31/714 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4995 (20130101) A61K 31/7068 (20130101) A61K 31/7135 (20130101) Original (OR) Class
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09173909 — Image guided protocol for cell generation

US 09173909	Lee
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	DRVision Technologies LLC (Bellevue, Washington)
ASSIGNEE(S)	DRVision Technologies LLC (Bellevue, Washington)
INVENTOR(S)	Shih-Jong James Lee (Bellevue, Washington)
ABSTRACT	Computerized image guided control method uses image quantification to dynamically monitor and control the cell generation process. The method acquires images during the cell generation steps and uses computer image analysis to automatically quantify the results of the cell generation steps. In one embodiment, the quantified results from the image analysis are used to determine the readiness of the cell generation step. In another embodiment, a remedial recovery sub-step for the cell generation step is also guided by the imaging results. In yet another embodiment, when a cell generation step is determined to have failed, the cell generation process is early terminated based on image guided decision.
FILED	Thursday, May 23, 2013
APPL NO	13/901553
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00127 (20130101)
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09173930 — Methods for detecting a mycobacterium tuberculosis infection

US 09173930	Lewinsohn et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	David M. Lewinsohn (Portland, Oregon); Deborah A. Lewinsohn (Portland, Oregon)
ASSIGNEE(S)	Oregon Health and Science University (Portland, Oregon); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	David M. Lewinsohn (Portland, Oregon); Deborah A. Lewinsohn (Portland, Oregon)
ABSTRACT	Methods for detecting an infection with Mtb in a subject are disclosed. The methods include detecting the presence of CD8⁺ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8⁺ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods also include detecting Mtb polypeptides and polynucleotides.
FILED	Friday, November 19, 2010
APPL NO	13/510869
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 49/00 (20130101)
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09173931 — Process for preparing polysaccharide-protein conjugate vaccines

US 09173931	Jessouroun et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Ellen Jessouroun (Rio de Janeiro, Brazil); Ivna Alana Freitas Brasileiro Da Silveira (Rio de Janeiro, Brazil); Renata Chagas Bastos (Rio de Janeiro, Brazil); Carl E. Frasch (Rockville, Maryland); Che-Hung Robert Lee (Silver Spring, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); Fiocruz (Rio de Janiero, Brazil)
INVENTOR(S)	Ellen Jessouroun (Rio de Janeiro, Brazil); Ivna Alana Freitas Brasileiro Da Silveira (Rio de Janeiro, Brazil); Renata Chagas Bastos (Rio de Janeiro, Brazil); Carl E. Frasch (Rockville, Maryland); Che-Hung Robert Lee (Silver Spring, Maryland)
ABSTRACT	Methods for the manufacture of polysaccharide-protein conjugate vaccines at high yield are provided. The methods involve reaction of a hydrazide group on one reactant with an aldehyde group on the other reactant. The reaction proceeds rapidly with a high conjugation efficiency. Simplified purification processes can be employed to separate the conjugate product from the unconjugated protein and polysaccharide and other small molecule by-products.
FILED	Friday, August 06, 2004
APPL NO	10/566898
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/09 (20130101) A61K 39/095 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 47/4833 (20130101) A61K 2039/62 (20130101) A61K 2039/6037 (20130101)
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09173932 — Vibrio cholerae O139 conjugate vaccines

US 09173932	Szu et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as represented by the Secretary, Department of Health and Human Servies (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Shousun Chen Szu (Potomac, Maryland); Zuzana Kossaczka (Bethesda, Maryland); John B. Robbins (New York, New York)
ABSTRACT	The disclosure pertains to conjugates of the capsular polysaccharide of Vibrio cholerae O139, or a structurally and/or immunologically related oligo- or poly-saccharide, and a carrier. These conjugates are useful as pharmaceutical compositions and/or vaccines to induce serum antibodies which have bactericidal (vibriocidal) activity against V. cholerae, in particular V. cholerae O139, and are useful to prevent, treat and/or reduce the severity of disease caused by V. cholerae infection, such as cholera. The present disclosure also relates to diagnostic tests for V. cholerae infection, and/or cholera caused by V. cholerae infection, using one or more of the oligo- or poly-saccharide-carrier conjugates or antibodies described above.
FILED	Monday, June 02, 2014
APPL NO	14/293745
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/107 (20130101) Original (OR) Class A61K 47/4833 (20130101)
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09173939 — Ester derivatives of androgen receptor modulators and methods for their use

US 09173939	Andersen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The University of British Columbia (Vancouver, Canada); British Columbia Cancer Agency Branch (Vancouver, Canada)
ASSIGNEE(S)	The University of British Columbia (Vancouver, BC, Canada); British Columbia Cancer Agency Branch (Vancouver, BC, Canada)
INVENTOR(S)	Raymond J. Andersen (Vancouver, Canada); Marianne D. Sadar (Vancouver, Canada); Javier Garcia Fernandez (Gijon, Canada); Nasrin R. Mawji (Burnaby, Canada); Jun Wang (New Westminster, Canada); Carmen Adriana Banuelos (Vancouver, Canada)
ABSTRACT	Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein R¹, R², R³, R⁴, R⁵, J¹, J², X, Z, n¹and n²are as defined herein, and wherein at least one of R¹, R²or R³is an alkyl, alkenyl, aryl or aralkyl ester, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided.
FILED	Friday, May 09, 2014
APPL NO	14/274528
ART UNIT	1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/222 (20130101) A61K 31/222 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 69/63 (20130101)
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09173950 — Vitamin D-ghrelin conjugates

US 09173950	Soliman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Extend Biosciences, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	Extend Biosciences, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Howard P. Sard (Arlington, Massachusetts); Mukkanti Amere (Woburn, Massachusetts)
ABSTRACT	The invention provides carriers that enhance the absorption, half-life or bioavailability of Ghrelin peptides. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties.
FILED	Saturday, November 15, 2014
APPL NO	14/542581
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) A61K 47/4813 (20130101) A61K 47/48107 (20130101) A61K 47/48215 (20130101) Original (OR) Class
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09173958 — Antibody buffering of a ligand in vivo

US 09173958	Foote et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Jefferson Foote (Seattle, Washington); Carol E. O'Hear (Seattle, Washington)
ASSIGNEE(S)	Arrowsmith Technologies Corporation (Seattle, Washington)
INVENTOR(S)	Jefferson Foote (Seattle, Washington); Carol E. O'Hear (Seattle, Washington)
ABSTRACT	Compositions and methods are provided in embodiments directed to maintaining a desired concentration range of one or more drugs in a subject, and in particular embodiments to maintaining a desired drug concentration in a body compartment in a subject, based on the surprising discovery that antibodies persist in solution in body compartments such that antibody-antigen equilibrium principles can counteract drug clearance mechanisms. One or more antibodies are selected that have a dissociation constant K_Dthat is similar to the desired drug concentration, wherein K_Dis independent of the affinity of the drug for a specific drug target (receptor) in the subject.
FILED	Tuesday, September 13, 2005
APPL NO	11/226055
ART UNIT	1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/39583 (20130101) A61K 39/39583 (20130101) A61K 45/06 (20130101) A61K 47/48376 (20130101) Original (OR) Class A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) C07K 16/40 (20130101) C07K 16/44 (20130101) C07K 2317/92 (20130101)
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09173963 — Diagnostic and treatment for chronic and acute phase myeloid leukemia

US 09173963	Reya et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Heart, Lung, and Blood Institute (NHLBI) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NIH Office of the Director (NIHOD)
APPLICANT(S)	Tannishtha Reya (San Diego, California); Hyog Y. Kwon (La Jolla, California); Takahiro Ito (San Diego, California); Dong-Wook Kim (Seoul, South Korea); Vivian Oehler (Seattle, Washington); Jerald Radich (Sammamish, Washington)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Tannishtha Reya (San Diego, California); Hyog Y. Kwon (La Jolla, California); Takahiro Ito (San Diego, California); Dong-Wook Kim (Seoul, South Korea); Vivian Oehler (Seattle, Washington); Jerald Radich (Sammamish, Washington)
ABSTRACT	Disclosed are methods of predicting responsiveness of a cancer cell to a tyrosine kinase inhibitor, and methods of predicting the risk of progression of a cancer cell to a more aggressive form. Also provided are methods of reducing proliferation or promoting differentiation of a cancer cell having reduced level of Numb or increased level of Msi. Further disclosed are methods of treating a mammalian subject having cancer and methods of assessing an agent for chemotherapeutic potential.
FILED	Friday, May 14, 2010
APPL NO	13/320324
ART UNIT	1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2740/10043 (20130101) C12N 2740/10071 (20130101) C12N 2810/6081 (20130101) C12N 2840/203 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57496 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101)
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09173966 — Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof

US 09173966	Chang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Christopher J. Chang (Berkeley, California); Carolyn R. Bertozzi (Berkeley, California); Genevieve C. van de Bittner (Berkeley, California); Elena A. Dubikovskaya (Lausanne, Switzerland)
ABSTRACT	The present disclosure features a condensation reaction and a luciferin-unmasking reaction that can be carried out under physiological conditions. In general, the condensation reaction involves reacting a bicyclic reactant with an aminothiol derivative, generating a luciferin or luciferin derivative. A luciferin can provide detectable luminescence. A luciferin derivative can be unmasked to provide detectable luminescence in a luciferin-unmasking reaction. The present disclosure provides bicyclic reactants and aminothiol derivatives suitable for use in the condensation reaction. The condensation and luciferin-unmasking reactions find use in a variety of applications, which are also provided.
FILED	Tuesday, January 15, 2013
APPL NO	13/742190
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) A61K 49/0021 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101)
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09174173 — Chemical processing cell with nanostructured membranes

US 09174173	Bhattacharyya et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Dibakar Bhattacharyya (Lexington, Kentucky); Scott R. Lewis (Wilmington, Delaware); Saurav Datta (Darien, Illinois)
ASSIGNEE(S)	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S)	Dibakar Bhattacharyya (Lexington, Kentucky); Scott R. Lewis (Wilmington, Delaware); Saurav Datta (Darien, Illinois)
ABSTRACT	A chemical processing cell includes an upstream membrane and a downstream membrane. The upstream membrane generates a first reaction product. The downstream membrane converts the first reaction product to a second reaction product.
FILED	Monday, April 30, 2012
APPL NO	13/459323
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Separation B01D 67/0079 (20130101) B01D 67/0088 (20130101) B01D 67/0093 (20130101) B01D 69/10 (20130101) Original (OR) Class B01D 71/022 (20130101) B01D 71/34 (20130101) B01D 71/40 (20130101) B01D 71/44 (20130101) B01D 2323/30 (20130101) B01D 2323/40 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 1/70 (20130101)
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09174176 — Ultrasonic dispersion apparatus, system, and method

US 09174176	Milner
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) U.S. Public Health Service (USPHS)
APPLICANT(S)	Henry Milner (Oceanside, California)
ASSIGNEE(S)	Disperse Systems, Inc. (Oceanside, California)
INVENTOR(S)	Henry Milner (Oceanside, California)
ABSTRACT	An apparatus, system, and method of dispersing solid forms of drugs or medications reliably and consistently may generally employ ultrasonic energy. The disclosed embodiments facilitate preparation of a liquid dose from solid medications for administration to a patient.
FILED	Thursday, January 08, 2004
APPL NO	10/754886
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 1/0005 (20130101) Original (OR) Class B01F 11/0283 (20130101) B01F 2215/0032 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/10 (20130101) B01J 2219/089 (20130101)
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09174917 — Bexarotene analogs

US 09174917	Wagner et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Carl E. Wagner (Glendale, Arizona); Peter W. Jurutka (Scottsdale, Arizona); Pamela A. Marshall (Glendale, Arizona); Arjan van der Vaart (Tampa, Florida)
ASSIGNEE(S)	Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	Carl E. Wagner (Glendale, Arizona); Peter W. Jurutka (Scottsdale, Arizona); Pamela A. Marshall (Glendale, Arizona); Arjan van der Vaart (Tampa, Florida)
ABSTRACT	The present invention relates to analogs of bexarotene and methods of use thereof.
FILED	Thursday, February 17, 2011
APPL NO	13/579551
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/03 (20130101) A61K 31/05 (20130101) A61K 31/10 (20130101) Acyclic or Carbocyclic Compounds C07C 63/66 (20130101) Original (OR) Class C07C 63/74 (20130101)
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09174936 — Retinal derivatives and methods for the use thereof for the treatment of visual disorders

US 09174936	Palczewski et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Krzysztof Palczewski (Bay Village, Ohio); Matthew Batten (Seattle, Washington)
ASSIGNEE(S)	University of Washington (Seattle, Washington)
INVENTOR(S)	Krzysztof Palczewski (Bay Village, Ohio); Matthew Batten (Seattle, Washington)
ABSTRACT	Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
FILED	Monday, March 07, 2011
APPL NO	13/042308
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/215 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/09 (20130101) Acyclic or Carbocyclic Compounds C07C 403/10 (20130101) C07C 403/12 (20130101) C07C 403/14 (20130101) Original (OR) Class C07C 403/20 (20130101) C07C 2101/10 (20130101) C07C 2101/16 (20130101)
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09174942 — IDO inhibitors

US 09174942	Mautino et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	NewLink Genetics Corporation (Ames, Iowa); Lankeanau Institute for Medical Research (Wynnewood, Pennsylvania)
ASSIGNEE(S)	NewLink Genetics Corporation (Ames, Iowa)
INVENTOR(S)	Mario R. Mautino (Ankeny, Iowa); Sanjeev Kumar (Ames, Iowa); Firoz Jaipuri (Ames, Iowa); Jesse Waldo (Huxley, Iowa); Tanay Kesharwani (Lake Katrine, New York); Nicholas N. Vahanian (Polk City, Iowa); Charles J. Link (Clive, Iowa); Judith Lalonde (Bryn Mawr, Pennsylvania); George Prendergast (Wynnewood, Pennsylvania); Alexander Muller (Wynnewood, Pennsylvania); William Malachowski (Bryn Mawr, Pennsylvania)
ABSTRACT	Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R¹, R⁴, and R⁵are defined herein. Such compounds and compositions are useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosuppression associated with an infectious disease.
FILED	Tuesday, April 29, 2014
APPL NO	14/264974
ART UNIT	1672 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4174 (20130101) Heterocyclic Compounds C07D 233/56 (20130101) C07D 233/58 (20130101) C07D 233/60 (20130101) C07D 233/61 (20130101) C07D 233/64 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) C07D 417/06 (20130101) C07D 498/04 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101)
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09174948 — Desferrithiocin polyether analogues

US 09174948	Bergeron, Jr.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Raymond J. Bergeron, Jr. (Gainesville, Florida)
ABSTRACT	A relatively non-toxic desazadesferrithiocin analog having the formula: wherein: R₁, R₂, R₄and R₅may be the same or different and may be H, straight or branched chain alkyl having up to 14 carbon atoms, e.g., methyl, ethyl, propyl and butyl, or arylalkyl wherein the aryl portion is hydrocarbyl and the alkyl portion is straight or branched chain, the arylalkyl group having up to 14 carbon atoms, R₂optionally being alkoxy having up to 14 carbon atoms; R₃is [(CH₂)_n—O]_x—[(CH₂)_n—O]_y-alkyl; n is, independently, an integer from 1 to 8; x is an integer from 1 to 8; y is an integer from 0 to 8, and R₃O may occupy any position on the phenyl ring except the 4-position, or a salt, hydrate or solvate thereof; and methods and compositions for treating the effects of trivalent metal, i.e., iron, overload.
FILED	Wednesday, November 21, 2012
APPL NO	13/683301
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 277/12 (20130101) Original (OR) Class
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09174951 — Glucose transporter inhibitors

US 09174951	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Ohio State University Research Foundation (Columbus, Ohio)
ASSIGNEE(S)	OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
INVENTOR(S)	Ching-Shih Chen (Upper Arlington, Ohio); Dasheng Wang (Dublin, Ohio); Samuel K. Kulp (Hillard, Ohio)
ABSTRACT	Thiazolidinedione compounds and pharmaceutically acceptable salts thereof are described. The compounds can be used in methods of treating cancer in a subject by administering to the subject a therapeutically effective amount of the compound. The compounds can also be used in methods of inhibiting glucose uptake in a cell by contacting the cell with the compound.
FILED	Thursday, March 28, 2013
APPL NO	14/386127
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 277/34 (20130101) Original (OR) Class
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09174969 — Indoline scaffold SHP-2 inhibitors and cancer treatment method

US 09174969	Wu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Jie Wu (Tampa, Florida); Nicholas J. Lawrence (Tampa, Florida); Said M. Sebti (Tampa, Florida)
ASSIGNEE(S)	UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S)	Jie Wu (Tampa, Florida); Nicholas J. Lawrence (Tampa, Florida); Said M. Sebti (Tampa, Florida)
ABSTRACT	The subject invention concerns methods and compounds for inhibiting Shp2. In one embodiment, a compound of the invention has a chemical structure as shown in formula I or II: wherein X, Y, and Z are independently N or S; R₁is cycloalkyl, heterocycloalkyl, aryl, or heteroaryl, any of which can be optionally substituted with one or more of halogen; alkyl; heteroalkyl; —COOH; —C(R₃)₃, wherein R₃can independently be any of —H or halogen; or —OR₄, wherein R₄can be any of H, alkyl, or heteroalkyl; R₂is alkyl, alkylcarbonyl, heteroalkylcarbonyl, aryl, arylcarbonyl, heterocycloalkylcarbonyl, cycloalkylcarbonyl, or —C(O)NR₆R₇, any of which can be optionally substituted with one or more of halogen; alkyl; heteroalkyl; carbonyl; —OR₄, wherein R₄can be —H, alkyl, or heteroalkyl; —OH; —C(R₃)₃, wherein R₃can independently be any of —H or halogen; aryl, which can be substituted with one or more of halogen or —OR₄; heterocycloalkyl; or —C(O)OR₅, wherein R₅can be —H or alkyl; R₆and R₇are independently —H, alkyl, heteroalkyl, aryl, or heteroaryl; and R′ is H or alkyl; or a pharmaceutically acceptable salt or hydrate thereof.
FILED	Tuesday, July 21, 2009
APPL NO	13/055113
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 209/08 (20130101) C07D 215/36 (20130101) C07D 405/06 (20130101) Original (OR) Class
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09174972 — Cognition enhancing compounds and compositions, methods of making, and methods of treating

US 09174972	Abraham et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	NeuroSolis, Inc. (Madison, Wisconsin)
ASSIGNEE(S)	NeuroSolis, Inc. (Madison, Wisconsin)
INVENTOR(S)	Brent D. Abraham (Verona, Wisconsin); Richard R. Copp (Oregon, Wisconsin); James G. Farnham (Madison, Wisconsin); Seth A. Hanson (Madison, Wisconsin); Michael L. Hendrickson (Madison, Wisconsin); Jeffrey C. Ockuly (Madison, Wisconsin); Trevor M. Twose (Fitchburg, Wisconsin); Melinda L. Verdone (Waunakee, Wisconsin)
ABSTRACT	The invention relates generally to muscarinic agonists, which are useful for stimulating muscarine receptors, and treating cognitive disorders. Included among the muscarinic agonists disclosed herein are oxadiazole derivatives, compositions, and preparations thereof. Methods of synthesizing oxadiazole compounds also are provided. This disclosure also relates in part to compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. This disclosure relates in part to methods of treating animals such as humans by administering such compositions.
FILED	Friday, March 08, 2013
APPL NO	13/791251
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 403/04 (20130101) C07D 413/04 (20130101) Original (OR) Class C07D 417/04 (20130101)
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09174988 — Small molecule inhibitors of hepatitis C virus

US 09174988	Snyder et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	John K. Snyder (Harvard, Massachusetts); Wanguo Wei (San Diego, California); Feng Ni (Allston, Massachusetts); Arthur Donny Strosberg (Palm Beach, Florida); Eliane Leuwenkroon (Palm Beach, Florida); Smitha Kota (Wellington, Florida); Virginia Ngocthanh Takahashi (Rockville, Maryland)
ASSIGNEE(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S)	John K. Snyder (Harvard, Massachusetts); Wanguo Wei (San Diego, California); Feng Ni (Allston, Massachusetts); Arthur Donny Strosberg (Palm Beach, Florida); Smitha Kota (Wellington, Florida); Virginia Ngocthanh Takahashi (Rockville, Maryland)
ABSTRACT	The invention provides derivatives and analogs of triazatetracyclo[7.7.0.0^1,13.0^2,7]-hexadeca-2,4,6,10,12-pentaenes, 5,7,11-triazatetracyclo[8.7.0.0^1,6.0^12,17]-heptadeca-6,8,12,14,16-pentaenes, pharmaceutical compositions comprising these compounds and methods for treatment of hepatitis C viral infections using these compounds.
FILED	Wednesday, October 27, 2010
APPL NO	13/504822
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 471/18 (20130101) Original (OR) Class C07D 471/22 (20130101) C07D 487/18 (20130101)
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09174990 — 2-amino-9-[(2-hydroxymethyl) cyclopropylidenemethyl] purines as antiviral agents

US 09174990	Zemlicka et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Jiri Zemlicka (Warren, Michigan); John C. Drach (Ann Arbor, Michigan); Xinchao Chen (Schenectady, New York)
ASSIGNEE(S)	WAYNE STATE UNIVERSITY (Detroit, Michigan); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S)	Jiri Zemlicka (Warren, Michigan); John C. Drach (Ann Arbor, Michigan); Xinchao Chen (Schenectady, New York)
ABSTRACT	Compounds which are active against viruses have the following Formulas: wherein B is 2-aminopurine-9-yl, which may be unsubstituted or substituted in the 6 position with NHR₁, OR₂, or SR₃; R₁is selected from the group consisting of alkyl, alkenyl, alkynyl, and C_4-18cycloalkyl, any of which may be optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl; R₂is selected from the group consisting of C_2-18alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl, and aryl; and R₃is selected from the group consisting of alkyl, alkenyl, alkynyl, and cycloalkyl, any of which may be branched or unbranched and optionally substituted with one or more members of the group consisting of hydroxy, halo, amino, acyl, cycloalkyl, heterocyclyl and aryl.
FILED	Thursday, February 15, 2007
APPL NO	11/707248
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 473/00 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65616 (20130101)
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09174999 — Methods and compositions for studying, imaging, and treating pain

US 09174999	Du Bois et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Justin Du Bois (Palo Alto, California); John Mulcahy (Stanford, California); Brian Andresen (Menlo Park, California); David C. Yeomans (Sunnyvale, California); Sandip Biswal (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Justin Du Bois (Palo Alto, California); John Mulcahy (Stanford, California); Brian Andresen (Menlo Park, California); David C. Yeomans (Sunnyvale, California); Sandip Biswal (Stanford, California)
ABSTRACT	Saxitoxin analog compounds, compositions, pharmaceutical compositions, methods of synthesis of saxitoxin analogs, methods of imaging, methods of treatment, including methods of treating pain, are provided. Saxitoxin (STX), gonyautoxin (GTX), and zetekitoxin, and variant STX compounds bind to sodium channels and are effective to reduce or block flow of sodium ions through such channels. Such channel block affects nerve and muscle action, and may be effective to reduce or block pain sensations, relax muscles, reduce muscle spasm, and reduce wrinkles. STX analog binding to sodium channels may also be useful to locate, image, or mark sodium channels, and so be useful in studying sodium channels and sodium channel disorders, and in the diagnosis and treatment of patients suffering from sodium channel disorders. In embodiments, the variant STX compounds include conjugates having increased serum half-life as compared to STX when administered to a subject. In embodiments, the present disclosure provides a method for alleviating pain in a subject in need of treatment, the method comprising administering to the subject an effective amount of a saxitoxin analog compound, or a pharmaceutically acceptable salt, isomer, tautomer or prodrug thereof, whereby pain in said subject is alleviated.
FILED	Friday, May 07, 2010
APPL NO	12/800053
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class
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09175001 — [1,3] dioxolo [4,5-g] [1,2,4] triazolo [1,5-a] quinoline derivatives as inhibitors of the late SV40 factor (LSF) for use in treating cancer

US 09175001	Schaus et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S)	TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S)	Scott E. Schaus (Boston, Massachusetts); Ulla Hansen (Bedford, Massachusetts); Joshua A. Bishop (Southborough, Massachusetts)
ABSTRACT	The present invention relates generally to [1,3]dioxolo[4,5-g]quinoline-6(5H)thione and [1,3]dioxolo[4,5-g][1,2,4]triazolo[1,5-a]quinoline derivatives and/or compositions for use in inhibiting, preventing and/or treating cancer, e.g. hepatocellular carcionoma (HCC). In some embodiments, the invention relates to the use of small-molecule compounds to inhibit, prevent and/or treat expression of the transcription factor Late SV40 Factor (LSF) for treatment of HCC or other cancer types.
FILED	Tuesday, October 02, 2012
APPL NO	14/349230
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 491/056 (20130101) Original (OR) Class C07D 491/147 (20130101)
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09175002 — Synthesis and use of dual tyrosyl-DNA phosphodiesterase I (Tdp1)—topoisomerase I (Top1) inhibitors

US 09175002	Cushman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Mark S. Cushman (West Lafayette, Indiana); Trung X. Nguyen (West Lafayette, Indiana); Martin M. Conda-Sheridan (Evanston, Illinois); Yves George Pommier (Bethesda, Maryland)
ABSTRACT	The invention described herein pertains to the synthesis and use of certain N-substituted indenoisoquinoline compounds which inhibit the activity Tyrosyl-DNA Phosphodiesterase I (Tdp1) or Topoisomerase I (Top1) or both, or otherwise demonstrate anticancer activity. Also disclosed are novel N-substituted indenoisoquinoline compounds and pharmaceutical compositions comprising the novel N-substituted indenoisoquinoline compounds.
FILED	Monday, November 10, 2014
APPL NO	14/537630
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 221/18 (20130101) C07D 401/06 (20130101) C07D 491/056 (20130101) Original (OR) Class
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09175016 — Prochelators useful for inhibiting metal-associated toxicity

US 09175016	Franz et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Duke University (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Katherine J. Franz (Durham, North Carolina); Marina G. D. Leed (Durham, North Carolina)
ABSTRACT	Prochelator compounds of Formula I or Formula II: are described, along with methods of using the same and pharmaceutical formulations or compositions containing the same.
FILED	Thursday, January 30, 2014
APPL NO	14/168528
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) C07F 5/025 (20130101) C07F 5/027 (20130101) Original (OR) Class
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09175029 — Aminoglycosides and uses thereof in treating genetic disorders

US 09175029	Baasov et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Technion Research and Development Foundation Limited (Haifa, Israel)
ASSIGNEE(S)	Technion Research and Development Foundation Limited (Haifa, Israel)
INVENTOR(S)	Timor Baasov (Haifa, Israel); Dana Atia-Glikin (Carmiel, Israel); Jeyakumar Kandasamy (Trichy, India); Valery Belakhov (Haifa, Israel)
ABSTRACT	A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5″ position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R₁is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.
FILED	Monday, August 18, 2014
APPL NO	14/461477
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/7036 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 5/06 (20130101) C07H 13/04 (20130101) C07H 15/23 (20130101) Original (OR) Class
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09175033 — Methods for preparing complex multivalent immunogenic conjugates

US 09175033	Lee
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Che-Hung Robert Lee (Silver Spring, Maryland)
ABSTRACT	Methods for preparing complex multivalent immunogenic conjugates that include simultaneously reacting a plurality or immunogenic-distinct polysaccharides with at least one protein to make the complex multivalent immunogenic conjugates. The simultaneous reaction involves reaction of a hydrazide group on one reactant with an aldehyde or cyanate ester group on the other reactant.
FILED	Tuesday, August 06, 2013
APPL NO	13/960691
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/116 (20130101) A61K 39/385 (20130101) A61K 2039/62 (20130101) A61K 2039/6037 (20130101) Peptides C07K 1/084 (20130101) Original (OR) Class
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09175038 — Peptide mimetic ligands of polo-like kinase 1 polo box domain and methods of use

US 09175038	Burke, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Terrence R. Burke, Jr. (Bethesda, Maryland); Fa Liu (Indianapolis, Indiana); Kyung S. Lee (Gaithersburg, Maryland); Jung-Eun Park (Bethesda, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Terrence R. Burke, Jr. (Bethesda, Maryland); Fa Liu (Indianapolis, Indiana); Kyung S. Lee (Gaithersburg, Maryland); Jung-Eun Park (Bethesda, Maryland)
ABSTRACT	Found in various eukaryotic organisms, polo-like kinases (collectively, Plks) are a conserved subfamily of Ser/Thr protein kinases that play critical roles in cell proliferation. Provided herein are compounds that specifically inhibit the activity of Plks, specifically Plk1. Further provided herein are methods for use of the compounds for the treatment of hyperproliferative disorders, particularly cancer. Also provided are uses of the compounds for the preparation of a medicament.
FILED	Monday, May 17, 2010
APPL NO	13/320726
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class
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09175039 — Methods and compositions for tumor vaccination and therapy

US 09175039	Darnell
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	ROCKEFELLER UNIVERSITY (THE) (New York, New York)
ASSIGNEE(S)	The Rockefeller University (New York, New York)
INVENTOR(S)	Robert B. Darnell (New York, New York)
ABSTRACT	The present invention relates to peptide vaccines, pharmaceutical compositions thereof, and associated methodologies that promote the immune-mediated regression of tumors expressing an onconeural antigen, e.g. a cdr-2 antigen, HuD antigen. The cancer peptide vaccines of the present invention are antigenic peptides capable of being faithfully presented on the MHC I complex of a target cell or antigen presenting cell. This external cellular presentation of these peptides promotes a specific cytotoxic T lymphocyte (CTL)-mediated immune response against tumor cells expressing these proteins, thereby, inducing immunological reactivity.
FILED	Friday, August 23, 2013
APPL NO	13/974796
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 2035/122 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 14/4748 (20130101)
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09175041 — Crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline, and methods for preparing dolamethylleuine and dolaphenvaline

US 09175041	Pettit et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) U.S. State Government State of Arizona
APPLICANT(S)	George R. Pettit (Paradise Valley, Arizona); Thomas Smith (Tempe, Arizona); Jun-Ping Xu (Chandler, Arizona); Delbert Herald (Tempe, Arizona)
ASSIGNEE(S)	Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	George R. Pettit (Paradise Valley, Arizona); Thomas Smith (Tempe, Arizona); Jun-Ping Xu (Chandler, Arizona); Delbert Herald (Tempe, Arizona)
ABSTRACT	The present invention relates to the crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline. The present invention also relates to processes for preparing dolamethylleuine and dolaphenvaline. The present invention further relates to computer readable medium with crystal structural data and/or information stored thereon.
FILED	Wednesday, April 25, 2012
APPL NO	14/113682
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Acyclic or Carbocyclic Compounds C07C 227/18 (20130101) Peptides C07K 5/0205 (20130101) C07K 7/54 (20130101) Original (OR) Class Electric Digital Data Processing G06F 19/701 (20130101)
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09175043 — Agents providing controls and standards for immuno-precipitation assays

US 09175043	Bernstein et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	Bradley E. Bernstein (Cambridge, Massachusetts); Alon Goren (Cambridge, Massachusetts)
ASSIGNEE(S)	The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S)	Bradley E. Bernstein (Cambridge, Massachusetts); Alon Goren (Cambridge, Massachusetts)
ABSTRACT	Control agents for immuno-precipitation assays, methods of using the control agents and kits comprising the control agents are provided.
FILED	Friday, March 29, 2013
APPL NO	13/853216
ART UNIT	1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 9/00 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6804 (20130101) C12Q 1/6804 (20130101) C12Q 1/6804 (20130101) C12Q 2525/203 (20130101) C12Q 2525/203 (20130101) C12Q 2525/203 (20130101) C12Q 2545/101 (20130101) C12Q 2545/101 (20130101) C12Q 2545/101 (20130101) C12Q 2565/113 (20130101) C12Q 2565/113 (20130101) C12Q 2600/166 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101)
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09175057 — Immunogenic peptides and methods of use

US 09175057	Schlom et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Jeffrey Schlom (Potomac, Maryland); Kwong-Yok Tsang (Bethesda, Maryland); Ira H. Pastan (Potomac, Maryland)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Jeffrey Schlom (Potomac, Maryland); Kwong-Yok Tsang (Bethesda, Maryland); Ira H. Pastan (Potomac, Maryland)
ABSTRACT	The PAGE4 gene is expressed in reproductive tissues, and is expressed in reproductive cancers, such as prostate cancer, uterine cancer, and testicular cancer. Immunogenic PAGE4 polypeptides are disclosed herein, as are nucleic acids encoding the immunogenic PAGE4 polypeptides, vectors including these polynucleotides, and host cells transformed with these vectors. These polypeptides, polynucleotides, vectors, and host cells can be used to induce an immune response to PAGE4. Diagnostic methods to detect PAGE4 are also described.
FILED	Thursday, February 10, 2011
APPL NO	13/025094
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 39/0011 (20130101) Peptides C07K 14/82 (20130101) C07K 14/4748 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2799/023 (20130101) C12N 2800/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/70517 (20130101)
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09175062 — Human soluble receptor for advanced glycation end products (sRAGE), methods of preparing human sRAGE, and treatment methods using sRAGE

US 09175062	Lin et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Li Lin (Baltimore, Maryland); Sungha Park (Seoul, South Korea); Wen Wei (Cockeysville, Maryland); Rui-Ping Xiao (Baltimore, Maryland); Mark I. Talan (Baltimore, Maryland); Edward G. Lakatta (Bel Air, Maryland)
ABSTRACT	The present disclosure provides a method for recombinant production of human sRAGE in mammalian cells, as well as a human sRAGE having a mammalian post-translational modification and compositions thereof. The present disclosure also provides a method of treating a vascular disease, injury, or inflammation in a mammal by administering to a mammal with a vascular disease, injury, or inflammation a composition comprising human sRAGE having a mammalian post-translational modification, thereby treating the vascular disease, injury, or inflammation in the mammal.
FILED	Thursday, January 03, 2013
APPL NO	14/368374
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Peptides C07K 14/705 (20130101) C07K 14/70503 (20130101) Original (OR) Class
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09175063 — Anti-angiogenic agent and methods of using such agent

US 09175063	Liu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Zhi-Ren Liu (Marietta, Georgia); Jenny J. Yang (Marietta, Georgia); Yin Lu (Atlanta, Georgia)
ASSIGNEE(S)	Georgia State University Research Foundation (Atlanta, Georgia)
INVENTOR(S)	Zhi-Ren Liu (Marietta, Georgia); Jenny J. Yang (Marietta, Georgia); Yin Lu (Atlanta, Georgia)
ABSTRACT	Anti-angiogenic agents or polypeptides comprising an amino acid segment substantially similar to domain one of CD2 wherein the polypeptide has a β-sheet formed by two segments. Methods of using such agents and polypeptide are also included.
FILED	Wednesday, July 13, 2011
APPL NO	13/739241
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) A61K 45/06 (20130101) Peptides C07K 14/70507 (20130101) Original (OR) Class
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09175069 — Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof

US 09175069	Garcia-Sastre et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Icahn School of Medicine at Mount Sinai (New York, New York)
ASSIGNEE(S)	Icahn School of Medicine at Mount Sinai (New York, New York)
INVENTOR(S)	Adolfo Garcia-Sastre (New York, New York); Peter Palese (New York, New York); Taia T. Wang (New York, New York)
ABSTRACT	Provided herein are methods of producing neutralizing monoclonal antibodies, by cyclical immunization, that cross-react with strains of Influenza virus of the same subtype or different subtypes. Also provided herein are compositions comprising such antibodies and methods of using such antibodies to diagnose, prevent or treat Influenza virus disease.
FILED	Thursday, January 23, 2014
APPL NO	14/162354
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101)
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09175070 — Neutralizing antibodies to HIV-1 and their use

US 09175070	Mascola et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	John R. Mascola (Rockville, Maryland); Richard T. Wyatt (San Diego, California); Xueling Wu (Potomac, Maryland); Yuxing Li (Boyds, Maryland); Carl-Magnus Hogerkorp (Vellinge, Sweden); Mario Roederer (Washington, District of Columbia); Zhi-yong Yang (Potomac, Maryland); Gary J. Nabel (Cambridge, Massachusetts); Peter D. Kwong (Washington, District of Columbia); Tongqing Zhou (Boyds, Maryland); Mark Connors (Bethesda, Maryland); William R. Schief (Encinitas, California)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia); University of Washington (Seattle, Washington)
INVENTOR(S)	John R. Mascola (Rockville, Maryland); Richard T. Wyatt (San Diego, California); Xueling Wu (Potomac, Maryland); Yuxing Li (Boyds, Maryland); Carl-Magnus Hogerkorp (Vellinge, Sweden); Mario Roederer (Washington, District of Columbia); Zhi-yong Yang (Potomac, Maryland); Gary J. Nabel (Cambridge, Massachusetts); Peter D. Kwong (Washington, District of Columbia); Tongqing Zhou (Boyds, Maryland); Mark Connors (Bethesda, Maryland); William R. Schief (Encinitas, California)
ABSTRACT	Monoclonal neutralizing antibodies are disclosed that specifically bind to the CD4 binding site of HIV-1 gp120. Monoclonal neutralizing antibodies also are disclosed that specifically bind to HIV-1 gp41. The identification of these antibodies, and the use of these antibodies are also disclosed. Methods are also provided for enhancing the binding and neutralizing activity of any antibody using epitope scaffold probes.
FILED	Friday, September 24, 2010
APPL NO	13/498125
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/92 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/10011 (20130101) C12N 2740/16011 (20130101) C12N 2740/16111 (20130101)
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09175077 — Nucleic acids encoding biologically active polypeptides derived from a novel early stage pregnancy factor designated maternin (MA)

US 09175077	Gallo et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Robert C. Gallo (Bethesda, Maryland); Joseph Bryant (Baltimore, Maryland); Yanto Lunardi-Iskandar (Gaithersburg, Maryland)
ASSIGNEE(S)	NOBEL BIOSCIENCES LLC (Gaithersburg, Maryland)
INVENTOR(S)	Robert C. Gallo (Bethesda, Maryland); Joseph Bryant (Baltimore, Maryland); Yanto Lunardi-Iskandar (Gaithersburg, Maryland)
ABSTRACT	The invention relates to nucleotides encoding therapeutic polypeptides and fragments thereof isolated from beta-human chorionic gonadotropin (β-hCG) found in human early pregnancy urine, now synthetically produced and designated Maternin. The therapeutic polypeptides and their functional equivalents are useful in treating and/or preventing various medical conditions. Examples of therapeutic effects of the therapeutic polypeptides include anti-HIV, anti-cancer, anti-wasting, prohematopoietic (e.g., anemias, radiation-mediated bone marrow damage, and trauma-mediated blood loss), and anti-angiogenic effects. The invention also provides pharmaceutical compositions comprising the therapeutic polypeptides, as well as methods for using the therapeutic polypeptides, functional equivalents and/or pharmaceutical compositions in the treatment and/or prevention of such medical conditions.
FILED	Monday, June 13, 2011
APPL NO	13/159285
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) Peptides C07K 14/59 (20130101) C07K 16/26 (20130101) Original (OR) Class C07K 2319/00 (20130101)
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09175090 — Methods of using an antibody to inhibit WNT-mediated signaling in cancer

US 09175090	Lee et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S)	Ethan Lee (Brentwood, Tennessee); Pampee P. Young (Brentwood, Tennessee); Josiane Eid (Nashville, Tennessee); Robert Carnahan (Franklin, Tennessee); Curtis Thorne (Dallas, Texas); Kelly Meyers (Gallatin, Tennessee)
ABSTRACT	The present invention is directed to monoclonal antibodies and fragments thereof directed to LRP5/6 that find use in the prevention and treatment of cardiac remodeling and cancer. Also disclosed are methods for using such monoclonal antibodies in the prevention and treatment of such diseases.
FILED	Tuesday, July 29, 2014
APPL NO	14/446073
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 2005/1098 (20130101) Peptides C07K 16/30 (20130101) Original (OR) Class C07K 16/2863 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101)
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09175264 — Postnatal stem cells and uses thereof

US 09175264	Shi et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	Songtao Shi (Irvine, California); Pamela Gehron Robey (Bethesda, Maryland); Stan Gronthos (Colonel Light Gardens, Australia); Masako Miura (Kyoto, Japan)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S)	Songtao Shi (Irvine, California); Pamela Gehron Robey (Bethesda, Maryland); Stan Gronthos (Colonel Light Gardens, Australia); Masako Miura (Kyoto, Japan)
ABSTRACT	The invention generally relates to postnatal dental stem cells and methods for their use. More specifically, the invention relates in one aspect to postnatal dental pulp stem cells, use of the cells to generate dentin, and differentiation of the cells. In another aspect, the invention relates to human postnatal deciduous dental pulp multipotent stem cells, use of the cells to generate dentin, and differentiation of the cells.
FILED	Saturday, April 19, 2003
APPL NO	10/553633
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) C12N 5/0618 (20130101) Original (OR) Class C12N 5/0664 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2506/1361 (20130101) C12N 2533/54 (20130101)
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09175274 — High activity mutants of butyrylcholinesterase for cocaine hydrolysis

US 09175274	Zhan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S)	University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S)	Chang-Guo Zhan (Lexington, Kentucky); Fang Zheng (Lexington, Kentucky); Wenchao Yang (Lexington, Kentucky)
ABSTRACT	Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (−)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (−)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.
FILED	Wednesday, August 27, 2014
APPL NO	14/470751
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/18 (20130101) Original (OR) Class Enzymes C12Y 301/01008 (20130101)
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09175285 — Potent non-urea inhibitors of soluble epdxide hydrolase

US 09175285	Landry et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Donald W. Landry (New York, New York); Yuli Xie (New York, New York); Yidong Lu (New York, New York); Gangli Gong (Elmhurst, New York); Shi-Xian Deng (White Plains, New York); Kirsten Alison Rinderspacher (Bronx, New York)
ABSTRACT	The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
FILED	Monday, February 17, 2014
APPL NO	14/182175
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 211/62 (20130101) C07D 211/96 (20130101) C07D 401/12 (20130101) C07D 409/12 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/591 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/99 (20130101) Original (OR) Class
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09175287 — In vivo production of small interfering RNAs that mediate gene silencing

US 09175287	Zamore et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Phillip D. Zamore (Northboro, Massachusetts); Juanita McLachlan (Worcester, Massachusetts); Gyorgy Hutvagner (Castle Hill, Australia); Alla Grishok (New York, New York); Craig C. Mello (Barrington, Rhode Island)
ABSTRACT	The invention provides engineered RNA precursors that when expressed in a cell are processed by the cell to produce targeted small interfering RNAs (siRNAs) that selectively silence targeted genes (by cleaving specific mRNAs) using the cell's own RNA interference (RNAi) pathway. By introducing nucleic acid molecules that encode these engineered RNA precursors into cells in vivo with appropriate regulatory sequences, expression of the engineered RNA precursors can be selectively controlled both temporally and spatially, i.e., at particular times and/or in particular tissues, organs, or cells.
FILED	Monday, September 09, 2013
APPL NO	14/021845
ART UNIT	1674 — Organic Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/05 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/8509 (20130101) C12N 2310/14 (20130101) C12N 2310/53 (20130101) C12N 2310/111 (20130101) C12N 2330/30 (20130101) C12N 2517/02 (20130101) C12N 2799/021 (20130101) C12N 2830/008 (20130101)
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09175310 — Rapid and prolonged immunologic-therapeutic

US 09175310	Tang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	De-Chu C. Tang (Birmingham, Alabama)
ASSIGNEE(S)	ALTIMMUNE INC (Gaithersburg, Maryland)
INVENTOR(S)	De-Chu C. Tang (Birmingham, Alabama)
ABSTRACT	The present invention shows that intranasal administration of E1/E3-defective adenovirus particles may confer rapid and broad protection against viral and bacterial pathogens in a variety of disease settings. Protective responses lasted for many weeks in a single-dose regimen in animal models. When a pathogen-derived antigen gene was inserted into the E1/E3-defective adenovirus genome, the antigen-induced protective immunity against the specific pathogen was elicited before the adenovirus-mediated protective response declined away, thus conferring rapid, prolonged, and seamless protection against pathogens. In addition to E1/E3-defective adenovirus, other bioengineered non-replicating vectors encoding pathogen-derived antigens may also be developed into a new generation of rapid and prolonged immunologic-therapeutic (RAPIT).
FILED	Wednesday, March 21, 2012
APPL NO	13/426037
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/07 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/155 (20130101) A61K 2039/58 (20130101) A61K 2039/543 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/10034 (20130101) C12N 2710/10043 (20130101) C12N 2760/16134 (20130101)
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09175311 — Polycistronic vector for human induced pluripotent stem cell production

US 09175311	Townes et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Tim Townes (Birmingham, Alabama); Kevin M. Pawlik (Birmingham, Alabama)
ASSIGNEE(S)	The UAB Research Foundation (Birmingham, Alabama)
INVENTOR(S)	Tim Townes (Birmingham, Alabama); Kevin M. Pawlik (Birmingham, Alabama)
ABSTRACT	Methods of producing induced pluripotent stem (iPS) cells are provided. For example, a method of producing an iPS cell from a differentiated cell, which includes transforming the differentiated cell with a first vector comprising a nucleic acid sequence comprising a nucleic acid sequence encoding an Oct4, a nucleic acid sequence encoding a Sox2, and a nucleic acid sequence encoding a Klf4. Each of the nucleic acid sequences are separated from each other by a first and second viral 2A sequence. The method described can further comprise culturing the transformed cell under conditions that allow for the production of an iPS cell and isolating the cultured iPS cell.
FILED	Friday, May 25, 2012
APPL NO	13/480753
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2510/00 (20130101) C12N 2740/15043 (20130101) C12N 2800/30 (20130101)
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09175326 — Transglycosylation activity of glycosynthase mutants of an endo-beta-N-acetylglucosaminidase (endo-D) from streptococcus pneumoniae

US 09175326	Wang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
ASSIGNEE(S)	UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland)
INVENTOR(S)	Lai-Xi Wang (Ellicott City, Maryland)
ABSTRACT	The present invention provides for recombinant Endo-D and selected mutants that exhibit reduced hydrolysis activity and increased transglycosylation activity for the synthesis of glycoproteins wherein a desired sugar chain is added to a core fucosylated or nonfucosylated GlcNAc-protein acceptor by transglycosylation. Such recombinant Endo-D and selected mutants are useful for efficient glycosylation remodeling of IgG1-Fc domain.
FILED	Tuesday, February 05, 2013
APPL NO	13/759221
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/00 (20130101) C07K 16/2887 (20130101) C07K 2317/41 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Original (OR) Class Enzymes C12Y 302/01096 (20130101)
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09175338 — Methods for identifying nucleic acid modifications

US 09175338	Flusberg et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Benjamin Flusberg (Atlanta, Georgia); Jonas Korlach (Newark, California); Jeffrey Wegener (Cupertino, California); Tyson A. Clark (Menlo Park, California); Igor Vilfan (East Palo Alto, California); Andrey Kislyuk (San Ramon, California); Stephen Turner (Menlo Park, California); Jon Sorenson (Alameda, California); Kevin Travers (Menlo Park, California); Cheryl Heiner (San Mateo, California); Austin B. Tomaney (Burlingame, California); Patrick Marks (San Francisco, California); Jessica Lee (Cupertino, California); Lei Jia (Palo Alto, California); Dale Webster (San Mateo, California); John Lyle (Redwood Shores, California); Jeremiah Hanes (Redwood City, California); Joseph Puglisi (Stanford, California)
ASSIGNEE(S)	Pacific Biosciences of California, Inc. (Menlo Park, California)
INVENTOR(S)	Benjamin Flusberg (Atlanta, Georgia); Jonas Korlach (Newark, California); Jeffrey Wegener (Cupertino, California); Tyson A. Clark (Menlo Park, California); Igor Vilfan (East Palo Alto, California); Andrey Kislyuk (San Ramon, California); Stephen Turner (Menlo Park, California); Jon Sorenson (Alameda, California); Kevin Travers (Menlo Park, California); Cheryl Heiner (San Mateo, California); Austin B. Tomaney (Burlingame, California); Patrick Marks (San Francisco, California); Jessica Lee (Cupertino, California); Lei Jia (Palo Alto, California); Dale Webster (San Mateo, California); John Lyle (Redwood Shores, California); Jeremiah Hanes (Redwood City, California); Joseph Puglisi (Stanford, California)
ABSTRACT	Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
FILED	Friday, November 12, 2010
APPL NO	12/945767
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6858 (20130101) Original (OR) Class C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6858 (20130101) C12Q 1/6869 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2521/101 (20130101) C12Q 2525/117 (20130101) C12Q 2525/307 (20130101) C12Q 2527/113 (20130101) C12Q 2527/113 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101)
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09175340 — Reactivity-dependent and interaction-dependent PCR

US 09175340	Liu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	David R. Liu (Lexington, Massachusetts); David Gorin (Cambridge, Massachusetts); Adam Kamlet (Somerville, Massachusetts); Lynn M. McGregor (Cambridge, Massachusetts); Christoph E. Dumelin (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	David R. Liu (Lexington, Massachusetts); David Gorin (Cambridge, Massachusetts); Adam Kamlet (Somerville, Massachusetts); Lynn M. McGregor (Cambridge, Massachusetts); Christoph E. Dumelin (Cambridge, Massachusetts)
ABSTRACT	Methods, reagents, compositions, and kits for reactivity-dependent polymerase chain reaction (RD-PCR) and interaction-dependent polymerase chain reaction (ID-PCR) are provided herein. RD-PCR is a technique useful for determining whether a reactive moiety can form a covalent bond to a target reactive moiety, for example, in screening a library of candidate reactive moieties for reactivity with a target reactive moiety, and in identifying an enzyme substrate, for example, in protease substrate profiling. ID-PCR is a technique useful for determining whether a ligand can non-covalently bind to a target molecule, for example, in screening a library of candidate ligands for non-covalent interaction with a target molecule. RD-PCR and ID-PCR are also useful in detecting the presence of an analyte or an environmental condition.
FILED	Wednesday, October 13, 2010
APPL NO	13/505872
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1075 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 2525/301 (20130101) C12Q 2563/131 (20130101) C12Q 2563/179 (20130101)
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09175342 — Synthesis of cleavable fluorescent nucleotides as reversible terminators for DNA sequencing by synthesis

US 09175342	Ju et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	Jingyue Ju (Englewood Cliffs, New Jersey); Huanyan Cao (New York, New York); Zengmin Li (New York, New York); Qinglin Meng (Sunnyvale, California); Jia Guo (Mountain View, California); Shenglong Zhang (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Jingyue Ju (Englewood Cliffs, New Jersey); Huanyan Cao (New York, New York); Zengmin Li (New York, New York); Qinglin Meng (Sunnyvale, California); Jia Guo (Mountain View, California); Shenglong Zhang (New York, New York)
ABSTRACT	This invention provides novel azido linkers for deoxynucleotide analogues having a detectable marker attached thereto.
FILED	Thursday, July 25, 2013
APPL NO	13/951269
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/06 (20130101) C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 19/16 (20130101) C07H 19/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2525/301 (20130101) C12Q 2537/157 (20130101)
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09175348 — Identification of 5-methyl-C in nucleic acid templates

US 09175348	Korlach et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Pacific Biosciences of California, Inc. (Menlo Park, California); University of Chicago (Chicago, Illinois)
ASSIGNEE(S)	Pacific Biosciences of California, Inc. (Menlo Park, California)
INVENTOR(S)	Jonas Korlach (Newark, California); Chuan He (Chicago, Illinois); Tyson A. Clark (Menlo Park, California); Liang Zhang (Chicago, Illinois); Xingyu Lu (Chicago, Illinois)
ABSTRACT	A method for identifying a 5-MeC in a template nucleic is provided. The method comprises providing a template having 5-MeC, converting the 5-MeC into a further modification selected from 5-caC and 5-FC. The converted template is then sequenced, and a change in sequencing is detected that is indicative of the further modification, allowing for identifying the 5-MeC in the template nucleic acid.
FILED	Tuesday, April 23, 2013
APPL NO	13/868661
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2521/531 (20130101) C12Q 2521/531 (20130101) C12Q 2523/115 (20130101) C12Q 2523/115 (20130101) C12Q 2523/115 (20130101) C12Q 2523/115 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2525/307 (20130101) C12Q 2525/307 (20130101) C12Q 2527/113 (20130101) C12Q 2527/113 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) C12Q 2531/125 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101)
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09175349 — Methods of diagnosing endometriosis

US 09175349	Giudice
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Linda C. Giudice (Los Altos Hills, California)
ABSTRACT	The present invention provides biomarkers for the diagnosis and prognosis of endometriosis. Generally, the methods of this invention find use in diagnosing or for providing a prognosis for endometriosis by detecting the expression levels of biomarkers, which are differentially expressed (up- or down-regulated) in endometrial cells from a patient with endometriosis. Similarly, these markers can be used to diagnose reduced fertility in a patient with endometriosis or to provide a prognosis for a fertility trial in a patient suffering from endometriosis. The present invention also provides methods of identifying a compound for treating or preventing endometriosis. Finally, the present invention provides kits for the diagnosis or prognosis of endometriosis.
FILED	Tuesday, October 01, 2013
APPL NO	14/043616
ART UNIT	1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/364 (20130101)
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09175355 — Methods for determining the presence of antibodies blocking viral infection

US 09175355	Richman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Douglas Richman (La Jolla, California); Mary T. Wrin (Fremont, California); Susan Little (San Diego, California); Christos J. Petropoulos (Half Moon Bay, California); Neil T. Parkin (Belmont, California); Jeannette Whitcomb (San Mateo, California); Wei Huang (Foster City, California)
ASSIGNEE(S)	Monogram Biosciences, Inc. (South San Francisco, Colorado)
INVENTOR(S)	Douglas Richman (La Jolla, California); Mary T. Wrin (Fremont, California); Susan Little (San Diego, California); Christos J. Petropoulos (Half Moon Bay, California); Neil T. Parkin (Belmont, California); Jeannette Whitcomb (San Mateo, California); Wei Huang (Foster City, California)
ABSTRACT	The present invention provides a method for identifying whether a compound inhibits entry of a virus into a cell which comprises: (a) obtaining nucleic acid encoding a viral envelope protein from a patient infected by the virus; (b) co-transfecting into a first cell (i) the nucleic acid of step (a), and (ii) a viral expression vector which lacks a nucleic acid encoding an envelope protein, and which comprises an indicator nucleic acid which produces a detectable signal, such that the first cell produces viral particles comprising the envelope protein encoded by the nucleic acid obtained from the patient; (c) contacting the viral particles produced in step (b) with a second cell in the presence of the compound, wherein the second cell expresses a cell surface receptor to which the virus binds; (d) measuring the amount of signal produced by the second cell in order to determine the infectivity of the viral particles; and (e) comparing the amount of signal measured in step (d) with the amount of signal produced in the absence of the compound, wherein a reduced amount of signal measured in the presence of the compound indicates that the compound inhibits entry of the virus into the second cell.
FILED	Thursday, December 10, 2009
APPL NO	12/635539
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/005 (20130101) C07K 14/16 (20130101) C07K 14/162 (20130101) C07K 16/08 (20130101) C07K 16/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 33/5091 (20130101) G01N 33/56983 (20130101)
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09175944 — Durable single mode fiber probe with optimized reference reflectivity

US 09175944	Kang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Jin U. Kang (Ellicott City, Maryland); Xuan Liu (Baltimore, Maryland)
ABSTRACT	A probe for a common path optical coherence tomography system includes a sheath having a proximal end and a distal end and defining a lumen therein, a single mode optical fiber disposed within the lumen of the sheath such that a portion of the single mode optical fiber extends beyond the distal end of the sheath. The single mode optical fiber has an end face for transmitting and receiving light. The probe also includes a layer of hardened epoxy encasing the portion of the single mode optical fiber that extends beyond the distal end of the sheath except for the end face. The single mode optical fiber has an optical axis extending along a longitudinal direction of the single mode optical fiber. The hardened epoxy is polished at a non-orthogonal angle relative to the optical axis at the end face.
FILED	Monday, December 10, 2012
APPL NO	13/709958
ART UNIT	2883 — Optics
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 5/0066 (20130101) A61B 5/0073 (20130101) A61B 5/0084 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02052 (20130101) Original (OR) Class G01B 9/02091 (20130101) Optical Elements, Systems, or Apparatus G02B 6/06 (20130101) G02B 6/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/108 (20150115)
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09176059 — Optical analyte sensor

US 09176059	Lear et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Colorado State University Research Foundation (Fort Collins, Colorado)
ASSIGNEE(S)	COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
INVENTOR(S)	Kevin L. Lear (Fort Collins, Colorado); David S. Dandy (Fort Collins, Colorado); Matthew D. Stephens (Fort Collins, Colorado); Guangwei Yuan (Fort Collins, Colorado)
ABSTRACT	A waveguide sensor capable of direct, real-time detection and monitoring of analytes in the vicinity of the waveguide surface without requiring the tagging or labeling of the analyte, is described. Analytic and numerical calculations have predicted that by locally detecting either changes in the evanescent field or changes in the light coupled out of the waveguide as a result of the presence of the analyte, high detection sensitivity will be able to be achieved.
FILED	Wednesday, December 12, 2012
APPL NO	13/712425
ART UNIT	1677 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/552 (20130101) Original (OR) Class G01N 33/54373 (20130101)
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09176122 — Biomarkers for predicting response to immunosuppressive therapy

US 09176122	Burnette
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Pearlie K. Burnette (Tampa, Florida)
ASSIGNEE(S)	UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Pearlie K. Burnette (Tampa, Florida)
ABSTRACT	The subject invention concerns methods and materials for assessing a patient's likelihood of responsiveness to an immunosuppressive therapy. The subject invention is contemplated for use with patients having an autoimmune disorder. In an exemplified embodiment, the methods of the invention are used for assessing and/or treating a patient with MDS. In one embodiment, a method of the invention comprises analyzing T cells of a patient for dysregulation of CD4⁺ and/or CD8⁺ T cell subsets, and determining the patient's likelihood of responsiveness to IST based on the level of dysregulation of the patient's CD4⁺ and/or CD8⁺ T cell subsets. In one embodiment, an increased likelihood of patient responsiveness to IST is associated with an increased percentage of CD4⁺ and/or CD8⁺ effector memory T cells and/or terminal effector memory T cells for a patient. The subject invention also concerns methods for treating a patient with an autoimmune disorder, such as MDS. In one embodiment, a method of the invention comprises determining if a patient is likely to respond to IST, wherein said determination is made using a method of the present invention for assessing likelihood of responsiveness to IST; and if the patient is determined to be one likely to respond to IST, administering an effective regimen of IST to the patient.
FILED	Tuesday, March 24, 2009
APPL NO	12/933975
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5094 (20130101) Original (OR) Class G01N 33/6875 (20130101) G01N 33/57426 (20130101) G01N 2333/70564 (20130101) G01N 2333/70589 (20130101) G01N 2800/22 (20130101) G01N 2800/52 (20130101)
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09176135 — Method for predicting and preventing cardiovascular disease

US 09176135	Abranches et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	Jacqueline Abranches (Webster, New York); José A. Lemos (Webster, New York); Robert A. Burne (Gainesville, Florida)
ASSIGNEE(S)	University of Rochester (Rochester, New York); University of Florida (Gainesville, Florida)
INVENTOR(S)	Jacqueline Abranches (Webster, New York); José A. Lemos (Webster, New York); Robert A. Burne (Gainesville, Florida)
ABSTRACT	Disclosed are methods of identifying an individual having a predisposition to the development of a cardiovascular disease, and administering a suitable prophylactic agent to the identified individual to prevent disease. Methods of screening and identifying agents that inhibit bacterial collagen binding protein (CBP)-mediated cell invasion are also disclosed.
FILED	Monday, August 22, 2011
APPL NO	13/818405
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/689 (20130101) C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5085 (20130101) G01N 33/56955 (20130101) Original (OR) Class
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09176137 — Apparatus and methods for conducting assays and high throughput screening

US 09176137	Quake et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Stephen R. Quake (San Marino, California); Marc A. Unger (South San Francisco, California); Hou-Pu Chou (Sunnyvale, California); Todd A. Thorsen (Pasadena, California); Axel Scherer (Laguna Beach, California)
ABSTRACT	The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.
FILED	Monday, March 17, 2014
APPL NO	14/216740
ART UNIT	1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Separation B01D 57/02 (20130101) B01D 61/18 (20130101) B01D 61/28 (20130101) B01D 63/081 (20130101) B01D 63/088 (20130101) B01D 2313/08 (20130101) B01D 2313/90 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 5/0646 (20130101) B01F 5/0647 (20130101) B01F 7/00 (20130101) B01F 11/0071 (20130101) B01F 13/0059 (20130101) B01F 13/1013 (20130101) B01F 13/1022 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502738 (20130101) B01L 2200/0631 (20130101) B01L 2300/123 (20130101) B01L 2300/0645 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2300/1822 (20130101) B01L 2300/1827 (20130101) B01L 2400/0415 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 41/46 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/043 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0001 (20130101) F16K 99/0009 (20130101) F16K 99/0015 (20130201) F16K 99/0046 (20130101) F16K 99/0048 (20130101) F16K 99/0051 (20130101) F16K 99/0059 (20130101) F16K 2099/008 (20130101) F16K 2099/0074 (20130101) F16K 2099/0084 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) G01N 27/44791 (20130101) G01N 33/5005 (20130101) G01N 33/56966 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/11 (20150115) Y10T 436/25 (20150115) Y10T 436/2575 (20150115) Y10T 436/25375 (20150115) Y10T 436/117497 (20150115)
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09176147 — Detection of B-cell activating factor as a biomarker for antibody mediated rejection in transplant recipients

US 09176147	Bloom et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Debra D. Bloom (Sun Prairie, Wisconsin); Hans W. Sollinger (Madison, Wisconsin); Arjang Djamali (Cross Plains, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Debra D. Bloom (Sun Prairie, Wisconsin); Hans W. Sollinger (Madison, Wisconsin); Arjang Djamali (Cross Plains, Wisconsin)
ABSTRACT	The invention relates to methods, compositions, and kits for detection of biomarkers. In one embodiment, the invention relates to a method for detecting AMR biomarkers in a biological sample. In another embodiment, the invention relates to a method for detecting, monitoring, diagnosing and predicting antibody mediated rejection. In yet another embodiment, the invention relates to a method for monitoring a subject for antibody mediated rejection comprising detecting BAFF or a BAFF variant in a biological sample. In still another embodiment, the invention relates to a kit for detecting BAFF in a urine sample.
FILED	Monday, October 25, 2010
APPL NO	13/501671
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 14/52 (20130101) C07K 14/475 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/245 (20130101)
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09176148 — Method for the early detection of renal disease using proteomics

US 09176148	Devarajan
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S)	Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S)	Prasad Devarajan (Cincinnati, Ohio)
ABSTRACT	A method for the detection of an early biomarker for assessing a change in renal status in a mammalian subject following a renal event. The method typically includes the steps of (a) providing a body fluid sample obtained from a mammalian subject; (b) analyzing the molecular weight of the proteins in the sample using proteome analysis; and (c) identifying the presence of a protein in the sample selected from the group consisting of a 6.4 kDa protein, a 28.5 kDa protein, a 33 kDa protein, a 44 kDa protein, a 67 kDa protein, and combinations thereof. The presence of one of these proteins can serve as an early biomarker for assessing a change in renal status. The levels of these proteins can be compared to predetermined levels, and thus provide a determination of the subject's renal status. The invention also includes a method of assessing the administration of aprotinin during cardio-pulmonary bypass surgery and provides for methods where the level of the 6.4 kDa biomarker in the subject's urine directs a caregiver's therapeutic decision regarding the intra-operative administration of aprotinin.
FILED	Thursday, October 03, 2013
APPL NO	14/044953
ART UNIT	1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) G01N 33/6848 (20130101) G01N 33/6851 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/226 (20130101) G01N 2800/347 (20130101)
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09176211 — Method for quantitatively mapping myocardial contractile function with magnetic resonance based multiparametric strain analysis

US 09176211	Cupps et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Brian P. Cupps (Manchester, Missouri); Michael K. Pasque (Town and Country, Missouri)
ASSIGNEE(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S)	Brian P. Cupps (Manchester, Missouri); Michael K. Pasque (Town and Country, Missouri)
ABSTRACT	The strain at different locations in a subject's heart is determined by acquiring a series of MR images using a tagging pulse sequence (SPAMM) that produces a grid of lines in the reconstructed images. Circumferential strain, longitudinal strain, and the minimum principal strain angle, are all calculated at locations in the heart. These raw strain values are normalized by comparing them with corresponding values in a stored reference heart model. The normalized values at each location are combined to form a composite multiparametric strain index that is indicative of myocardial contractile function and these values are employed to modulate the color at corresponding locations in an anatomical image of the subject's heart.
FILED	Thursday, January 08, 2009
APPL NO	12/350444
ART UNIT	3777 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/56333 (20130101) Original (OR) Class
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09176504 — High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation

US 09176504	Chiou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Aeronautics and Space Administration (NASA) National Science Foundation (NSF)
APPLICANT(S)	Pei-Yu Chiou (Los Angeles, California); Ting-Hsiang S. Wu (Los Angeles, California); Sung-Yong Park (Thousand Oaks, California); Michael A. Teitell (Tarzana, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Pei-Yu Chiou (Los Angeles, California); Ting-Hsiang S. Wu (Los Angeles, California); Sung-Yong Park (Thousand Oaks, California); Michael A. Teitell (Tarzana, California)
ABSTRACT	Methods and devices for the formation of droplets of a first fluid in a second fluid and the encapsulation of particles or cells within such droplets are disclosed. Impetus for droplet formation is provided by the creation of a transient bubble, which may be induced using a pulsed laser. Droplet volume and the frequency at which droplets are formed can be controlled by modulation of the pulsed laser. The disclosed methods and devices are particularly suitable for use in microfluidic devices.
FILED	Thursday, February 09, 2012
APPL NO	13/370196
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 21/64 (20130101) G01N 29/2418 (20130101) G01N 2015/1481 (20130101) G01N 2291/02433 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 11/13 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/2496 (20150401)
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09177374 — Model-based processing of image data

US 09177374	Stayman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Joseph Webster Stayman (Baltimore, Maryland); Jeffrey H. Siewerdsen (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Joseph Webster Stayman (Baltimore, Maryland); Jeffrey H. Siewerdsen (Baltimore, Maryland)
ABSTRACT	An imaging system for processing image data of an object containing a component. The imaging system includes an imaging device arranged to obtain image data and a processor. The processor is adapted to receive the image data from the imaging device, obtain a component model for the component, obtain an imaging device model for the imaging device, construct an unconstrained objective function based on the component model and the imaging device model, and construct a model of the object containing the component based on the unconstrained objective function and the image data, and a display device adapted to display an image for the object containing the component based on the model.
FILED	Monday, March 26, 2012
APPL NO	14/006592
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/0046 (20130101) G06T 11/006 (20130101) G06T 2207/10081 (20130101) G06T 2207/30052 (20130101) G06T 2211/424 (20130101)
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Department of Defense (DOD)

09173384 — Surgically implanted micro-platforms and microsystems in arthropods and methods based thereon

US 09173384	Lal et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF)
APPLICANT(S)	Amit Lal (Ithaca, New York); John Ewer (Valparaiso, Chile); Ayesa Kaur (Ithaca, New York); Alper Bozkurt (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Amit Lal (Ithaca, New York); John Ewer (Valparaiso, Chile); Ayesa Kaur (Ithaca, New York); Alper Bozkurt (Ithaca, New York)
ABSTRACT	A method is provided for producing an arthropod comprising introducing a microsystem such as a MEMS device into an immature arthropod under conditions that result in producing an adult arthropod with a functional microsystem permanently attached to its body. A method is also provided for producing a robotic apparatus. The method can comprise introducing a microsystem such as a MEMS device into an immature arthropod under conditions that result in producing a robotic apparatus with the microsystem permanently attached to the body of the adult arthropod.
FILED	Tuesday, December 11, 2007
APPL NO	12/518847
ART UNIT	3766 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/033 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/372 (20130101) A61N 1/3605 (20130101)
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09173582 — Adaptive performance trainer

US 09173582	Popovic et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Djordje Popovic (Oceanside, California); Gene Davis (Oceanside, California); Chris Berka (Carlsbad, California); Adrienne Behneman (Carlsbad, California); Giby Raphael (Carlsbad, California)
ASSIGNEE(S)	ADVANCED BRAIN MONITORING, INC. (Carlsbad, Georgia)
INVENTOR(S)	Djordje Popovic (Oceanside, California); Gene Davis (Oceanside, California); Chris Berka (Carlsbad, California); Adrienne Behneman (Carlsbad, California); Giby Raphael (Carlsbad, California)
ABSTRACT	Techniques for accelerating training through optimization of the psychophysiological state of the trainee are provided. These techniques include an adaptive performance training system configured to acquire, analyzed, display, and translate data that reflects the psychophysiological state of the user, including the electrical activity of the brain (EEG), the heart (EKG), the musculature (EMG), respiration and other parameters that characterize the state of the user in real-time. The system includes a plurality of feedback mechanisms for providing visual, auditory, and/or tactile feedback based on the current psychophysiological state of the user and for facilitating moving the user toward a goal psychophysiological state for performing a particular task and for optimizing performance of that task.
FILED	Friday, April 23, 2010
APPL NO	12/766322
ART UNIT	3769 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/11 (20130101) A61B 5/16 (20130101) A61B 5/021 (20130101) A61B 5/0402 (20130101) Original (OR) Class A61B 5/0476 (20130101) A61B 5/486 (20130101) A61B 5/0488 (20130101) A61B 5/0816 (20130101) A61B 5/02405 (20130101)
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09173817 — In situ forming hemostatic foam implants

US 09173817	Sharma et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Upma Sharma (Somerville, Massachusetts); Irina Gitlin (San Francisco, California); Gregory T. Zugates (Chelmsford, Massachusetts); Adam Rago (Falmouth, Massachusetts); Parisa Zamiri (Brookline, Massachusetts); Rany Busold (Medford, Massachusetts); Toby Freyman (Waltham, Massachusetts); Robert J. Caulkins (Watertown, Massachusetts); Quynh P. Pham (Methuen, Massachusetts); Changcheng You (Burlington, Massachusetts); Jeffrey D. Carbeck (Belmont, Massachusetts)
ASSIGNEE(S)	Arsenal Medical, Inc. (Watertown, Massachusetts)
INVENTOR(S)	Upma Sharma (Somerville, Massachusetts); Irina Gitlin (San Francisco, California); Gregory T. Zugates (Chelmsford, Massachusetts); Adam Rago (Falmouth, Massachusetts); Parisa Zamiri (Brookline, Massachusetts); Rany Busold (Medford, Massachusetts); Toby Freyman (Waltham, Massachusetts); Robert J. Caulkins (Watertown, Massachusetts); Quynh P. Pham (Methuen, Massachusetts); Changcheng You (Burlington, Massachusetts); Jeffrey D. Carbeck (Belmont, Massachusetts)
ABSTRACT	Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
FILED	Friday, August 12, 2011
APPL NO	13/209020
ART UNIT	3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/2093 (20130101) Original (OR) Class
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09173871 — Oxazole and thiazole compounds as beta-catenin modulators and uses thereof

US 09173871	Dasgupta et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Ramanuj Dasgupta (New York, New York); Foster Gonsalves (Brooklyn, New York); Susan Katherine Logan (New York, New York); Eugine Lee (New York, New York)
ASSIGNEE(S)	New York University (New York, New York)
INVENTOR(S)	Ramanuj Dasgupta (New York, New York); Foster Gonsalves (Brooklyn, New York); Susan Katherine Logan (New York, New York); Eugine Lee (New York, New York)
ABSTRACT	A series of oxazole and thiazole compounds are shown herein to be small molecule inhibitors of the Wnt pathway that specifically target the activity of the stabilized pool of β-catenin. Oxazole and thiazole compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, cancer, and others.
FILED	Tuesday, April 17, 2012
APPL NO	13/448737
ART UNIT	1627 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/422 (20130101) Original (OR) Class A61K 31/426 (20130101) A61K 31/427 (20130101) Heterocyclic Compounds C07D 263/32 (20130101) C07D 413/12 (20130101)
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09173908 — Methods for modulating immune responses

US 09173908	Banas et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Army Medical Research Acquisition Activity (USAMRAA)
APPLICANT(S)	Stemnion, Inc. (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	STEMNION, INC. (Pittsburgh, Pennsylvania)
INVENTOR(S)	Richard A. Banas (Turtle Creek, Pennsylvania); Catherine J. Trumpower (Pittsburgh, Pennsylvania); Vivienne S. Marshall (San Antonio, Texas)
ABSTRACT	The invention is directed to novel methods for modulating inflammatory and/or immune responses. Such methods utilize compositions comprising extraembryonic cells (herein referred to as EE cells) including but not limited to extraembryonic HLA-G positive cells (herein referred to as EHP cells) and amnion-derived multipotent progenitor cells (herein referred to as AMP cells); compositions comprising expanded EE cell populations, and/or cell lysates and/or conditioned media derived therefrom, alone or in combination with each other and/or in combination with various extracellular matrices and/or devices and/or other suitable active agents.
FILED	Thursday, February 05, 2015
APPL NO	14/614911
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/50 (20130101) Original (OR) Class A61K 38/21 (20130101) A61K 38/1709 (20130101) A61K 39/001 (20130101) A61K 39/3955 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) C12N 2502/025 (20130101)
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09173950 — Vitamin D-ghrelin conjugates

US 09173950	Soliman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Extend Biosciences, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	Extend Biosciences, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Howard P. Sard (Arlington, Massachusetts); Mukkanti Amere (Woburn, Massachusetts)
ABSTRACT	The invention provides carriers that enhance the absorption, half-life or bioavailability of Ghrelin peptides. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties.
FILED	Saturday, November 15, 2014
APPL NO	14/542581
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) A61K 47/4813 (20130101) A61K 47/48107 (20130101) A61K 47/48215 (20130101) Original (OR) Class
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09173971 — Simple adhesive coacervates and methods of making and using thereof

US 09173971	Stewart
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Russell J. Stewart (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Russell J. Stewart (Salt Lake City, Utah)
ABSTRACT	Described herein is the synthesis of adhesive from simple adhesive coacervates and their uses thereof. The adhesives are produced by (a) preparing a solution comprising (1) a polyelectrolyte, wherein the polyelectrolyte comprises a polyanion or polycation but not a combination thereof, the polyeletrolyte comprises at least one crosslinking group, and (2) a sufficient amount of a complimentary counterion to produce a simple adhesive coacervate; and (b) crosslinking the simple adhesive coacervate to produce the adhesive. The adhesives have numerous medical and non-medical applications.
FILED	Saturday, November 12, 2011
APPL NO	13/295061
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/001 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/2852 (20150115)
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09174186 — Supercrystalline colloidal particles and method of production

US 09174186	Cao et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Y. Charles Cao (Gainesville, Florida); Jiaqi Zhuang (Gainesville, Florida); Huimeng Wu (Gainesville, Florida); Yongan Yang (Golden, Colorado)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	Y. Charles Cao (Gainesville, Florida); Jiaqi Zhuang (Gainesville, Florida); Huimeng Wu (Gainesville, Florida); Yongan Yang (Golden, Colorado)
ABSTRACT	The present invention concerns size- and shape-controlled, colloidal superparticles (SPs) and methods for synthesizing the same. Ligand-functionalized nanoparticles such as nonpolar-solvent-dispersible nanoparticles, are used, and the solvophobic interactions can be controlled. Advantageously, supercrystalline SPs having a superlattice structure, such as a face-centered cubic structure, can be produced. Further, the methods of the invention can provide SPs that self-assemble and are monodisperse. The SPs can be doped with organic dyes and further assembled into more complex structures.
FILED	Friday, August 15, 2008
APPL NO	12/672447
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0026 (20130101) Original (OR) Class B01J 13/0043 (20130101)
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09174422 — Apparatus for manufacturing microconduit networks formed by electrospinning techniques

US 09174422	Guenthner et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	SECRETARY OF THE DEPARTMENT OF THE NAVY (China Lake, California)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Andrew J. Guenthner (Lancaster, California); David M Hess (Redondo Beach, California)
ABSTRACT	A microconduit network structure and methods for making the same. One aspect of the invention relates to a microconduit network structure, including: a solid or semi-solid matrix having at least one interconnected web of filaments formed within the matrix; and wherein at least one interconnected web of filaments having diameters of about 10 nm to about 1 mm.
FILED	Friday, December 14, 2012
APPL NO	13/714892
ART UNIT	1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/18 (20130101) B29C 67/20 (20130101) B29C 67/202 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 33/00 (20130101) Original (OR) Class Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101)
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09174889 — Metal hydride nanoparticles

US 09174889	Epshteyn et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Albert Epshteyn (College Park, Maryland); Andrew P Purdy (Alexandria, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Albert Epshteyn (College Park, Maryland); Andrew P Purdy (Alexandria, Virginia)
ABSTRACT	A nanoparticle of a decomposition product of a transition metal aluminum hydride compound, a transition metal borohydride compound, or a transition metal gallium hydride compound. A process of: reacting a transition metal salt with an aluminum hydride compound, a borohydride compound, or a gallium hydride compound to produce one or more of the nanoparticles. The reaction occurs in solution while being sonicated at a temperature at which the metal hydride compound decomposes. A process of: reacting a nanoparticle with a compound containing at least two hydroxyl groups to form a coating having multi-dentate metal-alkoxides.
FILED	Wednesday, November 26, 2008
APPL NO	12/323617
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0062 (20130101) B22F 9/24 (20130101) B22F 9/24 (20130101) B22F 9/24 (20130101) B22F 2003/248 (20130101) B22F 2202/01 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/32 (20130101) Original (OR) Class
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09174909 — Two-stage, acid-catalyzed conversion of carbohydrates into levulinic acid

US 09174909	Runge
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Troy Runge (Waunakee, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Troy Runge (Waunakee, Wisconsin)
ABSTRACT	A method of producing levulinic acid from biomass is described. The method includes two acid treatment steps: first, treating biomass with a first aqueous acidic solution at a pH, for a time, and temperature such that at least a portion of pentosans contained within the biomass is extracted from the biomass, to yield pentosan-extracted biomass; second, treating the pentosan-extracted biomass with a second aqueous acidic solution at a pH, for a time, and a temperature, such that at least a portion of hexosans contained within the pentosan-extracted biomass are converted to levulinic acid.
FILED	Thursday, February 02, 2012
APPL NO	13/364472
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 51/00 (20130101) Original (OR) Class C07C 51/00 (20130101) C07C 59/185 (20130101)
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09174951 — Glucose transporter inhibitors

US 09174951	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	The Ohio State University Research Foundation (Columbus, Ohio)
ASSIGNEE(S)	OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
INVENTOR(S)	Ching-Shih Chen (Upper Arlington, Ohio); Dasheng Wang (Dublin, Ohio); Samuel K. Kulp (Hillard, Ohio)
ABSTRACT	Thiazolidinedione compounds and pharmaceutically acceptable salts thereof are described. The compounds can be used in methods of treating cancer in a subject by administering to the subject a therapeutically effective amount of the compound. The compounds can also be used in methods of inhibiting glucose uptake in a cell by contacting the cell with the compound.
FILED	Thursday, March 28, 2013
APPL NO	14/386127
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 277/34 (20130101) Original (OR) Class
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09175137 — Method for producing cyanurate networks via inductive heating of silica-coated magnetic nanoparticles

US 09175137	Sahagun et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Christopher Sahagun (Lancaster, California); Andrew Guenthner (Lancaster, California); Joseph Mabry (Lancaster, California)
ABSTRACT	A method for curing a macromolecular cyanurate network. The method of curing includes suspending a plurality of functionalized silica-coated magnetic nanoparticles in a resin mixture, which includes cyanate ester monomers, cyanate ester oligomers, or both. After a static magnetic field is applied to the plurality of functionalized silica-coated magnetic nanoparticles in the resin mixture, an alternating electromagnetic field (having frequency ranging from about 1 kHz to about 10 MHz) is imposed for a cure time.
FILED	Monday, November 25, 2013
APPL NO	14/089316
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0655 (20130101) Original (OR) Class
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09175153 — Cellulose hydrogel compositions and contact lenses for corneal applications

US 09175153	Trexler et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Congressionally Directed Medical Research Programs (CDMRP) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S)	Morgana M. Trexler (Baltimore, Maryland); Jenna L. Graham (Columbia, Maryland); Jennifer L. Breidenich (Atlanta, Georgia); Jeffrey P. Maranchi (Clarkburg, Maryland); Julia B. Patrone (Ellicott City, Maryland); Marcia W. Patchan (Columbia, Maryland); Jennifer H. Elisseeff (Baltimore, Maryland); Xiomara Calderon-Colon (Laurel, Maryland)
ABSTRACT	The present invention provides cellulose hydrogels having one or more of the following properties: high water content, high transparency, high oxygen permeability, high biocompatibility, high tensile strength and desirable thermal stability. The present invention further provides a process for preparing a cellulose hydrogel comprising (i) a step of activating cellulose, in which the activating step comprises contacting the cellulose with a solvent to activate the cellulose for a time duration from about 2 hours to about 30 hours; (ii) substantially dissolving the activated cellulose to form a solution; and (iii) gelling the solution to form a gel, in which the gelling step comprises allowing the solution to gel in an environment comprising a relative humidity from about 30% to about 80% at 35° C.
FILED	Thursday, September 11, 2014
APPL NO	14/483637
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/145 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00096 (20130101) Polysaccharides; Derivatives Thereof C08B 1/003 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2301/02 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) Original (OR) Class C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/02 (20130101) C08L 1/08 (20130101) C08L 29/04 (20130101) C08L 33/10 (20130101) C08L 33/20 (20130101) C08L 33/20 (20130101) C08L 33/26 (20130101) C08L 33/26 (20130101) C08L 33/066 (20130101) C08L 39/06 (20130101) C08L 71/02 (20130101) C08L 83/04 (20130101) C08L 101/14 (20130101) C08L 2205/02 (20130101) C08L 2205/16 (20130101) Optical Elements, Systems, or Apparatus G02B 1/043 (20130101) G02B 1/043 (20130101) G02B 1/043 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 7/049 (20130101)
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09175422 — Polymer-micelle complex as an aid to electrospinning

US 09175422	Nagarajan et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Ramanathan Nagarajan (Newton, Massachusetts); Christopher P. Drew (Clinton, Massachusetts); Charlene M. Mello (Rochester, Massachusetts)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Ramanathan Nagarajan (Newton, Massachusetts); Christopher P. Drew (Clinton, Massachusetts); Charlene M. Mello (Rochester, Massachusetts)
ABSTRACT	A polymer-micelle complex suitable for use as an aid to preparing fibers, particularly nanofibers, by electrospinning. The polymer-micelle complex may be designed to impart viscosity, surface tension and conductivity properties optimal for electrospinning. By incorporating the complex as a secondary ingredient, one may electrospin sparingly soluble or low molecular weight polymers. Moreover, the polymer-micelle complex can be used as a generic carrier for preparing fibers incorporating other desired materials, such as rigid or globular (hard-to-spin) polymers, enzymes, cells, viral particles and nanoparticles.
FILED	Monday, November 05, 2007
APPL NO	11/998981
ART UNIT	1789 — Miscellaneous Articles, Stock Material
CURRENT CPC	Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/298 (20150115)
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09175877 — Two-dimensional Fresnel solar energy concentration system

US 09175877	Olsen
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Randall B. Olsen (Carlsbad, California)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Randall B. Olsen (Carlsbad, California)
ABSTRACT	The present invention provides a solar energy concentrating reflection system comprising multiple arrays of solar reflectors arranged adjacent to one another on a generally planar support structure where each of the reflector arrays configured into a first Fresnel array in a first dimension. Each of the first Fresnel array of reflectors are in turn arrayed and supported in a support frame in a configuration of second Fresnel arrays in a second dimension such that solar energy from the sun is reflected and concentrated to a predetermined focal line. A solar receiver is disposed in the focal line of the configured solar reflectors such that the first and second Fresnel arrays uniformly reflect and concentrate solar energy from the sun onto the solar receiver within the first and second dimensions with a uniform solar intensity profile.
FILED	Monday, February 13, 2012
APPL NO	13/371792
ART UNIT	3743 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Producing or Use of Heat Not Otherwise Provided For F24J 2/12 (20130101) Original (OR) Class F24J 2/54 (20130101) F24J 2/085 (20130101) F24J 2002/5458 (20130101)
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09175914 — Remote weapons charging handle adapter

US 09175914	Bird et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	James Bird (Succasunna, New Jersey); James Giacchi (Warren, New Jersey); Russell Jones, III (Newton, New Jersey); Matthew Moeller (Randolph, New Jersey); David Bound (Rockaway, New Jersey)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	James Bird (Succasunna, New Jersey); James Giacchi (Warren, New Jersey); Russell Jones, III (Newton, New Jersey); Matthew Moeller (Randolph, New Jersey); David Bound (Rockaway, New Jersey)
ABSTRACT	A remotely-operated gun is mounted in a cradle having a linear actuator for charging the gun. A charging adapter that is fixed to the linear actuator enables different types of guns to be charged. The charging adapter is easily configured to accommodate different gun types.
FILED	Monday, September 22, 2014
APPL NO	14/492533
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 3/72 (20130101) Original (OR) Class
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09175930 — Adaptive electronic camouflage

US 09175930	Pezeshkian et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Narek Pezeshkian (Glendale, California); Hobart R. Everett (San Diego, California); Joseph D. Neff (San Diego, California)
ASSIGNEE(S)	The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Narek Pezeshkian (Glendale, California); Hobart R. Everett (San Diego, California); Joseph D. Neff (San Diego, California)
ABSTRACT	In one preferred embodiment, the present invention provides an adaptive electronic camouflage platform comprising electronic paper panels conformed to the exterior surface of the vehicle; one or more cameras for sampling images of the local environment surrounding the platform; and a processor for analyzing the sampled images, generating synthesized camouflage patterns corresponding to the sampled images and controlling the display of the synthesized camouflage patterns on the electronic paper panels.
FILED	Thursday, March 29, 2012
APPL NO	13/434174
ART UNIT	2486 — Recording and Compression
CURRENT CPC	Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 3/00 (20130101) Original (OR) Class
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09175933 — Simple low-cost hand-held landmine neutralization device

US 09175933	Patel
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S)	Divyakant L. Patel (Woodbridge, Virginia)
ABSTRACT	A low-cost, reliable and easy to use kit for neutralizing surface exposed landmine and unexploded ordnance for humanitarian demining is provided. The kit contains a liquid fuel and a solid/soluble fuel. Both fuels are premeasured in separate, sealed containers. The addition of a small quantity of solid/soluble fuel into the liquid creates an explosive. The resulting mixture is capable of detonating with a standard No. 8 blasting cap. The solid/soluble fuel can be in the form of a powder, tablet, or its saturated solution in water. The solid/soluble fuel is hexamethylenetetramine. The liquid fuel, nitromethane, is provided in premeasured quantities. User is provided instructions for choosing the appropriate quantity of liquid fuel, the corresponding solid/soluble fuel required, the method of mixing, placement and detonation of the kits. Also disclosed is a simple wooden stand to hold the bottle of explosive in place. A special fuel, liquid 2-ethylhexylnitrate, is provided to desensitize the mixed and sensitized explosive.
FILED	Friday, February 21, 2014
APPL NO	14/186162
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/002 (20130101) C06B 25/00 (20130101) C06B 47/00 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/12 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/10 (20130101)
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09175937 — Gasless ignition system and method for making same

US 09175937	Reeves et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Robert V. Reeves (Albuquerque, New Mexico); Steven F. Son (West Lafayette, Indiana); Lori J. Groven (Clarks Hill, Indiana); Alexander S. Mukasyan (Granger, Indiana)
ASSIGNEE(S)	Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S)	Robert V. Reeves (Albuquerque, New Mexico); Steven F. Son (West Lafayette, Indiana); Lori J. Groven (Clarks Hill, Indiana); Alexander S. Mukasyan (Granger, Indiana)
ABSTRACT	A fuze includes a housing having a first end and an opposing second end and defining an elongate channel extending between the first and second ends; and a mechanically activated reactive material comprising at least first and second elements disposed within the channel.
FILED	Monday, April 09, 2012
APPL NO	13/442853
ART UNIT	3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/11 (20130101) F42B 3/16 (20130101) Original (OR) Class
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09176010 — Miniaturized thermocouple scanner system

US 09176010	Reich et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Alton Reich (Huntsville, Alabama); James Shaw (Sterling, Connecticut)
ASSIGNEE(S)	Streamline Automation, LLC (Huntsville, Alabama)
INVENTOR(S)	Alton Reich (Huntsville, Alabama); James Shaw (Sterling, Connecticut)
ABSTRACT	An apparatus and method for measuring, collecting, and processing the temperatures of a number of hot junctions in a thermocouple sensor array simultaneously comprises means for measuring the temperature of one or more reference junctions and means for collecting, processing, storing, and transmitting data collected from an array of thermocouple temperature sensors. The measured temperature(s) of the one or more reference junctions is used to correct the measured voltage in each of a plurality of thermocouple circuits to obtain accurate hot junction temperature measurements. The apparatus and method are particularly useful for collecting and processing temperature data from various locations within engines such as turbine, rocket, and internal combustion engines.
FILED	Tuesday, August 30, 2011
APPL NO	13/819718
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/026 (20130101) G01K 7/02 (20130101) Original (OR) Class G01K 7/13 (20130101) G01K 7/021 (20130101) G01K 2205/00 (20130101)
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09176015 — Point load sensor

US 09176015	Sefranek
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Jeffrey K. Sefranek (Charlestown, Rhode Island)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Jeffrey K. Sefranek (Charlestown, Rhode Island)
ABSTRACT	A point load sensor measures compressive forces exerted on the outside of a ring in diametric compression irrespective of the direction of application of the force. The sensor consists of a ring with strain gauges placed in a configuration to measure the circumferential strain at two positions on the ring ninety degrees apart resulting from bending of the ring as the ring is loaded in diametric compression. The two measurements are corrected and combined to recover the compressive force on the ring. A method for calibrating and resolving the compressive force does not require the angle of loading or sensor orientation as an input, thus allowing resolution irrespective of the direction of the compressive force.
FILED	Wednesday, February 08, 2012
APPL NO	13/368714
ART UNIT	2865 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/22 (20130101) Original (OR) Class
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09176114 — Cell culture model for acquired chemoresistance of chronic myelogenous leukemia and related methods for identifying agents to overcome resistance

US 09176114	Chen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	CITY OF HOPE (Duarte, California)
ASSIGNEE(S)	CITY OF HOPE (Duarte, California)
INVENTOR(S)	WenYong Chen (Temple City, California); Ravi Bhatia (Duarte, California); Leila Su (Diamond Bar, California); Yate-Ching Yuan (Arcadia, California)
ABSTRACT	A method of generating a chronic myelogenic leukemia (CML) acquired chemoresistant culture model is provided. Such a method may comprise providing a naïve blast crisis CML cell line; administering/contacting the cell line with a mutation-inducing dose of imatinib; maintaining a culture of the treated cell line for a period of time until the treated cell line relapses and repopulates the culture; and determining the repopulated cell culture is a CML acquired chemoresistant cell line by detecting a BCR-ABL mutation, wherein the acquired chemoresistance is achieved by a BCR-ABL mutation.
FILED	Wednesday, June 19, 2013
APPL NO	13/922141
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class G01N 33/5047 (20130101) G01N 2333/98 (20130101) G01N 2333/91142 (20130101) G01N 2500/10 (20130101)
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09176117 — Macrophage hazardous material detection

US 09176117	Silver
FUNDED BY	Department of Defense (DOD) Defense Threat Reduction Agency (DTRA)
APPLICANT(S)	Robert B. Silver (Syracuse, New York)
ASSIGNEE(S)	Defense Threat Reduction Agency, Dept. of Defense, United States Government (Washington, District of Columbia)
INVENTOR(S)	Robert B. Silver (Syracuse, New York)
ABSTRACT	Sentinel Cells, respond quickly and differentially to and among various high explosives (e.g., RDX, PETN, HMX, TNT, TNG), taggant (DMDNB), and bacteria, as well as volatiles of commercial C4, Semtex 1A, and military C4. These effects are observable within 5 minutes of exposure, indicate profound biological effects in exposed cells, and are distinctly different from responses to bacteria (e.g., E. coli, mycoplasma, lipopolysaccharide from E. coli, etc.). Quantitative and mechanistic analysis of the observations indicate that the mechanisms that give rise to these responses invoke different subsets of biochemical reactions. The mechanism within the exposed Sentinel Cells is also used in canine olfactory cells (e.g., bomb dogs). The nature of the explosives-induced biological effects provide for a cell based explosives detection system (i.e., a cellular dog nose), as well as a tool for the study of biological effects of energetic materials on humans.
FILED	Thursday, June 14, 2012
APPL NO	13/523501
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0645 (20130101) C12N 2503/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/5055 (20130101) Original (OR) Class G01N 2333/4603 (20130101)
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09176206 — Effective-inductance-change based magnetic particle sensing

US 09176206	Wang et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	Hua Wang (Pasadena, California); Seyed Ali Hajimiri (Pasadena, California); Yan Chen (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Hua Wang (Pasadena, California); Seyed Ali Hajimiri (Pasadena, California); Yan Chen (Pasadena, California)
ABSTRACT	The invention relates to an integrated measurement system to detect a quantity of magnetic particles in a sample. The measurement system includes a substrate. An electromagnetic (EM) structure disposed on the surface of the substrate is configured to receive a sample including the magnetic particles in proximity thereof. The integrated measurement system also includes an electrical current generator disposed on the surface of the substrate which is electro-magnetically coupled to the EM structure. The electrical current generator is configured to cause an electrical current to flow in the EM structure. The integrated measurement system also includes an effective inductance sensor disposed on the surface of the substrate which is configured to measure a selected one of an effective inductance and a change in effective inductance. The invention also relates to a method to determine the number of and/or the locations of the magnetic particles in a sample.
FILED	Friday, March 06, 2009
APPL NO	12/399603
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/1269 (20130101) Original (OR) Class
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09176218 — Gain projection geo-location systems and methods

US 09176218	Fehling et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Greg Fehling (Nashua, New Hampshire); Peter Dusaitis (Manchester, New Hampshire); Tyler Robinson (Merrimack, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	Greg Fehling (Nashua, New Hampshire); Peter Dusaitis (Manchester, New Hampshire); Tyler Robinson (Merrimack, New Hampshire)
ABSTRACT	A system and method for estimating the geographic location of an RF emitter which involves spatially filtering and receiving RF signals through use of a beamforming antenna array having multiple overlapping beams; detecting and measuring the time-of-arrival and amplitude of signals which are received in each beam through use of multiple synchronized receivers; identifying simultaneous detections of the same emitter which have occurred in adjacent beams; projecting the associated beamformed antenna gain patterns onto the underlying terrain for all instances in which there was a simultaneous detection in adjacent beams; weighting and accumulating all projections to form a Maximum Likelihood Surface (MLS); and finally, estimating the location of the emitter through analysis of the resulting MLS.
FILED	Wednesday, September 12, 2012
APPL NO	13/611781
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/38 (20130101) G01S 3/46 (20130101) G01S 5/06 (20130101) G01S 5/0205 (20130101) G01S 5/0278 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 3/26 (20130101) Transmission H04B 7/086 (20130101) H04B 7/0891 (20130101)
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09176263 — Optical micro-sensor

US 09176263	Zickler et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Todd Zickler (Cambridge, Massachusetts); Sanjeev Jagannatha Koppal (Cambridge, Massachusetts); Geoffrey Louis Barrows (Washington, District of Columbia); Ioannis Gkioulekas (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Centeye Incorporated (Washington, District of Columbia)
INVENTOR(S)	Todd Zickler (Cambridge, Massachusetts); Sanjeev Jagannatha Koppal (Cambridge, Massachusetts); Geoffrey Louis Barrows (Washington, District of Columbia); Ioannis Gkioulekas (Cambridge, Massachusetts)
ABSTRACT	Briefly, embodiments of an optical micro-sensor are described.
FILED	Wednesday, April 06, 2011
APPL NO	13/081490
ART UNIT	2878 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Original (OR) Class
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09176278 — Generating broadband spectral power in multimode optical fibers

US 09176278	Kelly et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	David P. Kelly (Nashua, New Hampshire); Peter A. Ketteridge (Amherst, New Hampshire); Daniel J. Creeden (Nashua, New Hampshire); Benjamin R. Johnson (Nottingham, New Hampshire)
ASSIGNEE(S)	BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S)	David P. Kelly (Nashua, New Hampshire); Peter A. Ketteridge (Amherst, New Hampshire); Daniel J. Creeden (Nashua, New Hampshire); Benjamin R. Johnson (Nottingham, New Hampshire)
ABSTRACT	A broadband spectral power generator in a multimode optical fiber utilizes a standard multimode fiber that is coiled. A plate is placed on the coiled fiber and a force is applied to compresses the coiled fiber and thereby increase the interactions between the compressed windings and induce modal mixing and birefringence in the fiber. In addition, the compression causes additional non-linear processes to be excited and occur in the compressed fiber coil to generate more broadband light. This allows for better “mixing” of the spatial beam in the multimode fiber coil and allows for the various modes to overlap. The multimode fiber coil is made of silica, silicate, germinate, phosphate, fluoride, chalcogenide, or telluride. The compressed coiled fiber may be driven by a laser providing more than one wavelength output and this greatly increases the amount of nonlinear mixing in the fiber for a greatly enhanced spectral coverage.
FILED	Wednesday, August 22, 2012
APPL NO	13/994429
ART UNIT	2883 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) G02B 6/268 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/383 (20130101) G02F 2001/3528 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/102 (20130101) H01S 3/302 (20130101) H01S 3/06704 (20130101)
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09176280 — Optical reflector based on a directional coupler and a coupled optical loop

US 09176280	Li et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Oracle International Corporation (Redwood City, California)
ASSIGNEE(S)	ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California)
INVENTOR(S)	Guoliang Li (San Diego, California); Xuezhe Zheng (San Diego, California); Ying L. Luo (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	An optical device includes an optical reflector based on a coupled-loopback optical waveguide. In particular, an input port, an output port and an optical loop in arms of the optical reflector are optically coupled to a directional coupler. The directional coupler evanescently couples an optical signal between the arms. For example, the directional coupler may include: a multimode interference coupler and/or a Mach-Zehnder Interferometer (MZI). Moreover, destructive interference during the evanescent coupling determines the reflection and transmission power coefficients of the optical reflector.
FILED	Monday, October 21, 2013
APPL NO	14/059282
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/293 (20130101) G02B 6/29331 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/225 (20130101) G02F 2001/212 (20130101) G02F 2001/217 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/18 (20130101) H01S 5/141 (20130101) H01S 5/02252 (20130101)
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09176291 — Grating coupler for inter-chip optical coupling

US 09176291	Li et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Guoliang Li (San Diego, California); Ying L. Luo (San Diego, California); Xuezhe Zheng (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ASSIGNEE(S)	ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California)
INVENTOR(S)	Guoliang Li (San Diego, California); Ying L. Luo (San Diego, California); Xuezhe Zheng (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California)
ABSTRACT	A photonic integrated circuit (PIC) that includes an optical source that provides an optical signal having a wavelength is described. This optical source includes a reflecting layer, a bottom cladding layer, an active layer (such as a III-V semiconductor) having a bandgap wavelength that exceeds that of silicon, and a top cladding layer. Moreover, an optical coupler (such as a grating coupler) that couples the optical signal out of a plane of the active layer is included in a region of the active layer. In this region, the top cladding layer is absent. Furthermore, in an adjacent region, the top cladding layer includes an inverse taper so that the top cladding layer is tapered down from a width distal from the region. In conjunction with the optical coupler, the inverse taper may facilitate low-loss optical coupling of the optical signal between the PIC and another PIC.
FILED	Friday, August 17, 2012
APPL NO	13/588242
ART UNIT	2874 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 6/34 (20130101) G02B 6/124 (20130101) G02B 6/1228 (20130101) G02B 6/1347 (20130101) G02B 6/4296 (20130101) Original (OR) Class G02B 2006/12188 (20130101)
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09176774 — Workflow control of reservations and regular jobs using a flexible job scheduler

US 09176774	Druyan et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Alexander Druyan (New York, New York); Wei Li (Beijing, China PRC); Kailash N. Marthi (Poughkeepsie, New York); Yun T. Xiang (Beijing, China PRC); Linda C. Cham (Poughkeepsie, New York)
ABSTRACT	A scheduler receives flexible reservation requests for scheduling in a computing environment comprising consumable resources. The flexible reservation request specifies a duration and a required resource. The consumable resources comprise machine resources and floating resources. The scheduler creates a flexible job for the flexible reservation request and places the flexible job in a prioritized job queue for scheduling, wherein the flexible job is prioritizes relative to at least one regular job in the prioritized job queue. The scheduler adds a reservation set to a waiting state for the flexible reservation request. The scheduler, responsive to detecting the flexible job positioned in the prioritized job queue for scheduling next and detecting a selection of consumable resources available to match the at least one required resource for the duration, transfers the selection of consumable resources to the reservation and sets the reservation to an active state.
FILED	Friday, April 05, 2013
APPL NO	13/857357
ART UNIT	2196 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/4881 (20130101) Original (OR) Class G06F 9/5038 (20130101) G06F 2209/506 (20130101) G06F 2209/5014 (20130101) G06F 2209/5021 (20130101)
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09176876 — Selective cache-to-cache lateral castouts

US 09176876	Guthrie et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Guy L. Guthrie (Austin, Texas); William J. Starke (Round Rock, Texas); Jeffrey A. Stuecheli (Austin, Texas); Derek E. Williams (Austin, Texas); Thomas R. Puzak (Ridgefield, Connecticut)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Guy L. Guthrie (Austin, Texas); William J. Starke (Round Rock, Texas); Jeffrey A. Stuecheli (Austin, Texas); Derek E. Williams (Austin, Texas); Thomas R. Puzak (Ridgefield, Connecticut)
ABSTRACT	A data processing system includes first and second processing units and a system memory. The first processing unit has first upper and first lower level caches, and the second processing unit has second upper and lower level caches. In response to a data request, a victim cache line to be castout from the first lower level cache is selected, and the first lower level cache selects between performing a lateral castout (LCO) of the victim cache line to the second lower level cache and a castout of the victim cache line to the system memory based upon a confidence indicator associated with the victim cache line. In response to selecting an LCO, the first processing unit issues an LCO command on the interconnect fabric and removes the victim cache line from the first lower level cache, and the second lower level cache holds the victim cache line.
FILED	Thursday, April 12, 2012
APPL NO	13/445646
ART UNIT	2139 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 12/12 (20130101) G06F 12/0811 (20130101) Original (OR) Class
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09176993 — Efficiently identifying images, videos, songs or documents most relevant to the user using binary search trees on attributes for guiding relevance feedback

US 09176993	Grauman et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)	Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S)	Kristen Grauman (Austin, Texas); Adriana Kovashka (Austin, Texas)
ABSTRACT	A method, system and computer program product for efficiently identifying images, videos, audio files or documents relevant to a user using binary search trees in attribute space for guiding relevance feedback. A binary tree is constructed for each relative attribute of interest. A “pivot exemplar” (at a node of the binary tree) is set for each relative attribute's binary tree as corresponding to the database image, video, audio file or document with a median relative attribute value among that subtree's child examples. A pivot exemplar out of the available current pivot exemplars that has the highest expected information gain is selected to be provided to the user. Comparative attribute feedback is then received from the user regarding whether a degree of the attribute in the user's target image, video, audio file or document is more, less or equal with the attribute displayed in the selected pivot exemplar.
FILED	Tuesday, August 13, 2013
APPL NO	13/965677
ART UNIT	2161 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/30274 (20130101) Original (OR) Class
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09177130 — Facial feature detection

US 09177130	Nechyba et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Research, Development and Engineering Command (RDECOM) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	Michael Christian Nechyba (Pittsburgh, Pennsylvania); Michael Andrew Sipe (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Google Inc. (Mountain View, California)
INVENTOR(S)	Michael Christian Nechyba (Pittsburgh, Pennsylvania); Michael Andrew Sipe (Pittsburgh, Pennsylvania)
ABSTRACT	An example method includes capturing, by a camera of a computing device, an image including at least a face of a user, calculating a face template of the face of the user in the image, and analyzing the face template to determine whether the face includes at least one of a removable facial feature that decreases a level of distinctiveness between two faces and a non-removable facial feature that decreases a level of distinctiveness between two faces. When the face includes the removable facial feature, the method further includes outputting a notification for the user to remove the removable facial feature. When the face includes the non-removable facial feature, the method further includes adjusting a first similarity score threshold to a second similarity score threshold.
FILED	Tuesday, January 08, 2013
APPL NO	13/736760
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 21/32 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00221 (20130101) G06K 9/6217 (20130101)
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09177133 — Multi-function smart communication card

US 09177133	Toth et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	William Toth (Ocean, New Jersey); Stanley Fong (Hazlet, New Jersey); Todd Lutton (New Windsor, Maryland); Uday Shenvi (Columbia, Maryland); Ghanshyam Dave (Marlton, New Jersey); Matthew Lazzaro (Churchville, Maryland)
ABSTRACT	Various embodiments are described that relate to a smart card. When not connected to an external system, such as a laptop computer, the smart card can be configured to power itself. Thus, various functions can be practiced on the smart card in absence of connection to the external system. Example functions of the smart card can include user identification and authorization. In addition, the smart card can be configured to distinguish between different users and provide different access levels to different users and/or difference access to containers resident within the smart card. This can be done prior to when the smart card is connected to the external system.
FILED	Monday, July 14, 2014
APPL NO	14/330051
ART UNIT	2887 — Optics
CURRENT CPC	Electric Digital Data Processing G06F 21/32 (20130101) G06F 21/34 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0701 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0853 (20130101) H04L 63/0861 (20130101)
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09177153 — Verifying integrity and guaranteeing execution of code on untrusted computer platform

US 09177153	Perrig et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Adrian Perrig (Pittsburgh, Pennsylvania); Pradeep Khosla (Pittsburgh, Pennsylvania); Arvind Seshadri (Pittsburgh, Pennsylvania); Mark Luk (Fremont, California); Leendert van Doorn (Valhalla, New York)
ASSIGNEE(S)	Carnegie Mellon University (Pittsburg, Pennsylvania)
INVENTOR(S)	Adrian Perrig (Pittsburgh, Pennsylvania); Pradeep Khosla (Pittsburgh, Pennsylvania); Arvind Seshadri (Pittsburgh, Pennsylvania); Mark Luk (Fremont, California); Leendert van Doorn (Valhalla, New York)
ABSTRACT	A method, system, and apparatus for verifying integrity and execution state of an untrusted computer. In one embodiment, the method includes placing a verification function in memory on the untrusted computer; invoking the verification function from a trusted computer; determining a checksum value over memory containing both the verification function and the execution state of a processor and hardware on the untrusted computer; sending the checksum value to the trusted computer; determining at the trusted computer whether the checksum value is correct; and determining at the trusted computer whether the checksum value is received within an expected time period.
FILED	Tuesday, October 10, 2006
APPL NO	11/545924
ART UNIT	2439 — Cryptography and Security
CURRENT CPC	Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class
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09177185 — Passive wireless sensors for chemical and biological agents and wireless systems including the passive wireless sensors

US 09177185	Patterson
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Research Laboratory (AFRL)
APPLICANT(S)	University of Dayton (Dayton, Ohio)
ASSIGNEE(S)	University of Dayton (Dayton, Ohio)
INVENTOR(S)	Mark Alan Patterson (Beavercreek, Ohio)
ABSTRACT	Wireless sensors for detection of an analyte may include a sensor receiving antenna configured to receive interrogation pulses having an interrogation frequency, a DC converter, a relaxation oscillator circuit electrically, and a sensor transmitting antenna. The relaxation oscillator circuit may include a capacitance element that defines a response-pulse frequency of the wireless sensor. The capacitance element may include an interdigitated capacitor coated with a detection layer of a functional material having a dielectric constant that defines the dielectric constant of the interdigitated capacitor. This dielectric constant changes when the functional material is exposed to the analyte, thereby changing the response-pulse frequency of the relaxation oscillator circuit to an analyte-exposure frequency indicative of the exposure of the functional material to the analyte. Wireless systems for detecting an analyte may include a wireless sensor that communicates with an interrogation module.
FILED	Wednesday, July 24, 2013
APPL NO	13/949907
ART UNIT	2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0031 (20130101) G01N 2291/0255 (20130101) G01N 2291/0256 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Original (OR) Class G06K 19/0716 (20130101)
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09177228 — Method and system for fusion of fast surprise and motion-based saliency for finding objects of interest in dynamic scenes

US 09177228	Khosla et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Deepak Khosla (Camarillo, California); David J. Huber (Calabasas, California); Kyungnam Kim (Oak Park, California)
ABSTRACT	Described is a system for object detection from dynamic visual imagery. Dynamic visual input obtained from a stationary sensor is processed by a surprise-based module. The surprise-based module detects a stationary object in a scene to generate surprise scores. The dynamic visual input is also processed by a motion-based saliency module which detects foreground in the scene to generate motion scores. The surprise scores and motion scores are fused into a single score, and the single score is used to determine the presence of an object of interest.
FILED	Thursday, January 17, 2013
APPL NO	13/743742
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6289 (20130101) Original (OR) Class
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09177259 — Systems and methods for recognizing and reacting to spatiotemporal patterns

US 09177259	Levchuk
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Georgiy Levchuk (South Grafton, Massachusetts)
ASSIGNEE(S)	Aptima Inc. (Woburn, Massachusetts)
INVENTOR(S)	Georgiy Levchuk (South Grafton, Massachusetts)
ABSTRACT	Embodiments of the disclosed systems and methods comprise systems and methods for recognizing actions of an object and matching those actions with expected patterns of actions. In some embodiments, the methods recognize actions using statistical classifiers and aggregate data about locomotions, actions, and interactions of the object to infer patterns of that object using a pattern recognition algorithm. In some embodiments, the systems and methods are further able to select responses to recognized patterns and learn patterns over time.
FILED	Tuesday, November 29, 2011
APPL NO	13/306023
ART UNIT	2122 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 99/005 (20130101) Original (OR) Class
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09177318 — Method and apparatus for customizing conversation agents based on user characteristics using a relevance score for automatic statements, and a response prediction function

US 09177318	Shen et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S)	PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California)
INVENTOR(S)	Jianqiang Shen (Santa Clara, California); Oliver Brdiczka (Mountain View, California)
ABSTRACT	A conversation-simulating system facilitates simulating an intelligent conversation with a human user. During operation, the system can receive a user-statement from the user during a simulated conversation, and generates a set of automatic-statements that each responds to the user-statement. The system then determines a set of behavior-characteristics for the user, and computes relevance scores for the automatic-statements based on the behavior-characteristics. Each relevance score indicates an outcome quality that the user is likely to perceive for the automatic-statement as a response to the user-statement. The system selects an automatic-statement that has a highest relevance score from the set of automatic-statements, and provides the selected automatic-statement to the user.
FILED	Monday, April 22, 2013
APPL NO	13/867991
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 3/006 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/01 (20130101) Original (OR) Class
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09177466 — Advanced battery early warning and monitoring system

US 09177466	Xie et al.
FUNDED BY	Department of Defense (DOD)
APPLICANT(S)	INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana)
ASSIGNEE(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	Jian Xie (Carmel, Indiana); Jie Chen (Carmel, Indiana); Lingxi Li (Zionsville, Indiana); Yaobin Chen (Carmel, Indiana)
ABSTRACT	Systems, apparatuses and methods for detecting internal cell faults using online and real-time sensing techniques, and providing an accurate and reliable early warning for the incoming failure of battery cells hours or days prior to failure. A system is configured to perform real-time and direct measurement of battery cell parameters of temperature, voltage, and AC impedance through online sensing. These parameters may be simultaneously processed using advanced probabilistic and/or fuzzy logic-based algorithms to provide an early warning for the incoming failure of battery cells in a battery pack. This technology may safeguard the LIB battery packs while allowing them to operate at or near 100% capacity in both transportation and stationary applications.
FILED	Monday, December 31, 2012
APPL NO	13/731788
ART UNIT	2682 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3606 (20130101) G01R 31/3651 (20130101) G01R 31/3675 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 29/181 (20130101) Original (OR) Class
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09177547 — System and method for processing speech to identify keywords or other information

US 09177547	Kintzley et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Keith Kintzley (Severna Park, Maryland); Aren Jansen (Ellicott City, Maryland); Hynek Hermansky (Baltimore, Maryland); Kenneth Church (Croton-on-Hudson, New York)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Keith Kintzley (Severna Park, Maryland); Aren Jansen (Ellicott City, Maryland); Hynek Hermansky (Baltimore, Maryland); Kenneth Church (Croton-on-Hudson, New York)
ABSTRACT	A system and method are provided for performing speech processing. A system includes an audio detection system configured to receive a signal including speech and a memory having stored therein a database of keyword models forming an ensemble of filters associated with each keyword in the database. A processor is configured to receive the signal including speech from the audio detection system, decompose the signal including speech into a sparse set of phonetic impulses, and access the database of keywords and convolve the sparse set of phonetic impulses with the ensemble of filters. The processor is further configured to identify keywords within the signal including speech based a result of the convolution and control operation the electronic system based on the keywords identified.
FILED	Tuesday, June 25, 2013
APPL NO	13/926659
ART UNIT	2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/14 (20130101) Original (OR) Class G10L 15/22 (20130101) G10L 2015/085 (20130101) G10L 2015/088 (20130101)
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09177685 — High power, broadband terahertz, photoconductive antennas with chaotic shape electrodes

US 09177685	Wu et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Dong Ho Wu (Olney, Maryland); Benjamin Graber (Washington, District of Columbia); Christopher Kim (Springfield, Virginia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Dong Ho Wu (Olney, Maryland); Benjamin Graber (Washington, District of Columbia); Christopher Kim (Springfield, Virginia)
ABSTRACT	A photoconductive antenna is described that includes a substrate that includes a pair of trenches. Furthermore, a pair of non-parallel electrodes, which can be designed with a chaotic electrode geometry, can each be deposited in one of the trenches, and can be configured to produce chaotic trajectories of incoherent electric currents. Finally, an insulation layer, which can be either a physical electrical insulation layer or an air gap, can be included between each of the pair of non-parallel electrodes and the trench walls. Overall, the thickness of the substrate, the thickness of the trenches, and the thickness of the non-parallel electrodes can each be optimized to produce a coherent terahertz beam.
FILED	Wednesday, May 06, 2015
APPL NO	14/705022
ART UNIT	2881 — Optics
CURRENT CPC	Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/02 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 1/02 (20130101)
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09177723 — High voltage high current transmission line

US 09177723	Appleton et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Contracting Command (ACC) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	BAE Systems Land and Armaments, L.P. (Santa Clara, California)
ASSIGNEE(S)	BAE Systems Land and Armaments L.P. (Santa Clara, California)
INVENTOR(S)	Randall J. Appleton (West St. Paul, Minnesota); Timothy J. Doering (Anoka, Minnesota)
ABSTRACT	A high voltage high current transmission line for transmitting high voltage high current energy in the 10 kV and 200,000 A range from a power source to an end item to which the power is delivered. The high voltage high current transmission line includes two generally parallel configured conductive plates with an overlapping dielectric layering configuration. Each of the conductive plates are encompassed by a first dielectric material, both of the conductive plates encompassed by a second dielectric material, and the conductive plates are encompassed by an outer dielectric sheathing. The dielectric layering configuration may also include a dielectric material applied to the edges of the conductive plates. At one or both ends of the high voltage high current transmission line, a plug assembly may be provided for connecting to the power source and/or the discharge device. The high voltage high current transmission line may also include an exposed conductive plate surface with a staggered configuration such that the exposed surfaces of the conductive plates do not overlap.
FILED	Friday, March 15, 2013
APPL NO	13/834125
ART UNIT	2847 — Electrical Circuits and Systems
CURRENT CPC	Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/228 (20130101) Original (OR) Class Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/50 (20130101) H01R 13/53 (20130101) H01R 13/64 (20130101) H01R 13/5216 (20130101) H01R 2201/26 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115)
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09178096 — Luminescent solar concentrator

US 09178096	Ziegler et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Leidos, Inc. (Reston, Virginia)
ASSIGNEE(S)	Leidos, Inc. (Reston, Virginia)
INVENTOR(S)	John Paul Ziegler (San Diego, California); Howard Walter Walker (San Diego, California); Richard Holmes Griffey (Vista, California); Newell Convers Wyeth (Oakton, Virginia)
ABSTRACT	A stacked luminescent solar concentrator includes two separate absorption/emission cells, each having a layer of luminophore-type material, wherein a top layer is a high band gap layer comprised of quantum dots in polymer, wherein the quantum dots are engineered so as to absorb a significant percentage of photons above bandgap. The bottom layer is a lower band gap layer comprised of quantum dots in polymer, wherein the quantum dots in the second layer are engineered so as to absorb photons not absorbed in the top layer, thus increasing total percentage of absorbed photons. Photovoltaic cells are located below the layers at the bottom of the cells or at the edges of the cells. The sides and lower surfaces of the cells may include reflective surfaces as discussed further herein. Reflection losses from the top surface thereof may be minimized using a broadband anti-reflective coating (AR) on the surface.
FILED	Wednesday, October 15, 2014
APPL NO	14/515134
ART UNIT	1758 — Optics
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) Original (OR) Class H01L 31/056 (20141201) H01L 31/02168 (20130101) H01L 31/035218 (20130101)
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09178129 — Graphene-based films in sensor applications

US 09178129	Lee et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Trustees of the Stevens Institute of Technology (Hoboken, New Jersey)
ASSIGNEE(S)	THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey)
INVENTOR(S)	Woo Young Lee (Ridgewood, New Jersey); Linh Tung Le (New York, New York); De Kong (Wood-Ridge, New Jersey)
ABSTRACT	An environmental sensor comprises a graphene thin-film as an environmentally responsive material. Such graphene films exhibit negative temperature coefficients (NTC), resulting in rapid decreases in electrical resistance as temperature increases, as well as a much faster response time than any other NTC material reported in the literature. The graphene film is also mechanically stable under bending, and, therefore, can be adapted for use in a mechanical sensor or pressure sensor, because the electrical resistance of the graphene film changes upon deflection and/or changes in pressure. The electrical resistance of the graphene film also increases in response to increases in environmental humidity. The electrical resistance changes of the graphene film can also be used as a sensing mechanism for changes in chemical and biological parameters in the environment of the sensor.
FILED	Monday, October 14, 2013
APPL NO	14/053232
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/22 (20130101) G01K 15/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48 (20130101) Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 2047/025 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 37/00 (20130101) Original (OR) Class H01L 41/02 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178131 — Ferroelectric nanoshell devices

US 09178131	Spanier et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Jonathan E Spanier (Bala Cynwyd, Pennsylvania); Stephen S Nonnenmann (Philadelphia, Pennsylvania); Oren David Leaffer (Philadelphia, Pennsylvania)
ABSTRACT	Disclosed herein are nanoscale devices comprising one or more ferroelectric nanoshells characterized as having an extreme curvature in at least one spatial dimension. Also disclosed are ferroelectric field effect transistors and metal ferroelectric metal capacitors comprising one or more ferroelectric nanoshells. Methods for controlling spontaneous ferroelectric polarization in nanoshell devices are also disclosed.
FILED	Monday, February 10, 2014
APPL NO	14/176315
ART UNIT	2895 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/008 (20130101) H01G 4/33 (20130101) H01G 4/1209 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/28291 (20130101) H01L 27/0214 (20130101) H01L 28/40 (20130101) H01L 29/068 (20130101) H01L 29/0665 (20130101) H01L 29/0673 (20130101) H01L 29/775 (20130101) H01L 29/6684 (20130101) H01L 29/66977 (20130101) H01L 29/78391 (20130101) H01L 43/02 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

09178248 — Solid-state electrolytes for rechargeable lithium batteries

US 09178248	Scanlon, Jr. et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
ASSIGNEE(S)	The United Stated of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S)	Lawrence G Scanlon, Jr. (Fairborn, Ohio); Joseph P Fellner (Kettering, Ohio); William A. Feld (Beavercreek, Ohio); Leah R. Lucente (Beavercreek, Ohio); Jacob W. Lawson (Springfield, Ohio); Andrew M. Beauchamp (Lancaster, California); David W Firsich (Dayton, Ohio)
ABSTRACT	A lithium ion battery cell. The lithium ion battery cell includes a lithium-based anode, a cathode, and a solid-state electrolyte positioned between the lithium-based anode and the cathode. The cathode comprises an alkylammonium cation lithium phthalocyanine anion complex. The solid-state electrolyte comprises an alkoxyalkylammonium cation lithium phthalocyanine anion complex.
FILED	Wednesday, May 13, 2015
APPL NO	14/710948
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/30 (20130101) H01M 4/60 (20130101) H01M 4/134 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178255 — Lithium-air cells incorporating solid electrolytes having enhanced ionic transport and catalytic activity

US 09178255	Kumar et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Binod Kumar (Dayton, Ohio); Jitendra Kumar (Dayton, Ohio)
ASSIGNEE(S)	University of Dayton (Dayton, Ohio)
INVENTOR(S)	Binod Kumar (Dayton, Ohio); Jitendra Kumar (Dayton, Ohio)
ABSTRACT	Liquid-free lithium-air cells are provided which incorporate a solid electrolyte having enhanced ionic transport and catalytic activity. The solid electrolyte is positioned between a lithium anode and an oxygen cathode, and comprises a glass-ceramic and/or a polymer-ceramic electrolyte including a dielectric additive.
FILED	Wednesday, June 17, 2009
APPL NO	12/486444
ART UNIT	1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/447 (20130101) C04B 2235/3203 (20130101) C04B 2235/3217 (20130101) C04B 2235/3287 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 4/382 (20130101) H01M 4/8605 (20130101) H01M 4/8621 (20130101) H01M 4/8652 (20130101) H01M 4/9016 (20130101) H01M 10/056 (20130101) H01M 10/0562 (20130101) H01M 10/0565 (20130101) H01M 12/08 (20130101) Original (OR) Class H01M 2300/0068 (20130101) H01M 2300/0082 (20130101) H01M 2300/0091 (20130101) H01M 2300/0094 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178329 — Laser design

US 09178329	Wechsler et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Department of the Army (DOA) Missile Defense Agency (MDA)
APPLICANT(S)	Barry A. Wechsler (Kinnelon, New Jersey); Michael P. Scripsick (Lafayette, New Jersey); David S. Sumida (Marina del Rey, California); Thomas G. Crow (Las Cruces, New Mexico)
ASSIGNEE(S)
INVENTOR(S)	Barry A. Wechsler (Kinnelon, New Jersey); Michael P. Scripsick (Lafayette, New Jersey); David S. Sumida (Marina del Rey, California); Thomas G. Crow (Las Cruces, New Mexico)
ABSTRACT	A laser gain element including an undoped layer of a monoclinic double tungstate (MDT) crystal, and a method of forming a laser gain element are provided. The laser gain element includes a layer of doped MDT crystal adjacent to the undoped layer, the doped MDT layer including a pre-selected concentration of rare earth ions. The layer of doped MDT crystal has an absorption peak at a first wavelength and an emission peak at a second wavelength longer than the first wavelength; and the layer of doped MDT crystal has a fluorescence emission with a weighted average at a third wavelength shorter than the first wavelength. A laser resonator cavity formed with a plurality of composite gain elements as above is also provided.
FILED	Friday, May 11, 2012
APPL NO	13/470081
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 19/12 (20130101) C30B 29/32 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0408 (20130101) H01S 3/0602 (20130101) Original (OR) Class H01S 3/0604 (20130101) H01S 3/0612 (20130101) H01S 3/0941 (20130101) H01S 3/1618 (20130101) H01S 3/1675 (20130101) H01S 3/09408 (20130101) H01S 3/094084 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178518 — Sub-threshold FPGA and related circuits and methods thereof

US 09178518	Calhoun et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Benton H. Calhoun (Charlottesville, Virginia); Joseph F. Ryan (Portland, Oregon)
ASSIGNEE(S)	University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S)	Benton H. Calhoun (Charlottesville, Virginia); Joseph F. Ryan (Portland, Oregon)
ABSTRACT	A sub-V_TFPGA uses a low swing, dual-V_DDinterconnect scheme to reduce FPGA area per LUT, delay at a constant energy, and energy at a constant delay relative to a conventional design at low voltage. These improvements are made possible by a custom asynchronous sense amp, a separated voltage for memory cells, and an improved passgate interconnect to optimize routing delay with low energy overhead. This sub-threshold FPGA design enables energy efficient and cost effective configurable logic for a wide variety of ULP applications.
FILED	Thursday, March 17, 2011
APPL NO	13/635350
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 19/17744 (20130101) Original (OR) Class H03K 19/17784 (20130101) H03K 19/17788 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178544 — Parameter offset estimation through use of a secondary signal collected from multiple sensors

US 09178544	Su
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Army (Washingon, District of Columbia)
INVENTOR(S)	Wei Su (Bel Air, Maryland)
ABSTRACT	Various embodiments associated with estimating a parameter offset for editions of a signal of interest through use of a secondary signal are described. A plurality of distributed asynchronous sensors can capture editions of a signal of interest as well as editions of a secondary signal. The secondary signal can be much stronger than the signal of interest. Since individual sensors capture the signal of interest editions and the secondary editions, offset calculated for one can be used for the other. With the secondary signal being stronger than the signal of interest, the offset of the editions of the signal of interest can be estimated. Once the offset is estimated for the secondary editions, the offset can be used for the signal of interest editions. After the offset is used to align the signal of interest editions, the signal of interest editions can be combined and further processing can occur.
FILED	Thursday, March 07, 2013
APPL NO	13/788520
ART UNIT	2632 — Digital Communications
CURRENT CPC	Transmission H04B 1/1027 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 27/2649 (20130101) Wireless Communication Networks H04W 4/005 (20130101)
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09178936 — Selected alert delivery in a distributed processing system

US 09178936	Carey et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	James E. Carey (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	James E. Carey (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota)
ABSTRACT	Methods, apparatuses, and computer program products for selected alert delivery in a distributed processing system are provided. Embodiments include receiving a plurality of events from one or more event producing components of the distributed processing system; creating, by an incident analyzer, in dependence upon the events a truth space representing events that make one or more conditional event processing rules true, the truth space including a set of truth points, each truth point including a set of events and a set of event locations; creating, by the incident analyzer, in dependence upon the truth space one or more alerts; and sending, by the incident analyzer, the alerts to at least one component of the distributed processing system.
FILED	Tuesday, October 18, 2011
APPL NO	13/275530
ART UNIT	2449 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 11/0709 (20130101) G06F 11/0748 (20130101) G06F 11/0781 (20130101) G06F 11/3006 (20130101) G06F 11/3055 (20130101) G06F 11/3058 (20130101) G06F 11/3072 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0618 (20130101) H04L 67/10 (20130101) Original (OR) Class H04L 67/18 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178937 — Selected alert delivery in a distributed processing system

US 09178937	Carey et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	James E. Carey (Rochester, Minnesota); Philip J. Sanders (Rochester, Minnesota)
ABSTRACT	Methods, apparatuses, and computer program products for selected alert delivery in a distributed processing system are provided. Embodiments include receiving a plurality of events from one or more event producing components of the distributed processing system; creating, by an incident analyzer, in dependence upon the events a truth space representing events that make one or more conditional event processing rules true, the truth space including a set of truth points, each truth point including a set of events and a set of event locations; creating, by the incident analyzer, in dependence upon the truth space one or more alerts; and sending, by the incident analyzer, the alerts to at least one component of the distributed processing system.
FILED	Friday, December 07, 2012
APPL NO	13/708061
ART UNIT	2449 — Computer Networks
CURRENT CPC	Electric Digital Data Processing G06F 11/0709 (20130101) G06F 11/0748 (20130101) G06F 11/0781 (20130101) G06F 11/3006 (20130101) G06F 11/3055 (20130101) G06F 11/3058 (20130101) G06F 11/3072 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0618 (20130101) H04L 67/10 (20130101) Original (OR) Class H04L 67/18 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09179202 — Multiple-frequency signal classification through use of a second-order statistic

US 09179202	Su
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Wei Su (Bel Air, Maryland)
ABSTRACT	A multi-frequency (also known as multiple-frequency) signal, such as a dual-tone signal, can be a repeating signal that indicates a character designated on a keypad. The signal can be processed such that the character is identifiable. This processing can include using first and second-order statistics of the signal to determine an estimated average frequency of the signal. A table can be accessed that lists individual characters of the keypad and specific average frequency values can be associated with the individual characters. The specific average frequency value that is closest to the estimated average frequency can be identified and the character associated with this closest specific average frequency value can be appointed as the character indicated by the signal. Thus, the multi-frequency signal can be classified as communicating the appointed character.
FILED	Monday, September 16, 2013
APPL NO	14/027433
ART UNIT	2652 — Videophones and Telephonic Communications
CURRENT CPC	Selecting H04Q 1/45 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

Department of Energy (DOE)

09174213 — Passive chip-based droplet sorting

US 09174213	Beer et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the University of California (Oakland, California)
INVENTOR(S)	Neil Reginald Beer (Pleasanton, California); Abraham P. Lee (Irvine, California); Andrew C. Hatch (Irvine, California); Jeffrey S. Fisher (San Diego, California)
ABSTRACT	An apparatus for passive sorting of microdroplets including a main flow channel, a flow stream of microdroplets in the main flow channel wherein the microdroplets have substantially the same diameter and wherein the flow stream of microdroplets includes first microdroplets having a first degree of stiffness and second microdroplets having a second degree of stiffness wherein the second degree of stiffness is different than the first degree of stiffness. A second flow channel is connected to the main flow channel for the second microdroplets having a second degree of stiffness. A separator separates the second microdroplets having a second degree of stiffness from the first microdroplets and directs the second microdroplets having a second degree of stiffness into the second flow channel.
FILED	Tuesday, February 24, 2015
APPL NO	14/629930
ART UNIT	1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/0652 (20130101) B01L 2300/168 (20130101) B01L 2300/0864 (20130101) B01L 2300/0877 (20130101) B01L 2400/084 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 2015/1081 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09174355 — Incorporation of metal nanoparticles into wood substrate and methods

US 09174355	Rector et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Kirk D. Rector (Santa Cruz, New Mexico); Marcel Lucas (Pullman, Washington)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Kirk D. Rector (Santa Cruz, New Mexico); Marcel Lucas (Pullman, Washington)
ABSTRACT	Metal nanoparticles were incorporated into wood. Ionic liquids were used to expand the wood cell wall structure for nanoparticle incorporation into the cell wall structure. Nanoparticles of elemental gold or silver were found to be effective surface enhanced Raman spectroscopy (SERS) imaging contrast or sensing agents. Nanoparticles of elemental iron were found to be efficient microwave absorbers and caused localized heating for disrupting the integrity of the lignocellulosic matrix. Controls suggest that the localized heating around the iron nanoparticles reduces losses of cellulose in the form of water, volatiles and CO₂. The ionic liquid is needed during the incorporation process at room temperature. The use of small amounts of ionic liquid combined with the absence of an ionic liquid purification step and a lower energy and water use are expected to reduce costs in an up-scaled pretreatment process.
FILED	Wednesday, April 20, 2011
APPL NO	13/642060
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Processes, Apparatus or Selection of Substances for Impregnating, Staining, Dyeing, Bleaching of Wood or Similar Materials, or Treating of Wood or Similar Materials With Permeant Liquids, Not Otherwise Provided for; Chemical or Physical Treatment of Cork, Cane, Reed, Straw or Similar Materials B27K 3/007 (20130101) Original (OR) Class B27K 3/16 (20130101) B27K 3/0221 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 17/63 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 33/46 (20130101) G01N 33/587 (20130101) G01N 33/54373 (20130101)
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09174844 — Calcium looping process for high purity hydrogen production integrated with capture of carbon dioxide, sulfur and halides

US 09174844	Ramkumar et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	The Ohio State University Research Foundation (Columbus, Ohio)
ASSIGNEE(S)
INVENTOR(S)	Shwetha Ramkumar (Columbus, Ohio); Liang-Shih Fan (Columbus, Ohio)
ABSTRACT	A process for producing hydrogen comprising the steps of: (i) gasifying a fuel into a raw synthesis gas comprising CO, hydrogen, steam, sulfur and halide contaminants in the form of H₂S, COS, and HX, wherein X is a halide; (ii) passing the raw synthesis gas through a water gas shift reactor (WGSR) into which CaO and steam are injected, the CaO reacting with the shifted gas to remove CO₂, sulfur and halides in a solid-phase calcium-containing product comprising CaCO₃, CaS and CaX₂; (iii) separating the solid-phase calcium-containing product from an enriched gaseous hydrogen product; and (iv) regenerating the CaO by calcining the solid-phase calcium-containing product at a condition selected from the group consisting of: in the presence of steam, in the presence of CO₂, in the presence of synthesis gas, in the presence of H₂and O₂, under partial vacuum, and combinations thereof.
FILED	Monday, May 13, 2013
APPL NO	13/892681
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Separation B01D 53/10 (20130101) B01D 53/62 (20130101) B01D 2253/112 (20130101) B01D 2256/16 (20130101) B01D 2257/204 (20130101) B01D 2257/304 (20130101) B01D 2257/504 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/48 (20130101) C01B 3/344 (20130101) C01B 3/583 (20130101) Original (OR) Class C01B 2203/043 (20130101) C01B 2203/047 (20130101) C01B 2203/062 (20130101) C01B 2203/82 (20130101) C01B 2203/84 (20130101) C01B 2203/86 (20130101) C01B 2203/148 (20130101) C01B 2203/0283 (20130101) C01B 2203/0465 (20130101) C01B 2203/0475 (20130101) C01B 2203/0485 (20130101) C01B 2203/0827 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2300/1022 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/54 (20130101) C10J 2300/1612 (20130101) C10J 2300/1646 (20130101) C10J 2300/1653 (20130101) C10J 2300/1659 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/003 (20130101) C10K 1/004 (20130101) C10K 3/04 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Y02C 10/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/16 (20130101) Y02E 20/18 (20130101) Y02E 20/185 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09174920 — Integrated process of distillation with side reactors for synthesis of organic acid esters

US 09174920	Panchal et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	E3TEC SERVICE, LLC (Clarksville, Maryland); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
ASSIGNEE(S)	E3TEC Service, LLC (Clarksville, Maryland); Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S)	Chandrakant B. Panchal (Clarksville, Maryland); John C. Prindle (Baton Rouge, Louisiana); Aspi Kolah (Mason, Michigan); Dennis J. Miller (Okemos, Michigan); Carl T. Lira (East Lansing, Michigan)
ABSTRACT	An integrated process and system for synthesis of organic-acid esters is provided. The method of synthesizing combines reaction and distillation where an organic acid and alcohol composition are passed through a distillation chamber having a plurality of zones. Side reactors are used for drawing off portions of the composition and then recycling them to the distillation column for further purification. Water is removed from a pre-reactor prior to insertion into the distillation column. An integrated heat integration system is contained within the distillation column for further purification and optimizing efficiency in the obtaining of the final product.
FILED	Friday, October 17, 2014
APPL NO	14/517325
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Separation B01D 3/009 (20130101) Acyclic or Carbocyclic Compounds C07C 67/08 (20130101) Original (OR) Class
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09175050 — Polypeptide having swollenin activity and uses thereof

US 09175050	Schoonneveld-Bergmans et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Margot Elisabeth Francoise Schoonneveld-Bergmans (Delft, Netherlands); Wilbert Herman Marie Heijne (Dordrecht, Netherlands); Monica D. Vlasie (The Hague, Netherlands); Robbertus Antonius Damveld (Berkel En Rodenrijs, Netherlands)
ASSIGNEE(S)	DSM IP ASSETS B.V. (Heerlen, Netherlands)
INVENTOR(S)	Margot Elisabeth Francoise Schoonneveld-Bergmans (Delft, Netherlands); Wilbert Herman Marie Heijne (Dordrecht, Netherlands); Monica D. Vlasie (The Hague, Netherlands); Robbertus Antonius Damveld (Berkel En Rodenrijs, Netherlands)
ABSTRACT	The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 73% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 73% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins.
FILED	Thursday, June 23, 2011
APPL NO	13/805163
ART UNIT	1662 — Plants
CURRENT CPC	Peptides C07K 14/37 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2434 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 5/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09175231 — Methods of refining natural oils and methods of producing fuel compositions

US 09175231	Firth et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Bruce E. Firth (Buffalo Grove, Illinois); Sharon E. Kirk (New Lenox, Illinois); Vasudeo S. Gavaskar (Woodridge, Illinois)
ASSIGNEE(S)	Elevance Renewable Sciences, Inc. (Woodridge, Illinois)
INVENTOR(S)	Bruce E. Firth (Buffalo Grove, Illinois); Sharon E. Kirk (New Lenox, Illinois); Vasudeo S. Gavaskar (Woodridge, Illinois)
ABSTRACT	A method of refining a natural oil includes: (a) providing a feedstock that includes a natural oil; (b) reacting the feedstock in the presence of a metathesis catalyst to form a metathesized product that includes olefins and esters; (c) passivating residual metathesis catalyst with an agent selected from the group consisting of phosphorous acid, phosphinic acid, and a combination thereof; (d) separating the olefins in the metathesized product from the esters in the metathesized product; and (e) transesterifying the esters in the presence of an alcohol to form a transesterified product and/or hydrogenating the olefins to form a fully or partially saturated hydrogenated product. Methods for suppressing isomerization of olefin metathesis products produced in a metathesis reaction, and methods of producing fuel compositions are described.
FILED	Thursday, December 22, 2011
APPL NO	13/335538
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 45/00 (20130101) Original (OR) Class C10G 45/58 (20130101) C10G 2300/304 (20130101) C10G 2300/308 (20130101) C10G 2300/1014 (20130101) C10G 2400/04 (20130101) C10G 2400/08 (20130101) C10G 2400/20 (20130101) C10G 2400/22 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/08 (20130101) C10L 1/026 (20130101) C10L 2200/0469 (20130101) C10L 2200/0476 (20130101) C10L 2270/04 (20130101) C10L 2270/026 (20130101)
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09175235 — Torrefaction reduction of coke formation on catalysts used in esterification and cracking of biofuels from pyrolysed lignocellulosic feedstocks

US 09175235	Kastner et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S)	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
INVENTOR(S)	James R. Kastner (Athens, Georgia); Sudhagar Mani (Watkinsville, Georgia); Roger Hilten (Winterville, Georgia); Keshav C. Das (Athens, Georgia)
ABSTRACT	A bio-oil production process involving torrefaction pretreatment, catalytic esterification, pyrolysis, and secondary catalytic processing significantly reduces yields of reactor char, catalyst coke, and catalyst tar relative to the best-case conditions using non-torrefied feedstock. The reduction in coke as a result of torrefaction was 28.5% relative to the respective control for slow pyrolysis bio-oil upgrading. In fast pyrolysis bio-oil processing, the greatest reduction in coke was 34.9%. Torrefaction at 275° C. reduced levels of acid products including acetic acid and formic acid in the bio-oil, which reduced catalyst coking and increased catalyst effectiveness and aromatic hydrocarbon yields in the upgraded oils. The process of bio-oil generation further comprises a catalytic esterification of acids and aldehydes to generate such as ethyl levulinate from lignified biomass feedstock.
FILED	Thursday, November 14, 2013
APPL NO	14/080153
ART UNIT	1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/002 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) Original (OR) Class
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09175275 — Celluloytic enzymes, nucleic acids encoding them and methods for making and using them

US 09175275	Gray et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	BP Corporation North America Inc. (Houston, Texas); Verenium Corporation (San Diego, California)
ASSIGNEE(S)	BP Corporation North America Inc. (Houston, Texas)
INVENTOR(S)	Kevin A. Gray (San Diego, California); Lishan Zhao (Emeryville, California); Michelle H. Cayouette (Potomac, Maryland)
ABSTRACT	The invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, β-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention.
FILED	Monday, January 28, 2013
APPL NO	13/751923
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/248 (20130101) C12N 9/2402 (20130101) C12N 9/2405 (20130101) C12N 9/2437 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101) C12Y 302/01006 (20130101) C12Y 302/01008 (20130101) C12Y 302/01021 (20130101) C12Y 302/01023 (20130101) C12Y 302/01039 (20130101) C12Y 302/01055 (20130101) C12Y 302/01091 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249921 (20150401)
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09175276 — Polypeptides having endoglucanase activity and polynucleotides encoding same

US 09175276	Spodsberg
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Novozymes A/S (Bagsvaerd, Denmark); Novozymes Inc. (Davis, California)
ASSIGNEE(S)	Novozymes, Inc. (Davis, California)
INVENTOR(S)	Nikolaj Spodsberg (Bagsvaerd, Denmark)
ABSTRACT	The present invention relates to isolated polypeptides having endoglucanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
FILED	Tuesday, February 12, 2013
APPL NO	13/764949
ART UNIT	1662 — Plants
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 21/02 (20130101) C12P 2203/00 (20130101)
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09175277 — Compositions for saccharification of cellulosic material

US 09175277	McBrayer et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Novozymes, Inc. (Davis, California)
ASSIGNEE(S)	NOVOZYMES, INC. (Davis, California)
INVENTOR(S)	Brett McBrayer (Sacramento, California); Tarana Shaghasi (Dixon, California); Elena Vlasenko (Davis, California)
ABSTRACT	The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof.
FILED	Friday, October 11, 2013
APPL NO	14/052360
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/22 (20130101) C12N 9/2437 (20130101) Original (OR) Class C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) Enzymes C12Y 302/01004 (20130101) C12Y 302/01021 (20130101) C12Y 302/01091 (20130101)
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09175323 — Process for treating biomass

US 09175323	Campbell et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	THE MICHIGAN BIOTECHNOLOGY INSTITUTE (Lansing, Michigan)
ASSIGNEE(S)	THE MICHIGAN BIOTECHNOLOGY INSTITUTE (Lansing, Michigan)
INVENTOR(S)	Timothy J. Campbell (East Lansing, Michigan); Farzaneh Teymouri (Okemos, Michigan)
ABSTRACT	This invention is directed to a process for treating biomass. The biomass is treated with a biomass swelling agent within the vessel to swell or rupture at least a portion of the biomass. A portion of the swelling agent is removed from a first end of the vessel following the treatment. Then steam is introduced into a second end of the vessel different from the first end to further remove swelling agent from the vessel in such a manner that the swelling agent exits the vessel at a relatively low water content.
FILED	Wednesday, April 24, 2013
APPL NO	14/391481
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 19/00 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2201/00 (20130101) Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 1/02 (20130101) D21C 1/06 (20130101) D21C 5/005 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/343 (20130101)
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09175397 — Multilayer heterostructures and their manufacture

US 09175397	Hammond et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) National Renewable Energy Laboratory (NREL) Federally Funded Research and Development Center (FFRDC) Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)	Scott R. Hammond (Golden, Colorado); Matthew Reese (Golden, Colorado); Benjamin Rupert (Berkeley, California); Alexander Miedaner (Boulder, Colorado); Calvin Curtis (Golden, Colorado); Dana Olson (Golden, Colorado); David S. Ginley (Evergreen, Colorado)
ASSIGNEE(S)	Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S)	Scott R. Hammond (Golden, Colorado); Matthew Reese (Golden, Colorado); Benjamin Rupert (Berkeley, California); Alexander Miedaner (Boulder, Colorado); Calvin Curtis (Golden, Colorado); Dana Olson (Golden, Colorado); David S. Ginley (Evergreen, Colorado)
ABSTRACT	A method of synthesizing multilayer heterostructures including an inorganic oxide layer residing on a solid substrate is described. Exemplary embodiments include producing an inorganic oxide layer on a solid substrate by a liquid coating process under relatively mild conditions. The relatively mild conditions include temperatures below 225° C. and pressures above 9.4 mb. In an exemplary embodiment, a solution of diethyl aluminum ethoxide in anhydrous diglyme is applied to a flexible solid substrate by slot-die coating at ambient atmospheric pressure, and the diglyme removed by evaporation. An AlO_xlayer is formed by subjecting material remaining on the solid substrate to a relatively mild oven temperature of approximately 150° C. The resulting AlO_xlayer exhibits relatively high light transmittance and relatively low vapor transmission rates for water. An exemplary embodiment of a flexible solid substrate is polyethylene napthalate (PEN). The PEN is not substantially adversely affected by exposure to 150° C.
FILED	Tuesday, March 15, 2011
APPL NO	13/048251
ART UNIT	1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/38 (20130101) B05D 3/0254 (20130101) B05D 7/02 (20130101) B05D 7/04 (20130101) B05D 7/22 (20130101) B05D 7/52 (20130101) B05D 2350/60 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/12 (20130101) C23C 18/1216 (20130101) Original (OR) Class C23C 18/1225 (20130101) C23C 18/1233 (20130101) C23C 18/1295 (20130101)
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09175402 — Turbine repair process, repaired coating, and repaired turbine component

US 09175402	Das et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Rupak Das (Greenville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina); Andres Jose Garcia-Crespo (Greenville, South Carolina)
ASSIGNEE(S)	General Electric Company (Schenectady, New York)
INVENTOR(S)	Rupak Das (Greenville, South Carolina); John McConnell Delvaux (Fountain Inn, South Carolina); Andres Jose Garcia-Crespo (Greenville, South Carolina)
ABSTRACT	A turbine repair process, a repaired coating, and a repaired turbine component are disclosed. The turbine repair process includes providing a turbine component having a higher-pressure region and a lower-pressure region, introducing particles into the higher-pressure region, and at least partially repairing an opening between the higher-pressure region and the lower-pressure region with at least one of the particles to form a repaired turbine component. The repaired coating includes a silicon material, a ceramic matrix composite material, and a repaired region having the silicon material deposited on and surrounded by the ceramic matrix composite material. The repaired turbine component a ceramic matrix composite layer and a repaired region having silicon material deposited on and surrounded by the ceramic matrix composite material.
FILED	Monday, July 30, 2012
APPL NO	13/561445
ART UNIT	3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/08 (20130101) Original (OR) Class C23C 30/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49238 (20150115) Y10T 428/20 (20150115)
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09175408 — Microbial production of multi-carbon chemicals and fuels from water and carbon dioxide using electric current

US 09175408	Lovley et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E) Office of Science (DOE-SC)
APPLICANT(S)	Derek R. Lovley (Leyden, Massachusetts); Kelly Nevin (Amherst, Massachusetts)
ASSIGNEE(S)	UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S)	Derek R. Lovley (Leyden, Massachusetts); Kelly Nevin (Amherst, Massachusetts)
ABSTRACT	The invention provides systems and methods for generating organic compounds using carbon dioxide as a source of carbon and electrical current as an energy source. In one embodiment, a reaction cell is provided having a cathode electrode and an anode electrode that are connected to a source of electrical power, and which are separated by a permeable membrane. A biological film is provided on the cathode. The biological film comprises a bacterium that can accept electrons and that can convert carbon dioxide to a carbon-bearing compound and water in a cathode half-reaction. At the anode, water is decomposed to free molecular oxygen and solvated protons in an anode half-reaction. The half-reactions are driven by the application of electrical current from an external source. Compounds that have been produced include acetate, butanol, 2-oxobutyrate, propanol, ethanol, and formate.
FILED	Wednesday, December 22, 2010
APPL NO	13/514378
ART UNIT	1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/16 (20130101) C12P 7/40 (20130101) C12P 7/54 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/00 (20130101) Original (OR) Class C25B 3/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101)
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09175604 — Gas turbine engine with high and intermediate temperature compressed air zones

US 09175604	Charron et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Richard C. Charron (West Palm Beach, Florida); David A. Little (Chuluota, Florida)
ASSIGNEE(S)	Siemens Energy, Inc. (Orlanda, Florida)
INVENTOR(S)	Richard C. Charron (West Palm Beach, Florida); David A. Little (Chuluota, Florida)
ABSTRACT	A gas turbine combustor (26) disposed in a combustion air plenum (65) and a transition piece (28) for the combustor disposed in a separate cooling air plenum (58, 67). The combustion air plenum may receive combustion air (50) from a high-pressure compressor stage (22A). The cooling air plenum may receive cooling air (52) from an intermediate-pressure compressor stage (22B) at lower temperature and pressure than the combustion air. This cools the transition piece using less air than prior systems, thus making the gas turbine engine (20) more efficient and less expensive, because less expensive materials are needed and/or higher combustion temperatures are allowed. The cooling air may exit the cooling air plenum through holes (62) in a downstream portion (61) of the transition piece. An outer wall (72) on the transition piece may provide forced convection along the transition piece.
FILED	Thursday, September 08, 2011
APPL NO	13/227769
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/14 (20130101) Original (OR) Class Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/04 (20130101) F23R 3/26 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 20/16 (20130101)
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09175608 — Split ring floating air riding seal for a turbine

US 09175608	Mills
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Jacob A Mills (Jupiter, Florida)
ASSIGNEE(S)	Florida Turbine Technologies, Inc. (Jupiter, Florida)
INVENTOR(S)	Jacob A Mills (Jupiter, Florida)
ABSTRACT	A floating air riding seal for a gas turbine engine with a rotor and a stator, an annular piston chamber with an axial moveable annular piston assembly within the annular piston chamber, an annular cavity formed on the annular piston assembly that faces a seal surface on the rotor, and a central passage connecting the annular cavity to the annular piston chamber to supply compressed air to the seal face, where the annular piston assembly is a split piston assembly to maintain a tight seal as coning of the rotor disk occurs.
FILED	Monday, March 11, 2013
APPL NO	13/793853
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Original (OR) Class
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09175644 — Engine with exhaust gas recirculation system and variable geometry turbocharger

US 09175644	Keating
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) Office of Fossil Energy and Carbon Management (FECM) National Energy Technology Laboratory (NETL)
APPLICANT(S)	GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
ASSIGNEE(S)	GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S)	Edward J. Keating (Ortonville, Michigan)
ABSTRACT	An engine assembly includes an intake assembly, an internal combustion engine defining a plurality of cylinders and configured to combust a fuel and produce exhaust gas, and an exhaust assembly in fluid communication with a first subset of the plurality of cylinders. Each of the plurality of cylinders are provided in fluid communication with the intake assembly. The exhaust assembly is provided in fluid communication with a first subset of the plurality of cylinders, and a dedicated exhaust gas recirculation system in fluid communication with both a second subset of the plurality of cylinders and with the intake assembly. The dedicated exhaust gas recirculation system is configured to route all of the exhaust gas from the second subset of the plurality of cylinders to the intake assembly. Finally, the engine assembly includes a turbocharger having a variable geometry turbine in fluid communication with the exhaust assembly.
FILED	Wednesday, April 24, 2013
APPL NO	13/869323
ART UNIT	3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 25/0722 (20130101) Original (OR) Class F02M 25/0749 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/121 (20130101)
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09175882 — Solar energy system with wind vane

US 09175882	Grip
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Robert E. Grip (Rancho Palos Verdes, California)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	Robert E. Grip (Rancho Palos Verdes, California)
ABSTRACT	A solar energy system including a pedestal defining a longitudinal axis, a frame that is supported by the pedestal and that is rotateable relative to the pedestal about the longitudinal axis, the frame including at least one solar device, and a wind vane operatively connected to the frame to urge the frame relative to the pedestal about the longitudinal axis in response to wind acting on the wind vane.
FILED	Thursday, March 18, 2010
APPL NO	12/726593
ART UNIT	3749 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Producing or Use of Heat Not Otherwise Provided For F24J 2/542 (20130101) Original (OR) Class F24J 2/4638 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/47 (20130101)
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09176028 — Ball assisted device for analytical surface sampling

US 09176028	ElNaggar et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee); DH Technologies Development Pte. Ltd. (, None)
ASSIGNEE(S)	UT-BATTELLE, LLC (Oak Ridge, Tennessee); DH TECHNOLOGIES DEVELOPMENT PTE. LTD (Singapore, Singapore)
INVENTOR(S)	Mariam S. ElNaggar (Indianapolis, Indiana); Gary J. Van Berkel (Oak Ridge, Tennessee); Thomas R. Covey (Richmond Hill, California)
ABSTRACT	A system for sampling a surface includes a sampling probe having a housing and a socket, and a rolling sampling sphere within the socket. The housing has a sampling fluid supply conduit and a sampling fluid exhaust conduit. The sampling fluid supply conduit supplies sampling fluid to the sampling sphere. The sampling fluid exhaust conduit has an inlet opening for receiving sampling fluid carried from the surface by the sampling sphere. A surface sampling probe and a method for sampling a surface are also disclosed.
FILED	Thursday, October 04, 2012
APPL NO	13/644941
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) Original (OR) Class G01N 2001/028 (20130101)
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09176065 — Nanoscale array structures suitable for surface enhanced raman scattering and methods related thereto

US 09176065	Bond et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California); The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Tiziana C. Bond (Livermore, California); Robin Miles (Danville, California); James C. Davidson (Livermore, California); Gang Logan Liu (Champaign, Illinois)
ABSTRACT	Methods for fabricating nanoscale array structures suitable for surface enhanced Raman scattering, structures thus obtained, and methods to characterize the nanoscale array structures suitable for surface enhanced Raman scattering. Nanoscale array structures may comprise nanotrees, nanorecesses and tapered nanopillars.
FILED	Thursday, June 26, 2014
APPL NO	14/316024
ART UNIT	2886 — Optics
CURRENT CPC	Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00373 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/658 (20130101) Original (OR) Class
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09177249 — Scientometric methods for identifying emerging technologies

US 09177249	Abercrombie et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Robert K. Abercrombie (Knoxville, Tennessee); Bob G. Schlicher (Knoxville, Tennessee); Frederick T. Sheldon (Knoxville, Tennessee)
ABSTRACT	Provided is a method of generating a scientometric model that tracks the emergence of an identified technology from initial discovery (via original scientific and conference literature), through critical discoveries (via original scientific, conference literature and patents), transitioning through Technology Readiness Levels (TRLs) and ultimately on to commercial application. During the period of innovation and technology transfer, the impact of scholarly works, patents and on-line web news sources are identified. As trends develop, currency of citations, collaboration indicators, and on-line news patterns are identified. The combinations of four distinct and separate searchable on-line networked sources (i.e., scholarly publications and citation, worldwide patents, news archives, and on-line mapping networks) are assembled to become one collective network (a dataset for analysis of relations). This established network becomes the basis from which to quickly analyze the temporal flow of activity (searchable events) for the example subject domain.
FILED	Wednesday, June 26, 2013
APPL NO	13/927141
ART UNIT	2129 — AI & Simulation/Modeling
CURRENT CPC	Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0637 (20130101) G06Q 30/0201 (20130101) G06Q 30/0202 (20130101)
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09177679 — Accelerator-based method of producing isotopes

US 09177679	Nolen, Jr. et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Jerry A. Nolen, Jr. (Chicago, Illinois); Itacil C. Gomes (Naperville, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Jerry A. Nolen, Jr. (Chicago, Illinois); Itacil C. Gomes (Naperville, Illinois)
ABSTRACT	The invention provides a method using accelerators to produce radio-isotopes in high quantities. The method comprises: supplying a “core” of low-enrichment fissile material arranged in a spherical array of LEU combined with water moderator. The array is surrounded by substrates which serve as multipliers and moderators as well as neutron shielding substrates. A flux of neutrons enters the low-enrichment fissile material and causes fissions therein for a time sufficient to generate desired quantities of isotopes from the fissile material. The radio-isotopes are extracted from said fissile material by chemical processing or other means.
FILED	Friday, February 11, 2011
APPL NO	13/026102
ART UNIT	3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Conversion of Chemical Elements; Radioactive Sources G21G 1/00 (20130101) G21G 1/08 (20130101) Original (OR) Class G21G 1/10 (20130101) G21G 2001/0036 (20130101)
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09177748 — Pulsed depressed collector

US 09177748	Kemp
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) SLAC National Accelerator Laboratory (SLAC) Federally Funded Research and Development Center (FFRDC) Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Mark A. Kemp (Belmont, California)
ABSTRACT	A high power RF device has an electron beam cavity, a modulator, and a circuit for feed-forward energy recovery from a multi-stage depressed collector to the modulator. The electron beam cavity include a cathode, an anode, and the multi-stage depressed collector, and the modulator is configured to provide pulses to the cathode. Voltages of the electrode stages of the multi-stage depressed collector are allowed to float as determined by fixed impedances seen by the electrode stages. The energy recovery circuit includes a storage capacitor that dynamically biases potentials of the electrode stages of the multi-stage depressed collector and provides recovered energy from the electrode stages of the multi-stage depressed collector to the modulator. The circuit may also include a step-down transformer, where the electrode stages of the multi-stage depressed collector are electrically connected to separate taps on the step-down transformer.
FILED	Thursday, February 06, 2014
APPL NO	14/174637
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Electric Discharge Tubes or Discharge Lamps H01J 23/34 (20130101) H01J 23/0275 (20130101) Original (OR) Class
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09178160 — Fused thiophene-based conjugated polymers and their use in optoelectronic devices

US 09178160	Facchetti et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	Northwestern University (Evanston, Illinois); Polyera Corporation (Skokie, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois); Polyera Corporation (Skokie, Illinois)
INVENTOR(S)	Antonio Facchetti (Chicago, Illinois); Tobin J. Marks (Evanston, Illinois); Atsuro Takai (Evanston, Illinois); Mark Seger (Chicago, Illinois); Zhihua Chen (Skokie, Illinois)
ABSTRACT	The present teachings relate to certain polymeric compounds and their use as organic semiconductors in organic and hybrid optical, optoelectronic, and/or electronic devices such as photovoltaic cells, light emitting diodes, light emitting transistors, and field effect transistors. The disclosed compounds can provide improved device performance, for example, as measured by power conversion efficiency, fill factor, open circuit voltage, field-effect mobility, on/off current ratios, and/or air stability when used in photovoltaic cells or transistors. The disclosed compounds can have good solubility in common solvents enabling device fabrication via solution processes.
FILED	Tuesday, October 21, 2014
APPL NO	14/520304
ART UNIT	1622 — Organic Chemistry
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0035 (20130101) H01L 51/0036 (20130101) H01L 51/42 (20130101) H01L 51/0043 (20130101) Original (OR) Class
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09178200 — Electrochemical cells and methods of manufacturing the same

US 09178200	Bazzarella et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	24M Technologies, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	24M Technologies, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Ricardo Bazzarella (Woburn, Massachusetts); Alexander H. Slocum (Bow, New Hampshire); Tristan Doherty (Somerville, Massachusetts); James C. Cross, III (Carlisle, Massachusetts)
ABSTRACT	Electrochemical cells and methods of making electrochemical cells are described herein. In some embodiments, an apparatus includes a multi-layer sheet for encasing an electrode material for an electrochemical cell. The multi-layer sheet including an outer layer, an intermediate layer that includes a conductive substrate, and an inner layer disposed on a portion of the conductive substrate. The intermediate layer is disposed between the outer layer and the inner layer. The inner layer defines an opening through which a conductive region of the intermediate layer is exposed such that the electrode material can be electrically connected to the conductive region. Thus, the intermediate layer can serve as a current collector for the electrochemical cell.
FILED	Friday, March 15, 2013
APPL NO	13/832836
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/027 (20130101) H01M 2/0207 (20130101) H01M 2/0287 (20130101) H01M 2/1653 (20130101) Original (OR) Class H01M 6/46 (20130101) H01M 10/0404 (20130101) H01M 10/0413 (20130101) H01M 10/0436 (20130101) H01M 10/0585 (20130101)
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09178235 — Reducing gas generators and methods for generating a reducing gas

US 09178235	Scotto et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Mark Vincent Scotto (Uniontown, Ohio); Mark Anthony Perna (Alliance, Ohio)
ASSIGNEE(S)	LG Fuel Cell Systems, Inc. (North Canton, Ohio)
INVENTOR(S)	Mark Vincent Scotto (Uniontown, Ohio); Mark Anthony Perna (Alliance, Ohio)
ABSTRACT	One embodiment of the present invention is a unique reducing gas generator. Another embodiment is a unique method for generating a reducing gas. Other embodiments include apparatuses, systems, devices, hardware, methods, and combinations for generating reducing gas. Further embodiments, forms, features, aspects, benefits, and advantages of the present application will become apparent from the description and figures provided herewith.
FILED	Thursday, June 30, 2011
APPL NO	13/174044
ART UNIT	1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Non-metallic Elements; Compounds Thereof; C01B 3/38 (20130101) C01B 3/382 (20130101) C01B 3/386 (20130101) C01B 2203/066 (20130101) C01B 2203/142 (20130101) C01B 2203/0261 (20130101) C01B 2203/1604 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0618 (20130101) Original (OR) Class H01M 8/04268 (20130101) H01M 8/04328 (20130101) H01M 8/04425 (20130101) H01M 8/04731 (20130101) H01M 8/04776 (20130101) H01M 8/04798 (20130101) H01M 2008/1293 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Y02E 60/525 (20130101)
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09178240 — System and process for aluminization of metal-containing substrates

US 09178240	Chou et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Yeong-Shyung Chou (Richland, Washington); Jeffry W. Stevenson (Richland, Washington)
ASSIGNEE(S)	BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S)	Yeong-Shyung Chou (Richland, Washington); Jeffry W. Stevenson (Richland, Washington)
ABSTRACT	A system and method are detailed for aluminizing surfaces of metallic substrates, parts, and components with a protective alumina layer in-situ. Aluminum (Al) foil sandwiched between the metallic components and a refractory material when heated in an oxidizing gas under a compression load at a selected temperature forms the protective alumina coating on the surface of the metallic components. The alumina coating minimizes evaporation of volatile metals from the metallic substrates, parts, and components in assembled devices during operation at high temperature that can degrade performance.
FILED	Tuesday, August 13, 2013
APPL NO	13/966073
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/10 (20130101) C23C 8/12 (20130101) C23C 26/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0208 (20130101) H01M 8/0228 (20130101) H01M 8/0273 (20130101) H01M 8/1246 (20130101) Original (OR) Class H01M 2008/1293 (20130101)
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09178249 — Electrode stabilizing materials

US 09178249	Amine et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	Khalil Amine (Oakbrook, Illinois); Ali Abouimrane (Woodridge, Illinois); Jeffrey S. Moore (Savoy, Illinois); Susan A. Odom (Champaign, Illinois)
ASSIGNEE(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S)	Khalil Amine (Oakbrook, Illinois); Ali Abouimrane (Woodridge, Illinois); Jeffrey S. Moore (Savoy, Illinois); Susan A. Odom (Champaign, Illinois)
ABSTRACT	An electrolyte includes a polar aprotic solvent; an alkali metal salt; and an electrode stabilizing compound that is a monomer, which when polymerized forms an electrically conductive polymer. The electrode stabilizing compound is a thiophene, a imidazole, a anilines, a benzene, a azulene, a carbazole, or a thiol. Electrochemical devices may incorporate such electrolytes.
FILED	Thursday, May 26, 2011
APPL NO	13/116863
ART UNIT	1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 10/052 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 2300/0025 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101)
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09178334 — Arbitrary waveform generator to improve laser diode driver performance

US 09178334	Fulkerson, Jr.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Edward Steven Fulkerson, Jr. (Livermore, California)
ABSTRACT	An arbitrary waveform generator modifies the input signal to a laser diode driver circuit in order to reduce the overshoot/undershoot and provide a “flat-top” signal to the laser diode driver circuit. The input signal is modified based on the original received signal and the feedback from the laser diode by measuring the actual current flowing in the laser diode after the original signal is applied to the laser diode.
FILED	Thursday, February 21, 2013
APPL NO	14/378622
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0941 (20130101) H01S 5/0428 (20130101) H01S 5/4025 (20130101) H01S 5/06223 (20130101) Original (OR) Class H01S 5/06808 (20130101) H01S 5/06835 (20130101)
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09178349 — Method and system for architecture, control, and protection systems of modular stacked direct current subsea power system

US 09178349	Dong et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	General Electric Company (Niskayuna, New York)
INVENTOR(S)	Dong Dong (Schenectady, New York); Rixin Lai (Clifton Park, New York); Song Chi (Clifton Park, New York); Ranjan Kumar Gupta (Schenectady, New York); Di Zhang (Niskayuna, New York)
ABSTRACT	A high-voltage DC (HVDC) power system and a method of controlling and protecting the HVDC power system includes a plurality of sending-end (SE) modules coupled in electrical series and a plurality of receiving-end (RE) power converter modules electrically coupled to said plurality of SE modules, the RE modules coupled in a switchyard configuration, the switchyard configuration including a plurality of load branches coupled together in electrical series, each load branch including a branch bypass switch configured to bypass load current around an associated load branch, and a branch protection system.
FILED	Wednesday, September 11, 2013
APPL NO	14/024315
ART UNIT	2836 — Electrical Circuits and Systems
CURRENT CPC	Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 41/00 (20130101) Emergency Protective Circuit Arrangements H02H 3/16 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/36 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/00 (20130101) H02M 11/00 (20130101)
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09178446 — Triboelectric generator

US 09178446	Wang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Basic Energy Sciences (BES)
APPLICANT(S)	Zhong L. Wang (Marietta, Georgia); Fengru Fan (Atlanta, Georgia); Long Lin (Atlanta, Georgia); Guang Zhu (Atlanta, Georgia); Caofeng Pan (Atlanta, Georgia); Yusheng Zhou (Atlanta, Georgia)
ASSIGNEE(S)	Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S)	Zhong L. Wang (Marietta, Georgia); Fengru Fan (Atlanta, Georgia); Long Lin (Atlanta, Georgia); Guang Zhu (Atlanta, Georgia); Caofeng Pan (Atlanta, Georgia); Yusheng Zhou (Atlanta, Georgia)
ABSTRACT	A generator includes a thin first contact charging layer and a thin second contact charging layer. The thin first contact charging layer includes a first material that has a first rating on a triboelectric series. The thin first contact charging layer has a first side with a first conductive electrode applied thereto and an opposite second side. The thin second contact charging layer includes a second material that has a second rating on a triboelectric series that is more negative than the first rating. The thin first contact charging layer has a first side with a first conductive electrode applied thereto and an opposite second side. The thin second contact charging layer is disposed adjacent to the first contact charging layer so that the second side of the second contact charging layer is in contact with the second side of the first contact charging layer.
FILED	Wednesday, August 29, 2012
APPL NO	13/598132
ART UNIT	2834 — Electrical Circuits and Systems
CURRENT CPC	Electric Machines Not Otherwise Provided for H02N 1/04 (20130101) Original (OR) Class
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09179047 — Systems and methods for estimating the structure and motion of an object

US 09179047	Dani et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF)
APPLICANT(S)	Ashwin P. Dani (Urbana, Illinois); Warren Dixon (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Ashwin P. Dani (Urbana, Illinois); Warren Dixon (Gainesville, Florida)
ABSTRACT	In one embodiment, the structure and motion of a stationary object are determined using two images and a linear velocity and linear acceleration of a camera. In another embodiment, the structure and motion of a stationary or moving object are determined using an image and linear and angular velocities of a camera.
FILED	Wednesday, June 13, 2012
APPL NO	14/126148
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/24 (20130101) Image Data Processing or Generation, in General G06T 7/0065 (20130101) G06T 7/2033 (20130101) G06T 2207/10032 (20130101) G06T 2207/30244 (20130101) Pictorial Communication, e.g Television H04N 5/225 (20130101) Original (OR) Class
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National Science Foundation (NSF)

09173384 — Surgically implanted micro-platforms and microsystems in arthropods and methods based thereon

US 09173384	Lal et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) National Science Foundation (NSF)
APPLICANT(S)	Amit Lal (Ithaca, New York); John Ewer (Valparaiso, Chile); Ayesa Kaur (Ithaca, New York); Alper Bozkurt (Ithaca, New York)
ASSIGNEE(S)	Cornell University (Ithaca, New York)
INVENTOR(S)	Amit Lal (Ithaca, New York); John Ewer (Valparaiso, Chile); Ayesa Kaur (Ithaca, New York); Alper Bozkurt (Ithaca, New York)
ABSTRACT	A method is provided for producing an arthropod comprising introducing a microsystem such as a MEMS device into an immature arthropod under conditions that result in producing an adult arthropod with a functional microsystem permanently attached to its body. A method is also provided for producing a robotic apparatus. The method can comprise introducing a microsystem such as a MEMS device into an immature arthropod under conditions that result in producing a robotic apparatus with the microsystem permanently attached to the body of the adult arthropod.
FILED	Tuesday, December 11, 2007
APPL NO	12/518847
ART UNIT	3766 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/033 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/372 (20130101) A61N 1/3605 (20130101)
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09173562 — Method and apparatus for diagnosing neovascularized tissues

US 09173562	Sardar et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF)
APPLICANT(S)	Dhiraj Sardar (San Antonio, Texas); Andrew T. C. Tsin (Fair Oaks Ranch, Texas)
ASSIGNEE(S)	The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S)	Dhiraj Sardar (San Antonio, Texas); Andrew T. C. Tsin (Fair Oaks Ranch, Texas)
ABSTRACT	Disclosed is a method for detecting neovascularized tissue that includes placing a tissue in the path of a light beam, measuring a polarization shift of the light beam, and detecting neovascularized tissue if the measured polarization shift corresponds to a polarization shift of a neovascularized tissue. Also disclosed is an apparatus for detecting neovascularized tissue that includes a laser, a polarizer coupled to the laser, a tissue sample holder coupled to the polarizer, an analyzer coupled to the tissue sample holder, a detector coupled to the analyzer, and a data acquisition system coupled to the detector, wherein the data acquisition system is configured to measure a polarization shift of a light beam emitted by the laser and diagnose an ocular disease if the measured polarization shift corresponds to a polarization shift of a neovascularized tissue.
FILED	Friday, January 23, 2004
APPL NO	10/543001
ART UNIT	3777 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Diagnosis; Surgery; Identification A61B 3/1225 (20130101) Original (OR) Class A61B 5/0059 (20130101)
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09173574 — Mechanical health monitor apparatus and method of operation therefor

US 09173574	Teixeira et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Rodrigo E. Teixeira (Madison, Alabama); Alton Reich (Huntsville, Alabama)
ASSIGNEE(S)
INVENTOR(S)	Rodrigo E. Teixeira (Madison, Alabama); Alton Reich (Huntsville, Alabama)
ABSTRACT	A probabilistic data signal processor used to determine health of a system is described. Initial probability distribution functions are input to a dynamic state-space model, which iteratively operates on probability distribution functions, such as state and model probability distribution functions, to generate a prior probability distribution function, which is input to a probabilistic updater. The probabilistic updater integrates sensor data with the prior to generate a posterior probability distribution function passed to a probabilistic sampler, which estimates one or more parameters using the posterior, which is output or re-sampled and used as an input to the dynamic state-space model in the iterative algorithm. In various embodiments, the probabilistic data signal processor is used to filter output from any mechanical device using appropriate physical models, which optionally include chemical, electrical, optical, mechanical, or fluid based models. Examples to valve bearings and pipe systems are provided.
FILED	Thursday, April 28, 2011
APPL NO	13/096845
ART UNIT	2863 — Printing/Measuring and Testing
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0205 (20130101) Original (OR) Class A61B 5/0402 (20130101) A61B 5/7203 (20130101) A61B 5/7214 (20130101) A61B 5/7278 (20130101) A61B 5/14551 (20130101)
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09173950 — Vitamin D-ghrelin conjugates

US 09173950	Soliman et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Extend Biosciences, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	Extend Biosciences, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Howard P. Sard (Arlington, Massachusetts); Mukkanti Amere (Woburn, Massachusetts)
ABSTRACT	The invention provides carriers that enhance the absorption, half-life or bioavailability of Ghrelin peptides. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties.
FILED	Saturday, November 15, 2014
APPL NO	14/542581
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) A61K 47/4813 (20130101) A61K 47/48107 (20130101) A61K 47/48215 (20130101) Original (OR) Class
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09174173 — Chemical processing cell with nanostructured membranes

US 09174173	Bhattacharyya et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Dibakar Bhattacharyya (Lexington, Kentucky); Scott R. Lewis (Wilmington, Delaware); Saurav Datta (Darien, Illinois)
ASSIGNEE(S)	UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S)	Dibakar Bhattacharyya (Lexington, Kentucky); Scott R. Lewis (Wilmington, Delaware); Saurav Datta (Darien, Illinois)
ABSTRACT	A chemical processing cell includes an upstream membrane and a downstream membrane. The upstream membrane generates a first reaction product. The downstream membrane converts the first reaction product to a second reaction product.
FILED	Monday, April 30, 2012
APPL NO	13/459323
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Separation B01D 67/0079 (20130101) B01D 67/0088 (20130101) B01D 67/0093 (20130101) B01D 69/10 (20130101) Original (OR) Class B01D 71/022 (20130101) B01D 71/34 (20130101) B01D 71/40 (20130101) B01D 71/44 (20130101) B01D 2323/30 (20130101) B01D 2323/40 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 1/70 (20130101)
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09174186 — Supercrystalline colloidal particles and method of production

US 09174186	Cao et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Y. Charles Cao (Gainesville, Florida); Jiaqi Zhuang (Gainesville, Florida); Huimeng Wu (Gainesville, Florida); Yongan Yang (Golden, Colorado)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	Y. Charles Cao (Gainesville, Florida); Jiaqi Zhuang (Gainesville, Florida); Huimeng Wu (Gainesville, Florida); Yongan Yang (Golden, Colorado)
ABSTRACT	The present invention concerns size- and shape-controlled, colloidal superparticles (SPs) and methods for synthesizing the same. Ligand-functionalized nanoparticles such as nonpolar-solvent-dispersible nanoparticles, are used, and the solvophobic interactions can be controlled. Advantageously, supercrystalline SPs having a superlattice structure, such as a face-centered cubic structure, can be produced. Further, the methods of the invention can provide SPs that self-assemble and are monodisperse. The SPs can be doped with organic dyes and further assembled into more complex structures.
FILED	Friday, August 15, 2008
APPL NO	12/672447
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0026 (20130101) Original (OR) Class B01J 13/0043 (20130101)
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09174203 — Selective and efficient bifunctional and trifunctional nanoporous catalysts and methods of synthesis thereof

US 09174203	Asefa et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Tewodros Asefa (Somerset, New Jersey); Krishna K. Sharma (Cambridge, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Tewodros Asefa (Somerset, New Jersey); Krishna K. Sharma (Cambridge, Massachusetts)
ABSTRACT	Selective and efficient multifunctional nanoporous catalysts containing spatially distributed organoamine and silanol groups, and methods of preparation thereof. The catalysts have been observed to be very highly efficient in catalysis of the Henry reaction.
FILED	Monday, August 16, 2010
APPL NO	12/857400
ART UNIT	1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/0308 (20130101) Original (OR) Class B01J 31/0254 (20130101) Acyclic or Carbocyclic Compounds C07C 205/14 (20130101)
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09174893 — Synthesis of para-xylene and toluene

US 09174893	Brookhart et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Maurice Brookhart (Carrboro, North Carolina); Michael Findlater (Chapel Hill, North Carolina); Damien Guironnet (Charlotte, North Carolina); Thomas Warren Lyons (Carrboro, North Carolina)
ABSTRACT	A method of making para-xylene or toluene is carried out by: (a) reacting a C5 or C6 linear monoene (itself, or formed from a C5 or C6 linear alkane) with a hydrogen acceptor in the presence of a hydrogen transfer catalyst to produce a C5 or C6 diene; (b) reacting the C5-C6 diene with ethylene to produce a cyclohexene having 1 or 2 methyl groups substituted thereon; and then (c) either (i) dehydrogenating the cyclohexene in the presence of a hydrogen acceptor with a hydrogen transfer catalyst to produce a compound selected from the group consisting of para-xylene and toluene, or (ii) dehydrogenating the cyclohexene in the absence of a hydrogen acceptor with a dehydrogenation catalyst, to produce para-xylene or toluene.
FILED	Thursday, May 02, 2013
APPL NO	13/875610
ART UNIT	1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 2/52 (20130101) C07C 2/52 (20130101) C07C 2/72 (20130101) Original (OR) Class C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 5/42 (20130101) C07C 5/52 (20130101) C07C 5/52 (20130101) C07C 5/321 (20130101) C07C 5/321 (20130101) C07C 5/321 (20130101) C07C 11/12 (20130101) C07C 13/20 (20130101) C07C 15/06 (20130101) C07C 15/06 (20130101) C07C 15/08 (20130101) C07C 15/08 (20130101) C07C 2101/16 (20130101) C07C 2531/22 (20130101)
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09174934 — Aryl tetrafluorosulfanyl compounds

US 09174934	Welch et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
ASSIGNEE(S)	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S)	John Welch (Albany, New York); Linbin Zhong (Albany, New York)
ABSTRACT	The invention provides compounds of the Formula (I), methods of making the compounds, and devices comprising the compounds.
FILED	Tuesday, March 12, 2013
APPL NO	14/436474
ART UNIT	1672 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 319/14 (20130101) C07C 323/07 (20130101) Original (OR) Class C07C 323/09 (20130101) C07C 323/63 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/04 (20130101)
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09175026 — Synthesis of thioether containing trialkoxysilanes

US 09175026	Garrell et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Robin L. Garrell (Los Angeles, California); Alexander K. Tucker-Schwartz (Los Angeles, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Robin L. Garrell (Los Angeles, California); Alexander K. Tucker-Schwartz (Los Angeles, California)
ABSTRACT	The invention relates to a radical-initiated thiol-ene or thiol-yne “click” reaction that provides a simple and efficient route to diverse trialkoxysilanes. Trialkoxysilanes made in this way are obtained in quantitative to near-quantitative yields with high purity without any or minimal purification. A wide range of functional groups is tolerated in this approach, and even complex alkenes click with the silane precursors. The modular nature of these radical-based thiol-ene or thiol-yne “click” reactions allows a wide variety of pendant groups to be coupled to silane compounds that can then be coupled to a wide variety surfaces in order to modify their material properties. Consequently, such radical initiated thiol-ene and thiol-yne reactions provide facile and efficient methods for preparing an enormous number of surface-active functional trialkoxysilanes.
FILED	Thursday, March 22, 2012
APPL NO	14/001096
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Processes for Applying Fluent Materials to Surfaces, in General B05D 1/36 (20130101) B05D 1/185 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/08 (20130101) C07F 7/1876 (20130101) C07F 7/1892 (20130101) C07F 19/00 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/00 (20130101)
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09175103 — Living coordinative chain transfer polymerization with dynamic counterion exchange

US 09175103	Sita et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Lawrence R. Sita (Silver Spring, Maryland); Jia Wei (Beltsville, Maryland); Wei Zhang (Gaithersburg, Maryland)
ASSIGNEE(S)	University of Maryland, College Park (College Park, Maryland)
INVENTOR(S)	Lawrence R. Sita (Silver Spring, Maryland); Jia Wei (Beltsville, Maryland); Wei Zhang (Gaithersburg, Maryland)
ABSTRACT	Disclosed is a method of producing a polyolefin composition comprising contacting a metal alkyl and a first olefin monomer, then adding a first co-catalyst, a second co-catalyst, a pre-catalyst, and a second olefin monomer. The method allows for the production of a series of copolymers with tunable incorporation ratios of the first olefin monomer. The method also allows for the production of polyolefins of low molecular weights and narrow molecular weight distributions.
FILED	Friday, June 10, 2011
APPL NO	13/703212
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/38 (20130101) C08F 4/643 (20130101) Original (OR) Class C08F 4/6592 (20130101) C08F 4/6592 (20130101) C08F 4/65908 (20130101) C08F 210/14 (20130101) C08F 210/16 (20130101) C08F 210/16 (20130101) C08F 210/16 (20130101) C08F 210/16 (20130101) C08F 2410/01 (20130101) C08F 2420/01 (20130101) C08F 2420/02 (20130101) C08F 2500/03 (20130101)
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09176143 — Transmembrane protein as biosensors

US 09176143	Frommer et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Carnegie Institution of Washington (Washington, District of Columbia)
ASSIGNEE(S)	Carnegie Institution of Washington (Washington, District of Columbia)
INVENTOR(S)	Wolf B. Frommer (Washington, District of Columbia); Roberto De Michele (Washington, District of Columbia); Cindy Ast (Washington, District of Columbia)
ABSTRACT	The disclosure relates to engineered transport proteins comprising at last one fluorescent reporter covalently bound to the transporter protein, wherein the transporter proteins comprise a structural inverted repeat motif, with the motif comprising a first and second subunit that are structural inverted repeats of one another and that are joined to one another by a polypeptide loop.
FILED	Tuesday, September 18, 2012
APPL NO	14/345529
ART UNIT	1676 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Peptides C07K 14/415 (20130101) C07K 14/705 (20130101) C07K 2319/21 (20130101) C07K 2319/23 (20130101) C07K 2319/43 (20130101) C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) Original (OR) Class
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09176377 — Patterned inorganic layers, radiation based patterning compositions and corresponding methods

US 09176377	Stowers et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S)	Jason K. Stowers (Corvallis, Oregon); Alan J. Telecky (Corvallis, Oregon); Douglas A. Keszler (Corvallis, Oregon); Andrew Grenville (Eugene, Oregon)
ASSIGNEE(S)	Inpria Corporation (Corvallis, Oregon)
INVENTOR(S)	Jason K. Stowers (Corvallis, Oregon); Alan J. Telecky (Corvallis, Oregon); Douglas A. Keszler (Corvallis, Oregon); Andrew Grenville (Eugene, Oregon)
ABSTRACT	Stabilized precursor solutions can be used to form radiation inorganic coating materials. The precursor solutions generally comprise metal suboxide cations, peroxide-based ligands and polyatomic anions. Design of the precursor solutions can be performed to achieve a high level of stability of the precursor solutions. The resulting coating materials can be designed for patterning with a selected radiation, such as ultraviolet light, x-ray radiation or electron beam radiation. The radiation patterned coating material can have a high contrast with respect to material properties, such that development of a latent image can be successful to form lines with very low line-width roughness and adjacent structures with a very small pitch.
FILED	Thursday, August 05, 2010
APPL NO	12/850867
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0042 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/24355 (20150115)
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09176380 — Photoinduced alkyne-azide click reactions

US 09176380	Bowman et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Christopher Bowman (Boulder, Colorado); Brian A. Adzima (Boulder, Colorado); Christopher J. Kloxin (Boulder, Colorado)
ASSIGNEE(S)	The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S)	Christopher Bowman (Boulder, Colorado); Brian A. Adzima (Boulder, Colorado); Christopher J. Kloxin (Boulder, Colorado)
ABSTRACT	The present invention includes a composition comprising an alkyne-based substrate, an azide-based substrate, a Cu(II) salt and a photoinducible reducing agent. The present invention further includes a method of immobilizing a chemical structure in a given pattern onto a section of the surface of a solid substrate, using the photoinducible Cu(I)-catalyzed azide-alkyne cycloaddition Click reaction.
FILED	Monday, November 28, 2011
APPL NO	13/990218
ART UNIT	1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Heterocyclic Compounds C07D 249/04 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101) G03F 7/0085 (20130101) Original (OR) Class
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09176504 — High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation

US 09176504	Chiou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Aeronautics and Space Administration (NASA) National Science Foundation (NSF)
APPLICANT(S)	Pei-Yu Chiou (Los Angeles, California); Ting-Hsiang S. Wu (Los Angeles, California); Sung-Yong Park (Thousand Oaks, California); Michael A. Teitell (Tarzana, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Pei-Yu Chiou (Los Angeles, California); Ting-Hsiang S. Wu (Los Angeles, California); Sung-Yong Park (Thousand Oaks, California); Michael A. Teitell (Tarzana, California)
ABSTRACT	Methods and devices for the formation of droplets of a first fluid in a second fluid and the encapsulation of particles or cells within such droplets are disclosed. Impetus for droplet formation is provided by the creation of a transient bubble, which may be induced using a pulsed laser. Droplet volume and the frequency at which droplets are formed can be controlled by modulation of the pulsed laser. The disclosed methods and devices are particularly suitable for use in microfluidic devices.
FILED	Thursday, February 09, 2012
APPL NO	13/370196
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 21/64 (20130101) G01N 29/2418 (20130101) G01N 2015/1481 (20130101) G01N 2291/02433 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 11/13 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/2496 (20150401)
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09176883 — Storage of data reference blocks and deltas in different storage devices

US 09176883	Yang
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computing and Communication Foundations (CCF)
APPLICANT(S)	Qing Yang (Saunderstown, Rhode Island)
ASSIGNEE(S)	HGST NETHERLANDS B.V. (Amsterdam, Netherlands)
INVENTOR(S)	Qing Yang (Saunderstown, Rhode Island)
ABSTRACT	A data storage architecture is composed of an array of a flash memory solid state disk and a hard disk drive or any nonvolatile random access storage that are intelligently coupled by an intelligent processing unit such as a multi-core graphic processing unit. The solid state disk stores seldom-changed and mostly read reference data blocks while the hard disk drive stores compressed deltas between currently accessed I/O blocks and their corresponding reference blocks in the solid state disk so that random writes are not performed on the solid state disk during online I/O operations. The solid state disk and hard disk drive are controlled by the intelligent processing unit, which carries out high speed computations including similarity detection and delta compression/decompression. The architecture exploits the fast read performance of solid state disks and the high speed computation of graphic processing units to replace mechanical operations on hard disk drives while avoiding slow and wearing solid state drive writes.
FILED	Monday, April 19, 2010
APPL NO	12/762993
ART UNIT	2136 — Memory Access and Control
CURRENT CPC	Electric Digital Data Processing G06F 3/068 (20130101) G06F 3/0611 (20130101) G06F 3/0613 (20130101) G06F 3/0616 (20130101) G06F 3/0659 (20130101) G06F 12/0868 (20130101) Original (OR) Class G06F 2212/214 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/1225 (20130101)
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09177229 — Kalman filter approach to augment object tracking

US 09177229	Merler et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Information and Intelligent Systems (IIS)
APPLICANT(S)	The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S)	Michele Merler (New York, New York); John R. Kender (Leonia, New Jersey)
ABSTRACT	Techniques for tracking one or more objects at each position in an interval in a video input with the use of a Kalman filter, including obtaining a first location estimate of an object with an object detector, obtaining a second location estimate and a movement estimate of the object with an object tracker, determining a final estimate of a position and/or a velocity of the object with the Kalman filter.
FILED	Wednesday, August 07, 2013
APPL NO	13/961610
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/64 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/208 (20130101) G06T 2207/10016 (20130101) G06T 2207/20076 (20130101) G06T 2207/30241 (20130101)
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09177774 — Continuous flow mobility classifier interface with mass spectrometer

US 09177774	Brunelli et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	Nicholas Brunelli (Atlanta, Georgia); Konstantinos P. Giapis (Pasadena, California); Richard C. Flagan (Pasadena, California); Jesse L. Beauchamp (La Canada Flintridge, California); Evan Neidholdt (Glendale, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Nicholas Brunelli (Atlanta, Georgia); Konstantinos P. Giapis (Pasadena, California); Richard C. Flagan (Pasadena, California); Jesse L. Beauchamp (La Canada Flintridge, California); Evan Neidholdt (Glendale, California)
ABSTRACT	A continuous flow mobility classifier provide the ability to perform two-dimensional separation in mass spectrometry. An ionization system is used to ionize a sample. A differential mobility analyzer (DMA) (e.g., a nano-radial DMA) is coupled to the ionization system and to a mass spectrometer. The nano-RDMA is configured to separate the ionized sample by mobility for subsequent mass analysis by the mass spectrometer.
FILED	Tuesday, January 18, 2011
APPL NO	13/008697
ART UNIT	2881 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/624 (20130101) G01N 30/7233 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/165 (20130101) Original (OR) Class
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09178261 — Vertical microcoaxial interconnects

US 09178261	Boone et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Justin Boone (Lutz, Florida); Subramanian Krishnan (Wesley Chapel, Florida); Shekhar Bhansali (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Justin Boone (Lutz, Florida); Subramanian Krishnan (Wesley Chapel, Florida); Shekhar Bhansali (Tampa, Florida)
ABSTRACT	In one embodiment, a vertical microcoaxial interconnect includes a dielectric substrate having a top side and a bottom side, an inner conductor extending through the substrate from its top side to its bottom side, an outer conductor that extends through the substrate from its top side to its bottom side, the outer conductor surrounding the inner conductor, a signal line extending to the inner conductor without contacting the outer conductor, and a ground line extending to the outer conductor without contacting the inner conductor or the signal line.
FILED	Monday, October 07, 2013
APPL NO	14/047191
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/085 (20130101) Original (OR) Class
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09179047 — Systems and methods for estimating the structure and motion of an object

US 09179047	Dani et al.
FUNDED BY	Department of Energy (DOE) National Science Foundation (NSF)
APPLICANT(S)	Ashwin P. Dani (Urbana, Illinois); Warren Dixon (Gainesville, Florida)
ASSIGNEE(S)	University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S)	Ashwin P. Dani (Urbana, Illinois); Warren Dixon (Gainesville, Florida)
ABSTRACT	In one embodiment, the structure and motion of a stationary object are determined using two images and a linear velocity and linear acceleration of a camera. In another embodiment, the structure and motion of a stationary or moving object are determined using an image and linear and angular velocities of a camera.
FILED	Wednesday, June 13, 2012
APPL NO	14/126148
ART UNIT	2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/24 (20130101) Image Data Processing or Generation, in General G06T 7/0065 (20130101) G06T 7/2033 (20130101) G06T 2207/10032 (20130101) G06T 2207/30244 (20130101) Pictorial Communication, e.g Television H04N 5/225 (20130101) Original (OR) Class
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09179470 — Method for selecting state of a reconfigurable antenna in a communication system via machine learning

US 09179470	Gulati et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Nikhil Gulati (Philadelphia, Pennsylvania); David Gonzalez (Annandale, New Jersey); Kapil R. Dandekar (Philadelphia, Pennsylvania)
ASSIGNEE(S)	Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S)	Nikhil Gulati (Philadelphia, Pennsylvania); David Gonzalez (Annandale, New Jersey); Kapil R. Dandekar (Philadelphia, Pennsylvania)
ABSTRACT	A method for selecting the state of a reconfigurable antenna installed at either the receiver or transmitter of a communication system is provided. The proposed method uses online learning algorithm based on the theory of multi-armed bandit to perform antenna state selection. The selection technique utilizes the Post-Processing Signal-to-Noise Ratio (PPSNR) as a reward metric and maximizes the long-term average reward over time. The performance of the learning based selection technique is empirically evaluated using wireless channel data. The data is collected in an indoor environment using a 2×2 MIMO OFDM system employing highly directional metamaterial Reconfigurable Leaky Wave Antennas. The learning based selection technique shows performance improvements in terms of average PPSNR and regret over conventional heuristic policies.
FILED	Wednesday, December 10, 2014
APPL NO	14/565665
ART UNIT	2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Antennas, i.e Radio Aerials H01Q 1/007 (20130101) H01Q 13/20 (20130101) Transmission H04B 1/44 (20130101) Wireless Communication Networks H04W 24/02 (20130101) H04W 72/085 (20130101) Original (OR) Class
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Department of Agriculture (USDA)

09174387 — Microchannel reactors and fabrication processes

US 09174387	Luzenski et al.
FUNDED BY	Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Robert Luzenski (Marysville, Ohio); Jeffery Slane (Galloway, Ohio); Thomas Yuschak (Lewis Center, Ohio); Paul Neagle (Westerville, Ohio); Michael Marchiando (London, Ohio)
ASSIGNEE(S)	Velocys, Inc. (Plain City, Ohio)
INVENTOR(S)	Robert Luzenski (Marysville, Ohio); Jeffery Slane (Galloway, Ohio); Thomas Yuschak (Lewis Center, Ohio); Paul Neagle (Westerville, Ohio); Michael Marchiando (London, Ohio)
ABSTRACT	A method of loading material within a microchannel device, the method comprising: (a) loading particulates into a plurality of microchannels; and, (b) ultrasonically packing the particulates into the plurality of microchannels using a portable, compact ultrasonic densification unit.
FILED	Thursday, July 19, 2012
APPL NO	13/553518
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/0015 (20130101) B01J 8/16 (20130101) B01J 8/18 (20130101) B01J 8/1881 (20130101) B01J 19/0093 (20130101) B01J 2219/00783 (20130101) B01J 2219/00806 (20130101) B01J 2219/00817 (20130101) B01J 2219/00835 (20130101) B01J 2219/00844 (20130101) B01J 2219/00873 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 2200/0647 (20130101) B01L 2400/0436 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 67/00 (20130101) Original (OR) Class
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09174850 — Gaseous ammonia removal method

US 09174850	Szogi et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Ariel A Szogi (Florence, South Carolina); Matias B Vanotti (Florence, South Carolina); Michael J Rothrock (Athens, Georgia)
ABSTRACT	A system and method for passive capture of ammonia in an enclosure containing material that gives off ammonia. The invention allows for the passage of gaseous NH₃through microporous hydrophobic gas-permeable membranes and its capture in a circulated acidic solution with concomitant production of a concentrated non-volatile ammonium salt.
FILED	Thursday, October 30, 2014
APPL NO	14/528614
ART UNIT	1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Separation B01D 53/22 (20130101) B01D 2251/50 (20130101) B01D 2251/70 (20130101) B01D 2257/406 (20130101) B01D 2258/06 (20130101) B01D 2258/0266 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/12 (20130101) C01C 1/28 (20130101) Original (OR) Class C01C 1/164 (20130101) C01C 1/185 (20130101) C01C 1/242 (20130101) Acyclic or Carbocyclic Compounds C07C 51/412 (20130101) C07C 51/412 (20130101) C07C 51/412 (20130101) C07C 51/412 (20130101) C07C 55/07 (20130101) C07C 59/08 (20130101) C07C 59/265 (20130101)
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09175049 — Recombinant mycobacterium avium subsp. paratuberculosis proteins induce immunity and protect against infection

US 09175049	Stabel et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Judith R. Stabel (Ames, Iowa); John P. Bannantine (Ames, Iowa)
ABSTRACT	Compositions of immunogenic proteins of Mycobacterium avium subspecies paratuberculosis (MAP) are effective for stimulating a protective immune response in animals against MAP. Combinations of MAP1087 with two or more of MAP1204, MAP1272c and MAP2077c are effective for stimulating a protective immune response in animals against MAP and can be administered as vaccines against paratuberculosis (Johne's disease). Induction of the immune response significantly reduces or eliminates colonization of the animal by MAP, and consequently reduces or eliminates the symptoms of clinical disease in animals infected with MAP and reduces or eliminates fecal shedding of MAP. Vaccination with the compositions provides protection against clinical disease and reduces transmission of MAP infection within a herd.
FILED	Thursday, September 26, 2013
APPL NO	14/038077
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 2039/552 (20130101) A61K 2039/6068 (20130101) Peptides C07K 14/35 (20130101) Original (OR) Class
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09176110 — Method of determining histamine concentration in fish

US 09176110	Kim et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Moon S. Kim (Silver Spring, Maryland); Kuanglin Chao (Ellicott, Maryland); David P. Bannon (Hopkinton, Massachusetts)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); Headwall Photonics, Inc. (Fitchburg, Massachusetts)
INVENTOR(S)	Moon S. Kim (Silver Spring, Maryland); Kuanglin Chao (Ellicott, Maryland); David P. Bannon (Hopkinton, Massachusetts)
ABSTRACT	A histamine concentration level of a fish item is determined by illuminating the fish and analyzing the resulting spectral image data. Specifically, an algorithm is applied to the fish image data so that a histamine concentration value is calculated for every pixel of the fish image. A corresponding histamine concentration image of the fish is produced based on the collective histamine concentration values. The fish is accepted or rejected based on the collective histamine concentration values and/or the histamine concentration image. The histamine concentration image may be used to identify specific parts of a fish fillet that exceed (or do not exceed) a predetermined histamine concentration level.
FILED	Friday, September 13, 2013
APPL NO	14/026684
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) Original (OR) Class
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Department of Commerce (DOC)

09174187 — Water-dispersable nanoparticles

US 09174187	Tulsky et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST)
APPLICANT(S)	Eric Tulsky (Berkeley, California); Kari Haley (Eugene, Oregon); Imad Naasani (Manchester, United Kingdom); John Mauro (Eugene, Oregon); Roman Rozhkov (Eugene, Oregon); Joseph A. Treadway (Eugene, Oregon)
ASSIGNEE(S)	Life Technologies Corporation (Carlsbad, California)
INVENTOR(S)	Eric Tulsky (Berkeley, California); Kari Haley (Eugene, Oregon); Imad Naasani (Manchester, United Kingdom); John Mauro (Eugene, Oregon); Roman Rozhkov (Eugene, Oregon); Joseph A. Treadway (Eugene, Oregon)
ABSTRACT	Provided herein are methods for making water-soluble nanoparticles comprising a core/shell nanocrystal that is coated with a surface layer comprising enough hydrophilic ligands to render the nanoparticle water soluble or water dispersable. Methods for crosslinking molecules on the surface of a nanoparticle, which methods can be used on the above water-soluble nanoparticles also are provided. Nanoparticle compositions resulting from these methods are also provided.
FILED	Thursday, August 06, 2009
APPL NO	13/057504
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) Original (OR) Class Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) B22F 1/0022 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/81 (20130101) Y10S 977/773 (20130101) Y10S 977/834 (20130101) Y10S 977/902 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09174189 — Apparatus and method for ultrasound treatment for ballast water management

US 09174189	Wu et al.
FUNDED BY	Department of Commerce (DOC) National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S)	Mei-Yin Wu (Princeton, New Jersey); Jun-Ru Wu (South Burlington, Vermont)
ASSIGNEE(S)	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York); UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (Burlington, Vermont); MONTCLAIR STATE UNIVERSITY (Montclair, New Jersey)
INVENTOR(S)	Mei-Yin Wu (Princeton, New Jersey); Jun-Ru Wu (South Burlington, Vermont)
ABSTRACT	The invention provides a method of treating a target area with an ultrasound wave pattern, including: providing an ultrasound apparatus having an ultrasound wave generator operatively attached to a plurality of transducers, coupled to an immersible support and configured to emit an ultrasound wave; immersing the apparatus into a water environment; positioning the apparatus proximate to a target area to treat at least one in situ organism; and emitting a pattern of ultrasound waves from the transducers, the pattern of ultrasound waves additive in effect and emitted onto the target area to threat an in situ underwater organism.
FILED	Monday, November 21, 2011
APPL NO	13/301367
ART UNIT	1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/10 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/36 (20130101) C02F 1/50 (20130101) C02F 2103/008 (20130101) C02F 2103/42 (20130101) C02F 2209/005 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09175131 — Deoxybenzoin-derived anti-flammable polymers

US 09175131	Emrick et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Transportation (USDOT) Federal Aviation Administration (FAA)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Todd Emrick (South Deerfield, Massachusetts); E. Bryan Coughlin (Amherst, Massachusetts); Thangamani Ranganathan (San Jose, California); Michael Beaulieu (Chicopee, Massachusetts); Richard Farris (Leeds, Massachusetts); Bon-Cheol Ku (Wanju-gun, South Korea)
ABSTRACT	The invention provides novel flame-retardant polymers and materials, their synthesis and use. More particularly, the flame-retardant polymers are deoxybenzoin-derived polymers.
FILED	Thursday, October 18, 2012
APPL NO	13/655123
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/22 (20130101) C08F 12/32 (20130101) C08F 20/18 (20130101) C08F 212/08 (20130101) C08F 212/08 (20130101) C08F 212/14 (20130101) C08F 212/14 (20130101) C08F 212/32 (20130101) C08F 212/32 (20130101) C08F 2220/302 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/771 (20130101) C08G 18/3215 (20130101) C08G 18/6674 (20130101) C08G 18/7621 (20130101) C08G 18/7671 (20130101) C08G 59/04 (20130101) C08G 59/06 (20130101) C08G 59/50 (20130101) C08G 59/504 (20130101) C08G 61/04 (20130101) Original (OR) Class C08G 2101/0008 (20130101)
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Department of Veterans Affairs (DVA)

09173917 — Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug

US 09173917	Nagasawa et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Herbert T. Nagasawa (Richfield, Minnesota); Jonathan F. Cohen (Prior Lake, Minnesota)
ASSIGNEE(S)	Max International, LLC (Salt Lake City, Utah); The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S)	Herbert T. Nagasawa (Richfield, Minnesota); Jonathan F. Cohen (Prior Lake, Minnesota)
ABSTRACT	The present invention relates to compositions and methods for reducing oxidative stress in a cell, increasing glutathione levels in a cell, increasing L-cysteine levels in a cell and reducing hepatocytotoxicity by contacting a cell with a sulfhydryl protected glutathione prodrug or a sulfhydryl protected cysteine prodrug.
FILED	Thursday, July 12, 2012
APPL NO	13/547430
ART UNIT	1675 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/063 (20130101) Original (OR) Class
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09173930 — Methods for detecting a mycobacterium tuberculosis infection

US 09173930	Lewinsohn et al.
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	David M. Lewinsohn (Portland, Oregon); Deborah A. Lewinsohn (Portland, Oregon)
ASSIGNEE(S)	Oregon Health and Science University (Portland, Oregon); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	David M. Lewinsohn (Portland, Oregon); Deborah A. Lewinsohn (Portland, Oregon)
ABSTRACT	Methods for detecting an infection with Mtb in a subject are disclosed. The methods include detecting the presence of CD8⁺ T cells that specifically recognize an Mtb polypeptide. The methods include in vitro assays for detecting the presence of CD8⁺ T cells in a biological sample, and in vivo assays that detect a delayed type hypersensitivity reaction. The methods also include detecting Mtb polypeptides and polynucleotides.
FILED	Friday, November 19, 2010
APPL NO	13/510869
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 49/00 (20130101)
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09176122 — Biomarkers for predicting response to immunosuppressive therapy

US 09176122	Burnette
FUNDED BY	Department of Veterans Affairs (DVA) Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Pearlie K. Burnette (Tampa, Florida)
ASSIGNEE(S)	UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S)	Pearlie K. Burnette (Tampa, Florida)
ABSTRACT	The subject invention concerns methods and materials for assessing a patient's likelihood of responsiveness to an immunosuppressive therapy. The subject invention is contemplated for use with patients having an autoimmune disorder. In an exemplified embodiment, the methods of the invention are used for assessing and/or treating a patient with MDS. In one embodiment, a method of the invention comprises analyzing T cells of a patient for dysregulation of CD4⁺ and/or CD8⁺ T cell subsets, and determining the patient's likelihood of responsiveness to IST based on the level of dysregulation of the patient's CD4⁺ and/or CD8⁺ T cell subsets. In one embodiment, an increased likelihood of patient responsiveness to IST is associated with an increased percentage of CD4⁺ and/or CD8⁺ effector memory T cells and/or terminal effector memory T cells for a patient. The subject invention also concerns methods for treating a patient with an autoimmune disorder, such as MDS. In one embodiment, a method of the invention comprises determining if a patient is likely to respond to IST, wherein said determination is made using a method of the present invention for assessing likelihood of responsiveness to IST; and if the patient is determined to be one likely to respond to IST, administering an effective regimen of IST to the patient.
FILED	Tuesday, March 24, 2009
APPL NO	12/933975
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5094 (20130101) Original (OR) Class G01N 33/6875 (20130101) G01N 33/57426 (20130101) G01N 2333/70564 (20130101) G01N 2333/70589 (20130101) G01N 2800/22 (20130101) G01N 2800/52 (20130101)
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National Aeronautics and Space Administration (NASA)

09175322 — Stable bacterial cultures for producing alginates

US 09175322	Yu et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Ames Research Center (ARC)
APPLICANT(S)	Hongwei D. Yu (Huntington, West Virginia); Dongru Qiu (Norman, Oklahoma); F. Heath Damron (Huntington, West Virginia)
ASSIGNEE(S)	Marshall University Research Corporation (Huntington, West Virginia)
INVENTOR(S)	Hongwei D. Yu (Huntington, West Virginia); Dongru Qiu (Norman, Oklahoma); F. Heath Damron (Huntington, West Virginia)
ABSTRACT	Methods for mass producing bacterial alginate, bacterial cultures for producing alginate, and pharmaceutical compositions containing bacterial alginate are contemplated.
FILED	Wednesday, April 29, 2009
APPL NO	12/432474
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) Original (OR) Class
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09176504 — High-speed on demand droplet generation and single cell encapsulation driven by induced cavitation

US 09176504	Chiou et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Aeronautics and Space Administration (NASA) National Science Foundation (NSF)
APPLICANT(S)	Pei-Yu Chiou (Los Angeles, California); Ting-Hsiang S. Wu (Los Angeles, California); Sung-Yong Park (Thousand Oaks, California); Michael A. Teitell (Tarzana, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Pei-Yu Chiou (Los Angeles, California); Ting-Hsiang S. Wu (Los Angeles, California); Sung-Yong Park (Thousand Oaks, California); Michael A. Teitell (Tarzana, California)
ABSTRACT	Methods and devices for the formation of droplets of a first fluid in a second fluid and the encapsulation of particles or cells within such droplets are disclosed. Impetus for droplet formation is provided by the creation of a transient bubble, which may be induced using a pulsed laser. Droplet volume and the frequency at which droplets are formed can be controlled by modulation of the pulsed laser. The disclosed methods and devices are particularly suitable for use in microfluidic devices.
FILED	Thursday, February 09, 2012
APPL NO	13/370196
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 21/64 (20130101) G01N 29/2418 (20130101) G01N 2015/1481 (20130101) G01N 2291/02433 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 11/13 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/2496 (20150401)
VIEW PATENT	@ USPTO: Full Text PDF

09177270 — Engineering review information system

US 09177270	Grems, III et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Edward G. Grems, III (Vienna, Virginia); James E. Henze (Cocoa Beach, Florida); Jonathan A. Bixby (Titusville, Florida); Mark Roberts (Annapolis, Maryland); Thomas Mann (Bowie, Maryland)
ASSIGNEE(S)	A.I. SOLUTIONS, INC. (Lanham, Maryland)
INVENTOR(S)	Edward G. Grems, III (Vienna, Virginia); James E. Henze (Cocoa Beach, Florida); Jonathan A. Bixby (Titusville, Florida); Mark Roberts (Annapolis, Maryland); Thomas Mann (Bowie, Maryland)
ABSTRACT	A disciplinal engineering review computer information system and method by defining a database of disciplinal engineering review process entities for an enterprise engineering program, opening a computer supported engineering item based upon the defined disciplinal engineering review process entities, managing a review of the opened engineering item according to the defined disciplinal engineering review process entities, and closing the opened engineering item according to the opened engineering item review.
FILED	Friday, June 30, 2006
APPL NO	11/428016
ART UNIT	2168 — Data Bases & File Management
CURRENT CPC	Electric Digital Data Processing G06F 17/50 (20130101) G06F 17/60 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06 (20130101) Original (OR) Class G06Q 10/06311 (20130101) G06Q 10/063118 (20130101)
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Office of the Director of National Intelligence (ODNI)

09177130 — Facial feature detection

US 09177130	Nechyba et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Research, Development and Engineering Command (RDECOM) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	Michael Christian Nechyba (Pittsburgh, Pennsylvania); Michael Andrew Sipe (Pittsburgh, Pennsylvania)
ASSIGNEE(S)	Google Inc. (Mountain View, California)
INVENTOR(S)	Michael Christian Nechyba (Pittsburgh, Pennsylvania); Michael Andrew Sipe (Pittsburgh, Pennsylvania)
ABSTRACT	An example method includes capturing, by a camera of a computing device, an image including at least a face of a user, calculating a face template of the face of the user in the image, and analyzing the face template to determine whether the face includes at least one of a removable facial feature that decreases a level of distinctiveness between two faces and a non-removable facial feature that decreases a level of distinctiveness between two faces. When the face includes the removable facial feature, the method further includes outputting a notification for the user to remove the removable facial feature. When the face includes the non-removable facial feature, the method further includes adjusting a first similarity score threshold to a second similarity score threshold.
FILED	Tuesday, January 08, 2013
APPL NO	13/736760
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Electric Digital Data Processing G06F 21/32 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00221 (20130101) G06K 9/6217 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178704 — Input consistency verification for server assisted secure function evaluation

US 09178704	Kolesnikov et al.
FUNDED BY	Department of the Interior (DOI) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	Alcatel-Lucent USA Inc. (Murray Hill, New Jersey)
ASSIGNEE(S)	Alcatel Lucent (Boulogne-Billancourt, France)
INVENTOR(S)	Vladimir Y. Kolesnikov (Jersey City, New Jersey); Ranjit Kumaresan (College Park, Maryland); Abdullatif Shikfa (Villebon-sur-Yvette, France)
ABSTRACT	Server-assisted secure function evaluation (SFE) is performed with input consistency verification for two parties that want to evaluate a function. The server computes a garbled circuit corresponding to the function. A predefined bit of the 0-secret of wire i in the garbled circuit is set to a random bit b_iand a predefined bit of the 1-secret of wire i in the garbled circuit is set to b_i. The server communicates with each party using an Oblivious Transfer (OT) to provide encrypted versions of the respective inputs of each party. Each party receives the encrypted wire secret of the other party and the garbled circuit for computation of a respective output and stores the predefined bit of a wire of interest of the other party. A given party can verify input consistency by the other party over at least two executions by comparing the values stored by the given party for the at least two executions with corresponding values obtained from the server.
FILED	Friday, September 28, 2012
APPL NO	13/630533
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) Original (OR) Class H04L 9/3218 (20130101) H04L 2209/12 (20130101) H04L 2209/46 (20130101) H04L 2209/50 (20130101)
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U.S. State Government

09173862 — Methods and compositions for treating and identifying compounds to treat age-related macular degeneration

US 09173862	McKay et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) U.S. State Government State of Arizona
APPLICANT(S)	Brian McKay (Marana, Arizona); John A. Martens (Tucson, Arizona)
ASSIGNEE(S)	Arizona Board of Regents, a Body Corporate of the State of Arizona, Acting for and on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S)	Brian McKay (Marana, Arizona); John A. Martens (Tucson, Arizona)
ABSTRACT	The present invention provides methods for treating or limiting development of age-related macular degeneration, as well as methods for identifying compound suitable for such use.
FILED	Friday, April 17, 2009
APPL NO	12/937669
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/07 (20130101) A61K 31/07 (20130101) A61K 31/195 (20130101) Original (OR) Class A61K 31/195 (20130101) A61K 31/355 (20130101) A61K 31/355 (20130101) A61K 31/375 (20130101) A61K 31/375 (20130101) A61K 33/30 (20130101) A61K 33/30 (20130101) A61K 33/34 (20130101) A61K 33/34 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09175041 — Crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline, and methods for preparing dolamethylleuine and dolaphenvaline

US 09175041	Pettit et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) U.S. State Government State of Arizona
APPLICANT(S)	George R. Pettit (Paradise Valley, Arizona); Thomas Smith (Tempe, Arizona); Jun-Ping Xu (Chandler, Arizona); Delbert Herald (Tempe, Arizona)
ASSIGNEE(S)	Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S)	George R. Pettit (Paradise Valley, Arizona); Thomas Smith (Tempe, Arizona); Jun-Ping Xu (Chandler, Arizona); Delbert Herald (Tempe, Arizona)
ABSTRACT	The present invention relates to the crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline. The present invention also relates to processes for preparing dolamethylleuine and dolaphenvaline. The present invention further relates to computer readable medium with crystal structural data and/or information stored thereon.
FILED	Wednesday, April 25, 2012
APPL NO	14/113682
ART UNIT	1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Acyclic or Carbocyclic Compounds C07C 227/18 (20130101) Peptides C07K 5/0205 (20130101) C07K 7/54 (20130101) Original (OR) Class Electric Digital Data Processing G06F 19/701 (20130101)
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Department of Transportation (USDOT)

09175131 — Deoxybenzoin-derived anti-flammable polymers

US 09175131	Emrick et al.
FUNDED BY	Department of Commerce (DOC) National Institute of Standards and Technology (NIST) Department of Transportation (USDOT) Federal Aviation Administration (FAA)
APPLICANT(S)	University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	University of Massachusetts (Boston, Massachusetts)
INVENTOR(S)	Todd Emrick (South Deerfield, Massachusetts); E. Bryan Coughlin (Amherst, Massachusetts); Thangamani Ranganathan (San Jose, California); Michael Beaulieu (Chicopee, Massachusetts); Richard Farris (Leeds, Massachusetts); Bon-Cheol Ku (Wanju-gun, South Korea)
ABSTRACT	The invention provides novel flame-retardant polymers and materials, their synthesis and use. More particularly, the flame-retardant polymers are deoxybenzoin-derived polymers.
FILED	Thursday, October 18, 2012
APPL NO	13/655123
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 12/22 (20130101) C08F 12/32 (20130101) C08F 20/18 (20130101) C08F 212/08 (20130101) C08F 212/08 (20130101) C08F 212/14 (20130101) C08F 212/14 (20130101) C08F 212/32 (20130101) C08F 212/32 (20130101) C08F 2220/302 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/771 (20130101) C08G 18/3215 (20130101) C08G 18/6674 (20130101) C08G 18/7621 (20130101) C08G 18/7671 (20130101) C08G 59/04 (20130101) C08G 59/06 (20130101) C08G 59/50 (20130101) C08G 59/504 (20130101) C08G 61/04 (20130101) Original (OR) Class C08G 2101/0008 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Department of the Interior (DOI)

09178704 — Input consistency verification for server assisted secure function evaluation

US 09178704	Kolesnikov et al.
FUNDED BY	Department of the Interior (DOI) Office of the Director of National Intelligence (ODNI) Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S)	Alcatel-Lucent USA Inc. (Murray Hill, New Jersey)
ASSIGNEE(S)	Alcatel Lucent (Boulogne-Billancourt, France)
INVENTOR(S)	Vladimir Y. Kolesnikov (Jersey City, New Jersey); Ranjit Kumaresan (College Park, Maryland); Abdullatif Shikfa (Villebon-sur-Yvette, France)
ABSTRACT	Server-assisted secure function evaluation (SFE) is performed with input consistency verification for two parties that want to evaluate a function. The server computes a garbled circuit corresponding to the function. A predefined bit of the 0-secret of wire i in the garbled circuit is set to a random bit b_iand a predefined bit of the 1-secret of wire i in the garbled circuit is set to b_i. The server communicates with each party using an Oblivious Transfer (OT) to provide encrypted versions of the respective inputs of each party. Each party receives the encrypted wire secret of the other party and the garbled circuit for computation of a respective output and stores the predefined bit of a wire of interest of the other party. A given party can verify input consistency by the other party over at least two executions by comparing the values stored by the given party for the at least two executions with corresponding values obtained from the server.
FILED	Friday, September 28, 2012
APPL NO	13/630533
ART UNIT	2435 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 9/32 (20130101) Original (OR) Class H04L 9/3218 (20130101) H04L 2209/12 (20130101) H04L 2209/46 (20130101) H04L 2209/50 (20130101)
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European Union (EU)

09177491 — Sealing device

US 09177491	Azzalin et al.
FUNDED BY	European Union (EU)
APPLICANT(S)	Graziano Azzalin (Oleggio, Italy); Marco Sironi (Laveno Mombello, Italy); Marcello Barboni (Genoa, Italy); Paolo Timossi (Arquata Scrivia, Italy)
ASSIGNEE(S)	THE EUROPEAN UNION, REPRESENTED BY THE EUROPEAN COMMISSION (, Belgium)
INVENTOR(S)	Graziano Azzalin (Oleggio, Italy); Marco Sironi (Laveno Mombello, Italy); Marcello Barboni (Genoa, Italy); Paolo Timossi (Arquata Scrivia, Italy)
ABSTRACT	A sealing device including a housing and a closure member having a first end and a second end, at least one of the first and second ends being removably attached to the housing, the housing having means for checking the integrity of the closure member and a first transponder for transmitting information on the status of the sealing device where, the sealing device further includes a second transponder, preferably a passive transponder, associated with at least one of the first and second ends (16, 20) of the closure member, the second transponder comprising a second identity, and a transponder reader associated with the first transponder, preferably an active transponder, the transponder reader being arranged for reading the second identity of the second transponder; the first transponder being configured for receiving the second identity from the transponder reader and for transmitting the second identity.
FILED	Thursday, October 29, 2009
APPL NO	13/130598
ART UNIT	2685 — Selective Communication
CURRENT CPC	Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 3/0329 (20130101) Original (OR) Class G09F 3/0335 (20130101) G09F 3/0358 (20130101) G09F 3/0376 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

09177547 — System and method for processing speech to identify keywords or other information

US 09177547	Kintzley et al.
FUNDED BY	Department of Defense (DOD) National Security Agency (NSA)
APPLICANT(S)	Keith Kintzley (Severna Park, Maryland); Aren Jansen (Ellicott City, Maryland); Hynek Hermansky (Baltimore, Maryland); Kenneth Church (Croton-on-Hudson, New York)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Keith Kintzley (Severna Park, Maryland); Aren Jansen (Ellicott City, Maryland); Hynek Hermansky (Baltimore, Maryland); Kenneth Church (Croton-on-Hudson, New York)
ABSTRACT	A system and method are provided for performing speech processing. A system includes an audio detection system configured to receive a signal including speech and a memory having stored therein a database of keyword models forming an ensemble of filters associated with each keyword in the database. A processor is configured to receive the signal including speech from the audio detection system, decompose the signal including speech into a sparse set of phonetic impulses, and access the database of keywords and convolve the sparse set of phonetic impulses with the ensemble of filters. The processor is further configured to identify keywords within the signal including speech based a result of the convolution and control operation the electronic system based on the keywords identified.
FILED	Tuesday, June 25, 2013
APPL NO	13/926659
ART UNIT	2657 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC	Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/14 (20130101) Original (OR) Class G10L 15/22 (20130101) G10L 2015/085 (20130101) G10L 2015/088 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

09173994 — Touch-actuated micropump for transdermal drug delivery and method of use

US 09173994	Ziaie et al.
FUNDED BY
APPLICANT(S)	Babak Ziaie (West Lafayette, Indiana); Manuel Ochoa (West Lafayette, Indiana); Charilaos Mousoulis (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Babak Ziaie (West Lafayette, Indiana); Manuel Ochoa (West Lafayette, Indiana); Charilaos Mousoulis (West Lafayette, Indiana)
ABSTRACT	A micropump device. The micropump device includes a first layer forming a first chamber configured to store a working material, a second chamber defined by a deflectable membrane in fluid communication with the first chamber and configured to deflect in response to a pressure increase in the first chamber in response to a volume increase in the first chamber, the second chamber configured to store a drug compound to be delivered to a subject's vascular system, and at least one needle in fluid communication with the second chamber and configured to penetrate a subject's skin to pump the drug compound in response to the deflection of the deflectable membrane.
FILED	Monday, August 22, 2011
APPL NO	13/214990
ART UNIT	3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC	Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14248 (20130101) Original (OR) Class A61M 5/14586 (20130101) A61M 5/14593 (20130101) A61M 2037/003 (20130101) A61M 2037/0023 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09175079 — Depletion of teratoma-forming pluripotent stem cells

US 09175079	Tang et al.
FUNDED BY
APPLICANT(S)	Chad Tang (East Palo Alto, California); Irving L. Weissman (Stanford, California); Micha Drukker (Stanford, California)
ASSIGNEE(S)	THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S)	Chad Tang (East Palo Alto, California); Irving L. Weissman (Stanford, California); Micha Drukker (Stanford, California)
ABSTRACT	Compositions and methods are provided for depletion of pluripotent cells. In one embodiment of the invention, methods are provided for depletion of pluripotent cells from a mixed population of differentiated cells and stem cells, to provide a population of cells substantially free of pluripotent stem cells. Monoclonal antibodies useful in depletion and in identification of pluripotent stem cells are also provided.
FILED	Friday, January 28, 2011
APPL NO	13/575511
ART UNIT	1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/28 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09177721 — Electrochemical devices and methods of fabrication

US 09177721	Amatucci et al.
FUNDED BY
APPLICANT(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (Newark, New Jersey)
ASSIGNEE(S)	Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S)	Glenn G. Amatucci (Peapack, New Jersey); Irene Plitz (Toms River, New Jersey); Anna B. Halajko (Parlin, New Jersey); Linda Wu Sung (Millburn, New Jersey)
ABSTRACT	The described invention provides a packaged electrochemical device comprising an electrochemical battery, further comprising at least one electrochemical cell stack and a barrier packaging material. The present invention further provides a method of fabricating the packaged electrochemical device. The present invention further provides a flexible multifunctional liquid-based thermogalvanic cell that converts and stores electricity derived from low grade temperature differentials that exist in ubiquitous scenarios.
FILED	Thursday, March 14, 2013
APPL NO	13/826343
ART UNIT	1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 2/103 (20130101) Original (OR) Class H01G 9/145 (20130101) H01G 11/62 (20130101) H01G 11/68 (20130101) H01G 11/80 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/026 (20130101) H01M 2/0262 (20130101) H01M 2/0287 (20130101) H01M 10/058 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09178153 — Memristor structure with a dopant source

US 09178153	Zhang et al.
FUNDED BY
APPLICANT(S)	Minxian Max Zhang (Mountain View, California); Jianhua Yang (Palo Alto, California); R. Stanley Williams (Portola Valley, California)
ASSIGNEE(S)	Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S)	Minxian Max Zhang (Mountain View, California); Jianhua Yang (Palo Alto, California); R. Stanley Williams (Portola Valley, California)
ABSTRACT	A memristor including a dopant source is disclosed. The structure includes an electrode, a conductive alloy including a conducting material, a dopant source material, and a dopant, and a switching layer positioned between the electrode and the conductive alloy, wherein the switching layer includes an electronically semiconducting or nominally insulating and weak ionic switching material. A method for fabricating the memristor including a dopant source is also disclosed.
FILED	Wednesday, July 20, 2011
APPL NO	14/233075
ART UNIT	2899 — Semiconductors/Memory
CURRENT CPC	Static Stores G11C 13/0007 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/04 (20130101) H01L 45/08 (20130101) H01L 45/085 (20130101) H01L 45/142 (20130101) H01L 45/145 (20130101) H01L 45/146 (20130101) H01L 45/147 (20130101) H01L 45/1658 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 03, 2015.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2015/fedinvent-patents-20151103.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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