FedInvent™ Patents
Patent Details for Tuesday, April 26, 2016
This page was updated on Monday, March 27, 2023 at 04:46 AM GMT
Department of Defense (DOD)
| US 09320736 | Kutikov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Kutikov (Voorhees, New Jersey); Vladimir Kolenko (Philadelphia, Pennsylvania); Seth M. Cohen (San Marcos, California); Robert G. Uzzo (Ambler, Pennsylvania); Ervin Teper (Huntington Valley, Pennsylvania) |
| ABSTRACT | The invention provides zinc chelating agents and formulations thereof that deplete XIAP in cancer cells and sensitize the cells to apoptosis-inducing agents. The invention provides methods for sensitizing apoptosis-resistant cancer cells to apoptosis-inducing agents, as well as methods for treating a subject with a combined therapy of a zinc chelating agent and an apoptosis-inducing agent. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 14/610044 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Original (OR) Class A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 38/191 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320750 | Yaffe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael B. Yaffe (Somerville, Massachusetts); Michael Jungho Lee (Cambridge, Massachusetts); Paula T. Hammond (Newton, Massachusetts); Stephen W. Morton (Somerville, Massachusetts) |
| ABSTRACT | Time-staggered inhibition of EGFR, in combination with DNA damaging agents, is a useful therapeutic strategy for treating cancers, particularly drug resistant cancers such as a subset of triple-negative tumors, particularly those with high basal levels of phosphorylated EGFR. The staggered therapy was also demonstrated to be applicable to other types of tumors, especially lung cancers, which contain either high levels of phosphorylated wild-type EGFR or mutations within EGFR itself. EGFR inhibition dramatically sensitizes cancer cells to DNA damage if the drugs are given sequentially, but not simultaneously. The first drug must be administered in a dosage and for a period of time sufficient for the dynamic network rewiring of an oncogenic signature maintained by active EGFR signaling to unmask an apoptotic process that involves activation of caspase-8. |
| FILED | Tuesday, April 23, 2013 |
| APPL NO | 13/869012 |
| ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/704 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320789 | Venkatesan et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army, on behalf of the Walter Reed Army Institute of Research (Washington, District of Columbia) |
| INVENTOR(S) | Malabi Venkatesan (Bethesda, Maryland); Ryan Ranallo (Gaithersburg, Maryland); Shoshana Barnoy (Rockville, Maryland) |
| ABSTRACT | Shigella vaccine strains whose primary attenuating feature is deletion of the virG(icsA) gene and additional two or more deletions in setAB(shET1), senA(shET2), senB(shET2-2), stxAB, and msbB2 genes. Thus, the vaccine strain will have three or more deletions in the identified genes, will be safer, and will reduce or eliminate symptoms of fever and diarrhea in humans. The following specific vaccine strains have been constructed: WRSS3 (ΔsenA, ΔsenB, ΔvirG, ΔmsbB2), WRSf2G15 (ΔvirG, ΔsetAB, ΔsenA, ΔsenB, ΔmsbB2), and WRSd5 (ΔvirG, ΔstxAB, ΔsenA, ΔsenB, ΔmsbB2). |
| FILED | Monday, February 23, 2015 |
| APPL NO | 14/628842 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0283 (20130101) Original (OR) Class A61K 2039/522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320810 | Ruoslahti et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| INVENTOR(S) | Erkki Ruoslahti (Rancho Santa Fe, California); Kimmo Porkka (Helsinki, Finland); Sven Christian (San Diego, California) |
| ABSTRACT | The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided. |
| FILED | Wednesday, October 30, 2013 |
| APPL NO | 14/067858 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48246 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) C07K 14/4702 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320815 | Kassis |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Amin I. Kassis (Chestnut Hill, Massachusetts) |
| ABSTRACT | The invention provides methods and compositions, e.g., for tumor imaging and therapy. |
| FILED | Monday, March 11, 2013 |
| APPL NO | 13/792966 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0459 (20130101) Original (OR) Class Heterocyclic Compounds C07D 239/74 (20130101) C07D 239/86 (20130101) C07D 239/91 (20130101) C07D 239/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321015 | Jayaweera et al. |
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| FUNDED BY |
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| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Indira Jayaweera (Menlo Park, California); Gopala N. Krishnan (Menlo Park, California); Angel Sanjurjo (Menlo Park, California); Palitha Jayaweera (Menlo Park, California); Srinivas Bhamidi (Menlo Park, California) |
| ABSTRACT | The invention provides methods for preparing an asymmetric hollow fiber, the asymmetric hollow fibers prepared by such methods, and uses of the asymmetric hollow fibers. One method involves passing a polymeric solution through an outer annular orifice of a tube-in-orifice spinneret, passing a bore fluid though an inner tube of the spinneret, dropping the polymeric solution and bore fluid through an atmosphere over a dropping distance, and quenching the polymeric solution and bore fluid in a bath to form an asymmetric hollow fiber. |
| FILED | Wednesday, February 26, 2014 |
| APPL NO | 14/190100 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 69/087 (20130101) Original (OR) Class B01D 71/62 (20130101) B01D 2256/16 (20130101) B01D 2257/502 (20130101) B01D 2257/504 (20130101) B01D 2257/7025 (20130101) B01D 2323/12 (20130101) B01D 2325/02 (20130101) B01D 2325/04 (20130101) B01D 2325/30 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/444 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/10 (20130101) Y02C 20/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321079 | Whitaker |
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| FUNDED BY |
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| APPLICANT(S) | George Whitaker (Bloomington, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | George Whitaker (Bloomington, Indiana) |
| ABSTRACT | A process for manufacturing a wave energy emitter and a system for manufacturing the same. |
| FILED | Tuesday, October 15, 2013 |
| APPL NO | 14/054355 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/10 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/221 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 13/1609 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 13/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49005 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09321081 — Apparatus and methods of tuning and amplifying piezoelectric sonic and ultrasonic outputs
| US 09321081 | Whitaker |
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| FUNDED BY |
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| APPLICANT(S) | George Whitaker (Bloomington, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | George Whitaker (Bloomington, Indiana) |
| ABSTRACT | An apparatus and method associated with amplifying piezoelectric sonic and ultrasonic outputs is presented which provides high power output from piezoelectric devices, especially at high ultrasonic frequencies, in open air, which mitigates or eliminates overheating of the piezoelectric devices when stimulated at or near their peak outputs for extended periods. In addition, the invention provides a means of amplifying a piezoelectric sonic and ultrasonic device if a desired output power exceeds a normal maximum capability of the piezoelectric device. |
| FILED | Wednesday, March 27, 2013 |
| APPL NO | 13/851336 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/06 (20130101) Original (OR) Class B06B 1/0207 (20130101) B06B 1/0618 (20130101) B06B 2201/20 (20130101) B06B 2201/55 (20130101) B06B 2201/71 (20130101) B06B 2201/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321128 | Bradley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Timothy Bradley (Loogootee, Indiana); Eric Hillenbrand (Evansville, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Timothy Bradley (Loogootee, Indiana); Eric Hillenbrand (Evansville, Indiana) |
| ABSTRACT | A modulation device for directing a mobile tracking device away from an asset is provided. The modulation device includes a continuous wave laser source whose output is directed at a seeker head of the mobile tracking device. The modulation device causes the generation of localized sources within the mobile tracking device and confuses the mobile tracking device as to the true location of the asset. A portable cutting device is disclosed. The portable cutting device may include a portable power supply and a laser source. The portable power supply and laser source of the portable cutting device may be positioned within a backpack and carried by a user. A handheld unit which is coupled to the laser source may be supported by the hands of the operator. The handheld unit provides power generated by the laser source to a barrier to be cut. |
| FILED | Friday, January 04, 2013 |
| APPL NO | 13/734397 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0096 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/708 (20130101) C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 13/0056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321238 | Bird et al. |
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| FUNDED BY |
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| APPLICANT(S) | Connie E. Bird (Rocky Hill, Connecticut); Alan R. Goodworth (Oxford, Connecticut); Thomas A. Carstensen (Shelton, Connecticut); Gary Hamilton (Middletown, Connecticut) |
| ASSIGNEE(S) | Sikorsky Aircraft Corporation (Stratford, Connecticut) |
| INVENTOR(S) | Connie E. Bird (Rocky Hill, Connecticut); Alan R. Goodworth (Oxford, Connecticut); Thomas A. Carstensen (Shelton, Connecticut); Gary Hamilton (Middletown, Connecticut) |
| ABSTRACT | An armor panel includes a multiple of pins which penetrate a first skin, a high molecular weight polyethylene fiber composite material layer and a second skin which integrates ballistic protection into load bearing structure. |
| FILED | Friday, September 02, 2011 |
| APPL NO | 13/224677 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/06 (20130101) Original (OR) Class B32B 3/08 (20130101) B32B 5/26 (20130101) B32B 7/08 (20130101) B32B 15/14 (20130101) B32B 15/20 (20130101) B32B 2260/046 (20130101) B32B 2262/0253 (20130101) B32B 2571/02 (20130101) B32B 2605/18 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 428/24008 (20150115) Y10T 428/249924 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321529 | Jones et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kevin D. Jones (Seaside, California); Vladimir N. Dobrokhodov (Seaside, California) |
| ABSTRACT | A hybrid buoy system capable of aerial operation, that in some embodiments includes a wireless communication technology to allow communication with other buoys and/or an external system. In some embodiments, a swarm of buoys may be capable of surface and/or air operation. These buoys may work together to perform collective tasks that individual buoys are not capable of. Buoy swarms may be programmed for cooperative and swarm behaviors for use in a broad spectrum of missions. At least some of the buoys may be configured for specialized sensing, increasing the collective sensing capabilities of the swarm. A mixed, swappable sensor suite may be used to accommodate an array of marine exploration applications, including both military and civilian applications. |
| FILED | Monday, April 07, 2014 |
| APPL NO | 14/246611 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/08 (20130101) B64C 39/02 (20130101) Original (OR) Class B64C 39/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321544 | Thompson et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Timothy Guy Thompson (Purcellville, Virginia); Matthew Phillip Ferringer (Round Hill, Virginia); Marc David DiPrinzio (South Riding, Virginia); Ronald Scott Clifton (Leesburg, Virginia) |
| ABSTRACT | Systems and methods are provided to determine launch parameters of satellites of a satellite constellation that provides optimized performance of the satellite constellation over the service lifetime of the satellite constellation. The launch parameters may be determined by considering perturbing accelerations of one or more of the satellites for the purposes of optimizing the launch parameters of the satellites of the satellite constellation. The systems and methods may include heuristic optimization and high-fidelity astrodynamic modeling methodologies. |
| FILED | Thursday, July 10, 2014 |
| APPL NO | 14/328026 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/002 (20130101) B64G 1/1085 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321700 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Scott L. Anderson (Salt Lake City, Utah); Brandon McMahon (Salt Lake City, Utah); Jesus Paulo L. Perez (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Scott L. Anderson (Salt Lake City, Utah); Brandon McMahon (Salt Lake City, Utah); Jesus Paulo L. Perez (Salt Lake City, Utah) |
| ABSTRACT | A method of producing nanoparticles can comprise milling a plurality of milling bodies sufficient to produce the nanoparticles from exterior surfaces of the plurality of milling bodies. In this manner, the milling bodies are simultaneously the milling media and the feedstock for production of nanoparticles such that additional solids are not present during milling. Nanoparticles can be readily formed and optional milling agent and capping agents can be provided to stabilize and/or customize the nanoparticles for a particular application. |
| FILED | Monday, August 06, 2012 |
| APPL NO | 13/567757 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 17/20 (20130101) B02C 17/186 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 9/04 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0066 (20130101) C06B 27/00 (20130101) Original (OR) Class Alloys C22C 9/00 (20130101) C22C 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321772 | Dar et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Mount Sinai School of Medicine (New York, New York) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Arvin C. Dar (San Francisco, California); Tirtha K. Das (New York, New York); Martin Sos (San Francisco, California); Trever G. Bivona (San Francisco, California); Kevan M. Shokat (San Francisco, California); Ross L. Cagan (New York, New York) |
| ABSTRACT | Presented herein are novel therapeutic compounds and methods of using the same for the treatment of cancers. |
| FILED | Tuesday, February 25, 2014 |
| APPL NO | 14/189742 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321803 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Xi Jiang (Cincinnati, Ohio); Ming Tan (Cincinnati, Ohio); Xufu Zhang (Guangdong, China PRC) |
| ABSTRACT | A composition for use in inhibiting the binding of a Norovirus to the histo-blood group antigen on the surface of epithelia is disclosed. The composition may contain a therapeutically effective amount of a binding-inhibiting compound and a carrier and/or excipient. The compounds may competitively bind a Norovirus that has the capability of binding with the histo-blood group antigens of secretor blood type, including A, B, AB, and O blood types. The compositions may be administered to a human prior to or after infection by a Norovirus, to prevent, ameliorate, or reduce the effects of an infection. |
| FILED | Wednesday, July 09, 2014 |
| APPL NO | 14/326894 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Steroids C07J 3/00 (20130101) C07J 7/002 (20130101) C07J 7/0005 (20130101) C07J 9/00 (20130101) C07J 9/005 (20130101) C07J 41/0005 (20130101) C07J 41/0016 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321920 | Fontana et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jake Fontana (Alexandria, Virginia); Jawad Naciri (Arlington, Virginia); Banahalli R. Ratna (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jake Fontana (Alexandria, Virginia); Jawad Naciri (Arlington, Virginia); Banahalli R. Ratna (Alexandria, Virginia) |
| ABSTRACT | A method of forming a monolayer film of nanoparticles includes forming a fluid mixture by combining nanoparticles dispersed in water with a water-miscible organic solvent and a molecular ligand comprising a head group with affinity for the nanoparticle, and introducing the fluid mixture to a substrate in the presence of an air/fluid interface, thereby causing a monolayer film of nanoparticles to form on the substrate. Such monolayers films can include metallic nanoparticles such as gold, and possess substantially uniform spacing over at least a one centimeter length scale. |
| FILED | Wednesday, February 20, 2013 |
| APPL NO | 13/771551 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0025 (20130101) B22F 1/0062 (20130101) B22F 7/04 (20130101) B22F 7/08 (20130101) B22F 2007/042 (20130101) B22F 2301/255 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 156/11 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321990 | Berns et al. |
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| FUNDED BY |
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| APPLICANT(S) | Michael W. Berns (Irvine, California); Thoru Pederson (Worchester, Massachusetts); Elliot Botvinick (Irvine, California); Linda Zhixia Shi (Vista, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Michael W. Berns (Irvine, California); Thoru Pederson (Worchester, Massachusetts); Elliot Botvinick (Irvine, California); Linda Zhixia Shi (Vista, California) |
| ABSTRACT | This invention relates to optomechanical systems and methods for altering, modifying or disrupting a target object. Such systems and methods are used for, for example, ablating the endogenous nucleus in a cell. |
| FILED | Friday, September 16, 2011 |
| APPL NO | 13/234986 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Original (OR) Class C12M 47/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) G01N 2015/149 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/12 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321994 | Betancourt |
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| FUNDED BY |
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| APPLICANT(S) | WibiWorks Therapeutics, Inc. (San Diego, California) |
| ASSIGNEE(S) | COMMENCE BIO, INC. (Sparks, Maryland) |
| INVENTOR(S) | Aline Betancourt (La Jolla, California) |
| ABSTRACT | Novel MSC stem-cell culture and therapy methods and culture medium compositions for the purpose of inducing, activating, or priming discrete uniform cell phenotypes to selectively promote or suppress inflammation and immunity, yielding polarized, primed, activated, or induced cells used in cell-based therapy. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 14/720603 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2500/92 (20130101) C12N 2501/14 (20130101) C12N 2501/24 (20130101) C12N 2501/25 (20130101) C12N 2501/58 (20130101) C12N 2501/2304 (20130101) C12N 2501/2313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322006 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); John Paul Guilinger (Ridgway, Colorado); Vikram Pattanayak (Cambridge, Massachusetts) |
| ABSTRACT | Engineered nucleases are promising tools for genome manipulation and determining off-target cleavage sites of these enzymes is of great interest. We developed an in vitro selection method that interrogates 1011 DNA sequences for their ability to be cleaved by nucleases. The method revealed hundreds of thousands of DNA sequences that can be cleaved in vitro by two ZFNs, CCR5-224 and VF2468, which target the endogenous human CCR5 and VEGF-A genes, respectively. Analysis of the identified sites in cultured human cells revealed CCR5-224-induced mutagenesis at nine off-target loci. Similarly, we observed 31 off-target sites cleaved by VF2468 in cultured human cells. Our findings establish an energy compensation model of ZFN specificity in which excess binding energy contributes to off-target ZFN cleavage and suggest strategies for the improvement of future nuclease design. It was also observed that TALENs can achieve cleavage specificity similar to or higher than that observed in ZFNs. |
| FILED | Monday, June 30, 2014 |
| APPL NO | 14/320271 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/6802 (20130101) C12Q 1/6802 (20130101) C12Q 1/6874 (20130101) C12Q 2521/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322007 | Arnold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Frances H. Arnold (La Canada, California); Indira Wu (Pasadena, California) |
| ASSIGNEE(S) | The California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Frances H. Arnold (La Canada, California); Indira Wu (Pasadena, California) |
| ABSTRACT | The disclosure provides variant Cel6a enzymes having increased thermostability, methods of making and using such polypeptides. |
| FILED | Friday, July 20, 2012 |
| APPL NO | 13/554736 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Original (OR) Class C12N 15/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/00 (20130101) C12P 7/10 (20130101) C12P 19/02 (20130101) C12P 19/14 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322023 | Delisa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Matthew Delisa (Ithaca, New York); Robert Conrado (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a synthetic nucleic acid scaffold comprising one or more subunits, each subunit comprising two or more different protein-binding sequences coupled together. The present invention further relates to systems and methods for assembling a synthetic biological pathway and producing a biological pathway product or a precursor product using the synthetic nucleic acid scaffold. |
| FILED | Tuesday, October 09, 2012 |
| APPL NO | 13/647898 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/80 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/00 (20130101) C12N 1/14 (20130101) C12N 1/20 (20130101) C12N 5/04 (20130101) C12N 5/06 (20130101) C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 15/52 (20130101) C12N 15/63 (20130101) C12N 15/115 (20130101) Original (OR) Class C12N 2310/13 (20130101) C12N 2310/51 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/18 (20130101) C12P 7/22 (20130101) C12P 7/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322285 | Devore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Matthew A. Devore (Manchester, Connecticut); Corneil S. Paauwe (Manchester, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Matthew A. Devore (Manchester, Connecticut); Corneil S. Paauwe (Manchester, Connecticut) |
| ABSTRACT | A turbine airfoil has a fillet connecting the nominal portion of the airfoil into an end wall. Cooling holes are formed over a greater circumferential extent in the fillet than they are through the nominal portion of the airfoil. |
| FILED | Wednesday, February 20, 2008 |
| APPL NO | 12/033918 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) F01D 9/041 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/81 (20130101) F05D 2240/121 (20130101) F05D 2240/303 (20130101) F05D 2260/202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322288 | Burd |
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| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Steven W. Burd (Cheshire, Connecticut) |
| ABSTRACT | A gas turbine engine has a pair of components having a high-pressure chamber on one side, and a low pressure chamber on an opposed side. A three-sided seal has one side in sealing contact with each of said components. A third side is associated with a third component. At least one non-metallic wear surface is positioned between one of the three sides of the seal and its respective component. |
| FILED | Thursday, November 29, 2012 |
| APPL NO | 13/688340 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/432 (20130101) Pistons; Cylinders; Sealings F16J 15/54 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/672 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322291 | DiBenedetto |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Hartford, Connecticut) |
| ASSIGNEE(S) | UNITED TECHNOLOGIES CORPORATION (Hartford, Connecticut) |
| INVENTOR(S) | Enzo DiBenedetto (Kensington, Connecticut) |
| ABSTRACT | Disclosed is a gas turbine engine including a plurality of inlet guide vanes. The gas turbine engine further includes an inlet case supporting each of the plurality of inlet guide vanes, and the inlet case is provided with at least one passageway in communication with a source of fluid. The at least one passageway is configured to communicate the fluid to each of the plurality of inlet guide vanes. |
| FILED | Friday, December 14, 2012 |
| APPL NO | 13/714788 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/065 (20130101) F01D 25/02 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/047 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/31 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49321 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322618 | Tuttle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Cara Tuttle (West Roxbury, Massachusetts); Magdalena Mulherin (Marlborough, Massachusetts); Annette LaFleur (Natick, Massachusetts); Kristine Isherwood (Boston, Massachusetts); Katherine Mitchell (Natick, Massachusetts) |
| ABSTRACT | A blast debris protective harness includes a front shell portion and a rear shell portion joined together. Each of the front and rear shell portions has an inside shell member and an outside shell member. A cavity is defined between the inside shell member and the outside shell member. A ballistic insert is configured to be retained within the cavity. The harness is an outer garment. |
| FILED | Tuesday, November 27, 2012 |
| APPL NO | 13/685747 |
| ART UNIT | 3765 — AI & Simulation/Modeling |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 1/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322648 | Karvounis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
| ASSIGNEE(S) | TRX Systems, Inc. (Greenbelt, Maryland) |
| INVENTOR(S) | John Karvounis (Bowie, Maryland); Jared Napora (Severn, Maryland); Dan Hakim (Silver Spring, Maryland); Carole Teolis (Glenn Dale, Maryland); John Riley Miller (Hanover, Maryland); Benjamin E. Funk (Ellicott, Maryland) |
| ABSTRACT | A method for determining an environmental pressure change affecting a pressure sensor within a portable device to determine an elevation of the portable device is disclosed. The method involves sampling pressure data from at least one stationary pressure sensor in an area surrounding a location of the device, wherein the stationary pressure sensor in not within the portable device. The sampled pressure data is then interpolated to a time interval and a difference is computed between the interpolated pressure data over each time interval to determine a differential pressure. The location of the stationary pressure sensor is determined and the differential pressure is added to a pressure map affecting data near the location. The environmental pressure change is then computed over any interval at the location and subtracted from a pressure measurement of the pressure sensor before computing an elevation of the portable device. |
| FILED | Friday, May 15, 2015 |
| APPL NO | 14/714209 |
| ART UNIT | 2865 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 5/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322712 | Neshat et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mohammad Neshat (Baltimore, Maryland); N. Peter Armitage (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Mohammad Neshat (Baltimore, Maryland); N. Peter Armitage (Baltimore, Maryland) |
| ABSTRACT | A terahertz time-domain spectroscopic ellipsometry system includes a sample stage, a terahertz emitter configured to provide pulses of terahertz radiation with preselected polarization components to illuminate a sample on the sample stage along an incident direction, and a coherent terahertz detection system arranged to coherently detect pulses of terahertz radiation from the terahertz emitter along an emerging direction after at least one of reflecting from or passing through the sample. The sample stage is rotatable to vary a relative angle between the incident direction and the emerging direction, and the coherent terahertz detection system substantially maintains alignment for amplitude and polarization detection as the relative angle is varied. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/841316 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/211 (20130101) G01N 21/3586 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322768 | Carrieri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Development and Engineering Command (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Arthur H. Carrieri (Abingdon, Maryland); Tudor N. Buican (Albuquerque, New Mexico); Erik S. Roese (Baltimore, Maryland); James Sutter (Tucson, Arizona); Alan C. Samuels (Havre de Grace, Maryland) |
| ABSTRACT | A pseudo-active chemical imaging sensor including irradiative transient heating, temperature nonequilibrium thermal luminescence spectroscopy, differential hyperspectral imaging, and artificial neural network technologies integrated together. The sensor may be applied to the terrestrial chemical contamination problem, where the interstitial contaminant compounds of detection interest (analytes) comprise liquid chemical warfare agents, their various derivative condensed phase compounds, and other material of a life-threatening nature. The sensor measures and processes a dynamic pattern of absorptive-emissive middle infrared molecular signature spectra of subject analytes to perform its chemical imaging and standoff detection functions successfully. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/796166 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) G01J 3/447 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) Original (OR) Class G01N 21/27 (20130101) G01N 21/71 (20130101) G01N 21/71 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322804 | Whitesides et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George M. Whitesides (Cambridge, Massachusetts); Audrey Ellerbee (Stanton, California); Simon Tricard (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Whitesides (Cambridge, Massachusetts); Audrey Ellerbee (Stanton, California); Simon Tricard (Cambridge, Massachusetts) |
| ABSTRACT | The ability to levitate and detect height and orientation of diamagnetic objects suspended in paramagnetic solutions using an inhomogeneous magnetic field is described. By comparing the measured height and orientation of a sample material with the measured height and orientation of a reference material, quality control of objects can be carried out. The major advantages of this quality control technique are: i) it is a simple apparatus that does not require electric power (a set of permanent magnets and gravity are sufficient for the diamagnetic separation and collection system to work); ii) it is compatible with simple optical detection; iii) it is a cost-effective and simple method that can carry out quality control between sample and reference materials rapidly. |
| FILED | Tuesday, November 29, 2011 |
| APPL NO | 13/989725 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/1269 (20130101) G01R 33/1276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322847 | Hamilton |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brett J Hamilton (Heltonville, Indiana) |
| ABSTRACT | A test system including an embodiment having a sensor array adapted to test one or more devices under test in learning modes as well as evaluation modes. An exemplary test system can collect a variety of test data as a part of a machine learning system associated with known-good samples. Data collected by the machine learning system can be used to calculate probabilities that devices under test in an evaluation mode meet a condition of interest based on multiple testing and sensor modalities. Learning phases or modes can be switched on before, during, or after evaluation mode sequencing to improve or adjust machine learning system capabilities to determine probabilities associated with different types of conditions of interest. Multiple permutations of probabilities can collectively be used to determine an overall probability of a condition of interest which has a variety of attributes. |
| FILED | Tuesday, June 24, 2014 |
| APPL NO | 14/313360 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/07 (20130101) Original (OR) Class G01R 31/2834 (20130101) Electric Digital Data Processing G06F 11/2263 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322872 | Hill |
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| FUNDED BY |
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| APPLICANT(S) | David T. Hill (Bedford, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David T. Hill (Bedford, Indiana) |
| ABSTRACT | A computer implemented system for testing electronic equipment where test inputs, test outputs, test applied environmental conditions, and test processes are recorded and correlated. |
| FILED | Tuesday, May 31, 2011 |
| APPL NO | 13/149855 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2849 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323051 | Weiller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Bruce H. Weiller (Santa Monica, California); Jesse D. Fowler (El Segundo, California); Randy M. Villahermosa (Pasadena, California) |
| ABSTRACT | Embodiments of the present invention provide systems and methods for inhibiting contamination enhanced laser induced damage (CELID) based on fluorinated self-assembled monolayers (F-SAMs) disposed on optics. For example, a coating for inhibiting CELID to an optic disposed in a sealed gas environment or vacuum may include an F-SAM that includes a fluorinated hydrocarbon tail group covalently bound to the optic by a head group. The coating may be formed by heating the optic and a liquid-phase precursor of the F-SAM to generate a gas-phase precursor, and exposing the heated optic to the gas-phase precursor for a period of time sufficient for the gas-phase precursor to coalesce at and covalently bond to the optic and form the F-SAM. The optic may include silica, and the F-SAM may include a siloxane group covalently bound to the silica. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/802042 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0006 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/31663 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323063 | Soskind et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yakov Soskind (Plainsboro, New Jersey); Richard Gifford (Toms River, New Jersey); Joseph Aletta (Jackson, New Jersey) |
| ASSIGNEE(S) | DHPC TECHNOLOGIES, INC. (Woodbridge, New Jersey) |
| INVENTOR(S) | Yakov Soskind (Plainsboro, New Jersey); Richard Gifford (Toms River, New Jersey); Joseph Aletta (Jackson, New Jersey) |
| ABSTRACT | A diode laser beam combining apparatus for producing a high combined beam power density in the far field at reduced levels of power consumption and heat dissipation includes an array of semiconductor laser emitters arranged in a collinear manner with respect to each other and having an emitter pitch between about 0.7 mm and 2.5 mm. The apparatus also includes a cylindrical lens for collimating emitter beams generated by the array of laser emitters in a direction perpendicular to a junction plane of the laser emitters. The apparatus further includes a micro-optic array and a long focal length cylindrical lens. The micro-optic array is configured to perform a rotational transformation of the collimated emitter beams. The micro-optic array has a lateral spacing in a direction parallel to the junction plane of the laser emitters that matches the emitter pitch. The long focal length cylindrical lens collimates emitter beams in the direction perpendicular to the junction plane after passing through the micro-optic array. |
| FILED | Friday, April 29, 2011 |
| APPL NO | 13/097156 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 19/0014 (20130101) G02B 19/0057 (20130101) G02B 19/0061 (20130101) G02B 27/12 (20130101) Original (OR) Class G02B 27/0961 (20130101) G02B 27/0966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323217 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shih-Yuan Wang (Palo Alto, California); Alexandre M. Bratkovski (Mountain View, California); R. Stanley Williams (Portola Valley, California); Jingjing Li (Sunnyvale, California); Wei Wu (Palo Alto, California); Philip J. Kuekes (Menlo Park, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea) |
| INVENTOR(S) | Shih-Yuan Wang (Palo Alto, California); Alexandre M. Bratkovski (Mountain View, California); R. Stanley Williams (Portola Valley, California); Jingjing Li (Sunnyvale, California); Wei Wu (Palo Alto, California); Philip J. Kuekes (Menlo Park, California) |
| ABSTRACT | A negative index material (or metamaterial) crossbar includes a first layer of approximately parallel nanowires and a second layer of approximately parallel nanowires that overlay the nanowires in the first layer. The nanowires in the first layer are approximately perpendicular in orientation to the nanowires in the second layer. Each nanowire of the first layer and each nanowire of the second layer has substantially regularly spaced fingers. The crossbar further includes resonant elements at nanowire intersections between the respective layers. Each resonant element includes two fingers of a nanowire in the first layer and two fingers of a nanowire in the second layer. |
| FILED | Monday, December 29, 2008 |
| APPL NO | 13/142484 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/007 (20130101) Holographic Processes or Apparatus G03H 1/02 (20130101) Original (OR) Class G03H 1/2249 (20130101) G03H 1/2294 (20130101) G03H 2001/0224 (20130101) G03H 2210/30 (20130101) G03H 2225/22 (20130101) G03H 2225/32 (20130101) G03H 2225/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323284 | Foster et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark Foster (Sparks Glencoe, Maryland); Alexander Gaeta (Ithaca, New York); David Geraghty (Menlo Park, California); Michal Lipson (Ithaca, New York); Reza Salem (Columbia, Maryland); Amy Foster (Sparks Glencoe, Maryland) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Mark Foster (Sparks Glencoe, Maryland); Alexander Gaeta (Ithaca, New York); David Geraghty (Menlo Park, California); Michal Lipson (Ithaca, New York); Reza Salem (Columbia, Maryland); Amy Foster (Sparks Glencoe, Maryland) |
| ABSTRACT | There is set forth in one embodiment an apparatus and method for imparting a phase shift to an input waveform for output of a converted waveform. In one embodiment, a phase shift can be provided by four wave mixing of an input waveform and a pump pulse. In one embodiment, there is set forth an apparatus and method for generating a high resolution time domain representation of an input waveform comprising: dispersing the input waveform to generate a dispersed input waveform; subjecting the dispersed input waveform to four wave mixing by combining the dispersed input waveform with a dispersed pump pulse to generate a converted waveform; and presenting the converted waveform to a detector unit. In one embodiment a detector unit can include a spectrometer (spectrum analyzer) for recording of the converted waveform and output of a record representing the input waveform. |
| FILED | Wednesday, October 14, 2009 |
| APPL NO | 13/124305 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/00 (20130101) G01J 11/00 (20130101) G01J 2009/0226 (20130101) Optical Elements, Systems, or Apparatus G02B 27/46 (20130101) Optical Computing Devices; G06E 3/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323332 | Braun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IMMERSION CORPORATION (San Jose, California) |
| ASSIGNEE(S) | Immersion Corporation (San Jose, California) |
| INVENTOR(S) | Adam C. Braun (Portland, Oregon); Jonathan L. Beamer (Lyndhurst, Ohio); Dean C. Chang (Gaithersburg, Maryland) |
| ABSTRACT | A force feedback system provides components for use in a force feedback system including a host computer and a force feedback interface device. An architecture for a host computer allows multi-tasking application programs to interface with the force feedback device without conflicts. One embodiment of a force feedback device provides both relative position reporting and absolute position reporting to allow great flexibility. A different device embodiment provides relative position reporting device allowing maximum compatibility with existing software. Information such as ballistic parameters and screen size sent from the host to the force feedback device allow accurate mouse positions and graphical object positions to be determined in the force feedback environment. Force feedback effects and structures are further described, such as events and enclosures. |
| FILED | Monday, January 05, 2015 |
| APPL NO | 14/589355 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) Original (OR) Class G06F 3/0481 (20130101) G06F 3/03543 (20130101) G06F 2203/014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323397 | Boser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bernhard E. Boser (Berkeley, California); Richard J. Przybyla (Berkeley, California); Andre Guedes (San Francisco, California); David A. Horsley (Albany, California); Stefon E. Shelton (Oakland, California) |
| ABSTRACT | An apparatus for determining location of a moveable object in relation to an input device includes an array of one or more piezoelectric micromachined ultrasonic transducer (pMUT) elements and a processor. The array is formed from a common substrate. The one or more pMUT elements include one or more transmitters and one or more receivers. The processor configured to determine a location of a moveable object in relation to an input device using sound waves that are emitted from the one or more transmitters, reflected from the moveable object, and received by the one or more receivers. |
| FILED | Tuesday, March 11, 2014 |
| APPL NO | 14/204917 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/043 (20130101) Original (OR) Class G06F 2203/04101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323418 | DiVita et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph C. DiVita (Carlsbad, California); Robert L. Morris (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph C. DiVita (Carlsbad, California); Robert L. Morris (San Diego, California) |
| ABSTRACT | A method for analysis of a prototype graphical user interface (GUI) comprising the following steps: receiving, with a processor, a computer code representative of the prototype GUI, wherein the prototype GUI comprises GUI elements having known identities and known behavioral attributes; transforming the computer code into a description of visible sub-elements of the prototype GUI elements, wherein each sub-element has visual properties that would be visible to a user of the prototype GUI; grouping particular visible sub-elements into a perceived GUI element based only on the sub-elements' visual properties according to a grouping algorithm without regard to the known identity(ies) of the prototype GUI element(s) to which the particular sub-elements belong; and storing, in a non-transitory first memory store, the perceived GUI element. |
| FILED | Friday, November 08, 2013 |
| APPL NO | 14/075374 |
| ART UNIT | 2179 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0481 (20130101) Original (OR) Class G06F 8/36 (20130101) G06F 8/38 (20130101) G06F 11/3608 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323795 | Blain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Cheryl Ann Blain (Slidell, Louisiana); Robert S. Linzell (Carriere, Mississippi); Brett D. Estrade (SugarLand, Texas) |
| ABSTRACT | A system and method for converting structured data to unstructured or structured data, the system and method receiving processing options in a flexible format and a reader selection, executing the reader selection to read data, computing a date time group to iterate through observed and/or modeled data, bilinearly interpolating the structured data to create an unstructured or structured finite element mesh, linearly interpolating data in time if necessary, and storing the populated grid on a computer-readable medium in a format compatible with a target numerical model. |
| FILED | Tuesday, February 18, 2014 |
| APPL NO | 14/182561 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30312 (20130101) Original (OR) Class G06F 17/30569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324403 | Khalili Amiri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Pedram Khalili Amiri (Los Angeles, California); Kang L. Wang (Santa Monica, California); Kosmas Galatsis (Torrance, California) |
| ABSTRACT | Voltage controlled magnetic tunnel junctions and memory devices are described which provide efficient high speed switching of non-volatile magnetic devices at high cell densities. Implementations are described which provide a wide range of voltage control alternatives with in-plane and perpendicular magnetization, bidirectionally switched magnetization, and control of domain wall dynamics. |
| FILED | Thursday, July 30, 2015 |
| APPL NO | 14/813421 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/161 (20130101) Original (OR) Class G11C 11/1673 (20130101) G11C 11/1675 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3254 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 43/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324421 | Perner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Frederick Perner (Santa Barbara, California); Wei Yi (Mountain View, California); Matthew D. Pickett (San Francisco, California) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| INVENTOR(S) | Frederick Perner (Santa Barbara, California); Wei Yi (Mountain View, California); Matthew D. Pickett (San Francisco, California) |
| ABSTRACT | A method of switching a memristive device applies a current ramp of a selected polarity to the memristive device. The resistance of the device during the current ramp is monitored. When the resistance of the memristive device reaches the target value, the current ramp is removed. |
| FILED | Monday, January 31, 2011 |
| APPL NO | 13/884107 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 13/0002 (20130101) Original (OR) Class G11C 13/0007 (20130101) G11C 13/0064 (20130101) G11C 13/0069 (20130101) G11C 2013/0066 (20130101) G11C 2013/0073 (20130101) G11C 2013/0078 (20130101) G11C 2211/5624 (20130101) G11C 2211/5645 (20130101) G11C 2213/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324422 | Pop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eric Pop (Champaign, Illinois); Feng Xiong (Urbana, Illinois); Albert D. Liao (Champaign, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Eric Pop (Champaign, Illinois); Feng Xiong (Urbana, Illinois); Albert D. Liao (Champaign, Illinois) |
| ABSTRACT | A system that incorporates teachings of the subject disclosure may include, for example, a device including a nanoelectrode having a gap, and a resistive change material located in the gap, wherein an application of a voltage potential across first and second terminals of the nanoelectrode causes the resistive change material to modify at least one non-volatile memory state of the resistive change material. Additional embodiments are disclosed. |
| FILED | Wednesday, April 18, 2012 |
| APPL NO | 13/449891 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Static Stores G11C 13/0004 (20130101) Original (OR) Class G11C 13/025 (20130101) G11C 2213/35 (20130101) G11C 2213/53 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/06 (20130101) H01L 45/065 (20130101) H01L 45/144 (20130101) H01L 45/1226 (20130101) H01L 45/1253 (20130101) H01L 45/1625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324473 | Lavrentovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oleg D. Lavrentovich (Kent, Ohio); Heung-Shik Park (Kent, Ohio) |
| ASSIGNEE(S) | KENT STATE UNIVERSITY (Kent, Ohio) |
| INVENTOR(S) | Oleg D. Lavrentovich (Kent, Ohio); Heung-Shik Park (Kent, Ohio) |
| ABSTRACT | A nanoparticle composition, a device including the nanoparticle composition, and a method thereof are provided. The composition comprises nanoparticles such as Gold nanorods (NR) and electrically charged self-assembled molecular aggregates such as disodium chromoglycate (DSCG) in a common solvent such as water. The nanoparticles are assembled as, for example, side-by-side and end-to-end assemblies of nanorods, through a non-covalent interaction such as anisotropic electrostatic interaction with the electrically charged self-assembled molecular aggregates. The invention can be used in a cloaking device, a biological sensing device, a drug delivery, a meta material, a negative index material, an enhanced imaging device, and a device for solar energy conversion, and exhibits many merits such as simpler process without the need of a covalent bonding between the nanoparticles, different manners of nanoparticles assembling with same linker, higher thermal stability, cost effectiveness, and capability of gradual controlling of the degree of NR assembly, among others. |
| FILED | Tuesday, August 25, 2009 |
| APPL NO | 12/547062 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0022 (20130101) B22F 1/0025 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324560 | Shatalov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| ASSIGNEE(S) | Sensor Electronic Technology, Inc. (Columbia, South Carolina) |
| INVENTOR(S) | Maxim S. Shatalov (Columbia, South Carolina); Rakesh Jain (Columbia, South Carolina); Jinwei Yang (Columbia, South Carolina); Michael Shur (Latham, New York); Remigijus Gaska (Columbia, South Carolina) |
| ABSTRACT | A patterned surface for improving the growth of semiconductor layers, such as group III nitride-based semiconductor layers, is provided. The patterned surface can include a set of substantially flat top surfaces and a plurality of openings. Each substantially flat top surface can have a root mean square roughness less than approximately 0.5 nanometers, and the openings can have a characteristic size between approximately 0.1 micron and five microns. One or more of the substantially flat top surfaces can be patterned based on target radiation. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 14/660125 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0237 (20130101) Original (OR) Class H01L 21/0242 (20130101) H01L 21/0243 (20130101) H01L 21/0254 (20130101) H01L 21/0265 (20130101) H01L 21/02458 (20130101) H01L 21/02639 (20130101) H01L 33/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324579 | Presser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Nathan Presser (West Hollywood, California); David P. Taylor (Hawthorne, California) |
| ABSTRACT | Embodiments of the present invention provide metal structures for transporting or gettering materials disposed on or within a semiconductor substrate. A structure for transporting a material disposed on or within a semiconductor substrate may include a metal structure disposed within the semiconductor substrate and at a spaced distance from the material. The metal structure is configured to transport the material through the semiconductor substrate and to concentrate the material at the metal structure. The material may include a contaminant disposed within the semiconductor substrate, e.g., that originates from electronic circuitry on the substrate. |
| FILED | Thursday, March 14, 2013 |
| APPL NO | 13/830856 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/74 (20130101) H01L 21/3221 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324893 | Kats et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael Kats (Rockaway, New Jersey); Emrah Kulunk (Albuquerque, New Mexico); James Sherman (Hillsborough, New Jersey); Daniel Aiken (Cedar Crest, New Mexico) |
| ABSTRACT | A portable solar power system and a method for deploying the portable solar power system are disclosed. The portable solar power system may include a foldable plate including a non-foldable portion and at least one foldable portion with respective to the non-foldable portion, both of which have respective surfaces on which a solar cell array is mounted; a rotating mechanism for rotating the foldable plate at least in a generally horizontal plane; and a mast for supporting at least a part of the rotating mechanism and the foldable plate. |
| FILED | Tuesday, December 10, 2013 |
| APPL NO | 14/102053 |
| ART UNIT | 1758 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/045 (20130101) H01L 31/0422 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324938 | Kelber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QUANTUM DEVICES, LLC (Potomac, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF NORTH TEXAS (Denton, Texas) |
| INVENTOR(S) | Jeffry Kelber (Denton, Texas); Peter Dowben (Lincoln, Nebraska) |
| ABSTRACT | Boron carbide polymers prepared from orthocarborane icosahedra cross-linked with a moiety A wherein A is selected from the group consisting of benzene, pyridine. 1,4-diaminobenzene and mixtures thereof give positive magnetoresistance effects of 30%-80% at room temperature. The novel polymers may be doped with transitional metals to improve electronic and spin performance. These polymers may be deposited by any of a variety of techniques, and may be used in a wide variety of devices including magnetic tunnel junctions, spin-memristors and non-local spin valves. |
| FILED | Friday, December 06, 2013 |
| APPL NO | 14/098759 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/08 (20130101) H01L 43/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324960 | Dowben et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Peter Dowben (Lincoln, Nebraska); Jeffry Kelber (Denton, Texas) |
| ASSIGNEE(S) | QUANTUM DEVICES, LLC (Rockville, Maryland) |
| INVENTOR(S) | Peter Dowben (Lincoln, Nebraska); Jeffry Kelber (Denton, Texas) |
| ABSTRACT | Novel semiconducting polymers have been formed via the electron-induced cross-linking of orthocarborane B10C2H2 and 1,4-diaminobenzene. The films were formed by co-condensation of the molecular precursors and 200 eV electron-induced cross-linking under ultra-high vacuum (UHV) conditions. Ultraviolet photoemission spectra show that the compound films display a shift of the valence band maximum from ˜4.3 eV below the Fermi level for pure boron carbide to −1.7 eV below the Fermi level when diaminobenzene is added. The surface photovoltage effect decreases with decreasing B/N atomic ratio. A neutron detector comprises the polymer as the p-type semiconductor to be paired with an n-type semiconductor. |
| FILED | Monday, June 04, 2012 |
| APPL NO | 14/115104 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0043 (20130101) H01L 51/4213 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325073 | Waters |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey M. Waters (Solsberry, Indiana) |
| ABSTRACT | Systems and methods for assembling different multi-element items with different specifications using a reconfigurable apparatus are provided. One embodiment includes a base plate, a back plate coupled to the base plate in a predetermined angle relationship. The exemplary back plate comprises a plurality of alignment pins adapted to engage with alignment locations of multiple element assembly items. The exemplary base plate and alignment mounting structures couple to end cap parts disposed on opposing ends of the multiple element assembly items holding the items together. A clamping mechanism maintains/releases pressure on the multiple element assembly items against the back plate. The back plate holds alignment pins in a first back plate location in a first orientation for one type of multiple element assembly items and hold the alignment pins in a second location when the back plate is in a second orientation for a different type of multiple element assembly items. |
| FILED | Friday, April 11, 2014 |
| APPL NO | 14/250534 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 5/12 (20130101) B25B 11/02 (20130101) Antennas, i.e Radio Aerials H01Q 1/1207 (20130101) H01Q 13/0283 (20130101) Original (OR) Class H01Q 21/064 (20130101) H01Q 21/0087 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4902 (20150115) Y10T 29/49016 (20150115) Y10T 29/49899 (20150115) Y10T 29/53961 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325140 | Purnawirman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purnawirman Purnawirman (Watertown, Massachusetts); Michael R. Watts (Hingham, Massachusetts); Ehsan Shah Hosseini (Medford, Massachusetts); Jonathan D. B. Bradley (Boston, Massachusetts); Jie Sun (Cambridge, Massachusetts); Matteo Cherchi (Espoo, Finland) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Purnawirman Purnawirman (Watertown, Massachusetts); Michael R. Watts (Hingham, Massachusetts); Ehsan Shah Hosseini (Medford, Massachusetts); Jonathan D. B. Bradley (Boston, Massachusetts); Jie Sun (Cambridge, Massachusetts); Matteo Cherchi (Espoo, Finland) |
| ABSTRACT | Examples of the present invention include integrated erbium-doped waveguide lasers designed for silicon photonic systems. In some examples, these lasers include laser cavities defined by distributed Bragg reflectors (DBRs) formed in silicon nitride-based waveguides. These DBRs may include grating features defined by wafer-scale immersion lithography, with an upper layer of erbium-doped aluminum oxide deposited as the final step in the fabrication process. The resulting inverted ridge-waveguide yields high optical intensity overlap with the active medium for both the 980 nm pump (89%) and 1.5 μm laser (87%) wavelengths with a pump-laser intensity overlap of over 93%. The output powers can be 5 mW or higher and show lasing at widely-spaced wavelengths within both the C- and L-bands of the erbium gain spectrum (1536, 1561 and 1596 nm). |
| FILED | Friday, March 07, 2014 |
| APPL NO | 14/200427 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/17 (20130101) H01S 3/083 (20130101) H01S 3/0632 (20130101) Original (OR) Class H01S 3/0635 (20130101) H01S 3/1053 (20130101) H01S 3/1608 (20130101) H01S 3/2308 (20130101) H01S 3/08059 (20130101) H01S 3/094096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325176 | Siri |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kasemsan Siri (Torrance, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Kasemsan Siri (Torrance, California) |
| ABSTRACT | Embodiments of the present invention provide an apparatus for optimum power tracking for distributed power sources. The apparatus includes a plurality of distributed-input parallel-output converters. Each converter is operably connected to a corresponding power source to form a power-processing channel. The apparatus also includes a controller operably connected to the plurality of converters, and is configured to provide uniform input voltages across each power source while tracking an optimum power point. The controller provides tolerance for multiple faults up to N−1 power source failures for the apparatus comprising an N-channel converter power system with N distributed power sources. |
| FILED | Wednesday, May 02, 2012 |
| APPL NO | 13/462112 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/385 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/58 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/707 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325331 | Ainspan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Herschel A. Ainspan (New Hempstead, New York); Mark Ferriss (Tarrytown, New York); Daniel J. Friedman (Sleepy Hollow, New York); Alexander V. Rylyakov (Mount Kisco, New York); Bodhisatwa Sadhu (White Plains, New York); Alberto Valdes Garcia (Hartsdale, New York) |
| ABSTRACT | Methods and systems for phase correction include determining a phase error direction and generating a prediction for the phase error based on a sigma-delta error. It is determined whether the prediction agrees with the determined phase error direction. If the prediction does not agree, a phase correction is adjusted in accordance with the predicted phase error. |
| FILED | Tuesday, November 03, 2015 |
| APPL NO | 14/931234 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/085 (20130101) Original (OR) Class H03L 7/0992 (20130101) H03L 7/1974 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325332 | Ainspan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Herschel A. Ainspan (New Hempstead, New York); Mark A. Ferriss (Tarrytown, New York); Daniel J. Friedman (Sleepy Hollow, New York); Alexander V. Rylyakov (Mount Kisco, New York); Bodhisatwa Sadhu (White Plains, New York); Alberto Valdes-Garcia (Chappaqua, New York) |
| ABSTRACT | An apparatus comprises a digitally controlled circuit having a variable capacitance and a controller configured to adjust a magnitude of the variable capacitance of the digitally controlled circuit. The digitally controlled circuit comprises a plurality of gain elements, the plurality of gain elements comprising one or more positive voltage-to-frequency gain elements and one or more negative voltage-to-frequency gain elements. The controller is configured to adjust the magnitude of the capacitance by adjusting the gain provided by respective ones of the gain elements in an alternating sequence of the positive voltage-to-frequency gain elements and the negative voltage-to-frequency gain elements. |
| FILED | Monday, February 09, 2015 |
| APPL NO | 14/617507 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 1/00 (20130101) H03B 5/1212 (20130101) H03B 5/1265 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 11/04 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/093 (20130101) H03L 7/0992 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325436 | Pratt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Thomas G. Pratt (Covington, Georgia); Brett T. Walkenhorst (Douglasville, Georgia) |
| ABSTRACT | The present invention describes methods and apparatus for adaptive polarization transmission. An exemplary embodiment of the present invention provides an adaptive polarization transmission method. The method includes the step of analyzing at a transmitter device a first set of polarization state information relating to a first wireless signal path. Furthermore, the method includes the step of adapting a transmission signal to be distributed by the transmitter device based on at least the first set of polarization state information. In addition to adaptive polarization transmission methods, the present invention provides various adaptive polarization transmission systems. In an exemplary embodiment, an adaptive polarization transmission system includes a transmitter device. The transmitter device includes an analyzing unit for processing a first set of polarization state information relating to a first wireless signal path. Furthermore, the transmitter device includes an adapting unit for adapting a transmission signal to be distributed by the transmitter device based on at least the first set polarization state information. |
| FILED | Tuesday, December 10, 2013 |
| APPL NO | 14/101821 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission H04B 7/10 (20130101) H04B 7/0413 (20130101) H04B 17/003 (20130101) Original (OR) Class H04B 17/101 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325493 | Sethumadhavan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lakshminarasimhan Sethumadhavan (New York, New York); Adam Waksman (Pleasantville, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Lakshminarasimhan Sethumadhavan (New York, New York); Adam Waksman (Pleasantville, New York) |
| ABSTRACT | Methods for preventing activation of hardware backdoors installed in a digital circuit, the digital circuit comprising one or more hardware units to be protected. A timer is repeatedly initiated for a period less than a validation epoch, and the hardware units are reset upon expiration of the timer to prevent activation of a time-based backdoor. Data being sent to the hardware unit is encrypted in an encryption element to render it unrecognizable to a single-shot cheat code hardware backdoor present in the hardware unit. The instructions being sent to the hardware unit are reordered randomly or pseudo-randomly, with determined sequential restraints, using an reordering element, to render an activation instruction sequence embedded in the instructions unrecognizable to a sequence cheat code hardware backdoor present in the hardware unit. |
| FILED | Friday, March 27, 2015 |
| APPL NO | 14/671905 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/76 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/002 (20130101) Original (OR) Class H04L 9/008 (20130101) H04L 2209/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325671 | Rohloff |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| INVENTOR(S) | Kurt Ryan Rohloff (South Hadley, Massachusetts) |
| ABSTRACT | A method for data privacy in a distributed communication system, in which a plurality of client terminals are arranged in a ring configuration merges encrypted streaming data using circular encryption key switching and without sharing any private keys in a distributed communication system. The merged data is then sent to client terminals to be further process by respective client terminals. |
| FILED | Wednesday, February 19, 2014 |
| APPL NO | 14/184541 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/06 (20130101) H04L 63/061 (20130101) H04L 63/0428 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325914 | Marandos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Peter Marandos (Bloomington, Indiana); Grady Patterson (Greer, South Carolina); Kenneth Leeson (Edgewood, New Mexico) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Peter Marandos (Bloomington, Indiana); Grady Patterson (Greer, South Carolina); Kenneth Leeson (Edgewood, New Mexico) |
| ABSTRACT | An apparatus and method for characterization of a directed beam of electromagnetic radiation is provided. An exemplary embodiment of the invention can include an apparatus and measuring technique method which uses a model for blackbody radiation that includes consideration all the degrees of freedom due to translation, vibration, and rotation of molecules or atoms that make up the absorber and a heat transfer term which averages the behavior of all the atoms of the material as a function of temperature. This apparatus and method provides an advantage of increased accuracy, substantial reductions of time required for processing, simplification of measuring processes, and reduction required equipment. |
| FILED | Thursday, August 15, 2013 |
| APPL NO | 13/967823 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0003 (20130101) G01J 5/58 (20130101) G01J 2005/0077 (20130101) G01J 2005/0085 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09326383 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California) |
| ASSIGNEE(S) | Teledyne Scientific and Imaging, LLC. (Thousand Oaks, California) |
| INVENTOR(S) | Steve Qingjun Cai (Newbury Park, California); Chung-Lung Chen (Thousand Oaks, California); Chialun Tsai (Thousand Oaks, California) |
| ABSTRACT | A system and method is disclosed for fabricating a heat spreader system, including providing a plurality of bottom microporous wicks recessed in a bottom substrate, bonding a center substrate to the bottom substrate, and bonding a top substrate having a top chamber portion to the center substrate to establish a first vapor chamber with said plurality of bottom microporous wicks. |
| FILED | Friday, June 07, 2013 |
| APPL NO | 13/913114 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) F28D 15/0266 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4882 (20130101) H01L 23/427 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/22 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49352 (20150115) Y10T 29/49353 (20150115) Y10T 156/10 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09326384 | Deshpande |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America Navy as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nishkamraj Deshpande (Novi, Michigan) |
| ABSTRACT | The present invention relates application of conformal coatings made up of nano-fiber, nano-particle, and/or nano-capsule materials to be applied on electrical component parts in general and printed circuit boards (PCB) in particular. A conformal coating material, such as Parlyne, can be combined with nano-materials to produce desired results. Benefits of this invention include enhancement of conventional conformal coatings performance in terms of properties such as mechanical, electrical, magnetic and in particular to prevent or obstruct the growth of tin whiskers or any other manufacturing defect that can develop on the surface of a PCB. |
| FILED | Thursday, March 27, 2014 |
| APPL NO | 14/227391 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/28 (20130101) Original (OR) Class H05K 3/284 (20130101) H05K 2201/0251 (20130101) H05K 2201/0257 (20130101) H05K 2201/0769 (20130101) H05K 2201/09872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 09320428 | Taylor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Russell H. Taylor (Severna Park, Maryland); Seth D. Billings (Pellston, Maryland); Peter L. Gehlbach (Hunt Valley, Maryland); Gregory D. Hager (Baltimore, Maryland); James T. Handa (Baltimore, Maryland); Jin Ung Kang (Ellicott City, Maryland); Balazs Vagvolgyi (Baltimore, Maryland); Raphael Sznitman (Baltimore, Maryland); Zachary Pezzementi (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Russell H. Taylor (Severna Park, Maryland); Seth D. Billings (Pellston, Maryland); Peter L. Gehlbach (Hunt Valley, Maryland); Gregory D. Hager (Baltimore, Maryland); James T. Handa (Baltimore, Maryland); Jin Ung Kang (Ellicott City, Maryland); Balazs Vagvolgyi (Baltimore, Maryland); Raphael Sznitman (Baltimore, Maryland); Zachary Pezzementi (Baltimore, Maryland) |
| ABSTRACT | An observation system for viewing light-sensitive tissue includes an illumination system configured to illuminate the light-sensitive tissue, an imaging system configured to image at least a portion of the light-sensitive tissue upon being illuminated by the illumination system, and an image display system in communication with the imaging system to display an image of the portion of the light-sensitive tissue. The illumination system is configured to illuminate the light-sensitive tissue with a reduced amount of light within a preselected wavelength range compared to multispectral illumination light, and the image of the portion of the light-sensitive tissue is compensated for the reduced amount of light within the preselected frequency range to approximate an image of the light-sensitive tissue under the multispectral illumination. |
| FILED | Thursday, August 05, 2010 |
| APPL NO | 13/387950 |
| ART UNIT | 3737 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/13 (20130101) Original (OR) Class A61B 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320452 | Garwood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael G. Garwood (Medina, Minnesota); Clifford R. Jack, Jr. (Rochester, Minnesota); Joseph F Poduslo (Rochester, Minnesota); Thomas M. Wengenack (Rochester, Minnesota) |
| ASSIGNEE(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota); REGENTS OF THE UNIVERSITY OF MINNESOTA (St. Paul, Michigan) |
| INVENTOR(S) | Michael G. Garwood (Medina, Minnesota); Clifford R. Jack, Jr. (Rochester, Minnesota); Joseph F Poduslo (Rochester, Minnesota); Thomas M. Wengenack (Rochester, Minnesota) |
| ABSTRACT | Amyloid plaque in the brain of a subject is imaged in an MRI system with or without the use of a contrast agent. Contrast is achieved using a spin-echo pulse sequence that is both respiratory gated and cardiac gated to reduce motion artifacts at the very high image resolution required to see plaque. A preparatory pulse sequence is used to insure longitudinal magnetization remains constant for all the acquired views even if the effective TR changes during the scan due to irregular breathing. |
| FILED | Tuesday, June 28, 2005 |
| APPL NO | 11/631581 |
| ART UNIT | 3777 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/4088 (20130101) A61B 5/7285 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320478 | Olcott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter D. Olcott (Stanford, California); Craig S. Levin (Palo Alto, California); Sanjiv Sam Gambhir (Portola Valley, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Peter D. Olcott (Stanford, California); Craig S. Levin (Palo Alto, California); Sanjiv Sam Gambhir (Portola Valley, California) |
| ABSTRACT | Simultaneous dual-isotope positron emission tomography (PET) is used to improve disease evaluation. Two distinct molecular probes are simultaneously provided to the imaging target. One of the probes is labeled with a radionuclide that emits positrons to provide double coincidence events in PET. The other probe is labeled with a radionuclide that emits positrons+prompt gammas to provide triple coincidence events in PET. One of the probes is a metabolic probe, and the other probe is a selective probe that includes a ligand or antibody that is biologically responsive to receptor/antigen status. A PET system is employed that can provide simultaneous double coincidence and triple coincidence PET images. The resulting images provide simultaneous metabolic imaging and receptor/antigen imaging. Applications include disease evaluation, such as cancer staging (e.g., for breast cancer, prostate cancer, etc.). |
| FILED | Monday, April 30, 2012 |
| APPL NO | 14/113142 |
| ART UNIT | 3777 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Original (OR) Class A61B 6/508 (20130101) A61B 6/5235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320491 | Konofagou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Jean Provost (New York, New York); Jianwen Luo (New York, New York); Stanley J. Okrasinski, III (New York, New York); Stéphane Thiébaut (Antony, France); Vu Thanh-Hieu Nguyen (Lentigny, Switzerland) |
| ABSTRACT | Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds. |
| FILED | Friday, October 18, 2013 |
| APPL NO | 14/057685 |
| ART UNIT | 3777 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/08 (20130101) A61B 8/483 (20130101) A61B 8/0883 (20130101) Original (OR) Class A61B 8/4281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320719 | Messersmith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Kvar C. L. Black, IV (Evanston, Illinois); Ji Yi (Evanston, Illinois); Jose G. Rivera (Waukegan, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Kvar C. L. Black, IV (Evanston, Illinois); Ji Yi (Evanston, Illinois); Jose G. Rivera (Waukegan, Illinois) |
| ABSTRACT | The present invention provides nanoparticles including a metallic core having a length along each axis of from 1 to 100 nanometers and a coating disposed on at least part of the surface of the metallic core, wherein the coating comprises polydopamine, along with methods for making and using such nanoparticles. The metallic core may be gold, silver or iron oxide and the polydopamine coating may have other substances bound to it, such as silver, targeting ligands or antibodies, or other therapeutic or imaging contrast agents. The disclosed nanoparticles can be targeted to cells for treating cancer or bacterial infections, and for use in diagnostic imaging. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/294636 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Original (OR) Class A61K 9/0092 (20130101) A61K 9/5094 (20130101) A61K 31/69 (20130101) A61K 33/00 (20130101) A61K 33/26 (20130101) A61K 33/38 (20130101) A61K 39/40 (20130101) A61K 39/39558 (20130101) A61K 41/0052 (20130101) A61K 41/0057 (20130101) A61K 45/06 (20130101) A61K 47/48861 (20130101) A61K 49/1857 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Peptides C07K 16/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/4795 (20130101) G01N 33/587 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320722 | Hurley |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Thomas D. Hurley (Indianapolis, Indiana) |
| ABSTRACT | Described herein are compositions and methods for the treatment of cancer, and in particular cancers characterized by a high level of ALD3H1 activity, which is associated with chemoresistance to cancer chemotherapeutic agents that are degraded by ALD3H1. The compositions described herein act as competitive inhibitors of ALD3H1 and thereby reduce breakdown of chemotherapeutics by this enzyme, and increase their efficacy for cancer treatment. |
| FILED | Friday, September 26, 2014 |
| APPL NO | 14/498618 |
| ART UNIT | 1672 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/63 (20130101) A61K 31/63 (20130101) A61K 31/135 (20130101) A61K 31/136 (20130101) A61K 31/145 (20130101) Original (OR) Class A61K 31/145 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/381 (20130101) A61K 31/381 (20130101) A61K 31/426 (20130101) A61K 31/426 (20130101) A61K 31/553 (20130101) A61K 31/553 (20130101) A61K 31/635 (20130101) A61K 31/635 (20130101) A61K 31/4184 (20130101) A61K 31/4436 (20130101) A61K 31/4436 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 31/4468 (20130101) A61K 31/4468 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 31/5386 (20130101) A61K 31/5386 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320723 | Phipps et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Richard P. Phipps (Pittsford, New York); Naxin Guo (Rochester, New York); Steven Feldon (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Richard P. Phipps (Pittsford, New York); Naxin Guo (Rochester, New York); Steven Feldon (Rochester, New York) |
| ABSTRACT | The present invention relates to a methods and compositions for the treatment of and management of symptoms for thyroid eye disease. The methods include administering to a patient having thyroid eye disease an agent that interferes with hyaluronan synthesis in an amount that is effective to inhibit hyaluronan synthesis in a retro-ocular space. The pharmaceutical compositions hat includes a carrier suitable for ophthalmic delivery and an agent that interferes with hyaluronan synthesis. Combination therapies are also disclosed. |
| FILED | Tuesday, May 03, 2011 |
| APPL NO | 13/099991 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/166 (20130101) Original (OR) Class A61K 31/201 (20130101) A61K 31/403 (20130101) A61K 31/713 (20130101) A61K 31/4439 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320734 | Mahadevan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Daruka Mahadevan (Memphis, Tennessee); Emmanuelle J. Meuillet (Oro Valley, Arizona); Eugene A. Mash, Jr. (Tucson, Arizona); Vijay M. Gokhale (Tucson, Arizona); Garth Powis (Houston, Texas); Shuxing Zhang (Pearland, Texas) |
| ABSTRACT | Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein. |
| FILED | Monday, January 05, 2015 |
| APPL NO | 14/589360 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/433 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 59/90 (20130101) C07C 65/40 (20130101) C07C 233/75 (20130101) C07C 235/64 (20130101) C07C 237/42 (20130101) C07C 271/22 (20130101) C07C 311/21 (20130101) C07C 317/14 (20130101) C07C 317/18 (20130101) C07C 317/28 (20130101) C07C 317/44 (20130101) C07C 323/65 (20130101) Heterocyclic Compounds C07D 213/50 (20130101) C07D 213/74 (20130101) C07D 213/76 (20130101) C07D 213/643 (20130101) C07D 231/06 (20130101) C07D 231/12 (20130101) C07D 231/20 (20130101) C07D 231/38 (20130101) C07D 231/42 (20130101) C07D 233/20 (20130101) C07D 233/26 (20130101) C07D 233/64 (20130101) C07D 237/08 (20130101) C07D 237/18 (20130101) C07D 239/26 (20130101) C07D 239/34 (20130101) C07D 239/38 (20130101) C07D 239/42 (20130101) C07D 239/52 (20130101) C07D 261/08 (20130101) C07D 261/20 (20130101) C07D 263/32 (20130101) C07D 263/42 (20130101) C07D 263/56 (20130101) C07D 271/10 (20130101) C07D 271/113 (20130101) C07D 277/52 (20130101) C07D 277/64 (20130101) C07D 285/12 (20130101) C07D 285/125 (20130101) C07D 285/135 (20130101) C07D 295/26 (20130101) C07D 295/135 (20130101) C07D 295/192 (20130101) C07D 333/38 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 413/06 (20130101) C07D 417/06 (20130101) C07D 417/10 (20130101) C07D 417/12 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320736 | Kutikov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Institute for Cancer Research (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Kutikov (Voorhees, New Jersey); Vladimir Kolenko (Philadelphia, Pennsylvania); Seth M. Cohen (San Marcos, California); Robert G. Uzzo (Ambler, Pennsylvania); Ervin Teper (Huntington Valley, Pennsylvania) |
| ABSTRACT | The invention provides zinc chelating agents and formulations thereof that deplete XIAP in cancer cells and sensitize the cells to apoptosis-inducing agents. The invention provides methods for sensitizing apoptosis-resistant cancer cells to apoptosis-inducing agents, as well as methods for treating a subject with a combined therapy of a zinc chelating agent and an apoptosis-inducing agent. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 14/610044 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Original (OR) Class A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 38/191 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09320741 — Compositions and methods for treating neoplasia, inflammatory disease and other disorders
| US 09320741 | Bradner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | James Elliott Bradner (Weston, Massachusetts); Jun Qi (Sharon, Massachusetts) |
| ABSTRACT | The invention features compositions and methods for treating or preventing a neoplasia. More specifically, the invention provides compositions and methods for disrupting the interaction of a BET family polypeptide comprising a bromodomain with chromatin (e.g., disrupting a bromodomain interaction with an acetyl-lysine modification present on a histone N-terminal tail). |
| FILED | Tuesday, September 30, 2014 |
| APPL NO | 14/502840 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/551 (20130101) Original (OR) Class A61K 31/5517 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 495/12 (20130101) C07D 495/14 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320749 | Thyagarajan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| INVENTOR(S) | Baskaran Thyagarajan (Laramie, Wyoming); Padmamalini Baskaran (Laramie, Wyoming) |
| ABSTRACT | A magnetic nanoparticles including a TRPV1 agonist, as well as methods of preparation and use, are described herein. A magnetically responsive pharmaceutical can include a core region having a magnetic nanoparticle (MNPs) and a TRPV1 protein agonist. Further, an exterior coating comprising a polymer can be formed around the core region. The magnetically responsive pharmaceutical can be administered to a recipient and directed to a target region using an external magnetic field. |
| FILED | Tuesday, January 06, 2015 |
| APPL NO | 14/590124 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/23 (20130101) A61K 31/165 (20130101) A61K 31/231 (20130101) A61K 31/357 (20130101) A61K 31/7034 (20130101) Original (OR) Class A61K 41/0052 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320750 | Yaffe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael B. Yaffe (Somerville, Massachusetts); Michael Jungho Lee (Cambridge, Massachusetts); Paula T. Hammond (Newton, Massachusetts); Stephen W. Morton (Somerville, Massachusetts) |
| ABSTRACT | Time-staggered inhibition of EGFR, in combination with DNA damaging agents, is a useful therapeutic strategy for treating cancers, particularly drug resistant cancers such as a subset of triple-negative tumors, particularly those with high basal levels of phosphorylated EGFR. The staggered therapy was also demonstrated to be applicable to other types of tumors, especially lung cancers, which contain either high levels of phosphorylated wild-type EGFR or mutations within EGFR itself. EGFR inhibition dramatically sensitizes cancer cells to DNA damage if the drugs are given sequentially, but not simultaneously. The first drug must be administered in a dosage and for a period of time sufficient for the dynamic network rewiring of an oncogenic signature maintained by active EGFR signaling to unmask an apoptotic process that involves activation of caspase-8. |
| FILED | Tuesday, April 23, 2013 |
| APPL NO | 13/869012 |
| ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/704 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320751 | Mylonakis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Eleftherios Mylonakis (Boston, Massachusetts); Edward Holson (Newton Highlands, Massachusetts); Frederick M. Ausubel (Newton, Massachusetts) |
| ABSTRACT | Methods of treating a fungal infection in a subject, the method comprising administering to the subject a modified saponin. |
| FILED | Thursday, February 12, 2015 |
| APPL NO | 14/620542 |
| ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) Original (OR) Class A61K 31/7048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320757 | Exner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Agata Exner (Westlake, Ohio); Tianyi Krupka (Westlake, Ohio); Brent Weinberg (Cleveland Heights, Ohio); John Haaga (Chagrin Falls, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Agata Exner (Westlake, Ohio); Tianyi Krupka (Westlake, Ohio); Brent Weinberg (Cleveland Heights, Ohio); John Haaga (Chagrin Falls, Ohio) |
| ABSTRACT | A method for treating a neoplastic disorder in a subject includes administering to the neoplastic cells a neoplastic cell-sensitizing composition including a poly(ethylene oxide)-poly(propylene oxide) copolymer. The poly(ethylene oxide)-poly(propylene oxide) copolymer can sensitize the neoplastic cells to hyperthermia. Energy can be applied to the neoplastic cells to heat and ablate the cells. |
| FILED | Thursday, November 29, 2007 |
| APPL NO | 11/947375 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/765 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320777 | Cox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George N. Cox (Louisville, Colorado); Christie M. Orschell (Indianapolis, Indiana) |
| ASSIGNEE(S) | Bolder Biotechnology, Inc. (Boulder, Colorado) |
| INVENTOR(S) | George N. Cox (Louisville, Colorado); Christie M. Orschell (Indianapolis, Indiana) |
| ABSTRACT | Methods and compositions for the use of long-acting hematopoietic factor protein analogs for accelerating hematopoietic recovery in subjects who have been or will be exposed to radiation are disclosed. |
| FILED | Monday, May 14, 2012 |
| APPL NO | 13/471293 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/27 (20130101) A61K 38/193 (20130101) Original (OR) Class A61K 38/2073 (20130101) A61K 47/48215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320786 | Desai |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanjay A. Desai (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Sanjay A. Desai (Potomac, Maryland) |
| ABSTRACT | The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula (I): Q-Y—R1—R2 (I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula (I) in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions. |
| FILED | Wednesday, April 11, 2012 |
| APPL NO | 14/111256 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/50 (20130101) A61K 31/422 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/495 (20130101) A61K 31/498 (20130101) A61K 31/501 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/554 (20130101) A61K 31/554 (20130101) A61K 31/4741 (20130101) A61K 39/015 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/84 (20130101) C07D 241/44 (20130101) C07D 263/57 (20130101) C07D 277/54 (20130101) C07D 281/16 (20130101) C07D 409/04 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) C07D 417/06 (20130101) C07D 491/048 (20130101) C07D 498/04 (20130101) C07D 513/04 (20130101) Peptides C07K 14/445 (20130101) C07K 16/205 (20130101) C07K 2319/21 (20130101) C07K 2319/43 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320807 | Patil et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Rameshwar Patil (Los Angeles, California); Eggehard Holler (Los Angeles, California); Keith L. Black (Los Angeles, California); Julia Y. Ljubimova (Studio City, California) |
| ABSTRACT | The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety. The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety. |
| FILED | Wednesday, February 12, 2014 |
| APPL NO | 14/179195 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/425 (20130101) A61K 47/482 (20130101) Original (OR) Class A61K 47/48061 (20130101) A61K 47/48338 (20130101) A61K 47/48384 (20130101) A61K 47/48561 (20130101) A61K 47/48692 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320810 | Ruoslahti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| INVENTOR(S) | Erkki Ruoslahti (Rancho Santa Fe, California); Kimmo Porkka (Helsinki, Finland); Sven Christian (San Diego, California) |
| ABSTRACT | The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided. |
| FILED | Wednesday, October 30, 2013 |
| APPL NO | 14/067858 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/48246 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) C07K 14/4702 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320814 | Vetro |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Joseph A. Vetro (Logan, Iowa) |
| ABSTRACT | The present invention provides compositions and methods for delivering nucleic acid molecules to a cell. |
| FILED | Thursday, November 01, 2012 |
| APPL NO | 13/666021 |
| ART UNIT | 1674 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 48/0041 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320826 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bruce P. Lee (Madison, Wisconsin); Jeffrey L. Dalsin (Verona, Wisconsin); John L. Murphy (Verona, Wisconsin); Laura Vollenweider (Lodi, Wisconsin); Arinne N. Lyman (Fitchburg, Wisconsin); Fangmin Xu (Sudbury, Massachusetts); Jediah White (Madison, Wisconsin); William D. Lew (Mendota Heights, Minnesota); Michael Brodie (Belleville, Wisconsin) |
| ASSIGNEE(S) | KENSEY NASH CORPORATION (Exton, Pennsylvania) |
| INVENTOR(S) | Bruce P. Lee (Madison, Wisconsin); Jeffrey L. Dalsin (Verona, Wisconsin); John L. Murphy (Verona, Wisconsin); Laura Vollenweider (Lodi, Wisconsin); Arinne N. Lyman (Fitchburg, Wisconsin); Fangmin Xu (Sudbury, Massachusetts); Jediah White (Madison, Wisconsin); William D. Lew (Mendota Heights, Minnesota); Michael Brodie (Belleville, Wisconsin) |
| ABSTRACT | The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins. |
| FILED | Wednesday, November 09, 2011 |
| APPL NO | 13/292527 |
| ART UNIT | 3773 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/001 (20130101) A61L 24/0005 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 24/046 (20130101) A61L 24/046 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320832 | Joseph et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jose P. Joseph (Palo Alto, California); Pablo E. Garcia (Menlo Park, California); Karen F. Shakespear (San Francisco, California); Sarah Young (Menlo Park, California); Janus A. J. Haagensen (Menlo Park, California); Sanjeev Dutta (Los Altos, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Jose P. Joseph (Palo Alto, California); Pablo E. Garcia (Menlo Park, California); Karen F. Shakespear (San Francisco, California); Sarah Young (Menlo Park, California); Janus A. J. Haagensen (Menlo Park, California); Sanjeev Dutta (Los Altos, California) |
| ABSTRACT | An implantable catheter is provided that may be disinfected without removal from the body of a patient, using an electrochemical method to generate an electric field on the catheter surface and thus destroy microorganisms in a biofilm that is present or forming. A catheter system includes the implantable catheter and a voltage source that is operably connected to electrodes on or embedded in the exterior and optionally the interior catheter surface. Methods are also provided for disinfecting the implantable catheter in vivo and for detecting or confirming the presence of a pathogenic biofilm thereon. |
| FILED | Wednesday, June 20, 2012 |
| APPL NO | 13/528788 |
| ART UNIT | 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/03 (20130101) A61L 29/04 (20130101) Original (OR) Class A61L 29/14 (20130101) A61L 2202/11 (20130101) A61L 2202/24 (20130101) A61L 2400/18 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0017 (20130101) A61M 2025/0019 (20130101) A61M 2025/0056 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321049 | Sturmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Liquid Logic, Inc. (San Diego, California) |
| ASSIGNEE(S) | ADVANCED LIQUID LOGIC, INC. (San Diego, California) |
| INVENTOR(S) | Ryan A. Sturmer (Durham, North Carolina); Michael G. Pollack (Durham, North Carolina); Vamsee K. Pamula (Cary, North Carolina); Vijay Srinivasan (Cary, North Carolina); Philip Y. Paik (Chula Vista, California) |
| ABSTRACT | A method, circuit and apparatus for detecting capacitance on a droplet actuator, inter alia, for determining the presence, partial presence or absence of a droplet at an electrode on a droplet actuator by: (a) providing a droplet actuator comprising: (i) a substrate comprising electrodes arranged on the substrate for conducting droplet operations on a surface of the substrate; (ii) a capacitance detection circuit for detecting capacitance at the droplet operations surface at one or more of the electrodes; (b) detecting capacitance at the droplet operations surface at one or more of the electrodes; and (c) determining from the capacitance the presence, partial presence or absence of a droplet at the droplet operations surface at the electrode. |
| FILED | Wednesday, July 23, 2014 |
| APPL NO | 14/338889 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2300/0636 (20130101) B01L 2300/0645 (20130101) B01L 2300/0809 (20130101) B01L 2400/0427 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/22 (20130101) G01N 27/223 (20130101) G01N 27/227 (20130101) G01N 2203/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321737 | Roninson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SENEX BIOTECHNOLOGY INC (Columbia, South Carolina) |
| ASSIGNEE(S) | SENEX BIOTECHNOLOGY INC (Columbia, South Carolina) |
| INVENTOR(S) | Igor B Roninson (Lexington, South Carolina); Donald C Porter (Columbia, South Carolina); Mark P Wentland (Watervilet, New York) |
| ABSTRACT | The invention relates to the compounds and methods for inhibiting the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to compounds and methods for inhibiting the CDKI pathway for studies of and intervention in senescence-related and other CDKI-related diseases. The invention provides new compounds having improved solubility and/or potency, and methods for their use. In various aspects, the invention relates to the treatment of cancer. The invention provides methods for chemoprevention and prevention of tumor recurrence or metastasis. The invention further provides diagnostic techniques for treatment for certain cancer types. The invention utilizes specific inhibitors of CDK8/19 and/or measurement of CDK8 levels in a patient. |
| FILED | Friday, February 01, 2013 |
| APPL NO | 13/757682 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 31/517 (20130101) A61K 31/535 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 239/94 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321743 | Piomelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Universita Degli Studi Di Urbino “Carlo Bo” (Urbino, Italy); Universita Degli Studi Di Parma (Parma, Italy) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Universita Degli Studi Di Parma (Parma, Italy); Universita Degli Studi Di Urbino “Carlo Bo” (Urbino, Italy) |
| INVENTOR(S) | Daniele Piomelli (Irvine, California); Giorgio Tarzia (Petriano, Italy); Marco Mor (Ghedi, Italy); Andrea Duranti (Urbino, Italy); Andrea Tontini (Pesaro, Italy) |
| ABSTRACT | Compounds and pharmaceutical compositions are contemplated that inhibit N-acyl-ethanolamine-hydrolyzing acid amidase (NAAA) to so increase the concentration of the substrate of NAAA, palmitoylethanolamide (PEA). NAAA inhibition is contemplated to be effective to alleviate conditions associated with a reduced concentration of PEA. Among other uses, various NAAA inhibitors are especially contemplated as therapeutic agents in the treatment of inflammatory diseases. |
| FILED | Monday, May 20, 2013 |
| APPL NO | 13/898225 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/195 (20130101) A61K 31/337 (20130101) A61K 31/365 (20130101) Heterocyclic Compounds C07D 305/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321772 | Dar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Mount Sinai School of Medicine (New York, New York) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Icahn School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Arvin C. Dar (San Francisco, California); Tirtha K. Das (New York, New York); Martin Sos (San Francisco, California); Trever G. Bivona (San Francisco, California); Kevan M. Shokat (San Francisco, California); Ross L. Cagan (New York, New York) |
| ABSTRACT | Presented herein are novel therapeutic compounds and methods of using the same for the treatment of cancers. |
| FILED | Tuesday, February 25, 2014 |
| APPL NO | 14/189742 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321799 | Prakash et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| INVENTOR(S) | Thazha P. Prakash (Carlsbad, California); Punit P. Seth (Carlsbad, California); Eric E. Swayze (Encinitas, California) |
| ABSTRACT | The present invention provides modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom. More particularly, the present invention provides modified nucleosides and analogs thereof that are useful for incorporation at the terminus of an oligomeric compound. Such oligomeric compounds can also be included in a double stranded composition. In some embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. |
| FILED | Friday, February 20, 2015 |
| APPL NO | 14/627960 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) Original (OR) Class C07H 19/20 (20130101) C07H 19/067 (20130101) C07H 19/167 (20130101) C07H 21/00 (20130101) C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 15/1137 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/318 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321802 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia) |
| ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia) |
| INVENTOR(S) | Shunlin Ren (Richmond, Virginia); William M. Pandak (Richmond, Virginia) |
| ABSTRACT | The sulfated oxysterol 5-cholesten-3β, 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an agent to lower intracellular and serum cholesterol and/or triglycerides, and to prevent or treat lipid accumulation-associated inflammation and conditions associated with such inflammation. Methods which involve the use of this sulfated oxysterol to treat conditions associated with high cholesterol and/or high triglycerides and/or inflammation (e.g. hypercholesterolemia, hypertriglyceridemia, non-alcoholic fatty liver diseases, atherosclerosis, etc.) are also provided. |
| FILED | Thursday, February 14, 2013 |
| APPL NO | 13/766839 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Steroids C07J 9/00 (20130101) C07J 31/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321803 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Xi Jiang (Cincinnati, Ohio); Ming Tan (Cincinnati, Ohio); Xufu Zhang (Guangdong, China PRC) |
| ABSTRACT | A composition for use in inhibiting the binding of a Norovirus to the histo-blood group antigen on the surface of epithelia is disclosed. The composition may contain a therapeutically effective amount of a binding-inhibiting compound and a carrier and/or excipient. The compounds may competitively bind a Norovirus that has the capability of binding with the histo-blood group antigens of secretor blood type, including A, B, AB, and O blood types. The compositions may be administered to a human prior to or after infection by a Norovirus, to prevent, ameliorate, or reduce the effects of an infection. |
| FILED | Wednesday, July 09, 2014 |
| APPL NO | 14/326894 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Steroids C07J 3/00 (20130101) C07J 7/002 (20130101) C07J 7/0005 (20130101) C07J 9/00 (20130101) C07J 9/005 (20130101) C07J 41/0005 (20130101) C07J 41/0016 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321811 | Linington et al. |
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| FUNDED BY |
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| APPLICANT(S) | Roger Linington (Santa Cruz, California); Laura Sanchez (Santa Cruz, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Roger Linington (Santa Cruz, California); Laura Sanchez (Santa Cruz, California) |
| ABSTRACT | A novel structural class of highly N-methylated linear lipopeptide compounds useful for the treatment of parasitic disease. |
| FILED | Friday, April 18, 2014 |
| APPL NO | 14/256154 |
| ART UNIT | 1676 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321813 | Walter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark R. Walter (Birmingham, Alabama); Peter A. Barry (Sacramento, California) |
| ASSIGNEE(S) | UAB Research Foundation (Birmingham, Alabama); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mark R. Walter (Birmingham, Alabama); Peter A. Barry (Sacramento, California) |
| ABSTRACT | The present invention provides methods and compositions for treating and/or preventing a cytomegalovirus infection in a subject, comprising administering to the subject an effective amount of a cytomegalovirus interleukin-10 (IL-10) protein modified to have reduced functional activity while retaining immunogenicity. The present invention further provides nucleic acid molecules encoding a cytomegalovirus IL-10 protein or fragment thereof of this invention as well as vectors comprising such nucleic acids. Also provided herein are neutralizing antibodies that specifically bind cmvIL-10. |
| FILED | Tuesday, March 27, 2012 |
| APPL NO | 14/008484 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/12 (20130101) A61K 39/245 (20130101) A61K 2039/53 (20130101) A61K 2039/545 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 16/088 (20130101) C07K 16/244 (20130101) C07K 2317/76 (20130101) C07K 2319/02 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16122 (20130101) C12N 2710/16133 (20130101) C12N 2710/16134 (20130101) C12N 2710/16162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321822 | Wang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ping Wang (Roslyn, New York) |
| ASSIGNEE(S) | The Feinstein Institute for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Ping Wang (Roslyn, New York) |
| ABSTRACT | Provided are methods of treating a mammal undergoing sepsis or at risk for sepsis. Also provided are methods of preventing or treating a physiologic effect of sepsis in a mammal. Additionally provided is the use of milk fat globule epidermal growth factor-factor VIII (MFG-E8) for the manufacture of a medicament for preventing or treating a physiologic effect of sepsis in a mammal, and the use of milk fat globule epidermal growth factor-factor VIII (MFG-E8) for the treatment of a mammal having sepsis or at risk for sepsis. |
| FILED | Friday, May 12, 2006 |
| APPL NO | 11/920304 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321826 | Camire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Rodney M. Camire (Sicklerville, New Jersey); Matthew W. Bunce (Havertown, Pennsylvania); Mettine H. A. Bos (Amsterdam, Netherlands) |
| ABSTRACT | Factor V peptides and methods of use thereof are disclosed. |
| FILED | Friday, April 11, 2014 |
| APPL NO | 14/250840 |
| ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/36 (20130101) A61K 45/06 (20130101) Peptides C07K 14/745 (20130101) Original (OR) Class C07K 2319/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321828 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Deshui Zhang (Woodland, California); Ning Huang (Davis, California); Diane Phuong Nguyen (Elkgrove, California); Paula Bryan (Dublin, California) |
| ASSIGNEE(S) | Ventria Bioscience Inc. (Fort Collins, Colorado) |
| INVENTOR(S) | Deshui Zhang (Woodland, California); Ning Huang (Davis, California); Diane Phuong Nguyen (Elkgrove, California); Paula Bryan (Dublin, California) |
| ABSTRACT | Disclosed are compositions and methods of making non-glycosylated transferrin protein in transgenic monocot plants. |
| FILED | Friday, May 06, 2011 |
| APPL NO | 13/102966 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/40 (20130101) Peptides C07K 14/79 (20130101) Original (OR) Class C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321829 | Ahmed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rafi Ahmed (Atlanta, Georgia); Jens Wrammert (Decatur, Georgia); Patrick C. Wilson (Chicago, Illinois) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Rafi Ahmed (Atlanta, Georgia); Jens Wrammert (Decatur, Georgia); Patrick C. Wilson (Chicago, Illinois) |
| ABSTRACT | Antibodies that specifically bind influenza virus hemagglutinin A (HA), and antigen binding fragments thereof are disclosed herein. In several embodiments, these antibodies are broadly neutralizing. Nucleic acids encoding these monoclonal antibodies, vectors including these nucleic acids, and host cells transformed with these vectors are also disclosed. Compositions are disclosed that include these antibodies, antigen binding fragments, nucleic acids, vectors and host cells. Method of using these antibodies, and antigen binding fragments, nucleic acids, vectors and host cells, such as for diagnosis and treatment of an influenza virus infection are also provided. |
| FILED | Thursday, October 18, 2012 |
| APPL NO | 14/350632 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2469/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321834 | Gutierrez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leidos, Inc. (Reston, Virginia); The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | LEIDOS, INC. (Reston, Virginia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia) |
| INVENTOR(S) | Gabriel M. Gutierrez (Reston, Virginia); James Pannucci (Reston, Virginia); Amy Noe (Reston, Virginia); Steve Chienwen Huang (Reston, Virginia); Scott Winram (Reston, Virginia); Annie Xiaoyan Mo (Bethesda, Maryland) |
| ABSTRACT | This disclosure provides antibodies that are useful for preventing and/or treating malaria. The epitope to which the antibodies bind is in close proximity to the conserved proteolytic cleavage site of P. falciparum circumsporozoite protein (CSP), and the antibodies provided in this disclosure can prevent cleavage and inhibit P. falciparum sporozoites from invading the liver. |
| FILED | Thursday, December 05, 2013 |
| APPL NO | 14/097799 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) A61K 39/39575 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/205 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321990 | Berns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael W. Berns (Irvine, California); Thoru Pederson (Worchester, Massachusetts); Elliot Botvinick (Irvine, California); Linda Zhixia Shi (Vista, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Michael W. Berns (Irvine, California); Thoru Pederson (Worchester, Massachusetts); Elliot Botvinick (Irvine, California); Linda Zhixia Shi (Vista, California) |
| ABSTRACT | This invention relates to optomechanical systems and methods for altering, modifying or disrupting a target object. Such systems and methods are used for, for example, ablating the endogenous nucleus in a cell. |
| FILED | Friday, September 16, 2011 |
| APPL NO | 13/234986 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Original (OR) Class C12M 47/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) G01N 2015/149 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/12 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321992 | Dennis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James E. Dennis (Cleveland Heights, Ohio); Arnold I. Caplan (Cleveland Heights, Ohio); Nir Cohen (Tel Aviv, Israel) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | James E. Dennis (Cleveland Heights, Ohio); Arnold I. Caplan (Cleveland Heights, Ohio); Nir Cohen (Tel Aviv, Israel) |
| ABSTRACT | In certain aspects, the invention relates to cell delivery compositions comprising a chondrogenic cell and a targeting moiety. Such compositions may be used, for example, in administering a targeted cell therapy to a subject. |
| FILED | Friday, June 13, 2003 |
| APPL NO | 10/461887 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0006 (20130101) C12N 5/0655 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321994 | Betancourt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WibiWorks Therapeutics, Inc. (San Diego, California) |
| ASSIGNEE(S) | COMMENCE BIO, INC. (Sparks, Maryland) |
| INVENTOR(S) | Aline Betancourt (La Jolla, California) |
| ABSTRACT | Novel MSC stem-cell culture and therapy methods and culture medium compositions for the purpose of inducing, activating, or priming discrete uniform cell phenotypes to selectively promote or suppress inflammation and immunity, yielding polarized, primed, activated, or induced cells used in cell-based therapy. |
| FILED | Friday, May 22, 2015 |
| APPL NO | 14/720603 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2500/92 (20130101) C12N 2501/14 (20130101) C12N 2501/24 (20130101) C12N 2501/25 (20130101) C12N 2501/58 (20130101) C12N 2501/2304 (20130101) C12N 2501/2313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322006 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); John Paul Guilinger (Ridgway, Colorado); Vikram Pattanayak (Cambridge, Massachusetts) |
| ABSTRACT | Engineered nucleases are promising tools for genome manipulation and determining off-target cleavage sites of these enzymes is of great interest. We developed an in vitro selection method that interrogates 1011 DNA sequences for their ability to be cleaved by nucleases. The method revealed hundreds of thousands of DNA sequences that can be cleaved in vitro by two ZFNs, CCR5-224 and VF2468, which target the endogenous human CCR5 and VEGF-A genes, respectively. Analysis of the identified sites in cultured human cells revealed CCR5-224-induced mutagenesis at nine off-target loci. Similarly, we observed 31 off-target sites cleaved by VF2468 in cultured human cells. Our findings establish an energy compensation model of ZFN specificity in which excess binding energy contributes to off-target ZFN cleavage and suggest strategies for the improvement of future nuclease design. It was also observed that TALENs can achieve cleavage specificity similar to or higher than that observed in ZFNs. |
| FILED | Monday, June 30, 2014 |
| APPL NO | 14/320271 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/6802 (20130101) C12Q 1/6802 (20130101) C12Q 1/6874 (20130101) C12Q 2521/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322015 | Feinberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark W. Feinberg (Newton, Massachusetts); Basak Icli (Wellesley, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mark W. Feinberg (Newton, Massachusetts); Basak Icli (Wellesley, Massachusetts) |
| ABSTRACT | Methods for promoting angiogenesis, and for diagnosing the presence or risk of developing disorders associated with impaired angiogenesis or blood flow to a tissue in the body, using microRNA-26a (miR-26a). |
| FILED | Friday, March 09, 2012 |
| APPL NO | 14/003886 |
| ART UNIT | 1674 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322022 | Karanja et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Kenneth Karanja (Pasadena, California); Martin E. Budd (Pasadena, California); Judith L. Campbell (Sierra Madre, California) |
| ABSTRACT | Inhibition of DNA2 in Fanconi anemia (FA) cells remedies the over-resection of DNA, thereby stabilizing the FA cells. Inhibition of DNA2 in FA cells allows for safe treatment of cancers in FA patients, a decrease in the lethality of FA cells, a decrease in bone marrow failure of FA patients, and a means for decreasing the incidence of cancer for FA patients. |
| FILED | Tuesday, October 21, 2014 |
| APPL NO | 14/520318 |
| ART UNIT | 1674 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) Enzymes C12Y 306/04012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322039 | Smolke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Christina D. Smolke (Menlo Park, California); Kristy M. Hawkins (Oakland, California) |
| ABSTRACT | The present invention relates to host cells that produce compounds that are characterized as benzylisoquinolines, as well as select precursors and intermediates thereof. The host cells comprise one, two or more heterologous coding sequences wherein each of the heterologous coding sequences encodes an enzyme involved in the metabolic pathway of a benzylisoquinoline, or its precursors or intermediates from a starting compound. The invention also relates to methods of producing the benzylisoquinoline, as well as select precursors and intermediates thereof by culturing the host cells under culture conditions that promote expression of the enzymes that produce the benzylisoquinoline or precursors or intermediates thereof. |
| FILED | Thursday, February 05, 2015 |
| APPL NO | 14/614484 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0022 (20130101) C12N 9/0059 (20130101) C12N 9/88 (20130101) C12N 9/1007 (20130101) C12N 9/1096 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/24 (20130101) C12P 13/001 (20130101) C12P 17/12 (20130101) Original (OR) Class C12P 17/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322047 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Taehyun Park (Baton Rouge, Louisiana); Daniel Sang-Won Park (Baton Rouge, Louisiana); Sudheer D Rani (Baton Rouge, Louisiana); Michael C Murphy (Baton Rouge, Louisiana); Dimitris E Nikitopoulos (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Taehyun Park (Baton Rouge, Louisiana); Daniel Sang-Won Park (Baton Rouge, Louisiana); Sudheer D Rani (Baton Rouge, Louisiana); Michael C Murphy (Baton Rouge, Louisiana); Dimitris E Nikitopoulos (Baton Rouge, Louisiana) |
| ABSTRACT | A device and methods are provided for efficient and quick capture of target cells through a main microchannel having capture elements immobilized thereon and manipulating a velocity profile of a sample as it passes through the main microchannel. The cell capture device may have a main microchannel with a depth slightly larger than the diameter of the target cells and a plurality of side microchannels. The side microchannels may have a depth smaller than the diameter of the target cells. The device and methods may be used for early cancer detection. |
| FILED | Friday, October 19, 2012 |
| APPL NO | 13/656295 |
| ART UNIT | 1677 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2200/0668 (20130101) B01L 2300/0816 (20130101) B01L 2300/0858 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322049 | Sauve et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Anthony Sauve (New Rochelle, New York); Ping Xu (Brynmawr, Pennsylvania) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Anthony Sauve (New Rochelle, New York); Ping Xu (Brynmawr, Pennsylvania) |
| ABSTRACT | The invention provides a method of increasing a deacetylated activity of SIRT6 by contacting SIRT6 with an agent that binds SIRT6 and reduces the Km of SIRT6 for a substrate, thereby increasing the deacetylase activity of SIRT6. The invention also provides compounds of the formulas (II) and (III). |
| FILED | Tuesday, December 14, 2010 |
| APPL NO | 13/516198 |
| ART UNIT | 1673 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91142 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322057 | Benkovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J Benkovic (State College, Pennsylvania); Frank Salinas (Wheaton, Illinois) |
| ABSTRACT | A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems. |
| FILED | Monday, December 16, 2013 |
| APPL NO | 14/107733 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1027 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2521/507 (20130101) C12Q 2521/513 (20130101) C12Q 2527/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322058 | Benkovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J Benkovic (State College, Pennsylvania); Frank Salinas (Wheaton, Illinois) |
| ABSTRACT | A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems. |
| FILED | Friday, May 02, 2014 |
| APPL NO | 14/268444 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1027 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2521/507 (20130101) C12Q 2521/513 (20130101) C12Q 2527/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322059 | Benkovic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Stephen J Benkovic (State College, Pennsylvania); Frank Salinas (Wheaton, Illinois) |
| ABSTRACT | A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems. |
| FILED | Tuesday, June 24, 2014 |
| APPL NO | 14/313295 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1027 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 2521/507 (20130101) C12Q 2521/513 (20130101) C12Q 2527/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322064 | Ozelius et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine of Mount Sinai (New York, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); Beth Israel Medical Center (New York, New York) |
| INVENTOR(S) | Laurie Ozelius (White Plains, New York); Susan Bressman (New York, New York) |
| ABSTRACT | This invention relates generally to the THAP1 gene and mutations in this gene, as well as the THAP1 protein and mutations in this protein, that are associated with dystonia. The invention relates to the identification, isolation, cloning and characterization of the DNA sequence corresponding to the wild type and mutant THAP1 genes, as well as isolation and characterization of their transcripts and gene products. The invention further relates to methods and kits useful for detecting mutations in THAP1 that are associated with dystonia, as well as to methods and kits useful for diagnosing dystonia. The present invention also relates to therapies for treating dystonia, including gene therapeutics and protein/antibody based therapeutics. |
| FILED | Wednesday, October 23, 2013 |
| APPL NO | 14/061206 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322827 | Sindhi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rakesh Sindhi (Pittsburgh, Pennsylvania); Chethan AshokKumar (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Oregon) |
| INVENTOR(S) | Rakesh Sindhi (Pittsburgh, Pennsylvania); Chethan AshokKumar (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are methods for diagnosing or predicting B-cell rejection in a subject. In one example, for assessing transplant rejection, the method includes determining an antigen presenting index by comparing uptake of a donor antigen to uptake of a reference antigen in a biological sample obtained from the subject. In another example, for assessing GVHD, the method includes determining an antigen presenting index by comparing uptake of a recipient antigen to uptake of a reference antigen in a biological sample obtained from the subject. |
| FILED | Friday, April 08, 2011 |
| APPL NO | 13/639428 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56977 (20130101) Original (OR) Class G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322896 | Fielden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Samuel W. Fielden (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia); Xue Feng (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Samuel W. Fielden (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia); Xue Feng (Charlottesville, Virginia) |
| ABSTRACT | Systems, methods of reducing off-resonance blurring in acquired magnetic resonance imaging data. The method includes acquiring a first set of spiral interleaf data for each of one or more spiral-in/out interleaves by performing a first sampling each of one or more locations in k-space along a first redundant spiral-in/out trajectory, and acquiring a second set of spiral interleaf data for each of the one or more spiral-in/out interleaves by performing a second sampling of each of the one or more locations in the k-space along a second redundant spiral-in/out trajectory, wherein the second redundant spiral-in/out trajectory corresponds to a time-reversed trajectory of the first redundant spiral-in/out trajectory. The method may yet further include combining the first set of spiral interleaf data and the second set of spiral interleaf data with an averaging operation such as to reduce artifacts. |
| FILED | Monday, April 22, 2013 |
| APPL NO | 13/868095 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/565 (20130101) Original (OR) Class G01R 33/4824 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324486 | Hahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Seungyong Hahn (Chestnut Hill, Massachusetts); YoungJae Kim (Cambridge, Massachusetts); John Peter Voccio (West Newton, Massachusetts); Juan Bascunan (Burlington, Massachusetts); Yukikazu Iwasa (Weston, Massachusetts) |
| ABSTRACT | The present invention is a superconducting partial insulation magnet and a method for providing the same. The magnet includes a coil with a non-insulated superconducting wire winding wound around a bobbin. The coil has a first wire layer, a second wire layer substantially surrounding the first layer, and a first layer of insulating material disposed between the first wire layer and the second wire layer. Each wire layer comprises a plurality of turns, and the first layer of insulating material substantially insulates the second wire layer from the first wire layer. |
| FILED | Monday, June 17, 2013 |
| APPL NO | 13/919164 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/00 (20130101) H01F 6/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 09321015 | Jayaweera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Indira Jayaweera (Menlo Park, California); Gopala N. Krishnan (Menlo Park, California); Angel Sanjurjo (Menlo Park, California); Palitha Jayaweera (Menlo Park, California); Srinivas Bhamidi (Menlo Park, California) |
| ABSTRACT | The invention provides methods for preparing an asymmetric hollow fiber, the asymmetric hollow fibers prepared by such methods, and uses of the asymmetric hollow fibers. One method involves passing a polymeric solution through an outer annular orifice of a tube-in-orifice spinneret, passing a bore fluid though an inner tube of the spinneret, dropping the polymeric solution and bore fluid through an atmosphere over a dropping distance, and quenching the polymeric solution and bore fluid in a bath to form an asymmetric hollow fiber. |
| FILED | Wednesday, February 26, 2014 |
| APPL NO | 14/190100 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 69/087 (20130101) Original (OR) Class B01D 71/62 (20130101) B01D 2256/16 (20130101) B01D 2257/502 (20130101) B01D 2257/504 (20130101) B01D 2257/7025 (20130101) B01D 2323/12 (20130101) B01D 2325/02 (20130101) B01D 2325/04 (20130101) B01D 2325/30 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/444 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/10 (20130101) Y02C 20/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09321050 — Microfluidic ultrasonic particle separators with engineered node locations and geometries
| US 09321050 | Rose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Klint A. Rose (Alviso, California); Karl A. Fisher (Brentwood, California); Douglas A. Wajda (Urbana, Illinois); Raymond P. Mariella, Jr. (Danville, California); Christopher Bailey (Oakland, California); Dietrich Dehlinger (San Francisco, California); Maxim Shusteff (Oakland, California); Byoungsok Jung (Palo Alto, California); Kevin D. Ness (Pleasanton, California) |
| ABSTRACT | An ultrasonic microfluidic system includes a separation channel for conveying a sample fluid containing small particles and large particles, flowing substantially parallel, adjacent to a recovery fluid, with which it is in contact. An acoustic transducer produces an ultrasound standing wave, that generates a pressure field having at least one node of minimum pressure amplitude. An acoustic extension structure is located proximate to said separation channel for positioning said acoustic node off center in said acoustic area and concentrating the large particles in said recovery fluid stream. |
| FILED | Tuesday, March 17, 2015 |
| APPL NO | 14/659825 |
| ART UNIT | 3653 — Printing/Measuring and Testing |
| CURRENT CPC | Separation B01D 21/28 (20130101) B01D 21/283 (20130101) B01D 2221/10 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2200/0631 (20130101) B01L 2200/0636 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/0439 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 33/491 (20130101) G01N 33/48728 (20130101) G01N 2001/4094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321638 | Cortes-Concepcion et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Savannah River Nuclear Solutions, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Jose A. Cortes-Concepcion (Aiken, South Carolina); Donald L. Anton (Aiken, South Carolina) |
| ABSTRACT | A process in a resulting product of the process in which a hydrogen storage metal amide is modified by a ball milling process using an additive of TPP. The resulting product provides for a hydrogen storage metal amide having a coating that renders the hydrogen storage metal amide resistant to air, ambient moisture, and liquid water while improving useful hydrogen storage and release kinetics. |
| FILED | Wednesday, January 09, 2013 |
| APPL NO | 13/737131 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/001 (20130101) C01B 3/0078 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321815 | Lawton, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POET Research, Inc. (Sioux Falls, South Dakota) |
| ASSIGNEE(S) | POET Research, Inc. (Sioux Falls, South Dakota) |
| INVENTOR(S) | John Warren Lawton, Jr. (Sioux Falls, South Dakota); Jason Alan Bootsma (Sioux Falls, South Dakota); Stephen Michael Lewis (Sioux Falls, South Dakota) |
| ABSTRACT | A method of producing bioproducts from a feedstock in a system configured to produce ethanol and distillers grains from a fermentation product is disclosed. A system configured to process feedstock into a fermentation product and bioproducts including ethanol and meal is disclosed. A bioproduct produced from a fermentation product produced from a feedstock in a biorefining system is disclosed. |
| FILED | Tuesday, January 07, 2014 |
| APPL NO | 14/149555 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/425 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/16 (20130101) Y02E 50/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321968 | Bohnert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri); Galen G. Verhulst (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | George W. Bohnert (Harrisonville, Missouri); Galen G. Verhulst (Kansas City, Missouri) |
| ABSTRACT | Systems and methods for hydrocarbon extraction from hydrocarbon-containing material. Such systems and methods relate to extracting hydrocarbon from hydrocarbon-containing material employing a non-aqueous extractant. Additionally, such systems and methods relate to recovering and reusing non-aqueous extractant employed for extracting hydrocarbon from hydrocarbon-containing material. |
| FILED | Friday, February 15, 2013 |
| APPL NO | 13/768740 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/04 (20130101) C10G 1/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322013 | Nath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Pulak Nath (Los Alamos, New Mexico); Scott N. Twary (Santa Fe, New Mexico) |
| ABSTRACT | Described herein are methods and systems for harvesting, collecting, separating and/or dewatering algae using iron based salts combined with a magnetic field gradient to separate algae from an aqueous solution. |
| FILED | Tuesday, February 25, 2014 |
| APPL NO | 14/189969 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 1/12 (20130101) C12N 13/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322014 | VanderNoot et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Victoria A. VanderNoot (Pleasanton, California); Stanley Alan Langevin (Seattle, Washington); Zachary Bent (Dublin, California); Ronald F. Renzi (Tracy, California); Scott M. Ferko (Livermore, California); James L. Van De Vreugde (Livermore, California); Todd Lane (Livermore, California); Kamlesh Patel (Dulbin, California); Steven Branda (Livermore, California) |
| ABSTRACT | A system for enhancing a nucleic acid sample may include a one pump, a denaturing chamber; a microfluidic hydroxyapatite chromatography device configured for performing hydroxyapatite chromatography on the nucleic acid sample, a sample collector, and tubing connecting the pump with the denaturing chamber, the hydroxyapatite chromatography device and the sample collector such that the pump may be used to move the nucleic acid sample from the denaturing chamber to the hydroxyapatite chromatography device and then to the sample collector. |
| FILED | Wednesday, November 20, 2013 |
| APPL NO | 14/084937 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/101 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6811 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/04 (20130101) G01N 30/08 (20130101) G01N 30/66 (20130101) G01N 30/82 (20130101) G01N 30/6043 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/25 (20150115) Y10T 436/255 (20150115) Y10T 436/2575 (20150115) Y10T 436/143333 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322042 | Sapra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rajat Sapra (Pennington, New Jersey); Supratim Datta (Berkeley, California); Zhiwei Chen (El Cerrito, California); Bradley M. Holmes (Oakland, California); Blake A. Simmons (San Francisco, California); Harvey W. Blanch (San Francisco, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Sandia Corporation (Livermore, California) |
| INVENTOR(S) | Rajat Sapra (Pennington, New Jersey); Supratim Datta (Berkeley, California); Zhiwei Chen (El Cerrito, California); Bradley M. Holmes (Oakland, California); Blake A. Simmons (San Francisco, California); Harvey W. Blanch (San Francisco, California) |
| ABSTRACT | The present invention provides for a composition comprising an ionic liquid and a thermostable cellulose, and a method of hydrolyzing a cellulose, comprising: (a) providing a composition comprising a solution comprising an ionic liquid and a cellulose, and (b) introducing a thermostable cellulase to the solution, such that the cellulose is hydrolyzed by the cellulase. The present invention also provides for a Thermatoga maritima thermostable cellulase mutant with increased cellulase activity. |
| FILED | Friday, April 23, 2010 |
| APPL NO | 13/265786 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2437 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/14 (20130101) Original (OR) Class Enzymes C12Y 302/01004 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322043 | Ingram et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lonnie O. Ingram (Gainesville, Florida); Claudia C. Geddes (Raleigh, North Carolina); James J. Peterson (Archer, Florida); Michael T. Mullinnix (Gainesville, Florida); Keelnatham Shanmugam (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Lonnie O. Ingram (Gainesville, Florida); Claudia C. Geddes (Raleigh, North Carolina); James J. Peterson (Archer, Florida); Michael T. Mullinnix (Gainesville, Florida); Keelnatham Shanmugam (Gainesville, Florida) |
| ABSTRACT | The invention provides methods for treatment of feedstock to reduce the relative viscosity and promote release of fermentable sugars. |
| FILED | Thursday, March 10, 2011 |
| APPL NO | 13/583132 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 2203/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322264 | Gutierrez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Transocean Sedco Forex Ventures Limited (George Town Grand Cayman, Cayman Islands) |
| ASSIGNEE(S) | TRANSOCEAN INNOVATION LABS LTD (George Town, Cayman Islands) |
| INVENTOR(S) | Jose Gutierrez (Houston, Texas); Luis Pereira (Houston, Texas) |
| ABSTRACT | A subsea processor may be located near the seabed of a drilling site and used to coordinate operations of underwater drilling components. The subsea processor may be enclosed in a single interchangeable unit that fits a receptor on an underwater drilling component, such as a blow-out preventer (BOP). The subsea processor may issue commands to control the BOP and receive measurements from sensors located throughout the BOP. A shared communications bus may interconnect the subsea processor and underwater components and the subsea processor and a surface or onshore network. The shared communications bus may be operated according to a time division multiple access (TDMA) scheme. |
| FILED | Wednesday, October 16, 2013 |
| APPL NO | 14/055795 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 7/12 (20130101) E21B 33/063 (20130101) E21B 33/064 (20130101) E21B 47/122 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322335 | Charron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard C. Charron (West Palm Beach, Florida); William W. Pankey (Palm Beach Gardens, Florida) |
| ASSIGNEE(S) | SIEMENS ENERGY, INC. (Orlando, Florida) |
| INVENTOR(S) | Richard C. Charron (West Palm Beach, Florida); William W. Pankey (Palm Beach Gardens, Florida) |
| ABSTRACT | An exit piece (66) with an inlet throat (67) that conducts a combustion gas flow (36A) in a path (82) from a combustor (63) to an annular chamber (68) that feeds the first blade section (37) of a gas turbine (26). The exit piece further includes an outlet portion (69) that forms a circumferential segment of the annular chamber. The outlet portion interconnects with adjacent outlet portions by hinges (78A, 78B, 80A, 80B). Each hinge may have a hinge axis (82A, 82B) parallel to a centerline (21) of the turbine. Respective gas flows (36A) are configured by an assembly (60) of the exit pieces to converge on the feed chamber (68) into a uniform helical flow that drives the first blade section with minimal circumferential variations in force. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 13/834185 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/023 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/20 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/25 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322555 | LeBegue et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Jeffrey Scott LeBegue (Simpsonville, South Carolina); Patrick Benedict Melton (Horse Shoe, North Carolina); James Harold Westmoreland, III (Greer, South Carolina); James Scott Flanagan (Simpsonville, South Carolina) |
| ABSTRACT | A cap assembly for a bundled tube fuel injector includes an impingement plate and an aft plate that is disposed downstream from the impingement plate. The aft plate includes a forward side that is axially separated from an aft side. A tube passage extends through the impingement plate and the aft plate. A tube sleeve extends through the impingement plate within the tube passage towards the aft plate. The tube sleeve includes a flange at a forward end and an aft end that is axially separated from the forward end. A retention plate is positioned upstream from the impingement plate. A spring is disposed between the retention plate and the flange. The spring provides a force so as to maintain contact between at least a portion of the aft end of the tube sleeve and the forward side of the aft plate. |
| FILED | Monday, July 01, 2013 |
| APPL NO | 13/932317 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Burners F23D 14/62 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/10 (20130101) Original (OR) Class F23R 3/283 (20130101) F23R 3/286 (20130101) F23R 2900/00005 (20130101) F23R 2900/00012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322557 | Uhm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jong Ho Uhm (Simpsonville, South Carolina); Willy Steve Ziminsky (Simpsonville, South Carolina); Thomas Edward Johnson (Greer, South Carolina); William David York (Greer, South Carolina) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Jong Ho Uhm (Simpsonville, South Carolina); Willy Steve Ziminsky (Simpsonville, South Carolina); Thomas Edward Johnson (Greer, South Carolina); William David York (Greer, South Carolina) |
| ABSTRACT | A combustor includes a tube bundle that extends radially across at least a portion of the combustor. The tube bundle includes an upstream surface axially separated from a downstream surface. A plurality of tubes extends from the upstream surface through the downstream surface, and each tube provides fluid communication through the tube bundle. A baffle extends axially inside the tube bundle between adjacent tubes. A method for distributing fuel in a combustor includes flowing a fuel into a fuel plenum defined at least in part by an upstream surface, a downstream surface, a shroud, and a plurality of tubes that extend from the upstream surface to the downstream surface. The method further includes impinging the fuel against a baffle that extends axially inside the fuel plenum between adjacent tubes. |
| FILED | Thursday, January 05, 2012 |
| APPL NO | 13/343926 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Burners F23D 2209/10 (20130101) F23D 2209/20 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/283 (20130101) Original (OR) Class F23R 3/286 (20130101) F23R 2900/03044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322566 | Wenzel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Johnson Controls Technology Company (Holland, Michigan) |
| ASSIGNEE(S) | Johnson Controls Technology Company (Holland, Michigan) |
| INVENTOR(S) | Michael J. Wenzel (Oak Creek, Wisconsin); Kirk H. Drees (Cedarburg, Wisconsin) |
| ABSTRACT | Systems and methods for limiting power consumption by a heating, ventilation, and air conditioning (HVAC) subsystem of a building are shown and described. A feedback controller is used to generate a manipulated variable based on an energy use setpoint and a measured energy use. The manipulated variable may be used for adjusting the operation of an HVAC device. |
| FILED | Monday, September 22, 2014 |
| APPL NO | 14/493053 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/006 (20130101) Original (OR) Class F24F 11/0009 (20130101) F24F 2011/0075 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1923 (20130101) Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322720 | Wernsman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Bernard R. Wernsman (Jefferson Hills, Pennsylvania); Raymond J. Blasi (North Huntingdon, Pennsylvania); Bernhard R. Tittman (State College, Pennsylvania); David A. Parks (Tulsa, Oklahoma) |
| ABSTRACT | An aluminum nitride piezoelectric ultrasonic transducer successfully operates at temperatures of up to 1000° C. and fast (>1 MeV) neutron fluencies of more than 1018 n/cm2. The transducer comprises a transparent, nitrogen rich aluminum nitride (AlN) crystal wafer that is coupled to an aluminum cylinder for pulse-echo measurements. The transducer has the capability to measure in situ gamma heating within the core of a nuclear reactor. |
| FILED | Friday, February 21, 2014 |
| APPL NO | 14/186244 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/22 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322854 | Carpenter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gary D. Carpenter (Austin, Texas); Wael El-Essawy (Austin, Texas); Alexandre Peixoto Ferreira (Austin, Texas); Thomas Walter Keller (Austin, Texas); Juan C. Rubio (Austin, Texas); Michael A. Schappert (Wappingers Falls, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Gary D. Carpenter (Austin, Texas); Wael El-Essawy (Austin, Texas); Alexandre Peixoto Ferreira (Austin, Texas); Thomas Walter Keller (Austin, Texas); Juan C. Rubio (Austin, Texas); Michael A. Schappert (Wappingers Falls, New York) |
| ABSTRACT | A method of measurement using a detachable current and voltage sensor provides an isolated and convenient technique for to measuring current passing through a conductor such as an AC branch circuit wire, as well as providing an indication of an electrostatic potential on the wire, which can be used to indicate the phase of the voltage on the wire, and optionally a magnitude of the voltage. The device includes a housing that contains the current and voltage sensors, which may be a ferrite cylinder with a hall effect sensor disposed in a gap along the circumference to measure current, or alternative a winding provided through the cylinder along its axis and a capacitive plate or wire disposed adjacent to, or within, the ferrite cylinder to provide the indication of the voltage. |
| FILED | Thursday, April 19, 2012 |
| APPL NO | 13/451524 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/22 (20130101) G01R 15/142 (20130101) G01R 21/06 (20130101) Original (OR) Class G01R 33/02 (20130101) G01R 33/072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322855 | Carpenter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Gary D. Carpenter (Austin, Texas); Wael El-Essawy (Austin, Texas); Alexandre Peixoto Ferreira (Austin, Texas); Thomas Walter Keller (Austin, Texas); Juan C. Rubio (Austin, Texas); Michael A. Schappert (Wappingers Falls, New York) |
| ABSTRACT | A detachable current and voltage sensor provides an isolated and convenient device to measure current passing through a conductor such as an AC branch circuit wire, as well as providing an indication of an electrostatic potential on the wire, which can be used to indicate the phase of the voltage on the wire, and optionally a magnitude of the voltage. The device includes a housing formed from two portions that mechanically close around the wire and that contain the current and voltage sensors. The current sensor is a ferrite cylinder formed from at least three portions that form the cylinder when the sensor is closed around the wire with a hall effect sensor disposed in a gap between two of the ferrite portions along the circumference to measure current. A capacitive plate or wire is disposed adjacent to, or within, the ferrite cylinder to provide the indication of the voltage. |
| FILED | Monday, June 30, 2014 |
| APPL NO | 14/319389 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/22 (20130101) G01R 15/142 (20130101) G01R 21/06 (20130101) Original (OR) Class G01R 33/02 (20130101) G01R 33/072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324465 | Splichal, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William Francis Splichal, Jr. (San Jose, California) |
| ASSIGNEE(S) | GE-HITACHI NUCLEAR ENERGY AMERICAS LLC (Wilmington, North Carolina) |
| INVENTOR(S) | William Francis Splichal, Jr. (San Jose, California) |
| ABSTRACT | An apparatus may include two or more electrical conductors, one or more signal devices, and an analyzer. The one or more signal devices may be adapted to apply one or more signals to the two or more electrical conductors and receive one or more signals from the two or more electrical conductors. The analyzer may be adapted to determine power level in the nuclear reactor using at least one of the applied signals and at least one of the received signals. A method of determining power level in a nuclear reactor may include: measuring impedance values of two or more electrical conductors disposed in the nuclear reactor and using the measured impedance values to determine the power level. A method of operating a nuclear reactor may include: measuring the impedance values and using the measured impedance values to determine parameters of the nuclear reactor. |
| FILED | Wednesday, April 01, 2009 |
| APPL NO | 12/385200 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 17/108 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324550 | Jones |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sandia Corporation (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | David Alexander Jones (Sandia Park, New Mexico) |
| ABSTRACT | The present disclosure is directed to an ion mobility drift tube fabricated using flex-circuit technology in which every other drift electrode is on a different layer of the flex-circuit and each drift electrode partially overlaps the adjacent electrodes on the other layer. This results in a self-shielding effect where the drift electrodes themselves shield the interior of the drift tube from unwanted electro-magnetic noise. In addition, this drift tube can be manufactured with an integral flex-heater for temperature control. This design will significantly improve the noise immunity, size, weight, and power requirements of hand-held ion mobility systems such as those used for explosive detection. |
| FILED | Thursday, February 05, 2015 |
| APPL NO | 14/615263 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0022 (20130101) H01J 49/062 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324562 | Luther et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Joseph M. Luther (Boulder, Colorado); Ryan Crisp (Golden, Colorado); Matthew C. Beard (Arvada, Colorado) |
| ABSTRACT | Methods of treating nanocrystal and/or quantum dot devices are described. The methods include contacting the nanocrystals and/or quantum dots with a solution including metal ions and halogen ions, such that the solution displaces native ligands present on the surface of the nanocrystals and/or quantum dots via ligand exchange. |
| FILED | Thursday, November 12, 2015 |
| APPL NO | 14/939928 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02568 (20130101) Original (OR) Class H01L 21/02601 (20130101) H01L 21/02628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324733 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Matthew Meitl (Durham, North Carolina); Yugang Sun (Naperville, Illinois); Heung Cho Ko (Gwangju, South Korea); Andrew Carlson (Urbana, Illinois); Won Mook Choi (Gyeonggi-do, South Korea); Mark Stoykovich (Dover, New Hampshire); Hanqing Jiang (Chandler, Arizona); Yonggang Huang (Glencoe, Illinois); Ralph G. Nuzzo (Champaign, Illinois); Zhengtao Zhu (Rapid City, South Dakota); Etienne Menard (Durham, North Carolina); Dahl-Young Khang (Seoul, South Korea) |
| ABSTRACT | In an aspect, the present invention provides stretchable, and optionally printable, components such as semiconductors and electronic circuits capable of providing good performance when stretched, compressed, flexed or otherwise deformed, and related methods of making or tuning such stretchable components. Stretchable semiconductors and electronic circuits preferred for some applications are flexible, in addition to being stretchable, and thus are capable of significant elongation, flexing, bending or other deformation along one or more axes. Further, stretchable semiconductors and electronic circuits of the present invention are adapted to a wide range of device configurations to provide fully flexible electronic and optoelectronic devices. |
| FILED | Thursday, March 20, 2014 |
| APPL NO | 14/220910 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02422 (20130101) H01L 21/02628 (20130101) H01L 21/8258 (20130101) H01L 27/12 (20130101) Original (OR) Class H01L 29/0657 (20130101) H01L 2924/00 (20130101) H01L 2924/12041 (20130101) H01L 2924/13091 (20130101) H01L 2924/13091 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0283 (20130101) H05K 3/20 (20130101) H05K 2201/0133 (20130101) H05K 2201/09045 (20130101) H05K 2203/0271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324804 | Lagally et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Francesca Cavallo (Madison, Wisconsin); Richard Rojas-Delgado (Madison, Wisconsin) |
| ABSTRACT | Electrically conductive material structures, analog electronic devices incorporating the structures and methods for making the structures are provided. The structures include a layer of graphene on a semiconductor substrate. The graphene layer and the substrate are separated by an interfacial region that promotes transfer of charge carriers from the surface of the substrate to the graphene. |
| FILED | Friday, March 21, 2014 |
| APPL NO | 14/222163 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/185 (20130101) H01L 29/161 (20130101) H01L 29/1606 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324898 | Albin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); First Solar, Inc. (Toledo, Ohio) |
| ASSIGNEE(S) | Alliance For Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | David S. Albin (Denver, Colorado); James Neil Johnson (Scotia, New York); Yu Zhao (Niskayuna, New York); Bastiaan Arie Korevaar (Schenectady, New York) |
| ABSTRACT | A method for forming thin films or layers of cadmium telluride (CdTe) for use in photovoltaic modules or solar cells. The method includes varying the substrate temperature during the growth of the CdTe layer by preheating a substrate (e.g., a substrate with a cadmium sulfide (CdS) heterojunction or layer) suspended over a CdTe source to remove moisture to a relatively low preheat temperature. Then, the method includes directly heating only the CdTe source, which in turn indirectly heats the substrate upon which the CdTe is deposited. The method improves the resulting CdTe solar cell reliability. The resulting microstructure exhibits a distinct grain size distribution such that the initial region is composed of smaller grains than the bulk region portion of the deposited CdTe. Resulting devices exhibit a behavior suggesting a more n-like CdTe material near the CdS heterojunction than devices grown with substrate temperatures held constant during CdTe deposition. |
| FILED | Wednesday, September 25, 2013 |
| APPL NO | 14/036229 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02422 (20130101) H01L 21/02474 (20130101) H01L 21/02483 (20130101) H01L 21/02502 (20130101) H01L 21/02562 (20130101) H01L 31/073 (20130101) Original (OR) Class H01L 31/0296 (20130101) H01L 31/0368 (20130101) H01L 31/1836 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/543 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/521 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324985 | Wong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Wong (Hsinchu, Taiwan); Nitash Pervez Balsara (El Cerrito, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David Wong (Hsinchu, Taiwan); Nitash Pervez Balsara (El Cerrito, California) |
| ABSTRACT | The invention herein described is the use of a block copolymer/homopolymer blend for creating nanoporous materials for transport applications. Specifically, this is demonstrated by using the block copolymer poly(styrene-block-ethylene-block-styrene) (SES) and blending it with homopolymer polystyrene (PS). After blending the polymers, a film is cast, and the film is submerged in tetrahydrofuran, which removes the PS. This creates a nanoporous polymer film, whereby the holes are lined with PS. Control of morphology of the system is achieved by manipulating the amount of PS added and the relative size of the PS added. The porous nature of these films was demonstrated by measuring the ionic conductivity in a traditional battery electrolyte, 1M LiPF6 in EC/DEC (1:1 v/v) using AC impedance spectroscopy and comparing these results to commercially available battery separators. |
| FILED | Thursday, March 22, 2012 |
| APPL NO | 14/006576 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/145 (20130101) Original (OR) Class H01M 2/1653 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324992 | Gennett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas Gennett (Denver, Colorado); David S. Ginley (Evergreen, Colorado); Wade Braunecker (Boulder, Colorado); Chunmei Ban (Littleton, Colorado); Zbyslaw Owczarczyk (Littleton, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Thomas Gennett (Denver, Colorado); David S. Ginley (Evergreen, Colorado); Wade Braunecker (Boulder, Colorado); Chunmei Ban (Littleton, Colorado); Zbyslaw Owczarczyk (Littleton, Colorado) |
| ABSTRACT | Hybrid radical energy storage devices, such as batteries or electrochemical devices, and methods of use and making are disclosed. Also described herein are electrodes and electrolytes useful in energy storage devices, for example, radical polymer cathode materials and electrolytes for use in organic radical batteries. |
| FILED | Friday, September 12, 2014 |
| APPL NO | 14/484420 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) Original (OR) Class H01M 4/60 (20130101) H01M 4/64 (20130101) H01M 4/66 (20130101) H01M 4/0416 (20130101) H01M 4/602 (20130101) H01M 4/661 (20130101) H01M 4/1399 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 10/0565 (20130101) H01M 2220/20 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/54 (20151101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/81 (20130101) Y10S 977/734 (20130101) Y10S 977/742 (20130101) Y10S 977/773 (20130101) Y10S 977/811 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325030 | Zidan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ragaiy Zidan (Aiken, South Carolina) |
| ASSIGNEE(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Ragaiy Zidan (Aiken, South Carolina) |
| ABSTRACT | A battery and process of operating a battery system is provided using high hydrogen capacity complex hydrides in an organic non-aqueous solvent that allows the transport of hydride ions such as AlH4− and metal ions during respective discharging and charging steps. |
| FILED | Friday, September 28, 2012 |
| APPL NO | 13/629753 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/382 (20130101) H01M 10/26 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 2300/0037 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325145 | Neil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| ASSIGNEE(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| INVENTOR(S) | George Neil (Williamsburg, Virginia); Michelle D. Shinn (Newport News, Virginia); Joseph Gubeli (Gloucester, Virginia) |
| ABSTRACT | A method for improving the output beam quality of a free electron laser (FEL) by reducing the amount of emission at wavelengths longer than the electron pulse length and reducing the amount of edge radiation. A mirror constructed of thermally conductive material and having an aperture therein is placed at an oblique angle with respect to the beam downstream of the bending magnet but before any sensitive use of the FEL beam. The aperture in the mirror is sized to deflect emission longer than the wavelength of the FEL output while having a minor impact on the FEL output beam. A properly sized aperture will enable the FEL radiation, which is coherent and generally at a much shorter wavelength than the bending radiations, to pass through the aperture mirror. The much higher divergence bending radiations will subsequently strike the aperture mirror and be reflected safely out of the way. |
| FILED | Monday, May 11, 2015 |
| APPL NO | 14/708551 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0805 (20130101) H01S 3/0903 (20130101) Original (OR) Class H01S 3/08068 (20130101) H01S 5/0286 (20130101) H01S 5/18375 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325171 | Divan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Deepakraj M. Divan (San Jose, California); Anish Prasai (San Jose, California); Jorge Hernendez (Smyrna, Georgia); Rohit Moghe (Atlanta, Georgia); Amrit Iyer (Atlanta, Georgia); Rajendra Prasad Kandula (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION GEORGIA INSTITUTE OF TECHNOLOGY (Atlanta, Georgia) |
| INVENTOR(S) | Deepakraj M. Divan (San Jose, California); Anish Prasai (San Jose, California); Jorge Hernendez (Smyrna, Georgia); Rohit Moghe (Atlanta, Georgia); Amrit Iyer (Atlanta, Georgia); Rajendra Prasad Kandula (Atlanta, Georgia) |
| ABSTRACT | Power flow controllers based on Imputed DC Link (IDCL) cells are provided. The IDCL cell is a self-contained power electronic building block (PEBB). The IDCL cell may be stacked in series and parallel to achieve power flow control at higher voltage and current levels. Each IDCL cell may comprise a gate drive, a voltage sharing module, and a thermal management component in order to facilitate easy integration of the cell into a variety of applications. By providing direct AC conversion, the IDCL cell based AC/AC converters reduce device count, eliminate the use of electrolytic capacitors that have life and reliability issues, and improve system efficiency compared with similarly rated back-to-back inverter system. |
| FILED | Friday, February 01, 2013 |
| APPL NO | 13/757731 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) Original (OR) Class H02J 3/36 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/60 (20130101) Technical Subjects Covered by Former US Classification Y10T 307/50 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325335 | Milkov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California) |
| ASSIGNEE(S) | TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California) |
| INVENTOR(S) | Mihail M. Milkov (Moorpark, California) |
| ABSTRACT | A comparator circuit suitable for use in a column-parallel single-slope analog-to-digital converter comprises a comparator, an input voltage sampling switch, a sampling capacitor arranged to store a voltage which varies with an input voltage when the sampling switch is closed, and a local ramp buffer arranged to buffer a global voltage ramp applied at an input. The comparator circuit is arranged such that its output toggles when the buffered global voltage ramp exceeds the stored voltage. Both DC- and AC-coupled comparator embodiments are disclosed. |
| FILED | Friday, October 24, 2014 |
| APPL NO | 14/523179 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 3/0233 (20130101) H03K 4/90 (20130101) Coding; Decoding; Code Conversion in General H03M 1/002 (20130101) Original (OR) Class H03M 1/368 (20130101) H03M 1/0607 (20130101) H03M 1/1245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09326429 | Chainer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Timothy J. Chainer (Putnam Valley, New York); Pritish R. Parida (Fishkill, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); Pritish R. Parida (Fishkill, New York) |
| ABSTRACT | Cooling apparatuses are provided to facilitate active control of thermal and fluid dynamic performance of a coolant-cooled cold plate. The cooling apparatus includes the cold plate and a controller. The cold plate couples to one or more electronic components to be cooled, and includes an adjustable physical configuration. The controller dynamically varies the adjustable physical configuration of the cold plate based on a monitored variable associated with the cold plate or the electronic component(s) being cooled by the cold plate. By dynamically varying the physical configuration, the thermal and fluid dynamic performance of the cold plate are adjusted to, for example, optimally cool the electronic component(s), and at the same time, reduce cooling power consumption used in cooling the electronic component(s). The physical configuration can be adjusted by providing one or more adjustable plates within the cold plate, the positioning of which may be adjusted based on the monitored variable. |
| FILED | Thursday, September 06, 2012 |
| APPL NO | 13/604850 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20772 (20130101) Original (OR) Class H05K 7/20836 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 09320428 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Russell H. Taylor (Severna Park, Maryland); Seth D. Billings (Pellston, Maryland); Peter L. Gehlbach (Hunt Valley, Maryland); Gregory D. Hager (Baltimore, Maryland); James T. Handa (Baltimore, Maryland); Jin Ung Kang (Ellicott City, Maryland); Balazs Vagvolgyi (Baltimore, Maryland); Raphael Sznitman (Baltimore, Maryland); Zachary Pezzementi (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Russell H. Taylor (Severna Park, Maryland); Seth D. Billings (Pellston, Maryland); Peter L. Gehlbach (Hunt Valley, Maryland); Gregory D. Hager (Baltimore, Maryland); James T. Handa (Baltimore, Maryland); Jin Ung Kang (Ellicott City, Maryland); Balazs Vagvolgyi (Baltimore, Maryland); Raphael Sznitman (Baltimore, Maryland); Zachary Pezzementi (Baltimore, Maryland) |
| ABSTRACT | An observation system for viewing light-sensitive tissue includes an illumination system configured to illuminate the light-sensitive tissue, an imaging system configured to image at least a portion of the light-sensitive tissue upon being illuminated by the illumination system, and an image display system in communication with the imaging system to display an image of the portion of the light-sensitive tissue. The illumination system is configured to illuminate the light-sensitive tissue with a reduced amount of light within a preselected wavelength range compared to multispectral illumination light, and the image of the portion of the light-sensitive tissue is compensated for the reduced amount of light within the preselected frequency range to approximate an image of the light-sensitive tissue under the multispectral illumination. |
| FILED | Thursday, August 05, 2010 |
| APPL NO | 13/387950 |
| ART UNIT | 3737 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/13 (20130101) Original (OR) Class A61B 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320713 | Zhao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Yan Zhao (Ames, Iowa) |
| ABSTRACT | The invention provides multivalent surface-crosslinked micelle (SCM) particles, crosslinked reverse micelle (CRM) particles, and methods of making and using them. The SCM particles can be used, for example, to inhibit a virus or bacteria from binding to a host cell. The inhibition can be used in therapy for the flu, cancer, or AIDS. The CRM particles can be used, for example, to prepare metal nanoparticles or metal alloy nanoparticles, or they can be used in catalytic reactions. |
| FILED | Thursday, June 26, 2014 |
| APPL NO | 14/316585 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/107 (20130101) Original (OR) Class A61K 9/127 (20130101) A61K 9/1075 (20130101) A61K 9/1272 (20130101) A61K 47/20 (20130101) A61K 47/22 (20130101) A61K 47/24 (20130101) A61K 47/26 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0285 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2984 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320750 | Yaffe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael B. Yaffe (Somerville, Massachusetts); Michael Jungho Lee (Cambridge, Massachusetts); Paula T. Hammond (Newton, Massachusetts); Stephen W. Morton (Somerville, Massachusetts) |
| ABSTRACT | Time-staggered inhibition of EGFR, in combination with DNA damaging agents, is a useful therapeutic strategy for treating cancers, particularly drug resistant cancers such as a subset of triple-negative tumors, particularly those with high basal levels of phosphorylated EGFR. The staggered therapy was also demonstrated to be applicable to other types of tumors, especially lung cancers, which contain either high levels of phosphorylated wild-type EGFR or mutations within EGFR itself. EGFR inhibition dramatically sensitizes cancer cells to DNA damage if the drugs are given sequentially, but not simultaneously. The first drug must be administered in a dosage and for a period of time sufficient for the dynamic network rewiring of an oncogenic signature maintained by active EGFR signaling to unmask an apoptotic process that involves activation of caspase-8. |
| FILED | Tuesday, April 23, 2013 |
| APPL NO | 13/869012 |
| ART UNIT | 1673 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/704 (20130101) Original (OR) Class A61K 31/704 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320826 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bruce P. Lee (Madison, Wisconsin); Jeffrey L. Dalsin (Verona, Wisconsin); John L. Murphy (Verona, Wisconsin); Laura Vollenweider (Lodi, Wisconsin); Arinne N. Lyman (Fitchburg, Wisconsin); Fangmin Xu (Sudbury, Massachusetts); Jediah White (Madison, Wisconsin); William D. Lew (Mendota Heights, Minnesota); Michael Brodie (Belleville, Wisconsin) |
| ASSIGNEE(S) | KENSEY NASH CORPORATION (Exton, Pennsylvania) |
| INVENTOR(S) | Bruce P. Lee (Madison, Wisconsin); Jeffrey L. Dalsin (Verona, Wisconsin); John L. Murphy (Verona, Wisconsin); Laura Vollenweider (Lodi, Wisconsin); Arinne N. Lyman (Fitchburg, Wisconsin); Fangmin Xu (Sudbury, Massachusetts); Jediah White (Madison, Wisconsin); William D. Lew (Mendota Heights, Minnesota); Michael Brodie (Belleville, Wisconsin) |
| ABSTRACT | The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins. |
| FILED | Wednesday, November 09, 2011 |
| APPL NO | 13/292527 |
| ART UNIT | 3773 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/001 (20130101) A61L 24/0005 (20130101) A61L 24/046 (20130101) Original (OR) Class A61L 24/046 (20130101) A61L 24/046 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320827 | Zawko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Scott Zawko (Austin, Texas); Christine Schmidt (Gainesville, Florida) |
| ABSTRACT | The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel. |
| FILED | Wednesday, May 14, 2014 |
| APPL NO | 14/277170 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/0023 (20130101) A61L 26/0095 (20130101) Original (OR) Class A61L 27/26 (20130101) A61L 27/56 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0065 (20130101) Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) C08B 37/0015 (20130101) C08B 37/0045 (20130101) C08B 37/0072 (20130101) C08B 37/0075 (20130101) C08B 37/0084 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/26 (20130101) C08J 3/28 (20130101) C08J 3/075 (20130101) C08J 3/242 (20130101) C08J 2305/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0083 (20130101) Compositions of Macromolecular Compounds C08L 5/00 (20130101) C08L 5/00 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/06 (20130101) C08L 5/06 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 5/10 (20130101) C08L 5/10 (20130101) C08L 5/16 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321021 | Wong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael S. Wong (Houston, Texas); Hitesh Ghanshyam Bagaria (Houston, Texas); Gautam Chandrakanth Kini (Houston, Texas); Wen Yin Lynn Ko (Taichung, Taiwan) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Michael S. Wong (Houston, Texas); Hitesh Ghanshyam Bagaria (Houston, Texas); Gautam Chandrakanth Kini (Houston, Texas); Wen Yin Lynn Ko (Taichung, Taiwan) |
| ABSTRACT | An improved process for converting an oil suspension of nanoparticles (NPs) into a water suspension of NPs, wherein water and surfactant and a non-surfactant salt is used instead of merely water and surfactant, leading to greatly improved NP aqueous suspensions. |
| FILED | Thursday, July 30, 2009 |
| APPL NO | 13/056858 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 17/0085 (20130101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0008 (20130101) B01J 13/0039 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321030 | Sukhishvili et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | The Trustees of the Stevens Institute of Technology (Hoboken, New Jersey) |
| INVENTOR(S) | Svetlana Sukhishvili (Maplewood, New Jersey); Svetlana Pavlukhina (Bayonne, New Jersey) |
| ABSTRACT | A film for the retention and controlled release of organic or inorganic molecules consists essentially of a phyllosilicate clay and a organic polyanion. The film may be a built-up layered film of alternating layers of the clay and the polyanion. Organic or inorganic molecules are absorbed into the film from solution, and released in response to changes in the film's environment. The film may be built up using layer-by-layer (LbL) methods, or deposited on a substrate from a mixture of the clay and polyanion. Articles may be coated with the film by the same methods. The film is useful for the controlled release of antibiotics in response to infections, and also retains antibiotics such that bacteria may be killed by direct contact with the film. |
| FILED | Tuesday, December 18, 2012 |
| APPL NO | 14/370541 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/10 (20130101) Original (OR) Class B01J 20/3236 (20130101) B01J 20/3289 (20130101) B01J 20/28035 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/34 (20130101) C08K 9/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321675 | Jain |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Himanshu Jain (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Lehigh University (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Himanshu Jain (Bethlehem, Pennsylvania) |
| ABSTRACT | Provided herein are biocompatible scaffolds and methods of preparing such bioscaffolds. The methods provide a superior high surface area, interconnected nanomacroporous bioactive glass scaffold, by combining a sol-gel process and polymer sponge replication methods. The formation of a uniformly nanoporous and interconnected macroporous bioscaffold is demonstrated using a starting material comprising a 70 mol % SiO2—30 mol % CaO glass composition as an example. The bioscaffold includes a series of open, interconnected macropores with size from 300 to 600 μm, as desired for tissue ingrowth and vascularization. At the same time, coexisting nanopores provide high-specific surface area (>150 m2/g), which is needed for enhancing the structure's degradation rate. These bioscaffolds hold promise for applications in hard tissue engineering. |
| FILED | Friday, September 14, 2012 |
| APPL NO | 13/617293 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 19/06 (20130101) C03B 19/12 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 1/006 (20130101) C03C 3/078 (20130101) C03C 4/0007 (20130101) C03C 11/00 (20130101) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/622 (20130101) C04B 35/622 (20130101) C04B 38/0054 (20130101) C04B 38/0625 (20130101) C04B 38/0625 (20130101) C04B 2111/00836 (20130101) C04B 2235/36 (20130101) C04B 2235/616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321817 | Ficht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Allison Ficht (College Station, Texas); Theresa Good (Pasadena, Maryland); Kenneth Carson (San Antonio, Texas); Sungmun Lee (Seoul, South Korea) |
| ABSTRACT | The present inventions are compositions and methods of using at least a portion of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis. |
| FILED | Monday, April 14, 2014 |
| APPL NO | 14/251709 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322001 | Farinas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Edgardo Farinas (Pasadena, California); Frances H. Arnold (La Canada, California); Ulrich Schwaneberg (Ritterhude, Germany); Anton Glieder (Gieiadorf, Austria) |
| ABSTRACT | Nucleic acids encoding cytochrome P450 variants are provided. The cytochrome P450 variants of have a higher alkane-oxidation capability, alkene-oxidation capability, and/or a higher organic-solvent resistance than the corresponding wild-type or parent cytochrome P450 enzyme. A preferred wild-type cytochrome P450 is cytochrome P450 BM-3. Preferred cytochrome P450 variants include those having an improved capability to hydroxylate alkanes and epoxidate alkenes comprising less than 8 carbons, and have amino acid substitutions corresponding to V78A, H236Q, and E252G of cytochrome P450 BM-3. Preferred cytochrome P450 variants also include those having an improved hydroxylation activity in solutions comprising co-solvents such as DMSO and THF, and have amino acid substitutions corresponding to T235A, R471A, E494K, and S1024E of cytochrome P450 BM-3. |
| FILED | Saturday, May 10, 2014 |
| APPL NO | 14/274709 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/02 (20130101) C12P 7/04 (20130101) C12P 7/16 (20130101) C12P 17/02 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322047 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Taehyun Park (Baton Rouge, Louisiana); Daniel Sang-Won Park (Baton Rouge, Louisiana); Sudheer D Rani (Baton Rouge, Louisiana); Michael C Murphy (Baton Rouge, Louisiana); Dimitris E Nikitopoulos (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Taehyun Park (Baton Rouge, Louisiana); Daniel Sang-Won Park (Baton Rouge, Louisiana); Sudheer D Rani (Baton Rouge, Louisiana); Michael C Murphy (Baton Rouge, Louisiana); Dimitris E Nikitopoulos (Baton Rouge, Louisiana) |
| ABSTRACT | A device and methods are provided for efficient and quick capture of target cells through a main microchannel having capture elements immobilized thereon and manipulating a velocity profile of a sample as it passes through the main microchannel. The cell capture device may have a main microchannel with a depth slightly larger than the diameter of the target cells and a plurality of side microchannels. The side microchannels may have a depth smaller than the diameter of the target cells. The device and methods may be used for early cancer detection. |
| FILED | Friday, October 19, 2012 |
| APPL NO | 13/656295 |
| ART UNIT | 1677 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2200/0668 (20130101) B01L 2300/0816 (20130101) B01L 2300/0858 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322121 | Dunne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (St. Paul, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Lucy E. Dunne (Minneapolis, Minnesota); Guido Gioberto (Minneapolis, Minnesota) |
| ABSTRACT | A stitched sensor including a plurality of threads stitched to a textile in a stitch geometry is described. The plurality of threads includes a conductive thread, and the stitch geometry is configured such that an electrical property of the stitched sensor changes based on at least one of stretching, relaxation, or bending of the textile. Methods for forming a stitched sensor are also described. |
| FILED | Friday, February 28, 2014 |
| APPL NO | 14/193892 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Sewing D05B 93/00 (20130101) D05B 97/12 (20130101) Original (OR) Class Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/18 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322995 | Erickson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David Erickson (Ithaca, New York); Michal Lipson (Ithaca, New York); Allen Yang (Santa Barbara, California); Brad Schmidt (Toronto, Canada); Sean Moore (Colden, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | David Erickson (Ithaca, New York); Michal Lipson (Ithaca, New York); Allen Yang (Santa Barbara, California); Brad Schmidt (Toronto, Canada); Sean Moore (Colden, New York) |
| ABSTRACT | An architecture for the handling and transport of nanoscopic matter in lab on a chip devices using optical forces. A slot waveguide is used to focus and harness optical energy to trap and transport nanoscale objects. The slot waveguide is a unique structure that has several advantageous features, such as high optical confinement, and enables nanoparticles to interact fully with a propagating optical mode. |
| FILED | Friday, September 11, 2009 |
| APPL NO | 13/062867 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) Original (OR) Class G02B 6/125 (20130101) G02B 6/12007 (20130101) G02B 2006/12061 (20130101) G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323284 | Foster et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mark Foster (Sparks Glencoe, Maryland); Alexander Gaeta (Ithaca, New York); David Geraghty (Menlo Park, California); Michal Lipson (Ithaca, New York); Reza Salem (Columbia, Maryland); Amy Foster (Sparks Glencoe, Maryland) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Mark Foster (Sparks Glencoe, Maryland); Alexander Gaeta (Ithaca, New York); David Geraghty (Menlo Park, California); Michal Lipson (Ithaca, New York); Reza Salem (Columbia, Maryland); Amy Foster (Sparks Glencoe, Maryland) |
| ABSTRACT | There is set forth in one embodiment an apparatus and method for imparting a phase shift to an input waveform for output of a converted waveform. In one embodiment, a phase shift can be provided by four wave mixing of an input waveform and a pump pulse. In one embodiment, there is set forth an apparatus and method for generating a high resolution time domain representation of an input waveform comprising: dispersing the input waveform to generate a dispersed input waveform; subjecting the dispersed input waveform to four wave mixing by combining the dispersed input waveform with a dispersed pump pulse to generate a converted waveform; and presenting the converted waveform to a detector unit. In one embodiment a detector unit can include a spectrometer (spectrum analyzer) for recording of the converted waveform and output of a record representing the input waveform. |
| FILED | Wednesday, October 14, 2009 |
| APPL NO | 13/124305 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/00 (20130101) G01J 11/00 (20130101) G01J 2009/0226 (20130101) Optical Elements, Systems, or Apparatus G02B 27/46 (20130101) Optical Computing Devices; G06E 3/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323498 | Kim |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nam Sung Kim (Middleton, Wisconsin) |
| ABSTRACT | A fixed point multiplier that can be used in mobile computer systems operating under limited power constraints provides a trade-off between computational accuracy and energy consumption that may be changed dynamically for energy conservation purposes. In one embodiment, the multiplier pre-stores multiplication shift coefficients to eliminate leading-one circuitry normally used in shift and accumulate multipliers. |
| FILED | Wednesday, March 13, 2013 |
| APPL NO | 13/800709 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/53 (20130101) G06F 7/49942 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323614 | Kim |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nam Sung Kim (Middleton, Wisconsin) |
| ABSTRACT | A memory structure is provided that controls the activation of error handling bits as a function of operating voltage. In this way, error correction can be used to offset errors when the memory structure is run at low voltage (and frequency). However, negative performance impacts for such error correction, such as additional access latencies, can be avoided when the memory structure is run at higher voltage (and frequency) and memory errors are less likely. In addition, increased latencies due to evaluating error handling bits may be hidden by reading digital data bits from the memory structures speculatively and assuming no errors. Also, certain portions of memory structures may have larger cells, and therefore larger areas, than other portions, which may provide not only higher reliability at low operating voltages, but also faster operation with reduced latency. |
| FILED | Wednesday, November 06, 2013 |
| APPL NO | 14/073336 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1076 (20130101) Original (OR) Class Static Stores G11C 5/147 (20130101) G11C 29/52 (20130101) G11C 2029/0409 (20130101) G11C 2029/0411 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324151 | Snavely et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Noah Snavely (Menlo Park, California); Daniel Huttenlocher (Trumansburg, New York); Yungpeng Li (Zurich, Switzerland) |
| ABSTRACT | System and methods for determining where a digital photograph was taken by estimating the camera pose with respect to a global scale three-dimensional database. Accurate location and orientation of the digital photograph is established through feature correspondence and geometry estimated from photograph collections. |
| FILED | Saturday, December 08, 2012 |
| APPL NO | 14/361547 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 17/30247 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00664 (20130101) Image Data Processing or Generation, in General G06T 7/0044 (20130101) Original (OR) Class G06T 7/0046 (20130101) G06T 2200/04 (20130101) G06T 2207/30244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324310 | McPherson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Andrew McPherson (London, United Kingdom); Youngmoo Kim (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andrew McPherson (London, United Kingdom); Youngmoo Kim (Philadelphia, Pennsylvania) |
| ABSTRACT | A musical keyboard touch sensor pad having a plurality of integrated sensors disposed in an array is disclosed. The plurality of integrated sensors represents a keyboard key. A processor is electronically coupled to the plurality of integrated sensors. The processor is programmed to receive signals from several of the plurality of integrated sensors and to generate a sound signal based on input from the several of the plurality of integrated sensors. The output is variable based on the number in the plurality and the location of the plurality in the array. An audio output device is electronically coupled to the processor to generate a sound based on the sound signal. A keyboard using a plurality of the sensor pads as well as a method of generating sounds from the keyboard are also disclosed. |
| FILED | Friday, July 06, 2012 |
| APPL NO | 14/118900 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electrophonic Musical Instruments G10H 1/02 (20130101) G10H 1/344 (20130101) G10H 7/06 (20130101) Original (OR) Class G10H 2220/221 (20130101) G10H 2220/275 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324473 | Lavrentovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oleg D. Lavrentovich (Kent, Ohio); Heung-Shik Park (Kent, Ohio) |
| ASSIGNEE(S) | KENT STATE UNIVERSITY (Kent, Ohio) |
| INVENTOR(S) | Oleg D. Lavrentovich (Kent, Ohio); Heung-Shik Park (Kent, Ohio) |
| ABSTRACT | A nanoparticle composition, a device including the nanoparticle composition, and a method thereof are provided. The composition comprises nanoparticles such as Gold nanorods (NR) and electrically charged self-assembled molecular aggregates such as disodium chromoglycate (DSCG) in a common solvent such as water. The nanoparticles are assembled as, for example, side-by-side and end-to-end assemblies of nanorods, through a non-covalent interaction such as anisotropic electrostatic interaction with the electrically charged self-assembled molecular aggregates. The invention can be used in a cloaking device, a biological sensing device, a drug delivery, a meta material, a negative index material, an enhanced imaging device, and a device for solar energy conversion, and exhibits many merits such as simpler process without the need of a covalent bonding between the nanoparticles, different manners of nanoparticles assembling with same linker, higher thermal stability, cost effectiveness, and capability of gradual controlling of the degree of NR assembly, among others. |
| FILED | Tuesday, August 25, 2009 |
| APPL NO | 12/547062 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0022 (20130101) B22F 1/0025 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325240 | Calhoun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Benton H. Calhoun (Charlottesville, Virginia); Aatmesh Shrivastava (Charlottesville, Virginia) |
| ABSTRACT | The low input voltage boost converter with peak inductor current control and offset compensated zero detection provide a boost converter scheme to harvest energy from sources with small output voltages. Some embodiments described herein includes a thermoelectric boost converter that combines an IPEAK control scheme with offset compensation and duty cycled comparators to enable energy harvesting from TEG inputs as low as 5 mV to 10 mV, and the peak inductor current is independent to first order of the input voltage and output voltage. A control circuit can be configured to sample the input voltage (VIN) and then generate a pulse with a duration inversely proportional to VIN so as to control the boost converter switches such that a substantially constant peak inductor current is generated. |
| FILED | Tuesday, January 20, 2015 |
| APPL NO | 14/600425 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/462 (20130101) G05F 1/565 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/158 (20130101) Original (OR) Class H02M 2001/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 09322084 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xiaochun Li (Manhattan Beach, California); Noe Gaudencio Alba-Baena (El Paso, Texas); Daniel Earl Hoefert (Manitowoc, Wisconsin); David Weiss (Manitowoc, Wisconsin); Woo-hyun Cho (Seongnam-si, South Korea); Ben Peter Slater (Peoria, Illinois); Hongseok Choi (Clemson, South Carolina) |
| ABSTRACT | Apparatus and methods for industrial-scale production of metal matrix nanocomposites (MMNCs) are provided. The apparatus and methods can be used for the batch production of an MMNC in a volume of molten metal housed within the cavity of a production chamber. Within the volume of molten metal, a flow is created which continuously carries agglomerates of nanoparticles, which have been introduced into the molten metal, through a cavitation zone formed in a cavitation cell housed within the production chamber. |
| FILED | Tuesday, September 16, 2014 |
| APPL NO | 14/488019 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/1221 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 9/00 (20130101) C22B 9/103 (20130101) Alloys C22C 1/02 (20130101) Original (OR) Class C22C 1/1068 (20130101) C22C 32/0047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09323143 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frank Y. Xu (Round Rock, Texas); Weijun Liu (Cedar Park, Texas) |
| ASSIGNEE(S) | Canon Nanotechnologies, Inc. (Austin, Texas); Molecular Imprints, Inc. (Austin, Texas) |
| INVENTOR(S) | Frank Y. Xu (Round Rock, Texas); Weijun Liu (Cedar Park, Texas) |
| ABSTRACT | A nano-imprint lithography process includes forming a multiplicity of hydroxyl groups on a surface of a substantially inorganic nano-imprint lithography template, heating the template, and reacting a pre-selected percentage of the hydroxyl groups on the surface of the template with a mono-functional, non-fluorinated compound to form a monolayer coating on the surface of the nano-imprint lithography template. The coated template may be contacted with a polymerizable composition disposed on a nano-imprint lithography substrate, and the polymerizable composition solidified to form a patterned layer. The coated template is separated from the patterned layer. |
| FILED | Tuesday, February 03, 2009 |
| APPL NO | 12/364979 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/24802 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324534 | Sharifi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Washington, District of Columbia) |
| INVENTOR(S) | Fred Sharifi (Poolesville, Maryland); Myung-Gyu Kang (Gaithersburg, Maryland); Henri Lezec (Bethesda, Maryland) |
| ABSTRACT | A cold cathode field emission electron source capable of emission at levels comparable to thermal sources is described. Emission in excess of 6 A/cm2 at 7.5 V/μm is demonstrated in a macroscopic emitter array. The emitter has a monolithic and rigid porous semiconductor nanostructure with uniformly distributed emission sites, and is fabricated through a room temperature process which allows for control of emission properties. These electron sources can be used in a wide range of applications, including microwave electronics and x-ray imaging for medicine and security. |
| FILED | Monday, October 20, 2014 |
| APPL NO | 14/518253 |
| ART UNIT | 2879 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) B82Y 99/00 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/02 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 1/304 (20130101) H01J 1/3044 (20130101) Original (OR) Class H01J 1/3046 (20130101) H01J 9/022 (20130101) H01J 9/025 (20130101) H01J 2201/3048 (20130101) H01J 2201/30484 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/814 (20130101) Y10S 977/888 (20130101) Y10S 977/939 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324535 | Eaton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark Eaton (Austin, Texas); Mitali More (Austin, Texas); Mike Olla (Austin, Texas) |
| ASSIGNEE(S) | Stellarray, Incorporaated (Austin, Texas) |
| INVENTOR(S) | Mark Eaton (Austin, Texas); Mitali More (Austin, Texas); Mike Olla (Austin, Texas) |
| ABSTRACT | The present disclosure describes a self-contained irradiator comprising at least one X-ray source inside a shielded enclosure, the one or more sources each operable to emit X-ray flux across an area substantially equal to the proximate facing surface area of material placed inside the enclosure to be irradiated. The irradiator may have multiple flat panel X-ray sources disposed, designed or operated so as to provide uniform flux to the material being irradiated. The advantages of the irradiator of the present disclosure include compactness, uniform flux doses, simplified thermal management, efficient shielding and safety, the ability to operate at high power levels for sustained periods and high throughput. |
| FILED | Friday, January 22, 2010 |
| APPL NO | 12/692472 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/082 (20130101) A61L 2202/14 (20130101) A61L 2202/22 (20130101) A61L 2202/23 (20130101) A61L 2202/24 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/025 (20130101) G21K 5/02 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 35/06 (20130101) H01J 35/08 (20130101) H01J 35/14 (20130101) H01J 35/16 (20130101) H01J 35/18 (20130101) H01J 35/065 (20130101) Original (OR) Class H01J 2235/18 (20130101) H01J 2235/068 (20130101) H01J 2235/081 (20130101) H01J 2235/086 (20130101) H01J 2235/087 (20130101) H01J 2235/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325729 | Jajodia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia); The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia) |
| ASSIGNEE(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia); The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia) |
| INVENTOR(S) | Sushil Jajodia (Oakton, Virginia); Lingyu Wang (Montreal, Canada); Steven Noel (Woodbridge, Virginia); Anoop Singhal (Germantown, Maryland) |
| ABSTRACT | Systems and methods for determining a safety level of a network vulnerable to attack from at least one origin to at least one target are described. Machines, components, and vulnerabilities in a network may be associated to one another. Degrees of similarity among the vulnerabilities may be determined and subsets of vulnerabilities may be grouped based on their determined degrees of similarity to one another. This data may be used to generate an attack graph describing exploitation of vulnerabilities and grouped vulnerabilities and defining vulnerability exploit condition relationships between at least one origin and at least one target. The attack graph may be analyzed using a k-zero day metric function to determine a safety level. |
| FILED | Monday, July 07, 2014 |
| APPL NO | 14/324966 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1433 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 09320280 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Aijun Zhang (Ellicott City, Maryland); Christina Harris (Silver Spring, Maryland); Tracy C. Leskey (Shepherdstown, West Virginia) |
| ABSTRACT | Compositions (feeding deterrent/repellent for Halyomorpha halys) containing at least two compounds selected from tridecane, E-2-decenal, isolongifolanone, isolongifolenone, and at least one isolongifolenone analog having the following formula: wherein R1 is hydrogen, an oxygen, a C1-10 alcohol, aldehyde, alkyl, ether, or esters of said alcohol with a C1-10 saturated or unsaturated, straight or branched acid and R2 is hydrogen, an oxygen, a C1-10 alcohol, aldehyde, alkyl, ether, or esters of said alcohol with a C1-10 saturated or unsaturated, straight or branched acid; optionally there is a double bond between carbons 5 and 6 and R2 is hydrogen; and optionally a carrier or carrier material. Also methods for deterring feeding/repelling Halyomorpha halys involving treating an object or area with a Halyomorpha halys deterring feeding/repelling effective amount of at least one compound selected from the above compounds. |
| FILED | Thursday, February 07, 2013 |
| APPL NO | 13/761320 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 27/00 (20130101) A01N 35/02 (20130101) A01N 45/02 (20130101) Original (OR) Class A01N 45/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09320283 | Widmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as repressented by The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Timothy L. Widmer (Frederick, Maryland); Gary J. Samuels (Deering, New Hampshire) |
| ABSTRACT | Despite efforts of eradication and sanitation, Phytophthora ramorum persists in the United States and has been a problem in commercial nurseries since 2001. Detection in a nursery immediately causes the nursery to be under quarantine until the P. ramorum can be proven to be eradicated. Treatment with the biological control agent Trichoderma asperellum showed promise in laboratory results to remediate P. ramorum-infested potting soil. Sixteen T. asperellum isolates were screened, found to have variable mycoparasitic activities, and further tested in natural field settings. Field plots having P. ramorum-infested soil were treated with T. asperellum, a chemical and two different commercial biological control products and compared to non-treated infested soil. After 8 weeks, P. ramorum populations were not detected in the soil treated with T. asperellum isolate 04-22 showing that T. asperellum isolate 04-22 could remediate soils infested with P. ramorum under natural field conditions. |
| FILED | Tuesday, August 20, 2013 |
| APPL NO | 13/971294 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/00 (20130101) A01N 63/04 (20130101) Original (OR) Class A01N 63/04 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/885 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09321806 | Lo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Martin Lo (Ashton, Maryland); Hong Fu (Fujian, China PRC) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Martin Lo (Ashton, Maryland); Hong Fu (Fujian, China PRC) |
| ABSTRACT | A novel method for processing soluble plant leaf proteins is described. While leaf proteins are considered potentially the most abundant source of protein in nature, the lack of efficient processing techniques for leaf proteins has limited their commercial use. The method described in this patent provides a means of extracting and purifying leaf proteins from plants which is suitable for leaf protein production on an industrial scale. |
| FILED | Thursday, May 15, 2008 |
| APPL NO | 12/451429 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 36/81 (20130101) Peptides C07K 1/30 (20130101) C07K 1/36 (20130101) Original (OR) Class C07K 1/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09322068 | Khatib |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hasan Khatib (Fitchburg, Wisconsin) |
| ABSTRACT | Single nucleotide polymorphic sites of the bovine HSP genes are associated with improved fertilization rate and/or improved embryo survival rate in cattle. Nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods based on these SNPs are disclosed. |
| FILED | Thursday, June 19, 2014 |
| APPL NO | 14/309868 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Veterinary Instruments, Implements, Tools, or Methods A61D 19/02 (20130101) A61D 19/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 1/6888 (20130101) Original (OR) Class C12Q 2600/124 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 09321057 | Hintz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher Hintz (Savannah, Georgia); Amber Wilkinson (Savannah, Georgia) |
| ASSIGNEE(S) | Savannah State University (Savannah, Georgia) |
| INVENTOR(S) | Christopher Hintz (Savannah, Georgia); Amber Wilkinson (Savannah, Georgia) |
| ABSTRACT | An apparatus may include a separator and/or a discharger. A separator may include a separator channel, an influent portion configured to allow the passage of a first fluid into a separator channel, an effluent portion disposed above an influent portion and/or a fluid-lift portion between an influent portion and an effluent portion. A discharger may be disposed below a fluid-lift portion and/or may include a portion external to a separator channel, which may include a downward angle relative to an effluent portion and/or may be configured to minimize the passage of a second fluid into a discharger as the second fluid buoyantly travels in a separator channel from an influent portion to an effluent portion. A second fluid may have a density that is less than the density of a first and/or may be configured to lift a first fluid to a fluid-lift portion. |
| FILED | Monday, November 21, 2011 |
| APPL NO | 13/300883 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 21/24 (20130101) B01D 21/0084 (20130101) B01D 21/245 (20130101) Flotation; Differential Sedimentation B03D 1/26 (20130101) B03D 1/245 (20130101) Original (OR) Class B03D 2203/003 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/24 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/02 (20130101) G21F 9/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09324507 | Brandon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Erik J. Brandon (Pasadena, California); William C. West (South Pasadena, California); Ratnakumar V. Bugga (Arcadia, California) |
| ABSTRACT | Systems and methods in accordance with embodiments of the invention implement high-temperature tolerant supercapacitors. In one embodiment, a high-temperature tolerant super capacitor includes a first electrode that is thermally stable between at least approximately 80° C. and approximately 300° C.; a second electrode that is thermally stable between at least approximately 80° C. and approximately 300° C.; an ionically conductive separator that is thermally stable between at least approximately 80° C. and 300° C.; an electrolyte that is thermally stable between approximately at least 80° C. and approximately 300° C.; where the first electrode and second electrode are separated by the separator such that the first electrode and second electrode are not in physical contact; and where each of the first electrode and second electrode is at least partially immersed in the electrolyte solution. |
| FILED | Tuesday, June 10, 2014 |
| APPL NO | 14/301273 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/18 (20130101) Original (OR) Class H01G 11/32 (20130101) H01G 11/38 (20130101) H01G 11/52 (20130101) H01G 11/62 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 09322987 | Doany et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Fuad Doany (Katonah, New York); Daniel M. Kuchta (Patterson, New York); Petar K. Pepeljugoski (Tarrytown, New York); Laurent Schares (Luxembourg, Luxembourg) |
| ABSTRACT | An optical connector includes a fiber element incorporating one or more optical fibers, the optical fiber including a plurality of cores, and an optical element including an array of optical waveguides arranged in one or more layers so as to match the geometry of the plurality of cores of the optical fiber. |
| FILED | Tuesday, August 27, 2013 |
| APPL NO | 14/011381 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/423 (20130101) G02B 6/425 (20130101) G02B 6/02042 (20130101) Original (OR) Class G02B 6/3652 (20130101) G02B 6/4214 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09325542 | Agrawal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GLOBALFOUNDRIES Inc. (Grand Cayman, Cayman Islands) |
| ASSIGNEE(S) | GlobalFoundries Inc. (Grand Cayman, Cayman Islands) |
| INVENTOR(S) | Ankur Agrawal (Yorktown Heights, New York); Timothy O. Dickson (Yorktown Heights, New York); Sergey Rylov (Yorktown Heights, New York) |
| ABSTRACT | A parallel receiver interface includes a plurality of parallel data receivers, each receiver receiving input data. A clock receiver is configured to receive a forwarded clock. A phase interpolator has an input coupled to the output of the clock receiver and has an output coupled to each of the parallel receivers. Parallel clock delay elements are within each of the parallel data receivers, each clock delay element configured to provide varying amounts of clock phase adjustment. Inputs of a multiplexer circuit within each of the parallel data receivers are coupled to the outputs of each of the parallel clock delay elements within a respective parallel data receiver. An output of the multiplexer circuit is coupled to a data sampler within the respective parallel data receiver, the multiplexer circuit being configured to be controlled by a logic signal. |
| FILED | Wednesday, November 21, 2012 |
| APPL NO | 13/683508 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0008 (20130101) H04L 7/0025 (20130101) H04L 25/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 09322142 | Bergendahl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bart S. Bergendahl (Litteton, Colorado); Kornel Kerenyi (Oakton, Virginia) |
| ASSIGNEE(S) | The U.S. Department of Transportation, Federal Highway Administration (Washington, District of Columbia) |
| INVENTOR(S) | Bart S. Bergendahl (Litteton, Colorado); Kornel Kerenyi (Oakton, Virginia) |
| ABSTRACT | A field testing device usable to determine the scour-depth potential of soils relied upon to support structural foundations placed in flowing water is disclosed. The device measures the scour potential in-situ, in relative terms, to the scour potential of fine sand using a columnar containment vessel driven into the soil to be tested. Within the columnar containment vessel is a cutting head as an aid in directing a water flow in a generally horizontal direction across the surface of the soil to be tested. Additionally, the cutting head serves to aid in the evacuation of eroded soil from with the containment vessel through an exhaust port. The exhaust port is part of a continuous closed loop water system which provides water for the scour testing and then removes the used water along with eroded soil particulates. |
| FILED | Monday, August 05, 2013 |
| APPL NO | 13/958787 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 1/022 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 09320907 | Bogie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government, as represented by the Department of Veterans Affairs (Washington, District of Columbia); Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kath M. Bogie (Shaker Heights, Ohio); Steven L. Garverick (Cleveland Heights, Ohio); Christian A. Zorman (Euclid, Ohio); Daniel S. Howe (San Diego, California) |
| ABSTRACT | The present invention provides a thin and flexible device and method of use thereof for pain and wound treatment of a subject. The integrated surface stimulation device may comprise a complete wireless stimulation system in a disposable and/or reusable flexible device for widespread use in multiple therapeutic applications. The invention would be situated on the skin surface of a patient and would be activated so as to reduce the overall occurrence of pain and/or increase wound healing rates. As provided, the device will comprise an integrated power supply and pre-programmable stimulator/control system mounted on the upper face of a flexible polymeric substrate layer. The lower face of the substrate layer will comprise areas of stimulating electrodes, applied using thin film coating techniques. The device can then be applied to the user with a medical grade pressure sensitive adhesive coating provided on the lower face of the substrate layer. |
| FILED | Friday, January 18, 2013 |
| APPL NO | 14/363277 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/326 (20130101) A61N 1/0468 (20130101) A61N 1/0492 (20130101) A61N 1/36021 (20130101) A61N 1/37211 (20130101) A61N 1/37217 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 09323499 | Hyde et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elwha LLC, a limited liability corporation of the State of Delaware (Bellevue, Washington) |
| ASSIGNEE(S) | Elwha LLC (Bellevue, Washington) |
| INVENTOR(S) | Roderick A. Hyde (Redmond, Washington); Nicholas F. Pasch (Bellevue, Washington); Clarence T. Tegreene (Mercer Island, Washington) |
| ABSTRACT | A memory device includes but is not limited to a substrate, a non-volatile memory array integrated on the substrate, and random number generator logic integrated with the non-volatile memory array on the substrate. The random number generator logic is operable to perform at least one random number generator function in association with the non-volatile memory array. In addition to the foregoing, other aspects are described in the claims, drawings, and text forming a part of the present disclosure. |
| FILED | Friday, December 21, 2012 |
| APPL NO | 13/725788 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 09324900 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California) |
| ASSIGNEE(S) | TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California) |
| INVENTOR(S) | Allan Evans (Woodland Hills, California); William Tennant (Thousand Oaks, California); Andrew Hood (Ventura, California) |
| ABSTRACT | A method of fabricating a superlattice structure requires that atoms of a first III-V semiconductor compound be introduced into a vacuum chamber such that the atoms are deposited uniformly on a substrate. Atoms of at least one additional III-V compound are also introduced such that the atoms of the two III-V compounds form a repeating superlattice structure of alternating thin layers. Atoms of a surfactant are also introduced into the vacuum chamber while the III-V semiconductor compounds are being introduced, or immediately thereafter, such that the surfactant atoms act to improve the quality of the resulting SL structure. The surfactant is preferably bismuth, and the III-V semiconductor compounds are preferably GaSb along with either InAs or InAsSb; atoms of each material are preferably introduced using molecular beam epitaxy. The resulting superlattice structure is suitably used to form at least a portion of an IR photodetector. |
| FILED | Thursday, August 01, 2013 |
| APPL NO | 13/957266 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02463 (20130101) H01L 21/02466 (20130101) H01L 21/02507 (20130101) H01L 21/02546 (20130101) H01L 21/02549 (20130101) H01L 31/1844 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
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THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 26, 2016.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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FUNDED BY
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APPLICANT(S) and ASSIGNEES
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Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
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ABSTRACT
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FILED
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APPL NO
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
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CURRENT CPC
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The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
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