FedInvent™ Patents

Patent Details for Tuesday, July 05, 2016

This page was updated on Monday, March 27, 2023 at 04:49 AM GMT

Department of Health and Human Services (HHS)

09380769 — Transgenic chicken comprising an inactivated immunoglobulin gene

US 09380769	Leighton et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Phil Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California)
ASSIGNEE(S)	Crystal Bioscience Inc. (Emeryville, California)
INVENTOR(S)	Phil Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California)
ABSTRACT	A transgenic chicken comprising an inactivated heavy immunoglobulin gene and/or inactivated light chain immunoglobulin gene is provided, as well as cells and targeting vectors for making the same.
FILED	Wednesday, May 23, 2012
APPL NO	14/114159
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Original (OR) Class A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/902 (20130101)
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09380784 — Antimicrobial compositions and methods of use

US 09380784	Derby et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)	Charles Derby (Decatur, Georgia); Binghe Wang (Marietta, Georgia); Phang C. Tai (Atlanta, Georgia); Ko-Chun Ko (Atlanta, Georgia); Michiya Kamio (Tokyo, Japan)
ASSIGNEE(S)
INVENTOR(S)	Charles Derby (Decatur, Georgia); Binghe Wang (Marietta, Georgia); Phang C. Tai (Atlanta, Georgia); Ko-Chun Ko (Atlanta, Georgia); Michiya Kamio (Tokyo, Japan)
ABSTRACT	Disclosed herein are antimicrobial compositions, kits, and articles of manufacture. Further disclosed herein are methods for treating surfaces, including tissue, inter alia, wounds, with the disclosed compositions.
FILED	Monday, July 27, 2009
APPL NO	13/055221
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/22 (20130101) A01N 31/02 (20130101) A01N 37/42 (20130101) A01N 37/44 (20130101) A01N 37/50 (20130101) A01N 59/00 (20130101) Original (OR) Class A01N 59/00 (20130101) A01N 59/00 (20130101) A01N 2300/00 (20130101)
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09380950 — Methods for detecting biological rhythm disorders

US 09380950	Narayan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF) Office of The Director (OD) Office of General Counsel(OGC)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFARIS, OFFICE OF GENERAL COUNSEL (Washington, District of Columbia)
INVENTOR(S)	Sanjiv Narayan (La Jolla, California); Wouter-Jan Rappel (San Diego, California)
ABSTRACT	A method of detecting a cause of a heart rhythm disorder includes collecting data corresponding to activation onset time of each heart activation at multiple locations of the heart and generating an activation trail based on the sequential order of activation onset times. The activation trail is indicative of the cause of the heart rhythm disorder.
FILED	Monday, August 12, 2013
APPL NO	13/964604
ART UNIT	3766 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/04 (20130101) A61B 5/044 (20130101) A61B 5/046 (20130101) A61B 5/0245 (20130101) A61B 5/0402 (20130101) A61B 5/0452 (20130101) A61B 5/0464 (20130101) A61B 5/726 (20130101) A61B 5/02405 (20130101) Original (OR) Class A61B 5/04011 (20130101) A61B 5/04012 (20130101) A61B 5/4836 (20130101) A61B 5/7203 (20130101) A61B 18/1206 (20130101) A61B 18/1492 (20130101) A61B 2018/00214 (20130101) A61B 2018/00357 (20130101) A61B 2018/00375 (20130101) A61B 2018/00839 (20130101) A61B 2018/1435 (20130101)
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09380967 — Systems and methods for measuring fetal cerebral oxygenation

US 09380967	Esenaliev et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD)
APPLICANT(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S)	THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S)	Rinat Esenaliev (League City, Texas); Donald S. Prough (Galveston, Texas); Yuriy Petrov (Galveston, Texas); Irene Petrov (Galveston, Texas); George Saade (Houston, Texas); Gayle L. Olson (Galveston, Texas)
ABSTRACT	Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.
FILED	Wednesday, July 08, 2015
APPL NO	14/793969
ART UNIT	3777 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0095 (20130101) A61B 5/742 (20130101) A61B 5/1459 (20130101) A61B 5/1464 (20130101) A61B 5/6814 (20130101) A61B 5/6875 (20130101) A61B 5/14542 (20130101) Original (OR) Class A61B 5/14553 (20130101) A61B 2562/0271 (20130101)
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09381110 — Method and system for training voice patterns

US 09381110	Huber et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)	PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S)	Jessica E. Huber (Lafayette, Indiana); Scott Kepner (West Lafayette, Indiana); Derek Tully (Indianapolis, Indiana); James Thomas Jones (Brookston, Indiana); Kirk Solon Foster (West Lafayette, Indiana)
ABSTRACT	One example embodiment of the present disclosure includes method and system to improve communication comprising an assembly fixedly positioned during use in close proximity to a user's ear. The assembly includes an accelerometer to detect the initiation and duration of the user's speech and an output presentation system. The output presentation system comprises a non-occlusive ear fitting that presents unintelligible noise that is unrelated to the sound-frequency or intonation of the user's current speech. The unintelligible noise is presented to the patient at a level less than 85 dB. The system further comprises a control arrangement to maintain presentation of the noise substantially throughout the detected duration of the user's speech, but substantially not at other times.
FILED	Wednesday, April 30, 2014
APPL NO	14/266289
ART UNIT	3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/58 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/04 (20130101) G09B 21/00 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 2021/0575 (20130101) G10L 2021/03646 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115)
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09381164 — Silk nanospheres and microspheres and methods of making same

US 09381164	Wang et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB) Tissue Engineering Resource Center (TERC)
APPLICANT(S)	TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts)
ASSIGNEE(S)	Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S)	Xiaoqin Wang (Winchester, Massachusetts); David L. Kaplan (Concord, Massachusetts)
ABSTRACT	The present invention provides for methods of preparing silk nanoparticles and microparticles, methods of encapsulating an active agent into the silk nano- and microparticles and compositions comprising these silk particles. In particular, the silk spheres are prepared from phase separation of silk and polyvinyl alcohol (PVA), without exposure to an organic solvent. The method employs a chemical, PVA, which is an FDA-approved ingredient in drug formulations. Different parameters can be adjusted to control the size and shape of the silk spheres during the fabrication process. The silk particle compositions of the present invention may also encapsulate active agents or chemicals. Such compositions allow the active agents to be controllably and sustainably released to the target organs or tissues. The silk composition entrapping active agents also provides for a long-term storage medium for the active agents so entrapped. The silk nano- and microparticles of the present invention are thus suitable for a variety of biomedical and pharmaceutical applications, such as drug delivery or tissue engineering.
FILED	Monday, March 17, 2014
APPL NO	14/216756
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/1605 (20130101) A61K 9/1647 (20130101) A61K 9/5052 (20130101) A61K 9/5089 (20130101) A61K 9/5169 (20130101) Original (OR) Class A61K 9/5192 (20130101) A61K 31/352 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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09381176 — E-prostanoid receptor, Ptger3, as a novel anti-diabetic therapeutic target

US 09381176	Keller et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Mark Keller (McFarland, Wisconsin); Alan Attie (Madison, Wisconsin); Michelle Kimple (Madison, Wisconsin)
ABSTRACT	Provided herein are methods for increasing insulin secretion from beta cells. Also provide herein are methods comprising administering to a subject in need of increased insulin secretion a composition comprising a compound that directly or indirectly activates adenylate cyclase and an E prostanoid 3 (EP3) receptor antagonist that attenuates G alpha-i-subfamily (GSIS)-mediated adenylate cyclase inhibition.
FILED	Friday, February 22, 2013
APPL NO	13/774516
ART UNIT	1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) Original (OR) Class A61K 31/18 (20130101) A61K 31/404 (20130101) A61K 31/404 (20130101) A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 38/26 (20130101) A61K 38/26 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09381185 — Methods of inducing sedation

US 09381185	Brosnan
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, Canada)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Robert J. Brosnan (Davis, California)
ABSTRACT	The present invention provides methods of inducing sedation in a subject by administering an effective amount of a compound or a mixture of compounds according to Formula I. Compounds of Formula I are a class of halogenated alcohol derivatives with a vapor pressure of less than 0.1 atmospheres (76 mmHg) at 25° C. The compounds of the present invention can be administered by any route sufficient to achieve a desired anesthetic, amnestic, analgesic, or sedative effect.
FILED	Wednesday, July 10, 2013
APPL NO	14/414089
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Veterinary Instruments, Implements, Tools, or Methods A61D 7/04 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/08 (20130101) A61K 31/025 (20130101) A61K 31/045 (20130101) A61K 31/341 (20130101) A61K 31/351 (20130101) Original (OR) Class A61K 31/357 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/01 (20130101)
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09381193 — Contraceptive methods and compositions

US 09381193	Moley et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	Kelle H. Moley (St. Louis, Missouri); Antonina I. Frolova (St. Louis, Missouri)
ASSIGNEE(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S)	Kelle H. Moley (St. Louis, Missouri); Antonina I. Frolova (St. Louis, Missouri)
ABSTRACT	The invention encompasses compositions and methods for use in preventing pregnancy.
FILED	Friday, March 30, 2012
APPL NO	13/436469
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/455 (20130101) Original (OR) Class A61K 31/5685 (20130101) A61K 31/7008 (20130101)
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09381203 — Combination therapies for treatment of laminopathies, cellular aging, and atherosclerosis

US 09381203	Gordon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Leslie B. Gordon (Foxboro, Massachusetts); Mark W. Kieran (Newton, Massachusetts); Monica E. Kleinman (Sharon, Massachusetts)
ASSIGNEE(S)
INVENTOR(S)	Leslie B. Gordon (Foxboro, Massachusetts); Mark W. Kieran (Newton, Massachusetts); Monica E. Kleinman (Sharon, Massachusetts)
ABSTRACT	Provided herein are combination therapies for the treatment of progeroid diseases and conditions, cellular aging, bone diseases, and cardiovascular diseases. The provided combination therapies target the aberrant farnesylation of the mutant lamin A protein progerin, and inhibit farnesyl biosynthesis, lamin A prenylation, and increase progerin clearance.
FILED	Thursday, March 13, 2014
APPL NO	14/209197
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) A61K 31/22 (20130101) A61K 31/55 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/663 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 31/675 (20130101) A61K 31/4545 (20130101) A61K 31/4545 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101)
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09381210 — Induced pluripotent stem cell model of chronic myeloid leukemia revealed olfactomedin 4 as a novel therapeutic target in leukemia stem cells

US 09381210	Slukvin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Igor I. Slukvin (Madison, Wisconsin); Kran Suknuntha (Madison, Wisconsin)
ABSTRACT	Disclosed herein are compositions and methods to treat and reduce therapeutic resistance in chronic myelogenous leukemia. Also disclosed herein are methods to generate leukemia stem cell like cells (iLSCs) generated from CML patient-derived iPSCs, and methods for utilizing iLSCs in screens to identify modulators of CML drug resistance and gene targets that underlie CML drug resistance.
FILED	Friday, April 11, 2014
APPL NO	14/251231
ART UNIT	1674 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 31/5025 (20130101) A61K 31/5025 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 5/0695 (20130101) C12N 2501/22 (20130101) C12N 2501/26 (20130101) C12N 2501/125 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2502/1358 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5044 (20130101) G01N 33/57426 (20130101) G01N 2333/9121 (20130101) G01N 2500/10 (20130101)
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09381226 — Methods and compositions related to inhibition of viral entry

US 09381226	Kay et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Michael S. Kay (Salt Lake City, Utah); Brett D. Welch (Salt Lake City, Utah)
ASSIGNEE(S)	UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S)	Michael S. Kay (Salt Lake City, Utah); Brett D. Welch (Salt Lake City, Utah)
ABSTRACT	Disclosed are compositions and methods for inhibiting viral entry.
FILED	Friday, February 08, 2008
APPL NO	12/526071
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) Original (OR) Class A61K 47/481 (20130101) A61K 47/48215 (20130101) A61K 47/48253 (20130101) Peptides C07K 5/1024 (20130101) C07K 7/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/56983 (20130101) G01N 2333/005 (20130101) G01N 2333/162 (20130101) G01N 2500/00 (20130101)
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09381227 — Treatment of ischemia

US 09381227	Simon et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	Morehouse School of Medicine (Atlanta, Georgia)
ASSIGNEE(S)	MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
INVENTOR(S)	Roger P. Simon (Portland, Oregon); Zhi-Gang Xiong (Beaverton, Oregon)
ABSTRACT	A system, including methods and compositions, for treatment of ischemia.
FILED	Tuesday, March 17, 2015
APPL NO	14/660581
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Original (OR) Class A61K 38/17 (20130101) A61K 38/1767 (20130101) Peptides C07K 14/43518 (20130101)
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09381231 — Use of relaxin to restore maternal physiology in pregnancies conceived by assisted reproductive technologies

US 09381231	Conrad
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Child Health and Human Development (NICHD) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
ASSIGNEE(S)	UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S)	Kirk P. Conrad (Gainesville, Florida)
ABSTRACT	The subject invention relates to methods for improving a subject's vasculature to normalize maternal hemodynamics, particularly in subjects attempting to conceive via assisted reproductive technologies, and comprises increasing relaxin levels in a subject or increasing any one or more of: relaxin synthesis, relaxin receptor synthesis, relaxin binding to the relaxin receptor, or relaxin receptor activity.
FILED	Wednesday, October 09, 2013
APPL NO	14/049620
ART UNIT	1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/2221 (20130101) Original (OR) Class A61K 38/2221 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101)
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09381235 — Programming of cells for tolerogenic therapies

US 09381235	Sands et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Forsyth Dental Infirmary for Children (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts); Forsyth Dental Infirmary for Children (Cambridge, Massachusetts)
INVENTOR(S)	Roger Warren Sands (Chicago, Illinois); Eduardo Alexandre Barros e Silva (Davis, California); Toshihisa Kawai (Brookline, Massachusetts); David J. Mooney (Sudbury, Massachusetts)
ABSTRACT	Biomaterial systems, e.g., gel scaffolds, are used in vivo to recruit immune cells and promote their activation towards a non-inflammatory phenotype, thereby leading suppression of inflammation. The compositions and methods are useful to reduce the severity of autoimmunity, chronic inflammation, allergy, and periodontal disease.
FILED	Thursday, February 20, 2014
APPL NO	14/185494
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/35 (20130101) A61K 39/39 (20130101) A61K 39/102 (20130101) A61K 2039/70 (20130101) A61K 2039/577 (20130101) A61K 2039/5158 (20130101) A61K 2039/55522 (20130101) A61K 2039/55561 (20130101)
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09381236 — Interferon-β production modulating listeria strains and methods for using same

US 09381236	Portnoy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Daniel A. Portnoy (Albany, California); Anat A. Herskovits (Morgan Hill, California); Gregory Crimmins (Berkeley, California)
ABSTRACT	Mutant Listeria bacteria that modulate interferon-β production are provided. The subject bacteria are characterized by having a mutation in a gene chosen from a TetR gene, a LadR gene, a VirR gene, a MarR gene a MdrL gene, a MdrT gene and a MdrM gene. The subject bacteria find use in a variety of applications, where representative applications of interest include, but are not limited to: (a) use of the subject bacteria as adjuvants; (b) use of the subject bacteria as delivery vectors for introducing macromolecules into a cell; (c) use of the subject bacteria as vaccines for eliciting or boosting a cellular immune response; etc.
FILED	Tuesday, June 16, 2015
APPL NO	14/741107
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/02 (20130101) Original (OR) Class A61K 39/0208 (20130101) A61K 2039/58 (20130101) A61K 2039/522 (20130101)
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09381260 — Hypoxia inducible factor-1 pathway inhibitors and uses as anticancer and imaging agents

US 09381260	Mun et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	EMORY UNIVERSITY (Atlanta, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia)
INVENTOR(S)	Jiyoung Mun (Atlanta, Georgia); Mark M. Goodman (Atlanta, Georgia); Erwin G. Van Meir (Tucker, Georgia)
ABSTRACT	This disclosure relates to Hypoxia Inducible Factor-1 pathway inhibitors and uses as anticancer and imaging agents. In certain embodiments, the disclosure contemplates compounds and pharmaceutical compositions disclosed herein.
FILED	Thursday, December 27, 2012
APPL NO	13/728821
ART UNIT	1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/352 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/4178 (20130101) A61K 31/4178 (20130101) A61K 31/4433 (20130101) A61K 31/4433 (20130101) A61K 45/06 (20130101) A61K 51/0421 (20130101) A61K 51/0453 (20130101) A61K 51/0455 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 311/58 (20130101) C07D 405/12 (20130101) C07D 417/12 (20130101)
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09381261 — SHK-based pharmaceutical compositions and methods of manufacturing and using the same

US 09381261	Iadonato et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)	Shawn P Iadonato (Seattle, Washington); Eric J Tarcha (Seattle, Washington)
ASSIGNEE(S)	Kineta One, LLC (Seattle, Washington)
INVENTOR(S)	Shawn P Iadonato (Seattle, Washington); Eric J Tarcha (Seattle, Washington)
ABSTRACT	Disclosed herein are pharmaceutical compositions having the sequence Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Lys-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Xaa-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys (SEQ ID NO: 1). The disclosed compositions can include an acid or amide at the C-terminus of SEQ ID NO: 1 and the polypeptide can be attached to an organic or inorganic chemical entity that has an anionic charge. The polypeptide can be detectably labeled for diagnostic purposes. Methods of manufacturing and using the pharmaceutical compounds are also disclosed.
FILED	Tuesday, June 05, 2012
APPL NO	14/124669
ART UNIT	1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 38/1767 (20130101) A61K 47/4803 (20130101) A61K 49/0002 (20130101) A61K 51/088 (20130101) Original (OR) Class Chemical or Physical Laboratory Apparatus for General Use B01L 3/12 (20130101) B01L 9/00 (20130101) B01L 99/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/43504 (20130101)
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09381276 — Electrochemical disinfection of implanted catheters

US 09381276	Joseph et al.
FUNDED BY	Department of Health and Human Services (HHS) Food and Drug Administration (FDA)
APPLICANT(S)	SRI INTERNATIONAL (Menlo Park, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	SRI INTERNATIONAL (Menlo Park, California); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Jose P. Joseph (Palo Alto, California); Pablo E. Garcia (Menlo Park, California); Karen F. Shakespear (Menlo Park, California); Sarah Young (Menlo Park, California); Janus A. J. Haagensen (Menlo Park, California); Sanjeev Dutta (Menlo Park, California)
ABSTRACT	An implantable catheter is provided that may be disinfected without removal from the body of a patient, using an electrochemical method to generate an electric field on the catheter surface and thus destroy microorganisms in a biofilm that is present or forming. A catheter system includes the implantable catheter and a voltage source that is operably connected to electrodes on or embedded in the exterior and optionally the interior catheter surface. Methods are also provided for disinfecting the implantable catheter in vivo and for detecting or confirming the presence of a pathogenic biofilm thereon.
FILED	Tuesday, March 15, 2016
APPL NO	15/070073
ART UNIT	1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/02 (20130101) A61L 29/06 (20130101) Original (OR) Class A61L 29/041 (20130101) A61L 29/126 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0045 (20130101) A61M 2025/0019 (20130101)
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09381282 — Tropoelastin for promoting endothelial cell adhesion or migration

US 09381282	Li et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
ASSIGNEE(S)	University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S)	Dean Y. Li (Salt Lake City, Utah); Brent D. Wilson (Salt Lake City, Utah); Lise Sorensen Brunhart (Salt Lake City, Utah)
ABSTRACT	The invention provides methods, compositions, and devices for promoting adhesion or migration of endothelial cell.
FILED	Wednesday, July 30, 2014
APPL NO	14/446973
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/39 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 27/3808 (20130101) A61L 27/3895 (20130101) A61L 29/16 (20130101) A61L 29/048 (20130101) A61L 29/085 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) Original (OR) Class A61L 31/047 (20130101) A61L 2300/42 (20130101) A61L 2300/61 (20130101) A61L 2300/416 (20130101) A61L 2400/18 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) C08L 89/00 (20130101) C08L 89/00 (20130101)
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09381477 — Microfluidic synthesis of organic nanoparticles

US 09381477	Karnik et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Rohit Karnik (Cambridge, Massachusetts); Frank X. Gu (Waterloo, Canada); Pamela Basto (Somerville, Massachusetts); Chris Cannizzaro (Washington, District of Columbia); Alireza Khademhosseini (Cambridge, Massachusetts); Robert S. Langer (Newton, Massachusetts); Omid C. Farokhzad (Chestnut Hill, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S)	Rohit Karnik (Cambridge, Massachusetts); Frank X. Gu (Waterloo, Canada); Pamela Basto (Somerville, Massachusetts); Chris Cannizzaro (Washington, District of Columbia); Alireza Khademhosseini (Cambridge, Massachusetts); Robert S. Langer (Newton, Massachusetts); Omid C. Farokhzad (Chestnut Hill, Massachusetts)
ABSTRACT	The present invention provides microfluidic systems and methods for the production of particles (e.g., nanoparticles) for drug delivery. The present invention provides microfluidic devices useful for production of particles by nanoprecipitation. The present invention provides highly homogenous compositions of particles produced by inventive microfluidic devices.
FILED	Friday, June 22, 2007
APPL NO	12/306249
ART UNIT	1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/1694 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/48907 (20130101) A61K 47/48915 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) Original (OR) Class B01F 5/061 (20130101) B01F 5/0471 (20130101) B01F 5/0646 (20130101) B01F 5/0647 (20130101) B01F 11/0071 (20130101) B01F 13/0059 (20130101) B01F 13/0062 (20130101) B01F 2005/0621 (20130101) B01F 2005/0636 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/04 (20130101) B01J 19/0046 (20130101) B01J 19/0093 (20130101) B01J 2219/005 (20130101) B01J 2219/0059 (20130101) B01J 2219/0095 (20130101) B01J 2219/00162 (20130101) B01J 2219/00164 (20130101) B01J 2219/00459 (20130101) B01J 2219/00722 (20130101) B01J 2219/00725 (20130101) B01J 2219/00736 (20130101) B01J 2219/00822 (20130101) B01J 2219/00828 (20130101) B01J 2219/00831 (20130101) B01J 2219/00833 (20130101) B01J 2219/00889 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101)
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09382193 — Processes for forming amide bonds and compositions related thereto

US 09382193	Liebeskind et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	EMORY UNIVERSITY (Atlanta, Georgia)
ASSIGNEE(S)	Emory University (Atlanta, Georgia)
INVENTOR(S)	Lanny S. Liebeskind (Atlanta, Georgia); Wenting Wu (Decatur, Georgia); Zhihui Zhang (New Berlin, Wisconsin); Hao Li (Decatur, Georgia); Angus A. Lamar (Atlanta, Georgia)
ABSTRACT	The disclosure relates to methods for producing amide bonds and reagents related thereto. In some embodiments, the disclosure relates to methods of producing an amide comprising mixing an O-silylated thionoester and an amine under conditions such that an amide is formed. In another embodiment, the disclosure relates to mixing a thiolacid, a silylating agent, and an amine under conditions such that an amide is formed.
FILED	Monday, December 29, 2014
APPL NO	14/583850
ART UNIT	1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 231/02 (20130101) Original (OR) Class C07C 233/07 (20130101) C07C 233/65 (20130101) C07C 233/69 (20130101) Heterocyclic Compounds C07D 213/82 (20130101) C07D 233/90 (20130101) C07D 295/192 (20130101) C07D 307/52 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/1852 (20130101) C07F 7/1856 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 21/02 (20130101) Peptides C07K 1/02 (20130101) C07K 1/003 (20130101) C07K 5/0606 (20130101) C07K 5/0812 (20130101) C07K 5/06026 (20130101) C07K 5/06034 (20130101) C07K 5/06078 (20130101) C07K 5/06086 (20130101) C07K 5/06104 (20130101)
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09382208 — Negative allosteric modulators of metabotropic glutamate receptor 2

US 09382208	Conn et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S)	Vanderbilt University (Nashville, Tennessee)
INVENTOR(S)	P. Jeffrey Conn (Nashville, Tennessee); Craig W. Lindsley (Brentwood, Tennessee); Kyle A. Emmitte (Spring Hill, Tennessee); Andrew S. Felts (Brentwood, Tennessee); Katrina A. Bollinger (Murfreesboro, Tennessee)
ABSTRACT	Described are negative allosteric modulators of metabotropic glutamate receptor 2 (mGlu₂), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating depression, anxiety, obsessive-compulsive disorder, cognitive disorders, Alzheimer's disease, or autism spectrum disorders in a subject.
FILED	Tuesday, January 26, 2016
APPL NO	15/006486
ART UNIT	1672 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Heterocyclic Compounds C07D 215/233 (20130101) Original (OR) Class C07D 401/06 (20130101) C07D 401/12 (20130101) C07D 413/06 (20130101) C07D 417/14 (20130101)
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09382213 — Heterocyclic and cyclic analogs of propargyl-linked inhibitors of dihydrofolate reductase

US 09382213	Wright et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Dennis L Wright (Storrs, Connecticut); Amy C Anderson (Storrs, Connecticut); Grant Sormunen (Athens, Ohio)
ASSIGNEE(S)	PROMILIAD BIOPHARMA INC. (Alberton, Montana); UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S)	Dennis L Wright (Storrs, Connecticut); Amy C Anderson (Storrs, Connecticut); Grant Sormunen (Athens, Ohio)
ABSTRACT	Compounds of Formula I and Formula IA are inhibitors of dihydrofolate reductase and are suitable for use in compositions and methods for dihydrofolate reductase inhibition or, more specifically, treatment of a fungal infection, a bacterial infection or a protozoal infection, and, in specific embodiments, treatment of a fungal infection caused by C. albicans or C. glabrata: wherein R, R₁, R₂, R₃, R₄, A, B, E, V, W, X, Y and Z are as defined herein.
FILED	Thursday, February 12, 2015
APPL NO	14/620997
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) Heterocyclic Compounds C07D 239/42 (20130101) C07D 239/48 (20130101) Original (OR) Class C07D 401/06 (20130101) C07D 401/14 (20130101) C07D 403/06 (20130101) C07D 405/14 (20130101) C07D 409/14 (20130101)
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09382215 — Therapeutic methods and agents for treating myotonic dystrophy

US 09382215	Zimmerman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S)	The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S)	Steven C. Zimmerman (Champaign, Illinois); Chun-Ho Wong (Champaign, Illinois); Paul J. Hergenrother (Champaign, Illinois); Jessie Peh (Urbana, Illinois)
ABSTRACT	The invention provides compounds, compositions and methods for treating myotonic dystrophy. The compounds can selectively bind to CUG repeats in RNA, or to CTG repeats in DNA, and inhibit replication of the nucleic acids.
FILED	Thursday, June 05, 2014
APPL NO	14/297037
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/008 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/2054 (20130101) A61K 9/4858 (20130101) Heterocyclic Compounds C07D 251/70 (20130101) Original (OR) Class
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09382217 — Modulators of sphingosine phosphate receptors

US 09382217	Roberts et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S)	The Scripps Research Institute (La Jolla, California)
INVENTOR(S)	Edward Roberts (Fallbrook, California); Hugh Rosen (La Jolla, California); Steven Brown (San Diego, California); Miguel A. Guerrero (San Diego, California); Xuemei Peng (La Jolla, California); Ramulu Poddutoori (La Jolla, California)
ABSTRACT	Compounds that activate a sphingosine-1-phosphate receptor of the subtype 1 are provided. Certain compounds selectively activate the receptor subtype 1 in relation to the sphinogosine-1-phosphate receptor subtype 3. Uses and methods of inventive compounds for treatment of malconditions wherein activation, agonism, inhibition or antagonism of the S1P1 is medically indicated are provided.
FILED	Monday, June 23, 2014
APPL NO	14/311825
ART UNIT	1626 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4245 (20130101) Heterocyclic Compounds C07D 263/32 (20130101) C07D 271/06 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 413/04 (20130101) C07D 413/14 (20130101) C07D 471/04 (20130101)
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09382227 — Phenylethanolamine-based NMDA receptor antagonists

US 09382227	Furukawa et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Mental Health (NIMH)
APPLICANT(S)	Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
ASSIGNEE(S)	Cold Spring Harbor Laboratory (Cold Spring Harbor, New York)
INVENTOR(S)	Hiro Furukawa (Cold Spring Harbor, New York); Erkan Karakas (Huntington, New York)
ABSTRACT	Described herein are enhanced N-methyl-D-aspartate (NMDA) receptor antagonists, pharmaceutical compositions thereof, and their methods of use and treatment, e.g., of Formula (I): wherein one or more of R¹, R², R³, R⁴, R⁵, or the ring formed by the joining of R¹and R², is a hydrophobic moiety which confers enhanced antagonist activity as compared to existing NMDA receptor antagonists, e.g., ifenprodil. Compounds described herein are designed based on the discovery that ifenprodil binds within the allosteric domain of the GluN1/GluN2B NMDA receptor, particularly at the interface between GluN1 and GluN2B subunits. In silico methods are further described herein.
FILED	Thursday, January 02, 2014
APPL NO	14/146230
ART UNIT	1625 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/4422 (20130101) Heterocyclic Compounds C07D 211/14 (20130101) C07D 211/18 (20130101) C07D 211/22 (20130101) C07D 401/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) G01N 33/6896 (20130101) G01N 2333/70571 (20130101) G01N 2500/20 (20130101) Electric Digital Data Processing G06F 19/16 (20130101)
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09382229 — Compounds and methods of use thereof for treating neurodegenerative disorders

US 09382229	Zack et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	Donald J. Zack (Baltimore, Maryland); Cynthia Berlinicke (Baltimore, Maryland); Laszlo Hackler (Zagrab, Hungary); Zhiyong Yang (Baltimore, Maryland); Joseph P. Steiner (Mount Airy, Maryland); Tomas Vojkovsky (Palm Beach Gardens, Florida); Dana Ferraris (Eldersburg, Maryland); Barbara S. Slusher (Baltimore, Maryland); James Inglese (Bethesda, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Donald J. Zack (Baltimore, Maryland); Cynthia Berlinicke (Baltimore, Maryland); Laszlo Hackler (Zagrab, Hungary); Zhiyong Yang (Baltimore, Maryland); Joseph P. Steiner (Mount Airy, Maryland); Tomas Vojkovsky (Palm Beach Gardens, Florida); Dana Ferraris (Eldersburg, Maryland); Barbara S. Slusher (Baltimore, Maryland); James Inglese (Bethesda, Maryland)
ABSTRACT	Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
FILED	Wednesday, February 15, 2012
APPL NO	13/985702
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/12 (20130101) Original (OR) Class C07D 403/14 (20130101) C07D 453/02 (20130101)
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09382230 — Methods and compositions for modulating Ire1, SRC and ABL activity

US 09382230	Walter et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Peter Walter (San Francisco, California); Alexei Korennykh (San Francisco, California); Kevan M. Shokat (San Francisco, California); Chao Zhang (Santa Cruz, California); Janet Finer-Moore (San Bruno, California); Robert Stroud (San Francisco, California); Pascal Egea (San Francisco, California); Andrei Korostelev (Santa Cruz, California); Arvin Dar (San Francisco, California); Sebastian Bernales (Santiago, Chile)
ABSTRACT	Disclosed herein are, inter alia, compositions for modulating Ire1, Src, or Abl, methods for identifying modulating activity in test compounds, and methods for treating diseases caused by the activity or inactivity of Ire1, Src, or Abl.
FILED	Wednesday, July 02, 2014
APPL NO	14/322765
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/497 (20130101) A61K 31/4155 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/12 (20130101) Original (OR) Class C07D 403/14 (20130101)
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09382239 — Inhibitors of c-Jun-N-terminal kinase (JNK)

US 09382239	Gray et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Human Genome Research Institute (NHGRI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)	Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S)	Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts)
ABSTRACT	The present invention provides novel compounds according to Formula (I): where Ring A, Ring B, X, L₁, L₂, R^A, R^C, R^D, R^E, m, n, and p are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of human diseases associated with kinase activity, for example, proliferative diseases, neurodegenerative diseases, metabolic disorders, inflammatory diseases, and cardiovascular diseases.
FILED	Friday, November 16, 2012
APPL NO	14/358606
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/444 (20130101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 403/04 (20130101) C07D 403/06 (20130101) C07D 417/04 (20130101) Original (OR) Class C07D 417/06 (20130101) C07D 471/04 (20130101)
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09382245 — Compounds and methods for treating HIV infections

US 09382245	Jorgensen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Allergy and Infectious Diseases (NIAID) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S)	YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S)	William L. Jorgensen (Deep River, Connecticut); Karen S. Anderson (Guilford, Connecticut)
ABSTRACT	The present invention is directed to novel nanomolar and picomolar inhibitors of HIV reverse transcriptase, pharmaceutical compositions therefrom and methods for inhibiting reverse transcriptase and treating HIV infections, especially included drug resistant strains of HIV-1 and HIV-2 and/or secondary disease states and/or conditions which occur as a consequence of HIV infection.
FILED	Wednesday, October 08, 2014
APPL NO	14/509301
ART UNIT	1628 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) A61K 31/513 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/54 (20130101) C07D 403/12 (20130101) C07D 407/12 (20130101) C07D 471/04 (20130101) Original (OR) Class
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09382281 — Nickel pre-catalysts and related compositions and methods

US 09382281	Jamison et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Timothy F. Jamison (Somerville, Massachusetts); Eric Alan Standley (Cambridge, Massachusetts)
ABSTRACT	Described herein are nickel pre-catalysts and related compositions and methods. The nickel pre-catalysts may be activated to form catalysts which may be utilized in organic reactions.
FILED	Friday, November 07, 2014
APPL NO	14/535854
ART UNIT	1671 — Organic Chemistry
CURRENT CPC	Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/24 (20130101) B01J 31/2409 (20130101) B01J 31/2414 (20130101) B01J 2231/34 (20130101) B01J 2531/847 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/04 (20130101) Original (OR) Class
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09382302 — Lutzomyia longipalpis polypeptides and methods of use

US 09382302	Valenzuela et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Fundacao Oswaldo Cruz (FIOCRUZ) (Rio de Janeiro, Brazil)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia); Fundação Oswaldo Cruz (FIOCRUZ) (, Brazil)
INVENTOR(S)	Jesus G. Valenzuela (Gaithersburg, Maryland); Jose M. C. Ribeiro (Rockville, Maryland); Aldina Barral (Bahia, Brazil); Manoel Barral Netto (Bahia, Brazil); Claudia I. Brodskyn (Bahia, Brazil); Regis Gomes (Bahia, Brazil)
ABSTRACT	Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
FILED	Friday, July 17, 2015
APPL NO	14/802168
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0003 (20130101) A61K 39/008 (20130101) A61K 2039/53 (20130101) Peptides C07K 14/44 (20130101) Original (OR) Class C07K 14/43577 (20130101) C07K 16/18 (20130101) C07K 16/20 (20130101) C07K 2317/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101)
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09382310 — Expression of triple-helical collagen-like products in E. coli

US 09382310	Mirochnitchenko et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Oleg Mirochnitchenko (Rockville, Maryland); Masayori Inouye (New Brunswick, New Jersey); Barbara Brodsky (Brookline, Massachusetts); John Ramshaw (Pascoe Vale, Australia)
ASSIGNEE(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S)	Oleg Mirochnitchenko (Rockville, Maryland); Masayori Inouye (New Brunswick, New Jersey); Barbara Brodsky (Brookline, Massachusetts); John Ramshaw (Pascoe Vale, Australia)
ABSTRACT	Recombinant bacterial triple-helical collagen-like proteins comprising two or more repetitive sequences of Gly-Xaa-Yaa yielding high-stability polymeric constructs without the need for post-translational modifications and which may incorporate one or more functional domains of biological or structural importance. The polymers are capable of high-yield production for a variety of applications.
FILED	Friday, February 05, 2010
APPL NO	13/148066
ART UNIT	1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Peptides C07K 14/78 (20130101) Original (OR) Class
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09382311 — HIV-1 broadly neutralizing antibodies

US 09382311	Mascola et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
ASSIGNEE(S)	INTERNATIONAL AIDS VACCINE INITIATIVE (New York, New York); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Washington, District of Columbia)
INVENTOR(S)	John Mascola (Rockville, Maryland); Dennis R. Burton (La Jolla, California); Wayne Koff (Stony Brook, New York); Peter Kwong (Washington, District of Columbia); Gary Nabel (Washington, District of Columbia); Sanjay K. Phogat (Edison, New Jersey); Pascal Raymond Georges Poignard (San Diego, California); Melissa Danielle De Jean St. Marcel Simek-Lemos (Brooklyn, New York); Xueling Wu (Potomac, Maryland); Tongqing Zhou (Boyds, Maryland); Zhi-Yong Yang (Potomac, Maryland)
ABSTRACT	The present application relates broadly neutralizing monoclonal antibodies directed against HIV-1. In particular, monoclonal antibodies VRC-PG04 and VRC-PG05 are disclosed.
FILED	Sunday, March 10, 2013
APPL NO	13/792098
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/76 (20130101)
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09382313 — Modulation of synaptic maintenance

US 09382313	Barres et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Ben A. Barres (Palo Alto, California); Beth A. Stevens (Milton, Massachusetts)
ABSTRACT	C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease.
FILED	Friday, June 26, 2015
APPL NO	14/751921
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/727 (20130101) A61K 31/727 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/5058 (20130101) G01N 33/6872 (20130101) G01N 33/6896 (20130101) G01N 2333/4716 (20130101) G01N 2500/04 (20130101) G01N 2800/28 (20130101) G01N 2800/2821 (20130101)
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09382314 — Modulation of synaptic maintenance

US 09382314	Barres et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI) National Institute on Drug Abuse (NIDA)
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S)	Ben A. Barres (Palo Alto, California); Beth A. Stevens (Milton, Massachusetts)
ABSTRACT	C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease.
FILED	Friday, June 26, 2015
APPL NO	14/751967
ART UNIT	1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/727 (20130101) A61K 31/727 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/5058 (20130101) G01N 33/6872 (20130101) G01N 33/6896 (20130101) G01N 2333/4716 (20130101) G01N 2500/04 (20130101) G01N 2800/28 (20130101) G01N 2800/2821 (20130101)
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09382324 — Monoclonal antibodies to fibroblast growth factor receptor 2

US 09382324	Kim et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	GALAXY BIOTECH, LLC (Cupertino, California)
ASSIGNEE(S)	GALAXY BIOTECH, LLC (Cupertino, California)
INVENTOR(S)	Kyung Jin Kim (Cupertino, California); Wei-meng Zhao (Palo Alto, California); Hangil Park (San Francisco, California); Maximiliano Vasquez (Palo Alto, California)
ABSTRACT	The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.
FILED	Monday, November 04, 2013
APPL NO	14/071520
ART UNIT	1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/92 (20130101)
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09382387 — Rapid self-assembly of block copolymers to photonic crystals

US 09382387	Xia et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	California Institute of Technology (Pasadena, California); The University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Yan Xia (Quincy, Massachusetts); Benjamin R Sveinbjornsson (Pasadena, California); Robert H Grubbs (South Pasadena, California); Raymond Weitekamp (Glendale, California); Garret M Miyake (Pasadena, California); Harry A Atwater (South Pasadena, California); Victoria Piunova (Altadena, California); Christopher Scot Daeffler (Pasadena, California); Sung Woo Hong (Seoul, South Korea); Weiyin Gu (Amherst, Massachusetts); Thomas P. Russell (Amherst, Massachusetts)
ABSTRACT	The invention provides a class of copolymers having useful properties, including brush block copolymers, wedge-type block copolymers and hybrid wedge and polymer block copolymers. In an embodiment, for example, block copolymers of the invention incorporate chemically different blocks comprising polymer size chain groups and/or wedge groups that significantly inhibit chain entanglement, thereby enhancing molecular self-assembly processes for generating a range of supramolecular structures, such as periodic nanostructures and microstructures. The present invention also provides useful methods of making and using copolymers, including block copolymers.
FILED	Wednesday, March 13, 2013
APPL NO	13/800646
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/027 (20130101) Original (OR) Class C08G 83/008 (20130101)
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09382473 — Chromophoric polymer dots

US 09382473	Chiu et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI) National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)	Daniel T. Chiu (Seattle, Washington); Changfeng Wu (Changchun, China PRC); Xuanjun Zhang (Linköping, Sweden); Jiangbo Yu (Seattle, Washington); Fangmao Ye (Seattle, Washington)
ASSIGNEE(S)	University of Washington Through Its Center for Commercialization (Seattle, Washington)
INVENTOR(S)	Daniel T. Chiu (Seattle, Washington); Changfeng Wu (Changchun, China PRC); Xuanjun Zhang (Linköping, Sweden); Jiangbo Yu (Seattle, Washington); Fangmao Ye (Seattle, Washington)
ABSTRACT	The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.
FILED	Thursday, April 18, 2013
APPL NO	13/865924
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/588 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0039 (20130101)
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09382515 — Reprogramming of somatic cells

US 09382515	Jaenisch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	Rudolf Jaenisch (Brookline, Massachusetts); Yaqub Hanna (Boston, Massachusetts); Marius Wernig (Woodside, California); Christopher J. Lengner (Wellesley, Massachusetts); Alexander Meissner (Cambridge, Massachusetts); Oliver Tobias Brambrink (Cambridge, Massachusetts); G. Grant Welstead (Cambridge, Massachusetts); Ruth Foreman (Somerville, Massachusetts)
ASSIGNEE(S)	Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S)	Rudolf Jaenisch (Brookline, Massachusetts); Yaqub Hanna (Boston, Massachusetts); Marius Wernig (Woodside, California); Christopher J. Lengner (Wellesley, Massachusetts); Alexander Meissner (Cambridge, Massachusetts); Oliver Tobias Brambrink (Cambridge, Massachusetts); G. Grant Welstead (Cambridge, Massachusetts); Ruth Foreman (Somerville, Massachusetts)
ABSTRACT	The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells.
FILED	Monday, April 07, 2008
APPL NO	12/595041
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0273 (20130101) A01K 67/0275 (20130101) A01K 2217/05 (20130101) A01K 2227/105 (20130101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 15/8509 (20130101) C12N 15/8775 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2506/11 (20130101) C12N 2506/13 (20130101) C12N 2800/30 (20130101) C12N 2830/003 (20130101) C12N 2830/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 2333/91011 (20130101)
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09382531 — Induction of hemogenic endothelium from pluripotent stem cells

US 09382531	Slukvin et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S)	Igor Slukvin (Verona, Wisconsin); Irina Elcheva (Madison, Wisconsin)
ABSTRACT	Described herein are methods and related compositions for inducing differentiation of human pluripotent stem cells (hPSCs) into hemogenic endothelium with pan-myeloid potential or restricted potential, by forced expression in the hPSCs of a combination of transcription factors as described herein.
FILED	Monday, October 21, 2013
APPL NO	14/058959
ART UNIT	1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 15/00 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/66 (20130101) C12N 2501/60 (20130101) C12N 2501/998 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2740/16043 (20130101)
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09382584 — Methods and systems for direct sequencing of single DNA molecules

US 09382584	Huang
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Human Genome Research Institute (NHGRI)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Xiaohua Huang (La Jolla, California)
ABSTRACT	The invention provides improved methods for sequencing nucleic acids, e.g., for medical applications and biomedical research. The disclosed methods can be applied to rapid personalized medicine, genetic diagnosis, pathogen identification, and sequencing species genomes.
FILED	Friday, March 28, 2014
APPL NO	14/229621
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1252 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2565/101 (20130101)
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09382592 — Primers and probes for detection and discrimination of types and subtypes of influenza viruses

US 09382592	Lindstrom et al.
FUNDED BY	Department of Health and Human Services (HHS) Centers for Disease Control and Prevention (CDC)
APPLICANT(S)	The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Department of (Washington, District of Columbia)
INVENTOR(S)	Stephen Lindstrom (Atlanta, Georgia); Alexander Klimov (, None); Nancy Cox (Atlanta, Georgia); Lamorris Loftin (Philadelphia, Pennsylvania)
ABSTRACT	Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
FILED	Thursday, October 17, 2013
APPL NO	14/056810
ART UNIT	1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class C12Q 1/6837 (20130101)
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09383312 — Electro-optic grating-coupled surface plasmon resonance (EOSPR)

US 09383312	Page et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	Ciencia, Inc. (East Hartford, Connecticut)
ASSIGNEE(S)	Ciencia, Inc. (East Hartford, Connecticut)
INVENTOR(S)	William Page (Storrs, Connecticut); George N. Gibson (Storrs, Connecticut); Ernest F. Guignon (Canton, Connecticut)
ABSTRACT	An instrument for measuring and analyzing surface plasmon resonance (SPR) and/or surface plasmon coupled emission on an electro-optic grating-coupled sensor surface is described herein. The sensor chip achieves SPR through a grating-coupled approach, with variations in the local dielectric constant at regions of interest (ROI) at the sensor surface detected as a function of the intensity of light reflecting from these ROI. Unlike other grating-based approaches, the metal surface is sufficiently thin that resonant conditions are sensitive to dielectric constant changes both above and below the metal surface (like the Kretschmann configuration). Dielectric constant shifts that occur as mass accumulates on the surface can be returned to reference intensities by applying voltage across the underlying electro-optic polymer. Approaches to the development of the sensor surfaces are described, as are software and hardware features facilitating sample handling, data gathering, and data analysis by this solid-state approach.
FILED	Thursday, November 06, 2014
APPL NO	14/534511
ART UNIT	2886 — Optics
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/553 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/061 (20130101) G02F 1/195 (20130101)
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09383348 — Compositions and methods for treating lung disorders

US 09383348	Repine
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	John E. Repine (Denver, Colorado)
ASSIGNEE(S)	John E. Repine (Aurora, Colorado)
INVENTOR(S)	John E. Repine (Denver, Colorado)
ABSTRACT	The present invention relates to methods of treating subjects with alveolar capillary membrane injury or methods of preventing alveolar capillary membrane injury in subjects, with the methods comprising administering to the subjects a therapeutically effective amount of ergothioneine and a pharmaceutically acceptable carrier. The invention also relates to methods of screening candidate compounds for their ability to mitigate the effects of alveolar capillary membrane injury.
FILED	Monday, June 22, 2009
APPL NO	13/000603
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) A61K 31/385 (20130101) A61K 31/4164 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Original (OR) Class G01N 2500/10 (20130101) G01N 2800/12 (20130101) G01N 2800/125 (20130101)
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09383352 — Salivary protein glycosylation test for diagnosis and monitoring of diabetes

US 09383352	Nagalla et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S)	DiabetOmics, LLC (Hillsboro, Oregon)
ASSIGNEE(S)	Diabetomics, Inc. (Hillsboro, Oregon)
INVENTOR(S)	Srinivasa R. Nagalla (Hillsboro, Oregon); Eric S. Bean (Wilsonville, Oregon)
ABSTRACT	Disclosed herein are methods and tests for diagnosing and/or monitoring a metabolic condition such as diabetes in a subject, wherein the methods and tests measure salivary glycoproteins. Some of the methods are based on the oxidation of glycoproteins in a sample from the subject, such as saliva or urine, for example using sodium metaperiodate, and then detecting the aldehydes generated during oxidation using a chemical detection method. Also disclosed are kits and lateral flow devices for detecting glycoproteins in a saliva sample.
FILED	Wednesday, March 26, 2014
APPL NO	14/226131
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) G01N 33/66 (20130101) G01N 33/525 (20130101) Original (OR) Class G01N 33/6872 (20130101) G01N 2800/042 (20130101) G01N 2800/56 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/143333 (20150115) Y10T 436/144444 (20150115) Y10T 436/200833 (20150115)
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09383355 — Methods and related devices for continuous sensing utilizing magnetic beads

US 09383355	Sasso, Jr. et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)	Lawrence A. Sasso, Jr. (New Brunswick, New Jersey); Jeffrey Zahn (Princeton, New Jersey)
ASSIGNEE(S)	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S)	Lawrence A. Sasso, Jr. (New Brunswick, New Jersey); Jeffrey Zahn (Princeton, New Jersey)
ABSTRACT	Provided is a fluidic device including a main channel, wherein a first inlet fluidly connects to an upstream end of the main channel and introduces magnetic beads into a first side of the main channel. A second inlet is fluidly connected to the upstream end of the main channel and introduces a sample stream into a second side of the main channel. A magnet disposed adjacent to the second side of the main channel pulls the magnetic beads towards a sidewall of the second side, and thus into the sample stream. The beads continue through an extended incubation channel before entering a return channel. The return channel includes a detection region. Also provided is a multi-layer micro-fluidic assay device. An assay method that utilizes a microfluidic assay device is provided as well.
FILED	Monday, April 16, 2012
APPL NO	13/448322
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) B01L 2400/043 (20130101) B01L 2400/084 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1484 (20130101) G01N 21/05 (20130101) G01N 21/64 (20130101) G01N 33/54333 (20130101) Original (OR) Class G01N 33/54366 (20130101) G01N 2021/0346 (20130101)
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09383357 — Biomarker for replicative senescence

US 09383357	Goldman et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Cancer Institute (NCI)
APPLICANT(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S)	NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S)	Robert D. Goldman (Chicago, Illinois); Takeshi Shimi (Chicago, Illinois); Stephen A. Adam (Glenview, Illinois)
ABSTRACT	The present invention provides biomarkers for replicative senescence. In particular, Lamin B1 is provided as a biomarker for replicative senescence.
FILED	Friday, December 06, 2013
APPL NO	14/099444
ART UNIT	1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) Original (OR) Class G01N 2333/78 (20130101)
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09383360 — Compositions and methods relating to lyme disease

US 09383360	Russell et al.
FUNDED BY	Department of Health and Human Services (HHS)
APPLICANT(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Atlanta, Georgia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland)
INVENTOR(S)	Theresa M. Russell (Fort Collins, Colorado); Barbara J. B. Johnson (Fort Collins, Colorado)
ABSTRACT	Compositions and methods of the present invention relating to B. burgdorferi HtrA sensu lato (BbHtrA) protease activity, its substrates, cleavage products, biological effects and use in detection, diagnosis and/or treatment of Lyme disease are provided.
FILED	Monday, January 21, 2013
APPL NO	14/372171
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Peptides C07K 16/12 (20130101) C07K 2317/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 33/581 (20130101) G01N 33/6863 (20130101) G01N 33/6869 (20130101) G01N 33/56911 (20130101) G01N 2333/20 (20130101) G01N 2333/952 (20130101) G01N 2469/10 (20130101) G01N 2469/20 (20130101) G01N 2800/26 (20130101) G01N 2800/52 (20130101)
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09383364 — Predictive marker of DNMT1 inhibitor therapeutic efficacy and methods of using the marker

US 09383364	Bates et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Research Resources (NCRR)
APPLICANT(S)	Paula J. Bates (Louisville, Kentucky); Mohammad Tariq Malik (Prospect, Kentucky); Francesca R. Salipur (Louisville, Kentucky)
ASSIGNEE(S)	University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S)	Paula J. Bates (Louisville, Kentucky); Mohammad Tariq Malik (Prospect, Kentucky); Francesca R. Salipur (Louisville, Kentucky)
ABSTRACT	Provided herein are methods for predicting efficacy of a DNA (cytosine-5)-methyltransferase 1 (DNMT1) inhibitor treatment in a subject having a cancer, methods of identifying a subject having a cancer that is more likely to respond to a DNMT1 inhibitor treatment, and methods of selecting a treatment for a subject having a cancer that include determining a level of SOX9 in a sample containing cells from a subject having a cancer. Also provided are methods of treating a subject having a cancer that include selectively administering a DNMT1 inhibitor to a subject having cancer determined to have an elevated level of SOX9 in a sample containing cells from the subject compared to a reference level. Also provided are antibodies and antigen-binding antibody fragments that specifically bind to SOX9, and nucleic acid sequences that contain at least 10 nucleotides complementary to a contiguous sequence present in a SOX9 nucleic acid for use in these methods.
FILED	Wednesday, March 07, 2012
APPL NO	14/003714
ART UNIT	1629 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/045 (20130101) Peptides C07K 16/18 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/5748 (20130101) Original (OR) Class
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09383374 — Methods to determine susceptibility to treatment with leukotriene modifiers

US 09383374	Rabinovitch et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S)	NATIONAL JEWISH HEALTH (Denver, Colorado)
ASSIGNEE(S)	National Jewish Health (Denver, Colorado)
INVENTOR(S)	Nathan Rabinovitch (Denver, Colorado); Erwin Gelfand (Englewood, Colorado)
ABSTRACT	The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and the subject's level of eosinophilic airway inflammation and identifying a subject with a high ratio of CysLT levels to eosinophilic airway inflammation as susceptible to treatment with the leukotriene modifier. Also discussed is a method of treatment of subjects who are susceptible to treatment that includes administering a leukotriene modifier to such a subject.
FILED	Tuesday, February 11, 2014
APPL NO	14/177441
ART UNIT	1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/88 (20130101) Original (OR) Class G01N 33/497 (20130101) G01N 2033/4975 (20130101) G01N 2800/24 (20130101) G01N 2800/52 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/177692 (20150115)
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09383423 — Systems and methods for susceptibility tensor imaging

US 09383423	Liu
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)	Chunlei Liu (Chapel Hill, North Carolina)
ASSIGNEE(S)
INVENTOR(S)	Chunlei Liu (Chapel Hill, North Carolina)
ABSTRACT	The present disclosure provides a method and system for quantifying and making images of tissue anisotropy property based on magnetic resonance imaging (MRI). The systems and methods provided herein utilize orientation distribution of magnetic susceptibility to characterize magnetic susceptibility anisotropy (MSA) inside biological tissues. This MSA may be intrinsic property of the tissue or may be induced by the presence of external agents. In certain embodiments, the MSA is displayed as an orientation distribution function of susceptibility and/or may be described by mathematical quantities such as tensors (e.g., symmetric or asymmetric second order or higher order tensors) and spherical harmonics. In other embodiments, the MSA is characterized using a second order tensor named apparent susceptibility tensor (AST).
FILED	Thursday, May 09, 2013
APPL NO	13/891181
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/48 (20130101) G01R 33/54 (20130101) Original (OR) Class G01R 33/243 (20130101) G01R 33/56383 (20130101)
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09383568 — Objective-coupled selective plane illumination microscopy

US 09383568	Holy et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)	Timothy E. Holy (St. Louis, Missouri); Terrence F. Holekamp (St. Louis, Missouri)
ASSIGNEE(S)	WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S)	Timothy E. Holy (St. Louis, Missouri); Terrence F. Holekamp (St. Louis, Missouri)
ABSTRACT	A microscope assembly includes an illumination source coupled to an optical assembly by a coupler. The optical assembly includes an objective with optics that move along an optic axis. The illumination source generates a light blade that illuminates a portion of a sample at an illumination plane. The light blade induces a fluorescent emission from the sample that is projected through the objective optics to a detector. The focal plane of the objective optics is fixed with respect to the illumination source by the coupler so that the illumination plane is coincident with the focal plane as the objective optics move along the optic axis. The objective and illumination may be rapidly scanned along the optic axis to provide rapid three-dimensional imaging while the objective and illumination may also be rapidly scanned along the optic axis to provide rapid three-dimensional imaging.
FILED	Wednesday, August 01, 2012
APPL NO	13/564582
ART UNIT	2872 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 21/006 (20130101) G02B 21/008 (20130101) G02B 21/08 (20130101) G02B 21/16 (20130101) Original (OR) Class
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09384404 — Apparatus and method for capturing a vital vascular fingerprint

US 09384404	Chen et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Zhongping Chen (Irvine, California); Gangjun Liu (Irvine, California)
ABSTRACT	A method using optical coherence tomography to capture the microvascular network of the superficial layer of the finger skin for the purpose of fingerprint authentication and liveness detection. At the dermal papilla region, the vascular pattern follows the same pattern of the fingerprint and this vascular pattern forms a live vascular fingerprint. This live vascular fingerprint provides for ultrahigh security and a unique way for fingerprint-based personal verification. Because the system is based on blood flow, which only exists in a living person, the technique is robust against spoof attaching. After performing non-contact in-vivo imaging of a human fingertip, a three dimensional vasculature image is reconstructed from a plurality of vasculature tomography images and at least one vasculature fingerprint image which corresponds to the fingertip is extracted from the three dimensional vasculature image. This extracted image may then be compared to known fingerprint database for authentication or for liveness detection.
FILED	Friday, February 28, 2014
APPL NO	14/194415
ART UNIT	2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00885 (20130101) Original (OR) Class G06K 2009/0006 (20130101) G06K 2009/00932 (20130101)
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09384582 — Methods and computer program products for quantitative three-dimensional image correction and clinical parameter computation in optical coherence tomography

US 09384582	Izatt et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Eye Institute (NEI)
APPLICANT(S)	DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S)	Duke University (Durham, North Carolina)
INVENTOR(S)	Joseph A. Izatt (Raleigh, North Carolina); Mingtao Zhao (Durham, North Carolina); Anthony N. Kuo (Durham, North Carolina)
ABSTRACT	Methods and computer program products for quantitative three-dimensional (“3D”) image correction in optical coherence tomography. Using the methods and computer program products, index interface (refracting) surfaces from the raw optical coherence tomography (“OCT”) dataset from an OCT system can be segmented. Normal vectors or partial derivatives of the curvature at a refracting surface can be calculated to obtain a refracted image voxel. A new position of each desired refracted image voxel can be iteratively computed. New refracted corrected voxel positions to an even sampling grid can be interpolated to provide corrected image data. In some embodiments, clinical outputs from the corrected image data can be computed.
FILED	Friday, March 07, 2014
APPL NO	13/999539
ART UNIT	2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02083 (20130101) G01B 9/02091 (20130101) G01B 11/2441 (20130101) Image Data Processing or Generation, in General G06T 5/006 (20130101) G06T 15/00 (20130101) Original (OR) Class G06T 2207/10101 (20130101) G06T 2207/30041 (20130101)
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09385692 — Low power oscillator with charge subtraction scheme

US 09385692	Blaauw et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents Of The University Of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	David T. Blaauw (Ann Arbor, Michigan); Dennis Sylvester (Ann Arbor, Michigan); Seok Hyeon Jeong (Ann Arbor, Michigan)
ABSTRACT	An ultra-low power oscillator is designed for wake-up timers that can be used in compact wireless sensors, for example. A constant charge subtraction scheme removes continuous comparator delay from the oscillation period, which is the source of temperature dependence in conventional RC relaxation oscillators. This relaxes comparator design constraints, enabling low power operation. In 0.18 μm CMOS, the oscillator consumes 5.8 nW at room temperature with temperature stability of 45 ppm/° C. (−10° C. to 90° C.) and 1%/V line sensitivity.
FILED	Wednesday, March 18, 2015
APPL NO	14/661279
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 3/011 (20130101) H03K 3/012 (20130101) H03K 3/0231 (20130101) Original (OR) Class H03K 4/502 (20130101)
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09386027 — Detection of pileup vulnerabilities in mobile operating systems

US 09386027	Xing et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	Luyi Xing (Bloomington, Indiana); XiaoFeng Wang (Bloomington, Indiana)
ABSTRACT	A system is provided for detecting pileup vulnerabilities corresponding to mobile operating system updates. The system includes: an exploit opportunity analyzer, configured to identify pileup exploit opportunities corresponding to a plurality of mobile operating system configurations based on mobile operating system upgrades for each of the plurality of mobile operating system configurations, wherein the identification of exploit opportunities is based on information relating to pileup flaws; a risk database, configured to store information regarding the identified pileup exploit opportunities for a plurality of versions of each of the plurality of mobile operating system configurations; and a scanner application, configured to be executed by a mobile device, configured to query identified exploit opportunities relating to a particular mobile operating system configuration and version, and to evaluate third-party applications installed at the mobile device based on the identified exploit opportunities.
FILED	Monday, August 11, 2014
APPL NO	14/456719
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/14 (20130101) Original (OR) Class
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Department of Defense (DOD)

09380952 — Body-worn system for continuous, noninvasive measurement of cardiac output, stroke volume, cardiac power, and blood pressure

US 09380952	Banet et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S)	Matt Banet (Kihei, Hawaii); Isaac Henry (La Mesa, California); Donald Bernstein (Rancho Santa Fe, California)
ASSIGNEE(S)	SOTERA WIRELESS, INC. (San Diego, California)
INVENTOR(S)	Matt Banet (Kihei, Hawaii); Isaac Henry (La Mesa, California); Donald Bernstein (Rancho Santa Fe, California)
ABSTRACT	The invention provides a system for measuring stroke volume (SV), cardiac output (CO), and cardiac power (CP) from a patient that features: 1) an impedance sensor connected to at least two body-worn electrodes and including an impedance circuit that processes analog signals from the electrodes to measure an impedance signal (e.g. a TBEV waveform); 2) an ECG sensor connected to at least two chest-worn electrodes and including an ECG circuit that processes analog signals from the electrodes to measure and ECG signal; 3) an optical sensor connected to a body-worn optical probe and including an optical circuit that processes signals from the probe to measure at least one optical signal (e.g. a PPG waveform) from the patient; 4) a processing system, typically worn on the patient's wrist and connected through a wired interface to the optical sensor, and through either a wired or wireless interface to the TBEV and ECG sensors. The processing system analyzes the ECG, TBEV and optical signals to determine SV, and further analyzes SV and HR determined from an ECG sensor to determine CO.
FILED	Wednesday, December 28, 2011
APPL NO	13/338518
ART UNIT	3766 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/021 (20130101) A61B 5/029 (20130101) A61B 5/0295 (20130101) Original (OR) Class A61B 5/0535 (20130101) A61B 5/681 (20130101) A61B 5/746 (20130101) A61B 5/0816 (20130101) A61B 5/1116 (20130101) A61B 5/6823 (20130101) A61B 5/6824 (20130101) A61B 5/6826 (20130101) A61B 5/6833 (20130101) A61B 5/7239 (20130101) A61B 5/14551 (20130101) A61B 2562/04 (20130101)
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09381099 — Arm prosthetic device

US 09381099	Perry et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Research, Development and Engineering Command (RDECOM)
APPLICANT(S)	N. Christopher Perry (Manchester, New Hampshire); Christopher O. Evans (Amherst, New Hampshire); Dirk A. van der Merwe (Canterbury, New Hampshire); Stewart M Coulter (Bedford, New Hampshire); Keith D. Violette (Sandown, New Hampshire); Thomas A. Doyon (Manchester, New Hampshire)
ASSIGNEE(S)	DEKA Products Limited Partnership (Manchester, New Hampshire)
INVENTOR(S)	N. Christopher Perry (Manchester, New Hampshire); Christopher O. Evans (Amherst, New Hampshire); Dirk A. van der Merwe (Canterbury, New Hampshire); Stewart M Coulter (Bedford, New Hampshire); Keith D. Violette (Sandown, New Hampshire); Thomas A. Doyon (Manchester, New Hampshire)
ABSTRACT	A system for powering a prosthetic arm is disclosed. The system includes at least one internal battery located in the prosthetic arm, at least one external battery connected to the prosthetic arm, and a master controller configured to connect either the at least one internal battery or the at least one external battery to a power bus to power the prosthetic arm.
FILED	Friday, August 03, 2012
APPL NO	13/566736
ART UNIT	3738 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/68 (20130101) A61F 2/70 (20130101) Original (OR) Class A61F 2/78 (20130101) A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/587 (20130101) A61F 2002/701 (20130101) A61F 2002/702 (20130101) A61F 2002/704 (20130101) A61F 2002/705 (20130101) A61F 2002/708 (20130101) A61F 2002/747 (20130101) A61F 2002/764 (20130101) A61F 2002/768 (20130101) A61F 2002/769 (20130101) A61F 2002/5001 (20130101) A61F 2002/5061 (20130101) A61F 2002/5083 (20130101) A61F 2002/6836 (20130101) A61F 2002/6845 (20130101) A61F 2002/6881 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7665 (20130101) A61F 2002/7862 (20130101) A61F 2002/30464 (20130101) A61F 2220/0075 (20130101) A61F 2250/008 (20130101) A61F 2250/0074 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 19/005 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 41/12 (20130101) F16D 41/105 (20130101)
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09381158 — Nanoparticle fabrication methods, systems, and materials for fabricating artificial red blood cells

US 09381158	DeSimone et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Joseph M. DeSimone (Chapel Hill, North Carolina); Edward T. Samulski (Chapel Hill, North Carolina)
ABSTRACT	A plurality of artificial red blood cell particles includes each particle of the plurality being substantially monodisperse and each particle having a largest common linear dimension of about 5 μm to about 10 μm. The particles can also have a modulus configured such that a particle of the plurality of particles can pass through a tube having an inner diameter of less than about 3 μm.
FILED	Wednesday, May 29, 2013
APPL NO	13/904517
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0026 (20130101) A61K 9/1641 (20130101) Original (OR) Class A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 35/18 (20130101) A61K 38/42 (20130101) A61K 47/34 (20130101) A61K 51/1244 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 2400/12 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 71/02 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/832 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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09381528 — Articles for manipulating impinging liquids and methods of manufacturing same

US 09381528	Dhiman et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Rajeev Dhiman (Glastonbury, Connecticut); James C. Bird (Cambridge, Massachusetts); Hyukmin Kwon (Cambridge, Massachusetts); Kripa K. Varanasi (Lexington, Massachusetts)
ABSTRACT	This invention relates generally to an article that includes a non-wetting surface having a dynamic contact angle of at least about 90°. The surface is patterned with macro-scale features configured to induce controlled asymmetry in a liquid film produced by impingement of a droplet onto the surface, thereby reducing time of contact between the droplet and the surface.
FILED	Wednesday, June 11, 2014
APPL NO	14/302112
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/26 (20130101) Original (OR) Class Processes for Applying Fluent Materials to Surfaces, in General B05D 1/185 (20130101) B05D 5/02 (20130101) B05D 5/083 (20130101) Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24355 (20150115)
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09381703 — Apparatus for reducing porosities in composite resin parts

US 09381703	Misciagna
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S)	David Thomas Misciagna (West Chester, Pennsylvania)
ABSTRACT	An electrical charge is placed on a tool used to cure a composite resin part layup. The charged tool produces an electrostatic force that attracts entrapped gases in the resin to the surface of the tool, thereby reducing porosities in the cured part.
FILED	Wednesday, July 22, 2015
APPL NO	14/805862
ART UNIT	1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/02 (20130101) B29C 37/0064 (20130101) B29C 70/34 (20130101) Original (OR) Class B29C 70/44 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/10 (20150115)
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09381979 — Portable lightweight apparatus and method for transferring heavy loads

US 09381979	Galway
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Robert J. Galway (Virginia Beach, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Robert J. Galway (Virginia Beach, Virginia)
ABSTRACT	A method and apparatus for the water-based transfer of heavy loads. The invention is a lightweight apparatus is reconfigurable, and it includes a gantry arrangement mounted on beams or a platform and the apparatus is used to transfer heavy load items. The apparatus reconfigurable and may be used in a water-based loading environments in performing a variety of loading functions in situations involving one or more watercrafts and/or a pier or the like.
FILED	Tuesday, February 26, 2013
APPL NO	13/776861
ART UNIT	3654 — Material and Article Handling
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 7/00 (20130101) B63B 27/30 (20130101) Original (OR) Class Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles B66C 11/00 (20130101) B66C 23/52 (20130101)
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09382168 — Solid electrically controlled propellants

US 09382168	McPherson
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Missile Defense Agency (MDA)
APPLICANT(S)	Digital Solid State Propulsion, LLC (Reno, Nevada)
ASSIGNEE(S)	Digital Solid State Propulsion LLC (Reno, Nevada)
INVENTOR(S)	Michael D. McPherson (Reno, Nevada)
ABSTRACT	The present application discloses a variety of improvements that enhance at least one of the mechanical, chemical/energetic, ballistic, or adhesive properties, of a class of ECPs, regardless of whether said ECPs are in solid phase or gels, singly or in combinations thereof.
FILED	Tuesday, August 27, 2013
APPL NO	14/011677
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/10 (20130101) Original (OR) Class
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09382230 — Methods and compositions for modulating Ire1, SRC and ABL activity

US 09382230	Walter et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Medical Research and Development Command (USAMRDC) U.S. Army Medical Research and Materiel Command (USAMRMC) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Peter Walter (San Francisco, California); Alexei Korennykh (San Francisco, California); Kevan M. Shokat (San Francisco, California); Chao Zhang (Santa Cruz, California); Janet Finer-Moore (San Bruno, California); Robert Stroud (San Francisco, California); Pascal Egea (San Francisco, California); Andrei Korostelev (Santa Cruz, California); Arvin Dar (San Francisco, California); Sebastian Bernales (Santiago, Chile)
ABSTRACT	Disclosed herein are, inter alia, compositions for modulating Ire1, Src, or Abl, methods for identifying modulating activity in test compounds, and methods for treating diseases caused by the activity or inactivity of Ire1, Src, or Abl.
FILED	Wednesday, July 02, 2014
APPL NO	14/322765
ART UNIT	1624 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/497 (20130101) A61K 31/4155 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/12 (20130101) Original (OR) Class C07D 403/14 (20130101)
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09382352 — Polymers derived from plant oil

US 09382352	Chisholm et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	Bret Ja Chisholm (West Fargo, North Dakota); Samim Alam (Fargo, North Dakota)
ASSIGNEE(S)	NDSU Research Foundation (Fargo, North Dakota)
INVENTOR(S)	Bret Ja Chisholm (West Fargo, North Dakota); Samim Alam (Fargo, North Dakota)
ABSTRACT	Polymers and copolymers are formed from vinylether monomers having fatty acid ester pendent groups derived from plant oils, such as soybean oil.
FILED	Friday, May 11, 2012
APPL NO	13/469940
ART UNIT	1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/06 (20130101) C08F 8/06 (20130101) C08F 8/08 (20130101) C08F 8/08 (20130101) C08F 8/10 (20130101) C08F 22/20 (20130101) Original (OR) Class C08F 116/14 (20130101) C08F 116/14 (20130101) C08F 216/18 (20130101) C08F 216/1416 (20130101) C08F 2800/20 (20130101) C08F 2810/30 (20130101)
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09382547 — Human optimized Bacillus anthracis protective antigen

US 09382547	Goldman et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Stanley Goldman (Walnut Creek, California); Mark Albrecht (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Stanley Goldman (Walnut Creek, California); Mark Albrecht (Washington, District of Columbia)
ABSTRACT	The invention relates to a humanized nucleic acid construct from Bacillus anthracis protective antigen (PA) gene and method of modifying the gene. The humanized gene, and method of producing it, improves the structural fidelity of expressed protein product, when produced in mammalian host cells, to native, bacterially produced protein. The construct is useful in nucleic acid based vaccine formulations against B. anthracis.
FILED	Wednesday, February 26, 2014
APPL NO	14/190464
ART UNIT	1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/07 (20130101) A61K 2039/53 (20130101) A61K 2039/55511 (20130101) Peptides C07K 14/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) Original (OR) Class
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09382554 — Methods for isoprene and pinene production in cyanobacteria

US 09382554	Kallas et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Toivo Kallas (Oshkosh, Wisconsin); Matthew Nelson (Oshkosh, Wisconsin); Eric Singsaas (Stevens Point, Wisconsin)
ASSIGNEE(S)	WISYS TECHNOLOGY FOUNDATION, INC. (Madison, Wisconsin)
INVENTOR(S)	Toivo Kallas (Oshkosh, Wisconsin); Matthew Nelson (Oshkosh, Wisconsin); Eric Singsaas (Stevens Point, Wisconsin)
ABSTRACT	Methods of isoprenoid production are provided by the present invention. In particular, transgenic Synechococcus sp. PCC 7002 cyanobacteria and methods for producing isoprene and pinene using a host transgenic Synechococcus sp. PCC 7002 cyanobacterium are provided.
FILED	Friday, July 26, 2013
APPL NO	13/952071
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/90 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 5/007 (20130101) C12P 5/026 (20130101) Original (OR) Class Enzymes C12Y 402/03027 (20130101) C12Y 503/03002 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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09382590 — Methods and compositions for prostate cancer metastasis

US 09382590	Reams
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (FAMU) (Tallahassee, Florida)
ASSIGNEE(S)	FLORIDA AGRICULTURAL AND MECHANICAL UNIVERSITY (FAMU) (Tallahassee, Florida)
INVENTOR(S)	Romonia Renee Reams (Tallahassee, Florida)
ABSTRACT	Provided are methods and compositions for determining an increased likelihood of prostate cancer cells in a subject to metastasize.
FILED	Wednesday, May 20, 2015
APPL NO	14/717248
ART UNIT	1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101)
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09382605 — Economic oxidation and fatigue resistant metallic coating

US 09382605	Tryon et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S)	United Technologies Corporation (Farmington, Connecticut)
INVENTOR(S)	Brian S. Tryon (Glastonbury, Connecticut); David A. Litton (West Hartford, Connecticut); Russell A. Beers (Manchester, Connecticut)
ABSTRACT	The present disclosure relates to an improved low-cost metallic coating to be deposited on gas turbine engine components. The metallic coating consists of 1.0 to 18 wt % cobalt, 3.0 to 18 wt % chromium, 5.0 to 15 wt % aluminum, 0.01 to 1.0 wt % yttrium, 0.01 to 0.6 wt % hafnium, 0.0 to 0.3 wt % silicon, 0.0 to 1.0 wt % zirconium, 0.0 to 10 wt % tantalum, 0.0 to 9.0 wt % tungsten, 0.0 to 10 wt % molybdenum, 0.0 to 43.0 wt % platinum, and the balance nickel.
FILED	Monday, January 13, 2014
APPL NO	14/153130
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Alloys C22C 19/05 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/08 (20130101) Original (OR) Class C23C 4/073 (20160101) C23C 14/16 (20130101) C23C 28/021 (20130101) C23C 28/022 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/90 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12931 (20150115)
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09382960 — Beam-based nonlinear spring

US 09382960	Kluger et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Jocelyn Maxine Kluger (South Glastonbury, Connecticut); Alexander Henry Slocum (Bow, New Hampshire); Themistoklis Panagiotis Sapsis (Cambridge, Massachusetts)
ABSTRACT	Nonlinear spring. In one embodiment, the spring includes two opposed curved surfaces curving away from one another. A flexible cantilever member is disposed between the two opposed curved surfaces and a mass is attached to a free end of the cantilever member wherein the flexible cantilever member wraps around one of the curved surfaces as the cantilever member deflects to form a nonlinear spring. Energy harvesting devices and a load cell are also disclosed.
FILED	Friday, January 23, 2015
APPL NO	14/603492
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 1/00 (20130101) F03G 1/02 (20130101) F03G 1/10 (20130101) F03G 7/08 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 1/22 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/00 (20130101) G01L 1/044 (20130101) Dynamo-electric Machines H02K 7/1876 (20130101) H02K 35/02 (20130101)
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09383065 — Underwater cryogenic storage vessel and method of using the same

US 09383065	Cady et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Navy (DON)
APPLICANT(S)	The Boeing Company (Chicago, Illinois)
ASSIGNEE(S)	The Boeing Company (Chicago, Illinois)
INVENTOR(S)	Edwin C. Cady (Tustin, California); Daniel A. Watts (Surfside, California); Gary D. Grayson (Huntington Beach, California)
ABSTRACT	Technologies are described herein for storing fluid in an underwater cryogenic storage vessel designed for use in a fuel system of an underwater vehicle. According to one aspect of the disclosure, a storage vessel includes at least two concentrically arranged storage tanks, which includes a first storage tank and a second storage tank. The first storage tank surrounds the second storage tank, such that the first storage tank is configured to protect the second storage tank from external environmental conditions. The storage vessel also includes a storage compartment positioned adjacent to the two storage tanks. In one embodiment, the storage vessel may be an underwater cryogenic storage vessel that stores liquid oxygen used as a reactant in a fuel cell and liquid carbon dioxide, which is an effluent of the fuel cell.
FILED	Thursday, January 23, 2014
APPL NO	14/162188
ART UNIT	3744 — Printing/Measuring and Testing
CURRENT CPC	Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 3/10 (20130101) F17C 6/00 (20130101) F17C 13/082 (20130101) F17C 2205/0149 (20130101) F17C 2270/0131 (20130101) Pipe-line Systems; Pipe-lines F17D 3/01 (20130101) Original (OR) Class
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09383109 — Modular brick or block outdoor structures

US 09383109	Raboine
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Aberdeen Proving Ground (APG)
APPLICANT(S)	Oldcastle Building Products, Inc. (Atlanta, Georgia)
ASSIGNEE(S)	OLDCASTLE APG SOUTH, INC. (Atlanta, Georgia)
INVENTOR(S)	Joseph P. Raboine (Burlington, Wisconsin)
ABSTRACT	A modular brick or block outdoor structure includes an outdoor structure that is constructed in modular sections. Each modular section is fabricated from a plurality of paving bricks or retaining wall blocks that match the brick or block used to construct the patio. The bricks or blocks are preferably assembled to each other with adhesive. Each modular section includes means for transporting thereof with some type of equipment, if necessary. It is preferable that each modular section include channels to receive lifting forks of an end loader or other suitable transport device, if necessary. However, other methods of transporting the modular section may also be used.
FILED	Thursday, April 09, 2015
APPL NO	14/682867
ART UNIT	3633 — Static Structures, Supports and Furniture
CURRENT CPC	Kitchen Equipment; Coffee Mills; Spice Mills; Apparatus for Making Beverages A47J 37/0704 (20130101) A47J 37/0759 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/34336 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 1/1205 (20130101) Domestic Stoves or Ranges for Solid Fuels; Implements for Use in Connection With Stoves or Ranges F24B 1/181 (20130101) Original (OR) Class F24B 1/182 (20130101) F24B 1/191 (20130101)
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09383172 — Interleaving angled hexagonal tile for flexible armor

US 09383172	Gamache et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Raymond M. Gamache (Indian Head, Maryland); Justin T. Blair (Woodford, Virginia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Raymond M. Gamache (Indian Head, Maryland); Justin T. Blair (Woodford, Virginia)
ABSTRACT	An interleaving hexagonal tile (AHT) is provided for incorporation onto a liner in an array for a personnel armor clothing article. The AHT includes a hexagonally-symmetric solid object composed of a homogeneous material. The object includes a geometry that has obverse and reverse planar surfaces parallel to each other. Each planar surface has triangularly disposed terminals. First and second triple sets of oblique surfaces are disposed between the obverse and reverse planar surfaces. A plurality of facets is disposed substantially perpendicular to the planar surfaces. The facets connect between edges of the planar surfaces and adjacent edges of the oblique surfaces. The first and second triple sets of oblique surfaces are disposed to alternate with each other.
FILED	Friday, January 23, 2015
APPL NO	14/604644
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/02 (20130101) Original (OR) Class
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09383173 — Transparent armor construction

US 09383173	Gilde et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	U.S. Army Research Laboratory ATTN: RDRL-LOC-I (Adelphi, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Gary A. Gilde (North East, Maryland); Parimal J. Patel (Joppa, Maryland); Terrence M. Taylor (Aberdeen, Maryland); David M. Spagnuolo (Newark, Delaware); Constantine Fountzoulas (Wilmington, Delaware)
ABSTRACT	A transparent armor construction having a laminate structure with at least two layers. The layers are constructed of two different materials selected from the group of glass, ceramic, resin, polymeric material, and plastic and in which the at least two layers include different coefficients of thermal expansion. The layers are bonded together and a planar frame having an open central section and an outer border is then bonded to the laminate structure. The material for the planar frame is selected so that it has a coefficient of thermal expansion less than the coefficient of thermal expansion of the laminate layer to which it is bonded.
FILED	Monday, July 22, 2013
APPL NO	13/947690
ART UNIT	1781 — Miscellaneous Articles, Stock Material
CURRENT CPC	Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/08 (20130101) B32B 3/266 (20130101) B32B 7/02 (20130101) B32B 7/12 (20130101) B32B 17/10 (20130101) B32B 17/064 (20130101) B32B 17/101 (20130101) B32B 17/1077 (20130101) B32B 17/10119 (20130101) B32B 17/10293 (20130101) B32B 17/10366 (20130101) B32B 17/10752 (20130101) B32B 17/10761 (20130101) B32B 2307/30 (20130101) B32B 2307/50 (20130101) B32B 2307/412 (20130101) B32B 2307/558 (20130101) B32B 2605/00 (20130101) B32B 2605/006 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0407 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 428/911 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/162 (20150115) Y10T 428/166 (20150115) Y10T 428/24298 (20150115) Y10T 428/24322 (20150115) Y10T 428/24331 (20150115) Y10T 428/24752 (20150115) Y10T 428/24777 (20150115) Y10T 428/24942 (20150115) Y10T 428/31522 (20150401) Y10T 428/31601 (20150401)
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09383180 — Gravity dropped small weapon electronic safe arm fuze and energy harvesting device for power generation onboard gravity dropped weapons

US 09383180	Rastegar et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC)
APPLICANT(S)	Jahangir S Rastegar (Stony Brook, New York); Richard T Murray (Patchogue, New York)
ASSIGNEE(S)	OMNITEK PARTNERS LLC (Ronkonkoma, New York)
INVENTOR(S)	Jahangir S Rastegar (Stony Brook, New York); Richard T Murray (Patchogue, New York)
ABSTRACT	A generator including: a member having a cable wound thereon, the cable having a free end; a spring for storing energy as the cable is unwound from the member by pulling on the free end; and an electromagnetic generator operatively connected to the member such that rotation of the member is transferred to an input side of the electromagnetic generator after the cable is unwound from the member and the stored energy in the spring turns the member.
FILED	Tuesday, March 12, 2013
APPL NO	13/797938
ART UNIT	2831 — Electrical Circuits and Systems
CURRENT CPC	Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/008 (20130101) Original (OR) Class F42C 15/40 (20130101) Dynamo-electric Machines H02K 7/1807 (20130101) H02K 7/1853 (20130101) Electric Machines Not Otherwise Provided for H02N 2/18 (20130101)
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09383292 — Flexible fiber-based micro and nanofluidics for probing liquids

US 09383292	Kornev et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Konstantin G. Kornev (Clemson, South Carolina); Chen-Chih Tsai (New Taipei, Taiwan); David Lukas (Rochlice, Czech Republic); Petr Mikes (Liberce, Czech Republic)
ASSIGNEE(S)	CLEMSON UNIVERSITY (Clemson, South Carolina)
INVENTOR(S)	Konstantin G. Kornev (Clemson, South Carolina); Chen-Chih Tsai (New Taipei, Taiwan); David Lukas (Rochlice, Czech Republic); Petr Mikes (Liberce, Czech Republic)
ABSTRACT	A fluidic probe comprising a plurality of oriented fibers with individual fibers having nano-pores in the fiber bodies, the oriented fibers being twisted together, wherein the twisted oriented fibers form micro-pores between the individual fibers, is disclosed. The fluidic probe exhibits excellent flexibility, deployability and absorptive capacity. The enhanced absorptive capacity is due to the fluid absorption via capillary action of the nano-pores and fluid transport via the micro-pores. The probes can also be formed so as to be remotely controlled by electromagnetic fields and thus be used in a hands-free fashion. With these probes, the paradigm of a stationary microfluidic platform can be shifted to include flexible structures that can include multiple microfluidic sensors in a single fibrous probe.
FILED	Wednesday, September 12, 2012
APPL NO	13/611971
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Separation B01D 2239/025 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) Original (OR) Class
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09383337 — Method and apparatus for analysis and sorting of polynucleotides based on size

US 09383337	Quake et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	California Institute of Technology (Pasadena, California)
ASSIGNEE(S)	California Institute of Technology (Pasadena, California)
INVENTOR(S)	Stephen R. Quake (Stanford, California); Wayne D. Volksmuth (Menlo Park, California)
ABSTRACT	The invention relates to a microfabricated device and methods of using the device for analyzing and sorting polynucleotide molecules by size.
FILED	Monday, January 14, 2013
APPL NO	13/741249
ART UNIT	1759 — Optics
CURRENT CPC	Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/0415 (20130101) B01L 2400/0421 (20130101) B01L 2400/0484 (20130101) B01L 2400/0487 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44791 (20130101) Original (OR) Class G01N 2015/149 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 366/03 (20130101)
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09383350 — Engineered cell growth on polymeric films and biotechnological application thereof

US 09383350	Parker et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	Kevin Kit Parker (Cambridge, Massachusetts); Adam W. Feinberg (Pittsburgh, Pennsylvania); George M. Whitesides (Netwon, Massachusetts); Sergey S. Shevkoplyas (New Orleans, Louisiana); Alexander Feigel (Petah-Tikva, Illinois)
ABSTRACT	A free-standing thin film is fabricated from a structure comprising a base layer coated with a sacrificial polymer layer, which is in turn coated with a flexible polymer layer. Cells are then seeded onto the flexible polymer layer and cultured to form a tissue. The flexible polymer layer is then released from the base layer to produce a free-standing thin film comprising the tissue on the flexible polymer layer. In one embodiment, the cells are myocytes, which can be actuated to propel or displace the free-standing film. In another embodiment, the free-standing film is used to treat injured human tissue.
FILED	Thursday, June 20, 2013
APPL NO	13/922432
ART UNIT	1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0657 (20130101) C12N 2533/30 (20130101) C12N 2533/52 (20130101) C12N 2539/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5061 (20130101) Original (OR) Class G01N 2500/10 (20130101)
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09383353 — Fluorescent methods and materials for directed biomarker signal amplification

US 09383353	Gaylord et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Army Research Office (CCDC ARO)
APPLICANT(S)	Sirigen Inc. (San Diego, California)
ASSIGNEE(S)	Sirigen Inc. (La Jolla, California)
INVENTOR(S)	Brent S. Gaylord (Santa Barbara, California); Janice W. Hong (Santa Barbara, California); Tsu-Ju Fu (Poway, California); ChengJun Sun (Goleta, California); Russell Baldocchi (Santa Barbara, California)
ABSTRACT	Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
FILED	Tuesday, June 17, 2014
APPL NO	14/307258
ART UNIT	1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 2261/3142 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class G01N 33/582 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0039 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/13 (20150115)
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09383478 — System and method for atmospheric parameter enhancement

US 09383478	Miller
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	Steven D. Miller (Fort Collins, Colorado)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Steven D. Miller (Fort Collins, Colorado)
ABSTRACT	System and method for enhancing at least one atmospheric parameter of interest provided in remotely-sensed data by detecting and suppressing false alarm data, including computer code to receive measurement data and background including false alarms, computer code to conduct detection tests for the atmospheric parameter, computer code to compute the strength of the tests, and computer code to weight the measurement data based on the strengths and enhance the measurement data based on the weighted data.
FILED	Wednesday, January 08, 2014
APPL NO	14/150467
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Meteorology G01W 1/00 (20130101) G01W 1/18 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 2207/10032 (20130101) G06T 2207/30192 (20130101)
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09383561 — Compact annular field imager and method for imaging electromagnetic radiation

US 09383561	Mitchell
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Thomas A. Mitchell (Nazareth, Pennsylvania)
ASSIGNEE(S)	Wavefront Research, Inc. (Bethlehem, Pennsylvania)
INVENTOR(S)	Thomas A. Mitchell (Nazareth, Pennsylvania)
ABSTRACT	The present disclosure provides an optical imager and a method for imaging electromagnetic radiation. In one aspect, the optical imager includes an object array substantially located at an object plane, a first catadioptric element configured to substantially collimate, at a central plane, electromagnetic radiation emanating from the object array, a second catadioptric element configured to image the substantially collimated electromagnetic radiation from the central plane onto an image plane, and a detecting element substantially located at the image plane. The first catadioptric element includes at least one refractive surface and at least one reflective surface, and the second catadioptric element includes at least one refractive surface and at least one reflective surface.
FILED	Friday, March 14, 2014
APPL NO	14/212917
ART UNIT	2878 — Optics
CURRENT CPC	Optical Elements, Systems, or Apparatus G02B 17/08 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14629 (20130101)
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09383968 — Math processing by detection of elementary valued operands

US 09383968	Finchelstein et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE)
APPLICANT(S)	NVIDIA CORPORATION (Santa Clara, California)
ASSIGNEE(S)	NVIDIA Corporation (Santa Clara, California)
INVENTOR(S)	Daniel Finchelstein (Redwood City, California); David Conrad Tannenbaum (Austin, Texas); Srinivasan (Vasu) Iyer (Austin, Texas)
ABSTRACT	One embodiment of the present invention includes a method for simplifying arithmetic operations by detecting operands with elementary values such as zero or 1.0. Computer and graphics processing systems perform a great number of multiply-add operations. In a significant portion of these operations, the values of one or more of the operands are zero or 1.0. By detecting the occurrence of these elementary values, math operations can be greatly simplified, for example by eliminating multiply operations when one multiplicand is zero or 1.0 or eliminating add operations when one addend is zero. The simplified math operations resulting from detecting elementary valued operands provide significant savings in overhead power, dynamic processing power, and cycle time.
FILED	Friday, September 27, 2013
APPL NO	14/040370
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 7/50 (20130101) Original (OR) Class G06F 7/5443 (20130101) G06F 2207/3884 (20130101)
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09384042 — Techniques for dynamically assigning jobs to processors in a cluster based on inter-thread communications

US 09384042	Arimilli et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	Lakshminarayana Baba Arimilli (Austin, Texas); Ravi Kumar Arimilli (Austin, Texas); Claude Basso (Raleigh, North Carolina); Jean L. Calvignac (Raleigh, North Carolina)
ASSIGNEE(S)	International Business Machines Corporation (Armonk, New York)
INVENTOR(S)	Lakshminarayana Baba Arimilli (Austin, Texas); Ravi Kumar Arimilli (Austin, Texas); Claude Basso (Raleigh, North Carolina); Jean L. Calvignac (Raleigh, North Carolina)
ABSTRACT	A technique for operating a high performance computing (HPC) cluster includes monitoring communication between threads assigned to multiple processors included in the HPC cluster. The HPC cluster includes multiple nodes that each include two or more of the multiple processors. One or more of the threads are moved to a different one of the multiple processors based on the communication between the threads.
FILED	Tuesday, December 16, 2008
APPL NO	12/336302
ART UNIT	2195 — Interprocess Communication and Software Development
CURRENT CPC	Electric Digital Data Processing G06F 9/4856 (20130101) Original (OR) Class G06F 9/5066 (20130101) G06F 9/5088 (20130101)
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09384320 — Methods of storing information using nucleic acids

US 09384320	Church
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR)
APPLICANT(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S)	President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S)	George M. Church (Brookline, Massachusetts)
ABSTRACT	The present invention relates to methods of storing data using one or more nucleic acids including converting a format of information into a plurality of bit sequences of a bit stream with each having a corresponding bit barcode, converting the plurality of bit sequences to a plurality of corresponding oligonucleotide sequences using one bit per base encoding, synthesizing the plurality of corresponding oligonucleotide sequences, and storing the synthesized plurality of corresponding oligonucleotide sequences.
FILED	Wednesday, July 17, 2013
APPL NO	14/415014
ART UNIT	2876 — Optics
CURRENT CPC	Electric Digital Data Processing G06F 19/22 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/00 (20130101)
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09384447 — Passive tracking of underwater acoustic sources with sparse innovations

US 09384447	Forero et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON)
APPLICANT(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S)	Pedro A. Forero (San Diego, California); Paul A. Baxley (San Diego, California)
ABSTRACT	A system and method involve acoustic source localization using passive sonar and capitalizing on the sparse nature of a source location map (SLM). Two types of sparsity are exploited, namely sparsity in the support of the SLMs and sparsity in the innovations across consecutive SLMs. The first type is motivated by the desire to construct SLMs whose non-zero entries corresponded to locations where sources are present. The second type of sparsity is motivated by the observation that few changes occur in the support of consecutive SLMs. Per time instant, an SLM is obtained as the solution of a regularized least-squares problem, where the regularization terms are chosen to encourage the desired sparse structures in each SLM and the innovations. Each SLM may be obtained via a specifically-tailored, computationally-efficient proximal gradient algorithm.
FILED	Monday, December 07, 2015
APPL NO	14/961705
ART UNIT	2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/18 (20130101) Electric Digital Data Processing G06F 17/14 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) Original (OR) Class Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) H04R 1/406 (20130101) H04R 3/005 (20130101) H04R 29/005 (20130101)
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09384677 — Automated execution and evaluation of network-based training exercises

US 09384677	Brueckner et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S)	Architecture Technology Corporation (Minneapolis, Minnesota)
INVENTOR(S)	Stephen K. Brueckner (Ithaca, New York); Frank N. Adelstein (Ithaca, New York); Haim Yehuda Bar (Ithaca, New York); Matthew P. Donovan (Trumansburg, New York)
ABSTRACT	This disclosure generally relates to automated execution and evaluation of computer network training exercises, such as in a virtual machine environment. An example environment includes a control and monitoring system, an attack system, and a target system. The control and monitoring system initiates a training scenario to cause the attack system to engage in an attack against the target system. The target system then performs an action in response to the attack. Monitor information associated with the attack against the target system is collected by continuously monitoring the training scenario. The attack system is then capable of sending dynamic response data to the target system, wherein the dynamic response data is generated according to the collected monitor information to adapt the training scenario to the action performed by the target system. The control and monitoring system then generates an automated evaluation based upon the collected monitor information.
FILED	Friday, April 10, 2015
APPL NO	14/683923
ART UNIT	3715 — Amusement and Education Devices
CURRENT CPC	Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/00 (20130101) G09B 7/00 (20130101) G09B 9/00 (20130101) G09B 19/003 (20130101) G09B 19/0053 (20130101) Original (OR) Class
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09384905 — High performance transition metal carbide and nitride and boride based asymmetric supercapacitors

US 09384905	Thompson et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)	Levi T. Thompson (Northville, Michigan); Paul Rasmussen (Ann Arbor, Michigan); Saemin Choi (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan, University of Michigan Office of Technology Transfer (Ann Arbor, Michigan)
INVENTOR(S)	Levi T. Thompson (Northville, Michigan); Paul Rasmussen (Ann Arbor, Michigan); Saemin Choi (Ann Arbor, Michigan)
ABSTRACT	In accordance with an embodiment of the disclosure, an asymmetric supercapacitor includes a first active material with a high hydrogen over-potential and a second active material with a high oxygen over-potential. The first active material is based on a nitride, an oxynitride, a carbide, an oxycarbide, a boride, or an oxyboride of a metal selected from Groups III, IV, V, VI, and VII of the Periodic Table.
FILED	Wednesday, October 12, 2011
APPL NO	13/272185
ART UNIT	2848 — Electrical Circuits and Systems
CURRENT CPC	Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/04 (20130101) H01G 11/46 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7022 (20130101)
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09385083 — Wafer-level die to package and die to die interconnects suspended over integrated heat sinks

US 09385083	Herrault et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S)	HRL Laboratories, LLC (Malibu, California)
INVENTOR(S)	Florian G. Herrault (Agoura Hills, California); Melanie S. Yajima (Los Angeles, California); Alexandros Margomenos (San Jose, California); Miroslav Micovic (Thousand Oaks, California)
ABSTRACT	An interconnect for electrically coupling pads formed on adjacent chips or on packaging material adjacent the chips, with an electrically conductive heat sink being disposed between the pads, the interconnect comprising a metallic membrane layer disposed between two adjacent pads and disposed or bridging over the electrically conductive heat sink so as to avoid making electrical contact with the electrically conductive heat sink. An electroplated metallic layer is disposed on the metallic membrane layer. Fabrication of interconnect permits multiple interconnects to be formed in parallel using fabrication techniques compatible with wafer level fabrication of the interconnects. The interconnects preferably follow a smooth curve to electrically connect adjacent pads and following that smooth curve they bridge over the intervening electrically conductive heat sink material in a predictable fashion.
FILED	Friday, May 22, 2015
APPL NO	14/720619
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76816 (20130101) H01L 21/76829 (20130101) H01L 21/76873 (20130101) H01L 21/76877 (20130101) H01L 23/36 (20130101) H01L 23/528 (20130101) Original (OR) Class H01L 23/53247 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20154 (20130101)
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09385159 — Electronic circuitry having superconducting tunnel junctions with functional electromagnetic-responsive tunneling regions

US 09385159	Taylor
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Sercretary of the Navy (Washington, District of Columbia)
INVENTOR(S)	Benjamin J. Taylor (San Diego, California)
ABSTRACT	A device includes at least one superconducting tunnel junction having a junction region comprising a junction barrier material responsive to electromagnetic fields within the MHz to THz range. The junction may be contained within a bi-SQUID loop having two main junctions and a center junction. The junction barrier material for the main junctions may have different electromagnetic-responsive properties than the junction barrier material for the center junction. The junction barrier material may include type-I multiferroics, type-II multiferroics, a composite multiferroic including layers of magnets and ferroelectrics, or piezoelectric materials. An array of connected bi-SQUID loops may be formed, where the main junctions of each bi-SQUID loop in each row are connected. The electromagnetic-responsive properties of the junction barrier material for center junctions of each bi-SQUID loop may vary by each array column or row. The center/main junctions of each bi-SQUID loop may be connected to an input signal line.
FILED	Monday, June 30, 2014
APPL NO	14/319112
ART UNIT	2818 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) Original (OR) Class H01L 39/025 (20130101) H01L 39/126 (20130101) H01L 39/225 (20130101)
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09385271 — Device with transparent and higher conductive regions in lateral cross section of semiconductor layer

US 09385271	Shur et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
ASSIGNEE(S)	Sensor Electronic Technology, Inc. (Columbia, South Carolina)
INVENTOR(S)	Michael Shur (Latham, New York); Maxim S. Shatalov (Columbia, South Carolina); Alexander Dobrinsky (Loudonville, New York); Remigijus Gaska (Columbia, South Carolina); Jinwei Yang (Columbia, South Carolina)
ABSTRACT	A device including one or more layers with lateral regions configured to facilitate the transmission of radiation through the layer and lateral regions configured to facilitate current flow through the layer is provided. The layer can comprise a short period superlattice, which includes barriers alternating with wells. In this case, the barriers can include both transparent regions, which are configured to reduce an amount of radiation that is absorbed in the layer, and higher conductive regions, which are configured to keep the voltage drop across the layer within a desired range.
FILED	Tuesday, May 26, 2015
APPL NO	14/721082
ART UNIT	2828 — Semiconductors/Memory
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02458 (20130101) H01L 21/02507 (20130101) H01L 29/15 (20130101) H01L 29/778 (20130101) H01L 29/2003 (20130101) H01L 33/06 (20130101) Original (OR) Class H01L 33/0025 (20130101) H01L 33/32 (20130101)
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09385293 — Quantum memory device and method

US 09385293	Nayfeh et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)	The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
ASSIGNEE(S)	THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (Washington, District of Columbia)
INVENTOR(S)	Osama Nayfeh (San Diego, California); Anna Leese De Escobar (San Diego, California); Kenneth Simonsen (San Diego, California)
ABSTRACT	A system and method involve generating an electric field across a superconductor device having an ionic layer disposed between and separated from first and second superconductor layers by respective first and second barrier layers. The electric field may be generated by applying an input signal, such as a voltage, to the superconductor device while the device is in a superconducting state. The voltage may be below a threshold voltage for inducing ion transport within the ionic layer or may be above or below a threshold voltage for inducing ion transport from the ionic layer across an ionic layer/barrier layer interface. The ion transport may tune the potential profile and/or modulate the critical current of the superconductor device and may include quantum coherent ionic transport, Josephson tunneling, or resonant tunneling. The electric field generated across the superconductor device may alter the spin-states of the ions within the ionic layer.
FILED	Tuesday, May 19, 2015
APPL NO	14/716629
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 39/221 (20130101) Original (OR) Class H01L 39/223 (20130101)
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09385306 — Ferroelectric mechanical memory and method

US 09385306	Fox et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL)
APPLICANT(S)	U.S. Army Research Laboratory (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Glen R Fox (Colorado Springs, Colorado); Jeffrey S. Pulskamp (Fulton, Maryland); Ronald G. Polcawich (Derwood, Maryland)
ABSTRACT	A memory device comprising a base; a capacitor comprising a ferroelectric layer and at least two electrically conductive layers, the ferroelectric layer being located between the at least two electrically conductive layers; each of the at least two conductive layers being operatively connected to a current source; a cantilever attached to the base at first end and movable at a second end, the ferroelectric capacitor being mounted to the cantilever such that the second end of the cantilever moves a predetermined displacement upon application of a current to the ferroelectric layer which induces deformation of the ferroelectric layer thereby causing displacement of the cantilever which is operatively associated with a contact so that an electrical connection is enabled with the contact upon the predetermined displacement of the cantilever. The presence or absence of a connection forms two states of a memory cell.
FILED	Thursday, March 12, 2015
APPL NO	14/645711
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) H01L 43/08 (20130101) Original (OR) Class H01L 43/10 (20130101) H01L 43/12 (20130101)
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09385332 — Organic-inorganic hybrid multilayer gate dielectrics for thin film transistors

US 09385332	Marks et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Tobin J. Marks (Evanston, Illinois); Young-geun Ha (Evanston, Illinois); Antonio Facchetti (Chicago, Illinois)
ABSTRACT	Disclosed are organic-inorganic hybrid self-assembled multilayers that can be used as electrically insulating (or dielectric) materials. These multilayers generally include an inorganic primer layer and one or more bilayers deposited thereon. Each bilayer includes a chromophore or “π-polarizable” layer and an inorganic capping layer composed of zirconia. Because of the regularity of the bilayer structure and the aligned orientation of the chromophore resulting from the self-assembly process, the present multilayers have applications in electronic devices such as thin film transistors, as well as in nonlinear optics and nonvolatile memories.
FILED	Tuesday, September 08, 2015
APPL NO	14/848281
ART UNIT	2898 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/441 (20130101) H01L 29/24 (20130101) H01L 29/513 (20130101) H01L 29/517 (20130101) H01L 29/4908 (20130101) H01L 29/66969 (20130101) H01L 51/0529 (20130101) H01L 51/0533 (20130101) Original (OR) Class H01L 51/0537 (20130101) H01L 51/0545 (20130101) H01L 2251/301 (20130101)
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09385348 — Organic electronic devices with multiple solution-processed layers

US 09385348	Forrest et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Stephen R. Forrest (Ann Arbor, Michigan); Brian E. Lassiter (San Francisco, California); Jeramy D. Zimmerman (Golden, Colorado)
ABSTRACT	A method for fabricating an organic light emitting device stack involves depositing a first conductive electrode layer over a substrate; depositing a first set of one or more organic layers, wherein at least one of the first set of organic layers is a first emissive layer and one of the first set of organic layers is deposited by a solution-based process that utilizes a first solvent; depositing a first conductive interlayer by a dry deposition process; and depositing a second set of one or more organic layers, wherein at least one of the second set of organic layers is a second emissive layer and one of the second set of organic layers is deposited by a solution-based process that utilizes a second solvent, wherein all layers that precede the layer deposited using the second solvent are insoluble in the second solvent.
FILED	Tuesday, August 04, 2015
APPL NO	14/817979
ART UNIT	2829 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/302 (20130101) H01L 51/001 (20130101) H01L 51/0003 (20130101) H01L 51/0007 (20130101) H01L 51/0021 (20130101) H01L 51/0026 (20130101) H01L 51/0028 (20130101) H01L 51/0047 (20130101) H01L 51/56 (20130101) Original (OR) Class H01L 51/424 (20130101) H01L 51/504 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5088 (20130101) H01L 51/5092 (20130101) H01L 51/5096 (20130101) H01L 51/5206 (20130101) H01L 51/5221 (20130101) H01L 51/5278 (20130101)
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09385448 — Electrical connection via fastener hole

US 09385448	Bondurant et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Quest Integrated, Inc. (Kent, Washington)
ASSIGNEE(S)	Quest Integrated, LLC (Kent, Washington)
INVENTOR(S)	Phillip D. Bondurant (Covington, Washington); Giovanni Nino (Issaquah, Washington); David W. Rook (Kent, Washington); Anthony Mactutis (Auburn, Washington); David Bothell (Lake Tapps, Washington)
ABSTRACT	The systems, apparatus, and methods disclosed herein provide access to systems located within a closed structure, such that the systems are traditionally difficult for humans to access. Exemplary structures include an engine compartment, airplane wing, or fuselage. This access allows a system located within the structure to be electrically coupled with an electrical I/O device located outside the structure. Access to a system located within the closed structure is provided by way of a hole.
FILED	Wednesday, July 31, 2013
APPL NO	13/956331
ART UNIT	2867 — Printing/Measuring and Testing
CURRENT CPC	Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 2001/0064 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/00 (20130101) G01N 17/04 (20130101) G01N 29/223 (20130101) G01N 2201/00 (20130101) G01N 2203/00 (20130101) G01N 2291/0289 (20130101) G01N 2291/2691 (20130101) G01N 2291/2694 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 1/0416 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 11/00 (20130101) Original (OR) Class
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09385654 — High-precision GHZ clock generation using spin states in diamond

US 09385654	Englund et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR)
APPLICANT(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S)	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S)	Dirk R. Englund (New York, New York); Jonathan Hodges (Princeton, New Jersey); Mikhail D. Lukin (Cambridge, Massachusetts); Norman Y. Yao (Basking Ridge, New Jersey)
ABSTRACT	Techniques for obtaining a frequency standard using the crystal field splitting frequency of nitrogen vacancy center in diamond are disclosed. In certain exemplary embodiments, a microwave field is applied to the diamond and optically exciting the diamond under green light. The photoluminescent response of the diamond is measured by a photodetector. The intensity of the photoluminescent response can be used to determine the phase shift between the microwave and the crystal field splitting frequency. The microwave field frequency can be adjusted until the phase shift is below a predetermined threshold, and the microwave frequency can then be output for use as a standard.
FILED	Thursday, March 13, 2014
APPL NO	14/208198
ART UNIT	2868 — Printing/Measuring and Testing
CURRENT CPC	Measuring Electric Variables; Measuring Magnetic Variables G01R 33/1284 (20130101) Time-interval Measuring G04F 5/14 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 17/00 (20130101) Original (OR) Class Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/00 (20130101) H03L 7/26 (20130101)
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09385657 — Triple balanced, interleaved mixer

US 09385657	Daftari et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S)	Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S)	Naveen Daftari (Redondo Beach, California); Tim LaRocca (Redondo Beach, California)
ABSTRACT	A triple-balanced mixer is disclosed. The mixer features a complementary metal oxide semiconductor (CMOS) mmW (millimeter wave) integrated circuit and adds an inverted double balanced mixer to a double-balanced Gilbert cell mixer to provide a triple-balanced mixer. Another term for this type of mixer is doubly double balanced. Pairs of field effect transistor (FET) devices are interleaved into a single device. The inverted mixer provides an inverted LO feedthrough signal equal in amplitude to the LO feedthrough from the first mixer. The inverted LO feedthrough is used to cancel the LO feedthrough, or leakage, of the first mixer at the RF port.
FILED	Tuesday, March 31, 2015
APPL NO	14/674379
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Demodulation or Transference of Modulation From One Carrier to Another H03D 7/14 (20130101) H03D 7/1441 (20130101) H03D 7/1458 (20130101) Original (OR) Class H03D 7/1466 (20130101)
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09385722 — Voltage level shifter circuit

US 09385722	Trivedi et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Intel Corporation (Santa Clara, California)
ASSIGNEE(S)	Intel Corporation (Santa Clara, California)
INVENTOR(S)	Amit R. Trivedi (Atlanta, Georgia); Jaydeep P. Kulkarni (Hillsboro, Oregon); Carlos Tokunaga (Hillsboro, Oregon); Muhammad M. Khellah (Tigard, Oregon); James W. Tschanz (Portland, Oregon)
ABSTRACT	Embodiments include apparatuses, methods, and systems for voltage level shifting a data signal between a low voltage domain and a high voltage domain. In embodiments, a voltage level shifter circuit may include adaptive keeper circuitry, enhanced interruptible supply circuitry, and/or capacitive boosting circuitry to reduce a minimum voltage of the low voltage domain that is supported by the voltage level shifter circuit. Other embodiments may be described and claimed.
FILED	Tuesday, November 25, 2014
APPL NO	14/553934
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 19/018521 (20130101) Original (OR) Class
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09385738 — Digital readout method and apparatus

US 09385738	Kelly et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) National Geospatial Intelligence Agency (NGA)
APPLICANT(S)	Michael Kelly (North Reading, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexington, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Michael Kelly (North Reading, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexington, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ABSTRACT	Autonomously operating analog to digital converters are formed into a two dimensional array. The array may incorporate digital signal processing functionality. Such an array is particularly well-suited for operation as a readout integrated circuit and, in combination with a sensor array, forms a digital focal plane array.
FILED	Monday, December 08, 2014
APPL NO	14/563271
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 1/60 (20130101) H03M 1/145 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/3355 (20130101) H04N 5/37455 (20130101)
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09385891 — Galvanic isolation interface for high-speed data link for spacecraft electronics, and method of using same

US 09385891	Boggan
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) The Aerospace Corporation (AEROSPACE) Federally Funded Research and Development Center (FFRDC) Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)	The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S)	The Aerospace Corporation (El Segundo, California)
INVENTOR(S)	Garry H. Boggan (League City, Texas)
ABSTRACT	Under one aspect of the present invention, a structure for providing galvanically isolated communication between first and second spacecraft electronic components includes a semi-insulating substrate; an input port disposed on the substrate and configured to receive a signal from the first spacecraft electronic component; a coupling structure disposed on the substrate, coupled to the input port so as to receive the signal, and configured to provide an isolated replica of the received signal as an output; a signal conditioner disposed on the substrate, coupled to the coupling structure so as to receive the isolated replica of the received signal, and configured to condition the isolated replica; and an output port disposed on the substrate, coupled to the signal conditioner so as to receive the conditioned isolated replica, and configured to provide the conditioned isolated replica to the second spacecraft electronic component.
FILED	Thursday, August 13, 2015
APPL NO	14/825586
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/081 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0266 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49117 (20150115)
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09385936 — Forwarding groups of multicast flows

US 09385936	Bisdikian
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF)
APPLICANT(S)	Chatschik Bisdikian (Chappaqua, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Chatschik Bisdikian (Chappaqua, New York)
ABSTRACT	A routing element and method for forwarding multicast traffic in a network includes grouping a collection of path-related multicast information flows from a source and associating each information flow of the collection with a multicast address from a set of multicast addresses. Forwarding information is placed in routers within the network between the sources and destinations wherein the forwarding information includes a single entry in a forwarding table using an identifier, e.g., a representative address, for the collection.
FILED	Wednesday, June 13, 2012
APPL NO	13/495711
ART UNIT	2414 — Multiplex and VoIP
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 12/1854 (20130101) H04L 45/00 (20130101) Original (OR) Class H04L 45/16 (20130101) H04L 45/54 (20130101) H04L 45/306 (20130101)
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09386674 — Mechanoluminescent X-ray generator

US 09386674	Putterman et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Seth J. Putterman (Malibu, California); Carlos Camara (Venice, California); Juan V. Escobar (Venice, California); Jonathan Hird (Cambridge, United Kingdom)
ABSTRACT	A device for generating x-rays has an enclosing vessel having a structure suitable to provide an enclosed space at a predetermined fluid pressure, wherein the enclosing vessel has a window portion and a shielding portion in which the shielding portion is more optically dense to x-rays than the window portion; a mechanoluminescent component disposed at least partially within the enclosing vessel; and a mechanical assembly connected to the mechanoluminescent component. The mechanical assembly provides mechanical energy to the mechanoluminescent component while in operation, and at least some of the mechanical energy when provided to the mechanoluminescent component by the mechanical assembly is converted to x-rays.
FILED	Friday, January 10, 2014
APPL NO	14/152770
ART UNIT	2884 — Optics
CURRENT CPC	X-ray Technique H05G 2/00 (20130101) Original (OR) Class
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09386676 — Apparatus for magnetic and electrostatic confinement of plasma

US 09386676	Rostoker et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Norman Rostoker (Irvine, California); Michl Binderbauer (Irvine, California)
ABSTRACT	An apparatus and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy well, created by tuning an externally applied magnetic field. The simultaneous electrostatic confinement of electrons and magnetic confinement of ions avoids anomalous transport and facilitates classical containment of both electrons and ions. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions ions are fused together by nuclear force, thus releasing fusion energy. Moreover, the fusion fuel plasmas that can be used with the present confinement system and method are not limited to neutronic fuels only, but also advantageously include advanced fuels.
FILED	Tuesday, June 11, 2013
APPL NO	13/915521
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Fusion Reactors G21B 1/052 (20130101) Nuclear Power Plant G21D 7/00 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/03 (20130101) H05H 1/14 (20130101) H05H 1/16 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/122 (20130101)
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D0760858 — Buttstock

US D760858	Formanes et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA)
APPLICANT(S)	Thomas J. Formanes (Ledgewood, New Jersey); Dennis M. Sheehan (Hoboken, New Jersey); Lucien G. Ingrassia (Hopatcong, New Jersey); Thomas C. Grego (Chester, New Jersey); Patrick W. Sherwood (Philadelphia, New York); Kevin T. Bauer (Lakeville, Pennsylvania); Joe O'Neil (Sparta, New Jersey); Steve Kotefski (Bloomingdale, New Jersey)
ASSIGNEE(S)	The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S)	Thomas J. Formanes (Ledgewood, New Jersey); Dennis M. Sheehan (Hoboken, New Jersey); Lucien G. Ingrassia (Hopatcong, New Jersey); Thomas C. Grego (Chester, New Jersey); Patrick W. Sherwood (Philadelphia, New York); Kevin T. Bauer (Lakeville, Pennsylvania); Joe O'Neil (Sparta, New Jersey); Steve Kotefski (Bloomingdale, New Jersey)
ABSTRACT
FILED	Tuesday, February 25, 2014
APPL NO	29/483065
ART UNIT	2914 — Design
CURRENT CPC	Arms, pyrotechnics, hunting and fishing equipment D22/108
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Department of Energy (DOE)

09382167 — Layered reactive particles with controlled geometries, energies, and reactivities, and methods for making the same

US 09382167	Fritz et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Gregory M. Fritz (Yorktown Heights, New York); Timothy P. Weihs (Baltimore, Maryland); Justin A. Grzyb (Greensboro, North Carolina)
ABSTRACT	An energetic composite having a plurality of reactive particles each having a reactive multilayer construction formed by successively depositing reactive layers on a rod-shaped substrate having a longitudinal axis, dividing the reactive-layer-deposited rod-shaped substrate into a plurality of substantially uniform longitudinal segments, and removing the rod-shaped substrate from the longitudinal segments, so that the reactive particles have a controlled, substantially uniform, cylindrically curved or otherwise rod-contoured geometry which facilitates handling and improves its packing fraction, while the reactant multilayer construction controls the stability, reactivity and energy density of the energetic composite.
FILED	Monday, March 25, 2013
APPL NO	13/850064
ART UNIT	1756 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/08 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 21/0083 (20130101) Original (OR) Class C06B 43/00 (20130101) C06B 45/14 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) C23C 16/01 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/25 (20150115) Y10T 428/131 (20150115) Y10T 428/2975 (20150115)
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09382185 — Processes for converting biomass-derived feedstocks to chemicals and liquid fuels

US 09382185	Held et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Virent, Inc (Madison, Wisconsin)
ASSIGNEE(S)	Virent, Inc. (Madison, Wisconsin)
INVENTOR(S)	Andrew Held (Madison, Wisconsin); Elizabeth Woods (Middleton, Wisconsin); Randy Cortright (Madison, Wisconsin); Matthew Gray (Highlands Ranch, Colorado)
ABSTRACT	The present invention provides processes, methods, and systems for converting biomass-derived feedstocks to liquid fuels and chemicals. The method generally includes the reaction of a hydrolysate from a biomass deconstruction process with hydrogen and a catalyst to produce a reaction product comprising one of more oxygenated compounds. The process also includes reacting the reaction product with a condensation catalyst to produce C₄₊compounds useful as fuels and chemicals.
FILED	Monday, March 17, 2014
APPL NO	14/215283
ART UNIT	1671 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 29/132 (20130101) C07C 41/09 (20130101) C07C 45/59 (20130101) C07C 45/60 (20130101) C07C 51/377 (20130101) Original (OR) Class Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/52 (20130101) C10G 2300/1014 (20130101) C10G 2300/1018 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 30/20 (20151101)
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09382294 — Broad spectrum antibiotic compounds and use thereof

US 09382294	Koglin et al.
FUNDED BY	Department of Energy (DOE) Los Alamos National Security, LLC (LANS) National Nuclear Security Administration (NNSA) Los Alamos National Laboratory (LANL) Federally Funded Research and Development Center (FFRDC) Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S)	Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S)	Alexander Koglin (Los Alamos, New Mexico); Matthias Strieker (Los Alamos, New Mexico)
ABSTRACT	The discovery of a non-ribosomal peptide synthetase (NRPS) gene cluster in the genome of Clostridium thermocellum that produces a secondary metabolite that is assembled outside of the host membrane is described. Also described is the identification of homologous NRPS gene clusters from several additional microorganisms. The secondary metabolites produced by the NRPS gene clusters exhibit broad spectrum antibiotic activity. Thus, antibiotic compounds produced by the NRPS gene clusters, and analogs thereof, their use for inhibiting bacterial growth, and methods of making the antibiotic compounds are described.
FILED	Friday, February 28, 2014
APPL NO	14/771710
ART UNIT	1673 — Organic Chemistry
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/00 (20130101) C07H 19/02 (20130101) Peptides C07K 9/006 (20130101) Original (OR) Class
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09382387 — Rapid self-assembly of block copolymers to photonic crystals

US 09382387	Xia et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	California Institute of Technology (Pasadena, California); The University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Yan Xia (Quincy, Massachusetts); Benjamin R Sveinbjornsson (Pasadena, California); Robert H Grubbs (South Pasadena, California); Raymond Weitekamp (Glendale, California); Garret M Miyake (Pasadena, California); Harry A Atwater (South Pasadena, California); Victoria Piunova (Altadena, California); Christopher Scot Daeffler (Pasadena, California); Sung Woo Hong (Seoul, South Korea); Weiyin Gu (Amherst, Massachusetts); Thomas P. Russell (Amherst, Massachusetts)
ABSTRACT	The invention provides a class of copolymers having useful properties, including brush block copolymers, wedge-type block copolymers and hybrid wedge and polymer block copolymers. In an embodiment, for example, block copolymers of the invention incorporate chemically different blocks comprising polymer size chain groups and/or wedge groups that significantly inhibit chain entanglement, thereby enhancing molecular self-assembly processes for generating a range of supramolecular structures, such as periodic nanostructures and microstructures. The present invention also provides useful methods of making and using copolymers, including block copolymers.
FILED	Wednesday, March 13, 2013
APPL NO	13/800646
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/027 (20130101) Original (OR) Class C08G 83/008 (20130101)
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09382449 — Optical enhancing durable anti-reflective coating

US 09382449	Maghsoodi et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	Enki Technology, Inc. (San Jose, California)
ASSIGNEE(S)	Enki Technology, Inc. (San Jose, California)
INVENTOR(S)	Sina Maghsoodi (San Jose, California); Aravamuthan Varadarajan (Fremont, California); Meisam Movassat (Atherton, California)
ABSTRACT	Disclosed herein are polysilsesquioxane based anti-reflective coating (ARC) compositions, methods of preparation, and methods of deposition on a substrate. In embodiments, the polysilsesquioxane of this disclosure is prepared in a two-step process of acid catalyzed hydrolysis of organoalkoxysilane followed by addition of tetralkoxysilane that generates silicone polymers with >40 mol % silanol based on Si-NMR. These high silanol siloxane polymers are stable and have a long shelf-life in the polar organic solvents at room temperature. Also disclosed are low refractive index ARC made from these compositions with and without additives such as porogens, templates, Si—OH condensation catalyst and/or nanofillers. Also disclosed are methods and apparatus for applying coatings to flat substrates including substrate pre-treatment processes, coating processes including flow coating and roll coating, and coating curing processes including skin-curing using hot-air knives. Also disclosed are coating compositions and formulations for highly tunable, durable, highly abrasion-resistant functionalized anti-reflective coatings.
FILED	Friday, September 19, 2014
APPL NO	14/491259
ART UNIT	1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/30 (20130101) C03C 2217/20 (20130101) C03C 2217/732 (20130101) C03C 2218/32 (20130101) C03C 2218/113 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0061 (20130101) C08J 9/142 (20130101) C08J 2383/04 (20130101) C08J 2471/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/36 (20130101) C08K 5/19 (20130101) C08K 7/26 (20130101) C08K 2003/045 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/04 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 1/14 (20150115) G02B 1/18 (20150115) G02B 1/111 (20130101)
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09382502 — Methods of refining and producing isomerized fatty acid esters and fatty acids from natural oil feedstocks

US 09382502	Snead et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	ELEVANCE RENEWABLE SCIENCES, INC. (Woodridge, Illinois)
ASSIGNEE(S)	Elevance Renewable Sciences, Inc. (Woodridge, Illinois)
INVENTOR(S)	Thomas E. Snead (Bolingbrook, Illinois); Steven A. Cohen (Naperville, Illinois); Demond L. Gildon (Romeoville, Illinois); Leslie V. Beltran (Aurora, Illinois); Linda A. Kunz (Naperville, Illinois); Tessa M. Pals (Chicago, Illinois); Jordan R. Quinn (Mundelein, Illinois); Raymond T. Behrends, Jr. (Lombard, Illinois); Randal J. Bernhardt (Antioch, Illinois)
ABSTRACT	Methods are provided for refining natural oil feedstocks and producing isomerized esters and acids. The methods comprise providing a C4-C18 unsaturated fatty ester or acid, and isomerizing the fatty acid ester or acid in the presence of heat or an isomerization catalyst to form an isomerized fatty ester or acid. In some embodiments, the methods comprise forming a dibasic ester or dibasic acid prior to the isomerizing step. In certain embodiments, the methods further comprise hydrolyzing the dibasic ester to form a dibasic acid. In certain embodiments, the olefin is formed by reacting the feedstock in the presence of a metathesis catalyst under conditions sufficient to form a metathesized product comprising olefins and esters, separating the olefins from the esters in the metathesized product, and transesterifying the esters in the presence of an alcohol to form a transesterified product having unsaturated esters.
FILED	Thursday, March 14, 2013
APPL NO	13/827798
ART UNIT	1672 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 3/42 (20130101) C10G 29/205 (20130101) C10G 45/00 (20130101) C10G 45/58 (20130101) C10G 50/00 (20130101) C10G 65/043 (20130101) C10G 69/123 (20130101) C10G 2300/30 (20130101) C10G 2300/1014 (20130101) C10G 2300/1018 (20130101) C10G 2300/1088 (20130101) C10G 2400/02 (20130101) C10G 2400/04 (20130101) C10G 2400/08 (20130101) C10G 2400/20 (20130101) C10G 2400/22 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/00 (20130101) C10L 1/02 (20130101) C10L 1/08 (20130101) C10L 1/026 (20130101) C10L 2200/0469 (20130101) C10L 2200/0476 (20130101) Producing, e.g by Pressing Raw Materials or by Extraction From Waste Materials, Refining or Preserving Fats, Fatty Substances, e.g Lanolin, Fatty Oils or Waxes; Essential Oils; Perfumes C11B 3/00 (20130101) Fatty Acids From Fats, Oils or Waxes; Candles; Fats, Oils or Fatty Acids by Chemical Modification of Fats, Oils, or Fatty Acids Obtained Therefrom C11C 3/003 (20130101) C11C 3/14 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/13 (20130101)
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09382553 — Host cells and methods for producing 1-deoxyxylulose 5-phosphate (DXP) and/or a DXP derived compound

US 09382553	Kirby et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	James Kirby (Berkeley, Arizona); Jeffrey L. Fortman (San Francisco, California); Minobu Nishimoto (El Cerrito, California); Jay D. Keasling (Berkeley, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	James Kirby (Berkeley, Arizona); Jeffrey L. Fortman (San Francisco, California); Minobu Nishimoto (El Cerrito, California); Jay D. Keasling (Berkeley, California)
ABSTRACT	The present invention provides for a genetically modified host cell capable of producing 1-deoxyxylulose 5-phosphate or 1-deoxy-D-xylulose 5-phosphate (DXP) (12), and optionally one or more DXP derived compounds, comprising: (a) a mutant RibB, or functional variant thereof, capable of catalyzing xylulose 5-phosphate and/or ribulose 5-phosphate to DXP, or (b) a YajO, or functional variant thereof, and a XylB, or functional variant thereof.
FILED	Thursday, August 16, 2012
APPL NO	13/587826
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) Original (OR) Class C12P 19/02 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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09382618 — Oxygen-free atomic layer deposition of indium sulfide

US 09382618	Martinson et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Argonne National Laboratory (ANL) Federally Funded Research and Development Center (FFRDC) Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S)	UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)	UChicago Argnonne, LLC (Chicago, Illinois)
INVENTOR(S)	Alex B. Martinson (Naperville, Illinois); Adam S. Hock (Chicago, Illinois); Robert McCarthy (Chicago, Illinois); Matthew S. Weimer (Chicago, Illinois)
ABSTRACT	A method for synthesizing an In(III) N,N′-diisopropylacetamidinate precursor including cooling a mixture comprised of diisopropylcarbodiimide and diethyl ether to approximately −30° C., adding methyllithium drop-wise into the mixture, allowing the mixture to warm to room temperature, adding indium(III) chloride as a solid to the mixture to produce a white solid, dissolving the white solid in pentane to form a clear and colorless solution, filtering the mixture over a celite plug, and evaporating the solution under reduced pressure to obtain a solid In(III) N,N′-diisopropylacetamidinate precursor. This precursor has been further used to develop a novel atomic layer deposition technique for indium sulfide by dosing a reactor with the precursor, purging with nitrogen, dosing with dilute hydrogen sulfide, purging again with nitrogen, and repeating these steps to increase growth.
FILED	Friday, July 18, 2014
APPL NO	14/335745
ART UNIT	1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/305 (20130101) Original (OR) Class C23C 16/45553 (20130101)
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09382632 — Electrochemical fluorination for processing of used nuclear fuel

US 09382632	Garcia-Diaz et al.
FUNDED BY	Department of Energy (DOE) Office of Environmental Management (DOE-EM) Savannah River National Laboratory (SRNL) Federally Funded Research and Development Center (FFRDC) Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S)	Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
ASSIGNEE(S)	Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S)	Brenda L. Garcia-Diaz (Aiken, South Carolina); Michael J. Martinez-Rodriguez (Aiken, South Carolina); Joshua R. Gray (Aiken, South Carolina); Luke C. Olson (North Augusta, South Carolina)
ABSTRACT	A galvanic cell and methods of using the galvanic cell is described for the recovery of uranium from used nuclear fuel according to an electrofluorination process. The galvanic cell requires no input energy and can utilize relatively benign gaseous fluorinating agents. Uranium can be recovered from used nuclear fuel in the form of gaseous uranium compound such as uranium hexafluoride, which can then be converted to metallic uranium or UO₂and processed according to known methodology to form a useful product, e.g., fuel pellets for use in a commercial energy production system.
FILED	Monday, June 23, 2014
APPL NO	14/312098
ART UNIT	1754 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC	Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/245 (20130101) Original (OR) Class C25B 15/02 (20130101) C25B 15/08 (20130101)
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09383098 — Radial flow fuel nozzle for a combustor of a gas turbine

US 09383098	Means et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	General Electric Company (Schenectady, New York)
ASSIGNEE(S)	GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S)	Gregory Scott Means (Simpsonville, South Carolina); Gregory Allen Boardman (Greer, South Carolina); Jonathan Dwight Berry (Simpsonville, South Carolina)
ABSTRACT	A combustor for a gas turbine generally includes a radial flow fuel nozzle having a fuel distribution manifold, and a fuel injection manifold axially separated from the fuel distribution manifold. The fuel injection manifold generally includes an inner side portion, an outer side portion, and a plurality of circumferentially spaced fuel ports that extend through the outer side portion. A plurality of tubes provides axial separation between the fuel distribution manifold and the fuel injection manifold. Each tube defines a fluid communication path between the fuel distribution manifold and the fuel injection manifold.
FILED	Wednesday, October 31, 2012
APPL NO	13/664705
ART UNIT	3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC	Burners F23D 11/24 (20130101) Original (OR) Class F23D 11/38 (20130101) F23D 14/00 (20130101) F23D 2900/00015 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/46 (20130101) F23R 3/283 (20130101) F23R 3/286 (20130101) F23R 3/343 (20130101) F23R 2900/00012 (20130101) F23R 2900/03044 (20130101)
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09383126 — Refrigerant charge management in a heat pump water heater

US 09383126	Chen et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	NORTEK GLOBAL HVAC LLC (O'Fallon, Missouri)
ASSIGNEE(S)	Nortek Global HVAC, LLC (O'Fallon, Missouri)
INVENTOR(S)	Jie Chen (St. Charles, Missouri); Justin W. Hampton (Bonne Terre, Missouri)
ABSTRACT	Heat pumps that heat or cool a space and that also heat water, refrigerant management systems for such heat pumps, and methods of managing refrigerant charge. Various embodiments remove idle refrigerant from a heat exchanger that is not needed for transferring heat by opening a refrigerant recovery valve and delivering the idle refrigerant from the heat exchanger to an inlet port on the compressor. The heat exchanger can be isolated by closing an electronic expansion valve, actuating a refrigerant management valve, or both. Refrigerant charge can be controlled by controlling how much refrigerant is drawn from the heat exchanger, by letting some refrigerant back into the heat exchanger, or both. Heat pumps can be operated in different modes of operation, and various components can be interconnected with refrigerant conduit. Some embodiments deliver refrigerant gas to the heat exchanger and drive liquid refrigerant out prior to isolating the heat exchanger.
FILED	Thursday, May 15, 2014
APPL NO	14/278982
ART UNIT	3744 — Static Structures, Supports and Furniture
CURRENT CPC	Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor F24D 19/1072 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 13/00 (20130101) F25B 29/003 (20130101) Original (OR) Class F25B 2313/005 (20130101) F25B 2313/0292 (20130101) F25B 2313/02731 (20130101) F25B 2313/02741 (20130101) F25B 2339/047 (20130101)
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09383270 — Silicon force sensor

US 09383270	Galambos et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Sandia National Laboratories (SNL) Federally Funded Research and Development Center (FFRDC) Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S)	Sandia Corporation (Albuquerque, New Mexico)
ASSIGNEE(S)	Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S)	Paul C. Galambos (Albuquerque, New Mexico); Thomas B. Crenshaw (Albuquerque, New Mexico); Erik E. Nishida (Albuquerque, New Mexico); Damon J. Burnett (Sandia Park, New Mexico); Jeffrey W. Lantz (Albuquerque, New Mexico)
ABSTRACT	The various technologies presented herein relate to a sensor for measurement of high forces and/or high load shock rate(s), whereby the sensor utilizes silicon as the sensing element. A plate of Si can have a thinned region formed therein on which can be formed a number of traces operating as a Wheatstone bridge. The brittle Si can be incorporated into a layered structure comprising ductile and/or compliant materials. The sensor can have a washer-like configuration which can be incorporated into a nut and bolt configuration, whereby tightening of the nut and bolt can facilitate application of a compressive preload upon the sensor. Upon application of an impact load on the bolt, the compressive load on the sensor can be reduced (e.g., moves towards zero-load), however the magnitude of the preload can be such that the load on the sensor does not translate to tensile stress being applied to the sensor.
FILED	Monday, October 28, 2013
APPL NO	14/064573
ART UNIT	2855 — Printing/Measuring and Testing
CURRENT CPC	Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Original (OR) Class G01L 5/0028 (20130101)
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09383452 — Spiral biasing adaptor for use in Si drift detectors and Si drift detector arrays

US 09383452	Li et al.
FUNDED BY	Department of Energy (DOE) Brookhaven Science Associates, LLC (BSA) Office of Science (DOE-SC) Brookhaven National Laboratory (BNL) Federally Funded Research and Development Center (FFRDC) Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)	BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York)
ASSIGNEE(S)	Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S)	Zheng Li (South Setauket, New York); Wei Chen (East Setauket, New York)
ABSTRACT	A drift detector array, preferably a silicon drift detector (SDD) array, that uses a low current biasing adaptor is disclosed. The biasing adaptor is customizable for any desired geometry of the drift detector single cell with minimum drift time of carriers. The biasing adaptor has spiral shaped ion-implants that generate the desired voltage profile. The biasing adaptor can be processed on the same wafer as the drift detector array and only one biasing adaptor chip/side is needed for one drift detector array to generate the voltage profiles on the front side and back side of the detector array.
FILED	Wednesday, October 24, 2012
APPL NO	14/352538
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Nuclear or X-radiation G01T 1/02 (20130101) Original (OR) Class G01T 1/2928 (20130101)
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09383460 — Beam imaging sensor

US 09383460	McAninch et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Babcock and Wilcox Nuclear Operations Group, Inc. (Lynchburg, Virginia)
ASSIGNEE(S)	BWXT Nuclear Operations Group, Inc. (Lynchburg, Virginia)
INVENTOR(S)	Michael D. McAninch (Goode, Virginia); Jeffrey J. Root (Columbus, Ohio)
ABSTRACT	The present invention relates generally to the field of sensors for beam imaging and, in particular, to a new and useful beam imaging sensor for use in determining, for example, the power density distribution of a beam including, but not limited to, an electron beam or an ion beam. In one embodiment, the beam imaging sensor of the present invention comprises, among other items, a circumferential slit that is either circular, elliptical or polygonal in nature.
FILED	Thursday, March 14, 2013
APPL NO	13/826907
ART UNIT	2881 — Optics
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 15/0026 (20130101) Measurement of Nuclear or X-radiation G01T 1/2921 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/244 (20130101) H01J 2237/3104 (20130101) H01J 2237/24405 (20130101) H01J 2237/24507 (20130101)
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09383968 — Math processing by detection of elementary valued operands

US 09383968	Finchelstein et al.
FUNDED BY	Department of Defense (DOD) Defense Advanced Research Projects Agency (DARPA) Department of Energy (DOE)
APPLICANT(S)	NVIDIA CORPORATION (Santa Clara, California)
ASSIGNEE(S)	NVIDIA Corporation (Santa Clara, California)
INVENTOR(S)	Daniel Finchelstein (Redwood City, California); David Conrad Tannenbaum (Austin, Texas); Srinivasan (Vasu) Iyer (Austin, Texas)
ABSTRACT	One embodiment of the present invention includes a method for simplifying arithmetic operations by detecting operands with elementary values such as zero or 1.0. Computer and graphics processing systems perform a great number of multiply-add operations. In a significant portion of these operations, the values of one or more of the operands are zero or 1.0. By detecting the occurrence of these elementary values, math operations can be greatly simplified, for example by eliminating multiply operations when one multiplicand is zero or 1.0 or eliminating add operations when one addend is zero. The simplified math operations resulting from detecting elementary valued operands provide significant savings in overhead power, dynamic processing power, and cycle time.
FILED	Friday, September 27, 2013
APPL NO	14/040370
ART UNIT	2183 — Computer Architecture and I/O
CURRENT CPC	Electric Digital Data Processing G06F 7/50 (20130101) Original (OR) Class G06F 7/5443 (20130101) G06F 2207/3884 (20130101)
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09384397 — Model for mapping settlements

US 09384397	Vatsavai et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Oak Ridge National Laboratory (ORNL) Federally Funded Research and Development Center (FFRDC) Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)	UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S)	Ranga Raju Vatsavai (Oak Ridge, Tennessee); Jordan B. Graesser (Oak Ridge, Tennessee); Budhendra L. Bhaduri (Oak Ridge, Tennessee)
ABSTRACT	A programmable media includes a graphical processing unit in communication with a memory element. The graphical processing unit is configured to detect one or more settlement regions from a high resolution remote sensed image based on the execution of programming code. The graphical processing unit identifies one or more settlements through the execution of the programming code that executes a multi-instance learning algorithm that models portions of the high resolution remote sensed image. The identification is based on spectral bands transmitted by a satellite and on selected designations of the image patches.
FILED	Thursday, August 22, 2013
APPL NO	13/973573
ART UNIT	2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00637 (20130101) Original (OR) Class G06K 9/4642 (20130101) G06K 9/4676 (20130101) G06K 9/6259 (20130101)
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09384870 — Mechanically robust, electrically conductive ultralow-density carbon nanotube-based aerogels

US 09384870	Worsley et al.
FUNDED BY	Department of Energy (DOE) National Nuclear Security Administration (NNSA) Lawrence Livermore National Laboratory (LLNL) Federally Funded Research and Development Center (FFRDC) Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)	LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S)	Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S)	Marcus A. Worsley (Hayward, California); Theodore F. Baumann (Discovery Bay, California); Joe H. Satcher, Jr. (Patterson, California)
ABSTRACT	A method of making a mechanically robust, electrically conductive ultralow-density carbon nanotube-based aerogel, including the steps of dispersing nanotubes in an aqueous media or other media to form a suspension, adding reactants and catalyst to the suspension to create a reaction mixture, curing the reaction mixture to form a wet gel, drying the wet gel to produce a dry gel, and pyrolyzing the dry gel to produce the mechanically robust, electrically conductive ultralow-density carbon nanotube-based aerogel. The aerogel is mechanically robust, electrically conductive, and ultralow-density, and is made of a porous carbon material having 5 to 95% by weight carbon nanotubes and 5 to 95% carbon binder.
FILED	Wednesday, February 12, 2014
APPL NO	14/179271
ART UNIT	1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/00 (20130101) C01B 31/0253 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/24 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/752 (20130101)
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09384879 — Magnetic multilayer structure

US 09384879	Herget et al.
FUNDED BY	Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S)	International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S)	INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S)	Philipp Herget (San Jose, California); Eugene J. O'Sullivan (Nyack, New York); Lubomyr T. Romankiw (Briarcliff Manor, New York); Naigang Wang (Ossining, New York); Bucknell C. Webb (Yorktown Heights, New York)
ABSTRACT	A mechanism is provided for an integrated laminated magnetic device. A substrate and a multilayer stack structure form the device. The multilayer stack structure includes alternating magnetic layers and diode structures formed on the substrate. Each magnetic layer in the multilayer stack structure is separated from another magnetic layer in the multilayer stack structure by a diode structure.
FILED	Wednesday, January 15, 2014
APPL NO	14/155552
ART UNIT	2897 — Semiconductors/Memory
CURRENT CPC	Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/021 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/0641 (20130101) H01L 28/10 (20130101)
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09385065 — Solid state thermal rectifier

US 09385065	Chang et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) Lawrence Berkeley National Laboratory (LBNL) Federally Funded Research and Development Center (FFRDC) Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S)	Chih-Wei Chang (Berkeley, California); Arunava Majumdar (Orinda, California); Alexander K. Zettl (Kensington, California)
ASSIGNEE(S)	The Regents of the University of California (Oakland, California)
INVENTOR(S)	Chih-Wei Chang (Berkeley, California); Arunava Majumdar (Orinda, California); Alexander K. Zettl (Kensington, California)
ABSTRACT	Thermal rectifiers using linear nanostructures as core thermal conductors have been fabricated. A high mass density material is added preferentially to one end of the nanostructures to produce an axially non-uniform mass distribution. The resulting nanoscale system conducts heat asymmetrically with greatest heat flow in the direction of decreasing mass density. Thermal rectification has been demonstrated for linear nanostructures that are electrical insulators, such as boron nitride nanotubes, and for nanostructures that are conductive, such as carbon nanotubes.
FILED	Tuesday, October 02, 2007
APPL NO	12/444149
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/0293 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/00 (20130101) F28F 21/02 (20130101) F28F 2013/008 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/373 (20130101) Original (OR) Class H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/30 (20150115) Y10T 428/24091 (20150115)
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09385285 — LED module with high index lens

US 09385285	Bierhuizen et al.
FUNDED BY	Department of Energy (DOE)
APPLICANT(S)	Serge J. Bierhuizen (Santa Rosa, California); Nanze Patrick Wang (San Jose, California); Gregory W. Eng (Fremont, California); Decai Sun (Los Altos, California); Yajun Wei (Sunnyvale, California)
ASSIGNEE(S)	KONINKLIJKE PHILIPS N.V. (Eindhoven, Netherlands); LUMILEDS LLC (San Jose, California)
INVENTOR(S)	Serge J. Bierhuizen (Santa Rosa, California); Nanze Patrick Wang (San Jose, California); Gregory W. Eng (Fremont, California); Decai Sun (Los Altos, California); Yajun Wei (Sunnyvale, California)
ABSTRACT	An array of housings with housing bodies and lenses is molded, or an array of housing bodies is molded and bonded with lenses to form an array of housings with housing bodies and lenses. Light-emitting diodes (LEDs) are attached to the housings in the array. An array of metal pads may be bonded to the back of the array or insert molded with the housing array to form bond pads on the back of the housings. The array is singulated to form individual LED modules.
FILED	Thursday, September 17, 2009
APPL NO	12/561617
ART UNIT	2815 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/58 (20130101) Original (OR) Class H01L 33/486 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101)
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09385348 — Organic electronic devices with multiple solution-processed layers

US 09385348	Forrest et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of Energy (DOE) Office of Science (DOE-SC)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	Stephen R. Forrest (Ann Arbor, Michigan); Brian E. Lassiter (San Francisco, California); Jeramy D. Zimmerman (Golden, Colorado)
ABSTRACT	A method for fabricating an organic light emitting device stack involves depositing a first conductive electrode layer over a substrate; depositing a first set of one or more organic layers, wherein at least one of the first set of organic layers is a first emissive layer and one of the first set of organic layers is deposited by a solution-based process that utilizes a first solvent; depositing a first conductive interlayer by a dry deposition process; and depositing a second set of one or more organic layers, wherein at least one of the second set of organic layers is a second emissive layer and one of the second set of organic layers is deposited by a solution-based process that utilizes a second solvent, wherein all layers that precede the layer deposited using the second solvent are insoluble in the second solvent.
FILED	Tuesday, August 04, 2015
APPL NO	14/817979
ART UNIT	2829 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/302 (20130101) H01L 51/001 (20130101) H01L 51/0003 (20130101) H01L 51/0007 (20130101) H01L 51/0021 (20130101) H01L 51/0026 (20130101) H01L 51/0028 (20130101) H01L 51/0047 (20130101) H01L 51/56 (20130101) Original (OR) Class H01L 51/424 (20130101) H01L 51/504 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5088 (20130101) H01L 51/5092 (20130101) H01L 51/5096 (20130101) H01L 51/5206 (20130101) H01L 51/5221 (20130101) H01L 51/5278 (20130101)
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09385392 — Semi-solid electrodes having high rate capability

US 09385392	Chiang et al.
FUNDED BY	Department of Energy (DOE) Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S)	24M Technologies, Inc. (Cambridge, Massachusetts)
ASSIGNEE(S)	24M Technologies, Inc. (Cambridge, Massachusetts)
INVENTOR(S)	Yet-Ming Chiang (Weston, Massachusetts); Mihai Duduta (Somerville, Massachusetts); Richard Holman (Wellesley, Massachusetts); Pimpa Limthongkul (Boston, Massachusetts); Taison Tan (Cambridge, Massachusetts)
ABSTRACT	Embodiments described herein relate generally to electrochemical cells having high rate capability, and more particularly to devices, systems and methods of producing high capacity and high rate capability batteries having relatively thick semi-solid electrodes. In some embodiments, an electrochemical cell includes an anode, a semi-solid cathode that includes a suspension of an active material and a conductive material in a liquid electrolyte, and an ion permeable membrane disposed between the anode and the cathode. The semi-solid cathode has a thickness in the range of about 250 μm-2,500 μm, and the electrochemical cell has an area specific capacity of at least 5 mAh/cm²at a C-rate of C/2.
FILED	Monday, October 05, 2015
APPL NO	14/875076
ART UNIT	1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC	Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) H01M 8/18 (20130101) H01M 8/20 (20130101) H01M 8/188 (20130101) H01M 8/225 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/528 (20130101)
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09386676 — Apparatus for magnetic and electrostatic confinement of plasma

US 09386676	Rostoker et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) Department of Energy (DOE)
APPLICANT(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S)	Norman Rostoker (Irvine, California); Michl Binderbauer (Irvine, California)
ABSTRACT	An apparatus and method for containing plasma and forming a Field Reversed Configuration (FRC) magnetic topology are described in which plasma ions are contained magnetically in stable, non-adiabatic orbits in the FRC. Further, the electrons are contained electrostatically in a deep energy well, created by tuning an externally applied magnetic field. The simultaneous electrostatic confinement of electrons and magnetic confinement of ions avoids anomalous transport and facilitates classical containment of both electrons and ions. In this configuration, ions and electrons may have adequate density and temperature so that upon collisions ions are fused together by nuclear force, thus releasing fusion energy. Moreover, the fusion fuel plasmas that can be used with the present confinement system and method are not limited to neutronic fuels only, but also advantageously include advanced fuels.
FILED	Tuesday, June 11, 2013
APPL NO	13/915521
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Fusion Reactors G21B 1/052 (20130101) Nuclear Power Plant G21D 7/00 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/03 (20130101) H05H 1/14 (20130101) H05H 1/16 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/122 (20130101)
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09386682 — Distributed coupling and multi-frequency microwave accelerators

US 09386682	Tantawi et al.
FUNDED BY	Department of Energy (DOE) Office of Science (DOE-SC) SLAC National Accelerator Laboratory (SLAC) Federally Funded Research and Development Center (FFRDC) Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S)	The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S)	Sami G. Tantawi (Stanford, California); Zenghai Li (Sunnyvale, California); Philipp Borchard (San Francisco, California)
ABSTRACT	A microwave circuit for a linear accelerator has multiple metallic cell sections, a pair of distribution waveguide manifolds, and a sequence of feed arms connecting the manifolds to the cell sections. The distribution waveguide manifolds are connected to the cell sections so that alternating pairs of cell sections are connected to opposite distribution waveguide manifolds. The distribution waveguide manifolds have concave modifications of their walls opposite the feed arms, and the feed arms have portions of two distinct widths. In some embodiments, the distribution waveguide manifolds are connected to the cell sections by two different types of junctions adapted to allow two frequency operation. The microwave circuit may be manufactured by making two quasi-identical parts, and joining the two parts to form the microwave circuit, thereby allowing for many manufacturing techniques including electron beam welding, and thereby allowing the use of un-annealled copper alloys, and hence greater tolerance to high gradient operation.
FILED	Thursday, July 09, 2015
APPL NO	14/795490
ART UNIT	2844 — Electrical Circuits and Systems
CURRENT CPC	Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/207 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/02 (20130101) Original (OR) Class H05H 9/00 (20130101) H05H 2007/027 (20130101)
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National Science Foundation (NSF)

09380784 — Antimicrobial compositions and methods of use

US 09380784	Derby et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Science Foundation (NSF) Directorate for Biological Sciences (BIO) Division of Integrative Biology and Neuroscience (IBN)
APPLICANT(S)	Charles Derby (Decatur, Georgia); Binghe Wang (Marietta, Georgia); Phang C. Tai (Atlanta, Georgia); Ko-Chun Ko (Atlanta, Georgia); Michiya Kamio (Tokyo, Japan)
ASSIGNEE(S)
INVENTOR(S)	Charles Derby (Decatur, Georgia); Binghe Wang (Marietta, Georgia); Phang C. Tai (Atlanta, Georgia); Ko-Chun Ko (Atlanta, Georgia); Michiya Kamio (Tokyo, Japan)
ABSTRACT	Disclosed herein are antimicrobial compositions, kits, and articles of manufacture. Further disclosed herein are methods for treating surfaces, including tissue, inter alia, wounds, with the disclosed compositions.
FILED	Monday, July 27, 2009
APPL NO	13/055221
ART UNIT	1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/22 (20130101) A01N 31/02 (20130101) A01N 37/42 (20130101) A01N 37/44 (20130101) A01N 37/50 (20130101) A01N 59/00 (20130101) Original (OR) Class A01N 59/00 (20130101) A01N 59/00 (20130101) A01N 2300/00 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

09380950 — Methods for detecting biological rhythm disorders

US 09380950	Narayan et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) National Science Foundation (NSF) Office of The Director (OD) Office of General Counsel(OGC)
APPLICANT(S)	The Regents of the University of California (Oakland, California)
ASSIGNEE(S)	THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFARIS, OFFICE OF GENERAL COUNSEL (Washington, District of Columbia)
INVENTOR(S)	Sanjiv Narayan (La Jolla, California); Wouter-Jan Rappel (San Diego, California)
ABSTRACT	A method of detecting a cause of a heart rhythm disorder includes collecting data corresponding to activation onset time of each heart activation at multiple locations of the heart and generating an activation trail based on the sequential order of activation onset times. The activation trail is indicative of the cause of the heart rhythm disorder.
FILED	Monday, August 12, 2013
APPL NO	13/964604
ART UNIT	3766 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/04 (20130101) A61B 5/044 (20130101) A61B 5/046 (20130101) A61B 5/0245 (20130101) A61B 5/0402 (20130101) A61B 5/0452 (20130101) A61B 5/0464 (20130101) A61B 5/726 (20130101) A61B 5/02405 (20130101) Original (OR) Class A61B 5/04011 (20130101) A61B 5/04012 (20130101) A61B 5/4836 (20130101) A61B 5/7203 (20130101) A61B 18/1206 (20130101) A61B 18/1492 (20130101) A61B 2018/00214 (20130101) A61B 2018/00357 (20130101) A61B 2018/00375 (20130101) A61B 2018/00839 (20130101) A61B 2018/1435 (20130101)
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09381158 — Nanoparticle fabrication methods, systems, and materials for fabricating artificial red blood cells

US 09381158	DeSimone et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S)	The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S)	Joseph M. DeSimone (Chapel Hill, North Carolina); Edward T. Samulski (Chapel Hill, North Carolina)
ABSTRACT	A plurality of artificial red blood cell particles includes each particle of the plurality being substantially monodisperse and each particle having a largest common linear dimension of about 5 μm to about 10 μm. The particles can also have a modulus configured such that a particle of the plurality of particles can pass through a tube having an inner diameter of less than about 3 μm.
FILED	Wednesday, May 29, 2013
APPL NO	13/904517
ART UNIT	1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0026 (20130101) A61K 9/1641 (20130101) Original (OR) Class A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 35/18 (20130101) A61K 38/42 (20130101) A61K 47/34 (20130101) A61K 51/1244 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 2400/12 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 71/02 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/832 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115)
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09381528 — Articles for manipulating impinging liquids and methods of manufacturing same

US 09381528	Dhiman et al.
FUNDED BY	Department of Defense (DOD) Department of the Navy (DON) Space and Naval Warfare Systems Center (SPAWAR) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Rajeev Dhiman (Glastonbury, Connecticut); James C. Bird (Cambridge, Massachusetts); Hyukmin Kwon (Cambridge, Massachusetts); Kripa K. Varanasi (Lexington, Massachusetts)
ABSTRACT	This invention relates generally to an article that includes a non-wetting surface having a dynamic contact angle of at least about 90°. The surface is patterned with macro-scale features configured to induce controlled asymmetry in a liquid film produced by impingement of a droplet onto the surface, thereby reducing time of contact between the droplet and the surface.
FILED	Wednesday, June 11, 2014
APPL NO	14/302112
ART UNIT	1783 — Miscellaneous Articles, Stock Material
CURRENT CPC	Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/26 (20130101) Original (OR) Class Processes for Applying Fluent Materials to Surfaces, in General B05D 1/185 (20130101) B05D 5/02 (20130101) B05D 5/083 (20130101) Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24355 (20150115)
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09381568 — System and method for making structured magnetic material from insulated particles

US 09381568	Hosek et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts)
ASSIGNEE(S)	Persimmon Technologies Corporation (Wakefield, Massachusetts)
INVENTOR(S)	Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts)
ABSTRACT	A system for making a material having domains with insulated boundaries is provided. The system includes a combustion chamber, a gas inlet configured to inject a gas into the combustion chamber, a fuel inlet configured to inject a fuel into the combustion chamber, an igniter subsystem configured to ignite a mixture of the gas and the fuel to create a predetermined temperature and pressure in the combustion chamber, a metal powder inlet configured to inject a metal powder comprised of particles coated with an electrically insulating material into the combustion, wherein the predetermined temperature creates conditioned droplets comprised of the metal powder in the chamber, and an outlet configured to eject and accelerate combustion gases and the conditioned droplets from the combustion chamber and towards a surface such that conditioned droplets adhere to the surface to form a material having domains with insulated boundaries thereon.
FILED	Friday, June 29, 2012
APPL NO	13/507451
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Original (OR) Class Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/115 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/18 (20130101) C23C 6/00 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/24 (20130101) H01F 3/08 (20130101) H01F 41/0246 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24413 (20150115)
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09382127 — Catalytic CO₂desorption on the interface between NaHCO₃ and multifunctional nanoporous TiO(OH)₂

US 09382127	Fan
FUNDED BY	National Science Foundation (NSF) Directorate for Education and Human Resources (EHR) Division of Graduate Education (DGE)
APPLICANT(S)	Maohong Fan (Kent, Iowa)
ASSIGNEE(S)
INVENTOR(S)	Maohong Fan (Kent, Iowa)
ABSTRACT	CO₂capture from flue gas is a costly procedure, usually due to the energy required for regeneration of the capture medium. One potential medium which could reduce such an energy consumption, however, is Na₂CO₃. It has been well studied as a sorbent, and it is understood that the theoretical energy penalty of use of Na₂CO₃for CO₂separation is low, due to the relatively low heat of reaction and low heat capacity of the material. While it offers some advantages over other methods, its primary downfall is the slow reaction with CO₂during adsorption and the slow Na₂CO₃regeneration process. An aspect of the invention relates to a catalyst to improve reaction kinetics, and more particularly to a catalyst to improve reaction kinetics for CO₂desorption and CO₂adsorption.
FILED	Friday, May 11, 2012
APPL NO	13/469895
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Separation B01D 53/62 (20130101) B01D 53/96 (20130101) B01D 2251/304 (20130101) B01D 2255/2065 (20130101) B01D 2255/2092 (20130101) B01D 2255/20707 (20130101) B01D 2255/20738 (20130101) B01D 2257/504 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/043 (20130101) B01J 20/3078 (20130101) B01J 20/3085 (20130101) B01J 20/3204 (20130101) B01J 20/3236 (20130101) B01J 20/28057 (20130101) B01J 20/28071 (20130101) B01J 20/28083 (20130101) B01J 21/063 (20130101) B01J 27/232 (20130101) B01J 2220/42 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 23/04 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 10/04 (20130101) Y02C 10/08 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/152 (20151101)
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09382291 — Gamma amino acid building blocks

US 09382291	Gellman et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Samuel Helmer Gellman (Madison, Wisconsin); Li Guo (Blue Bell, Pennsylvania); Michael Giuliano (Derby, Connecticut)
ABSTRACT	The invention provides compounds and methods, for example, to carry out organocatalytic Michael additions of aldehydes to cyclically constrained nitroethylene compounds catalyzed by a proline derivative to provide cyclically constrained α-substituted-γ-nitro-aldehydes. The reaction can be rendered enantioselective when a chiral pyrrolidine catalyst is used, allowing for Michael adducts in nearly optically pure form (e.g., 96 to >99% e.e.). The Michael adducts can bear a single substituent or dual substituents adjacent to the carbonyl. The Michael adducts can be efficiently converted to cyclically constrained protected γ-amino acid residues, which are essential for systematic conformational studies of γ-peptide foldamers. New methods are also provided to prepare other γ-amino acids and peptides. These new building blocks can be used to prepare foldamers, such as α/γ-peptide foldamers, that adopt specific helical conformations in solution and in the solid state.
FILED	Tuesday, January 28, 2014
APPL NO	14/166007
ART UNIT	1675 — Organic Chemistry
CURRENT CPC	Acyclic or Carbocyclic Compounds C07C 201/12 (20130101) C07C 205/44 (20130101) C07C 205/55 (20130101) C07C 233/48 (20130101) C07C 237/24 (20130101) C07C 269/00 (20130101) C07C 271/24 (20130101) C07C 271/66 (20130101) C07C 2101/08 (20130101) C07C 2101/14 (20130101) Heterocyclic Compounds C07D 211/56 (20130101) C07D 211/60 (20130101) Peptides C07K 5/0205 (20130101) C07K 5/1016 (20130101) C07K 5/06078 (20130101) C07K 7/06 (20130101) Original (OR) Class
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09382387 — Rapid self-assembly of block copolymers to photonic crystals

US 09382387	Xia et al.
FUNDED BY	Department of Energy (DOE) Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Chemistry (CHE)
APPLICANT(S)	California Institute of Technology (Pasadena, California); The University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)	CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S)	Yan Xia (Quincy, Massachusetts); Benjamin R Sveinbjornsson (Pasadena, California); Robert H Grubbs (South Pasadena, California); Raymond Weitekamp (Glendale, California); Garret M Miyake (Pasadena, California); Harry A Atwater (South Pasadena, California); Victoria Piunova (Altadena, California); Christopher Scot Daeffler (Pasadena, California); Sung Woo Hong (Seoul, South Korea); Weiyin Gu (Amherst, Massachusetts); Thomas P. Russell (Amherst, Massachusetts)
ABSTRACT	The invention provides a class of copolymers having useful properties, including brush block copolymers, wedge-type block copolymers and hybrid wedge and polymer block copolymers. In an embodiment, for example, block copolymers of the invention incorporate chemically different blocks comprising polymer size chain groups and/or wedge groups that significantly inhibit chain entanglement, thereby enhancing molecular self-assembly processes for generating a range of supramolecular structures, such as periodic nanostructures and microstructures. The present invention also provides useful methods of making and using copolymers, including block copolymers.
FILED	Wednesday, March 13, 2013
APPL NO	13/800646
ART UNIT	1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC	Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/027 (20130101) Original (OR) Class C08G 83/008 (20130101)
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09383292 — Flexible fiber-based micro and nanofluidics for probing liquids

US 09383292	Kornev et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI) Office of Emerging Frontiers in Research and Innovation (EFRI)
APPLICANT(S)	Konstantin G. Kornev (Clemson, South Carolina); Chen-Chih Tsai (New Taipei, Taiwan); David Lukas (Rochlice, Czech Republic); Petr Mikes (Liberce, Czech Republic)
ASSIGNEE(S)	CLEMSON UNIVERSITY (Clemson, South Carolina)
INVENTOR(S)	Konstantin G. Kornev (Clemson, South Carolina); Chen-Chih Tsai (New Taipei, Taiwan); David Lukas (Rochlice, Czech Republic); Petr Mikes (Liberce, Czech Republic)
ABSTRACT	A fluidic probe comprising a plurality of oriented fibers with individual fibers having nano-pores in the fiber bodies, the oriented fibers being twisted together, wherein the twisted oriented fibers form micro-pores between the individual fibers, is disclosed. The fluidic probe exhibits excellent flexibility, deployability and absorptive capacity. The enhanced absorptive capacity is due to the fluid absorption via capillary action of the nano-pores and fluid transport via the micro-pores. The probes can also be formed so as to be remotely controlled by electromagnetic fields and thus be used in a hands-free fashion. With these probes, the paradigm of a stationary microfluidic platform can be shifted to include flexible structures that can include multiple microfluidic sensors in a single fibrous probe.
FILED	Wednesday, September 12, 2012
APPL NO	13/611971
ART UNIT	1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC	Separation B01D 2239/025 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/32 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) Original (OR) Class
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09383387 — System for lightweight image processing

US 09383387	Jermyn et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S)	THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S)	Adam Sean Jermyn (Longmeadow, Massachusetts); Justin David Silverman (Pacific Palisades, California); Nina Markovic (Baltimore, Maryland)
ABSTRACT	An embodiment in accordance with the present invention provides a system and method for image analysis and processing. The present invention provides a software package for processing AFM data. More particularly it can be used for characterizing carbon nanotubes found within AFM images, though it does offer editing features that are general in nature. Its features are split amongst five menus, one button, and four data panels. The software package can be used to determine physical characteristics related to the imaged subject, such as, for instance length data for imaged carbon nanotubes.
FILED	Friday, June 26, 2015
APPL NO	14/751769
ART UNIT	2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC	Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 2202/34 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/04 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0014 (20130101) G06K 9/50 (20130101) Image Data Processing or Generation, in General G06T 5/20 (20130101) G06T 7/0083 (20130101) G06T 7/602 (20130101) G06T 2207/30108 (20130101)
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09383797 — Electronic computer providing power/performance management

US 09383797	Sen et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Rathijit Sen (Madison, Wisconsin); David A Wood (Madison, Wisconsin)
ABSTRACT	Computational resources of an electronic computer are monitored by predictors that establish predicted trade-offs between performance and power for a particular workload while the workload is being executed. A coordinator combines prediction values to identify a limited number of combinations of operating states of the computational resources, allowing operating states of the computational resources to be readily adapted during program execution based on a particular workload. The limited number of combinations of operating states are ideally Pareto optimal combinations.
FILED	Thursday, January 09, 2014
APPL NO	14/151073
ART UNIT	2118 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Electric Digital Data Processing G06F 1/329 (20130101) G06F 1/3203 (20130101) Original (OR) Class G06F 9/5094 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/144 (20130101)
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09384016 — Method of estimating program speed-up with highly parallel architectures

US 09384016	Sankaralingam et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Karthikeyan Sankaralingam (Madison, Wisconsin); Newsha Ardalani (Madison, Wisconsin); Xiaojin Zhu (Middleton, Wisconsin)
ABSTRACT	The amount of speed-up that can be obtained by moving a program to a parallel architecture is determined by a model associating speed-up to micro-architecture independent features of the program execution. The model may be generated, for example, by linear regression, by evaluating programs that have been ported to parallel architectures where the micro-architecture independent features are known.
FILED	Friday, March 14, 2014
APPL NO	14/212711
ART UNIT	2194 — Interprocess Communication and Software Development
CURRENT CPC	Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0294 (20130101) Electric Digital Data Processing G06F 8/443 (20130101) G06F 9/54 (20130101) G06F 9/44505 (20130101) Original (OR) Class
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09384858 — Computer system predicting memory failure

US 09384858	Yazdanbakhsh et al.
FUNDED BY	National Science Foundation (NSF)
APPLICANT(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S)	Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S)	Amir Yazdanbakhsh (Atlanta, Georgia); Raghuraman Balasubramanian (Bellevue, Washington); Anthony Nowatzki (Madison, Wisconsin); Karthikeyan Sankaralingam (Madison, Wisconsin)
ABSTRACT	The prediction of memory failure is obtained by reducing the voltage on a bank of memory cells to momentarily artificially age the memory cells and subjecting the memory cells to a test in which one or more predetermined vectors are written to and read from the memory cells to detect memory cell errors.
FILED	Friday, November 21, 2014
APPL NO	14/549979
ART UNIT	2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC	Static Stores G11C 11/419 (20130101) G11C 29/38 (20130101) Original (OR) Class G11C 29/42 (20130101) G11C 29/50004 (20130101)
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09384877 — Magneto dielectric polymer nanocomposites and method of making

US 09384877	Weller et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S)	Thomas Weller (Lutz, Florida); Jing Wang (Tampa, Florida); Hariharan Srikanth (Tampa, Florida); Cesar A. Morales-Silva (Greensboro, North Carolina); Kristen L. S. Repa (Tampa, Florida); Susmita Pal (Tampa, Florida)
ASSIGNEE(S)	University of South Florida (Tampa, Florida)
INVENTOR(S)	Thomas Weller (Lutz, Florida); Jing Wang (Tampa, Florida); Hariharan Srikanth (Tampa, Florida); Cesar A. Morales-Silva (Greensboro, North Carolina); Kristen L. S. Repa (Tampa, Florida); Susmita Pal (Tampa, Florida)
ABSTRACT	In accordance with the present invention, novel superparamagnetic magneto-dielectric polymer nanocomposites are synthesized using a novel process. The tunability of the dielectric/magnetic properties demonstrated by this novel highly-viscous solvent-free polymer nanocomposite that is amenable to building 3D electromagnetic structures/devices by using processes such as 3D printing, compression molding or injection molding, when an external DC magnetic field is applied, exceeds what has been previously reported for magneto-dielectric polymer nanocomposite materials.
FILED	Monday, April 13, 2015
APPL NO	14/685031
ART UNIT	1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 9/04 (20130101) C08K 2201/01 (20130101) C08K 2201/011 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/006 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/01 (20130101) H01F 1/0018 (20130101) Original (OR) Class H01F 41/005 (20130101)
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09385332 — Organic-inorganic hybrid multilayer gate dielectrics for thin film transistors

US 09385332	Marks et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Office of Scientific Research (AFOSR) Department of the Navy (DON) Office of Naval Research (ONR) National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences (MPS) Division of Materials Research (DMR)
APPLICANT(S)	Northwestern University (Evanston, Illinois)
ASSIGNEE(S)	Northwestern University (Evanston, Illinois)
INVENTOR(S)	Tobin J. Marks (Evanston, Illinois); Young-geun Ha (Evanston, Illinois); Antonio Facchetti (Chicago, Illinois)
ABSTRACT	Disclosed are organic-inorganic hybrid self-assembled multilayers that can be used as electrically insulating (or dielectric) materials. These multilayers generally include an inorganic primer layer and one or more bilayers deposited thereon. Each bilayer includes a chromophore or “π-polarizable” layer and an inorganic capping layer composed of zirconia. Because of the regularity of the bilayer structure and the aligned orientation of the chromophore resulting from the self-assembly process, the present multilayers have applications in electronic devices such as thin film transistors, as well as in nonlinear optics and nonvolatile memories.
FILED	Tuesday, September 08, 2015
APPL NO	14/848281
ART UNIT	2898 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/441 (20130101) H01L 29/24 (20130101) H01L 29/513 (20130101) H01L 29/517 (20130101) H01L 29/4908 (20130101) H01L 29/66969 (20130101) H01L 51/0529 (20130101) H01L 51/0533 (20130101) Original (OR) Class H01L 51/0537 (20130101) H01L 51/0545 (20130101) H01L 2251/301 (20130101)
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09385692 — Low power oscillator with charge subtraction scheme

US 09385692	Blaauw et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S)	The Regents Of The University Of Michigan (Ann Arbor, Michigan)
INVENTOR(S)	David T. Blaauw (Ann Arbor, Michigan); Dennis Sylvester (Ann Arbor, Michigan); Seok Hyeon Jeong (Ann Arbor, Michigan)
ABSTRACT	An ultra-low power oscillator is designed for wake-up timers that can be used in compact wireless sensors, for example. A constant charge subtraction scheme removes continuous comparator delay from the oscillation period, which is the source of temperature dependence in conventional RC relaxation oscillators. This relaxes comparator design constraints, enabling low power operation. In 0.18 μm CMOS, the oscillator consumes 5.8 nW at room temperature with temperature stability of 45 ppm/° C. (−10° C. to 90° C.) and 1%/V line sensitivity.
FILED	Wednesday, March 18, 2015
APPL NO	14/661279
ART UNIT	2842 — Electrical Circuits and Systems
CURRENT CPC	Pulse Technique H03K 3/011 (20130101) H03K 3/012 (20130101) H03K 3/0231 (20130101) Original (OR) Class H03K 4/502 (20130101)
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09386027 — Detection of pileup vulnerabilities in mobile operating systems

US 09386027	Xing et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of Neurological Disorders and Stroke (NINDS) National Science Foundation (NSF) Directorate for Computer and Information Science and Engineering (CISE) Division of Computer and Network Systems (CNS)
APPLICANT(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
ASSIGNEE(S)	Indiana University Research and Technology Corporation (Indianapolis, Indiana)
INVENTOR(S)	Luyi Xing (Bloomington, Indiana); XiaoFeng Wang (Bloomington, Indiana)
ABSTRACT	A system is provided for detecting pileup vulnerabilities corresponding to mobile operating system updates. The system includes: an exploit opportunity analyzer, configured to identify pileup exploit opportunities corresponding to a plurality of mobile operating system configurations based on mobile operating system upgrades for each of the plurality of mobile operating system configurations, wherein the identification of exploit opportunities is based on information relating to pileup flaws; a risk database, configured to store information regarding the identified pileup exploit opportunities for a plurality of versions of each of the plurality of mobile operating system configurations; and a scanner application, configured to be executed by a mobile device, configured to query identified exploit opportunities relating to a particular mobile operating system configuration and version, and to evaluate third-party applications installed at the mobile device based on the identified exploit opportunities.
FILED	Monday, August 11, 2014
APPL NO	14/456719
ART UNIT	2493 — Cryptography and Security
CURRENT CPC	Transmission of Digital Information, e.g Telegraphic Communication H04L 63/14 (20130101) Original (OR) Class
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National Aeronautics and Space Administration (NASA)

09381802 — Propulsion wheel motor for an electric vehicle

US 09381802	Figuered et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan); The United States of America As Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	GM Global Technology Operations LLC (Detroit, Michigan); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Joshua M. Figuered (Houston, Texas); Eduardo Herrera (Houston, Texas); Thomas M. Waligora (Houston, Texas); William J. Bluethmann (Houston, Texas); Logan Christopher Farrell (West Lafayette, Indiana); Chunhao J. Lee (Troy, Michigan); Robert L. Vitale (Macomb Township, Michigan); Ross Briant Winn (Houston, Texas); Raymond Edward Eggleston, IV (Canton, Georgia); Raymond Guo (Seabrook, Texas); Steven J. Weber (Mount Clemens, Michigan); Lucien Q. Junkin (Houston, Texas); James Jonathan Rogers (League City, Texas)
ABSTRACT	A wheel assembly for an electric vehicle includes a wheel rim that is concentrically disposed about a central axis. A propulsion-braking module is disposed within an interior region of the wheel rim. The propulsion-braking module rotatably supports the wheel rim for rotation about the central axis. The propulsion-braking module includes a liquid cooled electric motor having a rotor rotatable about the central axis, and a stator disposed radially inside the rotor relative to the central axis. A motor-wheel interface hub is fixedly attached to the wheel rim, and is directly attached to the rotor for rotation with the rotor. The motor-wheel interface hub directly transmits torque from the electric motor to the wheel rim at a 1:1 ratio. The propulsion-braking module includes a drum brake system having an electric motor that rotates a cam device, which actuates the brake shoes.
FILED	Wednesday, October 23, 2013
APPL NO	14/061073
ART UNIT	3618 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC	Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 27/0057 (20130101) B60B 27/0068 (20130101) B60B 2900/513 (20130101) Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 7/0007 (20130101) Original (OR) Class B60K 11/02 (20130101) B60K 17/356 (20130101) B60K 2001/006 (20130101) B60K 2007/0038 (20130101) B60K 2007/0092 (20130101)
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09382000 — Aircraft design

US 09382000	Bowers et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Albion H. Bowers (Lancaster, California); Edward Uden (Barnstedt, Germany)
ABSTRACT	The present invention is an aircraft wing design that creates a bell shaped span load, which results in a negative induced drag (induced thrust) on the outer portion of the wing; such a design obviates the need for rudder control of an aircraft.
FILED	Thursday, June 05, 2014
APPL NO	14/297186
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Aeroplanes; Helicopters B64C 3/14 (20130101) B64C 23/065 (20130101) Original (OR) Class
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09382020 — Deep space positioning system

US 09382020	Vaughan et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Andrew T. Vaughan (Superior, Colorado); Joseph E. Riedel (Littlerock, California)
ABSTRACT	A single, compact, lower power deep space positioning system (DPS) configured to determine a location of a spacecraft anywhere in the solar system, and provide state information relative to Earth, Sun, or any remote object. For example, the DPS includes a first camera and, possibly, a second camera configured to capture a plurality of navigation images to determine a state of a spacecraft in a solar system. The second camera is located behind, or adjacent to, a secondary reflector of a first camera in a body of a telescope.
FILED	Wednesday, August 27, 2014
APPL NO	14/470438
ART UNIT	3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC	Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/52 (20130101) B64G 1/66 (20130101) Original (OR) Class B64G 3/00 (20130101)
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09383143 — Metallic thin-film bonding and alloy generation

US 09383143	Fryer et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Johnson Space Center (JSC) NASA Shared Services Center (NSSC)
APPLICANT(S)	Micro Cooling Concepts, Inc. (Huntington Beach, California)
ASSIGNEE(S)	Micro Cooling Concepts, Inc. (Huntington Beach, California)
INVENTOR(S)	Jack Merrill Fryer (Huntington Beach, California); Geoff Campbell (Broomfield, Colorado); Brian S. Peotter (Costa Mesa, California); Lloyd Droppers (Sunnyvale, California)
ABSTRACT	Diffusion bonding a stack of aluminum thin films is particularly challenging due to a stable aluminum oxide coating that rapidly forms on the aluminum thin films when they are exposed to atmosphere and the relatively low meting temperature of aluminum. By plating the individual aluminum thin films with a metal that does not rapidly form a stable oxide coating, the individual aluminum thin films may be readily diffusion bonded together using heat and pressure. The resulting diffusion bonded structure can be an alloy of choice through the use of a carefully selected base and plating metals. The aluminum thin films may also be etched with distinct patterns that form a microfluidic fluid flow path through the stack of aluminum thin films when diffusion bonded together.
FILED	Thursday, September 25, 2014
APPL NO	14/497113
ART UNIT	1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/002 (20130101) B23K 20/02 (20130101) B23K 20/023 (20130101) B23K 20/24 (20130101) B23K 20/026 (20130101) B23K 2201/14 (20130101) B23K 2203/10 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0308 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/8593 (20150401)
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09383254 — Symmetric absorber-coupled far-infrared microwave kinetic inductance detector

US 09383254	U-yen et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	The United States of America as represented by the Administrator of the National Aeronotics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S)	Kongpop U-yen (Arlington, Virginia); Edward J. Wollack (Clarksville, Maryland); Ari D. Brown (Baltimore, Maryland); Thomas R. Stevenson (Rockville, Maryland); Amil A. Patel (Palo Alto, California)
ABSTRACT	The present invention relates to a symmetric absorber-coupled far-infrared microwave kinetic inductance detector including: a membrane having an absorber disposed thereon in a symmetric cross bar pattern; and a microstrip including a plurality of conductor microstrip lines disposed along all edges of the membrane, and separated from a ground plane by the membrane. The conducting microstrip lines are made from niobium, and the pattern is made from a superconducting material with a transition temperature below niobium, including one of aluminum, titanium nitride, or molybdenum nitride. The pattern is disposed on both a top and a bottom of the membrane, and creates a parallel-plate coupled transmission line on the membrane that acts as a half-wavelength resonator at readout frequencies. The parallel-plate coupled transmission line and the conductor microstrip lines form a stepped impedance resonator. The pattern provides identical power absorption for both horizontal and vertical polarization signals.
FILED	Thursday, September 25, 2014
APPL NO	14/497238
ART UNIT	2884 — Optics
CURRENT CPC	Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/10 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/082 (20130101)
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09383520 — Optical power transfer system for powering a remote mobility system for multiple missions

US 09383520	Stone et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	Piedra-Sombra Corporation, Inc. (Del Valle, Texas)
ASSIGNEE(S)	Piedra-Sombra Corporation, Inc. (Del Valle, Texas)
INVENTOR(S)	William C. Stone (Del Valle, Texas); Bartholomew P. Hogan (Rockville, Maryland)
ABSTRACT	An optical power transfer system for powering a remote mobility system for multiple missions comprising a high power source and a chilling station connected to a laser source. The laser source transmits a high optical energy to a beam switch assembly via an optical fiber. The beam switch assembly is optically connected to actively cooled fiber spoolers. Docking stations are adapted for securing the fiber spoolers until alternatively ready for use by a remote mobility system. The remote mobility system is optically connected to the fiber spoolers and has a receiving port adapted for securing the fiber spoolers thereon. The fiber spooler transmits the optical energy to a power conversion system which converts the optical energy received to another usable form of energy. More than one power source may be used where the remote mobility system transfers from one source to another while maintaining an operational radius to each source.
FILED	Wednesday, May 27, 2015
APPL NO	14/723206
ART UNIT	2883 — Optics
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/12 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/00 (20130101) Street Cleaning; Cleaning of Permanent Ways; Cleaning Beaches; Dispersing Fog in General E01H 5/10 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 41/0085 (20130101) E21B 47/123 (20130101) Producing, Working or Handling Ice F25C 5/08 (20130101) Optical Elements, Systems, or Apparatus G02B 6/36 (20130101) G02B 6/3604 (20130101) Original (OR) Class G02B 6/4268 (20130101) G02B 6/4296 (20130101) G02B 6/4415 (20130101) G02B 6/4436 (20130101) G02B 6/4458 (20130101) G02B 7/005 (20130101) G02B 7/1827 (20130101) G02B 19/0052 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/00 (20130101) H01L 35/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 17/00 (20130101)
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09385163 — Addressable SiOX memory array with incorporated diodes

US 09385163	Tour et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) NASA Shared Services Center (NSSC)
APPLICANT(S)	James M. Tour (Bellaire, Texas); Jun Yao (Allston, Massachusetts); Jian Lin (Houston, Texas); Gunuk Wang (Houston, Texas); Krishna Palem (Houston, Texas)
ASSIGNEE(S)	WILLIAM MARSH RICE UNIVERSITY (Houston, Texas); NANYANG TECHNOLOGICAL UNIVERSITY (Singapore, Singapore)
INVENTOR(S)	James M. Tour (Bellaire, Texas); Jun Yao (Allston, Massachusetts); Jian Lin (Houston, Texas); Gunuk Wang (Houston, Texas); Krishna Palem (Houston, Texas)
ABSTRACT	Various embodiments of the resistive memory cells and arrays discussed herein comprise: (1) a first electrode; (2) a second electrode; (3) resistive memory material; and (4) a diode. The resistive memory material is selected from the group consisting of SiO_x, SiO_xH, SiO_xN_y, SiO_xN_yH, SiO_xC_z, SiO_xC_zH, and combinations thereof, wherein each of x, y and z are equal to or greater than 1 and equal to or less than 2. The diode may be any suitable diode, such as n-p diodes, p-n diodes, and Schottky diodes.
FILED	Monday, August 27, 2012
APPL NO	14/240973
ART UNIT	2822 — Semiconductors/Memory
CURRENT CPC	Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/2409 (20130101) H01L 27/2463 (20130101) Original (OR) Class H01L 29/872 (20130101) H01L 29/8611 (20130101) H01L 29/8613 (20130101) H01L 29/66136 (20130101) H01L 29/66143 (20130101) H01L 45/04 (20130101) H01L 45/145 (20130101) H01L 45/1233 (20130101) H01L 45/1253 (20130101) H01L 45/1608 (20130101) H01L 45/1616 (20130101) H01L 45/1625 (20130101) H01L 45/1675 (20130101)
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09385832 — Methodology and method and apparatus for signaling with capacity optimized constellations

US 09385832	Barsoum et al.
FUNDED BY	National Aeronautics and Space Administration (NASA)
APPLICANT(S)	Constellation Designs, Inc. (Pacific Palisades, California)
ASSIGNEE(S)	Constellation Designs, Inc. (Pacific Palisades, California)
INVENTOR(S)	Maged F. Barsoum (Saratoga, California); Christopher R. Jones (Pacific Palisades, California)
ABSTRACT	Design Methodology and Method and Apparatus for Signaling with Capacity Optimized Constellation Abstract Communication systems are described that use geometrically PSK shaped constellations that have increased capacity compared to conventional PSK constellations operating within a similar SNR band. The geometrically shaped PSK constellation is optimized based upon parallel decoding capacity. In many embodiments, a capacity optimized geometrically shaped constellation can be used to replace a conventional constellation as part of a firmware upgrade to transmitters and receivers within a communication system. In a number of embodiments, the geometrically shaped constellation is optimized for an Additive White Gaussian Noise channel or a fading channel. In numerous embodiments, the communication uses adaptive rate encoding and the location of points within the geometrically shaped constellation changes as the code rate changes.
FILED	Friday, September 19, 2014
APPL NO	14/491731
ART UNIT	2634 — Digital Communications
CURRENT CPC	Transmission H04B 15/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) Original (OR) Class H04L 1/0009 (20130101) H04L 27/3405 (20130101)
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RE046054 — Underwater vehicle with sonar array

US RE46054	Stone et al.
FUNDED BY	National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC)
APPLICANT(S)	Piedra Sombra Corporation, Inc. (Del Valle, Texas)
ASSIGNEE(S)	Piedra Sombra Corporation, Inc. (Del Valle, Texas)
INVENTOR(S)	William C. Stone (Del Valle, Texas); Bartholomew P. Hogan (Rockville, Maryland)
ABSTRACT	An underwater vehicle including an axi-symmetric framing system rotatable about a centerline to define a shell of revolution having a uniformly-convex outer boundary. A narrow-beam sonar array is mounted on the axi-symmetric framing system, and includes a multitude of simultaneously-fireable and/or asynchronously-fireable transducers distributed substantially evenly over a 4π-steradian viewing angle. The present invention provides the necessary configuration for a vehicle wherein an internal algorithm can compare a “new” geometry to an “old” geometry collected earlier to construct a best fit of the new world map with the old world map and locate the vehicle within the context of the new world map. This then provides a completely independent mechanism for correction of the gradual drift in x and y that is not dependent on any form of external navigation aid.
FILED	Monday, March 31, 2014
APPL NO	14/230123
ART UNIT	3993 — Central Reexamination Unit (Mechanical)
CURRENT CPC	Ships or Other Waterborne Vessels; Equipment for Shipping B63B 3/13 (20130101) Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 11/42 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/521 (20130101) Original (OR) Class G01S 15/93 (20130101) G01S 15/8922 (20130101)
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Department of Agriculture (USDA)

09381240 — Recombinant low virulence bovine herpesvirus-1 (BoHV-1) vaccine vectors

US 09381240	Mahony
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	Timothy John Mahony (Bellbowrie, Australia)
ASSIGNEE(S)	THE STATE OF QUEENSLAND ACTING THROUGH THE DEPARTMENT OF AGRICULTURE AND FISHERIES (Brisbane, Queensland, Australia); MEAT and LIVESTOCK AUSTRALIA LIMITED (North Sydney, New South Wales, Australia)
INVENTOR(S)	Timothy John Mahony (Bellbowrie, Australia)
ABSTRACT	The present disclosure teaches generally in the field of vaccination and disease control in cattle and bovine animals. A recombinant bovine herpesvirus 1 (BoHV-1) vaccine vector is provided for efficient control of one or more bovine pathogens such as those associated with bovine respiratory disease complex, such as bovine viral diarrhea virus (BVDV), and which ameliorates disease conditions caused thereby. Protocols for the management of confined or herded bovine animals are also enabled herein.
FILED	Wednesday, July 04, 2012
APPL NO	14/130904
ART UNIT	1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/70 (20130101) A61K 2039/543 (20130101) A61K 2039/552 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/16734 (20130101) C12N 2710/16743 (20130101) C12N 2770/24334 (20130101) C12N 2800/204 (20130101)
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09382554 — Methods for isoprene and pinene production in cyanobacteria

US 09382554	Kallas et al.
FUNDED BY	Department of Defense (DOD) Department of the Army (DOA) Combat Capabilities Development Command (CCDC) Army Research Laboratory (CCDC ARL) Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA)
APPLICANT(S)	Toivo Kallas (Oshkosh, Wisconsin); Matthew Nelson (Oshkosh, Wisconsin); Eric Singsaas (Stevens Point, Wisconsin)
ASSIGNEE(S)	WISYS TECHNOLOGY FOUNDATION, INC. (Madison, Wisconsin)
INVENTOR(S)	Toivo Kallas (Oshkosh, Wisconsin); Matthew Nelson (Oshkosh, Wisconsin); Eric Singsaas (Stevens Point, Wisconsin)
ABSTRACT	Methods of isoprenoid production are provided by the present invention. In particular, transgenic Synechococcus sp. PCC 7002 cyanobacteria and methods for producing isoprene and pinene using a host transgenic Synechococcus sp. PCC 7002 cyanobacterium are provided.
FILED	Friday, July 26, 2013
APPL NO	13/952071
ART UNIT	1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/90 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 5/007 (20130101) C12P 5/026 (20130101) Original (OR) Class Enzymes C12Y 402/03027 (20130101) C12Y 503/03002 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101)
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09382566 — Fermentative production of sophorolipids from soybean and other vegetable oils

US 09382566	Kurtzman et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S)	Cletus P. Kurtzman (Peoria, Illinois); Neil P. Price (Edelstein, Illinois); Karen J. Ray (East Peoria, Illinois); Tsung Min Kuo (Ballston Lake, New York)
ABSTRACT	Open chain sophorolipids may be produced by fermentation with Candida sp. NRRL Y-27208 or C. riodocensis. Dimers and trimers of sophorolipids are also produced. The sophorolipds are produced by inoculating a fermentation medium comprising a carbon source and a lipid, with Candida riodocensis or Candida species NRRL Y-27208, and incubating under aerobic conditions and for a period of time effective to produce an open chain sophorolipid in the medium. The sophorolipids may be subsequently recovered from the fermentation medium.
FILED	Monday, September 30, 2013
APPL NO	14/041786
ART UNIT	1673 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC	Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/04 (20130101) C07H 15/06 (20130101) C07H 15/10 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/44 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 1/22 (20130101) C12R 1/72 (20130101)
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PP026899 — Blueberry plant named ‘Pinnacle’

US PP26899	Draper et al.
FUNDED BY	Department of Agriculture (USDA)
APPLICANT(S)	North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S)	NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia)
INVENTOR(S)	Arlen D. Draper (Payson, Arizona); James Ralph Ballington (Cary, North Carolina); Charles Michael Mainland (Wilmington, North Carolina); William Terry Bland (Wilmington, North Carolina)
ABSTRACT	‘Pinnacle’ is a new and distinct variety of blueberry plant that has the following unique combination of desirable features outstanding in a new variety. ‘Pinnacle’ provides season ripening when prices remain high and consistently good yields of large size fruit. In addition, ‘Pinnacle’ provides high percentages of fruit in very large diameter categories, which are tailored for premium market outlets, very good fruit color and quality, excellent fruit firmness and fruit with very good post-harvest shelf-life.
FILED	Friday, May 16, 2014
APPL NO	14/120395
ART UNIT	1661 — Plants
CURRENT CPC	Plants PLT/157
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Small Business Administration (SBA)

09380769 — Transgenic chicken comprising an inactivated immunoglobulin gene

US 09380769	Leighton et al.
FUNDED BY	Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Phil Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California)
ASSIGNEE(S)	Crystal Bioscience Inc. (Emeryville, California)
INVENTOR(S)	Phil Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California)
ABSTRACT	A transgenic chicken comprising an inactivated heavy immunoglobulin gene and/or inactivated light chain immunoglobulin gene is provided, as well as cells and targeting vectors for making the same.
FILED	Wednesday, May 23, 2012
APPL NO	14/114159
ART UNIT	1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC	Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Original (OR) Class A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/902 (20130101)
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09381568 — System and method for making structured magnetic material from insulated particles

US 09381568	Hosek et al.
FUNDED BY	National Science Foundation (NSF) Directorate for Engineering (ENG) Division of Industrial Innovation and Partnerships (IIP) Small Business Administration (SBA) Small Business Innovation Research (SBIR)
APPLICANT(S)	Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts)
ASSIGNEE(S)	Persimmon Technologies Corporation (Wakefield, Massachusetts)
INVENTOR(S)	Martin Hosek (Lowell, Massachusetts); Sripati Sah (Wakefield, Massachusetts)
ABSTRACT	A system for making a material having domains with insulated boundaries is provided. The system includes a combustion chamber, a gas inlet configured to inject a gas into the combustion chamber, a fuel inlet configured to inject a fuel into the combustion chamber, an igniter subsystem configured to ignite a mixture of the gas and the fuel to create a predetermined temperature and pressure in the combustion chamber, a metal powder inlet configured to inject a metal powder comprised of particles coated with an electrically insulating material into the combustion, wherein the predetermined temperature creates conditioned droplets comprised of the metal powder in the chamber, and an outlet configured to eject and accelerate combustion gases and the conditioned droplets from the combustion chamber and towards a surface such that conditioned droplets adhere to the surface to form a material having domains with insulated boundaries thereon.
FILED	Friday, June 29, 2012
APPL NO	13/507451
ART UNIT	1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC	Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Original (OR) Class Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/115 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/18 (20130101) C23C 6/00 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/24 (20130101) H01F 3/08 (20130101) H01F 41/0246 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24413 (20150115)
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Department of Justice (DOJ)

09383439 — Detection of conductive material in a thin film

US 09383439	Buxton et al.
FUNDED BY	Department of Justice (DOJ) Federal Bureau of Investigation (FBI)
APPLICANT(S)	Federal Bureau of Investigation (Washington, District of Columbia)
ASSIGNEE(S)	The United States of America as represented by the Federal Bureau of Investigation, Dept. of Justice (Washington, District of Columbia)
INVENTOR(S)	Carey G Buxton (Spotslyvania, Virginia); John Scott Huggins (Warrenton, Virginia)
ABSTRACT	Provided are products used to detect and methods for detecting conductive materials in the presence of non-conductive materials, including non-conductive materials having dielectric properties. Specifically, the product is a conductive thin film detector, which is, preferably, a hand-held device designed to detect the presence of metal in, on, or under an object. This detection occurs even in the presence of non-conductive materials and other nearby conductive materials on objects that are not being tested. The device preferably includes: a power source, such as a battery; a method for activation, such as a press button; the necessary components to send and receive a radio frequency, e.g., a radio frequency generator, an antenna, and a radio frequency detector; and an indicator, such as a light or a meter, to, for example, indicate the strength of the radio frequency signal received.
FILED	Friday, June 27, 2014
APPL NO	14/317414
ART UNIT	2867 — Printing/Measuring and Testing
CURRENT CPC	Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/04 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/12 (20130101)
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Department of Veterans Affairs (DVA)

09382376 — Use of polymer D-lactic acid (PDLA) or equivalents thereof to inhibit growth of cancer cells and diagnose cancers

US 09382376	Goldberg et al.
FUNDED BY	Department of Veterans Affairs (DVA)
APPLICANT(S)	Joel S. Goldberg (Durham, North Carolina); Joe Brice Weinberg (Durham, North Carolina)
ASSIGNEE(S)	The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S)	Joel S. Goldberg (Durham, North Carolina); Joe Brice Weinberg (Durham, North Carolina)
ABSTRACT	The invention provides method for sequestering or trapping L-lactate in or near a tumor cell comprising contacting an isolated polymer of D-lactic acid (PDLA) or an equivalent, derivative or analog thereof with the tumor cell so that the PDLA binds L-lactate in or near the cell and thereby sequestering or trapping L-lactate in or near the tumor cells.
FILED	Tuesday, October 21, 2014
APPL NO	14/520089
ART UNIT	1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC	Preparations for Medical, Dental, or Toilet Purposes A61K 31/765 (20130101) Acyclic or Carbocyclic Compounds C07C 59/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 2533/40 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/57407 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

European Union (EU)

09383303 — Apparatus and method for carrying out in a controlled atmosphere material fatigue tests in a high cycle regime with a controlled strain ratio

US 09383303	Bruchhausen et al.
FUNDED BY	European Union (EU)
APPLICANT(S)	Matthias Bruchhausen (Alkmaar, Netherlands); Peter Hahner (Alkmaar, Netherlands); Burkhard Fischer (Schagen, Netherlands); Daniel Cornu (Mantes la Jolie, France); Christophe Hurel (Limay, France); Jean-Pierre Lecornu (Courcelles sur Seine, France)
ASSIGNEE(S)	SNECMA (Paris, France); THE EUROPEAN UNION represented by the European Commission (Brussels, Belgium)
INVENTOR(S)	Matthias Bruchhausen (Alkmaar, Netherlands); Peter Hahner (Alkmaar, Netherlands); Burkhard Fischer (Schagen, Netherlands); Daniel Cornu (Mantes la Jolie, France); Christophe Hurel (Limay, France); Jean-Pierre Lecornu (Courcelles sur Seine, France)
ABSTRACT	An apparatus for carrying out high cycle fatigue tests of a specimen under high pressure, including: a pressure vessel; a load train including a first horn and a second horn between which a specimen is to be arranged, wherein the load train is arranged within an internal chamber of the pressure vessel; and a converter configured to apply ultrasonic waves into the load train by exciting the first horn to apply a dynamic stress to the specimen. A base part of the second horn is movably seated in the pressure vessel such that two separated chambers are formed within the pressure vessel with the first chamber for the specimen, wherein both chambers can be fed with gas and charged with different gas pressures in order to apply a static stress to the specimen.
FILED	Friday, July 22, 2011
APPL NO	14/234274
ART UNIT	2856 — Printing/Measuring and Testing
CURRENT CPC	Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/12 (20130101) G01N 3/32 (20130101) Original (OR) Class G01N 3/38 (20130101) G01N 2203/005 (20130101) G01N 2203/0008 (20130101) G01N 2203/023 (20130101) G01N 2203/0073 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Geospatial Intelligence Agency (NGA)

09385738 — Digital readout method and apparatus

US 09385738	Kelly et al.
FUNDED BY	Department of Defense (DOD) Department of the Air Force (DAF) Air Force Materiel Command (AFMC) National Geospatial Intelligence Agency (NGA)
APPLICANT(S)	Michael Kelly (North Reading, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexington, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ASSIGNEE(S)	Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S)	Michael Kelly (North Reading, Massachusetts); Daniel Mooney (Dracut, Massachusetts); Curtis Colonero (Shrewsbury, Massachusetts); Robert Berger (Lexington, Massachusetts); Lawrence Candell (Arlington, Massachusetts)
ABSTRACT	Autonomously operating analog to digital converters are formed into a two dimensional array. The array may incorporate digital signal processing functionality. Such an array is particularly well-suited for operation as a readout integrated circuit and, in combination with a sensor array, forms a digital focal plane array.
FILED	Monday, December 08, 2014
APPL NO	14/563271
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 1/60 (20130101) H03M 1/145 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/3355 (20130101) H04N 5/37455 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

National Security Agency (NSA)

09383080 — Wide field of view concentrator

US 09383080	McGarvey et al.
FUNDED BY	National Security Agency (NSA)
APPLICANT(S)	National Security Agency (Ft. George G. Meade, Maryland)
ASSIGNEE(S)	The United States of America as represented by the Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S)	Brian S. McGarvey (Arnold, Maryland); David J. Ortiz (Severna Park, Maryland); Mario A. Serna (Palmer Lake, Colorado)
ABSTRACT	The present invention is a system that offers a capability to concentrate light from a large focal point onto a small spot on a detector. The system also offers off-axis capability should the system be moved, poorly pointed, off axis or jostled while in use. As designed, the present invention includes a half-ball lens having a front end and a back end, a compound parabolic concentrator (CPC) having a front end and a back end, wherein the front end of said CPC is adjacent to the back end of the half-ball lens such that the CPC is centered against the back end of the half-ball lens, and a detector, wherein the detector is adjacent to the back end of the CPC.
FILED	Wednesday, May 21, 2014
APPL NO	14/120660
ART UNIT	2878 — Optics
CURRENT CPC	Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 5/045 (20130101) F21V 7/06 (20130101) Original (OR) Class F21V 13/04 (20130101) Optical Elements, Systems, or Apparatus G02B 26/02 (20130101) G02B 27/40 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

U.S. State Government

09383120 — Solar thermal concentrator apparatus, system, and method

US 09383120	Winston
FUNDED BY	U.S. State Government State of California California Energy Commission (CEC)
APPLICANT(S)	Roland Winston (Merced, California)
ASSIGNEE(S)	Roland Winston (Merced, California)
INVENTOR(S)	Roland Winston (Merced, California)
ABSTRACT	An apparatus is disclosed including: a trough shaped reflector extending along a longitudinal axis and including at least one reflective surface having a shape which substantially corresponds to an edge ray involute of the absorber.
FILED	Friday, March 20, 2015
APPL NO	14/663457
ART UNIT	3749 — Static Structures, Supports and Furniture
CURRENT CPC	Producing or Use of Heat Not Otherwise Provided For F24J 2/05 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

United States Postal Service (USPS)

09381544 — Apparatus and methods for identifying and processing mail using an identification code

US 09381544	Avant et al.
FUNDED BY	United States Postal Service (USPS)
APPLICANT(S)	UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
ASSIGNEE(S)	UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S)	Oscar Lee Avant (Silver Spring, Maryland); Ralph William Boldt, Jr. (Monrovia, Maryland); Bruce A. Brandt (Gainesville, Virginia); Jay David Fadely (Palmetto, Florida); Michael Ray Little (Fairfax, Virginia); Simon Franklin Reidel (Rockville, Maryland)
ABSTRACT	Apparatus and methods consistent with the present invention provide for identifying and processing mail using an identification code on a mailpiece as a redundant source of identification information in a mail sorting system. In one embodiment, this information is stored in a temporary database and used for the identification and processing of mail in a Remote Bar Code System (RBCS). In this embodiment, the identification code enables the automation of mail sorting and other processing tasks, reducing costs and delays in mail delivery services. In another embodiment, the identification and processing of mail occurs in an Identification Code Sorting (ICS) system. In this embodiment, a long-term database allows for mail sorting and other processing tasks on a national or global level.
FILED	Thursday, December 05, 2013
APPL NO	14/097349
ART UNIT	3653 — Miscellaneous Articles, Stock Material
CURRENT CPC	Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/10 (20130101) Original (OR) Class B07C 3/18 (20130101) B07C 3/20 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

Government Rights Acknowledged

09385742 — Wideband multi-mode current switch for digital to analog converter

US 09385742	Cheng et al.
FUNDED BY
APPLICANT(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S)	RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S)	William W. Cheng (Redondo Beach, California); Michael H. Liou (Granada Hills, California)
ABSTRACT	A current switching cell for a digital to analog converter. The switching cell includes three stages, a first control stage, a data stage, and a second control stage. The first control stage is configured to either disconnect the outputs of the digital to analog converter, or to connect them to the outputs of the data stage. The data stage is configured to operate in one of two states, depending on a data signal received, and the second control stage is configured to selectively invert the output of the digital to analog converter. The two control stages may be driven with several combinations of control waveforms to implement a non return to zero mode, a return to zero mode, inverse non return to zero mode, and inverse return to zero mode.
FILED	Monday, November 16, 2015
APPL NO	14/942723
ART UNIT	2845 — Electrical Circuits and Systems
CURRENT CPC	Coding; Decoding; Code Conversion in General H03M 1/66 (20130101) Original (OR) Class
VIEW PATENT	@ USPTO: Full Text PDF

09386504 — Energy-efficient network protocol and node device for sensor networks

US 09386504	Yoon
FUNDED BY
APPLICANT(S)	Chang-June C. J. Yoon (Edison, New Jersey)
ASSIGNEE(S)	Exelis, Inc. (McLean, Virginia)
INVENTOR(S)	Chang-June C. J. Yoon (Edison, New Jersey)
ABSTRACT	An “on-demand” approach for a routing protocol for a wireless network that achieves balanced energy consumption among all participating nodes in the network. Synchronization messages transmitted by nodes associated with an upstream node include local node information (LNI) that a node can use to repair or bypass a lost upstream node in a real or virtual (temporary) manner depending upon the local node's battery level. Only if a repair process fails will a global re-organization (Re-Org) be initiated. The LNI also allows for nodes having lower power availability (battery level) not to transmit the LNI so that unaffiliated node(s) can select an upstream node having more power availability thereby extending network life.
FILED	Monday, March 29, 2010
APPL NO	12/748558
ART UNIT	2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC	Wireless Communication Networks H04W 40/10 (20130101) H04W 40/28 (20130101) Original (OR) Class H04W 52/0219 (20130101) H04W 56/00 (20130101) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 60/50 (20130101)
VIEW PATENT	@ USPTO: Full Text PDF

How To Use This Page

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, July 05, 2016.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

A61B 1/149 (20130101)
A61B 1/71 (20130101)
A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2016/fedinvent-patents-20160705.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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